locus_tag old_locus_tag gene Name start end strand product note type ID NCBI UM146_RS00005 UM146_RS00005 UM146_RS00005 4991242 4993797 + 23S ribosomal RNA rRNA gene0 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00005 UM146_RS00010 UM146_r23989 UM146_RS00010 869 984 + 5S ribosomal RNA rRNA gene1 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00010 UM146_RS00015 UM146_t23817 UM146_RS00015 999 1074 + tRNA-Thr tRNA gene2 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00015 UM146_RS00020 UM146_r23991 UM146_RS00020 1114 1229 + 5S ribosomal RNA rRNA gene3 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00020 UM146_RS00025 UM146_00005 UM146_RS00025 1292 2050 - arginine ABC transporter ATP-binding protein gene gene4 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00025 UM146_RS00030 UM146_00010 UM146_RS00030 2058 3161 - amino acid ABC transporter permease gene gene5 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00030 UM146_RS00035 UM146_00015 UM146_RS00035 3171 4352 - amino acid ABC transporter permease gene gene6 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00035 UM146_RS00040 UM146_00020 UM146_RS00040 4420 5445 - amino acid ABC transporter substrate-binding protein gene gene7 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00040 UM146_RS00045 UM146_RS00045 UM146_RS00045 5474 5650 - hypothetical protein gene gene8 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00045 UM146_RS00050 UM146_00025 UM146_RS00050 5876 6097 - membrane protein gene gene9 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00050 UM146_RS00055 UM146_00030 UM146_RS00055 6203 6328 + hypothetical protein gene gene10 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00055 UM146_RS00060 UM146_00035 UM146_RS00060 6350 9454 - multidrug efflux RND transporter permease subunit gene gene11 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00060 UM146_RS00065 UM146_00040 UM146_RS00065 9466 10623 - MexX family efflux pump subunit with AcrD and TolC forms a transport system involved in resistance to a number of compounds including lipophilic antibiotics gene gene12 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00065 UM146_RS00070 UM146_00045 UM146_RS00070 11025 11687 + acrEF/envCD operon repressor gene gene13 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00070 UM146_RS00075 UM146_00050 UM146_RS00075 11690 11869 - transporter gene gene14 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00075 UM146_RS00080 UM146_00055 UM146_RS00080 11953 12837 - methyltransferase gene gene15 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00080 UM146_RS00085 UM146_00060 fis fis 12925 13221 - Fis family transcriptional regulator Stimulates excision of phage lambda%3B affects Mu development%3B acts as an activator of rRNA and iRNA transcription gene gene16 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00085 UM146_RS00090 UM146_00065 UM146_RS00090 13247 14212 - tRNA-dihydrouridine synthase B gene gene17 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00090 UM146_RS00095 UM146_00070 prmA prmA 14541 15422 - ribosomal protein L11 methyltransferase methylates ribosomal protein L11 at multiple amino acid positions%3B mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype gene gene18 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00095 UM146_RS00100 UM146_00075 panF panF 15434 16885 - sodium:pantothenate symporter mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions%3B member of SSS family of sodium/solute symporters%3B the imported panthothenate is phosphorylated by panthothenate kinase gene gene19 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00100 UM146_RS00105 UM146_00080 UM146_RS00105 16875 17117 - membrane protein gene gene20 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00105 UM146_RS00110 UM146_00085 UM146_RS00110 17210 18145 - sugar kinase gene gene21 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00110 UM146_RS00115 UM146_00090 UM146_RS00115 18177 19007 - DeoR family transcriptional regulator gene gene22 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00115 UM146_RS00120 UM146_00095 gatY gatY 19348 20202 + fructose-bisphosphate aldolase catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1%2C6-bisphosphate%3B in enteric bacteria there are two D-tagatose 1%2C6-bisphosphate-specific aldolases: KbaY (also called AgaY)%2C involved in catabolism of N-acetyl-galactosamine and D-galactosamine%2C and GatY which is part of the galactitol catabolism pathway gene gene23 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00120 UM146_RS00125 UM146_00100 UM146_RS00125 20238 21128 + sugar ABC transporter gene gene24 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00125 UM146_RS00130 UM146_00105 UM146_RS00130 21189 22688 + D-ribose transporter ATP-binding protein with RbsBCD acts to import ribose into the cell%3B RbsA contains 2 ATP-binding domain gene gene25 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00130 UM146_RS00135 UM146_00110 UM146_RS00135 22689 23678 + sugar ABC transporter permease gene gene26 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00135 UM146_RS00140 UM146_RS00140 UM146_RS00140 23700 24661 + sugar kinase gene gene27 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00140 UM146_RS00145 UM146_00125 UM146_RS00145 24658 25704 + hypothetical protein gene gene28 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00145 UM146_RS00150 UM146_00130 UM146_RS00150 25796 27145 - acetyl-CoA carboxylase biotin carboxylase subunit an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase%2C an enzyme that catalyzes the formation of malonyl-CoA%2C which in turn controls the rate of fatty acid metabolism gene gene29 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00150 UM146_RS00155 UM146_00135 UM146_RS00155 27156 27626 - acetyl-CoA carboxylase biotin carboxyl carrier protein subunit composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex%2C the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%2C which in turn controls the rate of fatty acid metabolism gene gene30 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00155 UM146_RS00160 UM146_00140 UM146_RS00160 28031 28195 - hypothetical protein gene gene31 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00160 UM146_RS00170 UM146_RS00170 UM146_RS00170 28445 28546 + hypothetical protein gene gene32 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00170 UM146_RS00175 UM146_00145 UM146_RS00175 28604 29578 - quinone oxidoreductase gene gene33 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00175 UM146_RS00180 UM146_00150 UM146_RS00180 29730 31670 + hypothetical protein regulates the degradation of the small RNAs CsrB and CsrC%3B may function to targate RNase E to specific RNA molecules gene gene34 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00180 UM146_RS00185 UM146_RS00185 UM146_RS00185 31679 31867 - hypothetical protein gene gene35 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00185 UM146_RS00190 UM146_00155 UM146_RS00190 31975 33018 + rod shape-determining protein MreB gene gene36 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00190 UM146_RS00195 UM146_00160 UM146_RS00195 33084 34187 + rod shape-determining protein MreC in some organisms this protein is a transmembrane protein while in others it is periplasmic%3B involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall gene gene37 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00195 UM146_RS00200 UM146_00170 UM146_RS00200 34187 34675 + rod shape-determining protein MreD part of cell wall structural complex MreBCD%3B transmembrane component gene gene38 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00200 UM146_RS00205 UM146_00175 UM146_RS00205 34684 35277 + septum formation inhibitor Maf Maf%3B overexpression in Bacillus subtilis inhibits septation in the dividing cell gene gene39 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00205 UM146_RS00210 UM146_00180 UM146_RS00210 35267 36736 + ribonuclease G involved in the processing of the 5'end of 16S rRNA gene gene40 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00210 UM146_RS00215 UM146_00185 UM146_RS00215 36804 40604 + membrane protein gene gene41 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00215 UM146_RS00220 UM146_00190 tldD tldD 40760 42205 + protease TldD responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17%2C an exported protein that targets the essential topoisomerase II DNA gyrase%3B degrades the E. coli plasmid F-encoded CcdA gene gene42 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00220 UM146_RS00225 UM146_00195 UM146_RS00225 42333 43262 - HTH-type transcriptional activator AaeR for aaeXAB operon gene gene43 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00225 UM146_RS00230 UM146_00200 UM146_RS00230 43445 43648 + protein AaeX membrane protein AaeX%3B the gene is a member of the aaeXAB operon gene gene44 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00230 UM146_RS00235 UM146_00205 UM146_RS00235 43656 44588 + p-hydroxybenzoic acid efflux pump subunit AaeA with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid%2C 6-hydroxy-2-naphthoic and 2-hydroxycinnamate gene gene45 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00235 UM146_RS00240 UM146_00210 UM146_RS00240 44594 46561 + p-hydroxybenzoic acid efflux pump subunit AaeB with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate gene gene46 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00240 UM146_RS00245 UM146_00215 UM146_RS00245 46653 46925 + barnase inhibitor gene gene47 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00245 UM146_RS00250 UM146_00220 UM146_RS00250 46980 47243 - membrane protein gene gene48 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00250 UM146_RS00255 UM146_00225 UM146_RS00255 47607 48077 - arginine repressor regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes gene gene49 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00255 UM146_RS00260 UM146_00230 UM146_RS00260 48512 49450 + malate dehydrogenase oxidizes malate to oxaloacetate gene gene50 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00260 UM146_RS00265 UM146_00235 UM146_RS00265 49512 50579 - serine endoprotease DegS gene gene51 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00265 UM146_RS00270 UM146_00240 UM146_RS00270 50669 52036 - serine endoprotease DegQ gene gene52 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00270 UM146_RS00275 UM146_00245 UM146_RS00275 52190 52588 - hypothetical protein gene gene53 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00275 UM146_RS00280 UM146_00250 UM146_RS00280 52782 53909 + hypothetical protein gene gene54 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00280 UM146_RS00285 UM146_00255 UM146_RS00285 54129 54557 + 50S ribosomal protein L13 gene gene55 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00285 UM146_RS00290 UM146_00260 UM146_RS00290 54573 54965 + 30S ribosomal protein S9 gene gene56 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00290 UM146_RS00295 UM146_00265 sspA sspA 55360 55998 + stringent starvation protein A transcriptional activator%3B required for activation of bacteriophage P1 late promoter%3B induced by starvation gene gene57 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00295 UM146_RS00300 UM146_00270 UM146_RS00300 56004 56501 + peptidase gene gene58 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00300 UM146_RS00305 UM146_00275 UM146_RS00305 56609 57400 + transcriptional regulator NanR Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization gene gene59 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00305 UM146_RS00310 UM146_00280 UM146_RS00310 57522 58415 + N-acetylneuraminate lyase catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid gene gene60 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00310 UM146_RS00315 UM146_00285 UM146_RS00315 58524 60014 + sialic acid transporter gene gene61 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00315 UM146_RS00320 UM146_00290 UM146_RS00320 60062 60751 + N-acetylmannosamine-6-P epimerase Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate gene gene62 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00320 UM146_RS00325 UM146_00295 UM146_RS00325 60748 61623 + N-acetylmannosamine kinase catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein gene gene63 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00325 UM146_RS00330 UM146_00300 UM146_RS00330 61620 62084 + hypothetical protein gene gene64 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00330 UM146_RS00335 UM146_00305 UM146_RS00335 62152 63570 - glutamate synthase subunit beta gene gene65 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00335 UM146_RS00340 UM146_00310 gltB gltB 63583 67791 - glutamate synthase subunit alpha catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate gene gene66 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00340 UM146_RS00345 UM146_RS00345 UM146_RS00345 67812 68042 - glutamine amidotransferase gene gene67 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00345 UM146_RS00350 UM146_00325 UM146_RS00350 68717 69646 + radical SAM protein gene gene68 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00350 UM146_RS00355 UM146_00330 UM146_RS00355 69742 72078 + PAS domain-containing two-component system sensor histidine kinase/response regulator sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon%3B hybrid sensory histidine kinase in two-component regulatory system with ArcA gene gene69 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00355 UM146_RS00360 UM146_00335 UM146_RS00360 72308 72961 + isoprenoid biosynthesis protein gene gene70 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00360 UM146_RS00365 UM146_00340 mtgA mtgA 72958 73686 + monofunctional biosynthetic peptidoglycan transglycosylase glycosyltransferase%3B polymerizes glycan strands in the peptidoglycan gene gene71 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00365 UM146_RS00370 UM146_00345 UM146_RS00370 73683 74315 - hypothetical protein gene gene72 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00370 UM146_RS00375 UM146_00350 UM146_RS00375 74529 74801 - phosphocarrier protein NPr gene gene73 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00375 UM146_RS00380 UM146_00355 UM146_RS00380 74798 75652 - glmZ(sRNA)-inactivating NTPase glucosamine-6-phosphate regulated%3B inactivates the glmS upregulator glmZ gene gene74 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00380 UM146_RS00385 UM146_00360 UM146_RS00385 75698 76189 - PTS sugar transporter subunit IIA involved in nitrogen metabolism%3B protein IIA is phosphorylated by enzyme I(Ntr) gene gene75 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00385 UM146_RS00390 UM146_00365 UM146_RS00390 76307 76594 - ribosome hibernation promoting factor YhbH%3B resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase%3B binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization)%3B seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing gene gene76 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00390 UM146_RS00395 UM146_00370 UM146_RS00395 76617 78050 - RNA polymerase sigma-54 factor sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism%3B the rhizobia often have 2 copies of this sigma factor%3B in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation%3B in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions%2C rpoN1 gene was regulated in response to oxygen gene gene77 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00395 UM146_RS00400 UM146_00375 UM146_RS00400 78098 78823 - LPS export ABC transporter ATP-binding protein gene gene78 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00400 UM146_RS00405 UM146_00380 UM146_RS00405 78830 79387 - LPS export system protein LptA LptA%3B periplasmic binding protein part of a putative ABC superfamily of uptake transporters%3B interacts with LptB protein%2C the ATP binding component of the uptake system gene gene79 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00405 UM146_RS00410 UM146_00385 UM146_RS00410 79356 79931 - LPS export ABC transporter periplasmic protein LptC gene gene80 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00410 UM146_RS00415 UM146_00390 UM146_RS00415 79928 80494 - 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC forms homotetramers%3B catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate%3B functions in lipopolysaccharide biosynthesis gene gene81 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00415 UM146_RS00420 UM146_00395 UM146_RS00420 80515 81501 - arabinose 5-phosphate isomerase KdsD gene gene82 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00420 UM146_RS00425 UM146_00400 UM146_RS00425 81515 82492 - hypothetical protein YrbG%3B inner membrane protein involved in cell envelope integrity%3B putative sodium ion/calcium ion exchanger%3B in E. coli it is non essential for cell viability%3B member of the YRBG family of cation/Ca2+ exchangers gene gene83 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00425 UM146_RS00430 UM146_00405 UM146_RS00430 82702 83511 + phospholipid import ATP-binding protein ABC transporter maintaining outer membrane lipid asymmetry gene gene84 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00430 UM146_RS00435 UM146_00410 UM146_RS00435 83519 84301 + phospholipid ABC transporter permease gene gene85 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00435 UM146_RS00440 UM146_00415 UM146_RS00440 84306 84857 + outer membrane lipid asymmetry maintenance protein MlaD gene gene86 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00440 UM146_RS00445 UM146_00420 UM146_RS00445 84876 85511 + organic solvent ABC transporter substrate-binding protein involved in maintaining outer membrane lipid asymmetry gene gene87 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00445 UM146_RS00450 UM146_00425 UM146_RS00450 85511 85804 + phospholipid ABC transporter substrate-binding protein gene gene88 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00450 UM146_RS00455 UM146_00430 UM146_RS00455 85964 86218 + acid stress protein IbaG gene gene89 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00455 UM146_RS00460 UM146_00435 UM146_RS00460 86273 87532 + UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene90 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00460 UM146_RS00465 UM146_00440 UM146_RS00465 87580 87858 - transcriptional regulator activator of maltose metabolism genes gene gene91 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00465 UM146_RS00470 UM146_00445 UM146_RS00470 88091 89062 - octaprenyl-diphosphate synthase gene gene92 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00470 UM146_RS00475 UM146_00450 rplU rplU 89320 89631 + 50S ribosomal protein L21 gene gene93 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00475 UM146_RS00480 UM146_00455 rpmA rpmA 89652 89909 + 50S ribosomal protein L27 involved in the peptidyltransferase reaction during translation gene gene94 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00480 UM146_RS00485 UM146_00460 UM146_RS00485 90036 91001 + membrane protein gene gene95 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00485 UM146_RS00490 UM146_00465 obgE obgE 91017 92177 + GTPase Obg ObgE%3B essential GTPase%3B exhibits high exchange rate for GTP/GDP%3B associates with 50S ribosomal subunit%3B involved in regulation of chromosomal replication gene gene96 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00490 UM146_RS00495 UM146_00470 UM146_RS00495 92218 93651 - D-alanyl-D-alanine carboxypeptidase penicillin binding protein 4%3B penicillin sensitive%3B catalyzes the formation of D-alanine from D-alanyl-D-alanine%3B one of four%2C DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains gene gene97 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00495 UM146_RS00500 UM146_00475 greA greA 93899 94375 + transcription elongation factor GreA necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites%3B arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus gene gene98 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00500 UM146_RS00505 UM146_00480 UM146_RS00505 94531 94824 - RNA-binding protein RNA binding protein found associated to pre-50S subunit of the ribosome%3B putative role in ribosome assembly%3B necessary for optimal growth but not cell viability gene gene99 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00505 UM146_RS00510 UM146_00485 rrmJ rrmJ 94950 95579 + ribosomal RNA large subunit methyltransferase E Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit gene gene100 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00510 UM146_RS00515 UM146_00490 hflB hflB 95679 97613 + ATP-dependent zinc metalloprotease FtsH inner membrane metalloprotease%3B may be involved in degradation of aberrant cytoplasmic and membrane proteins gene gene101 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00515 UM146_RS00520 UM146_00495 folP folP 97703 98551 + dihydropteroate synthase catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7%2C8-dihydropteridine diphosphate and 4-aminobenzoate gene gene102 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00520 UM146_RS00525 UM146_00500 glmM glmM 98544 99881 + phosphoglucosamine mutase catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate gene gene103 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00525 UM146_RS00530 UM146_00505 secG secG 100109 100441 + protein-export membrane protein SecG gene gene104 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00530 UM146_RS00535 UM146_t23819 UM146_RS00535 100456 100542 + tRNA-Leu tRNA gene105 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00535 UM146_RS00540 UM146_00510 UM146_RS00540 101103 102620 + phosphate starvation-inducible protein PsiE gene gene106 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00540 UM146_RS00545 UM146_00515 UM146_RS00545 102628 103971 - argininosuccinate synthase catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis gene gene107 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00545 UM146_RS00550 UM146_t23821 UM146_RS00550 104319 104395 + tRNA-Met tRNA gene108 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00550 UM146_RS00555 UM146_00520 UM146_RS00555 104602 105054 + ribosome maturation factor RimP required for the maturation of the 30S ribosomal subunits gene gene109 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00555 UM146_RS00560 UM146_00525 nusA nusA 105082 106569 + transcription termination/antitermination protein NusA modifies transcription through interactions with RNA polymerase affecting elongation%2C readthrough%2C termination%2C and antitermination gene gene110 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00560 UM146_RS00565 UM146_00530 infB infB 106594 109266 + translation initiation factor IF-2 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex gene gene111 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00565 UM146_RS00570 UM146_00535 rbfA rbfA 109430 109831 + ribosome-binding factor A associates with free 30S ribosomal subunits%3B essential for efficient processing of 16S rRNA%3B in Escherichia coli rbfA is induced by cold shock gene gene112 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00570 UM146_RS00575 UM146_00540 truB truB 109831 110775 + tRNA pseudouridine synthase B catalyzes isomerization of specific uridines in RNA to pseudouridine%3B responsible for residues in T loops of many tRNAs gene gene113 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00575 UM146_RS00580 UM146_00545 UM146_RS00580 110924 111193 + 30S ribosomal protein S15 gene gene114 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00580 UM146_RS00585 UM146_00550 UM146_RS00585 111440 113575 + polyribonucleotide nucleotidyltransferase gene gene115 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00585 UM146_RS00590 UM146_00555 UM146_RS00590 113684 114568 + lipoprotein NlpI lipoprotein that appears to be involved in cell division%3B interacts with the periplasmic protease Prc and may be activated by protease processing gene gene116 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00590 UM146_RS00595 UM146_00560 UM146_RS00595 114748 116637 + DEAD/DEAH box family ATP-dependent RNA helicase participates in the assembly of the large subunit of the ribosome%3B plays a key role in optimal cell growth at low temperature and is required for normal cell division gene gene117 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00595 UM146_RS00600 UM146_RS00600 UM146_RS00600 116638 116775 - hypothetical protein gene gene118 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00600 UM146_RS00605 UM146_00565 UM146_RS00605 116791 118035 + tryptophan permease tryptophan transporter of high affinity gene gene119 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00605 UM146_RS00610 UM146_00570 UM146_RS00610 118153 119160 - hypothetical protein gene gene120 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00610 UM146_RS00615 UM146_00575 UM146_RS00615 119241 120119 - protease gene gene121 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00615 UM146_RS00620 UM146_00580 UM146_RS00620 120128 121123 - protease gene gene122 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00620 UM146_RS00625 UM146_00585 UM146_RS00625 121332 121856 + SCP-2 sterol transfer family protein gene gene123 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00625 UM146_RS00630 UM146_00590 UM146_RS00630 121850 122353 + N-acetyltransferase gene gene124 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00630 UM146_RS00635 UM146_00595 UM146_RS00635 122340 122642 - nuclease gene gene125 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00635 UM146_RS00640 UM146_00600 UM146_RS00640 122693 123136 + hypothetical protein gene gene126 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00640 UM146_RS00645 UM146_00605 UM146_RS00645 123116 123634 - general stress protein gene gene127 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00645 UM146_RS00650 UM146_00610 UM146_RS00650 123762 124397 + hypothetical protein gene gene128 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00650 UM146_RS00655 UM146_00615 UM146_RS00655 124470 125510 + membrane protein gene gene129 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00655 UM146_RS00660 UM146_00620 UM146_RS00660 125623 126198 - hypothetical protein gene gene130 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00660 UM146_RS00665 UM146_00625 UM146_RS00665 126208 126798 - DnaA initiator-associating protein DiaA Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein gene gene131 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00665 UM146_RS00670 UM146_00630 UM146_RS00670 126818 127213 - hypothetical protein gene gene132 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00670 UM146_RS00675 UM146_00635 UM146_RS00675 127171 129207 - penicillin-binding protein activator LpoA gene gene133 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00675 UM146_RS00680 UM146_00640 UM146_RS00680 129272 130135 + 16S rRNA (cytidine(1402)-2'-O)-methyltransferase gene gene134 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00680 UM146_RS00685 UM146_00645 UM146_RS00685 130185 130898 - galactosamine-6-phosphate isomerase gene gene135 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00685 UM146_RS00690 UM146_00650 UM146_RS00690 130953 131744 - PTS N-acetylgalactosamine transporter subunit IID catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IID with IIC forms the translocation channel%3B involved in N-acetylgalactosamine transport gene gene136 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00690 UM146_RS00695 UM146_00655 UM146_RS00695 131734 132537 - PTS N-acetylgalactosamine transporter subunit IIC catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3Bprotein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake%3B involved in N-acetylgalactosamine transport gene gene137 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00695 UM146_RS00700 UM146_00660 UM146_RS00700 132576 133052 - N-acetylgalactosamine-specific phosphotransferase enzyme IIB component 1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake%3B involved in N-acetylgalactosamine transport gene gene138 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00700 UM146_RS00705 UM146_00665 kbaY kbaY 133219 134079 - tagatose-1%2C6-bisphosphate aldolase catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1%2C6-bisphosphate%3B in enteric bacteria there are two D-tagatose 1%2C6-bisphosphate-specific aldolases: KbaY (also called AgaY)%2C involved in catabolism of N-acetyl-galactosamine and D-galactosamine%2C and GatY which is part of the galactitol catabolism pathway gene gene139 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00705 UM146_RS00710 UM146_00670 UM146_RS00710 134092 135246 - aldose isomerase gene gene140 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00710 UM146_RS00715 UM146_00675 UM146_RS00715 135595 136728 - N-acetylglucosamine-6-phosphate deacetylase gene gene141 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00715 UM146_RS00720 UM146_00680 UM146_RS00720 136725 137159 - PTS N-acetylgalactosamine transporter subunit IIA catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IID with IIC forms the translocation channel%3B involved in N-acetylgalactosamine transport gene gene142 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00720 UM146_RS00725 UM146_00685 UM146_RS00725 137177 138055 - PTS N-acetylgalactosamine transporter subunit IID catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IID with IIC forms the translocation channel%3B involved in N-acetylgalactosamine transport gene gene143 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00725 UM146_RS00730 UM146_00690 UM146_RS00730 138045 138824 - PTS N-acetylgalactosamine transporter subunit IIC catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake%3Binvolved in N-acetylgalactosamine transport gene gene144 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00730 UM146_RS00735 UM146_00695 UM146_RS00735 138835 139308 - PTS N-acetylgalactosamine transporter subunit IIB catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake%3B involved in N-acetylgalactosamine transport gene gene145 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00735 UM146_RS00740 UM146_00700 UM146_RS00740 139331 140611 - tagatose-1%2C6-bisphosphate aldolase with KbaY catalyzes the formation of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate from tagatose-1%2C6-bisphosphate%3B subunit Z may act as a chaperone for the Y subunit gene gene146 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00740 UM146_RS00745 UM146_00705 UM146_RS00745 140860 141684 + DeoR family transcriptional regulator transcriptional repressor for the agaZVWA and agaSYBCDI operons gene gene147 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00745 UM146_RS00750 UM146_00710 garD garD 141736 143307 - galactarate dehydrogenase catalyzes the formation of 5-dehydro-4-deoxy-D-glucarate from D-galactarate gene gene148 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00750 UM146_RS00755 UM146_00715 UM146_RS00755 143717 145015 + galactonate transporter gene gene149 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00755 UM146_RS00760 UM146_00720 UM146_RS00760 145031 145801 + 5-keto-4-deoxy-D-glucarate aldolase cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate gene gene150 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00760 UM146_RS00765 UM146_00725 garR garR 145831 146721 + 2-hydroxy-3-oxopropionate reductase catalyzes the reduction of tartronate semialdehyde to glycerate gene gene151 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00765 UM146_RS00770 UM146_00730 UM146_RS00770 146818 147963 + glycerate kinase gene gene152 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00770 UM146_RS00775 UM146_00735 UM146_RS00775 148937 149281 - transcriptional regulator participates in controlling the expression of several structural genes for the enzyme threonine dehydratase%3B TdcR activates the tdcABCDEFG operon gene gene153 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00775 UM146_RS00780 UM146_00740 UM146_RS00780 149471 150409 + transcriptional regulator regulates the tdcABCDEFG operon which is involved in amino acid degradation gene gene154 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00780 UM146_RS00785 UM146_00745 UM146_RS00785 150508 151497 + L-threonine dehydratase catabolic TdcB catalyzes the formation of 2-oxobutanoate from L-threonine%3B catabolic gene gene155 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00785 UM146_RS00790 UM146_00750 UM146_RS00790 151519 152850 + threonine/serine transporter TdcC gene gene156 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00790 UM146_RS00795 UM146_00755 UM146_RS00795 152876 154084 + propionate kinase catalyzes the formation of propanoyl phosphate from propanoate and ATP%3B TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism gene gene157 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00795 UM146_RS00800 UM146_00760 UM146_RS00800 154118 156412 + keto-acid formate acetyltransferase formate acetyltransferase%3B catalyzes the formation of formate and acetyl-CoA from pyruvate gene gene158 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00800 UM146_RS00805 UM146_00765 UM146_RS00805 156426 156815 + reactive intermediate/imine deaminase has endoribonuclease activity on mRNA gene gene159 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00805 UM146_RS00810 UM146_00770 UM146_RS00810 156887 158251 + L-serine dehydratase catalyzes the formation of pyruvate from serine gene gene160 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00810 UM146_RS00815 UM146_00775 UM146_RS00815 158525 159856 + transporter gene gene161 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00815 UM146_RS00820 UM146_00780 UM146_RS00820 159884 161194 + membrane protein gene gene162 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00820 UM146_RS00825 UM146_00785 UM146_RS00825 161326 161493 - hypothetical protein gene gene163 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00825 UM146_RS00830 UM146_00790 UM146_RS00830 161513 162214 - hypothetical protein gene gene164 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00830 UM146_RS00835 UM146_00795 UM146_RS00835 162319 163215 + LysR family transcriptional regulator gene gene165 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00835 UM146_RS00840 UM146_00800 UM146_RS00840 163249 163617 - membrane protein gene gene166 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00840 UM146_RS00845 UM146_00805 UM146_RS00845 163900 164886 - hypothetical protein gene gene167 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00845 UM146_RS00850 UM146_00810 UM146_RS00850 164956 165348 - membrane protein gene gene168 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00850 UM146_RS00855 UM146_00815 UM146_RS00855 165535 165834 - hypothetical protein gene gene169 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00855 UM146_RS00860 UM146_00820 UM146_RS00860 165824 166228 - hypothetical protein gene gene170 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00860 UM146_RS00865 UM146_00825 UM146_RS00865 166231 166536 - hypothetical protein gene gene171 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00865 UM146_RS00870 UM146_00830 UM146_RS00870 166574 166942 - hypothetical protein gene gene172 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00870 UM146_RS00875 UM146_00835 UM146_RS00875 167089 167472 - membrane protein gene gene173 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00875 UM146_RS00880 UM146_00840 UM146_RS00880 167476 168138 - hypothetical protein gene gene174 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00880 UM146_RS00885 UM146_00845 UM146_RS00885 168483 169259 - GntR family transcriptional regulator regulates the expression of uxuBA gene gene175 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00885 UM146_RS00890 UM146_00850 UM146_RS00890 169389 170687 - hexuronate transporter ExuT involved in the transport of aldohexuronates gene gene176 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00890 UM146_RS00895 UM146_00855 UM146_RS00895 171169 172581 + uronate isomerase catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate%3B functions in glucuronic and galacturonic metabolism gene gene177 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00895 UM146_RS00900 UM146_00860 UM146_RS00900 172596 174083 + altronate hydrolase gene gene178 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00900 UM146_RS00905 UM146_00865 UM146_RS00905 174166 174717 + membrane protein gene gene179 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00905 UM146_RS00910 UM146_00870 UM146_RS00910 174721 175965 - serine/threonine transporter SstT involved in the import of serine and threonine coupled with the import of sodium gene gene180 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00910 UM146_RS00915 UM146_00875 UM146_RS00915 176289 177254 - hypothetical protein gene gene181 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00915 UM146_RS00920 UM146_00880 UM146_RS00920 177536 178522 - oxidoreductase gene gene182 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00920 UM146_RS00925 UM146_00885 UM146_RS00925 178601 179293 - hypothetical protein gene gene183 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00925 UM146_RS00930 UM146_00890 UM146_RS00930 179370 179873 - hypothetical protein gene gene184 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00930 UM146_RS00935 UM146_00895 UM146_RS00935 179958 181094 + ribosomal RNA large subunit methyltransferase G gene gene185 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00935 UM146_RS00940 UM146_00900 UM146_RS00940 181212 183230 - 2%2C4-dienoyl-CoA reductase gene gene186 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00940 UM146_RS00945 UM146_00905 UM146_RS00945 183401 185752 - alpha-glucosidase gene gene187 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00945 UM146_RS00950 UM146_00910 UM146_RS00950 185769 186839 - hypothetical protein gene gene188 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00950 UM146_RS00955 UM146_00915 UM146_RS00955 186973 188406 - amino acid permease gene gene189 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00955 UM146_RS00960 UM146_00920 ebgC ebgC 188469 188918 - evolved beta-galactosidase subunit beta in Escherichia coli this is the second beta-galactosidase system gene gene190 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00960 UM146_RS00965 UM146_00925 ebgA ebgA 188915 192007 - beta-D-galactosidase subunit alpha in Escherichia coli this is the second beta-galactosidase system gene gene191 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00965 UM146_RS00970 UM146_00930 UM146_RS00970 192191 193174 - LacI family transcriptional regulator gene gene192 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00970 UM146_RS00975 UM146_00935 UM146_RS00975 193393 193725 + methionyl-tRNA synthetase gene gene193 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00975 UM146_RS00980 UM146_00940 UM146_RS00980 193767 195146 - putrescine aminotransferase catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate gene gene194 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00980 UM146_RS00985 UM146_00945 UM146_RS00985 195564 197084 + aerotaxis receptor gene gene195 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00985 UM146_RS00990 UM146_00950 UM146_RS00990 197276 197860 - transcriptional regulator gene gene196 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00990 UM146_RS00995 UM146_00955 UM146_RS00995 198137 198901 + FMN reductase gene gene197 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS00995 UM146_RS01000 UM146_t23823 UM146_RS01000 198955 199030 - tRNA-Met tRNA gene198 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01000 UM146_RS01005 UM146_00960 UM146_RS01005 199155 199661 + G/U mismatch DNA glycosylase gene gene199 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01005 UM146_RS01010 UM146_00965 UM146_RS01010 199740 201581 - RNA polymerase sigma factor RpoD sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B this is the primary sigma factor of bacteria gene gene200 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01010 UM146_RS01015 UM146_00970 dnaG dnaG 201776 203521 - DNA primase synthesizes RNA primers at the replication forks gene gene201 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01015 UM146_RS01020 UM146_00975 rpsU rpsU 203632 203847 - 30S ribosomal protein S21 a small basic protein that is one of the last in the subunit assembly%3B omission does not prevent assembly but the subunit is inactive%3B binds central domain of 16S rRNA gene gene202 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01020 UM146_RS01025 UM146_00980 UM146_RS01025 204085 205098 + tRNA N6-adenosine threonylcarbamoyltransferase universal genome maintenance protein%3B Kae1/Qri7/OSGEP/YgjD family protein%3B in Archaea%2C some Kae1 are found as fusion proteins similar to two distinct proteins in yeast that are involved in the KEOPS complex%3B kinase associated endopeptidase 1 (Kae1) and a serine/threonine protein kinase (Bud32)%3B in Pyrococcus Kae1 has atypical AP endonuclease activity and inhibits the kinase activity of Bud32%3B the protein is essential in Escherichia coli and Bacillus subtilis gene gene203 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01025 UM146_RS01030 UM146_00985 UM146_RS01030 205141 206604 - L-tartrate/succinate antiporter involved in the transport of citrate into the cell along with the export of succinate out of the cell gene gene204 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01030 UM146_RS01035 UM146_00990 UM146_RS01035 206652 207257 - L+-tartrate dehydratase subunit beta Involved in the tartrate degradation pathway gene gene205 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01035 UM146_RS01040 UM146_00995 UM146_RS01040 207254 208162 - tartrate dehydratase subunit alpha Involved in the tartrate degradation pathway gene gene206 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01040 UM146_RS01045 UM146_01000 UM146_RS01045 208372 209304 + transcriptional activator TtdR gene gene207 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01045 UM146_RS01050 UM146_01005 UM146_RS01050 209317 209934 - glycerol-3-phosphate acyltransferase involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis%3B functions with PlsX gene gene208 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01050 UM146_RS01055 UM146_01010 folB folB 210039 210407 + dihydroneopterin aldolase catalyzes the conversion of 7%2C8-dihydroneopterin to 6-hydroxymethyl-7%2C8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin gene gene209 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01055 UM146_RS01060 UM146_01015 UM146_RS01060 210498 211319 + undecaprenyl-diphosphatase BacA%3B phosphatase activity in Escherichia coli not kinase%3B involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell gene gene210 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01060 UM146_RS01065 UM146_01020 UM146_RS01065 211507 212745 - multifunctional CCA protein gene gene211 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01065 UM146_RS01070 UM146_01025 UM146_RS01070 212809 213429 - signal transduction protein gene gene212 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01070 UM146_RS01075 UM146_RS01075 UM146_RS01075 213469 213654 + hypothetical protein gene gene213 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01075 UM146_RS01080 UM146_01030 UM146_RS01080 213671 214972 + hypothetical protein gene gene214 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01080 UM146_RS01085 UM146_01035 UM146_RS01085 214995 217835 + glutamate--ammonia-ligase adenylyltransferase catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase%3B also catalyzes the reverse reaction - deadenylation%3B adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme gene gene215 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01085 UM146_RS01090 UM146_01040 UM146_RS01090 217883 219316 + bifunctional protein HldE catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D%2CD-heptose-1%2C7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D%2CD-heptose gene gene216 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01090 UM146_RS01095 UM146_RS01095 UM146_RS01095 219383 219634 - hypothetical protein gene gene217 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01095 UM146_RS01100 UM146_01045 UM146_RS01100 219735 221396 - membrane protein gene gene218 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01100 UM146_RS01105 UM146_01050 UM146_RS01105 221423 222052 - membrane protein gene gene219 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01105 UM146_RS01110 UM146_01055 UM146_RS01110 222321 222521 + glycogen synthase Involved in glycogen synthesis. May be involved in glycogen priming gene gene220 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01110 UM146_RS01115 UM146_01060 UM146_RS01115 222556 222855 - hypothetical protein gene gene221 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01115 UM146_RS01120 UM146_01065 ribB ribB 223229 223882 + 3%2C4-dihydroxy-2-butanone 4-phosphate synthase DHBP synthase%3B functions during riboflavin biosynthesis gene gene222 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01120 UM146_RS01125 UM146_01070 UM146_RS01125 223936 224985 - pilus protein gene gene223 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01125 UM146_RS01130 UM146_01075 UM146_RS01130 224982 225722 - fimbrial assembly protein PapD gene gene224 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01130 UM146_RS01135 UM146_01080 UM146_RS01135 225738 228260 - fimbrial outer membrane usher protein StdB gene gene225 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01135 UM146_RS01140 UM146_01085 UM146_RS01140 228347 228886 - fimbrial protein gene gene226 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01140 UM146_RS01145 UM146_01090 UM146_RS01145 229481 229651 + hypothetical protein gene gene227 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01145 UM146_RS01150 UM146_01095 UM146_RS01150 229713 230486 - zinc transporter ZupT gene gene228 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01150 UM146_RS01155 UM146_01100 UM146_RS01155 230629 231417 + LigB family dioxygenase seems to be involved in biofilm formation%3B in asymptomatic bacteriuria E. coli strains 83972 and VR50%2C the ygiD gene is upregulated during biofilm formation in urine gene gene229 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01155 UM146_RS01160 UM146_01105 UM146_RS01160 231463 232134 - protein-disulfide oxidoreductase DsbI gene gene230 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01160 UM146_RS01165 UM146_01110 UM146_RS01165 232149 232817 - thiol:disulfide interchange protein gene gene231 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01165 UM146_RS01170 UM146_01115 UM146_RS01170 232835 234631 - arylsulfate sulfotransferase gene gene232 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01170 UM146_RS01175 UM146_01120 UM146_RS01175 235116 236276 - hypothetical protein gene gene233 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01175 UM146_RS01180 UM146_01125 UM146_RS01180 236282 236953 - membrane protein gene gene234 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01180 UM146_RS01185 UM146_RS01185 UM146_RS01185 236841 237104 - hypothetical protein gene gene235 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01185 UM146_RS01190 UM146_01130 tolC tolC 237101 238582 - outer membrane channel protein trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules%3B functions with a number of efflux systems in the inner membrane to transport molecules out of the cell gene gene236 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01190 UM146_RS01195 UM146_01135 nudF nudF 238787 239416 + ADP-ribose pyrophosphatase ADP-sugar pyrophosphatase%3B catalyzes the formation of D-ribose 5-phosphate from ADP-ribose%3B can also act on ADP-mannose and ADP-glucose gene gene237 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01195 UM146_RS01200 UM146_01140 UM146_RS01200 239417 239839 + dehydrogenase gene gene238 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01200 UM146_RS01205 UM146_01145 UM146_RS01205 239864 240691 + 3'%2C5'-cyclic-nucleotide phosphodiesterase gene gene239 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01205 UM146_RS01210 UM146_01150 UM146_RS01210 240691 241272 + esterase Displays esterase activity toward palmitoyl-CoA and pNP-butyrate gene gene240 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01210 UM146_RS01215 UM146_01155 UM146_RS01215 241301 243193 + DNA topoisomerase IV subunit B decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling gene gene241 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01215 UM146_RS01220 UM146_01160 UM146_RS01220 243257 245398 - TonB-dependent receptor gene gene242 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01220 UM146_RS01225 UM146_01165 UM146_RS01225 245772 246581 + ABC transporter gene gene243 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01225 UM146_RS01230 UM146_01170 UM146_RS01230 246578 247561 + heme ABC transporter gene gene244 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01230 UM146_RS01235 UM146_01175 UM146_RS01235 247558 248607 + iron ABC transporter gene gene245 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01235 UM146_RS01240 UM146_01180 UM146_RS01240 248618 249565 + protein translocase component YidC gene gene246 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01240 UM146_RS01245 UM146_01185 UM146_RS01245 249562 250449 + RpiR family transcriptional regulator gene gene247 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01245 UM146_RS01250 UM146_01190 UM146_RS01250 250494 250808 - quinol monooxygenase catalyzes the oxidation of menadiol to menadione gene gene248 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01250 UM146_RS01255 UM146_01195 UM146_RS01255 250839 251420 - modulator of drug activity B involved in drug resistance gene gene249 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01255 UM146_RS01260 UM146_01200 UM146_RS01260 251670 252149 + hypothetical protein gene gene250 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01260 UM146_RS01265 UM146_01205 UM146_RS01265 252152 252862 + hypothetical protein gene gene251 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01265 UM146_RS01270 UM146_01210 UM146_RS01270 252869 253201 + membrane protein gene gene252 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01270 UM146_RS01275 UM146_01215 UM146_RS01275 253247 254596 - two-component system sensor histidine kinase gene gene253 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01275 UM146_RS01280 UM146_01220 UM146_RS01280 254593 255252 - two-component system response regulator response regulator in two-component regulatory system with QseC%3B regulates FlhCD which is the master regulator for flagella and motility genes gene gene254 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01280 UM146_RS01285 UM146_01225 UM146_RS01285 255237 255404 - transcriptional regulator gene gene255 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01285 UM146_RS01290 UM146_01230 UM146_RS01290 255403 255795 + hypothetical protein gene gene256 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01290 UM146_RS01295 UM146_01235 UM146_RS01295 255848 256330 + transcriptional regulator gene gene257 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01295 UM146_RS01300 UM146_01240 UM146_RS01300 256439 258046 + ABC transporter substrate-binding protein gene gene258 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01300 UM146_RS01305 UM146_01245 UM146_RS01305 258184 260442 + DNA topoisomerase IV subunit A decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling gene gene259 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01305 UM146_RS01310 UM146_01250 UM146_RS01310 260677 261414 + 1-acyl-sn-glycerol-3-phosphate acyltransferase catalyzes the formation of 1%2C2-diacyl-sn-glycerol 3-phosphate from 1-acyl-sn-glycerol 3-phosphate using either acyl-CoA or acyl-ACP gene gene260 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01310 UM146_RS01315 UM146_01255 UM146_RS01315 261489 262901 + cell division protein FtsI septal ring component that protects the divisome from stress gene gene261 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01315 UM146_RS01320 UM146_01260 UM146_RS01320 262972 264276 - membrane protein gene gene262 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01320 UM146_RS01325 UM146_01265 UM146_RS01325 264287 264769 - C4-dicarboxylate ABC transporter permease gene gene263 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01325 UM146_RS01330 UM146_01270 UM146_RS01330 264811 265794 - C4-dicarboxylate ABC transporter substrate-binding protein gene gene264 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01330 UM146_RS01335 UM146_01275 UM146_RS01335 265867 266877 - ureidoglycolate dehydrogenase catalyzes the formation of oxalurate from ureidoglycolate gene gene265 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01335 UM146_RS01340 UM146_01280 UM146_RS01340 266888 267904 - galactonate oxidoreductase gene gene266 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01340 UM146_RS01345 UM146_01285 UM146_RS01345 267901 269373 - fructuronate reductase gene gene267 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01345 UM146_RS01350 UM146_01290 UM146_RS01350 269696 270445 - GntR family transcriptional regulator gene gene268 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01350 UM146_RS01355 UM146_01295 UM146_RS01355 270697 272916 + radical SAM protein gene gene269 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01355 UM146_RS01360 UM146_01300 UM146_RS01360 272958 273215 - membrane protein gene gene270 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01360 UM146_RS01365 UM146_01305 UM146_RS01365 273266 274192 - hypothetical protein gene gene271 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01365 UM146_RS01370 UM146_01310 dkgA dkgA 274392 275219 - 2%2C5-diketo-D-gluconate reductase A methylglyoxal reductase/beta-keto ester reductase%3B catalyzes the reduction of 2%2C5-diketo-D-gluconic acid to 2-keto-L-gulonic acid%3B also catalyzes the reduction of methylglyoxal%2C ethyl-2-methylacetoacetate and ethyl-acetoacetate gene gene272 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01370 UM146_RS01375 UM146_01315 UM146_RS01375 275324 276487 - alcohol dehydrogenase gene gene273 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01375 UM146_RS01380 UM146_RS01380 UM146_RS01380 276538 276684 + hypothetical protein gene gene274 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01380 UM146_RS01385 UM146_01320 UM146_RS01385 276681 277580 + AraC family transcriptional regulator gene gene275 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01385 UM146_RS01390 UM146_01325 UM146_RS01390 277620 278279 - hypothetical protein gene gene276 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01390 UM146_RS01395 UM146_01330 UM146_RS01395 278419 279606 - cystathionine beta-lyase catalyzes the formation of L-homocysteine from cystathionine gene gene277 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01395 UM146_RS01400 UM146_RS01400 UM146_RS01400 279728 279865 + membrane protein gene gene278 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01400 UM146_RS01405 UM146_01335 UM146_RS01405 279858 280592 + biopolymer transporter ExbB membrane spanning protein in TonB-ExbB-ExbD complex%3B involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell gene gene279 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01405 UM146_RS01410 UM146_01340 UM146_RS01410 280599 281024 + biopolymer transporter ExbD membrane spanning protein in TonB-ExbB-ExbD complex%3B involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell gene gene280 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01410 UM146_RS01415 UM146_01345 UM146_RS01415 281063 281947 - oxidoreductase gene gene281 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01415 UM146_RS01420 UM146_01350 UM146_RS01420 282138 282632 + hypothetical protein gene gene282 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01420 UM146_RS01425 UM146_01355 UM146_RS01425 282672 283712 - glyceraldehyde 3-phosphate reductase gene gene283 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01425 UM146_RS01430 UM146_01360 UM146_RS01430 283869 284756 + dienelactone hydrolase gene gene284 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01430 UM146_RS01435 UM146_01365 UM146_RS01435 284875 285162 + hypothetical protein gene gene285 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01435 UM146_RS01440 UM146_RS01440 UM146_RS01440 285159 285344 + hypothetical protein gene gene286 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01440 UM146_RS01445 UM146_01370 UM146_RS01445 285351 286469 + hydrogenase-2 small chain involved in hydrogen uptake gene gene287 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01445 UM146_RS01450 UM146_01375 UM146_RS01450 286472 287458 + hydrogenase Fe-S ferrodoxin type component%3B participates in the periplasmic electron-transferring activity of hydrogenase 2 gene gene288 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01450 UM146_RS01455 UM146_01380 UM146_RS01455 287448 288626 + Ni/Fe-hydrogenase b-type cytochrome subunit HybB%3B cytochrome b subunit of the hydrogenase 2 enzyme%2C composed of HybA%2C B%2C C%2C and O subunits gene gene289 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01455 UM146_RS01460 UM146_01385 UM146_RS01460 288623 290326 + hydrogenase-2 large chain involved in hydrogen uptake gene gene290 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01460 UM146_RS01465 UM146_01390 hybD hybD 290326 290820 + hydrogenase 2 maturation endopeptidase protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC) gene gene291 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01465 UM146_RS01470 UM146_01395 UM146_RS01470 290813 291301 + hydrogenase gene gene292 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01470 UM146_RS01475 UM146_01400 hypA hypA 291294 291635 + hydrogenase nickel incorporation protein HybF plays a role in hydrogenase nickel cofactor insertion gene gene293 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01475 UM146_RS01480 UM146_01405 UM146_RS01480 291648 291896 + hydrogenase-2 operon protein HybG gene gene294 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01480 UM146_RS01485 UM146_01410 UM146_RS01485 292029 292895 - S-transferase YghU%3B B2989%3B one of eight putative glutathione transferase proteins from E. coli gene gene295 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01485 UM146_RS01490 UM146_01415 UM146_RS01490 293100 294959 + bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase catalyzes the formation of glutathionylspermidine from glutathione and spermidine%3B also catalyzes the reverse reaction gene gene296 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01490 UM146_RS01495 UM146_01420 UM146_RS01495 295251 296750 + low-affinity inorganic phosphate transporter 2 involved in the transport of inorganic phosphate gene gene297 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01495 UM146_RS01500 UM146_01425 UM146_RS01500 296799 297491 - ATP-binding protein gene gene298 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01500 UM146_RS01505 UM146_01430 UM146_RS01505 297681 298379 + hypothetical protein gene gene299 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01505 UM146_RS01510 UM146_01435 UM146_RS01510 298411 299169 + hypothetical protein gene gene300 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01510 UM146_RS01515 UM146_01440 UM146_RS01515 299215 300564 + membrane protein gene gene301 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01515 UM146_RS01520 UM146_01445 UM146_RS01520 300564 301400 + hypothetical protein gene gene302 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01520 UM146_RS01525 UM146_01450 UM146_RS01525 301400 301960 + hypothetical protein gene gene303 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01525 UM146_RS01530 UM146_01455 UM146_RS01530 301991 303061 + LPS export ABC transporter permease LptF gene gene304 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01530 UM146_RS01535 UM146_01460 UM146_RS01535 303058 304137 + LPS export ABC transporter permease LptG gene gene305 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01535 UM146_RS01540 UM146_RS01540 UM146_RS01540 304172 305343 - 8-amino-7-oxononanoate synthase gene gene306 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01540 UM146_RS01545 UM146_01475 UM146_RS01545 305343 305591 - hypothetical protein gene gene307 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01545 UM146_RS01550 UM146_01480 UM146_RS01550 305623 306537 - short-chain dehydrogenase gene gene308 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01550 UM146_RS01555 UM146_01485 UM146_RS01555 306534 308225 - acyl-CoA synthetase activates fatty acids by binding to coenzyme A gene gene309 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01555 UM146_RS01560 UM146_01490 UM146_RS01560 308629 309771 + DNA-binding protein gene gene310 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01560 UM146_RS01565 UM146_01495 UM146_RS01565 309778 310542 - GntR family transcriptional regulator gene gene311 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01565 UM146_RS01570 UM146_01500 UM146_RS01570 310793 312292 + FAD-binding protein gene gene312 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01570 UM146_RS01575 UM146_01505 glcE glcE 312292 313344 + FAD-binding protein gene gene313 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01575 UM146_RS01580 UM146_01510 glcF glcF 313355 314578 + glycolate oxidase gene gene314 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01580 UM146_RS01585 UM146_01515 UM146_RS01585 314583 314987 + protein GlcG gene gene315 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01585 UM146_RS01590 UM146_01520 UM146_RS01590 315009 317180 + malate synthase G gene gene316 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01590 UM146_RS01595 UM146_01525 UM146_RS01595 317536 319218 + glycolate permease GlcA gene gene317 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01595 UM146_RS01600 UM146_RS01600 UM146_RS01600 319246 319551 - hypothetical protein gene gene318 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01600 UM146_RS01605 UM146_01530 UM146_RS01605 319702 324264 + hypothetical protein gene gene319 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01605 UM146_RS01610 UM146_01535 UM146_RS01610 324428 325237 + peptidase A24 gene gene320 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01610 UM146_RS01615 UM146_01540 UM146_RS01615 325303 325713 + hypothetical protein gene gene321 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01615 UM146_RS01620 UM146_01545 UM146_RS01620 325731 326690 + type II secretion system protein GspC part of the general (type II) secretion pathway (GSP)%2C a signal sequence-dependent process responsible for protein export%3B involved in trans-location of exoproteins from the cytoplasm to the periplasm gene gene322 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01620 UM146_RS01625 UM146_01550 UM146_RS01625 326720 328780 + type II secretion system protein GspD gene gene323 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01625 UM146_RS01630 UM146_01555 UM146_RS01630 328780 330273 + type II secretion system protein GspE gene gene324 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01630 UM146_RS01635 UM146_01560 UM146_RS01635 330273 331496 + type II secretion system protein GspF gene gene325 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01635 UM146_RS01640 UM146_01565 UM146_RS01640 331513 331968 + type II secretion system protein GspG gene gene326 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01640 UM146_RS01645 UM146_01570 UM146_RS01645 331972 332535 + type II secretion system protein GspH gene gene327 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01645 UM146_RS01650 UM146_01575 UM146_RS01650 332532 332903 + type II secretion system protein GspI gene gene328 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01650 UM146_RS01655 UM146_01580 UM146_RS01655 332900 333505 + type II secretion system protein GspJ gene gene329 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01655 UM146_RS01660 UM146_01585 UM146_RS01660 333502 334479 + type II secretion system protein gene gene330 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01660 UM146_RS01665 UM146_01590 UM146_RS01665 334476 335654 + type II secretion system protein GspL similar to general secretory pathway protein L gene gene331 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01665 UM146_RS01670 UM146_01595 UM146_RS01670 335656 336192 + general secretion pathway protein gene gene332 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01670 UM146_RS01675 UM146_01600 UM146_RS01675 337250 338026 + polysialic acid transporter KpsM gene gene333 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01675 UM146_RS01680 UM146_01605 UM146_RS01680 338023 338682 + polysialic acid transport ATP-binding protein KpsT gene gene334 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01680 UM146_RS01685 UM146_01610 UM146_RS01685 338732 339355 + shikimate 5-dehydrogenase gene gene335 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01685 UM146_RS01690 UM146_RS01690 UM146_RS01690 339352 340391 + N-acetyl neuramic acid synthetase NeuB gene gene336 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01690 UM146_RS01695 UM146_01625 UM146_RS01695 340391 341647 + N-acylneuraminate cytidylyltransferase gene gene337 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01695 UM146_RS01700 UM146_01630 UM146_RS01700 341644 342819 + polysialic acid biosynthesis protein P7 gene gene338 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01700 UM146_RS01705 UM146_01635 UM146_RS01705 342812 343903 + hypothetical protein gene gene339 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01705 UM146_RS01710 UM146_01640 UM146_RS01710 343949 345178 + poly-alpha-2%2C8 sialosyl sialyltransferase gene gene340 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01710 UM146_RS01715 UM146_01645 UM146_RS01715 345328 346533 - capsular polysaccharide biosynthesis protein gene gene341 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01715 UM146_RS01720 UM146_01650 UM146_RS01720 346568 348595 - capsule polysaccharide transporter gene gene342 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01720 UM146_RS01725 UM146_01655 UM146_RS01725 348592 349332 - 3-deoxy-manno-octulosonate cytidylyltransferase gene gene343 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01725 UM146_RS01730 UM146_01660 UM146_RS01730 349342 351018 - polysialic acid transporter KpsD gene gene344 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01730 UM146_RS01735 UM146_01665 UM146_RS01735 351042 352190 - capsule polysaccharide export inner-membrane protein KpsE gene gene345 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01735 UM146_RS01740 UM146_01670 UM146_RS01740 352262 353245 - arabinose 5-phosphate isomerase gene gene346 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01740 UM146_RS01745 UM146_01675 UM146_RS01745 354055 354210 - transposase gene gene347 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01745 UM146_RS01750 UM146_t23825 UM146_RS01750 354435 354510 - tRNA-Phe tRNA gene348 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01750 UM146_RS01755 UM146_01680 UM146_RS01755 354616 355323 - membrane protein gene gene349 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01755 UM146_RS01760 UM146_01685 UM146_RS01760 355722 357857 + ornithine decarboxylase gene gene350 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01760 UM146_RS01765 UM146_01690 UM146_RS01765 357906 359162 - nucleoside permease gene gene351 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01765 UM146_RS01770 UM146_01695 mltC mltC 359364 360443 - murein transglycosylase Murein hydrolase C%3B membrane-bound%3B lytic%3B catalyzes the cleavage of the beta-1%2C4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues gene gene352 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01770 UM146_RS01775 UM146_01700 UM146_RS01775 360508 360783 - Fe(2+)-trafficking protein protects iron-sulfur proteins against oxidative damage gene gene353 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01775 UM146_RS01780 UM146_01705 UM146_RS01780 360811 361863 - A/G-specific adenine glycosylase gene gene354 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01780 UM146_RS01785 UM146_01710 trmB trmB 362024 362743 + tRNA (guanine-N(7)-)-methyltransferase tRNA (guanine-N(7)-)-methyltransferase%3B catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine gene gene355 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01785 UM146_RS01790 UM146_01715 UM146_RS01790 362743 363069 + hypothetical protein gene gene356 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01790 UM146_RS01795 UM146_01720 UM146_RS01795 363092 363232 + hypothetical protein gene gene357 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01795 UM146_RS01800 UM146_01725 UM146_RS01800 363253 363972 + hypothetical protein gene gene358 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01800 UM146_RS01805 UM146_01730 ansB ansB 364148 365194 + L-asparaginase catalyzes the formation of aspartate from asparagine%2C periplasmic%3B regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis gene gene359 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01805 UM146_RS01810 UM146_01735 UM146_RS01810 365311 366318 + hypothetical protein gene gene360 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01810 UM146_RS01815 UM146_01740 UM146_RS01815 366387 367523 - HemN family oxidoreductase gene gene361 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01815 UM146_RS01820 UM146_01745 UM146_RS01820 367516 368109 - non-canonical purine NTP pyrophosphatase HAM1-like protein%3B Rec-dependent growth%3B RgdB%3B yggV%3B it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine gene gene362 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01820 UM146_RS01825 UM146_01750 UM146_RS01825 368117 368407 - hypothetical protein gene gene363 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01825 UM146_RS01830 UM146_01755 UM146_RS01830 368404 368970 - hypothetical protein gene gene364 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01830 UM146_RS01835 UM146_01760 UM146_RS01835 368988 369692 - YggS family pyridoxal phosphate enzyme gene gene365 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01835 UM146_RS01840 UM146_01765 UM146_RS01840 369809 370690 + twitching motility protein gene gene366 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01840 UM146_RS01845 UM146_01770 UM146_RS01845 370864 371280 - Holliday junction DNA helicase similar to RuvC resolvase with substantial differences%3B NMR structural information suggests this protein is monomeric%3B unknown cellular function gene gene367 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01845 UM146_RS01850 UM146_01775 UM146_RS01850 371280 371843 - hypothetical protein gene gene368 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01850 UM146_RS01855 UM146_01780 UM146_RS01855 371952 372902 - glutathione synthetase catalyzes the second step in the glutathione biosynthesis pathway%2C where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine %3D ADP + phosphate + glutathione gene gene369 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01855 UM146_RS01860 UM146_01785 UM146_RS01860 372915 373646 - ribosomal RNA small subunit methyltransferase E in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA%3B cells lacking this function can grow%2C but are outcompeted by wild-type%3B SAM-dependent m(3)U1498 methyltransferase gene gene370 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01860 UM146_RS01865 UM146_01790 UM146_RS01865 373726 374433 - endonuclease gene gene371 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01865 UM146_RS01870 UM146_01795 UM146_RS01870 374528 375025 - protein SprT gene gene372 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01870 UM146_RS01875 UM146_01800 UM146_RS01875 375102 376496 - D-galactose transporter gene gene373 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01875 UM146_RS01880 UM146_01805 UM146_RS01880 376933 378087 - S-adenosylmethionine synthase catalyzes the formation of S-adenosylmethionine from methionine and ATP%3B methionine adenosyltransferase gene gene374 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01880 UM146_RS01885 UM146_01810 UM146_RS01885 378143 378394 + membrane protein gene gene375 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01885 UM146_RS01890 UM146_RS01890 UM146_RS01890 378391 378606 - hypothetical protein gene gene376 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01890 UM146_RS01895 UM146_01815 UM146_RS01895 378742 378873 + hypothetical protein gene gene377 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01895 UM146_RS01900 UM146_01820 UM146_RS01900 378882 380858 + biosynthetic arginine decarboxylase catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis gene gene378 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01900 UM146_RS01905 UM146_01825 UM146_RS01905 381004 381735 + membrane protein gene gene379 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01905 UM146_RS01910 UM146_01830 UM146_RS01910 381871 382791 + agmatinase catalyzes the formation of putrescine from agmatine gene gene380 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01910 UM146_RS01915 UM146_01835 UM146_RS01915 382995 383753 - metalloprotease gene gene381 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01915 UM146_RS01920 UM146_01840 UM146_RS01920 384031 386022 + transketolase catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate%3B can transfer ketol groups between several groups%3B in Escherichia coli there are two tkt genes%2C tktA expressed during exponential growth and the tktB during stationary phase gene gene382 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01920 UM146_RS01925 UM146_01845 UM146_RS01925 386242 387150 - SPFH domain protein gene gene383 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01925 UM146_RS01930 UM146_01850 cmtB cmtB 387527 387970 + PTS mannitol transporter subunit IIA TolM%3B with CmtA (IIBC)%2C CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system%2C which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli%3B cytoplasmic protein gene gene384 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01930 UM146_RS01935 UM146_01855 UM146_RS01935 387998 389386 + PTS mannitol cryptic EIICB component CmtA with CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system%2C which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli%3B cytoplasmic protein gene gene385 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01935 UM146_RS01940 UM146_01860 UM146_RS01940 389401 390678 + L-sorbose 1-phosphate reductase gene gene386 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01940 UM146_RS01945 UM146_01865 UM146_RS01945 390675 390863 + fructose 1%2C6-bisphosphatase gene gene387 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01945 UM146_RS01950 UM146_01875 UM146_RS01950 391012 391521 + mannitol repressor gene gene388 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01950 UM146_RS01955 UM146_01880 UM146_RS01955 391518 392231 + nucleoside triphosphate hydrolase gene gene389 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01955 UM146_RS01960 UM146_01885 UM146_RS01960 392203 392880 - ABC transporter ATP-binding protein gene gene390 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01960 UM146_RS01965 UM146_01890 UM146_RS01965 392874 393551 - cobalt ABC transporter ATP-binding protein gene gene391 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01965 UM146_RS01970 UM146_01895 UM146_RS01970 393539 394246 - cobalt ABC transporter permease gene gene392 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01970 UM146_RS01975 UM146_01900 UM146_RS01975 394247 394825 - membrane protein gene gene393 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01975 UM146_RS01980 UM146_01905 UM146_RS01980 394848 395279 - DNA-binding protein gene gene394 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01980 UM146_RS01985 UM146_01910 gapA gapA 395651 396670 + D-erythrose-4-phosphate dehydrogenase required for glycolysis%3B catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate gene gene395 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01985 UM146_RS01990 UM146_01915 UM146_RS01990 396720 397883 + phosphoglycerate kinase gene gene396 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01990 UM146_RS01995 UM146_01920 UM146_RS01995 398098 399177 + fructose-bisphosphate aldolase catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1%2C6%2C bisphosphate gene gene397 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS01995 UM146_RS02000 UM146_01925 UM146_RS02000 399368 400228 + mechanosensitive ion channel protein MscS participates in the regulation of osmotic pressure changes within the cel gene gene398 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02000 UM146_RS02005 UM146_01930 UM146_RS02005 400409 400999 + arginine exporter protein Involved in the export of arginine gene gene399 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02005 UM146_RS02010 UM146_01935 UM146_RS02010 401092 401832 + oxidative stress defense protein gene gene400 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02010 UM146_RS02015 UM146_01940 UM146_RS02015 401990 402886 + LysR family transcriptional regulator gene gene401 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02015 UM146_RS02020 UM146_01945 UM146_RS02020 403060 403938 - methylmalonyl-CoA mutase gene gene402 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02020 UM146_RS02025 UM146_01950 UM146_RS02025 404141 405034 - chromosome initiation inhibitor specific inhibitor of chromosomal initiation of replication in vitro%3B binds the three 13-mers in the origin (oriC) to block initiation of replication%3B also controls genes involved in arginine transport gene gene403 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02025 UM146_RS02030 UM146_01955 UM146_RS02030 405175 405405 + hypothetical protein gene gene404 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02030 UM146_RS02035 UM146_01960 UM146_RS02035 405461 406120 + ribose-5-phosphate isomerase A catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway gene gene405 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02035 UM146_RS02040 UM146_01965 UM146_RS02040 406376 407608 + D-3-phosphoglycerate dehydrogenase catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis%3B can also reduce alpha ketoglutarate to form 2-hydroxyglutarate gene gene406 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02040 UM146_RS02045 UM146_01970 UM146_RS02045 407998 408600 - 5-formyltetrahydrofolate cyclo-ligase ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms%3B unknown function gene gene407 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02045 UM146_RS02050 UM146_01975 UM146_RS02050 408846 409175 - cell division protein ZapA gene gene408 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02050 UM146_RS02055 UM146_01980 UM146_RS02055 409337 409921 + hypothetical protein the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers%3B function unknown gene gene409 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02055 UM146_RS02060 UM146_01985 UM146_RS02060 409946 411271 + proline aminopeptidase P II exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue%3B substrate can be as short as a dipeptide gene gene410 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02060 UM146_RS02065 UM146_01990 UM146_RS02065 411268 412446 + 2-octaprenyl-6-methoxyphenyl hydroxylase Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1%2C4-benzoquinone gene gene411 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02065 UM146_RS02070 UM146_01995 UM146_RS02070 412469 413671 + 2-octaprenyl-6-methoxyphenyl hydroxylase gene gene412 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02070 UM146_RS02075 UM146_02000 gcvT gcvT 414119 415213 + aminomethyltransferase catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate%2C causing the release of ammonia and the generation of reduced GcvH protein gene gene413 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02075 UM146_RS02080 UM146_02005 UM146_RS02080 415237 415626 + glycine cleavage system protein H part of multienzyme complex composed of H%2C L%2C P%2C and T proteins which catalyzes oxidation of glycine to yield carbon dioxide%2C ammonia%2C 5%2C10-CH2-H4folate and a reduced pyridine nucleotide%3B protein H is involved in transfer of methylamine group from the P to T protein%3B covalently bound to a lipoyl cofactor gene gene414 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02080 UM146_RS02085 UM146_02010 UM146_RS02085 415744 418617 + glycine dehydrogenase (decarboxylating) acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine gene gene415 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02085 UM146_RS02090 UM146_02015 UM146_RS02090 418783 420261 - 6-phospho-beta-glucosidase gene gene416 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02090 UM146_RS02095 UM146_02020 UM146_RS02095 420260 420571 + hypothetical protein gene gene417 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02095 UM146_RS02100 UM146_02025 UM146_RS02100 420735 421394 + hemolysin gene gene418 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02100 UM146_RS02105 UM146_02030 ygfZ ygfZ 421471 422451 - tRNA-modifying protein YgfZ physiological role is not clear%3B not essential for growth but mutants grow poorly%3B mutations suppress hda null mutations%3B may be involved in regulation of ATP-DnaA levels%3B may also be involved in regulation of tRNA modifications%3B can bind folic acid and tetrahydrofolate%3B forms a three domain ring-like structure with a central channel%3B structurally similar to DMGO protein from A. globiformis%3B shows sequence similarity to yeast CAF17 transcriptional regulato%3B Hda supressor gene gene419 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02105 UM146_RS02110 UM146_02035 UM146_RS02110 422694 422960 + antitoxin CptB gene gene420 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02110 UM146_RS02115 UM146_02040 UM146_RS02115 422941 423348 + membrane protein gene gene421 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02115 UM146_RS02120 UM146_02045 UM146_RS02120 423388 423909 - flavodoxin-2 An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic gene gene422 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02120 UM146_RS02125 UM146_02050 xerD xerD 424021 424917 + tyrosine recombinase XerD site-specific tyrosine recombinase which cuts and rejoins DNA molecules%3B binds cooperatively to specific DNA consensus sites%3B forms a heterotetrameric complex with XerC%3B XerCD exhibit similar sequences%3B essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation%3B XerD specifically exchanges the bottom strands%3B cell division protein FtsK may regulate the XerCD complex%3B enzyme from Streptococcus group has unusual active site motifs gene gene423 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02125 UM146_RS02130 UM146_02055 UM146_RS02130 424942 425652 + thiol:disulfide interchange protein DsbC DsbC%3B periplasmic protein with protein disulfide isomerase activity%3B this protein also shows disulfide oxidoreductase activity gene gene424 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02130 UM146_RS02135 UM146_02060 UM146_RS02135 425658 427391 + ssDNA exonuclease RecJ 5'-3' single-stranded-DNA-specific exonuclease gene gene425 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02135 UM146_RS02140 UM146_02065 UM146_RS02140 427699 428580 + peptide chain release factor 2 catalyzes the release of newly synthesized polypeptide chains at the stop codons UAA and UGA gene gene426 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02140 UM146_RS02145 UM146_02070 lysS lysS 428590 430107 + lysine--tRNA ligase class II%3B LysRS2%3B catalyzes a two-step reaction%2C first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B in Methanosarcina barkeri%2C LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 gene gene427 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02145 UM146_RS02150 UM146_02075 UM146_RS02150 430149 430697 - isopentenyl-diphosphate delta isomerase catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate gene gene428 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02150 UM146_RS02155 UM146_02080 UM146_RS02155 430820 430945 - hypothetical protein gene gene429 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02155 UM146_RS02160 UM146_02085 UM146_RS02160 430947 432395 - purine permease gene gene430 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02160 UM146_RS02165 UM146_RS02165 UM146_RS02165 432340 432528 - hypothetical protein gene gene431 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02165 UM146_RS02170 UM146_02090 UM146_RS02170 432831 434750 + oxidoreductase Fe-S-binding subunit unknown function%3B in E. coli the aegA gene is regulated by Fnr%2C NarXL%2C and NarQ (but not ArcA)%2C induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) gene gene432 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02170 UM146_RS02175 UM146_02095 UM146_RS02175 434750 435238 + effector protein gene gene433 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02175 UM146_RS02180 UM146_02100 UM146_RS02180 435274 436641 - transporter gene gene434 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02180 UM146_RS02185 UM146_02105 UM146_RS02185 436677 437993 - guanine deaminase Catalyzes the deamination of guanine gene gene435 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02185 UM146_RS02190 UM146_02110 UM146_RS02190 438011 439411 - xanthine permease XanQ high-affinity transporter for xanthine gene gene436 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02190 UM146_RS02195 UM146_02115 UM146_RS02195 439576 442446 - hypoxanthine oxidase gene gene437 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02195 UM146_RS02200 UM146_02120 UM146_RS02200 442443 443222 - oxidoreductase gene gene438 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02200 UM146_RS02205 UM146_02125 UM146_RS02205 443273 444601 - chlorohydrolase/aminohydrolase in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS gene gene439 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02205 UM146_RS02210 UM146_02130 UM146_RS02210 444604 447702 - selenate reductase with YgfM and YgfN forms a selenate reductase%2C which seems to catalyze the reduction of selenate to selenite%3B YgfK mutants are unable to reduce selenate%3B involved in purine salvage process%3B seems to act as an oxidoreductase%2C but sequence similarity suggests it is a dihydrothymine dehydrogenase gene gene440 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02210 UM146_RS02215 UM146_02135 UM146_RS02215 448024 448602 - hypothetical protein gene gene441 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02215 UM146_RS02220 UM146_02140 UM146_RS02220 448706 449476 + hypothetical protein gene gene442 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02220 UM146_RS02225 UM146_02145 UM146_RS02225 449524 451149 + hypothetical protein gene gene443 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02225 UM146_RS02230 UM146_02150 UM146_RS02230 451190 452122 - carbamate kinase gene gene444 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02230 UM146_RS02235 UM146_02155 UM146_RS02235 452170 453555 - D-phenylhydantoinase catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position gene gene445 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02235 UM146_RS02240 UM146_02160 UM146_RS02240 453608 454819 - peptidase Zn-dependent extracellular dipeptidase%3B similar to succinyl-diaminopimelate desuccinylases gene gene446 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02240 UM146_RS02245 UM146_02165 UM146_RS02245 454877 456073 - diaminopropionate ammonia-lyase catalyzes the formation of pyruvate from 2%2C3-diaminopropionate gene gene447 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02245 UM146_RS02250 UM146_02170 UM146_RS02250 456131 457318 - ornithine carbamoyltransferase gene gene448 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02250 UM146_RS02255 UM146_02175 UM146_RS02255 457797 459575 + Fis family transcriptional regulator gene gene449 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02255 UM146_RS02260 UM146_02180 UM146_RS02260 459615 460094 - xanthine dehydrogenase subunit C iron-sulfur-binding subunit%3B with XdhA and XdhB participates in purine salvage gene gene450 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02260 UM146_RS02265 UM146_02185 UM146_RS02265 460091 460969 - xanthine dehydrogenase subunit B FAD-binding subunit%3B with XdhA and XdhC participates in purine salvage gene gene451 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02265 UM146_RS02270 UM146_02190 UM146_RS02270 460980 463277 - xanthine dehydrogenase subunit A molybdenum cofactor-binding protein%3B participates in purine salvage gene gene452 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02270 UM146_RS02275 UM146_02195 UM146_RS02275 463691 464446 + lipoprotein gene gene453 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02275 UM146_RS02280 UM146_t23827 UM146_RS02280 464525 464598 + tRNA-Gly tRNA gene454 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02280 UM146_RS02285 UM146_02200 UM146_RS02285 464915 466144 - transporter gene gene455 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02285 UM146_RS02290 UM146_02205 UM146_RS02290 466399 467580 + acetyl-CoA acetyltransferase gene gene456 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02290 UM146_RS02295 UM146_02210 UM146_RS02295 467867 468703 + 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase%3B catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2%2C5-hexodiulosonate gene gene457 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02295 UM146_RS02300 UM146_02215 UM146_RS02300 468733 469494 + 2-deoxy-D-gluconate 3-dehydrogenase catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate gene gene458 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02300 UM146_RS02305 UM146_02220 UM146_RS02305 469809 471227 + D-galactose transporter gene gene459 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02305 UM146_RS02310 UM146_02225 UM146_RS02310 471356 472048 + racemase gene gene460 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02310 UM146_RS02315 UM146_02230 UM146_RS02315 472035 472970 - transcriptional regulator activates the transcription of the lysA gene encoding diaminopimelate decarboxylase gene gene461 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02315 UM146_RS02320 UM146_02235 UM146_RS02320 473092 474354 + diaminopimelate decarboxylase catalyzes the decarboxylation of diaminopimelate into lysine%3B pyridoxal phosphate(PLP)-binding gene gene462 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02320 UM146_RS02325 UM146_02240 UM146_RS02325 474361 475392 - transcriptional regulator controls transcription of galETKM gene gene463 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02325 UM146_RS02330 UM146_02245 UM146_RS02330 475978 478137 + bifunctional protein Aas Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 gene gene464 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02330 UM146_RS02335 UM146_02250 UM146_RS02335 478130 479323 + lysophospholipid transporter LplT gene gene465 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02335 UM146_RS02340 UM146_02255 tas tas 479355 480395 - protein tas complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain%3B member of the aldo/keto reductase 2 family%3B crystal structure of purified Escherichia coli protein shows bound NADPH gene gene466 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02340 UM146_RS02345 UM146_02260 UM146_RS02345 480503 480721 - hypothetical protein gene gene467 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02345 UM146_RS02350 UM146_02265 UM146_RS02350 480859 481572 - membrane protein gene gene468 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02350 UM146_RS02355 UM146_02270 UM146_RS02355 481641 482330 - DNA mismatch repair protein MutH MutH%3B Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair gene gene469 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02355 UM146_RS02360 UM146_RS02360 UM146_RS02360 482409 482570 - hypothetical protein gene gene470 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02360 UM146_RS02365 UM146_RS02365 UM146_RS02365 482509 482703 - hypothetical protein gene gene471 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02365 UM146_RS02370 UM146_02275 UM146_RS02370 483015 483545 + RNA pyrophosphohydrolase hydrolyzes diadenosine polyphosphate gene gene472 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02370 UM146_RS02375 UM146_02280 UM146_RS02375 483558 485804 + phosphoenolpyruvate-protein phosphotransferase member of a second PTS chain involved in nitrogen metabolism%3B PtsP phosphorylates NPr gene gene473 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02375 UM146_RS02380 UM146_02285 UM146_RS02380 485955 486830 + prolipoprotein diacylglyceryl transferase gene gene474 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02380 UM146_RS02385 UM146_02290 UM146_RS02385 486837 487631 + thymidylate synthase gene gene475 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02385 UM146_RS02390 UM146_02295 UM146_RS02390 487816 488286 + hypothetical protein gene gene476 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02390 UM146_RS02395 UM146_02300 UM146_RS02395 488277 488840 + hypothetical protein gene gene477 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02395 UM146_RS02400 UM146_02305 UM146_RS02400 488837 489244 + hypothetical protein gene gene478 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02400 UM146_RS02405 UM146_02310 UM146_RS02405 489229 489552 + hypothetical protein gene gene479 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02405 UM146_RS02410 UM146_02315 recC recC 489565 492933 + exonuclease V subunit gamma catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides%3B component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination gene gene480 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02410 UM146_RS02415 UM146_02320 UM146_RS02415 493109 495997 + protease degrades small peptides gene gene481 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02415 UM146_RS02420 UM146_02325 recB recB 495990 499532 + exonuclease V subunit beta helicase/nuclease%3B with RecCD catalyzes the exonucleolytic cleavage of DNA%3B RecD has 5' to 3' helicase activity gene gene482 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02420 UM146_RS02425 UM146_02330 recD recD 499532 501358 + exonuclease V subunit alpha helicase/nuclease%3B with RecBC catalyzes the exonucleolytic cleavage of DNA%3B RecD has 5' to 3' helicase activity gene gene483 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02425 UM146_RS02430 UM146_02335 UM146_RS02430 501420 502751 - amino-acid acetyltransferase catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis gene gene484 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02430 UM146_RS02435 UM146_02340 amiC amiC 502983 504236 + N-acetylmuramoyl-L-alanine amidase hydrolyzes the bond between N-acetylmuramic acid and amino acid residues in peptidoglycan gene gene485 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02435 UM146_RS02440 UM146_RS02440 UM146_RS02440 504494 505305 + antitermination protein gene gene486 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02440 UM146_RS02445 UM146_02355 UM146_RS02445 505337 506917 + PTS glucose transporter subunit IIBC gene gene487 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02445 UM146_RS02450 UM146_RS02450 UM146_RS02450 506917 508091 + beta-cystathionase gene gene488 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02450 UM146_RS02455 UM146_02370 UM146_RS02455 508094 508690 + isomerase gene gene489 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02455 UM146_RS02460 UM146_02375 UM146_RS02460 508762 509709 + phosphoglycerate dehydrogenase gene gene490 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02460 UM146_RS02465 UM146_02380 UM146_RS02465 510011 511387 - hypothetical protein gene gene491 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02465 UM146_RS02470 UM146_02385 UM146_RS02470 511387 511815 - hypothetical protein gene gene492 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02470 UM146_RS02475 UM146_02390 UM146_RS02475 511819 512355 - type VI secretion protein gene gene493 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02475 UM146_RS02480 UM146_02395 UM146_RS02480 512336 513415 - hypothetical protein gene gene494 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02480 UM146_RS02485 UM146_02400 UM146_RS02485 513379 515139 - type VI secretion protein ImpG gene gene495 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02485 UM146_RS02490 UM146_02405 UM146_RS02490 515509 515952 - hypothetical protein gene gene496 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02490 UM146_RS02495 UM146_02415 UM146_RS02495 516209 516763 - hypothetical protein gene gene497 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02495 UM146_RS02500 UM146_02420 UM146_RS02500 516838 518415 - hypothetical protein gene gene498 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02500 UM146_RS02505 UM146_02425 UM146_RS02505 518421 520058 - hypothetical protein gene gene499 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02505 UM146_RS02510 UM146_02430 UM146_RS02510 520024 523377 - type VI secretion protein VasK gene gene500 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02510 UM146_RS02515 UM146_02435 UM146_RS02515 523387 524523 - hypothetical protein gene gene501 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02515 UM146_RS02520 UM146_02440 UM146_RS02520 524525 524785 - hypothetical protein gene gene502 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02520 UM146_RS02525 UM146_RS02525 UM146_RS02525 525249 525542 - hypothetical protein gene gene503 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02525 UM146_RS02530 UM146_RS02530 UM146_RS02530 525511 526344 - hypothetical protein gene gene504 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02530 UM146_RS02535 UM146_02455 UM146_RS02535 526319 528088 - hypothetical protein gene gene505 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02535 UM146_RS02540 UM146_02460 UM146_RS02540 528108 530588 - type IV secretion protein Rhs gene gene506 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02540 UM146_RS02545 UM146_02465 UM146_RS02545 530600 533245 - ATPase gene gene507 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02545 UM146_RS02550 UM146_02470 UM146_RS02550 533437 533928 - Hcp family type VI secretion system effector gene gene508 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02550 UM146_RS02555 UM146_02475 UM146_RS02555 533986 535638 - hypothetical protein gene gene509 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02555 UM146_RS02560 UM146_02480 UM146_RS02560 535651 536316 - type VI secretion protein ImpK gene gene510 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02560 UM146_RS02565 UM146_02485 UM146_RS02565 536313 537650 - hypothetical protein gene gene511 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02565 UM146_RS02570 UM146_02490 UM146_RS02570 537668 539206 - type VI secretion protein gene gene512 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02570 UM146_RS02575 UM146_02495 UM146_RS02575 539265 539765 - hypothetical protein gene gene513 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02575 UM146_RS02580 UM146_t23829 UM146_RS02580 540401 540477 - tRNA-Met tRNA gene514 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02580 UM146_RS02585 UM146_t23831 UM146_RS02585 540512 540588 - tRNA-Met tRNA gene515 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02585 UM146_RS02590 UM146_t23833 UM146_RS02590 540622 540698 - tRNA-Met tRNA gene516 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02590 UM146_RS02595 UM146_02500 mltA mltA 540907 542004 + murein transglycosylase membrane-bound%2C lytic%3B catalyzes the cleavage of the beta-1%2C4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues gene gene517 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02595 UM146_RS02600 UM146_02505 UM146_RS02600 542081 542887 + sulfur acceptor protein CsdL accepts sulfur from CsdA gene gene518 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02600 UM146_RS02605 UM146_02510 UM146_RS02605 542938 543381 - hypothetical protein binds and activates CsdA%3B Fe-S protein gene gene519 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02605 UM146_RS02610 UM146_02515 UM146_RS02610 543381 544586 - cysteine sulfinate desulfinase gene gene520 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02610 UM146_RS02615 UM146_02520 UM146_RS02615 544778 545005 + DUF903 domain-containing protein gene gene521 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02615 UM146_RS02620 UM146_02525 UM146_RS02620 545356 546273 + glycine cleavage system transcriptional activator Glycine cleavage system transcriptional activator%3B activates the gcvTHP operon in the presence of glycine and represses the operon in its absence gene gene522 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02620 UM146_RS02625 UM146_02530 UM146_RS02625 546292 546687 + membrane protein gene gene523 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02625 UM146_RS02630 UM146_02535 UM146_RS02630 546680 547780 + ribosomal RNA large subunit methyltransferase M gene gene524 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02630 UM146_RS02635 UM146_02540 UM146_RS02635 547824 548555 - transcriptional regulator regulates expression of genes involved in L-fucose utilization gene gene525 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02635 UM146_RS02640 UM146_02545 UM146_RS02640 548613 549035 - L-fucose mutarotase gene gene526 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02640 UM146_RS02645 UM146_02550 UM146_RS02645 549037 550455 - L-fuculokinase gene gene527 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02645 UM146_RS02650 UM146_02555 fucI fucI 550564 552339 - L-fucose isomerase catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose gene gene528 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02650 UM146_RS02655 UM146_02560 UM146_RS02655 552372 553688 - L-fucose transporter gene gene529 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02655 UM146_RS02660 UM146_02565 UM146_RS02660 554235 554882 + L-fuculose phosphate aldolase catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate gene gene530 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02660 UM146_RS02665 UM146_02570 UM146_RS02665 554910 556058 + L-1%2C2-propanediol oxidoreductase gene gene531 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02665 UM146_RS02670 UM146_02575 UM146_RS02670 556163 556918 - flap endonuclease Xni similar to flap endonuclease%3B FEN family%3B protein from E. coli does not have exonuclease activity gene gene532 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02670 UM146_RS02675 UM146_02580 UM146_RS02675 557030 558397 - L-serine dehydratase catalyzes the formation of pyruvate from serine gene gene533 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02675 UM146_RS02680 UM146_02585 UM146_RS02680 558455 559744 - serine/threonine transporter gene gene534 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02680 UM146_RS02685 UM146_02590 UM146_RS02685 560301 561665 - LOG family protein YgdH gene gene535 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02685 UM146_RS02690 UM146_02595 queF queF 561777 562625 - NADPH-dependent 7-cyano-7-deazaguanine reductase catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis gene gene536 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02690 UM146_RS02695 UM146_02600 UM146_RS02695 562693 563238 + protein Syd SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function gene gene537 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02695 UM146_RS02700 UM146_02605 UM146_RS02700 563488 563613 + hypothetical protein gene gene538 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02700 UM146_RS02705 UM146_02610 UM146_RS02705 563860 564189 + hypothetical protein gene gene539 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02705 UM146_RS02710 UM146_02615 UM146_RS02710 564189 564971 + tRNA pseudouridine synthase C catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp gene gene540 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02710 UM146_RS02715 UM146_02620 UM146_RS02715 564989 565438 + flavodoxin An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group gene gene541 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02715 UM146_RS02720 UM146_02625 UM146_RS02720 565872 567224 + glucarate transporter gene gene542 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02720 UM146_RS02725 UM146_02630 UM146_RS02725 567226 568566 + glucarate dehydratase gene gene543 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02725 UM146_RS02730 UM146_02635 gudD gudD 568587 569927 + glucarate dehydratase catalyzes the formation of 5-keto-4-deoxy-D-glucarate from glucarate gene gene544 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02730 UM146_RS02735 UM146_02640 UM146_RS02735 570158 572914 - sensor histidine kinase part of the two-component regulatory system with UvrY%3B involved in the regulation of carbon metabolism via the csrA/csrB regulatory system gene gene545 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02735 UM146_RS02740 UM146_02645 rumA rumA 572971 574272 + 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA%3B binds an iron-sulfur cluster [4Fe-4S] gene gene546 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02740 UM146_RS02745 UM146_02650 relA relA 574320 576554 + GTP pyrophosphokinase (p)ppGpp synthetase%3B catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP gene gene547 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02745 UM146_RS02750 UM146_02655 UM146_RS02750 576632 576880 + antitoxin MazE part of the MazF-MazE toxin-antitoxin system%3B conteracts MazF gene gene548 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02750 UM146_RS02755 UM146_02660 UM146_RS02755 576880 577215 + toxin ChpA%3B endoribonuclease%3B toxin of the MazF-MazE (ChpA-ChpR) toxin-antitoxin system gene gene549 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02755 UM146_RS02760 UM146_02665 mazG mazG 577287 578078 + nucleoside triphosphate pyrophosphohydrolase functions in degradation of stringent response intracellular messenger ppGpp%3B in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF%3B activity of MazG is inhibited by MazEF in vitro%3B ppGpp inhibits mazEF expression%3B MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation%3B MazG also interacts with the GTPase protein Era gene gene550 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02760 UM146_RS02765 UM146_02670 pyrG pyrG 578306 579943 + CTP synthase CTP synthase%3B cytidine triphosphate synthetase%3B catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen%3B in Escherichia coli this enzyme forms a homotetramer gene gene551 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02765 UM146_RS02770 UM146_02675 eno eno 580031 581329 + enolase catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis gene gene552 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02770 UM146_RS02775 UM146_02680 UM146_RS02775 581389 582282 - hypothetical protein gene gene553 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02775 UM146_RS02780 UM146_02685 UM146_RS02780 582288 583436 - membrane protein gene gene554 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02780 UM146_RS02785 UM146_02690 UM146_RS02785 583451 584344 - membrane protein gene gene555 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02785 UM146_RS02790 UM146_02695 UM146_RS02790 584358 584972 - hypothetical protein gene gene556 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02790 UM146_RS02795 UM146_02700 UM146_RS02795 585145 585816 + 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE gene gene557 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02795 UM146_RS02805 UM146_02705 UM146_RS02805 586290 587768 - sugar kinase gene gene558 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02805 UM146_RS02810 UM146_RS02810 UM146_RS02810 587795 589071 - hypothetical protein gene gene559 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02810 UM146_RS02815 UM146_02720 UM146_RS02815 589390 590175 + oxidoreductase gene gene560 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02815 UM146_RS02820 UM146_02725 UM146_RS02820 590245 591699 + FAD-linked oxidoreductase gene gene561 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02820 UM146_RS02825 UM146_02730 UM146_RS02825 591793 593130 + MFS transporter gene gene562 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02825 UM146_RS02830 UM146_RS02830 UM146_RS02830 593108 593886 + electron transfer flavoprotein gene gene563 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02830 UM146_RS02835 UM146_02745 UM146_RS02835 593883 594743 + electron transfer flavoprotein gene gene564 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02835 UM146_RS02840 UM146_02750 UM146_RS02840 594891 595466 - hypothetical protein gene gene565 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02840 UM146_RS02845 UM146_02755 UM146_RS02845 595483 595743 - ferredoxin gene gene566 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02845 UM146_RS02850 UM146_02760 UM146_RS02850 595734 597005 - FAD-dependent oxidoreductase gene gene567 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02850 UM146_RS02855 UM146_02765 UM146_RS02855 597083 597445 - 6-carboxy-5%2C6%2C7%2C8-tetrahydropterin synthase gene gene568 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02855 UM146_RS02860 UM146_02770 cysJ cysJ 597764 599563 + sulfite reductase subunit alpha catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate%3B a flavoprotein with flavin reductase activity gene gene569 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02860 UM146_RS02865 UM146_02775 UM146_RS02865 599563 601275 + sulfite reductase subunit beta hemoprotein%3B NADPH dependent%3B with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide gene gene570 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02865 UM146_RS02870 UM146_02780 UM146_RS02870 601349 602083 + phosphoadenosine phosphosulfate reductase catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite gene gene571 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02870 UM146_RS02875 UM146_02785 UM146_RS02875 602348 602500 + protein hokG gene gene572 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02875 UM146_RS02880 UM146_02790 UM146_RS02880 602625 603662 - alkaline phosphatase isozyme conversion aminopeptidase catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3 gene gene573 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02880 UM146_RS02885 UM146_02795 UM146_RS02885 603914 604822 + sulfate adenylyltransferase subunit 2 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP gene gene574 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02885 UM146_RS02890 UM146_02800 cysN cysN 604824 606251 + sulfate adenylyltransferase subunit 1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate%3B in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step%3B forms a heterodimer with CysD%3B part of the GTP-binding elongation factor family CysN/NodQ gene gene575 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02890 UM146_RS02895 UM146_02805 UM146_RS02895 606251 606856 + adenylyl-sulfate kinase converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate%3B in Escherichia coli this enzyme functions in cysteine biosynthesis gene gene576 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02895 UM146_RS02900 UM146_02810 UM146_RS02900 606906 607229 + membrane protein gene gene577 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02900 UM146_RS02905 UM146_02815 ftsB ftsB 607422 607733 + cell division protein FtsB forms a complex with FtsL and FtsQ%3B colocalizes to the septal region of the dividing cell%3B membrane protein gene gene578 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02905 UM146_RS02910 UM146_02820 UM146_RS02910 607752 608462 + 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase gene gene579 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02910 UM146_RS02915 UM146_02825 ispF ispF 608462 608941 + 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate gene gene580 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02915 UM146_RS02920 UM146_02830 truD truD 608938 609987 + tRNA pseudouridine synthase D catalyzes the modification of U13 in tRNA(Glu) gene gene581 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02920 UM146_RS02925 UM146_02835 surE surE 609968 610729 + 5'/3'-nucleotidase SurE broad specificity 5'(3')-nucleotidase and polyphosphatase gene gene582 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02925 UM146_RS02930 UM146_02840 pcm pcm 610723 611349 + protein-L-isoaspartate O-methyltransferase catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins gene gene583 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02930 UM146_RS02935 UM146_02845 nlpD nlpD 611489 612628 + lipoprotein NlpD outer membrane lipoprotein involved in stationary-phase cell survival%3B similar to LppB virulence determinant from Haemophilus somnus gene gene584 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02935 UM146_RS02940 UM146_02850 UM146_RS02940 612691 613683 + RNA polymerase sigma factor RpoS sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B this sigma factor controls a regulon of genes required for protection against external stresses gene gene585 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02940 UM146_RS02945 UM146_02855 UM146_RS02945 613861 614412 - FMN reductase gene gene586 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02945 UM146_RS02950 UM146_02860 UM146_RS02950 614637 615680 + lactamase gene gene587 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02950 UM146_RS02955 UM146_02865 UM146_RS02955 615823 617187 - transporter member of the Gnt family of gluconate transporters%3B not involved in gluconate transport%3B unknown function gene gene588 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02955 UM146_RS02960 UM146_02870 UM146_RS02960 617276 618052 - hypothetical protein gene gene589 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02960 UM146_RS02965 UM146_02875 UM146_RS02965 618057 618695 - aldolase gene gene590 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02965 UM146_RS02970 UM146_02880 UM146_RS02970 618692 619954 - membrane protein gene gene591 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02970 UM146_RS02975 UM146_02885 UM146_RS02975 619951 620859 - oxidoreductase gene gene592 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02975 UM146_RS02980 UM146_02890 UM146_RS02980 621055 621822 + DeoR family transcriptional regulator gene gene593 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02980 UM146_RS02985 UM146_02895 UM146_RS02985 621873 622190 - serine/threonine protein phosphatase gene gene594 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02985 UM146_RS02990 UM146_02900 UM146_RS02990 622252 622527 + transposase gene gene595 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02990 UM146_RS02995 UM146_02905 UM146_RS02995 622446 622949 + transposase gene gene596 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS02995 UM146_RS03000 UM146_02910 UM146_RS03000 623214 625775 - DNA mismatch repair protein MutS This protein performs the mismatch recognition step during the DNA repair process gene gene597 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03000 UM146_RS03005 UM146_02915 UM146_RS03005 626061 626405 + hypothetical protein gene gene598 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03005 UM146_RS03010 UM146_02920 UM146_RS03010 626444 626872 - transporter gene gene599 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03010 UM146_RS03015 UM146_02925 UM146_RS03015 626917 628995 - transcriptional regulator regulates the expression of formate dehydrogenase H and hydrogenase-3 structural genes gene gene600 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03015 UM146_RS03020 UM146_02930 UM146_RS03020 629069 630079 - carbamoyl dehydratase hydrogenase isoenzymes formation protein%3B involved in the formation of the cyanate group of the large subunit of the hydrogenase%3B catalyzes the formation of thiocyanate from thiocarbamate gene gene601 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03020 UM146_RS03025 UM146_02935 UM146_RS03025 630076 631197 - hydrogenase formation protein HypD necessary for the synthesis of all three hydrogenase isoenzymes gene gene602 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03025 UM146_RS03030 UM146_02940 UM146_RS03030 631197 631469 - hydrogenase assembly protein HypC HypC%3B accessory protein necessary for maturation of the hydrogenase isoforms 1%2C 2 and 3%3B forms a complex with HypD%2C HypE%2C and HypF proteins%2C which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase gene gene603 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03030 UM146_RS03035 UM146_02945 UM146_RS03035 631460 632332 - hydrogenase nickel incorporation protein HypB GTP hydrolase involved in nickel liganding into hydrogenases gene gene604 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03035 UM146_RS03040 UM146_02950 hypA hypA 632336 632686 - protein HypA plays a role in hydrogenase nickel cofactor insertion gene gene605 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03040 UM146_RS03045 UM146_02955 UM146_RS03045 632898 633359 + formate hydrogenlyase regulatory protein HycA regulates several genes involved in the formate hydrogenlyase system%3B seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon gene gene606 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03045 UM146_RS03050 UM146_02960 UM146_RS03050 633484 634095 + formate hydrogenlyase subunit 2 gene gene607 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03050 UM146_RS03055 UM146_02965 UM146_RS03055 634092 635918 + formate hydrogenlyase subunit 3 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen%3B formate hydrogenlyase comprises of a formate dehydrogenase%2C unidentified electron carriers and a hydrogenase (subunit 3) gene gene608 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03055 UM146_RS03060 UM146_02970 hycD hycD 635921 636844 + hydrogenase 3 membrane subunit formate hydrogenlyase subunit 4%3B HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide gene gene609 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03060 UM146_RS03065 UM146_02975 hycE hycE 636862 638571 + formate hydrogenlyase subunit 5 formate hydrogenlyase subunit 5%3B HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide gene gene610 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03065 UM146_RS03070 UM146_02980 UM146_RS03070 638581 639123 + formate hydrogenlyase complex iron-sulfur subunit electron transfer protein for hydrogenase-3%3B the formate hydrogenlyase complex comprises of a formate dehydrogenase%2C unidentified electron carriers and hydrogenase-3%3B in this non-energy conserving pathway%2C molecular hydrogen and carbodioxide are released from formate gene gene611 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03070 UM146_RS03075 UM146_02985 UM146_RS03075 639123 639890 + formate hydrogenlyase subunit 7 gene gene612 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03075 UM146_RS03080 UM146_02990 UM146_RS03080 639887 640297 + formate hydrogenlyase maturation protein HycH required for the maturation of the formate hydrogenlyase complex gene gene613 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03080 UM146_RS03085 UM146_02995 hycI hycI 640290 640760 + hydrogenase 3 maturation protease involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE gene gene614 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03085 UM146_RS03090 UM146_03005 UM146_RS03090 641005 641424 + XRE family transcriptional regulator gene gene615 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03090 UM146_RS03095 UM146_03010 UM146_RS03095 641522 642946 - 6-phospho-beta-glucosidase gene gene616 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03095 UM146_RS03100 UM146_03015 UM146_RS03100 642955 644412 - PTS cellobiose transporter subunit IIBC phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene617 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03100 UM146_RS03105 UM146_03020 UM146_RS03105 644672 645682 + transcriptional regulator gene gene618 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03105 UM146_RS03110 UM146_03025 UM146_RS03110 645831 646358 + electron transporter HydN involved in electron transport from formate to hydrogen gene gene619 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03110 UM146_RS03115 UM146_03030 UM146_RS03115 646511 648763 + carbamoyl phosphate phosphatase carbamoyltransferase%3B involved in the formation of the cyanate group of hydrogenase%3B catalyzes the formation of carbamoyladenylate from carbamoylphosphate and then transfers the carbamoyl group to HypE gene gene620 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03115 UM146_RS03120 UM146_03035 UM146_RS03120 648987 650120 - nitric oxide reductase FlRd-NAD+ reductase gene gene621 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03120 UM146_RS03125 UM146_03040 UM146_RS03125 650117 651556 - anaerobic nitric oxide reductase flavorubredoxin detoxifies nitric oxide using NADH gene gene622 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03125 UM146_RS03130 UM146_03045 UM146_RS03130 651743 653257 + NorR family transcriptional regulator Required for the expression of anaerobic nitric oxide (NO) reductase%3B acts as a transcriptional activator for the norVW operon gene gene623 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03130 UM146_RS03135 UM146_03050 UM146_RS03135 653254 654219 - arabinose 5-phosphate isomerase gene gene624 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03135 