locus-tag	class	description
HXP40_RS00010	COG0592	DNA-directed DNA polymerase activity
HXP40_RS00020	COG0187	DNA topoisomerase II activity
HXP40_RS00025	COG3753	Protein conserved in bacteria
HXP40_RS00030	COG0561	phosphatase activity
HXP40_RS00040	COG2186	Transcriptional regulator
HXP40_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
HXP40_RS00050	COG0800	Aldolase
HXP40_RS00060	COG2271	Major facilitator Superfamily
HXP40_RS00065	COG0644	oxidoreductase
HXP40_RS00070	COG0823	Involved in the tonB-independent uptake of proteins
HXP40_RS00075	COG5645	(Lipo)protein
HXP40_RS00095	COG2188	Transcriptional regulator
HXP40_RS00110	COG2207	Transcriptional regulator
HXP40_RS00115	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HXP40_RS00120	COG3119	arylsulfatase activity
HXP40_RS00130	COG2149	membrane
HXP40_RS00140	COG0641	radical SAM
HXP40_RS00145	COG2814	Major facilitator Superfamily
HXP40_RS00165	COG0028	Belongs to the TPP enzyme family
HXP40_RS00170	COG0440	acetolactate synthase activity
HXP40_RS00175	COG2197	response regulator
HXP40_RS00180	COG3851	Histidine kinase
HXP40_RS00185	COG2271	Major facilitator Superfamily
HXP40_RS00190	COG2271	Major facilitator Superfamily
HXP40_RS00200	COG2252	PERMEase
HXP40_RS00220	COG1464	Belongs to the NlpA lipoprotein family
HXP40_RS00225	COG0697	spore germination
HXP40_RS00230	COG2814	Major facilitator Superfamily
HXP40_RS00240	COG2211	Major facilitator Superfamily
HXP40_RS00245	COG1501	Belongs to the glycosyl hydrolase 31 family
HXP40_RS00250	COG2982	Protein involved in outer membrane biogenesis
HXP40_RS00255	COG2233	PERMEase
HXP40_RS00260	COG0786	glutamate:sodium symporter activity
HXP40_RS00265	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HXP40_RS00270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HXP40_RS00275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HXP40_RS00285	COG0194	GDP metabolic process
HXP40_RS00295	COG2860	membrane
HXP40_RS00300	COG3645	SOS response
HXP40_RS00310	COG1561	YicC-like family, N-terminal region
HXP40_RS00335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HXP40_RS00365	COG1519	Transferase
HXP40_RS00370	COG0859	PFAM glycosyl transferase family 9
HXP40_RS00375	COG0438	transferase activity, transferring glycosyl groups
HXP40_RS00380	COG0515	serine threonine protein kinase
HXP40_RS00385	COG1442	glycosyl transferase family 8
HXP40_RS00390	COG0438	transferase activity, transferring glycosyl groups
HXP40_RS00395	COG1442	glycosyl transferase family 8
HXP40_RS00400	COG1442	glycosyl transferase family 8
HXP40_RS00405	COG3642	lipopolysaccharide core region biosynthetic process
HXP40_RS00425	COG0859	PFAM glycosyl transferase family 9
HXP40_RS00430	COG0859	PFAM glycosyl transferase family 9
HXP40_RS00440	COG0156	8-amino-7-oxononanoate synthase activity
HXP40_RS00450	COG1216	Glycosyl transferase, family 2
HXP40_RS00455	COG2861	carbohydrate metabolic process
HXP40_RS00460	COG4942	peptidase
HXP40_RS00470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HXP40_RS00475	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HXP40_RS00490	COG1045	serine acetyltransferase
HXP40_RS00495	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HXP40_RS00505	COG2186	Transcriptional regulator
HXP40_RS00510	COG1620	l-lactate permease
HXP40_RS00525	COG3722	fumarate hydratase activity
HXP40_RS00535	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HXP40_RS00535	COG2213	PTS system mannitol-specific
HXP40_RS00545	COG1566	PFAM secretion protein HlyD family protein
HXP40_RS00555	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HXP40_RS00570	COG1413	lyase activity
HXP40_RS00575	COG3209	COG3209 Rhs family protein
HXP40_RS00580	COG0625	glutathione transferase activity
HXP40_RS00590	COG3276	selenocysteine insertion sequence binding
HXP40_RS00595	COG1454	alcohol dehydrogenase
HXP40_RS00600	COG1012	belongs to the aldehyde dehydrogenase family
HXP40_RS00615	COG1566	PFAM secretion protein HlyD family protein
HXP40_RS00620	COG0583	DNA-binding transcription factor activity
HXP40_RS00625	COG3713	MltA-interacting MipA family protein
HXP40_RS00640	COG0235	Class ii aldolase
HXP40_RS00645	COG3623	hexulose-6-phosphate isomerase
HXP40_RS00650	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HXP40_RS00655	COG1070	Carbohydrate kinase
HXP40_RS00660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HXP40_RS00665	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HXP40_RS00670	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HXP40_RS00675	COG2731	YhcH YjgK YiaL family protein
HXP40_RS00685	COG1414	Transcriptional regulator
HXP40_RS00690	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HXP40_RS00695	COG3977	Valine--pyruvate aminotransferase
HXP40_RS00700	COG0366	Alpha amylase catalytic
HXP40_RS00705	COG2992	FlgJ-related protein
HXP40_RS00710	COG2207	Transcriptional regulator
HXP40_RS00710	COG1609	Transcriptional regulator
HXP40_RS00715	COG4214	carbohydrate transport
HXP40_RS00720	COG1129	ABC transporter
HXP40_RS00725	COG4213	ABC transporter substrate-binding protein
HXP40_RS00735	COG1070	Carbohydrate kinase
HXP40_RS00740	COG4682	membrane
HXP40_RS00745	COG4682	membrane
HXP40_RS00750	COG3274	enterobacterial common antigen metabolic process
HXP40_RS00780	COG1278	Cold shock
HXP40_RS00785	COG2944	sequence-specific DNA binding
HXP40_RS00800	COG2885	chlorophyll binding
HXP40_RS00805	COG0243	molybdopterin cofactor binding
HXP40_RS00810	COG0456	acetyltransferase
HXP40_RS00815	COG2818	Glycosylase
HXP40_RS00820	COG5571	outer membrane autotransporter
HXP40_RS00825	COG2223	nitrite transmembrane transporter activity
HXP40_RS00830	COG2194	sulfuric ester hydrolase activity
HXP40_RS00840	COG0747	negative chemotaxis
HXP40_RS00845	COG0601	transmembrane transport
HXP40_RS00850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HXP40_RS00855	COG0444	Belongs to the ABC transporter superfamily
HXP40_RS00860	COG4608	Belongs to the ABC transporter superfamily
HXP40_RS00865	COG0814	amino acid
HXP40_RS00875	COG2194	sulfuric ester hydrolase activity
HXP40_RS00900	COG1215	transferase activity, transferring glycosyl groups
HXP40_RS00905	COG1215	transferase activity, transferring glycosyl groups
HXP40_RS00915	COG3118	belongs to the thioredoxin family
HXP40_RS00915	COG0457	Tetratricopeptide repeat
HXP40_RS00920	COG2199	diguanylate cyclase activity
HXP40_RS00920	COG2200	EAL domain
HXP40_RS00930	COG0612	Peptidase, M16
HXP40_RS00935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HXP40_RS00940	COG2200	EAL domain
HXP40_RS00945	COG2982	Protein involved in outer membrane biogenesis
HXP40_RS00950	COG0477	Major facilitator Superfamily
HXP40_RS00955	COG1295	ribonuclease BN
HXP40_RS00960	COG0583	DNA-binding transcription factor activity
HXP40_RS00965	COG2197	response regulator
HXP40_RS00975	COG1858	cytochrome C peroxidase
HXP40_RS00980	COG0076	glutamate decarboxylase activity
HXP40_RS00985	COG2207	Transcriptional regulator
HXP40_RS00990	COG2207	Transcriptional regulator
HXP40_RS00995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HXP40_RS01000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HXP40_RS01010	COG2771	luxR family
HXP40_RS01015	COG3247	response to pH
HXP40_RS01030	COG1285	pathogenesis
HXP40_RS01035	COG2197	response regulator
HXP40_RS01040	COG3065	identical protein binding
HXP40_RS01050	COG1393	Belongs to the ArsC family
HXP40_RS01055	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HXP40_RS01060	COG0640	Transcriptional regulator
HXP40_RS01070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HXP40_RS01075	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HXP40_RS01080	COG0339	signal peptide processing
HXP40_RS01090	COG3104	oligopeptide transport
HXP40_RS01095	COG0589	response to stress
HXP40_RS01105	COG0306	phosphate transporter
HXP40_RS01110	COG2081	HI0933 family
HXP40_RS01130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HXP40_RS01135	COG1129	ABC transporter
HXP40_RS01135	COG0842	Transport permease protein
HXP40_RS01140	COG0842	Transport permease protein
HXP40_RS01145	COG5433	transposase activity
HXP40_RS01160	COG3209	COG3209 Rhs family protein
HXP40_RS01170	COG1124	(ABC) transporter
HXP40_RS01175	COG0444	Belongs to the ABC transporter superfamily
HXP40_RS01180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HXP40_RS01185	COG0601	transmembrane transport
HXP40_RS01190	COG0747	negative chemotaxis
HXP40_RS01195	COG2091	lysine biosynthetic process via aminoadipic acid
HXP40_RS01200	COG0628	permease
HXP40_RS01205	COG0477	Major facilitator Superfamily
HXP40_RS01215	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HXP40_RS01225	COG2217	Heavy metal translocating P-type atpase
HXP40_RS01230	COG3714	YhhN family
HXP40_RS01240	COG3776	membrane
HXP40_RS01245	COG0742	ribosomal rna small subunit methyltransferase
HXP40_RS01250	COG0552	protein localization to endoplasmic reticulum
HXP40_RS01255	COG2884	Cell division ATP-binding protein ftsE
HXP40_RS01260	COG2177	Part of the ABC transporter FtsEX involved in
HXP40_RS01265	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HXP40_RS01270	COG0683	leucine binding
HXP40_RS01275	COG0456	acetyltransferase
HXP40_RS01280	COG0683	leucine binding
HXP40_RS01285	COG0559	Belongs to the binding-protein-dependent transport system permease family
HXP40_RS01290	COG4177	L-phenylalanine transmembrane transporter activity
HXP40_RS01295	COG0411	ABC transporter
HXP40_RS01300	COG0410	ABC transporter
HXP40_RS01305	COG1653	transport
HXP40_RS01310	COG1175	transmembrane transport
HXP40_RS01315	COG0395	ABC-type sugar transport system, permease component
HXP40_RS01320	COG3842	ATPase activity
HXP40_RS01325	COG0584	glycerophosphoryl diester phosphodiesterase
HXP40_RS01335	COG0405	Gamma-glutamyltransferase
HXP40_RS01355	COG3157	Type VI secretion system effector, Hcp
HXP40_RS01360	COG1247	-acetyltransferase
HXP40_RS01365	COG0673	inositol 2-dehydrogenase activity
HXP40_RS01370	COG1741	Belongs to the pirin family
HXP40_RS01375	COG1609	Transcriptional regulator
HXP40_RS01380	COG3265	gluconokinase activity
HXP40_RS01385	COG2610	gluconate transmembrane transporter activity
HXP40_RS01390	COG2095	MarC family integral membrane protein
HXP40_RS01395	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HXP40_RS01420	COG0058	SHG alpha-glucan phosphorylase activity
HXP40_RS01430	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HXP40_RS01445	COG1349	DNA-binding transcription factor activity
HXP40_RS01450	COG4650	regulator
HXP40_RS01455	COG1690	Belongs to the RtcB family
HXP40_RS01470	COG0058	SHG alpha-glucan phosphorylase activity
HXP40_RS01475	COG1640	4-alpha-glucanotransferase
HXP40_RS01480	COG2610	gluconate transmembrane transporter activity
HXP40_RS01490	COG1040	competence protein
HXP40_RS01500	COG5464	transposase or invertase
HXP40_RS01510	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HXP40_RS01515	COG1918	ferrous iron import across plasma membrane
HXP40_RS01520	COG2183	response to ionizing radiation
HXP40_RS01525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HXP40_RS01545	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HXP40_RS01555	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HXP40_RS01560	COG1011	Hydrolase
HXP40_RS01570	COG0494	nUDIX hydrolase
HXP40_RS01575	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HXP40_RS01580	COG4972	Pilus assembly protein
HXP40_RS01585	COG3166	PFAM Fimbrial assembly family protein
HXP40_RS01600	COG4796	Type ii and iii secretion system protein
HXP40_RS01615	COG3266	domain, Protein
HXP40_RS01620	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HXP40_RS01625	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HXP40_RS01630	COG0546	phosphoglycolate phosphatase activity
HXP40_RS01635	COG0180	Tryptophanyl-tRNA synthetase
HXP40_RS01640	COG2188	Transcriptional regulator
HXP40_RS01650	COG3457	Alanine racemase
HXP40_RS01655	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HXP40_RS01660	COG1735	metal-dependent hydrolase with the TIM-barrel fold
HXP40_RS01675	COG0626	cystathionine gamma-synthase activity
HXP40_RS01680	COG2188	Transcriptional regulator
HXP40_RS01685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HXP40_RS01690	COG1082	Xylose isomerase domain protein TIM barrel
HXP40_RS01695	COG2222	sugar isomerase
HXP40_RS01700	COG0531	amino acid
HXP40_RS01715	COG2116	formate transmembrane transporter activity
HXP40_RS01720	COG2146	nitrite reductase [NAD(P)H] activity
HXP40_RS01725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HXP40_RS01735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HXP40_RS01745	COG2184	nucleotidyltransferase activity
HXP40_RS01750	COG0512	Glutamine amidotransferase of anthranilate synthase
HXP40_RS01755	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HXP40_RS01760	COG1289	transmembrane transporter activity
HXP40_RS01765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HXP40_RS01770	COG1765	OsmC-like protein
HXP40_RS01775	COG3954	Phosphoribulokinase
HXP40_RS01785	COG0429	hydrolase of the alpha beta-hydrolase fold
HXP40_RS01790	COG0488	(ABC) transporter
HXP40_RS01805	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HXP40_RS01810	COG1047	Peptidyl-prolyl cis-trans
HXP40_RS01820	COG0545	Peptidyl-prolyl cis-trans isomerase
HXP40_RS01825	COG2964	Protein conserved in bacteria
HXP40_RS01865	COG3979	chitinase
HXP40_RS01870	COG2906	2 iron, 2 sulfur cluster binding
HXP40_RS01875	COG2193	ferroxidase activity
HXP40_RS01880	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HXP40_RS01885	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HXP40_RS01890	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HXP40_RS01895	COG3156	type II secretion system protein K
HXP40_RS01900	COG4795	General secretion pathway protein
HXP40_RS01905	COG2165	general secretion pathway protein
HXP40_RS01910	COG2165	general secretion pathway protein
HXP40_RS01915	COG2165	general secretion pathway protein
HXP40_RS01920	COG1459	type II secretion system
HXP40_RS01925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HXP40_RS01930	COG1450	Type ii and iii secretion system protein
HXP40_RS01935	COG3031	protein transport across the cell outer membrane
HXP40_RS01940	COG3267	Type II secretory pathway component ExeA
HXP40_RS01940	COG3409	Peptidoglycan-binding domain 1 protein
HXP40_RS01965	COG0089	rRNA binding
HXP40_RS02055	COG0201	protein transport
HXP40_RS02095	COG0789	Transcriptional regulator
HXP40_RS02100	COG3036	rescue of stalled ribosome
HXP40_RS02110	COG0569	domain protein
HXP40_RS02130	COG0758	DNA mediated transformation
HXP40_RS02140	COG0551	DNA topoisomerase type I activity
HXP40_RS02160	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HXP40_RS02200	COG1126	abc transporter atp-binding protein
HXP40_RS02205	COG0765	amino acid transport
HXP40_RS02210	COG4597	amino acid ABC transporter
HXP40_RS02215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HXP40_RS02225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HXP40_RS02245	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HXP40_RS02255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HXP40_RS02265	COG4145	pantothenate transmembrane transporter activity
HXP40_RS02270	COG3924	membrane
HXP40_RS02275	COG0439	Biotin carboxylase
HXP40_RS02280	COG0511	ligase activity, forming carbon-carbon bonds
HXP40_RS02285	COG0604	alcohol dehydrogenase
HXP40_RS02290	COG2200	EAL domain
HXP40_RS02290	COG2199	diguanylate cyclase activity
HXP40_RS02295	COG1077	Cell shape determining protein MreB Mrl
HXP40_RS02300	COG1792	Involved in formation and maintenance of cell shape
HXP40_RS02305	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HXP40_RS02310	COG0424	maF-like protein
HXP40_RS02315	COG1530	ribonuclease E activity
HXP40_RS02320	COG3164	Protein of unknown function
HXP40_RS02325	COG0312	modulator of DNA gyrase
HXP40_RS02330	COG0583	DNA-binding transcription factor activity
HXP40_RS02350	COG2732	(Barnase) inhibitor
HXP40_RS02370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HXP40_RS02375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HXP40_RS02380	COG3105	Protein conserved in bacteria
HXP40_RS02385	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HXP40_RS02400	COG0625	glutathione transferase activity
HXP40_RS02405	COG2969	positive regulation of protein catabolic process
HXP40_RS02410	COG3069	C4-dicarboxylate transmembrane transporter activity
HXP40_RS02440	COG2731	YhcH YjgK YiaL family protein
HXP40_RS02445	COG4804	nuclease activity
HXP40_RS02455	COG3344	reverse transcriptase
HXP40_RS02470	COG3539	Fimbrial protein
HXP40_RS02480	COG3188	usher protein
HXP40_RS02485	COG3121	Chaperone
HXP40_RS02490	COG3539	Fimbrial protein
HXP40_RS02495	COG0493	'glutamate synthase
HXP40_RS02500	COG0067	glutamate synthase
HXP40_RS02500	COG0069	glutamate synthase activity
HXP40_RS02500	COG0070	glutamate synthase
HXP40_RS02505	COG1242	4 iron, 4 sulfur cluster binding
HXP40_RS02510	COG5002	protein histidine kinase activity
HXP40_RS02510	COG2198	Histidine kinase
HXP40_RS02510	COG0784	Response regulator, receiver
HXP40_RS02515	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HXP40_RS02525	COG0515	serine threonine protein kinase
HXP40_RS02530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HXP40_RS02545	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HXP40_RS02550	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HXP40_RS02555	COG1137	ATPase activity
HXP40_RS02560	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HXP40_RS02565	COG3117	lipopolysaccharide transmembrane transporter activity
HXP40_RS02570	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HXP40_RS02575	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HXP40_RS02575	COG0517	IMP dehydrogenase activity
HXP40_RS02580	COG0530	calcium, potassium:sodium antiporter activity
HXP40_RS02585	COG1127	ABC transporter
HXP40_RS02590	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HXP40_RS02595	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HXP40_RS02600	COG2854	intermembrane phospholipid transfer
HXP40_RS02605	COG3113	response to antibiotic
HXP40_RS02610	COG5007	Belongs to the BolA IbaG family
HXP40_RS02620	COG3423	Transcriptional regulator
HXP40_RS02625	COG0142	geranyltranstransferase activity
HXP40_RS02640	COG0697	spore germination
HXP40_RS02650	COG2027	D-alanyl-D-alanine carboxypeptidase
HXP40_RS02655	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HXP40_RS02660	COG1534	Rna-binding protein
HXP40_RS02670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HXP40_RS02675	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HXP40_RS02685	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HXP40_RS02695	COG2194	sulfuric ester hydrolase activity
HXP40_RS02715	COG0195	Participates in both transcription termination and antitermination
HXP40_RS02755	COG0513	Belongs to the DEAD box helicase family
HXP40_RS02760	COG0814	amino acid
HXP40_RS02765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HXP40_RS02770	COG0826	peptidase U32
HXP40_RS02775	COG0826	peptidase U32
HXP40_RS02780	COG3154	lipid carrier protein
HXP40_RS02785	COG3153	acetyltransferase
HXP40_RS02800	COG0693	protein deglycase activity
HXP40_RS02805	COG0702	epimerase
HXP40_RS02810	COG0701	Predicted permease
HXP40_RS02815	COG2823	Periplasmic or secreted lipoprotein
HXP40_RS02830	COG3107	peptidoglycan biosynthetic process
HXP40_RS02835	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HXP40_RS02840	COG3539	Fimbrial protein