UM146_RS03140 UM146_03055 srlR srlR 654212 654985 - transcriptional regulator regulates genes involved in glucitol utilization gene gene625 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03140 UM146_RS03145 UM146_03060 UM146_RS03145 655052 655411 - transcriptional regulator regulator for glucitol utilization gene gene626 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03145 UM146_RS03150 UM146_03065 UM146_RS03150 655517 656296 - sorbitol-6-phosphate dehydrogenase catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate gene gene627 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03150 UM146_RS03155 UM146_03070 UM146_RS03155 656300 656671 - PTS sorbitol transporter subunit IIA phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene628 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03155 UM146_RS03160 UM146_03075 srlE srlE 656682 657641 - PTS sorbitol transporter subunit IIB catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B subunit IIB transfers the phosphoryl group to the substrate gene gene629 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03160 UM146_RS03165 UM146_03080 srlA srlA 657638 658201 - PTS sorbitol transporter subunit IIC catalyzes the phosphorylation of incoming sugar substrates along with their translocation across the cell membrane%3B the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site gene gene630 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03165 UM146_RS03170 UM146_03085 UM146_RS03170 658458 659543 + murein hydrolase B membrane-bound lytic murein transglycosylase B%3B catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan gene gene631 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03170 UM146_RS03175 UM146_03090 UM146_RS03175 659688 660185 + nicotinamide-nucleotide amidohydrolase PncC gene gene632 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03175 UM146_RS03180 UM146_03095 recA recA 660265 661326 + protein RecA catalyzes the hydrolysis of ATP in the presence of single-stranded DNA%2C the ATP-dependent uptake of single-stranded DNA by duplex DNA%2C and the ATP-dependent hybridization of homologous single-stranded DNAs gene gene633 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03180 UM146_RS03185 UM146_03100 recX recX 661395 661895 + regulatory protein RecX binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities gene gene634 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03185 UM146_RS03190 UM146_03105 UM146_RS03190 661936 662085 - hypothetical protein gene gene635 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03190 UM146_RS03195 UM146_03110 UM146_RS03195 662023 664653 + alanine--tRNA ligase gene gene636 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03195 UM146_RS03200 UM146_03115 UM146_RS03200 664888 665073 + pleiotropic regulatory protein for carbon source metabolism affects carbohydrate metabolism%3B has regulatory role in many processes gene gene637 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03200 UM146_RS03205 UM146_t23835 UM146_RS03205 665389 665481 + tRNA-Ser tRNA gene638 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03205 UM146_RS03210 UM146_t23837 UM146_RS03210 665485 665561 + tRNA-Arg tRNA gene639 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03210 UM146_RS03215 UM146_t23839 UM146_RS03215 665626 665702 + tRNA-Arg tRNA gene640 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03215 UM146_RS03220 UM146_t23841 UM146_RS03220 665766 665842 + tRNA-Arg tRNA gene641 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03220 UM146_RS03225 UM146_03125 UM146_RS03225 666123 666689 + fructose-1-P/6-phosphogluconate phosphatase YqaB%3B catalyzes the dephosphorylation of fructose 1-phosphate%2C 6-phosphogluconate and p-nitrophenyl phosphate (pNPP)%3B presents beta-phosphoglucomutase activity at a lower extent gene gene642 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03225 UM146_RS03230 UM146_RS03230 UM146_RS03230 666686 667099 + membrane protein gene gene643 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03230 UM146_RS03235 UM146_03135 UM146_RS03235 667186 668742 + glutamate--cysteine ligase involved in the first step of glutathione biosynthesis gene gene644 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03235 UM146_RS03240 UM146_03140 UM146_RS03240 668893 669408 + S-ribosylhomocysteine lyase catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 gene gene645 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03240 UM146_RS03245 UM146_03145 UM146_RS03245 669459 670571 - hypothetical protein gene gene646 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03245 UM146_RS03250 UM146_03150 UM146_RS03250 670568 671275 - 2'-5' RNA ligase gene gene647 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03250 UM146_RS03255 UM146_03155 emrB emrB 671533 673071 - multidrug effux MFS transporter subunit EmrB multidrug MFS transporte%3B with EmrA is involved in resistance to hydrophobic antibiotics such as nalidixic acid gene gene648 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03255 UM146_RS03260 UM146_03160 UM146_RS03260 673088 674260 - multidrug export protein EmrA with ErmA and TolC forms a multidrug efflux system gene gene649 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03260 UM146_RS03265 UM146_03165 UM146_RS03265 674387 674917 - transcriptional regulator DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux%3B negative regulator of the multidrug operon emrAB gene gene650 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03265 UM146_RS03270 UM146_03170 UM146_RS03270 675008 675343 - branched-chain amino acid ABC transporter permease gene gene651 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03270 UM146_RS03275 UM146_03175 UM146_RS03275 675333 676070 - hypothetical protein gene gene652 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03275 UM146_RS03280 UM146_03180 UM146_RS03280 676194 677378 - transporter gene gene653 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03280 UM146_RS03285 UM146_03185 proX proX 677570 678562 - glycine/betaine ABC transporter substrate-binding protein with ProVW%2C part of the high-affinity transport system for the osmoprotectant glycine betaine gene gene654 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03285 UM146_RS03290 UM146_03190 UM146_RS03290 678620 679684 - glycine/betaine ABC transporter permease with ProVX is involved in the high-affinity uptake of glycine betaine gene gene655 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03290 UM146_RS03295 UM146_03195 UM146_RS03295 679677 680879 - glycine/betaine ABC transporter ATP-binding protein with ProWX is involved in the high-affinity uptake of glycine betaine gene gene656 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03295 UM146_RS03300 UM146_03200 UM146_RS03300 681235 682194 - ribonucleotide-diphosphate reductase subunit beta B2 or R2 protein%3B type 1b enzyme%3B catalyzes the rate-limiting step in dNTP synthesis%3B converts nucleotides to deoxynucleotides%3B forms a homodimer and then a multimeric complex with NrdE gene gene657 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03300 UM146_RS03305 UM146_03205 UM146_RS03305 682204 684348 - ribonucleotide-diphosphate reductase subunit alpha gene gene658 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03305 UM146_RS03310 UM146_03210 nrdI nrdI 684321 684731 - protein NrdI in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF gene gene659 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03310 UM146_RS03315 UM146_03215 UM146_RS03315 684728 684973 - glutaredoxin gene gene660 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03315 UM146_RS03320 UM146_03220 UM146_RS03320 685182 685613 - alkylhydroperoxidase gene gene661 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03320 UM146_RS03325 UM146_03225 UM146_RS03325 685701 687035 + DNA-binding transcriptional regulator gene gene662 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03325 UM146_RS03330 UM146_03230 UM146_RS03330 687092 687421 - DUF883 domain-containing protein gene gene663 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03330 UM146_RS03335 UM146_03235 UM146_RS03335 687573 687917 + hypothetical protein gene gene664 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03335 UM146_RS03340 UM146_03240 UM146_RS03340 687954 688403 - membrane protein gene gene665 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03340 UM146_RS03345 UM146_03245 UM146_RS03345 689071 689475 + DNA-binding protein gene gene666 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03345 UM146_RS03350 UM146_RS03350 UM146_RS03350 689522 690046 - hypothetical protein gene gene667 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03350 UM146_RS03355 UM146_03255 UM146_RS03355 690056 690355 - transcriptional regulator gene gene668 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03355 UM146_RS03360 UM146_03260 UM146_RS03360 690538 690696 + hypothetical protein gene gene669 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03360 UM146_RS03365 UM146_03265 UM146_RS03365 690780 691229 + peptidoglycan-binding protein LysM gene gene670 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03365 UM146_RS03370 UM146_03270 UM146_RS03370 691230 691892 - transcriptional regulator regulator of gab gene expression gene gene671 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03370 UM146_RS03375 UM146_03275 UM146_RS03375 691913 693313 - GABA permease gene gene672 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03375 UM146_RS03380 UM146_03280 UM146_RS03380 693551 694831 - 4-aminobutyrate aminotransferase gene gene673 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03380 UM146_RS03385 UM146_03285 gabD gabD 694845 696293 - succinate-semialdehyde dehydrogenase catalyzes the formation of succinate from succinate semialdehyde%3B NADP dependent gene gene674 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03385 UM146_RS03390 UM146_03290 UM146_RS03390 696316 697584 - hydroxyglutarate oxidase catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate gene gene675 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03390 UM146_RS03395 UM146_03295 UM146_RS03395 697604 698581 - protein CsiD in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP%3B the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases%3B forms homotetramers in solution gene gene676 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03395 UM146_RS03400 UM146_03300 UM146_RS03400 699213 699476 - hypothetical protein gene gene677 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03400 UM146_RS03405 UM146_03305 UM146_RS03405 699442 700353 + hypothetical protein gene gene678 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03405 UM146_RS03410 UM146_03310 UM146_RS03410 700358 700684 + hypothetical protein gene gene679 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03410 UM146_RS03415 UM146_03315 UM146_RS03415 700713 701312 + hypothetical protein gene gene680 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03415 UM146_RS03420 UM146_03320 UM146_RS03420 701304 702476 - integrase gene gene681 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03420 UM146_RS03425 UM146_03330 UM146_RS03425 703659 704183 - hypothetical protein gene gene682 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03425 UM146_RS03430 UM146_03335 UM146_RS03430 704311 705135 - hypothetical protein gene gene683 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03430 UM146_RS03435 UM146_RS03435 UM146_RS03435 705201 705563 - hypothetical protein gene gene684 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03435 UM146_RS03440 UM146_RS03440 UM146_RS03440 705663 705860 + hypothetical protein gene gene685 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03440 UM146_RS03445 UM146_03340 UM146_RS03445 706032 706544 + hypothetical protein gene gene686 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03445 UM146_RS03450 UM146_03345 UM146_RS03450 706747 707421 - e14 prophage%3B repressor protein phage e14 gene gene687 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03450 UM146_RS03455 UM146_03350 UM146_RS03455 707512 707712 + transcriptional regulator gene gene688 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03455 UM146_RS03460 UM146_03355 UM146_RS03460 707756 708307 + hypothetical protein gene gene689 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03460 UM146_RS03465 UM146_03360 UM146_RS03465 708304 708642 + hypothetical protein gene gene690 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03465 UM146_RS03470 UM146_RS03470 UM146_RS03470 708652 709592 + replication protein gene gene691 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03470 UM146_RS03475 UM146_03375 UM146_RS03475 709595 710083 + hypothetical protein gene gene692 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03475 UM146_RS03480 UM146_03380 UM146_RS03480 710083 710736 + methyltransferase gene gene693 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03480 UM146_RS03485 UM146_03385 UM146_RS03485 710733 711059 + LexA family transcriptional regulator gene gene694 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03485 UM146_RS03490 UM146_03390 UM146_RS03490 711056 711445 + crossover junction endodeoxyribonuclease gene gene695 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03490 UM146_RS03495 UM146_03395 UM146_RS03495 711465 712262 + hypothetical protein gene gene696 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03495 UM146_RS03500 UM146_03400 UM146_RS03500 712270 713259 + hypothetical protein gene gene697 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03500 UM146_RS03505 UM146_03405 UM146_RS03505 713273 714025 + antitermination protein gene gene698 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03505 UM146_RS03510 UM146_03410 UM146_RS03510 714211 714546 + hypothetical protein gene gene699 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03510 UM146_RS03515 UM146_RS03515 UM146_RS03515 714698 715004 + holin gene gene700 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03515 UM146_RS03520 UM146_03420 UM146_RS03520 714991 715467 + lysozyme gene gene701 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03520 UM146_RS03525 UM146_03425 UM146_RS03525 715464 715901 + endopeptidase gene gene702 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03525 UM146_RS03530 UM146_03430 UM146_RS03530 715972 716223 + hypothetical protein gene gene703 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03530 UM146_RS03535 UM146_RS03535 UM146_RS03535 716330 716769 - hypothetical protein gene gene704 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03535 UM146_RS03540 UM146_03440 UM146_RS03540 716872 717222 + endonuclease gene gene705 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03540 UM146_RS03545 UM146_RS03545 UM146_RS03545 717347 717840 + terminase gene gene706 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03545 UM146_RS03550 UM146_03455 UM146_RS03550 717837 719570 + terminase gene gene707 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03550 UM146_RS03555 UM146_03460 UM146_RS03555 719582 719764 + hypothetical protein gene gene708 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03555 UM146_RS03560 UM146_03465 UM146_RS03560 719764 721005 + portal protein gene gene709 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03560 UM146_RS03565 UM146_03470 UM146_RS03565 720983 721633 + primosome assembly protein PriA gene gene710 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03565 UM146_RS03570 UM146_03475 UM146_RS03570 721648 722853 + phage capsid protein gene gene711 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03570 UM146_RS03575 UM146_03480 UM146_RS03575 722903 723103 + hypothetical protein gene gene712 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03575 UM146_RS03580 UM146_03485 UM146_RS03580 723106 723429 + hypothetical protein gene gene713 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03580 UM146_RS03585 UM146_03490 UM146_RS03585 723426 723836 + phage head-tail adapter protein gene gene714 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03585 UM146_RS03590 UM146_03495 UM146_RS03590 723811 724317 + hypothetical protein gene gene715 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03590 UM146_RS03595 UM146_03500 UM146_RS03595 724314 724874 + hypothetical protein gene gene716 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03595 UM146_RS03600 UM146_03505 UM146_RS03600 724883 725053 + hypothetical protein gene gene717 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03600 UM146_RS03605 UM146_03510 UM146_RS03605 725037 726533 + tail sheath protein gene gene718 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03605 UM146_RS03610 UM146_03515 UM146_RS03610 726533 726889 + hypothetical protein gene gene719 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03610 UM146_RS03615 UM146_RS03615 UM146_RS03615 726889 727158 + hypothetical protein gene gene720 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03615 UM146_RS03620 UM146_03520 UM146_RS03620 727300 729135 + phage tail tape measure protein gene gene721 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03620 UM146_RS03625 UM146_03525 UM146_RS03625 729196 730524 + DNA circularization protein gene gene722 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03625 UM146_RS03630 UM146_03530 UM146_RS03630 730521 731600 + baseplate protein gene gene723 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03630 UM146_RS03635 UM146_03535 UM146_RS03635 731600 732148 + baseplate assembly protein gene gene724 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03635 UM146_RS03640 UM146_03540 UM146_RS03640 732148 732573 + hypothetical protein gene gene725 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03640 UM146_RS03645 UM146_03545 UM146_RS03645 732560 733618 + phage baseplate protein gene gene726 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03645 UM146_RS03650 UM146_03550 UM146_RS03650 733609 734193 + hypothetical protein gene gene727 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03650 UM146_RS03655 UM146_RS03655 UM146_RS03655 734197 734478 + hypothetical protein gene gene728 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03655 UM146_RS03665 UM146_03565 UM146_RS03665 734941 735543 + tail assembly protein gene gene729 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03665 UM146_RS03670 UM146_03570 UM146_RS03670 735515 735958 - hypothetical protein gene gene730 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03670 UM146_RS03675 UM146_03575 UM146_RS03675 735961 736356 - hypothetical protein gene gene731 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03675 UM146_RS03680 UM146_03580 UM146_RS03680 736484 736612 + hypothetical protein gene gene732 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03680 UM146_RS03685 UM146_03585 UM146_RS03685 736691 738598 - hypothetical protein gene gene733 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03685 UM146_RS03695 UM146_03595 UM146_RS03695 739650 740423 + hypothetical protein gene gene735 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03695 UM146_RS03700 UM146_03600 UM146_RS03700 740634 740927 + hypothetical protein gene gene736 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03700 UM146_RS03705 UM146_03605 UM146_RS03705 741015 741803 - hypothetical protein gene gene737 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03705 UM146_RS03710 UM146_03610 UM146_RS03710 741800 741997 - hypothetical protein gene gene738 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03710 UM146_RS03715 UM146_03615 smpB smpB 742960 743442 - SsrA-binding protein binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes%3B also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site%3B SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus%3B both the tmRNA and SmpB are regulated in cell cycle-dependent manner%3B functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation gene gene739 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03715 UM146_RS03720 UM146_03620 UM146_RS03720 743574 744050 + persistence and stress-resistance toxin PasT gene gene740 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03720 UM146_RS03725 UM146_03625 UM146_RS03725 744040 744330 + hypothetical protein gene gene741 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03725 UM146_RS03730 UM146_03630 UM146_RS03730 744392 744733 - outer membrane protein assembly factor BamE gene gene742 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03730 UM146_RS03735 UM146_03635 UM146_RS03735 744882 746543 - DNA repair protein RecN gene gene743 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03735 UM146_RS03740 UM146_03640 ppnK ppnK 746629 747507 - NAD kinase catalyzes the phosphorylation of NAD to NADP gene gene744 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03740 UM146_RS03745 UM146_03645 UM146_RS03745 747630 748223 + protein GrpE with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins%3B may act as a thermosensor gene gene745 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03745 UM146_RS03750 UM146_03650 UM146_RS03750 748278 749519 - hypothetical protein gene gene746 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03750 UM146_RS03755 UM146_03655 UM146_RS03755 749585 750376 - hypothetical protein gene gene747 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03755 UM146_RS03760 UM146_03660 UM146_RS03760 750543 751904 + signal recognition particle protein gene gene748 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03760 UM146_RS03765 UM146_03665 UM146_RS03765 752041 752289 + 30S ribosomal protein S16 gene gene749 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03765 UM146_RS03770 UM146_03670 rimM rimM 752308 752856 + ribosome maturation factor RimM Essential for efficient processing of 16S rRNA gene gene750 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03770 UM146_RS03775 UM146_03675 trmD trmD 752887 753654 + tRNA (guanine-N(1)-)-methyltransferase methylates guanosine-37 in various tRNAs%3B uses S-adenosyl-L-methionine to transfer methyl group to tRNA gene gene751 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03775 UM146_RS03780 UM146_03680 UM146_RS03780 753696 754043 + 50S ribosomal protein L19 gene gene752 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03780 UM146_RS03785 UM146_03685 UM146_RS03785 754120 754602 - membrane protein gene gene753 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03785 UM146_RS03790 UM146_03690 UM146_RS03790 754618 755841 - diguanylate cyclase gene gene754 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03790 UM146_RS03795 UM146_03695 UM146_RS03795 755834 756352 - hypothetical protein gene gene755 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03795 UM146_RS03800 UM146_03700 UM146_RS03800 756499 756864 - lipoprotein gene gene756 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03800 UM146_RS03805 UM146_03705 UM146_RS03805 757074 758144 + phospho-2-dehydro-3-deoxyheptonate aldolase catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate%2C tyrosine sensitive gene gene757 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03805 UM146_RS03810 UM146_03710 tyrA tyrA 758155 759276 + chorismate mutase catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis gene gene758 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03810 UM146_RS03815 UM146_03715 pheA pheA 759319 760479 - bifunctional chorismate mutase/prephenate dehydratase catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis gene gene759 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03815 UM146_RS03820 UM146_03720 UM146_RS03820 760729 761070 - ribosome-associated inhibitor A associated with 30S ribosomal subunit%3B interferes with translation elongation gene gene760 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03820 UM146_RS03825 UM146_RS03825 UM146_RS03825 761105 761311 - hypothetical protein gene gene761 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03825 UM146_RS03830 UM146_03725 UM146_RS03830 761340 762077 - outer membrane protein assembly factor BamD gene gene762 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03830 UM146_RS03835 UM146_03730 rluD rluD 762212 763192 + ribosomal large subunit pseudouridine synthase D responsible for synthesis of pseudouridine from uracil at positions 1911%2C 1915 and 1917 in 23S ribosomal RNA gene gene763 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03835 UM146_RS03840 UM146_03735 UM146_RS03840 763189 763920 + hypothetical protein gene gene764 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03840 UM146_RS03845 UM146_03740 UM146_RS03845 764050 766623 + chaperone protein ClpB gene gene765 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03845 UM146_RS03850 UM146_r24005 UM146_RS03850 767064 768619 + 16S ribosomal RNA rRNA gene767 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03850 UM146_RS03855 UM146_t23843 UM146_RS03855 768693 768768 + tRNA-Glu tRNA gene768 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03855 UM146_RS03860 UM146_r24019 UM146_RS03860 768953 771877 + 23S ribosomal RNA rRNA gene769 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03860 UM146_RS03865 UM146_r23993 UM146_RS03865 771966 772081 + 5S ribosomal RNA rRNA gene770 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03865 UM146_RS03870 UM146_03750 UM146_RS03870 772212 772454 + transposase gene gene771 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03870 UM146_RS03875 UM146_03755 UM146_RS03875 772559 772732 + transposase gene gene772 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03875 UM146_RS03880 UM146_03760 UM146_RS03880 772957 773559 + transposase gene gene773 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03880 UM146_RS03885 UM146_03765 UM146_RS03885 773803 774207 + transposase gene gene774 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03885 UM146_RS03890 UM146_03770 UM146_RS03890 774231 774455 + transposase gene gene775 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03890 UM146_RS03895 UM146_03775 UM146_RS03895 774593 774769 + transposase gene gene776 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03895 UM146_RS03900 UM146_03780 UM146_RS03900 775112 776410 + alpha-ketoglutarate transporter gene gene777 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03900 UM146_RS03905 UM146_03785 UM146_RS03905 776407 776679 - lipoprotein gene gene778 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03905 UM146_RS03910 UM146_03790 pssA pssA 776776 778131 - CDP-diacylglycerol--serine O-phosphatidyltransferase catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine%3B bounds to the ribosome gene gene779 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03910 UM146_RS03915 UM146_03795 UM146_RS03915 778245 780905 - protein lysine acetyltransferase catalyzes the acetylation of lysine gene gene780 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03915 UM146_RS03920 UM146_03800 UM146_RS03920 780937 781635 - hypothetical protein gene gene781 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03920 UM146_RS03925 UM146_03805 UM146_RS03925 781704 782123 - thioredoxin gene gene782 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03925 UM146_RS03930 UM146_RS03930 UM146_RS03930 782182 782340 + hypothetical protein gene gene783 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03930 UM146_RS03935 UM146_03810 UM146_RS03935 782330 783367 + methyltransferase gene gene784 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03935 UM146_RS03940 UM146_03815 UM146_RS03940 783415 784104 - uracil-DNA glycosylase Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine gene gene785 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03940 UM146_RS03945 UM146_03820 UM146_RS03945 784408 784791 + autonomous glycyl radical cofactor GrcA stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit gene gene786 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03945 UM146_RS03950 UM146_03825 UM146_RS03950 784847 785434 - cysteine/O-acetylserine efflux protein gene gene787 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03950 UM146_RS03955 UM146_03830 UM146_RS03955 785537 786418 + LysR family transcriptional regulator gene gene788 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03955 UM146_RS03960 UM146_03835 UM146_RS03960 786451 787785 - ATP-dependent RNA helicase SrmB facilitates an early step in the assembly of the 50S subunit of the ribosome gene gene789 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03960 UM146_RS03965 UM146_03840 UM146_RS03965 787917 788654 + tRNA1(Val) (adenine(37)-N6)-methyltransferase gene gene790 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03965 UM146_RS03970 UM146_03845 UM146_RS03970 788639 790261 - L-aspartate oxidase catalyzes the formation of oxaloacetate from L-aspartate gene gene791 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03970 UM146_RS03975 UM146_03850 UM146_RS03975 790517 790672 + hypothetical protein gene gene792 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03975 UM146_RS03980 UM146_03855 UM146_RS03980 790669 791244 + ECF RNA polymerase sigma-E factor Member of the extracytoplasmic function sigma factors which are active under specific conditions%3B binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription%3B this sigma factor is involved in heat shock and oxidative stress response gene gene793 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03980 UM146_RS03985 UM146_03860 UM146_RS03985 791277 791927 + anti-sigma-E factor RseA gene gene794 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03985 UM146_RS03990 UM146_03865 rseB rseB 791927 792883 + sigma-E factor regulatory protein RseB periplasmic protein%3B interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP gene gene795 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03990 UM146_RS03995 UM146_03870 UM146_RS03995 792880 793359 + SoxR reducing system protein RseC involved in the reduction of the SoxR iron-sulfur cluster gene gene796 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS03995 UM146_RS04000 UM146_03875 UM146_RS04000 793557 795356 + elongation factor 4 gene gene797 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04000 UM146_RS04005 UM146_03880 UM146_RS04005 795372 796346 + signal peptidase I catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins gene gene798 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04005 UM146_RS04010 UM146_03885 rnc rnc 796613 797293 + ribonuclease 3 cytoplasmic enzyme involved in processing rRNA and some mRNAs%3B substrates typically have dsRNA regions%3B forms a homodimer%3B have N-terminal nuclease and C-terminal RNA-binding domains%3B requires magnesium as preferred ion for activity gene gene799 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04010 UM146_RS04015 UM146_03890 UM146_RS04015 797290 798195 + GTPase Era gene gene800 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04015 UM146_RS04020 UM146_03895 recO recO 798207 798935 + DNA repair protein RecO involved in DNA repair and RecFOR pathway recombination%3B RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA gene gene801 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04020 UM146_RS04025 UM146_03900 UM146_RS04025 798947 799678 + pyridoxine 5'-phosphate synthase involved in the de novo synthesis of pyridoxine (Vitamin B6) gene gene802 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04025 UM146_RS04030 UM146_03905 acpS acpS 799678 800058 + holo-ACP synthase Catalyzes the formation of holo-ACP%2C which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids gene gene803 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04030 UM146_RS04035 UM146_RS04035 UM146_RS04035 800330 800482 + hypothetical protein gene gene804 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04035 UM146_RS04040 UM146_RS04040 UM146_RS04040 800479 800559 + small toxic protein ShoB gene gene805 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04040 UM146_RS04045 UM146_03910 UM146_RS04045 800753 801013 - ferredoxin gene gene806 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04045 UM146_RS04050 UM146_03915 UM146_RS04050 801069 801917 - transcriptional regulator gene gene807 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04050 UM146_RS04055 UM146_03920 UM146_RS04055 802126 802761 + hypothetical protein gene gene808 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04055 UM146_RS04060 UM146_03925 UM146_RS04060 802819 803322 + tRNA-specific adenosine deaminase gene gene809 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04060 UM146_RS04065 UM146_03930 UM146_RS04065 803319 804875 - murein transglycosylase gene gene810 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04065 UM146_RS04070 UM146_03935 UM146_RS04070 805134 809021 + phosphoribosylformylglycinamidine synthase catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis gene gene811 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04070 UM146_RS04075 UM146_03940 UM146_RS04075 809597 811024 + two-component system sensor histidine kinase part of the GlrKR two-component signal transduction system involved in the regulation of glmY gene gene812 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04075 UM146_RS04080 UM146_03945 UM146_RS04080 811189 811902 + membrane protein gene gene813 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04080 UM146_RS04085 UM146_03950 UM146_RS04085 811892 813226 + transcriptional regulator with GlrK is part of a two-component signal transduction system regulating glmY gene gene814 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04085 UM146_RS04090 UM146_03955 UM146_RS04090 813287 813625 + nitrogen regulatory protein P-II 1 indirectly regulates nitrogen metabolism%3B at high nitrogen levels P-II prevents the phosphorylation of NR-I%2C the transcriptional activator of the glutamine synthetase gene (glnA)%3B at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA gene gene815 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04090 UM146_RS04095 UM146_03960 UM146_RS04095 813670 814860 - bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2 flavohemoprotein%3B catalyzes the formation of nitrate from nitric oxide%3B can also catalyze the reduction of dihydropteridine gene gene816 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04095 UM146_RS04100 UM146_03965 UM146_RS04100 815188 816441 + serine hydroxymethyltransferase gene gene817 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04100 UM146_RS04105 UM146_03970 UM146_RS04105 816505 817698 - hypothetical protein gene gene818 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04105 UM146_RS04110 UM146_03975 UM146_RS04110 817816 821097 + hypothetical protein gene gene819 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04110 UM146_RS04115 UM146_03980 UM146_RS04115 821194 822177 + sugar ABC transporter substrate-binding protein gene gene820 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04115 UM146_RS04120 UM146_03985 UM146_RS04120 822200 823711 + heme ABC transporter ATP-binding protein gene gene821 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04120 UM146_RS04125 UM146_03990 UM146_RS04125 823736 824734 + sugar ABC transporter permease gene gene822 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04125 UM146_RS04130 UM146_03995 UM146_RS04130 824800 825861 + Zn-dependent NAD(P)-binding oxidoreductase gene gene823 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04130 UM146_RS04135 UM146_04000 UM146_RS04135 825873 826745 + hypothetical protein gene gene824 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04135 UM146_RS04140 UM146_04005 UM146_RS04140 826905 827327 - membrane protein gene gene825 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04140 UM146_RS04145 UM146_04010 UM146_RS04145 827696 828835 + 3-phenylpropionic acid MFS transporter transporter of 3-phenylpropionate across the inner membrane%3B member of the major facilitator superfamily of transporters gene gene826 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04145 UM146_RS04150 UM146_RS04150 UM146_RS04150 828943 830132 - stationary phase inducible protein CsiE gene gene827 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04150 UM146_RS04155 UM146_04030 UM146_RS04155 830302 831156 - hypothetical protein gene gene828 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04155 UM146_RS04160 UM146_04035 UM146_RS04160 831301 832104 - inositol-1-monophosphatase gene gene829 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04160 UM146_RS04165 UM146_04040 UM146_RS04165 832223 832963 + tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ catalyzes the fromation of 2'O-methylated cytidine or 2'O-methylated uridine at position 32 in tRNA gene gene830 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04165 UM146_RS04170 UM146_04045 UM146_RS04170 833233 833721 + Fe-S cluster assembly transcriptional regulator IscR regulates the expression of the iscRSUA operon gene gene831 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04170 UM146_RS04175 UM146_04050 UM146_RS04175 833833 835047 + cysteine desulfurase IscS catalyzes the removal of elemental sulfur from cysteine to produce alanine%3B involved in NAD biosynthesis gene gene832 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04175 UM146_RS04180 UM146_04055 UM146_RS04180 835075 835461 + Fe-S cluster assembly scaffold IscU gene gene833 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04180 UM146_RS04185 UM146_04060 iscA iscA 835478 835801 + iron-binding protein forms iron-sulfur clusters of ferredoxin [2FE-2S]%3B binds iron in the presence of the thioredoxin reductase system%3B forms homodimers and tetramers%3B similar to SufA protein gene gene834 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04185 UM146_RS04190 UM146_04065 hscB hscB 835897 836412 + co-chaperone protein HscB J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone%3B may function in biogenesis of iron-sulfur proteins gene gene835 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04190 UM146_RS04195 UM146_04070 hscA hscA 836429 838279 + chaperone protein HscA involved in the maturation of iron-sulfur cluster-containing proteins gene gene836 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04195 UM146_RS04200 UM146_04075 UM146_RS04200 838281 838616 + (2Fe-2S) ferredoxin gene gene837 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04200 UM146_RS04205 UM146_04080 UM146_RS04205 838628 838828 + protein IscX gene gene838 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04205 UM146_RS04210 UM146_04085 UM146_RS04210 838887 840170 + peptidase B catalyzes the removal of an N-terminal amino acid from a peptide or arylamide gene gene839 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04210 UM146_RS04215 UM146_04090 UM146_RS04215 840312 841088 + protein SseB enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I gene gene840 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04215 UM146_RS04220 UM146_04095 sseA sseA 841582 842427 - 3-mercaptopyruvate sulfurtransferase catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds gene gene841 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04220 UM146_RS04225 UM146_04100 UM146_RS04225 842634 847595 + hypothetical protein gene gene842 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04225 UM146_RS04230 UM146_RS04230 UM146_RS04230 847596 849909 + penicillin-binding protein 1C penicillin-insensitive transglycosylase/transpeptidase gene gene843 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04230 UM146_RS04235 UM146_04115 UM146_RS04235 850058 850489 + nucleoside diphosphate kinase catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate gene gene844 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04235 UM146_RS04240 UM146_04120 UM146_RS04240 850639 851793 + 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 23S rRNA m2A2503 methyltransferase%3B methylates the C2 position of the A2530 nucleotide in 23S rRNA%3B may be involved in antibiotic resistance gene gene845 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04240 UM146_RS04245 UM146_04125 UM146_RS04245 852078 853085 + cytoskeleton protein RodZ gene gene846 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04245 UM146_RS04250 UM146_04130 UM146_RS04250 853112 854230 + 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin) gene gene847 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04250 UM146_RS04255 UM146_04135 hisS hisS 854341 855615 + histidine--tRNA ligase catalyzes a two-step reaction%2C first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B class II aminoacyl-tRNA synthetase%3B forms homodimers%3B some organisms have a paralogous gene%2C hisZ%2C that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG gene gene848 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04255 UM146_RS04260 UM146_04140 UM146_RS04260 855633 856253 + membrane protein gene gene849 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04260 UM146_RS04265 UM146_04145 UM146_RS04265 856264 857442 + outer membrane biogenesis protein BamB gene gene850 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04265 UM146_RS04270 UM146_04150 UM146_RS04270 857560 859032 + GTPase Der gene gene851 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04270 UM146_RS04275 UM146_04155 UM146_RS04275 859095 859310 + hypothetical protein gene gene852 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04275 UM146_RS04280 UM146_04160 UM146_RS04280 859519 861723 + intimin involved in invasion of epithelial cells gene gene853 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04280 UM146_RS04285 UM146_04165 UM146_RS04285 861778 862755 + hypothetical protein gene gene854 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04285 UM146_RS04290 UM146_04170 UM146_RS04290 862876 870927 + hypothetical protein gene gene855 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04290 UM146_RS04295 UM146_04175 xseA xseA 870996 872372 - exodeoxyribonuclease 7 large subunit bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides gene gene856 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04295 UM146_RS04300 UM146_04180 UM146_RS04300 872534 874000 + inosine-5-monophosphate dehydrogenase gene gene857 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04300 UM146_RS04305 UM146_04185 guaA guaA 874069 875646 + GMP synthase [glutamine-hydrolyzing] contains glutamine-hydrolyzing domain and glutamine amidotransferase%3B GMP-binding domain%3B functions to produce GMP from XMP in the IMP pathway gene gene858 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04305 UM146_RS04310 UM146_04190 UM146_RS04310 875740 876279 - hypothetical protein gene gene859 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04310 UM146_RS04315 UM146_04195 UM146_RS04315 876295 876810 - membrane protein gene gene860 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04315 UM146_RS04320 UM146_04200 UM146_RS04320 877124 877315 - hypothetical protein gene gene861 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04320 UM146_RS04325 UM146_04205 UM146_RS04325 877333 877485 + hypothetical protein gene gene862 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04325 UM146_RS04330 UM146_04210 UM146_RS04330 877667 879910 + cyclic di-GMP phosphodiesterase gene gene863 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04330 UM146_RS04335 UM146_04215 UM146_RS04335 879949 881490 - exopolyphosphatase gene gene864 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04335 UM146_RS04340 UM146_04220 UM146_RS04340 881495 883561 - polyphosphate kinase gene gene865 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04340 UM146_RS04345 UM146_04225 purN purN 883733 884371 - phosphoribosylglycinamide formyltransferase glycinamide ribonucleotide transformylase%3B GAR Tfase%3B catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate%3B PurN requires formyl folate for the reaction unlike PurT which uses formate gene gene866 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04345 UM146_RS04350 UM146_04230 UM146_RS04350 884371 885408 - phosphoribosylformylglycinamidine cyclo-ligase catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis gene gene867 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04350 UM146_RS04355 UM146_04235 upp upp 885732 886358 + uracil phosphoribosyltransferase Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate gene gene868 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04355 UM146_RS04360 UM146_04240 UM146_RS04360 886445 887734 + uracil transporter gene gene869 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04360 UM146_RS04365 UM146_04245 UM146_RS04365 887853 888530 + DnaA regulatory inactivator Hda controls initiation of DNA replication by inhibiting re-initiation of replication%2C promotes hydrolysis of DnaA-bound ATP gene gene870 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04365 UM146_RS04370 UM146_04250 UM146_RS04370 888668 889027 - arsenate reductase gene gene871 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04370 UM146_RS04375 UM146_04255 UM146_RS04375 889048 890511 - hypothetical protein gene gene872 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04375 UM146_RS04380 UM146_04260 UM146_RS04380 890724 891785 + permease gene gene873 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04380 UM146_RS04385 UM146_04265 bcp bcp 891884 892354 - peroxiredoxin bacterioferritin comigratory protein%3B thiol peroxidase%3B thioredoxin-dependent%3B hydroperoxide peroxidase%3B in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide%3B contains an active site cysteine gene gene874 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04385 UM146_RS04390 UM146_04270 gcvR gcvR 892354 892926 - glycine cleavage system transcriptional regulator negative transcriptional regulator of the gcvTHP operon gene gene875 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04390 UM146_RS04395 UM146_04275 UM146_RS04395 893071 893949 + 4-hydroxy-tetrahydrodipicolinate synthase gene gene876 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04395 UM146_RS04400 UM146_04280 UM146_RS04400 893966 895000 + lipoprotein gene gene877 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04400 UM146_RS04405 UM146_RS04405 UM146_RS04405 894911 895141 - hypothetical protein gene gene878 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04405 UM146_RS04410 UM146_04285 UM146_RS04410 895213 895926 + phosphoribosylaminoimidazole-succinocarboxamide synthase catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis%3B SAICAR synthase gene gene879 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04410 UM146_RS04415 UM146_04290 UM146_RS04415 896094 896957 + hypothetical protein gene gene880 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04415 UM146_RS04420 UM146_04295 UM146_RS04420 896972 898987 + methionine tRNA cytidine acetyltransferase cetylates the wobble base C34 of the elongation-specific methionine tRNA gene gene881 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04420 UM146_RS04425 UM146_04300 UM146_RS04425 899061 899759 + hydrolase gene gene882 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04425 UM146_RS04430 UM146_04305 UM146_RS04430 899840 900040 - membrane protein gene gene883 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04430 UM146_RS04435 UM146_04310 UM146_RS04435 900068 901195 - succinyl-diaminopimelate desuccinylase gene gene884 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04435 UM146_RS04440 UM146_04315 UM146_RS04440 901199 901555 - reductase gene gene885 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04440 UM146_RS04445 UM146_RS04445 UM146_RS04445 901828 902007 - hypothetical protein gene gene886 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04445 UM146_RS04450 UM146_04320 UM146_RS04450 902094 905207 - multidrug efflux RND transporter permease subunit gene gene887 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04450 UM146_RS04455 UM146_RS04455 UM146_RS04455 905371 907070 - nitrate/nitrite sensor protein NarQ gene gene888 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04455 UM146_RS04460 UM146_04335 UM146_RS04460 907275 909254 + oxidoreductase Fe-S-binding subunit unknown function%3B in E. coli the aegA gene is regulated by Fnr%2C NarXL%2C and NarQ (but not ArcA)%2C induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) gene gene889 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04460 UM146_RS04465 UM146_04340 UM146_RS04465 909322 909897 + GDP-mannose pyrophosphatase NudK gene gene890 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04465 UM146_RS04470 UM146_04345 UM146_RS04470 910067 911065 + hypothetical protein gene gene891 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04470 UM146_RS04475 UM146_04350 UM146_RS04475 911142 913145 - transketolase catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate%3B can transfer ketol groups between several groups%3B in Escherichia coli there are two tkt genes%2C tktA expressed during exponential growth and the tktB during stationary phase gene gene892 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04475 UM146_RS04480 UM146_04355 UM146_RS04480 913165 914115 - transaldolase A gene gene893 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04480 UM146_RS04485 UM146_04360 UM146_RS04485 914404 916683 + malic enzyme NADP-dependent%3B catalyzes the oxidative decarboxylation of malate to form pyruvate%3B decarboxylates oxaloacetate gene gene894 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04485 UM146_RS04490 UM146_04365 UM146_RS04490 916976 917311 + carboxysome shell protein ethanolamine utilization protein%3B involved in the degredation of ethanolamine gene gene895 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04490 UM146_RS04495 UM146_04370 UM146_RS04495 917324 917803 + ethanolamine utilization protein EutP gene gene896 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04495 UM146_RS04500 UM146_04375 UM146_RS04500 917778 918479 + ethanolamine utilization protein EutQ gene gene897 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04500 UM146_RS04505 UM146_04380 UM146_RS04505 918476 919279 + ethanolamine utilization cobalamin adenosyltransferase catalyzes the conversion of cob(I)yrinic acid a%2Cc-diamide to adenosylcob(III)yrinic acid a%2Cc-diamide gene gene898 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04505 UM146_RS04510 UM146_04385 UM146_RS04510 919276 920292 + phosphotransacetylase gene gene899 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04510 UM146_RS04515 UM146_04390 UM146_RS04515 920331 920624 + ethanolamine utilization protein EutM ethanolamine utilization protein%3B involved in the degredation of ethanolamine gene gene900 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04515 UM146_RS04520 UM146_04395 UM146_RS04520 920731 921018 + ethanolamine utilization protein EutN gene gene901 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04520 UM146_RS04525 UM146_04400 UM146_RS04525 921030 922433 + aldehyde dehydrogenase ethanolamine utilization protein%3B catalyzes the formation of acetyl-CoA from acetaldehyde gene gene902 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04525 UM146_RS04530 UM146_04405 UM146_RS04530 922444 923280 + ethanolamine utilization protein EutJ possible chaperonin%3B may be involved in the assembly of the carboxysome gene gene903 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04530 UM146_RS04535 UM146_04410 UM146_RS04535 923270 924457 + ethanol dehydrogenase aldehyde reductase%3B catalyzes the conversion of acetaldehyde to ethanol gene gene904 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04535 UM146_RS04540 UM146_04415 UM146_RS04540 924674 925900 + ethanolamine utilization protein EutH may be involved in the transport of ethanolamine gene gene905 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04540 UM146_RS04545 UM146_04420 eutA eutA 925897 927300 + ethanolamine utilization protein EutA ethanolamine utilization protein EutA gene gene906 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04545 UM146_RS04550 UM146_04425 UM146_RS04550 927312 928673 + ethanolamine ammonia lyase large subunit with EutC catalyzes the formation of acetaldehyde and ammonia from ethanolamine gene gene907 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04550 UM146_RS04555 UM146_04430 UM146_RS04555 928694 929581 + ethanolamine ammonia-lyase light chain catalyzes the formation of acetaldehyde from ethanolamine gene gene908 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04555 UM146_RS04560 UM146_04435 UM146_RS04560 929591 930250 + ethanolamine utilization protein EutL carboxysome structural protein involved in ethanolamine utilization gene gene909 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04560 UM146_RS04565 UM146_04440 UM146_RS04565 930263 930763 + ethanolamine utilization protein EutK ethanolamine utilization protein%3B involved in the degredation of ethanolamine gene gene910 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04565 UM146_RS04570 UM146_04445 UM146_RS04570 930809 931861 + transcriptional regulator activates the transcription of the ethanolamine utilization operon gene gene911 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04570 UM146_RS04575 UM146_04450 UM146_RS04575 931867 932766 - coproporphyrinogen III oxidase catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis gene gene912 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04575 UM146_RS04580 UM146_04455 UM146_RS04580 932770 933639 - N-acetylmuramoyl-L-alanine amidase gene gene913 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04580 UM146_RS04585 UM146_04460 UM146_RS04585 933853 934278 + acetyltransferase YpeA gene gene914 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04585 UM146_RS04590 UM146_04465 UM146_RS04590 934265 934714 + membrane protein gene gene915 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04590 UM146_RS04595 UM146_04475 UM146_RS04595 934775 935350 + RpoE-regulated lipoprotein gene gene916 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04595 UM146_RS04600 UM146_04480 UM146_RS04600 935447 936346 + deferrochelatase/peroxidase gene gene917 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04600 UM146_RS04605 UM146_04485 murP murP 936524 937948 - PTS N-acetylmuramic acid EIIBC component belongs to PEP-dependent PTS system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel%3B requires crr-encoded enzyme IIA-glucose component gene gene918 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04605 UM146_RS04610 UM146_04490 UM146_RS04610 937952 938848 - N-acetylmuramic acid 6-phosphate etherase catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate%3B involved in MurNAc dissimilation pathway gene gene919 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04610 UM146_RS04615 UM146_04495 UM146_RS04615 939128 939919 + short-chain dehydrogenase gene gene920 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04615 UM146_RS04620 UM146_04500 UM146_RS04620 940077 941093 + thiosulfate transporter subunit gene gene921 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04620 UM146_RS04625 UM146_04505 UM146_RS04625 941093 941926 + sulfate/thiosulfate transporter subunit gene gene922 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04625 UM146_RS04630 UM146_04510 cysW cysW 941926 942801 + sulfate ABC transporter permease Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import gene gene923 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04630 UM146_RS04635 UM146_04515 UM146_RS04635 942791 943888 + sulfate/thiosulfate import ATP-binding protein CysA gene gene924 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04635 UM146_RS04640 UM146_04520 cysM cysM 944023 944934 + cysteine synthase B catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide gene gene925 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04640 UM146_RS04645 UM146_04525 UM146_RS04645 944937 945305 - hypothetical protein gene gene926 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04645 UM146_RS04650 UM146_04530 pdxK pdxK 945410 946261 + pyridoxine kinase catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal gene gene927 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04650 UM146_RS04655 UM146_04535 UM146_RS04655 946304 946813 - glucose-specific phosphotransferase enzyme IIA component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene928 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04655 UM146_RS04660 UM146_04540 UM146_RS04660 946854 948581 - phosphoenolpyruvate-protein phosphotransferase Phosphotransferase system%2C enzyme I%3B transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein%3B part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active-transport system gene gene929 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04660 UM146_RS04665 UM146_04545 UM146_RS04665 948626 948883 - phosphocarrier protein HPr gene gene930 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04665 UM146_RS04670 UM146_04550 UM146_RS04670 949267 950238 - cysteine synthase A gene gene931 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04670 UM146_RS04675 UM146_04555 UM146_RS04675 950423 951184 - sulfate transporter CysZ gene gene932 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04675 UM146_RS04680 UM146_04560 UM146_RS04680 951414 952412 + Cell division protein ZipA homolog interacts with cell division protein FitsZ and may be required to anchor septal ring structure gene gene933 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04680 UM146_RS04685 UM146_04565 ligA ligA 952483 954498 + DNA ligase this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction%3B essential for DNA replication and repair of damaged DNA%3B similar to ligase LigB gene gene934 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04685 UM146_RS04690 UM146_04570 UM146_RS04690 954500 954718 + DUF3820 domain-containing protein gene gene935 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04690 UM146_RS04695 UM146_04575 UM146_RS04695 954715 955713 - hypothetical protein gene gene936 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04695 UM146_RS04700 UM146_04580 UM146_RS04700 955803 956729 + LysR family transcriptional regulator gene gene937 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04700 UM146_RS04705 UM146_04585 UM146_RS04705 956768 957532 - membrane protein gene gene938 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04705 UM146_RS04710 UM146_04590 UM146_RS04710 957781 958614 + purine nucleoside phosphorylase gene gene939 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04710 UM146_RS04715 UM146_04595 UM146_RS04715 958675 959931 + nucleoside permease gene gene940 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04715 UM146_RS04720 UM146_04600 UM146_RS04720 959984 960142 + hypothetical protein gene gene941 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04720 UM146_RS04725 UM146_04605 UM146_RS04725 960183 961067 + transcriptional regulator gene gene942 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04725 UM146_RS04730 UM146_t23845 UM146_RS04730 961178 961253 - tRNA-Lys tRNA gene943 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04730 UM146_RS04735 UM146_t23847 UM146_RS04735 961258 961333 - tRNA-Val tRNA gene944 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04735 UM146_RS04740 UM146_t23849 UM146_RS04740 961381 961456 - tRNA-Val tRNA gene945 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04740 UM146_RS04745 UM146_t23851 UM146_RS04745 961501 961576 - tRNA-Val tRNA gene946 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04745 UM146_RS04750 UM146_04610 gltX gltX 961835 963250 + glutamate--tRNA ligase catalyzes a two-step reaction%2C first charging an glutamate molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B contains discriminating and non-discriminating subtypes gene gene947 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04750 UM146_RS04755 UM146_04615 UM146_RS04755 963301 963693 - hypothetical protein gene gene948 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04755 UM146_RS04760 UM146_04620 UM146_RS04760 963695 964039 - DUF1323 family DNA-binding protein gene gene949 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04760 UM146_RS04765 UM146_t23853 UM146_RS04765 964275 964350 + tRNA-Ala tRNA gene950 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04765 UM146_RS04770 UM146_t23855 UM146_RS04770 964390 964465 + tRNA-Ala tRNA gene951 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04770 UM146_RS04775 UM146_04625 UM146_RS04775 964672 966861 + outer membrane protein gene gene952 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04775 UM146_RS04780 UM146_04630 UM146_RS04780 966904 968105 - nucleoside permease gene gene953 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04780 UM146_RS04785 UM146_04640 UM146_RS04785 968441 969679 + divalent metal cation transporter MntH gene gene954 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04785 UM146_RS04790 UM146_04645 UM146_RS04790 969738 969899 - hypothetical protein gene gene955 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04790 UM146_RS04795 UM146_04650 UM146_RS04795 969820 970146 - hypothetical protein gene gene956 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04795 UM146_RS04800 UM146_04655 UM146_RS04800 970261 971517 - ion channel protein gene gene957 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04800 UM146_RS04805 UM146_04660 glk glk 971721 972686 + glucokinase catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate gene gene958 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04805 UM146_RS04810 UM146_04665 UM146_RS04810 972905 973231 + fructose-like phosphotransferase enzyme IIB component 1 gene gene959 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04810 UM146_RS04815 UM146_04670 UM146_RS04815 973253 974500 + PTS fructose transporter subunit IIC gene gene960 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04815 UM146_RS04820 UM146_04675 UM146_RS04820 974516 975601 + aminopeptidase Xaa-Pro aminopeptidase%3B limited methionine aminopeptidase gene gene961 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04820 UM146_RS04825 UM146_04680 UM146_RS04825 975601 976638 + exoaminopeptidase metalloprotein gene gene962 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04825 UM146_RS04830 UM146_04685 UM146_RS04830 976663 979158 + PTS fructose transporter subunit IIA gene gene963 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04830 UM146_RS04835 UM146_04690 UM146_RS04835 979161 980018 - AraC family transcriptional regulator gene gene964 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04835 UM146_RS04840 UM146_04695 UM146_RS04840 980031 980768 - two-component system response regulator gene gene965 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04840 UM146_RS04845 UM146_04700 UM146_RS04845 980783 982480 - membrane protein gene gene966 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04845 UM146_RS04850 UM146_04705 UM146_RS04850 982857 984095 + glutamate--pyruvate aminotransferase AlaC gene gene967 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04850 UM146_RS04855 UM146_04710 UM146_RS04855 984587 985507 - lipid A biosynthesis palmitoleoyl acyltransferase Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock gene gene968 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04855 UM146_RS04860 UM146_04715 UM146_RS04860 985860 986102 + hypothetical protein gene gene969 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04860 UM146_RS04865 UM146_RS04865 UM146_RS04865 986057 986203 + hypothetical protein gene gene970 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04865 UM146_RS04870 UM146_04720 UM146_RS04870 986179 986454 - hypothetical protein gene gene971 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04870 UM146_RS04875 UM146_04725 UM146_RS04875 986750 987385 + hypothetical protein gene gene972 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04875 UM146_RS04880 UM146_04730 UM146_RS04880 987897 989147 + formyl-CoA--oxalate CoA-transferase catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA gene gene973 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04880 UM146_RS04885 UM146_04735 UM146_RS04885 989201 990895 + oxalyl-CoA decarboxylase catalyzes the formation of formyl-CoA from oxalyl-CoA gene gene974 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04885 UM146_RS04890 UM146_04740 UM146_RS04890 990965 991909 + transporter member of the AEC family of auxin efflux transporters%3B unknown function gene gene975 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04890 UM146_RS04895 UM146_04745 UM146_RS04895 991983 993128 + CoA-transferase gene gene976 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04895 UM146_RS04900 UM146_04750 UM146_RS04900 993184 996567 - sensor histidine kinase gene gene977 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04900 UM146_RS04905 UM146_04755 UM146_RS04905 996782 997396 - positive transcription regulator EvgA response regulator in two-component regulatory system with EvgS%3B phosphorylated EvgA activates ompC%2C emrKY%2C gadABC%2C hdeAB and others genes%3B involved in acid resistance%2C osmotic adaption%2C and drug resistance gene gene978 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04905 UM146_RS04910 UM146_04760 UM146_RS04910 997811 998974 + multidrug transporter with ErmA and TolC forms a multidrug efflux system gene gene979 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04910 UM146_RS04915 UM146_04765 emrB emrB 998974 1000512 + multidrug resistance protein EmrY multidrug MFS transporte%3B with EmrA is involved in resistance to hydrophobic antibiotics such as nalidixic acid gene gene980 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04915 UM146_RS04920 UM146_04770 UM146_RS04920 1000620 1001948 - D-serine dehydratase 1 catalyzes the formation of pyruvate from serine gene gene981 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04920 UM146_RS04925 UM146_04775 UM146_RS04925 1001966 1003303 - permease gene gene982 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04925 UM146_RS04930 UM146_04780 UM146_RS04930 1003521 1004456 + transcriptional regulator regulates the synthesis and expression of the dsdXA operon and dadA gene gene gene983 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04930 UM146_RS04935 UM146_04785 UM146_RS04935 1004643 1004843 - transcriptional regulator gene gene984 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04935 UM146_RS04940 UM146_RS04940 UM146_RS04940 1004900 1005067 - hypothetical protein gene gene985 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04940 UM146_RS04945 UM146_04790 UM146_RS04945 1005140 1005424 - RNA-binding protein gene gene986 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04945 UM146_RS04950 UM146_04795 UM146_RS04950 1005417 1005701 - hypothetical protein gene gene987 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04950 UM146_RS04955 UM146_04800 UM146_RS04955 1005701 1006273 - hypothetical protein gene gene988 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04955 UM146_RS04960 UM146_RS04960 UM146_RS04960 1006275 1006574 - hypothetical protein gene gene989 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04960 UM146_RS04965 UM146_04805 UM146_RS04965 1006571 1007089 - hypothetical protein gene gene990 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04965 UM146_RS04970 UM146_RS04970 UM146_RS04970 1007086 1007169 - hypothetical protein gene gene991 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04970 UM146_RS04975 UM146_04810 UM146_RS04975 1007184 1007480 - hypothetical protein gene gene992 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04975 UM146_RS04980 UM146_04815 UM146_RS04980 1007504 1007887 - hypothetical protein gene gene993 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04980 UM146_RS04985 UM146_04820 UM146_RS04985 1007887 1008492 - recombinase gene gene994 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04985 UM146_RS04990 UM146_RS04990 UM146_RS04990 1008503 1008628 - hypothetical protein gene gene995 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04990 UM146_RS04995 UM146_04825 UM146_RS04995 1008594 1008752 - hypothetical protein gene gene996 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS04995 UM146_RS05000 UM146_04830 UM146_RS05000 1008749 1008901 - protein kil gene gene997 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05000 UM146_RS05005 UM146_04835 UM146_RS05005 1008886 1009017 - Regulatory protein CIII gene gene998 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05005 UM146_RS05010 UM146_RS05010 UM146_RS05010 1009042 1010011 - cell envelope biogenesis protein TolA gene gene999 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05010 UM146_RS05015 UM146_04850 UM146_RS05015 1010201 1010623 - hypothetical protein gene gene1000 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05015 UM146_RS05020 UM146_04855 UM146_RS05020 1010681 1010881 - Restriction inhibitor protein ral gene gene1001 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05020 UM146_RS05025 UM146_04860 UM146_RS05025 1010960 1011259 - hypothetical protein gene gene1002 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05025 UM146_RS05030 UM146_04865 UM146_RS05030 1011780 1012430 - repressor gene gene1003 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05030 UM146_RS05035 UM146_04870 UM146_RS05035 1012511 1012696 + hypothetical protein gene gene1004 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05035 UM146_RS05040 UM146_04875 UM146_RS05040 1012805 1013098 + hypothetical protein gene gene1005 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05040 UM146_RS05045 UM146_04880 UM146_RS05045 1013121 1013393 + hypothetical protein gene gene1006 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05045 UM146_RS05050 UM146_04885 UM146_RS05050 1013456 1014343 + replication protein gene gene1007 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05050 UM146_RS05055 UM146_04890 UM146_RS05055 1014340 1015716 + DNA helicase gene gene1008 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05055 UM146_RS05060 UM146_04895 UM146_RS05060 1015713 1015811 + histone H1 gene gene1009 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05060 UM146_RS05065 UM146_04900 UM146_RS05065 1015991 1016431 + hypothetical protein gene gene1010 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05065 UM146_RS05070 UM146_04905 UM146_RS05070 1016428 1016604 + protein ninE gene gene1011 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05070 UM146_RS05075 UM146_04910 UM146_RS05075 1016607 1016954 + hypothetical protein gene gene1012 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05075 UM146_RS05080 UM146_04915 UM146_RS05080 1016947 1017123 + protein ninF gene gene1013 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05080 UM146_RS05085 UM146_04920 UM146_RS05085 1017116 1017838 + DNA-binding protein gene gene1014 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05085 UM146_RS05090 UM146_04925 UM146_RS05090 1017838 1018128 + hypothetical protein gene gene1015 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05090 UM146_RS05095 UM146_04930 UM146_RS05095 1018125 1018487 + endodeoxyribonuclease gene gene1016 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05095 UM146_RS05100 UM146_04935 UM146_RS05100 1018484 1018672 + protein ninH gene gene1017 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05100 UM146_RS05105 UM146_04940 UM146_RS05105 1018669 1019187 + late gene antiterminator protein gene gene1018 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05105 UM146_RS05110 UM146_04945 UM146_RS05110 1019784 1020107 + holin gene gene1019 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05110 UM146_RS05115 UM146_04950 UM146_RS05115 1020091 1020567 + lysozyme gene gene1020 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05115 UM146_RS05120 UM146_04955 UM146_RS05120 1020564 1021001 + endopeptidase gene gene1021 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05120 UM146_RS05125 UM146_04960 UM146_RS05125 1020989 1021141 + hypothetical protein gene gene1022 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05125 UM146_RS05130 UM146_04965 UM146_RS05130 1021347 1021889 + Rha family transcriptional regulator gene gene1023 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05130 UM146_RS05135 UM146_04970 UM146_RS05135 1022117 1022359 + hypothetical protein gene gene1024 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05135 UM146_RS05140 UM146_04975 UM146_RS05140 1022362 1022802 + terminase gene gene1025 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05140 UM146_RS05145 UM146_04980 UM146_RS05145 1022799 1024214 + terminase gene gene1026 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05145 UM146_RS05150 UM146_04985 UM146_RS05150 1024216 1026414 + portal protein gene gene1027 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05150 UM146_RS05155 UM146_04990 UM146_RS05155 1026505 1027398 + scaffold protein gene gene1028 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05155 UM146_RS05160 UM146_04995 UM146_RS05160 1027417 1028670 + coat protein gene gene1029 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05160 UM146_RS05165 UM146_05000 UM146_RS05165 1028712 1028900 + hypothetical protein gene gene1030 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05165 UM146_RS05170 UM146_05005 UM146_RS05170 1028881 1029342 + head DNA stabilization protein gene gene1031 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05170 UM146_RS05175 UM146_05010 UM146_RS05175 1029352 1030770 + Packaged DNA stabilization protein gp10 gene gene1032 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05175 UM146_RS05180 UM146_05015 UM146_RS05180 1030770 1031471 + tail protein gene gene1033 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05180 UM146_RS05185 UM146_05020 UM146_RS05185 1031471 1031926 + hypothetical protein gene gene1034 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05185 UM146_RS05190 UM146_05025 UM146_RS05190 1031929 1032621 + DNA transfer protein gene gene1035 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05190 UM146_RS05195 UM146_05030 UM146_RS05195 1032632 1033981 + DNA injection protein gene gene1036 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05195 UM146_RS05200 UM146_05035 UM146_RS05200 1033981 1036140 + DNA transfer protein gene gene1037 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05200 UM146_RS05205 UM146_05040 UM146_RS05205 1036141 1036464 - hypothetical protein gene gene1038 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05205 UM146_RS05210 UM146_05045 UM146_RS05210 1036487 1036906 - hypothetical protein gene gene1039 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05210 UM146_RS05215 UM146_05050 UM146_RS05215 1036891 1037472 - hypothetical protein gene gene1040 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05215 UM146_RS05220 UM146_05055 UM146_RS05220 1037533 1037781 - hypothetical protein gene gene1041 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05220 UM146_RS05225 UM146_05060 UM146_RS05225 1037805 1038062 - DNA-binding protein gene gene1042 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05225 UM146_RS05230 UM146_05065 UM146_RS05230 1038168 1038308 + DNA-binding protein gene gene1043 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05230 UM146_RS05235 UM146_05070 UM146_RS05235 1038572 1039495 + antirepressor gene gene1044 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05235 UM146_RS05240 UM146_05075 UM146_RS05240 1039596 1042541 + peptidase S74 gene gene1045 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05240 UM146_RS05245 UM146_RS05245 UM146_RS05245 1042861 1043016 - hypothetical protein gene gene1046 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05245 UM146_RS05250 UM146_05080 UM146_RS05250 1043724 1044881 - hypothetical protein gene gene1047 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05250 UM146_RS05255 UM146_t23857 UM146_RS05255 1045043 1045117 - tRNA-Arg tRNA gene1048 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05255 UM146_RS05260 UM146_05085 UM146_RS05260 1045193 1046125 - membrane protein gene gene1049 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05260 UM146_RS05265 UM146_05090 UM146_RS05265 1046419 1047174 + membrane protein involved in maintaining OM lipid asymmetry gene gene1050 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05265 UM146_RS05270 UM146_05095 UM146_RS05270 1047232 1048572 - long-chain fatty acid outer membrane transporter gene gene1051 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05270 UM146_RS05275 UM146_05100 UM146_RS05275 1048944 1049228 + hypothetical protein gene gene1052 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05275 UM146_RS05280 UM146_05105 fadI fadI 1049409 1050719 + 3-ketoacyl-CoA thiolase FadI%3B fatty acid oxidation complex component beta%3B functions in a heterotetramer with FadJ%3B similar to FadA2B2 complex%3B functions in beta-oxidation of fatty acids during anaerobic growth gene gene1053 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05280 UM146_RS05285 UM146_05110 fadJ fadJ 1050719 1052863 + fatty acid oxidation complex subunit alpha multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase%3B catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA%3B exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI%3B similar to FadA2B2 complex%3B involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate gene gene1054 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05285 UM146_RS05290 UM146_05115 UM146_RS05290 1053065 1053550 + phosphohistidine phosphatase gene gene1055 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05290 UM146_RS05295 UM146_RS05295 UM146_RS05295 1054115 1054678 + fimbrial protein gene gene1056 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05295 UM146_RS05300 UM146_05125 UM146_RS05300 1054738 1057386 + fimbrial protein SteB gene gene1057 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05300 UM146_RS05305 UM146_05130 UM146_RS05305 1057406 1058158 + fimbrial protein StfD gene gene1058 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05305 UM146_RS05310 UM146_05135 UM146_RS05310 1058175 1058678 + hypothetical protein gene gene1059 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05310 UM146_RS05315 UM146_05140 UM146_RS05315 1058675 1059154 + fimbrial protein SteE gene gene1060 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05315 UM146_RS05320 UM146_05145 UM146_RS05320 1059151 1059678 + fimbrial protein gene gene1061 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05320 UM146_RS05325 UM146_RS05325 UM146_RS05325 1059680 1060522 + hypothetical protein gene gene1062 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05325 UM146_RS05330 UM146_RS05330 UM146_RS05330 1060569 1060817 - hypothetical protein gene gene1063 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05330 UM146_RS05335 UM146_05155 UM146_RS05335 1060842 1061393 - peptidase S10 gene gene1064 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05335 UM146_RS05340 UM146_05160 UM146_RS05340 1061559 1062491 + 50S ribosomal protein L3 glutamine methyltransferase involved in methylation of ribosomal protein L3 gene gene1065 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05340 UM146_RS05345 UM146_05165 UM146_RS05345 1062526 1063611 + chorismate synthase catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis gene gene1066 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05345 UM146_RS05350 UM146_05170 mepA mepA 1063615 1064439 + penicillin-insensitive murein endopeptidase D-alanyl-D-alanine endopeptidase%3B functions in hydrolyzing cell wall peptidoglycan%3B similar to LAS metallopeptidases%3B forms a dimer in periplasm gene gene1067 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05350 UM146_RS05355 UM146_05175 UM146_RS05355 1064439 1065248 + membrane protein gene gene1068 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05355 UM146_RS05360 UM146_05180 UM146_RS05360 1065248 1065796 + hypothetical protein gene gene1069 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05360 UM146_RS05365 UM146_05185 UM146_RS05365 1065830 1066108 + hypothetical protein gene gene1070 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05365 UM146_RS05370 UM146_05190 mnmC mnmC 1066229 1068235 - tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC 5-methylaminomethyl-2-thiouridine-forming enzyme methyltransferase/FAD-dependent demodification enzyme gene gene1071 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05370 UM146_RS05375 UM146_05195 UM146_RS05375 1068394 1069614 + 3-oxoacyl-ACP synthase I FabB%2C beta-Ketoacyl-ACP synthase I%2C KASI%3B catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP%3B required for the elongation of short-chain unsaturated acyl-ACP gene gene1072 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05375 UM146_RS05380 UM146_05200 UM146_RS05380 1069879 1071057 + transporter gene gene1073 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05380 UM146_RS05385 UM146_05205 flk flk 1071054 1072049 - flagella biosynthesis regulator in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system%3B lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm%3B inner membrane-anchored protein gene gene1074 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05385 UM146_RS05390 UM146_05210 UM146_RS05390 1072148 1073284 + erythronate-4-phosphate dehydrogenase catalyzes the formation of 3-hydroxy-2-oxo-4-phosphonooxybutanoate from erythronate-4-phosphate gene gene1075 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05390 UM146_RS05395 UM146_05215 UM146_RS05395 1073350 1074363 + semialdehyde dehydrogenase gene gene1076 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05395 UM146_RS05400 UM146_05220 truA truA 1074363 1075175 + tRNA pseudouridine synthase A mediates pseudouridylation (positions 38%2C 39%2C 40) at the tRNA anticodon region which contributes to the structural stability gene gene1077 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05400 UM146_RS05405 UM146_05225 UM146_RS05405 1075258 1075917 + membrane protein gene gene1078 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05405 UM146_RS05410 UM146_05230 UM146_RS05410 1076073 1076987 + acetyl-CoA carboxylase carboxyltransferase subunit beta catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%3B forms a tetramer of AccA2D2 subunits gene gene1079 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05410 UM146_RS05415 UM146_05235 UM146_RS05415 1077057 1078325 + bifunctional folylpolyglutamate synthase/ dihydrofolate synthase gene gene1080 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05415 UM146_RS05420 UM146_05240 UM146_RS05420 1078315 1078977 + cell division protein DedD gene gene1081 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05420 UM146_RS05425 UM146_05245 UM146_RS05425 1079509 1079997 + colicin V production protein membrane protein required for colicin V production gene gene1082 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05425 UM146_RS05430 UM146_05250 UM146_RS05430 1080034 1081551 + amidophosphoribosyltransferase Catalyzes first step of the de novo purine nucleotide biosynthetic pathway gene gene1083 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05430 UM146_RS05435 UM146_05255 UM146_RS05435 1081646 1082215 + 3-octaprenyl-4-hydroxybenzoate carboxy-lyase catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate gene gene1084 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05435 UM146_RS05440 UM146_05260 UM146_RS05440 1082481 1083263 + amino acid ABC transporter substrate-binding protein with HisPMQ is involved in the transport of histidine gene gene1085 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05440 UM146_RS05445 UM146_05265 UM146_RS05445 1083484 1084266 + zinc transporter with HisPMQ is involved in the transport of histidine gene gene1086 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05445 UM146_RS05450 UM146_05270 UM146_RS05450 1084356 1085042 + histidine ABC transporter permease with HisJMP is involved in the transport of histidine/lysine/arginine/ornithine gene gene1087 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05450 UM146_RS05455 UM146_05275 UM146_RS05455 1085039 1085755 + histidine ABC transporter permease with HisJPQ is involved in transport of histidine%2C lysine%2C arginine and ornithine gene gene1088 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05455 UM146_RS05460 UM146_05280 UM146_RS05460 1085763 1086536 + histidine transport ATP-binding protein HisP gene gene1089 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05460 UM146_RS05465 UM146_05285 UM146_RS05465 1086732 1087622 + transposase gene gene1090 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05465 UM146_RS05470 UM146_05290 UM146_RS05470 1087670 1088563 - epimerase gene gene1091 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05470 UM146_RS05475 UM146_05295 folX folX 1088584 1088946 - D-erythro-7%2C8-dihydroneopterin triphosphate epimerase catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate gene gene1092 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05475 UM146_RS05480 UM146_05300 UM146_RS05480 1089003 1089650 - GSH-dependent disulfide bond oxidoreductase gene gene1093 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05480 UM146_RS05485 UM146_05305 UM146_RS05485 1089786 1090430 + glutathione S-transferase catalyzes the formation of 2%2C4-dinitrophenyl-S-glutathione from 1-chloro-2%2C4-dinitrobenzene and glutathione gene gene1094 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05485 UM146_RS05490 UM146_05310 UM146_RS05490 1090486 1091037 + phosphodiesterase gene gene1095 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05490 UM146_RS05495 UM146_05315 UM146_RS05495 1091095 1091637 + NUDIX hydrolase gene gene1096 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05495 UM146_RS05500 UM146_05320 UM146_RS05500 1091670 1093190 - membrane protein gene gene1097 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05500 UM146_RS05505 UM146_05325 UM146_RS05505 1093380 1095524 - phosphate acetyltransferase catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate%3B when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate gene gene1098 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05505 UM146_RS05510 UM146_05330 UM146_RS05510 1095599 1096801 - acetate kinase AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation%3B utilizes magnesium and ATP%3B also involved in conversion of acetate to aceyl-CoA%3B also known to act on propionate gene gene1099 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05510 UM146_RS05515 UM146_05335 UM146_RS05515 1096939 1097070 + hypothetical protein gene gene1100 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05515 UM146_RS05520 UM146_05340 UM146_RS05520 1097139 1097594 + membrane protein gene gene1101 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05520 UM146_RS05525 UM146_05345 UM146_RS05525 1097676 1098170 + hypothetical protein gene gene1102 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05525 UM146_RS05530 UM146_05350 UM146_RS05530 1098181 1098831 + phosphatase gene gene1103 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05530 UM146_RS05535 UM146_05355 UM146_RS05535 1098918 1100750 + transporter gene gene1104 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05535 UM146_RS05540 UM146_05360 UM146_RS05540 1100809 1101408 - 5'-deoxynucleotidase YfbR gene gene1105 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05540 UM146_RS05545 UM146_05365 UM146_RS05545 1101492 1102709 - glutamate--pyruvate aminotransferase AlaA broad specificity%3B family IV%3B in Corynebacterium glutamicum this protein can use glutamate%2C 2-aminobutyrate%2C and aspartate as amino donors and pyruvate as the acceptor gene gene1106 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05545 UM146_RS05550 UM146_05370 UM146_RS05550 1103629 1104567 + transcriptional regulator involved in the regulation of genes involved in flagella synthesis%2C motility and chemotaxis gene gene1107 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05550 UM146_RS05555 UM146_05375 UM146_RS05555 1105196 1105639 + NADH-quinone oxidoreductase subunit A gene gene1108 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05555 UM146_RS05560 UM146_05380 UM146_RS05560 1105655 1106317 + NADH-quinone oxidoreductase subunit B gene gene1109 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05560 UM146_RS05565 UM146_05385 UM146_RS05565 1106423 1108213 + NADH-quinone oxidoreductase subunit C/D NuoCD%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron-sulfur (Fe-S) centers%2C to quinones in the respiratory chain%3B subunits NuoCD%2C E%2C F%2C and G constitute the peripheral sector of the complex%3B in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms gene gene1110 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05565 UM146_RS05570 UM146_05390 UM146_RS05570 1108216 1108716 + NADH-quinone oxidoreductase subunit E Catalyzes the transfer of electrons from NADH to quinone gene gene1111 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05570 UM146_RS05575 UM146_05395 UM146_RS05575 1108713 1110050 + NADH dehydrogenase subunit F part of NADH-ubiquinone oxidoreductase complex I%3B shuttles electrons from NADH%2C via FMN and iron-sulfur (Fe-S) centers%2C to quinones in the respiratory chain%3B NuoF is part of the soluble NADH dehydrogenase fragment%2C which represents the electron input part of NADH dehydrogenase gene gene1112 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05575 UM146_RS05580 UM146_05400 UM146_RS05580 1110103 1112829 + NADH dehydrogenase subunit G Catalyzes the transfer of electrons from NADH to quinone gene gene1113 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05580 UM146_RS05585 UM146_05405 UM146_RS05585 1112826 1113803 + NADH-quinone oxidoreductase subunit H gene gene1114 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05585 UM146_RS05590 UM146_05410 UM146_RS05590 1113818 1114360 + NADH-quinone oxidoreductase subunit I gene gene1115 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05590 UM146_RS05595 UM146_05415 UM146_RS05595 1114372 1114926 + NADH-quinone oxidoreductase subunit J Catalyzes the transfer of electrons from NADH to quinone gene gene1116 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05595 UM146_RS05600 UM146_05420 UM146_RS05600 1114923 1115225 + NADH-quinone oxidoreductase subunit K gene gene1117 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05600 UM146_RS05605 UM146_05425 UM146_RS05605 1115222 1117063 + NADH:ubiquinone oxidoreductase subunit L Catalyzes the transfer of electrons from NADH to ubiquinone gene gene1118 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05605 UM146_RS05610 UM146_05430 UM146_RS05610 1117227 1118756 + NADH:ubiquinone oxidoreductase subunit M gene gene1119 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05610 UM146_RS05615 UM146_05435 UM146_RS05615 1118763 1120220 + NADH-quinone oxidoreductase subunit N Catalyzes the transfer of electrons from NADH to quinone gene gene1120 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05615 UM146_RS05620 UM146_05440 UM146_RS05620 1120286 1120789 - hypothetical protein gene gene1121 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05620 UM146_RS05625 UM146_05445 UM146_RS05625 1120892 1121863 - hypothetical protein gene gene1122 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05625 UM146_RS05630 UM146_05450 UM146_RS05630 1122001 1123743 + hypothetical protein gene gene1123 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05630 UM146_RS05635 UM146_05455 UM146_RS05635 1123864 1124781 - hypothetical protein RNase BN%3B member of metallo-beta-lactamase family%3B the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase%3B in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not%3B associates with two zinc ions gene gene1124 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05635 UM146_RS05640 UM146_05460 UM146_RS05640 1124846 1125307 + acyltransferase gene gene1125 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05640 UM146_RS05645 UM146_05465 UM146_RS05645 1125362 1125667 + protein ElaB gene gene1126 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05645 UM146_RS05650 UM146_05470 UM146_RS05650 1125746 1127041 + isochorismate synthase gene gene1127 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05650 UM146_RS05655 UM146_05475 UM146_RS05655 1127130 1128800 + 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase SEPHCHC synthase%3B forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis gene gene1128 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05655 UM146_RS05660 UM146_05480 UM146_RS05660 1128797 1129555 + 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase catalyzes the formation of (1 R%2C6 R)-2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate in menaquinone biosynthesis gene gene1129 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05660 UM146_RS05665 UM146_05485 UM146_RS05665 1129570 1130427 + 1%2C4-dihydroxy-2-naphthoyl-CoA synthase catalyzes the formation of 1%2C4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA gene gene1130 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05665 UM146_RS05670 UM146_05490 UM146_RS05670 1130427 1131389 + o-succinylbenzoate synthase catalyzes the dehydration of 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate gene gene1131 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05670 UM146_RS05675 UM146_05495 UM146_RS05675 1131386 1132741 + O-succinylbenzoic acid--CoA ligase gene gene1132 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05675 UM146_RS05680 UM146_05500 UM146_RS05680 1132851 1133117 + signal transduction protein PmrD with BasR regulates genes involved in polymyxin resistance gene gene1133 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05680 UM146_RS05685 UM146_05505 UM146_RS05685 1133111 1133497 - 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF with ArnE is responsible for the transport of 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol from the cytoplasm to the periplasm gene gene1134 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05685 UM146_RS05690 UM146_05510 UM146_RS05690 1133497 1133832 - 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE with ArnE is involved in transporting 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol from the cytoplasmic face to the periplasmic face of the inner membrane gene gene1135 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05690 UM146_RS05695 UM146_05515 arnT arnT 1133829 1135481 - undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A gene gene1136 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05695 UM146_RS05700 UM146_05520 UM146_RS05700 1135481 1136371 - 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD catalyzes the formation of 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol from 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol gene gene1137 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05700 UM146_RS05705 UM146_05525 UM146_RS05705 1136368 1138350 - bifunctional polymyxin resistance protein ArnA Bifunctional polymyxin resistance arnA protein%3B catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose%3B active in certain mutant strains gene gene1138 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05705 UM146_RS05710 UM146_05530 UM146_RS05710 1138350 1139318 - undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate gene gene1139 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05710 UM146_RS05715 UM146_05535 UM146_RS05715 1139322 1140461 - UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose gene gene1140 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05715 UM146_RS05720 UM146_05540 UM146_RS05720 1140769 1141371 + LPS core heptose(II)-phosphate phosphatase catalyzes the of heptose(II) of the outer membrane lipopolysaccharide core gene gene1141 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05720 UM146_RS05725 UM146_05545 UM146_RS05725 1141410 1141835 - nucleoside triphosphatase catalyzes the hydrolysis of nucleoside triphosphates gene gene1142 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05725 UM146_RS05730 UM146_05550 UM146_RS05730 1142114 1142656 + membrane protein gene gene1143 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05730 UM146_RS05735 UM146_05555 UM146_RS05735 1142756 1143958 + hypothetical protein gene gene1144 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05735 UM146_RS05740 UM146_05560 UM146_RS05740 1144178 1144960 + IclR family transcriptional regulator gene gene1145 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05740 UM146_RS05745 UM146_05565 UM146_RS05745 1144975 1146180 + L-rhamnonate dehydratase catalyzes the formation of 2-keto-3-deoxy-L-rhamnonate from L-rhamnonate gene gene1146 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05745 UM146_RS05750 UM146_05570 UM146_RS05750 1146237 1147526 + MFS transporter gene gene1147 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05750 UM146_RS05755 UM146_05575 UM146_RS05755 1147544 1148347 + 2-keto-3-deoxy-L-rhamnonate aldolase catalyzes the retro-aldol cleavage of 2-keto-3-deoxy-L-rhamnonate to pyruvate and lactaldehyde gene gene1148 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05755 UM146_RS05760 UM146_05580 UM146_RS05760 1148388 1148573 - hypothetical protein gene gene1149 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05760 UM146_RS05765 UM146_05585 UM146_RS05765 1148586 1149545 - hypothetical protein gene gene1150 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05765 UM146_RS05770 UM146_05595 glpC glpC 1149738 1150928 - sn-glycerol-3-phosphate dehydrogenase subunit C anaerobic%3B with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate gene gene1151 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05770 UM146_RS05775 UM146_05600 UM146_RS05775 1150925 1152184 - anaerobic glycerol-3-phosphate dehydrogenase subunit B sn-glycerol-3-phosphate dehydrogenase (anaerobic)%3B catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate%3B part of GlpABC complex%3B presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters gene gene1152 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05775 UM146_RS05780 UM146_05605 glpA glpA 1152174 1153802 - sn-glycerol-3-phosphate dehydrogenase subunit A anaerobic%2C catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor gene gene1153 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05780 UM146_RS05785 UM146_05610 glpT glpT 1154075 1155433 + sn-glycerol-3-phosphate transporter catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell gene gene1154 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05785 UM146_RS05790 UM146_05615 glpQ glpQ 1155438 1156514 + glycerophosphodiester phosphodiesterase hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols%3B periplasmic gene gene1155 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05790 UM146_RS05795 UM146_05620 UM146_RS05795 1156717 1157367 + hypothetical protein gene gene1156 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05795 UM146_RS05800 UM146_05625 UM146_RS05800 1157421 1157675 - ferredoxin involved with ribonucleotide reductase diferric-tyrosyl radical (Y*) cofactor maintenance plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor%2C essential for nucleotide reduction catalyzed by ribonucleotide reductases gene gene1157 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05800 UM146_RS05805 UM146_05630 UM146_RS05805 1157675 1158805 - ribonucleotide-diphosphate reductase subunit beta B2 or R2 protein%3B type 1a enzyme%3B catalyzes the rate-limiting step in dNTP synthesis%3B converts nucleotides to deoxynucleotides%3B forms a homodimer and then a multimeric complex with NrdA gene gene1158 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05805 UM146_RS05810 UM146_05635 UM146_RS05810 1158952 1161237 - ribonucleotide-diphosphate reductase subunit alpha Catalyzes the rate-limiting step in dNTP synthesis gene gene1159 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05810 UM146_RS05815 UM146_RS05815 UM146_RS05815 1161305 1161448 - hypothetical protein gene gene1160 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05815 UM146_RS05820 UM146_05640 UM146_RS05820 1161919 1165677 + adhesin gene gene1161 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05820 UM146_RS05825 UM146_05645 UM146_RS05825 1165817 1166539 - ubiquinone biosynthesis O-methyltransferase Involved in ubiquinone biosynthesis gene gene1162 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05825 UM146_RS05830 UM146_05650 UM146_RS05830 1166686 1169313 + DNA gyrase subunit A gene gene1163 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05830 UM146_RS05835 UM146_05655 UM146_RS05835 1169462 1171150 + hypothetical protein gene gene1164 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05835 UM146_RS05840 UM146_05660 UM146_RS05840 1171147 1171770 + hypothetical protein gene gene1165 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05840 UM146_RS05845 UM146_05665 UM146_RS05845 1171794 1176308 + hypothetical protein gene gene1166 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05845 UM146_RS05850 UM146_05670 UM146_RS05850 1176309 1177958 + hypothetical protein gene gene1167 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05850 UM146_RS05855 UM146_05675 UM146_RS05855 1177963 1178739 + hypothetical protein gene gene1168 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05855 UM146_RS05860 UM146_05680 UM146_RS05860 1178813 1179997 - acetyl-CoA acetyltransferase Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase%2C catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation gene gene1169 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05860 UM146_RS05865 UM146_05685 UM146_RS05865 1180028 1181350 - short-chain fatty acids transporter gene gene1170 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05865 UM146_RS05870 UM146_05690 UM146_RS05870 1181347 1181997 - succinyl-CoA--3-ketoacid-CoA transferase gene gene1171 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05870 UM146_RS05875 UM146_05695 UM146_RS05875 1181997 1182659 - acetyl-CoA--acetoacetyl-CoA transferase subunit alpha gene gene1172 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05875 UM146_RS05880 UM146_05700 UM146_RS05880 1182855 1184240 - acetoacetate metabolism regulatory protein AtoC DNA-binding response regulator in two-component regulatory system with ZraS%3B response regulator/sigma54 interaction protein gene gene1173 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05880 UM146_RS05885 UM146_05705 UM146_RS05885 1184237 1186063 - PAS domain-containing two-component system sensor histidine kinase with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism gene gene1174 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05885 UM146_RS05890 UM146_05710 UM146_RS05890 1186230 1189079 + sensor histidine kinase gene gene1175 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05890 UM146_RS05895 UM146_05715 UM146_RS05895 1189279 1189929 - transcriptional regulator two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division%3B probably phosphorylated by RcsC or RcsF gene gene1176 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05895 UM146_RS05900 UM146_05720 UM146_RS05900 1189946 1192618 - phosphotransfer intermediate protein in two-component regulatory system with RcsBC gene gene1177 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05900 UM146_RS05905 UM146_05725 UM146_RS05905 1193356 1194447 + porin gene gene1178 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05905 UM146_RS05910 UM146_05730 UM146_RS05910 1194559 1195614 + thiamine biosynthesis lipoprotein ApbE catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine%3B involved in the maintenance and/or assembly of sulfur clusters%3B periplasmic lipoporotein anchored to the inner membrane%3B part of the thiamine pyrophosphate biosynthesis pathway gene gene1179 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05910 UM146_RS05915 UM146_05735 UM146_RS05915 1195688 1196752 + transcriptional regulator regulates genes involved in the repair of alkylated DNA%3B repairs DNA containing 6-O-methylguanine gene gene1180 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05915 UM146_RS05920 UM146_05740 UM146_RS05920 1196752 1197402 + alpha-ketoglutarate-dependent dioxygenase gene gene1181 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05920 UM146_RS05925 UM146_05745 UM146_RS05925 1197478 1199121 + multidrug ABC transporter ATP-binding protein efflux pump for the antibacterial peptide microcin J25 gene gene1182 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05925 UM146_RS05930 UM146_05750 UM146_RS05930 1199339 1200985 + malate:quinone oxidoreductase gene gene1183 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05930 UM146_RS05935 UM146_05755 UM146_RS05935 1201135 1201623 - ecotin serine protease inhibitor%2C inhibits trypsin and other proteases gene gene1184 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05935 UM146_RS05940 UM146_05760 UM146_RS05940 1201758 1201922 - hypothetical protein gene gene1185 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05940 UM146_RS05945 UM146_05765 UM146_RS05945 1202031 1202525 + ferredoxin-type protein NapF Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA. gene gene1186 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05945 UM146_RS05950 UM146_05770 UM146_RS05950 1202515 1202778 + nitrate reductase gene gene1187 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05950 UM146_RS05955 UM146_05775 UM146_RS05955 1202775 1205261 + periplasmic nitrate reductase periplasmic%3B catalytic subunit%3B with NapBC catalyzes the reduction of nitrate to nitrite%3B NapAB receives electrons from NapC gene gene1188 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05955 UM146_RS05960 UM146_05780 napG napG 1205268 1205963 + ferredoxin-type protein NapG part of NapHG quinol dehydrogenase%3B couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA%3B secreted by twin arginine translocation pathway gene gene1189 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05960 UM146_RS05965 UM146_05785 napH napH 1205950 1206813 + ferredoxin-type protein NapH part of NapHG quinol dehydrogenase%3B couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA gene gene1190 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05965 UM146_RS05970 UM146_05790 napB napB 1206810 1207259 + periplasmic nitrate reductase electron transfer subunit small subunit of periplasmic nitrate reductase%3B receives electrons from the membrane-bound NapC and passes them to NapA gene gene1191 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05970 UM146_RS05975 UM146_05795 UM146_RS05975 1207269 1207871 + cytochrome c-type protein NapC with NapABDFGH functions as a nitrate reductase%3B NapC functions as an electron shuttle between NapAB and NapGH or quinone gene gene1192 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05975 UM146_RS05980 UM146_05800 UM146_RS05980 1207890 1208507 + cytochrome C biogenesis protein CcmA gene gene1193 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05980 UM146_RS05985 UM146_05805 UM146_RS05985 1208507 1209166 + heme ABC transporter permease with CcmABCE is involved in the transport of protoheme IX%3B CcmB is required for the release of holoCcmE from CcmC gene gene1194 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05985 UM146_RS05990 UM146_05810 UM146_RS05990 1209208 1209945 + heme exporter protein C with CcmABDE is involved in the transport of protoheme IX%3B CcmC is required for heme transfer to CcmE gene gene1195 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05990 UM146_RS05995 UM146_05815 UM146_RS05995 1209942 1210151 + heme exporter protein D is invovled in heme transfer during cytochrome c biogenesis%3B acts to stabilize CcmC and CcmE gene gene1196 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS05995 UM146_RS06000 UM146_05820 UM146_RS06000 1210148 1210627 + cytochrome c-type biogenesis protein CcmE CycJ%3B periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes%3B requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome%3B part of the cytochrome c maturation system%3B periplasmic protein anchored to the inner membrane gene gene1197 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06000 UM146_RS06005 UM146_05825 UM146_RS06005 1210624 1212567 + heme lyase subunit CcmF cytochrome c-type biogenesis protein%3B required for the transfer of heme to apocytochrome c gene gene1198 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06005 UM146_RS06010 UM146_05830 UM146_RS06010 1212564 1213121 + thiol:disulfide interchange protein DsbE cytochrome c-type biogenesis thioredoxin%3B involved in the reduction of disulfide bonds to allow heme bonding gene gene1199 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06010 UM146_RS06015 UM146_05835 UM146_RS06015 1213118 1214170 + heme lyase subunit CcmH cytochrome c-type biogenesis protein%3B involved in the attachment of heme to cytochrome c gene gene1200 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06015 UM146_RS06020 UM146_05840 UM146_RS06020 1214205 1214852 - transcriptional regulator nitrate/nitrite response regulator NarP%3B NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems%3B represses expression of other anaerobic genes gene gene1201 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06020 UM146_RS06025 UM146_RS06025 UM146_RS06025 1214884 1215141 + hypothetical protein gene gene1202 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06025 UM146_RS06030 UM146_RS06030 UM146_RS06030 1215172 1215375 + membrane protein gene gene1203 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06030 UM146_RS06035 UM146_05845 UM146_RS06035 1215484 1215969 + autotransporter gene gene1204 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06035 UM146_RS06040 UM146_t23859 UM146_RS06040 1216071 1216147 - tRNA-Pro tRNA gene1205 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06040 UM146_RS06045 UM146_05850 UM146_RS06045 1216222 1217982 - hypothetical protein gene gene1206 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06045 UM146_RS06050 UM146_05855 UM146_RS06050 1218002 1218229 - hypothetical protein gene gene1207 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06050 UM146_RS06055 UM146_05860 UM146_RS06055 1218411 1219418 + nucleoid-associated protein gene gene1208 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06055 UM146_RS06060 UM146_05865 UM146_RS06060 1219557 1219841 - 50S ribosomal protein L25 gene gene1209 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06060 UM146_RS06065 UM146_05870 UM146_RS06065 1219966 1221726 - hypothetical protein gene gene1210 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06065 UM146_RS06070 UM146_05875 UM146_RS06070 1221876 1222571 + ribosomal small subunit pseudouridine synthase A catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA gene gene1211 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06070 UM146_RS06075 UM146_05880 UM146_RS06075 1222599 1223789 + Bcr/CflA family drug resistance efflux transporter Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance gene gene1212 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06075 UM146_RS06080 UM146_05885 UM146_RS06080 1224123 1224467 + hypothetical protein gene gene1213 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06080 UM146_RS06085 UM146_05890 UM146_RS06085 1224471 1226060 - microcin C ABC transporter ATP-binding protein YejF with YejAEF is involved in resistance to microcin C gene gene1214 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06085 UM146_RS06090 UM146_05895 UM146_RS06090 1226062 1227087 - ABC transporter permease part of the microcin C transport system gene gene1215 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06090 UM146_RS06095 UM146_05900 UM146_RS06095 1227087 1228181 - ABC transporter permease with YejAEF is involved in resistance to microcin C gene gene1216 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06095 UM146_RS06100 UM146_05905 UM146_RS06100 1228182 1229996 - peptide ABC transporter substrate-binding protein with YejBEF is involved in resistance to microcin C gene gene1217 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06100 UM146_RS06105 UM146_05910 UM146_RS06105 1230078 1231634 - phage resistance protein involved in resistance to the phages N4 and lambda gene gene1218 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06105 UM146_RS06110 UM146_05915 spr spr 1231815 1232381 - murein DD-endopeptidase MepS/Murein LD-carboxypeptidase mutational suppressor of prc thermosensitivity gene gene1219 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06110 UM146_RS06115 UM146_05920 UM146_RS06115 1232793 1233506 - lipid A 1-diphosphate synthase gene gene1220 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06115 UM146_RS06120 UM146_05925 UM146_RS06120 1233545 1234531 - hypothetical protein gene gene1221 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06120 UM146_RS06125 UM146_05930 UM146_RS06125 1234649 1236115 - D-mannonate oxidoreductase gene gene1222 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06125 UM146_RS06130 UM146_05935 UM146_RS06130 1236338 1236910 - elongation factor P-like protein Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro%2C suggesting its involvement in the formation of the first peptide bond of a protein gene gene1223 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06130 UM146_RS06135 UM146_05940 UM146_RS06135 1237065 1237319 + hypothetical protein gene gene1224 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06135 UM146_RS06140 UM146_05945 UM146_RS06140 1237316 1238497 - sugar transporter gene gene1225 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06140 UM146_RS06145 UM146_05950 UM146_RS06145 1238864 1239994 + multiphosphoryl transfer protein phosphoenolpyruvate (PEP)-dependent%2C sugar transporting phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIA is phosphorylated by phospho-HPr which then transfers the phosphoryl group to the IIB component gene gene1226 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06145 UM146_RS06150 UM146_05955 fruK fruK 1239994 1240932 + 1-phosphofructokinase converts fructose-1-phosphate and ATP to fructose-1%2C6-bisphosphate and ADP%3B highly specific for fructose-1-phopshate%3B similar to PfkB%3B forms homodimers gene gene1227 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06150 UM146_RS06155 UM146_05960 UM146_RS06155 1240949 1242640 + PTS fructose transporter subunit IIBC phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene1228 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06155 UM146_RS06160 UM146_05965 UM146_RS06160 1243096 1244037 + pseudouridine kinase gene gene1229 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06160 UM146_RS06165 UM146_05970 UM146_RS06165 1244138 1244962 + pseudouridine-5'-phosphate glycosidase gene gene1230 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06165 UM146_RS06170 UM146_05975 UM146_RS06170 1245056 1246306 + nucleoside permease gene gene1231 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06170 UM146_RS06175 UM146_05980 UM146_RS06175 1246373 1247071 - Crp/Fnr family transcriptional regulator activator of nucleoside metabolism gene gene1232 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06175 UM146_RS06180 UM146_05985 rihB rihB 1247201 1248142 + pyrimidine-specific ribonucleoside hydrolase RihB Hydrolyzes cytidine or uridine to ribose and cytosine or uracil%2C respectively gene gene1233 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06180 UM146_RS06185 UM146_05990 UM146_RS06185 1248410 1249498 - carbohydrate kinase gene gene1234 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06185 UM146_RS06190 UM146_05995 UM146_RS06190 1249502 1250359 - endonuclease Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues gene gene1235 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06190 UM146_RS06195 UM146_06000 UM146_RS06195 1250433 1251482 - hypothetical protein gene gene1236 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06195 UM146_RS06200 UM146_06005 UM146_RS06200 1251581 1252462 + transcriptional regulator gene gene1237 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06200 UM146_RS06205 UM146_06010 UM146_RS06205 1252667 1254136 + lysine transporter gene gene1238 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06205 UM146_RS06210 UM146_RS06210 UM146_RS06210 1254233 1254435 + hypothetical protein gene gene1239 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06210 UM146_RS06215 UM146_06015 UM146_RS06215 1254428 1256419 + catecholate siderophore receptor CirA Cir%3B FeuA%3B CirA%3B receptor protein for siderophores (colicin IA%2C IB and V) and microcins (E492%2C H47%2C and M)%3B TonB-dependent%3B able to transport monomers%2C dimer%2C and linear trimers of 2%2C3-dihydorxybenzoylserine%3B outer membrane protein gene gene1240 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06215 UM146_RS06220 UM146_06020 UM146_RS06220 1256451 1257287 - S-formylglutathione hydrolase YeiG gene gene1241 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06220 UM146_RS06225 UM146_RS06225 UM146_RS06225 1257215 1257391 - hypothetical protein gene gene1242 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06225 UM146_RS06230 UM146_06025 folE folE 1257545 1258213 + GTP cyclohydrolase 1 involved in the first step of tetrahydrofolate biosynthesis%3B catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1%2C2%2C3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water%3B forms a homopolymer gene gene1243 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06230 UM146_RS06235 UM146_06030 UM146_RS06235 1258230 1259387 + membrane protein gene gene1244 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06235 UM146_RS06240 UM146_RS06240 UM146_RS06240 1259336 1259539 - hypothetical protein gene gene1245 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06240 UM146_RS06245 UM146_06035 UM146_RS06245 1259529 1260569 + transcriptional regulator controls transcription of galETKM gene gene1246 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06245 UM146_RS06250 UM146_06040 UM146_RS06250 1260849 1261847 + D-galactose-binding periplasmic protein wtih MglAC is involved in the transport of beta-methylgalactoside gene gene1247 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06250 UM146_RS06255 UM146_06045 UM146_RS06255 1261908 1263428 + galactose/methyl galactoside import ATP-binding protein MglA gene gene1248 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06255 UM146_RS06260 UM146_06050 mglC mglC 1263444 1264454 + beta-methylgalactoside transporter ABC transporter%3B functions in galactose transport%3B part of MglA2C2B transporter complex gene gene1249 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06260 UM146_RS06265 UM146_06055 UM146_RS06265 1264697 1265932 - dihydropyrimidine dehydrogenase subunit B gene gene1250 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06265 UM146_RS06270 UM146_06060 UM146_RS06270 1265926 1267164 - dihydropyrimidine dehydrogenase subunit A gene gene1251 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06270 UM146_RS06275 UM146_06065 UM146_RS06275 1267358 1267597 - DUF2542 domain-containing protein gene gene1252 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06275 UM146_RS06280 UM146_06070 UM146_RS06280 1267600 1268319 - protein SanA involved in vancomycin sensitivity and other barrier functions of the cell envelope gene gene1253 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06280 UM146_RS06285 UM146_06075 UM146_RS06285 1268469 1269353 - cytidine deaminase Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis gene gene1254 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06285 UM146_RS06290 UM146_06080 UM146_RS06290 1269483 1270178 - hypothetical protein gene gene1255 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06290 UM146_RS06295 UM146_06085 UM146_RS06295 1270175 1270573 - hypothetical protein gene gene1256 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06295 UM146_RS06300 UM146_06090 UM146_RS06300 1270812 1271762 + tRNA-dihydrouridine synthase C gene gene1257 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06300 UM146_RS06305 UM146_RS06305 UM146_RS06305 1272150 1272233 - hypothetical protein gene gene1258 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06305 UM146_RS06310 UM146_06095 UM146_RS06310 1272457 1273893 + multidrug resistance outer membrane protein MdtQ may be involved in resistance to puromycin%2C acriflavine and tetraphenylarsonium chloride gene gene1259 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06310 UM146_RS06315 UM146_06100 UM146_RS06315 1273946 1274707 + oxidoreductase gene gene1260 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06315 UM146_RS06320 UM146_06105 UM146_RS06320 1274827 1275405 - membrane protein gene gene1261 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06320 UM146_RS06325 UM146_06110 UM146_RS06325 1275575 1276162 + hypothetical protein gene gene1262 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06325 UM146_RS06330 UM146_06115 pbpG pbpG 1276336 1277268 + D-alanyl-D-alanine endopeptidase specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi%3B Penicillin-binding protein 7 gene gene1263 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06330 UM146_RS06335 UM146_06120 UM146_RS06335 1277307 1279022 - lactate dehydrogenase component of the membrane-bound D-lactate oxidase%2C FAD-binding%2C NADH independent gene gene1264 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06335 UM146_RS06340 UM146_06125 UM146_RS06340 1279218 1281515 + beta-D-glucoside glucohydrolase catalyzes the hydrolysis of terminal beta-D-glucosyl residues gene gene1265 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06340 UM146_RS06345 UM146_06130 UM146_RS06345 1281705 1282622 + osmoprotectant uptake system substrate-binding protein gene gene1266 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06345 UM146_RS06350 UM146_06135 UM146_RS06350 1282629 1283786 + osmoprotectant uptake system permease gene gene1267 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06350 UM146_RS06355 UM146_06140 UM146_RS06355 1283779 1284705 + ATP-binding protein gene gene1268 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06355 UM146_RS06360 UM146_06145 UM146_RS06360 1284710 1285441 + osmoprotectant uptake system permease gene gene1269 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06360 UM146_RS06365 UM146_06150 UM146_RS06365 1285422 1285529 - membrane protein gene gene1270 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06365 UM146_RS06370 UM146_06155 UM146_RS06370 1285589 1286320 - MerR family transcriptional regulator gene gene1271 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06370 UM146_RS06375 UM146_06160 UM146_RS06375 1286542 1288227 + sensor histidine kinase gene gene1272 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06375 UM146_RS06380 UM146_06165 UM146_RS06380 1288224 1288943 + two-component system response regulator unknown function%3B when overproduced it confers drug-resistance gene gene1273 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06380 UM146_RS06385 UM146_06170 UM146_RS06385 1288990 1289460 + hypothetical protein gene gene1274 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06385 UM146_RS06390 UM146_06175 UM146_RS06390 1289501 1289962 - hypothetical protein gene gene1275 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06390 UM146_RS06395 UM146_RS06395 UM146_RS06395 1290087 1292089 - hypothetical protein gene gene1276 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06395 UM146_RS06400 UM146_06190 UM146_RS06400 1292086 1293222 - hypothetical protein gene gene1277 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06400 UM146_RS06405 UM146_06195 UM146_RS06405 1293215 1295491 - hypothetical protein gene gene1278 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06405 UM146_RS06410 UM146_06200 UM146_RS06410 1295498 1296586 - hypothetical protein gene gene1279 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06410 UM146_RS06415 UM146_RS06415 UM146_RS06415 1297016 1297105 + hypothetical protein gene gene1280 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06415 UM146_RS06420 UM146_RS06420 UM146_RS06420 1297365 1297681 - hypothetical protein gene gene1281 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06420 UM146_RS06425 UM146_RS06425 UM146_RS06425 1297742 1301373 - hypothetical protein gene gene1282 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06425 UM146_RS06430 UM146_06215 UM146_RS06430 1301383 1305171 - MolR family transcriptional regulator gene gene1283 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06430 UM146_RS06435 UM146_06220 metG metG 1305312 1307345 - methionine--tRNA ligase methionine--tRNA ligase%3B MetRS%3B adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate%3B some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not%3B four subfamilies exist based on sequence motifs and zinc content gene gene1284 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06435 UM146_RS06440 UM146_06225 UM146_RS06440 1307477 1308586 + protein mrp gene gene1285 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06440 UM146_RS06445 UM146_06230 UM146_RS06445 1308849 1309130 + hypothetical protein gene gene1286 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06445 UM146_RS06450 UM146_RS06450 UM146_RS06450 1309054 1309234 - hypothetical protein gene gene1287 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06450 UM146_RS06455 UM146_06235 UM146_RS06455 1309423 1309965 + hypothetical protein gene gene1288 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06455 UM146_RS06460 UM146_06240 UM146_RS06460 1310046 1310720 + fimbrial assembly chaperone protein StcB gene gene1289 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06460 UM146_RS06465 UM146_06245 UM146_RS06465 1310736 1313216 + fimbrial outer membrane usher protein gene gene1290 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06465 UM146_RS06470 UM146_06250 UM146_RS06470 1313232 1314266 + fimbrial protein gene gene1291 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06470 UM146_RS06475 UM146_06255 UM146_RS06475 1314347 1314685 - nickel/cobalt homeostasis protein RcnB gene gene1292 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06475 UM146_RS06480 UM146_06260 UM146_RS06480 1314904 1315728 - nickel/cobalt efflux system RcnA membrane protein conferring nickel and cobalt resistance gene gene1293 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06480 UM146_RS06485 UM146_06265 UM146_RS06485 1315849 1316121 + transcriptional regulator DNA-binding%3B binds the RcnA promotor gene gene1294 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06485 UM146_RS06490 UM146_06270 UM146_RS06490 1316344 1317132 + hydroxyethylthiazole kinase gene gene1295 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06490 UM146_RS06495 UM146_06275 UM146_RS06495 1317129 1317929 + bifunctional hydroxy-methylpyrimidine kinase/ hydroxy-phosphomethylpyrimidine kinase catalyzes the formation hydroxymethylpyrimidine phosphate from hydroxymethylpyrimidine and the formation of of 4-amino-2-methyl-5-diphosphomethylpyrimidine from hydroxymethylpyrimidine phosphate gene gene1296 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06495 UM146_RS06500 UM146_06280 UM146_RS06500 1317994 1318812 + hypothetical protein gene gene1297 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06500 UM146_RS06505 UM146_06285 UM146_RS06505 1318864 1319610 + GntR family transcriptional regulator gene gene1298 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06505 UM146_RS06510 UM146_06290 UM146_RS06510 1319584 1320549 - sugar kinase gene gene1299 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06510 UM146_RS06515 UM146_06295 UM146_RS06515 1320546 1321550 - hypothetical protein gene gene1300 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06515 UM146_RS06520 UM146_06300 UM146_RS06520 1321547 1322824 - nucleoside transporter gene gene1301 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06520 UM146_RS06525 UM146_06305 UM146_RS06525 1323081 1324133 + fructose-bisphosphate aldolase catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1%2C6-bisphosphate gene gene1302 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06525 UM146_RS06530 UM146_06310 gatY gatY 1324362 1325216 + tagatose-1%2C6-bisphosphate aldolase catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1%2C6-bisphosphate%3B in enteric bacteria there are two D-tagatose 1%2C6-bisphosphate-specific aldolases: KbaY (also called AgaY)%2C involved in catabolism of N-acetyl-galactosamine and D-galactosamine%2C and GatY which is part of the galactitol catabolism pathway gene gene1303 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06530 UM146_RS06535 UM146_06315 UM146_RS06535 1325245 1326507 + tagatose-1%2C6-bisphosphate aldolase part of the galacitol catabolism pathway%3B with GatY catalyzes the formation of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate from tagatose-1%2C6-bisphosphate gene gene1304 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06535 UM146_RS06540 UM146_06320 UM146_RS06540 1326517 1326969 + PTS galactitol transporter subunit IIA phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene1305 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06540 UM146_RS06545 UM146_06325 UM146_RS06545 1327000 1327284 + PTS galactitol transporter subunit IIB phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene1306 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06545 UM146_RS06550 UM146_06330 UM146_RS06550 1327288 1328643 + PTS galactitol transporter subunit IIC gene gene1307 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06550 UM146_RS06555 UM146_06335 UM146_RS06555 1328691 1329731 + galactitol-1-phosphate 5-dehydrogenase Zn-dependent%3B NAD(P)-binding%3B catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate gene gene1308 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06555 UM146_RS06560 UM146_06340 UM146_RS06560 1329837 1330610 + galactitol utilization operon repressor gene gene1309 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06560 UM146_RS06565 UM146_06345 UM146_RS06565 1330692 1331591 - lipid kinase cytosolic protein with phosphatidylglycerol kinase activity%3B undetermined physiological role gene gene1310 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06565 UM146_RS06570 UM146_06350 UM146_RS06570 1331992 1332324 + hypothetical protein gene gene1311 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06570 UM146_RS06580 UM146_06355 UM146_RS06580 1332824 1334185 - protease gene gene1312 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06580 UM146_RS06585 UM146_06360 UM146_RS06585 1334673 1335887 + hypothetical protein gene gene1313 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06585 UM146_RS06590 UM146_RS06590 UM146_RS06590 1335937 1336602 + hypothetical protein gene gene1314 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06590 UM146_RS06595 UM146_06375 UM146_RS06595 1336613 1338721 + membrane protein gene gene1315 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06595 UM146_RS06600 UM146_06380 UM146_RS06600 1338805 1339386 + hypothetical protein gene gene1316 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06600 UM146_RS06605 UM146_06385 UM146_RS06605 1339511 1339843 - hypothetical protein gene gene1317 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06605 UM146_RS06610 UM146_06390 UM146_RS06610 1340023 1340745 - two-component system response regulator response regulator in two-component regulatory system with BaeS%3B regulator of RNA synthesis%2C flagellar biosynthesis%2C chemotaxis and transport gene gene1318 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06610 UM146_RS06615 UM146_06395 UM146_RS06615 1340742 1342145 - two-component system sensor histidine kinase gene gene1319 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06615 UM146_RS06620 UM146_06400 UM146_RS06620 1342142 1343557 - transporter gene gene1320 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06620 UM146_RS06625 UM146_06405 UM146_RS06625 1343558 1346635 - multidrug resistance protein MdtC Part of a tripartite efflux system composed of MdtA%2C MdtB and MdtC which confers resistance against novobiocin and deoxycholate gene gene1321 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06625 UM146_RS06630 UM146_06410 UM146_RS06630 1346636 1349758 - multidrug resistance protein MdtB Part of a tripartite efflux system composed of MdtA%2C MdtB and MdtC which confers resistance against novobiocin and deoxycholate gene gene1322 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06630 UM146_RS06635 UM146_06415 UM146_RS06635 1349758 1351005 - multidrug transporter Part of a tripartite efflux system composed of MdtA%2C MdtB and MdtC which confers resistance against novobiocin and deoxycholate gene gene1323 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06635 UM146_RS06640 UM146_06420 UM146_RS06640 1351886 1352545 + hypothetical protein gene gene1324 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06640 UM146_RS06645 UM146_06425 UM146_RS06645 1352623 1353303 + hypothetical protein gene gene1325 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06645 UM146_RS06650 UM146_06430 UM146_RS06650 1353300 1355240 + hypothetical protein gene gene1326 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06650 UM146_RS06655 UM146_06435 UM146_RS06655 1355253 1356605 - chaperone gene gene1327 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06655 UM146_RS06660 UM146_06440 UM146_RS06660 1356739 1357587 + 3-methyl-adenine DNA glycosylase inducible%2C catalyzes the hydrolysis of alkylated DNA%2C releasing 3-methyladenine%2C 3-methylguanine%2C 7-methylguanine and 7-methyladenine gene gene1328 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06660 UM146_RS06665 UM146_06445 UM146_RS06665 1357698 1361015 - diguanylate cyclase gene gene1329 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06665 UM146_RS06670 UM146_06450 UM146_RS06670 1361333 1361974 + uridine kinase gene gene1330 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06670 UM146_RS06675 UM146_06455 UM146_RS06675 1362066 1362647 + deoxycytidine triphosphate deaminase gene gene1331 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06675 UM146_RS06680 UM146_06460 UM146_RS06680 1362669 1364522 + assembly protein YegA%3B inner membrane protein involved in the assembly of outer membrane proteins (OMPs)%3B asmA-null mutants show low lipopolysaccharide (LPS) levels%2C suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity%2C resulting on altered assembly of OMPs gene gene1332 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06680 UM146_RS06685 UM146_06465 UM146_RS06685 1364575 1364865 - XRE family transcriptional regulator gene gene1333 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06685 UM146_RS06690 UM146_06470 UM146_RS06690 1364855 1365193 - toxin RelE gene gene1334 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06690 UM146_RS06695 UM146_06475 UM146_RS06695 1365268 1366851 - membrane protein gene gene1335 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06695 UM146_RS06700 UM146_06480 UM146_RS06700 1367509 1368648 + lipoprotein required for the translocation of capsular polysaccharide through the outer membrane gene gene1336 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06700 UM146_RS06705 UM146_06485 UM146_RS06705 1368654 1369097 + protein-tyrosine phosphatase Wzb shows phosphatase activity towards the autophosphorylated Wzc protein%2C which induces colanic acid biosynthesis%3B catalyzes the phosphorylation of UDP-glucose dehydrogenase%2C an enzyme involved in colanic acid biosynthesis gene gene1337 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06705 UM146_RS06710 UM146_06490 UM146_RS06710 1369100 1371262 + tyrosine kinase Wzc%3B catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide) gene gene1338 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06710 UM146_RS06715 UM146_06495 UM146_RS06715 1371391 1372230 + glycosyl transferase gene gene1339 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06715 UM146_RS06720 UM146_06500 UM146_RS06720 1372233 1372721 + colanic acid biosynthesis acetyltransferase WcaB acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit)%3B wcaB is induced in sessile bacteria and by osmotic shock%2C and repressed when grown in rich medium gene gene1340 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06720 UM146_RS06725 UM146_06505 UM146_RS06725 1372718 1373935 + colanic acid biosynthesis glycosyltransferase WcaC gene gene1341 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06725 UM146_RS06730 UM146_06510 wcaD wcaD 1373910 1375130 + colanic acid biosynthesis protein essential for colanic acid biosynthesis%3B colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance gene gene1342 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06730 UM146_RS06735 UM146_06515 UM146_RS06735 1375211 1375957 + colanic acid biosynthesis glycosyltransferase WcaE gene gene1343 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06735 UM146_RS06740 UM146_06520 UM146_RS06740 1375973 1376521 + colanic acid biosynthesis acetyltransferase WcaF gene gene1344 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06740 UM146_RS06745 UM146_06525 UM146_RS06745 1376548 1377669 + GDP-mannose 4%2C6-dehydratase catalyzes the formation of GDP-4-dehydro-6-deoxy-D-mannose from GDP mannose gene gene1345 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06745 UM146_RS06750 UM146_06530 UM146_RS06750 1377672 1378637 + GDP-fucose synthetase bifunctional GDP-4-dehydro-6-deoxy-D-mannose epimerase/ GDP-4-dehydro-6-L-deoxygalactose reductase%3Bcatalyzes the formation of GDP-fucose from GDP-4-dehydro-6-deoxy-D-mannose gene gene1346 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06750 UM146_RS06755 UM146_06535 UM146_RS06755 1378640 1379119 + GDP-mannose mannosyl hydrolase catalyzes the formation of GDP and D-mannose from GDP-D-mannose%3B also hydrolyzes GDP-glucose gene gene1347 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06755 UM146_RS06760 UM146_RS06760 UM146_RS06760 1379116 1380338 + glycosyl transferase gene gene1348 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06760 UM146_RS06765 UM146_06550 cpsB cpsB 1380341 1381777 + mannose-1-phosphate guanylyltransferase 1 capsular polysaccharide colanic acid biosynthesis protein%3B catalyzes the formation of GDP-mannose from GTP and alpha-D-mannose 1-phosphate gene gene1349 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06765 UM146_RS06770 UM146_06555 UM146_RS06770 1381970 1383340 + phosphomannomutase capsular polysaccharide biosynthesis protein%3B catalyzes the formation of D-mannose 6-phosphate from alpha-D-mannose 1-phosphate gene gene1350 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06770 UM146_RS06775 UM146_06560 UM146_RS06775 1383394 1384788 + UDP-glucose lipid carrier transferase WcaJ%3B glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid gene gene1351 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06775 UM146_RS06780 UM146_06565 UM146_RS06780 1384790 1386268 + colanic acid exporter gene gene1352 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06780 UM146_RS06785 UM146_06570 UM146_RS06785 1386931 1388211 + colanic acid biosynthesis pyruvyl transferase WcaK gene gene1353 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06785 UM146_RS06790 UM146_06575 UM146_RS06790 1388208 1389428 + colanic acid biosynthesis glycosyltransferase WcaL gene gene1354 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06790 UM146_RS06795 UM146_06580 wcaM wcaM 1389439 1390833 + colanic acid biosynthesis protein WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface%3B may be involved in the biosynthesis of colanic acid gene gene1355 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06795 UM146_RS06800 UM146_06585 UM146_RS06800 1391008 1391901 + UTP--glucose-1-phosphate uridylyltransferase gene gene1356 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06800 UM146_RS06805 UM146_06590 UM146_RS06805 1392274 1393359 + dTDP-glucose 4%2C6-dehydratase gene gene1357 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06805 UM146_RS06810 UM146_06595 UM146_RS06810 1393359 1394258 + dTDP-4-dehydrorhamnose reductase with dTDP-4-dehydrorhamnose 3%2C5-epimerase forms a complex known as dTDP-L-rhamnose synthetase%3B catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose gene gene1358 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06810 UM146_RS06815 UM146_06600 UM146_RS06815 1394316 1395191 + glucose-1-phosphate thymidylyltransferase gene gene1359 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06815 UM146_RS06820 UM146_06605 UM146_RS06820 1395199 1395756 + dTDP-4-dehydrorhamnose 3%2C5-epimerase gene gene1360 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06820 UM146_RS06825 UM146_RS06825 UM146_RS06825 1395753 1396999 + polysaccharide biosynthesis protein gene gene1361 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06825 UM146_RS06830 UM146_RS06830 UM146_RS06830 1397056 1398245 + nucleoid-structuring protein H-NS gene gene1362 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06830 UM146_RS06835 UM146_RS06835 UM146_RS06835 1398227 1399161 + rhamnosyl transferase gene gene1363 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06835 UM146_RS06840 UM146_06635 UM146_RS06840 1399158 1399945 + glycosyl transferase family A gene gene1364 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06840 UM146_RS06845 UM146_06640 UM146_RS06845 1399942 1401048 + glycosyl transferase family 1 gene gene1365 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06845 UM146_RS06850 UM146_06645 UM146_RS06850 1401390 1402493 + glycosyl transferase family 1 gene gene1366 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06850 UM146_RS06855 UM146_06650 UM146_RS06855 1402634 1404040 + 6-phosphogluconate dehydrogenase catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate gene gene1367 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06855 UM146_RS06860 UM146_06655 UM146_RS06860 1404287 1405453 + UDP-glucose 6-dehydrogenase catalyzes the formation of UDP-glucuronate from UDP-glucose gene gene1368 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06860 UM146_RS06865 UM146_06660 UM146_RS06865 1405599 1406576 + chain-length determining protein regulator of length of O-antigen component of lipopolysaccharide chains gene gene1369 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06865 UM146_RS06870 UM146_06665 UM146_RS06870 1406762 1407373 - phosphoribosyl-AMP cyclohydrolase catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis gene gene1370 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06870 UM146_RS06875 UM146_06670 UM146_RS06875 1407367 1408143 - imidazole glycerol phosphate synthase subunit HisF gene gene1371 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06875 UM146_RS06880 UM146_06675 UM146_RS06880 1408125 1408862 - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase gene gene1372 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06880 UM146_RS06885 UM146_06680 hisH hisH 1408862 1409452 - imidazole glycerol phosphate synthase subunit HisH with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate%2C 5-aminoimidazol-4-carboxamide ribonucleotide%2C and glutamate in histidine biosynthesis%3B the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide gene gene1373 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06885 UM146_RS06890 UM146_06685 UM146_RS06890 1409452 1410519 - histidine biosynthesis bifunctional protein HisB catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate gene gene1374 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06890 UM146_RS06895 UM146_06690 UM146_RS06895 1410519 1411589 - histidinol-phosphate aminotransferase catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis gene gene1375 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06895 UM146_RS06900 UM146_06695 hisD hisD 1411586 1412890 - histidinol dehydrogenase catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis%3B functions as a dimer gene gene1376 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06900 UM146_RS06905 UM146_06700 hisG hisG 1412896 1413795 - ATP phosphoribosyltransferase long form of enzyme%3B catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate%3B crucial role in histidine biosynthesis%3B forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors gene gene1377 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06905 UM146_RS06910 UM146_06705 UM146_RS06910 1414274 1414525 + antitoxin YefM Antitoxin that counteracts the effect of the YoeB toxin gene gene1378 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06910 UM146_RS06915 UM146_06710 UM146_RS06915 1414522 1414776 + toxin YoeB gene gene1379 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06915 UM146_RS06920 UM146_06715 UM146_RS06920 1414859 1415683 + hypothetical protein gene gene1380 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06920 UM146_RS06925 UM146_06720 UM146_RS06925 1415729 1416658 + LysR family transcriptional regulator gene gene1381 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06925 UM146_RS06930 UM146_06725 UM146_RS06930 1416925 1418283 + amino acid transporter gene gene1382 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06930 UM146_RS06935 UM146_06730 sbcB sbcB 1418357 1419781 - exonuclease I Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates gene gene1383 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06935 UM146_RS06940 UM146_06740 UM146_RS06940 1419993 1421158 + D-alanyl-D-alanine carboxypeptidase removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors%3B penicillin-binding protein 6B%3B one of four%2C DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains gene gene1384 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06940 UM146_RS06945 UM146_06745 UM146_RS06945 1421277 1421750 + DNA gyrase inhibitor gene gene1385 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06945 UM146_RS06950 UM146_06750 UM146_RS06950 1421948 1423006 + membrane protein gene gene1386 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06950 UM146_RS06955 UM146_06755 UM146_RS06955 1423178 1423507 + hypothetical protein gene gene1387 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06955 UM146_RS06960 UM146_RS06960 UM146_RS06960 1423608 1423790 - hypothetical protein gene gene1388 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06960 UM146_RS06965 UM146_RS06965 UM146_RS06965 1424279 1424392 - hypothetical protein gene gene1389 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06965 UM146_RS06970 UM146_06765 UM146_RS06970 1424405 1424599 - hypothetical protein gene gene1390 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06970 UM146_RS06975 UM146_06770 UM146_RS06975 1424596 1424970 - toxin CbtA gene gene1391 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06975 UM146_RS06980 UM146_06775 UM146_RS06980 1425059 1425427 - antitoxin gene gene1392 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06980 UM146_RS06985 UM146_06780 UM146_RS06985 1425501 1425722 - hypothetical protein gene gene1393 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06985 UM146_RS06990 UM146_06785 UM146_RS06990 1425791 1426267 - hypothetical protein gene gene1394 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06990 UM146_RS06995 UM146_06790 UM146_RS06995 1426282 1426755 - hypothetical protein gene gene1395 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS06995 UM146_RS07000 UM146_06795 UM146_RS07000 1427018 1427839 - hypothetical protein gene gene1396 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07000 UM146_RS07005 UM146_06800 UM146_RS07005 1428060 1428470 - hypothetical protein gene gene1397 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07005 UM146_RS07010 UM146_06805 UM146_RS07010 1428486 1429163 - hypothetical protein gene gene1398 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07010 UM146_RS07015 UM146_06810 UM146_RS07015 1429299 1430369 - phospholipase gene gene1399 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07015 UM146_RS07020 UM146_06815 UM146_RS07020 1430366 1431271 - chemotaxis protein gene gene1400 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07020 UM146_RS07025 UM146_06820 UM146_RS07025 1431268 1433652 - hypothetical protein gene gene1401 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07025 UM146_RS07035 UM146_06830 UM146_RS07035 1434733 1436898 + fatty-acid--CoA ligase gene gene1403 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07035 UM146_RS07040 UM146_06835 UM146_RS07040 1436909 1437898 + ABC transporter substrate-binding protein gene gene1404 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07040 UM146_RS07045 UM146_06840 UM146_RS07045 1437917 1438975 + iron-siderophore ABC transporter permease gene gene1405 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07045 UM146_RS07050 UM146_06845 UM146_RS07050 1438972 1439739 + iron ABC transporter gene gene1406 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07050 UM146_RS07055 UM146_06850 UM146_RS07055 1439793 1440050 + hypothetical protein gene gene1407 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07055 UM146_RS07060 UM146_06855 UM146_RS07060 1440581 1441753 - hypothetical protein gene gene1408 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07060 UM146_RS07065 UM146_RS07065 UM146_RS07065 1442925 1443161 - transposase gene gene1409 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07065 UM146_RS07070 UM146_06865 UM146_RS07070 1443250 1444272 + transposase gene gene1410 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07070 UM146_RS07075 UM146_06870 UM146_RS07075 1444272 1445051 + transposase gene gene1411 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07075 UM146_RS07080 UM146_RS07080 UM146_RS07080 1445061 1445273 - transposase gene gene1412 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07080 UM146_RS07085 UM146_06880 UM146_RS07085 1446077 1446679 - hypothetical protein gene gene1413 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07085 UM146_RS07090 UM146_06885 UM146_RS07090 1446773 1446979 - Rha family transcriptional regulator gene gene1414 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07090 UM146_RS07095 UM146_06890 UM146_RS07095 1447175 1448371 - transposase gene gene1415 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07095 UM146_RS07100 UM146_06895 UM146_RS07100 1448576 1448836 + hypothetical protein gene gene1416 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07100 UM146_RS07105 UM146_06900 UM146_RS07105 1449171 1449311 + hypothetical protein gene gene1417 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07105 UM146_RS07110 UM146_06905 UM146_RS07110 1449551 1449751 - hypothetical protein gene gene1418 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07110 UM146_RS07115 UM146_06910 UM146_RS07115 1449951 1450520 + hypothetical protein gene gene1419 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07115 UM146_RS07120 UM146_06915 UM146_RS07120 1450686 1451087 + hypothetical protein gene gene1420 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07120 UM146_RS07125 UM146_06920 UM146_RS07125 1451075 1451485 + hypothetical protein gene gene1421 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07125 UM146_RS07130 UM146_RS07130 UM146_RS07130 1451908 1452123 - hypothetical protein gene gene1422 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07130 UM146_RS07135 UM146_RS07135 UM146_RS07135 1452291 1453148 + transposase gene gene1423 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07135 UM146_RS07140 UM146_06935 UM146_RS07140 1453227 1453388 + hypothetical protein gene gene1424 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07140 UM146_RS07145 UM146_06945 UM146_RS07145 1453647 1453760 + gamma-glutamyltranspeptidase gene gene1425 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07145 UM146_RS07150 UM146_06950 UM146_RS07150 1453800 1454834 - phosphotriesterase gene gene1426 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07150 UM146_RS07155 UM146_06955 UM146_RS07155 1454837 1455721 - membrane protein gene gene1427 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07155 UM146_RS07160 UM146_06960 UM146_RS07160 1455856 1456614 - hypothetical protein gene gene1428 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07160 UM146_RS07165 UM146_RS07165 UM146_RS07165 1456628 1457841 - ribokinase gene gene1429 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07165 UM146_RS07170 UM146_06975 UM146_RS07170 1458037 1458153 - transposase gene gene1430 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07170 UM146_RS07175 UM146_06980 UM146_RS07175 1458217 1459350 + transposase gene gene1431 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07175 UM146_RS07180 UM146_06985 UM146_RS07180 1459579 1459776 - hypothetical protein gene gene1432 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07180 UM146_RS07185 UM146_06990 UM146_RS07185 1460290 1461063 - membrane protein gene gene1433 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07185 UM146_RS07190 UM146_06995 UM146_RS07190 1461065 1461505 - transferase gene gene1434 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07190 UM146_RS07195 UM146_07000 UM146_RS07195 1461624 1462820 - membrane protein gene gene1435 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07195 UM146_RS07200 UM146_07005 UM146_RS07200 1462834 1463496 - GlcNAc-PI de-N-acetylase gene gene1436 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07200 UM146_RS07205 UM146_07010 UM146_RS07205 1464535 1465758 + hypothetical protein gene gene1437 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07205 UM146_RS07210 UM146_07015 UM146_RS07210 1465743 1466387 + transcriptional regulator gene gene1438 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07210 UM146_RS07215 UM146_07025 UM146_RS07215 1466758 1468905 - ligand-gated channel gene gene1439 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07215 UM146_RS07220 UM146_07030 UM146_RS07220 1469948 1470112 + hypothetical protein gene gene1440 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07220 UM146_RS07230 UM146_07035 cobU cobU 1470577 1471122 + adenosylcobinamide kinase catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP gene gene1441 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07230 UM146_RS07235 UM146_07040 cobS cobS 1471119 1471862 + adenosylcobinamide-GDP ribazoletransferase catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole gene gene1442 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07235 UM146_RS07240 UM146_07045 cobT cobT 1471874 1472953 + nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5%2C6-dimethylbenzimidazole gene gene1443 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07240 UM146_RS07245 UM146_07050 UM146_RS07245 1473018 1473950 + transpeptidase catalyzes th removal of D-alanine and attachment of the murein lipoprotein to the peptidoglycan tetrapeptide chain gene gene1444 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07245 UM146_RS07250 UM146_07055 UM146_RS07250 1474269 1474667 + hypothetical protein gene gene1445 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07250 UM146_RS07255 UM146_07065 UM146_RS07255 1474975 1475454 - transposase gene gene1446 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07255 UM146_RS07265 UM146_RS07265 UM146_RS07265 1475971 1476704 - 4'-phosphopantetheinyl transferase gene gene1448 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07265 UM146_RS07270 UM146_07090 UM146_RS07270 1476705 1476917 - LuxR family transcriptional regulator gene gene1449 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07270 UM146_RS07275 UM146_07095 UM146_RS07275 1477319 1486939 + non-ribosomal peptide synthetase gene gene1450 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07275 UM146_RS07280 UM146_07100 UM146_RS07280 1486980 1489580 + polyketide synthase gene gene1451 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07280 UM146_RS07285 UM146_RS07285 UM146_RS07285 1489590 1490458 + 3-hydroxybutyryl-CoA dehydrogenase gene gene1452 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07285 UM146_RS07290 UM146_07115 UM146_RS07290 1490488 1490736 + D-alanine--poly(phosphoribitol) ligase gene gene1453 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07290 UM146_RS07295 UM146_07120 UM146_RS07295 1490740 1491870 + acyl-CoA dehydrogenase gene gene1454 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07295 UM146_RS07300 UM146_07125 UM146_RS07300 1491867 1493135 + transacylase gene gene1455 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07300 UM146_RS07305 UM146_07130 UM146_RS07305 1493183 1497979 + non-ribosomal peptide synthetase gene gene1456 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07305 UM146_RS07310 UM146_07135 UM146_RS07310 1498029 1501061 + polyketide synthase gene gene1457 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07310 UM146_RS07315 UM146_07140 UM146_RS07315 1501105 1507603 + peptide synthetase gene gene1458 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07315 UM146_RS07320 UM146_07145 UM146_RS07320 1507614 1514078 + non-ribosomal peptide synthetase gene gene1459 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07320 UM146_RS07325 UM146_07150 UM146_RS07325 1514071 1515534 + amidase gene gene1460 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07325 UM146_RS07330 UM146_07155 UM146_RS07330 1515596 1517035 + MATE family efflux transporter gene gene1461 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07330 UM146_RS07335 UM146_07160 UM146_RS07335 1517032 1521399 + non-ribosomal peptide synthetase gene gene1462 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07335 UM146_RS07340 UM146_07165 UM146_RS07340 1521430 1523889 + polyketide synthase gene gene1463 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07340 UM146_RS07345 UM146_RS07345 UM146_RS07345 1523911 1525415 + beta-lactamase gene gene1464 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07345 UM146_RS07350 UM146_RS07350 UM146_RS07350 1525561 1526130 + thioesterase gene gene1465 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07350 UM146_RS07355 UM146_07185 UM146_RS07355 1526165 1526677 + hypothetical protein gene gene1466 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07355 UM146_RS07360 UM146_RS07360 UM146_RS07360 1526662 1526955 + hypothetical protein gene gene1467 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07360 UM146_RS07365 UM146_07190 UM146_RS07365 1526957 1528228 - integrase gene gene1468 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07365 UM146_RS07370 UM146_t23861 UM146_RS07370 1528390 1528465 - tRNA-Asn tRNA gene1469 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07370 UM146_RS07375 UM146_07195 UM146_RS07375 1528566 1528790 - multidrug transporter MATE gene gene1470 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07375 UM146_RS07380 UM146_07200 UM146_RS07380 1528840 1529094 - hypothetical protein gene gene1471 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07380 UM146_RS07385 UM146_t23863 UM146_RS07385 1529291 1529366 - tRNA-Asn tRNA gene1472 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07385 UM146_RS07390 UM146_07205 UM146_RS07390 1529693 1530610 + LysR family transcriptional regulator Transcriptional activator for the hut%2C put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation gene gene1473 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07390 UM146_RS07395 UM146_07210 cbl cbl 1530712 1531662 + CysB family transcriptional regulator LysR-type transcriptional regulator similar to CysB%3B contains helix-turn-helix (HTH) motif%3B in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon%3B regulated by CysB%3B DNA-binding transcriptional activator for the ssuEADCB and tauABCD operons gene gene1474 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07395 UM146_RS07400 UM146_t23865 UM146_RS07400 1531700 1531775 - tRNA-Asn tRNA gene1475 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07400 UM146_RS07405 UM146_07215 UM146_RS07405 1531969 1533420 + MATE efflux family protein gene gene1476 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07405 UM146_RS07410 UM146_t23867 UM146_RS07410 1533521 1533596 + tRNA-Asn tRNA gene1477 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07410 UM146_RS07415 UM146_07220 UM146_RS07415 1534048 1534764 - transcriptional regulator gene gene1478 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07415 UM146_RS07420 UM146_07225 UM146_RS07420 1535107 1536561 - AMP nucleosidase Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile gene gene1479 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07420 UM146_RS07425 UM146_07230 UM146_RS07425 1536663 1537979 - shikimate transporter gene gene1480 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07425 UM146_RS07430 UM146_07235 UM146_RS07430 1538294 1539345 + hypothetical protein gene gene1481 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07430 UM146_RS07435 UM146_RS07435 UM146_RS07435 1539473 1539922 - invasin gene gene1482 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07435 UM146_RS07440 UM146_RS07440 UM146_RS07440 1539962 1541431 - hypothetical protein gene gene1483 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07440 UM146_RS07445 UM146_07250 UM146_RS07445 1541467 1541607 - adhesin gene gene1484 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07445 UM146_RS07450 UM146_07255 UM146_RS07450 1541564 1542313 - hypothetical protein gene gene1485 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07450 UM146_RS07455 UM146_07260 UM146_RS07455 1542964 1544985 - ligand-gated channel protein gene gene1486 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07455 UM146_RS07460 UM146_07265 UM146_RS07460 1545117 1546694 - salicyl-AMP ligase gene gene1487 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07460 UM146_RS07465 UM146_07270 UM146_RS07465 1546698 1547501 - thioesterase gene gene1488 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07465 UM146_RS07470 UM146_07275 UM146_RS07470 1547498 1548598 - oxidoreductase gene gene1489 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07470 UM146_RS07475 UM146_07280 UM146_RS07475 1548595 1558086 - polyketide synthase gene gene1490 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07475 UM146_RS07480 UM146_07285 UM146_RS07480 1558174 1563621 - non-ribosomal peptide synthetase gene gene1491 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07480 UM146_RS07485 UM146_07290 UM146_RS07485 1563845 1564288 - yersiniabactin biosynthetic protein gene gene1492 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07485 UM146_RS07490 UM146_07295 UM146_RS07490 1564479 1565438 - AraC family transcriptional regulator gene gene1493 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07490 UM146_RS07495 UM146_07300 UM146_RS07495 1565695 1567407 + ABC transporter ATP-binding protein gene gene1494 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07495 UM146_RS07500 UM146_07305 UM146_RS07500 1567394 1569196 + ABC transporter permease gene gene1495 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07500 UM146_RS07505 UM146_07310 UM146_RS07505 1569189 1570469 + MFS transporter gene gene1496 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07505 UM146_RS07510 UM146_07315 UM146_RS07510 1570497 1571801 + salicylate synthase catalyzes the conversion of chorismate to salicylate in the biosynthesis of the siderophore yersiniabactin gene gene1497 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07510 UM146_RS07515 UM146_RS07515 UM146_RS07515 1571995 1573257 - integrase gene gene1498 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07515 UM146_RS07520 UM146_t23869 UM146_RS07520 1573419 1573494 - tRNA-Asn tRNA gene1499 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07520 UM146_RS07525 UM146_07330 UM146_RS07525 1573595 1574392 - protein MtfA Mlc anti-repressor%3B regulates ptsG by binding and inactivating Mlc gene gene1500 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07525 UM146_RS07530 UM146_t23871 UM146_RS07530 1574486 1574575 + tRNA-Ser tRNA gene1501 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07530 UM146_RS07535 UM146_RS07535 UM146_RS07535 1574880 1575209 - hypothetical protein gene gene1502 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07535 UM146_RS07540 UM146_07335 UM146_RS07540 1575245 1575895 - zinc/cadmium-binding protein gene gene1503 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07540 UM146_RS07545 UM146_07340 UM146_RS07545 1576152 1576787 - sulfoxide reductase heme-binding subunit YedZ in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY%3B sulfite oxidase activity not demonstrated%3B contains heme gene gene1504 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07545 UM146_RS07550 UM146_07345 UM146_RS07550 1576788 1577792 - sulfoxide reductase catalytic subunit YedY in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase%3B requires inner membrane anchor protein YedZ gene gene1505 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07550 UM146_RS07555 UM146_07350 UM146_RS07555 1577901 1578314 - 5-hydroxyisourate hydrolase catalyzes the formation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline from 5-hydroxyisourate gene gene1506 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07555 UM146_RS07560 UM146_07355 UM146_RS07560 1578447 1579118 + two-component system response regulator induced by CusR in the presence of copper%3B YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW%3B yedVW is one of four copper regulons found in E. coli%3B part of the copper homeostasis mechanism%3B confers resistance to copper and several drugs when induced gene gene1507 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07560 UM146_RS07565 UM146_07360 UM146_RS07565 1579118 1580476 + two-component system sensor histidine kinase gene gene1508 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07565 UM146_RS07570 UM146_07365 UM146_RS07570 1580583 1581434 - Molecular chaperone Hsp31 and glyoxalase 3 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress gene gene1509 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07570 UM146_RS07575 UM146_RS07575 UM146_RS07575 1581595 1581949 - hypothetical protein gene gene1510 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07575 UM146_RS07580 UM146_07370 UM146_RS07580 1582030 1583145 - outer membrane protein F gene gene1511 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07580 UM146_RS07585 UM146_RS07585 UM146_RS07585 1583364 1583618 - hypothetical protein gene gene1512 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07585 UM146_RS07590 UM146_07375 UM146_RS07590 1583774 1584076 + permease gene gene1513 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07590 UM146_RS07595 UM146_07380 UM146_RS07595 1584116 1584811 + hydrolase gene gene1514 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07595 UM146_RS07600 UM146_07385 UM146_RS07600 1584878 1586296 + DNA-cytosine methyltransferase gene gene1515 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07600 UM146_RS07605 UM146_07390 UM146_RS07605 1586277 1586747 + very short patch repair endonuclease DNA mismatch endonuclease%3B recognizes and repairs T:G mismatches gene gene1516 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07605 UM146_RS07610 UM146_07395 UM146_RS07610 1586736 1587656 - amino acid exporter for phenylalanine%2C threonine gene gene1517 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07610 UM146_RS07615 UM146_07400 UM146_RS07615 1587829 1588746 + membrane protein gene gene1518 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07615 UM146_RS07620 UM146_07410 UM146_RS07620 1589196 1590872 + diguanylate cyclase catalyzes the formation of cyclic di-3'%2C5'-guanylate from guanosine triphosphate%3B involved in the regulation of cellulose biosynthesis gene gene1519 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07620 UM146_RS07625 UM146_07415 UM146_RS07625 1590869 1591684 - mannosyl-3-phosphoglycerate phosphatase catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate gene gene1520 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07625 UM146_RS07630 UM146_07420 UM146_RS07630 1591982 1592209 - hypothetical protein gene gene1521 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07630 UM146_RS07635 UM146_07425 UM146_RS07635 1592372 1592560 + protein DsrB gene gene1522 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07635 UM146_RS07640 UM146_07430 rcsA rcsA 1592604 1593227 - transcriptional regulator with RcsB is a positive regulator of capsular polysaccharide synthesis genes gene gene1523 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07640 UM146_RS07645 UM146_07435 fliR fliR 1593517 1594302 - flagellar biosynthesis protein FliR FliR%2C with proteins FliP and FliQ%2C forms the core of the central channel in the flagella export apparatus gene gene1524 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07645 UM146_RS07650 UM146_07440 fliQ fliQ 1594311 1594580 - flagellar biosynthetic protein FliQ with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus gene gene1525 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07650 UM146_RS07655 UM146_07445 fliP fliP 1594590 1595327 - flagellar biosynthesis protein FliP FliP%2C with proteins FliQ and FliR%2C forms the core of the central channel in the flagella export apparatus gene gene1526 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07655 UM146_RS07660 UM146_07450 UM146_RS07660 1595327 1595692 - flagellar protein FliO with FlhA%2C FlhB%2C FliP%2C FliQ and FliR is one of the membrane components of the flagellar export apparatus gene gene1527 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07660 UM146_RS07665 UM146_07455 fliN fliN 1595695 1596108 - flagellar motor switch protein FliN One of three proteins involved in switching the direction of the flagellar rotation gene gene1528 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07665 UM146_RS07670 UM146_07460 fliM fliM 1596105 1597109 - flagellar motor switch protein FliM with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation gene gene1529 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07670 UM146_RS07675 UM146_07465 fliL fliL 1597114 1597578 - flagellar protein FliL interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring gene gene1530 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07675 UM146_RS07680 UM146_07470 UM146_RS07680 1597683 1598810 - flagellar hook-length control protein FliK gene gene1531 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07680 UM146_RS07685 UM146_07475 fliJ fliJ 1598807 1599250 - flagellar biosynthesis chaperone rod/hook and filament chaperone gene gene1532 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07685 UM146_RS07690 UM146_07480 fliI fliI 1599269 1600642 - ATP synthase involved in type III protein export during flagellum assembly gene gene1533 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07690 UM146_RS07695 UM146_07485 fliH fliH 1600642 1601328 - flagellar assembly protein H binds to and inhibits the function of flagella specific ATPase FliI gene gene1534 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07695 UM146_RS07700 UM146_07490 fliG fliG 1601321 1602316 - flagellar motor switch protein FliG One of three proteins involved in switching the direction of the flagellar rotation gene gene1535 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07700 UM146_RS07705 UM146_07495 fliF fliF 1602309 1603967 - flagellar MS-ring protein the MS-ring anchors the flagellum to the cytoplasmic membrane%3B part of the flagellar basal body which consists of four rings L%2C P%2C S%2C and M mounted on a central rod gene gene1536 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07705 UM146_RS07710 UM146_07500 fliE fliE 1604182 1604496 + flagellar hook-basal body complex protein FliE forms a junction between the M-ring and FlgB during flagella biosynthesis gene gene1537 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07710 UM146_RS07715 UM146_RS07715 UM146_RS07715 1604416 1604741 - integrase gene gene1538 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07715 UM146_RS07725 UM146_07505 UM146_RS07725 1604841 1605173 + multidrug SMR transporter gene gene1539 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07725 UM146_RS07730 UM146_07510 UM146_RS07730 1605341 1605892 + kinase inhibitor gene gene1540 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07730 UM146_RS07735 UM146_07515 UM146_RS07735 1605902 1606699 + transcriptional regulator gene gene1541 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07735 UM146_RS07740 UM146_07520 UM146_RS07740 1607201 1608283 - porin gene gene1542 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07740 UM146_RS07745 UM146_07525 UM146_RS07745 1608795 1609463 - hypothetical protein gene gene1543 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07745 UM146_RS07750 UM146_07530 UM146_RS07750 1609572 1609805 - TusA family sulfurtransferase gene gene1544 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07750 UM146_RS07755 UM146_07535 UM146_RS07755 1609802 1611007 - hypothetical protein gene gene1545 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07755 UM146_RS07760 UM146_07540 UM146_RS07760 1611194 1611607 + lipoprotein gene gene1546 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07760 UM146_RS07765 UM146_07545 UM146_RS07765 1611641 1613128 - alpha-amylase converts 1%2C4-alpha-D-glucans to maltodextrin gene gene1547 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07765 UM146_RS07770 UM146_07550 UM146_RS07770 1613206 1613571 - flagellar protein FliT binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway%3B acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription%3B member of the type III cytoplasmic chaperone family gene gene1548 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07770 UM146_RS07775 UM146_07555 fliS fliS 1613571 1613981 - flagellar export chaperone FliS flagellin specific chaperone gene gene1549 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07775 UM146_RS07780 UM146_07560 fliD fliD 1614006 1615412 - flagellar capping protein involved in flagellin assembly gene gene1550 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07780 UM146_RS07785 UM146_07565 UM146_RS07785 1615677 1617434 + flagellin gene gene1551 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07785 UM146_RS07790 UM146_07570 fliA fliA 1617754 1618473 + RNA polymerase sigma factor FliA sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B this sigma factor directs late flagellar biosynthesis genes gene gene1552 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07790 UM146_RS07795 UM146_07575 UM146_RS07795 1618519 1619070 + flagellar biosynthesis protein FliZ expression activator of the class 2 type of flagellar operons%2C essential to achieve maximal cell motility%3B activator of type 1 fimbrial gene expression%3B cell density-responsive regulator%3B FliZ in Salmonella typhimurium induces HilA%2C an activator of invasion genes necessary to achieve full virulence gene gene1553 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07795 UM146_RS07800 UM146_07580 UM146_RS07800 1619158 1619958 + cystine-binding periplasmic protein gene gene1554 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07800 UM146_RS07805 UM146_07585 UM146_RS07805 1620063 1621049 + D-cysteine desulfhydrase catalyzes the formation of pyruvate from D-cysteine gene gene1555 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07805 UM146_RS07810 UM146_07590 UM146_RS07810 1621064 1621732 + amino acid ABC transporter permease gene gene1556 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07810 UM146_RS07815 UM146_07595 UM146_RS07815 1621729 1622481 + amino acid ABC transporter ATP-binding protein gene gene1557 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07815 UM146_RS07820 UM146_07600 UM146_RS07820 1622711 1623433 + transcriptional regulator regulates genes involved in cell division gene gene1558 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07820 UM146_RS07825 UM146_07605 UM146_RS07825 1623501 1623725 - hypothetical protein gene gene1559 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07825 UM146_RS07830 UM146_RS07830 UM146_RS07830 1623712 1623888 - 2-oxo acid dehydrogenase gene gene1560 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07830 UM146_RS07835 UM146_07610 sirA sirA 1624184 1624840 + transcriptional regulator in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system%3B in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system gene gene1561 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07835 UM146_RS07840 UM146_07615 uvrC uvrC 1624837 1626669 + UvrABC system protein C The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision gene gene1562 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07840 UM146_RS07845 UM146_07620 UM146_RS07845 1626726 1627274 + CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase gene gene1563 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07845 UM146_RS07850 UM146_t23873 UM146_RS07850 1627426 1627501 + tRNA-Gly tRNA gene1564 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07850 UM146_RS07855 UM146_t23875 UM146_RS07855 1627555 1627628 + tRNA-Cys tRNA gene1565 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07855 UM146_RS07860 UM146_t23877 UM146_RS07860 1627641 1627727 + tRNA-Leu tRNA gene1566 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07860 UM146_RS07865 UM146_07625 UM146_RS07865 1627923 1628588 + hypothetical protein gene gene1567 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07865 UM146_RS07870 UM146_RS07870 UM146_RS07870 1628639 1629849 - tyrosine transporter TyrP tyrosine specific permease gene gene1568 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07870 UM146_RS07875 UM146_07640 UM146_RS07875 1630040 1630279 + hypothetical protein gene gene1569 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07875 UM146_RS07880 UM146_07645 UM146_RS07880 1630317 1630814 - non-heme ferritin cytoplasmic iron storage protein gene gene1570 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07880 UM146_RS07885 UM146_RS07885 UM146_RS07885 1630986 1631309 - hypothetical protein gene gene1571 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07885 UM146_RS07890 UM146_RS07890 UM146_RS07890 1631516 1631662 - hypothetical protein gene gene1572 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07890 UM146_RS07895 UM146_07655 UM146_RS07895 1631774 1632025 + hypothetical protein gene gene1573 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07895 UM146_RS07900 UM146_07660 UM146_RS07900 1632103 1632606 - non-heme ferritin ferritin B%3B required for virulence in Salmonella%3B may be involved in repair of damaged Fe-S clusters gene gene1574 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07900 UM146_RS07905 UM146_07665 UM146_RS07905 1633403 1634392 + arabinose ABC transporter substrate-binding protein with AraGH is involved in the transport of arabinose into the cell gene gene1575 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07905 UM146_RS07910 UM146_07670 araG araG 1634462 1635976 + arabinose import ATP-binding protein AraG Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose gene gene1576 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07910 UM146_RS07915 UM146_07675 araH araH 1635991 1636977 + arabinose ABC transporter permease Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose gene gene1577 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07915 UM146_RS07920 UM146_RS07920 UM146_RS07920 1637144 1637943 + trehalose phosphatase biosynthetic%3B catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate%3B expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature gene gene1578 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07920 UM146_RS07925 UM146_07680 UM146_RS07925 1637918 1639342 + alpha%2Calpha-trehalose-phosphate synthase [UDP-forming] gene gene1579 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07925 UM146_RS07930 UM146_07685 UM146_RS07930 1639349 1639777 - universal stress protein C ppGpp-dependent%3B membrane-associated%2C stress protein produced under conditions of nutrient deprivation%2C osmotic shock and oxidative stress gene gene1580 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07930 UM146_RS07935 UM146_07690 UM146_RS07935 1640557 1640907 + flagellar transcriptional regulator FlhD with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems gene gene1581 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07935 UM146_RS07940 UM146_07695 UM146_RS07940 1640910 1641488 + flagellar transcriptional regulator FlhC With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems gene gene1582 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07940 UM146_RS07945 UM146_07700 UM146_RS07945 1641615 1642502 + flagellar motor protein MotA With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine gene gene1583 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07945 UM146_RS07950 UM146_07705 motB motB 1642499 1643425 + flagellar motor protein MotB with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine gene gene1584 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07950 UM146_RS07955 UM146_07710 UM146_RS07955 1643436 1645394 + chemotaxis protein CheA gene gene1585 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07955 UM146_RS07960 UM146_07715 UM146_RS07960 1645415 1645918 + chemotaxis protein CheW gene gene1586 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07960 UM146_RS07965 UM146_07720 UM146_RS07965 1646063 1647724 + methyl-accepting chemotaxis protein serine sensor receptor gene gene1587 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07965 UM146_RS07975 UM146_07730 UM146_RS07975 1648015 1648875 + chemotaxis protein CheR methylates the MCP gene gene1588 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07975 UM146_RS07980 UM146_07735 UM146_RS07980 1648878 1649927 + two-component system protein-glutamate methylesterase response regulator regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins gene gene1589 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07980 UM146_RS07985 UM146_07740 UM146_RS07985 1649942 1650331 + chemotaxis protein CheY chemotaxis regulator that%2C when phosphorylated%2C interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble gene gene1590 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07985 UM146_RS07990 UM146_07745 UM146_RS07990 1650342 1650986 + protein phosphatase CheZ cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation gene gene1591 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07990 UM146_RS07995 UM146_07755 flhB flhB 1651195 1652343 + flagellar biosynthetic protein FlhB membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export gene gene1592 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS07995 UM146_RS08000 UM146_07760 UM146_RS08000 1652336 1654414 + flagellar biosynthesis protein FlhA gene gene1593 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08000 UM146_RS08005 UM146_07765 UM146_RS08005 1654414 1654806 + flagellar protein flhE gene gene1594 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08005 UM146_RS08010 UM146_07770 UM146_RS08010 1654859 1656592 - arginine--tRNA ligase gene gene1595 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08010 UM146_RS08015 UM146_07780 UM146_RS08015 1656808 1657374 + hypothetical protein gene gene1596 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08015 UM146_RS08020 UM146_07785 UM146_RS08020 1657388 1658133 + copper homeostasis protein CutC gene gene1597 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08020 UM146_RS08025 UM146_07790 UM146_RS08025 1658521 1659621 + cytochrome C gene gene1598 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08025 UM146_RS08030 UM146_07795 UM146_RS08030 1659646 1662075 + trimethylamine N-oxide reductase I catalytic subunit catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine gene gene1599 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08030 UM146_RS08035 UM146_07800 UM146_RS08035 1662240 1663211 - tRNA (mo5U34)-methyltransferase catalyzes the conversion of 5-hydroxyuridine to 5-methoxyuridine in tRNA gene gene1600 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08035 UM146_RS08040 UM146_07805 UM146_RS08040 1663208 1663951 - tRNA (cmo5U34)-methyltransferase catalyzes the conversion of 5-methoxyuridine to uridine-5-oxyacetic acid in tRNA gene gene1601 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08040 UM146_RS08045 UM146_RS08045 UM146_RS08045 1663992 1664387 - hypothetical protein gene gene1602 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08045 UM146_RS08050 UM146_RS08050 UM146_RS08050 1664440 1665257 - hypothetical protein gene gene1603 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08050 UM146_RS08055 UM146_07815 UM146_RS08055 1665254 1665820 - hydrolase gene gene1604 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08055 UM146_RS08060 UM146_07820 UM146_RS08060 1666130 1667902 + aspartate--tRNA ligase gene gene1605 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08060 UM146_RS08065 UM146_07825 nudB nudB 1667904 1668347 + dATP pyrophosphohydrolase catalyzes the formation of dihydroneopterin phosphate from dihydroneopterin triphosphate gene gene1606 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08065 UM146_RS08070 UM146_07830 UM146_RS08070 1668376 1669116 + transcriptional regulator gene gene1607 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08070 UM146_RS08075 UM146_07835 ruvC ruvC 1669151 1669672 + crossover junction endodeoxyribonuclease RuvC endonuclease%3B resolves Holliday structures%3B forms a complex of RuvABC%3B the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration%3B RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity gene gene1608 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08075 UM146_RS08080 UM146_07840 UM146_RS08080 1669674 1670276 - hypothetical protein gene gene1609 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08080 UM146_RS08085 UM146_07845 ruvA ruvA 1670552 1671163 + Holliday junction DNA helicase RuvA plays an essential role in ATP-dependent branch migration of the Holliday junction gene gene1610 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08085 UM146_RS08090 UM146_07850 UM146_RS08090 1671172 1672182 + Holliday junction DNA helicase RuvB gene gene1611 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08090 UM146_RS08095 UM146_07855 znuB znuB 1672399 1673184 - zinc transporter involved in transport of zinc(II) with ZnuA and C gene gene1612 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08095 UM146_RS08100 UM146_07860 znuC znuC 1673181 1673936 - Mn2+/Zn2+ABC transporter ATP-binding protein involved in transport of zinc(II) with ZnuA and C gene gene1613 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08100 UM146_RS08105 UM146_07865 znuA znuA 1674015 1674947 + zinc ABC transporter substrate-binding protein involved in transport of zinc(II) with ZnuA and C gene gene1614 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08105 UM146_RS08110 UM146_07870 UM146_RS08110 1674963 1676285 + murein DD-endopeptidase MepM gene gene1615 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08110 UM146_RS08115 UM146_07875 UM146_RS08115 1676379 1677374 + lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase Transfers myristate or laurate%2C activated on ACP%2C to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA gene gene1616 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08115 UM146_RS08120 UM146_07880 UM146_RS08120 1677506 1678948 - pyruvate kinase catalyzes the formation of phosphoenolpyruvate from pyruvate gene gene1617 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08120 UM146_RS08125 UM146_07885 UM146_RS08125 1679076 1679945 - transcriptional regulator Represses the expression of the zwf%2C eda%2C glp and gap gene gene1618 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08125 UM146_RS08130 UM146_07890 UM146_RS08130 1679968 1680117 + hypothetical protein gene gene1619 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08130 UM146_RS08135 UM146_07895 UM146_RS08135 1680283 1681758 + glucose-6-phosphate 1-dehydrogenase catalyzes the formation of D-glucono-1%2C5-lactone 6-phosphate from D-glucose 6-phosphate gene gene1620 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08135 UM146_RS08140 UM146_07900 UM146_RS08140 1681993 1683804 + phosphogluconate dehydratase catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate gene gene1621 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08140 UM146_RS08145 UM146_07905 UM146_RS08145 1683841 1684482 + KHG/KDPG aldolase catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate%3B or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate gene gene1622 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08145 UM146_RS08150 UM146_07910 UM146_RS08150 1684538 1685716 - phosphoribosylglycinamide formyltransferase 2 gene gene1623 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08150 UM146_RS08155 UM146_07915 UM146_RS08155 1685850 1686140 + DNA damage-inducible protein gene gene1624 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08155 UM146_RS08160 UM146_07920 UM146_RS08160 1686207 1686563 + hypothetical protein secreted protein%3B unknown function gene gene1625 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08160 UM146_RS08165 UM146_07925 UM146_RS08165 1686720 1686830 - hypothetical protein gene gene1626 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08165 UM146_RS08170 UM146_07930 UM146_RS08170 1686890 1687549 + hypothetical protein gene gene1627 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08170 UM146_RS08175 UM146_07935 UM146_RS08175 1687758 1689818 + protease PtrB%3B oligopeptidase that cleaves peptide bonds following arginine and lysine residues gene gene1628 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08175 UM146_RS08180 UM146_07940 UM146_RS08180 1689815 1690477 - exodeoxyribonuclease 10 3'-5' exonuclease activity on single or double-strand DNA gene gene1629 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08180 UM146_RS08185 UM146_07945 UM146_RS08185 1690500 1691156 - hypothetical protein gene gene1630 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08185 UM146_RS08190 UM146_07950 UM146_RS08190 1691258 1691488 - DNA polymerase III subunit theta gene gene1631 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08190 UM146_RS08195 UM146_07955 UM146_RS08195 1691627 1692001 + hypothetical protein gene gene1632 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08195 UM146_RS08200 UM146_07960 UM146_RS08200 1692005 1692877 + membrane protein gene gene1633 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08200 UM146_RS08205 UM146_07965 UM146_RS08205 1692893 1693231 + hypothetical protein gene gene1634 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08205 UM146_RS08210 UM146_07970 UM146_RS08210 1693249 1693401 + hypothetical protein gene gene1635 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08210 UM146_RS08215 UM146_07975 UM146_RS08215 1693626 1694282 + serine/threonine protein phosphatase gene gene1636 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08215 UM146_RS08220 UM146_RS08220 UM146_RS08220 1694283 1694474 - hypothetical protein gene gene1637 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08220 UM146_RS08225 UM146_07985 UM146_RS08225 1694579 1694815 - hypothetical protein gene gene1638 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08225 UM146_RS08230 UM146_07990 yebU yebU 1694933 1696372 - ribosomal RNA small subunit methyltransferase F in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA gene gene1639 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08230 UM146_RS08235 UM146_07995 UM146_RS08235 1696452 1699085 - hypothetical protein gene gene1640 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08235 UM146_RS08240 UM146_08000 UM146_RS08240 1699054 1700337 - hypothetical protein gene gene1641 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08240 UM146_RS08245 UM146_08005 UM146_RS08245 1700467 1700964 + hypothetical protein gene gene1642 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08245 UM146_RS08250 UM146_08010 UM146_RS08250 1701061 1701759 + RNA chaperone ProQ affects solute and DNA transport through an unknown mechanism gene gene1643 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08250 UM146_RS08255 UM146_08015 UM146_RS08255 1701814 1703826 + carboxyl-terminal processing protease Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 gene gene1644 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08255 UM146_RS08260 UM146_08020 UM146_RS08260 1704018 1704899 + protease HtpX metalloprotease gene gene1645 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08260 UM146_RS08265 UM146_08025 UM146_RS08265 1704944 1706317 - multidrug MFS transporter gene gene1646 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08265 UM146_RS08270 UM146_08030 UM146_RS08270 1706494 1707285 + transcriptional regulator regulates the genes involved in 2-keto-3-deoxy gluconate transport and catabolism gene gene1647 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08270 UM146_RS08275 UM146_08035 UM146_RS08275 1707429 1707668 - hypothetical protein gene gene1648 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08275 UM146_RS08280 UM146_08040 UM146_RS08280 1707827 1707970 + PhoP family transcriptional regulator gene gene1649 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08280 UM146_RS08285 UM146_08045 UM146_RS08285 1708045 1708332 + hypothetical protein gene gene1650 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08285 UM146_RS08290 UM146_RS08290 UM146_RS08290 1708836 1709041 - hypothetical protein gene gene1651 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08290 UM146_RS08295 UM146_08050 UM146_RS08295 1709003 1709146 + DUF2527 domain-containing protein gene gene1652 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08295 UM146_RS08300 UM146_08055 UM146_RS08300 1709159 1709368 + cold-shock protein CspC gene gene1653 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08300 UM146_RS08305 UM146_08060 rrmA rrmA 1709534 1710343 + 23S rRNA methyltransferase methylates the guanosine in position 745 of 23S rRNA%3B required for translation and cell growth gene gene1654 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08305 UM146_RS08310 UM146_08065 UM146_RS08310 1710340 1710906 - manganese efflux pump MntP membrane protein YebN gene gene1655 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08310 UM146_RS08315 UM146_RS08315 UM146_RS08315 1710903 1711148 - hypothetical protein gene gene1656 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08315 UM146_RS08320 UM146_08070 UM146_RS08320 1711335 1711793 - membrane protein gene gene1657 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08320 UM146_RS08325 UM146_08075 UM146_RS08325 1711848 1712699 - mannose permease IID component hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IID with IIC forms the translocation channel gene gene1658 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08325 UM146_RS08330 UM146_08080 UM146_RS08330 1712712 1713512 - mannose permease IIC component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site gene gene1659 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08330 UM146_RS08335 UM146_08085 UM146_RS08335 1713575 1714546 - PTS mannose EIIAB component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B subunit IIA transfers a phosphoryl group to subunit IIB%3B subunit IIB transfers the phosphoryl group to the substrate gene gene1660 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08335 UM146_RS08340 UM146_RS08340 UM146_RS08340 1714812 1715021 + hypothetical protein gene gene1661 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08340 UM146_RS08345 UM146_08090 UM146_RS08345 1715009 1716565 + hypothetical protein gene gene1662 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08345 UM146_RS08350 UM146_08095 UM146_RS08350 1716569 1718167 - cyclic di-GMP phosphodiesterase gene gene1663 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08350 UM146_RS08355 UM146_08100 UM146_RS08355 1718298 1719662 - L-serine dehydratase 1 catalyzes the formation of pyruvate from serine gene gene1664 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08355 UM146_RS08360 UM146_08105 UM146_RS08360 1719846 1720424 - NUDIX hydrolase gene gene1665 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08360 UM146_RS08365 UM146_08110 pabB pabB 1720428 1721789 - aminodeoxychorismate synthase subunit I para-aminobenzoate synthase component 1%3B catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and L-glutamine gene gene1666 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08365 UM146_RS08370 UM146_08115 UM146_RS08370 1721863 1722042 + hypothetical protein gene gene1667 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08370 UM146_RS08375 UM146_08120 UM146_RS08375 1722162 1722461 - hypothetical protein gene gene1668 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08375 UM146_RS08380 UM146_RS08380 UM146_RS08380 1722718 1722807 + hypothetical protein gene gene1669 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08380 UM146_RS08385 UM146_08125 UM146_RS08385 1722883 1723227 - hypothetical protein gene gene1670 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08385 UM146_RS08390 UM146_08130 UM146_RS08390 1723359 1725269 + ATP-dependent helicase gene gene1671 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08390 UM146_RS08395 UM146_08135 UM146_RS08395 1725327 1726022 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaB gene gene1672 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08395 UM146_RS08400 UM146_08140 UM146_RS08400 1726062 1726643 + Slp family lipoprotein%2C RpoE-regulated gene gene1673 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08400 UM146_RS08405 UM146_08145 UM146_RS08405 1726815 1728533 + long-chain fatty acid--CoA ligase Activates fatty acids by binding to coenzyme A gene gene1674 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08405 UM146_RS08410 UM146_08150 UM146_RS08410 1728615 1729730 + ribonuclease D gene gene1675 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08410 UM146_RS08415 UM146_RS08415 UM146_RS08415 1729820 1729990 - dehydrogenase gene gene1676 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08415 UM146_RS08420 UM146_RS08420 UM146_RS08420 1729979 1730146 + LysR family transcriptional regulator gene gene1677 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08420 UM146_RS08425 UM146_08155 UM146_RS08425 1730273 1730911 + leucine efflux protein gene gene1678 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08425 UM146_RS08430 UM146_08160 UM146_RS08430 1731084 1731443 + hypothetical protein gene gene1679 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08430 UM146_RS08435 UM146_08165 UM146_RS08435 1731447 1731629 + hypothetical protein gene gene1680 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08435 UM146_RS08440 UM146_08170 UM146_RS08440 1731777 1732025 + membrane protein gene gene1681 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08440 UM146_RS08445 UM146_RS08445 UM146_RS08445 1732161 1732259 - hypothetical protein gene gene1682 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08445 UM146_RS08450 UM146_08175 UM146_RS08450 1732292 1733317 - diguanylate cyclase gene gene1683 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08450 UM146_RS08455 UM146_08180 UM146_RS08455 1733500 1733754 + DUF333 domain-containing protein gene gene1684 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08455 UM146_RS08460 UM146_08185 UM146_RS08460 1733776 1734123 - hypothetical protein gene gene1685 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08460 UM146_RS08465 UM146_08190 UM146_RS08465 1734178 1735359 - membrane protein gene gene1686 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08465 UM146_RS08470 UM146_08195 UM146_RS08470 1735456 1736277 + AraC family transcriptional regulator gene gene1687 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08470 UM146_RS08475 UM146_08200 UM146_RS08475 1736234 1736680 - membrane protein gene gene1688 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08475 UM146_RS08480 UM146_RS08480 UM146_RS08480 1736802 1736954 + hypothetical protein gene gene1689 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08480 UM146_RS08485 UM146_08210 UM146_RS08485 1736955 1737458 - hypothetical protein gene gene1690 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08485 UM146_RS08490 UM146_08215 UM146_RS08490 1737501 1738991 - diguanylate cylase gene gene1691 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08490 UM146_RS08495 UM146_08220 UM146_RS08495 1739172 1740506 - membrane protein gene gene1692 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08495 UM146_RS08500 UM146_08225 UM146_RS08500 1740794 1742077 - hypothetical protein gene gene1693 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08500 UM146_RS08505 UM146_08230 UM146_RS08505 1742190 1744124 - protein kinase endogenous substrate unidentified%3B autokinase gene gene1694 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08505 UM146_RS08510 UM146_08235 UM146_RS08510 1744560 1745306 + MltA-interacting protein scaffolding protein for the murein polymerase MrcB and the lytic transglycosylase MltA gene gene1695 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08510 UM146_RS08515 UM146_08240 UM146_RS08515 1745396 1746250 + hypothetical protein gene gene1696 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08515 UM146_RS08520 UM146_08245 UM146_RS08520 1746301 1747185 - glucose-6-phosphate 1-epimerase gene gene1697 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08520 UM146_RS08525 UM146_08250 UM146_RS08525 1747269 1748264 - glyceraldehyde-3-phosphate dehydrogenase gene gene1698 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08525 UM146_RS08530 UM146_08255 UM146_RS08530 1748606 1749018 + methionine sulfoxide reductase B gene gene1699 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08530 UM146_RS08535 UM146_08260 UM146_RS08535 1749060 1749332 + hypothetical protein gene gene1700 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08535 UM146_RS08540 UM146_08265 UM146_RS08540 1749702 1750778 + alcohol dehydrogenase gene gene1701 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08540 UM146_RS08545 UM146_08270 UM146_RS08545 1750805 1752184 + transporter gene gene1702 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08545 UM146_RS08550 UM146_08275 UM146_RS08550 1752201 1753244 + alcohol dehydrogenase gene gene1703 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08550 UM146_RS08555 UM146_08280 UM146_RS08555 1753265 1754101 + hypothetical protein gene gene1704 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08555 UM146_RS08560 UM146_08285 UM146_RS08560 1754106 1755053 + sugar kinase gene gene1705 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08560 UM146_RS08565 UM146_08290 UM146_RS08565 1755063 1756043 + oxidoreductase gene gene1706 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08565 UM146_RS08570 UM146_08295 UM146_RS08570 1756180 1756938 + DeoR family transcriptional regulator gene gene1707 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08570 UM146_RS08575 UM146_08300 UM146_RS08575 1757056 1758414 + MFS transporter gene gene1708 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08575 UM146_RS08580 UM146_08305 UM146_RS08580 1758507 1759148 - nicotinamidase/pyrazinamidase catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide gene gene1709 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08580 UM146_RS08585 UM146_08310 ansA ansA 1759159 1760175 - asparaginase converts asparagine to aspartate and ammonia gene gene1710 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08585 UM146_RS08590 UM146_08315 UM146_RS08590 1760342 1762198 - signal peptide peptidase SppA SppA%3B catalyzes the degradation of cleaved signal peptides%3B essential to maintain secretion of mature proteins across the membrane gene gene1711 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08590 UM146_RS08595 UM146_RS08595 UM146_RS08595 1762141 1762305 - hypothetical protein gene gene1712 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08595 UM146_RS08600 UM146_08320 UM146_RS08600 1762359 1762910 + oxidoreductase gene gene1713 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08600 UM146_RS08605 UM146_RS08605 UM146_RS08605 1762936 1763085 + hypothetical protein gene gene1714 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08605 UM146_RS08610 UM146_08325 UM146_RS08610 1763027 1764070 + selenophosphate synthase catalyzes the formation of selenophosphate from selenide and ATP gene gene1715 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08610 UM146_RS08615 UM146_08330 UM146_RS08615 1764075 1766030 + DNA topoisomerase III decatenates replicating daughter chromosomes gene gene1716 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08615 UM146_RS08620 UM146_08335 UM146_RS08620 1766107 1767450 - glutamate dehydrogenase converts 2-oxoglutarate to glutamate%3B in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction%3B uses NADPH%3B forms a homohexamer gene gene1717 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08620 UM146_RS08625 UM146_08340 UM146_RS08625 1767686 1767958 + hypothetical protein gene gene1718 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08625 UM146_RS08630 UM146_08345 UM146_RS08630 1767924 1768331 - pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase gene gene1719 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08630 UM146_RS08635 UM146_08350 UM146_RS08635 1768418 1769038 + membrane protein gene gene1720 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08635 UM146_RS08640 UM146_08355 UM146_RS08640 1769047 1770354 - thiosulfate sulfurtransferase gene gene1721 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08640 UM146_RS08645 UM146_08360 UM146_RS08645 1770421 1771074 - sulfate ABC transporter ATP-binding protein gene gene1722 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08645 UM146_RS08650 UM146_08365 UM146_RS08650 1771074 1772609 - thiamine ABC transporter permease gene gene1723 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08650 UM146_RS08655 UM146_RS08655 UM146_RS08655 1772582 1773747 - hypothetical protein gene gene1724 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08655 UM146_RS08660 UM146_08380 UM146_RS08660 1773757 1774305 - hypothetical protein gene gene1725 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08660 UM146_RS08665 UM146_08385 UM146_RS08665 1774305 1775012 - hypothetical protein gene gene1726 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08665 UM146_RS08670 UM146_08390 UM146_RS08670 1775026 1775703 - hypothetical protein gene gene1727 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08670 UM146_RS08675 UM146_08395 UM146_RS08675 1775708 1776418 - membrane protein gene gene1728 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08675 UM146_RS08680 UM146_08400 UM146_RS08680 1776585 1777391 - exonuclease III gene gene1729 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08680 UM146_RS08685 UM146_08405 UM146_RS08685 1777837 1779057 + succinylornithine aminotransferase catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate%3B also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate gene gene1730 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08685 UM146_RS08690 UM146_08410 UM146_RS08690 1779054 1780088 + arginine N-succinyltransferase gene gene1731 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08690 UM146_RS08695 UM146_08415 astD astD 1780085 1781563 + N-succinylglutamate 5-semialdehyde dehydrogenase a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity%3B converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH gene gene1732 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08695 UM146_RS08700 UM146_08425 UM146_RS08700 1781560 1782903 + N-succinylarginine dihydrolase catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine%2C ammonia and carbon dioxide in arginine degradation gene gene1733 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08700 UM146_RS08705 UM146_08430 UM146_RS08705 1782896 1783864 + succinylglutamate desuccinylase catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism gene gene1734 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08705 UM146_RS08710 UM146_08435 UM146_RS08710 1784193 1784678 + hypothetical protein periplasmic protein induced by stress response via Cpx and BaeSR system%3B similar to CpxP gene gene1735 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08710 UM146_RS08715 UM146_08440 UM146_RS08715 1784881 1785456 + protein Ves gene gene1736 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08715 UM146_RS08720 UM146_08445 UM146_RS08720 1785416 1786303 - excinuclease cho 3' incision activity%3B acts with UvrC gene gene1737 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08720 UM146_RS08725 UM146_RS08725 UM146_RS08725 1786373 1786564 + hypothetical protein gene gene1738 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08725 UM146_RS08730 UM146_08450 nadE nadE 1786533 1787360 - nH(3)-dependent NAD+ synthetase catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP%3B ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one%3B forms homodimers gene gene1739 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08730 UM146_RS08735 UM146_08455 UM146_RS08735 1787562 1787900 + transcriptional regulator osmotically-inducible lipoprotein E%3B activator of ntr-like gene protein gene gene1740 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08735 UM146_RS08740 UM146_08460 UM146_RS08740 1788199 1788519 + N%2CN'-diacetylchitobiose-specific phosphotransferase enzyme IIB component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B involved in N%2CN'-diacetylchitobiose transport%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene1741 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08740 UM146_RS08745 UM146_08465 UM146_RS08745 1788604 1789962 + PTS N'-diacetylchitobiose transporter subunit IIC catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B involved in N%2CN'-diacetylchitobiose transport%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene1742 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08745 UM146_RS08750 UM146_08470 UM146_RS08750 1790013 1790363 + N%2CN'-diacetylchitobiose-specific phosphotransferase enzyme IIA component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B involved N%2CN'-diacetylchitobiose transport%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene1743 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08750 UM146_RS08755 UM146_08475 UM146_RS08755 1790374 1791213 + transcriptional regulator represses the celABCDF-ydjC operon involved in carbon uptake gene gene1744 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08755 UM146_RS08760 UM146_08480 UM146_RS08760 1791317 1792669 + diacetylchitobiose-6-phosphate hydrolase catalyzes the fromation of N-acetyl-D-glucosamine and N-acetyl-D-glucosamine-6-phosphate from diacetylchitobiose-6-phosphate gene gene1745 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08760 UM146_RS08765 UM146_08485 UM146_RS08765 1792682 1793440 + chitooligosaccharide deacetylase gene gene1746 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08765 UM146_RS08770 UM146_08490 katE katE 1793486 1795747 - hydroperoxidase II Catalase HPII%3B monofunctional catalase that decomposes hydrogen peroxide into water and oxygen%3B serves to protect cells from the toxic effects of hydrogen peroxide gene gene1747 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08770 UM146_RS08775 UM146_08495 UM146_RS08775 1795951 1796193 + cell division activator CedA gene gene1748 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08775 UM146_RS08780 UM146_08500 UM146_RS08780 1796240 1797631 - L-cystine transporter tcyP gene gene1749 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08780 UM146_RS08785 UM146_08505 UM146_RS08785 1797764 1798354 - membrane protein gene gene1750 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08785 UM146_RS08790 UM146_08510 UM146_RS08790 1798518 1799186 - 2-deoxyglucose-6-phosphate phosphatase YniC%3B catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate%2C mannose 6-phosphate and p-nitrophenyl phosphate gene gene1751 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08790 UM146_RS08795 UM146_08515 UM146_RS08795 1799333 1799869 + membrane protein gene gene1752 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08795 UM146_RS08800 UM146_08520 UM146_RS08800 1799910 1800770 - hypothetical protein gene gene1753 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08800 UM146_RS08805 UM146_08525 UM146_RS08805 1800876 1801166 - hypothetical protein gene gene1754 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08805 UM146_RS08810 UM146_08530 UM146_RS08810 1801267 1802196 - ATP-dependent 6-phosphofructokinase gene gene1755 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08810 UM146_RS08815 UM146_08535 UM146_RS08815 1802482 1803240 + membrane protein gene gene1756 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08815 UM146_RS08820 UM146_08540 UM146_RS08820 1803293 1803400 - hypothetical protein gene gene1757 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08820 UM146_RS08825 UM146_RS08825 UM146_RS08825 1803807 1804601 - hypothetical protein gene gene1758 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08825 UM146_RS08830 UM146_08555 thrS thrS 1805123 1807051 + threonine--tRNA ligase catalyzes a two-step reaction%2C first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) gene gene1759 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08830 UM146_RS08835 UM146_RS08835 UM146_RS08835 1807055 1807597 + translation initiation factor IF-3 gene gene1760 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08835 UM146_RS08840 UM146_08565 UM146_RS08840 1807694 1807891 + 50S ribosomal protein L35 gene gene1761 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08840 UM146_RS08845 UM146_08570 rplT rplT 1807944 1808300 + 50S ribosomal protein L20 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit gene gene1762 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08845 UM146_RS08850 UM146_08575 UM146_RS08850 1808542 1808637 + hypothetical protein gene gene1763 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08850 UM146_RS08855 UM146_08580 UM146_RS08855 1808751 1809734 + phenylalanine--tRNA ligase subunit alpha gene gene1764 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08855 UM146_RS08860 UM146_08585 pheT pheT 1809749 1812136 + phenylalanine--tRNA ligase subunit beta catalyzes a two-step reaction%2C first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B forms a tetramer of alpha(2)beta(2)%3B binds two magnesium ions per tetramer%3B type 2 subfamily gene gene1765 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08860 UM146_RS08865 UM146_08590 ihfA ihfA 1812141 1812440 + integration host factor subunit alpha This protein is one of the two subunits of integration host factor%2C a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control gene gene1766 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08865 UM146_RS08870 UM146_08595 UM146_RS08870 1812541 1813521 + vitamin B12 import system permease BtuC with BtuD and BtuF transports vitamin B12 into the cell gene gene1767 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08870 UM146_RS08875 UM146_08600 btuE btuE 1813583 1814134 + glutathione peroxidase similar to glutathione peroxidase%3B member of the btuCED operon which is required for vitamin B12 transport across the inner membrane gene gene1768 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08875 UM146_RS08880 UM146_08605 UM146_RS08880 1814134 1814883 + vitamin B12 import ATP-binding protein BtuD ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell gene gene1769 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08880 UM146_RS08885 UM146_08610 UM146_RS08885 1814961 1815425 + endopeptidase gene gene1770 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08885 UM146_RS08890 UM146_08615 UM146_RS08890 1815672 1816385 + cyclic di-GMP regulator CdgR gene gene1771 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08890 UM146_RS08895 UM146_08620 UM146_RS08895 1816448 1817884 + hypothetical protein gene gene1772 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08895 UM146_RS08900 UM146_08625 UM146_RS08900 1817888 1818079 - hypothetical protein gene gene1773 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08900 UM146_RS08905 UM146_08630 UM146_RS08905 1818211 1819257 - phospho-2-dehydro-3-deoxyheptonate aldolase Trp-sensitive gene gene1774 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08905 UM146_RS08910 UM146_08635 UM146_RS08910 1819414 1820247 - phosphoenolpyruvate synthase regulatory protein gene gene1775 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08910 UM146_RS08915 UM146_RS08915 UM146_RS08915 1820359 1820526 + hypothetical protein gene gene1776 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08915 UM146_RS08920 UM146_08640 UM146_RS08920 1820580 1822958 + phosphoenolpyruvate synthase catalyzes the formation of phosphoenolpyruvate from pyruvate gene gene1777 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08920 UM146_RS08925 UM146_08645 UM146_RS08925 1823015 1824661 - short chain acyl-CoA synthetase acts in anaerobic beta-oxidation of fatty acids%3B possible ligase/synthase involved in anaerobic growth on fatty acids gene gene1778 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08925 UM146_RS08930 UM146_08650 UM146_RS08930 1824718 1825011 - ferredoxin ydiT gene gene1779 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08930 UM146_RS08935 UM146_08655 UM146_RS08935 1825008 1826297 - oxidoreductase FixC FAD/NAD(P)-binding domain%3B possibly part of an electron transfer system required for anaerobic carnitine reduction gene gene1780 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08935 UM146_RS08940 UM146_08660 fixB fixB 1826352 1827290 - electron transfer flavoprotein subunit alpha involved in electron transfer during carnitine metabolism gene gene1781 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08940 UM146_RS08945 UM146_08665 UM146_RS08945 1827310 1828074 - electron transfer flavoprotein FixB gene gene1782 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08945 UM146_RS08950 UM146_RS08950 UM146_RS08950 1828111 1828287 + hypothetical protein gene gene1783 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08950 UM146_RS08955 UM146_08670 UM146_RS08955 1828390 1829301 + AraC family transcriptional regulator gene gene1784 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08955 UM146_RS08960 UM146_08675 UM146_RS08960 1829344 1830495 - acyl-CoA dehydrogenase may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain gene gene1785 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08960 UM146_RS08965 UM146_08680 UM146_RS08965 1830509 1832104 - hypothetical protein gene gene1786 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08965 UM146_RS08970 UM146_08685 UM146_RS08970 1832250 1833008 - 3-dehydroquinate dehydratase gene gene1787 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08970 UM146_RS08975 UM146_08690 UM146_RS08975 1833039 1833905 - quinate/shikimate dehydrogenase YdiB%3B quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate gene gene1788 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08975 UM146_RS08980 UM146_08695 UM146_RS08980 1833917 1835182 - transporter gene gene1789 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08980 UM146_RS08985 UM146_08700 UM146_RS08985 1835409 1836623 - transporter gene gene1790 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08985 UM146_RS08990 UM146_08705 UM146_RS08990 1836723 1837079 - hypothetical protein gene gene1791 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08990 UM146_RS08995 UM146_RS08995 UM146_RS08995 1837508 1838621 - hypothetical protein YdiK%3B inner membrane protein%3B ydiK promoter presents a PurR sequence%2C suggesting that its expression is purine-regulated%3B unknown function gene gene1792 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS08995 UM146_RS09000 UM146_08720 UM146_RS09000 1838835 1841891 + membrane protein gene gene1793 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09000 UM146_RS09005 UM146_08725 UM146_RS09005 1841888 1842298 + acyl-CoA esterase required for efficient enterobactin production gene gene1794 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09005 UM146_RS09010 UM146_RS09010 UM146_RS09010 1842398 1842586 + hypothetical protein gene gene1795 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09010 UM146_RS09015 UM146_08735 sufA sufA 1843135 1843503 + protein SufA functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]%3B [4Fe-4S]) are assembled%3B forms a homodimer%3B similar to IscA protein gene gene1796 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09015 UM146_RS09020 UM146_08740 UM146_RS09020 1843512 1844999 + cysteine desulfurase activator complex subunit SufB with SufCD activates cysteine desulfurase SufS gene gene1797 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09020 UM146_RS09025 UM146_08745 sufC sufC 1845009 1845755 + Fe-S cluster assembly ATPase SufC part of SUF system involved in inserting iron-sulfur clusters into proteins%3B in Escherichia coli this protein forms a complex with SufBD%3B the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE gene gene1798 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09025 UM146_RS09030 UM146_08750 UM146_RS09030 1845730 1847001 + Fe-S cluster assembly protein SufD with SufBC activates cysteine desulfurase SufS gene gene1799 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09030 UM146_RS09035 UM146_08755 UM146_RS09035 1846998 1848218 + cysteine desulfurase gene gene1800 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09035 UM146_RS09040 UM146_08760 UM146_RS09040 1848231 1848647 + cysteine desulfuration protein SufE Acts with SufS to catalyze the formation of L-alanine from L-cysteine gene gene1801 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09040 UM146_RS09045 UM146_08765 UM146_RS09045 1848796 1849800 + murein transpeptidase catalyzes the formation of a meso-diaminopimelyl-3-a meso-diaminopimelyl-3 cross-link in peptidoglycan synthesis gene gene1802 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09045 UM146_RS09050 UM146_08770 UM146_RS09050 1849863 1850099 - murein lipoprotein major outer membrane lipoprotein%3B interacts with peptidoglycan to maintain the integrity of the cell envelope gene gene1803 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09050 UM146_RS09055 UM146_08775 UM146_RS09055 1850408 1851820 - pyruvate kinase I catalyzes the formation of phosphoenolpyruvate from pyruvate gene gene1804 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09055 UM146_RS09060 UM146_08780 UM146_RS09060 1852377 1852586 + hypothetical protein gene gene1805 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09060 UM146_RS09065 UM146_08785 UM146_RS09065 1853042 1853668 + hypothetical protein gene gene1806 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09065 UM146_RS09070 UM146_08790 UM146_RS09070 1853689 1855791 + oxidoreductase gene gene1807 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09070 UM146_RS09075 UM146_08795 UM146_RS09075 1855804 1856442 + hypothetical protein gene gene1808 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09075 UM146_RS09080 UM146_RS09080 UM146_RS09080 1856506 1857174 + ferredoxin gene gene1809 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09080 UM146_RS09085 UM146_08805 UM146_RS09085 1857171 1857956 + thiosulfate reductase cytochrome B gene gene1810 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09085 UM146_RS09090 UM146_08810 UM146_RS09090 1857960 1858772 + hypothetical protein gene gene1811 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09090 UM146_RS09095 UM146_08815 UM146_RS09095 1858784 1860388 - hypothetical protein gene gene1812 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09095 UM146_RS09100 UM146_08820 UM146_RS09100 1860514 1860819 - monooxygenase gene gene1813 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09100 UM146_RS09105 UM146_t23879 UM146_RS09105 1860927 1861003 - tRNA-Val tRNA gene1814 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09105 UM146_RS09110 UM146_t23881 UM146_RS09110 1861008 1861084 - tRNA-Val tRNA gene1815 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09110 UM146_RS09115 UM146_08825 UM146_RS09115 1861393 1862649 + hypothetical protein gene gene1816 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09115 UM146_RS09120 UM146_08830 UM146_RS09120 1862690 1864063 - multidrug resistance protein MdtK NorM%3B MdtK%3B functions as a Na(+)/drug antiporter%3B inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones gene gene1817 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09120 UM146_RS09125 UM146_08835 UM146_RS09125 1864278 1864919 + riboflavin synthase catalyzes the formation of riboflavin from 6%2C7-dimethyl-8-(1-D-ribityl)lumazine gene gene1818 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09125 UM146_RS09130 UM146_08840 UM146_RS09130 1864959 1866107 - cyclopropane-fatty-acyl-phospholipid synthase catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge gene gene1819 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09130 UM146_RS09135 UM146_08845 UM146_RS09135 1866398 1867609 - Bcr/CflA family drug resistance efflux transporter uncharacterized member of the major facilitator superfamily (MFS) gene gene1820 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09135 UM146_RS09140 UM146_08850 UM146_RS09140 1867722 1868654 + LysR family transcriptional regulator gene gene1821 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09140 UM146_RS09145 UM146_08855 UM146_RS09145 1868651 1869676 - PurR family transcriptional regulator binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis%3B is involved in regulation of purB%2C purC%2C purEK%2C purHD%2C purL%2C purMN and guaBA expression%3B binds hypoxanthine and guanine as inducers gene gene1822 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09145 UM146_RS09150 UM146_08860 UM146_RS09150 1869975 1870064 + stress response membrane gene gene1823 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09150 UM146_RS09155 UM146_08865 UM146_RS09155 1870230 1871399 + transporter gene gene1824 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09155 UM146_RS09160 UM146_08870 UM146_RS09160 1871545 1872126 - superoxide dismutase [Fe] SodB%3B iron binding%3B present under aerobic and anaerobic conditions%3B destroys free radicals gene gene1825 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09160 UM146_RS09165 UM146_08875 UM146_RS09165 1872254 1873069 - endopeptidase gene gene1826 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09165 UM146_RS09170 UM146_08880 UM146_RS09170 1873404 1873751 + glutaredoxin gene gene1827 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09170 UM146_RS09175 UM146_08885 UM146_RS09175 1873887 1874030 - endonuclease gene gene1828 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09175 UM146_RS09180 UM146_08890 UM146_RS09180 1874123 1874770 - ribonuclease T Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) gene gene1829 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09180 UM146_RS09185 UM146_08895 UM146_RS09185 1874873 1875280 - glyoxalase I Ni-dependent%3B catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione gene gene1830 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09185 UM146_RS09190 UM146_08900 UM146_RS09190 1875361 1876458 - N-ethylmaleimide reductase FMN-linked%3B catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide gene gene1831 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09190 UM146_RS09195 UM146_08905 UM146_RS09195 1876495 1877094 - transcriptional regulator represses nemA which is involved in degradation of N-ethylmaleimide gene gene1832 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09195 UM146_RS09200 UM146_RS09200 UM146_RS09200 1877197 1877436 + hypothetical protein gene gene1833 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09200 UM146_RS09205 UM146_08915 UM146_RS09205 1877485 1878381 + oxidoreductase gene gene1834 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09205 UM146_RS09210 UM146_08920 UM146_RS09210 1878462 1878983 + superoxide dismutase SodC%3B copper and zinc binding%3B converts superoxide radicals to hydrogen peroxide and water gene gene1835 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09210 UM146_RS09215 UM146_08925 UM146_RS09215 1878984 1880996 - fusaric acid resistance protein gene gene1836 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09215 UM146_RS09220 UM146_08930 UM146_RS09220 1880996 1881853 - membrane protein gene gene1837 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09220 UM146_RS09225 UM146_08935 UM146_RS09225 1881856 1882092 - membrane protein gene gene1838 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09225 UM146_RS09230 UM146_08940 UM146_RS09230 1882293 1882727 + SlyA family transcriptional regulator Transcription regulator that can both activate or repress expression gene gene1839 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09230 UM146_RS09235 UM146_08945 UM146_RS09235 1882774 1883241 - hypothetical protein gene gene1840 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09235 UM146_RS09240 UM146_08950 anmK anmK 1883515 1884624 + anhydro-N-acetylmuramic acid kinase catalyzes hydrolysis of 1%2C6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate%3B involved in murein recycling gene gene1841 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09240 UM146_RS09245 UM146_08955 UM146_RS09245 1884722 1885051 + lysozyme inhibitor MliC%3B membrane-bound lysozyme inhibitor of c-type lysozyme gene gene1842 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09245 UM146_RS09250 UM146_08960 UM146_RS09250 1885110 1885766 + pyridoxine/pyridoxamine 5'-phosphate oxidase catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate gene gene1843 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09250 UM146_RS09255 UM146_08965 UM146_RS09255 1885895 1887169 + tyrosine--tRNA ligase gene gene1844 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09255 UM146_RS09260 UM146_08970 UM146_RS09260 1887231 1888091 + pyridoxamine kinase catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal gene gene1845 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09260 UM146_RS09265 UM146_08975 UM146_RS09265 1888135 1888740 - glutathionine S-transferase gene gene1846 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09265 UM146_RS09270 UM146_08980 tppB tppB 1888845 1890347 - dipeptide and tripeptide permease A mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium%3B member of proton-dependent oligopeptide transport (POT) system family%3B in Escherichia coli this gene is regulated by OmpR although not via osmoregulation gene gene1847 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09270 UM146_RS09275 UM146_08985 UM146_RS09275 1890630 1890830 - hypothetical protein gene gene1848 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09275 UM146_RS09280 UM146_08990 UM146_RS09280 1890958 1891593 - endonuclease III DNA-(apurinic or apyrimidinic site) lyase%3B has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity%3B removed damaged DNA at cytosines%2C thymines and guanines gene gene1849 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09280 UM146_RS09285 UM146_08995 UM146_RS09285 1891593 1892288 - electron transporter RsxE gene gene1850 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09285 UM146_RS09290 UM146_09000 UM146_RS09290 1892292 1892912 - electron transport complex protein RsxA part of membrane-bound complex hought to be involved in electron transport to nitrogen gene gene1851 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09290 UM146_RS09295 UM146_09005 rnfD rnfD 1892916 1893974 - electron transport complex subunit RsxD RnfD%3B RsxD%3B required for nitrogen fixation in Rhodobacter capsulatus%3B part of a membrane-bound complex thought to be involved in electron transport to nitrogenase%3B in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents gene gene1852 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09295 UM146_RS09300 UM146_09010 UM146_RS09300 1893975 1896101 - electron transporter RsxC part of membrane-bound complex thought to be involved in electron transport to nitrogen gene gene1853 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09300 UM146_RS09305 UM146_09015 UM146_RS09305 1896094 1896672 - electron transport complex subunit RsxB part of membrane-bound complex thought to be involved in electron transport to nitrogen gene gene1854 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09305 UM146_RS09310 UM146_09020 UM146_RS09310 1896672 1897253 - electron transport complex subunit RsxA gene gene1855 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09310 UM146_RS09315 UM146_09025 UM146_RS09315 1897330 1897770 - membrane protein gene gene1856 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09315 UM146_RS09320 UM146_09030 UM146_RS09320 1897856 1898071 - nucleoid-associated protein YdgT%3B in E. coli%2C when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC%3B seems to play a role in optimizing the activity of oriC%3B non-essential%3B Hha protein paralog%3B in an hha mutant background%2C cnu is overexpressed and can compensate hha-induced phenotypes gene gene1857 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09320 UM146_RS09325 UM146_RS09325 UM146_RS09325 1898344 1898499 - beta-lactam resistance protein gene gene1858 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09325 UM146_RS09330 UM146_09035 UM146_RS09330 1898712 1899752 + oxidoreductase gene gene1859 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09330 UM146_RS09335 UM146_09040 UM146_RS09335 1899788 1900789 - adenosine deaminase gene gene1860 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09335 UM146_RS09340 UM146_09045 UM146_RS09340 1900893 1902065 - aminotransferase catalyzes the formation of homocysteine and pyruvate from cystathionine%3B also acts a a negative regulator for the mal regulon but interacting with the transcriptional activator MalT gene gene1861 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09340 UM146_RS09345 UM146_09050 UM146_RS09345 1902075 1903667 - PTS maltose- and glucose EIICB component phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%3B catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane%3B component IIB catalyzes the phosphorylation of the sugar molecule%3B IIC forms the translocation channel and contains the substrate specific binding site gene gene1862 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09345 UM146_RS09350 UM146_09055 UM146_RS09350 1903842 1904870 + LacI family transcriptional regulator regulates malXY which are involved in maltose-glucose transport gene gene1863 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09350 UM146_RS09355 UM146_09060 UM146_RS09355 1904982 1905749 + 7-alpha-hydroxysteroid dehydrogenase Acts on the hydroxyl group at position 7 of the steroid frame gene gene1864 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09355 UM146_RS09360 UM146_09065 UM146_RS09360 1905978 1906568 + transcriptional regulator gene gene1865 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09360 UM146_RS09365 UM146_09070 UM146_RS09365 1906958 1908769 + beta-D-glucuronidase gene gene1866 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09365 UM146_RS09370 UM146_09075 UM146_RS09370 1908766 1910139 + glucuronide transporter gene gene1867 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09370 UM146_RS09375 UM146_09080 UM146_RS09375 1910178 1911443 + porin gene gene1868 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09375 UM146_RS09380 UM146_09085 UM146_RS09380 1911488 1912996 - hypothetical protein gene gene1869 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09380 UM146_RS09385 UM146_09090 UM146_RS09385 1913097 1914272 - mannose-6-phosphate isomerase catalyzes the formation of of fructose 6-phosphate from mannose 6-phosphate gene gene1870 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09385 UM146_RS09390 UM146_09095 UM146_RS09390 1914471 1916117 + fumarate hydratase class I%2C aerobic catalyzes the formation of malate from fumerate gene gene1871 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09390 UM146_RS09395 UM146_09100 fumC fumC 1916260 1917663 + fumarate hydratase class II family (does not require metal)%3B tetrameric enzyme%3B fumarase C%3B reversibly converts (S)-malate to fumarate and water%3B functions in the TCA cycle gene gene1872 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09395 UM146_RS09400 UM146_09105 UM146_RS09400 1917660 1918589 - DNA replication terminus site-binding protein binds to DNA replication terminator sequences to prevent passage of replication forks gene gene1873 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09400 UM146_RS09405 UM146_RS09405 UM146_RS09405 1918665 1919965 - sensor protein RstB gene gene1874 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09405 UM146_RS09410 UM146_09120 UM146_RS09410 1919969 1920688 - two-component system response regulator response regulator in two-component regulatory system with RstB gene gene1875 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09410 UM146_RS09415 UM146_09125 UM146_RS09415 1920817 1921152 + membrane protein gene gene1876 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09415 UM146_RS09420 UM146_09135 UM146_RS09420 1921149 1921871 - dihydrofolate reductase FolM gene gene1877 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09420 UM146_RS09425 UM146_09140 UM146_RS09425 1921908 1923290 - arginine:ornithine antiporter gene gene1878 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09425 UM146_RS09430 UM146_09145 UM146_RS09430 1923476 1924420 - hypothetical protein gene gene1879 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09430 UM146_RS09435 UM146_09150 pntA pntA 1924944 1926476 + NAD(P) transhydrogenase subunit alpha forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane%3B involved in catalyzing transfer of hydride ion equivalents between NAD and NADP%3B stereospecific (AB-specific)%3B functions as a proton pump by translocating protons from cytoplasm to periplasm gene gene1880 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09435 UM146_RS09440 UM146_09155 pntB pntB 1926487 1927875 + NAD(P) transhydrogenase subunit beta catalyzes reversible transfer of hydride ion equivalent between NAD and NADP%3B membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane%3B forms a tetramer composed of two alpha and 2 beta subunits%3B AB-stereospecific enzyme gene gene1881 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09440 UM146_RS09445 UM146_09160 tqsA tqsA 1927900 1928934 - AI-2 transporter TqsA transport of quorum-sensing signal%3B mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes gene gene1882 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09445 UM146_RS09450 UM146_09165 UM146_RS09450 1929345 1929710 + spermidine export protein MdtJ with MdtI is involved in resistance to deoxycholate%2C nalidixic acid%2C fosfomycin%2C and SDS gene gene1883 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09450 UM146_RS09455 UM146_09170 UM146_RS09455 1929697 1930026 + spermidine export protein MdtI with MdtJ is involved in resistance to deoxycholate%2C nalidixic acid%2C fosfomycin%2C and SDS gene gene1884 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09455 UM146_RS09460 UM146_09175 UM146_RS09460 1930065 1930886 - serine protease gene gene1885 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09460 UM146_RS09465 UM146_RS09465 UM146_RS09465 1930986 1931069 - hypothetical protein gene gene1886 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09465 UM146_RS09470 UM146_09180 UM146_RS09470 1931162 1931497 - acid-shock protein required for growth and survival under moderately acid conditions gene gene1887 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09470 UM146_RS09475 UM146_09185 UM146_RS09475 1931895 1933148 - hypothetical protein gene gene1888 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09475 UM146_RS09480 UM146_09190 UM146_RS09480 1933255 1934148 + LysR family transcriptional regulator gene gene1889 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09480 UM146_RS09485 UM146_09195 UM146_RS09485 1934283 1935503 + transcriptional regulator mlc%2C controls the expression of genes involved in the phosphotransferase and phosphoenolpyruvate systems%2C regulates genes involved in the uptake of sugars gene gene1890 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09485 UM146_RS09490 UM146_09200 UM146_RS09490 1935628 1936323 + dithiobiotin synthetase DTB synthetase%3B dethiobiotin synthase%3B involved in production of dethiobiotin from ATP and 7%2C8-diaminononanoate and carbon dioxide%3B contains magnesium gene gene1891 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09490 UM146_RS09495 UM146_09205 UM146_RS09495 1936276 1937457 - voltage-gated ClC-type chloride channel ClcB gene gene1892 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09495 UM146_RS09500 UM146_09210 UM146_RS09500 1937654 1938268 - twin-argninine leader-binding protein DmsD binds to the twin-arginine signal peptides of certain proteins%2C including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane gene gene1893 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09500 UM146_RS09505 UM146_09215 UM146_RS09505 1938311 1939165 - dimethyl sulfoxide reductase subunit H gene gene1894 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09505 UM146_RS09510 UM146_09220 UM146_RS09510 1939167 1939784 - dimethyl sulfoxide reductase oxidoreductase%2C Fe-S subunit%3B terminal electron transfer protein for the reduction of DMSO gene gene1895 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09510 UM146_RS09515 UM146_09225 UM146_RS09515 1939795 1942191 - dimethyl sulfoxide reductase subunit A gene gene1896 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09515 UM146_RS09520 UM146_RS09520 UM146_RS09520 1942279 1944704 - dimethyl sulfoxide reductase gene gene1897 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09520 UM146_RS09525 UM146_09240 UM146_RS09525 1944903 1945208 - membrane protein gene gene1898 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09525 UM146_RS09530 UM146_09245 UM146_RS09530 1945280 1946026 + lipoprotein gene gene1899 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09530 UM146_RS09535 UM146_09250 UM146_RS09535 1946029 1946589 - spermidine N1-acetyltransferase catalyzes the formation of N(1)- and N(8)-acetylspermidine from spermidine gene gene1900 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09535 UM146_RS09540 UM146_09255 UM146_RS09540 1946624 1946965 - hypothetical protein gene gene1901 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09540 UM146_RS09545 UM146_09260 UM146_RS09545 1947100 1947426 + membrane protein gene gene1902 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09545 UM146_RS09550 UM146_09265 UM146_RS09550 1947632 1948846 + starvation sensing protein RspA starvation-sensing protein%3B maybe involved in homoserine lactone degradation gene gene1903 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09550 UM146_RS09555 UM146_09270 UM146_RS09555 1948858 1949877 + oxidoreductase gene gene1904 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09555 UM146_RS09560 UM146_09275 UM146_RS09560 1950041 1950289 + MFS transporter gene gene1905 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09560 UM146_RS09565 UM146_09280 UM146_RS09565 1950378 1951838 + D-mannonate oxidoreductase gene gene1906 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09565 UM146_RS09570 UM146_09285 UM146_RS09570 1951874 1952077 - hypothetical protein gene gene1907 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09570 UM146_RS09575 UM146_09290 UM146_RS09575 1952254 1952940 - transcriptional regulator gene gene1908 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09575 UM146_RS09580 UM146_09295 UM146_RS09580 1953029 1953775 - NADP-dependent L-serine/L-allo-threonine dehydrogenase YdfG NADP(+)-dependent%3B catalyzes the formation of 3-hydroxypropionate from the toxic malonic semialdehyde%2C catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine%3B can also use 3-hydroxybutyrate%2C 3-hydroxy-isobutyrate%2C D-threonine%2C L-allo-threonine%2CD-serine gene gene1909 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09580 UM146_RS09585 UM146_09300 UM146_RS09585 1953912 1955957 + dipeptidyl carboxypeptidase II gene gene1910 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09585 UM146_RS09590 UM146_RS09590 UM146_RS09590 1956049 1956210 + hypothetical protein gene gene1911 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09590 UM146_RS09595 UM146_09310 UM146_RS09595 1956465 1957355 + diguanylate cyclase required for pgaD induction gene gene1912 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09595 UM146_RS09600 UM146_09315 UM146_RS09600 1957574 1957669 - hypothetical protein gene gene1913 