HXP40_RS02845	COG3188	usher protein
HXP40_RS02850	COG3121	Chaperone
HXP40_RS02855	COG3539	Fimbrial protein
HXP40_RS02860	COG0363	glucosamine-6-phosphate deaminase activity
HXP40_RS02865	COG3716	PTS system mannose fructose sorbose family IID component
HXP40_RS02885	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HXP40_RS02895	COG2222	sugar isomerase
HXP40_RS02900	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HXP40_RS02905	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HXP40_RS02910	COG3716	PTS system mannose fructose sorbose family IID component
HXP40_RS02920	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HXP40_RS02930	COG1349	DNA-binding transcription factor activity
HXP40_RS02940	COG2002	toxin-antitoxin pair type II binding
HXP40_RS02945	COG2721	sulfolactate sulfo-lyase activity
HXP40_RS02950	COG2271	Major facilitator Superfamily
HXP40_RS02960	COG2084	Dehydrogenase
HXP40_RS02965	COG1929	Belongs to the glycerate kinase type-1 family
HXP40_RS02990	COG0583	DNA-binding transcription factor activity
HXP40_RS02995	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HXP40_RS03005	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HXP40_RS03010	COG1882	Formate acetyltransferase
HXP40_RS03015	COG0251	oxidation-reduction process
HXP40_RS03020	COG1760	l-serine dehydratase
HXP40_RS03025	COG0814	amino acid
HXP40_RS03040	COG1741	Belongs to the pirin family
HXP40_RS03045	COG0583	DNA-binding transcription factor activity
HXP40_RS03050	COG3152	Membrane
HXP40_RS03060	COG3152	Membrane
HXP40_RS03065	COG0435	Glutathione S-transferase
HXP40_RS03070	COG2259	Doxx family
HXP40_RS03080	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HXP40_RS03085	COG4575	ribosome binding
HXP40_RS03090	COG1422	Protein of unknown function (DUF1090)
HXP40_RS03100	COG0586	Pfam SNARE associated Golgi protein
HXP40_RS03105	COG2186	Transcriptional regulator
HXP40_RS03110	COG2271	Major facilitator Superfamily
HXP40_RS03120	COG2721	sulfolactate sulfo-lyase activity
HXP40_RS03130	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HXP40_RS03135	COG0861	Integral membrane protein TerC family
HXP40_RS03140	COG0673	inositol 2-dehydrogenase activity
HXP40_RS03145	COG2949	membrane
HXP40_RS03150	COG1451	nucleotide metabolic process
HXP40_RS03160	COG4680	protein conserved in bacteria
HXP40_RS03165	COG5499	transcription regulator containing HTH domain
HXP40_RS03170	COG1902	pentaerythritol trinitrate reductase activity
HXP40_RS03170	COG0446	pyridine nucleotide-disulphide oxidoreductase
HXP40_RS03175	COG3408	Glycogen debranching enzyme
HXP40_RS03175	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HXP40_RS03185	COG0531	amino acid
HXP40_RS03190	COG2731	YhcH YjgK YiaL family protein
HXP40_RS03195	COG3250	beta-galactosidase activity
HXP40_RS03200	COG1609	Transcriptional regulator
HXP40_RS03205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HXP40_RS03215	COG0840	transmembrane signaling receptor activity
HXP40_RS03220	COG1695	Transcriptional regulator
HXP40_RS03225	COG2375	cellular response to nickel ion
HXP40_RS03240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HXP40_RS03245	COG0358	DNA primase activity
HXP40_RS03250	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HXP40_RS03260	COG0471	metal ion transport
HXP40_RS03265	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HXP40_RS03270	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HXP40_RS03275	COG0583	DNA-binding transcription factor activity
HXP40_RS03285	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HXP40_RS03300	COG4991	sh3 domain protein
HXP40_RS03305	COG3025	triphosphatase activity
HXP40_RS03330	COG2268	Band 7 protein
HXP40_RS03340	COG1585	Membrane protein implicated in regulation of membrane protease activity
HXP40_RS03350	COG3539	Fimbrial protein
HXP40_RS03355	COG3121	Chaperone
HXP40_RS03375	COG3539	Fimbrial protein
HXP40_RS03380	COG2960	long-chain fatty acid transporting porin activity
HXP40_RS03400	COG3384	dioxygenase
HXP40_RS03405	COG0754	glutathionylspermidine amidase activity
HXP40_RS03415	COG1538	Outer membrane efflux protein
HXP40_RS03420	COG0494	nUDIX hydrolase
HXP40_RS03425	COG3151	Protein conserved in bacteria
HXP40_RS03430	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HXP40_RS03435	COG3150	esterase
HXP40_RS03440	COG0187	DNA topoisomerase II activity
HXP40_RS03445	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HXP40_RS03450	COG2249	NAD(P)H dehydrogenase (quinone) activity
HXP40_RS03460	COG0642	Histidine kinase
HXP40_RS03465	COG0745	RESPONSE REGULATOR receiver
HXP40_RS03470	COG3111	PFAM Bacterial OB fold (BOF) protein
HXP40_RS03475	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HXP40_RS03485	COG2944	sequence-specific DNA binding
HXP40_RS03490	COG4166	transmembrane transport
HXP40_RS03495	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HXP40_RS03500	COG0204	Acyl-transferase
HXP40_RS03505	COG2132	Multicopper oxidase
HXP40_RS03510	COG1032	radical SAM domain protein
HXP40_RS03515	COG4238	major outer membrane lipoprotein
HXP40_RS03525	COG0656	L-ascorbic acid biosynthetic process
HXP40_RS03530	COG1979	alcohol dehydrogenase
HXP40_RS03535	COG2207	Transcriptional regulator
HXP40_RS03540	COG0586	Pfam SNARE associated Golgi protein
HXP40_RS03545	COG0626	cystathionine gamma-synthase activity
HXP40_RS03550	COG0811	peptide transport
HXP40_RS03555	COG0848	biopolymer transport protein
HXP40_RS03560	COG1028	Short-chain dehydrogenase reductase Sdr
HXP40_RS03570	COG0667	Aldo Keto reductase
HXP40_RS03585	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HXP40_RS03590	COG0437	4 iron, 4 sulfur cluster binding
HXP40_RS03595	COG5557	Pfam Polysulphide reductase, NrfD
HXP40_RS03600	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HXP40_RS03605	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HXP40_RS03610	COG1773	rubredoxin
HXP40_RS03620	COG0298	carbon dioxide binding
HXP40_RS03625	COG0625	glutathione transferase activity
HXP40_RS03630	COG0754	glutathionylspermidine amidase activity
HXP40_RS03635	COG0306	phosphate transporter
HXP40_RS03640	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HXP40_RS03645	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HXP40_RS03650	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HXP40_RS03655	COG2244	polysaccharide biosynthetic process
HXP40_RS03665	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HXP40_RS03670	COG0795	lipopolysaccharide-transporting ATPase activity
HXP40_RS03680	COG0156	8-amino-7-oxononanoate synthase activity
HXP40_RS03685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HXP40_RS03695	COG0318	PFAM AMP-dependent synthetase and ligase
HXP40_RS03700	COG0456	acetyltransferase
HXP40_RS03705	COG2186	Transcriptional regulator
HXP40_RS03710	COG0277	FAD linked oxidase domain protein
HXP40_RS03715	COG0277	FAD linked oxidase domain protein
HXP40_RS03720	COG0247	lactate metabolic process
HXP40_RS03725	COG3193	protein, possibly involved in utilization of glycolate and propanediol
HXP40_RS03730	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HXP40_RS03735	COG1620	l-lactate permease
HXP40_RS03740	COG3064	Membrane
HXP40_RS03745	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HXP40_RS03755	COG3031	protein transport across the cell outer membrane
HXP40_RS03770	COG1459	type II secretion system
HXP40_RS03775	COG2165	general secretion pathway protein
HXP40_RS03805	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HXP40_RS03840	COG2003	Belongs to the UPF0758 family
HXP40_RS03865	COG2378	regulation of single-species biofilm formation
HXP40_RS03870	COG3596	GTP binding
HXP40_RS03890	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HXP40_RS03895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HXP40_RS03900	COG2313	pseudouridylate synthase activity
HXP40_RS03905	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HXP40_RS03910	COG1522	sequence-specific DNA binding
HXP40_RS03910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HXP40_RS03960	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HXP40_RS03965	COG2207	Transcriptional regulator
HXP40_RS03970	COG2972	Histidine kinase
HXP40_RS03990	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HXP40_RS03995	COG1882	Formate acetyltransferase
HXP40_RS04000	COG0693	protein deglycase activity
HXP40_RS04010	COG1012	belongs to the aldehyde dehydrogenase family
HXP40_RS04045	COG4820	ethanolamine utilization protein (EutJ)
HXP40_RS04050	COG4869	propanediol catabolic process
HXP40_RS04100	COG3969	phosphoadenosine phosphosulfate
HXP40_RS04105	COG1475	DNA binding
HXP40_RS04115	COG4584	PFAM Integrase catalytic
HXP40_RS04120	COG1484	DNA-dependent DNA replication
HXP40_RS04140	COG1201	RNA secondary structure unwinding
HXP40_RS04160	COG2194	sulfuric ester hydrolase activity
HXP40_RS04165	COG0582	viral genome integration into host DNA
HXP40_RS04175	COG1811	Na channel or pump
HXP40_RS04180	COG1982	Orn Lys Arg decarboxylase major
HXP40_RS04185	COG2211	Major facilitator Superfamily
HXP40_RS04200	COG1194	a g-specific adenine glycosylase
HXP40_RS04210	COG3171	Protein conserved in bacteria
HXP40_RS04220	COG0252	asparaginase activity
HXP40_RS04230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HXP40_RS04235	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HXP40_RS04245	COG0762	integral membrane protein
HXP40_RS04250	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HXP40_RS04255	COG2805	Type II/IV secretion system protein
HXP40_RS04270	COG0189	ligase activity
HXP40_RS04275	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HXP40_RS04280	COG2356	endonuclease I
HXP40_RS04290	COG2814	Major facilitator Superfamily
HXP40_RS04310	COG1166	arginine decarboxylase activity
HXP40_RS04320	COG0501	Belongs to the peptidase M48B family
HXP40_RS04325	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HXP40_RS04330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HXP40_RS04335	COG2213	PTS system mannitol-specific
HXP40_RS04340	COG1063	alcohol dehydrogenase
HXP40_RS04345	COG1494	fructose-1,6-bisphosphatase
HXP40_RS04350	COG3722	fumarate hydratase activity
HXP40_RS04355	COG1072	(Pantothenic acid kinase))
HXP40_RS04370	COG0191	fructose-bisphosphate aldolase activity
HXP40_RS04375	COG0668	transmembrane transport
HXP40_RS04380	COG1279	arginine transmembrane transporter activity
HXP40_RS04385	COG2968	Membrane
HXP40_RS04390	COG0583	DNA-binding transcription factor activity
HXP40_RS04395	COG0427	acetyl-CoA hydrolase
HXP40_RS04400	COG1024	Enoyl-CoA hydratase
HXP40_RS04405	COG1703	isobutyryl-CoA mutase activity
HXP40_RS04410	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HXP40_RS04410	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HXP40_RS04430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HXP40_RS04440	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HXP40_RS04460	COG0006	proline dipeptidase activity
HXP40_RS04465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HXP40_RS04470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HXP40_RS04495	COG1028	Short-chain dehydrogenase reductase Sdr
HXP40_RS04500	COG2723	6-phospho-beta-galactosidase activity
HXP40_RS04510	COG1272	protein, Hemolysin III
HXP40_RS04520	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HXP40_RS04530	COG0716	FMN binding
HXP40_RS04535	COG4974	Belongs to the 'phage' integrase family
HXP40_RS04540	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HXP40_RS04545	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HXP40_RS04555	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HXP40_RS04575	COG2233	PERMEase
HXP40_RS04580	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HXP40_RS04580	COG0493	'glutamate synthase
HXP40_RS04585	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HXP40_RS04590	COG2252	PERMEase
HXP40_RS04595	COG0402	S-adenosylhomocysteine deaminase activity
HXP40_RS04600	COG2233	PERMEase
HXP40_RS04605	COG2080	2 iron, 2 sulfur cluster binding
HXP40_RS04605	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HXP40_RS04610	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HXP40_RS04615	COG0402	S-adenosylhomocysteine deaminase activity
HXP40_RS04620	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HXP40_RS04620	COG0493	'glutamate synthase
HXP40_RS04625	COG2068	MobA-Related Protein
HXP40_RS04630	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HXP40_RS04635	COG3608	succinylglutamate desuccinylase aspartoacylase
HXP40_RS04635	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HXP40_RS04640	COG0549	Belongs to the carbamate kinase family
HXP40_RS04650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HXP40_RS04655	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HXP40_RS04660	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HXP40_RS04665	COG3829	transcription factor binding
HXP40_RS04670	COG2080	2 iron, 2 sulfur cluster binding
HXP40_RS04675	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HXP40_RS04680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HXP40_RS04685	COG4942	peptidase
HXP40_RS04695	COG4974	Belongs to the 'phage' integrase family
HXP40_RS04835	COG3710	Transcriptional regulator
HXP40_RS04835	COG0457	Tetratricopeptide repeat
HXP40_RS04840	COG0457	Tetratricopeptide repeat
HXP40_RS04865	COG3710	Transcriptional regulator
HXP40_RS04870	COG2771	luxR family
HXP40_RS04875	COG0814	amino acid
HXP40_RS04880	COG0183	Belongs to the thiolase family
HXP40_RS04890	COG1028	Short-chain dehydrogenase reductase Sdr
HXP40_RS04895	COG2814	Major facilitator Superfamily
HXP40_RS04900	COG1794	racemase activity, acting on amino acids and derivatives
HXP40_RS04905	COG0583	DNA-binding transcription factor activity
HXP40_RS04915	COG1609	Transcriptional regulator
HXP40_RS04930	COG0667	Aldo Keto reductase
HXP40_RS04940	COG0861	Integral membrane protein TerC family
HXP40_RS04955	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
HXP40_RS04970	COG2165	general secretion pathway protein
HXP40_RS04975	COG4795	General secretion pathway protein
HXP40_RS04985	COG4967	type IV pilus modification protein PilV
HXP40_RS04990	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HXP40_RS04995	COG1025	Belongs to the peptidase M16 family
HXP40_RS05000	COG1074	ATP-dependent DNA helicase activity
HXP40_RS05005	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HXP40_RS05010	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HXP40_RS05010	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HXP40_RS05015	COG0860	N-Acetylmuramoyl-L-alanine amidase
HXP40_RS05035	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HXP40_RS05040	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HXP40_RS05045	COG2166	iron-sulfur cluster assembly
HXP40_RS05050	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HXP40_RS05060	COG0583	DNA-binding transcription factor activity
HXP40_RS05065	COG2363	Small membrane protein
HXP40_RS05075	COG1349	DNA-binding transcription factor activity
HXP40_RS05085	COG1070	Carbohydrate kinase
HXP40_RS05095	COG0738	Major facilitator superfamily
HXP40_RS05100	COG0235	Class ii aldolase
HXP40_RS05105	COG1454	alcohol dehydrogenase
HXP40_RS05115	COG1760	l-serine dehydratase
HXP40_RS05120	COG0814	amino acid
HXP40_RS05125	COG1611	Belongs to the LOG family
HXP40_RS05140	COG3098	single-species biofilm formation
HXP40_RS05145	COG0564	pseudouridine synthase activity
HXP40_RS05150	COG0716	FMN binding
HXP40_RS05155	COG2271	Major facilitator Superfamily
HXP40_RS05160	COG4948	Mandelate Racemase Muconate Lactonizing
HXP40_RS05165	COG4948	Mandelate Racemase Muconate Lactonizing
HXP40_RS05170	COG3850	Histidine kinase
HXP40_RS05170	COG4999	Histidine kinase
HXP40_RS05170	COG3437	response regulator, receiver
HXP40_RS05170	COG2205	protein histidine kinase activity
HXP40_RS05175	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HXP40_RS05180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HXP40_RS05185	COG2336	PFAM SpoVT AbrB
HXP40_RS05190	COG2337	Toxic component of a toxin-antitoxin (TA) module
HXP40_RS05195	COG3956	TIGRFAM MazG family protein
HXP40_RS05210	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HXP40_RS05220	COG0602	queuosine metabolic process
HXP40_RS05225	COG1070	Carbohydrate kinase
HXP40_RS05230	COG2223	nitrite transmembrane transporter activity
HXP40_RS05235	COG1028	Short-chain dehydrogenase reductase Sdr
HXP40_RS05240	COG0277	FAD linked oxidase domain protein
HXP40_RS05245	COG0477	Major facilitator Superfamily
HXP40_RS05250	COG2086	electron transfer activity
HXP40_RS05255	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HXP40_RS05260	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HXP40_RS05265	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HXP40_RS05270	COG0644	oxidoreductase
HXP40_RS05275	COG0720	synthase
HXP40_RS05295	COG1203	CRISPR-associated helicase, Cas3
HXP40_RS05310	COG1857	crispr-associated protein
HXP40_RS05325	COG1518	maintenance of DNA repeat elements
HXP40_RS05330	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HXP40_RS05335	COG2234	aminopeptidase activity
HXP40_RS05390	COG1388	LysM domain
HXP40_RS05390	COG4942	peptidase
HXP40_RS05395	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HXP40_RS05400	COG2610	gluconate transmembrane transporter activity
HXP40_RS05405	COG3622	Belongs to the hyi family
HXP40_RS05410	COG0235	Class ii aldolase
HXP40_RS05415	COG3395	kinase activity
HXP40_RS05420	COG2084	Dehydrogenase
HXP40_RS05425	COG1349	DNA-binding transcription factor activity
HXP40_RS05430	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HXP40_RS05450	COG3604	Transcriptional regulator
HXP40_RS05455	COG0309	Hydrogenase expression formation protein (HypE)
HXP40_RS05460	COG0409	Hydrogenase expression formation protein
HXP40_RS05465	COG0298	carbon dioxide binding
HXP40_RS05470	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HXP40_RS05475	COG0375	protein maturation
HXP40_RS05485	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HXP40_RS05490	COG0651	ATP synthesis coupled electron transport
HXP40_RS05495	COG0650	Formate hydrogenlyase subunit 4
HXP40_RS05500	COG3261	NADH dehydrogenase
HXP40_RS05500	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HXP40_RS05505	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HXP40_RS05510	COG3260	NADH ubiquinone oxidoreductase 20
HXP40_RS05520	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HXP40_RS05525	COG2723	6-phospho-beta-galactosidase activity
HXP40_RS05530	COG1263	PTS System
HXP40_RS05530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HXP40_RS05535	COG1609	Transcriptional regulator
HXP40_RS05540	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HXP40_RS05545	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HXP40_RS05565	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HXP40_RS05565	COG0517	IMP dehydrogenase activity
HXP40_RS05570	COG1349	DNA-binding transcription factor activity
HXP40_RS05575	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HXP40_RS05580	COG1028	Short-chain dehydrogenase reductase Sdr
HXP40_RS05585	COG3731	PTS system glucitol sorbitol-specific IIA component
HXP40_RS05590	COG3732	PTS system glucitol sorbitol-specific
HXP40_RS05595	COG3730	PTS system glucitol sorbitol-specific
HXP40_RS05600	COG2951	lytic endotransglycosylase activity
HXP40_RS05605	COG1546	Belongs to the CinA family
HXP40_RS05625	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HXP40_RS05655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HXP40_RS05660	COG1238	metal cluster binding