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09600 UM146_RS09605 UM146_09320 UM146_RS09605 1957796 1958983 - transporter YdeF%3B uncharacterized member of the major facilitator superfamily (MFS) of transporters gene gene1914 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09605 UM146_RS09610 UM146_09325 UM146_RS09610 1959178 1960077 + O-acetylserine/cysteine export protein gene gene1915 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09610 UM146_RS09615 UM146_09330 UM146_RS09615 1960122 1960820 - transcriptional regulator gene gene1916 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09615 UM146_RS09620 UM146_09335 UM146_RS09620 1961019 1961330 + PTS lactose transporter subunit IIB gene gene1917 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09620 UM146_RS09625 UM146_09340 UM146_RS09625 1961445 1962767 + PTS cellobiose transporter subunit IIC gene gene1918 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09625 UM146_RS09630 UM146_09345 UM146_RS09630 1962795 1963106 + molecular chaperone TorD gene gene1919 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09630 UM146_RS09635 UM146_09350 UM146_RS09635 1963161 1964834 + porin gene gene1920 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09635 UM146_RS09640 UM146_09355 UM146_RS09640 1964858 1966297 + 6-phospho-beta-glucosidase gene gene1921 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09640 UM146_RS09645 UM146_09360 UM146_RS09645 1966354 1966572 - hypothetical protein gene gene1922 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09645 UM146_RS09650 UM146_09365 UM146_RS09650 1966604 1966993 - MDR efflux pump AcrAB transcriptional activator MarA transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype%3B also activates sodA%2C zwf and micF gene gene1923 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09650 UM146_RS09655 UM146_09370 UM146_RS09655 1967008 1967442 - transcriptional regulator Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes gene gene1924 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09655 UM146_RS09660 UM146_09375 UM146_RS09660 1967654 1968319 + membrane protein gene gene1925 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09660 UM146_RS09665 UM146_09380 UM146_RS09665 1968344 1969534 - sugar efflux transporter gene gene1926 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09665 UM146_RS09670 UM146_09385 UM146_RS09670 1969873 1970754 - LysR family transcriptional regulator gene gene1927 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09670 UM146_RS09675 UM146_09390 UM146_RS09675 1970855 1972243 + succinate dehydrogenase gene gene1928 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09675 UM146_RS09680 UM146_09395 UM146_RS09680 1972307 1973233 + glutaminase 2 catalyzes the formation of glutamate from glutamine gene gene1929 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09680 UM146_RS09685 UM146_09400 UM146_RS09685 1973233 1973592 + hypothetical protein gene gene1930 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09685 UM146_RS09690 UM146_09405 UM146_RS09690 1973731 1975149 + diguanylate cyclase gene gene1931 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09690 UM146_RS09695 UM146_09410 UM146_RS09695 1975376 1976827 + altronate oxidoreductase catalyzes the formation of D-tagaturonate from D-altronate gene gene1932 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09695 UM146_RS09700 UM146_RS09700 UM146_RS09700 1976874 1977074 - hypothetical protein gene gene1933 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09700 UM146_RS09705 UM146_09415 UM146_RS09705 1977024 1977938 + hypothetical protein gene gene1934 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09705 UM146_RS09710 UM146_09420 UM146_RS09710 1977942 1978700 - trans-aconitate 2-methyltransferase catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate gene gene1935 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09710 UM146_RS09715 UM146_09425 UM146_RS09715 1979008 1979274 + antitoxin gene gene1936 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09715 UM146_RS09720 UM146_09430 UM146_RS09720 1979274 1980560 + serine/threonine protein kinase gene gene1937 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09720 UM146_RS09725 UM146_09435 UM146_RS09725 1980781 1981260 - hypothetical protein gene gene1938 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09725 UM146_RS09730 UM146_09440 UM146_RS09730 1981260 1981535 - hypothetical protein gene gene1939 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09730 UM146_RS09735 UM146_09445 UM146_RS09735 1981564 1981986 - hypothetical protein gene gene1940 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09735 UM146_RS09740 UM146_09450 UM146_RS09740 1982075 1982257 - hypothetical protein gene gene1941 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09740 UM146_RS09745 UM146_09455 UM146_RS09745 1982427 1983479 + hypothetical protein gene gene1942 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09745 UM146_RS09750 UM146_09460 UM146_RS09750 1983491 1983808 + DNA-binding protein gene gene1943 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09750 UM146_RS09760 UM146_09465 UM146_RS09760 1984012 1984254 + phage capsid protein gene gene1944 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09760 UM146_RS09765 UM146_09470 UM146_RS09765 1984301 1985593 + attachment protein gene gene1945 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09765 UM146_RS09770 UM146_09475 UM146_RS09770 1985593 1985934 + minor coat protein gene gene1946 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09770 UM146_RS09775 UM146_09480 UM146_RS09775 1985935 1987029 + hypothetical protein gene gene1947 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09775 UM146_RS09780 UM146_09485 UM146_RS09780 1987037 1988302 + general secretion pathway protein GspD gene gene1948 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09780 UM146_RS09785 UM146_09490 UM146_RS09785 1988372 1988680 + hypothetical protein gene gene1949 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09785 UM146_RS09790 UM146_09495 UM146_RS09790 1988798 1989031 + hypothetical protein gene gene1950 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09790 UM146_RS09795 UM146_RS09795 UM146_RS09795 1989250 1989507 - hypothetical protein gene gene1951 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09795 UM146_RS09800 UM146_09505 UM146_RS09800 1989617 1990399 + NAD-dependent dehydratase gene gene1952 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09800 UM146_RS09805 UM146_09510 UM146_RS09805 1990525 1990647 + hypothetical protein gene gene1953 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09805 UM146_RS09810 UM146_09515 UM146_RS09810 1991175 1991738 + Fml fimbriae subunit gene gene1954 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09810 UM146_RS09815 UM146_09520 UM146_RS09815 1992100 1992810 + fimbrial chaperone protein FimC involved in type 1 fimbriae biosynthesis%2C interacts with FimH gene gene1955 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09815 UM146_RS09820 UM146_09525 UM146_RS09820 1992852 1995503 + fimbrial protein FimD gene gene1956 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09820 UM146_RS09825 UM146_09530 UM146_RS09825 1995517 1996047 + fimbrial protein gene gene1957 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09825 UM146_RS09830 UM146_09535 UM146_RS09830 1996060 1996563 + fimbrial protein gene gene1958 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09830 UM146_RS09835 UM146_09540 UM146_RS09835 1996623 1997537 + fimbrial protein FimH gene gene1959 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09835 UM146_RS09840 UM146_09545 UM146_RS09840 1997875 2000154 + oxidoreductase in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell%3B involved with increased resistance to low pH%3B member of the prokaryotic molybdopterin-containing oxidoreductase family gene gene1960 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09840 UM146_RS09845 UM146_09550 UM146_RS09845 2000402 2000599 + two-component-system connector protein SafA gene gene1961 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09845 UM146_RS09850 UM146_09555 UM146_RS09850 2000674 2001435 + AraC family transcriptional regulator regulates the cellular response to acid resistance gene gene1962 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09850 UM146_RS09855 UM146_09560 UM146_RS09855 2001837 2003519 + sulfatase gene gene1963 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09855 UM146_RS09860 UM146_09565 UM146_RS09860 2003571 2004728 + anaerobic sulfatase maturase gene gene1964 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09860 UM146_RS09865 UM146_09575 UM146_RS09865 2005019 2006704 + multidrug ABC transporter ATP-binding protein gene gene1965 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09865 UM146_RS09870 UM146_09580 UM146_RS09870 2006742 2009114 + hypothetical protein gene gene1966 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09870 UM146_RS09875 UM146_09585 UM146_RS09875 2009171 2011954 + zinc protease gene gene1967 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09875 UM146_RS09880 UM146_09590 UM146_RS09880 2012161 2012304 + hypothetical protein gene gene1968 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09880 UM146_RS09885 UM146_09595 UM146_RS09885 2012315 2013715 + glutamate decarboxylase beta gene gene1969 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09885 UM146_RS09890 UM146_09600 UM146_RS09890 2013871 2015406 + antiporter gene gene1970 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09890 UM146_RS09895 UM146_09605 UM146_RS09895 2015702 2016856 + hypothetical protein gene gene1971 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09895 UM146_RS09900 UM146_09610 UM146_RS09900 2017180 2017398 + diguanylate cyclase gene gene1972 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09900 UM146_RS09905 UM146_09615 UM146_RS09905 2017399 2019822 + diguanylate phosphodiesterase heme-regulated phosphodiesterase with phosphodiesterase activity with cGMP%3B cold- and stationary phase-induced bioflim regulator%3B oxygen sensor gene gene1973 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09905 UM146_RS09910 UM146_09620 UM146_RS09910 2020012 2020443 - peroxiredoxin OsmC gene gene1974 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09910 UM146_RS09915 UM146_09625 UM146_RS09915 2020788 2021003 + protein bdm gene gene1975 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09915 UM146_RS09920 UM146_09630 rpsV rpsV 2021105 2021242 + stationary-phase-induced ribosome-associated protein protein D%3B stationary-phase-induced ribosome-associated%3B in Escherichia coli this protein becomes associated with the ribosome%3B expression increases during stationary phase gene gene1976 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09920 UM146_RS09925 UM146_09635 UM146_RS09925 2021398 2023095 + NAD-dependent malic enzyme gene gene1977 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09925 UM146_RS09930 UM146_09640 adhP adhP 2023229 2024239 + alcohol dehydrogenase similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs gene gene1978 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09930 UM146_RS09935 UM146_09645 UM146_RS09935 2024425 2024703 + hypothetical protein gene gene1979 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09935 UM146_RS09940 UM146_09650 UM146_RS09940 2024703 2024987 + transcriptional regulator gene gene1980 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09940 UM146_RS09945 UM146_09655 UM146_RS09945 2025216 2025869 - formate dehydrogenase-N subunit gamma cytochrome b556(FDO) component%3B heme containing gene gene1981 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09945 UM146_RS09950 UM146_09660 UM146_RS09950 2025862 2026746 - formate dehydrogenase-N subunit beta beta subunit%3B involved in the use of formate as an electron donor during aerobic respiration%3B acts to transfer electrons from the major(alpha subunit) to the cytochrome b556(gamma subunit) gene gene1982 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09950 UM146_RS09955 UM146_09665 UM146_RS09955 2026759 2029170 - formate dehydrogenase subunit alpha gene gene1983 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09955 UM146_RS09960 UM146_09670 UM146_RS09960 2029219 2029806 - sulfate ABC transporter substrate-binding protein gene gene1984 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09960 UM146_RS09965 UM146_09675 UM146_RS09965 2030095 2030919 + aromatic amino acid exporter gene gene1985 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09965 UM146_RS09970 UM146_09680 UM146_RS09970 2031191 2032579 + nitrite extrusion protein 2 involved in the transport of nitrate and nitrite gene gene1986 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09970 UM146_RS09975 UM146_09685 narZ narZ 2032674 2036414 + nitrate reductase A subunit alpha with NarYV catalyzes the reduction of nitrate%3B the beta subunit is an iron sulfur cluster containing electron transfer subunit%3B one of 3 nitrate reductases in E. coli%3B expression of nitrate reductase Z is not dependent on nitrate levels gene gene1987 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09975 UM146_RS09980 UM146_09690 narH narH 2036411 2037955 + nitrate reductase A subunit beta with NarGJI catalyzes the reduction of nitrate%3B the beta subunit is an iron sulfur cluster containing electron transfer subunit%3B one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high gene gene1988 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09980 UM146_RS09985 UM146_09695 UM146_RS09985 2037955 2038650 + nitrate reductase molybdenum cofactor assembly chaperone NarJ delta subunit of nitrate reductase 1%3B chaperone for the insertion of the molybdenum cofactor and assembly of nitrate reductase 1 gene gene1989 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09985 UM146_RS09990 UM146_09700 narI narI 2038647 2039327 + nitrate reductase A subunit gamma with NarGJH catalyzes the reduction of nitrate%3B the gamma subunit localizes NarGHI to the membrane%3B one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high gene gene1990 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09990 UM146_RS09995 UM146_09705 UM146_RS09995 2039407 2040300 + hypothetical protein gene gene1991 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS09995 UM146_RS10000 UM146_09710 UM146_RS10000 2040396 2041241 - N-hydroxyarylamine O-acetyltransferase catalyzes the addition of the acetyl moity of acetyl-CoA to an N-hydroxy-arylamine to form an N-acetoxyarylamine gene gene1992 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10000 UM146_RS10005 UM146_09715 UM146_RS10005 2041416 2041985 + hypothetical protein gene gene1993 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10005 UM146_RS10010 UM146_RS10010 UM146_RS10010 2042051 2042215 - hypothetical protein gene gene1994 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10010 UM146_RS10015 UM146_09720 UM146_RS10015 2042302 2042517 - acetyltransferase gene gene1995 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10015 UM146_RS10020 UM146_09725 UM146_RS10020 2042595 2042738 - hypothetical protein gene gene1996 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10020 UM146_RS10025 UM146_RS10025 UM146_RS10025 2042851 2043635 - hypothetical protein gene gene1997 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10025 UM146_RS10030 UM146_09740 UM146_RS10030 2043688 2044449 - peptidase M35 gene gene1998 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10030 UM146_RS10035 UM146_09745 UM146_RS10035 2044495 2046843 - type IV secretion protein Rhs gene gene1999 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10035 UM146_RS10040 UM146_09750 UM146_RS10040 2046862 2047146 - hypothetical protein gene gene2000 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10040 UM146_RS10045 UM146_09755 UM146_RS10045 2047687 2048097 - glutathione S-transferase gene gene2001 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10045 UM146_RS10050 UM146_09760 UM146_RS10050 2048111 2048287 - glutathione S-transferase gene gene2002 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10050 UM146_RS10055 UM146_09765 UM146_RS10055 2048554 2050053 + L-asparagine permease involved in the transporte of L-asparagine gene gene2003 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10055 UM146_RS10060 UM146_09770 UM146_RS10060 2050166 2051227 - hypothetical protein gene gene2004 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10060 UM146_RS10065 UM146_09775 UM146_RS10065 2051469 2053571 + TonB-dependent receptor gene gene2005 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10065 UM146_RS10070 UM146_09780 UM146_RS10070 2053609 2053845 - GntR family transcriptional regulator gene gene2006 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10070 UM146_RS10075 UM146_09785 UM146_RS10075 2054052 2054570 + L-amino acid N-acyltransferase MnaT gene gene2007 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10075 UM146_RS10080 UM146_09790 UM146_RS10080 2054567 2055016 + membrane protein gene gene2008 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10080 UM146_RS10085 UM146_09795 UM146_RS10085 2055017 2055250 - hypothetical protein gene gene2009 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10085 UM146_RS10090 UM146_09800 UM146_RS10090 2055336 2055508 - hypothetical protein gene gene2010 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10090 UM146_RS10095 UM146_RS10095 UM146_RS10095 2055667 2055864 - hypothetical protein gene gene2011 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10095 UM146_RS10100 UM146_09805 UM146_RS10100 2055895 2057319 - gamma-aminobutyraldehyde dehydrogenase catalyzes the formation of 4-aminobutanoate from 4-aminobutanal%3B involved in putrescine degradation gene gene2012 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10100 UM146_RS10105 UM146_09810 UM146_RS10105 2057341 2058135 - ABC transporter permease gene gene2013 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10105 UM146_RS10110 UM146_09815 UM146_RS10110 2058125 2059066 - spermidine/putrescine ABC transporter permease gene gene2014 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10110 UM146_RS10115 UM146_09820 UM146_RS10115 2059067 2060080 - polyamine ABC transporter ATP-binding protein gene gene2015 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10115 UM146_RS10120 UM146_09825 UM146_RS10120 2060098 2061243 - spermidine/putrescine ABC transporter substrate-binding protein gene gene2016 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10120 UM146_RS10125 UM146_09830 UM146_RS10125 2061488 2062894 - GntR family transcriptional regulator gene gene2017 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10125 UM146_RS10130 UM146_RS10130 UM146_RS10130 2062973 2063208 - antitoxin gene gene2018 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10130 UM146_RS10135 UM146_RS10135 UM146_RS10135 2063447 2063617 + hypothetical protein gene gene2019 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10135 UM146_RS10140 UM146_09840 UM146_RS10140 2063709 2065670 - protease gene gene2020 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10140 UM146_RS10145 UM146_09845 UM146_RS10145 2065743 2066279 - XRE family transcriptional regulator gene gene2021 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10145 UM146_RS10150 UM146_RS10150 UM146_RS10150 2066371 2067542 + hypothetical protein gene gene2022 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10150 UM146_RS10155 UM146_09860 UM146_RS10155 2067577 2068245 - lipoprotein gene gene2023 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10155 UM146_RS10160 UM146_09865 UM146_RS10160 2068548 2069141 - tellurite resistance methyltransferase TehB with TehA confers resistance to tellurite gene gene2024 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10160 UM146_RS10165 UM146_09870 UM146_RS10165 2069138 2070130 - tellurite resistance protein TehA gene gene2025 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10165 UM146_RS10170 UM146_09875 UM146_RS10170 2070254 2071234 + acetyltransferase gene gene2026 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10170 UM146_RS10175 UM146_09880 UM146_RS10175 2071226 2071765 - ribosomal-protein-L7/L12-serine acetyltransferase gene gene2027 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10175 UM146_RS10180 UM146_09885 UM146_RS10180 2071828 2072052 - hypothetical protein gene gene2028 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10180 UM146_RS10185 UM146_09890 UM146_RS10185 2072068 2072271 + hypothetical protein gene gene2029 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10185 UM146_RS10190 UM146_09895 mdoD mdoD 2072192 2073847 - glucan biosynthesis protein D involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans gene gene2030 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10190 UM146_RS10195 UM146_09900 UM146_RS10195 2074072 2075415 - hypothetical protein gene gene2031 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10195 UM146_RS10200 UM146_09905 UM146_RS10200 2075632 2076555 + LysR family transcriptional regulator gene gene2032 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10200 UM146_RS10210 UM146_RS10210 UM146_RS10210 2076885 2077148 + endonuclease gene gene2034 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10210 UM146_RS10215 UM146_09915 UM146_RS10215 2077221 2077394 - hypothetical protein gene gene2035 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10215 UM146_RS10220 UM146_09920 UM146_RS10220 2077639 2078169 - cytochrome B561 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm gene gene2036 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10220 UM146_RS10225 UM146_09925 UM146_RS10225 2078358 2079359 + glyceraldehyde-3-phosphate dehydrogenase NAD-dependent%3B catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate%3B active during glycolysis gene gene2037 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10225 UM146_RS10230 UM146_09930 UM146_RS10230 2079401 2080840 - aldehyde dehydrogenase NAD-linked gene gene2038 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10230 UM146_RS10235 UM146_09935 UM146_RS10235 2081037 2081837 - hypothetical protein gene gene2039 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10235 UM146_RS10240 UM146_09940 UM146_RS10240 2082110 2086012 - ATP-dependent RNA helicase HrpA involved in the post-transcriptional processing of the daa operon mRNA%2C which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain gene gene2040 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10240 UM146_RS10245 UM146_09945 UM146_RS10245 2086213 2086818 + FMN-dependent NADH-azoreductase FMN-dependent%3B requires NADH%3B catalyzes the cleavage of azo bond in aromatic azo compounds gene gene2041 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10245 UM146_RS10250 UM146_09950 UM146_RS10250 2086872 2088164 - hypothetical protein gene gene2042 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10250 UM146_RS10255 UM146_09955 UM146_RS10255 2088178 2089935 - hypothetical protein gene gene2043 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10255 UM146_RS10260 UM146_09960 UM146_RS10260 2089951 2090847 - hypothetical protein gene gene2044 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10260 UM146_RS10265 UM146_09965 UM146_RS10265 2090847 2091452 - membrane protein gene gene2045 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10265 UM146_RS10270 UM146_09970 UM146_RS10270 2091751 2092611 - oxidoreductase gene gene2046 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10270 UM146_RS10275 UM146_RS10275 UM146_RS10275 2092831 2094822 - hypothetical protein gene gene2047 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10275 UM146_RS10285 UM146_RS10285 UM146_RS10285 2097801 2098100 - hypothetical protein gene gene2048 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10285 UM146_RS10290 UM146_RS10290 UM146_RS10290 2098060 2098272 - hypothetical protein gene gene2049 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10290 UM146_RS10295 UM146_RS10295 UM146_RS10295 2098505 2099254 - hypothetical protein gene gene2050 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10295 UM146_RS10300 UM146_09995 UM146_RS10300 2099915 2100241 - hypothetical protein gene gene2051 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10300 UM146_RS10305 UM146_10000 UM146_RS10305 2100249 2100434 - lipoprotein gene gene2052 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10305 UM146_RS10310 UM146_10005 UM146_RS10310 2100431 2103070 - hypothetical protein gene gene2053 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10310 UM146_RS10315 UM146_10010 UM146_RS10315 2103278 2104267 + lactate dehydrogenase fermentative%3B catalyzes the formationof pyruvate from lactate gene gene2054 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10315 UM146_RS10320 UM146_10015 UM146_RS10320 2104378 2104800 + heat-inducible protein gene gene2055 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10320 UM146_RS10325 UM146_10020 UM146_RS10325 2104797 2105063 - DUF333 domain-containing protein gene gene2056 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10325 UM146_RS10330 UM146_10030 UM146_RS10330 2105337 2108861 + pyruvate-flavodoxin oxidoreductase gene gene2057 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10330 UM146_RS10335 UM146_10035 UM146_RS10335 2109227 2110360 + porin allows for ions and hydrophilic solutes to cross the outer membrane gene gene2058 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10335 UM146_RS10340 UM146_10040 UM146_RS10340 2110501 2110935 + universal stress protein F gene gene2059 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10340 UM146_RS10345 UM146_RS10345 UM146_RS10345 2111029 2111148 - hypothetical protein gene gene2060 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10345 UM146_RS10350 UM146_10045 UM146_RS10350 2111172 2111393 + hypothetical protein gene gene2061 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10350 UM146_RS10360 UM146_10050 UM146_RS10360 2113069 2113209 + integrase gene gene2062 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10360 UM146_RS10365 UM146_10055 UM146_RS10365 2113261 2114196 + tRNA 2-thiocytidine biosynthesis protein TtcA TtcA%3B YdaO%3B catalyzes the thiolation of cytosine 32 in specific tRNAs%3B forms 2-thiocytidine (s(2)C) gene gene2063 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10365 UM146_RS10370 UM146_10060 UM146_RS10370 2114325 2115698 - RNA helicase exhibits an RNA-dependent ATPase activity%2C specifically stimulated by bacterial 23S rRNA gene gene2064 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10370 UM146_RS10375 UM146_RS10375 UM146_RS10375 2115728 2115901 - hypothetical protein gene gene2065 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10375 UM146_RS10380 UM146_10065 zntB zntB 2116176 2117159 - zinc transporter ZntB gene gene2066 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10380 UM146_RS10385 UM146_10070 UM146_RS10385 2117414 2118646 + diguanylate cyclase gene gene2067 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10385 UM146_RS10390 UM146_10075 UM146_RS10390 2118667 2119230 - DNA endonuclease SmrA gene gene2068 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10390 UM146_RS10395 UM146_10080 UM146_RS10395 2119425 2120939 - MFS transporter gene gene2069 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10395 UM146_RS10400 UM146_10085 UM146_RS10400 2120936 2121964 - hemolysin D gene gene2070 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10400 UM146_RS10405 UM146_10090 UM146_RS10405 2122061 2122876 + AraC family transcriptional regulator gene gene2071 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10405 UM146_RS10410 UM146_RS10410 UM146_RS10410 2122858 2122977 + glutamate decarboxylase gene gene2072 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10410 UM146_RS10415 UM146_RS10415 UM146_RS10415 2123248 2123397 + pump protein gene gene2073 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10415 UM146_RS10420 UM146_10100 UM146_RS10420 2123408 2123923 + methylated-DNA--protein-cysteine methyltransferase gene gene2074 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10420 UM146_RS10425 UM146_10105 UM146_RS10425 2124118 2124870 + fumarate and nitrate reduction regulatory protein Global transcription factor that controls the expression of over 100 target genes in response to anoxia gene gene2075 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10425 UM146_RS10430 UM146_10110 UM146_RS10430 2125022 2125972 + universal stress protein E with UspC and UspD is involved in resistance to UV irradiation gene gene2076 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10430 UM146_RS10435 UM146_10115 UM146_RS10435 2126022 2126279 - DUF2534 domain-containing protein gene gene2077 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10435 UM146_RS10440 UM146_10120 UM146_RS10440 2126523 2127554 + mechanosensitive ion channel protein MscS gene gene2078 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10440 UM146_RS10445 UM146_10125 UM146_RS10445 2127605 2129218 - peptide ABC transporter substrate-binding protein is involved in the transport of the murein peptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate gene gene2079 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10445 UM146_RS10450 UM146_RS10450 UM146_RS10450 2129341 2129466 - hypothetical protein gene gene2080 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10450 UM146_RS10455 UM146_10130 UM146_RS10455 2129555 2130454 - LysR family transcriptional regulator gene gene2081 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10455 UM146_RS10460 UM146_10135 UM146_RS10460 2130592 2131512 + hypothetical protein gene gene2082 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10460 UM146_RS10465 UM146_10140 UM146_RS10465 2131583 2132221 + NAD-dependent dehydratase gene gene2083 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10465 UM146_RS10470 UM146_10145 UM146_RS10470 2132512 2133240 + murein peptide amidase A gene gene2084 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10470 UM146_RS10475 UM146_10150 UM146_RS10475 2133215 2134180 - L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-alanyl-D-glutamate to L-alanyl-L-glutamate gene gene2085 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10475 UM146_RS10480 UM146_10155 tpx tpx 2134299 2134805 + thiol peroxidase antioxidant activity%3B thioredoxin-dependent thiol peroxidase%3B forms homodimers in solution%3B shows substrate specificity to alkyl hydroperoxides%3B periplasmic protein gene gene2086 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10480 UM146_RS10485 UM146_10160 UM146_RS10485 2134849 2136390 - transcriptional regulator regulates genes involved in the biosynthesis and transport of aromatic amino acids gene gene2087 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10485 UM146_RS10490 UM146_10165 UM146_RS10490 2136538 2137599 - hypothetical protein gene gene2088 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10490 UM146_RS10495 UM146_10170 UM146_RS10495 2137596 2138993 - hypothetical protein gene gene2089 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10495 UM146_RS10500 UM146_10175 UM146_RS10500 2139149 2140147 + LacI family transcriptional regulator gene gene2090 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10500 UM146_RS10505 UM146_10180 UM146_RS10505 2140198 2141103 - membrane protein gene gene2091 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10505 UM146_RS10510 UM146_10185 UM146_RS10510 2141148 2142230 - sugar ABC transporter ATP-binding protein gene gene2092 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10510 UM146_RS10515 UM146_10190 UM146_RS10515 2142244 2142903 - beta-phosphoglucomutase catalyzes the interconversion of beta-D-glucose 6-phosphate to beta-D-glucose 1-phosphate gene gene2093 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10515 UM146_RS10520 UM146_10195 UM146_RS10520 2142900 2145167 - glycosyl hydrolase family 65 gene gene2094 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10520 UM146_RS10525 UM146_10200 UM146_RS10525 2145164 2146219 - oxidoreductase gene gene2095 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10525 UM146_RS10530 UM146_10205 UM146_RS10530 2146229 2147017 - hypothetical protein gene gene2096 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10530 UM146_RS10535 UM146_10210 UM146_RS10535 2147036 2148088 - alcohol dehydrogenase gene gene2097 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10535 UM146_RS10540 UM146_10215 UM146_RS10540 2148119 2148961 - sugar ABC transporter permease gene gene2098 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10540 UM146_RS10545 UM146_10220 UM146_RS10545 2148948 2149829 - ABC transporter permease gene gene2099 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10545 UM146_RS10550 UM146_10225 UM146_RS10550 2149850 2151142 - sugar ABC transporter substrate-binding protein gene gene2100 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10550 UM146_RS10555 UM146_10230 UM146_RS10555 2151156 2152835 - sucrose phosphorylase gene gene2101 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10555 UM146_RS10560 UM146_10235 UM146_RS10560 2153045 2153359 - thiosulfate--cyanide sulfurtransferase rhodanese%3B catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide gene gene2102 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10560 UM146_RS10565 UM146_10240 UM146_RS10565 2153434 2153655 - phage shock protein D gene gene2103 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10565 UM146_RS10570 UM146_10245 UM146_RS10570 2153664 2154023 - transcriptional regulator with PsbB forms toxin/antitoxin pair%3B activates the psp operon in response to phage infection%2C exposure to ethanol or osmotic shock gene gene2104 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10570 UM146_RS10575 UM146_10250 pspB pspB 2154023 2154247 - phage shock protein B DNA-binding transcriptional regulator%3B acts together with PspC to induce psp operon during infection with phage%2C exposure to ethanol or osmotic shock%3B forms a complex with PspA and C%3B PspC is required for PspAB binding gene gene2105 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10575 UM146_RS10580 UM146_10255 UM146_RS10580 2154301 2154969 - phage-shock protein involved in maintaining membrane potential under membrane stress conditions%3B also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF gene gene2106 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10580 UM146_RS10585 UM146_10260 pspF pspF 2155135 2156112 + transcriptional regulator transcriptional activator for pspABCE which are induced in response to phage proteins%2C membrane altering stresses%2C and impaired proton expor gene gene2107 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10585 UM146_RS10590 UM146_RS10590 UM146_RS10590 2156243 2156425 - hypothetical protein gene gene2108 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10590 UM146_RS10595 UM146_10265 UM146_RS10595 2156539 2156784 + hypothetical protein gene gene2109 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10595 UM146_RS10605 UM146_10270 UM146_RS10605 2157097 2158740 + peptide ABC transporter permease gene gene2110 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10605 UM146_RS10610 UM146_10275 UM146_RS10610 2158737 2159702 + peptide ABC transporter permease gene gene2111 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10610 UM146_RS10615 UM146_10280 UM146_RS10615 2159689 2160579 + peptide ABC transporter permease gene gene2112 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10615 UM146_RS10620 UM146_10285 UM146_RS10620 2160579 2161571 + peptide transport system ATP-binding protein SapD involved in resistance to antimibial peptides gene gene2113 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10620 UM146_RS10625 UM146_10290 UM146_RS10625 2161573 2162379 + peptide transport system ATP-binding protein SapF gene gene2114 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10625 UM146_RS10630 UM146_10295 UM146_RS10630 2162427 2163590 - Bcr/CflA family drug resistance efflux transporter gene gene2115 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10630 UM146_RS10635 UM146_10300 UM146_RS10635 2163599 2164972 - multidrug transporter gene gene2116 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10635 UM146_RS10640 UM146_10305 UM146_RS10640 2164976 2168082 - multidrug transporter gene gene2117 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10640 UM146_RS10645 UM146_10310 UM146_RS10645 2168082 2169203 - MexE family multidrug efflux RND transporter periplasmic adaptor subunit gene gene2118 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10645 UM146_RS10650 UM146_10315 UM146_RS10650 2169352 2169918 - TetR family transcriptional regulator gene gene2119 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10650 UM146_RS10655 UM146_10320 UM146_RS10655 2170396 2171184 + enoyl-ACP reductase [NADH] Catalyzes a key regulatory step in fatty acid biosynthesis gene gene2120 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10655 UM146_RS10660 UM146_10325 UM146_RS10660 2171329 2172456 + hypothetical protein gene gene2121 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10660 UM146_RS10665 UM146_10330 UM146_RS10665 2172524 2174458 + exoribonuclease 2 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction gene gene2122 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10665 UM146_RS10670 UM146_RS10670 UM146_RS10670 2174535 2174638 - hypothetical protein gene gene2123 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10670 UM146_RS10675 UM146_10335 UM146_RS10675 2174692 2176677 + RNase II stability modulator c-di-GMP phosphodiesterase%3B probably degrades signalling molecule c-di-GMP gene gene2124 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10675 UM146_RS10680 UM146_10340 UM146_RS10680 2176825 2176998 + hypothetical protein gene gene2125 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10680 UM146_RS10685 UM146_RS10685 UM146_RS10685 2177088 2177836 + DeoR faimly transcriptional regulator gene gene2126 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10685 UM146_RS10690 UM146_10355 UM146_RS10690 2178105 2178323 + osmotically-inducible lipoprotein B gene gene2127 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10690 UM146_RS10695 UM146_10360 UM146_RS10695 2178449 2178775 - translation initiation factor Sui1 involved in start site selection during the initiation of translation gene gene2128 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10695 UM146_RS10700 UM146_10365 UM146_RS10700 2178775 2179512 - orotidine 5'-phosphate decarboxylase gene gene2129 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10700 UM146_RS10705 UM146_10370 UM146_RS10705 2179702 2180871 - LPS assembly protein B gene gene2130 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10705 UM146_RS10710 UM146_10375 UM146_RS10710 2180878 2181186 - membrane protein gene gene2131 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10710 UM146_RS10715 UM146_10380 UM146_RS10715 2181335 2182099 - phosphatidylglycerophosphatase B gene gene2132 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10715 UM146_RS10720 UM146_10385 ribA ribA 2182269 2182859 + GTP cyclohydrolase-2 catalyzes the conversion of GTP to formate and 2%2C5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate gene gene2133 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10720 UM146_RS10725 UM146_10390 UM146_RS10725 2182923 2185598 - aconitate hydratase Catalyzes the conversion of citrate to isocitrate gene gene2134 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10725 UM146_RS10735 UM146_10395 UM146_RS10735 2185758 2185883 + hypothetical protein gene gene2135 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10735 UM146_RS10740 UM146_10400 UM146_RS10740 2185957 2186124 - hypothetical protein gene gene2136 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10740 UM146_RS10745 UM146_10405 UM146_RS10745 2186127 2186255 - hypothetical protein gene gene2137 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10745 UM146_RS10750 UM146_10410 cysB cysB 2186586 2187560 - transcriptional regulator LysR-type transcriptional regulator%3B contains helix-turn-helix (HTH) motif%3B in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon%3B autoregulates expression%3B crystal structure of Klebsiella aerogenes showed tetramer formation gene gene2138 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10750 UM146_RS10755 UM146_10415 UM146_RS10755 2187770 2190367 - DNA topoisomerase I catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining%2C maintains net negative superhelicity gene gene2139 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10755 UM146_RS10760 UM146_RS10760 UM146_RS10760 2190490 2190642 - hypothetical protein gene gene2140 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10760 UM146_RS10765 UM146_10420 UM146_RS10765 2190747 2190998 + hypothetical protein gene gene2141 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10765 UM146_RS10770 UM146_10425 UM146_RS10770 2191034 2192083 - peptidase multicopy suppressor of htrA(degP) gene gene2142 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10770 UM146_RS10775 UM146_RS10775 UM146_RS10775 2192095 2192259 + hypothetical protein gene gene2143 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10775 UM146_RS10780 UM146_10430 UM146_RS10780 2192303 2193061 + oxoacyl-ACP reductase gene gene2144 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10780 UM146_RS10785 UM146_10435 UM146_RS10785 2193058 2193648 + cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase catalyzes the formation of adenosylcobalamide from cobinamide and the formation of coenzyme B12 from cob(I)alamin gene gene2145 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10785 UM146_RS10790 UM146_10440 UM146_RS10790 2193687 2194562 - ribosomal large subunit pseudouridine synthase B catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA gene gene2146 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10790 UM146_RS10795 UM146_10445 UM146_RS10795 2194775 2196670 - hypothetical protein gene gene2147 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10795 UM146_RS10800 UM146_10450 UM146_RS10800 2196698 2197318 - RNA binding protein gene gene2148 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10800 UM146_RS10805 UM146_10455 UM146_RS10805 2197315 2198196 - S-adenosylmethionine tRNA ribosyltransferase gene gene2149 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10805 UM146_RS10810 UM146_10460 UM146_RS10810 2198470 2200032 + anthranilate synthase subunit I gene gene2150 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10810 UM146_RS10815 UM146_10465 UM146_RS10815 2200032 2201627 + anthranilate phosphoribosyltransferase bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase%3B TrpD%3B forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine%3B also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate%3B functions in tryptophan biosynthesis gene gene2151 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10815 UM146_RS10820 UM146_10470 UM146_RS10820 2201631 2202989 + phosphoribosylanthranilate isomerase monomeric bifunctional protein%3B functions in tryptophan biosynthesis pathway%3B phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate gene gene2152 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10820 UM146_RS10825 UM146_10475 UM146_RS10825 2203001 2204194 + tryptophan synthase subunit beta catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate gene gene2153 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10825 UM146_RS10830 UM146_10480 UM146_RS10830 2204194 2205000 + tryptophan synthase subunit alpha gene gene2154 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10830 UM146_RS10835 UM146_10485 UM146_RS10835 2205381 2205560 + hypothetical protein gene gene2155 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10835 UM146_RS10840 UM146_10490 UM146_RS10840 2205646 2206146 + hypothetical protein gene gene2156 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10840 UM146_RS10845 UM146_10495 UM146_RS10845 2206192 2206698 + hypothetical protein gene gene2157 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10845 UM146_RS10850 UM146_10505 UM146_RS10850 2207185 2207355 - phage protein gene gene2158 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10850 UM146_RS10855 UM146_10510 UM146_RS10855 2207470 2207739 - hypothetical protein gene gene2159 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10855 UM146_RS10860 UM146_10515 UM146_RS10860 2208032 2208463 + SAM-dependent methyltransferase gene gene2160 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10860 UM146_RS10865 UM146_10520 UM146_RS10865 2208518 2209102 - tail assembly protein gene gene2161 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10865 UM146_RS10870 UM146_RS10870 UM146_RS10870 2209102 2210844 - phage tail protein gene gene2162 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10870 UM146_RS10875 UM146_RS10875 UM146_RS10875 2210975 2211712 + hypothetical protein gene gene2163 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10875 UM146_RS10880 UM146_10530 UM146_RS10880 2212361 2212960 - hypothetical protein gene gene2164 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10880 UM146_RS10885 UM146_10535 UM146_RS10885 2213028 2216507 - host specificity protein J gene gene2165 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10885 UM146_RS10890 UM146_10540 UM146_RS10890 2216986 2217588 - tail protein gene gene2166 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10890 UM146_RS10895 UM146_10545 UM146_RS10895 2217525 2218124 - endopeptidase gene gene2167 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10895 UM146_RS10900 UM146_RS10900 UM146_RS10900 2218059 2218268 - hypothetical protein gene gene2168 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10900 UM146_RS10905 UM146_10550 UM146_RS10905 2218273 2218938 - tail protein gene gene2169 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10905 UM146_RS10910 UM146_10555 UM146_RS10910 2218970 2219299 - tail protein gene gene2170 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10910 UM146_RS10915 UM146_10560 UM146_RS10915 2219296 2221869 - tail protein gene gene2171 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10915 UM146_RS10920 UM146_10565 UM146_RS10920 2221850 2222239 - tail protein gene gene2172 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10920 UM146_RS10925 UM146_10570 UM146_RS10925 2222290 2222721 - tail protein gene gene2173 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10925 UM146_RS10930 UM146_10575 UM146_RS10930 2222735 2223487 - tail protein gene gene2174 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10930 UM146_RS10935 UM146_10580 UM146_RS10935 2223495 2223890 - tail protein gene gene2175 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10935 UM146_RS10940 UM146_10585 UM146_RS10940 2223887 2224420 - tail protein gene gene2176 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10940 UM146_RS10945 UM146_10590 UM146_RS10945 2224436 2224789 - tail attachment protein gene gene2177 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10945 UM146_RS10950 UM146_10595 UM146_RS10950 2224782 2225165 - hypothetical protein gene gene2178 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10950 UM146_RS10955 UM146_10600 UM146_RS10955 2225217 2226245 - head protein gene gene2179 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10955 UM146_RS10960 UM146_10605 UM146_RS10960 2226303 2226650 - Head decoration protein gene gene2180 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10960 UM146_RS10965 UM146_10610 UM146_RS10965 2226687 2228192 - scaffold protein gene gene2181 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10965 UM146_RS10970 UM146_10615 UM146_RS10970 2228182 2229774 - chromosome partitioning protein ParB gene gene2182 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10970 UM146_RS10975 UM146_10620 UM146_RS10975 2229771 2229977 - head-tail joining protein gene gene2183 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10975 UM146_RS10980 UM146_10625 UM146_RS10980 2229961 2231889 - terminase gene gene2184 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10980 UM146_RS10985 UM146_10630 UM146_RS10985 2231861 2232409 - terminase gene gene2185 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10985 UM146_RS10990 UM146_RS10990 UM146_RS10990 2232638 2232780 + hypothetical protein gene gene2186 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10990 UM146_RS10995 UM146_RS10995 UM146_RS10995 2232796 2233029 + hypothetical protein gene gene2187 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS10995 UM146_RS11000 UM146_10635 UM146_RS11000 2233087 2233497 + hypothetical protein gene gene2188 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11000 UM146_RS11005 UM146_10640 UM146_RS11005 2233805 2234269 - endopeptidase gene gene2189 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11005 UM146_RS11010 UM146_10650 UM146_RS11010 2234568 2235101 - lysozyme gene gene2190 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11010 UM146_RS11015 UM146_10655 UM146_RS11015 2235207 2235479 + hypothetical protein gene gene2191 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11015 UM146_RS11020 UM146_10660 UM146_RS11020 2235445 2235789 - hypothetical protein gene gene2192 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11020 UM146_RS11025 UM146_10665 UM146_RS11025 2235794 2236009 - holin gene gene2193 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11025 UM146_RS11030 UM146_10670 UM146_RS11030 2236278 2236505 - hypothetical protein gene gene2194 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11030 UM146_RS11035 UM146_t23883 UM146_RS11035 2237481 2237557 - tRNA-Arg tRNA gene2195 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11035 UM146_RS11040 UM146_t23885 UM146_RS11040 2237571 2237647 - tRNA-Arg tRNA gene2196 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11040 UM146_RS11045 UM146_t23887 UM146_RS11045 2237655 2237730 - tRNA-Met tRNA gene2197 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11045 UM146_RS11050 UM146_10675 UM146_RS11050 2237780 2238829 - DNA adenine methylase gene gene2198 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11050 UM146_RS11055 UM146_10680 UM146_RS11055 2238980 2239177 - hypothetical protein gene gene2199 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11055 UM146_RS11070 UM146_10690 UM146_RS11070 2240219 2240593 - endodeoxyribonuclease gene gene2201 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11070 UM146_RS11075 UM146_10695 UM146_RS11075 2240606 2241652 - hypothetical protein gene gene2202 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11075 UM146_RS11080 UM146_RS11080 UM146_RS11080 2241654 2241932 - hypothetical protein gene gene2203 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11080 UM146_RS11085 UM146_10700 UM146_RS11085 2242100 2242312 - hypothetical protein gene gene2204 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11085 UM146_RS11095 UM146_10705 UM146_RS11095 2242873 2243874 - hypothetical protein gene gene2205 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11095 UM146_RS11100 UM146_RS11100 UM146_RS11100 2243890 2244851 - hypothetical protein gene gene2206 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11100 UM146_RS11105 UM146_10720 UM146_RS11105 2245043 2245465 - hypothetical protein gene gene2207 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11105 UM146_RS11110 UM146_10725 UM146_RS11110 2245506 2246576 - hypothetical protein gene gene2208 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11110 UM146_RS11115 UM146_10730 UM146_RS11115 2246648 2247073 - Rha family transcriptional regulator gene gene2209 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11115 UM146_RS11120 UM146_10735 UM146_RS11120 2247057 2247299 - hypothetical protein gene gene2210 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11120 UM146_RS11125 UM146_10740 UM146_RS11125 2247391 2248029 + repressor gene gene2211 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11125 UM146_RS11130 UM146_RS11130 UM146_RS11130 2248322 2248477 + hypothetical protein gene gene2213 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11130 UM146_RS11135 UM146_10755 UM146_RS11135 2248637 2248858 + hypothetical protein gene gene2214 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11135 UM146_RS11140 UM146_RS11140 UM146_RS11140 2248859 2249153 - hypothetical protein gene gene2215 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11140 UM146_RS11145 UM146_10760 UM146_RS11145 2249424 2249612 + cell division inhibition protein DicB gene gene2216 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11145 UM146_RS11150 UM146_10765 UM146_RS11150 2249609 2249800 + hypothetical protein gene gene2217 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11150 UM146_RS11155 UM146_10770 UM146_RS11155 2249893 2252364 + exonuclease gene gene2218 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11155 UM146_RS11160 UM146_10775 UM146_RS11160 2252429 2252677 + excisionase gene gene2219 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11160 UM146_RS11165 UM146_RS11165 UM146_RS11165 2252655 2253784 + integrase gene gene2220 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11165 UM146_RS11170 UM146_10790 UM146_RS11170 2253830 2254468 - outer membrane protein W receptor for colicin S4 gene gene2221 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11170 UM146_RS11175 UM146_10795 UM146_RS11175 2254824 2255567 + hypothetical protein gene gene2222 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11175 UM146_RS11180 UM146_10800 UM146_RS11180 2255597 2256136 + intracellular septation protein A Involved in cell division%3B probably involved in intracellular septation gene gene2223 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11180 UM146_RS11185 UM146_10805 UM146_RS11185 2256242 2256640 + acyl-CoA thioester hydrolase YciA gene gene2224 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11185 UM146_RS11190 UM146_10810 UM146_RS11190 2256680 2257396 - transporter membrane spanning protein in TonB-ExbB-ExbD complex%3B transduces proton motive force of the cytoplasmic membrane to outer membrane transporters%3B involved in the transport of ron-siderophore complexes%2C vitamin B12 and colicins gene gene2225 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11190 UM146_RS11195 UM146_10815 UM146_RS11195 2257620 2257916 + hypothetical protein unknown function%3B YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase%2C but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity gene gene2226 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11195 UM146_RS11200 UM146_10820 UM146_RS11200 2258216 2259469 + voltage-gated potassium channel gene gene2227 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11200 UM146_RS11205 UM146_RS11205 UM146_RS11205 2259524 2259808 - hypothetical protein gene gene2228 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11205 UM146_RS11210 UM146_10825 cls cls 2259840 2261300 + cardiolipin synthase catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) gene gene2229 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11210 UM146_RS11215 UM146_10830 UM146_RS11215 2261335 2261664 + dsDNA-mimic protein highly acidic protein%3B the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi)%3B binds heat-unstable protein (HU-alpha) which is a histone-like protein gene gene2230 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11215 UM146_RS11220 UM146_10835 UM146_RS11220 2261717 2262721 - peptide ABC transporter ATP-binding protein with OppABCD is involved in the transport of oligopeptides%3B OppF and OppD are ATP-binding proteins gene gene2231 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11220 UM146_RS11225 UM146_10840 oppD oppD 2262718 2263731 - peptide ABC transporter ATP-binding protein gene gene2232 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11225 UM146_RS11230 UM146_10845 UM146_RS11230 2263743 2264651 - peptide ABC transporter permease with OppABDF is involved in the transport of oligopeptides of up to 5 amino acids into the cell gene gene2233 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11230 UM146_RS11235 UM146_10850 oppB oppB 2264666 2265586 - peptide ABC transporter permease gene gene2234 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11235 UM146_RS11240 UM146_10855 UM146_RS11240 2265672 2267303 - peptide ABC transporter substrate-binding protein is involved in the transport of the murein peptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate gene gene2235 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11240 UM146_RS11245 UM146_10865 UM146_RS11245 2268041 2268688 - membrane protein gene gene2236 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11245 UM146_RS11250 UM146_10870 UM146_RS11250 2269165 2271840 + acetaldehyde dehydrogenase gene gene2237 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11250 UM146_RS11255 UM146_RS11255 UM146_RS11255 2271966 2272481 + transposase gene gene2238 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11255 UM146_RS11260 UM146_10880 UM146_RS11260 2273298 2273915 - thymidine kinase catalyzes the formation of thymidine 5'-phosphate from thymidine gene gene2239 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11260 UM146_RS11265 UM146_10885 UM146_RS11265 2274519 2274932 + DNA-binding protein H-NS gene gene2240 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11265 UM146_RS11270 UM146_10890 UM146_RS11270 2275076 2275984 - UTP--glucose-1-phosphate uridylyltransferase together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase%2C an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate%3B regulates cellular levels of UDP-glucose gene gene2241 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11270 UM146_RS11275 UM146_10895 UM146_RS11275 2276186 2277199 - transcriptional regulator gene gene2242 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11275 UM146_RS11280 UM146_10900 UM146_RS11280 2277291 2278196 - hypothetical protein gene gene2243 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11280 UM146_RS11285 UM146_RS11285 UM146_RS11285 2278309 2278773 + hypothetical protein gene gene2244 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11285 UM146_RS11290 UM146_10910 UM146_RS11290 2278816 2279658 + formyltetrahydrofolate deformylase gene gene2245 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11290 UM146_RS11295 UM146_t23889 UM146_RS11295 2279818 2279902 + tRNA-Tyr tRNA gene2246 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11295 UM146_RS11300 UM146_t23891 UM146_RS11300 2279936 2280020 + tRNA-Tyr tRNA gene2247 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11300 UM146_RS11305 UM146_10915 UM146_RS11305 2280451 2281650 + transposase gene gene2248 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11305 UM146_RS11310 UM146_10920 narI narI 2281703 2282380 - respiratory nitrate reductase subunit gamma with NarGJH catalyzes the reduction of nitrate%3B the gamma subunit localizes NarGHI to the membrane%3B one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high gene gene2249 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11310 UM146_RS11315 UM146_10925 UM146_RS11315 2282380 2283090 - nitrate reductase molybdenum cofactor assembly chaperone NarJ delta subunit of nitrate reductase 1%3B chaperone for the insertion of the molybdenum cofactor and assembly of nitrate reductase 1 gene gene2250 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11315 UM146_RS11320 UM146_10930 narH narH 2283087 2284625 - nitrate reductase A subunit beta with NarGJI catalyzes the reduction of nitrate%3B the beta subunit is an iron sulfur cluster containing electron transfer subunit%3B one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high gene gene2251 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11320 UM146_RS11325 UM146_10935 narZ narZ 2284622 2288365 - nitrate reductase A subunit alpha with NarYV catalyzes the reduction of nitrate%3B the beta subunit is an iron sulfur cluster containing electron transfer subunit%3B one of 3 nitrate reductases in E. coli%3B expression of nitrate reductase Z is not dependent on nitrate levels gene gene2252 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11325 UM146_RS11330 UM146_10940 UM146_RS11330 2288758 2290149 - nitrate/nitrite transporter NarK involved in the transport of nitrate and nitrite gene gene2253 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11330 UM146_RS11335 UM146_RS11335 UM146_RS11335 2290244 2290462 - hypothetical protein gene gene2254 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11335 UM146_RS11340 UM146_10945 UM146_RS11340 2290488 2292284 + nitrate/nitrite two-component system sensor histidine kinase gene gene2255 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11340 UM146_RS11345 UM146_10950 UM146_RS11345 2292277 2292927 + transcriptional regulator two-component response regulator NarL%3B phosphorylated by NarQ%3B activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase gene gene2256 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11345 UM146_RS11350 UM146_10955 UM146_RS11350 2292928 2294322 - invasin gene gene2257 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11350 UM146_RS11355 UM146_10960 UM146_RS11355 2294507 2294860 + hypothetical protein gene gene2258 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11355 UM146_RS11360 UM146_10965 UM146_RS11360 2294904 2295599 - glutathione-specific gamma-glutamylcyclotransferase gene gene2259 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11360 UM146_RS11365 UM146_10970 chaB chaB 2295757 2295987 - cation transport regulator ChaB in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA%3B has weak affinity for calcium and magnesium ions gene gene2260 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11365 UM146_RS11370 UM146_10975 UM146_RS11370 2296257 2297357 + sodium:proton antiporter gene gene2261 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11370 UM146_RS11375 UM146_10980 UM146_RS11375 2297736 2297870 + hypothetical protein gene gene2262 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11375 UM146_RS11380 UM146_10985 UM146_RS11380 2298018 2298872 - 2-dehydro-3-deoxyphosphooctonate aldolase catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis gene gene2263 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11380 UM146_RS11385 UM146_10990 UM146_RS11385 2298908 2299717 - hypothetical protein gene gene2264 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11385 UM146_RS11390 UM146_10995 UM146_RS11390 2299721 2300113 - hypothetical protein gene gene2265 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11390 UM146_RS11395 UM146_11000 UM146_RS11395 2300110 2300943 - N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase HemK%3B PrmC%3B transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB gene gene2266 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11395 UM146_RS11400 UM146_11005 prfA prfA 2300943 2302025 - peptide chain release factor 1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1%3B this protein is similar to release factor 2 gene gene2267 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11400 UM146_RS11405 UM146_11010 hemA hemA 2302067 2303323 - glutamyl-tRNA reductase catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH%3B the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid%3B functions in porphyrin (tetrapyrroles) biosynthesis%3B the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins gene gene2268 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11405 UM146_RS11410 UM146_11015 lolB lolB 2303537 2304160 + outer membrane lipoprotein LolB Incorporates lipoproteins in the outer membrane after they are released by the LolA protein gene gene2269 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11410 UM146_RS11415 UM146_11020 UM146_RS11415 2304160 2305011 + 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase gene gene2270 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11415 UM146_RS11420 UM146_11025 UM146_RS11420 2305162 2306109 + ribose-phosphate pyrophosphokinase catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP gene gene2271 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11420 UM146_RS11425 UM146_11030 UM146_RS11425 2306261 2307913 + transporter role in sulfate transport across the inner membrane%3B member of the SulP family of sulfate transporters%3B seems to mediate transport via sulfate/proton symport gene gene2272 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11425 UM146_RS11430 UM146_11035 UM146_RS11430 2307968 2308246 - membrane protein YchH%3B transcription activated by CRP (cyclic AMP receptor protein)%2C a global transcription factor involved in regulation of metabolism in enteric bacteria%3B ychH presents a class II promoter to bind CRP%3B unknown function gene gene2273 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11430 UM146_RS11435 UM146_11040 UM146_RS11435 2308524 2309108 + peptidyl-tRNA hydrolase gene gene2274 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11435 UM146_RS11440 UM146_11045 ychF ychF 2309225 2310316 + GTP-binding protein EngD%3B translation-associated GTPase%3B the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3)%3B fluorescence spectroscopy revealed nucleic acid binding%3B the yeast protein YBR025c interacts with the translation elongation factor eEF1 gene gene2275 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11440 UM146_RS11445 UM146_11050 UM146_RS11445 2310452 2310682 + hypothetical protein gene gene2276 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11445 UM146_RS11450 UM146_11055 UM146_RS11450 2310720 2312639 - Fis family transcriptional regulator Positively regulates the dhaKLM operon from a sigma-70 promoter gene gene2277 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11450 UM146_RS11455 UM146_11060 UM146_RS11455 2312867 2313937 + dihydroxyacetone kinase subunit DhaK with DhaL and DhaM forms dihydroxyacetone kinase%2C which is responsible for phosphorylating dihydroxyacetone%3B DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase gene gene2278 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11455 UM146_RS11460 UM146_11065 UM146_RS11460 2313948 2314580 + dihydroxyacetone kinase subunit DhaL with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone gene gene2279 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11460 UM146_RS11465 UM146_11070 UM146_RS11465 2314591 2316009 + dihydroxyacetone kinase subunit DhaM phosphotransferaese subunit%3B phosphorylates dihydroxyacetone along with DhaK/DhaL gene gene2280 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11465 UM146_RS11470 UM146_11075 treA treA 2316328 2318025 + periplasmic trehalase periplasmic%3B catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell gene gene2281 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11470 UM146_RS11475 UM146_11080 UM146_RS11475 2318362 2319384 + ABC transporter ATP-binding protein gene gene2282 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11475 UM146_RS11480 UM146_11085 UM146_RS11480 2319384 2320364 + peptide ABC transporter substrate-binding protein gene gene2283 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11480 UM146_RS11485 UM146_11090 UM146_RS11485 2320361 2321119 + iron ABC transporter ATP-binding protein gene gene2284 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11485 UM146_RS11490 UM146_11095 UM146_RS11490 2321129 2321941 + methyltransferase gene gene2285 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11490 UM146_RS11495 UM146_11100 UM146_RS11495 2321938 2322792 + molybdenum transporter involved in molybdenum transport gene gene2286 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11495 UM146_RS11500 UM146_11105 UM146_RS11500 2322818 2324788 + TonB-dependent receptor gene gene2287 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11500 UM146_RS11505 UM146_11110 UM146_RS11505 2324838 2325092 - hypothetical protein gene gene2288 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11505 UM146_RS11510 UM146_11115 UM146_RS11510 2325293 2326027 + flagellar brake protein YcgR gene gene2289 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11510 UM146_RS11515 UM146_11120 emtA emtA 2326029 2326640 - murein transglycosylase catalyzes the cleavage of 1-4 beta-glycoside linkaged between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan gene gene2290 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11515 UM146_RS11520 UM146_11125 ldcA ldcA 2326740 2327654 + murein tetrapeptide carboxypeptidase catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine gene gene2291 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11520 UM146_RS11525 UM146_11130 cvrA cvrA 2327749 2329485 + K+/H+ antiporter NhaP2 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter%3B can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli gene gene2292 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11525 UM146_RS11530 UM146_11135 UM146_RS11530 2329542 2330612 - alanine racemase converts L-alanine to D-alanine which is used in cell wall biosynthesis%3B binds one pyridoxal phosphate per monomer%3B forms a homodimer gene gene2293 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11530 UM146_RS11535 UM146_11140 UM146_RS11535 2330622 2331920 - D-amino acid dehydrogenase catalyzes the oxidative deamination of D-amino acids gene gene2294 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11535 UM146_RS11540 UM146_11145 UM146_RS11540 2332250 2333782 + SpoVR family protein gene gene2295 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11540 UM146_RS11545 UM146_11150 UM146_RS11545 2333945 2334664 - fatty acid metabolism regulator protein Multifunctional regulator of fatty acid metabolism gene gene2296 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11545 UM146_RS11550 UM146_11155 nhaB nhaB 2334886 2336427 + Na+/H+ antiporter NhaB involved in regulation of intracellular pH under alkaline conditions gene gene2297 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11550 UM146_RS11555 UM146_11160 UM146_RS11555 2336573 2337103 + disulfide bond formation protein B disulfide oxidoreductase%3B integral membrane protein%3B required for perioplasmic disulfide bond formation%3B oxidizes DsbA protein gene gene2298 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11555 UM146_RS11560 UM146_11165 UM146_RS11560 2337148 2338416 - DNA polymerase V subunit UmuC binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC)%3B involved in translesion polymerization gene gene2299 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11560 UM146_RS11565 UM146_11170 UM146_RS11565 2338416 2338835 - DNA polymerase V subunit UmuD binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC)%3B involved in translesion polymerization gene gene2300 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11565 UM146_RS11570 UM146_RS11570 UM146_RS11570 2339140 2339422 + hemolysin activation protein HecB gene gene2301 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11570 UM146_RS11575 UM146_11180 UM146_RS11575 2339629 2340075 - hypothetical protein gene gene2302 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11575 UM146_RS11580 UM146_11185 UM146_RS11580 2340167 2340826 - hypothetical protein gene gene2303 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11580 UM146_RS11585 UM146_11190 UM146_RS11585 2340898 2341224 - hypothetical protein gene gene2304 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11585 UM146_RS11590 UM146_11195 UM146_RS11590 2341433 2341834 + hypothetical protein gene gene2305 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11590 UM146_RS11595 UM146_11200 UM146_RS11595 2341954 2342322 - hypothetical protein gene gene2306 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11595 UM146_RS11600 UM146_11205 minC minC 2342842 2343537 + septum site-determining protein MinC blocks the formation of polar Z-ring septums gene gene2307 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11600 UM146_RS11605 UM146_11210 UM146_RS11605 2343561 2344373 + septum site-determining protein MinD ATPase%3B with MinC inhibits cell division by blocking formation of the polar Z ring septums gene gene2308 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11605 UM146_RS11610 UM146_11215 minE minE 2344377 2344643 + cell division topological specificity factor works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell gene gene2309 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11610 UM146_RS11615 UM146_11220 UM146_RS11615 2345015 2345341 - ATPase gene gene2310 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11615 UM146_RS11620 UM146_RS11620 UM146_RS11620 2345759 2345931 + hypothetical protein gene gene2311 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11620 UM146_RS11625 UM146_11225 UM146_RS11625 2345992 2346276 + hypothetical protein gene gene2312 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11625 UM146_RS11630 UM146_11230 UM146_RS11630 2346286 2346615 + hypothetical protein gene gene2313 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11630 UM146_RS11635 UM146_11235 UM146_RS11635 2346673 2347200 - hypothetical protein gene gene2314 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11635 UM146_RS11640 UM146_RS11640 UM146_RS11640 2347346 2347723 - ATPase gene gene2315 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11640 UM146_RS11645 UM146_11245 UM146_RS11645 2348013 2348192 - ATPase gene gene2316 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11645 UM146_RS11655 UM146_11250 UM146_RS11655 2348590 2348808 - membrane protein gene gene2317 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11655 UM146_RS11660 UM146_11260 UM146_RS11660 2349133 2349636 + transposase gene gene2318 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11660 UM146_RS11665 UM146_11265 UM146_RS11665 2349674 2349946 - two-component-system connector protein YmgA gene gene2319 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11665 UM146_RS11670 UM146_11270 UM146_RS11670 2349989 2350225 - two-component-system connector protein YcgZ gene gene2320 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11670 UM146_RS11675 UM146_11275 UM146_RS11675 2350539 2351750 + diguanylate phosphodiesterase gene gene2321 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11675 UM146_RS11680 UM146_11280 UM146_RS11680 2351955 2352686 + MerR family transcriptional regulator gene gene2322 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11680 UM146_RS11685 UM146_11285 UM146_RS11685 2352907 2353311 + hypothetical protein gene gene2323 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11685 UM146_RS11690 UM146_RS11690 UM146_RS11690 2353364 2353489 + hypothetical protein gene gene2324 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11690 UM146_RS11695 UM146_11295 UM146_RS11695 2353919 2354071 - hypothetical protein gene gene2325 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11695 UM146_RS11700 UM146_11300 UM146_RS11700 2354197 2354955 - hypothetical protein gene gene2326 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11700 UM146_RS11705 UM146_RS11705 UM146_RS11705 2355091 2355375 - hypothetical protein gene gene2327 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11705 UM146_RS11710 UM146_11305 UM146_RS11710 2355654 2356568 + iron ABC transporter substrate-binding protein gene gene2328 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11710 UM146_RS11715 UM146_11310 UM146_RS11715 2356568 2357395 + manganese transporter with SitACD is involved in the transport of manganese and iron gene gene2329 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11715 UM146_RS11720 UM146_11315 UM146_RS11720 2357392 2358249 + membrane protein gene gene2330 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11720 UM146_RS11725 UM146_11320 UM146_RS11725 2358246 2359103 + membrane protein gene gene2331 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11725 UM146_RS11730 UM146_11325 UM146_RS11730 2359195 2359488 - hypothetical protein gene gene2332 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11730 UM146_RS11735 UM146_11330 UM146_RS11735 2359501 2359779 - hypothetical protein gene gene2333 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11735 UM146_RS11740 UM146_RS11740 UM146_RS11740 2359776 2361500 - phage tail protein gene gene2334 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11740 UM146_RS11750 UM146_RS11750 UM146_RS11750 2361727 2361891 + hypothetical protein gene gene2335 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11750 UM146_RS11755 UM146_11340 UM146_RS11755 2361895 2365377 - host specificity protein J gene gene2336 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11755 UM146_RS11760 UM146_11345 UM146_RS11760 2365438 2366010 - tail assembly protein gene gene2337 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11760 UM146_RS11765 UM146_11350 UM146_RS11765 2366007 2366750 - endopeptidase gene gene2338 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11765 UM146_RS11770 UM146_11355 UM146_RS11770 2366756 2367454 - tail protein gene gene2339 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11770 UM146_RS11775 UM146_11360 UM146_RS11775 2367454 2367783 - tail protein gene gene2340 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11775 UM146_RS11780 UM146_11365 UM146_RS11780 2367780 2370341 - tail protein gene gene2341 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11780 UM146_RS11785 UM146_11370 UM146_RS11785 2370334 2370723 - phage tail protein gene gene2342 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11785 UM146_RS11790 UM146_11375 UM146_RS11790 2370750 2371172 - tail protein gene gene2343 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11790 UM146_RS11795 UM146_11380 UM146_RS11795 2371188 2371928 - tail protein gene gene2344 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11795 UM146_RS11800 UM146_11385 UM146_RS11800 2371936 2372331 - tail protein gene gene2345 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11800 UM146_RS11805 UM146_11390 UM146_RS11805 2372328 2372906 - tail protein gene gene2346 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11805 UM146_RS11810 UM146_11395 UM146_RS11810 2372918 2373271 - tail attachment protein gene gene2347 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11810 UM146_RS11815 UM146_11400 UM146_RS11815 2373264 2373638 - hypothetical protein gene gene2348 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11815 UM146_RS11820 UM146_11405 UM146_RS11820 2373690 2374718 - phage head protein gene gene2349 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11820 UM146_RS11825 UM146_11410 UM146_RS11825 2374776 2375123 - Head decoration protein gene gene2350 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11825 UM146_RS11830 UM146_11415 UM146_RS11830 2375160 2376665 - scaffold protein gene gene2351 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11830 UM146_RS11835 UM146_11420 UM146_RS11835 2376655 2378247 - chromosome partitioning protein ParB gene gene2352 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11835 UM146_RS11840 UM146_11425 UM146_RS11840 2378244 2378450 - phage head-stabilizing protein gene gene2353 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11840 UM146_RS11845 UM146_11430 UM146_RS11845 2378434 2380362 - terminase gene gene2354 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11845 UM146_RS11850 UM146_11435 UM146_RS11850 2380334 2380882 - phage terminase small subunit gene gene2355 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11850 UM146_RS11855 UM146_RS11855 UM146_RS11855 2380964 2381134 - DNA-packaging protein gene gene2356 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11855 UM146_RS11860 UM146_RS11860 UM146_RS11860 2381150 2381470 + hypothetical protein gene gene2357 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11860 UM146_RS11865 UM146_RS11865 UM146_RS11865 2381358 2381711 + hypothetical protein gene gene2358 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11865 UM146_RS11870 UM146_11445 UM146_RS11870 2381834 2382160 - cell envelope biogenesis protein TonB gene gene2359 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11870 UM146_RS11875 UM146_RS11875 UM146_RS11875 2382360 2382473 + hypothetical protein gene gene2360 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11875 UM146_RS11880 UM146_11450 UM146_RS11880 2382641 2382934 + hypothetical protein gene gene2361 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11880 UM146_RS11885 UM146_11455 UM146_RS11885 2382966 2383427 - endopeptidase gene gene2362 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11885 UM146_RS11890 UM146_11460 UM146_RS11890 2383424 2383921 - lysozyme gene gene2363 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11890 UM146_RS11895 UM146_11465 UM146_RS11895 2383921 2384136 - Lysis protein S homolog from lambdoid prophage DLP12 gene gene2364 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11895 UM146_RS11900 UM146_11470 UM146_RS11900 2384725 2385807 + porin gene gene2365 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11900 UM146_RS11905 UM146_11475 UM146_RS11905 2385996 2386379 - antitermination protein gene gene2366 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11905 UM146_RS11910 UM146_11480 UM146_RS11910 2386465 2386605 - hypothetical protein gene gene2367 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11910 UM146_RS11915 UM146_11485 UM146_RS11915 2386602 2386964 - crossover junction endodeoxyribonuclease RusA gene gene2368 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11915 UM146_RS11920 UM146_11490 UM146_RS11920 2386984 2387178 - protein ninF gene gene2369 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11920 UM146_RS11925 UM146_11495 UM146_RS11925 2387171 2387512 - protein ninX gene gene2370 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11925 UM146_RS11930 UM146_11500 UM146_RS11930 2387515 2387691 - protein ninE gene gene2371 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11930 UM146_RS11935 UM146_11505 UM146_RS11935 2387688 2388215 - DNA methylase gene gene2372 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11935 UM146_RS11940 UM146_11510 UM146_RS11940 2388212 2388652 - phage protein NinB gene gene2373 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11940 UM146_RS11945 UM146_11515 UM146_RS11945 2388726 2389016 - protein ren gene gene2374 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11945 UM146_RS11950 UM146_11520 UM146_RS11950 2389013 2389714 - Replication protein 14 gene gene2375 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11950 UM146_RS11955 UM146_RS11955 UM146_RS11955 2389711 2390609 - Replication protein O gene gene2376 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11955 UM146_RS11960 UM146_11535 UM146_RS11960 2390642 2390938 - hypothetical protein gene gene2377 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11960 UM146_RS11965 UM146_RS11965 UM146_RS11965 2391080 2391295 - Cro family transcriptional regulator gene gene2378 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11965 UM146_RS11970 UM146_11545 UM146_RS11970 2391413 2392066 + repressor gene gene2379 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11970 UM146_RS11975 UM146_11550 UM146_RS11975 2392106 2392663 + hypothetical protein gene gene2380 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11975 UM146_RS11980 UM146_11555 UM146_RS11980 2392660 2393412 + hypothetical protein gene gene2381 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11980 UM146_RS11990 UM146_11560 UM146_RS11990 2393689 2393871 + hypothetical protein gene gene2382 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11990 UM146_RS11995 UM146_RS11995 UM146_RS11995 2393849 2394121 + antitermination protein N gene gene2383 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS11995 UM146_RS12000 UM146_11565 UM146_RS12000 2394138 2394719 - superinfection exclusion protein B gene gene2384 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12000 UM146_RS12005 UM146_11570 UM146_RS12005 2394933 2395133 + Restriction inhibitor protein ral gene gene2385 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12005 UM146_RS12010 UM146_11575 UM146_RS12010 2395316 2395684 + lambda prophage-derived protein ea10 gene gene2386 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12010 UM146_RS12015 UM146_11580 UM146_RS12015 2395757 2395921 + hypothetical protein gene gene2387 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12015 UM146_RS12020 UM146_RS12020 UM146_RS12020 2395890 2396033 + hypothetical protein gene gene2388 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12020 UM146_RS12025 UM146_11590 UM146_RS12025 2396109 2396405 + host-nuclease inhibitor protein Gam gene gene2389 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12025 UM146_RS12030 UM146_11595 UM146_RS12030 2396411 2397196 + recombinase gene gene2390 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12030 UM146_RS12035 UM146_11600 UM146_RS12035 2397193 2397873 + exonuclease gene gene2391 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12035 UM146_RS12040 UM146_11605 UM146_RS12040 2397870 2398052 + hypothetical protein gene gene2392 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12040 UM146_RS12045 UM146_11610 UM146_RS12045 2398025 2398216 + hypothetical protein gene gene2393 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12045 UM146_RS12050 UM146_RS12050 UM146_RS12050 2398213 2398296 + hypothetical protein gene gene2394 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12050 UM146_RS12055 UM146_RS12055 UM146_RS12055 2398293 2398504 + hypothetical protein gene gene2395 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12055 UM146_RS12060 UM146_11615 UM146_RS12060 2398603 2398824 + conjugal transfer protein TraR gene gene2396 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12060 UM146_RS12065 UM146_11620 UM146_RS12065 2398824 2399150 + RNA-binding protein gene gene2397 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12065 UM146_RS12070 UM146_RS12070 UM146_RS12070 2399134 2399370 + hypothetical protein gene gene2398 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12070 UM146_RS12075 UM146_RS12075 UM146_RS12075 2399514 2399750 + excisionase gene gene2399 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12075 UM146_RS12080 UM146_11630 UM146_RS12080 2399740 2400882 + integrase gene gene2400 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12080 UM146_RS12085 UM146_11635 UM146_RS12085 2400995 2402245 - isocitrate dehydrogenase Converts isocitrate to alpha ketoglutarate gene gene2401 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12085 UM146_RS12090 UM146_11640 UM146_RS12090 2402417 2403070 + ribosomal large subunit pseudouridine synthase E catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA gene gene2402 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12090 UM146_RS12095 UM146_11645 UM146_RS12095 2403080 2403541 + phosphatase gene gene2403 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12095 UM146_RS12100 UM146_11650 mnmA mnmA 2403595 2404701 + tRNA-specific 2-thiouridylase MnmA catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs gene gene2404 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12100 UM146_RS12105 UM146_11655 UM146_RS12105 2404737 2405378 + high frequency lysogenization protein HflD HflD%3B UPF0274%3B in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein%3B in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis gene gene2405 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12105 UM146_RS12110 UM146_11660 UM146_RS12110 2405382 2406752 + adenylosuccinate lyase Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide gene gene2406 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12110 UM146_RS12115 UM146_11665 UM146_RS12115 2406921 2407592 + two-component system response regulator response regulator in two-component regulatory system with PhoQ%3B involved in magnesium starvation and stress gene gene2407 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12115 UM146_RS12120 UM146_11670 UM146_RS12120 2407592 2409052 + sensor protein PhoQ gene gene2408 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12120 UM146_RS12125 UM146_11675 UM146_RS12125 2409128 2410249 + 50S ribosomal protein L16 arginine hydroxylase gene gene2409 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12125 UM146_RS12130 UM146_RS12130 UM146_RS12130 2410298 2411523 - peptidase T gene gene2410 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12130 UM146_RS12135 UM146_RS12135 UM146_RS12135 2411579 2411794 + hypothetical protein gene gene2411 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12135 UM146_RS12140 UM146_11690 potA potA 2411773 2412909 + Fe3+/spermidine/putrescine ABC transporter ATP-binding protein functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport%3B PotA is the membrane-associated ATPase gene gene2412 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12140 UM146_RS12145 UM146_11695 potB potB 2412893 2413750 + spermidine/putrescine ABC transporter permease can transport spermidine and putrescine but affinity is higher for spermidine%3B forms a complex of PotA2BCD%3B PotB is a membrane component gene gene2413 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12145 UM146_RS12150 UM146_11700 potC potC 2413747 2414541 + spermidine/putrescine ABC transporter permease can transport spermidine and putrescine but affinity is higher for spermidine%3B forms a complex of PotA2BCD%3B PotC is a membrane component gene gene2414 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12150 UM146_RS12155 UM146_11705 potD potD 2414538 2415584 + spermidine/putrescine ABC transporter substrate-binding protein can transport spermidine and putrescine but affinity is higher for spermidine%3B forms a complex of PotA2BCD%3B PotD is a periplasmic component that binds the substrate gene gene2415 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12155 UM146_RS12160 UM146_11710 UM146_RS12160 2415642 2416102 + hypothetical protein gene gene2416 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12160 UM146_RS12165 UM146_11715 UM146_RS12165 2416099 2416887 + membrane protein gene gene2417 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12165 UM146_RS12170 UM146_11720 UM146_RS12170 2417025 2417846 - NAD-dependent deacetylase Modulates the activities of several enzymes which are inactive in their acetylated form gene gene2418 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12170 UM146_RS12175 UM146_11725 UM146_RS12175 2417862 2418773 - N-acetyl-D-glucosamine kinase catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine gene gene2419 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12175 UM146_RS12180 UM146_11730 UM146_RS12180 2418802 2420046 - transporter part of the ATP-dependent transport system LolCDE%3B responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane gene gene2420 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12180 UM146_RS12185 UM146_11735 lolD lolD 2420046 2420747 - lipoprotein-releasing system ATP-binding protein LolD outer membrane specific%3B part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone gene gene2421 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12185 UM146_RS12190 UM146_11740 UM146_RS12190 2420740 2421939 - lipoprotein-releasing system protein LolC part of the ATP-dependent transport system LolCDE%3B responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane gene gene2422 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12190 UM146_RS12195 UM146_11745 UM146_RS12195 2422201 2423276 + hypothetical protein gene gene2423 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12195 UM146_RS12200 UM146_11750 UM146_RS12200 2423404 2426850 + transcription-repair coupling factor gene gene2424 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12200 UM146_RS12205 UM146_11755 UM146_RS12205 2426998 2427957 + peptidoglycan-binding protein LysM gene gene2425 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12205 UM146_RS12210 UM146_11760 UM146_RS12210 2428038 2428295 - multiple stress resistance protein BhsA gene gene2426 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12210 UM146_RS12215 UM146_11765 UM146_RS12215 2428536 2429168 + TetR family transcriptional regulator gene gene2427 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12215 UM146_RS12220 UM146_11770 UM146_RS12220 2429230 2429769 - hypothetical protein gene gene2428 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12220 UM146_RS12225 UM146_11780 UM146_RS12225 2429996 2431300 - NADH dehydrogenase gene gene2429 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12225 UM146_RS12230 UM146_11785 UM146_RS12230 2431699 2432241 - hypothetical protein gene gene2430 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12230 UM146_RS12235 UM146_11790 UM146_RS12235 2432264 2433289 - beta-hexosaminidase hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides gene gene2431 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12235 UM146_RS12240 UM146_11795 thiK thiK 2433300 2434124 - thiamine kinase catalyzes the phosphorylation of thiamine to thiamine phosphate gene gene2432 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12240 UM146_RS12245 UM146_11800 UM146_RS12245 2434105 2434746 - penicillin-binding protein activator LpoB gene gene2433 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12245 UM146_RS12250 UM146_11805 UM146_RS12250 2434760 2435137 - membrane protein gene gene2434 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12250 UM146_RS12255 UM146_11810 UM146_RS12255 2435140 2435499 - purine nucleoside phosphoramidase gene gene2435 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12255 UM146_RS12260 UM146_11815 UM146_RS12260 2435833 2438022 + ferric-rhodotorulic acid outer membrane transporter gene gene2436 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12260 UM146_RS12265 UM146_11820 UM146_RS12265 2438082 2439515 - PTS glucose EIICB component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene2437 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12265 UM146_RS12270 UM146_11825 UM146_RS12270 2439810 2440607 - DNAse gene gene2438 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12270 UM146_RS12275 UM146_11830 UM146_RS12275 2440618 2441622 - DNA polymerase III subunit delta' catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand%3B the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA gene gene2439 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12275 UM146_RS12280 UM146_11835 UM146_RS12280 2441619 2442260 - thymidylate kinase gene gene2440 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12280 UM146_RS12285 UM146_11840 UM146_RS12285 2442250 2443272 - aminodeoxychorismate lyase gene gene2441 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12285 UM146_RS12290 UM146_11845 UM146_RS12290 2443275 2444084 - 4-amino-4-deoxychorismate lyase catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate gene gene2442 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12290 UM146_RS12295 UM146_11850 UM146_RS12295 2444204 2445445 - 3-oxoacyl-ACP synthase II FabF%3B beta-ketoacyl-ACP synthase II%2C KASII%3B catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP%3B required for the elongation of short-chain unsaturated acyl-ACP gene gene2443 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12295 UM146_RS12300 UM146_11855 UM146_RS12300 2445532 2445768 - acyl carrier protein carries the fatty acid chain in fatty acid biosynthesis gene gene2444 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12300 UM146_RS12305 UM146_11860 fabG fabG 2445979 2446713 - 3-oxoacyl-ACP reductase catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis gene gene2445 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12305 UM146_RS12310 UM146_11865 UM146_RS12310 2446726 2447655 - malonyl CoA-ACP transacylase gene gene2446 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12310 UM146_RS12315 UM146_11870 UM146_RS12315 2447671 2448624 - 3-oxoacyl-ACP synthase III FabH%3B beta-ketoacyl-acyl carrier protein synthase III%3B catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation%3B differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs gene gene2447 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12315 UM146_RS12320 UM146_11875 UM146_RS12320 2448692 2449732 - phosphate acyltransferase gene gene2448 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12320 UM146_RS12325 UM146_11880 rpmF rpmF 2449843 2450016 - 50S ribosomal protein L32 some L32 proteins have zinc finger motifs consisting of CXXC while others do not gene gene2449 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12325 UM146_RS12330 UM146_11885 UM146_RS12330 2450068 2450589 - DUF177 domain-containing protein gene gene2450 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12330 UM146_RS12335 UM146_11890 UM146_RS12335 2450788 2451372 + m(7)GTP pyrophosphatase Maf%3B overexpression in Bacillus subtilis inhibits septation in the dividing cell gene gene2451 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12335 UM146_RS12340 UM146_11895 UM146_RS12340 2451484 2452443 - ribosomal large subunit pseudouridine synthase C catalyzes the transformation of uracil to pseudouracil at nucleotides U955%2C U2504%2C and U2580 in 23S rRNA gene gene2452 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12340 UM146_RS12345 UM146_11900 UM146_RS12345 2452561 2452881 - hypothetical protein gene gene2453 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12345 UM146_RS12350 UM146_11905 rne rne 2453016 2456201 + ribonuclease E bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein%3B forms part of the membrane-associated degradosome complex along with PNPase%2C RhlB%2C and enolase gene gene2454 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12350 UM146_RS12355 UM146_11910 flgL flgL 2456396 2457349 - flagellar hook-associated protein FlgL with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook%3B Yersinia%2C Vibrio parahaemolyticus%2C Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes gene gene2455 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12355 UM146_RS12360 UM146_11915 flgK flgK 2457361 2459004 - flagellar hook protein FlgK with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook gene gene2456 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12360 UM146_RS12365 UM146_11920 flgJ flgJ 2459070 2460011 - flagellar rod assembly protein FlgJ Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space gene gene2457 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12365 UM146_RS12370 UM146_11925 flgI flgI 2460011 2461108 - flagellar P-ring protein part of the basal body which consists of four rings L%2C P%2C S%2C and M mounted on a central rod%3B Vibrio parahaemolyticus%2C Yersinia%2C Bradyrhizobium and other bacteria have two copies of this and other flagellar genes%3B the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum gene gene2458 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12370 UM146_RS12375 UM146_11930 flgH flgH 2461120 2461818 - flagellar L-ring protein part of the flagellar basal body which consists of four rings L%2CP%2C S and M mounted on a central rod gene gene2459 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12375 UM146_RS12380 UM146_11935 flgG flgG 2461871 2462653 - flagellar basal body rod protein FlgG makes up the distal portion of the flagellar basal body rod gene gene2460 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12380 UM146_RS12385 UM146_11940 flgF flgF 2462825 2463580 - flagellar basal-body rod protein FlgF FlgF%2C with FlgB and C%2C makes up the proximal portion of the flagellar basal body rod gene gene2461 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12385 UM146_RS12390 UM146_11945 flgE flgE 2463600 2464805 - flagellar hook protein FlgE the hook connects flagellar basal body to the flagellar filament gene gene2462 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12390 UM146_RS12395 UM146_11950 flgD flgD 2464830 2465525 - flagellar basal body rod modification protein acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod%3B Yersinia%2C Vibrio parahaemolyticus%2C Bradyrhizobium and other organisms have 2 copies of some flagellar genes%3B in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production gene gene2463 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12395 UM146_RS12400 UM146_11955 flgC flgC 2465537 2465941 - flagellar basal-body rod protein FlgC with FlgF and B makes up the proximal portion of the flagellar basal body rod gene gene2464 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12400 UM146_RS12405 UM146_11960 flgB flgB 2465945 2466361 - flagellar biosynthesis protein FlgB with FlgF and C makes up the proximal portion of the flagellar basal body rod%3B Vibrio parahaemolyticus protein is associated with the polar flagella gene gene2465 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12405 UM146_RS12410 UM146_11965 flgA flgA 2466516 2467175 + flagellar basal body P-ring biosynthesis protein FlgA required for the assembly of the flagellar basal body P-ring gene gene2466 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12410 UM146_RS12415 UM146_11970 UM146_RS12415 2467251 2467544 + negative regulator of flagellin synthesis regulates the flagellar specific sigma28 transcription factor gene gene2467 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12415 UM146_RS12420 UM146_11975 UM146_RS12420 2467549 2467965 + flagella synthesis chaperone protein FlgN export chaperone for FlgK and FlgL gene gene2468 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12420 UM146_RS12425 UM146_11980 UM146_RS12425 2468005 2469540 - lipid II flippase MurJ gene gene2469 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12425 UM146_RS12430 UM146_11990 UM146_RS12430 2469650 2470573 - virulence factor MviM gene gene2470 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12430 UM146_RS12435 UM146_11995 UM146_RS12435 2470575 2471222 - hypothetical protein gene gene2471 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12435 UM146_RS12440 UM146_12000 UM146_RS12440 2471233 2471817 - alanine acetyltransferase gene gene2472 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12440 UM146_RS12445 UM146_12005 UM146_RS12445 2472053 2473261 + multidrug resistance protein MdtH Confers resistance to norfloxacin and enoxacin gene gene2473 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12445 UM146_RS12450 UM146_12010 UM146_RS12450 2473325 2473972 + glutaredoxin cofactor involved in the reduction of disulfides gene gene2474 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12450 UM146_RS12455 UM146_12015 UM146_RS12455 2474106 2474666 + lipoprotein gene gene2475 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12455 UM146_RS12460 UM146_12020 UM146_RS12460 2474772 2475818 + dihydroorotase gene gene2476 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12460 UM146_RS12465 UM146_12025 UM146_RS12465 2475892 2476137 + DNA-damage-inducible protein I gene gene2477 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12465 UM146_RS12470 UM146_12030 bssS bssS 2476427 2476681 + biofilm regulator BssS BssS%3B regulator of biofilm through signal secretion%3B disruption of this gene in Escherichia coli led to effects on biofilm formation%2C alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing gene gene2478 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12470 UM146_RS12475 UM146_12035 solA solA 2476796 2477914 + N-methyl-L-tryptophan oxidase catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde%3B FAD-binding%3B can also catalyze the demethylation of other N-methyl amino acids gene gene2479 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12475 UM146_RS12480 UM146_12040 UM146_RS12480 2477962 2478075 + hypothetical protein gene gene2480 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12480 UM146_RS12485 UM146_12045 UM146_RS12485 2478336 2478902 + cytochrome B561 gene gene2481 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12485 UM146_RS12490 UM146_12050 UM146_RS12490 2478906 2479481 + hypothetical protein gene gene2482 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12490 UM146_RS12495 UM146_12055 UM146_RS12495 2479523 2480575 - sulfurtransferase gene gene2483 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12495 UM146_RS12500 UM146_12060 UM146_RS12500 2480800 2481720 + lipid A biosynthesis lauroyl acyltransferase Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA gene gene2484 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12500 UM146_RS12505 UM146_12065 UM146_RS12505 2481892 2483118 + multidrug resistance protein MdtG Confers resistance to fosfomycin and deoxycholate gene gene2485 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12505 UM146_RS12510 UM146_RS12510 UM146_RS12510 2483073 2483171 + hypothetical protein gene gene2486 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12510 UM146_RS12515 UM146_12070 UM146_RS12515 2483201 2483575 + SecY/SecA suppressor protein gene gene2487 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12515 UM146_RS12520 UM146_12075 UM146_RS12520 2483576 2483803 - lipoprotein gene gene2488 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12520 UM146_RS12525 UM146_12080 UM146_RS12525 2483975 2486488 - glucosyltransferase necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space gene gene2489 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12525 UM146_RS12530 UM146_12085 mdoG mdoG 2486511 2488064 - glucan biosynthesis protein G involved in the biosynthesis of osmoregulated periplasmic glucans%3B required for the assembly of the polyglucose structure of glucan gene gene2490 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12530 UM146_RS12535 UM146_RS12535 UM146_RS12535 2488117 2488248 + hypothetical protein gene gene2491 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12535 UM146_RS12540 UM146_RS12540 UM146_RS12540 2488252 2488395 + hypothetical protein gene gene2492 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12540 UM146_RS12545 UM146_12090 opgC opgC 2488440 2489597 + glucan biosynthesis protein C required for the transfer of succinyl residues to osmoregulated periplasmic glucans gene gene2493 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12545 UM146_RS12550 UM146_12095 UM146_RS12550 2489605 2491026 - cardiolipin synthase C gene gene2494 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12550 UM146_RS12555 UM146_12100 UM146_RS12555 2491028 2491561 - O-acetyl-ADP-ribose deacetylase interacts and inactivates RNase III during cold shock gene gene2495 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12555 UM146_RS12560 UM146_12105 UM146_RS12560 2491656 2491967 - hypothetical protein gene gene2496 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12560 UM146_RS12565 UM146_12110 csgC csgC 2492088 2492420 - curli assembly protein CsgC involved in autoagglutination of curliated cells%3B not involved in production of curli fibers gene gene2497 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12565 UM146_RS12570 UM146_12115 csgA csgA 2492478 2492933 - major curlin subunit the major structural subunit of curlin which assemble to form curli which can bind to fibronectin gene gene2498 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12570 UM146_RS12575 UM146_12120 csgB csgB 2492974 2493429 - curlin CsgB%3B functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface gene gene2499 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12575 UM146_RS12580 UM146_RS12580 UM146_RS12580 2493532 2493770 + hypothetical protein gene gene2500 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12580 UM146_RS12585 UM146_12125 UM146_RS12585 2494182 2494832 + transcriptional regulator activates the csgBA and csgDEFG operons involved in biofilm formation gene gene2501 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12585 UM146_RS12590 UM146_12130 UM146_RS12590 2494837 2495226 + curli production assembly/transport component CsgE chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation)%3B part of the curli secretion and assembly protein complex gene gene2502 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12590 UM146_RS12595 UM146_12135 UM146_RS12595 2495251 2495667 + curli production assembly/transport component CsgF nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation)%3B part of the curli secretion and assembly protein complex gene gene2503 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12595 UM146_RS12600 UM146_12140 UM146_RS12600 2495694 2496527 + curli production assembly/transport component CsgG involved in the stability of the curlin proteins during assembly%3B involved in the secretion of the major curlin subunit CsgA across the outer membrane gene gene2504 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12600 UM146_RS12605 UM146_12145 UM146_RS12605 2496592 2497083 - membrane protein gene gene2505 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12605 UM146_RS12610 UM146_12150 UM146_RS12610 2497185 2497739 - molecular chaperone gene gene2506 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12610 UM146_RS12615 UM146_12155 UM146_RS12615 2497763 2498500 - phosphatase gene gene2507 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12615 UM146_RS12620 UM146_12160 ghrA ghrA 2498555 2499493 - glyoxylate/hydroxypyruvate reductase A catalyzes the formation of glycolate and glycerate from glyoxylate and hydroxypyruvate%2C respectively gene gene2508 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12620 UM146_RS12625 UM146_t23893 UM146_RS12625 2499727 2499814 + tRNA-Ser tRNA gene2509 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12625 UM146_RS12630 UM146_12165 UM146_RS12630 2499964 2500806 - restriction methylase gene gene2510 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12630 UM146_RS12635 UM146_12170 UM146_RS12635 2500899 2501096 - hypothetical protein gene gene2511 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12635 UM146_RS12640 UM146_12175 UM146_RS12640 2501108 2501596 - hypothetical protein gene gene2512 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12640 UM146_RS12645 UM146_12180 UM146_RS12645 2501596 2501970 - toxin gene gene2513 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12645 UM146_RS12650 UM146_12185 UM146_RS12650 2502017 2502394 - antitoxin gene gene2514 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12650 UM146_RS12655 UM146_12190 UM146_RS12655 2502444 2503088 - hypothetical protein gene gene2515 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12655 UM146_RS12660 UM146_12195 UM146_RS12660 2503107 2503328 - hypothetical protein gene gene2516 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12660 UM146_RS12665 UM146_12200 UM146_RS12665 2503391 2503867 - hypothetical protein gene gene2517 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12665 UM146_RS12670 UM146_12205 UM146_RS12670 2503883 2504356 - hypothetical protein gene gene2518 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12670 UM146_RS12675 UM146_12210 UM146_RS12675 2504450 2504695 - hypothetical protein gene gene2519 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12675 UM146_RS12680 UM146_12215 UM146_RS12680 2504695 2505516 - hypothetical protein gene gene2520 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12680 UM146_RS12685 UM146_12220 UM146_RS12685 2505847 2508693 - hypothetical protein gene gene2521 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12685 UM146_RS12690 UM146_12225 UM146_RS12690 2509066 2509938 - hypothetical protein gene gene2522 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12690 UM146_RS12695 UM146_12230 UM146_RS12695 2510292 2510534 + hypothetical protein gene gene2523 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12695 UM146_RS12700 UM146_12235 UM146_RS12700 2510825 2511058 + hypothetical protein gene gene2524 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12700 UM146_RS12705 UM146_RS12705 UM146_RS12705 2512131 2512214 + hypothetical protein gene gene2525 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12705 UM146_RS12710 UM146_12245 UM146_RS12710 2513024 2513449 - hypothetical protein gene gene2526 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12710 UM146_RS12715 UM146_12250 UM146_RS12715 2513485 2514621 - hypothetical protein gene gene2527 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12715 UM146_RS12720 UM146_12255 UM146_RS12720 2515282 2515464 + transposase gene gene2528 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12720 UM146_RS12725 UM146_12260 UM146_RS12725 2515571 2516770 - hypothetical protein gene gene2529 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12725 UM146_RS12730 UM146_12265 UM146_RS12730 2517034 2517825 - ABC transporter gene gene2530 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12730 UM146_RS12735 UM146_12270 UM146_RS12735 2517844 2519814 - ligand-gated channel gene gene2531 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12735 UM146_RS12740 UM146_RS12740 UM146_RS12740 2520160 2521523 + transposase gene gene2532 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12740 UM146_RS12750 UM146_t23895 UM146_RS12750 2521802 2521878 - tRNA-Arg tRNA gene2533 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12750 UM146_RS12755 UM146_RS12755 UM146_RS12755 2522061 2522715 - hypothetical protein gene gene2534 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12755 UM146_RS12760 UM146_12285 UM146_RS12760 2523386 2523748 + transposase gene gene2535 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12760 UM146_RS12765 UM146_12290 UM146_RS12765 2523787 2524101 - hypothetical protein gene gene2536 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12765 UM146_RS12770 UM146_12295 UM146_RS12770 2524643 2525758 + glycosyl transferase gene gene2537 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12770 UM146_RS12775 UM146_12300 UM146_RS12775 2525898 2529557 + multidrug ABC transporter ATPase gene gene2538 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12775 UM146_RS12780 UM146_12305 UM146_RS12780 2529661 2530890 + enterochelin esterase gene gene2539 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12780 UM146_RS12785 UM146_12310 UM146_RS12785 2530975 2531931 + hypothetical protein gene gene2540 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12785 UM146_RS12790 UM146_12315 UM146_RS12790 2531976 2534159 - outer membrane receptor protein Fep%3B Cbt%3B Cbr%3B FeuB%3B FepA%3B PfeA%3B IroN%3B BfeA%3B outer membrane receptor of ferric enterobactin and colicins B and D%3B interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space gene gene2541 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12790 UM146_RS12795 UM146_RS12795 UM146_RS12795 2534647 2535197 - transcriptional regulator gene gene2542 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12795 UM146_RS12800 UM146_12325 UM146_RS12800 2535344 2536084 - diguanylate phosphodiesterase gene gene2543 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12800 UM146_RS12805 UM146_12330 UM146_RS12805 2536388 2537356 - S-fimbrial protein subunit SfaH gene gene2544 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12805 UM146_RS12810 UM146_12335 UM146_RS12810 2537349 2537840 - S-fimbrial adhesin protein SfaS gene gene2545 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12810 UM146_RS12815 UM146_12340 UM146_RS12815 2537862 2538389 - S-fimbrial protein subunit SfaG gene gene2546 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12815 UM146_RS12820 UM146_12345 UM146_RS12820 2538402 2541032 - fimbrial protein FimD gene gene2547 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12820 UM146_RS12825 UM146_12350 UM146_RS12825 2541102 2541797 - molecular chaperone FimC gene gene2548 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12825 UM146_RS12830 UM146_12355 UM146_RS12830 2541838 2542377 - fimbrin fimI gene gene2549 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12830 UM146_RS12835 UM146_12360 fimA fimA 2542448 2542993 - type-1 fimbrial protein subunit A gene gene2550 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12835 UM146_RS12840 UM146_12365 UM146_RS12840 2543368 2543697 - major pilus subunit operon regulatory protein PapB gene gene2551 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12840 UM146_RS12845 UM146_12370 UM146_RS12845 2544116 2544337 + Major pilus subunit operon regulatory protein gene gene2552 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12845 UM146_RS12850 UM146_12375 UM146_RS12850 2544612 2545181 - hypothetical protein gene gene2553 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12850 UM146_RS12855 UM146_RS12855 UM146_RS12855 2545423 2545935 - hypothetical protein gene gene2554 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12855 UM146_RS12860 UM146_12380 UM146_RS12860 2546232 2546573 + hypothetical protein gene gene2555 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12860 UM146_RS12865 UM146_12385 UM146_RS12865 2546765 2546962 + hydrolase gene gene2556 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12865 UM146_RS12870 UM146_12390 UM146_RS12870 2546981 2547481 + galactarate dehydratase gene gene2557 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12870 UM146_RS12875 UM146_12395 UM146_RS12875 2547544 2547825 - DeoR family transcriptional regulator gene gene2558 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12875 UM146_RS12880 UM146_12400 UM146_RS12880 2547863 2548114 - transcriptional regulator gene gene2559 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12880 UM146_RS12885 UM146_12405 UM146_RS12885 2548363 2548986 + tagatose-6-phosphate ketose isomerase gene gene2560 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12885 UM146_RS12890 UM146_12420 UM146_RS12890 2549411 2550574 + aminotransferase gene gene2561 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12890 UM146_RS12895 UM146_12425 UM146_RS12895 2550600 2552489 + enterotoxin gene gene2562 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12895 UM146_RS12900 UM146_12435 UM146_RS12900 2552658 2552864 - methyltransferase gene gene2563 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12900 UM146_RS12905 UM146_12440 UM146_RS12905 2552966 2553559 - hypothetical protein gene gene2564 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12905 UM146_RS12910 UM146_RS12910 UM146_RS12910 2554515 2555947 - hypothetical protein gene gene2565 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12910 UM146_RS12915 UM146_RS12915 UM146_RS12915 2556166 2556363 - hypothetical protein gene gene2566 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12915 UM146_RS12920 UM146_12455 UM146_RS12920 2556590 2556886 - hypothetical protein gene gene2567 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12920 UM146_RS12925 UM146_12460 UM146_RS12925 2557039 2557503 - transposase gene gene2568 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12925 UM146_RS12930 UM146_12470 UM146_RS12930 2558000 2559817 + membrane protein gene gene2569 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12930 UM146_RS12935 UM146_12475 UM146_RS12935 2560004 2561206 - integrase gene gene2570 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12935 UM146_RS12940 UM146_12480 UM146_RS12940 2561384 2561488 - hypothetical protein gene gene2571 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12940 UM146_RS12945 UM146_12485 UM146_RS12945 2561485 2562852 - diguanylate cyclase gene gene2572 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12945 UM146_RS12950 UM146_12490 pgaA pgaA 2563440 2565863 + poly-beta-1%2C6-N-acetyl-D-glucosamine export protein outer membrane protein essential for the synthesis of poly-beta-1%2C6-N-acetyl-D-glucosamine (PGA)%3B adhesin required for biofilm formation%3B PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface%3B member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia gene gene2573 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12950 UM146_RS12955 UM146_12495 pgaB pgaB 2565872 2567890 + outer membrane N-deacetylase in Yersinia this protein is involved in biofilm formation and hemin adsorption%3B related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1%2C6-N-acetyl-D-glucosamine (PGA) export gene gene2574 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12955 UM146_RS12960 UM146_12500 UM146_RS12960 2567970 2569208 + N-glycosyltransferase predicted polysaccharide polymerase involved in biofilm formation%3B required for the synthesis of the beta-1%2C6-N-acetylglucosamine polysaccharide%3B PgaC%3B in Yersinia the HmsR protein is an inner membrane protein gene gene2575 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12960 UM146_RS12965 UM146_12505 pgaD pgaD 2569210 2569623 + poly-beta-1%2C6-N-acetyl-D-glucosamine biosynthesis protein PgaD in Yersinia this gene is involved in biofilm formation and hemin adsorption%3B in Escherichia coli it is involved in PGA biosynthesis and export gene gene2576 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12965 UM146_RS12970 UM146_12510 UM146_RS12970 2569673 2570461 - hypothetical protein gene gene2577 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12970 UM146_RS12975 UM146_12515 UM146_RS12975 2571087 2572358 - deferrochelatase/peroxidase EfeB gene gene2578 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12975 UM146_RS12980 UM146_12520 UM146_RS12980 2572364 2573491 - iron uptake system component EfeO with EfeUB forms an iron transport system which is silent in E. coli K-12 due to a mutation in EfeU gene gene2579 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12980 UM146_RS12985 UM146_12525 UM146_RS12985 2573549 2574379 - ferrous iron permease EfeU gene gene2580 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12985 UM146_RS12990 UM146_12530 UM146_RS12990 2574599 2576107 - proline:sodium symporter involved in the sodium dependent uptake of proline gene gene2581 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12990 UM146_RS12995 UM146_12535 UM146_RS12995 2576266 2576475 - hypothetical protein gene gene2582 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS12995 UM146_RS13000 UM146_12540 putA putA 2576530 2580492 + bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase proline utilization protein A%3B multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate%3B in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus%3B forms dimers and is a peripherally membrane-associated protein gene gene2583 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13000 UM146_RS13005 UM146_12545 UM146_RS13005 2580532 2581170 - transcriptional regulator gene gene2584 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13005 UM146_RS13010 UM146_12550 UM146_RS13010 2581457 2582548 + pyrimidine monooxygenase RutA gene gene2585 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13010 UM146_RS13015 UM146_12555 UM146_RS13015 2582548 2583240 + peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB gene gene2586 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13015 UM146_RS13020 UM146_12560 UM146_RS13020 2583252 2583638 + aminoacrylate deaminase reactive intermediate detoxification%3B weak enamine/imine deaminase activity gene gene2587 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13020 UM146_RS13025 UM146_12565 UM146_RS13025 2583646 2584446 + aminoacrylate hydrolase gene gene2588 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13025 UM146_RS13030 UM146_12570 UM146_RS13030 2584456 2585046 + malonic semialdehyde reductase RutE gene gene2589 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13030 UM146_RS13035 UM146_12575 UM146_RS13035 2585057 2585551 + FMN reductase gene gene2590 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13035 UM146_RS13040 UM146_RS13040 UM146_RS13040 2585572 2586794 + pyrimidine permease gene gene2591 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13040 UM146_RS13045 UM146_12590 UM146_RS13045 2586877 2587050 - KGG family protein gene gene2592 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13045 UM146_RS13050 UM146_RS13050 UM146_RS13050 2586983 2587219 - hypothetical protein gene gene2593 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13050 UM146_RS13055 UM146_12595 UM146_RS13055 2587423 2588019 + NAD(P)H dehydrogenase (quinone) catalyzes the transfer of electrons from NADH to ubiquinone gene gene2594 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13055 UM146_RS13060 UM146_12600 UM146_RS13060 2588040 2588267 + hypothetical protein gene gene2595 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13060 UM146_RS13065 UM146_12605 UM146_RS13065 2588305 2589546 - glucose-1-phosphatase/inositol phosphatase gene gene2596 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13065 UM146_RS13070 UM146_12610 UM146_RS13070 2590081 2591001 + curved DNA-binding protein functional analog of DnaJ%3B co-chaperone with DnaK%2C molecular chaperone in an adaptive response to environmental stresses other than heat shock gene gene2597 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13070 UM146_RS13075 UM146_12615 UM146_RS13075 2591001 2591306 + chaperone modulatory protein CbpM with CpbA modulates the activity of the dnaK chaperone system%3B interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA gene gene2598 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13075 UM146_RS13080 UM146_12620 torD torD 2591662 2592261 - chaperone protein TorD TorD%3B involved in the biogenesis of torA%3B acts on torA before the insertion of the molybdenum cofactor and%2C as a result%2C probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor gene gene2599 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13080 UM146_RS13085 UM146_12625 UM146_RS13085 2592258 2594804 - trimethylamine N-oxide reductase I catalytic subunit catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine gene gene2600 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13085 UM146_RS13090 UM146_12630 UM146_RS13090 2594804 2595976 - trimethylamine N-oxide reductase cytochrome C subunit with TorA forms the inducible trimethylamine N-oxide reductase which transfers electrons from menaquinones first to TorC then to TorA gene gene2601 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13090 UM146_RS13095 UM146_12635 UM146_RS13095 2596116 2596808 + two-component system response regulator gene gene2602 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13095 UM146_RS13100 UM146_12640 UM146_RS13100 2596781 2597809 - TMAO reductase periplasmic sensory protein associated with the TorRS two-component regulatory system gene gene2603 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13100 UM146_RS13105 UM146_12645 UM146_RS13105 2597922 2600624 + sensor histidine kinase Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide gene gene2604 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13105 UM146_RS13110 UM146_12650 UM146_RS13110 2600707 2601780 + electron transporter YccM gene gene2605 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13110 UM146_RS13115 UM146_12655 UM146_RS13115 2601829 2602002 - protein GnsA gene gene2606 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13115 UM146_RS13120 UM146_12660 UM146_RS13120 2601992 2602222 - cold-shock protein gene gene2607 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13120 UM146_RS13125 UM146_12665 UM146_RS13125 2602396 2602608 - cold-shock protein CspG gene gene2608 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13125 UM146_RS13130 UM146_12670 UM146_RS13130 2602894 2603106 + cold-shock protein CspH gene gene2609 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13130 UM146_RS13135 UM146_12675 UM146_RS13135 2603094 2604404 - phosphoanhydride phosphorylase gene gene2610 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13135 UM146_RS13140 UM146_12680 UM146_RS13140 2604484 2604576 - cytochrome bd-II oxidase subunit gene gene2611 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13140 UM146_RS13145 UM146_12685 UM146_RS13145 2604589 2605725 - cytochrome bd-II ubiquinol oxidase subunit 2 gene gene2612 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13145 UM146_RS13150 UM146_12690 UM146_RS13150 2605737 2607281 - cytochrome BD oxidase subunit I part of the aerobic respiratory chain%3B catalyzes the ubiquinol to ubiquinone gene gene2613 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13150 UM146_RS13155 UM146_12695 UM146_RS13155 2607415 2608272 - hydrogenase-1 operon protein HyaF gene gene2614 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13155 UM146_RS13160 UM146_12700 UM146_RS13160 2608269 2608667 - hydrogenase-1 operon protein HyaE involved in processing hydrogenase proteins HyaA and HyaB gene gene2615 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13160 UM146_RS13165 UM146_12705 UM146_RS13165 2608664 2609251 - hydrogenase 1 maturation protease HyaD%3B endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1) gene gene2616 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13165 UM146_RS13170 UM146_12710 UM146_RS13170 2609248 2609955 - hydrogenase 1 b-type cytochrome subunit gene gene2617 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13170 UM146_RS13175 UM146_12715 UM146_RS13175 2609974 2611767 - hydrogenase 2 large subunit gene gene2618 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13175 UM146_RS13180 UM146_12720 UM146_RS13180 2611764 2612882 - hydrogenase gene gene2619 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13180 UM146_RS13185 UM146_t23897 UM146_RS13185 2613309 2613396 + tRNA-Ser tRNA gene2620 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13185 UM146_RS13190 UM146_12725 UM146_RS13190 2613603 2614262 + Modulator of FtsH protease inner membrane protein binds to the HflBKC complex which modulates FtsH activity gene gene2621 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13190 UM146_RS13195 UM146_12730 UM146_RS13195 2614354 2614683 + sulfurtransferase TusE transfers sulfur from TusBCD complex to MnmA%3B involved in thiouridation of U34 position of some tRNAs gene gene2622 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13195 UM146_RS13200 UM146_12735 UM146_RS13200 2614680 2614958 - acylphosphatase catalyzes the hydrolysis of acylphosphate gene gene2623 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13200 UM146_RS13205 UM146_12740 UM146_RS13205 2615053 2616243 + ribosomal RNA large subunit methyltransferase I SAM-dependent%3Bcatalyzes the methylation of cytosine at position 1962 of the 23S rRNA gene gene2624 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13205 UM146_RS13210 UM146_12745 UM146_RS13210 2616301 2616618 + heat-shock protein HspQ gene gene2625 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13210 UM146_RS13215 UM146_12750 UM146_RS13215 2616663 2617076 - hypothetical protein gene gene2626 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13215 UM146_RS13220 UM146_RS13220 UM146_RS13220 2617039 2617209 + hypothetical protein gene gene2627 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13220 UM146_RS13225 UM146_12755 UM146_RS13225 2617249 2617911 + hypothetical protein gene gene2628 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13225 UM146_RS13230 UM146_12760 mgsA mgsA 2618007 2618465 + methylglyoxal synthase catalyzes the formation of methylglyoxal from glycerone phosphate gene gene2629 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13230 UM146_RS13235 UM146_12765 helD helD 2618497 2620551 - DNA helicase IV catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand gene gene2630 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13235 UM146_RS13240 UM146_12770 UM146_RS13240 2620674 2621120 + membrane protein gene gene2631 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13240 UM146_RS13245 UM146_12775 UM146_RS13245 2621139 2623292 + membrane protein gene gene2632 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13245 UM146_RS13250 UM146_12780 UM146_RS13250 2623255 2623884 - Crp/Fnr family transcriptional regulator gene gene2633 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13250 UM146_RS13255 UM146_12785 UM146_RS13255 2624103 2624612 + cell division inhibitor SulA gene gene2634 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13255 UM146_RS13260 UM146_RS13260 UM146_RS13260 2624596 2624766 - hypothetical protein gene gene2635 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13260 UM146_RS13265 UM146_12790 UM146_RS13265 2624968 2626008 + membrane protein OmpA is believed to be a porin%2C involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli%2C and it is known to play a role as a phage receptor%2C a mediator of F-factor dependent conjugation%2C and in maintaining the structural shape of the outer membrane%3B 3a%3B II*%3B G%3B d gene gene2636 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13265 UM146_RS13270 UM146_12795 UM146_RS13270 2626085 2626537 - macrodomain Ter protein gene gene2637 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13270 UM146_RS13275 UM146_12800 UM146_RS13275 2626723 2628483 + lon protease gene gene2638 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13275 UM146_RS13280 UM146_12805 UM146_RS13280 2628552 2629070 + 3-hydroxydecanoyl-ACP dehydratase catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2%2C3-decenoyl-ACP or 3%2C4-decenoyl-ACP gene gene2639 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13280 UM146_RS13285 UM146_12810 UM146_RS13285 2629140 2629307 - ribosome modulation factor gene gene2640 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13285 UM146_RS13290 UM146_12815 UM146_RS13290 2629562 2630125 - hypothetical protein gene gene2641 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13290 UM146_RS13295 UM146_12820 UM146_RS13295 2630122 2631762 - paraquat-inducible protein B gene gene2642 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13295 UM146_RS13300 UM146_12825 UM146_RS13300 2631767 2633020 - paraquat-inducible protein A gene gene2643 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13300 UM146_RS13305 UM146_12830 UM146_RS13305 2633150 2635057 - ABC transporter ATP-binding protein Uup%3B in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity%3B mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth gene gene2644 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13305 UM146_RS13310 UM146_12835 rlmL rlmL 2635069 2637177 - ribosomal RNA large subunit methyltransferase K/L catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA gene gene2645 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13310 UM146_RS13315 UM146_12840 UM146_RS13315 2637275 2638384 + hypothetical protein gene gene2646 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13315 UM146_RS13320 UM146_12845 UM146_RS13320 2638381 2638923 - cell division protein ZapC gene gene2647 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13320 UM146_RS13325 UM146_12850 UM146_RS13325 2639097 2640107 - dihydroorotate dehydrogenase catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway%3B uses a flavin nucleotide as an essential cofactor%3B class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus%2C which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors gene gene2648 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13325 UM146_RS13330 UM146_12855 UM146_RS13330 2640344 2640919 + FMN reductase gene gene2649 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13330 UM146_RS13335 UM146_RS13335 UM146_RS13335 2640912 2641870 + alkanesulfonate transporter substrate-binding subunit part of the ABC type transport system SsuABC for aliphatic sulfonates%3B with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease gene gene2650 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13335 UM146_RS13340 UM146_12870 UM146_RS13340 2641867 2643012 + alkanesulfonate monooxygenase catalyzes the release of sulfite from alkanesulfonates gene gene2651 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13340 UM146_RS13345 UM146_12875 ssuC ssuC 2643024 2643815 + sulfonate ABC transporter part of the ABC type transport system for alkanesulfonate SsuABC%3B SsuB the ATP-binding subunit and SsuC the permease gene gene2652 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13345 UM146_RS13350 UM146_12880 ssuB ssuB 2643812 2644579 + aliphatic sulfonate ABC transporter ATP-binding protein part of the ABC type transport system SsuABC for aliphatic sulfonates%3B with SsuA being the periplasmic substrate-binding subunit%2C SsuB the ATP-binding subunit and SsuC the permease gene gene2653 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13350 UM146_RS13355 UM146_12885 pepN pepN 2644774 2647386 - aminopeptidase N gene gene2654 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13355 UM146_RS13360 UM146_12890 UM146_RS13360 2647652 2648854 + nicotinate phosphoribosyltransferase catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate gene gene2655 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13360 UM146_RS13365 UM146_12895 UM146_RS13365 2649022 2650422 + asparagine--tRNA ligase gene gene2656 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13365 UM146_RS13370 UM146_12900 UM146_RS13370 2651024 2652112 + phosphoporin protein E gene gene2657 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13370 UM146_RS13375 UM146_12905 UM146_RS13375 2652109 2652309 - hypothetical protein gene gene2658 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13375 UM146_RS13380 UM146_12910 UM146_RS13380 2652296 2653486 + aspartate aminotransferase gene gene2659 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13380 UM146_RS13385 UM146_12915 UM146_RS13385 2653536 2654183 - hypothetical protein gene gene2660 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13385 UM146_RS13390 UM146_12920 UM146_RS13390 2654210 2654758 - M15A protease-related family periplasmic protein gene gene2661 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13390 UM146_RS13395 UM146_12925 UM146_RS13395 2654939 2656786 - murein transpeptidase catalyzes the formation of a meso-diaminopimelyl- meso-diaminopimelyl crosslink gene gene2662 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13395 UM146_RS13400 UM146_12930 mukB mukB 2657047 2661507 - chromosome partition protein MukB SMC (structural maintenance of chromosomes) family of proteins%3B involved in chromosome condensatin and partitioning%3B forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ%3B mutations result in cell division defects gene gene2663 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13400 UM146_RS13405 UM146_12935 UM146_RS13405 2661507 2662211 - condesin subunit E acts with MukB and MukF to condense the chromosome and allow for segregation during cell division gene gene2664 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13405 UM146_RS13410 UM146_12940 UM146_RS13410 2662192 2663514 - chromosome partition protein MukF acts with MukB and MukE to condense the chromosome and allow for segregation during cell division gene gene2665 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13410 UM146_RS13415 UM146_12945 UM146_RS13415 2663511 2664296 - S-adenosyl-L-methionine-dependent methyltransferase gene gene2666 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13415 UM146_RS13420 UM146_12950 UM146_RS13420 2664432 2665211 + envelope biogenesis factor ElyC gene gene2667 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13420 UM146_RS13425 UM146_12955 UM146_RS13425 2665188 2666081 - hypothetical protein gene gene2668 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13425 UM146_RS13430 UM146_12960 UM146_RS13430 2666235 2666981 - 3-deoxy-manno-octulosonate cytidylyltransferase CMP-2-keto-3-deoxyoctulosonic acid synthetase%3B catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS gene gene2669 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13430 UM146_RS13435 UM146_12965 UM146_RS13435 2666978 2667160 - hypothetical protein gene gene2670 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13435 UM146_RS13440 UM146_12970 UM146_RS13440 2667212 2668444 - hypothetical protein gene gene2671 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13440 UM146_RS13445 UM146_12975 lpxK lpxK 2668481 2669467 - tetraacyldisaccharide 4'-kinase transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1%2C4'-bis-phosphate gene gene2672 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13445 UM146_RS13450 UM146_12980 UM146_RS13450 2669464 2671212 - ATP-binding protein involved in the transport of lipid A across the inner membrane gene gene2673 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13450 UM146_RS13455 UM146_12985 UM146_RS13455 2671249 2673513 - competence protein ComEC gene gene2674 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13455 UM146_RS13460 UM146_12990 ihfB ihfB 2673719 2674003 - integration host factor subunit beta This protein is one of the two subunits of integration host factor%2C a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control gene gene2675 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13460 UM146_RS13465 UM146_12995 rpsA rpsA 2674163 2675836 - 30S ribosomal protein S1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit%3B autoregulates expression via a C-terminal domain%3B in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats%3B the S1 nucleic acid-binding domain is found associated with other proteins gene gene2676 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13465 UM146_RS13470 UM146_13000 cmk cmk 2675947 2676630 - cytidylate kinase Catalyzes the formation of (d)CDP from ATP and (d)CMP gene gene2677 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13470 UM146_RS13475 UM146_13005 UM146_RS13475 2676803 2677567 - metalloprotease gene gene2678 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13475 UM146_RS13480 UM146_13010 UM146_RS13480 2677736 2679019 - 3-phosphoshikimate 1-carboxyvinyltransferase gene gene2679 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13480 UM146_RS13485 UM146_13015 UM146_RS13485 2679090 2680178 - phosphoserine aminotransferase catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate%3B catalyzes 4 phosphohydroxy L-threonine from 2-oxo 3 hydroxy 4- phosphobutanoate%3B required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine gene gene2680 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13485 UM146_RS13490 UM146_13020 UM146_RS13490 2680377 2681069 - membrane protein gene gene2681 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13490 UM146_RS13495 UM146_13025 UM146_RS13495 2681199 2682959 + hypothetical protein gene gene2682 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13495 UM146_RS13500 UM146_13030 UM146_RS13500 2683365 2684222 + formate transporter FocA gene gene2683 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13500 UM146_RS13505 UM146_13035 UM146_RS13505 2684277 2686559 + formate acetyltransferase 1 formate acetyltransferase%3B catalyzes the formation of formate and acetyl-CoA from pyruvate gene gene2684 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13505 UM146_RS13510 UM146_13040 pflA pflA 2686751 2687491 + pyruvate formate-lyase 1-activating enzyme activates pyruvate formate-lyase 1 under anaerobic conditions gene gene2685 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13510 UM146_RS13515 UM146_13045 UM146_RS13515 2687588 2688736 - MFS transporter gene gene2686 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13515 UM146_RS13520 UM146_13050 UM146_RS13520 2689050 2689676 + hypothetical protein gene gene2687 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13520 UM146_RS13525 UM146_13055 UM146_RS13525 2689712 2690575 - dimethyl sulfoxide reductase subunit C gene gene2688 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13525 UM146_RS13530 UM146_13060 UM146_RS13530 2690577 2691194 - dimethyl sulfoxide reductase subunit B oxidoreductase%2C Fe-S subunit%3B terminal electron transfer protein for the reduction of DMSO gene gene2689 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13530 UM146_RS13535 UM146_13065 UM146_RS13535 2691205 2693649 - dimethyl sulfoxide reductase subunit A gene gene2690 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13535 UM146_RS13540 UM146_13070 UM146_RS13540 2693888 2695180 - serine--tRNA ligase gene gene2691 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13540 UM146_RS13545 UM146_13075 UM146_RS13545 2695271 2696614 - recombinase RarA gene gene2692 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13545 UM146_RS13550 UM146_13080 lolA lolA 2696625 2697236 - outer membrane lipoprotein carrier protein LolA participates with LolB in the incorporation of lipoprotein into the outer membrane gene gene2693 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13550 UM146_RS13555 UM146_13085 UM146_RS13555 2697395 2701438 - cell division protein FtsK DNA-binding membrane protein required for chromosome resolution and partitioning gene gene2694 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13555 UM146_RS13560 UM146_13090 UM146_RS13560 2701573 2702067 - leucine-responsive regulatory protein mediates a global response to leucine%3B acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system gene gene2695 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13560 UM146_RS13565 UM146_13095 UM146_RS13565 2702610 2703575 + thioredoxin reductase catalyzes the transfer of electrons from NADPH to thioredoxin%3B FAD/NAD(P) binding gene gene2696 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13565 UM146_RS13570 UM146_13100 UM146_RS13570 2703697 2705463 + glutathione ABC transporter ATP-binding protein in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance%3B important for cytochrome bd and c gene gene2697 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13570 UM146_RS13575 UM146_13105 UM146_RS13575 2705464 2707185 + glutathione ABC transporter ATP-binding protein in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance%3B important for cytochrome bd and c gene gene2698 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13575 UM146_RS13580 UM146_13110 aat aat 2707227 2707931 + leucyl/phenylalanyl-tRNA--protein transferase leucyltransferase%3B phenylalanyltransferse%3B functions in the N-end rule pathway%3B transfers Leu%2C Phe%2C Met%2C from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys gene gene2699 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13580 UM146_RS13585 UM146_13115 UM146_RS13585 2708216 2708434 + translation initiation factor IF-1 gene gene2700 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13585 UM146_RS13590 UM146_t23899 UM146_RS13590 2709278 2709365 + tRNA-Ser tRNA gene2701 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13590 UM146_RS13595 UM146_13120 UM146_RS13595 2709475 2710029 - CRISPR-associated endonuclease Cas6/Csy4 gene gene2702 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13595 UM146_RS13600 UM146_13125 UM146_RS13600 2710040 2711041 - CRISPR-associated protein Cas5 gene gene2703 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13600 UM146_RS13605 UM146_RS13605 UM146_RS13605 2711052 2711975 - CRISPR-associated protein gene gene2704 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13605 UM146_RS13610 UM146_13140 UM146_RS13610 2711972 2713279 - CRISPR type I-F system protein Csy1 gene gene2705 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13610 UM146_RS13615 UM146_13145 UM146_RS13615 2713609 2716842 - CRISPR-associated protein Cas3 gene gene2706 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13615 UM146_RS13620 UM146_13150 UM146_RS13620 2716839 2717822 - subtype I-F CRISPR-associated endonuclease Cas1 gene gene2707 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13620 UM146_RS13625 UM146_13155 clpA clpA 2718715 2720991 - ATP-dependent Clp protease ATP-binding subunit ClpA ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease%3B directs protease to specific substrates gene gene2708 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13625 UM146_RS13630 UM146_13160 clpS clpS 2721022 2721342 - ATP-dependent Clp protease adapter protein ClpS involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation%3B binds to the N-terminal domain of the chaperone ClpA gene gene2709 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13630 UM146_RS13635 UM146_RS13635 UM146_RS13635 2721706 2722043 + hypothetical protein gene gene2710 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13635 UM146_RS13640 UM146_RS13640 UM146_RS13640 2722035 2722316 - hypothetical protein gene gene2711 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13640 UM146_RS13645 UM146_13175 UM146_RS13645 2722573 2723085 - terminase gene gene2712 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13645 UM146_RS13650 UM146_13180 UM146_RS13650 2723322 2723735 - hypothetical protein gene gene2713 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13650 UM146_RS13655 UM146_13185 UM146_RS13655 2723748 2724083 - phage capsid protein gene gene2714 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13655 UM146_RS13660 UM146_13190 UM146_RS13660 2724095 2725150 - phage capsid protein gene gene2715 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13660 UM146_RS13665 UM146_13195 UM146_RS13665 2725150 2725356 - hypothetical protein gene gene2716 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13665 UM146_RS13675 UM146_13200 UM146_RS13675 2725772 2726194 - single-stranded DNA-binding protein gene gene2717 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13675 UM146_RS13680 UM146_13205 UM146_RS13680 2726191 2726448 - hypothetical protein gene gene2718 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13680 UM146_RS13685 UM146_13210 UM146_RS13685 2726737 2728344 - DNA primase gene gene2719 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13685 UM146_RS13690 UM146_13215 UM146_RS13690 2728481 2728780 - hypothetical protein gene gene2720 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13690 UM146_RS13695 UM146_13220 UM146_RS13695 2728786 2729013 - hypothetical protein gene gene2721 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13695 UM146_RS13700 UM146_13225 UM146_RS13700 2729006 2729347 - hypothetical protein gene gene2722 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13700 UM146_RS13705 UM146_RS13705 UM146_RS13705 2729530 2729853 - hypothetical protein gene gene2724 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13705 UM146_RS13710 UM146_13235 UM146_RS13710 2729933 2730142 - DNA-binding protein gene gene2725 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13710 UM146_RS13715 UM146_13240 UM146_RS13715 2730562 2731800 - integrase gene gene2726 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13715 UM146_RS13720 UM146_13245 UM146_RS13720 2732205 2732429 + cold-shock protein CspD inhibits DNA replication at both initiation and elongation steps%3B stationary phase and starvation inducible gene gene2727 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13720 UM146_RS13725 UM146_13250 UM146_RS13725 2732502 2734448 - MacB family efflux pump subunit with MacA is involved in the export of macrolide gene gene2728 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13725 UM146_RS13730 UM146_13255 UM146_RS13730 2734445 2735560 - MacA family efflux pump subunit confers macrolide resistance via active drug efflux gene gene2729 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13730 UM146_RS13735 UM146_13260 UM146_RS13735 2735675 2736667 + hypothetical protein gene gene2730 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13735 UM146_RS13740 UM146_13265 UM146_RS13740 2736664 2738322 - hypothetical protein gene gene2731 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13740 UM146_RS13745 UM146_13270 UM146_RS13745 2738380 2738535 + hypothetical protein gene gene2732 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13745 UM146_RS13750 UM146_13275 UM146_RS13750 2738748 2739443 + aquaporin Z porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure gene gene2733 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13750 UM146_RS13755 UM146_13280 UM146_RS13755 2739764 2740663 + membrane protein gene gene2734 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13755 UM146_RS13760 UM146_13285 UM146_RS13760 2740807 2742459 + hydroxylamine reductase gene gene2735 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13760 UM146_RS13765 UM146_13290 UM146_RS13765 2742471 2743439 + oxidoreductase gene gene2736 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13765 UM146_RS13770 UM146_13295 UM146_RS13770 2743572 2745290 + pyruvate dehydrogenase catalyzes the formation of acetate from pyruvate gene gene2737 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13770 UM146_RS13775 UM146_13300 UM146_RS13775 2745327 2746328 + threonine aldolase low- specificity%3B catalyzes the formation of acetaldehyde and glycine from L-threonine%3B acts on L-threonine%2C L-allo-threonine%2C L-threo-phenylserine%2C and L-erythro-phenylserine gene gene2738 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13775 UM146_RS13780 UM146_13305 UM146_RS13780 2746339 2747769 + hypothetical protein gene gene2739 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13780 UM146_RS13785 UM146_13310 UM146_RS13785 2747868 2748881 + hypothetical protein gene gene2740 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13785 UM146_RS13790 UM146_13315 UM146_RS13790 2748878 2749708 - N-acetylmuramoyl-L-alanine amidase catalyzes the cleavage of the bond between muamic acid and l-alanine gene gene2741 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13790 UM146_RS13795 UM146_13320 UM146_RS13795 2749705 2750028 - hypothetical protein gene gene2742 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13795 UM146_RS13800 UM146_13325 UM146_RS13800 2750154 2750669 + lipoprotein induced during stationary phase and by acivicin (a glutamine analog)%3B regulated by Lrp and RpoS gene gene2743 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13800 UM146_RS13805 UM146_13330 UM146_RS13805 2750887 2751615 + arginine transport ATP-binding protein ArtP gene gene2744 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13805 UM146_RS13810 UM146_RS13810 UM146_RS13810 2751617 2752363 + arginine ABC transporter substrate-binding protein with ArtPMQI is involved in arginine transport gene gene2745 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13810 UM146_RS13815 UM146_13340 UM146_RS13815 2752370 2753086 + arginine transporter permease subunit ArtQ with ArtPMJI transports arginine across the inner membrane gene gene2746 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13815 UM146_RS13820 UM146_13345 artM artM 2753086 2753754 + arginine ABC transporter permease ArtM with ArtPQJI acts to transport arginine across the inner membrane gene gene2747 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13820 UM146_RS13825 UM146_13350 UM146_RS13825 2753980 2754711 + arginine ABC transporter substrate-binding protein with ArtPMQI is involved in arginine transport gene gene2748 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13825 UM146_RS13830 UM146_13355 rumB rumB 2754740 2755867 - 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC RNA uridine methyltransferase B%3B catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA gene gene2749 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13830 UM146_RS13835 UM146_13360 UM146_RS13835 2755908 2756396 - hypothetical protein gene gene2750 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13835 UM146_RS13840 UM146_13365 UM146_RS13840 2756456 2757301 - spermidine/putrescine ABC transporter permease gene gene2751 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13840 UM146_RS13845 UM146_13370 UM146_RS13845 2757298 2758251 - putrescine/spermidine ABC transporter permease gene gene2752 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13845 UM146_RS13850 UM146_13375 potG potG 2758261 2759394 - putrescine/spermidine ABC transporter ATP-binding protein part of the PotFGHI ATP-dependent putrescine transporter gene gene2753 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13850 UM146_RS13855 UM146_13380 UM146_RS13855 2759489 2760601 - putrescine/spermidine ABC transporter substrate-binding protein gene gene2754 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13855 UM146_RS13860 UM146_RS13860 UM146_RS13860 2760585 2760745 - putrescine/spermidine ABC transporter substrate-binding protein gene gene2755 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13860 UM146_RS13865 UM146_13385 UM146_RS13865 2760951 2761427 - negative regulator of motility%3B multicopy suppressor of coaA(Ts) gene gene2756 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13865 UM146_RS13870 UM146_13390 UM146_RS13870 2761515 2762417 - ribosomal protein S6--L-glutamate ligase responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 gene gene2757 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13870 UM146_RS13875 UM146_13395 UM146_RS13875 2762478 2763200 - nitroreductase A NADPH-dependent%3B oxygen-insensitive%3B catalyzes the reduction of nitroaromatic compounds gene gene2758 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13875 UM146_RS13880 UM146_13400 UM146_RS13880 2763184 2763471 - hypothetical protein YbjC%3B located in the same operon as the nfsA gene%3B member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress%3B induced by paraquat%3B regulated by SoxS%3B unknown function gene gene2759 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13880 UM146_RS13885 UM146_13405 UM146_RS13885 2763631 2763888 + glutaredoxin functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase%3B also involved in reducing some disulfides in a coupled system with glutathione reductase gene gene2760 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13885 UM146_RS13890 UM146_13410 UM146_RS13890 2763918 2764295 - membrane protein gene gene2761 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13890 UM146_RS13895 UM146_13415 UM146_RS13895 2764565 2766250 + transporter gene gene2762 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13895 UM146_RS13900 UM146_13420 UM146_RS13900 2766425 2766961 - DNA-binding transcriptional regulator gene gene2763 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13900 UM146_RS13905 UM146_13425 UM146_RS13905 2767045 2768253 + hypothetical protein gene gene2764 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13905 UM146_RS13910 UM146_13430 UM146_RS13910 2768253 2769068 + sugar phosphatase SupH gene gene2765 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13910 UM146_RS13915 UM146_13435 UM146_RS13915 2769159 2769419 + hypothetical protein gene gene2766 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13915 UM146_RS13920 UM146_13440 UM146_RS13920 2769460 2770692 - multidrug transporter MdfA gene gene2767 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13920 UM146_RS13925 UM146_13445 UM146_RS13925 2770977 2771573 + UDP pyrophosphate phosphatase gene gene2768 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13925 UM146_RS13930 UM146_13450 UM146_RS13930 2771631 2772389 + DeoR family transcriptional regulator gene gene2769 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13930 UM146_RS13935 UM146_13455 UM146_RS13935 2772436 2773638 - D-alanyl-D-alanine carboxypeptidase gene gene2770 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13935 UM146_RS13940 UM146_13460 UM146_RS13940 2773885 2774511 + glutathione S-transferase gene gene2771 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13940 UM146_RS13945 UM146_13465 UM146_RS13945 2774508 2775623 - aldose dehydrogenase gene gene2772 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13945 UM146_RS13950 UM146_13470 bssR bssR 2775734 2776117 - biofilm regulator BssR BssS%3B regulator of biofilm through signal secretion%3B disruption of this gene in Escherichia coli led to effects on biofilm formation%2C alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing gene gene2773 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13950 UM146_RS13955 UM146_13475 rimO rimO 2776330 2777655 + ribosomal protein S12 methylthiotransferase RimO catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit gene gene2774 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13955 UM146_RS13960 UM146_13480 UM146_RS13960 2777702 2779030 - hypothetical protein gene gene2775 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13960 UM146_RS13965 UM146_13485 UM146_RS13965 2779038 2781386 - cyclic di-GMP phosphodiesterase gene gene2776 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13965 UM146_RS13970 UM146_13490 UM146_RS13970 2781563 2782474 - glutathione ABC transporter permease with GsiABD is involved in the transport of glutathione into the cell gene gene2777 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13970 UM146_RS13975 UM146_13495 UM146_RS13975 2782477 2783397 - glutathione ABC transporter permease with GsiABD is involved in the transport of glutathione into the cell gene gene2778 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13975 UM146_RS13980 UM146_13500 UM146_RS13980 2783415 2784953 - glutathione-binding protein GsiB with GsiACD is involved in the transport of glutathione into the cell gene gene2779 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13980 UM146_RS13985 UM146_13505 UM146_RS13985 2784973 2786844 - glutathione import ATP-binding protein GsiA with GsiBCD is involved in glutathione import%3B GsiA contains 2 ATP-binding domains gene gene2780 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13985 UM146_RS13990 UM146_13510 UM146_RS13990 2786831 2787796 - isoaspartyl peptidase gene gene2781 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13990 UM146_RS13995 UM146_13515 UM146_RS13995 2788000 2789235 + molybdopterin biosynthesis protein MoeA is involved in the formation of active molybdenum cofactor and the chelation of molybdenum gene gene2782 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS13995 UM146_RS14000 UM146_13520 UM146_RS14000 2789235 2789984 + molybdopterin-synthase adenylyltransferase gene gene2783 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14000 UM146_RS14005 UM146_13525 UM146_RS14005 2790060 2790722 - fructose-6-phosphate aldolase similar to transaldolase from Escherichia coli%3B many organisms have multiple copies gene gene2784 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14005 UM146_RS14010 UM146_13530 UM146_RS14010 2790853 2791752 + pyruvate formate-lyase 3-activating protein gene gene2785 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14010 UM146_RS14015 UM146_13535 UM146_RS14015 2791758 2794190 + formate acetyltransferase gene gene2786 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14015 UM146_RS14020 UM146_13540 UM146_RS14020 2794336 2795151 + sugar phosphatase gene gene2787 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14020 UM146_RS14025 UM146_13545 UM146_RS14025 2795351 2796943 - ABC transporter ATP-binding protein gene gene2788 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14025 UM146_RS14030 UM146_13550 UM146_RS14030 2797162 2798082 + transpeptidase gene gene2789 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14030 UM146_RS14035 UM146_13555 UM146_RS14035 2798140 2799258 - hypothetical protein gene gene2790 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14035 UM146_RS14040 UM146_13560 UM146_RS14040 2799255 2799722 - transcriptional regulator MntR Transcriptional regulator that represses the manganese transporter MntH when manganese is present gene gene2791 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14040 UM146_RS14045 UM146_13565 UM146_RS14045 2799908 2800036 + small protein MntS gene gene2792 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14045 UM146_RS14050 UM146_13570 UM146_RS14050 2800308 2801891 + phosphoethanolamine transferase gene gene2793 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14050 UM146_RS14055 UM146_13575 ompX ompX 2801941 2802456 - outer membrane protein X OmpX%3B involved in cell adhesion%3B forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface%3B mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains gene gene2794 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14055 UM146_RS14060 UM146_13580 UM146_RS14060 2802809 2803696 + threonine/homoserine exporter RhtA gene gene2795 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14060 UM146_RS14065 UM146_13585 UM146_RS14065 2803995 2804498 + DNA protection during starvation protein binds DNA in a non-sequence-specific manner and is abundant during stationary phase%3B forms a DNA-protein crystal that protects DNA from damage%3B required for normal starvation response and long-term stationary viability%3B forms a homododecameric complex and sequesters iron which provides protection against oxidative damage gene gene2796 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14065 UM146_RS14070 UM146_RS14070 UM146_RS14070 2804563 2804856 + hypothetical protein gene gene2797 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14070 UM146_RS14075 UM146_13590 glnH glnH 2804902 2805648 + glutamine-binding periplasmic protein similar to periplasmic-binding component of ABC transporters gene gene2798 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14075 UM146_RS14080 UM146_13595 glnP glnP 2805787 2806446 + glutamine ABC transporter permease similar to permease component of ABC transporters%3B mutations impair ability of Escherichia coli to transport and utilize glutamine gene gene2799 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14080 UM146_RS14085 UM146_13600 glnQ glnQ 2806443 2807165 + glutamine ABC transporter ATP-binding protein similar to ATP-binding component of ABC transporters gene gene2800 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14085 UM146_RS14090 UM146_13605 UM146_RS14090 2807282 2809507 + mechanosensitive channel protein gene gene2801 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14090 UM146_RS14095 UM146_13610 UM146_RS14095 2809504 2810430 - ribosomal RNA large subunit methyltransferase F gene gene2802 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14095 UM146_RS14100 UM146_13615 UM146_RS14100 2810706 2810966 + hypothetical protein gene gene2803 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14100 UM146_RS14105 UM146_13620 UM146_RS14105 2811231 2813513 + catecholate siderophore receptor Fiu Fiu%3B YbiL%3B porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine%2C dihydroxybenzoate) and beta lactam agents%3B Fiu interacts with TonB which provides the energy required for transport across the outer membrane%3B acts as a receptor for iron-siderophores and microcins E492%2C M%2C and H47%3B outer membrane protein gene gene2804 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14105 UM146_RS14110 UM146_13625 UM146_RS14110 2813729 2814406 + PKHD-type hydroxylase gene gene2805 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14110 UM146_RS14115 UM146_13630 UM146_RS14115 2814480 2814746 + hypothetical protein gene gene2806 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14115 UM146_RS14120 UM146_13635 UM146_RS14120 2815010 2815270 + hypothetical protein gene gene2807 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14120 UM146_RS14125 UM146_13640 UM146_RS14125 2815498 2816583 - dehydrogenase gene gene2808 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14125 UM146_RS14130 UM146_13645 UM146_RS14130 2816723 2817685 - glycosyl transferase gene gene2809 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14130 UM146_RS14135 UM146_13650 dinG dinG 2817713 2819863 - ATP-dependent helicase DinG helicase involved in DNA repair and perhaps also replication gene gene2810 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14135 UM146_RS14140 UM146_13655 UM146_RS14140 2819862 2820167 + hypothetical protein gene gene2811 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14140 UM146_RS14145 UM146_13660 UM146_RS14145 2820400 2821761 - RNA helicase this helicase is not essential cell growth gene gene2812 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14145 UM146_RS14150 UM146_13665 UM146_RS14150 2821990 2822661 + transcriptional regulator gene gene2813 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14150 UM146_RS14155 UM146_13670 UM146_RS14155 2822664 2823659 + transporter gene gene2814 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14155 UM146_RS14160 UM146_13675 UM146_RS14160 2823652 2825388 + multidrug ABC transporter ATP-binding protein gene gene2815 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14160 UM146_RS14165 UM146_13680 UM146_RS14165 2825381 2826514 + hypothetical protein gene gene2816 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14165 UM146_RS14170 UM146_13685 UM146_RS14170 2826525 2827631 + inner membrane transport permease YbhR gene gene2817 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14170 UM146_RS14175 UM146_13690 UM146_RS14175 2827593 2828003 - hypothetical protein gene gene2818 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14175 UM146_RS14180 UM146_13695 UM146_RS14180 2828136 2828897 + hypothetical protein gene gene2819 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14180 UM146_RS14185 UM146_13700 UM146_RS14185 2828894 2830135 + cardiolipin synthase 2 gene gene2820 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14185 UM146_RS14190 UM146_13705 UM146_RS14190 2830135 2831091 + hypothetical protein gene gene2821 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14190 UM146_RS14195 UM146_13710 UM146_RS14195 2831127 2831840 - hypothetical protein gene gene2822 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14195 UM146_RS14200 UM146_13715 UM146_RS14200 2832045 2832749 - hypothetical protein gene gene2823 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14200 UM146_RS14205 UM146_13720 moaE moaE 2832886 2833338 - molybdopterin guanine dinucleotide biosynthesis protein MoaE catalyzes the conversion of molybdopterin precursor Z into molybdopterin gene gene2824 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14205 UM146_RS14210 UM146_13725 moaD moaD 2833340 2833585 - molybdopterin synthase small subunit catalyzes the conversion of molybdopterin precursor Z into molybdopterin gene gene2825 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14210 UM146_RS14215 UM146_13730 moaC moaC 2833578 2834063 - cyclic pyranopterin monophosphate synthase accessory protein MoaC%3B along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z%3B involved in molybdenum cofactor biosynthesis gene gene2826 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14215 UM146_RS14220 UM146_13735 UM146_RS14220 2834066 2834578 - molybdenum cofactor biosynthesis protein B gene gene2827 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14220 UM146_RS14225 UM146_13740 moaA moaA 2834600 2835589 - cyclic pyranopterin monophosphate synthase together with moaC%2C is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z gene gene2828 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14225 UM146_RS14230 UM146_RS14230 UM146_RS14230 2835588 2835743 + hypothetical protein gene gene2829 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14230 UM146_RS14235 UM146_13750 UM146_RS14235 2835986 2836894 + hypothetical protein gene gene2830 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14235 UM146_RS14240 UM146_13755 UM146_RS14240 2836932 2838953 - UvrABC system protein B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands%2C where it probes for the presence of a lesion gene gene2831 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14240 UM146_RS14245 UM146_13760 bioD bioD 2839532 2840209 - dithiobiotin synthetase DTB synthetase%3B dethiobiotin synthase%3B involved in production of dethiobiotin from ATP and 7%2C8-diaminononanoate and carbon dioxide%3B contains magnesium gene gene2832 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14245 UM146_RS14250 UM146_13765 UM146_RS14250 2840202 2840957 - malonyl-[acyl-carrier protein] O-methyltransferase BioC methyltransferase%3B acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA%2C a biotin precursor%3B member of the bio operon (bioABFCD)%3B in Escherichia coli%2C bioC-null mutants require biotin for growth gene gene2833 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14250 UM146_RS14255 UM146_13770 UM146_RS14255 2840944 2842098 - 8-amino-7-oxononanoate synthase catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine gene gene2834 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14255 UM146_RS14260 UM146_13775 UM146_RS14260 2842095 2843135 - biotin synthase catalyzes the formation of biotin from dethiobiotin gene gene2835 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14260 UM146_RS14265 UM146_13780 UM146_RS14265 2843279 2844511 + adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7%2C8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate gene gene2836 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14265 UM146_RS14270 UM146_13785 UM146_RS14270 2844570 2845046 + kinase inhibitor protein YbhB%3B similar to rat and human kinase inhibitory proteins gene gene2837 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14270 UM146_RS14275 UM146_13790 UM146_RS14275 2845198 2846481 + acyl-CoA thioesterase gene gene2838 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14275 UM146_RS14280 UM146_13795 UM146_RS14280 2846622 2848883 - hydratase gene gene2839 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14280 UM146_RS14285 UM146_13800 UM146_RS14285 2849066 2850499 - membrane protein gene gene2840 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14285 UM146_RS14290 UM146_13805 UM146_RS14290 2850575 2851606 - hypothetical protein gene gene2841 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14290 UM146_RS14295 UM146_13815 UM146_RS14295 2851810 2852763 + LysR family transcriptional regulator gene gene2842 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14295 UM146_RS14300 UM146_13820 UM146_RS14300 2852804 2853799 - 6-phosphogluconolactonase catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate gene gene2843 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14300 UM146_RS14305 UM146_13825 UM146_RS14305 2853954 2854772 + pyridoxal phosphate phosphatase gene gene2844 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14305 UM146_RS14310 UM146_13830 modC modC 2854773 2855831 - molybdenum import ATP-binding protein ModC Part of the ABC transporter complex modABC involved in molybdenum import gene gene2845 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14310 UM146_RS14315 UM146_13835 modB modB 2855834 2856523 - molybdate ABC transporter permease part of ModCBA molybdate transporter%3B member of ABC superfamily%3B inner membrane component%3B regulated by repressor protein ModE gene gene2846 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14315 UM146_RS14320 UM146_13840 modA modA 2856523 2857296 - molybdenum ABC transporter substrate-binding protein with ModCB is involved in the high-affinity transport of molybdate gene gene2847 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14320 UM146_RS14325 UM146_13845 UM146_RS14325 2857463 2857612 - multidrug efflux pump accessory protein AcrZ gene gene2848 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14325 UM146_RS14330 UM146_13850 UM146_RS14330 2857741 2858529 + transcriptional regulator ModE represses the modABCD operon and activates the moaABCD and napFDAGHBC operons gene gene2849 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14330 UM146_RS14335 UM146_RS14335 UM146_RS14335 2858523 2858669 + hypothetical protein gene gene2850 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14335 UM146_RS14340 UM146_13855 UM146_RS14340 2858597 2860069 + molybdenum ABC transporter ATP-binding protein contains 2 ATP-binding cassettes%3B involved in the transport of molybdenum gene gene2851 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14340 UM146_RS14345 UM146_13860 UM146_RS14345 2860331 2861347 + UDP-galactose-4-epimerase gene gene2852 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14345 UM146_RS14350 UM146_13865 UM146_RS14350 2861357 2862403 + galactose-1-phosphate uridylyltransferase catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P gene gene2853 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14350 UM146_RS14355 UM146_13870 UM146_RS14355 2862407 2863555 + galactokinase catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism gene gene2854 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14355 UM146_RS14360 UM146_13875 galM galM 2863549 2864589 + aldose 1-epimerase mutarotase%3B catalyzes the conversion of beta-galactose to the alpha-anomer%3B links the metabolism of lactose and galactose gene gene2855 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14360 UM146_RS14365 UM146_13880 gpmA gpmA 2864792 2865544 + 2%2C3-bisphosphoglycerate-dependent phosphoglycerate mutase 2%2C3-bisphosphoglycerate-dependent%3B catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate gene gene2856 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14365 UM146_RS14370 UM146_13885 UM146_RS14370 2865711 2866763 - phospho-2-dehydro-3-deoxyheptonate aldolase catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate%2C phenylalanine sensitive gene gene2857 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14370 UM146_RS14375 UM146_RS14375 UM146_RS14375 2866871 2866984 + glutamate decarboxylase gene gene2858 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14375 UM146_RS14380 UM146_13890 UM146_RS14380 2867079 2867459 + hypothetical protein gene gene2859 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14380 UM146_RS14385 UM146_13895 UM146_RS14385 2867573 2868514 + zinc transporter ZitB involved in zinc efflux across the cytoplasmic membrane gene gene2860 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14385 UM146_RS14390 UM146_13900 UM146_RS14390 2868511 2869230 - nicotinamide mononucleotide transporter involved in nicotinamide riboside transport gene gene2861 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14390 UM146_RS14395 UM146_13905 UM146_RS14395 2869268 2870311 - quinolinate synthase A 3 different subfamilies%3B catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate gene gene2862 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14395 UM146_RS14400 UM146_t23901 UM146_RS14400 2870589 2870664 - tRNA-OTHER tRNA gene2863 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14400 UM146_RS14405 UM146_t23903 UM146_RS14405 2870715 2870790 - tRNA-Lys tRNA gene2864 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14405 UM146_RS14410 UM146_RS14410 UM146_RS14410 2870955 2871745 - tol-pal system protein periplasmic protein that interacts with TolA%3B the tol-pal system is probably involved in maintaining cell envelope integrity gene gene2865 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14410 UM146_RS14415 UM146_13920 UM146_RS14415 2871755 2872276 - hypothetical protein gene gene2866 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14415 UM146_RS14420 UM146_13925 tolB tolB 2872311 2873603 - protein TolB forms dimers%3B may be involved in cell envelope integrity%3B interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA gene gene2867 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14420 UM146_RS14425 UM146_13930 tolA tolA 2873736 2874986 - cell envelope integrity/translocation protein TolA inner membrane component of 7 member Tol-Pal envelope-spanning complex%3B involved in maintaining cell envelope integrity%3B utilized by colicins and filamentous phages for import%3B interacts with TolB%2C Pal%2C and through TolB to various outer membrane porins gene gene2868 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14425 UM146_RS14430 UM146_13935 UM146_RS14430 2875051 2875479 - protein TolR membrane spanning protein in TolA-TolQ-TolR complex%3B involved in the tonB-independent uptake of group A colicins gene gene2869 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14430 UM146_RS14435 UM146_13940 UM146_RS14435 2875483 2876166 - colicin transporter membrane spanning protein in TolA-TolQ-TolR complex%3B involved in the tonB-independent uptake of group A colicins gene gene2870 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14435 UM146_RS14440 UM146_13945 UM146_RS14440 2876172 2876576 - acyl-CoA thioester hydrolase YbgC catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters%3B physiological role remains unknown%3B involved in phospholipid metabolism%3B part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components gene gene2871 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14440 UM146_RS14445 UM146_13950 UM146_RS14445 2876726 2877019 - cyd operon protein YbgE gene gene2872 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14445 UM146_RS14450 UM146_13955 UM146_RS14450 2877019 2877132 - cytochrome bd-I ubiquinol oxidase subunit X gene gene2873 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14450 UM146_RS14455 UM146_13960 UM146_RS14455 2877147 2878286 - cytochrome bd-I ubiquinol oxidase subunit 2 gene gene2874 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14455 UM146_RS14460 UM146_13965 UM146_RS14460 2878302 2879870 - cytochrome bd-I ubiquinol oxidase subunit 1 part of the aerobic respiratory chain%3B catalyzes the ubiquinol to ubiquinone gene gene2875 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14460 UM146_RS14465 UM146_13970 UM146_RS14465 2880974 2881246 - hypothetical protein gene gene2876 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14465 UM146_RS14470 UM146_13975 UM146_RS14470 2881200 2882315 - hypothetical protein gene gene2877 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14470 UM146_RS14475 UM146_13980 UM146_RS14475 2882555 2883424 - succinyl-CoA ligase subunit alpha Catalyzes the only substrate-level phosphorylation in the TCA cycle gene gene2878 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14475 UM146_RS14480 UM146_13985 sucC sucC 2883424 2884590 - succinyl-CoA ligase subunit beta catalyzes the interconversion of succinyl-CoA and succinate gene gene2879 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14480 UM146_RS14485 UM146_13990 UM146_RS14485 2884684 2885901 - dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex%3B catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA gene gene2880 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14485 UM146_RS14490 UM146_13995 UM146_RS14490 2885916 2888717 - 2-oxoglutarate dehydrogenase E1 component gene gene2881 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14490 UM146_RS14495 UM146_RS14495 UM146_RS14495 2888699 2888925 - hypothetical protein gene gene2882 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14495 UM146_RS14500 UM146_14000 sdhB sdhB 2889078 2889794 - succinate dehydrogenase iron-sulfur subunit part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers)%3B SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556%3B SdhC binds ubiquinone%3B oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol%3B the catalytic subunits are similar to fumarate reductase gene gene2883 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14500 UM146_RS14505 UM146_14005 sdhA sdhA 2889810 2891576 - succinate dehydrogenase flavoprotein subunit part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers)%3B SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556%3B SdhC binds ubiquinone%3B oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol gene gene2884 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14505 UM146_RS14510 UM146_14010 sdhD sdhD 2891576 2891923 - succinate dehydrogenase hydrophobic membrane anchor subunit gene gene2885 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14510 UM146_RS14515 UM146_14015 sdhC sdhC 2891917 2892321 - succinate dehydrogenase cytochrome b556 large membrane subunit gene gene2886 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14515 UM146_RS14520 UM146_RS14520 UM146_RS14520 2892842 2893027 - citrate synthase gene gene2887 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14520 UM146_RS14525 UM146_14020 gltA gltA 2893015 2894298 + citrate synthase type II enzyme%3B in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate%3B allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation%3B forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A%3B functions in TCA cycle%2C glyoxylate cycle and respiration%3B enzyme from Helicobacter pylori is not inhibited by NADH gene gene2888 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14525 UM146_RS14530 UM146_14025 UM146_RS14530 2894446 2894820 + gybgO gene gene2889 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14530 UM146_RS14535 UM146_14030 UM146_RS14535 2894972 2896018 + AbrB family transcriptional regulator gene gene2890 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14535 UM146_RS14540 UM146_14035 UM146_RS14540 2896015 2896806 - endonuclease VII 5-formyluracil/5-hydroxymethyluracil DNA glycosylase%3B involved in base excision repair of DNA damaged by oxidation or by mutagenic agents%3B acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines%3B has apurinic/apyrimidinic lyase activity gene gene2891 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14540 UM146_RS14545 UM146_14040 UM146_RS14545 2896842 2897576 - LamB/YcsF family protein gene gene2892 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14545 UM146_RS14550 UM146_14045 UM146_RS14550 2897566 2898498 - hypothetical protein gene gene2893 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14550 UM146_RS14555 UM146_14050 UM146_RS14555 2898492 2899148 - hypothetical protein gene gene2894 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14555 UM146_RS14560 UM146_14055 UM146_RS14560 2899171 2899914 - Nif3-like dinuclear metal center hexameric protein gene gene2895 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14560 UM146_RS14565 UM146_14060 UM146_RS14565 2900185 2901666 + peptide ABC transporter permease gene gene2896 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14565 UM146_RS14570 UM146_14065 UM146_RS14570 2901708 2903126 - deoxyribodipyrimidine photolyase UV-induced DNA repair%3B converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers%3B light dependent gene gene2897 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14570 UM146_RS14575 UM146_14070 UM146_RS14575 2903123 2903632 - hypothetical protein gene gene2898 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14575 UM146_RS14580 UM146_14075 UM146_RS14580 2903733 2903939 - hypothetical protein gene gene2899 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14580 UM146_RS14585 UM146_RS14585 kdpF kdpF 2904252 2904341 + protein KdpF one of the components of the high-affinity ATP-driven potassium transport (or KDP) system%2C which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions gene gene2900 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14585 UM146_RS14590 UM146_14080 UM146_RS14590 2904341 2906014 + potassium-transporting ATPase A chain catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions gene gene2901 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14590 UM146_RS14595 UM146_14085 UM146_RS14595 2906037 2908085 + potassium-transporting ATPase B chain One of the components of the high-affinity ATP-driven potassium transport (or KDP) system%2C which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions gene gene2902 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14595 UM146_RS14600 UM146_14090 UM146_RS14600 2908094 2908666 + potassium-transporting ATPase C chain One of the components of the high-affinity ATP-driven potassium transport (or KDP)system%2C which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex gene gene2903 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14600 UM146_RS14605 UM146_14095 UM146_RS14605 2908659 2911343 + two-component system sensor histidine kinase KdpD sensory histidine kinase in two-component regulatory system with KdpE%3B signal sensing protein gene gene2904 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14605 UM146_RS14610 UM146_14100 UM146_RS14610 2911340 2912017 + two-component system response regulator response regulator in two-component regulatory system with KdpD%3B regulates the kdp operon involved in potassium transport gene gene2905 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14610 UM146_RS14615 UM146_RS14615 UM146_RS14615 2912039 2912173 - hypothetical protein gene gene2906 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14615 UM146_RS14620 UM146_14105 UM146_RS14620 2912706 2914904 + ornithine decarboxylase gene gene2907 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14620 UM146_RS14625 UM146_14110 potE potE 2914901 2916220 + putrescine-ornithine antiporter catalyzes the uptake of putrescine via a proton symport mechanism%2C as well as the efflux of putrescine by a putrescine/ornithine antiport system gene gene2908 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14625 UM146_RS14630 UM146_14115 UM146_RS14630 2916276 2917916 - phosphoglucomutase catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate gene gene2909 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14630 UM146_RS14635 UM146_14120 UM146_RS14635 2917942 2918487 - negative modulator of initiation of replication negative modulator of the initiation of chromosome replication gene gene2910 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14635 UM146_RS14640 UM146_14125 UM146_RS14640 2918672 2919436 + acyl-CoA esterase gene gene2911 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14640 UM146_RS14645 UM146_14130 UM146_RS14645 2919576 2919869 + LexA-regulated protein%2C CopB family gene gene2912 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14645 UM146_RS14650 UM146_14135 UM146_RS14650 2920009 2920539 + flavodoxin-1 An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group gene gene2913 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14650 UM146_RS14655 UM146_RS14655 UM146_RS14655 2920529 2920783 - hypothetical protein gene gene2914 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14655 UM146_RS14660 UM146_RS14660 UM146_RS14660 2920749 2920835 + Fur leader peptide gene gene2915 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14660 UM146_RS14665 UM146_14140 fur fur 2920828 2921274 + ferric uptake regulation protein negatively regulates a number of operons that encode enzymes involved in iron transport%3B activated by manganese%3B forms a homodimer gene gene2916 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14665 UM146_RS14670 UM146_14145 UM146_RS14670 2921358 2921684 - hypothetical protein gene gene2917 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14670 UM146_RS14675 UM146_14150 chiP chiP 2921734 2923140 - chitoporin outer membrane porin involved in the transport of chitooligosaccharides gene gene2918 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14675 UM146_RS14680 UM146_RS14680 UM146_RS14680 2923398 2923586 + hypothetical protein gene gene2919 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14680 UM146_RS14685 UM146_14155 UM146_RS14685 2923589 2925253 - glutamine--tRNA ligase catalyzes a two-step reaction%2C first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA gene gene2920 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14685 UM146_RS14690 UM146_14160 UM146_RS14690 2925473 2926234 - DeoR family transcriptional regulator gene gene2921 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14690 UM146_RS14695 UM146_14165 pdxA pdxA 2926236 2927222 - 4-hydroxythreonine-4-phosphate dehydrogenase catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) gene gene2922 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14695 UM146_RS14700 UM146_14170 UM146_RS14700 2927215 2928450 - membrane protein gene gene2923 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14700 UM146_RS14705 UM146_14175 UM146_RS14705 2928620 2929777 + alcohol dehydrogenase gene gene2924 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14705 UM146_RS14710 UM146_14180 UM146_RS14710 2929781 2930668 + dihydrodipicolinate synthetase gene gene2925 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14710 UM146_RS14715 UM146_RS14715 UM146_RS14715 2930728 2931449 + hypothetical protein gene gene2926 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14715 UM146_RS14720 UM146_14195 UM146_RS14720 2931514 2932683 + glycosyl hydrolase gene gene2927 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14720 UM146_RS14725 UM146_14200 UM146_RS14725 2932680 2933150 + hypothetical protein gene gene2928 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14725 UM146_RS14730 UM146_14205 UM146_RS14730 2933164 2934444 + hypothetical protein gene gene2929 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14730 UM146_RS14735 UM146_14210 UM146_RS14735 2934533 2936479 - PTS N-acetylglucosamine transporter subunit IIABC phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene2930 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14735 UM146_RS14740 UM146_14215 nagB nagB 2936812 2937612 + glucosamine-6-phosphate deaminase catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate gene gene2931 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14740 UM146_RS14745 UM146_14220 nagA nagA 2937672 2938820 + N-acetylglucosamine-6-phosphate deacetylase catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate gene gene2932 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14745 UM146_RS14750 UM146_14225 UM146_RS14750 2938829 2940049 + N-acetylglucosamine repressor regulates the synthesis of glucosamine and N-acetylglucosamine by acting as a repressor of the nagEBACD operon and both a repressor and activator of the glmSU operon gene gene2933 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14750 UM146_RS14755 UM146_14230 UM146_RS14755 2940097 2940849 + ribonucleotide monophosphatase NagD gene gene2934 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14755 UM146_RS14760 UM146_14235 asnB asnB 2941105 2942769 + asparagine synthetase B [glutamine-hydrolyzing] functions in asparagine biosynthesis%3B converts glutamine%2C aspartate%2C ATP%2C and water to glutamate%2C asparagine%2C pyrophosphate and AMP gene gene2935 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14760 UM146_RS14765 UM146_t23905 UM146_RS14765 2943150 2943226 + tRNA-Met tRNA gene2936 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14765 UM146_RS14770 UM146_t23907 UM146_RS14770 2943237 2943321 + tRNA-Leu tRNA gene2937 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14770 UM146_RS14775 UM146_t23909 UM146_RS14775 2943345 2943419 + tRNA-Gln tRNA gene2938 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14775 UM146_RS14780 UM146_t23911 UM146_RS14780 2943454 2943528 + tRNA-Gln tRNA gene2939 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14780 UM146_RS14785 UM146_t23913 UM146_RS14785 2943544 2943620 + tRNA-Met tRNA gene2940 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14785 UM146_RS14790 UM146_t23915 UM146_RS14790 2943669 2943743 + tRNA-Gln tRNA gene2941 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14790 UM146_RS14795 UM146_t23917 UM146_RS14795 2943782 2943856 + tRNA-Gln tRNA gene2942 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14795 UM146_RS14800 UM146_14240 ubiF ubiF 2944011 2945186 - 2-octaprenyl-3-methyl-6-methoxy-1%2C4-benzoquinol hydroxylase catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1%2C4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1%2C4-benzoquinol%3B functions in the biosynthesis of ubiquinone or coenzyme Q gene gene2943 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14800 UM146_RS14805 UM146_14245 UM146_RS14805 2945332 2946756 + tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) gene gene2944 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14805 UM146_RS14810 UM146_14250 UM146_RS14810 2946909 2947949 + phoH-like protein gene gene2945 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14810 UM146_RS14815 UM146_14255 UM146_RS14815 2947946 2948413 + endoribonuclease YbeY gene gene2946 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14815 UM146_RS14820 UM146_14260 UM146_RS14820 2948503 2949381 + magnesium and cobalt efflux protein CorC involved in the transport of magnesium and cobalt ions gene gene2947 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14820 UM146_RS14825 UM146_14265 lnt lnt 2949406 2950947 + apolipoprotein N-acyltransferase Transfers the fatty acyl group on membrane lipoproteins gene gene2948 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14825 UM146_RS14830 UM146_14270 UM146_RS14830 2951074 2952951 - hypothetical protein gene gene2949 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14830 UM146_RS14835 UM146_14275 UM146_RS14835 2953405 2954313 + amino acid transporter gene gene2950 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14835 UM146_RS14840 UM146_14280 UM146_RS14840 2954483 2955223 + glutamate/aspartate ABC transporter permease GltJ with GltIKL is involved in the transport of glutamate and aspartate gene gene2951 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14840 UM146_RS14845 UM146_14285 UM146_RS14845 2955223 2955897 + glutamate ABC transporter permease with GltJLPS and GadC for glutamate and GltJLP%2C DctA and DcuAB for aspartate is involved in the transport of glutamate and aspartate gene gene2952 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14845 UM146_RS14850 UM146_14290 artP artP 2955897 2956622 + glutamate/aspartate transport ATP-binding protein GltL With ArtMQJI transports arginine across the inner membrane gene gene2953 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14850 UM146_RS14855 UM146_14295 rihA rihA 2956740 2957675 + pyrimidine-specific ribonucleoside hydrolase RihA Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil%2C respectively%3B pyrimidine-specific gene gene2954 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14855 UM146_RS14860 UM146_14300 UM146_RS14860 2957720 2958202 - hypothetical protein gene gene2955 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14860 UM146_RS14865 UM146_14305 leuS leuS 2958437 2961019 + leucyl-tRNA synthetase leucine--tRNA ligase%3B LeuRS%3B class-I aminoacyl-tRNA synthetase%3B charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA%3B due to the large number of codons that tRNA(Leu) recognizes%2C the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA%2C but instead recognition is dependent on a conserved discriminator base A37 and a long arm%3B an editing domain hydrolyzes misformed products%3B in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase gene gene2956 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14865 UM146_RS14870 UM146_14310 UM146_RS14870 2961034 2961615 + hypothetical protein rare lipoprotein B%3B involved in the assembly of LPS in the outer membrane gene gene2957 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14870 UM146_RS14875 UM146_14315 holA holA 2961615 2962646 + DNA polymerase III subunit delta required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA gene gene2958 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14875 UM146_RS14880 UM146_14320 UM146_RS14880 2962648 2963289 + nicotinate-nucleotide adenylyltransferase gene gene2959 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14880 UM146_RS14885 UM146_14325 UM146_RS14885 2963313 2963924 + alpha-ribazole phosphatase gene gene2960 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14885 UM146_RS14890 UM146_14330 UM146_RS14890 2964184 2964501 + ribosome silencing factor RsfS gene gene2961 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14890 UM146_RS14895 UM146_14335 UM146_RS14895 2964505 2964972 + ribosomal RNA large subunit methyltransferase H gene gene2962 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14895 UM146_RS14900 UM146_14340 UM146_RS14900 2965003 2966904 + penicillin-binding protein 2 gene gene2963 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14900 UM146_RS14905 UM146_14345 UM146_RS14905 2966907 2968019 + cell wall shape-determining protein gene gene2964 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14905 UM146_RS14910 UM146_14350 UM146_RS14910 2968030 2969118 + hypothetical protein septal ring protein%2C suppressor of prc%2C minor lipoprotein gene gene2965 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14910 UM146_RS14915 UM146_14355 UM146_RS14915 2969258 2970469 + D-alanyl-D-alanine carboxypeptidase penicillin-binding protein 5%3B removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors gene gene2966 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14915 UM146_RS14920 UM146_14360 UM146_RS14920 2970579 2970842 + hypothetical protein gene gene2967 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14920 UM146_RS14925 UM146_14365 UM146_RS14925 2970943 2971584 + octanoyltransferase lipoyl/octanoyltransferase%3B catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein gene gene2968 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14925 UM146_RS14930 UM146_RS14930 UM146_RS14930 2971636 2971785 - hypothetical protein gene gene2969 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14930 UM146_RS14935 UM146_14375 UM146_RS14935 2972404 2973369 + lipoyl synthase catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group gene gene2970 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14935 UM146_RS14940 UM146_14380 tatE tatE 2973469 2973672 - preprotein translocase subunit TatE TatE%3B similar to TatA and found in some proteobacteria%3B part of system that translocates proteins with a conserved twin arginine motif across the inner membrane%3B capable of translocating folded substrates typically those with bound cofactors%3B similar to a protein import system in thylakoid membranes gene gene2971 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14940 UM146_RS14945 UM146_14385 UM146_RS14945 2973801 2974589 - hydrolase gene gene2972 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14945 UM146_RS14950 UM146_14390 UM146_RS14950 2974685 2975068 + camphor resistance protein CrcB camphor resistance protein CrcB%3B may be involved in chromosome condensation%3B overexpression in Escherichia coli protects against decondensation by camphor%3B overexpressing the protein results in an increase in supercoiling gene gene2973 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14950 UM146_RS14955 UM146_14395 UM146_RS14955 2975121 2975330 - cold-shock protein CspE gene gene2974 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14955 UM146_RS14960 UM146_14400 pagP pagP 2975505 2976065 - lipid A palmitoyltransferase PagP catalyzes the transfer of palmitate to lipid A gene gene2975 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14960 UM146_RS14965 UM146_14405 dcuC dcuC 2976652 2978037 + anaerobic C4-dicarboxylate transporter DcuC responsible for the transport of C4-dicarboxylates during anaerobic growth gene gene2976 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14965 UM146_RS14970 UM146_14410 dpiA dpiA 2978078 2978758 - transcriptional regulator regulates the expression of citrate fermentation genes gene gene2977 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14970 UM146_RS14975 UM146_14415 dpiB dpiB 2978727 2980385 - sensor histidine kinase regulates the expression of citrate fermentation genes gene gene2978 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14975 UM146_RS14980 UM146_14420 UM146_RS14980 2980852 2981823 + [citrate [pro-3S]-lyase] ligase activates citrate lyase by acetylation of the gamma subunit gene gene2979 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14980 UM146_RS14985 UM146_14425 UM146_RS14985 2981838 2982134 + citrate lyase ACP gene gene2980 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14985 UM146_RS14990 UM146_14430 UM146_RS14990 2982131 2983039 + citrate lyase subunit beta citryl-ACP lyase%3B catalyzes the formation of acetate and oxaloacetate from citrate gene gene2981 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14990 UM146_RS14995 UM146_14435 UM146_RS14995 2983050 2984582 + citrate lyase subunit alpha citrate-ACP transferase%2C the alpha subunit catalyzes the formation of (3S)-citryl-CoA from acetyl-CoA and citrate gene gene2982 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS14995 UM146_RS15000 UM146_14440 citX citX 2984586 2985137 + apo-citrate lyase phosphoribosyl-dephospho-CoA transferase 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase%3B holo-citrate lyase synthase%3B CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate gene gene2983 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15000 UM146_RS15005 UM146_14445 citG citG 2985112 2985990 + 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA gene gene2984 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15005 UM146_RS15010 UM146_14450 UM146_RS15010 2986041 2987504 + citrate:succinate antiporter involved in the transport of citrate into the cell along with the export of succinate out of the cell gene gene2985 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15010 UM146_RS15015 UM146_14455 UM146_RS15015 2987618 2988424 + ribonuclease I gene gene2986 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15015 UM146_RS15020 UM146_14460 UM146_RS15020 2988654 2989064 + nucleoside diphosphate kinase regulator Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis%2C CTP for lipid synthesis%2C and GTP for protein elongation gene gene2987 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15020 UM146_RS15025 UM146_14465 UM146_RS15025 2989420 2989848 + universal stress protein G interacts with GroEL%3B is induced by starvation%2C heat shock and toxic agents gene gene2988 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15025 UM146_RS15030 UM146_14470 UM146_RS15030 2989969 2991534 - alkyl hydroperoxide reductase subunit F gene gene2989 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15030 UM146_RS15035 UM146_14475 UM146_RS15035 2991705 2992268 - alkyl hydroperoxide reductase subunit C with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols%3B AhpC reduced the hydroperoxide substrate gene gene2990 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15035 UM146_RS15040 UM146_14480 dsbG dsbG 2992640 2993386 + disulfide isomerase Involved in disulfide bond formation gene gene2991 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15040 UM146_RS15045 UM146_14485 UM146_RS15045 2993591 2994493 + LysR family transcriptional regulator gene gene2992 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15045 UM146_RS15050 UM146_14490 UM146_RS15050 2994640 2995860 + hypothetical protein gene gene2993 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15050 UM146_RS15055 UM146_14495 UM146_RS15055 2995845 2996462 + hypothetical protein gene gene2994 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15055 UM146_RS15060 UM146_14500 UM146_RS15060 2996463 2997623 - aminotransferase catalyzes the transfer of an amino moiety%3B preference for methionine followed by histidine and phenylalanine gene gene2995 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15060 UM146_RS15065 UM146_14505 UM146_RS15065 2997743 2998831 + oxidoreductase member of the iron-containing alcohol dehydrogenase family gene gene2996 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15065 UM146_RS15070 UM146_14510 UM146_RS15070 2998841 2999038 - hypothetical protein gene gene2997 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15070 UM146_RS15075 UM146_14515 UM146_RS15075 2999151 3001256 - carbon starvation protein gene gene2998 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15075 UM146_RS15080 UM146_14520 UM146_RS15080 3001437 3001850 - proofreading thioesterase EntH required for efficient enterobactin production gene gene2999 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15080 UM146_RS15085 UM146_14525 UM146_RS15085 3001853 3002599 - 2%2C3-dihydro-2%2C3-dihydroxybenzoate dehydrogenase catalyzes the formation of 2%2C3-dihydroxybenzoate from 2%2C3-dihydro-2%2C3-dihydroxybenzoate%3B involved in the biosynthesis of siderophores%2C enterobactin%2C bacillibactin or vibriobactin gene gene3000 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15085 UM146_RS15090 UM146_14530 UM146_RS15090 3002599 3003456 - enterobactin synthase component B 2%2C3 dihydro-2%2C3 dihydroxybenzoate synthase%3B catalyzes the formation of 2%2C3 dihydro-2%2C3 dihydroxybenzoate and pyruvate from isochorismate%3B with Ent DEF is involved in enterobactin synthesis gene gene3001 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15090 UM146_RS15095 UM146_14535 entE entE 3003470 3005080 - enterobactin synthase subunit E bifunctional 2%2C3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase%3B activates the carboxylate group of 2%2C3-dihydroxy-benzoate forming (2%2C3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2%2C3-dihydroxy-benzoate adenylate gene gene3002 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15095 UM146_RS15100 UM146_14540 UM146_RS15100 3005090 3006265 - isochorismate synthase gene gene3003 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15100 UM146_RS15105 UM146_14545 UM146_RS15105 3006454 3007410 + ferrienterobactin-binding periplasmic protein with FepCDG is involved in the transport of ferric enterobactin gene gene3004 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15105 UM146_RS15110 UM146_14550 UM146_RS15110 3007414 3008664 - enterobactin exporter EntS protein p43%3B inner membrane protein that exports enterobactin to the periplasmic space%3B member of the major facilitator superfamily (MFS) of transporters gene gene3005 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15110 UM146_RS15115 UM146_14555 UM146_RS15115 3008775 3009779 + iron-enterobactin transporter membrane protein with FepBCG is involved in the transport of ferric enterobactin gene gene3006 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15115 UM146_RS15120 UM146_14560 UM146_RS15120 3009776 3010768 + iron-enterobactin transporter permease with FepBCD is involved in the transport of ferric enterobactin gene gene3007 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15120 UM146_RS15125 UM146_14565 UM146_RS15125 3010765 3011580 + iron-enterobactin transporter ATP-binding protein with FepBDE is involved in the transport of ferric enterobactin gene gene3008 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15125 UM146_RS15130 UM146_14570 UM146_RS15130 3011577 3012710 - hypothetical protein in Salmonella is responsible for long O-antigen polymerization%3B may be part of the ferric enterobactin transport system%3B necessary for enetrobactin uptake gene gene3009 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15130 UM146_RS15135 UM146_14575 entF entF 3012926 3016807 - enterobactin synthase subunit F with EntB%2C EntD%2C and EntE forms the multienzyme complex enterobactin synthase%3B EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin gene gene3010 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15135 UM146_RS15140 UM146_14580 UM146_RS15140 3016804 3017022 - hypothetical protein gene gene3011 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15140 UM146_RS15145 UM146_14585 UM146_RS15145 3017025 3018227 - enterobactin/ferric enterobactin esterase gene gene3012 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15145 UM146_RS15150 UM146_14590 UM146_RS15150 3018470 3020710 + outer membrane receptor FepA Fep%3B Cbt%3B Cbr%3B FeuB%3B FepA%3B PfeA%3B IroN%3B BfeA%3B outer membrane receptor of ferric enterobactin and colicins B and D%3B interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space gene gene3013 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15150 UM146_RS15155 UM146_RS15155 UM146_RS15155 3020723 3020862 + hypothetical protein gene gene3014 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15155 UM146_RS15160 UM146_14595 UM146_RS15160 3020876 3021505 + 4'-phosphopantetheinyl transferase gene gene3015 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15160 UM146_RS15165 UM146_14600 UM146_RS15165 3021627 3021779 - protein HokE gene gene3016 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15165 UM146_RS15170 UM146_RS15170 UM146_RS15170 3021814 3022014 + hypothetical protein gene gene3017 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15170 UM146_RS15180 UM146_14610 UM146_RS15180 3022233 3023351 + carboxylate-amine ligase gene gene3019 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15180 UM146_RS15185 UM146_14615 UM146_RS15185 3023417 3023665 + membrane protein gene gene3020 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15185 UM146_RS15190 UM146_14620 UM146_RS15190 3023730 3024113 + hypothetical protein gene gene3021 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15190 UM146_RS15195 UM146_RS15195 UM146_RS15195 3024192 3024844 + dihydropteridine reductase catalyzes the reduction of nitroaromatic compounds such as nitrofurazone%2C quinones and the anti-tumor agent CB1954%3B NAD(P)H-dependent%3B oxygen insensitive gene gene3022 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15195 UM146_RS15200 UM146_14630 UM146_RS15200 3024952 3026199 + miniconductance mechanosensitive channel gene gene3023 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15200 UM146_RS15205 UM146_14635 UM146_RS15205 3026281 3027657 - aromatic amino acid transporter gene gene3024 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15205 UM146_RS15210 UM146_14640 UM146_RS15210 3027759 3030902 - cation transporter gene gene3025 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15210 UM146_RS15215 UM146_14645 UM146_RS15215 3030914 3032137 - metal RND transporter with CusA%2C CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver gene gene3026 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15215 UM146_RS15220 UM146_14650 UM146_RS15220 3032153 3032485 - cation transporter gene gene3027 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15220 UM146_RS15225 UM146_14655 UM146_RS15225 3032509 3033891 - cation transporter with CusA%2C CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver gene gene3028 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15225 UM146_RS15230 UM146_14660 UM146_RS15230 3034048 3034731 + two-component system response regulator response regulator in two-component regulatory system with CusS%3B regulates the copper efflux system gene gene3029 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15230 UM146_RS15235 UM146_14665 UM146_RS15235 3034721 3036163 + two-component system sensor histidine kinase gene gene3030 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15235 UM146_RS15240 UM146_14670 nfrB nfrB 3036313 3038550 + bacteriophage N4 adsorption protein B gene gene3031 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15240 UM146_RS15245 UM146_14675 UM146_RS15245 3038537 3041509 + hypothetical protein gene gene3032 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15245 UM146_RS15250 UM146_14680 UM146_RS15250 3041510 3042400 + hypothetical protein gene gene3033 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15250 UM146_RS15255 UM146_14685 UM146_RS15255 3043059 3044012 + protease gene gene3034 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15255 UM146_RS15260 UM146_14690 UM146_RS15260 3044256 3044912 + hypothetical protein gene gene3035 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15260 UM146_RS15265 UM146_14695 UM146_RS15265 3044967 3045323 - tail fiber assembly protein gene gene3036 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15265 UM146_RS15270 UM146_14700 UM146_RS15270 3045330 3045629 + integrase gene gene3037 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15270 UM146_RS15275 UM146_14705 UM146_RS15275 3045649 3045957 + integrase gene gene3038 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15275 UM146_RS15280 UM146_RS15280 UM146_RS15280 3046031 3046261 - hypothetical protein gene gene3039 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15280 UM146_RS15285 UM146_14710 UM146_RS15285 3046311 3047177 + bifunctional protein FolD gene gene3040 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15285 UM146_RS15290 UM146_14715 UM146_RS15290 3047179 3047391 + ribosome-associated protein gene gene3041 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15290 UM146_RS15295 UM146_14720 UM146_RS15295 3047499 3048020 + membrane protein gene gene3042 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15295 UM146_RS15300 UM146_14725 cysS cysS 3048056 3049441 - cysteine--tRNA ligase catalyzes a two-step reaction%3B charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA gene gene3043 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15300 UM146_RS15305 UM146_14730 UM146_RS15305 3049615 3050109 + peptidyl-prolyl cis-trans isomerase gene gene3044 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15305 UM146_RS15310 UM146_14735 UM146_RS15310 3050112 3050834 + UDP-2%2C3-diacylglucosamine hydrolase catalyzes the formation of 2%2C3%3Ddiacylglucosamine 1-phosphate from UDP-2%2C3%3Ddiacylglucosamine gene gene3045 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15310 UM146_RS15315 UM146_14740 UM146_RS15315 3050945 3051274 + hypothetical protein gene gene3046 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15315 UM146_RS15320 UM146_14745 purE purE 3051370 3051879 + N5-carboxyaminoimidazole ribonucleotide mutase catalyzes the formation of 4-carboxy-5-aminoimidazole ribonucleotide from N5-carboxyaminoimidazole ribonucleotide gene gene3047 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15320 UM146_RS15325 UM146_14750 UM146_RS15325 3051876 3052943 + phosphoribosylaminoimidazole carboxylase gene gene3048 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15325 UM146_RS15330 UM146_14755 UM146_RS15330 3053096 3053989 - carbamate kinase reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP gene gene3049 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15330 UM146_RS15335 UM146_14760 UM146_RS15335 3053986 3054801 - hypothetical protein gene gene3050 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15335 UM146_RS15340 UM146_14765 UM146_RS15340 3054812 3056071 - hypothetical protein gene gene3051 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15340 UM146_RS15345 UM146_14770 UM146_RS15345 3056081 3057748 - membrane protein multicopy suppressor of dominant negative ftsH mutations%3B putative acyl-CoA synthetase gene gene3052 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15345 UM146_RS15350 UM146_14775 UM146_RS15350 3058065 3059114 + ureidoglycolate dehydrogenase catalyzes the formation of oxalurate from ureidoglycolate gene gene3053 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15350 UM146_RS15355 UM146_14780 UM146_RS15355 3059136 3060371 + allantoate amidohydrolase gene gene3054 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15355 UM146_RS15360 UM146_14785 UM146_RS15360 3060382 3061167 + hypothetical protein gene gene3055 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15360 UM146_RS15365 UM146_14790 UM146_RS15365 3061296 3062441 - glycerate kinase gene gene3056 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15365 UM146_RS15370 UM146_14795 UM146_RS15370 3062463 3063764 - purine permease gene gene3057 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15370 UM146_RS15375 UM146_14800 UM146_RS15375 3063820 3065181 - allantoinase Plays a crucial role on both purine and pyrimidine metabolism gene gene3058 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15375 UM146_RS15380 UM146_14805 UM146_RS15380 3065241 3066695 - allantoin permease gene gene3059 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15380 UM146_RS15385 UM146_14810 UM146_RS15385 3066865 3067743 - 2-hydroxy-3-oxopropionate reductase NADH-dependent%3B catalyzed the reversible formation of glycerate from tartronate semialdehyde gene gene3060 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15385 UM146_RS15390 UM146_14815 UM146_RS15390 3067843 3068619 - hydroxypyruvate isomerase gene gene3061 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15390 UM146_RS15395 UM146_14820 UM146_RS15395 3068632 3070413 - glyoxylate carboligase catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate gene gene3062 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15395 UM146_RS15400 UM146_14825 UM146_RS15400 3070503 3071318 - transcriptional regulator regulates operons involved in the utilization of allantoin gene gene3063 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15400 UM146_RS15405 UM146_14830 UM146_RS15405 3071396 3071878 - ureidoglycolate lyase gene gene3064 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15405 UM146_RS15410 UM146_14835 UM146_RS15410 3072108 3073034 + HTH-type transcriptional activator AllS activator of the allDC-ylbA operon involved in allantoin utilization gene gene3065 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15410 UM146_RS15415 UM146_14840 UM146_RS15415 3073103 3074196 + tRNA 2-selenouridine synthase catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA gene gene3066 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15415 UM146_RS15420 UM146_14845 UM146_RS15420 3074255 3076669 - sugar ABC transporter permease gene gene3067 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15420 UM146_RS15425 UM146_14850 UM146_RS15425 3076666 3077352 - phosphonate ABC transporter ATP-binding protein gene gene3068 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15425 UM146_RS15430 UM146_14855 UM146_RS15430 3077323 3077946 + multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 gene gene3069 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15430 UM146_RS15435 UM146_14860 UM146_RS15435 3077975 3078745 + oxidoreductase gene gene3070 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15435 UM146_RS15440 UM146_14865 UM146_RS15440 3078806 3079660 + hypothetical protein gene gene3071 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15440 UM146_RS15445 UM146_14870 UM146_RS15445 3079723 3080502 - iron export permease FetB gene gene3072 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15445 UM146_RS15450 UM146_14875 UM146_RS15450 3080489 3081166 - iron export ATP-binding protein FetA gene gene3073 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15450 UM146_RS15455 UM146_14880 UM146_RS15455 3081312 3082229 + protease gene gene3074 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15455 UM146_RS15460 UM146_14885 UM146_RS15460 3082226 3082684 + membrane protein gene gene3075 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15460 UM146_RS15465 UM146_14890 UM146_RS15465 3082787 3083149 - hypothetical protein gene gene3076 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15465 UM146_RS15470 UM146_14895 UM146_RS15470 3083516 3084532 + adhesin gene gene3077 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15470 UM146_RS15475 UM146_14900 UM146_RS15475 3084618 3085040 + hypothetical protein gene gene3078 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15475 UM146_RS15480 UM146_14905 UM146_RS15480 3085037 3085240 + hypothetical protein gene gene3079 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15480 UM146_RS15485 UM146_14910 UM146_RS15485 3085244 3085651 - transcriptional regulator activator of copper-responsive regulon genes gene gene3080 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15485 UM146_RS15490 UM146_14915 UM146_RS15490 3085776 3087068 - amino acid permease gene gene3081 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15490 UM146_RS15495 UM146_14920 UM146_RS15495 3087071 3088003 - glutaminase catalyzes the formation of glutamate from glutamine gene gene3082 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15495 UM146_RS15500 UM146_14925 copA copA 3088265 3090769 + copper exporting ATPase gene gene3083 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15500 UM146_RS15505 UM146_14930 UM146_RS15505 3090827 3091168 - transcriptional regulator gene gene3084 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15505 UM146_RS15510 UM146_14935 UM146_RS15510 3091204 3091506 - hypothetical protein gene gene3085 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15510 UM146_RS15515 UM146_14940 UM146_RS15515 3091639 3092433 + hypothetical protein gene gene3086 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15515 UM146_RS15520 UM146_RS15520 UM146_RS15520 3092637 3093115 + hypothetical protein gene gene3087 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15520 UM146_RS15525 UM146_14950 UM146_RS15525 3093139 3093939 + hypothetical protein gene gene3088 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15525 UM146_RS15530 UM146_14955 UM146_RS15530 3093936 3094439 + hypothetical protein gene gene3089 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15530 UM146_RS15535 UM146_14960 ushA ushA 3094477 3096129 - 5'-nucleotidase catalyzes the degradation of periplasmic UDP-glucose to uridine%2C glucose-1-phosphate and inorganic phosphate%3B specific for uridine nucleotides gene gene3090 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15535 UM146_RS15540 UM146_14965 UM146_RS15540 3096347 3097567 + fosmidomycin resistance protein gene gene3091 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15540 UM146_RS15545 UM146_14970 UM146_RS15545 3097806 3099482 + cation:proton antiport protein YbaL%3B member of the CPA-2 family of antiporters%3B uncharacterized protein gene gene3092 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15545 UM146_RS15550 UM146_14975 UM146_RS15550 3099612 3100916 - inosine-guanosine kinase catalyzes the formation of inosine/guanosine monophosphate from inosine or guanosine and ATP gene gene3093 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15550 UM146_RS15555 UM146_14980 UM146_RS15555 3101068 3102027 + acetyl esterase gene gene3094 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15555 UM146_RS15560 UM146_14985 UM146_RS15560 3102024 3102986 - ferrochelatase gene gene3095 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15560 UM146_RS15565 UM146_14990 adk adk 3103118 3103762 - adenylate kinase essential enzyme that recycles AMP in active cells%3B converts ATP and AMP to two molecules of ADP gene gene3096 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15565 UM146_RS15570 UM146_14995 UM146_RS15570 3103943 3105817 - chaperone protein HtpG molecular chaperone gene gene3097 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15570 UM146_RS15575 UM146_15000 recR recR 3105927 3106532 - recombination protein RecR involved in a recombinational process of DNA repair%2C independent of the recBC complex gene gene3098 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15575 UM146_RS15580 UM146_15005 UM146_RS15580 3106532 3106861 - nucleoid-associated protein gene gene3099 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15580 UM146_RS15585 UM146_15010 UM146_RS15585 3106914 3108845 - DNA polymerase III subunit gamma/tau catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand%3B the tau chain serves as a scaffold to help in the dimerizaton of the alpha%2Cepsilon and theta core complex%3B the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA gene gene3100 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15585 UM146_RS15590 UM146_15015 UM146_RS15590 3108974 3109525 - adenine phosphoribosyltransferase catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis gene gene3101 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15590 UM146_RS15595 UM146_15020 UM146_RS15595 3109678 3110055 - membrane protein gene gene3102 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15595 UM146_RS15600 UM146_15025 UM146_RS15600 3110125 3110652 + primosomal replication protein N'' PriC%3B protein involved in DNA replication%3B part of the primosome%2C a protein complex required to restart stalled replication forks%3B binds the complex formed by PriA%2C PriB and DNA%3B PriC-dependent primosome requires a gap to restart DNA replication%3B stimulates Rep activity at stalled forks gene gene3103 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15600 UM146_RS15605 UM146_15030 UM146_RS15605 3110666 3110827 + hypothetical protein gene gene3104 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15605 UM146_RS15610 UM146_RS15610 UM146_RS15610 3110861 3111001 + hypothetical protein gene gene3105 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15610 UM146_RS15615 UM146_15035 UM146_RS15615 3111039 3114401 - hypothetical protein gene gene3106 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15615 UM146_RS15620 UM146_15040 UM146_RS15620 3114529 3115176 - transcriptional regulator regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine gene gene3107 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15620 UM146_RS15625 UM146_15045 UM146_RS15625 3115318 3116511 + MexE family multidrug efflux RND transporter periplasmic adaptor subunit with AcrD and TolC forms a transport system involved in resistance to a number of compounds including lipophilic antibiotics gene gene3108 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15625 UM146_RS15630 UM146_15050 UM146_RS15630 3116534 3119683 + multidrug efflux RND transporter permease subunit gene gene3109 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15630 UM146_RS15635 UM146_15055 UM146_RS15635 3120228 3120602 + Hha toxicity modulator TomB gene gene3110 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15635 UM146_RS15640 UM146_15060 UM146_RS15640 3120628 3120846 + hemolysin expression-modulating protein Hha with Hns involved in transcriptional regulation of hemolysin%3B non-specific DNA-binding protein which affects the production of multiple proteins gene gene3111 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15640 UM146_RS15645 UM146_15065 UM146_RS15645 3121020 3121571 + maltose O-acetyltransferase gene gene3112 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15645 UM146_RS15650 UM146_15070 UM146_RS15650 3121687 3122157 + hypothetical protein gene gene3113 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15650 UM146_RS15655 UM146_15075 UM146_RS15655 3122321 3123871 + hypothetical protein gene gene3114 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15655 UM146_RS15660 UM146_15080 UM146_RS15660 3123913 3124266 - DUF1428 domain-containing protein gene gene3115 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15660 UM146_RS15665 UM146_15085 UM146_RS15665 3124645 3124956 + methylated-DNA--protein-cysteine methyltransferase gene gene3116 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15665 UM146_RS15670 UM146_15090 UM146_RS15670 3124987 3125559 - hypothetical protein gene gene3117 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15670 UM146_RS15675 UM146_15095 UM146_RS15675 3125777 3126637 + acyl-CoA thioesterase 2 gene gene3118 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15675 UM146_RS15680 UM146_15100 UM146_RS15680 3126686 3127972 - ammonium transporter gene gene3119 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15680 UM146_RS15685 UM146_15105 UM146_RS15685 3128002 3128340 - nitrogen regulatory protein P-II 2 indirectly regulates nitrogen metabolism%3B at high nitrogen levels P-II prevents the phosphorylation of NR-I%2C the transcriptional activator of the glutamine synthetase gene (glnA)%3B at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA gene gene3120 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15685 UM146_RS15690 UM146_15110 UM146_RS15690 3128521 3130302 - multidrug ABC transporter ATP-binding protein gene gene3121 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15690 UM146_RS15695 UM146_15115 UM146_RS15695 3130295 3132067 - multidrug ABC transporter ATP-binding protein gene gene3122 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15695 UM146_RS15700 UM146_15120 UM146_RS15700 3132097 3132555 - transcriptional regulator gene gene3123 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15700 UM146_RS15705 UM146_15125 UM146_RS15705 3132707 3133528 - thiamin pyrimidine pyrophosphate hydrolase HMP-PP phosphatase%3B catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) gene gene3124 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15705 UM146_RS15710 UM146_15130 UM146_RS15710 3133628 3135328 + hypothetical protein gene gene3125 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15710 UM146_RS15715 UM146_15135 UM146_RS15715 3135393 3136088 + 7-cyano-7-deazaguanine synthase YbaX%3B catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0)%2C as one of the early reactions of quenosine biosynthesis%3B quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn%2C Asp%2C Tyr%2C and His gene gene3126 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15715 UM146_RS15720 UM146_15140 UM146_RS15720 3136140 3136538 - thioesterase gene gene3127 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15720 UM146_RS15725 UM146_15145 UM146_RS15725 3136644 3137015 - hypothetical protein gene gene3128 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15725 UM146_RS15730 UM146_15150 UM146_RS15730 3137166 3139037 - peptidyl-prolyl cis-trans isomerase gene gene3129 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15730 UM146_RS15735 UM146_15155 UM146_RS15735 3139229 3139501 - DNA-binding protein HU-beta histone-like DNA-binding protein gene gene3130 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15735 UM146_RS15740 UM146_15160 UM146_RS15740 3139710 3142064 - lon protease gene gene3131 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15740 UM146_RS15745 UM146_15165 clpX clpX 3142252 3143526 - ATP-dependent Clp protease ATP-binding subunit ClpX binds and unfolds substrates as part of the ClpXP protease gene gene3132 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15745 UM146_RS15750 UM146_15170 UM146_RS15750 3143652 3144275 - ATP-dependent Clp protease proteolytic subunit gene gene3133 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15750 UM146_RS15755 UM146_15175 UM146_RS15755 3144529 3145818 - trigger factor gene gene3134 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15755 UM146_RS15760 UM146_15180 UM146_RS15760 3145965 3146153 - hypothetical protein gene gene3135 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15760 UM146_RS15765 UM146_15185 UM146_RS15765 3146162 3146479 - protein BolA positive transcriptional regulator of morphogenetic pathway%3B controlling several genes involved in oxidative stress%2C acid stress%2C heat shock%2C osmotic shock%2C and carbon-starvation stress gene gene3136 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15765 UM146_RS15770 UM146_15190 UM146_RS15770 3146784 3147362 + hypothetical protein gene gene3137 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15770 UM146_RS15775 UM146_15195 ampG ampG 3147406 3148881 + AmpG family muropeptide MFS transporter in Escherichia coli this protein is a permease involved in peptidoglycan recycling%3B member of major facilitator superfamily%3B MFS%3B inner membrane protein gene gene3138 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15775 UM146_RS15780 UM146_15200 UM146_RS15780 3149340 3150287 + cytochrome bo(3) ubiquinol oxidase subunit 2 gene gene3139 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15780 UM146_RS15785 UM146_15205 UM146_RS15785 3150309 3152300 + cytochrome bo(3) ubiquinol oxidase subunit 1 gene gene3140 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15785 UM146_RS15790 UM146_15210 UM146_RS15790 3152290 3152904 + cytochrome O ubiquinol oxidase gene gene3141 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15790 UM146_RS15795 UM146_15215 UM146_RS15795 3152904 3153233 + cytochrome O ubiquinol oxidase gene gene3142 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15795 UM146_RS15800 UM146_15220 UM146_RS15800 3153245 3154135 + protoheme IX farnesyltransferase converts protoheme IX and farnesyl diphosphate to heme O gene gene3143 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15800 UM146_RS15805 UM146_15225 UM146_RS15805 3154284 3155648 + membrane protein gene gene3144 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15805 UM146_RS15810 UM146_15230 UM146_RS15810 3155776 3156267 - nucleotide-binding protein nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ%3B the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription gene gene3145 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15810 UM146_RS15815 UM146_15235 UM146_RS15815 3156435 3157346 + 2-dehydropantoate 2-reductase ketopantoate reductase%3B catalyzes the NADPH reduction of ketopantoate to pantoate%3B functions in pantothenate (vitamin B5) biosynthesis gene gene3146 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15815 UM146_RS15820 UM146_15240 UM146_RS15820 3157309 3157899 + oxidative-stress-resistance chaperone gene gene3147 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15820 UM146_RS15825 UM146_15245 UM146_RS15825 3157953 3159401 - tRNA sulfurtransferase catalyzes the conversion of uridine to 4-thiouridinine tRNA%3B also required for the synthesis of the thiazole moiety gene gene3148 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15825 UM146_RS15830 UM146_15250 UM146_RS15830 3159607 3159849 + exodeoxyribonuclease 7 small subunit catalyzes the bidirectional exonucleolytic cleavage of DNA gene gene3149 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15830 UM146_RS15835 UM146_15255 UM146_RS15835 3159849 3160748 + geranyltranstransferase gene gene3150 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15835 UM146_RS15840 UM146_15260 UM146_RS15840 3160773 3162635 + 1-deoxy-D-xylulose-5-phosphate synthase catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate gene gene3151 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15840 UM146_RS15845 UM146_15265 UM146_RS15845 3162690 3163664 + oxidoreductase gene gene3152 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15845 UM146_RS15850 UM146_15270 UM146_RS15850 3163718 3164236 - phosphatidylglycerophosphatase A hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate gene gene3153 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15850 UM146_RS15855 UM146_15275 UM146_RS15855 3164214 3165191 - thiamine-monophosphate kinase catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP gene gene3154 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15855 UM146_RS15860 UM146_15280 nusB nusB 3165269 3165688 - transcription antitermination protein NusB Regulates rRNA biosynthesis by transcriptional antitermination gene gene3155 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15860 UM146_RS15865 UM146_15285 ribH ribH 3165708 3166178 - 6%2C7-dimethyl-8-ribityllumazine synthase RibE%3B 6%2C7-diimethyl-8-ribityllumazine synthase%3B DMRL synthase%3B lumazine synthase%3B beta subunit of riboflavin synthase%3B condenses 5-amino-6-(1'-D)-ribityl-amino-2%2C4(1H%2C3H)-pyrimidinedione with L-3%2C4-dihydrohy-2-butanone-4-phosphate to generate 6%2C6-dimethyl-8-lumazine (DMRL)%3B riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12)%3B involved in the last steps of riboflavin biosynthesis%3B forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli%3B in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not gene gene3156 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15865 UM146_RS15870 UM146_15290 ribD ribD 3166267 3167370 - diaminohydroxyphosphoribosylaminopyrimidine deaminase riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway%3B catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2%2C5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil gene gene3157 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15870 UM146_RS15875 UM146_15295 UM146_RS15875 3167374 3167823 - NrdR family transcriptional regulator gene gene3158 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15875 UM146_RS15880 UM146_15300 UM146_RS15880 3167974 3168513 + hypothetical protein gene gene3159 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15880 UM146_RS15885 UM146_15305 UM146_RS15885 3168811 3169695 + ion channel protein Tsx receptor of phage T6 and colicin K%3B involved in the transfer of deoxyribo- and ribo-nucleotides across the outer membrane gene gene3160 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15885 UM146_RS15890 UM146_15310 UM146_RS15890 3169733 3170080 - hypothetical protein gene gene3161 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15890 UM146_RS15895 UM146_15315 UM146_RS15895 3170210 3171181 - protein translocase subunit SecF gene gene3162 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15895 UM146_RS15900 UM146_15320 secD secD 3171192 3173039 - preprotein translocase subunit SecD part of the preprotein secretory system%3B when complexed with proteins SecF and YajC%2C SecDFyajC stimulates the proton motive force-driven protein translocation%2C and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane gene gene3163 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15900 UM146_RS15905 UM146_15325 yajC yajC 3173067 3173399 - preprotein translocase subunit YajC member of preprotein translocase%3B forms a heterotrimer with SecD and SecF%3B links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex gene gene3164 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15905 UM146_RS15910 UM146_15330 tgt tgt 3173422 3174549 - queuine tRNA-ribosyltransferase Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp%2C -Asn%2C -His and -Tyr) gene gene3165 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15910 UM146_RS15915 UM146_15335 queA queA 3174604 3175674 - S-adenosylmethionine:tRNA ribosyltransferase-isomerase Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step gene gene3166 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15915 UM146_RS15920 UM146_15340 UM146_RS15920 3175893 3176474 + ACP phosphodiesterase Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP gene gene3167 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15920 UM146_RS15925 UM146_15345 UM146_RS15925 3176479 3178296 - maltodextrin glucosidase gene gene3168 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15925 UM146_RS15930 UM146_15350 proY proY 3178452 3179825 - proline-specific permease ProY cryptic permease that may be involved in the transport of proline across the inner membrane%3B in Salmonella typhimurium%2C the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation gene gene3169 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15930 UM146_RS15935 UM146_15355 UM146_RS15935 3179901 3181220 - branched-chain amino acid transporter 2 carrier protein BrnQ sodium:branched-chain amino acid symporter gene gene3170 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15935 UM146_RS15940 UM146_15360 phoR phoR 3181627 3182922 - phosphate regulon sensor protein membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB gene gene3171 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15940 UM146_RS15945 UM146_15365 UM146_RS15945 3182980 3183669 - two-component system response regulator two component response regulator for the phosphate regulon%3B PhoR phosphorylates PhoB gene gene3172 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15945 UM146_RS15950 UM146_15370 UM146_RS15950 3183859 3185061 + exonuclease subunit SbcD with SbcC cleaves DNA hairpin structure%2C also has 5' single-strand endonuclease activity gene gene3173 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15950 UM146_RS15955 UM146_15375 UM146_RS15955 3185058 3188201 + exonuclease subunit SbcC with SbcD cleaves DNA hairpin structures%3B also has 5' single-strand endonuclease activity gene gene3174 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15955 UM146_RS15960 UM146_15380 UM146_RS15960 3188327 3189511 + MFS transporter member of the major facilitator superfamily (MFS) of transporters%3B unknown function%3B may be associated with transport or processing of arabinose polymers gene gene3175 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15960 UM146_RS15965 UM146_15385 UM146_RS15965 3189780 3190688 - fructokinase catalyzes phosphorylation of fructose%3B cytosolic enzyme gene gene3176 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15965 UM146_RS15970 UM146_15390 UM146_RS15970 3190813 3191724 + recombination-associated protein RdgC Required for efficient pilin antigenic variation gene gene3177 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15970 UM146_RS15975 UM146_15395 UM146_RS15975 3191882 3192163 - hypothetical protein gene gene3178 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15975 UM146_RS15980 UM146_15410 UM146_RS15980 3192371 3192655 - hypothetical protein gene gene3179 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15980 UM146_RS15985 UM146_15415 UM146_RS15985 3192727 3193404 - hypothetical protein gene gene3180 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15985 UM146_RS15990 UM146_RS15990 UM146_RS15990 3193452 3193631 - hypothetical protein gene gene3181 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15990 UM146_RS15995 UM146_15420 UM146_RS15995 3193662 3193853 - hypothetical protein gene gene3182 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS15995 UM146_RS16000 UM146_15425 aroL aroL 3193903 3194427 - shikimate kinase type II enzyme similar to type I but differentially regulated and with a lower Km%3B catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis gene gene3183 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16000 UM146_RS16005 UM146_15430 UM146_RS16005 3194610 3195068 - hypothetical protein gene gene3184 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16005 UM146_RS16010 UM146_15435 UM146_RS16010 3195188 3195997 + pyrroline-5-carboxylate reductase catalyzes the formation of L-proline from pyrroline-5-carboxylate gene gene3185 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16010 