HXP40_RS05675	COG2814	Major facilitator Superfamily
HXP40_RS05680	COG1566	PFAM secretion protein HlyD family protein
HXP40_RS05685	COG1846	Transcriptional regulator
HXP40_RS05695	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HXP40_RS05700	COG2814	Major facilitator Superfamily
HXP40_RS05705	COG2113	Glycine betaine
HXP40_RS05710	COG4176	ABC-type proline glycine betaine transport system permease component
HXP40_RS05715	COG4175	Glycine betaine
HXP40_RS05720	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HXP40_RS05725	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HXP40_RS05735	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HXP40_RS05740	COG4575	ribosome binding
HXP40_RS05755	COG2916	Histone family protein nucleoid-structuring protein H-NS
HXP40_RS05760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HXP40_RS05765	COG0640	Transcriptional regulator
HXP40_RS05770	COG0401	homolog of Blt101
HXP40_RS05775	COG1652	LysM domain
HXP40_RS05780	COG1802	Transcriptional regulator
HXP40_RS05785	COG1113	amino acid transport
HXP40_RS05790	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HXP40_RS05795	COG1012	belongs to the aldehyde dehydrogenase family
HXP40_RS05800	COG0579	oxidoreductase
HXP40_RS05835	COG3468	outer membrane autotransporter barrel domain protein
HXP40_RS05850	COG2867	negative regulation of translational initiation
HXP40_RS05860	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HXP40_RS05865	COG0497	DNA recombination
HXP40_RS05880	COG4536	flavin adenine dinucleotide binding
HXP40_RS05885	COG4137	Cytochrome C assembly protein
HXP40_RS05890	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HXP40_RS05915	COG2885	chlorophyll binding
HXP40_RS05920	COG2199	diguanylate cyclase activity
HXP40_RS05935	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HXP40_RS05940	COG1605	Chorismate mutase
HXP40_RS05940	COG0287	Prephenate dehydrogenase
HXP40_RS05945	COG0077	Prephenate dehydratase
HXP40_RS05945	COG1605	Chorismate mutase
HXP40_RS05955	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HXP40_RS05960	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HXP40_RS05965	COG0564	pseudouridine synthase activity
HXP40_RS05970	COG1496	oxidoreductase activity
HXP40_RS05975	COG0542	response to heat
HXP40_RS06000	COG0477	Major facilitator Superfamily
HXP40_RS06005	COG5544	Lipoprotein
HXP40_RS06010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HXP40_RS06015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HXP40_RS06015	COG1042	CoA-binding domain protein
HXP40_RS06015	COG0045	succinate-CoA ligase (ADP-forming) activity
HXP40_RS06020	COG3148	PFAM DTW domain containing protein
HXP40_RS06025	COG3118	belongs to the thioredoxin family
HXP40_RS06030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HXP40_RS06050	COG0583	DNA-binding transcription factor activity
HXP40_RS06055	COG0513	Belongs to the DEAD box helicase family
HXP40_RS06065	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HXP40_RS06075	COG1595	DNA-templated transcription, initiation
HXP40_RS06080	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HXP40_RS06085	COG3026	antisigma factor binding
HXP40_RS06090	COG3086	response to oxidative stress
HXP40_RS06100	COG0681	Belongs to the peptidase S26 family
HXP40_RS06120	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HXP40_RS06135	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HXP40_RS06140	COG1737	Transcriptional regulator
HXP40_RS06145	COG0560	Phosphoserine phosphatase
HXP40_RS06160	COG0047	phosphoribosylformylglycinamidine synthase activity
HXP40_RS06160	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HXP40_RS06165	COG2205	protein histidine kinase activity
HXP40_RS06170	COG3170	Tfp pilus assembly protein FimV
HXP40_RS06175	COG2204	response regulator
HXP40_RS06180	COG0347	Belongs to the P(II) protein family
HXP40_RS06185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HXP40_RS06185	COG1017	nitric oxide dioxygenase activity
HXP40_RS06195	COG1940	carbohydrate kinase activity
HXP40_RS06200	COG0457	Tetratricopeptide repeat
HXP40_RS06205	COG1879	ABC-type sugar transport system periplasmic component
HXP40_RS06210	COG1129	ABC transporter
HXP40_RS06215	COG1172	Belongs to the binding-protein-dependent transport system permease family
HXP40_RS06220	COG1063	alcohol dehydrogenase
HXP40_RS06225	COG2017	converts alpha-aldose to the beta-anomer
HXP40_RS06230	COG2259	Doxx family
HXP40_RS06255	COG4638	Rieske (2fe-2S)
HXP40_RS06260	COG0583	DNA-binding transcription factor activity
HXP40_RS06265	COG2814	Major facilitator Superfamily
HXP40_RS06270	COG3711	transcriptional antiterminator
HXP40_RS06275	COG1073	alpha beta
HXP40_RS06280	COG0483	inositol monophosphate 1-phosphatase activity
HXP40_RS06300	COG0822	iron-sulfur transferase activity
HXP40_RS06320	COG0633	Ferredoxin
HXP40_RS06325	COG2975	iron-sulfur cluster assembly
HXP40_RS06340	COG2897	thiosulfate sulfurtransferase activity
HXP40_RS06345	COG2373	Large extracellular alpha-helical protein
HXP40_RS06350	COG4953	penicillin-binding protein 1C
HXP40_RS06380	COG2976	Protein conserved in bacteria
HXP40_RS06395	COG1645	bacterial-type flagellum-dependent swarming motility
HXP40_RS06405	COG0517	IMP dehydrogenase activity
HXP40_RS06405	COG0516	GMP reductase activity
HXP40_RS06420	COG3133	Outer membrane lipoprotein
HXP40_RS06435	COG2200	EAL domain
HXP40_RS06440	COG0248	Ppx GppA phosphatase
HXP40_RS06445	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HXP40_RS06450	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HXP40_RS06465	COG2233	PERMEase
HXP40_RS06475	COG1393	Belongs to the ArsC family
HXP40_RS06480	COG4783	chaperone-mediated protein folding
HXP40_RS06485	COG0628	permease
HXP40_RS06490	COG2116	formate transmembrane transporter activity
HXP40_RS06495	COG3604	Transcriptional regulator
HXP40_RS06505	COG3260	NADH ubiquinone oxidoreductase 20
HXP40_RS06510	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HXP40_RS06515	COG3261	NADH dehydrogenase
HXP40_RS06515	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HXP40_RS06520	COG0651	ATP synthesis coupled electron transport
HXP40_RS06525	COG4237	Hydrogenase 4 membrane
HXP40_RS06530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HXP40_RS06535	COG0650	Formate hydrogenlyase subunit 4
HXP40_RS06540	COG0651	ATP synthesis coupled electron transport
HXP40_RS06545	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HXP40_RS06550	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HXP40_RS06555	COG2716	regulation of RNA biosynthetic process
HXP40_RS06565	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HXP40_RS06575	COG2321	neutral zinc metallopeptidase
HXP40_RS06580	COG1444	tRNA N-acetyltransferase activity
HXP40_RS06585	COG0400	carboxylic ester hydrolase activity
HXP40_RS06600	COG1393	Belongs to the ArsC family
HXP40_RS06610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HXP40_RS06615	COG3850	Histidine kinase
HXP40_RS06620	COG0493	'glutamate synthase
HXP40_RS06620	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HXP40_RS06630	COG5342	invasion associated locus B
HXP40_RS06635	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HXP40_RS06640	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HXP40_RS06645	COG0281	malic enzyme
HXP40_RS06645	COG0280	phosphate acetyltransferase
HXP40_RS06650	COG4810	utilization protein
HXP40_RS06655	COG4917	ethanolamine utilization protein
HXP40_RS06660	COG4766	ethanolamine catabolic process
HXP40_RS06665	COG4812	Cobalamin adenosyltransferase
HXP40_RS06670	COG0280	phosphate acetyltransferase
HXP40_RS06675	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HXP40_RS06680	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
HXP40_RS06685	COG1012	belongs to the aldehyde dehydrogenase family
HXP40_RS06690	COG4820	ethanolamine utilization protein (EutJ)
HXP40_RS06695	COG1454	alcohol dehydrogenase
HXP40_RS06700	COG3192	ethanolamine utilization protein
HXP40_RS06705	COG4819	ethanolamine utilization protein
HXP40_RS06710	COG4303	Ethanolamine ammonia lyase large subunit
HXP40_RS06720	COG4816	utilization protein
HXP40_RS06725	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HXP40_RS06730	COG2207	Transcriptional regulator
HXP40_RS06740	COG0860	N-Acetylmuramoyl-L-alanine amidase
HXP40_RS06745	COG0456	acetyltransferase
HXP40_RS06760	COG2837	iron assimilation
HXP40_RS06765	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HXP40_RS06770	COG1263	PTS System
HXP40_RS06770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HXP40_RS06785	COG1028	Short-chain dehydrogenase reductase Sdr
HXP40_RS06790	COG4150	thiosulfate binding
HXP40_RS06795	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HXP40_RS06800	COG4208	sulfate ABC transporter
HXP40_RS06805	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HXP40_RS06810	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HXP40_RS06815	COG3831	ATPase activity
HXP40_RS06815	COG4884	unkown
HXP40_RS06830	COG2190	(PTS) system
HXP40_RS06835	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HXP40_RS06840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HXP40_RS06845	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HXP40_RS06865	COG3530	Putative quorum-sensing-regulated virulence factor
HXP40_RS06870	COG0385	Bile acid
HXP40_RS06875	COG0583	DNA-binding transcription factor activity
HXP40_RS06885	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HXP40_RS06890	COG2211	Major facilitator Superfamily
HXP40_RS06900	COG0583	DNA-binding transcription factor activity
HXP40_RS06930	COG3415	Transposase
HXP40_RS06935	COG3415	Transposase
HXP40_RS06950	COG2200	EAL domain
HXP40_RS06950	COG2199	diguanylate cyclase activity
HXP40_RS06955	COG3385	transposase activity
HXP40_RS06960	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HXP40_RS06985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HXP40_RS06990	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HXP40_RS06995	COG0006	proline dipeptidase activity
HXP40_RS07000	COG1363	Peptidase, m42
HXP40_RS07005	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HXP40_RS07005	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HXP40_RS07005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HXP40_RS07015	COG3279	Response regulator of the LytR AlgR family
HXP40_RS07020	COG3275	phosphorelay sensor kinase activity
HXP40_RS07025	COG0436	Aminotransferase
HXP40_RS07035	COG1560	Kdo2-lipid A biosynthetic process
HXP40_RS07060	COG0028	Belongs to the TPP enzyme family
HXP40_RS07065	COG0679	Auxin Efflux Carrier
HXP40_RS07070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HXP40_RS07075	COG0784	Response regulator, receiver
HXP40_RS07075	COG2205	protein histidine kinase activity
HXP40_RS07075	COG2198	Histidine kinase
HXP40_RS07075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HXP40_RS07080	COG2197	response regulator
HXP40_RS07085	COG1566	PFAM secretion protein HlyD family protein
HXP40_RS07090	COG0477	Major facilitator Superfamily
HXP40_RS07130	COG2116	formate transmembrane transporter activity
HXP40_RS07135	COG2853	Lipoprotein
HXP40_RS07145	COG3547	Transposase (IS116 IS110 IS902 family)
HXP40_RS07150	COG2067	long-chain fatty acid transport protein
HXP40_RS07155	COG3691	Protein conserved in bacteria
HXP40_RS07170	COG2062	phosphohistidine phosphatase, SixA
HXP40_RS07175	COG3539	Fimbrial protein
HXP40_RS07180	COG3188	usher protein
HXP40_RS07185	COG3121	Chaperone
HXP40_RS07190	COG3539	Fimbrial protein
HXP40_RS07195	COG3539	Fimbrial protein
HXP40_RS07200	COG3539	Fimbrial protein
HXP40_RS07215	COG2890	protein-(glutamine-N5) methyltransferase activity
HXP40_RS07230	COG0730	response to heat
HXP40_RS07235	COG3101	peptidyl-lysine hydroxylation
HXP40_RS07250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HXP40_RS07255	COG2814	Major facilitator Superfamily
HXP40_RS07270	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HXP40_RS07280	COG0586	Pfam SNARE associated Golgi protein
HXP40_RS07290	COG0285	dihydrofolate synthase activity
HXP40_RS07295	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HXP40_RS07300	COG1286	toxin biosynthetic process
HXP40_RS07305	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HXP40_RS07310	COG0163	prenyltransferase activity
HXP40_RS07315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HXP40_RS07320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HXP40_RS07325	COG4215	(ABC) transporter
HXP40_RS07330	COG4160	amino acid transport
HXP40_RS07335	COG4598	ABC transporter
HXP40_RS07340	COG5464	transposase or invertase
HXP40_RS07345	COG1090	epimerase
HXP40_RS07350	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HXP40_RS07355	COG0625	glutathione transferase activity
HXP40_RS07360	COG0625	glutathione transferase activity
HXP40_RS07365	COG0622	Phosphoesterase
HXP40_RS07370	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HXP40_RS07375	COG1288	antiporter activity
HXP40_RS07380	COG0857	belongs to the CobB CobQ family
HXP40_RS07380	COG0280	phosphate acetyltransferase
HXP40_RS07385	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HXP40_RS07400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HXP40_RS07405	COG0471	metal ion transport
HXP40_RS07405	COG0490	domain, Protein
HXP40_RS07415	COG0436	Aminotransferase
HXP40_RS07420	COG0583	DNA-binding transcription factor activity
HXP40_RS07440	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HXP40_RS07445	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HXP40_RS07450	COG1034	ATP synthesis coupled electron transport
HXP40_RS07465	COG0839	Belongs to the complex I subunit 6 family
HXP40_RS07475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HXP40_RS07480	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HXP40_RS07490	COG0457	Tetratricopeptide repeat
HXP40_RS07510	COG2234	aminopeptidase activity
HXP40_RS07515	COG2304	oxidoreductase activity
HXP40_RS07530	COG2153	protein acetylation
HXP40_RS07535	COG4575	ribosome binding
HXP40_RS07540	COG1169	isochorismate synthase
HXP40_RS07555	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HXP40_RS07565	COG0318	PFAM AMP-dependent synthetase and ligase
HXP40_RS07640	COG2271	Major facilitator Superfamily
HXP40_RS07655	COG5464	transposase or invertase
HXP40_RS07660	COG0247	lactate metabolic process
HXP40_RS07670	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HXP40_RS07675	COG2271	Major facilitator Superfamily
HXP40_RS07680	COG0584	glycerophosphoryl diester phosphodiesterase
HXP40_RS07690	COG3642	lipopolysaccharide core region biosynthetic process
HXP40_RS07695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HXP40_RS07700	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HXP40_RS07705	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HXP40_RS07710	COG3468	outer membrane autotransporter barrel domain protein
HXP40_RS07720	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HXP40_RS07725	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
HXP40_RS07730	COG3234	Protein of unknown function (DUF1175)
HXP40_RS07735	COG2373	Large extracellular alpha-helical protein
HXP40_RS07740	COG5445	Predicted secreted protein (DUF2300)
HXP40_RS07745	COG4676	Protein conserved in bacteria
HXP40_RS07750	COG0183	Belongs to the thiolase family
HXP40_RS07755	COG2031	fatty acid transporter
HXP40_RS07760	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HXP40_RS07765	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HXP40_RS07770	COG2204	response regulator
HXP40_RS07775	COG3852	Histidine kinase
HXP40_RS07780	COG0784	Response regulator, receiver
HXP40_RS07780	COG2205	protein histidine kinase activity
HXP40_RS07785	COG2197	response regulator
HXP40_RS07790	COG0642	Histidine kinase
HXP40_RS07790	COG2198	Histidine kinase
HXP40_RS07795	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HXP40_RS07800	COG1477	protein flavinylation
HXP40_RS07805	COG2169	Transcriptional regulator
HXP40_RS07805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HXP40_RS07810	COG3145	DNA-N1-methyladenine dioxygenase activity
HXP40_RS07815	COG4615	Cyclic peptide transporter
HXP40_RS07830	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HXP40_RS07830	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HXP40_RS07835	COG3062	negative regulation of establishment of protein localization
HXP40_RS07845	COG0437	4 iron, 4 sulfur cluster binding
HXP40_RS07850	COG0348	domain, Protein
HXP40_RS07855	COG3043	anaerobic respiration
HXP40_RS07860	COG3005	denitrification pathway
HXP40_RS07865	COG4133	protoheme IX ABC transporter activity
HXP40_RS07870	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HXP40_RS07875	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HXP40_RS07880	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HXP40_RS07890	COG1138	Cytochrome C-type biogenesis protein
HXP40_RS07895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HXP40_RS07900	COG4235	cytochrome complex assembly
HXP40_RS07900	COG3088	subunit of a heme lyase
HXP40_RS07905	COG2197	response regulator
HXP40_RS07910	COG3468	outer membrane autotransporter barrel domain protein
HXP40_RS07920	COG3083	sulfuric ester hydrolase activity
HXP40_RS07940	COG1061	Type III restriction enzyme res subunit
HXP40_RS07945	COG1187	pseudouridine synthase activity
HXP40_RS07950	COG2814	Major facilitator Superfamily
HXP40_RS07960	COG4172	Belongs to the ABC transporter superfamily
HXP40_RS07965	COG4239	(ABC) transporter, permease
HXP40_RS07970	COG4174	ABC transporter (Permease)
HXP40_RS07975	COG4166	transmembrane transport
HXP40_RS07980	COG2200	EAL domain
HXP40_RS07985	COG0791	NLP P60 protein
HXP40_RS07990	COG0671	phosphoesterase, PA-phosphatase related
HXP40_RS07995	COG0523	cobalamin synthesis protein
HXP40_RS08000	COG0246	Mannitol dehydrogenase
HXP40_RS08015	COG2814	Major facilitator Superfamily
HXP40_RS08020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HXP40_RS08020	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HXP40_RS08025	COG1105	Belongs to the carbohydrate kinase PfkB family
HXP40_RS08030	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HXP40_RS08030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HXP40_RS08030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HXP40_RS08035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HXP40_RS08040	COG2313	pseudouridylate synthase activity
HXP40_RS08045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HXP40_RS08050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HXP40_RS08060	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HXP40_RS08065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HXP40_RS08065	COG1522	sequence-specific DNA binding
HXP40_RS08075	COG2855	membrane
HXP40_RS08080	COG0583	DNA-binding transcription factor activity
HXP40_RS08085	COG0833	amino acid
HXP40_RS08105	COG2311	Membrane
HXP40_RS08110	COG1609	Transcriptional regulator
HXP40_RS08115	COG1879	ABC-type sugar transport system periplasmic component
HXP40_RS08120	COG1129	ABC transporter
HXP40_RS08125	COG4211	Belongs to the binding-protein-dependent transport system permease family
HXP40_RS08130	COG0167	dihydroorotate dehydrogenase activity
HXP40_RS08130	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HXP40_RS08135	COG0493	'glutamate synthase
HXP40_RS08145	COG2949	membrane
HXP40_RS08155	COG1346	cytolysis
HXP40_RS08165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HXP40_RS08180	COG1028	Short-chain dehydrogenase reductase Sdr