UM146_RS16015 UM146_15440 adrA adrA 3196014 3197129 - diguanylate cyclase catalyzes the conversion of 2 GTP into c-di-GMP%3B adrA overexpression induces cellulose biosynthesis%2C cell adherence to abiotic surfaces and swimming and swarming motility%3B AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis gene gene3186 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16015 UM146_RS16020 UM146_15445 UM146_RS16020 3197231 3197551 - phosphate starvation-inducible protein PsiF gene gene3187 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16020 UM146_RS16025 UM146_15450 UM146_RS16025 3197670 3199085 - alkaline phosphatase gene gene3188 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16025 UM146_RS16030 UM146_15455 UM146_RS16030 3199186 3199446 - anti-adapter protein IraP RpoS stabilzer during Pi starvation%3B anti-adapter protein gene gene3189 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16030 UM146_RS16035 UM146_15470 UM146_RS16035 3199909 3201003 + D-alanine--D-alanine ligase A gene gene3190 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16035 UM146_RS16040 UM146_15475 UM146_RS16040 3201027 3201239 - DUF2754 domain-containing protein gene gene3191 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16040 UM146_RS16045 UM146_15480 UM146_RS16045 3201499 3201807 + hypothetical protein gene gene3192 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16045 UM146_RS16050 UM146_15485 UM146_RS16050 3201866 3202960 - hypothetical protein gene gene3193 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16050 UM146_RS16055 UM146_15490 UM146_RS16055 3202973 3204193 - peptide antibiotic transporter SbmA in Escherichia coli SbmA is involved in uptake of microcin J25%3B functions along with FhuA%2C TonB%2C and ExbB/D in this capacity%3B in Sinorhizobium meliloti%2C BacA is essential and required for symbiosis%3B defects appear to affect the cell envelope gene gene3194 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16055 UM146_RS16060 UM146_RS16060 UM146_RS16060 3204213 3204407 - hypothetical protein gene gene3195 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16060 UM146_RS16065 UM146_15495 UM146_RS16065 3204545 3205702 + beta-lactam-binding protein AmpH this protein has no known enzymatic function gene gene3196 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16065 UM146_RS16070 UM146_15500 UM146_RS16070 3205703 3206326 - transcriptional regulator gene gene3197 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16070 UM146_RS16075 UM146_RS16075 UM146_RS16075 3206412 3209399 - hypothetical protein gene gene3198 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16075 UM146_RS16080 UM146_15515 UM146_RS16080 3209925 3210899 + delta-aminolevulinic acid dehydratase gene gene3199 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16080 UM146_RS16085 UM146_15520 tauD tauD 3210939 3211790 - taurine dioxygenase catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide%3B non-heme iron oxidase%3B allows the use of taurine as an alternative sulfur source%3B forms homodimers gene gene3200 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16085 UM146_RS16090 UM146_15525 UM146_RS16090 3211787 3212614 - taurine ABC transporter permease gene gene3201 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16090 UM146_RS16095 UM146_15530 tauB tauB 3212611 3213378 - taurine import ATP-binding protein TauB Part of the ABC transporter complex tauABC involved in taurine import gene gene3202 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16095 UM146_RS16100 UM146_15535 tauA tauA 3213391 3214353 - taurine ABC transporter substrate-binding protein with TauB and TauC is responsible for taurine uptake. gene gene3203 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16100 UM146_RS16105 UM146_15540 UM146_RS16105 3214961 3215632 + hypothetical protein gene gene3204 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16105 UM146_RS16110 UM146_15545 UM146_RS16110 3215642 3216838 + membrane protein gene gene3205 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16110 UM146_RS16115 UM146_15550 UM146_RS16115 3216873 3217397 + acetyltransferase gene gene3206 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16115 UM146_RS16120 UM146_15555 UM146_RS16120 3217399 3218172 + membrane protein gene gene3207 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16120 UM146_RS16125 UM146_15560 UM146_RS16125 3218361 3218636 + transcriptional regulator formaldehyde-induced negative regulator of the frmRAB operon gene gene3208 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16125 UM146_RS16130 UM146_15565 UM146_RS16130 3218671 3219780 + S-(hydroxymethyl)glutathione dehydrogenase catalyzes the formation of S-formylglutathione from S-(hydroxymethyl)glutathione%3B also catalyzes the formation of aldehyde or ketone from alcohols gene gene3209 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16130 UM146_RS16135 UM146_15570 UM146_RS16135 3219873 3220706 + S-formylglutathione hydrolase FrmB gene gene3210 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16135 UM146_RS16140 UM146_15575 UM146_RS16140 3220932 3221471 - DUF2058 domain-containing protein gene gene3211 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16140 UM146_RS16145 UM146_15580 lacI lacI 3221796 3222755 + lac repressor transcriptional repressor of lac operon%3B forms a homotetramer as a dimer of dimers%3B binds specific sites in lac operon resulting in DNA looping between the operators%3B binds allolactose as inducer gene gene3212 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16145 UM146_RS16150 UM146_15585 lacZ lacZ 3222878 3225952 + beta-galactosidase forms a homotetramer%3B hydrolyzes lactose disaccharide to galactose and glucose%3B converts lactose to allolactose which is the natural inducer of the lac operon gene gene3213 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16150 UM146_RS16155 UM146_15590 lacY lacY 3226004 3227257 + lactose permease lactose/proton symporter%3B mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides%3B member of major facilitator superfamily%3B functions as a monomer with 12 transmembrane segments gene gene3214 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16155 UM146_RS16160 UM146_15595 lacA lacA 3227323 3227934 + galactoside O-acetyltransferase transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides%3B exact physiological role is unknown gene gene3215 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16160 UM146_RS16165 UM146_15600 UM146_RS16165 3228055 3229338 - cytosine deaminase Catalyzes the deamination of cytosine to uracil and ammonia gene gene3216 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16165 UM146_RS16170 UM146_15605 codB codB 3229328 3230587 - cytosine permease gene gene3217 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16170 UM146_RS16175 UM146_15610 prpE prpE 3230912 3232798 - propionate--CoA ligase catalyzes the formation of propionyl-CoA using propionate as a substrate%3B PrpE from Ralstonia solanacearum can produce acetyl-%2C propionyl-%2C butyryl- and acrylyl-coenzyme A%2C and Salmonella enterica produces propionyl- and butyryl-coenzyme A%3B not expressed in Escherichia coli when grown on propionate/minimal media%3B ATP-dependent gene gene3218 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16175 UM146_RS16180 UM146_15615 prpD prpD 3232838 3234289 - 2-methylcitrate dehydratase functions in propionate metabolism%3B involved in isomerization of (2S%2C3S)-methylcitrate to (2R%2C3S)-methylisocitrate%3B also encodes minor aconitase or dehydratase activity%3B aconitase C gene gene3219 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16180 UM146_RS16185 UM146_15620 UM146_RS16185 3234323 3235491 - methylcitrate synthase catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate%3B also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity gene gene3220 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16185 UM146_RS16190 UM146_15625 prpB prpB 3235536 3236426 - 2-methylisocitrate lyase catalyzes the formation of pyruvate and succinate from 2-methylisocitrate gene gene3221 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16190 UM146_RS16195 UM146_RS16195 UM146_RS16195 3236665 3237003 + hypothetical protein gene gene3222 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16195 UM146_RS16200 UM146_RS16200 UM146_RS16200 3237022 3238251 + propionate catabolism operon regulatory protein PrpR sigma-54 dependent activator family protein%3B activates the prpBCDE operon gene gene3223 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16200 UM146_RS16205 UM146_15640 UM146_RS16205 3238352 3238627 - hypothetical protein gene gene3224 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16205 UM146_RS16210 UM146_15645 UM146_RS16210 3238813 3239445 + membrane protein gene gene3225 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16210 UM146_RS16215 UM146_15650 UM146_RS16215 3239462 3239707 - hypothetical protein gene gene3226 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16215 UM146_RS16220 UM146_15655 UM146_RS16220 3240329 3241378 - zinc-binding dehydrogenase gene gene3227 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16220 UM146_RS16225 UM146_15660 UM146_RS16225 3241465 3242421 - sugar ABC transporter permease gene gene3228 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16225 UM146_RS16230 UM146_15665 UM146_RS16230 3242418 3243389 - sugar ABC transporter permease gene gene3229 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16230 UM146_RS16235 UM146_15670 UM146_RS16235 3243382 3244866 - sugar ABC transporter ATP-binding protein gene gene3230 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16235 UM146_RS16240 UM146_15675 UM146_RS16240 3244915 3245898 - LacI family transcriptional regulator gene gene3231 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16240 UM146_RS16245 UM146_15680 UM146_RS16245 3246152 3246562 - hypothetical protein gene gene3232 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16245 UM146_RS16250 UM146_15685 UM146_RS16250 3246860 3248242 - deaminase metallo-dependent hydrolase superfamily%3B deaminase with metallo-dependent hydrolase domain gene gene3233 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16250 UM146_RS16255 UM146_15690 UM146_RS16255 3248252 3249202 - carbamate kinase gene gene3234 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16255 UM146_RS16260 UM146_15695 UM146_RS16260 3249356 3250774 - hypothetical protein gene gene3235 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16260 UM146_RS16265 UM146_15700 UM146_RS16265 3250774 3252321 - hypothetical protein gene gene3236 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16265 UM146_RS16270 UM146_15705 UM146_RS16270 3252311 3253174 - hypothetical protein gene gene3237 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16270 UM146_RS16275 UM146_15710 UM146_RS16275 3253214 3253819 - hypothetical protein gene gene3238 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16275 UM146_RS16280 UM146_15715 UM146_RS16280 3254077 3254574 + membrane protein gene gene3239 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16280 UM146_RS16285 UM146_15720 UM146_RS16285 3254666 3255559 + LysR family transcriptional regulator gene gene3240 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16285 UM146_RS16290 UM146_15725 UM146_RS16290 3255639 3256727 - cyclic di-GMP phosphodiesterase gene gene3241 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16290 UM146_RS16295 UM146_RS16295 UM146_RS16295 3257048 3257236 + hypothetical protein gene gene3242 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16295 UM146_RS16300 UM146_15730 UM146_RS16300 3257605 3259638 - choline transporter BetT proton-motive-force-driven choline transporter gene gene3243 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16300 UM146_RS16305 UM146_15735 UM146_RS16305 3259767 3260354 + transcriptional regulator HTH-type%3B bet1%3B Repressor involved in choline regulation of the bet genes gene gene3244 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16305 UM146_RS16310 UM146_15740 UM146_RS16310 3260368 3261840 + NAD/NADP-dependent betaine aldehyde dehydrogenase gene gene3245 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16310 UM146_RS16315 UM146_15745 UM146_RS16315 3261854 3263542 + oxygen-dependent choline dehydrogenase catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine gene gene3246 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16315 UM146_RS16320 UM146_15750 UM146_RS16320 3263567 3263794 - hypothetical protein gene gene3247 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16320 UM146_RS16325 UM146_15755 UM146_RS16325 3264611 3265174 + DNA recombinase gene gene3248 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16325 UM146_RS16330 UM146_15760 UM146_RS16330 3265503 3266297 + LuxR family transcriptional regulator gene gene3249 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16330 UM146_RS16335 UM146_RS16335 UM146_RS16335 3266661 3267212 + hypothetical protein gene gene3250 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16335 UM146_RS16340 UM146_15770 UM146_RS16340 3267254 3269551 + autotransporter gene gene3251 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16340 UM146_RS16345 UM146_15775 UM146_RS16345 3269735 3270402 + hypothetical protein gene gene3252 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16345 UM146_RS16350 UM146_RS16350 UM146_RS16350 3270449 3270571 + universal stress protein gene gene3253 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16350 UM146_RS16355 UM146_15780 UM146_RS16355 3270645 3271340 - hypothetical protein gene gene3254 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16355 UM146_RS16360 UM146_15785 UM146_RS16360 3271333 3272760 - amino acid dehydrogenase gene gene3255 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16360 UM146_RS16365 UM146_15790 UM146_RS16365 3272771 3273490 - hypothetical protein gene gene3256 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16365 UM146_RS16370 UM146_15795 UM146_RS16370 3274017 3274871 - AraC family transcriptional regulator gene gene3257 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16370 UM146_RS16375 UM146_15800 UM146_RS16375 3275098 3276423 + pyridine nucleotide-disulfide oxidoreductase Involved in disulfide oxidoreductase activity and electron transport gene gene3258 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16375 UM146_RS16380 UM146_15805 UM146_RS16380 3276532 3276768 + hypothetical protein gene gene3259 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16380 UM146_RS16385 UM146_15810 UM146_RS16385 3276780 3277373 + membrane protein gene gene3260 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16385 UM146_RS16390 UM146_15815 UM146_RS16390 3277533 3278402 - aldo/keto reductase gene gene3261 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16390 UM146_RS16395 UM146_15820 UM146_RS16395 3278650 3279507 + transcriptional regulator gene gene3262 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16395 UM146_RS16400 UM146_15825 UM146_RS16400 3279632 3283882 - hypothetical protein gene gene3263 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16400 UM146_RS16405 UM146_15830 UM146_RS16405 3284448 3285299 + 2%2C5-diketo-D-gluconic acid reductase gene gene3264 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16405 UM146_RS16410 UM146_15835 UM146_RS16410 3285326 3286315 + aldo/keto reductase gene gene3265 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16410 UM146_RS16415 UM146_15840 UM146_RS16415 3286346 3287239 - transcriptional regulator gene gene3266 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16415 UM146_RS16420 UM146_15845 UM146_RS16420 3287439 3288365 - transcriptional regulator gene gene3267 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16420 UM146_RS16425 UM146_15850 UM146_RS16425 3288522 3289442 + alpha/beta hydrolase gene gene3268 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16425 UM146_RS16430 UM146_15855 UM146_RS16430 3289614 3290756 + NADH-dependent flavin oxidoreductase gene gene3269 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16430 UM146_RS16435 UM146_15860 UM146_RS16435 3291230 3291331 + membrane protein gene gene3270 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16435 UM146_RS16440 UM146_15865 UM146_RS16440 3291696 3291959 + 50S ribosomal protein L31 type B gene gene3271 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16440 UM146_RS16445 UM146_15870 rpmJ rpmJ 3291959 3292099 + 50S ribosomal protein L36 smallest protein in the large subunit%3B similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc%3B the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion%3B the proteins in this group do not have the motif gene gene3272 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16445 UM146_RS16450 UM146_15875 UM146_RS16450 3293183 3293725 + LuxR family transcriptional regulator gene gene3273 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16450 UM146_RS16455 UM146_15880 UM146_RS16455 3293768 3294385 + common pilus major fimbrillin subunit EcpA gene gene3274 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16455 UM146_RS16460 UM146_15885 UM146_RS16460 3294442 3295110 + fimbrial chaperone EcpB gene gene3275 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16460 UM146_RS16465 UM146_15890 UM146_RS16465 3295136 3297661 + usher protein EcpC gene gene3276 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16465 UM146_RS16470 UM146_15895 UM146_RS16470 3297651 3299294 + fimbria adhesin EcpD gene gene3277 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16470 UM146_RS16475 UM146_15900 UM146_RS16475 3299263 3299973 + fimbrial chaperone EcpE gene gene3278 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16475 UM146_RS16480 UM146_15905 UM146_RS16480 3300280 3300609 + hypothetical protein gene gene3279 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16480 UM146_RS16485 UM146_15910 UM146_RS16485 3300858 3301472 - membrane protein gene gene3280 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16485 UM146_RS16490 UM146_15915 UM146_RS16490 3301687 3301872 - hypothetical protein gene gene3281 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16490 UM146_RS16495 UM146_RS16495 UM146_RS16495 3302296 3302520 - transposase gene gene3282 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16495 UM146_RS16510 UM146_15925 UM146_RS16510 3302774 3302989 - transposase gene gene3284 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16510 UM146_RS16515 UM146_15930 UM146_RS16515 3303582 3307712 + peptidase gene gene3285 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16515 UM146_RS16520 UM146_15935 UM146_RS16520 3307838 3308362 + transcriptional regulator gene gene3286 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16520 UM146_RS16525 UM146_15940 UM146_RS16525 3308797 3309135 - integrase gene gene3287 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16525 UM146_RS16530 UM146_t23923 UM146_RS16530 3309290 3309365 - tRNA-Thr tRNA gene3288 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16530 UM146_RS16535 UM146_RS16535 UM146_RS16535 3309604 3310517 + hypothetical protein gene gene3289 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16535 UM146_RS16540 UM146_15960 UM146_RS16540 3311024 3311488 - XRE family transcriptional regulator gene gene3290 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16540 UM146_RS16545 UM146_15965 UM146_RS16545 3311727 3312224 + membrane protein gene gene3291 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16545 UM146_RS16550 UM146_15970 UM146_RS16550 3312382 3312939 - resolvase gene gene3292 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16550 UM146_RS16555 UM146_15975 UM146_RS16555 3313176 3315440 + hypothetical protein gene gene3293 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16555 UM146_RS16560 UM146_15980 UM146_RS16560 3315437 3317275 + ATPase AAA gene gene3294 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16560 UM146_RS16565 UM146_15985 UM146_RS16565 3317439 3317771 + hypothetical protein gene gene3295 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16565 UM146_RS16570 UM146_15990 UM146_RS16570 3318041 3319883 + sporadically distributed protein%2C TIGR04141 family gene gene3296 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16570 UM146_RS16575 UM146_15995 UM146_RS16575 3319978 3321909 - integrase gene gene3297 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16575 UM146_RS16580 UM146_t23925 UM146_RS16580 3321997 3322072 - tRNA-Thr tRNA gene3298 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16580 UM146_RS16585 UM146_16000 UM146_RS16585 3322187 3323440 - gamma-glutamyl phosphate reductase gene gene3299 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16585 UM146_RS16590 UM146_16005 UM146_RS16590 3323452 3324555 - glutamate 5-kinase gene gene3300 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16590 UM146_RS16595 UM146_16010 UM146_RS16595 3324844 3325899 + phosphoporin protein E gene gene3301 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16595 UM146_RS16600 UM146_16015 UM146_RS16600 3326009 3326410 - sigma factor-binding protein Crl involved in the expression of csgBA which is involved in curli formation%3B interacts with sigmaS gene gene3302 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16600 UM146_RS16605 UM146_16020 frsA frsA 3326468 3327712 - esterase forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc%3B FrsA may promote fermentation gene gene3303 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16605 UM146_RS16610 UM146_16025 UM146_RS16610 3327804 3328262 - xanthine phosphoribosyltransferase catalyzes the conversion of guanine%2C xanthine and%2C to a lesser extent%2C hypoxanthine to GMP%2C XMP and IMP%2C respectively gene gene3304 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16610 UM146_RS16615 UM146_16030 UM146_RS16615 3328523 3329980 + aminoacyl-histidine dipeptidase catalyzes the hydrolysis of Xaa-His dipeptides gene gene3305 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16615 UM146_RS16620 UM146_16035 prfH prfH 3330037 3330651 - peptide chain release factor similar to release factor 1 and 2 gene gene3306 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16620 UM146_RS16625 UM146_16040 UM146_RS16625 3330648 3331787 - hypothetical protein mutations in this gene result in a compromised ability for drug-inducible mexXY expression%3B expression is inducible by the same ribosome-targeting agents that induce mexXY gene gene3307 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16625 UM146_RS16630 UM146_16045 UM146_RS16630 3331977 3332351 - acyltransferase gene gene3308 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16630 UM146_RS16635 UM146_16050 UM146_RS16635 3332439 3332837 - toxin YafO YafO overproduction induces toxicity%3B it is believed to be the toxin of a toxin-antitoxin pair%3B unknown function gene gene3309 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16635 UM146_RS16640 UM146_16055 UM146_RS16640 3332840 3333133 - antitoxin YafN gene gene3310 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16640 UM146_RS16645 UM146_16060 UM146_RS16645 3333185 3334240 - DNA polymerase IV involved in translesion DNA polymerization with beta clamp of polymerase III%3B belongs to Y family of polymerases%3B does not contain proofreading function gene gene3311 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16645 UM146_RS16650 UM146_16065 UM146_RS16650 3334311 3335096 - hypothetical protein gene gene3312 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16650 UM146_RS16655 UM146_16070 UM146_RS16655 3335041 3336780 + flagellar biosynthesis protein FlhA gene gene3313 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16655 UM146_RS16660 UM146_16075 UM146_RS16660 3337099 3337596 - hypothetical protein gene gene3314 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16660 UM146_RS16665 UM146_16080 UM146_RS16665 3337772 3338521 - hypothetical protein gene gene3315 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16665 UM146_RS16670 UM146_16085 UM146_RS16670 3338833 3339573 + transpeptidase gene gene3316 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16670 UM146_RS16675 UM146_16090 UM146_RS16675 3339544 3340311 - glutamine amidotransferase gene gene3317 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16675 UM146_RS16680 UM146_16095 gmhA gmhA 3340516 3341094 - phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate gene gene3318 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16680 UM146_RS16685 UM146_16100 fadE fadE 3341334 3343778 + acyl-CoA dehydrogenase functions in fatty acid oxidation%3B converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA gene gene3319 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16685 UM146_RS16690 UM146_16105 UM146_RS16690 3343821 3344267 - hypothetical protein inactivates vertebrate C-type lysozyme gene gene3320 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16690 UM146_RS16695 UM146_16110 UM146_RS16695 3344448 3345218 + hypothetical protein NAD(P)-binding gene gene3321 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16695 UM146_RS16700 UM146_16115 UM146_RS16700 3345489 3345977 - conjugative transfer protein gene gene3322 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16700 UM146_RS16705 UM146_16120 UM146_RS16705 3346071 3346574 - hypothetical protein gene gene3323 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16705 UM146_RS16710 UM146_16125 UM146_RS16710 3346803 3347288 - transposase gene gene3324 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16710 UM146_RS16715 UM146_16130 UM146_RS16715 3347388 3347567 - hypothetical protein gene gene3325 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16715 UM146_RS16720 UM146_16135 UM146_RS16720 3347825 3348115 - hypothetical protein gene gene3326 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16720 UM146_RS16725 UM146_RS16725 UM146_RS16725 3348090 3349529 - peptidase C39 gene gene3327 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16725 UM146_RS16730 UM146_16145 UM146_RS16730 3349522 3350568 - hypothetical protein gene gene3328 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16730 UM146_RS16735 UM146_16150 UM146_RS16735 3350675 3352657 - type IV secretion protein Rhs gene gene3329 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16735 UM146_RS16740 UM146_16155 UM146_RS16740 3352673 3352792 - hypothetical protein gene gene3330 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16740 UM146_RS16745 UM146_16160 UM146_RS16745 3352878 3353396 - hypothetical protein gene gene3331 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16745 UM146_RS16750 UM146_16165 UM146_RS16750 3354102 3354605 + hypothetical protein gene gene3332 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16750 UM146_RS16755 UM146_16170 UM146_RS16755 3354628 3356112 + type VI secretion protein gene gene3333 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16755 UM146_RS16760 UM146_16175 UM146_RS16760 3356117 3356542 + type VI secretion protein gene gene3334 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16760 UM146_RS16765 UM146_16180 UM146_RS16765 3356548 3358389 + type VI secretion protein gene gene3335 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16765 UM146_RS16770 UM146_16185 UM146_RS16770 3358353 3359402 + type VI secretion protein gene gene3336 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16770 UM146_RS16775 UM146_16190 UM146_RS16775 3359419 3360699 + type VI secretion protein gene gene3337 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16775 UM146_RS16780 UM146_16195 UM146_RS16780 3360696 3361220 + hypothetical protein gene gene3338 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16780 UM146_RS16785 UM146_16200 UM146_RS16785 3361223 3362569 + hypothetical protein gene gene3339 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16785 UM146_RS16790 UM146_16205 UM146_RS16790 3362583 3363338 + membrane protein gene gene3340 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16790 UM146_RS16795 UM146_16210 UM146_RS16795 3363348 3366107 + ATP-dependent Clp protease ClpV gene gene3341 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16795 UM146_RS16800 UM146_16215 UM146_RS16800 3366104 3366847 + type VI secretion protein gene gene3342 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16800 UM146_RS16805 UM146_16220 UM146_RS16805 3366852 3368294 + type VI secretion protein gene gene3343 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16805 UM146_RS16810 UM146_16225 UM146_RS16810 3368314 3371841 + type VI secretion protein IcmF gene gene3344 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16810 UM146_RS16815 UM146_RS16815 UM146_RS16815 3371852 3373210 + hypothetical protein gene gene3345 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16815 UM146_RS16820 UM146_16240 UM146_RS16820 3373228 3373707 + type VI secretion system protein gene gene3346 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16820 UM146_RS16825 UM146_16245 UM146_RS16825 3374047 3374832 - hypothetical protein gene gene3347 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16825 UM146_RS16830 UM146_t23927 UM146_RS16830 3375161 3375237 - tRNA-Asp tRNA gene3348 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16830 UM146_RS16835 UM146_16250 UM146_RS16835 3375370 3376110 - DNA polymerase III subunit epsilon 3'-5' exonuclease of DNA polymerase III gene gene3349 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16835 UM146_RS16840 UM146_16255 UM146_RS16840 3376166 3376633 + ribonuclease HI%2C degrades RNA of DNA-RNA hybrids gene gene3350 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16840 UM146_RS16845 UM146_16260 UM146_RS16845 3376630 3377352 - hypothetical protein gene gene3351 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16845 UM146_RS16850 UM146_16265 UM146_RS16850 3377386 3378141 + hydroxyacylglutathione hydrolase catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione%3B plays an important role in cellular detoxification using glutathione gene gene3352 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16850 UM146_RS16855 UM146_RS16855 mltD mltD 3378213 3379570 + lytic murein transglycosylase catalyzes the cleavage of the beta-1%2C4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues%3B may play a role in recycling muropeptides during cell division and/or cell elongation%3B in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall gene gene3353 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16855 UM146_RS16860 UM146_16280 UM146_RS16860 3379617 3380387 - S-adenosyl-L-methionine (SAM)-dependent methyltransferase PhcB gene gene3354 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16860 UM146_RS16865 UM146_16285 UM146_RS16865 3380465 3381265 - endo/exonuclease/phosphatase gene gene3355 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16865 UM146_RS16870 UM146_16290 UM146_RS16870 3381506 3382420 + LysR family transcriptional regulator gene gene3356 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16870 UM146_RS16875 UM146_16295 dkgB dkgB 3382417 3383220 - 2%2C5-diketo-D-gluconate reductase B catalyzes the reduction of 2%2C5-diketo-D-gluconic acid to 2-keto-L-gulonic acid gene gene3357 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16875 UM146_RS16880 UM146_t23929 UM146_RS16880 3383382 3383458 - tRNA-Asp tRNA gene3358 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16880 UM146_RS16885 UM146_r23995 UM146_RS16885 3383512 3383627 - 5S ribosomal RNA rRNA gene3359 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16885 UM146_RS16890 UM146_r24021 UM146_RS16890 3383711 3386640 - 23S ribosomal RNA rRNA gene3360 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16890 UM146_RS16895 UM146_t23931 UM146_RS16895 3386815 3386890 - tRNA-Ala tRNA gene3361 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16895 UM146_RS16900 UM146_t23933 UM146_RS16900 3386933 3387009 - tRNA-Ile tRNA gene3362 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16900 UM146_RS16905 UM146_r24007 UM146_RS16905 3387068 3388621 - 16S ribosomal RNA rRNA gene3363 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16905 UM146_RS16910 UM146_16305 UM146_RS16910 3389092 3389646 + hypothetical protein gene gene3364 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16910 UM146_RS16915 UM146_16310 UM146_RS16915 3389622 3389879 - hypothetical protein gene gene3365 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16915 UM146_RS16920 UM146_16315 UM146_RS16920 3389876 3390694 - shikimate dehydrogenase (NADP+) gene gene3366 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16920 UM146_RS16925 UM146_16320 UM146_RS16925 3390699 3391271 - threonylcarbamoyl-AMP synthase involved in the biosynthesis of the threonylcarbamoyladenosine (t6A) residue at position 37 of ANN-decoding tRNAs gene gene3367 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16925 UM146_RS16930 UM146_16325 UM146_RS16930 3391276 3391818 - hypothetical protein gene gene3368 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16930 UM146_RS16935 UM146_16330 UM146_RS16935 3391847 3392320 - protein Smg gene gene3369 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16935 UM146_RS16940 UM146_16335 UM146_RS16940 3392292 3393416 - hypothetical protein gene gene3370 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16940 UM146_RS16945 UM146_16340 UM146_RS16945 3393546 3394055 + peptide deformylase gene gene3371 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16945 UM146_RS16950 UM146_16345 fmt fmt 3394070 3395017 + methionyl-tRNA formyltransferase modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation%3B inactivation of this gene in Escherichia coli severely impairs growth gene gene3372 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16950 UM146_RS16955 UM146_16350 UM146_RS16955 3395069 3396358 + ribosomal RNA small subunit methyltransferase B catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA%3B SAM-dependent methyltransferase gene gene3373 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16955 UM146_RS16960 UM146_16355 trkA trkA 3396380 3397756 + trk system potassium uptake protein trkA involved in potassium uptake%3B found to be peripherally associated with the inner membrane in Escherichia coli%3B contains an NAD-binding domain gene gene3374 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16960 UM146_RS16965 UM146_16360 mscL mscL 3397886 3398299 + large-conductance mechanosensitive channel forms homopentamer%3B channel that opens in response to pressure or hypoosmotic shock gene gene3375 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16965 UM146_RS16970 UM146_16365 UM146_RS16970 3398296 3398514 - regulator gene gene3376 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16970 UM146_RS16975 UM146_16370 zntR zntR 3398570 3398995 - zinc-responsive transcriptional regulator mediates expression of the zinc export protein ZntA in response to high levels of zinc%3B member of MerR family of transcriptional regulators gene gene3377 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16975 UM146_RS16980 UM146_16375 UM146_RS16980 3399006 3399374 - hypothetical protein gene gene3378 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16980 UM146_RS16985 UM146_16380 rplQ rplQ 3399481 3399864 - 50S ribosomal protein L17 is a component of the macrolide binding site in the peptidyl transferase center gene gene3379 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16985 UM146_RS16990 UM146_16385 UM146_RS16990 3399905 3400894 - DNA-directed RNA polymerase subunit alpha catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme gene gene3380 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16990 UM146_RS16995 UM146_16390 UM146_RS16995 3400920 3401540 - 30S ribosomal protein S4 gene gene3381 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS16995 UM146_RS17000 UM146_16395 UM146_RS17000 3401574 3401963 - 30S ribosomal protein S11 gene gene3382 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17000 UM146_RS17005 UM146_16400 UM146_RS17005 3401980 3402336 - 30S ribosomal protein S13 gene gene3383 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17005 UM146_RS17010 UM146_16405 UM146_RS17010 3402483 3402599 - 50S ribosomal protein L36 gene gene3384 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17010 UM146_RS17015 UM146_16410 secY secY 3402631 3403962 - protein translocase subunit SecY forms heterotrimeric complex in the membrane%3B in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG%3B the SecG subunit is not essential%3B in bacteria translocation is driven via the SecA ATPase gene gene3385 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17015 UM146_RS17020 UM146_16415 UM146_RS17020 3403970 3404404 - 50S ribosomal protein L15 gene gene3386 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17020 UM146_RS17025 UM146_16420 rpmD rpmD 3404408 3404587 - 50S ribosomal protein L30 L30 binds domain II of the 23S rRNA and the 5S rRNA%3B similar to eukaryotic protein L7 gene gene3387 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17025 UM146_RS17030 UM146_16425 UM146_RS17030 3404591 3405094 - 30S ribosomal protein S5 gene gene3388 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17030 UM146_RS17035 UM146_16430 UM146_RS17035 3405109 3405462 - 50S ribosomal protein L18 gene gene3389 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17035 UM146_RS17040 UM146_16435 UM146_RS17040 3405472 3406005 - 50S ribosomal protein L6 gene gene3390 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17040 UM146_RS17045 UM146_16440 UM146_RS17045 3406018 3406410 - 30S ribosomal protein S8 gene gene3391 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17045 UM146_RS17050 UM146_16445 rpsN rpsN 3406444 3406749 - 30S ribosomal protein S14 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit%3B similar to what is observed with proteins L31 and L33%2C some proteins in this family contain CXXC motifs that are involved in zinc binding%3B if two copies are present in a genome%2C then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc%3B the proteins in this group do not appear to have the zinc-binding motif gene gene3392 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17050 UM146_RS17055 UM146_16450 UM146_RS17055 3406764 3407303 - 50S ribosomal protein L5 gene gene3393 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17055 UM146_RS17060 UM146_16455 rplX rplX 3407318 3407632 - 50S ribosomal protein L24 assembly initiator protein%3B binds to 5' end of 23S rRNA and nucleates assembly of the 50S%3B surrounds polypeptide exit tunnel gene gene3394 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17060 UM146_RS17065 UM146_16460 UM146_RS17065 3407643 3408014 - 50S ribosomal protein L14 gene gene3395 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17065 UM146_RS17070 UM146_16465 UM146_RS17070 3408179 3408433 - 30S ribosomal protein S17 gene gene3396 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17070 UM146_RS17075 UM146_16470 UM146_RS17075 3408433 3408624 - 50S ribosomal protein L29 one of the stabilizing components for the large ribosomal subunit gene gene3397 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17075 UM146_RS17080 UM146_16475 UM146_RS17080 3408624 3409034 - 50S ribosomal protein L16 gene gene3398 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17080 UM146_RS17085 UM146_16480 UM146_RS17085 3409047 3409748 - 30S ribosomal protein S3 gene gene3399 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17085 UM146_RS17090 UM146_16485 UM146_RS17090 3409766 3410098 - 50S ribosomal protein L22 gene gene3400 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17090 UM146_RS17095 UM146_16490 UM146_RS17095 3410113 3410391 - 30S ribosomal protein S19 gene gene3401 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17095 UM146_RS17100 UM146_16495 UM146_RS17100 3410408 3411229 - 50S ribosomal protein L2 gene gene3402 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17100 UM146_RS17105 UM146_16500 rplW rplW 3411247 3411549 - 50S ribosomal protein L23 binds third domain of 23S rRNA and protein L29%3B part of exit tunnel gene gene3403 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17105 UM146_RS17110 UM146_16505 rplD rplD 3411546 3412151 - 50S ribosomal protein L4 L4 is important during the early stages of 50S assembly%3B it initially binds near the 5' end of the 23S rRNA gene gene3404 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17110 UM146_RS17115 UM146_16510 UM146_RS17115 3412162 3412791 - 50S ribosomal protein L3 gene gene3405 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17115 UM146_RS17120 UM146_16515 rpsJ rpsJ 3412824 3413135 - 30S ribosomal protein S10 NusE%3B involved in assembly of the 30S subunit%3B in the ribosome%2C this protein is involved in the binding of tRNA%3B in Escherichia coli this protein was also found to be involved in transcription antitermination%3B NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination%3B binding of NusB/S10 to boxA nucleates assembly of the antitermination complex gene gene3406 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17120 UM146_RS17125 UM146_16520 UM146_RS17125 3413373 3413792 - protein secretion protein GspB involved in type II protein secretion gene gene3407 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17125 UM146_RS17130 UM146_16525 UM146_RS17130 3413794 3415263 - general secretion pathway protein GspA gene gene3408 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17130 UM146_RS17135 UM146_16530 UM146_RS17135 3415443 3416258 + type II secretion system protein GspC gene gene3409 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17135 UM146_RS17140 UM146_16535 UM146_RS17140 3416242 3418194 + type II secretion system protein GspD gene gene3410 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17140 UM146_RS17145 UM146_16540 UM146_RS17145 3418204 3419685 + type II secretion system protein GspE gene gene3411 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17145 UM146_RS17150 UM146_16545 UM146_RS17150 3419682 3420878 + type II secretion system protein GspF gene gene3412 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17150 UM146_RS17155 UM146_16550 UM146_RS17155 3420888 3421325 + type II secretion system protein GspG gene gene3413 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17155 UM146_RS17160 UM146_16555 UM146_RS17160 3421333 3421842 + type II secretion system protein GspH gene gene3414 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17160 UM146_RS17165 UM146_16560 UM146_RS17165 3421839 3422252 + type II secretion system protein GspI gene gene3415 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17165 UM146_RS17170 UM146_16565 UM146_RS17170 3422245 3422832 + type II secretion system protein J gene gene3416 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17170 UM146_RS17175 UM146_16570 UM146_RS17175 3422825 3423808 + type II secretion system protein K gene gene3417 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17175 UM146_RS17180 UM146_16575 UM146_RS17180 3423823 3424986 + type II secretion system protein GspL gene gene3418 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17180 UM146_RS17185 UM146_16580 UM146_RS17185 3424983 3425444 + general secretion pathway protein GspM gene gene3419 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17185 UM146_RS17190 UM146_16585 UM146_RS17190 3425444 3426121 + methyltransferase gene gene3420 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17190 UM146_RS17195 UM146_16590 UM146_RS17195 3426150 3426626 - bacterioferritin iron storage protein gene gene3421 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17195 UM146_RS17200 UM146_16595 UM146_RS17200 3426698 3426892 - bacterioferritin-associated ferredoxin gene gene3422 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17200 UM146_RS17205 UM146_16600 UM146_RS17205 3427061 3429763 - lysozyme gene gene3423 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17205 UM146_RS17210 UM146_16605 tuf tuf 3430055 3431239 - translation elongation factor EF-Tu 1 EF-Tu%3B promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B when the tRNA anticodon matches the mRNA codon%2C GTP hydrolysis results%3B the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts%3B many prokaryotes have two copies of the gene encoding EF-Tu gene gene3424 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17210 UM146_RS17215 UM146_t23935 UM146_RS17215 3431354 3431429 - tRNA-Thr tRNA gene3425 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17215 UM146_RS17220 UM146_t23937 UM146_RS17220 3431436 3431510 - tRNA-Gly tRNA gene3426 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17220 UM146_RS17225 UM146_t23939 UM146_RS17225 3431627 3431711 - tRNA-Tyr tRNA gene3427 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17225 UM146_RS17230 UM146_t23941 UM146_RS17230 3431720 3431795 - tRNA-Thr tRNA gene3428 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17230 UM146_RS17235 UM146_RS17235 UM146_RS17235 3431815 3431970 + hypothetical protein gene gene3429 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17235 UM146_RS17240 UM146_16615 UM146_RS17240 3432151 3433107 + type I pantothenate kinase gene gene3430 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17240 UM146_RS17245 UM146_16620 UM146_RS17245 3433136 3434101 - bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor catalyzes the formation of biotinyl-5'-AMP%2C also acts as a transcriptional repressor of the biotin operon gene gene3431 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17245 UM146_RS17250 UM146_16625 murB murB 3434098 3435126 - UDP-N-acetylenolpyruvoylglucosamine reductase catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis gene gene3432 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17250 UM146_RS17255 UM146_r23997 UM146_RS17255 3435263 3435378 - 5S ribosomal RNA rRNA gene3433 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17255 UM146_RS17260 UM146_r24023 UM146_RS17260 3435463 3438387 - 23S ribosomal RNA rRNA gene3434 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17260 UM146_RS17265 UM146_t23943 UM146_RS17265 3438572 3438647 - tRNA-Glu tRNA gene3435 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17265 UM146_RS17270 UM146_r24009 UM146_RS17270 3438721 3440276 - 16S ribosomal RNA rRNA gene3436 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17270 UM146_RS17275 UM146_16630 purH purH 3440891 3442480 + bifunctional purine biosynthesis protein PurH involved in de novo purine biosynthesis gene gene3439 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17275 UM146_RS17280 UM146_16635 UM146_RS17280 3442492 3443781 + phosphoribosylamine--glycine ligase catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis gene gene3440 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17280 UM146_RS17285 UM146_RS17285 UM146_RS17285 3443778 3445102 - transcriptional regulator DNA-binding response regulator in two-component regulatory system with ZraS%3B response regulator/sigma54 interaction protein gene gene3441 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17285 UM146_RS17290 UM146_16650 UM146_RS17290 3445099 3446475 - two-component system sensor histidine kinase gene gene3442 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17290 UM146_RS17295 UM146_16655 zraP zraP 3446713 3447132 + zinc resistance-associated protein gene gene3443 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17295 UM146_RS17300 UM146_16660 UM146_RS17300 3447134 3447829 - membrane protein gene gene3444 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17300 UM146_RS17305 UM146_16665 UM146_RS17305 3447842 3448114 - DNA-binding protein HU-alpha gene gene3445 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17305 UM146_RS17310 UM146_16670 UM146_RS17310 3448301 3448891 - hypothetical protein gene gene3446 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17310 UM146_RS17315 UM146_16675 UM146_RS17315 3448934 3449605 - endonuclease V Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA%3B cleaves DNA containing urea residues%2C AP sites%2C base mismatches%2C insertion/deletion mismatches%2C flaps%2C and pseudo-Y structures gene gene3447 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17315 UM146_RS17320 UM146_16680 hemE hemE 3449615 3450679 - uroporphyrinogen decarboxylase catalyzes the formation of coproporphyrinogen from uroporphyrinogen III gene gene3448 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17320 UM146_RS17325 UM146_16685 nudC nudC 3450719 3451492 - NADH pyrophosphatase can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH%3B requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates gene gene3449 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17325 UM146_RS17330 UM146_16690 UM146_RS17330 3451587 3452063 + regulator of sigma D binds specifically to the major sigma factor sigma 70%3B active in stationary phase gene gene3450 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17330 UM146_RS17335 UM146_16695 UM146_RS17335 3452296 3454191 + phosphomethylpyrimidine synthase catalyzes the formation of 4-amino-2-methyl-5-phosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole and S-adenosyl-L-methionine in thiamine biosynthesis gene gene3451 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17335 UM146_RS17340 UM146_16700 UM146_RS17340 3454191 3454826 + thiamine-phosphate synthase catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate gene gene3452 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17340 UM146_RS17345 UM146_16705 UM146_RS17345 3454819 3455574 + molybdopterin biosynthesis protein MoeB ATP-dependent adenylate transferase%2C transfers adenyl moiety to the MoeD subunit of molybdopterin synthase gene gene3453 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17345 UM146_RS17350 UM146_16710 UM146_RS17350 3455558 3455758 + thiamine biosynthesis protein ThiS with ThiF%2C ThiG%2C and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate gene gene3454 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17350 UM146_RS17355 UM146_16715 UM146_RS17355 3455760 3456530 + thiazole synthase gene gene3455 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17355 UM146_RS17360 UM146_16720 thiH thiH 3456527 3457660 + thiamine biosynthesis protein ThiH in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS%3B with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine%2C cysteine and 1-deoxy-D-xylulose-5-phosphate%3B forms a complex with ThiG%3B contains an iron-sulfur center gene gene3456 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17360 UM146_RS17365 UM146_16725 UM146_RS17365 3457900 3462123 - DNA-directed RNA polymerase subunit beta' DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter gene gene3457 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17365 UM146_RS17370 UM146_16730 rpoB rpoB 3462200 3466228 - DNA-directed RNA polymerase subunit beta DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme gene gene3458 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17370 UM146_RS17375 UM146_16735 rplL rplL 3466548 3466913 - 50S ribosomal protein L7/L12 present in two forms%3B L12 is normal%2C while L7 is aminoacylated at the N-terminal serine%3B the only multicopy ribosomal protein%3B 4:1 ratio of L7/L12 per ribosome%3B two L12 dimers bind L10%3B critically important for translation efficiency and fidelity%3B stimulates GTPase activity of translation factors gene gene3459 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17375 UM146_RS17380 UM146_16740 rplJ rplJ 3466980 3467477 - 50S ribosomal protein L10 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit gene gene3460 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17380 UM146_RS17385 UM146_16745 UM146_RS17385 3467769 3468473 - 50S ribosomal protein L1 gene gene3461 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17385 UM146_RS17390 UM146_16750 UM146_RS17390 3468477 3468905 - 50S ribosomal protein L11 gene gene3462 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17390 UM146_RS17395 UM146_16755 nusG nusG 3469064 3469609 - transcription termination/antitermination protein NusG Modulates Rho-dependent transcription termination gene gene3463 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17395 UM146_RS17400 UM146_16760 secE secE 3469611 3469994 - protein translocase subunit SecE forms a complex with SecY and SecG%3B SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane%2C a process driven by ATP and a proton-motive force gene gene3464 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17400 UM146_RS17405 UM146_16765 tuf tuf 3470224 3471408 - translation elongation factor EF-Tu 2 EF-Tu%3B promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B when the tRNA anticodon matches the mRNA codon%2C GTP hydrolysis results%3B the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts%3B many prokaryotes have two copies of the gene encoding EF-Tu gene gene3465 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17405 UM146_RS17410 UM146_16770 fusA fusA 3471479 3473593 - elongation factor G EF-G%3B promotes GTP-dependent translocation of the ribosome during translation%3B many organisms have multiple copies of this gene gene gene3466 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17410 UM146_RS17415 UM146_16775 UM146_RS17415 3473690 3474160 - 30S ribosomal protein S7 gene gene3467 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17415 UM146_RS17420 UM146_16780 UM146_RS17420 3474257 3474631 - 30S ribosomal protein S12 gene gene3468 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17420 UM146_RS17425 UM146_16785 UM146_RS17425 3474757 3475044 - protein TusB in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs gene gene3469 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17425 UM146_RS17430 UM146_16790 UM146_RS17430 3475051 3475410 - protein TusC in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur transfer that results in thiouridation to U34 position in some tRNAs gene gene3470 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17430 UM146_RS17435 UM146_16795 UM146_RS17435 3475410 3475796 - sulfurtransferase TusD in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs gene gene3471 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17435 UM146_RS17440 UM146_16800 UM146_RS17440 3475796 3476518 - transcriptional regulator gene gene3472 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17440 UM146_RS17445 UM146_16805 UM146_RS17445 3476685 3477497 - FKBP-type peptidyl-prolyl cis-trans isomerase rotamase gene gene3473 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17445 UM146_RS17450 UM146_16810 UM146_RS17450 3477718 3477936 + protein SlyX required for phi X174 lysis gene gene3474 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17450 UM146_RS17455 UM146_16815 UM146_RS17455 3477984 3478574 - FKBP-type peptidyl-prolyl cis-trans isomerase rotamase gene gene3475 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17455 UM146_RS17460 UM146_16820 UM146_RS17460 3478669 3478869 - hypothetical protein gene gene3476 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17460 UM146_RS17465 UM146_16825 UM146_RS17465 3478879 3480684 - glutathione-regulated potassium-efflux system protein KefB involved in potassium efflux gene gene3477 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17465 UM146_RS17470 UM146_16830 UM146_RS17470 3480684 3481235 - potassium transporter required for KefB activity gene gene3478 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17470 UM146_RS17475 UM146_16835 UM146_RS17475 3481366 3483279 + glutathione ABC transporter ATP-binding protein gene gene3479 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17475 UM146_RS17480 UM146_16840 UM146_RS17480 3483279 3484301 + hydrolase gene gene3480 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17480 UM146_RS17485 UM146_16845 UM146_RS17485 3484295 3484513 + hypothetical protein gene gene3481 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17485 UM146_RS17490 UM146_16850 UM146_RS17490 3484567 3485436 + phosphoribulokinase gene gene3482 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17490 UM146_RS17495 UM146_16855 UM146_RS17495 3485491 3485895 - hypothetical protein gene gene3483 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17495 UM146_RS17500 UM146_RS17500 UM146_RS17500 3485975 3486190 + hypothetical protein gene gene3484 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17500 UM146_RS17505 UM146_16860 UM146_RS17505 3486197 3486829 + cAMP-activated global transcriptional regulator CRP cAMP receptor protein%3B complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons gene gene3485 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17505 UM146_RS17510 UM146_16865 UM146_RS17510 3486880 3488970 + membrane protein gene gene3486 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17510 UM146_RS17515 UM146_16875 argD argD 3489037 3490257 - succinyldiaminopimelate aminotransferase DapATase%3B bifunctional enzyme that functions in arginine and lysine biosynthetic pathways%3B catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2%2C6-diaminoheptanedioate gene gene3487 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17515 UM146_RS17520 UM146_16880 UM146_RS17520 3490343 3490906 - anthranilate synthase subunit II TrpG%3B with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine%3B TrpG provides the glutamine amidotransferase activity gene gene3488 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17520 UM146_RS17525 UM146_16885 UM146_RS17525 3490938 3491540 - cell filamentation protein Fic gene gene3489 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17525 UM146_RS17530 UM146_16890 UM146_RS17530 3491530 3491697 - hypothetical protein gene gene3490 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17530 UM146_RS17535 UM146_RS17535 UM146_RS17535 3491802 3492373 - peptidylprolyl isomerase gene gene3491 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17535 UM146_RS17540 UM146_16905 UM146_RS17540 3492643 3493824 + protein TsgA gene gene3492 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17540 UM146_RS17545 UM146_16910 UM146_RS17545 3494086 3496629 + nitrite reductase subunit NirD gene gene3493 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17545 UM146_RS17550 UM146_16915 nirD nirD 3496626 3496952 + nitrite reductase small subunit involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+%3B bounds to NirB%2C the cytoplasmic subunit%2C whose expression is induced at high nitrate concentrations gene gene3494 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17550 UM146_RS17555 UM146_16920 UM146_RS17555 3497078 3497884 + nitrite transporter NirC member of the FNT family of formate and nitrite transporters gene gene3495 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17555 UM146_RS17560 UM146_16925 cysG cysG 3497903 3499276 + siroheme synthase multifunction enzyme consisting of uroporphyrin-III C-methyltransferase%2C precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase%3B catalyzes the methylation of uroporphyrinogen III to form precorrin-2%2C then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin gene gene3496 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17560 UM146_RS17565 UM146_16930 UM146_RS17565 3499528 3499695 + lipoprotein gene gene3497 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17565 UM146_RS17570 UM146_16935 UM146_RS17570 3499803 3500888 - hypothetical protein gene gene3498 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17570 UM146_RS17575 UM146_16940 UM146_RS17575 3500900 3502204 - membrane protein gene gene3499 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17575 UM146_RS17580 UM146_16945 UM146_RS17580 3502216 3502569 - DUF2620 domain-containing protein gene gene3500 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17580 UM146_RS17585 UM146_16950 UM146_RS17585 3502580 3503458 - hydrolase phosphotriesterase homology protein%3B PhP%3B YhfV%3B member of a family of proteins related to phosphotriesterase (PTE) gene gene3501 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17585 UM146_RS17590 UM146_16955 UM146_RS17590 3503455 3504681 - mutase gene gene3502 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17590 UM146_RS17595 UM146_16960 UM146_RS17595 3504682 3505845 - hypothetical protein gene gene3503 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17595 UM146_RS17600 UM146_16965 UM146_RS17600 3505929 3506291 - hypothetical protein gene gene3504 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17600 UM146_RS17605 UM146_16970 UM146_RS17605 3506308 3507213 - hypothetical protein gene gene3505 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17605 UM146_RS17610 UM146_16975 UM146_RS17610 3507373 3508377 - tryptophan--tRNA ligase gene gene3506 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17610 UM146_RS17615 UM146_16980 UM146_RS17615 3508370 3509128 - phosphoglycolate phosphatase catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate gene gene3507 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17615 UM146_RS17620 UM146_16985 UM146_RS17620 3509121 3509798 - ribulose-phosphate 3-epimerase gene gene3508 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17620 UM146_RS17625 UM146_16990 UM146_RS17625 3509816 3510652 - DNA adenine methylase gene gene3509 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17625 UM146_RS17630 UM146_16995 UM146_RS17630 3510759 3512045 - cell division protein DamX binds the septal ring gene gene3510 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17630 UM146_RS17635 UM146_17000 aroB aroB 3512137 3513225 - 3-dehydroquinate synthase catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate%3B functions in aromatic amino acid biosynthesis gene gene3511 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17635 UM146_RS17640 UM146_RS17640 aroK aroK 3513282 3513803 - shikimate kinase type I enzyme similar to type II but differentially regulated%3B major shikimate kinase in fully repressed cells%3B catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis gene gene3512 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17640 UM146_RS17645 UM146_17010 hofQ hofQ 3514204 3515364 - porin outer membrane porin probably involved in uptake of extracellular double-stranded DNA%3B similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa gene gene3513 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17645 UM146_RS17650 UM146_17015 UM146_RS17650 3515354 3515758 - DNA utilization protein HofP gene gene3514 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17650 UM146_RS17655 UM146_17020 UM146_RS17655 3515748 3516188 - DNA utilization protein HofO gene gene3515 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17655 UM146_RS17660 UM146_17025 UM146_RS17660 3516172 3516711 - DNA utilization protein HofN gene gene3516 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17660 UM146_RS17665 UM146_17030 UM146_RS17665 3516711 3517490 - DNA utilization protein HofM gene gene3517 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17665 UM146_RS17670 UM146_17035 mrcA mrcA 3517610 3520162 + penicillin-binding protein 1A bifunctional murein transglycosylase/murein transpeptidase%3B penicillin-binding protein 1A%3B involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation%3B penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits gene gene3518 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17670 UM146_RS17675 UM146_17040 nudE nudE 3520328 3520888 - adenosine nucleotide hydrolase ADP-sugar pyrophosphatase%3B catalyzes the formation of D-ribose 5-phosphate from ADP-ribose%3B can also act on ADP-mannose and ADP-glucose gene gene3519 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17675 UM146_RS17680 UM146_17045 UM146_RS17680 3521208 3523343 + intracellular growth attenuator protein IgaA gene gene3520 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17680 UM146_RS17685 UM146_17050 UM146_RS17685 3523408 3524076 + GMP/IMP nucleotidase YrfG gene gene3521 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17685 UM146_RS17690 UM146_17055 UM146_RS17690 3524087 3524488 + heat-shock protein 15 gene gene3522 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17690 UM146_RS17695 UM146_17060 hslO hslO 3524513 3525391 + heat-shock protein Hsp33 becomes active under oxidative stress%3B four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive%3B oxidative stress results in oxidized cysteines%2C release of zinc%2C and binding of Hsp33 to aggregation-prone proteins%3B forms dimers and higher order oligomers gene gene3523 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17695 UM146_RS17700 UM146_17065 UM146_RS17700 3525454 3527178 - membrane protein gene gene3524 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17700 UM146_RS17705 UM146_RS17705 UM146_RS17705 3527254 3527385 - hypothetical protein gene gene3525 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17705 UM146_RS17710 UM146_17070 UM146_RS17710 3527557 3529179 + phosphoenolpyruvate carboxykinase [ATP] PEP carboxykinase%3B PEP carboxylase%3B PEPCK%3B catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP gene gene3526 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17710 UM146_RS17715 UM146_17075 envZ envZ 3529255 3530607 - two-component system sensor histidine kinase membrane-localized osmosensor%3B histidine kinase%3B in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR gene gene3527 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17715 UM146_RS17720 UM146_17080 ompR ompR 3530604 3531323 - two-component system response regulator part of two-component system EnvZ/OmpR%3B regulates transcription of outer membrane porin genes ompC/F%3B under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR%3B the result is increased expression of ompC and repression of ompF%3B also functions in regulation of other genes%3B forms dimers upon phosphorylation gene gene3528 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17720 UM146_RS17725 UM146_17085 greB greB 3531551 3532027 + transcription elongation factor GreB necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites%3B arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus gene gene3529 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17725 UM146_RS17730 UM146_17090 UM146_RS17730 3532124 3534445 + transcription accessory protein gene gene3530 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17730 UM146_RS17735 UM146_17095 feoA feoA 3534885 3535112 + ferrous iron transporter A gene gene3531 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17735 UM146_RS17740 UM146_17100 feoB feoB 3535129 3537450 + ferrous iron transporter B cytoplasmic membrane ferrous uptake system permease%3B mutations disrupt the ability of Escherichia coli to take up ferrous iron%3B GTP-binding protein which requires GTP for efficient iron(II) uptake gene gene3532 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17740 UM146_RS17745 UM146_17105 UM146_RS17745 3537461 3537697 + ferrous iron transporter C regulatory protein that controls transcription of feoABC genes gene gene3533 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17745 UM146_RS17750 UM146_17110 UM146_RS17750 3537900 3538793 + transposase gene gene3534 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17750 UM146_RS17755 UM146_17120 UM146_RS17755 3539013 3539783 - pimeloyl-[acyl-carrier protein] methyl ester esterase Shows carboxylesterase activity with a preference for short chain fatty acid esters%3B involved in pimeloyl-CoA synthesis gene gene3535 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17755 UM146_RS17760 UM146_17125 UM146_RS17760 3539821 3540504 + protein GntX required for utilization of DNA as the sole source of carbon and energy gene gene3536 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17760 UM146_RS17765 UM146_17130 UM146_RS17765 3540563 3541138 + fe/S biogenesis protein nfuA cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source gene gene3537 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17765 UM146_RS17770 UM146_17135 UM146_RS17770 3541499 3542815 + gluconate transporter gene gene3538 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17770 UM146_RS17775 UM146_17140 malQ malQ 3542860 3544944 - 4-alpha-glucanotransferase amylomaltase%3B acts to release glucose from maltodextrins gene gene3539 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17775 UM146_RS17780 UM146_17145 UM146_RS17780 3544954 3547347 - glycogen phosphorylase gene gene3540 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17780 UM146_RS17785 UM146_17150 UM146_RS17785 3547970 3550675 + transcriptional regulator Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides gene gene3541 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17785 UM146_RS17790 UM146_17155 UM146_RS17790 3550718 3551734 - RNA 3'-terminal phosphate cyclase catalyzes the conversion of terminal3'-phosphate of RNA to the 2'%2C3'-cyclicphosphodiester gene gene3542 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17790 UM146_RS17795 UM146_17160 UM146_RS17795 3551738 3552964 - RNA-splicing ligase gene gene3543 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17795 UM146_RS17800 UM146_17165 UM146_RS17800 3553153 3554751 + Fis family transcriptional regulator sigma 54-dependent%3B regulates genes involved in forming a 2'%2C3'-cyclic phosphodiester on RNA gene gene3544 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17800 UM146_RS17805 UM146_17170 UM146_RS17805 3554733 3555491 - transcriptional regulator represses the glpD%2C glpFK%2C glpTQ%2C and glpACB operons involved in glycerol-3-phosphate metabolism gene gene3545 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17805 UM146_RS17810 UM146_17175 UM146_RS17810 3555508 3556338 - rhomboid protease GlpG protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity gene gene3546 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17810 UM146_RS17815 UM146_17180 glpE glpE 3556383 3556709 - thiosulfate sulfurtransferase GlpE belongs to rhodanese family%3B thiosulfate thiotransferase%3B in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency%3B contains an active site cysteine gene gene3547 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17815 UM146_RS17820 UM146_17185 glpD glpD 3556899 3558404 + glycerol-3-phosphate dehydrogenase in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions%3B anaerobic expression is repressed by the arcAB system%3B converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8%3B associates with the cytoplasmic membrane gene gene3548 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17820 UM146_RS17825 UM146_17190 UM146_RS17825 3558458 3559063 - membrane protein gene gene3549 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17825 UM146_RS17830 UM146_17195 UM146_RS17830 3559066 3559833 - hypothetical protein gene gene3550 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17830 UM146_RS17835 UM146_17200 UM146_RS17835 3559836 3560546 - hypothetical protein gene gene3551 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17835 UM146_RS17840 UM146_RS17840 UM146_RS17840 3560719 3561839 - fimbrial protein gene gene3552 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17840 UM146_RS17845 UM146_17215 UM146_RS17845 3561854 3562633 - pilin chaperone gene gene3553 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17845 UM146_RS17850 UM146_17220 UM146_RS17850 3562599 3563171 - fimbrial protein gene gene3554 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17850 UM146_RS17855 UM146_17225 UM146_RS17855 3563122 3563685 - fimbrial protein gene gene3555 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17855 UM146_RS17860 UM146_17230 UM146_RS17860 3563685 3566279 - outer membrane usher protein gene gene3556 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17860 UM146_RS17865 UM146_RS17865 UM146_RS17865 3566316 3567067 - fimbrial chaperone protein FimC involved in type 1 fimbriae biosynthesis%2C interacts with FimH gene gene3557 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17865 UM146_RS17870 UM146_17240 UM146_RS17870 3567168 3567872 - Auf fimbriae major fimbrial subunit AufA gene gene3558 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17870 UM146_RS17875 UM146_17245 UM146_RS17875 3568366 3570813 - glycogen phosphorylase gene gene3559 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17875 UM146_RS17880 UM146_17250 glgA glgA 3570832 3572265 - glycogen synthase catalyzes the formation of alpha-1%2C4-glucan chains from ADP-glucose gene gene3560 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17880 UM146_RS17885 UM146_17255 glgC glgC 3572265 3573560 - glucose-1-phosphate adenylyltransferase catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate gene gene3561 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17885 UM146_RS17890 UM146_17260 UM146_RS17890 3573578 3575551 - glycogen debranching protein catalyzes the hydrolysis of the alpha-1%2C6-glucosidic linkages in partially depolymerized glycogen gene gene3562 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17890 UM146_RS17895 UM146_17265 UM146_RS17895 3575548 3577734 - glycogen-branching protein gene gene3563 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17895 UM146_RS17900 UM146_17270 UM146_RS17900 3578007 3579110 - aspartate-semialdehyde dehydrogenase catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde gene gene3564 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17900 UM146_RS17905 UM146_17275 UM146_RS17905 3579302 3579895 + membrane protein gene gene3565 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17905 UM146_RS17910 UM146_17280 UM146_RS17910 3579952 3581292 - gluconate transporter gene gene3566 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17910 UM146_RS17915 UM146_17285 gntK gntK 3581296 3581823 - gluconate kinase thermoresistant%3B catalyzes the formation of 6-phospho-D-gluconate from gluconate gene gene3567 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17915 UM146_RS17920 UM146_17290 UM146_RS17920 3581962 3582957 - transcriptional regulator gene gene3568 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17920 UM146_RS17925 UM146_17295 UM146_RS17925 3583050 3583745 - quercetin 2%2C3-dioxygenase gene gene3569 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17925 UM146_RS17930 UM146_17300 UM146_RS17930 3583868 3584905 - oxidoreductase gene gene3570 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17930 UM146_RS17935 UM146_17305 UM146_RS17935 3585238 3585726 + acetyltransferase YhhY%3B regulated by the fur regulator%3B unknown function gene gene3571 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17935 UM146_RS17940 UM146_RS17940 UM146_RS17940 3585962 3587140 + hypothetical protein gene gene3572 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17940 UM146_RS17945 UM146_17315 UM146_RS17945 3587137 3587631 + hypothetical protein gene gene3573 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17945 UM146_RS17950 UM146_17320 UM146_RS17950 3588081 3588365 + hypothetical protein gene gene3574 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17950 UM146_RS17955 UM146_17325 ggt ggt 3588403 3590136 - gamma-glutamyltranspeptidase periplasmic enzyme%3B post-translationally processed into two subunits which are required for wild-type enzyme activity%3B cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides gene gene3575 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17955 UM146_RS17960 UM146_17330 UM146_RS17960 3590256 3590696 + membrane protein gene gene3576 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17960 UM146_RS17965 UM146_17335 ugpQ ugpQ 3590683 3591426 - glycerophosphodiester phosphodiesterase hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol%3B induced when cells are starved for inorganic phosphate gene gene3577 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17965 UM146_RS17970 UM146_17340 ugpC ugpC 3591423 3592493 - sn-glycerol-3-phosphate import ATP-binding protein UgpC part of the UgpABCE glycerol-3-phosphate uptake system gene gene3578 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17970 UM146_RS17975 UM146_17345 UM146_RS17975 3592495 3593340 - sn-glycerol 3-phosphate ABC transporter permease with UgpABC is involved in uptake of glycerol-3-phosphate gene gene3579 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17975 UM146_RS17980 UM146_17350 UM146_RS17980 3593337 3594224 - sn-glycerol 3-phosphate ABC transporter permease with UgpEC is involved in the uptake of glycerol-3-phosphate gene gene3580 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17980 UM146_RS17985 UM146_17355 UM146_RS17985 3594322 3595638 - sn-glycerol-3-phosphate-binding periplasmic protein UgpB with UgpACE is involved in the uptake of glycerol-3-phosphate gene gene3581 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17985 UM146_RS17990 UM146_RS17990 UM146_RS17990 3595871 3595999 - hypothetical protein gene gene3582 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17990 UM146_RS17995 UM146_17360 livF livF 3596035 3596748 - branched-chain amino acid ABC transporter ATP-binding protein with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system%3B LivFGHMK is specific for the transport of leucine%2C while LivFGHMJ is a transporter for leucine%2C isoleucine%2C and valine gene gene3583 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS17995 UM146_RS18000 UM146_17365 livG livG 3596750 3597517 - branched-chain amino acid ABC transporter ATP-binding protein Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids%3B LivFGHMK is specific for the transport of leucine%2C while LivFGHMJ is a transporter for leucine%2C isoleucine%2C and valine gene gene3584 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18000 UM146_RS18005 UM146_17370 livM livM 3597514 3598791 - branched-chain amino acid ABC transporter permease Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids%3B LivFGHMK is specific for the transport of leucine%2C while LivFGHMJ is a transporter for leucine%2C isoleucine%2C and valine gene gene3585 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18005 UM146_RS18010 UM146_17375 UM146_RS18010 3598788 3599714 - branched-chain amino acid transporter permease subunit LivH LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter gene gene3586 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18010 UM146_RS18015 UM146_17380 UM146_RS18015 3599762 3600871 - amino acid ABC transporter substrate-binding protein with LivFGHM is involved in the high affinity leucine transport gene gene3587 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18015 UM146_RS18020 UM146_17385 UM146_RS18020 3601295 3601678 + hypothetical protein gene gene3588 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18020 UM146_RS18025 UM146_17390 UM146_RS18025 3601688 3601810 + hypothetical protein gene gene3589 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18025 UM146_RS18030 UM146_17395 UM146_RS18030 3601866 3602984 - amino acid ABC transporter substrate-binding protein with LivFGHM is involved in the high affinity leucine transport gene gene3590 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18030 UM146_RS18035 UM146_17400 UM146_RS18035 3603904 3604305 + PTS mannose transporter subunit IIA gene gene3591 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18035 UM146_RS18040 UM146_17405 UM146_RS18040 3604312 3604797 + PTS sugar transporter gene gene3592 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18040 UM146_RS18045 UM146_17410 UM146_RS18045 3604814 3605560 + PTS sorbose transporter subunit IIC gene gene3593 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18045 UM146_RS18050 UM146_17415 UM146_RS18050 3605553 3606407 + PTS fructose transporter subunit IID gene gene3594 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18050 UM146_RS18055 UM146_17420 UM146_RS18055 3606409 3607329 + phosphoglycerate dehydrogenase gene gene3595 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18055 UM146_RS18060 UM146_17425 UM146_RS18060 3607329 3608213 + 4-hydroxy-tetrahydrodipicolinate synthase gene gene3596 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18060 UM146_RS18065 UM146_17430 UM146_RS18065 3608317 3609171 - RNA polymerase sigma factor RpoH binds with the catalytic core of RNA polymerase to produce the holoenzyme%3B this sigma factor is responsible for the expression of heat shock promoters gene gene3597 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18065 UM146_RS18070 UM146_17435 ftsX ftsX 3609416 3610474 - cell division protein FtsX ABC transporter%2C membrane protein gene gene3598 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18070 UM146_RS18075 UM146_17440 UM146_RS18075 3610467 3611135 - cell division ATP-binding protein FtsE ATP-binding protein of an ATP-binding cassette transporter%3B when bound to FtsX%2C FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions gene gene3599 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18075 UM146_RS18080 UM146_17445 UM146_RS18080 3611138 3612634 - signal recognition particle-docking protein FtsY cell division protein%3B signal recognition protein receptor%3B functions in the targeting and insertion of membrane proteins gene gene3600 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18080 UM146_RS18085 UM146_17450 rsmD rsmD 3612784 3613380 + ribosomal RNA small subunit methyltransferase D catalyzes the methylation of 16S rRNA at position G966 gene gene3601 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18085 UM146_RS18090 UM146_17455 UM146_RS18090 3613370 3613639 + membrane protein gene gene3602 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18090 UM146_RS18095 UM146_17460 UM146_RS18095 3613642 3614001 - hypothetical protein gene gene3603 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18095 UM146_RS18100 UM146_17465 UM146_RS18100 3614142 3614768 + membrane protein gene gene3604 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18100 UM146_RS18105 UM146_17470 zntA zntA 3614842 3617040 + cadmium-transporting ATPase P-type ATPase involved in the export of lead%2C cadmium%2C zinc and mercury gene gene3605 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18105 UM146_RS18110 UM146_17475 UM146_RS18110 3617309 3617554 - sulfurtransferase TusA TusA%3B transfers sulfur to TusBCD complex%3B involved in thiouridation of U34 position of some tRNAs gene gene3606 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18110 UM146_RS18115 UM146_17480 UM146_RS18115 3617775 3618440 + membrane protein gene gene3607 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18115 UM146_RS18120 UM146_17485 UM146_RS18120 3618513 3619070 + hypothetical protein gene gene3608 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18120 UM146_RS18125 UM146_17490 UM146_RS18125 3619074 3620291 - MFS transporter gene gene3609 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18125 UM146_RS18130 UM146_17495 UM146_RS18130 3620423 3621472 + pheromone autoinducer 2 transporter gene gene3610 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18130 UM146_RS18135 UM146_17500 UM146_RS18135 3621527 3622114 + ACP synthase gene gene3611 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18135 UM146_RS18140 UM146_17505 UM146_RS18140 3622225 3623799 + nickel ABC transporter substrate-binding protein gene gene3612 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18140 UM146_RS18145 UM146_17510 UM146_RS18145 3623799 3624743 + nickel ABC transporter permease with NikACDE is involved in nickel transport into the cell gene gene3613 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18145 UM146_RS18150 UM146_17515 nikC nikC 3624740 3625573 + nickel ABC transporter permease with NikABDE is involved in nickel transport into the cell gene gene3614 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18150 UM146_RS18155 UM146_17520 nikD nikD 3625573 3626337 + nickel import ATP-binding protein NikD with NikABCE is involved in nickel transport into the cell gene gene3615 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18155 UM146_RS18160 UM146_17525 nikE nikE 3626334 3627140 + nickel import ATP-binding protein NikE with NikABCD is involved with nickel transport into the cell gene gene3616 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18160 UM146_RS18165 UM146_17530 UM146_RS18165 3627146 3627547 + nickel-responsive regulator Inhibits transcription at high concentrations of nickel gene gene3617 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18165 UM146_RS18170 UM146_17540 UM146_RS18170 3627746 3628492 + hypothetical protein gene gene3618 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18170 UM146_RS18175 UM146_17545 UM146_RS18175 3628517 3628990 + PTS sugar transporter subunit IIA gene gene3619 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18175 UM146_RS18180 UM146_17550 UM146_RS18180 3628987 3629268 + PTS sugar transporter subunit IIB gene gene3620 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18180 UM146_RS18185 UM146_17555 gatC gatC 3629345 3630703 + PTS galactitol transporter subunit IIC with GatAB forms a phosphoenolpyruvate-dependent sugar phosphotransferase transporter for galactitol%3B subunit IIC forms the translocation channel and contains the substrate binding site gene gene3621 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18185 UM146_RS18190 UM146_17560 UM146_RS18190 3630696 3632204 + carbohydrate kinase gene gene3622 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18190 UM146_RS18195 UM146_17565 UM146_RS18195 3632194 3632463 + phosphocarrier protein HPr gene gene3623 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18195 UM146_RS18200 UM146_17570 gatY gatY 3632495 3633346 + fructose-bisphosphate aldolase class II aldolase%3B catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle%2C glycolysis and gluconeogenesis gene gene3624 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18200 UM146_RS18205 UM146_17575 UM146_RS18205 3633456 3634580 - inner membrane transport permease YhhJ gene gene3625 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18205 UM146_RS18210 UM146_17580 UM146_RS18210 3634580 3637315 - multidrug ABC transporter ATP-binding protein gene gene3626 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18210 UM146_RS18215 UM146_17585 UM146_RS18215 3637312 3638379 - membrane protein gene gene3627 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18215 UM146_RS18220 UM146_17590 UM146_RS18220 3639113 3640165 + membrane protein gene gene3628 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18220 UM146_RS18225 UM146_17595 UM146_RS18225 3640252 3641445 - membrane protein gene gene3629 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18225 UM146_RS18230 UM146_17600 UM146_RS18230 3641677 3643176 + Low-affinity inorganic phosphate transporter 1 involved in the transport of inorganic phosphate gene gene3630 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18230 UM146_RS18235 UM146_17605 UM146_RS18235 3643247 3643582 - universal stress protein B ppGpp-dependent%2C membrane associated%2C stress protein produced under conditions of nutrient deprivation%2C osmotic shock and oxidative stress gene gene3631 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18235 UM146_RS18240 UM146_17610 UM146_RS18240 3643973 3644407 + universal stress protein A involved in resistance to DNA-damaging agents gene gene3632 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18240 UM146_RS18245 UM146_17615 tppB tppB 3644724 3646193 + MFS transporter mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium%3B member of proton-dependent oligopeptide transport (POT) system family%3B in Escherichia coli this gene is regulated by OmpR although not via osmoregulation gene gene3633 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18245 UM146_RS18250 UM146_17620 UM146_RS18250 3646242 3646994 - ribosomal RNA small subunit methyltransferase J predicted SAM-dependent methyltransferase gene gene3634 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18250 UM146_RS18255 UM146_17625 UM146_RS18255 3647002 3649044 - oligopeptidase A gene gene3635 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18255 UM146_RS18260 UM146_17630 UM146_RS18260 3649247 3650089 + hypothetical protein gene gene3636 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18260 UM146_RS18265 UM146_17635 UM146_RS18265 3650161 3651513 + glutathione reductase catalyzes the reduction of 2 glutathione to glutathione disulfide%3B maintains high levels of reduced glutathione in the cytosol%3B involved in redox regulation and oxidative defense gene gene3637 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18265 UM146_RS18270 UM146_RS18270 UM146_RS18270 3651567 3651683 - hypothetical protein gene gene3638 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18270 UM146_RS18275 UM146_RS18275 UM146_RS18275 3651678 3651851 + hypothetical protein gene gene3639 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18275 UM146_RS18280 UM146_17640 UM146_RS18280 3652183 3652608 + arsenate reductase gene gene3640 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18280 UM146_RS18285 UM146_17645 UM146_RS18285 3653792 3654358 + outer membrane protein slp gene gene3641 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18285 UM146_RS18290 UM146_17650 UM146_RS18290 3654511 3655041 + transcriptional regulator gene gene3642 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18290 UM146_RS18295 UM146_17655 UM146_RS18295 3655098 3656126 - hemin transporter gene gene3643 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18295 UM146_RS18300 UM146_17660 UM146_RS18300 3656175 3658157 - ligand-gated channel protein gene gene3644 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18300 UM146_RS18305 UM146_RS18305 UM146_RS18305 3658063 3658254 + hypothetical protein gene gene3645 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18305 UM146_RS18310 UM146_17665 UM146_RS18310 3658841 3659755 + ABC transporter substrate-binding protein gene gene3646 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18310 UM146_RS18315 UM146_17670 UM146_RS18315 3659775 3661112 + heme utilization radical SAM enzyme HutW catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III gene gene3647 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18315 UM146_RS18320 UM146_17675 UM146_RS18320 3661125 3661619 + heme utilization carrier protein gene gene3648 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18320 UM146_RS18325 UM146_17680 UM146_RS18325 3661619 3662242 + hypothetical protein gene gene3649 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18325 UM146_RS18330 UM146_17685 UM146_RS18330 3662291 3663283 + permease of iron compound ABC transporter gene gene3650 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18330 UM146_RS18335 UM146_17690 hmuV hmuV 3663280 3664050 + hemin import ATP-binding protein HmuV with HmuTU is involved in the transport of hemin gene gene3651 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18335 UM146_RS18340 UM146_17695 UM146_RS18340 3664102 3664749 - magnesium transporter ATPase gene gene3652 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18340 UM146_RS18345 UM146_17700 hdeB hdeB 3664813 3665139 - acid stress chaperone HdeB gene gene3653 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18345 UM146_RS18350 UM146_17705 UM146_RS18350 3665255 3665587 - acid-resistance protein HdeA inactive form gene gene3654 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18350 UM146_RS18355 UM146_17710 UM146_RS18355 3665842 3666414 + acid-resistance protein HdeD gene gene3655 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18355 UM146_RS18360 UM146_17715 UM146_RS18360 3667213 3667740 + transcriptional regulator GadE gene gene3656 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18360 UM146_RS18365 UM146_RS18365 UM146_RS18365 3667690 3668019 - hypothetical protein gene gene3657 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18365 UM146_RS18370 UM146_17720 UM146_RS18370 3668079 3669236 + multidrug resistance protein MdtE gene gene3658 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18370 UM146_RS18375 UM146_17725 UM146_RS18375 3669261 3672374 + multidrug efflux RND transporter permease subunit gene gene3659 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18375 UM146_RS18380 UM146_17730 UM146_RS18380 3672737 3673465 - transcriptional regulator gene gene3660 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18380 UM146_RS18385 UM146_17735 UM146_RS18385 3673834 3674658 - transcriptional regulator regulates genes in response to acid and/or during stationary phase gene gene3661 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18385 UM146_RS18390 UM146_17740 UM146_RS18390 3675026 3676426 - glutamate decarboxylase alpha gene gene3662 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18390 UM146_RS18395 UM146_17745 UM146_RS18395 3676637 3678034 - cytochrome C peroxidase gene gene3663 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18395 UM146_RS18400 UM146_17750 treF treF 3678439 3680088 + trehalase cytoplasmic%3B catalyzes the hydrolysis of trehalose to glucose gene gene3664 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18400 UM146_RS18405 UM146_17755 UM146_RS18405 3680139 3680741 - LuxR family transcriptional regulator gene gene3665 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18405 UM146_RS18410 UM146_17760 UM146_RS18410 3681261 3682160 + LysR family transcriptional regulator gene gene3666 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18410 UM146_RS18415 UM146_17765 UM146_RS18415 3682209 3683222 + membrane protein gene gene3667 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18415 UM146_RS18420 UM146_17770 UM146_RS18420 3683615 3684937 + transporter gene gene3668 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18420 UM146_RS18425 UM146_17775 UM146_RS18425 3684978 3687038 - hypothetical protein gene gene3669 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18425 UM146_RS18430 UM146_17780 UM146_RS18430 3687108 3687875 - cyclic di-GMP phosphodiesterase in Escherichia coli this protein is involved in flagellar function gene gene3670 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18430 UM146_RS18435 UM146_RS18435 UM146_RS18435 3687829 3688023 + hypothetical protein gene gene3671 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18435 UM146_RS18440 UM146_17785 UM146_RS18440 3688107 3689036 + 2-dehydro-3-deoxygluconokinase catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate-6-phosphate from 2-dehydro-3-deoxy-D-gluconate gene gene3672 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18440 UM146_RS18445 UM146_17790 UM146_RS18445 3689132 3690628 - hypothetical protein gene gene3673 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18445 UM146_RS18450 UM146_17795 UM146_RS18450 3690848 3692134 - C4-dicarboxylate ABC transporter involved in the transport of C4-dicarboxylates across the membrane gene gene3674 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18450 UM146_RS18455 UM146_17800 UM146_RS18455 3692317 3694272 - biofilm formation regulator HmsP HmsP in Yersinia pestis plays a role in invasion of epithelial cells%3B the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation%3B inner membrane protein gene gene3675 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18455 UM146_RS18460 UM146_17805 UM146_RS18460 3694387 3697860 - cellulose synthase subunit BcsC cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium%3B the cellulose biosynthesis genes bcsA%2C bcsB%2C bcsZ and bcsC are constitutively transcribed%2C however%2C cellulose synthesis is dependent on the expression of adrA gene gene3676 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18460 UM146_RS18465 UM146_17810 UM146_RS18465 3697842 3698948 - endonuclease III catalyzes the hydrolysis of 1%2C4-beta-D-glucosidic linkages in cellulose%2C lichenin and cereal beta-D-glucans gene gene3677 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18465 UM146_RS18470 UM146_17815 UM146_RS18470 3698955 3701294 - cyclic di-GMP regulator CdgR binds the cellulose synthase activator%2C bis-(3'-5') cyclic diguanylic acid (c-di-GMP) gene gene3678 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18470 UM146_RS18475 UM146_17820 bcsA bcsA 3701305 3703923 - cellulose synthase catalytic subunit polymerizes uridine 5'-diphosphate glucose to cellulose%3B acts with BcsB%2C BcsZ and BcsC in cellulose biosynthesis gene gene3679 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18475 UM146_RS18480 UM146_17825 UM146_RS18480 3703920 3704672 - cell division protein gene gene3680 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18480 UM146_RS18485 UM146_17830 UM146_RS18485 3704684 3704872 - hypothetical protein gene gene3681 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18485 UM146_RS18490 UM146_17835 UM146_RS18490 3705157 3706716 + cellulose biosynthesis protein BcsE required for cellulose biosynthesis gene gene3682 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18490 UM146_RS18495 UM146_17840 UM146_RS18495 3706713 3706904 + protein BcsF gene gene3683 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18495 UM146_RS18500 UM146_17845 UM146_RS18500 3706901 3708580 + membrane protein gene gene3684 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18500 UM146_RS18505 UM146_RS18505 UM146_RS18505 3708666 3708833 - hypothetical protein gene gene3685 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18505 UM146_RS18510 UM146_RS18510 UM146_RS18510 3709149 3709316 - Small toxic polypeptide ldrD gene gene3686 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18510 UM146_RS18515 UM146_RS18515 UM146_RS18515 3709631 3709798 - Small toxic polypeptide ldrD gene gene3687 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18515 UM146_RS18520 UM146_RS18520 UM146_RS18520 3709903 3710064 - hypothetical protein gene gene3688 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18520 UM146_RS18525 UM146_17865 UM146_RS18525 3710214 3711485 + transporter gene gene3689 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18525 UM146_RS18530 UM146_17870 dppF dppF 3711515 3712519 - peptide ABC transporter ATP-binding protein Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides gene gene3690 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18530 UM146_RS18535 UM146_17875 dppD dppD 3712516 3713499 - peptide ABC transporter ATP-binding protein DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF gene gene3691 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18535 UM146_RS18540 UM146_17880 UM146_RS18540 3713510 3714412 - peptide ABC transporter permease gene gene3692 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18540 UM146_RS18545 UM146_17885 UM146_RS18545 3714422 3715441 - peptide ABC transporter permease gene gene3693 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18545 UM146_RS18550 UM146_RS18550 UM146_RS18550 3715459 3715602 + hypothetical protein gene gene3694 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18550 UM146_RS18555 UM146_17890 UM146_RS18555 3715592 3717199 - periplasmic dipeptide transporter DppABCDF is involved in the transport of dipeptides%3B also binds heme and mediates chemotaxis to dipeptides gene gene3695 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18555 UM146_RS18560 UM146_17895 UM146_RS18560 3717551 3717814 - hypothetical protein gene gene3696 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18560 UM146_RS18565 UM146_t23945 UM146_RS18565 3717943 3718019 - tRNA-Pro tRNA gene3697 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18565 UM146_RS18570 UM146_17900 UM146_RS18570 3718108 3719799 - phosphoethanolamine transferase catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide gene gene3698 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18570 UM146_RS18575 UM146_17905 UM146_RS18575 3720123 3721331 - membrane protein gene gene3699 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18575 UM146_RS18580 UM146_17910 UM146_RS18580 3721560 3722258 - hypothetical protein gene gene3700 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18580 UM146_RS18585 UM146_17915 UM146_RS18585 3722416 3722979 + DNA-3-methyladenine glycosylase gene gene3701 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18585 UM146_RS18590 UM146_17920 UM146_RS18590 3722976 3723416 + acetyltransferase gene gene3702 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18590 UM146_RS18595 UM146_17925 UM146_RS18595 3723385 3725664 - biotin sulfoxide reductase catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine gene gene3703 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18595 UM146_RS18600 UM146_17930 UM146_RS18600 3725871 3726530 + hypothetical protein gene gene3704 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18600 UM146_RS18605 UM146_17935 UM146_RS18605 3726634 3727608 + glyoxylate/hydroxypyruvate reductase B catalyzes the formation of glycolate from glyoxylate and glycerate from hydroxypyruvate gene gene3705 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18605 UM146_RS18610 UM146_17940 UM146_RS18610 3727658 3728368 - DUF3053 domain-containing protein gene gene3706 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18610 UM146_RS18615 UM146_17945 UM146_RS18615 3728802 3729092 + transcriptional regulator gene gene3707 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18615 UM146_RS18620 UM146_17950 UM146_RS18620 3729373 3729585 + cold-shock protein gene gene3708 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18620 UM146_RS18625 UM146_17955 UM146_RS18625 3729773 3729925 - protein HokA gene gene3709 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18625 UM146_RS18630 UM146_17960 glyS glyS 3730248 3732317 - glycine--tRNA ligase subunit beta glycine--tRNA ligase beta chain%3B glyS%3B class II aminoacyl tRNA synthetase%3B tetramer of alpha(2)beta(2)%3B catalyzes a two-step reaction%3B first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP%3B second by transfer of the aminoacyl-adenylate to its tRNA gene gene3710 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18630 UM146_RS18635 UM146_17965 UM146_RS18635 3732327 3733238 - glycine--tRNA ligase subunit alpha gene gene3711 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18635 UM146_RS18640 UM146_17970 UM146_RS18640 3733333 3733632 - membrane protein gene gene3712 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18640 UM146_RS18645 UM146_17975 UM146_RS18645 3733807 3734802 + O-acetyltransferase involved in enterobacterial common antigen biosynthesis%3B catalyzes the addition of O-acetyl groups to the N-acetyl-D-glucosamine residues of the trisaccharide repeat units of the enterobacterial common antigen gene gene3713 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18645 UM146_RS18650 UM146_17980 UM146_RS18650 3734844 3735281 - hypothetical protein gene gene3714 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18650 UM146_RS18655 UM146_17985 UM146_RS18655 3735327 3735668 - hypothetical protein gene gene3715 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18655 UM146_RS18660 UM146_17990 UM146_RS18660 3735837 3737291 - xylulokinase catalyzes the formation of D-xylulose-5-phosphate fro D-xylulose gene gene3716 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18660 UM146_RS18665 UM146_17995 UM146_RS18665 3737363 3738685 - xylose isomerase catalyzes the interconversion of D-xylose to D-xylulose gene gene3717 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18665 UM146_RS18670 UM146_18000 xylF xylF 3739051 3740043 + xylose ABC transporter substrate-binding protein periplasmic substrate-binding component of the ATP-dependent xylose transport system%3B high affinity gene gene3718 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18670 UM146_RS18675 UM146_18005 UM146_RS18675 3740121 3741662 + xylose import ATP-binding protein XylG with XylFH is part of the high affinity xylose ABC transporter gene gene3719 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18675 UM146_RS18680 UM146_18010 UM146_RS18680 3741640 3742821 + xylose ABC transporter permease gene gene3720 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18680 UM146_RS18685 UM146_18015 UM146_RS18685 3742899 3744077 + xylose operon regulatory protein gene gene3721 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18685 UM146_RS18690 UM146_RS18690 UM146_RS18690 3744185 3745009 - protein bax gene gene3722 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18690 UM146_RS18695 UM146_18025 malS malS 3745329 3747359 + alpha-amylase periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB%3B hydrolyzes alpha-(1%2C4) glycosidic linkages%3B contains internal disulfide bonds gene gene3723 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18695 UM146_RS18700 UM146_18030 avtA avtA 3747537 3748790 + valine--pyruvate aminotransferase transaminase C%3B catalyzes transamination of alanine%2C valine%2C and 2-aminobutyrate with their respective 2-keto acids%3B also catalyzes terminal step in valine biosynthesis gene gene3724 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18700 UM146_RS18705 UM146_RS18705 UM146_RS18705 3748794 3748922 + hypothetical protein gene gene3725 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18705 UM146_RS18710 UM146_18035 UM146_RS18710 3748942 3749415 - electron transporter gene gene3726 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18710 UM146_RS18715 UM146_18040 UM146_RS18715 3749517 3750365 - transcriptional regulator gene gene3727 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18715 UM146_RS18720 UM146_18045 UM146_RS18720 3750566 3751564 + 2%2C3-diketo-L-gulonate reductase NAD(P)H-dependent%3B catalyzes the reduction of 2%2C3-diketo-L-gulonate to 3-keto-L-gulonate gene gene3728 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18720 UM146_RS18725 UM146_18050 UM146_RS18725 3751576 3752040 + hypothetical protein gene gene3729 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18725 UM146_RS18730 UM146_18055 UM146_RS18730 3752063 3752983 + hypothetical protein gene gene3730 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18730 UM146_RS18735 UM146_18060 UM146_RS18735 3753097 3753564 + 2%2C3-diketo-L-gulonate TRAP transporter permease membrane-spanning protein involved in uptake of 2%2C3-diketo-L-gulonate%3B part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO gene gene3731 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18735 UM146_RS18740 UM146_18065 UM146_RS18740 3753567 3754844 + dehydroascorbate transporter TRAP family transporter%3B with YiaMO is involved in the uptake of L-dehydroascorbate gene gene3732 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18740 UM146_RS18745 UM146_RS18745 UM146_RS18745 3754857 3755842 + 2%2C3-diketo-L-gulonate TRAP transporter involved in the transport of 2%2C3-diketo-L-gulonate gene gene3733 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18745 UM146_RS18750 UM146_18080 UM146_RS18750 3755846 3757342 + L-xylulose/3-keto-L-gulonate kinase catalyzes the formation of L-xylulose 5-phosphate and 3-dehydro-L-gulonate 6-phosphate from L-xylulose or 3-dehydro-L-gulonate%2C respectively gene gene3734 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18750 UM146_RS18755 UM146_18085 sgbH sgbH 3757339 3758001 + 3-keto-L-gulonate-6-phosphate decarboxylase catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate gene gene3735 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18755 UM146_RS18760 UM146_18090 UM146_RS18760 3757994 3758854 + L-xylulose 5-phosphate 3-epimerase L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated%3B may be involved in the utilization of 2%2C3-diketo-L-gulonate gene gene3736 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18760 UM146_RS18765 UM146_18095 araD araD 3758848 3759543 + L-ribulose-5-phosphate 4-epimerase catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate%3B links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source gene gene3737 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18765 UM146_RS18770 UM146_18100 UM146_RS18770 3759590 3761128 - aldehyde dehydrogenase catalyzes the oxidation of acetaldehyde%2C benzaldehyde%2C propionaldehyde and other aldehydes gene gene3738 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18770 UM146_RS18775 UM146_18105 UM146_RS18775 3761236 3762531 - hypothetical protein gene gene3739 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18775 UM146_RS18780 UM146_18110 UM146_RS18780 3762661 3763812 - alcohol dehydrogenase gene gene3740 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18780 UM146_RS18785 UM146_18115 UM146_RS18785 3764003 3765847 - selenocysteine-specific translation elongation factor gene gene3741 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18785 UM146_RS18790 UM146_18120 UM146_RS18790 3765844 3767235 - L-seryl-tRNA(Sec) selenium transferase catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis gene gene3742 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18790 UM146_RS18795 UM146_18125 UM146_RS18795 3767333 3767941 - glutathione S-transferase gene gene3743 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18795 UM146_RS18800 UM146_18130 UM146_RS18800 3768012 3769148 - membrane protein gene gene3744 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18800 UM146_RS18805 UM146_18135 UM146_RS18805 3769151 3769513 - hypothetical protein gene gene3745 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18805 UM146_RS18810 UM146_18140 UM146_RS18810 3770049 3771962 + PTS mannitol transporter subunit IIABC catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B subunit IIC forms the translocation channel and contains the specific substrate-binding site%3B subunit IIA is phosphorylated and transfers the phosphoryl group to the IIB subunit%3B subunit IIB transfers the phosphoryl group to the substrate gene gene3746 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18810 UM146_RS18820 UM146_18145 UM146_RS18820 3772281 3773429 + mannitol-1-phosphate 5-dehydrogenase gene gene3747 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18820 UM146_RS18825 UM146_18150 UM146_RS18825 3773426 3774016 + hypothetical protein gene gene3748 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18825 UM146_RS18830 UM146_18155 UM146_RS18830 3774027 3774236 - hypothetical protein gene gene3749 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18830 UM146_RS18835 UM146_18160 UM146_RS18835 3774520 3774882 + DUF2810 domain-containing protein gene gene3750 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18835 UM146_RS18840 UM146_RS18840 UM146_RS18840 3775441 3776154 + hypothetical protein gene gene3751 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18840 UM146_RS18845 UM146_18175 UM146_RS18845 3776167 3780918 + adhesin gene gene3752 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18845 UM146_RS18850 UM146_18180 UM146_RS18850 3781328 3782983 + L-lactate permease gene gene3753 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18850 UM146_RS18855 UM146_18185 UM146_RS18855 3782983 3783759 + transcriptional regulator represses the lctPRD operon gene gene3754 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18855 UM146_RS18860 UM146_18190 lldD lldD 3783756 3784946 + lactate dehydrogenase flavin mononucleotide-dependent dehydrogenase%3B functions in aerobic respiration and also has a role in anaerobic nitrate respiration gene gene3755 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18860 UM146_RS18865 UM146_18195 UM146_RS18865 3784994 3785467 + tRNA (cytidine(34)-2'-O)-methyltransferase member of the SPOUT superfamily of RNA methyltransferases gene gene3756 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18865 UM146_RS18870 UM146_18200 cysE cysE 3785522 3786343 - serine acetyltransferase catalyzes the O-acetylation of serine gene gene3757 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18870 UM146_RS18875 UM146_18205 UM146_RS18875 3786423 3787442 - glycerol-3-phosphate dehydrogenase [NAD(P)+] gene gene3758 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18875 UM146_RS18880 UM146_18210 UM146_RS18880 3787442 3787909 - protein-export protein SecB molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm%3B in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA gene gene3759 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18880 UM146_RS18885 UM146_18215 UM146_RS18885 3787973 3788224 - glutaredoxin gene gene3760 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18885 UM146_RS18890 UM146_18220 UM146_RS18890 3788365 3788796 - hypothetical protein gene gene3761 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18890 UM146_RS18895 UM146_18225 UM146_RS18895 3789041 3790585 + 2%2C3-bisphosphoglycerate-independent phosphoglycerate mutase catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gene gene3762 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18895 UM146_RS18900 UM146_18230 UM146_RS18900 3790595 3791878 + peptidase M37 gene gene3763 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18900 UM146_RS18905 UM146_18235 UM146_RS18905 3791882 3792841 + hypothetical protein gene gene3764 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18905 UM146_RS18910 UM146_18240 UM146_RS18910 3792828 3793862 - glycosyl transferase gene gene3765 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18910 UM146_RS18915 UM146_18245 tdh tdh 3794101 3795126 - L-threonine 3-dehydrogenase converts threonine and NAD to 1%2C2-amino-3-oxobutanoate and NADH%3B functions in threonine catabolism gene gene3766 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18915 UM146_RS18920 UM146_18250 UM146_RS18920 3795136 3796332 - 2-amino-3-ketobutyrate CoA ligase catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine gene gene3767 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18920 UM146_RS18925 UM146_18255 rfaD rfaD 3796546 3797478 + ADP-L-glycero-D-manno-heptose-6-epimerase catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose gene gene3768 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18925 UM146_RS18930 UM146_18260 UM146_RS18930 3797488 3798534 + ADP-heptose--LPS heptosyl transferase catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core gene gene3769 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18930 UM146_RS18935 UM146_18265 UM146_RS18935 3798538 3799518 + ADP-heptose--LPS heptosyl transferase gene gene3770 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18935 UM146_RS18940 UM146_18270 UM146_RS18940 3799588 3800550 - polymerase gene gene3771 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18940 UM146_RS18945 UM146_RS18945 UM146_RS18945 3800886 3801868 - beta1%2C3-glucosyltransferase gene gene3772 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18945 UM146_RS18950 UM146_18285 UM146_RS18950 3801950 3802978 - UDP-galactose--(galactosyl) LPS alpha1%2C2-galactosyltransferase gene gene3773 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18950 UM146_RS18955 UM146_18290 UM146_RS18955 3803004 3803696 - LPS core heptose(II) kinase RfaY gene gene3774 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18955 UM146_RS18960 UM146_18295 UM146_RS18960 3803706 3804701 - LPS 1%2C2-glucosyltransferase gene gene3775 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18960 UM146_RS18965 UM146_18300 UM146_RS18965 3804718 3805734 - LPS 1%2C3-galactosyltransferase gene gene3776 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18965 UM146_RS18970 UM146_18305 UM146_RS18970 3805750 3806547 - LPS core heptose(I) kinase RfaP catalyzes the phosphorylation of heptose I in the lipopolysaccharide core gene gene3777 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18970 UM146_RS18975 UM146_18310 UM146_RS18975 3806540 3807664 - glucosyltransferase catalyzes the addition of the first glucose residue to the LPS core gene gene3778 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18975 UM146_RS18980 UM146_18315 UM146_RS18980 3807661 3808683 - LPS core heptosyltransferase RfaQ catalyzes the transfer of heptose(III) to heptose(II) in the lipopolysaccharide inner core gene gene3779 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18980 UM146_RS18985 UM146_18320 UM146_RS18985 3809132 3810409 + 3-deoxy-D-manno-octulosonic acid transferase catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A gene gene3780 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18985 UM146_RS18990 UM146_18325 coaD coaD 3810417 3810896 + phosphopantetheine adenylyltransferase Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA gene gene3781 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18990 UM146_RS18995 UM146_18330 UM146_RS18995 3810935 3811744 - formamidopyrimidine-DNA glycosylase Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases gene gene3782 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS18995 UM146_RS19000 UM146_18335 rpmG rpmG 3811842 3812009 - 50S ribosomal protein L33 in Escherichia coli BM108%2C a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function%3B there are paralogous genes in several bacterial genomes%2C and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31%3B the proteins in this group lack the CXXC motif gene gene3783 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19000 UM146_RS19005 UM146_18340 rpmB rpmB 3812030 3812266 - 50S ribosomal protein L28 required for 70S ribosome assembly gene gene3784 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19005 UM146_RS19010 UM146_18345 UM146_RS19010 3812483 3813151 - hypothetical protein gene gene3785 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19010 UM146_RS19015 UM146_18350 UM146_RS19015 3813323 3814543 + phosphopantothenoylcysteine decarboxylase catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine%2C which is then decarboxylated to form 4'-phosphopantotheine gene gene3786 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19015 UM146_RS19020 UM146_18355 UM146_RS19020 3814521 3814979 + deoxyuridine 5'-triphosphate nucleotidohydrolase catalyzes the formation of dUMP from dUTP gene gene3787 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19020 UM146_RS19025 UM146_18360 slmA slmA 3815086 3815682 + nucleoid occlusion factor SlmA FtsZ binding protein%3B synthetically lethal with a defect in the Min system%3B this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly gene gene3788 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19025 UM146_RS19030 UM146_18365 pyrE pyrE 3815719 3816360 - orotate phosphoribosyltransferase involved in fifth step of pyrimidine biosynthesis%3B converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate gene gene3789 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19030 UM146_RS19035 UM146_18370 rph rph 3816426 3817142 - ribonuclease PH RNase PH%3B tRNA nucleotidyltransferase%3B forms hexamers in Bacillus subtilis%3B phosphoroltic 3'-5' exoribonuclease%3B involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs gene gene3790 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19035 UM146_RS19040 UM146_18375 UM146_RS19040 3817269 3818132 + hypothetical protein gene gene3791 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19040 UM146_RS19045 UM146_18380 dinD dinD 3818354 3819178 + DNA damage-inducible protein D gene gene3792 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19045 UM146_RS19050 UM146_18385 UM146_RS19050 3819470 3820087 + hypothetical protein gene gene3793 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19050 UM146_RS19055 UM146_18390 ligB ligB 3820084 3821766 - DNA ligase B this ligase is similar to LigA but it lacks the C-terminal BRCT domain%3B catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ gene gene3794 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19055 UM146_RS19060 UM146_18395 gmk gmk 3822024 3822648 + guanylate kinase Essential for recycling GMP and indirectly%2C cGMP gene gene3795 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19060 UM146_RS19065 UM146_18400 rpoZ rpoZ 3822703 3822978 + DNA-directed RNA polymerase subunit omega Promotes RNA polymerase assembly%3B latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits gene gene3796 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19065 UM146_RS19070 UM146_18405 UM146_RS19070 3822997 3825105 + bifunctional (p)ppGpp synthetase II/ guanosine-3'%2C5'-bis pyrophosphate 3'-pyrophosphohydrolase gene gene3797 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19070 UM146_RS19075 UM146_18410 UM146_RS19075 3825112 3825801 + tRNA methyltransferase specifically modifies tRNA at position G18 gene gene3798 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19075 UM146_RS19080 UM146_18415 UM146_RS19080 3825807 3827888 + ATP-dependent DNA helicase RecG catalyzes branch migration in Holliday junction intermediates gene gene3799 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19080 UM146_RS19085 UM146_18420 UM146_RS19085 3827922 3829127 - sodium/glutamate symport carrier protein is involved with the sodium-dependent uptake of glutamate gene gene3800 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19085 UM146_RS19090 UM146_18425 UM146_RS19090 3829407 3830798 + xanthine permease XanP high-affinity transporter for xanthine gene gene3801 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19090 UM146_RS19095 UM146_18430 UM146_RS19095 3830919 3832628 + hypothetical protein gene gene3802 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19095 UM146_RS19100 UM146_18435 UM146_RS19100 3832672 3833352 - D-lyxose isomerase gene gene3803 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19100 UM146_RS19105 UM146_18440 UM146_RS19105 3833333 3834265 - fructokinase gene gene3804 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19105 UM146_RS19110 UM146_18445 UM146_RS19110 3834313 3835173 - hypothetical protein gene gene3805 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19110 UM146_RS19115 UM146_18450 UM146_RS19115 3835254 3836105 - aldolase gene gene3806 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19115 UM146_RS19120 UM146_18455 UM146_RS19120 3836117 3837208 - PTS fructose transporter subunit IIC gene gene3807 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19120 UM146_RS19125 UM146_18460 UM146_RS19125 3837233 3837547 - PTS fructose transporter subunit IIB gene gene3808 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19125 UM146_RS19130 UM146_18465 UM146_RS19130 3837565 3838035 - PTS fructose transporter subunit IIA gene gene3809 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19130 UM146_RS19135 UM146_18470 UM146_RS19135 3838062 3839615 - transcriptional regulator gene gene3810 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19135 UM146_RS19140 UM146_18475 UM146_RS19140 3839910 3842228 - alpha-glucosidase catalyzes the transfer of alpha-xylosyl residue gene gene3811 