HXP40_RS08185	COG0586	Pfam SNARE associated Golgi protein
HXP40_RS08195	COG1686	Belongs to the peptidase S11 family
HXP40_RS08200	COG0277	FAD linked oxidase domain protein
HXP40_RS08205	COG1472	Belongs to the glycosyl hydrolase 3 family
HXP40_RS08210	COG1732	Glycine betaine
HXP40_RS08215	COG1174	glycine betaine transport
HXP40_RS08220	COG1125	glycine betaine transport
HXP40_RS08225	COG1174	glycine betaine transport
HXP40_RS08235	COG0789	Transcriptional regulator
HXP40_RS08240	COG3275	phosphorelay sensor kinase activity
HXP40_RS08245	COG3279	Response regulator of the LytR AlgR family
HXP40_RS08250	COG4807	Protein conserved in bacteria
HXP40_RS08255	COG4808	Protein conserved in bacteria
HXP40_RS08260	COG4715	Zinc finger, swim domain protein
HXP40_RS08265	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HXP40_RS08285	COG3831	ATPase activity
HXP40_RS08290	COG3831	ATPase activity
HXP40_RS08295	COG3831	ATPase activity
HXP40_RS08305	COG0489	protein tyrosine kinase activity
HXP40_RS08315	COG3539	Fimbrial protein
HXP40_RS08320	COG3121	Chaperone
HXP40_RS08325	COG3188	usher protein
HXP40_RS08330	COG3539	Fimbrial protein
HXP40_RS08335	COG5455	response to cobalt ion
HXP40_RS08355	COG0351	phosphomethylpyrimidine kinase
HXP40_RS08360	COG3757	hydrolase, family 25
HXP40_RS08365	COG2188	Transcriptional regulator
HXP40_RS08370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HXP40_RS08375	COG1397	ADP-ribosylglycohydrolase
HXP40_RS08380	COG2211	Major facilitator Superfamily
HXP40_RS08385	COG1830	Aldolase
HXP40_RS08400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HXP40_RS08405	COG3414	Phosphotransferase system galactitol-specific IIB component
HXP40_RS08410	COG3775	system Galactitol-specific IIC component
HXP40_RS08415	COG1063	alcohol dehydrogenase
HXP40_RS08435	COG0826	peptidase U32
HXP40_RS08445	COG3609	addiction module antidote protein, CC2985 family
HXP40_RS08455	COG0745	RESPONSE REGULATOR receiver
HXP40_RS08460	COG2205	protein histidine kinase activity
HXP40_RS08500	COG4245	von Willebrand factor, type A
HXP40_RS08505	COG0631	protein serine/threonine phosphatase activity
HXP40_RS08515	COG0443	Heat shock 70 kDa protein
HXP40_RS08520	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HXP40_RS08525	COG5001	Diguanylate cyclase
HXP40_RS08525	COG3447	MASE1 domain protein
HXP40_RS08525	COG5002	protein histidine kinase activity
HXP40_RS08530	COG0572	uridine kinase
HXP40_RS08540	COG2982	Protein involved in outer membrane biogenesis
HXP40_RS08555	COG1253	flavin adenine dinucleotide binding
HXP40_RS08625	COG0438	transferase activity, transferring glycosyl groups
HXP40_RS08640	COG0110	maltose O-acetyltransferase activity
HXP40_RS08650	COG1088	dTDP-glucose 4,6-dehydratase activity
HXP40_RS08695	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HXP40_RS08705	COG0438	transferase activity, transferring glycosyl groups
HXP40_RS08715	COG0140	phosphoribosyl-ATP diphosphatase activity
HXP40_RS08715	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HXP40_RS08730	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HXP40_RS08735	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HXP40_RS08735	COG0131	Imidazoleglycerol-phosphate dehydratase
HXP40_RS08760	COG2161	toxin-antitoxin pair type II binding
HXP40_RS08765	COG4115	mRNA cleavage
HXP40_RS08770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HXP40_RS08775	COG0583	DNA-binding transcription factor activity
HXP40_RS08785	COG0531	amino acid
HXP40_RS08790	COG2391	methyltransferase activity
HXP40_RS08795	COG0425	Belongs to the sulfur carrier protein TusA family
HXP40_RS08800	COG2925	Exonuclease
HXP40_RS08805	COG1686	Belongs to the peptidase S11 family
HXP40_RS08815	COG1289	transmembrane transporter activity
HXP40_RS08825	COG4917	ethanolamine utilization protein
HXP40_RS08865	COG1484	DNA-dependent DNA replication
HXP40_RS08870	COG4584	PFAM Integrase catalytic
HXP40_RS08875	COG2003	Belongs to the UPF0758 family
HXP40_RS08895	COG3468	outer membrane autotransporter barrel domain protein
HXP40_RS08955	COG1735	metal-dependent hydrolase with the TIM-barrel fold
HXP40_RS08970	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
HXP40_RS08985	COG1376	ErfK ybiS ycfS ynhG family protein
HXP40_RS08995	COG0583	DNA-binding transcription factor activity
HXP40_RS09000	COG0583	DNA-binding transcription factor activity
HXP40_RS09010	COG0534	Mate efflux family protein
HXP40_RS09020	COG0217	transcriptional regulatory protein
HXP40_RS09025	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HXP40_RS09030	COG0477	Major facilitator Superfamily
HXP40_RS09050	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HXP40_RS09115	COG3504	Conjugal transfer protein
HXP40_RS09195	COG4771	TonB-dependent receptor
HXP40_RS09200	COG1021	2,3-dihydroxybenzoate-AMP ligase
HXP40_RS09220	COG2226	methyltransferase
HXP40_RS09220	COG3433	isochorismatase activity
HXP40_RS09220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HXP40_RS09235	COG1132	(ABC) transporter
HXP40_RS09240	COG2814	Major facilitator Superfamily
HXP40_RS09245	COG1169	isochorismate synthase
HXP40_RS09250	COG0582	viral genome integration into host DNA
HXP40_RS09275	COG3443	Belongs to the bacterial solute-binding protein 9 family
HXP40_RS09290	COG2351	hydroxyisourate hydrolase activity
HXP40_RS09295	COG0745	RESPONSE REGULATOR receiver
HXP40_RS09300	COG2205	protein histidine kinase activity
HXP40_RS09315	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HXP40_RS09325	COG1418	mRNA catabolic process
HXP40_RS09330	COG0270	DNA (cytosine-5-)-methyltransferase activity
HXP40_RS09335	COG3727	T/G mismatch-specific endonuclease activity
HXP40_RS09340	COG0697	spore germination
HXP40_RS09345	COG2354	Protein conserved in bacteria
HXP40_RS09350	COG5475	Uncharacterized small protein (DUF2158)
HXP40_RS09375	COG2197	response regulator
HXP40_RS09380	COG1684	flagellar biosynthetic protein fliR
HXP40_RS09385	COG1987	bacterial-type flagellum assembly
HXP40_RS09390	COG1338	Plays a role in the flagellum-specific transport system
HXP40_RS09395	COG3190	flagellar
HXP40_RS09400	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HXP40_RS09405	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HXP40_RS09410	COG1580	Controls the rotational direction of flagella during chemotaxis
HXP40_RS09415	COG3144	bacterial-type flagellum assembly
HXP40_RS09420	COG2882	bacterial-type flagellum organization
HXP40_RS09430	COG1317	bacterial-type flagellum organization
HXP40_RS09435	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HXP40_RS09440	COG1766	The M ring may be actively involved in energy transduction
HXP40_RS09460	COG2135	peptidase activity
HXP40_RS09465	COG0425	Belongs to the sulfur carrier protein TusA family
HXP40_RS09470	COG2391	methyltransferase activity
HXP40_RS09480	COG0366	Alpha amylase catalytic
HXP40_RS09490	COG1516	flagellar protein fliS
HXP40_RS09495	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HXP40_RS09505	COG1191	sigma factor activity
HXP40_RS09515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HXP40_RS09525	COG0765	amino acid transport
HXP40_RS09530	COG1126	abc transporter atp-binding protein
HXP40_RS09535	COG2197	response regulator
HXP40_RS09550	COG2197	response regulator
HXP40_RS09580	COG3318	Belongs to the UPF0149 family
HXP40_RS09580	COG3012	SEC-C Motif Domain Protein
HXP40_RS09585	COG0814	amino acid
HXP40_RS09595	COG1528	Iron-storage protein
HXP40_RS09615	COG1528	Iron-storage protein
HXP40_RS09620	COG1879	ABC-type sugar transport system periplasmic component
HXP40_RS09625	COG1129	ABC transporter
HXP40_RS09630	COG1172	Belongs to the binding-protein-dependent transport system permease family
HXP40_RS09635	COG1877	trehalose-phosphatase activity
HXP40_RS09645	COG0589	response to stress
HXP40_RS09660	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HXP40_RS09665	COG1360	Flagellar Motor Protein
HXP40_RS09670	COG0643	Histidine kinase
HXP40_RS09670	COG2198	Histidine kinase
HXP40_RS09675	COG0835	chemotaxis
HXP40_RS09680	COG0840	transmembrane signaling receptor activity
HXP40_RS09685	COG0840	transmembrane signaling receptor activity
HXP40_RS09690	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HXP40_RS09695	COG2201	protein-glutamate methylesterase activity
HXP40_RS09700	COG0745	RESPONSE REGULATOR receiver
HXP40_RS09705	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HXP40_RS09710	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HXP40_RS09725	COG3755	Protein conserved in bacteria
HXP40_RS09735	COG3102	Protein conserved in bacteria
HXP40_RS09745	COG3005	denitrification pathway
HXP40_RS09750	COG0243	molybdopterin cofactor binding
HXP40_RS09765	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HXP40_RS09770	COG1801	Protein of unknown function DUF72
HXP40_RS09775	COG1335	isochorismatase
HXP40_RS09785	COG0494	nUDIX hydrolase
HXP40_RS09790	COG0217	transcriptional regulatory protein
HXP40_RS09820	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HXP40_RS09830	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HXP40_RS09835	COG0739	heme binding
HXP40_RS09840	COG1560	Kdo2-lipid A biosynthetic process
HXP40_RS09845	COG0469	pyruvate kinase activity
HXP40_RS09850	COG1737	Transcriptional regulator
HXP40_RS09855	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HXP40_RS09860	COG0129	dihydroxy-acid dehydratase activity
HXP40_RS09865	COG0800	Aldolase
HXP40_RS09875	COG3141	response to X-ray
HXP40_RS09885	COG2979	Protein of unknown function (DUF533)
HXP40_RS09890	COG1770	oligopeptidase
HXP40_RS09895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HXP40_RS09900	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HXP40_RS09910	COG2372	response to copper ion
HXP40_RS09915	COG1276	copper resistance
HXP40_RS09925	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HXP40_RS09945	COG3008	intermembrane lipid transfer
HXP40_RS09950	COG2995	paraquat-inducible protein a
HXP40_RS09955	COG1956	GAF domain-containing protein
HXP40_RS09965	COG0793	Belongs to the peptidase S41A family
HXP40_RS09975	COG2814	Major facilitator Superfamily
HXP40_RS09980	COG1414	Transcriptional regulator
HXP40_RS10010	COG2226	methyltransferase
HXP40_RS10025	COG3716	PTS system mannose fructose sorbose family IID component
HXP40_RS10030	COG3715	PTS system
HXP40_RS10035	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HXP40_RS10035	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HXP40_RS10040	COG1253	flavin adenine dinucleotide binding
HXP40_RS10050	COG1760	l-serine dehydratase
HXP40_RS10060	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HXP40_RS10075	COG0251	oxidation-reduction process
HXP40_RS10080	COG1199	ATP-dependent helicase activity
HXP40_RS10085	COG1214	PFAM Peptidase M22, glycoprotease
HXP40_RS10090	COG3065	identical protein binding
HXP40_RS10095	COG0318	PFAM AMP-dependent synthetase and ligase
HXP40_RS10100	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HXP40_RS10105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HXP40_RS10110	COG4638	Rieske (2fe-2S)
HXP40_RS10120	COG0473	3-isopropylmalate dehydrogenase activity
HXP40_RS10125	COG0583	DNA-binding transcription factor activity
HXP40_RS10135	COG3615	Tellurite resistance protein tehB
HXP40_RS10145	COG2261	transglycosylase associated protein
HXP40_RS10160	COG2199	diguanylate cyclase activity
HXP40_RS10160	COG2203	Gaf domain
HXP40_RS10165	COG3042	response to heat
HXP40_RS10170	COG3189	MarR family transcriptional regulator
HXP40_RS10175	COG2807	transmembrane transport
HXP40_RS10180	COG2207	Transcriptional regulator
HXP40_RS10195	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HXP40_RS10200	COG2199	diguanylate cyclase activity
HXP40_RS10205	COG2199	diguanylate cyclase activity
HXP40_RS10215	COG2766	serine protein kinase
HXP40_RS10220	COG3713	MltA-interacting MipA family protein
HXP40_RS10225	COG0656	L-ascorbic acid biosynthetic process
HXP40_RS10230	COG0676	glucose-6-phosphate 1-epimerase activity
HXP40_RS10235	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HXP40_RS10245	COG3139	Protein of unknown function (DUF1315)
HXP40_RS10250	COG1063	alcohol dehydrogenase
HXP40_RS10255	COG2271	Major facilitator Superfamily
HXP40_RS10260	COG1063	alcohol dehydrogenase
HXP40_RS10265	COG0191	fructose-bisphosphate aldolase activity
HXP40_RS10270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HXP40_RS10275	COG0667	Aldo Keto reductase
HXP40_RS10280	COG1349	DNA-binding transcription factor activity
HXP40_RS10285	COG2814	Major facilitator Superfamily
HXP40_RS10290	COG1335	isochorismatase
HXP40_RS10295	COG0252	asparaginase activity
HXP40_RS10300	COG0616	signal peptide processing
HXP40_RS10305	COG0778	Nitroreductase
HXP40_RS10315	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HXP40_RS10325	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HXP40_RS10335	COG0494	nUDIX hydrolase
HXP40_RS10340	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HXP40_RS10345	COG2897	thiosulfate sulfurtransferase activity
HXP40_RS10350	COG4136	ATPase activity
HXP40_RS10355	COG4135	transport system, permease component
HXP40_RS10360	COG4134	Bacterial extracellular solute-binding protein
HXP40_RS10365	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HXP40_RS10370	COG0398	Pfam SNARE associated Golgi protein
HXP40_RS10380	COG0398	Pfam SNARE associated Golgi protein
HXP40_RS10385	COG0708	Exodeoxyribonuclease III
HXP40_RS10415	COG3678	ATP-independent chaperone mediated protein folding
HXP40_RS10425	COG0322	excinuclease ABC activity
HXP40_RS10435	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HXP40_RS10440	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HXP40_RS10445	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HXP40_RS10450	COG1447	Phosphotransferase system cellobiose-specific component IIA
HXP40_RS10455	COG2169	Transcriptional regulator
HXP40_RS10455	COG1917	Cupin 2, conserved barrel domain protein
HXP40_RS10460	COG1486	melibiose metabolic process
HXP40_RS10470	COG0753	catalase activity
HXP40_RS10485	COG1823	symporter activity
HXP40_RS10490	COG1988	membrane-bound metal-dependent
HXP40_RS10495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HXP40_RS10505	COG3001	Fructosamine kinase
HXP40_RS10515	COG1105	Belongs to the carbohydrate kinase PfkB family
HXP40_RS10520	COG3137	Salt-induced outer membrane protein
HXP40_RS10565	COG0072	phenylalanine-tRNA ligase activity
HXP40_RS10565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HXP40_RS10580	COG0386	Belongs to the glutathione peroxidase family
HXP40_RS10590	COG0791	NLP P60 protein
HXP40_RS10595	COG2200	EAL domain
HXP40_RS10605	COG4256	Hemin uptake protein
HXP40_RS10610	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HXP40_RS10620	COG0574	Belongs to the PEP-utilizing enzyme family
HXP40_RS10620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HXP40_RS10625	COG0318	PFAM AMP-dependent synthetase and ligase
HXP40_RS10630	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HXP40_RS10635	COG0644	oxidoreductase
HXP40_RS10640	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HXP40_RS10645	COG2086	electron transfer activity
HXP40_RS10650	COG2207	Transcriptional regulator
HXP40_RS10650	COG1917	Cupin 2, conserved barrel domain protein
HXP40_RS10655	COG1960	acyl-CoA dehydrogenase activity
HXP40_RS10660	COG4670	ketone body catabolic process
HXP40_RS10675	COG2271	Major facilitator Superfamily
HXP40_RS10680	COG0738	Major facilitator superfamily
HXP40_RS10695	COG0628	permease
HXP40_RS10700	COG0277	FAD linked oxidase domain protein
HXP40_RS10700	COG0247	lactate metabolic process
HXP40_RS10705	COG2050	protein possibly involved in aromatic compounds catabolism
HXP40_RS10715	COG0316	Belongs to the HesB IscA family
HXP40_RS10720	COG0719	Fe-S assembly protein
HXP40_RS10725	COG0396	ATPase activity
HXP40_RS10730	COG0719	Fe-S assembly protein
HXP40_RS10745	COG1376	ErfK ybiS ycfS ynhG family protein
HXP40_RS10750	COG4238	major outer membrane lipoprotein
HXP40_RS10755	COG0469	pyruvate kinase activity
HXP40_RS10765	COG0437	4 iron, 4 sulfur cluster binding
HXP40_RS10770	COG2414	aldehyde ferredoxin oxidoreductase
HXP40_RS10780	COG0437	4 iron, 4 sulfur cluster binding
HXP40_RS10785	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HXP40_RS10795	COG4529	Protein conserved in bacteria
HXP40_RS10815	COG3468	outer membrane autotransporter barrel domain protein
HXP40_RS10825	COG0307	riboflavin synthase, alpha
HXP40_RS10830	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HXP40_RS10835	COG2814	Major facilitator Superfamily
HXP40_RS10840	COG0583	DNA-binding transcription factor activity
HXP40_RS10855	COG2814	Major facilitator Superfamily
HXP40_RS10860	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HXP40_RS10865	COG0791	NLP P60 protein
HXP40_RS10870	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HXP40_RS10875	COG1201	RNA secondary structure unwinding
HXP40_RS10880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HXP40_RS10885	COG0346	lactoylglutathione lyase activity
HXP40_RS10890	COG1902	pentaerythritol trinitrate reductase activity
HXP40_RS10895	COG1309	transcriptional regulator
HXP40_RS10900	COG3313	Fe-S protein
HXP40_RS10905	COG4989	oxidoreductase activity
HXP40_RS10910	COG2032	superoxide dismutase activity
HXP40_RS10915	COG1289	transmembrane transporter activity
HXP40_RS10920	COG1566	PFAM secretion protein HlyD family protein
HXP40_RS10935	COG3133	Outer membrane lipoprotein
HXP40_RS10945	COG3895	Periplasmic Protein
HXP40_RS10960	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HXP40_RS10965	COG0625	glutathione transferase activity
HXP40_RS10970	COG3104	oligopeptide transport
HXP40_RS10975	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HXP40_RS10985	COG4659	FMN binding
HXP40_RS11025	COG0673	inositol 2-dehydrogenase activity
HXP40_RS11035	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HXP40_RS11040	COG1263	PTS System
HXP40_RS11040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HXP40_RS11045	COG1609	Transcriptional regulator
HXP40_RS11050	COG1028	Short-chain dehydrogenase reductase Sdr
HXP40_RS11055	COG1309	transcriptional regulator
HXP40_RS11060	COG3250	beta-galactosidase activity
HXP40_RS11075	COG5339	Protein conserved in bacteria
HXP40_RS11080	COG1482	cell wall glycoprotein biosynthetic process
HXP40_RS11085	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HXP40_RS11085	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HXP40_RS11090	COG0114	fumarate hydratase activity
HXP40_RS11100	COG2205	protein histidine kinase activity
HXP40_RS11105	COG0745	RESPONSE REGULATOR receiver
HXP40_RS11110	COG3136	membrane protein required for alginate biosynthesis
HXP40_RS11120	COG0531	amino acid
HXP40_RS11130	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HXP40_RS11135	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HXP40_RS11140	COG0628	permease
HXP40_RS11155	COG3591	Belongs to the peptidase S1B family
HXP40_RS11170	COG2814	Major facilitator Superfamily
HXP40_RS11175	COG0583	DNA-binding transcription factor activity
HXP40_RS11180	COG1940	carbohydrate kinase activity
HXP40_RS11185	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HXP40_RS11195	COG3381	protein complex oligomerization
HXP40_RS11200	COG3302	dmso reductase anchor subunit
HXP40_RS11205	COG0437	4 iron, 4 sulfur cluster binding
HXP40_RS11210	COG0243	molybdopterin cofactor binding
HXP40_RS11215	COG0243	molybdopterin cofactor binding
HXP40_RS11245	COG4584	PFAM Integrase catalytic
HXP40_RS11250	COG1484	DNA-dependent DNA replication
HXP40_RS11275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HXP40_RS11290	COG4948	Mandelate Racemase Muconate Lactonizing
HXP40_RS11295	COG1063	alcohol dehydrogenase
HXP40_RS11300	COG0477	Major facilitator Superfamily
HXP40_RS11305	COG0246	Mannitol dehydrogenase
HXP40_RS11315	COG1802	Transcriptional regulator
HXP40_RS11320	COG4221	oxidoreductase activity
HXP40_RS11325	COG0339	signal peptide processing
HXP40_RS11330	COG1546	Belongs to the CinA family
HXP40_RS11335	COG3111	PFAM Bacterial OB fold (BOF) protein
HXP40_RS11340	COG3706	GGDEF domain
HXP40_RS11350	COG2814	Major facilitator Superfamily
HXP40_RS11365	COG4977	sequence-specific DNA binding
HXP40_RS11370	COG1846	Transcriptional regulator
HXP40_RS11390	COG0583	DNA-binding transcription factor activity
HXP40_RS11395	COG1012	belongs to the aldehyde dehydrogenase family
HXP40_RS11400	COG2066	Belongs to the glutaminase family
HXP40_RS11420	COG3781	membrane
HXP40_RS11470	COG3210	domain, Protein
HXP40_RS11470	COG2911	Protein conserved in bacteria
HXP40_RS11475	COG1396	sequence-specific DNA binding
HXP40_RS11480	COG3550	peptidyl-serine autophosphorylation
HXP40_RS11495	COG3539	Fimbrial protein
HXP40_RS11500	COG3539	Fimbrial protein
HXP40_RS11505	COG3539	Fimbrial protein
HXP40_RS11510	COG0243	molybdopterin cofactor binding
HXP40_RS11520	COG2207	Transcriptional regulator
HXP40_RS11525	COG3119	arylsulfatase activity
HXP40_RS11530	COG0641	radical SAM
HXP40_RS11540	COG4178	(ABC) transporter
HXP40_RS11545	COG4771	TonB-dependent receptor
HXP40_RS11550	COG0612	Peptidase, M16
HXP40_RS11555	COG0076	glutamate decarboxylase activity
HXP40_RS11560	COG0531	amino acid
HXP40_RS11565	COG1649	PFAM Uncharacterised BCR, COG1649
HXP40_RS11575	COG3706	GGDEF domain
HXP40_RS11580	COG2199	diguanylate cyclase activity
HXP40_RS11580	COG2200	EAL domain
HXP40_RS11580	COG2202	Pas domain
HXP40_RS11585	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HXP40_RS11590	COG0747	negative chemotaxis
HXP40_RS11595	COG0601	transmembrane transport
HXP40_RS11600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HXP40_RS11605	COG0444	Belongs to the ABC transporter superfamily
HXP40_RS11610	COG4608	Belongs to the ABC transporter superfamily
HXP40_RS11615	COG1764	response to oxidative stress
HXP40_RS11635	COG1064	alcohol dehydrogenase
HXP40_RS11640	COG3093	addiction module antidote protein HigA
HXP40_RS11645	COG2864	formate dehydrogenase
HXP40_RS11650	COG0437	4 iron, 4 sulfur cluster binding
HXP40_RS11660	COG0697	spore germination
HXP40_RS11665	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HXP40_RS11675	COG2223	nitrite transmembrane transporter activity
HXP40_RS11685	COG1140	nitrate reductase beta subunit
HXP40_RS11690	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HXP40_RS11695	COG2181	nitrate reductase activity
HXP40_RS11700	COG0384	phenazine biosynthesis protein PhzF
HXP40_RS11705	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HXP40_RS11710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HXP40_RS11720	COG5433	transposase activity
HXP40_RS11740	COG3209	COG3209 Rhs family protein
HXP40_RS11755	COG0625	glutathione transferase activity
HXP40_RS11760	COG1113	amino acid transport
HXP40_RS11765	COG3391	amine dehydrogenase activity
HXP40_RS11770	COG4772	TonB-dependent receptor
HXP40_RS11775	COG1802	Transcriptional regulator
HXP40_RS11780	COG2130	NADP-dependent
HXP40_RS11785	COG1247	-acetyltransferase
HXP40_RS11790	COG3238	Protein conserved in bacteria
HXP40_RS11815	COG1177	transmembrane transport
HXP40_RS11820	COG1176	ABC-type spermidine putrescine transport system, permease component I
HXP40_RS11825	COG3842	ATPase activity
HXP40_RS11830	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HXP40_RS11835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HXP40_RS11840	COG1598	PFAM Uncharacterised protein family UPF0150
HXP40_RS11845	COG1724	mRNA binding
HXP40_RS11855	COG0826	peptidase U32
HXP40_RS11860	COG1396	sequence-specific DNA binding
HXP40_RS11865	COG3135	benzoate transporter
HXP40_RS11870	COG0675	Transposase, IS605 OrfB family
HXP40_RS11885	COG0500	methyltransferase
HXP40_RS11890	COG1275	C4-dicarboxylate transporter malic acid transport protein
HXP40_RS11895	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HXP40_RS11900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HXP40_RS11905	COG2841	Protein conserved in bacteria
HXP40_RS11915	COG5383	Protein conserved in bacteria
HXP40_RS11920	COG0583	DNA-binding transcription factor activity
HXP40_RS11925	COG0840	transmembrane signaling receptor activity
HXP40_RS11940	COG3038	cytochrome b561
HXP40_RS11950	COG1012	belongs to the aldehyde dehydrogenase family
HXP40_RS11955	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HXP40_RS11960	COG1643	Atp-dependent helicase
HXP40_RS11970	COG0671	phosphoesterase, PA-phosphatase related
HXP40_RS11970	COG2453	phosphatase
HXP40_RS11975	COG2267	carboxylic ester hydrolase activity
HXP40_RS11980	COG4589	Belongs to the CDS family
HXP40_RS11985	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HXP40_RS11995	COG0667	Aldo Keto reductase
HXP40_RS12020	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HXP40_RS12025	COG3327	negative regulation of DNA-templated transcription, initiation
HXP40_RS12030	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HXP40_RS12035	COG0183	Belongs to the thiolase family
HXP40_RS12040	COG2050	protein possibly involved in aromatic compounds catabolism
HXP40_RS12045	COG1250	3-hydroxyacyl-CoA dehydrogenase
HXP40_RS12050	COG1024	Enoyl-CoA hydratase
HXP40_RS12055	COG1024	Enoyl-CoA hydratase
HXP40_RS12060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HXP40_RS12065	COG2151	metal-sulfur cluster biosynthetic enzyme
HXP40_RS12070	COG3396	Phenylacetate-CoA oxygenase
HXP40_RS12075	COG3460	Phenylacetate-CoA oxygenase
HXP40_RS12080	COG3396	Phenylacetate-CoA oxygenase
HXP40_RS12085	COG1012	belongs to the aldehyde dehydrogenase family
HXP40_RS12085	COG2030	dehydratase
HXP40_RS12090	COG3733	amine oxidase
HXP40_RS12095	COG1012	belongs to the aldehyde dehydrogenase family
HXP40_RS12100	COG2207	Transcriptional regulator
HXP40_RS12105	COG3784	Protein of unknown function (DUF1318)
HXP40_RS12115	COG2911	Protein conserved in bacteria
HXP40_RS12120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HXP40_RS12125	COG3187	Heat shock protein
HXP40_RS12130	COG3042	response to heat
HXP40_RS12135	COG1013	pyruvate-flavodoxin oxidoreductase activity
HXP40_RS12135	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HXP40_RS12135	COG0674	pyruvate-flavodoxin oxidoreductase activity
HXP40_RS12135	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HXP40_RS12140	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HXP40_RS12145	COG0589	response to stress
HXP40_RS12155	COG0513	Belongs to the DEAD box helicase family
HXP40_RS12165	COG3706	GGDEF domain
HXP40_RS12170	COG2840	Smr protein MutS2
HXP40_RS12175	COG0583	DNA-binding transcription factor activity
HXP40_RS12180	COG1473	amidohydrolase
HXP40_RS12185	COG1473	amidohydrolase
HXP40_RS12190	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HXP40_RS12195	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HXP40_RS12200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HXP40_RS12205	COG0589	response to stress
HXP40_RS12210	COG3182	Iron-regulated membrane protein
HXP40_RS12215	COG0668	transmembrane transport
HXP40_RS12220	COG4166	transmembrane transport
HXP40_RS12225	COG0583	DNA-binding transcription factor activity
HXP40_RS12230	COG1073	alpha beta
HXP40_RS12240	COG2866	Carboxypeptidase
HXP40_RS12245	COG4948	Mandelate Racemase Muconate Lactonizing
HXP40_RS12250	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HXP40_RS12255	COG3283	Transcriptional regulator of aromatic amino acids metabolism
HXP40_RS12265	COG3106	COG3106 Predicted ATPase
HXP40_RS12270	COG1609	Transcriptional regulator
HXP40_RS12280	COG3842	ATPase activity
HXP40_RS12285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HXP40_RS12290	COG1554	hydrolase, family 65, central catalytic
HXP40_RS12295	COG0673	inositol 2-dehydrogenase activity
HXP40_RS12300	COG1082	Xylose isomerase domain protein TIM barrel
HXP40_RS12305	COG1063	alcohol dehydrogenase
HXP40_RS12310	COG0395	ABC-type sugar transport system, permease component
HXP40_RS12315	COG1175	transmembrane transport
HXP40_RS12325	COG0366	Alpha amylase catalytic
HXP40_RS12330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HXP40_RS12340	COG1983	PspC domain protein
HXP40_RS12350	COG1842	Phage shock protein A
HXP40_RS12355	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HXP40_RS12360	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HXP40_RS12365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HXP40_RS12370	COG1012	belongs to the aldehyde dehydrogenase family
HXP40_RS12375	COG1396	sequence-specific DNA binding
HXP40_RS12375	COG1917	Cupin 2, conserved barrel domain protein
HXP40_RS12380	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HXP40_RS12385	COG0174	glutamine synthetase
HXP40_RS12395	COG0531	amino acid
HXP40_RS12405	COG4166	transmembrane transport
HXP40_RS12410	COG4168	peptide transport system, permease
HXP40_RS12415	COG4171	peptide transport system, permease
HXP40_RS12420	COG4172	Belongs to the ABC transporter superfamily
HXP40_RS12425	COG4172	Belongs to the ABC transporter superfamily
HXP40_RS12430	COG2852	Protein conserved in bacteria
HXP40_RS12435	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HXP40_RS12440	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HXP40_RS12440	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HXP40_RS12455	COG5001	Diguanylate cyclase
HXP40_RS12465	COG1349	DNA-binding transcription factor activity
HXP40_RS12475	COG0023	Translation Initiation Factor
HXP40_RS12485	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HXP40_RS12490	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HXP40_RS12495	COG0671	phosphoesterase, PA-phosphatase related
HXP40_RS12505	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HXP40_RS12530	COG0583	DNA-binding transcription factor activity
HXP40_RS12535	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HXP40_RS12545	COG0616	signal peptide processing
HXP40_RS12550	COG1028	Short-chain dehydrogenase reductase Sdr
HXP40_RS12555	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HXP40_RS12560	COG1187	pseudouridine synthase activity
HXP40_RS12565	COG4907	membrane protein (DUF2207)
HXP40_RS12570	COG0009	L-threonylcarbamoyladenylate synthase
HXP40_RS12575	COG0613	PHP domain protein
HXP40_RS12585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HXP40_RS12590	COG0512	Glutamine amidotransferase of anthranilate synthase
HXP40_RS12590	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HXP40_RS12595	COG0134	indole-3-glycerol-phosphate synthase activity
HXP40_RS12595	COG0135	phosphoribosylanthranilate isomerase activity
HXP40_RS12610	COG3729	General stress protein
HXP40_RS12615	COG3685	Protein conserved in bacteria
HXP40_RS12620	COG3685	Protein conserved in bacteria
HXP40_RS12625	COG3047	cAMP biosynthetic process
HXP40_RS12645	COG1607	acyl-coa hydrolase
HXP40_RS12650	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HXP40_RS12655	COG2350	Protein conserved in bacteria
HXP40_RS12660	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HXP40_RS12680	COG4608	Belongs to the ABC transporter superfamily
HXP40_RS12685	COG0444	Belongs to the ABC transporter superfamily
HXP40_RS12690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HXP40_RS12695	COG0601	transmembrane transport
HXP40_RS12700	COG4166	transmembrane transport
HXP40_RS12705	COG2095	MarC family integral membrane protein
HXP40_RS12710	COG1454	alcohol dehydrogenase
HXP40_RS12710	COG1012	belongs to the aldehyde dehydrogenase family
HXP40_RS12720	COG1435	thymidine kinase activity
HXP40_RS12730	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HXP40_RS12735	COG0745	RESPONSE REGULATOR receiver
HXP40_RS12740	COG1752	Esterase of the alpha-beta hydrolase superfamily
HXP40_RS12750	COG0788	formyltetrahydrofolate deformylase activity
HXP40_RS12785	COG2181	nitrate reductase activity
HXP40_RS12790	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HXP40_RS12795	COG1140	nitrate reductase beta subunit
HXP40_RS12800	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HXP40_RS12805	COG2223	nitrite transmembrane transporter activity
HXP40_RS12810	COG3850	Histidine kinase
HXP40_RS12815	COG2197	response regulator
HXP40_RS12820	COG4932	domain protein
HXP40_RS12825	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HXP40_RS12830	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HXP40_RS12835	COG4572	Cation transport regulator
HXP40_RS12840	COG0387	Pfam Sodium calcium exchanger
HXP40_RS12865	COG2912	Transglutaminase-like superfamily
HXP40_RS12870	COG3094	Invasion gene expression up-regulator, SirB
HXP40_RS12875	COG2890	protein-(glutamine-N5) methyltransferase activity
HXP40_RS12900	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HXP40_RS12905	COG0659	secondary active sulfate transmembrane transporter activity
HXP40_RS12920	COG0012	GTP binding
HXP40_RS12925	COG3468	outer membrane autotransporter barrel domain protein
HXP40_RS12930	COG3284	Transcriptional regulator
HXP40_RS12935	COG2376	Dihydroxyacetone kinase
HXP40_RS12940	COG1461	Dihydroxyacetone kinase
HXP40_RS12945	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
HXP40_RS12945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HXP40_RS12945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HXP40_RS12960	COG2261	transglycosylase associated protein
HXP40_RS12965	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HXP40_RS12975	COG1619	proteins homologs of microcin C7 resistance protein MccF
HXP40_RS12985	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HXP40_RS12995	COG2719	SpoVR family
HXP40_RS13010	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HXP40_RS13015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HXP40_RS13020	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HXP40_RS13035	COG0179	Fumarylacetoacetate (FAA) hydrolase
HXP40_RS13060	COG2894	cell division
HXP40_RS13110	COG2200	EAL domain
HXP40_RS13135	COG2200	EAL domain
HXP40_RS13140	COG0789	Transcriptional regulator
HXP40_RS13145	COG5562	phage envelope protein
HXP40_RS13165	COG0538	isocitrate dehydrogenase activity
HXP40_RS13170	COG1187	pseudouridine synthase activity
HXP40_RS13190	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HXP40_RS13195	COG0745	RESPONSE REGULATOR receiver
HXP40_RS13200	COG2205	protein histidine kinase activity
HXP40_RS13205	COG2850	peptidyl-arginine hydroxylation
HXP40_RS13215	COG3842	ATPase activity
HXP40_RS13230	COG0500	methyltransferase
HXP40_RS13250	COG3344	reverse transcriptase
HXP40_RS13385	COG3772	lysozyme
HXP40_RS13430	COG0484	heat shock protein binding
HXP40_RS13435	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HXP40_RS13440	COG1403	HNH endonuclease
HXP40_RS13520	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HXP40_RS13530	COG0582	viral genome integration into host DNA
HXP40_RS13535	COG1177	transmembrane transport
HXP40_RS13540	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HXP40_RS13550	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HXP40_RS13555	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HXP40_RS13565	COG4591	ABC-type transport system involved in lipoprotein release permease component
HXP40_RS13570	COG1136	(ABC) transporter
HXP40_RS13575	COG4591	ABC-type transport system involved in lipoprotein release permease component
HXP40_RS13580	COG4763	Acyl-transferase
HXP40_RS13585	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HXP40_RS13590	COG1376	ErfK ybiS ycfS ynhG family protein
HXP40_RS13590	COG1388	LysM domain
HXP40_RS13600	COG1309	transcriptional regulator
HXP40_RS13605	COG3134	Outer membrane lipoprotein
HXP40_RS13610	COG1252	NADH dehydrogenase
HXP40_RS13630	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
HXP40_RS13635	COG5633	Lipoprotein
HXP40_RS13640	COG0537	adenosine 5'-monophosphoramidase activity
HXP40_RS13645	COG4773	Receptor
HXP40_RS13650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HXP40_RS13650	COG1263	PTS System
HXP40_RS13655	COG0084	hydrolase, TatD family'
HXP40_RS13660	COG0470	DNA polymerase III
HXP40_RS13670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HXP40_RS13675	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HXP40_RS13680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HXP40_RS13690	COG1028	Short-chain dehydrogenase reductase Sdr
HXP40_RS13695	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HXP40_RS13715	COG1399	metal-binding, possibly nucleic acid-binding protein
HXP40_RS13720	COG0424	maF-like protein
HXP40_RS13725	COG0564	pseudouridine synthase activity
HXP40_RS13735	COG1530	ribonuclease E activity
HXP40_RS13740	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HXP40_RS13745	COG1256	bacterial-type flagellum assembly
HXP40_RS13750	COG1705	Flagellar rod assembly protein muramidase FlgJ
HXP40_RS13750	COG3951	Flagellar rod assembly protein muramidase FlgJ
HXP40_RS13765	COG4786	Flagellar basal body rod
HXP40_RS13770	COG4787	bacterial-type flagellum-dependent cell motility
HXP40_RS13775	COG1749	Flagellar hook protein flgE
HXP40_RS13780	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HXP40_RS13785	COG1558	bacterial-type flagellum-dependent cell motility
HXP40_RS13790	COG1815	bacterial-type flagellum-dependent cell motility
HXP40_RS13795	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
HXP40_RS13800	COG2747	anti-sigma28 factor FlgM
HXP40_RS13805	COG3418	PFAM FlgN family protein
HXP40_RS13810	COG0728	peptidoglycan biosynthetic process
HXP40_RS13815	COG0673	inositol 2-dehydrogenase activity
HXP40_RS13825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HXP40_RS13835	COG2999	glutathione oxidoreductase activity
HXP40_RS13870	COG3038	cytochrome b561
HXP40_RS13875	COG2353	YceI-like domain
HXP40_RS13885	COG1560	Kdo2-lipid A biosynthetic process
HXP40_RS13900	COG5645	(Lipo)protein
HXP40_RS13905	COG2943	transferase activity, transferring hexosyl groups
HXP40_RS13920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HXP40_RS13925	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HXP40_RS13950	COG2197	response regulator
HXP40_RS13965	COG1462	curli production assembly transport component CsgG
HXP40_RS13975	COG3381	protein complex oligomerization
HXP40_RS14015	COG3706	GGDEF domain
HXP40_RS14020	COG0457	Tetratricopeptide repeat
HXP40_RS14025	COG1649	PFAM Uncharacterised BCR, COG1649
HXP40_RS14025	COG0726	polysaccharide deacetylase
HXP40_RS14030	COG1215	transferase activity, transferring glycosyl groups
HXP40_RS14035	COG3658	cytochrome
HXP40_RS14040	COG1702	phosphate starvation-inducible protein PhoH
HXP40_RS14045	COG2837	iron assimilation
HXP40_RS14050	COG2822	iron ion transport
HXP40_RS14060	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HXP40_RS14070	COG0506	proline dehydrogenase activity
HXP40_RS14070	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HXP40_RS14070	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HXP40_RS14075	COG1309	transcriptional regulator
HXP40_RS14110	COG2233	PERMEase
HXP40_RS14115	COG3729	General stress protein
HXP40_RS14150	COG3381	protein complex oligomerization
HXP40_RS14155	COG0243	molybdopterin cofactor binding
HXP40_RS14160	COG3005	denitrification pathway