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19140 UM146_RS19145 UM146_18480 UM146_RS19145 3842238 3843620 - transporter may be involved in the transport of galactosides-pentoses-hexuronides gene gene3812 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19145 UM146_RS19150 UM146_t23947 UM146_RS19150 3843913 3844007 + tRNA-Sec tRNA gene3813 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19150 UM146_RS19155 UM146_18485 UM146_RS19155 3844060 3845097 + 2-hydroxyacid dehydrogenase gene gene3814 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19155 UM146_RS19160 UM146_RS19160 UM146_RS19160 3845305 3845526 + hypothetical protein gene gene3815 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19160 UM146_RS19165 UM146_18495 UM146_RS19165 3845667 3846035 + hypothetical protein gene gene3816 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19165 UM146_RS19170 UM146_RS19170 UM146_RS19170 3846332 3847254 + hypothetical protein gene gene3817 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19170 UM146_RS19175 UM146_18510 UM146_RS19175 3847258 3848076 - methionine ABC transporter substrate-binding protein gene gene3818 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19175 UM146_RS19180 UM146_RS19180 UM146_RS19180 3848174 3848290 + hypothetical protein gene gene3819 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19180 UM146_RS19185 UM146_18515 UM146_RS19185 3848298 3848591 + hypothetical protein gene gene3820 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19185 UM146_RS19190 UM146_18520 nepI nepI 3848632 3849822 - purine ribonucleoside efflux pump NepI experimental results in Escherichia coli suggest that this gene encodes an inosine export protein%3B member of major facilitator superfamily%3B MFS gene gene3821 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19190 UM146_RS19195 UM146_18525 UM146_RS19195 3850033 3850485 - DUF1198 domain-containing protein gene gene3822 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19195 UM146_RS19200 UM146_18530 UM146_RS19200 3850538 3851950 - adenine permease involved in the transport or adenine gene gene3823 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19200 UM146_RS19205 UM146_18535 UM146_RS19205 3852047 3853813 + adenine deaminase catalyzes the formation of hypoxanthine from adenine%3B in E. coli this activity has been detected in mutant strains but not in wild type gene gene3824 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19205 UM146_RS19210 UM146_18540 uhpT uhpT 3853859 3855250 - hexose phosphate transporter cytoplasmic membrane protein that functions as a monomer%3B catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate gene gene3825 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19210 UM146_RS19215 UM146_18545 UM146_RS19215 3855388 3856707 - hypothetical protein membrane protein regulates uhpT expression gene gene3826 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19215 UM146_RS19220 UM146_18550 UM146_RS19220 3856717 3858219 - sensor histidine kinase Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph gene gene3827 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19220 UM146_RS19225 UM146_18555 UM146_RS19225 3858219 3858809 - transcriptional regulator response regulator in two-component regulatory system wtih UhpB%3B phosphorylated UhpA is a positive activator uhpT%2C a hexose phosphates transporter gene gene3828 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19225 UM146_RS19230 UM146_18560 UM146_RS19230 3858882 3859172 - acetolactate synthase isozyme 1 small subunit with IlvB catalyzes the formation of 2-acetolactate from pyruvate%2C the small subunit is required for full activity and valine sensitivity%3B E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates%2C valine sensitivity and affinity for cofactors%3B also known as acetolactate synthase small subunit gene gene3829 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19230 UM146_RS19235 UM146_18565 UM146_RS19235 3859176 3860864 - acetolactate synthase gene gene3830 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19235 UM146_RS19240 UM146_RS19240 UM146_RS19240 3860970 3861068 - IlvB leader peptide gene gene3831 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19240 UM146_RS19245 UM146_18570 emrD emrD 3861469 3862653 + multidrug resistance protein D multidrug efflux protein involved in adaptation to low energy shock gene gene3832 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19245 UM146_RS19250 UM146_18575 UM146_RS19250 3862661 3863158 - hypothetical protein gene gene3833 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19250 UM146_RS19255 UM146_18580 UM146_RS19255 3863155 3863517 - hypothetical protein gene gene3834 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19255 UM146_RS19260 UM146_18585 UM146_RS19260 3863507 3863854 - hypothetical protein gene gene3835 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19260 UM146_RS19265 UM146_RS19265 UM146_RS19265 3863914 3865406 - hypothetical protein gene gene3836 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19265 UM146_RS19270 UM146_18600 UM146_RS19270 3865403 3867118 - AraC family transcriptional regulator uncharacterized member of the SSS superfamily of sodium-dependent solute transporters%3B unknown function gene gene3837 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19270 UM146_RS19275 UM146_18605 UM146_RS19275 3867285 3868151 + AraC family transcriptional regulator gene gene3838 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19275 UM146_RS19280 UM146_18610 UM146_RS19280 3868241 3869902 - transporter gene gene3839 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19280 UM146_RS19285 UM146_18615 UM146_RS19285 3869944 3870102 + peptide ABC transporter ATP-binding protein gene gene3840 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19285 UM146_RS19290 UM146_18620 UM146_RS19290 3870099 3870527 - heat-shock protein IbpB 16 kDa heat shock protein B%3B associates with aggregated proteins%2C together with ibpA%2C to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress%3B ATP-independent gene gene3841 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19290 UM146_RS19295 UM146_18625 UM146_RS19295 3870639 3871052 - heat-shock protein IbpA with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress gene gene3842 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19295 UM146_RS19300 UM146_18630 UM146_RS19300 3871430 3871690 + hypothetical protein gene gene3843 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19300 UM146_RS19305 UM146_18635 UM146_RS19305 3871694 3872908 - hypothetical protein gene gene3844 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19305 UM146_RS19310 UM146_18640 UM146_RS19310 3873009 3874109 + protein CbrA FAD/NAD(P)-binding domain gene gene3845 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19310 UM146_RS19315 UM146_18645 UM146_RS19315 3874070 3875362 - D-galactonate transporter gene gene3846 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19315 UM146_RS19320 UM146_18650 UM146_RS19320 3875482 3876630 - D-galactonate dehydratase gene gene3847 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19320 UM146_RS19325 UM146_18655 UM146_RS19325 3876627 3877244 - 2-dehydro-3-deoxy-6-phosphogalactonate aldolase catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate%3B functions in galactonate metabolism gene gene3848 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19325 UM146_RS19330 UM146_18660 UM146_RS19330 3877228 3878106 - 2-oxo-3-deoxygalactonate kinase catalyzes the formation of 2-dehydro-3-deoxy-D-galactonate 6-phosphate from 2-dehydro-3-deoxy-D-galactonate gene gene3849 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19330 UM146_RS19335 UM146_18665 UM146_RS19335 3878103 3878792 - transcriptional regulator gene gene3850 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19335 UM146_RS19340 UM146_18670 UM146_RS19340 3879071 3879727 + hypothetical protein gene gene3851 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19340 UM146_RS19345 UM146_18675 UM146_RS19345 3879771 3880583 - sugar phosphatase YidA YidA%3B catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate)%2C mannose 1-phosphate and p-nitrophenyl phosphate%3B hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form%3B member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins gene gene3852 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19345 UM146_RS19350 UM146_18680 UM146_RS19350 3880698 3881096 - hypothetical protein gene gene3853 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19350 UM146_RS19355 UM146_RS19355 UM146_RS19355 3881116 3881316 - hypothetical protein gene gene3854 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19355 UM146_RS19360 UM146_18685 gyrB gyrB 3881336 3883750 - DNA gyrase subunit B negatively supercoils closed circular double-stranded DNA gene gene3855 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19360 UM146_RS19365 UM146_18690 recF recF 3883779 3884852 - DNA recombination protein RecF Required for DNA replication%3B binds preferentially to single-stranded%2C linear DNA gene gene3856 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19365 UM146_RS19370 UM146_18695 UM146_RS19370 3884852 3885952 - DNA polymerase III subunit beta binds the polymerase to DNA and acts as a sliding clamp gene gene3857 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19370 UM146_RS19375 UM146_18700 dnaA dnaA 3885957 3887360 - chromosomal replication initiator protein DnaA binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication%3B can also affect transcription of multiple genes including itself. gene gene3858 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19375 UM146_RS19380 UM146_18705 rpmH rpmH 3887967 3888107 + 50S ribosomal protein L34 in Escherichia coli transcription of this gene is enhanced by polyamines gene gene3859 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19380 UM146_RS19385 UM146_18710 rnpA rnpA 3888124 3888483 + ribonuclease P protein component protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus%3B this enzyme also cleaves other RNA substrates gene gene3860 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19385 UM146_RS19390 UM146_18715 UM146_RS19390 3888447 3888704 + membrane protein insertion efficiency factor YidD gene gene3861 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19390 UM146_RS19395 UM146_18720 UM146_RS19395 3888707 3890353 + protein translocase component YidC functions to insert inner membrane proteins into the IM in Escherichia coli%3B interacts with transmembrane segments%3B functions in both Sec-dependent and -independent membrane insertion%3B similar to Oxa1p in mitochondria gene gene3862 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19395 UM146_RS19400 UM146_18725 trmE trmE 3890459 3891823 + tRNA modification GTPase MnmE in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine%2C which is found in the wobble position of some tRNAs and affects ribosomal frameshifting%3B shows potassium-dependent dimerization and GTP hydrolysis%3B also involved in regulation of glutamate-dependent acid resistance and activation of gadE gene gene3863 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19400 UM146_RS19405 UM146_RS19405 UM146_RS19405 3892065 3892139 + tryptophanase leader peptide gene gene3864 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19405 UM146_RS19410 UM146_18730 tnaA tnaA 3892360 3893775 + tryptophanase tryptophan indole-lyase%3B catalyzes the formation of indole and pyruvate from tryptophan%3B also has xysteine desulfhydrase activity gene gene3865 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19410 UM146_RS19415 UM146_18735 UM146_RS19415 3893867 3895114 + tryptophan permease tryptophan transporter of high affinity gene gene3866 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19415 UM146_RS19420 UM146_18740 UM146_RS19420 3895246 3896421 + multidrug resistance protein MdtL Confers resistance to chloramphenicol gene gene3867 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19420 UM146_RS19425 UM146_18745 UM146_RS19425 3896396 3897355 + transcriptional regulator Involved in anaerobic NO protection gene gene3868 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19425 UM146_RS19430 UM146_18750 UM146_RS19430 3897512 3898261 + hypothetical protein gene gene3869 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19430 UM146_RS19435 UM146_18755 UM146_RS19435 3898283 3898849 + chromate reductase gene gene3870 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19435 UM146_RS19440 UM146_18760 UM146_RS19440 3898902 3900239 - adenine permease involved in the transport or adenine gene gene3871 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19440 UM146_RS19445 UM146_RS19445 UM146_RS19445 3900406 3901076 + 6-phosphogluconate phosphatase YieH%3B catalyzes the dephosphorylation of phosphoenolpyruvate%2C AMP and p-nitrophenyl phosphate%3B purine and pyrimidine nucleotides are secondary substrates%3B member of the haloacid dehalogenase-like hydrolases superfamily gene gene3872 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19445 UM146_RS19450 UM146_18775 UM146_RS19450 3901143 3901616 + protein CbrB might be involved in hypersensitivity to nitrofurzone gene gene3873 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19450 UM146_RS19455 UM146_18780 UM146_RS19455 3901698 3902420 - 6-phosphogluconolactonase gene gene3874 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19455 UM146_RS19460 UM146_18785 UM146_RS19460 3902435 3903604 - hypothetical protein gene gene3875 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19460 UM146_RS19465 UM146_18790 UM146_RS19465 3903631 3905247 - porin gene gene3876 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19465 UM146_RS19470 UM146_18795 UM146_RS19470 3905333 3906727 - 6-phospho-beta-glucosidase gene gene3877 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19470 UM146_RS19475 UM146_18800 UM146_RS19475 3906746 3908620 - PTS beta-glucoside transporter subunit IIABC phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene3878 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19475 UM146_RS19480 UM146_18805 UM146_RS19480 3908753 3909589 - transcription antitermination protein BlgG positive regulator of the beta-glucoside operon%3B transcriptional antiterminator gene gene3879 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19480 UM146_RS19485 UM146_18810 UM146_RS19485 3909875 3910600 - transcriptional regulator regulates several genes involved in high affinity phosphate uptake%3B under conditions of high phosphate concentrations downregulates the PHO regulon gene gene3880 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19485 UM146_RS19490 UM146_18815 UM146_RS19490 3910615 3911388 - phosphate import ATP-binding protein PstB gene gene3881 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19490 UM146_RS19495 UM146_18820 pstA pstA 3911479 3912369 - phosphate transporter permease subunit PtsA Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions gene gene3882 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19495 UM146_RS19500 UM146_18825 pstC pstC 3912369 3913328 - phosphate ABC transporter permease part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions gene gene3883 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19500 UM146_RS19505 UM146_18830 UM146_RS19505 3913415 3914455 - phosphate-binding protein gene gene3884 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19505 UM146_RS19510 UM146_18835 UM146_RS19510 3914769 3916598 - glutamine--fructose-6-phosphate aminotransferase [isomerizing] Catalyzes the first step in hexosamine metabolism%2C converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source gene gene3885 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19510 UM146_RS19515 UM146_18840 glmU glmU 3916759 3918129 - bifunctional protein GlmU forms a homotrimer%3B catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc%3B function in cell wall synthesis gene gene3886 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19515 UM146_RS19520 UM146_18845 atpC atpC 3918483 3918902 - ATP synthase epsilon chain part of catalytic core of ATP synthase%3B alpha(3)beta(3)gamma(1)delta(1)epsilon(1)%3B involved in producing ATP from ADP in the presence of the proton motive force across the membrane gene gene3887 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19520 UM146_RS19525 UM146_18850 UM146_RS19525 3918923 3920305 - ATP synthase subunit beta gene gene3888 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19525 UM146_RS19530 UM146_18855 UM146_RS19530 3920332 3921195 - ATP synthase subunit gamma Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit gene gene3889 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19530 UM146_RS19535 UM146_18860 UM146_RS19535 3921246 3922787 - ATP synthase subunit alpha produces ATP from ADP in the presence of a proton gradient across the membrane%3B the alpha chain is a catalytic subunit gene gene3890 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19535 UM146_RS19540 UM146_18865 UM146_RS19540 3922800 3923333 - ATP synthase subunit delta Produces ATP from ADP in the presence of a proton gradient across the membrane%3B the delta subunit is part of the catalytic core of the ATP synthase complex gene gene3891 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19540 UM146_RS19545 UM146_18870 UM146_RS19545 3923348 3923818 - ATP synthase subunit b Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. gene gene3892 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19545 UM146_RS19550 UM146_18875 UM146_RS19550 3923880 3924119 - ATP synthase subunit c Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 gene gene3893 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19550 UM146_RS19555 UM146_18880 UM146_RS19555 3924166 3924981 - ATP synthase subunit a Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 gene gene3894 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19555 UM146_RS19560 UM146_18885 UM146_RS19560 3924990 3925370 - ATP synthase I Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation gene gene3895 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19560 UM146_RS19565 UM146_18890 gidB gidB 3925986 3926609 - ribosomal RNA small subunit methyltransferase G glucose-inhibited division protein B%3B SAM-dependent methyltransferase%3B methylates the N7 position of guanosine in position 527 of 16S rRNA gene gene3896 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19565 UM146_RS19570 UM146_18895 gidA gidA 3926673 3928562 - tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GidA%3B glucose-inhibited cell division protein A%3B involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs gene gene3897 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19570 UM146_RS19575 UM146_18900 UM146_RS19575 3928941 3929384 - FMN-binding protein MioC An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group gene gene3898 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19575 UM146_RS19580 UM146_18905 UM146_RS19580 3929474 3929932 - AsnC family transcriptional regulator transcriptional repressor of asnA which codes for aspartate-ammonia ligase gene gene3899 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19580 UM146_RS19585 UM146_18910 UM146_RS19585 3930084 3931076 + aspartate--ammonia ligase catalyzes the formation of asparagine from aspartate and ammonia gene gene3900 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19585 UM146_RS19590 UM146_18915 UM146_RS19590 3931081 3932532 - protein ViaA contains a von Willibrand factor type A domain%3B stimulates the ATPase activity of RavA gene gene3901 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19590 UM146_RS19595 UM146_18920 UM146_RS19595 3932526 3934022 - ATPase RavA interacts with LdcI%2C lysine decarboxylase%3B may be active in late log/ early stationary phase gene gene3902 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19595 UM146_RS19600 UM146_18925 trkD trkD 3934245 3936113 + low affinity potassium transport system protein kup Responsible for the low-affinity transport of potassium into the cell%3B involved in potassium ion uptake under hyper-osmotic stress at a low pH gene gene3903 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19600 UM146_RS19605 UM146_18930 UM146_RS19605 3936280 3936699 + D-ribose pyranase cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose%3B RbsD is required for efficient ribose utilization in E. coli%3B rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source gene gene3904 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19605 UM146_RS19610 UM146_18935 UM146_RS19610 3936707 3938212 + ribose import ATP-binding protein RbsA gene gene3905 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19610 UM146_RS19615 UM146_18940 rbsC rbsC 3938217 3939182 + ribose ABC transporter permease functions to transport ribose at high affinity%3B forms a complex with RbsA2C2B gene gene3906 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19615 UM146_RS19620 UM146_18945 UM146_RS19620 3939207 3940097 + D-ribose transporter subunit RbsB periplasmic substrate-binding component of the ATP-dependent ribose transport system gene gene3907 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19620 UM146_RS19625 UM146_18950 UM146_RS19625 3940223 3941152 + ribokinase catalyzes the formation of D-ribose 5-phosphate from ribose gene gene3908 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19625 UM146_RS19630 UM146_18955 UM146_RS19630 3941165 3942148 + LacI family transcriptional regulator binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis%3B is involved in regulation of purB%2C purC%2C purEK%2C purHD%2C purL%2C purMN and guaBA expression%3B binds hypoxanthine and guanine as inducers gene gene3909 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19630 UM146_RS19635 UM146_18960 UM146_RS19635 3942114 3943541 - transporter gene gene3910 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19635 UM146_RS19640 UM146_18965 UM146_RS19640 3943564 3944256 - GntR family transcriptional regulator gene gene3911 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19640 UM146_RS19645 UM146_r24011 UM146_RS19645 3944735 3946290 + 16S ribosomal RNA rRNA gene3912 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19645 UM146_RS19650 UM146_t23949 UM146_RS19650 3946364 3946439 + tRNA-Glu tRNA gene3913 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19650 UM146_RS19655 UM146_r24025 UM146_RS19655 3946624 3949548 + 23S ribosomal RNA rRNA gene3914 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19655 UM146_RS19660 UM146_r23999 UM146_RS19660 3949632 3949747 + 5S ribosomal RNA rRNA gene3915 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19660 UM146_RS19665 UM146_t23951 UM146_RS19665 3949801 3949877 + tRNA-Asp tRNA gene3916 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19665 UM146_RS19670 UM146_t23953 UM146_RS19670 3949886 3949961 + tRNA-Trp tRNA gene3917 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19670 UM146_RS19675 UM146_18970 UM146_RS19675 3950056 3950895 - transcriptional regulator Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon gene gene3918 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19675 UM146_RS19680 UM146_18975 UM146_RS19680 3951014 3951352 + hypothetical protein gene gene3919 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19680 UM146_RS19685 UM146_18980 UM146_RS19685 3951377 3952897 - ATP-dependent protease among the AAA+ ATPases%2C the YifB protease family belongs to the Helix 2 insert clade%3B unknown function gene gene3920 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19685 UM146_RS19690 UM146_RS19690 UM146_RS19690 3953250 3953348 + IlvGMEDA operon leader peptide gene gene3921 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19690 UM146_RS19695 UM146_18985 UM146_RS19695 3953488 3955134 + acetolactate synthase catalyzes the formation of 2-acetolactate from pyruvate%3B also known as acetolactate synthase large subunit gene gene3922 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19695 UM146_RS19700 UM146_18990 ilvM ilvM 3955131 3955394 + acetolactate synthase isozyme 2 small subunit gene gene3923 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19700 UM146_RS19705 UM146_18995 UM146_RS19705 3955414 3956343 + branched-chain amino acid aminotransferase gene gene3924 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19705 UM146_RS19710 UM146_19000 UM146_RS19710 3956408 3958258 + dihydroxy-acid dehydratase catalyzes the dehydration of 2%2C3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis gene gene3925 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19710 UM146_RS19715 UM146_19005 UM146_RS19715 3958258 3959805 + threonine dehydratase threonine deaminase%3B threonine dehydratase%3B in Escherichia coli%2C IlvA is part of the isoleucine biosynthetic pathway gene gene3926 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19715 UM146_RS19720 UM146_19010 UM146_RS19720 3959802 3960692 - transcriptional regulator participates in controlling several genes involved in isoleucine and valine biosynthesis%3B activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate gene gene3927 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19720 UM146_RS19725 UM146_19015 UM146_RS19725 3960842 3962317 + ketol-acid reductoisomerase catalyzes the formation of (R)-2%2C3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis gene gene3928 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19725 UM146_RS19730 UM146_19020 UM146_RS19730 3962363 3962644 - peptidyl-prolyl cis-trans isomerase rotamase C%3B accelerates isomerization of the peptidyl prolyl bond gene gene3929 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19730 UM146_RS19735 UM146_19025 UM146_RS19735 3962731 3964752 + ATP-dependent DNA helicase Rep single-stranded DNA-dependent ATPase%3B initiates unwinding at a nick in the DNA%3B involved in DNA replication gene gene3930 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19735 UM146_RS19740 UM146_19030 UM146_RS19740 3964799 3966283 - guanosine-5'-triphosphate%2C3'-diphosphate pyrophosphatase catalyzes the conversion of guanosine 5'-triphosphate%2C3'-diphosphate (pppGpp) to guanosine 5'-diphosphate%2C3'-diphosphate (ppGpp)%3B pppGpp and ppGpp control the stringent response during amino acid starvation gene gene3931 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19740 UM146_RS19745 UM146_19035 UM146_RS19745 3966419 3967684 - ATP-dependent RNA helicase RhlB enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome%2C a multi-enzyme complex important in RNA processing and messenger RNA degradation gene gene3932 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19745 UM146_RS19750 UM146_19040 trxA trxA 3967815 3968144 + thioredoxin gene gene3933 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19750 UM146_RS19755 UM146_19045 UM146_RS19755 3968285 3968386 + rho operon leader peptide gene gene3934 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19755 UM146_RS19760 UM146_19050 rho rho 3968471 3969730 + transcription termination factor Rho An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes gene gene3935 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19760 UM146_RS19765 UM146_19055 UM146_RS19765 3969740 3969865 + hypothetical protein gene gene3936 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19765 UM146_RS19770 UM146_19060 UM146_RS19770 3969970 3971073 + undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase catalyzes the formation of alpha-N-acetylglucosaminyl-pyrophosphoryl-undecaprenyl from alpha-N-acetylglucosaminyl 1-phosphate and the lipid carrier undecaprenyl phosphate gene gene3937 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19770 UM146_RS19775 UM146_19065 UM146_RS19775 3971085 3972131 + LPS biosynthesis protein Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein gene gene3938 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19775 UM146_RS19780 UM146_19070 UM146_RS19780 3972187 3973317 + UDP-N-acetylglucosamine 2-epimerase gene gene3939 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19780 UM146_RS19785 UM146_19075 wecC wecC 3973314 3974576 + UDP-N-acetyl-D-mannosamine dehydrogenase catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid gene gene3940 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19785 UM146_RS19790 UM146_19080 UM146_RS19790 3974576 3975643 + dTDP-glucose 4%2C6-dehydratase gene gene3941 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19790 UM146_RS19795 UM146_19085 UM146_RS19795 3975662 3976543 + glucose-1-phosphate thymidylyltransferase 2 gene gene3942 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19795 UM146_RS19800 UM146_19090 UM146_RS19800 3976521 3977195 + dTDP-fucosamine acetyltransferase gene gene3943 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19800 UM146_RS19805 UM146_19095 UM146_RS19805 3977200 3978330 + TDP-4-oxo-6-deoxy-D-glucose aminotransferase catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis gene gene3944 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19805 UM146_RS19810 UM146_19100 UM146_RS19810 3978332 3979582 + translocase involved in the movement of lipid III across the membrane gene gene3945 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19810 UM146_RS19815 UM146_19105 UM146_RS19815 3979579 3980658 + TDP-N-acetylfucosamine--lipid II N-acetylfucosaminyltransferase catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis gene gene3946 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19815 UM146_RS19820 UM146_19110 UM146_RS19820 3980655 3981914 + polymerase enterobacterial common antigen polymerase gene gene3947 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19820 UM146_RS19825 UM146_19115 UM146_RS19825 3982009 3982749 + UDP-N-acetyl-D-mannosaminuronic acid transferase gene gene3948 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19825 UM146_RS19830 UM146_19120 UM146_RS19830 3982940 3984325 + alanine glycine permease involved in the transport across the cytoplasmic membrane of D-alanine%2C D-serine and glycine gene gene3949 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19830 UM146_RS19835 UM146_t23955 UM146_RS19835 3984428 3984504 + tRNA-Arg tRNA gene3950 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19835 UM146_RS19840 UM146_t23957 UM146_RS19840 3984563 3984638 + tRNA-His tRNA gene3951 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19840 UM146_RS19845 UM146_t23959 UM146_RS19845 3984659 3984745 + tRNA-Leu tRNA gene3952 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19845 UM146_RS19850 UM146_t23961 UM146_RS19850 3984788 3984864 + tRNA-Pro tRNA gene3953 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19850 UM146_RS19855 UM146_19125 UM146_RS19855 3985011 3986246 + anaerobic sulfatase maturase AslB gene gene3954 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19855 UM146_RS19860 UM146_19130 UM146_RS19860 3986404 3988059 - arylsulfatase gene gene3955 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19860 UM146_RS19865 UM146_19135 UM146_RS19865 3988738 3989934 - heme biosynthesis protein HemY gene gene3956 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19865 UM146_RS19870 UM146_19140 UM146_RS19870 3989937 3991142 - uroporphyrinogen III methyltransferase gene gene3957 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19870 UM146_RS19875 UM146_19145 hemD hemD 3991164 3991904 - uroporphyrinogen III methyltransferase catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane%3B functions in tetrapyrrole and heme biosynthesis gene gene3958 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19875 UM146_RS19880 UM146_19150 hemC hemC 3991901 3992842 - porphobilinogen deaminase transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis gene gene3959 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19880 UM146_RS19885 UM146_19155 cyaA cyaA 3993229 3995775 + adenylate cyclase catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP gene gene3960 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19885 UM146_RS19890 UM146_19160 cyaY cyaY 3995815 3996135 - protein CyaY iron-dependent inhibitor of iron-sulfur cluster formation%3B iron-binding and oxidizing protein%3B defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease%3B based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly gene gene3961 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19890 UM146_RS19895 UM146_19165 UM146_RS19895 3996183 3997499 - hypothetical protein gene gene3962 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19895 UM146_RS19900 UM146_19170 UM146_RS19900 3997496 3998965 - hypothetical protein gene gene3963 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19900 UM146_RS19905 UM146_19175 UM146_RS19905 3999154 3999357 + membrane protein gene gene3964 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19905 UM146_RS19910 UM146_19180 dapF dapF 3999394 4000218 + diaminopimelate epimerase involved in lysine biosynthesis%3B DAP epimerase%3B produces DL-diaminopimelate from LL-diaminopimelate gene gene3965 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19910 UM146_RS19915 UM146_19185 UM146_RS19915 4000215 4000922 + hypothetical protein gene gene3966 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19915 UM146_RS19920 UM146_19190 xerC xerC 4000919 4001815 + tyrosine recombinase XerC site-specific tyrosine recombinase which cuts and rejoins DNA molecules%3B binds cooperatively to specific DNA consensus sites%3B forms a heterotetrameric complex with XerC%3B XerCD exhibit similar sequences%3B essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation%3B cell division protein FtsK may regulate the XerCD complex%3B enzyme from Streptococcus group has unusual active site motifs gene gene3967 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19920 UM146_RS19925 UM146_19195 UM146_RS19925 4001815 4002531 + flavin mononucleotide phosphatase YigB%3B member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein%3B unknown function gene gene3968 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19925 UM146_RS19930 UM146_19200 uvrD uvrD 4002615 4004777 + DNA-dependent helicase unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present%3B involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. gene gene3969 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19930 UM146_RS19935 UM146_19205 UM146_RS19935 4004822 4005724 - acetolactate synthase gene gene3970 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19935 UM146_RS19940 UM146_19210 UM146_RS19940 4005807 4006571 - hypothetical protein gene gene3971 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19940 UM146_RS19945 UM146_RS19945 UM146_RS19945 4006584 4006697 + hypothetical protein gene gene3972 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19945 UM146_RS19950 UM146_19215 UM146_RS19950 4006941 4007891 + magnesium transporter CorA responsible for the influx of magnesium ions gene gene3973 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19950 UM146_RS19955 UM146_19220 UM146_RS19955 4007927 4008424 - membrane protein gene gene3974 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19955 UM146_RS19960 UM146_19225 UM146_RS19960 4008421 4009268 - hypothetical protein gene gene3975 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19960 UM146_RS19965 UM146_19230 UM146_RS19965 4009579 4010469 - protein RarD gene gene3976 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19965 UM146_RS19970 UM146_19235 UM146_RS19970 4010521 4010988 - hypothetical protein gene gene3977 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19970 UM146_RS19975 UM146_19240 UM146_RS19975 4011153 4012022 + phospholipase A catalyzes the hydrolysis of phosphatidylcholine gene gene3978 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19975 UM146_RS19980 UM146_19245 UM146_RS19980 4012147 4013976 + ATP-dependent DNA helicase RecQ functions in blocking illegitimate recombination%2C enhancing topoisomerase activity%2C initiating SOS signaling and clearing blocked replication forks%3B component of the RecF recombinational pathway gene gene3979 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19980 UM146_RS19985 UM146_19250 UM146_RS19985 4014040 4014660 + threonine transporter RhtB gene gene3980 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19985 UM146_RS19990 UM146_19255 rhtB rhtB 4014721 4015341 - homoserine/homoserine lactone efflux protein gene gene3981 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19990 UM146_RS19995 UM146_19260 UM146_RS19995 4015452 4016474 + lysophospholipase L2 lecithinase B%3B catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine%3B can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates gene gene3982 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS19995 UM146_RS20000 UM146_19265 UM146_RS20000 4016482 4017282 + hydrolase gene gene3983 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20000 UM146_RS20005 UM146_19270 UM146_RS20005 4017358 4018257 + membrane protein gene gene3984 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20005 UM146_RS20010 UM146_19275 UM146_RS20010 4018145 4019098 - transcriptional regulator homocysteine-binding%3B positive regulator of metA%2C metE and metH gene gene3985 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20010 UM146_RS20015 UM146_19280 UM146_RS20015 4019216 4021477 + 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene3986 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20015 UM146_RS20020 UM146_19285 UM146_RS20020 4021646 4021891 - hypothetical protein gene gene3987 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20020 UM146_RS20025 UM146_19290 UM146_RS20025 4021966 4022223 - hypothetical protein gene gene3988 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20025 UM146_RS20030 UM146_RS20030 UM146_RS20030 4022220 4022909 - HNH endonuclease gene gene3989 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20030 UM146_RS20035 UM146_19300 UM146_RS20035 4022910 4023020 + hypothetical protein gene gene3990 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20035 UM146_RS20040 UM146_19310 UM146_RS20040 4023838 4024395 + 6-phospho 3-hexuloisomerase gene gene3991 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20040 UM146_RS20045 UM146_19315 UM146_RS20045 4024499 4025944 + PTS N-acetylglucosamine transporter subunit IICB phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene3992 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20045 UM146_RS20050 UM146_19320 UM146_RS20050 4025995 4027992 + transketolase catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate%3B can transfer ketol groups between several groups%3B in Escherichia coli there are two tkt genes%2C tktA expressed during exponential growth and the tktB during stationary phase gene gene3993 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20050 UM146_RS20055 UM146_RS20055 UM146_RS20055 4028022 4028866 - sugar isomerase gene gene3994 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20055 UM146_RS20060 UM146_19335 UM146_RS20060 4029067 4029972 - LysR family transcriptional regulator gene gene3995 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20060 UM146_RS20065 UM146_19340 UM146_RS20065 4030050 4031273 - permease gene gene3996 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20065 UM146_RS20070 UM146_19345 UM146_RS20070 4031299 4031688 - glutamyl-tRNA amidotransferase gene gene3997 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20070 UM146_RS20075 UM146_19350 UM146_RS20075 4031705 4032661 - carbamate kinase gene gene3998 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20075 UM146_RS20080 UM146_19355 UM146_RS20080 4032654 4034078 - hypothetical protein gene gene3999 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20080 UM146_RS20085 UM146_19360 UM146_RS20085 4034075 4035634 - hypothetical protein gene gene4000 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20085 UM146_RS20090 UM146_19365 UM146_RS20090 4035729 4036589 - hypothetical protein gene gene4001 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20090 UM146_RS20095 UM146_19370 UM146_RS20095 4036595 4037263 - cysteine hydrolase gene gene4002 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20095 UM146_RS20100 UM146_19375 UM146_RS20100 4037394 4037489 + hypothetical protein gene gene4003 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20100 UM146_RS20105 UM146_19380 UM146_RS20105 4037520 4038329 - carboxymethylenebutenolidase gene gene4004 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20105 UM146_RS20110 UM146_19385 UM146_RS20110 4038591 4039355 + uridine phosphorylase catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate%3B involved in the pyrimidine salvage pathway gene gene4005 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20110 UM146_RS20115 UM146_RS20115 UM146_RS20115 4039390 4040881 - C4-dicarboxylate ABC transporter permease gene gene4006 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20115 UM146_RS20120 UM146_19400 UM146_RS20120 4040894 4041400 - permease gene gene4007 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20120 UM146_RS20125 UM146_19405 UM146_RS20125 4041417 4042391 - ABC transporter substrate-binding protein gene gene4008 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20125 UM146_RS20130 UM146_19410 UM146_RS20130 4042416 4043045 - 2-dehydro-3-deoxy-6-phosphogalactonate aldolase gene gene4009 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20130 UM146_RS20135 UM146_19415 UM146_RS20135 4043035 4043814 - carbohydrate kinase gene gene4010 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20135 UM146_RS20140 UM146_19420 UM146_RS20140 4044063 4044830 - transcriptional regulator gene gene4011 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20140 UM146_RS20145 UM146_19425 UM146_RS20145 4045047 4046474 + DNA recombination protein RmuC YigN%3B nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence%3B transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner gene gene4012 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20145 UM146_RS20150 UM146_19430 ubiE ubiE 4046569 4047324 + ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone and menaquinone gene gene4013 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20150 UM146_RS20155 UM146_19435 UM146_RS20155 4047338 4047943 + membrane protein gene gene4014 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20155 UM146_RS20160 UM146_19440 ubiB ubiB 4047940 4049580 + hypothetical protein an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone%3B functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis%3B similar to eukaryotic proteins that exhibit kinase functions gene gene4015 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20160 UM146_RS20165 UM146_19445 tatA tatA 4049659 4049928 + protein translocase TatA TatA%3B similar to TatE that is found in some proteobacteria%3B part of system that translocates proteins with a conserved twin arginine motif across the inner membrane%3B capable of translocating folded substrates typically those with bound cofactors%3B similar to a protein import system in thylakoid membranes gene gene4016 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20165 UM146_RS20170 UM146_19450 UM146_RS20170 4049932 4050447 + Sec-independent protein translocase TatB mediates the export of protein precursors bearing twin-arginine signal peptides gene gene4017 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20170 UM146_RS20175 UM146_19455 UM146_RS20175 4050450 4051226 + preprotein translocase subunit TatC with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane gene gene4018 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20175 UM146_RS20180 UM146_19460 UM146_RS20180 4051268 4052050 + DNase TatD magnesium dependent%3B involved in quality control of mutated Tat exported substrates%3B not involved in the Sec-independent protein export system gene gene4019 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20180 UM146_RS20185 UM146_19465 rfaH rfaH 4052047 4052535 - transcription antitermination protein RfaH gene gene4020 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20185 UM146_RS20190 UM146_19470 UM146_RS20190 4052702 4054195 + 3-octaprenyl-4-hydroxybenzoate carboxy-lyase catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol gene gene4021 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20190 UM146_RS20195 UM146_19475 fre fre 4054241 4054942 + NAD(P)H-flavin reductase NAD(P)H-flavin reductase%3B catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide%3B in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin gene gene4022 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20195 UM146_RS20205 UM146_19480 fadA fadA 4055225 4056388 - 3-ketoacyl-CoA thiolase FadA%3B fatty acid oxidation complex component beta%3B functions in a heterotetramer with FadB%3B similar to FadI2J2 complex%3B functions in beta-oxidation of fatty acids gene gene4023 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20205 UM146_RS20210 UM146_19485 fadB fadB 4056398 4058587 - fatty acid oxidation complex subunit alpha includes enoyl-CoA hydratase%2C delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase%2C 3-hydroxyacyl-CoA dehydrogenase%2C and 3-hydroxybutyryl-CoA epimerase%3B catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA%3B also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities%3B forms a heterotetramer with FadA%3B similar to FadI2J2 complex%3B functions in beta-oxidation of fatty acids gene gene4024 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20210 UM146_RS20215 UM146_19490 UM146_RS20215 4058777 4060108 + Xaa-Pro dipeptidase catalyzes the hydrolysis of dipeptides with a proline at the C-terminal%3B also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters gene gene4025 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20215 UM146_RS20220 UM146_19495 UM146_RS20220 4060108 4060722 + hypothetical protein gene gene4026 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20220 UM146_RS20225 UM146_19500 UM146_RS20225 4060761 4062212 + potassium transporter gene gene4027 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20225 UM146_RS20230 UM146_19505 hemG hemG 4062224 4062769 + protoporphyrinogen IX dehydrogenase [menaquinone] catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX gene gene4028 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20230 UM146_RS20235 UM146_r24013 UM146_RS20235 4063143 4064698 + 16S ribosomal RNA rRNA gene4029 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20235 UM146_RS20240 UM146_t23963 UM146_RS20240 4064755 4064831 + tRNA-Ile tRNA gene4030 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20240 UM146_RS20245 UM146_t23965 UM146_RS20245 4064874 4064949 + tRNA-Ala tRNA gene4031 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20245 UM146_RS20250 UM146_r24027 UM146_RS20250 4065124 4068048 + 23S ribosomal RNA rRNA gene4032 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20250 UM146_RS20255 UM146_r24001 UM146_RS20255 4068132 4068247 + 5S ribosomal RNA rRNA gene4033 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20255 UM146_RS20260 UM146_19510 UM146_RS20260 4068350 4068877 - molybdopterin-guanine dinucleotide biosynthesis protein B in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway gene gene4034 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20260 UM146_RS20265 UM146_19515 mobA mobA 4068859 4069443 - molybdenum cofactor guanylyltransferase in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis gene gene4035 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20265 UM146_RS20270 UM146_19520 UM146_RS20270 4069513 4069782 + hypothetical protein gene gene4036 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20270 UM146_RS20275 UM146_19525 UM146_RS20275 4069859 4070845 + serine/threonine protein kinase catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro%3B specific substrate in vivo has not been identified yet%3B plays a role in long-term cell survival and expression of surface appendages gene gene4037 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20275 UM146_RS20280 UM146_19530 UM146_RS20280 4070862 4071488 + thiol:disulfide interchange protein DsbA gene gene4038 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20280 UM146_RS20285 UM146_19535 UM146_RS20285 4071643 4073073 + hypothetical protein gene gene4039 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20285 UM146_RS20290 UM146_19540 UM146_RS20290 4073114 4074046 - acyltransferase gene gene4040 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20290 UM146_RS20295 UM146_19545 UM146_RS20295 4074166 4074408 - hypothetical protein gene gene4041 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20295 UM146_RS20300 UM146_19550 UM146_RS20300 4074410 4077196 + DNA polymerase I gene gene4042 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20300 UM146_RS20305 UM146_19555 UM146_RS20305 4077578 4078210 - GTP-binding protein gene gene4043 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20305 UM146_RS20310 UM146_19560 UM146_RS20310 4078792 4079301 + der GTPase-activating protein YihI gene gene4044 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20310 UM146_RS20315 UM146_19570 UM146_RS20315 4079490 4080863 + coproporphyrinogen III oxidase catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III gene gene4045 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20315 UM146_RS20320 UM146_19575 UM146_RS20320 4081001 4081111 - hypothetical protein gene gene4046 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20320 UM146_RS20325 UM146_19580 glnG glnG 4081223 4082632 - nitrogen regulation protein NR(I) response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes%3B interacts with sigma-54 gene gene4047 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20325 UM146_RS20330 UM146_19585 glnL glnL 4082644 4083693 - PAS domain-containing two-component system sensor histidine kinase sensory histidine kinase in two-component regulatory system with GlnG%3B acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation gene gene4048 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20330 UM146_RS20335 UM146_19590 glnA glnA 4083867 4085276 - glutamine synthetase forms a homododecamer%3B forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate%3B also functions in the assimilation of ammonia%3B highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues%3B addition of adenylyl groups results in inactivation of the enzyme gene gene4049 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20335 UM146_RS20340 UM146_RS20340 UM146_RS20340 4085255 4085488 - hypothetical protein gene gene4050 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20340 UM146_RS20345 UM146_19595 UM146_RS20345 4085649 4087472 + GTP-binding protein gene gene4051 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20345 UM146_RS20350 UM146_19600 UM146_RS20350 4087579 4088367 - DeoR family transcriptional regulator gene gene4052 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20350 UM146_RS20355 UM146_19605 UM146_RS20355 4088407 4089303 - sugar kinase gene gene4053 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20355 UM146_RS20360 UM146_19610 UM146_RS20360 4089475 4090353 + NADH-dependent gamma-hydroxybutyrate dehydrogenase gene gene4054 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20360 UM146_RS20365 UM146_19615 UM146_RS20365 4090378 4091265 + aldolase gene gene4055 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20365 UM146_RS20370 UM146_19620 UM146_RS20370 4091298 4092308 + molecular chaperone GroES gene gene4056 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20370 UM146_RS20375 UM146_19625 UM146_RS20375 4092378 4093811 + MFS transporter gene gene4057 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20375 UM146_RS20380 UM146_19630 UM146_RS20380 4093910 4095259 + MFS transporter gene gene4058 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20380 UM146_RS20385 UM146_19635 UM146_RS20385 4095249 4096136 + aldose epimerase gene gene4059 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20385 UM146_RS20390 UM146_19640 UM146_RS20390 4096277 4096876 + phosphatase gene gene4060 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20390 UM146_RS20395 UM146_19645 UM146_RS20395 4096870 4097742 + membrane protein gene gene4061 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20395 UM146_RS20400 UM146_19650 UM146_RS20400 4097739 4098176 + D-aminoacyl-tRNA deacylase hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr)%3B possible defense mechanism against a harmful effect of D-tyrosine gene gene4062 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20400 UM146_RS20405 UM146_19655 UM146_RS20405 4098221 4099162 + hypothetical protein gene gene4063 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20405 UM146_RS20410 UM146_19660 UM146_RS20410 4099226 4100134 - lipase gene gene4064 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20410 UM146_RS20415 UM146_19665 UM146_RS20415 4100363 4100674 + hypothetical protein gene gene4065 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20415 UM146_RS20420 UM146_19670 UM146_RS20420 4100675 4100965 + Cro/Cl family transcriptional regulator gene gene4066 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20420 UM146_RS20425 UM146_19675 UM146_RS20425 4101050 4101262 + hypothetical protein gene gene4067 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20425 UM146_RS20430 UM146_RS20430 UM146_RS20430 4101324 4101602 + hypothetical protein gene gene4068 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20430 UM146_RS20435 UM146_19680 UM146_RS20435 4101997 4102215 + hypothetical protein gene gene4069 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20435 UM146_RS20440 UM146_19685 UM146_RS20440 4102431 4103360 - protein FdhE required for the formation of active formate dehydrogenase gene gene4070 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20440 UM146_RS20445 UM146_19690 UM146_RS20445 4103357 4103992 - formate dehydrogenase cytochrome b556(fdo) subunit cytochrome b556(FDO) component%3B heme containing gene gene4071 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20445 UM146_RS20450 UM146_19695 UM146_RS20450 4103989 4104891 - formate dehydrogenase-O iron-sulfur subunit beta subunit%3B involved in the use of formate as an electron donor during aerobic respiration%3B acts to transfer electrons from the major(alpha subunit) to the cytochrome b556(gamma subunit) gene gene4072 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20450 UM146_RS20455 UM146_19700 UM146_RS20455 4104904 4107318 - formate dehydrogenase subunit alpha gene gene4073 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20455 UM146_RS20460 UM146_19705 UM146_RS20460 4107367 4107954 - sulfate ABC transporter substrate-binding protein gene gene4074 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20460 UM146_RS20465 UM146_19710 UM146_RS20465 4108148 4108981 + protein FdhD involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth gene gene4075 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20465 UM146_RS20470 UM146_RS20470 UM146_RS20470 4109069 4109263 + hypothetical protein gene gene4076 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20470 UM146_RS20475 UM146_RS20475 UM146_RS20475 4109377 4109757 + hypothetical protein gene gene4077 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20475 UM146_RS20480 UM146_19725 UM146_RS20480 4110111 4111505 + glycoporin gene gene4078 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20480 UM146_RS20485 UM146_19730 UM146_RS20485 4111546 4111860 - L-rhamnose mutarotase gene gene4079 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20485 UM146_RS20490 UM146_19735 UM146_RS20490 4111870 4112694 - rhamnulose-1-phosphate aldolase gene gene4080 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20490 UM146_RS20495 UM146_19740 UM146_RS20495 4112971 4114230 - L-rhamnose isomerase catalyzes the formation of L-rhamnulose from L-rhamnose gene gene4081 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20495 UM146_RS20500 UM146_19745 rhaB rhaB 4114227 4115696 - rhamnulokinase catalyzes the ATP-dependent phosphorylation of rhamnulose gene gene4082 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20500 UM146_RS20505 UM146_19750 UM146_RS20505 4115775 4115924 + hypothetical protein gene gene4083 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20505 UM146_RS20510 UM146_19755 UM146_RS20510 4115984 4116820 + AraC family transcriptional regulator gene gene4084 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20510 UM146_RS20515 UM146_19760 UM146_RS20515 4116894 4117742 + HTH-type transcriptional activator RhaR activates the expression of rhaRS in response to L-rhamnose gene gene4085 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20515 UM146_RS20520 UM146_19765 UM146_RS20520 4117739 4118773 - l-rhamnose-proton symporter transports L-rhamnose and L-lyxose into the cell gene gene4086 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20520 UM146_RS20525 UM146_19770 UM146_RS20525 4119058 4119678 + superoxide dismutase SodA%3B manganese binding%3B only present under aerobic conditions%3B destroys free radicals gene gene4087 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20525 UM146_RS20530 UM146_19775 UM146_RS20530 4119707 4119835 - hypothetical protein gene gene4088 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20530 UM146_RS20535 UM146_19780 UM146_RS20535 4119938 4120921 + 2-keto-3-deoxygluconate permease transports degraded pectin products into the bacterial cell gene gene4089 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20535 UM146_RS20540 UM146_19785 UM146_RS20540 4121070 4121744 + 6-N-hydroxylaminopurine resistance protein gene gene4090 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20540 UM146_RS20545 UM146_19790 cpxA cpxA 4121850 4123223 - two-component system sensor histidine kinase part of two-component CpxA/CpxR system%3B senses envelope stress%3B upregulates a number of periplasmic folding and trafficking factors gene gene4091 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20545 UM146_RS20550 UM146_19795 UM146_RS20550 4123220 4123918 - two-component system response regulator response regulator in two-component regulatory system with CpxA%3B part of the envelope stress response system gene gene4092 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20550 UM146_RS20555 UM146_19800 cpxP cpxP 4124068 4124568 + repressor CpxP repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA%3B CpxP is degraded by DegP protease especially in the presence of misfolded substrates gene gene4093 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20555 UM146_RS20560 UM146_19805 fieF fieF 4124716 4125618 + iron transporter member of cation diffusion facilitator family%3B CDF%3B membrane-bound%3B induced by both zinc and iron%2C but does not induce resistance to zinc%3B can transport zinc(II) in a proton-dependent manner%3B instead this protein induces iron resistance%3B forms dimers gene gene4094 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20560 UM146_RS20565 UM146_19810 UM146_RS20565 4125799 4126761 + ATP-dependent 6-phosphofructokinase catalyzes the formation of D-fructose 1%2C6-bisphosphate from D-fructose 6-phosphate in glycolysis gene gene4095 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20565 UM146_RS20575 UM146_19815 UM146_RS20575 4127081 4128070 + sulfate transporter subunit gene gene4096 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20575 UM146_RS20580 UM146_19820 UM146_RS20580 4128176 4128931 + CDP-diacylglycerol pyrophosphatase gene gene4097 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20580 UM146_RS20585 UM146_19825 UM146_RS20585 4128986 4129753 - triosephosphate isomerase Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate gene gene4098 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20585 UM146_RS20590 UM146_19830 UM146_RS20590 4129861 4130460 - hypothetical protein gene gene4099 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20590 UM146_RS20595 UM146_19835 UM146_RS20595 4130561 4131001 + membrane protein gene gene4100 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20595 UM146_RS20600 UM146_19840 UM146_RS20600 4131213 4131512 + hypothetical protein gene gene4101 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20600 UM146_RS20605 UM146_19845 UM146_RS20605 4131539 4131967 + universal stress protein D with UspC and Usp E is involved in resistance to UV radiation gene gene4102 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20605 UM146_RS20610 UM146_19850 UM146_RS20610 4131972 4132718 - ferredoxin--NADP reductase gene gene4103 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20610 UM146_RS20615 UM146_19855 UM146_RS20615 4132815 4133825 - fructose 1%2C6-bisphosphatase gene gene4104 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20615 UM146_RS20620 UM146_19860 glpK glpK 4133996 4135486 - glycerol kinase Converts glycerol and ADP to glycerol-3-phosphate and ADP gene gene4105 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20620 UM146_RS20625 UM146_19865 UM146_RS20625 4135526 4136370 - glycerol uptake facilitator GlpF involved in the transport of glycerol into the cell gene gene4106 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20625 UM146_RS20630 UM146_RS20630 UM146_RS20630 4136801 4137039 + septal ring assembly protein ZapB interacts with FisZ and is necessary for Z-ring formation gene gene4107 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20630 UM146_RS20635 UM146_19880 UM146_RS20635 4137124 4137609 - regulator of ribonuclease activity A regulator of RNase E%3B increases half-life and abundance of RNAs%3B interacts with RNase E possibly inhibiting catalytic activity gene gene4108 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20635 UM146_RS20640 UM146_19885 UM146_RS20640 4137702 4138628 - 1%2C4-dihydroxy-2-naphthoate octaprenyltransferase catalyzes the formation of dimethylmenaquinone from 1%2C4-dihydroxy-2-naphthoate and octaprenyl diphosphate gene gene4109 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20640 UM146_RS20645 UM146_19890 hslU hslU 4138695 4140026 - ATP-dependent protease ATPase subunit HslU heat shock protein involved in degradation of misfolded proteins gene gene4110 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20645 UM146_RS20650 UM146_19895 UM146_RS20650 4140036 4140566 - ATP-dependent protease subunit HslV gene gene4111 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20650 UM146_RS20655 UM146_19900 UM146_RS20655 4140659 4141513 - cell division protein FtsN gene gene4112 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20655 UM146_RS20660 UM146_RS20660 UM146_RS20660 4141710 4142734 - transcriptional regulator negatively controls the transcription initiation of genes such as deoCABD%2C udp%2C and cdd encoding catabolizing enzymes and nupC%2C nupG%2C and tsx encoding transporting and pore-forming proteins gene gene4113 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20660 UM146_RS20665 UM146_19915 UM146_RS20665 4142890 4145088 - primosome assembly protein PriA binding of PriA to forked DNA starts the assembly of the primosome%2C also possesses 3'-5' helicase activity gene gene4114 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20665 UM146_RS20670 UM146_19920 rpmE rpmE 4145291 4145503 + 50S ribosomal protein L31 RpmE%3B there appears to be two types of ribosomal proteins L31 in bacterial genomes%3B some contain a CxxC motif while others do not%3B Bacillus subtilis has both types%3B the proteins in this cluster have the CXXC motif%3B RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth%3B expression of ytiA is controlled by a zinc-specific transcriptional repressor%3B RpmE contains one zinc ion and a CxxC motif is responsible for this binding%3B forms an RNP particle along with proteins L5%2C L18%2C and L25 and 5S rRNA%3B found crosslinked to L2 and L25 and EF-G%3B may be near the peptidyltransferase site of the 50S ribosome gene gene4115 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20670 UM146_RS20675 UM146_19925 UM146_RS20675 4145564 4146172 - hypothetical protein gene gene4116 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20675 UM146_RS20680 UM146_RS20680 UM146_RS20680 4146232 4146548 - transcriptional repressor protein MetJ when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis gene gene4117 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20680 UM146_RS20685 UM146_19935 UM146_RS20685 4146825 4147985 + cystathionine gamma-synthase catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine gene gene4118 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20685 UM146_RS20690 UM146_19940 metL metL 4147988 4150420 + bifunctional aspartate kinase II/homoserine dehydrogenase II multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine%3B functions in a number of amino acid biosynthetic pathways gene gene4119 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20690 UM146_RS20695 UM146_19945 UM146_RS20695 4150638 4151498 - ion channel protein Tsx gene gene4120 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20695 UM146_RS20700 UM146_19950 UM146_RS20700 4151575 4153194 - 5'-nucleotidase gene gene4121 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20700 UM146_RS20705 UM146_19955 UM146_RS20705 4153235 4154785 - 5'-nucleotidase gene gene4122 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20705 UM146_RS20710 UM146_RS20710 UM146_RS20710 4155018 4156142 - hypothetical protein gene gene4123 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20710 UM146_RS20715 UM146_19960 UM146_RS20715 4156275 4157828 + 5'-nucleotidase gene gene4124 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20715 UM146_RS20720 UM146_19965 metF metF 4158210 4159100 + 5%2C10-methylenetetrahydrofolate reductase MTHFR%3B catalyzes NADH-linked reduction of 5%2C10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor gene gene4125 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20720 UM146_RS20725 UM146_19970 UM146_RS20725 4159429 4161609 + catalase-peroxidase gene gene4126 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20725 UM146_RS20730 UM146_19975 UM146_RS20730 4161703 4162608 + permease gene gene4127 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20730 UM146_RS20735 UM146_19980 UM146_RS20735 4162635 4163252 - hypothetical protein gene gene4128 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20735 UM146_RS20740 UM146_RS20740 UM146_RS20740 4163364 4163483 - hypothetical protein gene gene4129 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20740 UM146_RS20745 UM146_19985 gldA gldA 4163527 4164630 - glycerol dehydrogenase forms dimers and octamers%3B involved in conversion of glycerol to dihydroxy-acetone gene gene4130 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20745 UM146_RS20750 UM146_19990 UM146_RS20750 4164641 4165303 - fructose-6-phosphate aldolase similar to transaldolase from Escherichia coli%3B many organisms have multiple copies gene gene4131 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20750 UM146_RS20755 UM146_19995 UM146_RS20755 4165315 4167816 - PTS fructose transporter subunit IIA Phosphotransferase system%2C enzyme I%3B transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein HPr%3B HPr transfers the phosphoryl group to subunit A%3B subunit IIA transfers a phosphoryl group to subunit IIB%3B subunit IIB transfers the phosphoryl group to the substrate%3B part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active-transport system gene gene4132 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20755 UM146_RS20760 UM146_20000 UM146_RS20760 4168125 4169204 + PTS fructose transporter subunit IIC gene gene4133 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20760 UM146_RS20765 UM146_20005 UM146_RS20765 4169219 4169539 + fructose-like phosphotransferase enzyme IIB component 2 FrwB with FrwC%2C FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell%3B cytoplasmic protein that interacts with complex EIIA%3B contains the second phosphorylation site of the PTS gene gene4134 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20765 UM146_RS20770 UM146_20010 pflD pflD 4169590 4171887 + formate acetyltransferase involved in production of D-lactate from glucose under microaerobic conditions%3B cytoplasmic protein gene gene4135 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20770 UM146_RS20775 UM146_20015 UM146_RS20775 4171853 4172731 + pyruvate formate lyase II activase gene gene4136 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20775 UM146_RS20780 UM146_20020 UM146_RS20780 4172733 4173074 + PTS fructose transporter subunit IIB FrwD with FrwB%2C FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell%3B phosphorylated by EIIA%3B FrwB homolog gene gene4137 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20780 UM146_RS20785 UM146_20025 UM146_RS20785 4173061 4173912 - AraC family transcriptional regulator gene gene4138 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20785 UM146_RS20790 UM146_20030 UM146_RS20790 4174138 4175871 - phosphoethanolamine transferase EptC gene gene4139 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20790 UM146_RS20795 UM146_20035 UM146_RS20795 4176054 4178705 - phosphoenolpyruvate carboxylase catalyzes the formation of oxaloacetate from phosphoenolpyruvate gene gene4140 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20795 UM146_RS20800 UM146_20040 UM146_RS20800 4179007 4180158 - acetylornithine deacetylase catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis gene gene4141 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20800 UM146_RS20805 UM146_20045 UM146_RS20805 4180312 4181316 + N-acetyl-gamma-glutamyl-phosphate reductase gene gene4142 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20805 UM146_RS20810 UM146_20050 UM146_RS20810 4181327 4182100 + acetylglutamate kinase gene gene4143 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20810 UM146_RS20815 UM146_20055 UM146_RS20815 4182161 4183534 + argininosuccinate lyase catalyzes the formation of arginine from (N-L-arginino)succinate gene gene4144 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20815 UM146_RS20820 UM146_20060 UM146_RS20820 4184032 4185246 + bifunctional D-altronate/D-mannonate dehydratase starvation-sensing protein%3B maybe involved in homoserine lactone degradation gene gene4145 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20820 UM146_RS20825 UM146_20065 UM146_RS20825 4185313 4186596 + MFS transporter gene gene4146 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20825 UM146_RS20830 UM146_20070 UM146_RS20830 4186848 4187765 + hydrogen peroxide-inducible genes activator Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG%2C gor%2C ahpC%2C ahpF%2C oxyS%2C dps%2C fur and grxA gene gene4147 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20830 UM146_RS20835 UM146_20075 UM146_RS20835 4187748 4189148 - soluble pyridine nucleotide transhydrogenase catalyzes the conversion of NADPH to NADH gene gene4148 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20835 UM146_RS20840 UM146_20080 UM146_RS20840 4189478 4190644 + peptidase M20 gene gene4149 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20840 UM146_RS20845 UM146_20085 UM146_RS20845 4190687 4192003 + MFS transporter gene gene4150 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20845 UM146_RS20850 UM146_20090 UM146_RS20850 4192110 4192757 + transcriptional regulator negatively controls the expression of fabA and fabB%2C genes involved in the unsaturated fatty acid biosynthesis gene gene4151 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20850 UM146_RS20855 UM146_20095 UM146_RS20855 4192757 4193116 + hypothetical protein gene gene4152 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20855 UM146_RS20860 UM146_20100 UM146_RS20860 4193156 4194256 - tRNA/tmRNA (uracil-C(5))-methyltransferase catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs gene gene4153 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20860 UM146_RS20865 UM146_20105 btuB btuB 4194625 4196469 + vitamin B12 transporter BtuB involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space gene gene4154 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20865 UM146_RS20870 UM146_20110 UM146_RS20870 4196483 4197271 + glutamate racemase converts L-glutamate to D-glutamate%2C a component of peptidoglycan gene gene4155 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20870 UM146_RS20875 UM146_r24015 UM146_RS20875 4197643 4199198 + 16S ribosomal RNA rRNA gene4157 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20875 UM146_RS20880 UM146_t23967 UM146_RS20880 4199272 4199347 + tRNA-Glu tRNA gene4158 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20880 UM146_RS20885 UM146_r24029 UM146_RS20885 4199532 4202456 + 23S ribosomal RNA rRNA gene4159 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20885 UM146_RS20890 UM146_r24003 UM146_RS20890 4202545 4202660 + 5S ribosomal RNA rRNA gene4160 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20890 UM146_RS20895 UM146_20115 UM146_RS20895 4202737 4203120 + hypothetical protein gene gene4161 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20895 UM146_RS20900 UM146_20120 UM146_RS20900 4203184 4203627 - acetyltransferase gene gene4162 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20900 UM146_RS20905 UM146_20125 UM146_RS20905 4203784 4204713 + homoserine O-succinyltransferase catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis gene gene4163 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20905 UM146_RS20910 UM146_20130 UM146_RS20910 4204982 4206583 + malate synthase Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle gene gene4164 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20910 UM146_RS20915 UM146_20135 UM146_RS20915 4206613 4207917 + isocitrate lyase gene gene4165 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20915 UM146_RS20920 UM146_20140 aceK aceK 4207966 4209690 + isocitrate dehydrogenase catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity%3B unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol gene gene4166 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20920 UM146_RS20925 UM146_20150 UM146_RS20925 4209707 4210531 - acetate operon repressor regulates the glyoxylate bypass operon (aceBAK)%2C which encodes isocitrate lyase%2C malate synthase and isocitrate dehydrogenase kinase/phosphorylase gene gene4167 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20925 UM146_RS20930 UM146_20155 metH metH 4210731 4214414 + B12-dependent methionine synthase one of two methionine synthases in Escherichia coli%3B MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine%3B requires zinc for activity gene gene4168 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20930 UM146_RS20935 UM146_20170 UM146_RS20935 4214836 4215285 + membrane protein gene gene4169 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20935 UM146_RS20940 UM146_20175 UM146_RS20940 4215456 4217087 + membrane protein gene gene4170 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20940 UM146_RS20945 UM146_20180 UM146_RS20945 4217177 4217866 - peptidase E peptidase E%3B catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue%3B belongs to peptidase S51 family gene gene4171 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20945 UM146_RS20950 UM146_20185 UM146_RS20950 4217973 4218128 + hypothetical protein gene gene4172 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20950 UM146_RS20955 UM146_20190 UM146_RS20955 4218248 4219477 - oxidoreductase gene gene4173 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20955 UM146_RS20960 UM146_20195 UM146_RS20960 4219585 4220352 - PTS mannose transporter subunit IID gene gene4174 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20960 UM146_RS20965 UM146_20200 UM146_RS20965 4220363 4221160 - PTS mannose transporter subunit IIC catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site gene gene4175 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20965 UM146_RS20970 UM146_20205 UM146_RS20970 4221226 4221720 - PTS fructose transporter subunit IIB gene gene4176 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20970 UM146_RS20975 UM146_20210 UM146_RS20975 4221720 4222127 - PTS sorbose transporter subunit IIA gene gene4177 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20975 UM146_RS20980 UM146_20215 UM146_RS20980 4222137 4222943 - sorbitol-6-phosphate 2-dehydrogenase Converts D-sorbitol-dphosphate to D-fructose-6-phosphate gene gene4178 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20980 UM146_RS20985 UM146_20220 UM146_RS20985 4223013 4223960 - Cro/Cl family transcriptional regulator gene gene4179 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20985 UM146_RS20990 UM146_20225 UM146_RS20990 4224308 4225180 + ribosomal large subunit pseudouridine synthase F catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA gene gene4180 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20990 UM146_RS20995 UM146_20230 UM146_RS20995 4225181 4225453 - hypothetical protein gene gene4181 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS20995 UM146_RS21000 UM146_20235 UM146_RS21000 4225706 4227055 - aspartate kinase catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP%3B functions in amino acid biosynthesis%3B lysine sensitive gene gene4182 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21000 UM146_RS21005 UM146_20240 pgi pgi 4227580 4229229 + glucose-6-phosphate isomerase functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis%3B catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate%3B member of PGI family gene gene4183 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21005 UM146_RS21010 UM146_20245 UM146_RS21010 4229727 4229969 + polysaccharide production threonine-rich protein gene gene4184 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21010 UM146_RS21015 UM146_20250 UM146_RS21015 4230084 4230722 + hypothetical protein gene gene4185 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21015 UM146_RS21020 UM146_20255 UM146_RS21020 4230719 4231456 + hypothetical protein gene gene4186 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21020 UM146_RS21025 UM146_20260 UM146_RS21025 4231456 4233552 + membrane protein gene gene4187 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21025 UM146_RS21030 UM146_RS21030 UM146_RS21030 4233599 4233877 - hypothetical protein gene gene4188 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21030 UM146_RS21035 UM146_20265 UM146_RS21035 4233937 4234095 + hypothetical protein gene gene4189 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21035 UM146_RS21040 UM146_20270 UM146_RS21040 4234092 4234502 + protein PsiE gene gene4190 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21040 UM146_RS21045 UM146_20275 malG malG 4234596 4235486 - maltose ABC transporter permease with MalKFE is involved in the transport of maltose into the cell gene gene4191 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21045 UM146_RS21050 UM146_20280 malF malF 4235501 4237045 - maltose transporter membrane protein with MalKGE is involved in maltose transport into the cell gene gene4192 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21050 UM146_RS21055 UM146_20285 malE malE 4237199 4238389 - sugar ABC transporter substrate-binding protein functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis gene gene4193 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21055 UM146_RS21060 UM146_20290 UM146_RS21060 4238482 4238577 - sugar ABC transporter gene gene4194 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21060 UM146_RS21065 UM146_20295 UM146_RS21065 4238754 4239869 + maltose/maltodextrin import ATP-binding protein MalK with malEFG is involved in import of maltose/maltodextrin gene gene4195 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21065 UM146_RS21070 UM146_20300 lamB lamB 4239941 4241281 + maltoporin porin involved in the transport of maltose and maltodextrins gene gene4196 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21070 UM146_RS21075 UM146_20305 UM146_RS21075 4241604 4242524 + maltose operon protein gene gene4197 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21075 UM146_RS21080 UM146_20310 ubiC ubiC 4242703 4243200 + Chorismate pyruvate-lyase catalyzes the formation of 4-hydroxybenzoate from chorismate gene gene4198 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21080 UM146_RS21085 UM146_20315 ubiA ubiA 4243213 4244085 + 4-hydroxybenzoate octaprenyltransferase catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate%2C as part of the ubiquinone biosynthesis pathway gene gene4199 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21085 UM146_RS21090 UM146_20320 UM146_RS21090 4244238 4246661 - glycerol-3-phosphate acyltransferase PlsB%3B catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA gene gene4200 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21090 UM146_RS21095 UM146_20325 UM146_RS21095 4246832 4247200 + diacylglycerol kinase catalyzes the phosphorylation of diacylglycerol to form diacylglycerol phosphate gene gene4201 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21095 UM146_RS21100 UM146_20330 UM146_RS21100 4247310 4247918 + LexA repressor Represses a number of genes involved in the response to DNA damage gene gene4202 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21100 UM146_RS21105 UM146_20335 UM146_RS21105 4247991 4249316 + MATE family efflux transporter gene gene4203 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21105 UM146_RS21110 UM146_20340 UM146_RS21110 4249432 4249641 + hypothetical protein gene gene4204 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21110 UM146_RS21115 UM146_20345 UM146_RS21115 4249683 4250198 - transcriptional regulator Acts as a negative controlling element%2C employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB gene gene4205 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21115 UM146_RS21120 UM146_20350 UM146_RS21120 4250354 4251349 + tRNA-dihydrouridine synthase A gene gene4206 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21120 UM146_RS21125 UM146_20355 pspG pspG 4251483 4251725 + phage-shock protein coordinately regulated along with pspA%3B PspF-dependent induction in response to secretin overexpression in Yersinia gene gene4207 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21125 UM146_RS21130 UM146_20360 UM146_RS21130 4251890 4252873 - quinone oxidoreductase gene gene4208 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21130 UM146_RS21135 UM146_20365 UM146_RS21135 4252979 4255027 - oxidoreductase gene gene4209 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21135 UM146_RS21140 UM146_20370 UM146_RS21140 4255017 4256417 - MFS transporter gene gene4210 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21140 UM146_RS21145 UM146_20375 UM146_RS21145 4256508 4257287 - enoyl-CoA hydratase gene gene4211 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21145 UM146_RS21150 UM146_20380 UM146_RS21150 4257280 4258851 - CoA-transferase gene gene4212 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21150 UM146_RS21155 UM146_20385 UM146_RS21155 4259107 4260141 + regulator gene gene4213 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21155 UM146_RS21160 UM146_20390 UM146_RS21160 4260214 4261629 + replicative DNA helicase unwinds double stranded DNA gene gene4214 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21160 UM146_RS21165 UM146_20395 alr alr 4261682 4262761 + alanine racemase biosynthetic converts L-alanine to D-alanine which is used in cell wall biosynthesis%3B binds one pyridoxal phosphate per monomer%3B forms a homodimer gene gene4215 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21165 UM146_RS21170 UM146_20400 UM146_RS21170 4262784 4263341 + nicotinamide mononucleotide transporter gene gene4216 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21170 UM146_RS21175 UM146_20405 UM146_RS21175 4263338 4264336 + NAD metabolism ATPase/kinase gene gene4217 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21175 UM146_RS21180 UM146_20410 UM146_RS21180 4264418 4265611 + aromatic amino acid aminotransferase catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate gene gene4218 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21180 UM146_RS21185 UM146_20415 sucA sucA 4265793 4268537 + 2-oxoglutarate dehydrogenase E1 SucA%3B E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate%3B SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide gene gene4219 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21185 UM146_RS21190 UM146_20420 UM146_RS21190 4268570 4269724 + dihydrolipoamide succinyltransferase gene gene4220 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21190 UM146_RS21195 UM146_20425 UM146_RS21195 4269736 4271154 + dihydrolipoamide dehydrogenase gene gene4221 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21195 UM146_RS21200 UM146_20430 UM146_RS21200 4271176 4272345 + succinyl-CoA synthetase subunit beta gene gene4222 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21200 UM146_RS21205 UM146_20435 UM146_RS21205 4272358 4273230 + succinyl-CoA synthetase subunit alpha Catalyzes the only substrate-level phosphorylation in the TCA cycle gene gene4223 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21205 UM146_RS21210 UM146_20440 UM146_RS21210 4273442 4274941 + membrane protein gene gene4224 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21210 UM146_RS21215 UM146_20445 UM146_RS21215 4274953 4276026 + lactate dehydrogenase gene gene4225 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21215 UM146_RS21220 UM146_20450 UM146_RS21220 4276015 4277373 - Fis family transcriptional regulator gene gene4226 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21220 UM146_RS21225 UM146_20455 UM146_RS21225 4277366 4279186 - two-component system sensor histidine kinase gene gene4227 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21225 UM146_RS21230 UM146_20460 aphA aphA 4279463 4280176 + class B acid phosphatase Class B%3B non-specific%3B catalyzes the dephosphorylation of organic phosphomonoesters%3B also has phosphotransferase activity gene gene4228 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21230 UM146_RS21235 UM146_20465 UM146_RS21235 4280287 4280703 + thiamin phosphate synthase gene gene4229 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21235 UM146_RS21240 UM146_20470 UM146_RS21240 4280707 4281063 + hypothetical protein gene gene4230 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21240 UM146_RS21245 UM146_20475 UM146_RS21245 4281098 4283920 - UvrABC system protein A gene gene4231 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21245 UM146_RS21250 UM146_20480 UM146_RS21250 4284174 4284710 + single-stranded DNA-binding protein binds to single stranded DNA and PriA helcase facilitate replication restart gene gene4232 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21250 UM146_RS21255 UM146_20485 UM146_RS21255 4284809 4285090 - membrane protein gene gene4233 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21255 UM146_RS21260 UM146_20490 UM146_RS21260 4285519 4287105 + membrane protein gene gene4234 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21260 UM146_RS21265 UM146_20495 UM146_RS21265 4287108 4287431 - regulatory protein SoxS regulates genes involved in response to oxidative stress gene gene4235 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21265 UM146_RS21270 UM146_20500 UM146_RS21270 4287517 4287981 + transcriptional regulator gene gene4236 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21270 UM146_RS21275 UM146_20505 UM146_RS21275 4288528 4289877 + permease gene gene4237 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21275 UM146_RS21280 UM146_20510 UM146_RS21280 4290028 4291677 + sodium:proton antiporter gene gene4238 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21280 UM146_RS21285 UM146_20515 UM146_RS21285 4291713 4292597 - transcriptional regulator gene gene4239 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21285 UM146_RS21290 UM146_20520 UM146_RS21290 4292701 4293111 + murein hydrolase regulator LrgA gene gene4240 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21290 UM146_RS21295 UM146_20525 UM146_RS21295 4293104 4293793 + murein hydrolase effector protein LrgB gene gene4241 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21295 UM146_RS21300 UM146_20530 actP actP 4293832 4295481 - cation/acetate symporter ActP member of the sodium:solute symporter family%3B cotranscribed with the acs gene which encodes acetyl coenzyme A synthase%3B mutations affect acetate uptake gene gene4242 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21300 UM146_RS21305 UM146_20535 UM146_RS21305 4295478 4295792 - membrane protein gene gene4243 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21305 UM146_RS21310 UM146_20540 UM146_RS21310 4296084 4298042 - acetyl-CoA synthetase Acs%3B catalyzes the conversion of acetate and CoA to acetyl-CoA gene gene4244 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21310 UM146_RS21315 UM146_20545 nrfA nrfA 4298434 4299870 + cytochrome c-552 catalyzes the formate-dependent reduction of nitrite to ammonia%3B cytochrome C552 gene gene4245 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21315 UM146_RS21320 UM146_20550 UM146_RS21320 4299915 4300481 + cytochrome C nitrite reductase pentaheme subunit part of nitrite reductase complex%3B NrfB is active at high nitrate conditions%3B NrfA%2C B%2C C%2C and D are essential for the formate-dependent nitrite reduction to ammonia gene gene4246 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21320 UM146_RS21325 UM146_20555 UM146_RS21325 4300478 4301149 + formate-dependent nitrite reductase subunit NrfC 4Fe4S subunit%3B may be involved in the transfer of electrons from quinones to the c-type cytochromes gene gene4247 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21325 UM146_RS21330 UM146_20560 UM146_RS21330 4301146 4302102 + formate-dependent nitrite reductase subunit NrfD membrane protein%2C may be involved in the transfer of electrons from quinones to c-type cytochromes gene gene4248 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21330 UM146_RS21335 UM146_20565 UM146_RS21335 4302233 4303840 + heme lyase subunit NrfE with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552 gene gene4249 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21335 UM146_RS21340 UM146_20570 UM146_RS21340 4303833 4304216 + nitrite reductase subunit F gene gene4250 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21340 UM146_RS21345 UM146_20575 UM146_RS21345 4304213 4304809 + formate-dependent nitrite reductase complex subunit NrfG gene gene4251 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21345 UM146_RS21350 UM146_20580 UM146_RS21350 4305152 4306465 + proton glutamate symport protein gene gene4252 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21350 UM146_RS21355 UM146_20585 UM146_RS21355 4306613 4307302 - hypothetical protein gene gene4253 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21355 UM146_RS21360 UM146_20590 UM146_RS21360 4307413 4308117 - peptide ABC transporter ATP-binding protein gene gene4254 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21360 UM146_RS21365 UM146_20595 UM146_RS21365 4308104 4308940 - peptide ABC transporter ATP-binding protein gene gene4255 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21365 UM146_RS21370 UM146_20600 UM146_RS21370 4308933 4309766 - peptide ABC transporter permease gene gene4256 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21370 UM146_RS21375 UM146_20605 UM146_RS21375 4309766 4310815 - peptide ABC transporter permease gene gene4257 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21375 UM146_RS21380 UM146_20610 UM146_RS21380 4310915 4312483 - ABC transporter substrate-binding protein gene gene4258 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21380 UM146_RS21385 UM146_20615 UM146_RS21385 4312858 4314537 - formate dehydrogenase subunit alpha gene gene4259 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21385 UM146_RS21390 UM146_20620 UM146_RS21390 4314586 4315005 - spermidine/putrescine ABC transporter substrate-binding protein gene gene4260 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21390 UM146_RS21395 UM146_20625 UM146_RS21395 4315203 4316669 - multidrug RND transporter part of a multidrug efflux system involved in resistance to acriflavin%2C puromycin%2C erytjhromycin and tetraphenylarsonium chloride%3B member of the outer membrane factor (OMF) family gene gene4261 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21395 UM146_RS21400 UM146_20630 UM146_RS21400 4316666 4318717 - multidrug transporter possibly part of a tripartite efflux system composed of MdtN%2C MdtO and MdtP which could be involved in resistance to puromycin%2C acriflavine and tetraphenylarsonium chloride gene gene4262 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21400 UM146_RS21405 UM146_20635 UM146_RS21405 4318717 4319748 - multidrug resistance protein MdtN with MdtO and MdtP is involved in resistance to puromycin%2C acriflavine and tetraphenylarsonium chloride gene gene4263 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21405 UM146_RS21410 UM146_20640 UM146_RS21410 4319767 4320042 - hypothetical protein gene gene4264 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21410 UM146_RS21415 UM146_20645 UM146_RS21415 4320250 4322235 - hypothetical protein gene gene4265 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21415 UM146_RS21420 UM146_20650 UM146_RS21420 4322510 4323439 - D-allose kinase gene gene4266 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21420 UM146_RS21425 UM146_20655 UM146_RS21425 4323423 4324118 - allulose-6-phosphate 3-epimerase gene gene4267 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21425 UM146_RS21430 UM146_RS21430 UM146_RS21430 4324129 4324836 - cytochrome C6 gene gene4268 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21430 UM146_RS21435 UM146_RS21435 UM146_RS21435 4324864 4325109 - D-allose transporter permease gene gene4269 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21435 UM146_RS21440 UM146_20670 UM146_RS21440 4325088 4326620 - cytochrome C6 with AlsBC acts to import allose into the cell%3B AlsA contain 2 ATP-binding domains gene gene4270 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21440 UM146_RS21445 UM146_20675 UM146_RS21445 4326747 4327682 - cytochrome C gene gene4271 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21445 UM146_RS21450 UM146_20680 UM146_RS21450 4327741 4328631 - RpiR family transcriptional regulator involved in rpiB and als operon repression gene gene4272 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21450 UM146_RS21455 UM146_20685 UM146_RS21455 4328989 4329438 + ribose 5-phosphate isomerase gene gene4273 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21455 UM146_RS21460 UM146_20690 UM146_RS21460 4329507 4329836 + membrane protein gene gene4274 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21460 UM146_RS21465 UM146_20695 phnP phnP 4329864 4330622 - phosphonate metabolism protein PhnP required for the use of phosphonates and phosphite as phosphorus sources gene gene4275 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21465 UM146_RS21470 UM146_20700 UM146_RS21470 4330624 4331058 - aminoalkylphosphonic acid N-acetyltransferase PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids%3B part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source%3B Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role gene gene4276 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21470 UM146_RS21475 UM146_20705 UM146_RS21475 4331045 4331602 - ribose 1%2C5-bisphosphokinase gene gene4277 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21475 UM146_RS21480 UM146_20710 UM146_RS21480 4331602 4332738 - phosphonate metabolism protein PhnM gene gene4278 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21480 UM146_RS21485 UM146_20715 UM146_RS21485 4332735 4333415 - phosphonate ABC transporter ATP-binding protein gene gene4279 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21485 UM146_RS21490 UM146_20720 phnK phnK 4333526 4334284 - phosphonate C-P lyase gene gene4280 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21490 UM146_RS21495 UM146_20725 UM146_RS21495 4334281 4335126 - carbon-phosphorus lyase complex subunit PhnJ gene gene4281 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21495 UM146_RS21500 UM146_20730 UM146_RS21500 4335119 4336183 - carbon-phosphorus lyase complex subunit PhnI required for the use of phosphonate and phosphite gene gene4282 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21500 UM146_RS21505 UM146_20735 phnH phnH 4336183 4336767 - phosphonate C-P lyase system protein PhnH gene gene4283 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21505 UM146_RS21510 UM146_20740 UM146_RS21510 4336764 4337216 - phosphonate C-P lyase system protein PhnG gene gene4284 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21510 UM146_RS21515 UM146_20745 UM146_RS21515 4337217 4337942 - transcriptional regulator may be involved in phosphonate uptake and biodegradation gene gene4285 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21515 UM146_RS21520 UM146_20750 UM146_RS21520 4337963 4338742 - phosphonate ABC transporter permease gene gene4286 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21520 UM146_RS21525 UM146_20755 UM146_RS21525 4338848 4339864 - phosphonate ABC transporter substrate-binding protein with PhnCE is involved in the transport of phosphonates gene gene4287 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21525 UM146_RS21530 UM146_20760 UM146_RS21530 4339889 4340677 - phosphonates import ATP-binding protein PhnC gene gene4288 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21530 UM146_RS21535 UM146_20770 UM146_RS21535 4340810 4341253 - hypothetical protein gene gene4289 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21535 UM146_RS21540 UM146_20775 UM146_RS21540 4341413 4341748 - protein PhnA gene gene4290 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21540 UM146_RS21545 UM146_20780 UM146_RS21545 4342151 4344379 + hypothetical protein gene gene4291 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21545 UM146_RS21550 UM146_20785 UM146_RS21550 4344376 4345254 + hypothetical protein gene gene4292 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21550 UM146_RS21555 UM146_20790 UM146_RS21555 4345518 4347020 + glycine/betaine ABC transporter gene gene4293 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21555 UM146_RS21560 UM146_RS21560 UM146_RS21560 4347132 4347221 + membrane-bound BasS regulator gene gene4294 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21560 UM146_RS21565 UM146_20795 UM146_RS21565 4347197 4348288 - two-component system sensor histidine kinase gene gene4295 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21565 UM146_RS21570 UM146_20800 UM146_RS21570 4348298 4348966 - two-component system response regulator response regulator in two-component regulatory system with BasS gene gene4296 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21570 UM146_RS21575 UM146_20805 UM146_RS21575 4348963 4350606 - metal dependent hydrolase gene gene4297 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21575 UM146_RS21580 UM146_20810 UM146_RS21580 4350710 4352047 - arginine/agmatine antiporter gene gene4298 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21580 UM146_RS21585 UM146_20815 UM146_RS21585 4352184 4352945 - transcriptional regulator regulates genes involved in arginine decarboxylase gene gene4299 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21585 UM146_RS21590 UM146_20820 UM146_RS21590 4353281 4355551 - arginine decarboxylase biodegradative%3B catalyzes the formation of agmatine from arginine gene gene4300 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21590 UM146_RS21595 UM146_20825 UM146_RS21595 4355747 4356655 - transcriptional regulator gene gene4301 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21595 UM146_RS21600 UM146_20830 UM146_RS21600 4356687 4356848 + hypothetical protein gene gene4302 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21600 UM146_RS21605 UM146_20835 UM146_RS21605 4356938 4358293 + alpha-galactosidase catalyses the hydrolysis of terminal non-reducing alpha-D-galactose residues in alpha-D-galactosides gene gene4303 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21605 UM146_RS21610 UM146_20840 UM146_RS21610 4358290 4358940 - membrane protein gene gene4304 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21610 UM146_RS21615 UM146_20845 UM146_RS21615 4359063 4360709 - fumarate hydratase catalyzes the formation of malate from fumerate gene gene4305 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21615 UM146_RS21620 UM146_20850 UM146_RS21620 4360787 4362127 - anaerobic C4-dicarboxylate transporter DcuB functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate%3B similar to DcuA%3B DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate%2C malate%2C fumarate and succinate) transporters gene gene4306 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21620 UM146_RS21625 UM146_RS21625 UM146_RS21625 4362593 4362721 + glutamate decarboxylase gene gene4307 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21625 UM146_RS21630 UM146_20855 UM146_RS21630 4362698 4363417 - transcriptional regulator response regulator in two-component regulatory system with DcuS%3B phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration gene gene4308 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21630 UM146_RS21635 UM146_20860 UM146_RS21635 4363414 4365045 - sensor histidine kinase C4-dicarboxylate-sensing histidine kinase%3B part of two-component regulatory system with DcuR%3B regulates anaerobic fumarate respiration gene gene4309 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21635 UM146_RS21640 UM146_20865 UM146_RS21640 4365226 4365456 + hypothetical protein gene gene4310 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21640 UM146_RS21645 UM146_20870 UM146_RS21645 4365468 4365740 + hypothetical protein gene gene4311 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21645 UM146_RS21650 UM146_20875 UM146_RS21650 4366058 4366264 + hypothetical protein gene gene4312 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21650 UM146_RS21655 UM146_20880 UM146_RS21655 4366292 4366465 + toxin of GhoTS toxin-antitoxin pair%3B membrane-lytic protein%3B stimulator of persister cell formation gene gene4313 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21655 UM146_RS21660 UM146_20885 lysS lysS 4366584 4368101 - lysine--tRNA ligase heat inducible class II%3B LysRS2%3B catalyzes a two-step reaction%2C first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B in Methanosarcina barkeri%2C LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 gene gene4314 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21660 UM146_RS21665 UM146_20890 UM146_RS21665 4368338 4369795 - peptide permease gene gene4315 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21665 UM146_RS21670 UM146_20895 UM146_RS21670 4369854 4372001 - lysine decarboxylase CadA constitutive%3B catalyzes the formation of cadaverine from lysine gene gene4316 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21670 UM146_RS21675 UM146_20900 cadB cadB 4372081 4373415 - cadaverine/lysine antiporter antiporter protein responsible for lysine import and cadaverine export%3B member of the lysine-dependent acid resistance system 4 (AR4)%3B inner membrane protein gene gene4317 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21675 UM146_RS21680 UM146_20905 UM146_RS21680 4373781 4375319 - transcriptional regulator regulates the cadBA operon gene gene4318 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21680 UM146_RS21685 UM146_RS21685 UM146_RS21685 4375606 4375824 + hypothetical protein gene gene4319 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21685 UM146_RS21690 UM146_t23969 UM146_RS21690 4375936 4376011 - tRNA-Phe tRNA gene4320 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21690 UM146_RS21695 UM146_20915 UM146_RS21695 4376118 4376693 - transcriptional regulator gene gene4321 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21695 UM146_RS21700 UM146_20920 dipZ dipZ 4376730 4378427 - thiol:disulfide interchange protein DsbD two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm%3B DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm gene gene4322 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21700 UM146_RS21705 UM146_20925 UM146_RS21705 4378403 4378741 - divalent-cation tolerance protein CutA copper binding protein required for copper tolerance%3B involved in resistance toward heavy metals gene gene4323 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21705 UM146_RS21710 UM146_20930 UM146_RS21710 4378857 4380158 - anaerobic C4-dicarboxylate transporter DcuA functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate%3B similar to dcuB gene gene4324 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21710 UM146_RS21715 UM146_20935 aspA aspA 4380276 4381712 - aspartate ammonia-lyase catalyzes the formation of fumarate from aspartate gene gene4325 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21715 UM146_RS21720 UM146_20940 fxsA fxsA 4382049 4382525 + exclusion suppressor FxsA F exclusion of bacteriophage T7%3B overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7%3B interacts with the F plasmid-encoded PifA protein%3B inner membrane protein gene gene4326 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21720 UM146_RS21725 UM146_20945 UM146_RS21725 4382541 4383797 - transporter uncharacterized member of the APC superfamily of amino acid transporters%3B unknown function gene gene4327 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21725 UM146_RS21730 UM146_20950 groES groES 4384072 4384365 + molecular chaperone GroES 10 kDa chaperonin%3B Cpn10%3B GroES%3B forms homoheptameric ring%3B binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it%3B folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES%3B release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring gene gene4328 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21730 UM146_RS21735 UM146_20955 groEL groEL 4384409 4386055 + chaperonin GroEL 60 kDa chaperone family%3B promotes refolding of misfolded polypeptides especially under stressful conditions%3B forms two stacked rings of heptamers to form a barrel-shaped 14mer%3B ends can be capped by GroES%3B misfolded proteins enter the barrel where they are refolded when GroES binds%3B many bacteria have multiple copies of the groEL gene which are active under different environmental conditions%3B the B.japonicum protein in this cluster is expressed constitutively%3B in Rhodobacter%2C Corynebacterium and Rhizobium this protein is essential for growth gene gene4329 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21735 UM146_RS21740 UM146_20960 UM146_RS21740 4386193 4386546 + DUF4156 domain-containing protein gene gene4330 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21740 UM146_RS21745 UM146_20965 UM146_RS21745 4386596 4387465 - hypothetical protein gene gene4331 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21745 UM146_RS21750 UM146_20970 UM146_RS21750 4387700 4388728 - EF-P beta-lysylation protein EpmB gene gene4332 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21750 UM146_RS21755 UM146_20975 UM146_RS21755 4388770 4389336 + elongation factor P gene gene4333 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21755 UM146_RS21760 UM146_20980 UM146_RS21760 4389388 4389513 + entericidin A acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex gene gene4334 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21760 UM146_RS21765 UM146_20985 UM146_RS21765 4389624 4389770 + entericidin B gene gene4335 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21765 UM146_RS21770 UM146_20990 UM146_RS21770 4389946 4390263 + quaternary ammonium compound-resistance protein SugE member of the SMR family of proton-dependent drug efflux transporters%3B quaternary ammonium compound efflux pump%3B confers resistance to cetylpyridinium%2C cetyldimethylethyl ammonium and cetrimide cations gene gene4336 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21770 UM146_RS21775 UM146_20995 UM146_RS21775 4390260 4390793 - hypothetical protein lipocalin%3B globomycin-sensitive outer membrane lipoprotein gene gene4337 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21775 UM146_RS21780 UM146_21000 UM146_RS21780 4390882 4392015 - BlaEC family class C beta-lactamase gene gene4338 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21780 UM146_RS21785 UM146_21005 UM146_RS21785 4392078 4392437 - fumarate reductase subunit D in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane gene gene4339 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21785 UM146_RS21790 UM146_21010 UM146_RS21790 4392448 4392843 - fumarate reductase subunit C part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration%3B FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit%2C respectively%3B FrdCD are the membrane components which interact with quinone and are involved in electron transfer%3B the catalytic subunits are similar to succinate dehydrogenase SdhAB gene gene4340 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21790 UM146_RS21795 UM146_21015 UM146_RS21795 4392854 4393588 - fumarate reductase iron-sulfur subunit part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration%3B FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit%2C respectively%3B FrdCD are the membrane components which interact with quinone and are involved in electron transfer%3B the catalytic subunits are similar to succinate dehydrogenase SdhAB gene gene4341 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21795 UM146_RS21800 UM146_21020 UM146_RS21800 4393581 4395389 - fumarate reductase flavoprotein subunit part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration%3B FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit%2C respectively%3B FrdCD are the membrane components which interact with quinone and are involved in electron transfer%3B the catalytic subunits are similar to succinate dehydrogenase SdhAB gene gene4342 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21800 UM146_RS21805 UM146_21025 UM146_RS21805 4395714 4396691 + elongation factor P--(R)-beta-lysine ligase poxA%3B regulates pyruvate oxidase poxB gene gene4343 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21805 UM146_RS21810 UM146_21030 UM146_RS21810 4396910 4398412 + amino acid ABC transporter permease gene gene4344 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21810 UM146_RS21815 UM146_21035 UM146_RS21815 4398475 4398789 + hypothetical protein gene gene4345 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21815 UM146_RS21820 UM146_21040 UM146_RS21820 4398786 4399100 + hypothetical protein gene gene4346 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21820 UM146_RS21825 UM146_21045 UM146_RS21825 4399131 4402454 - mechanosensitive channel protein gene gene4347 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21825 UM146_RS21830 UM146_21050 psd psd 4402476 4403444 - phosphatidylserine decarboxylase proenzyme catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine gene gene4348 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21830 UM146_RS21835 UM146_21055 UM146_RS21835 4403541 4404593 - GTPase RsgA EngC%3B RsgA%3B CpgA%3B circularly permuted GTPase%3B ribosome small subunit-dependent GTPase A%3B has the pattern G4-G1-G3 as opposed to other GTPases%3B interacts strongly with 30S ribosome which stimulates GTPase activity gene gene4349 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21835 UM146_RS21840 UM146_21060 UM146_RS21840 4404688 4405233 + oligoribonuclease 3'-5' exoribonuclease specific for small oligoribonuclotides gene gene4350 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21840 UM146_RS21845 UM146_t23971 UM146_RS21845 4405444 4405519 + tRNA-Gly tRNA gene4351 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21845 UM146_RS21850 UM146_t23973 UM146_RS21850 4405556 4405632 + tRNA-Gly tRNA gene4352 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21850 UM146_RS21855 UM146_t23975 UM146_RS21855 4405668 4405743 + tRNA-Gly tRNA gene4353 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21855 UM146_RS21860 UM146_21065 UM146_RS21860 4406013 4407152 - epoxyqueuosine reductase gene gene4354 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21860 UM146_RS21865 UM146_21070 UM146_RS21865 4407166 4408698 + carbohydrate kinase gene gene4355 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21865 UM146_RS21870 UM146_21075 UM146_RS21870 4408670 4409131 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaE needed for nucleoid integrity%3B possibly involved in cell wall synthesis gene gene4356 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21870 UM146_RS21875 UM146_21080 UM146_RS21875 4409150 4410487 + N-acetylmuramoyl-L-alanine amidase gene gene4357 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21875 UM146_RS21880 UM146_21085 UM146_RS21880 4410497 4412344 + DNA mismatch repair protein MutL gene gene4358 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21880 UM146_RS21885 UM146_21090 miaA miaA 4412337 4413287 + tRNA dimethylallyltransferase IPP transferase%3B isopentenyltransferase%3B involved in tRNA modification%3B in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil%3B further tRNA modifications may occur%3B mutations in miaA result in defects in translation efficiency and fidelity gene gene4359 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21885 UM146_RS21890 UM146_21095 hfq hfq 4413373 4413681 + RNA chaperone Hfq HF-I%2C host factor for RNA phage Q beta replication gene gene4360 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21890 UM146_RS21895 UM146_21100 UM146_RS21895 4413757 4415037 + GTPase HflX involved in modulation of proteins HflK and HflC%3B part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein gene gene4361 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21895 UM146_RS21900 UM146_21105 UM146_RS21900 4415123 4416382 + cell division protein FtsH with HflC inhibits proteolysis of lambda cII protein by FtsH gene gene4362 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21900 UM146_RS21905 UM146_21110 UM146_RS21905 4416385 4417389 + modulator of FtsH protease HflC with HflK inhibits proteolysis of lambda cII protein by FtsH gene gene4363 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21905 UM146_RS21910 UM146_21115 UM146_RS21910 4417471 4417668 + membrane protein gene gene4364 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21910 UM146_RS21915 UM146_21125 UM146_RS21915 4417772 4419069 + adenylosuccinate synthetase catalyzes the formation of N6-(1%2C2%2C-dicarboxyethyl)-AMP from L-aspartate%2C inosine monophosphate and GTP in AMP biosynthesis gene gene4365 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21915 UM146_RS21920 UM146_21130 UM146_RS21920 4419274 4419699 + transcriptional regulator negatively regulates the transcription of genes upregulated by nitrosative stress gene gene4366 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21920 UM146_RS21925 UM146_21135 UM146_RS21925 4419738 4422179 + exoribonuclease R 3'-5'exoribonuclease that acts nonspecifically on poly(A)%2C poly(U) and ribosomal RNAs gene gene4367 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21925 UM146_RS21930 UM146_21140 UM146_RS21930 4422271 4423002 + 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB Specifically methylates the ribose of guanosine 2251 in 23S rRNA gene gene4368 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21930 UM146_RS21935 UM146_21145 UM146_RS21935 4423128 4423529 + hypothetical protein gene gene4369 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21935 UM146_RS21940 UM146_21150 UM146_RS21940 4423548 4424246 + PspA/IM30 family protein gene gene4370 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21940 UM146_RS21945 UM146_21155 UM146_RS21945 4424296 4424955 + hypothetical protein gene gene4371 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21945 UM146_RS21950 UM146_21160 UM146_RS21950 4424973 4425371 + membrane protein gene gene4372 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21950 UM146_RS21955 UM146_21165 UM146_RS21955 4425381 4426019 + membrane protein gene gene4373 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21955 UM146_RS21960 UM146_21170 UM146_RS21960 4426022 4427185 + hypothetical protein gene gene4374 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21960 UM146_RS21965 UM146_21175 UM146_RS21965 4427269 4428894 + isovaleryl CoA dehydrogenase catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA gene gene4375 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21965 UM146_RS21970 UM146_21180 UM146_RS21970 4429011 4429286 - DUF1471 domain-containing protein gene gene4376 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21970 UM146_RS21975 UM146_21185 UM146_RS21975 4429435 4429764 - lipoprotein BsmA in Escherichia coli%2C mutation of this gene affects biofilm maturation%2C stress response%2C and motility gene gene4377 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21975 UM146_RS21980 UM146_21190 UM146_RS21980 4429946 4430695 + esterase YjfP%3B esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro%3B unknown function and substrate in vivo gene gene4378 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21980 UM146_RS21985 UM146_21195 UM146_RS21985 4430692 4431447 - transcriptional regulator negative regulator of ulaG and ulaABCDEF gene gene4379 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21985 UM146_RS21990 UM146_21200 UM146_RS21990 4431555 4432619 - L-ascorbate-6-phosphate lactonase UlaG gene gene4380 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21990 UM146_RS21995 UM146_21205 UM146_RS21995 4432974 4434371 + ascorbate-specific permease IIC component UlaA gene gene4381 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS21995 UM146_RS22000 UM146_21210 UM146_RS22000 4434387 4434692 + ascorbate-specific phosphotransferase enzyme IIB component involved in the phosphorylation and transport of sugars across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene4382 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22000 UM146_RS22005 UM146_21215 UM146_RS22005 4434702 4435166 + ascorbate-specific phosphotransferase enzyme IIA component involved in the phosphorylation and transport of sugars across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene4383 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22005 UM146_RS22010 UM146_21220 ulaD ulaD 4435180 4435830 + 3-keto-L-gulonate-6-phosphate decarboxylase ulaD catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization gene gene4384 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22010 UM146_RS22015 UM146_21225 UM146_RS22015 4435840 4436694 + L-ribulose-5-phosphate 3-epimerase UlaE gene gene4385 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22015 UM146_RS22020 UM146_21230 araD araD 4436694 4437380 + L-ribulose-5-phosphate 4-epimerase UlaF catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate%3B links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source gene gene4386 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22020 UM146_RS22025 UM146_21235 UM146_RS22025 4437509 4437784 - hypothetical protein gene gene4387 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22025 UM146_RS22030 UM146_RS22030 UM146_RS22030 4437869 4437988 + hypothetical protein gene gene4388 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22030 UM146_RS22035 UM146_21240 rpsF rpsF 4438112 4438507 + 30S ribosomal protein S6 binds cooperatively with S18 to the S15-16S complex%2C allowing platform assembly to continue with S11 and S21 gene gene4389 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22035 UM146_RS22040 UM146_21245 UM146_RS22040 4438514 4438828 + primosomal replication protein n binds single-stranded DNA at the primosome assembly site gene gene4390 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22040 UM146_RS22045 UM146_21250 rpsR rpsR 4438833 4439060 + 30S ribosomal protein S18 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA%3B helps stabilize the platform of the 30S subunit gene gene4391 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22045 UM146_RS22050 UM146_21255 rplI rplI 4439102 4439551 + 50S ribosomal protein L9 in Escherichia coli this protein is wrapped around the base of the L1 stalk gene gene4392 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22050 UM146_RS22055 UM146_RS22055 UM146_RS22055 4439953 4440444 + XRE family transcriptional regulator gene gene4393 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22055 UM146_RS22060 UM146_21265 UM146_RS22060 4440447 4441715 + toxin HipA gene gene4394 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22060 UM146_RS22065 UM146_21270 UM146_RS22065 4441858 4443099 - hexuronate transporter gene gene4395 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22065 UM146_RS22070 UM146_21275 UM146_RS22070 4443109 4443612 - transposase gene gene4396 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22070 UM146_RS22075 UM146_21285 UM146_RS22075 4444005 4446077 - oxidoreductase gene gene4397 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22075 UM146_RS22080 UM146_21290 UM146_RS22080 4446074 4447615 - CoA synthetase gene gene4398 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22080 UM146_RS22085 UM146_21295 UM146_RS22085 4447625 4448401 - acyl-CoA hydratase gene gene4399 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22085 UM146_RS22090 UM146_21300 UM146_RS22090 4448404 4449252 - endonuclease gene gene4400 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22090 UM146_RS22095 UM146_21305 UM146_RS22095 4449262 4450053 - 3-ketoacyl-ACP reductase catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis gene gene4401 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22095 UM146_RS22100 UM146_21310 UM146_RS22100 4450265 4450912 + TetR family transcriptional regulator gene gene4402 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22100 UM146_RS22105 UM146_21315 UM146_RS22105 4450896 4451534 - hypothetical protein gene gene4403 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22105 UM146_RS22110 UM146_21320 UM146_RS22110 4451752 4452372 + FKBP-type peptidyl-prolyl cis-trans isomerase FKBP-type%3B rotamase%3B catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides gene gene4404 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22110 UM146_RS22115 UM146_21325 