HXP40_RS14165	COG0745	RESPONSE REGULATOR receiver
HXP40_RS14170	COG1879	ABC-type sugar transport system periplasmic component
HXP40_RS14175	COG0784	Response regulator, receiver
HXP40_RS14175	COG2205	protein histidine kinase activity
HXP40_RS14175	COG2198	Histidine kinase
HXP40_RS14180	COG0348	domain, Protein
HXP40_RS14200	COG1278	Cold shock
HXP40_RS14205	COG1278	Cold shock
HXP40_RS14225	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HXP40_RS14230	COG1596	polysaccharide export
HXP40_RS14235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HXP40_RS14240	COG0489	protein tyrosine kinase activity
HXP40_RS14240	COG3206	protein involved in exopolysaccharide biosynthesis
HXP40_RS14255	COG1294	oxidase, subunit
HXP40_RS14260	COG1271	oxidase subunit
HXP40_RS14265	COG1773	rubredoxin
HXP40_RS14270	COG1999	signal sequence binding
HXP40_RS14275	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HXP40_RS14280	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
HXP40_RS14285	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HXP40_RS14290	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HXP40_RS14300	COG0670	Belongs to the BI1 family
HXP40_RS14305	COG2920	part of a sulfur-relay system
HXP40_RS14310	COG1254	Belongs to the acylphosphatase family
HXP40_RS14325	COG1832	CoA-binding protein
HXP40_RS14340	COG0210	DNA helicase
HXP40_RS14345	COG3304	Inner membrane component domain
HXP40_RS14350	COG1289	transmembrane transporter activity
HXP40_RS14355	COG3070	regulator of competence-specific genes
HXP40_RS14365	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HXP40_RS14365	COG2885	chlorophyll binding
HXP40_RS14375	COG1067	ATP-dependent peptidase activity
HXP40_RS14385	COG3130	regulation of translation
HXP40_RS14390	COG3009	Protein conserved in bacteria
HXP40_RS14395	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HXP40_RS14395	COG3008	intermembrane lipid transfer
HXP40_RS14400	COG2995	paraquat-inducible protein a
HXP40_RS14405	COG0488	(ABC) transporter
HXP40_RS14415	COG3217	Mosc domain protein beta barrel domain protein
HXP40_RS14415	COG0633	Ferredoxin
HXP40_RS14430	COG3121	Chaperone
HXP40_RS14435	COG3539	Fimbrial protein
HXP40_RS14440	COG3539	Fimbrial protein
HXP40_RS14445	COG3539	Fimbrial protein
HXP40_RS14450	COG3188	usher protein
HXP40_RS14455	COG3121	Chaperone
HXP40_RS14460	COG3539	Fimbrial protein
HXP40_RS14465	COG0431	NADPH-dependent FMN reductase
HXP40_RS14470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HXP40_RS14480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HXP40_RS14485	COG1116	anion transmembrane transporter activity
HXP40_RS14490	COG0308	aminopeptidase N
HXP40_RS14510	COG1448	Aminotransferase
HXP40_RS14515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HXP40_RS14520	COG3108	Peptidase M15
HXP40_RS14525	COG2989	Protein conserved in bacteria
HXP40_RS14535	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HXP40_RS14545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HXP40_RS14550	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HXP40_RS14555	COG3173	Aminoglycoside phosphotransferase
HXP40_RS14570	COG3214	Protein conserved in bacteria
HXP40_RS14575	COG1663	tetraacyldisaccharide 4'-kinase activity
HXP40_RS14580	COG1132	(ABC) transporter
HXP40_RS14585	COG0658	competence protein
HXP40_RS14585	COG2333	competence protein COMEC
HXP40_RS14595	COG0539	negative regulation of cytoplasmic translation
HXP40_RS14605	COG0501	Belongs to the peptidase M48B family
HXP40_RS14620	COG2323	membrane
HXP40_RS14625	COG1944	ATP diphosphatase activity
HXP40_RS14630	COG2116	formate transmembrane transporter activity
HXP40_RS14635	COG1882	Formate acetyltransferase
HXP40_RS14640	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HXP40_RS14645	COG2249	NAD(P)H dehydrogenase (quinone) activity
HXP40_RS14650	COG0583	DNA-binding transcription factor activity
HXP40_RS14655	COG0531	amino acid
HXP40_RS14665	COG1335	isochorismatase
HXP40_RS14670	COG3302	dmso reductase anchor subunit
HXP40_RS14675	COG0437	4 iron, 4 sulfur cluster binding
HXP40_RS14680	COG0243	molybdopterin cofactor binding
HXP40_RS14690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HXP40_RS14700	COG1178	ABC-type Fe3 transport system permease component
HXP40_RS14700	COG1674	ftsk spoiiie
HXP40_RS14705	COG1522	sequence-specific DNA binding
HXP40_RS14710	COG0492	ferredoxin-NADP+ reductase activity
HXP40_RS14715	COG4988	ABC transporter
HXP40_RS14720	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HXP40_RS14740	COG0542	response to heat
HXP40_RS14750	COG1278	Cold shock
HXP40_RS14755	COG1136	(ABC) transporter
HXP40_RS14755	COG0577	efflux transmembrane transporter activity
HXP40_RS14760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HXP40_RS14765	COG2990	Protein conserved in bacteria
HXP40_RS14770	COG3593	DNA synthesis involved in DNA repair
HXP40_RS14780	COG2431	L-lysine efflux transmembrane transporter activity
HXP40_RS14790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HXP40_RS14795	COG0028	Belongs to the TPP enzyme family
HXP40_RS14800	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HXP40_RS14805	COG0702	epimerase
HXP40_RS14810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HXP40_RS14815	COG3023	N-Acetylmuramoyl-L-alanine amidase
HXP40_RS14830	COG1126	abc transporter atp-binding protein
HXP40_RS14835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HXP40_RS14840	COG4215	(ABC) transporter
HXP40_RS14845	COG4160	amino acid transport
HXP40_RS14850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HXP40_RS14865	COG1177	transmembrane transport
HXP40_RS14870	COG1176	ABC-type spermidine putrescine transport system, permease component I
HXP40_RS14875	COG3842	ATPase activity
HXP40_RS14880	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HXP40_RS14895	COG0778	Nitroreductase
HXP40_RS14905	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HXP40_RS14920	COG3226	Transcriptional regulator
HXP40_RS14925	COG0738	Major facilitator superfamily
HXP40_RS14930	COG0561	phosphatase activity
HXP40_RS14940	COG2814	Major facilitator Superfamily
HXP40_RS14945	COG0671	phosphoesterase, PA-phosphatase related
HXP40_RS14950	COG1349	DNA-binding transcription factor activity
HXP40_RS14955	COG1686	Belongs to the peptidase S11 family
HXP40_RS14960	COG0625	glutathione transferase activity
HXP40_RS14965	COG2133	pyrroloquinoline quinone binding
HXP40_RS14980	COG2199	diguanylate cyclase activity
HXP40_RS14990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HXP40_RS15000	COG0747	negative chemotaxis
HXP40_RS15005	COG4172	Belongs to the ABC transporter superfamily
HXP40_RS15010	COG1446	asparaginase
HXP40_RS15015	COG0303	'Molybdopterin
HXP40_RS15020	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HXP40_RS15025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HXP40_RS15030	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HXP40_RS15035	COG1882	Formate acetyltransferase
HXP40_RS15040	COG0561	phosphatase activity
HXP40_RS15050	COG0488	(ABC) transporter
HXP40_RS15055	COG1376	ErfK ybiS ycfS ynhG family protein
HXP40_RS15060	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HXP40_RS15065	COG1321	iron dependent repressor
HXP40_RS15075	COG2194	sulfuric ester hydrolase activity
HXP40_RS15080	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HXP40_RS15090	COG5006	permease, DMT superfamily
HXP40_RS15100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HXP40_RS15105	COG0765	amino acid transport
HXP40_RS15110	COG1126	abc transporter atp-binding protein
HXP40_RS15115	COG0668	transmembrane transport
HXP40_RS15130	COG4774	siderophore transport
HXP40_RS15140	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HXP40_RS15150	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HXP40_RS15155	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HXP40_RS15160	COG1199	ATP-dependent helicase activity
HXP40_RS15165	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
HXP40_RS15170	COG0513	Belongs to the DEAD box helicase family
HXP40_RS15175	COG1309	transcriptional regulator
HXP40_RS15185	COG1131	(ABC) transporter
HXP40_RS15190	COG0842	Transport permease protein
HXP40_RS15195	COG0842	Transport permease protein
HXP40_RS15205	COG3568	Endonuclease Exonuclease Phosphatase
HXP40_RS15210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HXP40_RS15215	COG0392	lysyltransferase activity
HXP40_RS15220	COG0670	Belongs to the BI1 family
HXP40_RS15225	COG0670	Belongs to the BI1 family
HXP40_RS15230	COG0314	molybdopterin synthase activity
HXP40_RS15235	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HXP40_RS15245	COG0521	Mo-molybdopterin cofactor biosynthetic process
HXP40_RS15255	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HXP40_RS15265	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HXP40_RS15270	COG2226	methyltransferase
HXP40_RS15285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HXP40_RS15290	COG1881	PFAM PEBP family protein
HXP40_RS15295	COG4677	pectinesterase activity
HXP40_RS15300	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HXP40_RS15305	COG0471	metal ion transport
HXP40_RS15310	COG2828	Protein conserved in bacteria
HXP40_RS15315	COG0583	DNA-binding transcription factor activity
HXP40_RS15325	COG0561	phosphatase activity
HXP40_RS15330	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HXP40_RS15335	COG4149	molybdate abc transporter
HXP40_RS15340	COG0725	ABC transporter, periplasmic molybdate-binding protein
HXP40_RS15350	COG2005	Transcriptional regulator
HXP40_RS15350	COG3585	molybdate ion transport
HXP40_RS15355	COG1119	ATPase activity
HXP40_RS15360	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HXP40_RS15365	COG1085	galactose-1-phosphate uridylyltransferase
HXP40_RS15375	COG2017	converts alpha-aldose to the beta-anomer
HXP40_RS15385	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HXP40_RS15395	COG1230	cation diffusion facilitator family transporter
HXP40_RS15400	COG3201	nicotinamide mononucleotide transporter
HXP40_RS15450	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HXP40_RS15455	COG2885	chlorophyll binding
HXP40_RS15465	COG3064	Membrane
HXP40_RS15470	COG0848	biopolymer transport protein
HXP40_RS15475	COG0811	peptide transport
HXP40_RS15480	COG0824	Thioesterase
HXP40_RS15485	COG3790	cyd operon protein YbgE
HXP40_RS15490	COG4890	Cyd operon protein YbgT
HXP40_RS15495	COG1294	oxidase, subunit
HXP40_RS15500	COG1271	oxidase subunit
HXP40_RS15510	COG0383	alpha-mannosidase activity
HXP40_RS15515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HXP40_RS15515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HXP40_RS15515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HXP40_RS15520	COG2188	Transcriptional regulator
HXP40_RS15525	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HXP40_RS15535	COG0508	dehydrogenase complex catalyzes the overall conversion of
HXP40_RS15540	COG0567	Dehydrogenase, E1 component
HXP40_RS15545	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HXP40_RS15550	COG1053	succinate dehydrogenase
HXP40_RS15555	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HXP40_RS15560	COG2009	succinate dehydrogenase
HXP40_RS15570	COG0372	Belongs to the citrate synthase family
HXP40_RS15575	COG3539	Fimbrial protein
HXP40_RS15580	COG3188	usher protein
HXP40_RS15585	COG3121	Chaperone
HXP40_RS15590	COG3539	Fimbrial protein
HXP40_RS15595	COG3180	Ammonia monooxygenase
HXP40_RS15610	COG1984	allophanate hydrolase subunit 2
HXP40_RS15615	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HXP40_RS15620	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HXP40_RS15625	COG3104	oligopeptide transport
HXP40_RS15630	COG0415	Belongs to the DNA photolyase family
HXP40_RS15635	COG3272	Protein of unknown function (DUF1722)
HXP40_RS15670	COG3209	COG3209 Rhs family protein
HXP40_RS15700	COG2205	protein histidine kinase activity
HXP40_RS15705	COG0745	RESPONSE REGULATOR receiver
HXP40_RS15720	COG0531	amino acid
HXP40_RS15740	COG0033	Phosphoglucomutase
HXP40_RS15745	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HXP40_RS15750	COG0596	Alpha beta hydrolase
HXP40_RS15760	COG0716	FMN binding
HXP40_RS15770	COG0735	belongs to the Fur family
HXP40_RS15790	COG1263	PTS System
HXP40_RS15790	COG2190	(PTS) system
HXP40_RS15790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HXP40_RS15800	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HXP40_RS15805	COG1940	carbohydrate kinase activity
HXP40_RS15805	COG1846	Transcriptional regulator
HXP40_RS15810	COG0647	UMP catabolic process
HXP40_RS15815	COG0367	asparagine synthase
HXP40_RS15855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HXP40_RS15865	COG1702	phosphate starvation-inducible protein PhoH
HXP40_RS15875	COG4535	Mg2 and Co2 transporter CorC
HXP40_RS15880	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HXP40_RS15885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HXP40_RS15890	COG0765	amino acid transport
HXP40_RS15895	COG0765	amino acid transport
HXP40_RS15900	COG1126	abc transporter atp-binding protein
HXP40_RS15910	COG0443	Heat shock 70 kDa protein
HXP40_RS15915	COG2214	Heat shock protein DnaJ domain protein
HXP40_RS15925	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HXP40_RS15930	COG2214	Heat shock protein DnaJ domain protein
HXP40_RS15940	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HXP40_RS15945	COG2888	peptidyl-tyrosine sulfation
HXP40_RS15960	COG1466	dna polymerase III delta subunit
HXP40_RS15970	COG0406	alpha-ribazole phosphatase activity
HXP40_RS15975	COG0799	negative regulation of ribosome biogenesis
HXP40_RS15985	COG0768	penicillin binding
HXP40_RS15990	COG0772	Belongs to the SEDS family
HXP40_RS15995	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HXP40_RS16000	COG1686	Belongs to the peptidase S11 family
HXP40_RS16015	COG0583	DNA-binding transcription factor activity
HXP40_RS16025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HXP40_RS16050	COG3069	C4-dicarboxylate transmembrane transporter activity
HXP40_RS16055	COG4565	transcriptional regulatory protein
HXP40_RS16060	COG3290	protein histidine kinase activity
HXP40_RS16065	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HXP40_RS16075	COG2301	Belongs to the HpcH HpaI aldolase family
HXP40_RS16080	COG3051	citrate lyase alpha subunit
HXP40_RS16095	COG0471	metal ion transport
HXP40_RS16100	COG3719	Belongs to the RNase T2 family
HXP40_RS16105	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HXP40_RS16110	COG1063	alcohol dehydrogenase
HXP40_RS16115	COG0589	response to stress
HXP40_RS16120	COG3634	alkyl hydroperoxide reductase activity
HXP40_RS16125	COG0450	alkyl hydroperoxide reductase
HXP40_RS16130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HXP40_RS16135	COG0583	DNA-binding transcription factor activity
HXP40_RS16140	COG3969	phosphoadenosine phosphosulfate
HXP40_RS16145	COG1475	DNA binding
HXP40_RS16150	COG0436	Aminotransferase
HXP40_RS16155	COG0371	Dehydrogenase
HXP40_RS16160	COG2879	small protein
HXP40_RS16165	COG1966	Carbon starvation protein
HXP40_RS16170	COG2050	protein possibly involved in aromatic compounds catabolism
HXP40_RS16175	COG1028	Short-chain dehydrogenase reductase Sdr
HXP40_RS16180	COG3433	isochorismatase activity
HXP40_RS16180	COG1535	isochorismatase
HXP40_RS16185	COG1021	2,3-dihydroxybenzoate-AMP ligase
HXP40_RS16190	COG1169	isochorismate synthase
HXP40_RS16195	COG4592	Periplasmic binding protein
HXP40_RS16205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HXP40_RS16210	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HXP40_RS16215	COG1120	ATPase activity
HXP40_RS16220	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HXP40_RS16225	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HXP40_RS16225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HXP40_RS16230	COG3251	PFAM MbtH domain protein
HXP40_RS16235	COG2382	esterase
HXP40_RS16245	COG4771	TonB-dependent receptor
HXP40_RS16250	COG2977	Belongs to the P-Pant transferase superfamily
HXP40_RS16255	COG3385	transposase activity
HXP40_RS16290	COG3423	Transcriptional regulator
HXP40_RS16310	COG0500	methyltransferase
HXP40_RS16315	COG0438	transferase activity, transferring glycosyl groups
HXP40_RS16320	COG0438	transferase activity, transferring glycosyl groups
HXP40_RS16360	COG0778	Nitroreductase
HXP40_RS16365	COG0668	transmembrane transport
HXP40_RS16370	COG1113	amino acid transport
HXP40_RS16375	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HXP40_RS16380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HXP40_RS16385	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HXP40_RS16390	COG1538	Outer membrane efflux protein
HXP40_RS16395	COG0745	RESPONSE REGULATOR receiver
HXP40_RS16400	COG5002	protein histidine kinase activity
HXP40_RS16405	COG1215	transferase activity, transferring glycosyl groups
HXP40_RS16410	COG4783	chaperone-mediated protein folding
HXP40_RS16420	COG2207	Transcriptional regulator
HXP40_RS16430	COG2197	response regulator
HXP40_RS16435	COG3539	Fimbrial protein
HXP40_RS16440	COG3539	Fimbrial protein
HXP40_RS16445	COG3188	usher protein
HXP40_RS16450	COG3121	Chaperone
HXP40_RS16455	COG3539	Fimbrial protein
HXP40_RS16465	COG2501	S4 domain
HXP40_RS16470	COG1988	membrane-bound metal-dependent
HXP40_RS16480	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HXP40_RS16490	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HXP40_RS16495	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HXP40_RS16500	COG0549	Belongs to the carbamate kinase family
HXP40_RS16510	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HXP40_RS16515	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HXP40_RS16520	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HXP40_RS16525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HXP40_RS16530	COG3257	ureidoglycine aminohydrolase activity
HXP40_RS16535	COG1929	Belongs to the glycerate kinase type-1 family
HXP40_RS16540	COG2233	PERMEase
HXP40_RS16550	COG1953	Uracil, thiamine, allantoin
HXP40_RS16555	COG2084	Dehydrogenase
HXP40_RS16565	COG3960	tartronate-semialdehyde synthase activity
HXP40_RS16570	COG1414	Transcriptional regulator
HXP40_RS16580	COG0583	DNA-binding transcription factor activity
HXP40_RS16600	COG3209	COG3209 Rhs family protein
HXP40_RS16615	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HXP40_RS16620	COG4181	ATPase activity
HXP40_RS16625	COG2755	lipolytic protein G-D-S-L family
HXP40_RS16630	COG0300	oxidoreductase activity
HXP40_RS16635	COG3118	belongs to the thioredoxin family
HXP40_RS16640	COG0390	transport system, permease component
HXP40_RS16645	COG4619	ABC transporter
HXP40_RS16650	COG0330	HflC and HflK could
HXP40_RS16655	COG1585	Membrane protein implicated in regulation of membrane protease activity
HXP40_RS16660	COG0789	Transcriptional regulator
HXP40_RS16665	COG0531	amino acid
HXP40_RS16670	COG2066	Belongs to the glutaminase family
HXP40_RS16675	COG2217	Heavy metal translocating P-type atpase
HXP40_RS16680	COG3093	addiction module antidote protein HigA
HXP40_RS16685	COG3735	TraB family
HXP40_RS16690	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HXP40_RS16695	COG0737	Belongs to the 5'-nucleotidase family
HXP40_RS16700	COG2223	nitrite transmembrane transporter activity
HXP40_RS16705	COG4651	solute:proton antiporter activity
HXP40_RS16705	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HXP40_RS16710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HXP40_RS16745	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HXP40_RS16755	COG2832	Protein of unknown function (DUF454)
HXP40_RS16760	COG3923	Primosomal replication protein n
HXP40_RS16770	COG3264	Mechanosensitive ion channel
HXP40_RS16770	COG1196	nuclear chromosome segregation
HXP40_RS16780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HXP40_RS16785	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HXP40_RS16800	COG0110	maltose O-acetyltransferase activity
HXP40_RS16810	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HXP40_RS16815	COG5507	3-demethylubiquinone-9 3-methyltransferase
HXP40_RS16825	COG3695	enzyme binding
HXP40_RS16830	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HXP40_RS16835	COG1946	Acyl-CoA thioesterase
HXP40_RS16840	COG0004	ammonium transporteR
HXP40_RS16845	COG0347	Belongs to the P(II) protein family
HXP40_RS16850	COG1132	(ABC) transporter
HXP40_RS16855	COG1132	(ABC) transporter
HXP40_RS16860	COG1522	sequence-specific DNA binding
HXP40_RS16870	COG4533	DNA binding
HXP40_RS16880	COG0824	Thioesterase
HXP40_RS16885	COG1555	photosystem II stabilization
HXP40_RS16890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HXP40_RS16895	COG0776	regulation of translation
HXP40_RS16900	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HXP40_RS16920	COG0271	Belongs to the BolA IbaG family
HXP40_RS16925	COG3056	Lipoprotein
HXP40_RS16930	COG2223	nitrite transmembrane transporter activity
HXP40_RS16935	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HXP40_RS16940	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HXP40_RS16945	COG1845	cytochrome c oxidase, subunit III
HXP40_RS16950	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HXP40_RS16960	COG2814	Major facilitator Superfamily
HXP40_RS16970	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HXP40_RS16975	COG0693	protein deglycase activity
HXP40_RS16990	COG0142	geranyltranstransferase activity
HXP40_RS17000	COG0667	Aldo Keto reductase
HXP40_RS17005	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HXP40_RS17010	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HXP40_RS17025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HXP40_RS17025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HXP40_RS17035	COG4238	major outer membrane lipoprotein
HXP40_RS17040	COG3248	Nucleoside-binding outer membrane protein
HXP40_RS17045	COG1403	HNH endonuclease
HXP40_RS17050	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HXP40_RS17055	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HXP40_RS17060	COG1862	Preprotein translocase
HXP40_RS17080	COG0366	Alpha amylase catalytic
HXP40_RS17085	COG1113	amino acid transport
HXP40_RS17090	COG1114	Component of the transport system for branched-chain amino acids
HXP40_RS17095	COG5002	protein histidine kinase activity
HXP40_RS17100	COG0745	RESPONSE REGULATOR receiver
HXP40_RS17105	COG0420	3'-5' exonuclease activity
HXP40_RS17110	COG0419	ATPase involved in DNA repair
HXP40_RS17115	COG2814	Major facilitator Superfamily
HXP40_RS17120	COG1940	carbohydrate kinase activity
HXP40_RS17145	COG4126	flavin adenine dinucleotide binding
HXP40_RS17165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HXP40_RS17170	COG3706	GGDEF domain
HXP40_RS17180	COG1785	Belongs to the alkaline phosphatase family
HXP40_RS17195	COG1181	Belongs to the D-alanine--D-alanine ligase family
HXP40_RS17215	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HXP40_RS17220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HXP40_RS17225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HXP40_RS17230	COG3468	outer membrane autotransporter barrel domain protein
HXP40_RS17235	COG0113	porphobilinogen synthase activity
HXP40_RS17240	COG2175	clavaminate synthase activity
HXP40_RS17245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HXP40_RS17255	COG4521	taurine ABC transporter
HXP40_RS17265	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HXP40_RS17270	COG1215	transferase activity, transferring glycosyl groups
HXP40_RS17285	COG3547	Transposase (IS116 IS110 IS902 family)
HXP40_RS17305	COG3122	Protein conserved in bacteria
HXP40_RS17310	COG2814	Major facilitator Superfamily
HXP40_RS17325	COG3971	2-oxopent-4-enoate hydratase activity
HXP40_RS17345	COG1414	Transcriptional regulator
HXP40_RS17350	COG1609	Transcriptional regulator
HXP40_RS17355	COG3250	beta-galactosidase activity
HXP40_RS17360	COG2223	nitrite transmembrane transporter activity
HXP40_RS17365	COG0110	maltose O-acetyltransferase activity
HXP40_RS17370	COG2807	transmembrane transport
HXP40_RS17380	COG0288	reversible hydration of carbon dioxide
HXP40_RS17385	COG0583	DNA-binding transcription factor activity
HXP40_RS17390	COG0402	S-adenosylhomocysteine deaminase activity
HXP40_RS17395	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HXP40_RS17400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HXP40_RS17405	COG2079	MmgE PrpD family protein
HXP40_RS17410	COG0372	Belongs to the citrate synthase family
HXP40_RS17415	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HXP40_RS17420	COG3829	transcription factor binding
HXP40_RS17430	COG1280	lysine exporter protein (LysE YggA)
HXP40_RS17445	COG1064	alcohol dehydrogenase
HXP40_RS17450	COG0402	S-adenosylhomocysteine deaminase activity
HXP40_RS17455	COG0549	Belongs to the carbamate kinase family
HXP40_RS17465	COG1304	FMN binding
HXP40_RS17470	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HXP40_RS17480	COG0666	response to abiotic stimulus
HXP40_RS17490	COG0583	DNA-binding transcription factor activity
HXP40_RS17495	COG2771	luxR family
HXP40_RS17495	COG2200	EAL domain
HXP40_RS17505	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HXP40_RS17530	COG1556	Lactate utilization protein
HXP40_RS17535	COG1139	Iron-sulfur cluster binding protein
HXP40_RS17540	COG0247	lactate metabolic process
HXP40_RS17545	COG2207	Transcriptional regulator
HXP40_RS17550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HXP40_RS17560	COG3059	membrane
HXP40_RS17570	COG2207	Transcriptional regulator
HXP40_RS17570	COG3708	Transcriptional regulator
HXP40_RS17575	COG1388	LysM domain
HXP40_RS17615	COG3188	usher protein
HXP40_RS17625	COG3121	Chaperone
HXP40_RS17630	COG0727	PFAM Uncharacterised protein family (UPF0153)
HXP40_RS17635	COG3477	response to acidic pH
HXP40_RS17640	COG2080	2 iron, 2 sulfur cluster binding
HXP40_RS17645	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HXP40_RS17650	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HXP40_RS17655	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HXP40_RS17745	COG3561	AntA/AntB antirepressor
HXP40_RS17760	COG0582	viral genome integration into host DNA
HXP40_RS17780	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HXP40_RS17800	COG2195	Cleaves the N-terminal amino acid of tripeptides
HXP40_RS17815	COG0454	-acetyltransferase
HXP40_RS17825	COG2161	toxin-antitoxin pair type II binding
HXP40_RS17845	COG1943	Transposase
HXP40_RS17850	COG0791	NLP P60 protein
HXP40_RS17855	COG3077	Addiction module antitoxin, RelB DinJ family
HXP40_RS17860	COG3041	Addiction module toxin RelE StbE family
HXP40_RS17865	COG3034	peptidoglycan biosynthetic process
HXP40_RS17870	COG0121	glutamine amidotransferase
HXP40_RS17880	COG1960	acyl-CoA dehydrogenase activity
HXP40_RS17890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HXP40_RS17895	COG5433	transposase activity
HXP40_RS17910	COG3209	COG3209 Rhs family protein
HXP40_RS18000	COG3157	Type VI secretion system effector, Hcp
HXP40_RS18005	COG4104	PAAR repeat-containing protein
HXP40_RS18025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HXP40_RS18035	COG2226	methyltransferase
HXP40_RS18045	COG0741	lytic transglycosylase activity
HXP40_RS18045	COG1388	LysM domain
HXP40_RS18060	COG0583	DNA-binding transcription factor activity
HXP40_RS18065	COG0656	L-ascorbic acid biosynthetic process
HXP40_RS18100	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HXP40_RS18105	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HXP40_RS18110	COG2011	ABC-type metal ion transport system permease component
HXP40_RS18115	COG1464	Belongs to the NlpA lipoprotein family
HXP40_RS18125	COG1720	tRNA m6t6A37 methyltransferase activity
HXP40_RS18135	COG0791	NLP P60 protein
HXP40_RS18140	COG3015	lipoprotein NlpE involved in copper resistance
HXP40_RS18145	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HXP40_RS18150	COG4681	YaeQ
HXP40_RS18160	COG4568	rho-dependent transcription termination
HXP40_RS18165	COG0037	tRNA processing
HXP40_RS18170	COG0346	lactoylglutathione lyase activity
HXP40_RS18175	COG1982	Orn Lys Arg decarboxylase major
HXP40_RS18185	COG0587	DNA-directed DNA polymerase activity
HXP40_RS18210	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HXP40_RS18215	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HXP40_RS18225	COG0750	zinc metalloprotease
HXP40_RS18230	COG0575	Belongs to the CDS family
HXP40_RS18235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HXP40_RS18240	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HXP40_RS18265	COG0024	Methionine aminopeptidase
HXP40_RS18280	COG1408	metallophosphoesterase
HXP40_RS18290	COG3835	regulator
HXP40_RS18295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HXP40_RS18310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HXP40_RS18315	COG2860	membrane
HXP40_RS18340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HXP40_RS18345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HXP40_RS18350	COG1120	ATPase activity
HXP40_RS18355	COG4774	siderophore transport
HXP40_RS18360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HXP40_RS18365	COG1643	Atp-dependent helicase
HXP40_RS18370	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HXP40_RS18380	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HXP40_RS18390	COG0617	tRNA 3'-terminal CCA addition
HXP40_RS18395	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HXP40_RS18400	COG3539	Fimbrial protein
HXP40_RS18405	COG3121	Chaperone
HXP40_RS18410	COG3188	usher protein
HXP40_RS18415	COG3539	Fimbrial protein
HXP40_RS18420	COG3539	Fimbrial protein
HXP40_RS18425	COG3539	Fimbrial protein
HXP40_RS18455	COG5464	transposase or invertase
HXP40_RS18465	COG0726	polysaccharide deacetylase
HXP40_RS18470	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HXP40_RS18475	COG0842	Transport permease protein
HXP40_RS18480	COG1131	(ABC) transporter
HXP40_RS18485	COG0288	reversible hydration of carbon dioxide
HXP40_RS18490	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HXP40_RS18495	COG4993	Dehydrogenase
HXP40_RS18500	COG2132	Multicopper oxidase
HXP40_RS18525	COG1049	propionate catabolic process, 2-methylcitrate cycle
HXP40_RS18530	COG3064	Membrane
HXP40_RS18535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HXP40_RS18540	COG0508	dehydrogenase complex catalyzes the overall conversion of
HXP40_RS18545	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HXP40_RS18550	COG2186	Transcriptional regulator
HXP40_RS18555	COG1113	amino acid transport
HXP40_RS18560	COG3725	Membrane protein required for beta-lactamase induction
HXP40_RS18565	COG3023	N-Acetylmuramoyl-L-alanine amidase
HXP40_RS18570	COG0157	Belongs to the NadC ModD family
HXP40_RS18575	COG4969	Belongs to the N-Me-Phe pilin family
HXP40_RS18580	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HXP40_RS18585	COG1459	type II secretion system
HXP40_RS18600	COG0237	dephospho-CoA kinase activity
HXP40_RS18615	COG0494	nUDIX hydrolase
HXP40_RS18635	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HXP40_RS18640	COG0849	cell division
HXP40_RS18645	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HXP40_RS18650	COG1181	Belongs to the D-alanine--D-alanine ligase family
HXP40_RS18665	COG0772	Belongs to the SEDS family
HXP40_RS18680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HXP40_RS18685	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HXP40_RS18690	COG0768	penicillin binding
HXP40_RS18695	COG3116	cell division
HXP40_RS18705	COG2001	Belongs to the MraZ family
HXP40_RS18710	COG1609	Transcriptional regulator
HXP40_RS18720	COG0440	acetolactate synthase activity
HXP40_RS18725	COG0028	Belongs to the TPP enzyme family
HXP40_RS18735	COG0583	DNA-binding transcription factor activity
HXP40_RS18750	COG0473	3-isopropylmalate dehydrogenase activity
HXP40_RS18765	COG2814	Major facilitator Superfamily
HXP40_RS18775	COG4533	DNA binding
HXP40_RS18780	COG4143	(ABC) transporter
HXP40_RS18785	COG1178	ABC-type Fe3 transport system permease component
HXP40_RS18790	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
HXP40_RS18795	COG0586	Pfam SNARE associated Golgi protein
HXP40_RS18800	COG4977	sequence-specific DNA binding
HXP40_RS18805	COG1069	ribulokinase activity
HXP40_RS18810	COG2160	L-arabinose isomerase activity
HXP40_RS18815	COG0235	Class ii aldolase
HXP40_RS18820	COG0417	DNA replication proofreading
HXP40_RS18830	COG0564	pseudouridine synthase activity
HXP40_RS18850	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HXP40_RS18855	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HXP40_RS18860	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HXP40_RS18885	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HXP40_RS18900	COG2271	Major facilitator Superfamily
HXP40_RS18905	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HXP40_RS18910	COG0644	oxidoreductase
HXP40_RS18960	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HXP40_RS18965	COG0505	Belongs to the CarA family
HXP40_RS18985	COG1047	Peptidyl-prolyl cis-trans
HXP40_RS19000	COG0196	riboflavin kinase activity
HXP40_RS19030	COG0583	DNA-binding transcription factor activity
HXP40_RS19050	COG3385	transposase activity
HXP40_RS19070	COG4735	regulation of single-species biofilm formation
HXP40_RS19075	COG1584	GPR1 FUN34 yaaH family protein
HXP40_RS19080	COG0521	Mo-molybdopterin cofactor biosynthetic process
HXP40_RS19085	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HXP40_RS19090	COG1115	amino acid carrier protein
HXP40_RS19105	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HXP40_RS19115	COG0527	aspartate kinase activity
HXP40_RS19115	COG0460	homoserine dehydrogenase
HXP40_RS19125	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HXP40_RS19135	COG0745	RESPONSE REGULATOR receiver
HXP40_RS19140	COG4452	Inner membrane protein CreD
HXP40_RS19145	COG2205	protein histidine kinase activity
HXP40_RS19150	COG0745	RESPONSE REGULATOR receiver
HXP40_RS19155	COG3045	CreA protein
HXP40_RS19160	COG2207	Transcriptional regulator
HXP40_RS19160	COG3708	Transcriptional regulator
HXP40_RS19180	COG0741	lytic transglycosylase activity
HXP40_RS19185	COG0488	(ABC) transporter
HXP40_RS19195	COG3172	ATPase kinase involved in NAD metabolism
HXP40_RS19195	COG1056	cytidyltransferase-related domain
HXP40_RS19200	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HXP40_RS19205	COG0560	Phosphoserine phosphatase
HXP40_RS19210	COG3726	membrane protein affecting hemolysin expression
HXP40_RS19245	COG1328	CTP reductase activity
HXP40_RS19250	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HXP40_RS19255	COG0084	hydrolase, TatD family'
HXP40_RS19260	COG4667	esterase of the alpha-beta hydrolase superfamily
HXP40_RS19270	COG2823	Periplasmic or secreted lipoprotein
HXP40_RS19280	COG1011	Hydrolase
HXP40_RS19285	COG0456	acetyltransferase
HXP40_RS19290	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HXP40_RS19320	COG4114	ferric iron reductase
HXP40_RS19325	COG2197	response regulator
HXP40_RS19330	COG2197	response regulator
HXP40_RS19335	COG2966	Psort location CytoplasmicMembrane, score
HXP40_RS19350	COG1484	DNA-dependent DNA replication
HXP40_RS19365	COG1063	alcohol dehydrogenase
HXP40_RS19370	COG1802	Transcriptional regulator
HXP40_RS19375	COG2271	Major facilitator Superfamily
HXP40_RS19380	COG0840	transmembrane signaling receptor activity
HXP40_RS19385	COG1966	Carbon starvation protein
HXP40_RS19390	COG2879	small protein
HXP40_RS19395	COG0523	cobalamin synthesis protein
HXP40_RS19415	COG2814	Major facilitator Superfamily
HXP40_RS19420	COG2733	membrane
HXP40_RS19425	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HXP40_RS19430	COG1924	4 iron, 4 sulfur cluster binding
HXP40_RS19445	COG0477	Major facilitator Superfamily
HXP40_RS19455	COG3366	ferrous iron transmembrane transporter activity
HXP40_RS19460	COG0700	Nucleoside recognition
HXP40_RS19465	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HXP40_RS19470	COG0583	DNA-binding transcription factor activity
HXP40_RS19490	COG2186	Transcriptional regulator
HXP40_RS19495	COG0246	Mannitol dehydrogenase
HXP40_RS19505	COG2610	gluconate transmembrane transporter activity
HXP40_RS19520	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HXP40_RS19555	COG3436	PFAM IS66 Orf2 family protein
HXP40_RS19560	COG4372	Transposase
HXP40_RS19595	COG1595	DNA-templated transcription, initiation
HXP40_RS19600	COG3712	iron ion homeostasis
HXP40_RS19605	COG4772	TonB-dependent receptor
HXP40_RS19610	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HXP40_RS19615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HXP40_RS19620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HXP40_RS19625	COG1120	ATPase activity
HXP40_RS19630	COG2085	NADP oxidoreductase coenzyme F420-dependent
HXP40_RS19640	COG3344	reverse transcriptase
HXP40_RS19655	COG1309	transcriptional regulator
HXP40_RS19670	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HXP40_RS19685	COG2990	Protein conserved in bacteria
HXP40_RS19690	COG0297	glycogen (starch) synthase activity
HXP40_RS19695	COG0726	polysaccharide deacetylase
HXP40_RS19705	COG3344	reverse transcriptase
HXP40_RS19785	COG0582	viral genome integration into host DNA
HXP40_RS19795	COG1064	alcohol dehydrogenase
HXP40_RS19800	COG0433	COG0433 Predicted ATPase
HXP40_RS19805	COG0795	lipopolysaccharide-transporting ATPase activity
HXP40_RS19810	COG0795	lipopolysaccharide-transporting ATPase activity
HXP40_RS19820	COG2927	DNA polymerase III (CHI subunit)
HXP40_RS19835	COG0456	acetyltransferase
HXP40_RS19840	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
HXP40_RS19855	COG2731	YhcH YjgK YiaL family protein
HXP40_RS19860	COG1309	transcriptional regulator
HXP40_RS19865	COG1028	Short-chain dehydrogenase reductase Sdr
HXP40_RS19870	COG0251	oxidation-reduction process
HXP40_RS19890	COG0251	oxidation-reduction process
HXP40_RS19895	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HXP40_RS19905	COG1609	Transcriptional regulator
HXP40_RS19910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HXP40_RS19910	COG1263	PTS System
HXP40_RS19915	COG0366	Alpha amylase catalytic
HXP40_RS19920	COG1328	CTP reductase activity
HXP40_RS19925	COG0602	queuosine metabolic process
HXP40_RS19930	COG3783	Cytochrome b(562)
HXP40_RS19935	COG0312	modulator of DNA gyrase
HXP40_RS19945	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HXP40_RS19955	COG1172	Belongs to the binding-protein-dependent transport system permease family
HXP40_RS19960	COG1172	Belongs to the binding-protein-dependent transport system permease family
HXP40_RS19965	COG1129	ABC transporter
HXP40_RS19970	COG1879	ABC-type sugar transport system periplasmic component
HXP40_RS19975	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HXP40_RS19980	COG2337	Toxic component of a toxin-antitoxin (TA) module
HXP40_RS19985	COG2336	PFAM SpoVT AbrB
HXP40_RS19990	COG2105	PFAM AIG2 family protein
HXP40_RS19995	COG2911	Protein conserved in bacteria
HXP40_RS20000	COG0729	surface antigen