UM146_RS22115 4452681 4454093 + alanine glycine permease gene gene4405 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22115 UM146_RS22120 UM146_21330 UM146_RS22120 4454138 4454800 - iron-sulfur cluster repair protein YtfE Involved in anaerobic NO protection and iron metabolism gene gene4406 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22120 UM146_RS22125 UM146_21335 UM146_RS22125 4454908 4455873 - membrane protein gene gene4407 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22125 UM146_RS22130 UM146_21340 UM146_RS22130 4455981 4456841 - quinone oxidoreductase gene gene4408 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22130 UM146_RS22135 UM146_21345 UM146_RS22135 4456840 4457310 + HxlR family transcriptional regulator gene gene4409 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22135 UM146_RS22140 UM146_21350 cpdB cpdB 4457439 4459382 - 2'%2C3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic enzyme%3B functions during ribonucleic acid degradation%3B 2'%2C3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate gene gene4410 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22140 UM146_RS22145 UM146_21355 UM146_RS22145 4459572 4460312 + 3'(2')%2C5'-bisphosphate nucleotidase CysQ catalyzes the formation of AMP from adenosine-3'%2C5'-bisphosphate gene gene4411 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22145 UM146_RS22150 UM146_21360 UM146_RS22150 4460302 4460859 - transcriptional regulator gene gene4412 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22150 UM146_RS22155 UM146_21365 UM146_RS22155 4461184 4461390 + DUF1107 domain-containing protein gene gene4413 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22155 UM146_RS22160 UM146_21370 UM146_RS22160 4461468 4462811 - hypothetical protein gene gene4414 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22160 UM146_RS22165 UM146_21375 UM146_RS22165 4463134 4463772 - peptide methionine sulfoxide reductase MsrA this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form%3B provides protection against oxidative stress gene gene4415 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22165 UM146_RS22170 UM146_RS22170 UM146_RS22170 4463847 4464008 + hypothetical protein gene gene4416 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22170 UM146_RS22175 UM146_21380 UM146_RS22175 4463978 4465711 + membrane protein gene gene4417 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22175 UM146_RS22180 UM146_21385 UM146_RS22180 4465708 4469487 + hypothetical protein gene gene4418 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22180 UM146_RS22185 UM146_21390 UM146_RS22185 4469490 4469831 + gamma-glutamylcyclotransferase YtfP gene gene4419 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22185 UM146_RS22190 UM146_21395 UM146_RS22190 4470210 4470740 - inorganic pyrophosphatase catalyzes the hydrolysis of pyrophosphate to phosphate gene gene4420 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22190 UM146_RS22195 UM146_21400 UM146_RS22195 4471050 4472006 + sugar ABC transporter substrate-binding protein gene gene4421 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22195 UM146_RS22200 UM146_21405 UM146_RS22200 4472146 4473648 + sugar ABC transporter ATP-binding protein gene gene4422 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22200 UM146_RS22205 UM146_21410 UM146_RS22205 4473662 4474684 + sugar ABC transporter permease gene gene4423 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22205 UM146_RS22210 UM146_21415 UM146_RS22210 4474671 4475666 + sugar ABC transporter permease membrane component of a putative sugar ABC transporter system gene gene4424 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22210 UM146_RS22215 UM146_21420 UM146_RS22215 4475699 4476697 - fructose 1%2C6-bisphosphatase catalyzes the formation of D-fructose 6-phosphate from fructose-1%2C6-bisphosphate gene gene4425 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22215 UM146_RS22220 UM146_21425 UM146_RS22220 4476873 4478246 + UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase ligates L-alanyl-gamma-D-glutamyl-meso-diaminopimelate to UDP-N-acetylmuramic acid for reincorporation into peptidoglycan gene gene4426 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22220 UM146_RS22225 UM146_21430 UM146_RS22225 4478404 4478955 - ribosome-associated UPF0307 family protein gene gene4427 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22225 UM146_RS22230 UM146_21435 pmbA pmbA 4479048 4480400 + peptidase PMbA protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD gene gene4428 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22230 UM146_RS22235 UM146_RS22235 UM146_RS22235 4480584 4480970 + cytochrome B562 electron transport protein gene gene4429 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22235 UM146_RS22240 UM146_21445 UM146_RS22240 4481015 4481479 - anaerobic ribonucleoside-triphosphate reductase-activating protein activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions gene gene4430 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22240 UM146_RS22245 UM146_21450 UM146_RS22245 4481637 4483775 - ribonucleoside triphosphate reductase Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates gene gene4431 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22245 UM146_RS22250 UM146_21455 UM146_RS22250 4484046 4484141 + hypothetical protein gene gene4432 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22250 UM146_RS22255 UM146_21460 UM146_RS22255 4484169 4485824 - trehalose-6-phosphate hydrolase gene gene4433 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22255 UM146_RS22260 UM146_21465 UM146_RS22260 4485874 4487292 - PTS maltose transporter subunit IIBC phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene4434 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22260 UM146_RS22265 UM146_21470 treR treR 4487414 4488361 - trehalose repressor regulates genes involved in trehalose metabolism%3B binds the intermediate trehalose-6-phosphate%3B binds a dimer%3B regulates treBC operon gene gene4435 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22265 UM146_RS22270 UM146_21475 UM146_RS22270 4488740 4491436 + magnesium-translocating P-type ATPase P-type%3B involved in magnesium transport into the cytoplasm gene gene4436 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22270 UM146_RS22275 UM146_21480 UM146_RS22275 4491642 4492028 - reactive intermediate/imine deaminase has endoribonuclease activity on mRNA gene gene4437 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22275 UM146_RS22280 UM146_21485 UM146_RS22280 4492101 4492562 - aspartate carbamoyltransferase regulatory chain involved in the allosteric regulation of aspartate carbamoyltransferase gene gene4438 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22280 UM146_RS22285 UM146_21490 UM146_RS22285 4492575 4493510 - aspartate carbamoyltransferase catalytic subunit gene gene4439 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22285 UM146_RS22290 UM146_21495 UM146_RS22290 4493514 4493648 - pyrBI operon leader peptide gene gene4440 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22290 UM146_RS22295 UM146_21500 UM146_RS22295 4493738 4494226 - ArgR family transcriptional regulator gene gene4441 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22295 UM146_RS22300 UM146_21505 UM146_RS22300 4494342 4495745 - C4-dicarboxylate ABC transporter gene gene4442 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22300 UM146_RS22305 UM146_21510 UM146_RS22305 4495802 4496806 - ornithine carbamoyltransferase catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway gene gene4443 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22305 UM146_RS22310 UM146_21515 UM146_RS22310 4496817 4497761 - carbamate kinase reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP gene gene4444 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22310 UM146_RS22315 UM146_21520 UM146_RS22315 4497772 4498992 - arginine deiminase catalyzes the degradation of arginine to citruline and ammonia gene gene4445 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22315 UM146_RS22320 UM146_21525 UM146_RS22320 4499670 4500122 + hypothetical protein gene gene4446 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22320 UM146_RS22325 UM146_21530 UM146_RS22325 4500168 4501172 - ornithine carbamoyltransferase catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway gene gene4447 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22325 UM146_RS22330 UM146_21535 UM146_RS22330 4501334 4501750 + RNase E inhibitor protein gene gene4448 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22330 UM146_RS22335 UM146_21540 UM146_RS22335 4501927 4502430 - N-acetyltransferase gene gene4449 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22335 UM146_RS22340 UM146_21545 UM146_RS22340 4502623 4503810 + membrane protein gene gene4450 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22340 UM146_RS22345 UM146_21550 UM146_RS22345 4503857 4506712 - valine--tRNA ligase gene gene4451 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22345 UM146_RS22350 UM146_21555 UM146_RS22350 4506712 4507155 - DNA polymerase III subunit chi binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB gene gene4452 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22350 UM146_RS22355 UM146_21560 UM146_RS22355 4507413 4508924 - cytosol aminopeptidase catalyzes the removal of N-terminal amino acids preferably from various peptides%3B a cyteinylglycinase%2C transcription regulator and site-specific recombination factor gene gene4453 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22355 UM146_RS22360 UM146_21565 UM146_RS22360 4509191 4510291 + LPS export ABC transporter permease LptF with LptBGC is involved in lipopolysaccharide export gene gene4454 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22360 UM146_RS22365 UM146_21570 UM146_RS22365 4510291 4511373 + LPS export ABC transporter permease LptG with LptABCF is involved in the transport of lipopolysaccharides gene gene4455 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22365 UM146_RS22370 UM146_21575 UM146_RS22370 4511534 4513036 - hypothetical protein gene gene4456 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22370 UM146_RS22375 UM146_21580 UM146_RS22375 4513114 4514112 - transcriptional regulator gene gene4457 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22375 UM146_RS22380 UM146_21585 UM146_RS22380 4514179 4515498 - fructuronate transporter gene gene4458 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22380 UM146_RS22385 UM146_21590 UM146_RS22385 4515563 4516327 - gluconate 5-dehydrogenase Involved in the nonphosphorylative%2C ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate gene gene4459 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22385 UM146_RS22390 UM146_21595 UM146_RS22390 4516351 4517382 - L-idonate 5-dehydrogenase NAD-binding gene gene4460 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22390 UM146_RS22395 UM146_21600 idnK idnK 4517599 4518162 + D-gluconate kinase gene gene4461 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22395 UM146_RS22400 UM146_21605 UM146_RS22400 4518166 4519185 - alcohol dehydrogenase gene gene4462 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22400 UM146_RS22405 UM146_t23977 UM146_RS22405 4519381 4519465 + tRNA-Leu tRNA gene4463 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22405 UM146_RS22410 UM146_21610 UM146_RS22410 4519651 4520913 + integrase gene gene4464 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22410 UM146_RS22415 UM146_21615 UM146_RS22415 4521365 4524880 + DNA helicase gene gene4465 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22415 UM146_RS22420 UM146_21620 UM146_RS22420 4524989 4526488 - metal-dependent hydrolase gene gene4466 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22420 UM146_RS22425 UM146_21625 UM146_RS22425 4526669 4527409 - hypothetical protein gene gene4467 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22425 UM146_RS22430 UM146_21630 UM146_RS22430 4527627 4527995 - membrane protein gene gene4468 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22430 UM146_RS22435 UM146_21635 UM146_RS22435 4528771 4529070 + cobalamin biosynthesis protein gene gene4469 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22435 UM146_RS22440 UM146_RS22440 UM146_RS22440 4529555 4530105 - transcriptional regulator gene gene4470 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22440 UM146_RS22445 UM146_21645 UM146_RS22445 4530368 4531375 - fimbrial protein gene gene4471 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22445 UM146_RS22450 UM146_21650 UM146_RS22450 4531419 4531922 - fimbrial adapter papF gene gene4472 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22450 UM146_RS22455 UM146_21655 UM146_RS22455 4531998 4532519 - fimbrial protein gene gene4473 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22455 UM146_RS22460 UM146_21660 UM146_RS22460 4532546 4533082 - fimbrial adapter papK gene gene4474 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22460 UM146_RS22465 UM146_21665 UM146_RS22465 4533092 4533673 - protein papJ gene gene4475 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22465 UM146_RS22470 UM146_21670 UM146_RS22470 4533710 4534444 - molecular chaperone gene gene4476 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22470 UM146_RS22475 UM146_21675 UM146_RS22475 4534515 4537025 - outer membrane usher protein PapC gene gene4477 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22475 UM146_RS22480 UM146_21680 UM146_RS22480 4537084 4537671 - minor pilin subunit PapH gene gene4478 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22480 UM146_RS22485 UM146_21685 UM146_RS22485 4537734 4538297 - pap fimbrial major pilin protein gene gene4479 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22485 UM146_RS22490 UM146_21690 UM146_RS22490 4538505 4538819 - major pilus subunit operon regulatory protein PapB gene gene4480 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22490 UM146_RS22495 UM146_RS22495 UM146_RS22495 4538806 4538976 - hypothetical protein gene gene4481 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22495 UM146_RS22500 UM146_21695 UM146_RS22500 4539224 4539457 + Major pilus subunit operon regulatory protein gene gene4482 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22500 UM146_RS22505 UM146_21700 UM146_RS22505 4539563 4539793 - hypothetical protein gene gene4483 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22505 UM146_RS22510 UM146_21705 UM146_RS22510 4539960 4540328 + hypothetical protein gene gene4484 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22510 UM146_RS22520 UM146_RS22520 UM146_RS22520 4540897 4541070 + protein encoded within IS gene gene4485 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22520 UM146_RS22525 UM146_21710 UM146_RS22525 4541378 4541854 - LuxR family transcriptional regulator gene gene4486 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22525 UM146_RS22530 UM146_21715 UM146_RS22530 4541917 4542123 - hypothetical protein gene gene4487 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22530 UM146_RS22535 UM146_21725 UM146_RS22535 4542575 4542943 - hypothetical protein gene gene4488 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22535 UM146_RS22540 UM146_21730 UM146_RS22540 4543219 4544298 - fimbrial protein F17 gene gene4489 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22540 UM146_RS22545 UM146_21735 UM146_RS22545 4544295 4546829 - fimbrial protein F17 gene gene4490 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22545 UM146_RS22550 UM146_RS22550 UM146_RS22550 4546837 4547562 - molecular chaperone gene gene4491 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22550 UM146_RS22555 UM146_21745 UM146_RS22555 4547627 4548175 - fimbrial protein gene gene4492 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22555 UM146_RS22560 UM146_21755 UM146_RS22560 4548751 4549173 - membrane protein gene gene4493 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22560 UM146_RS22565 UM146_21760 UM146_RS22565 4549176 4550393 - hypothetical protein gene gene4494 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22565 UM146_RS22570 UM146_21765 UM146_RS22570 4550444 4550992 - hypothetical protein gene gene4495 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22570 UM146_RS22575 UM146_21770 UM146_RS22575 4551162 4551803 + TetR family transcriptional regulator gene gene4496 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22575 UM146_RS22585 UM146_21780 UM146_RS22585 4552659 4552844 - transposase gene gene4497 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22585 UM146_RS22590 UM146_21785 UM146_RS22590 4552908 4554041 + transposase gene gene4498 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22590 UM146_RS22595 UM146_21790 UM146_RS22595 4554151 4555719 - transposase gene gene4499 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22595 UM146_RS22600 UM146_21795 UM146_RS22600 4555750 4556100 - isocitrate lyase gene gene4500 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22600 UM146_RS22605 UM146_21800 UM146_RS22605 4556097 4556525 - transposase gene gene4501 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22605 UM146_RS22610 UM146_RS22610 UM146_RS22610 4557032 4557226 - hypothetical protein gene gene4502 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22610 UM146_RS22615 UM146_21815 UM146_RS22615 4557431 4557730 - transposase gene gene4503 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22615 UM146_RS22620 UM146_21820 UM146_RS22620 4557824 4558276 + transposase gene gene4504 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22620 UM146_RS22625 UM146_RS22625 UM146_RS22625 4558317 4558529 - hypothetical protein gene gene4505 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22625 UM146_RS22630 UM146_21825 UM146_RS22630 4558650 4561694 - cytotoxin gene gene4506 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22630 UM146_RS22635 UM146_21830 UM146_RS22635 4561972 4562199 - hypothetical protein gene gene4507 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22635 UM146_RS22640 UM146_21835 UM146_RS22640 4562640 4564076 - hemolysin D gene gene4508 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22640 UM146_RS22645 UM146_21840 UM146_RS22645 4564095 4566218 - alpha-hemolysin translocation ATP-binding protein HlyB gene gene4509 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22645 UM146_RS22650 UM146_21845 UM146_RS22650 4566289 4569363 - exotoxin paxA gene gene4510 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22650 UM146_RS22655 UM146_21850 UM146_RS22655 4569375 4569887 - hemolysin-activating lysine-acyltransferase hlyC gene gene4511 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22655 UM146_RS22660 UM146_21855 UM146_RS22660 4571071 4571313 - hypothetical protein gene gene4512 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22660 UM146_RS22665 UM146_21860 UM146_RS22665 4571341 4572111 - hypothetical protein gene gene4513 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22665 UM146_RS22670 UM146_21865 UM146_RS22670 4572111 4572710 - thioredoxin reductase gene gene4514 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22670 UM146_RS22675 UM146_21870 UM146_RS22675 4572850 4573569 + two-component system response regulator gene gene4515 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22675 UM146_RS22680 UM146_21875 UM146_RS22680 4573570 4575042 + two-component system sensor histidine kinase gene gene4516 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22680 UM146_RS22685 UM146_RS22685 UM146_RS22685 4575122 4575316 - transposase gene gene4517 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22685 UM146_RS22690 UM146_21890 UM146_RS22690 4575971 4576291 - transposase gene gene4518 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22690 UM146_RS22695 UM146_21895 UM146_RS22695 4576320 4576520 - transposase gene gene4519 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22695 UM146_RS22700 UM146_RS22700 UM146_RS22700 4577267 4578849 - hypothetical protein gene gene4520 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22700 UM146_RS22705 UM146_RS22705 UM146_RS22705 4578947 4581906 - ATPase gene gene4521 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22705 UM146_RS22710 UM146_21920 UM146_RS22710 4581911 4582957 - DNA-cytosine methyltransferase gene gene4522 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22710 UM146_RS22715 UM146_RS22715 UM146_RS22715 4583338 4583694 - hypothetical protein gene gene4523 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22715 UM146_RS22720 UM146_RS22720 UM146_RS22720 4583704 4584135 - hypothetical protein gene gene4524 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22720 UM146_RS22725 UM146_21935 UM146_RS22725 4584215 4584550 - hypothetical protein gene gene4525 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22725 UM146_RS22730 UM146_21940 UM146_RS22730 4584540 4584803 - hypothetical protein gene gene4526 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22730 UM146_RS22735 UM146_21945 UM146_RS22735 4584852 4585175 - hypothetical protein gene gene4527 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22735 UM146_RS22740 UM146_21950 UM146_RS22740 4585260 4585646 - immunity protein CdiI gene gene4528 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22740 UM146_RS22745 UM146_21955 UM146_RS22745 4585643 4595431 - hypothetical protein gene gene4529 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22745 UM146_RS22750 UM146_21960 UM146_RS22750 4595444 4597210 - peptide transporter gene gene4530 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22750 UM146_RS22755 UM146_21965 UM146_RS22755 4597574 4597807 - hypothetical protein gene gene4531 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22755 UM146_RS22760 UM146_21970 UM146_RS22760 4597905 4598528 - DNA-binding protein gene gene4532 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22760 UM146_RS22765 UM146_21980 UM146_RS22765 4599611 4599844 - regulator gene gene4533 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22765 UM146_RS22770 UM146_21985 UM146_RS22770 4599913 4600473 - hypothetical protein gene gene4534 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22770 UM146_RS22775 UM146_21990 UM146_RS22775 4600720 4601286 - hypothetical protein gene gene4535 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22775 UM146_RS22780 UM146_21995 UM146_RS22780 4602397 4603725 - D-serine dehydratase 2 catalyzes the formation of pyruvate from serine gene gene4536 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22780 UM146_RS22785 UM146_22000 UM146_RS22785 4603743 4605080 - permease gene gene4537 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22785 UM146_RS22790 UM146_RS22790 UM146_RS22790 4605297 4606217 + transcriptional regulator regulates the synthesis and expression of the dsdXA operon and dadA gene gene gene4538 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22790 UM146_RS22795 UM146_RS22795 UM146_RS22795 4606522 4606689 + transposase gene gene4539 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22795 UM146_RS22800 UM146_RS22800 UM146_RS22800 4606655 4606774 + transposase gene gene4540 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22800 UM146_RS22805 UM146_22015 UM146_RS22805 4606913 4607242 - multidrug transporter gene gene4541 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22805 UM146_RS22810 UM146_22020 UM146_RS22810 4607258 4607659 - transporter gene gene4542 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22810 UM146_RS22815 UM146_22025 UM146_RS22815 4607692 4608357 - hypothetical protein gene gene4543 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22815 UM146_RS22820 UM146_22030 UM146_RS22820 4608369 4608989 - propanediol utilization phosphotransacylase gene gene4544 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22820 UM146_RS22825 UM146_22035 UM146_RS22825 4608986 4609450 - microcompartment protein gene gene4545 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22825 UM146_RS22830 UM146_22040 UM146_RS22830 4609462 4610409 - choline TMA-lyase-activating enzyme gene gene4546 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22830 UM146_RS22835 UM146_22045 UM146_RS22835 4610461 4613847 - choline trimethylamine-lyase gene gene4547 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22835 UM146_RS22840 UM146_22050 UM146_RS22840 4613874 4615028 - alcohol dehydrogenase gene gene4548 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22840 UM146_RS22845 UM146_22055 UM146_RS22845 4615044 4615301 - ethanolamine utilization protein EutN gene gene4549 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22845 UM146_RS22850 UM146_22060 UM146_RS22850 4615328 4616914 - acetaldehyde dehydrogenase gene gene4550 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22850 UM146_RS22855 UM146_22065 UM146_RS22855 4616968 4617246 - hypothetical protein gene gene4551 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22855 UM146_RS22860 UM146_22070 UM146_RS22860 4617261 4617545 - hypothetical protein gene gene4552 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22860 UM146_RS22865 UM146_22075 UM146_RS22865 4617563 4617841 - hypothetical protein gene gene4553 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22865 UM146_RS22870 UM146_RS22870 UM146_RS22870 4618022 4618282 + hypothetical protein gene gene4554 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22870 UM146_RS22875 UM146_22080 UM146_RS22875 4618361 4618879 - hypothetical protein gene gene4555 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22875 UM146_RS22880 UM146_22085 UM146_RS22880 4618879 4619697 - transcriptional regulator gene gene4556 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22880 UM146_RS22885 UM146_22090 UM146_RS22885 4619720 4620298 - TetR family transcriptional regulator gene gene4557 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22885 UM146_RS22890 UM146_RS22890 UM146_RS22890 4620489 4620623 - transposase gene gene4558 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22890 UM146_RS22895 UM146_22095 UM146_RS22895 4620589 4621476 - transposase gene gene4559 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22895 UM146_RS22900 UM146_22100 UM146_RS22900 4621476 4621802 - transposase gene gene4560 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22900 UM146_RS22905 UM146_22105 UM146_RS22905 4622276 4623454 + aminotransferase gene gene4561 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22905 UM146_RS22910 UM146_22110 UM146_RS22910 4623447 4624898 + sodium:proton antiporter gene gene4562 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22910 UM146_RS22915 UM146_RS22915 UM146_RS22915 4625824 4626177 + transposase gene gene4563 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22915 UM146_RS22920 UM146_22125 UM146_RS22920 4626212 4627090 - restriction endonuclease gene gene4564 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22920 UM146_RS22925 UM146_22130 UM146_RS22925 4627418 4628149 - transposase gene gene4565 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22925 UM146_RS22930 UM146_22135 UM146_RS22930 4628571 4628840 - hypothetical protein gene gene4566 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22930 UM146_RS22935 UM146_22140 UM146_RS22935 4629632 4630855 - hypothetical protein gene gene4567 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22935 UM146_RS22940 UM146_22145 UM146_RS22940 4630956 4631840 + GTPase gene gene4568 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22940 UM146_RS22945 UM146_22150 UM146_RS22945 4631859 4632014 + hypothetical protein gene gene4569 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22945 UM146_RS22950 UM146_22155 UM146_RS22950 4632043 4632723 + transcriptional regulator gene gene4570 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22950 UM146_RS22955 UM146_22160 UM146_RS22955 4632871 4633548 + membrane protein gene gene4571 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22955 UM146_RS22960 UM146_22165 UM146_RS22960 4633554 4633787 + hypothetical protein gene gene4572 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22960 UM146_RS22965 UM146_22170 UM146_RS22965 4633877 4634695 + hypothetical protein gene gene4573 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22965 UM146_RS22970 UM146_22175 UM146_RS22970 4634786 4635271 + hypothetical protein gene gene4574 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22970 UM146_RS22975 UM146_22180 UM146_RS22975 4635286 4635762 + hypothetical protein gene gene4575 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22975 UM146_RS22980 UM146_22185 UM146_RS22980 4635849 4636070 + hypothetical protein gene gene4576 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22980 UM146_RS22985 UM146_22190 UM146_RS22985 4636150 4636518 + antitoxin gene gene4577 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22985 UM146_RS22990 UM146_22195 UM146_RS22990 4636608 4636985 + toxin gene gene4578 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22990 UM146_RS22995 UM146_22200 UM146_RS22995 4636982 4637470 + hypothetical protein gene gene4579 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS22995 UM146_RS23000 UM146_22205 UM146_RS23000 4637482 4637679 + hypothetical protein gene gene4580 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23000 UM146_RS23005 UM146_22215 UM146_RS23005 4638928 4640903 + hypothetical protein gene gene4581 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23005 UM146_RS23010 UM146_RS23010 UM146_RS23010 4641302 4641481 - endonuclease gene gene4582 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23010 UM146_RS23015 UM146_22225 UM146_RS23015 4641526 4642398 - restriction endonuclease gene gene4583 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23015 UM146_RS23020 UM146_22230 UM146_RS23020 4642609 4643589 - 9-O-acetyl-N-acetylneuraminic acid deacetylase gene gene4584 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23020 UM146_RS23025 UM146_22235 UM146_RS23025 4643654 4644760 - N-acetylneuraminate epimerase gene gene4585 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23025 UM146_RS23030 UM146_22240 UM146_RS23030 4644780 4645328 - porin gene gene4586 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23030 UM146_RS23035 UM146_RS23035 UM146_RS23035 4645867 4646013 + hypothetical protein gene gene4587 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23035 UM146_RS23040 UM146_RS23040 UM146_RS23040 4646295 4646552 - hypothetical protein gene gene4588 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23040 UM146_RS23045 UM146_22250 UM146_RS23045 4646962 4647564 + tyrosine recombinase gene gene4589 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23045 UM146_RS23050 UM146_22255 UM146_RS23050 4648042 4648638 + tyrosine recombinase inversion of on/off regulator of fimA gene gene4590 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23050 UM146_RS23055 UM146_RS23055 UM146_RS23055 4648716 4648931 - hypothetical protein gene gene4591 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23055 UM146_RS23060 UM146_22260 fimA fimA 4649118 4649672 + type-1 fimbrial protein subunit A gene gene4592 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23060 UM146_RS23065 UM146_22265 UM146_RS23065 4649779 4650276 + fimbrin fimI gene gene4593 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23065 UM146_RS23070 UM146_22270 UM146_RS23070 4650313 4651038 + chaperone protein FimC gene gene4594 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23070 UM146_RS23075 UM146_22275 UM146_RS23075 4651104 4653740 + fimbrial protein FimD gene gene4595 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23075 UM146_RS23080 UM146_22280 UM146_RS23080 4653750 4654280 + fimbrial protein FimF gene gene4596 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23080 UM146_RS23085 UM146_22285 UM146_RS23085 4654293 4654796 + fimbrial protein FimG gene gene4597 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23085 UM146_RS23090 UM146_22290 UM146_RS23090 4654816 4655718 + fimbrial protein FimH gene gene4598 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23090 UM146_RS23095 UM146_RS23095 UM146_RS23095 4656265 4656495 + hypothetical protein gene gene4599 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23095 UM146_RS23100 UM146_22295 UM146_RS23100 4656447 4657631 + mannonate dehydratase catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate gene gene4600 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23100 UM146_RS23105 UM146_22300 UM146_RS23105 4657712 4659172 + D-mannonate oxidoreductase gene gene4601 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23105 UM146_RS23110 UM146_RS23110 UM146_RS23110 4659194 4659388 - hypothetical protein gene gene4602 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23110 UM146_RS23115 UM146_22305 UM146_RS23115 4659387 4660160 + transcriptional regulator regulates the expression of uxuBA gene gene4603 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23115 UM146_RS23120 UM146_RS23120 UM146_RS23120 4660474 4660608 + hypothetical protein gene gene4604 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23120 UM146_RS23125 UM146_22310 iraD iraD 4660574 4660957 + anti-adapter protein IraD inhibitor of RssB activity in response to DNA damage%3B blocks degradation of stationary phase sigma factor RpoS gene gene4605 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23125 UM146_RS23130 UM146_22315 UM146_RS23130 4661005 4663386 - phosphoenolpyruvate-protein phosphotransferase gene gene4606 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23130 UM146_RS23135 UM146_22320 UM146_RS23135 4663390 4664022 - dihydroxyacetone kinase subunit DhaL gene gene4607 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23135 UM146_RS23140 UM146_22325 UM146_RS23140 4664035 4665099 - dihydroxyacetone kinase subunit DhaK with DhaL and DhaM forms dihydroxyacetone kinase%2C which is responsible for phosphorylating dihydroxyacetone%3B DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase gene gene4608 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23140 UM146_RS23145 UM146_22330 gldA gldA 4665424 4666506 + glycerol dehydrogenase forms dimers and octamers%3B involved in conversion of glycerol to dihydroxy-acetone gene gene4609 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23145 UM146_RS23150 UM146_22335 UM146_RS23150 4666573 4667841 + MFS transporter gene gene4610 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23150 UM146_RS23155 UM146_22340 UM146_RS23155 4667859 4669223 + pyridine nucleotide-disulfide oxidoreductase gene gene4611 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23155 UM146_RS23160 UM146_22345 UM146_RS23160 4669276 4669500 + hypothetical protein gene gene4612 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23160 UM146_RS23165 UM146_22350 UM146_RS23165 4669524 4671065 + carnitine transporter CniT gene gene4613 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23165 UM146_RS23170 UM146_22355 UM146_RS23170 4671121 4672263 - glycerate kinase gene gene4614 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23170 UM146_RS23175 UM146_22360 UM146_RS23175 4672338 4673225 - 2-hydroxy-3-oxopropionate reductase gene gene4615 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23175 UM146_RS23180 UM146_22365 UM146_RS23180 4673243 4674025 - hydroxypyruvate isomerase gene gene4616 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23180 UM146_RS23185 UM146_22370 UM146_RS23185 4674038 4675777 - glyoxylate carboligase catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate gene gene4617 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23185 UM146_RS23190 UM146_22375 UM146_RS23190 4676171 4678105 + ATPase AAA gene gene4618 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23190 UM146_RS23195 UM146_22380 UM146_RS23195 4678392 4679762 + pyridine nucleotide-disulfide oxidoreductase gene gene4619 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23195 UM146_RS23200 UM146_22385 UM146_RS23200 4679777 4681180 + sodium:proton antiporter gene gene4620 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23200 UM146_RS23205 UM146_22390 UM146_RS23205 4681267 4681995 - transcriptional regulator gene gene4621 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23205 UM146_RS23210 UM146_22400 UM146_RS23210 4682243 4683415 - isoaspartyl dipeptidase gene gene4622 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23210 UM146_RS23215 UM146_22405 UM146_RS23215 4683428 4683889 - hypothetical protein gene gene4623 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23215 UM146_RS23220 UM146_22410 UM146_RS23220 4683886 4684569 - hypothetical protein gene gene4624 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23220 UM146_RS23225 UM146_22415 UM146_RS23225 4684819 4685164 + RNA 2'-phosphotransferase gene gene4625 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23225 UM146_RS23230 UM146_22420 UM146_RS23230 4685199 4685372 + phosphotransferase gene gene4626 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23230 UM146_RS23235 UM146_RS23235 UM146_RS23235 4685385 4686562 - hypothetical protein gene gene4627 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23235 UM146_RS23240 UM146_22435 UM146_RS23240 4686630 4687490 - hypothetical protein gene gene4628 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23240 UM146_RS23245 UM146_22440 UM146_RS23245 4687555 4687812 - hypothetical protein gene gene4629 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23245 UM146_RS23250 UM146_22445 UM146_RS23250 4687809 4688576 - hypothetical protein gene gene4630 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23250 UM146_RS23255 UM146_22450 UM146_RS23255 4688586 4689737 - hypothetical protein gene gene4631 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23255 UM146_RS23260 UM146_22455 UM146_RS23260 4689853 4691133 - membrane protein gene gene4632 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23260 UM146_RS23265 UM146_22460 UM146_RS23265 4691318 4692238 + hypothetical protein gene gene4633 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23265 UM146_RS23275 UM146_22470 UM146_RS23275 4694784 4695125 - hypothetical protein involved in the degradation of RNA%3B may be involved in the recycling of RNA during the SOS response gene gene4636 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23275 UM146_RS23280 UM146_22475 UM146_RS23280 4695354 4696721 - hypothetical protein gene gene4637 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23280 UM146_RS23285 UM146_22480 UM146_RS23285 4696718 4698307 - SAM-dependent methyltransferase gene gene4638 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23285 UM146_RS23290 UM146_22485 UM146_RS23290 4698509 4702021 - DEAD/DEAH box helicase gene gene4639 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23290 UM146_RS23295 UM146_22490 UM146_RS23295 4702209 4703123 + restriction endonuclease gene gene4640 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23295 UM146_RS23300 UM146_22495 UM146_RS23300 4703169 4704125 - GTP-binding protein gene gene4641 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23300 UM146_RS23305 UM146_22500 UM146_RS23305 4704136 4704339 - hypothetical protein gene gene4642 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23305 UM146_RS23310 UM146_22505 UM146_RS23310 4704457 4706607 - carbon starvation protein CstA gene gene4643 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23310 UM146_RS23315 UM146_RS23315 UM146_RS23315 4706652 4706825 - hypothetical protein gene gene4644 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23315 UM146_RS23320 UM146_22510 UM146_RS23320 4706984 4708639 + methyl-accepting chemotaxis protein serine sensor receptor gene gene4645 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23320 UM146_RS23325 UM146_22515 UM146_RS23325 4708682 4709953 - C4-dicarboxylate ABC transporter gene gene4646 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23325 UM146_RS23330 UM146_22520 UM146_RS23330 4709950 4710423 - C4-dicarboxylate ABC transporter permease gene gene4647 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23330 UM146_RS23335 UM146_RS23335 UM146_RS23335 4710487 4711457 - C4-dicarboxylate ABC transporter gene gene4648 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23335 UM146_RS23340 UM146_22535 UM146_RS23340 4712148 4713800 + sodium:proton antiporter gene gene4649 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23340 UM146_RS23345 UM146_22540 UM146_RS23345 4713971 4714876 - GntR family transcriptional regulator gene gene4650 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23345 UM146_RS23350 UM146_22545 UM146_RS23350 4715015 4716037 + galactonate oxidoreductase gene gene4651 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23350 UM146_RS23355 UM146_22550 UM146_RS23355 4716177 4718468 - phosphoglycerol transferase I catalyzes the transfer of phosphoglycerol to the glucan backbone gene gene4652 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23355 UM146_RS23360 UM146_22555 UM146_RS23360 4718722 4719213 - hypothetical protein gene gene4653 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23360 UM146_RS23365 UM146_22560 UM146_RS23365 4719265 4720002 - DNA replication protein DnaC acts to load the DnaB helicase onto the initiation site during DNA replication gene gene4654 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23365 UM146_RS23370 UM146_22565 UM146_RS23370 4720005 4720544 - primosomal protein 1 This protein is required for primosome-dependent normal DNA replication%3B it is also involved in inducing stable DNA replication during SOS response. It forms%2C in concert with dnaB protein and other prepriming proteins dnaC%2C N%2C N'%2C N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' gene gene4655 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23370 UM146_RS23375 UM146_22570 UM146_RS23375 4720652 4721125 - hypothetical protein gene gene4656 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23375 UM146_RS23380 UM146_22575 UM146_RS23380 4721116 4721886 - membrane protein gene gene4657 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23380 UM146_RS23385 UM146_22580 UM146_RS23385 4722506 4723231 + LuxR family transcriptional regulator gene gene4658 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23385 UM146_RS23390 UM146_22585 UM146_RS23390 4723189 4723866 + transcriptional regulator regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin gene gene4659 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23390 UM146_RS23395 UM146_22590 UM146_RS23395 4723904 4724692 - ferric iron reductase involved in ferric hydroximate transport gene gene4660 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23395 UM146_RS23400 UM146_22595 UM146_RS23400 4724794 4725069 + hypothetical protein gene gene4661 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23400 UM146_RS23405 UM146_t23979 UM146_RS23405 4725108 4725194 - tRNA-Leu tRNA gene4662 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23405 UM146_RS23410 UM146_t23981 UM146_RS23410 4725229 4725317 - tRNA-Leu tRNA gene4663 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23410 UM146_RS23415 UM146_t23983 UM146_RS23415 4725345 4725431 - tRNA-Leu tRNA gene4664 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23415 UM146_RS23420 UM146_22600 UM146_RS23420 4725497 4725619 - hypothetical protein gene gene4665 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23420 UM146_RS23425 UM146_22605 rsmC rsmC 4725631 4726662 - ribosomal RNA small subunit methyltransferase C 16S rRNA M2G1207 methyltransferase%3B one of many enzymes that modify bases of the ribosomal RNA%3B this enzyme methylates the G at position 1207 of the small ribosomal subunit gene gene4666 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23425 UM146_RS23430 UM146_22610 UM146_RS23430 4726765 4727178 + DNA polymerase III subunit psi with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB gene gene4667 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23430 UM146_RS23435 UM146_22615 rimI rimI 4727147 4727593 + ribosomal-protein-alanine acetyltransferase alanine acetyltransferase that specifically acetylates ribosomal protein S18 gene gene4668 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23435 UM146_RS23440 UM146_22620 UM146_RS23440 4727608 4728285 + dUMP phosphatase manganese-dependent 5'-nucleotidase%3B specific for 5'-UMP%2C 5'-dUMP%2C and 5'-dTMP%3B member of haloacid dehalogenase (HAD)-like hydrolase superfamily gene gene4669 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23440 UM146_RS23445 UM146_22625 prfC prfC 4728376 4729965 + peptide chain release factor 3 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred%3B GDP/GTP-binding protein gene gene4670 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23445 UM146_RS23450 UM146_22630 UM146_RS23450 4730358 4730963 + osmotically-inducible protein Y gene gene4671 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23450 UM146_RS23455 UM146_22635 UM146_RS23455 4731090 4731251 + hypothetical protein gene gene4672 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23455 UM146_RS23460 UM146_22640 UM146_RS23460 4731373 4732446 + hypothetical protein gene gene4673 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23460 UM146_RS23465 UM146_22645 UM146_RS23465 4732443 4733222 + deoxyribonuclease gene gene4674 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23465 UM146_RS23470 UM146_22650 UM146_RS23470 4733439 4734302 - glycine radical enzyme activase gene gene4675 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23470 UM146_RS23475 UM146_22655 UM146_RS23475 4734274 4735824 - hypothetical protein gene gene4676 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23475 UM146_RS23480 UM146_22660 UM146_RS23480 4735876 4735977 + hypothetical protein gene gene4677 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23480 UM146_RS23485 UM146_22665 UM146_RS23485 4736082 4736861 + deoxyribose-phosphate aldolase catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate gene gene4678 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23485 UM146_RS23490 UM146_22670 UM146_RS23490 4736939 4738261 + thymidine phosphorylase gene gene4679 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23490 UM146_RS23495 UM146_22675 UM146_RS23495 4738313 4739536 + phosphopentomutase gene gene4680 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23495 UM146_RS23500 UM146_22680 deoD deoD 4739593 4740312 + purine nucleoside phosphorylase catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate gene gene4681 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23500 UM146_RS23505 UM146_22685 UM146_RS23505 4740479 4741810 + transcriptional regulator gene gene4682 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23505 UM146_RS23510 UM146_22690 lplA lplA 4741811 4742827 - lipoate-protein ligase A Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins gene gene4683 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23510 UM146_RS23515 UM146_22695 UM146_RS23515 4742855 4743499 - membrane protein gene gene4684 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23515 UM146_RS23520 UM146_22700 serB serB 4743605 4744573 + phosphoserine phosphatase catalyzes the formation of serine from O-phosphoserine gene gene4685 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23520 UM146_RS23525 UM146_22705 UM146_RS23525 4744622 4746004 + DNA repair protein RadA Sms%3B stabilizes the strand-invasion intermediate during the DNA repair%3B involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents gene gene4686 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23525 UM146_RS23530 UM146_22710 UM146_RS23530 4746025 4747257 + trifunctional NAD biosynthesis/regulator protein NadR catalyzes the formation of NAD(+) from nicotinamide ribonucleotide%3B catalyzes the formation of nicotinamide mononucleotide from nicotinamide riboside%3B also has a regulatory function gene gene4687 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23530 UM146_RS23535 UM146_22715 UM146_RS23535 4747349 4747681 + toxin RelE gene gene4688 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23535 UM146_RS23540 UM146_22720 UM146_RS23540 4747683 4747967 + transcriptional regulator gene gene4689 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23540 UM146_RS23545 UM146_22725 UM146_RS23545 4748023 4749690 - heme ABC transporter ATP-binding protein ChvD%3B in Agrobacterium tumefaciens%2C mutations in both Walker boxes were found to affect virulence gene gene4690 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23545 UM146_RS23550 UM146_22730 UM146_RS23550 4749897 4751834 + murein transglycosylase catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan gene gene4691 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23550 UM146_RS23555 UM146_22735 UM146_RS23555 4751924 4752250 + Trp operon repressor When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription gene gene4692 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23555 UM146_RS23560 UM146_22740 yjjX yjjX 4752323 4752850 - non-canonical purine NTP phosphatase pyrophosphatase%3B has activity against dUTP and dITP%3B the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226%3B in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms%3B in Escherichia coli overexpression of this gene leads to resistance to an HMP analog gene gene4693 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23560 UM146_RS23565 UM146_22745 UM146_RS23565 4752902 4753549 + phosphoglycerate mutase GpmB catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate gene gene4694 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23565 UM146_RS23570 UM146_22750 UM146_RS23570 4753546 4754415 - right origin-binding protein AraC family%3B binds to the right arm of the replication origin oriC gene gene4695 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23570 UM146_RS23575 UM146_22755 UM146_RS23575 4754626 4755099 + protein CreA gene gene4696 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23575 UM146_RS23580 UM146_22760 UM146_RS23580 4755112 4755801 + two-component system response regulator response regulator in two-component regulatory system with CreC%3B CreB protein is phosphorylated by sensor protein phospho-CreC%3B involved in catabolic regulation gene gene4697 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23580 UM146_RS23585 UM146_22765 UM146_RS23585 4755801 4757225 + two-component system sensor histidine kinase part of a two-component regulatory system with CreB or PhoB%3B involved in catabolic regulation gene gene4698 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23585 UM146_RS23590 UM146_22770 UM146_RS23590 4757283 4758635 + membrane protein gene gene4699 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23590 UM146_RS23595 UM146_22775 UM146_RS23595 4758695 4759411 - two-component system response regulator gene gene4700 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23595 UM146_RS23600 UM146_RS23600 UM146_RS23600 4759507 4759647 + hypothetical protein gene gene4701 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23600 UM146_RS23605 UM146_22780 UM146_RS23605 4760047 4760733 + RNA methyltransferase member of the SPOUT superfamily of methyltransferases gene gene4702 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23605 UM146_RS23610 UM146_RS23610 thrL thrL 4760947 4761012 + thr operon leader peptide involved in threonine biosynthesis%3B controls the expression of the thrLABC operon gene gene4703 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23610 UM146_RS23615 UM146_22785 thrA thrA 4761093 4763555 + bifunctional aspartokinase/homoserine dehydrogenase 1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine%3B functions in a number of amino acid biosynthetic pathways gene gene4704 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23615 UM146_RS23620 UM146_22790 UM146_RS23620 4763557 4764489 + homoserine kinase catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate gene gene4705 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23620 UM146_RS23625 UM146_22795 UM146_RS23625 4764490 4765776 + threonine synthase gene gene4706 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23625 UM146_RS23630 UM146_RS23630 UM146_RS23630 4765844 4765993 + hypothetical protein gene gene4707 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23630 UM146_RS23635 UM146_22800 UM146_RS23635 4765990 4766286 + hypothetical protein gene gene4708 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23635 UM146_RS23640 UM146_22805 UM146_RS23640 4766326 4767102 - hypothetical protein gene gene4709 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23640 UM146_RS23645 UM146_22810 UM146_RS23645 4767172 4768602 - sodium:alanine symporter gene gene4710 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23645 UM146_RS23650 UM146_22815 UM146_RS23650 4768881 4769834 + transaldolase B gene gene4711 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23650 UM146_RS23655 UM146_22820 mogA mogA 4769949 4770536 + molybdenum cofactor biosynthesis protein MogA forms a trimer%3B related to eukaryotic protein gephyrin%3B functions during molybdenum cofactor biosynthesis gene gene4712 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23655 UM146_RS23660 UM146_RS23660 UM146_RS23660 4770568 4770705 + hypothetical protein gene gene4713 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23660 UM146_RS23665 UM146_22825 UM146_RS23665 4770741 4771307 - hypothetical protein gene gene4714 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23665 UM146_RS23670 UM146_22830 UM146_RS23670 4771456 4772169 - hypothetical protein gene gene4715 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23670 UM146_RS23675 UM146_22835 UM146_RS23675 4772195 4772599 - hypothetical protein gene gene4716 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23675 UM146_RS23680 UM146_22845 dnaK dnaK 4772971 4774887 + molecular chaperone DnaK heat shock protein 70%3B assists in folding of nascent polypeptide chains%3B refolding of misfolded proteins%3B utilizes ATPase activity to help fold%3B co-chaperones are DnaJ and GrpE%3B multiple copies in some bacteria gene gene4717 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23680 UM146_RS23685 UM146_22850 UM146_RS23685 4774976 4776106 + molecular chaperone DnaJ chaperone Hsp40%3B co-chaperone with DnaK%3B Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins%2C also in an autonomous%2C dnaK-independent fashion gene gene4718 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23685 UM146_RS23690 UM146_22855 UM146_RS23690 4776211 4776363 - protein HokC gene gene4719 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23690 UM146_RS23695 UM146_22860 UM146_RS23695 4776974 4777735 + hypothetical protein gene gene4720 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23695 UM146_RS23700 UM146_22865 UM146_RS23700 4777755 4779248 + arylsulfatase gene gene4721 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23700 UM146_RS23705 UM146_22870 UM146_RS23705 4779377 4780636 + hypothetical protein gene gene4722 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23705 UM146_RS23710 UM146_22875 nhaA nhaA 4780871 4782037 + Na+/H+ antiporter NhaA exports sodium by using the electrochemical proton gradient to allow protons into the cell%3B functions in adaptation to high salinity and alkaline pH%3B activity increases at higher pH%3B downregulated at acidic pH gene gene4723 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23710 UM146_RS23715 UM146_22880 nhaR nhaR 4782103 4783002 + transcriptional regulator Na+/H+ antiporter regulatory protein%3B activates the genes nhaA and osmC gene gene4724 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23715 UM146_RS23720 UM146_RS23720 rpsT rpsT 4783097 4783360 - 30S ribosomal protein S20 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase gene gene4725 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23720 UM146_RS23725 UM146_22890 UM146_RS23725 4783463 4783681 + hypothetical protein gene gene4726 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23725 UM146_RS23730 UM146_22895 UM146_RS23730 4783689 4784630 + bifunctional riboflavin kinase/FMN adenylyltransferase gene gene4727 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23730 UM146_RS23735 UM146_22900 ileS ileS 4784673 4787489 + isoleucine--tRNA ligase IleRS%3B catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile)%3B since isoleucine and other amino acids such as valine are similar%2C there are additional editing function in this enzyme%3B one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile)%3B there are two active sites%2C one for aminoacylation and one for editing%3B class-I aminoacyl-tRNA synthetase family type 1 subfamily%3B some organisms carry two different copies of this enzyme gene gene4728 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23735 UM146_RS23740 UM146_22905 lspA lspA 4787489 4787983 + lipoprotein signal peptidase lipoprotein signal peptidase%3B integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis gene gene4729 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23740 UM146_RS23745 UM146_22910 UM146_RS23745 4788091 4788540 + peptidyl-prolyl cis-trans isomerase rotamase%3B accelerates isomerization of the peptidyl prolyl bond%2C involved in the folding of proteases gene gene4730 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23745 UM146_RS23750 UM146_22915 ispH ispH 4788542 4789492 + 4-hydroxy-3-methylbut-2-enyl diphosphate reductase catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)%3B functions in the nonmevalonate isoprenoid biosynthesis pathway gene gene4731 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23750 UM146_RS23755 UM146_22920 UM146_RS23755 4789558 4790472 + non-specific ribonucleoside hydrolase RihC catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides gene gene4732 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23755 UM146_RS23760 UM146_22925 UM146_RS23760 4790495 4790860 + hypothetical protein gene gene4733 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23760 UM146_RS23765 UM146_22930 UM146_RS23765 4791021 4791842 + 4-hydroxy-tetrahydrodipicolinate reductase catalyzes the reduction of 2%2C3-dihydrodipicolinate to 2%2C3%2C4%2C5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis gene gene4734 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23765 UM146_RS23770 UM146_RS23770 UM146_RS23770 4791854 4792051 - hypothetical protein gene gene4735 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23770 UM146_RS23775 UM146_RS23775 UM146_RS23775 4792085 4792180 - hypothetical protein gene gene4736 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23775 UM146_RS23780 UM146_22935 UM146_RS23780 4792298 4793446 + carbamoyl-phosphate synthase small chain catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways%3B forms an octamer composed of four CarAB dimers gene gene4737 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23780 UM146_RS23785 UM146_22940 carB carB 4793464 4796685 + carbamoyl-phosphate synthase large chain four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate%3B CarB is responsible for the amidotransferase activity gene gene4738 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23785 UM146_RS23790 UM146_RS23790 UM146_RS23790 4796764 4796952 + transposase gene gene4739 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23790 UM146_RS23795 UM146_22945 UM146_RS23795 4796909 4797367 + transposase gene gene4740 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23795 UM146_RS23800 UM146_RS23800 UM146_RS23800 4797404 4797622 - hypothetical protein gene gene4741 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23800 UM146_RS23805 UM146_22950 UM146_RS23805 4797657 4798052 + transcriptional regulator regulator of carnitine metabolism%3B induces the caiTABCDE and fixABCX operons gene gene4742 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23805 UM146_RS23810 UM146_22955 UM146_RS23810 4798171 4798761 - carnitine operon protein CaiE involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities gene gene4743 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23810 UM146_RS23815 UM146_22960 UM146_RS23815 4798767 4799552 - carnitinyl-CoA dehydratase catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA gene gene4744 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23815 UM146_RS23820 UM146_22965 caiC caiC 4799661 4801214 - crotonobetaine/carnitine-CoA ligase gene gene4745 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23820 UM146_RS23825 UM146_22970 UM146_RS23825 4801287 4802504 - L-carnitine CoA-transferase catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA%2C also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine gene gene4746 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23825 UM146_RS23830 UM146_22975 UM146_RS23830 4802632 4803774 - crotonobetainyl-CoA dehydrogenase catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA gene gene4747 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23830 UM146_RS23835 UM146_22980 UM146_RS23835 4803805 4805319 - L-carnitine/gamma-butyrobetaine antiporter catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism gene gene4748 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23835 UM146_RS23840 UM146_22985 UM146_RS23840 4805792 4806562 + protein FixA required for anaerobic carnitine reduction%2C may act to transfer electrons to crotonobetaine reductase gene gene4749 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23840 UM146_RS23845 UM146_22990 UM146_RS23845 4806577 4807518 + protein FixB gene gene4750 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23845 UM146_RS23850 UM146_22995 UM146_RS23850 4807569 4808855 + protein FixC FAD/NAD(P)-binding domain%3B possibly part of an electron transfer system required for anaerobic carnitine reduction gene gene4751 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23850 UM146_RS23855 UM146_23000 UM146_RS23855 4808852 4809139 + ferredoxin-like protein FixX gene gene4752 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23855 UM146_RS23860 UM146_23005 UM146_RS23860 4809198 4810529 + metabolite transporter gene gene4753 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23860 UM146_RS23865 UM146_23010 UM146_RS23865 4810637 4811167 + glutathione-regulated potassium-efflux system ancillary protein KefF Required for full activity of KefC%2C a potassium-proton antiporter gene gene4754 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23865 UM146_RS23870 UM146_23015 UM146_RS23870 4811160 4813022 + glutathione-regulated potassium-efflux system protein KefC transport system that facilitates potassium-efflux gene gene4755 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23870 UM146_RS23875 UM146_23020 folA folA 4813214 4813693 + dihydrofolate reductase catalyzes the reduction of dihydrofolate to tetrahydrofolate gene gene4756 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23875 UM146_RS23880 UM146_23025 UM146_RS23880 4813779 4814012 + antitoxin gene gene4757 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23880 UM146_RS23885 UM146_RS23885 UM146_RS23885 4814015 4814330 + plasmid maintenance protein CcdB gene gene4758 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23885 UM146_RS23890 UM146_23040 apaH apaH 4814327 4815175 - bis(5'-nucleosyl)-tetraphosphatase symmetrical hydrolyzes P(1)%2CP(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP gene gene4759 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23890 UM146_RS23895 UM146_23045 apaG apaG 4815182 4815559 - protein ApaG protein associated with Co2+ and Mg2+ efflux gene gene4760 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23895 UM146_RS23900 UM146_23050 ksgA ksgA 4815562 4816383 - ribosomal RNA small subunit methyltransferase A in Escherichia coli this enzyme catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA%3B mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin%3B members of this protein family have secondary functions gene gene4761 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23900 UM146_RS23905 UM146_23055 pdxA pdxA 4816380 4817369 - 4-hydroxythreonine-4-phosphate dehydrogenase catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) gene gene4762 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23905 UM146_RS23910 UM146_23060 UM146_RS23910 4817369 4818655 - chaperone SurA Chaperone involved in the folding of extracytoplasmic proteins%2C especially OmpA%2C OmpF and LamB gene gene4763 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23910 UM146_RS23915 UM146_23065 UM146_RS23915 4818708 4821062 - LPS-assembly protein LptD is involved in outer membrane permeability gene gene4764 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23915 UM146_RS23920 UM146_23070 djlA djlA 4821317 4822132 + dnaJ-like protein DjlA functions as a co-chaperone with DnaK%3B involved in regulation of colanic acid capsule%3B inner membrane protein%3B dimerized via transmembrane domain%3B J-like domain is cytoplasmic and can functionally substitute for DnaJ%3B stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system gene gene4765 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23920 UM146_RS23925 UM146_23075 UM146_RS23925 4822282 4822941 - 23S rRNA/tRNA pseudouridine synthase A catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs gene gene4766 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23925 UM146_RS23930 UM146_23080 UM146_RS23930 4822953 4825859 - RNA polymerase-associated protein RapA transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP%2C when it is trapped or immobilized on tightly supercoiled DNA gene gene4767 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23930 UM146_RS23935 UM146_23085 UM146_RS23935 4826023 4828374 - DNA polymerase II Has polymerase%2C DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C gene gene4768 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23935 UM146_RS23940 UM146_23090 araD araD 4828449 4829144 - L-ribulose-5-phosphate 4-epimerase catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate%3B links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source gene gene4769 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23940 UM146_RS23945 UM146_23095 UM146_RS23945 4829429 4830931 - L-arabinose isomerase catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism gene gene4770 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23945 UM146_RS23950 UM146_23100 UM146_RS23950 4830942 4832642 - ribulokinase catalyzes the phosphorylation of ribulose to ribulose 5-phosphate gene gene4771 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23950 UM146_RS23955 UM146_23105 UM146_RS23955 4832981 4833826 + transcriptional regulator positive and negative regulator%3B regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose gene gene4772 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23955 UM146_RS23960 UM146_23110 UM146_RS23960 4834340 4835188 + hypothetical protein gene gene4773 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23960 UM146_RS23965 UM146_23115 UM146_RS23965 4835195 4835617 + hypothetical protein gene gene4774 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23965 UM146_RS23970 UM146_23120 UM146_RS23970 4835772 4836536 + membrane protein gene gene4775 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23970 UM146_RS23975 UM146_23125 thiQ thiQ 4836650 4837348 - thiamine import ATP-binding protein ThiQ with TbpA and ThiP is part of the thiamine and TPP transport system gene gene4776 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23975 UM146_RS23980 UM146_23130 thiP thiP 4837332 4838942 - thiamine transporter membrane protein permease%3B with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell%3B repressed in presence of exogenous thiamine gene gene4777 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23980 UM146_RS23985 UM146_23135 tbpA tbpA 4838918 4839901 - thiamine ABC transporter substrate-binding protein part of the thiamine and TPP transport system tbpA-thiPQ gene gene4778 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23985 UM146_RS23990 UM146_23140 UM146_RS23990 4840065 4841720 - transcriptional regulator activates sgrS under glucose-phosphate stress conditions gene gene4779 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23990 UM146_RS23995 UM146_23145 UM146_RS23995 4841809 4841940 + inhibitor of glucose transporter gene gene4780 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS23995 UM146_RS24000 UM146_23150 leuD leuD 4842048 4842653 - 3-isopropylmalate dehydratase small subunit catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis%3B forms a heterodimer of LeuC/D gene gene4781 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24000 UM146_RS24005 UM146_23155 UM146_RS24005 4842664 4844064 - 3-isopropylmalate dehydratase large subunit dehydratase component%2C catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate gene gene4782 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24005 UM146_RS24010 UM146_23160 UM146_RS24010 4844067 4845158 - 3-isopropylmalate dehydrogenase gene gene4783 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24010 UM146_RS24015 UM146_23165 UM146_RS24015 4845158 4846729 - 2-isopropylmalate synthase gene gene4784 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24015 UM146_RS24020 UM146_RS24020 UM146_RS24020 4846821 4846907 - leucine operon leader peptide involved in attenuation control of the leuABCD operon in leucine biosynthesis gene gene4785 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24020 UM146_RS24025 UM146_23170 leuO leuO 4847565 4848509 + leucine transcriptional activator activator for leuABCD operon%3B member of LysR family of transcriptional activators gene gene4786 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24025 UM146_RS24030 UM146_23175 UM146_RS24030 4848826 4850550 + acetolactate synthase catalyzes the formation of 2-acetolactate from pyruvate%2C leucine sensitive gene gene4787 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24030 UM146_RS24035 UM146_23180 ilvH ilvH 4850553 4851044 + acetolactate synthase with IlvI catalyzes the formation of 2-acetolactate from pyruvate%2C the small subunit is required for full activity and valine sensitivity%3B E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates%2C valine sensitivity and affinity for cofactors%3B also known as acetolactate synthase 3 small subunit gene gene4788 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24035 UM146_RS24040 UM146_RS24040 UM146_RS24040 4851056 4851142 + fruR/shl operon leader peptide gene gene4789 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24040 UM146_RS24045 UM146_23185 UM146_RS24045 4851224 4852228 + catabolite repressor/activator binds D-fructose as an inducer%3B involved in regulation of operons for central pathways of carbon metabolism gene gene4790 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24045 UM146_RS24050 UM146_23190 UM146_RS24050 4852830 4853288 + transcriptional regulator MraZ MraZ%3B UPF0040%3B crystal structure shows similarity to AbrB gene gene4791 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24050 UM146_RS24055 UM146_23195 UM146_RS24055 4853290 4854231 + ribosomal RNA small subunit methyltransferase H gene gene4792 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24055 UM146_RS24060 UM146_23200 UM146_RS24060 4854228 4854593 + cell division protein FtsL membrane bound cell division protein at septum containing leucine zipper motif gene gene4793 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24060 UM146_RS24065 UM146_23205 UM146_RS24065 4854609 4856375 + cell division protein FtsI penicillin-binding protein 3%3B transpeptidase involved in septal peptidoglycan synthesis gene gene4794 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24065 UM146_RS24070 UM146_23210 murE murE 4856362 4857849 + UDP-N-acetylmuramoylalanyl-D-glutamate--2%2C 6-diaminopimelate ligase involved in cell wall formation%3B peptidoglycan synthesis%3B cytoplasmic enzyme%3B catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate gene gene4795 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24070 UM146_RS24075 UM146_23215 murF murF 4857846 4859204 + UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase gene gene4796 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24075 UM146_RS24080 UM146_23220 mraY mraY 4859198 4860280 + phospho-N-acetylmuramoyl-pentapeptide transferase First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan gene gene4797 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24080 UM146_RS24085 UM146_23225 murD murD 4860283 4861599 + UDP-N-acetylmuramoylalanine--D-glutamate ligase UDP-N-acetylmuramoylalanine--D-glutamate ligase%3B involved in peptidoglycan biosynthesis%3B cytoplasmic%3B catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation gene gene4798 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24085 UM146_RS24090 UM146_23230 UM146_RS24090 4861599 4862843 + lipid II flippase FtsW gene gene4799 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24090 UM146_RS24095 UM146_23235 murG murG 4862840 4863907 + UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase N-acetylglucosaminyl transferase%3B UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase%3B involved in cell wall formation%3B inner membrane-associated%3B last step of peptidoglycan synthesis gene gene4800 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24095 UM146_RS24100 UM146_23240 UM146_RS24100 4863961 4865436 + UDP-N-acetylmuramate--L-alanine ligase gene gene4801 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24100 UM146_RS24105 UM146_23245 ddl ddl 4865429 4866349 + D-alanine--D-alanine ligase D-alanine--D-alanine ligase%3B DdlA%3B DdlB%3B cytoplasmic%3B catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis%3B there are two forms of this enzyme in Escherichia coli gene gene4802 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24105 UM146_RS24110 UM146_23250 UM146_RS24110 4866351 4867181 + cell division protein FtsQ involved in septum formation gene gene4803 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24110 UM146_RS24115 UM146_23255 ftsA ftsA 4867178 4868440 + cell division protein FtsA ATP-binding involved in recruitment of FtsK to Z ring%3B essential cell division protein%3B colocalizes with FtsZ through direct interaction to the septal ring structure%3B structurally similar to eukaryotic actin%3B binds directly to the cell membrane gene gene4804 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24115 UM146_RS24120 UM146_23260 UM146_RS24120 4868501 4869652 + cell division protein FtsZ GTPase%3B similar structure to tubulin%3B forms ring-shaped polymers at the site of cell division%3B other proteins such as FtsA%2C ZipA%2C and ZapA%2C interact with and regulate FtsZ function gene gene4805 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24120 UM146_RS24125 UM146_23265 lpxC lpxC 4869753 4870670 + UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase zinc-dependent%3B catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis gene gene4806 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24125 UM146_RS24130 UM146_23270 UM146_RS24130 4870900 4871412 + secretion monitor secM translational pause allows for the initiation of secA translation gene gene4807 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24130 UM146_RS24135 UM146_RS24135 secA secA 4871474 4874178 + preprotein translocase subunit SecA functions in protein export%3B can interact with acidic membrane phospholipids and the SecYEG protein complex%3B binds to preproteins%3B binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein%3B ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane%3B additional proteins SecD/F/YajC aid SecA recycling%3B exists in an equilibrium between monomers and dimers%3B may possibly form higher order oligomers%3B proteins in this cluster correspond SecA1%3B SecA2 is not essential and seems to play a role in secretion of a subset of proteins gene gene4808 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24135 UM146_RS24140 UM146_23285 UM146_RS24140 4874238 4874636 + nucleoside triphosphate pyrophosphohydrolase gene gene4809 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24140 UM146_RS24145 UM146_23290 UM146_RS24145 4874724 4874921 - DNA gyrase inhibitor YacG inhibits supercoiling by DNA gyrase by binding to the GyrB subunit gene gene4810 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24145 UM146_RS24150 UM146_23295 UM146_RS24150 4874931 4875674 - cell division protein ZapD gene gene4811 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24150 UM146_RS24155 UM146_23300 coaE coaE 4875674 4876294 - dephospho-CoA kinase catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A%3B involved in coenzyme A biosynthesis gene gene4812 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24155 UM146_RS24160 UM146_23305 UM146_RS24160 4876519 4877562 + GMP reductase catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate gene gene4813 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24160 UM146_RS24165 UM146_23310 UM146_RS24165 4877597 4878799 - type IV pilin biogenesis protein gene gene4814 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24165 UM146_RS24170 UM146_23315 UM146_RS24170 4878789 4880174 - hypothetical protein gene gene4815 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24170 UM146_RS24175 UM146_23320 UM146_RS24175 4880184 4880624 - major pilin subunit gene gene4816 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24175 UM146_RS24180 UM146_RS24180 UM146_RS24180 4880637 4880831 + hypothetical protein gene gene4817 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24180 UM146_RS24185 UM146_23325 UM146_RS24185 4880828 4881721 - nicotinate-nucleotide pyrophosphorylase catalyzes the formation of pyridine-2%2C3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide gene gene4818 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24185 UM146_RS24190 UM146_23330 UM146_RS24190 4881809 4882360 + N-acetyl-anhydromuranmyl-L-alanine amidase gene gene4819 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24190 UM146_RS24195 UM146_23335 UM146_RS24195 4882357 4883211 + hypothetical protein involved in regulation of beta-lactamase%3B putative signaling protein gene gene4820 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24195 UM146_RS24200 UM146_23340 UM146_RS24200 4883254 4884624 - aromatic amino acid transporter AroP gene gene4821 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24200 UM146_RS24205 UM146_23345 UM146_RS24205 4885151 4886932 + HNH nuclease gene gene4822 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24205 UM146_RS24210 UM146_23350 UM146_RS24210 4886935 4887219 + hypothetical protein gene gene4823 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24210 UM146_RS24215 UM146_RS24215 UM146_RS24215 4887387 4887626 + hypothetical protein gene gene4824 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24215 UM146_RS24220 UM146_23355 UM146_RS24220 4887627 4887917 + hypothetical protein gene gene4825 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24220 UM146_RS24225 UM146_RS24225 UM146_RS24225 4888084 4888272 + hypothetical protein gene gene4826 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24225 UM146_RS24230 UM146_23365 UM146_RS24230 4888326 4888616 + hypothetical protein gene gene4827 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24230 UM146_RS24235 UM146_23370 pdhR pdhR 4889072 4889836 + pyruvate dehydrogenase complex repressor activates lctPRD operon%3B autoregulates itself through repression of pdhR-aceEF-lpdA operon%3B regulates pyruvate dehydrogenase complex gene gene4828 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24235 UM146_RS24240 UM146_23375 aceE aceE 4889997 4892660 + pyruvate dehydrogenase E1 component%3B part of pyruvate dehydrogenase%3B forms a complex with DlaT and LpdC gene gene4829 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24240 UM146_RS24245 UM146_23380 aceF aceF 4892675 4894567 + dihydrolipoamide acetyltransferase E2 component of pyruvate dehydrogenase multienzyme complex%3B in Escherichia coli AceF contains three N-terminal lipoyl domains gene gene4830 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24245 UM146_RS24250 UM146_23385 UM146_RS24250 4894775 4896199 + dihydrolipoyl dehydrogenase E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex%3B catalyzes the oxidation of dihydrolipoamide to lipoamide gene gene4831 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24250 UM146_RS24255 UM146_23390 UM146_RS24255 4896441 4898198 - hypothetical protein gene gene4832 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24255 UM146_RS24260 UM146_23395 UM146_RS24260 4898553 4901150 + bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate gene gene4833 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24260 UM146_RS24265 UM146_23400 UM146_RS24265 4901325 4901687 + hypothetical protein gene gene4834 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24265 UM146_RS24270 UM146_23405 UM146_RS24270 4901725 4902519 - S-adenosylmethionine decarboxylase proenzyme S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine gene gene4835 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24270 UM146_RS24275 UM146_23410 UM146_RS24275 4902535 4903401 - polyamine aminopropyltransferase gene gene4836 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24275 UM146_RS24280 UM146_23415 UM146_RS24280 4903507 4903854 - PulS_OutS family protein gene gene4837 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24280 UM146_RS24285 UM146_23420 UM146_RS24285 4904020 4905570 + multicopper oxidase laccase%3B copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification gene gene4838 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24285 UM146_RS24290 UM146_23425 UM146_RS24290 4905617 4908007 - glucose dehydrogenase quinoprotein glucose dehydrogenase%3B catalyzes the formation of D-glucono-1%2C5-lactone from D-glucose and ubiquinone gene gene4839 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24290 UM146_RS24295 UM146_23430 UM146_RS24295 4908213 4908749 + hypoxanthine phosphoribosyltransferase catalyzes the formation of inosine monophosphate from hypoxanthine and 5-phospho-alpha-D-ribose 1-diphosphate gene gene4840 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24295 UM146_RS24300 UM146_23435 UM146_RS24300 4908790 4909452 - carbonic anhydrase catalyzes the interconversion of bicarbonate and carbon dioxide gene gene4841 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24300 UM146_RS24305 UM146_23440 UM146_RS24305 4909561 4910487 + multidrug ABC transporter ATP-binding protein gene gene4842 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24305 UM146_RS24310 UM146_23445 UM146_RS24310 4910484 4911254 + inner membrane transport permease YadH gene gene4843 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24310 UM146_RS24315 UM146_23450 UM146_RS24315 4911359 4911799 + PTS sugar transporter subunit IIA gene gene4844 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24315 UM146_RS24320 UM146_23455 UM146_RS24320 4911863 4913092 + hypothetical protein gene gene4845 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24320 UM146_RS24325 UM146_23460 UM146_RS24325 4913096 4913476 - aspartate 1-decarboxylase gene gene4846 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24325 UM146_RS24330 UM146_23465 UM146_RS24330 4913750 4914634 + hypothetical protein gene gene4847 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24330 UM146_RS24335 UM146_23470 panC panC 4914716 4915567 - pantothenate synthetase catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine gene gene4848 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24335 UM146_RS24340 UM146_23475 panB panB 4915579 4916373 - 3-methyl-2-oxobutanoate hydroxymethyltransferase catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5%2C10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate gene gene4849 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24340 UM146_RS24345 UM146_RS24345 UM146_RS24345 4916485 4917748 - adhesin gene gene4850 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24345 UM146_RS24350 UM146_23485 UM146_RS24350 4917798 4918394 - fimbrial protein gene gene4851 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24350 UM146_RS24355 UM146_23490 UM146_RS24355 4918421 4919026 - fimbrial protein gene gene4852 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24355 UM146_RS24360 UM146_23495 UM146_RS24360 4919041 4919607 - fimbrial protein StaD gene gene4853 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24360 UM146_RS24365 UM146_23500 UM146_RS24365 4919624 4922212 - fimbrial protein similar to the fimbrial usher protein PapC gene gene4854 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24365 UM146_RS24370 UM146_23505 ecpD ecpD 4922247 4922987 - molecular chaperone EcpD gene gene4855 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24370 UM146_RS24375 UM146_23510 UM146_RS24375 4923096 4923686 - fimbrial protein gene gene4856 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24375 UM146_RS24380 UM146_23515 UM146_RS24380 4924048 4924527 - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7%2C8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7%2C8-dihydropteridine and ATP gene gene4857 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24380 UM146_RS24385 UM146_23520 pcnB pcnB 4924524 4925888 - poly(A) polymerase I Polymerase that creates the 3' poly(A) tail found in some mRNA's gene gene4858 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24385 UM146_RS24390 UM146_23525 UM146_RS24390 4925981 4926877 - glutamyl-Q tRNA(Asp) ligase this tRNA synthetase lacks the tRNA anticodon interaction domain%3B instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4%2C5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp%3B the modified tRNA does not bind elongation factor Tu gene gene4859 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24390 UM146_RS24395 UM146_23530 dksA dksA 4926944 4927399 - RNA polymerase-binding transcription factor DksA gene gene4860 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24395 UM146_RS24400 UM146_23535 UM146_RS24400 4927577 4928281 - sugar fermentation stimulation protein A gene gene4861 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24400 UM146_RS24405 UM146_23540 UM146_RS24405 4928296 4928826 - 2'-5' RNA ligase catalyzes the ligation and cleavage of of 2'-5' linkages in RNA gene gene4862 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24405 UM146_RS24410 UM146_23545 UM146_RS24410 4928855 4931329 + RNA helicase similar in sequence to the ATP-dependent RNA helicase HrpA gene gene4863 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24410 UM146_RS24415 UM146_23555 mrcB mrcB 4931423 4933957 + bifunctional glycosyl transferase/transpeptidase penicillin-binding protein 1b%3B contains transglycosylase and transpeptidase activity%3B major enzyme for peptidoglycan biosynthesis in Escherichia coli%3B transmembrane protein%3B forms dimers%3B three variants%2C one of which may be a degradation product%2C while the other appears to result from an alternative initiation site%2C are found within the cell gene gene4864 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24415 UM146_RS24420 UM146_23565 UM146_RS24420 4934177 4936420 + ferrichrome outer membrane transporter involved with the transport of ferrichrome across the outer membrane%3B binds the ferrichrome-iron ligand and interacts with the TonB protein gene gene4865 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24420 UM146_RS24425 UM146_23570 UM146_RS24425 4936471 4937268 + iron(3+)-hydroxamate import ATP-binding protein FhuC part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter gene gene4866 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24425 UM146_RS24430 UM146_23575 UM146_RS24430 4937268 4938158 + iron-hydroxamate transporter substrate-binding subunit Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter%3B binds to all hydroxamate siderophores gene gene4867 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24430 UM146_RS24435 UM146_23580 UM146_RS24435 4938155 4940137 + iron-hydroxamate transporter permease subunit gene gene4868 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24435 UM146_RS24440 UM146_23585 UM146_RS24440 4940172 4941452 - glutamate-1-semialdehyde 2%2C1-aminomutase Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway gene gene4869 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24440 UM146_RS24445 UM146_23590 UM146_RS24445 4941677 4943098 + H+/Cl- exchange transporter ClcA Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation gene gene4870 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24445 UM146_RS24450 UM146_23595 UM146_RS24450 4943180 4943524 + iron-sulfur cluster insertion protein ErpA essential respiratory protein A%3B may be involved in the transfer of iron-sulfur clusters%3B essential for growth using oxygen or alternate electron acceptors gene gene4871 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24450 UM146_RS24455 UM146_23600 UM146_RS24455 4943571 4944194 - hypothetical protein gene gene4872 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24455 UM146_RS24460 UM146_23605 UM146_RS24460 4944232 4945032 - vitamin B12 transporter solute binding component of the vitamin B12 transport system BtuCDF gene gene4873 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24460 UM146_RS24465 UM146_23610 UM146_RS24465 4945025 4945723 - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine gene gene4874 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24465 UM146_RS24470 UM146_23615 dgt dgt 4945807 4947324 + deoxyguanosinetriphosphate triphosphohydrolase forms a homotetramer%3B requires magnesium for activity%3B catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate gene gene4875 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24470 UM146_RS24475 UM146_23620 UM146_RS24475 4947454 4948878 + serine endoprotease protease Do%3B required at high temperature%3B degrades damaged proteins gene gene4876 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24475 UM146_RS24480 UM146_23625 UM146_RS24480 4949056 4950186 + CdaR family transcriptional regulator regulates the expression of the operons for the enzymes involved in galactarate%2C glucarate and glycerate utilization gene gene4877 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24480 UM146_RS24485 UM146_23630 UM146_RS24485 4950240 4950626 - hypothetical protein gene gene4878 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24485 UM146_RS24490 UM146_23635 dapD dapD 4950937 4951761 - 2%2C3%2C4%2C5-tetrahydropyridine-2%2C6-dicarboxylate N-succinyltransferase catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway gene gene4879 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24490 UM146_RS24495 UM146_23640 UM146_RS24495 4951792 4954464 - uridylyltransferase catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein gene gene4880 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24495 UM146_RS24500 UM146_23645 UM146_RS24500 4954526 4955320 - methionine aminopeptidase catalyzes the removal of N-terminal amino acids from peptides and arylamides%3B generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn%2C Fe%2C or Mn gene gene4881 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24500 UM146_RS24505 UM146_23650 UM146_RS24505 4955688 4956413 + 30S ribosomal protein S2 gene gene4882 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24505 UM146_RS24510 UM146_23655 tsf tsf 4956548 4957399 + elongation factor Ts EF-Ts%3B functions during elongation stage of protein translation%3B forms a dimer%3B associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu gene gene4883 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24510 UM146_RS24515 UM146_23660 UM146_RS24515 4957546 4958271 + uridylate kinase gene gene4884 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24515 UM146_RS24520 UM146_23665 frr frr 4958421 4958978 + ribosome-recycling factor Rrf%3B Frr%3B ribosome-recycling factor%3B release factor 4%3B RF4%3B recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G%3B A GTPase-dependent process results in release of 50S from 70S%3B inhibited by release factor RF-1%3B essential for viability%3B structurally similar to tRNAs gene gene4885 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24520 UM146_RS24525 UM146_23670 UM146_RS24525 4959070 4960266 + 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzes the formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose-5-phosphate gene gene4886 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24525 UM146_RS24530 UM146_23675 UM146_RS24530 4960455 4961213 + UDP pyrophosphate synthase catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate gene gene4887 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24530 UM146_RS24535 UM146_23680 cdsA cdsA 4961226 4962083 + CDP-diglyceride synthase catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate gene gene4888 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24535 UM146_RS24540 UM146_23685 UM146_RS24540 4962095 4963447 + zinc metallopeptidase RseP catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response gene gene4889 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24540 UM146_RS24545 UM146_23690 UM146_RS24545 4963477 4965909 + outer membrane protein assembly factor BamA part of a complex with YfgL%2C YfiO%2C and NlpB involved in outer membrane protein biosynthesis%3B involved in the assembly of outer membrane proteins gene gene4890 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24545 UM146_RS24550 UM146_23695 UM146_RS24550 4966031 4966516 + chaperone protein Skp gene gene4891 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24550 UM146_RS24555 UM146_23700 lpxD lpxD 4966520 4967545 + UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis gene gene4892 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24555 UM146_RS24560 UM146_23705 UM146_RS24560 4967650 4968105 + 3-hydroxyacyl-ACP dehydratase gene gene4893 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24560 UM146_RS24565 UM146_23710 UM146_RS24565 4968109 4968897 + acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis gene gene4894 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24565 UM146_RS24570 UM146_23715 lpxB lpxB 4968897 4970045 + lipid-A-disaccharide synthase catalyzes the formation of lipid A disaccharide from UDP-2%2C3-diacylglucosamine and 2%2C3-diacylglucosamine-1-phosphate%2C lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM gene gene4895 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24570 UM146_RS24575 UM146_23720 rnhB rnhB 4970042 4970638 + ribonuclease HII RNH2%3B RNase HII%3B binds manganese%3B endonuclease which specifically degrades the RNA of RNA-DNA hybrids gene gene4896 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24575 UM146_RS24580 UM146_23725 dnaE dnaE 4970675 4974157 + DNA polymerase III subunit alpha catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time%3B main replicative polymerase gene gene4897 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24580 UM146_RS24585 UM146_23730 UM146_RS24585 4974170 4975129 + acetyl-CoA carboxylase carboxyltransferase subunit alpha catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%3B forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits%3B one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein gene gene4898 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24585 UM146_RS24590 UM146_23735 UM146_RS24590 4975227 4977368 + lysine decarboxylase CadA constitutive%3B catalyzes the formation of cadaverine from lysine gene gene4899 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24590 UM146_RS24595 UM146_23740 UM146_RS24595 4977425 4977814 + lyase gene gene4900 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24595 UM146_RS24600 UM146_23745 tilS tilS 4977879 4979177 + tRNA(Ile)-lysidine synthetase Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU%3B ATP-dependent%3B responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase gene gene4901 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24600 UM146_RS24605 UM146_23750 UM146_RS24605 4979225 4979485 - Rho-binding antiterminator Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination gene gene4902 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24605 UM146_RS24610 UM146_23755 UM146_RS24610 4979472 4979672 - hypothetical protein gene gene4903 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24610 UM146_RS24615 UM146_23760 UM146_RS24615 4979838 4980383 + hypothetical protein gene gene4904 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24615 UM146_RS24620 UM146_23765 UM146_RS24620 4980380 4980802 + hypothetical protein gene gene4905 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24620 UM146_RS24625 UM146_23770 UM146_RS24625 4980816 4981526 + lipoprotein involved with copper homeostasis and adhesion gene gene4906 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24625 UM146_RS24630 UM146_23775 UM146_RS24630 4981682 4982506 - hypothetical protein gene gene4907 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24630 UM146_RS24635 UM146_23780 UM146_RS24635 4982559 4984277 - proline--tRNA ligase catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) gene gene4908 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24635 UM146_RS24640 UM146_23785 UM146_RS24640 4984388 4985095 - tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA gene gene4909 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24640 UM146_RS24645 UM146_23790 rcsF rcsF 4985092 4985496 - hypothetical protein gene gene4910 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24645 UM146_RS24650 UM146_23795 metQ metQ 4985614 4986429 - D-methionine-binding lipoprotein MetQ gene gene4911 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24650 UM146_RS24655 UM146_23800 UM146_RS24655 4986469 4987122 - methionine ABC transporter part of the MetNIQ methionine uptake system gene gene4912 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24655 UM146_RS24660 UM146_23805 metN metN 4987115 4988146 - methionine import ATP-binding protein MetN part of the metNIQ transport system for methionine gene gene4913 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24660 UM146_RS24665 UM146_23810 UM146_RS24665 4988334 4988906 + D-glycero-beta-D-manno-heptose-1%2C7-bisphosphate 7-phosphatase Converts the D-glycero-beta-D-manno-heptose 1%2C7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate gene gene4914 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24665 UM146_RS24670 UM146_r24017 UM146_RS24670 4989270 4990825 + 16S ribosomal RNA rRNA gene4915 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24670 UM146_RS24675 UM146_t23985 UM146_RS24675 4990882 4990958 + tRNA-Ile tRNA gene4916 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24675 UM146_RS24680 UM146_t23987 UM146_RS24680 4991001 4991076 + tRNA-Ala tRNA gene4917 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24680 UM146_RS24715 UM146_24036 UM146_RS24715 237 446 - transcriptional regulator with Hns involved in transcriptional regulation of hemolysin%3B non-specific DNA-binding protein which affects the production of multiple proteins gene gene4918 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24715 UM146_RS24720 UM146_24041 UM146_RS24720 492 953 - endonuclease gene gene4919 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24720 UM146_RS24725 UM146_RS24725 UM146_RS24725 1198 1410 - hypothetical protein gene gene4920 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24725 UM146_RS24730 UM146_24046 UM146_RS24730 1539 2099 - fertility inhibition protein gene gene4921 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24730 UM146_RS24735 UM146_24051 UM146_RS24735 2202 3062 - hypothetical protein gene gene4922 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24735 UM146_RS24740 UM146_24056 UM146_RS24740 3121 3867 - conjugal transfer protein TraX gene gene4923 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24740 UM146_RS24745 UM146_24061 UM146_RS24745 3887 9157 - conjugal transfer protein TraI cleaves origin of transfer and unwinds%3B oriT relaxase gene gene4924 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24745 UM146_RS24750 UM146_24066 UM146_RS24750 9157 11301 - conjugal transfer protein TraD type IV secretion system coupling protein%3B similar to F plasmid TraD gene gene4925 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24750 UM146_RS24755 UM146_24071 UM146_RS24755 11352 12089 - hypothetical protein gene gene4926 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24755 UM146_RS24760 UM146_24076 UM146_RS24760 12292 13023 - TraT complement resistance protein gene gene4927 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24760 UM146_RS24765 UM146_24081 UM146_RS24765 13072 13551 - hypothetical protein gene gene4928 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24765 UM146_RS24770 UM146_24086 UM146_RS24770 13573 16395 - conjugal transfer protein TraG gene gene4929 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24770 UM146_RS24775 UM146_24091 UM146_RS24775 16392 17765 - conjugal transfer protein TraH gene gene4930 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24775 UM146_RS24780 UM146_RS24780 UM146_RS24780 17752 18189 - conjugal transfer protein TrbF gene gene4931 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24780 UM146_RS24785 UM146_RS24785 UM146_RS24785 18130 18411 - conjugal transfer protein TrbJ gene gene4932 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24785 UM146_RS24790 UM146_24101 UM146_RS24790 18401 18946 - conjugal transfer protein TrbB gene gene4933 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24790 UM146_RS24795 UM146_24106 UM146_RS24795 18933 19217 - conjugal transfer protein TraQ gene gene4934 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24795 UM146_RS24800 UM146_24111 UM146_RS24800 19298 19633 + toxin ArtA gene gene4935 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24800 UM146_RS24805 UM146_24121 UM146_RS24805 19969 20712 - conjugal transfer protein TraF type IV secretion system pilus assembly protein%3B similar to F plasmid TraF gene gene4936 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24805 UM146_RS24810 UM146_24126 UM146_RS24810 20705 20962 - conjugal transfer protein TrbE gene gene4937 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24810 UM146_RS24815 UM146_24131 UM146_RS24815 20989 22839 - conjugal transfer protein TraN TraN%3B TrhN%3B involved in stabilizing mating pairs during plasmid conjugation%3B F plasmid TraN appears to recognize OmpA in the recipient cell gene gene4938 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24815 UM146_RS24820 UM146_24136 UM146_RS24820 22836 23474 - conjugal transfer protein TrbC gene gene4939 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24820 UM146_RS24825 UM146_24141 UM146_RS24825 23483 23788 - hypothetical protein gene gene4940 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24825 UM146_RS24830 UM146_RS24830 UM146_RS24830 23818 24811 - conjugal transfer protein TraU gene gene4941 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24830 UM146_RS24835 UM146_24156 UM146_RS24835 24808 25440 - conjugal transfer protein TraW gene gene4942 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24835 UM146_RS24840 UM146_24161 UM146_RS24840 25437 25823 - conjugal transfer protein TrbI gene gene4943 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24840 UM146_RS24845 UM146_24166 UM146_RS24845 25820 28450 - conjugal transfer protein TraC similar to VirB4 gene gene4944 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24845 UM146_RS24850 UM146_24181 UM146_RS24850 29117 29590 - hypothetical protein gene gene4945 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24850 UM146_RS24860 UM146_24191 UM146_RS24860 29939 30454 - conjugal transfer protein TraV gene gene4946 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24860 UM146_RS24865 UM146_24196 UM146_RS24865 30451 30684 - conjugal transfer protein TrbG gene gene4947 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24865 UM146_RS24870 UM146_24201 UM146_RS24870 30696 31016 - conjugal transfer protein TrbD gene gene4948 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24870 UM146_RS24875 UM146_24206 UM146_RS24875 31003 31593 - conjugal transfer protein TraP gene gene4949 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24875 UM146_RS24880 UM146_24211 UM146_RS24880 31583 33010 - conjugal transfer protein TraB gene gene4950 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24880 UM146_RS24885 UM146_24216 UM146_RS24885 33010 33681 - conjugal transfer protein TraK gene gene4951 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24885 UM146_RS24890 UM146_24221 UM146_RS24890 33724 34290 - conjugal transfer protein TraE gene gene4952 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24890 UM146_RS24895 UM146_24226 UM146_RS24895 34312 34623 - conjugal transfer protein TraL gene gene4953 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24895 UM146_RS24900 UM146_24231 UM146_RS24900 34638 34997 - conjugal transfer protein TraA gene gene4954 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24900 UM146_RS24905 UM146_24236 UM146_RS24905 35031 35258 - relaxosome protein TraY gene gene4955 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24905 UM146_RS24910 UM146_24241 UM146_RS24910 35352 36038 - protein TraJ gene gene4956 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24910 UM146_RS24915 UM146_24246 UM146_RS24915 36232 36615 - conjugal transfer protein TraM gene gene4957 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24915 UM146_RS24920 UM146_24251 UM146_RS24920 37039 37548 + lytic transglycosylase gene gene4958 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24920 UM146_RS24925 UM146_24256 UM146_RS24925 37845 38666 - hypothetical protein gene gene4959 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24925 UM146_RS24930 UM146_RS24930 UM146_RS24930 38785 39072 - hypothetical protein gene gene4960 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24930 UM146_RS24935 UM146_RS24935 UM146_RS24935 39097 39216 - hypothetical protein gene gene4961 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24935 UM146_RS24940 UM146_RS24940 UM146_RS24940 39299 39493 - transporter gene gene4962 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24940 UM146_RS24945 UM146_24261 UM146_RS24945 39416 39751 + hypothetical protein gene gene4963 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24945 UM146_RS24950 UM146_24266 UM146_RS24950 39988 40146 - stable plasmid inheritance protein gene gene4964 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24950 UM146_RS24955 UM146_RS24955 UM146_RS24955 40190 40406 + protein sok gene gene4965 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24955 UM146_RS24960 UM146_24276 UM146_RS24960 40422 41141 - recombinase PsiA gene gene4966 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24960 UM146_RS24965 UM146_24281 psiB psiB 41138 41572 - recombinase gene gene4967 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24965 UM146_RS24970 UM146_24286 UM146_RS24970 41627 43585 - hypothetical protein gene gene4968 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24970 UM146_RS24975 UM146_24291 UM146_RS24975 43644 43877 - hypothetical protein gene gene4969 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24975 UM146_RS24980 UM146_24296 UM146_RS24980 43934 44461 - single-stranded DNA-binding protein gene gene4970 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24980 UM146_RS24985 UM146_24301 UM146_RS24985 44763 45221 + hypothetical protein gene gene4971 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24985 UM146_RS24990 UM146_24306 UM146_RS24990 45307 45870 - hypothetical protein gene gene4972 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24990 UM146_RS24995 UM146_24311 UM146_RS24995 45917 47278 - hydrolase gene gene4973 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS24995 UM146_RS25000 UM146_RS25000 UM146_RS25000 47330 47560 - hypothetical protein gene gene4974 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25000 UM146_RS25005 UM146_24321 UM146_RS25005 48522 48713 - hypothetical protein gene gene4975 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25005 UM146_RS25010 UM146_24326 UM146_RS25010 48710 49132 - hypothetical protein gene gene4976 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25010 UM146_RS25015 UM146_24331 UM146_RS25015 49179 49604 - antirestriction protein YubI gene gene4977 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25015 UM146_RS25020 UM146_24341 UM146_RS25020 50020 50790 - hypothetical protein gene gene4978 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25020 UM146_RS25025 UM146_24346 UM146_RS25025 50835 51269 - hypothetical protein gene gene4979 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25025 UM146_RS25030 UM146_24351 UM146_RS25030 51283 51504 - hypothetical protein gene gene4980 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25030 UM146_RS25035 UM146_24356 UM146_RS25035 51505 52188 - methylase gene gene4981 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25035 UM146_RS25040 UM146_RS25040 UM146_RS25040 52264 52575 - hypothetical protein gene gene4982 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25040 UM146_RS25045 UM146_24361 UM146_RS25045 52572 52775 - hypothetical protein gene gene4983 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25045 UM146_RS25050 UM146_24366 UM146_RS25050 52816 53988 + integrase gene gene4984 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25050 UM146_RS25055 UM146_24371 UM146_RS25055 53988 54785 + Insertion sequence IS21 ATP-binding protein gene gene4985 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25055 UM146_RS25060 UM146_24376 UM146_RS25060 54779 55633 - hypothetical protein gene gene4986 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25060 UM146_RS25065 UM146_24386 UM146_RS25065 56028 57248 - transposase gene gene4987 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25065 UM146_RS25070 UM146_24391 UM146_RS25070 57267 57785 - hypothetical protein gene gene4988 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25070 UM146_RS25075 UM146_24396 UM146_RS25075 57920 58168 + protein impC gene gene4989 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25075 UM146_RS25080 UM146_24401 UM146_RS25080 58165 58602 + protein impA' gene gene4990 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25080 UM146_RS25085 UM146_RS25085 UM146_RS25085 58602 59873 + protein ImpB gene gene4991 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25085 UM146_RS25090 UM146_24421 UM146_RS25090 59878 60270 - hypothetical protein gene gene4992 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25090 UM146_RS25095 UM146_24426 UM146_RS25095 60275 61246 - hypothetical protein gene gene4993 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25095 UM146_RS25100 UM146_24431 UM146_RS25100 61475 62119 + chromosome partitioning protein ParA gene gene4994 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25100 UM146_RS25105 UM146_24436 UM146_RS25105 62113 62388 + hypothetical protein gene gene4995 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25105 UM146_RS25110 UM146_RS25110 UM146_RS25110 62526 63334 - resolvase gene gene4996 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25110 UM146_RS25115 UM146_24451 UM146_RS25115 63335 63640 - toxin CcdB controlled cell death protein%3B post-segregation toxin%3B toxin addiction system gene gene4997 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25115 UM146_RS25120 UM146_24456 UM146_RS25120 63642 63860 - antitoxin CcdA gene gene4998 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25120 UM146_RS25125 UM146_RS25125 UM146_RS25125 66182 66823 + hypothetical protein gene gene4999 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25125 UM146_RS25130 UM146_RS25130 UM146_RS25130 67251 67687 + hypothetical protein gene gene5000 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25130 UM146_RS25135 UM146_RS25135 UM146_RS25135 67834 68004 + hypothetical protein gene gene5001 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25135 UM146_RS25140 UM146_24471 UM146_RS25140 67997 68974 + replication protein gene gene5002 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25140 UM146_RS25145 UM146_24476 UM146_RS25145 69217 69957 - recombinase gene gene5003 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25145 UM146_RS25150 UM146_RS25150 UM146_RS25150 70078 70266 - serine/threonine protein kinase gene gene5004 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25150 UM146_RS25155 UM146_RS25155 UM146_RS25155 70633 71801 + hypothetical protein gene gene5005 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25155 UM146_RS25160 UM146_24491 UM146_RS25160 73366 73557 - transposase gene gene5006 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25160 UM146_RS25165 UM146_24496 UM146_RS25165 73515 73880 - transposase represses IS2 gene transcription gene gene5007 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25165 UM146_RS25170 UM146_24501 UM146_RS25170 74162 76132 + ligand-gated channel gene gene5008 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25170 UM146_RS25175 UM146_24506 UM146_RS25175 76139 76930 + ABC transporter gene gene5009 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25175 UM146_RS25185 UM146_24516 UM146_RS25185 77669 78448 - transposase gene gene5011 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25185 UM146_RS25190 UM146_24521 UM146_RS25190 78448 79470 - transposase gene gene5012 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25190 UM146_RS25195 UM146_24526 UM146_RS25195 79556 80242 - transposase gene gene5013 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25195 UM146_RS25200 UM146_24531 UM146_RS25200 80244 80501 - transposase gene gene5014 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25200 UM146_RS25205 UM146_24536 UM146_RS25205 80550 80897 - hypothetical protein gene gene5015 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25205 UM146_RS25210 UM146_24541 UM146_RS25210 80894 81298 - transposase gene gene5016 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25210 UM146_RS25215 UM146_24546 UM146_RS25215 81327 81716 - integrase gene gene5017 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25215 UM146_RS25220 UM146_24551 UM146_RS25220 81800 83308 - group II intron reverse transcriptase/maturase gene gene5018 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25220 UM146_RS25225 UM146_RS25225 UM146_RS25225 83277 83702 + hypothetical protein gene gene5019 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25225 UM146_RS25230 UM146_RS25230 UM146_RS25230 83617 83988 + hypothetical protein gene gene5020 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25230 UM146_RS25235 UM146_24556 UM146_RS25235 83915 84127 - transposase gene gene5021 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25235 UM146_RS25240 UM146_24561 UM146_RS25240 84417 85916 + integrase gene gene5022 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25240 UM146_RS25245 UM146_24566 UM146_RS25245 85913 86668 + ATPase AAA gene gene5023 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25245 UM146_RS25250 UM146_24571 UM146_RS25250 86810 87136 - transposase gene gene5024 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25250 UM146_RS25255 UM146_24576 UM146_RS25255 87201 87467 + transposase gene gene5025 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25255 UM146_RS25260 UM146_24581 UM146_RS25260 87990 89165 - hypothetical protein gene gene5026 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25260 UM146_RS25265 UM146_24586 UM146_RS25265 89234 91495 - colicin Js receptor gene gene5027 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25265 UM146_RS25270 UM146_24591 UM146_RS25270 91664 92440 - biopolymer transporter TonB gene gene5028 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25270 UM146_RS25275 UM146_24596 UM146_RS25275 92448 93323 - hypothetical protein gene gene5029 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25275 UM146_RS25280 UM146_24601 UM146_RS25280 93655 94221 - Rep protein gene gene5030 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25280 UM146_RS25285 UM146_24611 UM146_RS25285 94798 94980 + hypothetical protein gene gene5031 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25285 UM146_RS25290 UM146_24616 UM146_RS25290 95793 96128 - colicin transporter gene gene5032 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25290 UM146_RS25295 UM146_RS25295 UM146_RS25295 96257 96604 + hypothetical protein gene gene5033 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25295 UM146_RS25300 UM146_24621 UM146_RS25300 96624 97133 - hypothetical protein gene gene5034 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25300 UM146_RS25305 UM146_24626 UM146_RS25305 97130 97390 - hypothetical protein gene gene5035 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25305 UM146_RS25310 UM146_24631 UM146_RS25310 97492 97818 + transposase gene gene5036 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25310 UM146_RS25315 UM146_24636 UM146_RS25315 97818 98297 + transposase gene gene5037 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25315 UM146_RS25320 UM146_24641 UM146_RS25320 98904 99392 + transposase gene gene5038 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25320 UM146_RS25325 UM146_24646 UM146_RS25325 99431 99751 - glucose-1-phosphatase gene gene5039 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25325 UM146_RS25330 UM146_24651 UM146_RS25330 99726 100175 - glucose-1-phosphatase gene gene5040 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25330 UM146_RS25335 UM146_24656 UM146_RS25335 100297 100782 - hypothetical protein gene gene5041 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25335 UM146_RS25340 UM146_24661 UM146_RS25340 100807 101292 - thioredoxin gene gene5042 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25340 UM146_RS25345 UM146_24666 UM146_RS25345 101279 101974 - ABC transporter ATP-binding protein gene gene5043 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25345 UM146_RS25350 UM146_24671 UM146_RS25350 101979 103108 - ABC transporter permease gene gene5044 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25350 UM146_RS25355 UM146_24676 UM146_RS25355 103098 104381 - ABC transporter permease gene gene5045 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25355 UM146_RS25360 UM146_24681 UM146_RS25360 104384 105763 - hypothetical protein gene gene5046 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25360 UM146_RS25365 UM146_RS25365 UM146_RS25365 106446 108374 - iron permease gene gene5047 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25365 UM146_RS25370 UM146_24691 UM146_RS25370 108667 109428 - NADH:quinone oxidoreductase gene gene5048 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25370 UM146_RS25375 UM146_24696 UM146_RS25375 109665 110171 - alkyl hydroperoxide reductase gene gene5049 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25375 UM146_RS25380 UM146_24701 UM146_RS25380 110161 110319 - copper-sensitivity suppressor C gene gene5050 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25380 UM146_RS25385 UM146_24706 UM146_RS25385 110418 111122 - transposase gene gene5051 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25385 UM146_RS25390 UM146_RS25390 UM146_RS25390 111265 111476 - hypothetical protein gene gene5052 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25390 UM146_RS25395 UM146_24711 UM146_RS25395 112178 113035 - replication protein RepA gene gene5053 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25395 UM146_RS25400 UM146_RS25400 UM146_RS25400 113028 113102 - positive regulator of RepFIC repA1 expression RepA6 gene gene5054 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25400 UM146_RS25405 UM146_24716 UM146_RS25405 113335 113595 - replication protein gene gene5055 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25405 UM146_RS25410 UM146_24721 UM146_RS25410 113835 114425 - hypothetical protein gene gene5056 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25410 UM146_RS25415 UM146_RS25415 UM146_RS25415 738984 739201 - damage-inducible protein DinI gene gene734 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25415 UM146_RS25420 UM146_RS25420 UM146_RS25420 766758 767006 - hypothetical protein gene gene766 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25420 UM146_RS25425 UM146_RS25425 UM146_RS25425 1433870 1434115 - 50S ribosome-binding GTPase gene gene1402 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25425 UM146_RS25430 UM146_07075 UM146_RS25430 1475559 1475825 - transposase gene gene1447 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25430 UM146_RS25435 UM146_RS25435 UM146_RS25435 2076593 2076886 - hypothetical protein gene gene2033 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25435 UM146_RS25440 UM146_RS25440 UM146_RS25440 2239402 2240222 - antitermination protein gene gene2200 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25440 UM146_RS25445 UM146_RS25445 UM146_RS25445 2248241 2248312 + hypothetical protein gene gene2212 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25445 UM146_RS25450 UM146_13230 UM146_RS25450 2729408 2729587 + hypothetical protein gene gene2723 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25450 UM146_RS25455 UM146_14605 UM146_RS25455 3022045 3022158 - hypothetical protein gene gene3018 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25455 UM146_RS25460 UM146_RS25460 UM146_RS25460 3302451 3302745 - transposase gene gene3283 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25460 UM146_RS25465 UM146_RS25465 UM146_RS25465 3440615 3440818 + hypothetical protein gene gene3437 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25465 UM146_RS25470 UM146_RS25470 UM146_RS25470 3440752 3440937 + hypothetical protein gene gene3438 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25470 UM146_RS25475 UM146_RS25475 UM146_RS25475 4197338 4197585 - hypothetical protein gene gene4156 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25475 UM146_RS25480 UM146_RS25480 UM146_RS25480 4692644 4693526 + hypothetical protein gene gene4634 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25480 UM146_RS25485 UM146_RS25485 UM146_RS25485 4694417 4694737 + hypothetical protein gene gene4635 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25485 UM146_RS25490 UM146_24511 UM146_RS25490 76993 77601 - transposase gene gene5010 http://www.ncbi.nlm.nih.gov/gene/?term=UM146_RS25490