HXP40_RS20010	COG1253	flavin adenine dinucleotide binding
HXP40_RS20020	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HXP40_RS20030	COG1218	3'(2'),5'-bisphosphate nucleotidase
HXP40_RS20035	COG0737	Belongs to the 5'-nucleotidase family
HXP40_RS20040	COG1733	regulation of RNA biosynthetic process
HXP40_RS20045	COG0702	epimerase
HXP40_RS20050	COG0697	spore germination
HXP40_RS20060	COG1113	amino acid transport
HXP40_RS20065	COG0545	Peptidyl-prolyl cis-trans isomerase
HXP40_RS20070	COG3061	Opacity-associated protein A
HXP40_RS20080	COG0675	Transposase, IS605 OrfB family
HXP40_RS20100	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HXP40_RS20120	COG3477	response to acidic pH
HXP40_RS20125	COG0235	Class ii aldolase
HXP40_RS20140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HXP40_RS20145	COG3414	Phosphotransferase system galactitol-specific IIB component
HXP40_RS20165	COG1073	alpha beta
HXP40_RS20170	COG3650	response to hydrogen peroxide
HXP40_RS20180	COG1960	acyl-CoA dehydrogenase activity
HXP40_RS20185	COG0754	glutathionylspermidine amidase activity
HXP40_RS20190	COG5463	Belongs to the UPF0441 family
HXP40_RS20195	COG3766	membrane
HXP40_RS20215	COG2721	sulfolactate sulfo-lyase activity
HXP40_RS20220	COG2271	Major facilitator Superfamily
HXP40_RS20225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HXP40_RS20230	COG1414	Transcriptional regulator
HXP40_RS20235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HXP40_RS20240	COG0557	exoribonuclease II activity
HXP40_RS20255	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HXP40_RS20260	COG0330	HflC and HflK could
HXP40_RS20265	COG0330	HflC and HflK could
HXP40_RS20270	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HXP40_RS20290	COG0860	N-Acetylmuramoyl-L-alanine amidase
HXP40_RS20295	COG0802	atpase or kinase
HXP40_RS20300	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HXP40_RS20300	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HXP40_RS20305	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HXP40_RS20345	COG1511	domain protein
HXP40_RS20345	COG3264	Mechanosensitive ion channel
HXP40_RS20360	COG0531	amino acid
HXP40_RS20370	COG1053	succinate dehydrogenase
HXP40_RS20375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HXP40_RS20390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HXP40_RS20395	COG3040	lipid binding
HXP40_RS20400	COG2076	Multidrug Resistance protein
HXP40_RS20405	COG5510	response to toxic substance
HXP40_RS20410	COG5510	response to toxic substance
HXP40_RS20420	COG1509	lysine 2,3-aminomutase activity
HXP40_RS20445	COG0531	amino acid
HXP40_RS20450	COG3030	protein affecting phage T7 exclusion by the F plasmid
HXP40_RS20455	COG1027	Aspartate ammonia-lyase
HXP40_RS20460	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HXP40_RS20470	COG4232	protein-disulfide reductase activity
HXP40_RS20475	COG1309	transcriptional regulator
HXP40_RS20485	COG3710	Transcriptional regulator
HXP40_RS20490	COG0531	amino acid
HXP40_RS20495	COG1982	Orn Lys Arg decarboxylase major
HXP40_RS20500	COG3104	oligopeptide transport
HXP40_RS20505	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HXP40_RS20520	COG2388	GCN5-related N-acetyl-transferase
HXP40_RS20525	COG3592	Divergent 4Fe-4S mono-cluster
HXP40_RS20530	COG3290	protein histidine kinase activity
HXP40_RS20535	COG4565	transcriptional regulatory protein
HXP40_RS20540	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HXP40_RS20545	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HXP40_RS20545	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HXP40_RS20550	COG3647	Membrane
HXP40_RS20555	COG2211	Major facilitator Superfamily
HXP40_RS20560	COG1486	melibiose metabolic process
HXP40_RS20565	COG2169	Transcriptional regulator
HXP40_RS20570	COG1982	Orn Lys Arg decarboxylase major
HXP40_RS20575	COG2207	Transcriptional regulator
HXP40_RS20580	COG0531	amino acid
HXP40_RS20585	COG2194	sulfuric ester hydrolase activity
HXP40_RS20605	COG0477	Major facilitator Superfamily
HXP40_RS20620	COG2824	Alkylphosphonate utilization operon protein PhnA
HXP40_RS20625	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HXP40_RS20630	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HXP40_RS20635	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HXP40_RS20645	COG2188	Transcriptional regulator
HXP40_RS20650	COG3624	Phosphonate C-P lyase system protein PhnG
HXP40_RS20655	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HXP40_RS20660	COG3626	phosphonate metabolism
HXP40_RS20665	COG3627	carbon phosphorus lyase activity
HXP40_RS20670	COG4107	phosphonate C-P lyase system protein PhnK
HXP40_RS20675	COG4778	phosphonate C-P lyase system protein PhnL
HXP40_RS20680	COG3454	Phosphonate metabolism
HXP40_RS20685	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
HXP40_RS20690	COG0456	acetyltransferase
HXP40_RS20695	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HXP40_RS20705	COG0698	ribose 5-phosphate isomerase
HXP40_RS20710	COG1737	Transcriptional regulator
HXP40_RS20715	COG1879	ABC-type sugar transport system periplasmic component
HXP40_RS20720	COG1129	ABC transporter
HXP40_RS20725	COG1172	Belongs to the binding-protein-dependent transport system permease family
HXP40_RS20730	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HXP40_RS20735	COG1940	carbohydrate kinase activity
HXP40_RS20740	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HXP40_RS20750	COG1566	PFAM secretion protein HlyD family protein
HXP40_RS20755	COG1289	transmembrane transporter activity
HXP40_RS20760	COG1538	Outer membrane efflux protein
HXP40_RS20770	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HXP40_RS20775	COG1301	dicarboxylic acid transport
HXP40_RS20780	COG4235	cytochrome complex assembly
HXP40_RS20785	COG3088	subunit of a heme lyase
HXP40_RS20790	COG1138	Cytochrome C-type biogenesis protein
HXP40_RS20795	COG3301	Polysulphide reductase, NrfD
HXP40_RS20800	COG0437	4 iron, 4 sulfur cluster binding
HXP40_RS20805	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HXP40_RS20815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HXP40_RS20820	COG3162	membrane
HXP40_RS20830	COG1357	PFAM Pentapeptide repeats (8 copies)
HXP40_RS20835	COG0025	NhaP-type Na H and K H
HXP40_RS20840	COG2252	PERMEase
HXP40_RS20845	COG0789	Transcriptional regulator
HXP40_RS20850	COG2207	Transcriptional regulator
HXP40_RS20855	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HXP40_RS20895	COG0629	single-stranded DNA binding
HXP40_RS20900	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HXP40_RS20905	COG2315	Protein conserved in bacteria
HXP40_RS20910	COG0432	Pfam Uncharacterised protein family UPF0047
HXP40_RS20915	COG3700	Belongs to the class B bacterial acid phosphatase family
HXP40_RS20925	COG1448	Aminotransferase
HXP40_RS20930	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HXP40_RS20935	COG0305	Participates in initiation and elongation during chromosome replication
HXP40_RS20940	COG0604	alcohol dehydrogenase
HXP40_RS20950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HXP40_RS20960	COG0735	belongs to the Fur family
HXP40_RS20965	COG3237	CsbD-like
HXP40_RS20970	COG0534	Mate efflux family protein
HXP40_RS20980	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HXP40_RS21015	COG3842	ATPase activity
HXP40_RS21020	COG2182	Extracellular solute-binding protein
HXP40_RS21025	COG1175	transmembrane transport
HXP40_RS21030	COG3833	ABC-type maltose transport systems, permease component
HXP40_RS21035	COG0477	Major facilitator Superfamily
HXP40_RS21035	COG2814	Major facilitator Superfamily
HXP40_RS21055	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HXP40_RS21080	COG0527	aspartate kinase activity
HXP40_RS21090	COG1187	pseudouridine synthase activity
HXP40_RS21100	COG1283	sodium-dependent phosphate transmembrane transporter activity
HXP40_RS21105	COG0646	methionine synthase
HXP40_RS21105	COG1410	methionine synthase
HXP40_RS21110	COG1414	Transcriptional regulator
HXP40_RS21125	COG2224	Isocitrate lyase
HXP40_RS21130	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HXP40_RS21140	COG0456	acetyltransferase
HXP40_RS21175	COG0151	Belongs to the GarS family
HXP40_RS21180	COG2204	response regulator
HXP40_RS21185	COG4191	Histidine kinase
HXP40_RS21190	COG3678	ATP-independent chaperone mediated protein folding
HXP40_RS21205	COG3068	Protein conserved in bacteria
HXP40_RS21240	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HXP40_RS21245	COG2104	thiamine diphosphate biosynthetic process
HXP40_RS21255	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HXP40_RS21295	COG0250	Participates in transcription elongation, termination and antitermination
HXP40_RS21300	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HXP40_RS21335	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HXP40_RS21335	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HXP40_RS21340	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HXP40_RS21370	COG4206	TonB-dependent receptor
HXP40_RS21385	COG1309	transcriptional regulator
HXP40_RS21395	COG0583	DNA-binding transcription factor activity
HXP40_RS21410	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HXP40_RS21425	COG2194	sulfuric ester hydrolase activity
HXP40_RS21430	COG2207	Transcriptional regulator
HXP40_RS21435	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HXP40_RS21440	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HXP40_RS21445	COG1882	Formate acetyltransferase
HXP40_RS21450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HXP40_RS21455	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HXP40_RS21460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HXP40_RS21460	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HXP40_RS21460	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HXP40_RS21465	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HXP40_RS21470	COG0371	Dehydrogenase
HXP40_RS21475	COG3738	Protein conserved in bacteria
HXP40_RS21480	COG0697	spore germination
HXP40_RS21490	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HXP40_RS21495	COG0527	aspartate kinase activity
HXP40_RS21495	COG0460	homoserine dehydrogenase
HXP40_RS21500	COG0626	cystathionine gamma-synthase activity
HXP40_RS21510	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HXP40_RS21520	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HXP40_RS21525	COG1609	Transcriptional regulator
HXP40_RS21530	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HXP40_RS21545	COG1575	Belongs to the MenA family. Type 1 subfamily
HXP40_RS21560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HXP40_RS21570	COG1494	fructose-1,6-bisphosphatase
HXP40_RS21575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HXP40_RS21580	COG0589	response to stress
HXP40_RS21585	COG3691	Protein conserved in bacteria
HXP40_RS21590	COG3152	Membrane
HXP40_RS21610	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HXP40_RS21675	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HXP40_RS21680	COG4372	Transposase
HXP40_RS21685	COG3436	PFAM IS66 Orf2 family protein
HXP40_RS21695	COG1484	DNA-dependent DNA replication
HXP40_RS21700	COG4584	PFAM Integrase catalytic
HXP40_RS21745	COG4974	Belongs to the 'phage' integrase family
HXP40_RS21750	COG3678	ATP-independent chaperone mediated protein folding
HXP40_RS21755	COG0745	RESPONSE REGULATOR receiver
HXP40_RS21760	COG2205	protein histidine kinase activity
HXP40_RS21765	COG2258	MOSC domain
HXP40_RS21775	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HXP40_RS21815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HXP40_RS21820	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HXP40_RS21820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HXP40_RS21825	COG1363	Peptidase, m42
HXP40_RS21830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HXP40_RS21830	COG3711	transcriptional antiterminator
HXP40_RS21850	COG0437	4 iron, 4 sulfur cluster binding
HXP40_RS21855	COG2864	formate dehydrogenase
HXP40_RS21865	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HXP40_RS21870	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HXP40_RS21875	COG0456	acetyltransferase
HXP40_RS21890	COG1011	Hydrolase
HXP40_RS21895	COG1349	DNA-binding transcription factor activity
HXP40_RS21900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HXP40_RS21905	COG2084	Dehydrogenase
HXP40_RS21910	COG3684	Belongs to the aldolase LacD family
HXP40_RS21915	COG2942	2-epimerase
HXP40_RS21920	COG2017	converts alpha-aldose to the beta-anomer
HXP40_RS21925	COG1501	Belongs to the glycosyl hydrolase 31 family
HXP40_RS21930	COG2211	Major facilitator Superfamily
HXP40_RS21935	COG2211	Major facilitator Superfamily
HXP40_RS21940	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HXP40_RS21945	COG2271	Major facilitator Superfamily
HXP40_RS21950	COG1082	Xylose isomerase domain protein TIM barrel
HXP40_RS21955	COG2188	Transcriptional regulator
HXP40_RS21960	COG1217	gtp-binding protein TYPA
HXP40_RS21965	COG0174	glutamine synthetase
HXP40_RS21970	COG3852	Histidine kinase
HXP40_RS21975	COG2204	response regulator
HXP40_RS21985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HXP40_RS22000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HXP40_RS22000	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HXP40_RS22005	COG0204	Acyl-transferase
HXP40_RS22010	COG5339	Protein conserved in bacteria
HXP40_RS22015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HXP40_RS22020	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HXP40_RS22025	COG3084	Protein conserved in bacteria
HXP40_RS22030	COG0746	molybdenum cofactor guanylyltransferase activity
HXP40_RS22035	COG1763	Mo-molybdopterin cofactor biosynthetic process
HXP40_RS22065	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HXP40_RS22070	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HXP40_RS22075	COG1739	Uncharacterized protein family UPF0029
HXP40_RS22090	COG0183	Belongs to the thiolase family
HXP40_RS22095	COG0543	2 iron, 2 sulfur cluster binding
HXP40_RS22100	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HXP40_RS22105	COG0250	Participates in transcription elongation, termination and antitermination
HXP40_RS22110	COG0084	hydrolase, TatD family'
HXP40_RS22115	COG0805	protein transport
HXP40_RS22120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HXP40_RS22125	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HXP40_RS22135	COG3165	ubiquinone biosynthetic process from chorismate
HXP40_RS22145	COG1322	Protein conserved in bacteria
HXP40_RS22150	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HXP40_RS22155	COG0412	Dienelactone hydrolase
HXP40_RS22165	COG0583	DNA-binding transcription factor activity
HXP40_RS22170	COG0697	spore germination
HXP40_RS22175	COG0561	phosphatase activity
HXP40_RS22180	COG2267	carboxylic ester hydrolase activity
HXP40_RS22185	COG1280	lysine exporter protein (LysE YggA)
HXP40_RS22190	COG1280	lysine exporter protein (LysE YggA)
HXP40_RS22195	COG0514	ATP-dependent DNA helicase (RecQ)
HXP40_RS22200	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
HXP40_RS22205	COG2050	protein possibly involved in aromatic compounds catabolism
HXP40_RS22210	COG2962	Rard protein
HXP40_RS22225	COG0598	Magnesium transport protein CorA
HXP40_RS22230	COG3698	Phosphodiester glycosidase
HXP40_RS22235	COG0210	DNA helicase
HXP40_RS22240	COG1011	Hydrolase
HXP40_RS22250	COG3159	Protein conserved in bacteria
HXP40_RS22260	COG5567	small periplasmic lipoprotein
HXP40_RS22270	COG3072	Adenylate cyclase
HXP40_RS22280	COG1587	Uroporphyrinogen-III synthase
HXP40_RS22285	COG2959	enzyme of heme biosynthesis
HXP40_RS22290	COG3071	HemY protein
HXP40_RS22295	COG3119	arylsulfatase activity
HXP40_RS22300	COG0641	radical SAM
HXP40_RS22325	COG1113	amino acid transport
HXP40_RS22345	COG2244	polysaccharide biosynthetic process
HXP40_RS22350	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HXP40_RS22355	COG0456	acetyltransferase
HXP40_RS22360	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HXP40_RS22365	COG1088	dTDP-glucose 4,6-dehydratase activity
HXP40_RS22370	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HXP40_RS22375	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HXP40_RS22380	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HXP40_RS22385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HXP40_RS22390	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HXP40_RS22400	COG3118	belongs to the thioredoxin family
HXP40_RS22415	COG0210	DNA helicase
HXP40_RS22425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HXP40_RS22435	COG0583	DNA-binding transcription factor activity
HXP40_RS22440	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HXP40_RS22450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HXP40_RS22455	COG3978	acetolactate synthase activity
HXP40_RS22475	COG0606	chelatase, subunit chli
HXP40_RS22480	COG3085	chromosome segregation
HXP40_RS22520	COG2186	Transcriptional regulator
HXP40_RS22525	COG0477	Major facilitator Superfamily
HXP40_RS22530	COG1609	Transcriptional regulator
HXP40_RS22535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HXP40_RS22540	COG1879	ABC-type sugar transport system periplasmic component
HXP40_RS22545	COG1172	Belongs to the binding-protein-dependent transport system permease family
HXP40_RS22550	COG1129	ABC transporter
HXP40_RS22580	COG1522	sequence-specific DNA binding
HXP40_RS22585	COG0716	FMN binding
HXP40_RS22600	COG3312	ion transport
HXP40_RS22650	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HXP40_RS22655	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HXP40_RS22660	COG0573	inorganic phosphate transmembrane transporter activity
HXP40_RS22665	COG0581	inorganic phosphate transmembrane transporter activity
HXP40_RS22670	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HXP40_RS22675	COG0704	Plays a role in the regulation of phosphate uptake
HXP40_RS22680	COG3711	transcriptional antiterminator
HXP40_RS22685	COG2190	(PTS) system
HXP40_RS22685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HXP40_RS22685	COG1263	PTS System
HXP40_RS22690	COG2723	6-phospho-beta-galactosidase activity
HXP40_RS22700	COG2382	esterase
HXP40_RS22705	COG0363	glucosamine-6-phosphate deaminase activity
HXP40_RS22720	COG3436	PFAM IS66 Orf2 family protein
HXP40_RS22725	COG4372	Transposase
HXP40_RS22740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HXP40_RS22745	COG2252	PERMEase
HXP40_RS22750	COG0431	NADPH-dependent FMN reductase
HXP40_RS22755	COG2091	lysine biosynthetic process via aminoadipic acid
HXP40_RS22770	COG0814	amino acid
HXP40_RS22830	COG3344	reverse transcriptase
HXP40_RS22895	COG2382	esterase
HXP40_RS22900	COG2819	hydrolase of the alpha beta superfamily
HXP40_RS22915	COG3385	transposase activity
HXP40_RS22960	COG5290	Psort location Cytoplasmic, score
HXP40_RS23005	COG0697	spore germination
HXP40_RS23075	COG0673	inositol 2-dehydrogenase activity
HXP40_RS23405	COG4584	PFAM Integrase catalytic
HXP40_RS23410	COG1484	DNA-dependent DNA replication
HXP40_RS23465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HXP40_RS23480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HXP40_RS23485	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HXP40_RS23490	COG1121	(ABC) transporter
HXP40_RS24015	COG1196	nuclear chromosome segregation
HXP40_RS24025	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
HXP40_RS24035	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities