locus-tag	class	description
ASE18_RS00020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASE18_RS00025	COG4651	solute:proton antiporter activity
ASE18_RS00025	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ASE18_RS00030	COG2223	nitrite transmembrane transporter activity
ASE18_RS00035	COG0737	Belongs to the 5'-nucleotidase family
ASE18_RS00040	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ASE18_RS00045	COG3735	TraB family
ASE18_RS00050	COG3093	addiction module antidote protein HigA
ASE18_RS00055	COG2217	Heavy metal translocating P-type atpase
ASE18_RS00060	COG2066	Belongs to the glutaminase family
ASE18_RS00065	COG0531	amino acid
ASE18_RS00070	COG0789	Transcriptional regulator
ASE18_RS00075	COG1585	Membrane protein implicated in regulation of membrane protease activity
ASE18_RS00080	COG0330	HflC and HflK could
ASE18_RS00085	COG4619	ABC transporter
ASE18_RS00090	COG0390	transport system, permease component
ASE18_RS00095	COG3118	belongs to the thioredoxin family
ASE18_RS00100	COG0300	oxidoreductase activity
ASE18_RS00105	COG2755	lipolytic protein G-D-S-L family
ASE18_RS00110	COG4181	ATPase activity
ASE18_RS00115	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ASE18_RS00125	COG0583	DNA-binding transcription factor activity
ASE18_RS00135	COG1414	Transcriptional regulator
ASE18_RS00140	COG3960	tartronate-semialdehyde synthase activity
ASE18_RS00145	COG3622	Belongs to the hyi family
ASE18_RS00150	COG2084	Dehydrogenase
ASE18_RS00155	COG1953	Uracil, thiamine, allantoin
ASE18_RS00165	COG2233	PERMEase
ASE18_RS00170	COG1929	Belongs to the glycerate kinase type-1 family
ASE18_RS00175	COG3257	ureidoglycine aminohydrolase activity
ASE18_RS00180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASE18_RS00185	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ASE18_RS00190	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ASE18_RS00195	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ASE18_RS00205	COG0549	Belongs to the carbamate kinase family
ASE18_RS00210	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ASE18_RS00215	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ASE18_RS00225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ASE18_RS00235	COG1988	membrane-bound metal-dependent
ASE18_RS00240	COG2501	S4 domain
ASE18_RS00250	COG3539	Fimbrial protein
ASE18_RS00255	COG3121	Chaperone
ASE18_RS00260	COG3188	usher protein
ASE18_RS00265	COG3539	Fimbrial protein
ASE18_RS00270	COG3539	Fimbrial protein
ASE18_RS00275	COG2197	response regulator
ASE18_RS00285	COG2207	Transcriptional regulator
ASE18_RS00295	COG4783	chaperone-mediated protein folding
ASE18_RS00305	COG5433	transposase activity
ASE18_RS00320	COG3209	COG3209 Rhs family protein
ASE18_RS00320	COG4104	PAAR repeat-containing protein
ASE18_RS00330	COG5002	protein histidine kinase activity
ASE18_RS00335	COG0745	RESPONSE REGULATOR receiver
ASE18_RS00340	COG1538	Outer membrane efflux protein
ASE18_RS00345	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASE18_RS00350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASE18_RS00355	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASE18_RS00360	COG1113	amino acid transport
ASE18_RS00365	COG0668	transmembrane transport
ASE18_RS00370	COG0778	Nitroreductase
ASE18_RS00375	COG2315	Protein conserved in bacteria
ASE18_RS00400	COG2977	Belongs to the P-Pant transferase superfamily
ASE18_RS00405	COG4771	TonB-dependent receptor
ASE18_RS00410	COG2382	esterase
ASE18_RS00415	COG3251	PFAM MbtH domain protein
ASE18_RS00420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ASE18_RS00420	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ASE18_RS00425	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ASE18_RS00430	COG1120	ATPase activity
ASE18_RS00435	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASE18_RS00440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASE18_RS00450	COG4592	Periplasmic binding protein
ASE18_RS00455	COG1169	isochorismate synthase
ASE18_RS00460	COG1021	2,3-dihydroxybenzoate-AMP ligase
ASE18_RS00465	COG1535	isochorismatase
ASE18_RS00465	COG3433	isochorismatase activity
ASE18_RS00470	COG1028	Short-chain dehydrogenase reductase Sdr
ASE18_RS00475	COG2050	protein possibly involved in aromatic compounds catabolism
ASE18_RS00480	COG1966	Carbon starvation protein
ASE18_RS00485	COG2879	small protein
ASE18_RS00490	COG0371	Dehydrogenase
ASE18_RS00495	COG0436	Aminotransferase
ASE18_RS00500	COG1475	DNA binding
ASE18_RS00505	COG3969	phosphoadenosine phosphosulfate
ASE18_RS00510	COG0583	DNA-binding transcription factor activity
ASE18_RS00530	COG0583	DNA-binding transcription factor activity
ASE18_RS00535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASE18_RS00540	COG0450	alkyl hydroperoxide reductase
ASE18_RS00545	COG3634	alkyl hydroperoxide reductase activity
ASE18_RS00550	COG0589	response to stress
ASE18_RS00555	COG1063	alcohol dehydrogenase
ASE18_RS00565	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASE18_RS00570	COG3719	Belongs to the RNase T2 family
ASE18_RS00575	COG0471	metal ion transport
ASE18_RS00590	COG3051	citrate lyase alpha subunit
ASE18_RS00595	COG2301	Belongs to the HpcH HpaI aldolase family
ASE18_RS00605	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ASE18_RS00610	COG3290	protein histidine kinase activity
ASE18_RS00615	COG4565	transcriptional regulatory protein
ASE18_RS00620	COG3069	C4-dicarboxylate transmembrane transporter activity
ASE18_RS00640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASE18_RS00645	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASE18_RS00655	COG0583	DNA-binding transcription factor activity
ASE18_RS00675	COG1686	Belongs to the peptidase S11 family
ASE18_RS00680	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ASE18_RS00685	COG0772	Belongs to the SEDS family
ASE18_RS00690	COG0768	penicillin binding
ASE18_RS00700	COG0799	negative regulation of ribosome biogenesis
ASE18_RS00705	COG0406	alpha-ribazole phosphatase activity
ASE18_RS00715	COG1466	dna polymerase III delta subunit
ASE18_RS00730	COG2888	peptidyl-tyrosine sulfation
ASE18_RS00735	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ASE18_RS00745	COG2214	Heat shock protein DnaJ domain protein
ASE18_RS00750	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ASE18_RS00760	COG2214	Heat shock protein DnaJ domain protein
ASE18_RS00780	COG1126	abc transporter atp-binding protein
ASE18_RS00785	COG0765	amino acid transport
ASE18_RS00790	COG0765	amino acid transport
ASE18_RS00795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASE18_RS00805	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ASE18_RS00810	COG4535	Mg2 and Co2 transporter CorC
ASE18_RS00820	COG1702	phosphate starvation-inducible protein PhoH
ASE18_RS00830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASE18_RS00870	COG0367	asparagine synthase
ASE18_RS00880	COG0647	UMP catabolic process
ASE18_RS00885	COG1940	carbohydrate kinase activity
ASE18_RS00885	COG1846	Transcriptional regulator
ASE18_RS00890	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ASE18_RS00900	COG2190	(PTS) system
ASE18_RS00900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASE18_RS00900	COG1263	PTS System
ASE18_RS00920	COG0735	belongs to the Fur family
ASE18_RS00935	COG0716	FMN binding
ASE18_RS00945	COG0596	Alpha beta hydrolase
ASE18_RS00950	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ASE18_RS00955	COG0033	Phosphoglucomutase
ASE18_RS00960	COG0531	amino acid
ASE18_RS00965	COG1982	Orn Lys Arg decarboxylase major
ASE18_RS00975	COG0745	RESPONSE REGULATOR receiver
ASE18_RS00980	COG2205	protein histidine kinase activity
ASE18_RS01010	COG3209	COG3209 Rhs family protein
ASE18_RS01020	COG3209	COG3209 Rhs family protein
ASE18_RS01030	COG5433	transposase activity
ASE18_RS01040	COG3272	Protein of unknown function (DUF1722)
ASE18_RS01045	COG0415	Belongs to the DNA photolyase family
ASE18_RS01055	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ASE18_RS01060	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ASE18_RS01065	COG1984	allophanate hydrolase subunit 2
ASE18_RS01080	COG3180	Ammonia monooxygenase
ASE18_RS01085	COG3539	Fimbrial protein
ASE18_RS01095	COG3539	Fimbrial protein
ASE18_RS01100	COG3121	Chaperone
ASE18_RS01105	COG3188	usher protein
ASE18_RS01110	COG3539	Fimbrial protein
ASE18_RS01115	COG0372	Belongs to the citrate synthase family
ASE18_RS01125	COG2009	succinate dehydrogenase
ASE18_RS01130	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ASE18_RS01135	COG1053	succinate dehydrogenase
ASE18_RS01140	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ASE18_RS01150	COG0567	Dehydrogenase, E1 component
ASE18_RS01155	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASE18_RS01165	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ASE18_RS01170	COG2188	Transcriptional regulator
ASE18_RS01175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASE18_RS01175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASE18_RS01175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASE18_RS01180	COG0383	alpha-mannosidase activity
ASE18_RS01190	COG1271	oxidase subunit
ASE18_RS01195	COG1294	oxidase, subunit
ASE18_RS01200	COG4890	Cyd operon protein YbgT
ASE18_RS01205	COG3790	cyd operon protein YbgE
ASE18_RS01210	COG0824	Thioesterase
ASE18_RS01215	COG0811	peptide transport
ASE18_RS01220	COG0848	biopolymer transport protein
ASE18_RS01225	COG3064	Membrane
ASE18_RS01235	COG2885	chlorophyll binding
ASE18_RS01240	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ASE18_RS01285	COG3201	nicotinamide mononucleotide transporter
ASE18_RS01290	COG1230	cation diffusion facilitator family transporter
ASE18_RS01305	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASE18_RS01315	COG2017	converts alpha-aldose to the beta-anomer
ASE18_RS01325	COG1085	galactose-1-phosphate uridylyltransferase
ASE18_RS01330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ASE18_RS01335	COG1119	ATPase activity
ASE18_RS01340	COG3585	molybdate ion transport
ASE18_RS01340	COG2005	Transcriptional regulator
ASE18_RS01350	COG0725	ABC transporter, periplasmic molybdate-binding protein
ASE18_RS01355	COG4149	molybdate abc transporter
ASE18_RS01360	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ASE18_RS01365	COG0561	phosphatase activity
ASE18_RS01375	COG0583	DNA-binding transcription factor activity
ASE18_RS01380	COG2828	Protein conserved in bacteria
ASE18_RS01385	COG0471	metal ion transport
ASE18_RS01390	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ASE18_RS01395	COG4677	pectinesterase activity
ASE18_RS01400	COG0582	viral genome integration into host DNA
ASE18_RS01550	COG3272	Protein of unknown function (DUF1722)
ASE18_RS01565	COG3772	lysozyme
ASE18_RS01585	COG5562	phage envelope protein
ASE18_RS01605	COG4220	transposase activity
ASE18_RS01615	COG0500	methyltransferase
ASE18_RS01625	COG2199	diguanylate cyclase activity
ASE18_RS01630	COG1662	PFAM IS1 transposase
ASE18_RS01630	COG3677	Transposase
ASE18_RS01635	COG1662	PFAM IS1 transposase
ASE18_RS01640	COG1881	PFAM PEBP family protein
ASE18_RS01645	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ASE18_RS01660	COG2226	methyltransferase
ASE18_RS01665	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ASE18_RS01675	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ASE18_RS01690	COG0521	Mo-molybdopterin cofactor biosynthetic process
ASE18_RS01700	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ASE18_RS01705	COG0314	molybdopterin synthase activity
ASE18_RS01710	COG0670	Belongs to the BI1 family
ASE18_RS01730	COG0670	Belongs to the BI1 family
ASE18_RS01735	COG0392	lysyltransferase activity
ASE18_RS01740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASE18_RS01745	COG3568	Endonuclease Exonuclease Phosphatase
ASE18_RS01755	COG0842	Transport permease protein
ASE18_RS01760	COG0842	Transport permease protein
ASE18_RS01765	COG1131	(ABC) transporter
ASE18_RS01775	COG1309	transcriptional regulator
ASE18_RS01780	COG0513	Belongs to the DEAD box helicase family
ASE18_RS01785	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
ASE18_RS01790	COG1199	ATP-dependent helicase activity
ASE18_RS01795	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASE18_RS01800	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ASE18_RS01810	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ASE18_RS01820	COG4774	siderophore transport
ASE18_RS01835	COG0668	transmembrane transport
ASE18_RS01840	COG1126	abc transporter atp-binding protein
ASE18_RS01845	COG0765	amino acid transport
ASE18_RS01850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASE18_RS01865	COG5006	permease, DMT superfamily
ASE18_RS01875	COG2801	Transposase and inactivated derivatives
ASE18_RS01880	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ASE18_RS01885	COG2194	sulfuric ester hydrolase activity
ASE18_RS01895	COG1321	iron dependent repressor
ASE18_RS01900	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ASE18_RS01905	COG1376	ErfK ybiS ycfS ynhG family protein
ASE18_RS01910	COG0488	(ABC) transporter
ASE18_RS01920	COG0561	phosphatase activity
ASE18_RS01925	COG1882	Formate acetyltransferase
ASE18_RS01930	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ASE18_RS01935	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ASE18_RS01940	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ASE18_RS01945	COG0303	'Molybdopterin
ASE18_RS01950	COG1446	asparaginase
ASE18_RS01975	COG2200	EAL domain
ASE18_RS01980	COG2199	diguanylate cyclase activity
ASE18_RS01995	COG2133	pyrroloquinoline quinone binding
ASE18_RS02000	COG0625	glutathione transferase activity
ASE18_RS02005	COG1686	Belongs to the peptidase S11 family
ASE18_RS02010	COG1349	DNA-binding transcription factor activity
ASE18_RS02015	COG0671	phosphoesterase, PA-phosphatase related
ASE18_RS02020	COG2814	Major facilitator Superfamily
ASE18_RS02030	COG0561	phosphatase activity
ASE18_RS02035	COG0738	Major facilitator superfamily
ASE18_RS02040	COG3226	Transcriptional regulator
ASE18_RS02045	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ASE18_RS02080	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ASE18_RS02110	COG4695	Portal protein
ASE18_RS02135	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ASE18_RS02145	COG0778	Nitroreductase
ASE18_RS02165	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ASE18_RS02170	COG3842	ATPase activity
ASE18_RS02175	COG1176	ABC-type spermidine putrescine transport system, permease component I
ASE18_RS02180	COG1177	transmembrane transport
ASE18_RS02195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASE18_RS02200	COG4160	amino acid transport
ASE18_RS02205	COG4215	(ABC) transporter
ASE18_RS02210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASE18_RS02215	COG1126	abc transporter atp-binding protein
ASE18_RS02230	COG3023	N-Acetylmuramoyl-L-alanine amidase
ASE18_RS02235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASE18_RS02240	COG0702	epimerase
ASE18_RS02245	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ASE18_RS02250	COG0028	Belongs to the TPP enzyme family
ASE18_RS02255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASE18_RS02265	COG2431	L-lysine efflux transmembrane transporter activity
ASE18_RS02280	COG3593	DNA synthesis involved in DNA repair
ASE18_RS02285	COG2990	Protein conserved in bacteria
ASE18_RS02290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASE18_RS02295	COG0577	efflux transmembrane transporter activity
ASE18_RS02295	COG1136	(ABC) transporter
ASE18_RS02300	COG1278	Cold shock
ASE18_RS02310	COG0542	response to heat
ASE18_RS02330	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ASE18_RS02335	COG4988	ABC transporter
ASE18_RS02340	COG0492	ferredoxin-NADP+ reductase activity
ASE18_RS02345	COG1522	sequence-specific DNA binding
ASE18_RS02360	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ASE18_RS02370	COG0243	molybdopterin cofactor binding
ASE18_RS02375	COG0437	4 iron, 4 sulfur cluster binding
ASE18_RS02380	COG3302	dmso reductase anchor subunit
ASE18_RS02385	COG1335	isochorismatase
ASE18_RS02395	COG0531	amino acid
ASE18_RS02400	COG0583	DNA-binding transcription factor activity
ASE18_RS02405	COG2249	NAD(P)H dehydrogenase (quinone) activity
ASE18_RS02410	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ASE18_RS02415	COG1882	Formate acetyltransferase
ASE18_RS02420	COG2116	formate transmembrane transporter activity
ASE18_RS02425	COG1944	ATP diphosphatase activity
ASE18_RS02430	COG2323	membrane
ASE18_RS02445	COG0501	Belongs to the peptidase M48B family
ASE18_RS02455	COG0539	negative regulation of cytoplasmic translation
ASE18_RS02465	COG2333	competence protein COMEC
ASE18_RS02465	COG0658	competence protein
ASE18_RS02470	COG1132	(ABC) transporter
ASE18_RS02480	COG3214	Protein conserved in bacteria
ASE18_RS02495	COG3173	Aminoglycoside phosphotransferase
ASE18_RS02500	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ASE18_RS02505	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASE18_RS02515	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ASE18_RS02525	COG2989	Protein conserved in bacteria
ASE18_RS02530	COG3108	Peptidase M15
ASE18_RS02535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASE18_RS02540	COG1448	Aminotransferase
ASE18_RS02565	COG0308	aminopeptidase N
ASE18_RS02575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASE18_RS02585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ASE18_RS02590	COG0431	NADPH-dependent FMN reductase
ASE18_RS02595	COG3539	Fimbrial protein
ASE18_RS02600	COG3121	Chaperone
ASE18_RS02605	COG3188	usher protein
ASE18_RS02610	COG3539	Fimbrial protein
ASE18_RS02615	COG3539	Fimbrial protein
ASE18_RS02620	COG3539	Fimbrial protein
ASE18_RS02625	COG3121	Chaperone
ASE18_RS02640	COG3217	Mosc domain protein beta barrel domain protein
ASE18_RS02640	COG0633	Ferredoxin
ASE18_RS02650	COG0488	(ABC) transporter
ASE18_RS02655	COG2995	paraquat-inducible protein a
ASE18_RS02660	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ASE18_RS02660	COG3008	intermembrane lipid transfer
ASE18_RS02665	COG3009	Protein conserved in bacteria
ASE18_RS02670	COG3130	regulation of translation
ASE18_RS02680	COG1067	ATP-dependent peptidase activity
ASE18_RS02705	COG3070	regulator of competence-specific genes
ASE18_RS02710	COG1289	transmembrane transporter activity
ASE18_RS02715	COG3304	Inner membrane component domain
ASE18_RS02720	COG0210	DNA helicase
ASE18_RS02740	COG1832	CoA-binding protein
ASE18_RS02755	COG1254	Belongs to the acylphosphatase family
ASE18_RS02760	COG2920	part of a sulfur-relay system
ASE18_RS02765	COG0670	Belongs to the BI1 family
ASE18_RS02775	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ASE18_RS02780	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ASE18_RS02785	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
ASE18_RS02790	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ASE18_RS02795	COG1999	signal sequence binding
ASE18_RS02800	COG1773	rubredoxin
ASE18_RS02805	COG1271	oxidase subunit
ASE18_RS02810	COG1294	oxidase, subunit
ASE18_RS02825	COG0489	protein tyrosine kinase activity
ASE18_RS02825	COG3206	protein involved in exopolysaccharide biosynthesis
ASE18_RS02830	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASE18_RS02835	COG1596	polysaccharide export
ASE18_RS02840	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASE18_RS02860	COG1278	Cold shock
ASE18_RS02865	COG1278	Cold shock
ASE18_RS02880	COG0348	domain, Protein
ASE18_RS02885	COG2205	protein histidine kinase activity
ASE18_RS02885	COG0784	Response regulator, receiver
ASE18_RS02885	COG2198	Histidine kinase
ASE18_RS02890	COG1879	ABC-type sugar transport system periplasmic component
ASE18_RS02895	COG0745	RESPONSE REGULATOR receiver
ASE18_RS02900	COG3005	denitrification pathway
ASE18_RS02905	COG0243	molybdopterin cofactor binding
ASE18_RS02945	COG1662	PFAM IS1 transposase
ASE18_RS02955	COG3729	General stress protein
ASE18_RS02960	COG2233	PERMEase
ASE18_RS02995	COG1309	transcriptional regulator
ASE18_RS03000	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ASE18_RS03000	COG0506	proline dehydrogenase activity
ASE18_RS03000	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ASE18_RS03010	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASE18_RS03025	COG2822	iron ion transport
ASE18_RS03040	COG1702	phosphate starvation-inducible protein PhoH
ASE18_RS03045	COG3658	cytochrome
ASE18_RS03050	COG1215	transferase activity, transferring glycosyl groups
ASE18_RS03055	COG1649	PFAM Uncharacterised BCR, COG1649
ASE18_RS03055	COG0726	polysaccharide deacetylase
ASE18_RS03060	COG0457	Tetratricopeptide repeat
ASE18_RS03065	COG3706	GGDEF domain
ASE18_RS03070	COG2801	Transposase and inactivated derivatives
ASE18_RS03095	COG0582	viral genome integration into host DNA
ASE18_RS03125	COG3436	PFAM IS66 Orf2 family protein
ASE18_RS03185	COG1216	Glycosyl transferase, family 2
ASE18_RS03200	COG2801	Transposase and inactivated derivatives
ASE18_RS03215	COG3039	Transposase
ASE18_RS03245	COG1216	Glycosyl transferase, family 2
ASE18_RS03265	COG3468	outer membrane autotransporter barrel domain protein
ASE18_RS03280	COG2003	Belongs to the UPF0758 family
ASE18_RS03335	COG3381	protein complex oligomerization
ASE18_RS03345	COG1462	curli production assembly transport component CsgG
ASE18_RS03360	COG2197	response regulator
ASE18_RS03390	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ASE18_RS03395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASE18_RS03420	COG2943	transferase activity, transferring hexosyl groups
ASE18_RS03425	COG5645	(Lipo)protein
ASE18_RS03445	COG1560	Kdo2-lipid A biosynthetic process
ASE18_RS03455	COG2353	YceI-like domain
ASE18_RS03460	COG3038	cytochrome b561
ASE18_RS03495	COG2999	glutathione oxidoreductase activity
ASE18_RS03505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASE18_RS03515	COG0673	inositol 2-dehydrogenase activity
ASE18_RS03520	COG0728	peptidoglycan biosynthetic process
ASE18_RS03525	COG3418	PFAM FlgN family protein
ASE18_RS03530	COG2747	anti-sigma28 factor FlgM
ASE18_RS03535	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
ASE18_RS03540	COG1815	bacterial-type flagellum-dependent cell motility
ASE18_RS03545	COG1558	bacterial-type flagellum-dependent cell motility
ASE18_RS03550	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ASE18_RS03555	COG1749	Flagellar hook protein flgE
ASE18_RS03560	COG4787	bacterial-type flagellum-dependent cell motility
ASE18_RS03565	COG4786	Flagellar basal body rod
ASE18_RS03580	COG3951	Flagellar rod assembly protein muramidase FlgJ
ASE18_RS03580	COG1705	Flagellar rod assembly protein muramidase FlgJ
ASE18_RS03585	COG1256	bacterial-type flagellum assembly
ASE18_RS03590	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASE18_RS03595	COG1530	ribonuclease E activity
ASE18_RS03605	COG0564	pseudouridine synthase activity
ASE18_RS03610	COG0424	maF-like protein
ASE18_RS03615	COG1399	metal-binding, possibly nucleic acid-binding protein
ASE18_RS03635	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ASE18_RS03640	COG1028	Short-chain dehydrogenase reductase Sdr
ASE18_RS03650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASE18_RS03655	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASE18_RS03660	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ASE18_RS03670	COG0470	DNA polymerase III
ASE18_RS03675	COG0084	hydrolase, TatD family'
ASE18_RS03680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASE18_RS03680	COG1263	PTS System
ASE18_RS03685	COG4773	Receptor
ASE18_RS03690	COG0537	adenosine 5'-monophosphoramidase activity
ASE18_RS03695	COG5633	Lipoprotein
ASE18_RS03700	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
ASE18_RS03720	COG1252	NADH dehydrogenase
ASE18_RS03725	COG3134	Outer membrane lipoprotein
ASE18_RS03730	COG1309	transcriptional regulator
ASE18_RS03740	COG1376	ErfK ybiS ycfS ynhG family protein
ASE18_RS03740	COG1388	LysM domain
ASE18_RS03745	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ASE18_RS03750	COG4763	Acyl-transferase
ASE18_RS03755	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASE18_RS03765	COG4591	ABC-type transport system involved in lipoprotein release permease component
ASE18_RS03775	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ASE18_RS03780	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ASE18_RS03790	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ASE18_RS03795	COG1177	transmembrane transport
ASE18_RS03820	COG2850	peptidyl-arginine hydroxylation
ASE18_RS03825	COG2205	protein histidine kinase activity
ASE18_RS03830	COG0745	RESPONSE REGULATOR receiver
ASE18_RS03835	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ASE18_RS03855	COG1187	pseudouridine synthase activity
ASE18_RS03860	COG0538	isocitrate dehydrogenase activity
ASE18_RS03865	COG0582	viral genome integration into host DNA
ASE18_RS03930	COG1401	restriction endodeoxyribonuclease activity
ASE18_RS03950	COG5562	phage envelope protein
ASE18_RS03955	COG0789	Transcriptional regulator
ASE18_RS03960	COG2200	EAL domain
ASE18_RS03985	COG2200	EAL domain
ASE18_RS04035	COG2894	cell division
ASE18_RS04060	COG0179	Fumarylacetoacetate (FAA) hydrolase
ASE18_RS04080	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ASE18_RS04085	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ASE18_RS04105	COG2719	SpoVR family
ASE18_RS04115	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASE18_RS04125	COG1619	proteins homologs of microcin C7 resistance protein MccF
ASE18_RS04135	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ASE18_RS04155	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASE18_RS04155	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ASE18_RS04155	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ASE18_RS04160	COG1461	Dihydroxyacetone kinase
ASE18_RS04165	COG2376	Dihydroxyacetone kinase
ASE18_RS04170	COG3284	Transcriptional regulator
ASE18_RS04185	COG0012	GTP binding
ASE18_RS04200	COG0659	secondary active sulfate transmembrane transporter activity
ASE18_RS04205	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ASE18_RS04235	COG3094	Invasion gene expression up-regulator, SirB
ASE18_RS04240	COG2912	Transglutaminase-like superfamily
ASE18_RS04260	COG0387	Pfam Sodium calcium exchanger
ASE18_RS04265	COG4572	Cation transport regulator
ASE18_RS04270	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
ASE18_RS04275	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ASE18_RS04280	COG4932	domain protein
ASE18_RS04285	COG2197	response regulator
ASE18_RS04290	COG3850	Histidine kinase
ASE18_RS04300	COG2223	nitrite transmembrane transporter activity
ASE18_RS04305	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ASE18_RS04310	COG1140	nitrate reductase beta subunit
ASE18_RS04315	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ASE18_RS04320	COG2181	nitrate reductase activity
ASE18_RS04335	COG0788	formyltetrahydrofolate deformylase activity
ASE18_RS04345	COG1752	Esterase of the alpha-beta hydrolase superfamily
ASE18_RS04350	COG0745	RESPONSE REGULATOR receiver
ASE18_RS04355	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ASE18_RS04370	COG1012	belongs to the aldehyde dehydrogenase family
ASE18_RS04370	COG1454	alcohol dehydrogenase
ASE18_RS04375	COG2095	MarC family integral membrane protein
ASE18_RS04380	COG4166	transmembrane transport
ASE18_RS04385	COG0601	transmembrane transport
ASE18_RS04390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASE18_RS04395	COG0444	Belongs to the ABC transporter superfamily
ASE18_RS04400	COG4608	Belongs to the ABC transporter superfamily
ASE18_RS04420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ASE18_RS04425	COG2350	Protein conserved in bacteria
ASE18_RS04430	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ASE18_RS04435	COG1607	acyl-coa hydrolase
ASE18_RS04450	COG3047	cAMP biosynthetic process
ASE18_RS04455	COG3685	Protein conserved in bacteria
ASE18_RS04460	COG3685	Protein conserved in bacteria
ASE18_RS04465	COG3729	General stress protein
ASE18_RS04480	COG0135	phosphoribosylanthranilate isomerase activity
ASE18_RS04480	COG0134	indole-3-glycerol-phosphate synthase activity
ASE18_RS04485	COG0512	Glutamine amidotransferase of anthranilate synthase
ASE18_RS04485	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASE18_RS04490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASE18_RS04495	COG0613	PHP domain protein
ASE18_RS04500	COG0009	L-threonylcarbamoyladenylate synthase
ASE18_RS04505	COG1187	pseudouridine synthase activity
ASE18_RS04510	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ASE18_RS04515	COG1028	Short-chain dehydrogenase reductase Sdr
ASE18_RS04525	COG0616	signal peptide processing
ASE18_RS04540	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ASE18_RS04545	COG0583	DNA-binding transcription factor activity
ASE18_RS04565	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ASE18_RS04575	COG0671	phosphoesterase, PA-phosphatase related
ASE18_RS04580	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ASE18_RS04585	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ASE18_RS04595	COG0023	Translation Initiation Factor
ASE18_RS04605	COG1349	DNA-binding transcription factor activity
ASE18_RS04615	COG5001	Diguanylate cyclase
ASE18_RS04630	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ASE18_RS04630	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ASE18_RS04635	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ASE18_RS04645	COG2852	Protein conserved in bacteria
ASE18_RS04650	COG4172	Belongs to the ABC transporter superfamily
ASE18_RS04655	COG4172	Belongs to the ABC transporter superfamily
ASE18_RS04660	COG4171	peptide transport system, permease
ASE18_RS04665	COG4168	peptide transport system, permease
ASE18_RS04670	COG4166	transmembrane transport
ASE18_RS04685	COG0531	amino acid
ASE18_RS04690	COG0174	glutamine synthetase
ASE18_RS04695	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ASE18_RS04700	COG1396	sequence-specific DNA binding
ASE18_RS04700	COG1917	Cupin 2, conserved barrel domain protein
ASE18_RS04705	COG1012	belongs to the aldehyde dehydrogenase family
ASE18_RS04710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASE18_RS04715	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ASE18_RS04720	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ASE18_RS04725	COG1842	Phage shock protein A
ASE18_RS04735	COG1983	PspC domain protein
ASE18_RS04745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASE18_RS04750	COG0366	Alpha amylase catalytic
ASE18_RS04755	COG1653	transport
ASE18_RS04760	COG1175	transmembrane transport
ASE18_RS04765	COG0395	ABC-type sugar transport system, permease component
ASE18_RS04770	COG1063	alcohol dehydrogenase
ASE18_RS04775	COG1082	Xylose isomerase domain protein TIM barrel
ASE18_RS04780	COG0673	inositol 2-dehydrogenase activity
ASE18_RS04785	COG1554	hydrolase, family 65, central catalytic
ASE18_RS04790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASE18_RS04795	COG3842	ATPase activity
ASE18_RS04805	COG1609	Transcriptional regulator
ASE18_RS04810	COG3106	COG3106 Predicted ATPase
ASE18_RS04820	COG3283	Transcriptional regulator of aromatic amino acids metabolism
ASE18_RS04825	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ASE18_RS04830	COG4948	Mandelate Racemase Muconate Lactonizing
ASE18_RS04835	COG2866	Carboxypeptidase
ASE18_RS04840	COG0702	epimerase
ASE18_RS04845	COG1073	alpha beta
ASE18_RS04850	COG0583	DNA-binding transcription factor activity
ASE18_RS04855	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ASE18_RS04860	COG4166	transmembrane transport
ASE18_RS04865	COG0668	transmembrane transport
ASE18_RS04870	COG3182	Iron-regulated membrane protein
ASE18_RS04875	COG0589	response to stress
ASE18_RS04880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASE18_RS04885	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ASE18_RS04890	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ASE18_RS04900	COG1473	amidohydrolase
ASE18_RS04905	COG1473	amidohydrolase
ASE18_RS04910	COG0583	DNA-binding transcription factor activity
ASE18_RS04915	COG2840	Smr protein MutS2
ASE18_RS04920	COG3706	GGDEF domain
ASE18_RS04935	COG0513	Belongs to the DEAD box helicase family
ASE18_RS04945	COG0589	response to stress
ASE18_RS04950	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASE18_RS04955	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASE18_RS04955	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ASE18_RS04955	COG1013	pyruvate-flavodoxin oxidoreductase activity
ASE18_RS04955	COG0674	pyruvate-flavodoxin oxidoreductase activity
ASE18_RS04960	COG3042	response to heat
ASE18_RS04965	COG3187	Heat shock protein
ASE18_RS04970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ASE18_RS04975	COG2911	Protein conserved in bacteria
ASE18_RS04985	COG3784	Protein of unknown function (DUF1318)
ASE18_RS04990	COG2207	Transcriptional regulator
ASE18_RS04995	COG1012	belongs to the aldehyde dehydrogenase family
ASE18_RS05000	COG3733	amine oxidase
ASE18_RS05005	COG2030	dehydratase
ASE18_RS05005	COG1012	belongs to the aldehyde dehydrogenase family
ASE18_RS05010	COG3396	Phenylacetate-CoA oxygenase
ASE18_RS05015	COG3460	Phenylacetate-CoA oxygenase
ASE18_RS05020	COG3396	Phenylacetate-CoA oxygenase
ASE18_RS05025	COG2151	metal-sulfur cluster biosynthetic enzyme
ASE18_RS05030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASE18_RS05035	COG1024	Enoyl-CoA hydratase
ASE18_RS05040	COG1024	Enoyl-CoA hydratase
ASE18_RS05045	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASE18_RS05050	COG2050	protein possibly involved in aromatic compounds catabolism
ASE18_RS05055	COG0183	Belongs to the thiolase family
ASE18_RS05060	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ASE18_RS05065	COG3327	negative regulation of DNA-templated transcription, initiation
ASE18_RS05070	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ASE18_RS05075	COG0667	Aldo Keto reductase
ASE18_RS05085	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ASE18_RS05090	COG4589	Belongs to the CDS family
ASE18_RS05095	COG2267	carboxylic ester hydrolase activity
ASE18_RS05100	COG0671	phosphoesterase, PA-phosphatase related
ASE18_RS05100	COG2453	phosphatase
ASE18_RS05110	COG1643	Atp-dependent helicase
ASE18_RS05115	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ASE18_RS05120	COG1012	belongs to the aldehyde dehydrogenase family
ASE18_RS05125	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASE18_RS05130	COG3038	cytochrome b561
ASE18_RS05145	COG0840	transmembrane signaling receptor activity
ASE18_RS05150	COG0583	DNA-binding transcription factor activity
ASE18_RS05155	COG5383	Protein conserved in bacteria
ASE18_RS05170	COG2841	Protein conserved in bacteria
ASE18_RS05175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASE18_RS05180	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ASE18_RS05185	COG1275	C4-dicarboxylate transporter malic acid transport protein
ASE18_RS05190	COG0500	methyltransferase
ASE18_RS05205	COG0675	Transposase, IS605 OrfB family
ASE18_RS05210	COG3135	benzoate transporter
ASE18_RS05215	COG1396	sequence-specific DNA binding
ASE18_RS05220	COG0826	peptidase U32
ASE18_RS05235	COG1598	PFAM Uncharacterised protein family UPF0150
ASE18_RS05240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASE18_RS05245	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ASE18_RS05250	COG3842	ATPase activity
ASE18_RS05255	COG1176	ABC-type spermidine putrescine transport system, permease component I
ASE18_RS05260	COG1177	transmembrane transport
ASE18_RS05285	COG3238	Protein conserved in bacteria
ASE18_RS05290	COG1247	-acetyltransferase
ASE18_RS05295	COG2130	NADP-dependent
ASE18_RS05300	COG1802	Transcriptional regulator
ASE18_RS05305	COG4772	TonB-dependent receptor
ASE18_RS05310	COG3391	amine dehydrogenase activity
ASE18_RS05315	COG1113	amino acid transport
ASE18_RS05320	COG0625	glutathione transferase activity
ASE18_RS05335	COG3209	COG3209 Rhs family protein
ASE18_RS05350	COG5433	transposase activity
ASE18_RS05360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ASE18_RS05365	COG2162	N-hydroxyarylamine O-acetyltransferase activity
ASE18_RS05370	COG0384	phenazine biosynthesis protein PhzF
ASE18_RS05375	COG2181	nitrate reductase activity
ASE18_RS05380	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ASE18_RS05385	COG1140	nitrate reductase beta subunit
ASE18_RS05390	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ASE18_RS05395	COG2223	nitrite transmembrane transporter activity
ASE18_RS05405	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASE18_RS05410	COG0697	spore germination
ASE18_RS05415	COG0243	molybdopterin cofactor binding
ASE18_RS05415	COG3383	formate dehydrogenase (NAD+) activity
ASE18_RS05420	COG0243	molybdopterin cofactor binding
ASE18_RS05420	COG3383	formate dehydrogenase (NAD+) activity
ASE18_RS05425	COG0437	4 iron, 4 sulfur cluster binding
ASE18_RS05430	COG2864	formate dehydrogenase
ASE18_RS05435	COG3093	addiction module antidote protein HigA
ASE18_RS05440	COG1064	alcohol dehydrogenase
ASE18_RS05460	COG1764	response to oxidative stress
ASE18_RS05465	COG4608	Belongs to the ABC transporter superfamily
ASE18_RS05470	COG0444	Belongs to the ABC transporter superfamily
ASE18_RS05475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASE18_RS05480	COG0601	transmembrane transport
ASE18_RS05485	COG0747	negative chemotaxis
ASE18_RS05490	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ASE18_RS05495	COG2202	Pas domain
ASE18_RS05495	COG2200	EAL domain
ASE18_RS05495	COG2199	diguanylate cyclase activity
ASE18_RS05505	COG1649	PFAM Uncharacterised BCR, COG1649
ASE18_RS05510	COG0531	amino acid
ASE18_RS05515	COG0076	glutamate decarboxylase activity
ASE18_RS05525	COG0612	Peptidase, M16
ASE18_RS05530	COG4771	TonB-dependent receptor
ASE18_RS05535	COG4178	(ABC) transporter
ASE18_RS05540	COG0641	radical SAM
ASE18_RS05560	COG3119	arylsulfatase activity
ASE18_RS05575	COG0243	molybdopterin cofactor binding
ASE18_RS05580	COG3539	Fimbrial protein
ASE18_RS05585	COG3539	Fimbrial protein
ASE18_RS05590	COG3539	Fimbrial protein
ASE18_RS05595	COG3188	usher protein
ASE18_RS05605	COG3539	Fimbrial protein
ASE18_RS05610	COG4977	sequence-specific DNA binding
ASE18_RS05615	COG3550	peptidyl-serine autophosphorylation
ASE18_RS05620	COG1396	sequence-specific DNA binding
ASE18_RS05625	COG3210	domain, Protein
ASE18_RS05625	COG2911	Protein conserved in bacteria
ASE18_RS05675	COG3781	membrane
ASE18_RS05685	COG2199	diguanylate cyclase activity
ASE18_RS05700	COG2066	Belongs to the glutaminase family
ASE18_RS05705	COG1012	belongs to the aldehyde dehydrogenase family
ASE18_RS05710	COG0583	DNA-binding transcription factor activity
ASE18_RS05735	COG1846	Transcriptional regulator
ASE18_RS05740	COG4977	sequence-specific DNA binding
ASE18_RS05750	COG2723	6-phospho-beta-galactosidase activity
ASE18_RS05760	COG1447	Phosphotransferase system cellobiose-specific component IIA
ASE18_RS05765	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASE18_RS05775	COG2188	Transcriptional regulator
ASE18_RS05780	COG0697	spore germination
ASE18_RS05785	COG2814	Major facilitator Superfamily
ASE18_RS05795	COG3706	GGDEF domain
ASE18_RS05800	COG3111	PFAM Bacterial OB fold (BOF) protein
ASE18_RS05805	COG1546	Belongs to the CinA family
ASE18_RS05810	COG0339	signal peptide processing
ASE18_RS05815	COG4221	oxidoreductase activity
ASE18_RS05820	COG1802	Transcriptional regulator
ASE18_RS05830	COG0246	Mannitol dehydrogenase
ASE18_RS05835	COG0477	Major facilitator Superfamily
ASE18_RS05875	COG0484	heat shock protein binding
ASE18_RS05880	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ASE18_RS05885	COG1403	HNH endonuclease
ASE18_RS05935	COG1846	Transcriptional regulator
ASE18_RS05955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASE18_RS05965	COG0582	viral genome integration into host DNA
ASE18_RS05970	COG1063	alcohol dehydrogenase
ASE18_RS05975	COG4948	Mandelate Racemase Muconate Lactonizing
ASE18_RS05990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASE18_RS06005	COG0243	molybdopterin cofactor binding
ASE18_RS06010	COG0243	molybdopterin cofactor binding
ASE18_RS06015	COG0437	4 iron, 4 sulfur cluster binding
ASE18_RS06020	COG3302	dmso reductase anchor subunit
ASE18_RS06025	COG3381	protein complex oligomerization
ASE18_RS06035	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ASE18_RS06040	COG1940	carbohydrate kinase activity
ASE18_RS06045	COG0583	DNA-binding transcription factor activity
ASE18_RS06050	COG2814	Major facilitator Superfamily
ASE18_RS06065	COG3591	Belongs to the peptidase S1B family
ASE18_RS06080	COG0628	permease
ASE18_RS06085	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ASE18_RS06090	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ASE18_RS06100	COG0531	amino acid
ASE18_RS06110	COG3136	membrane protein required for alginate biosynthesis
ASE18_RS06115	COG0745	RESPONSE REGULATOR receiver
ASE18_RS06120	COG2205	protein histidine kinase activity
ASE18_RS06130	COG0114	fumarate hydratase activity
ASE18_RS06135	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ASE18_RS06135	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ASE18_RS06140	COG1482	cell wall glycoprotein biosynthetic process
ASE18_RS06145	COG5339	Protein conserved in bacteria
ASE18_RS06160	COG3250	beta-galactosidase activity
ASE18_RS06165	COG1309	transcriptional regulator
ASE18_RS06170	COG1028	Short-chain dehydrogenase reductase Sdr
ASE18_RS06175	COG1609	Transcriptional regulator
ASE18_RS06180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASE18_RS06180	COG1263	PTS System
ASE18_RS06185	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ASE18_RS06195	COG0673	inositol 2-dehydrogenase activity
ASE18_RS06235	COG4659	FMN binding
ASE18_RS06245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ASE18_RS06255	COG3104	oligopeptide transport
ASE18_RS06260	COG0625	glutathione transferase activity
ASE18_RS06265	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ASE18_RS06280	COG3895	Periplasmic Protein
ASE18_RS06290	COG3133	Outer membrane lipoprotein
ASE18_RS06305	COG1566	PFAM secretion protein HlyD family protein
ASE18_RS06310	COG1289	transmembrane transporter activity
ASE18_RS06315	COG2032	superoxide dismutase activity
ASE18_RS06320	COG4989	oxidoreductase activity
ASE18_RS06325	COG3313	Fe-S protein
ASE18_RS06330	COG1309	transcriptional regulator
ASE18_RS06335	COG1902	pentaerythritol trinitrate reductase activity
ASE18_RS06340	COG0346	lactoylglutathione lyase activity
ASE18_RS06350	COG1201	RNA secondary structure unwinding
ASE18_RS06355	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ASE18_RS06360	COG0791	NLP P60 protein
ASE18_RS06365	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ASE18_RS06370	COG2814	Major facilitator Superfamily
ASE18_RS06385	COG0583	DNA-binding transcription factor activity
ASE18_RS06390	COG2814	Major facilitator Superfamily
ASE18_RS06395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASE18_RS06400	COG0307	riboflavin synthase, alpha
ASE18_RS06410	COG3468	outer membrane autotransporter barrel domain protein
ASE18_RS06430	COG4529	Protein conserved in bacteria
ASE18_RS06440	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
ASE18_RS06445	COG0437	4 iron, 4 sulfur cluster binding
ASE18_RS06455	COG2414	aldehyde ferredoxin oxidoreductase
ASE18_RS06460	COG0437	4 iron, 4 sulfur cluster binding
ASE18_RS06470	COG0469	pyruvate kinase activity
ASE18_RS06475	COG4238	major outer membrane lipoprotein
ASE18_RS06480	COG1376	ErfK ybiS ycfS ynhG family protein
ASE18_RS06495	COG0719	Fe-S assembly protein
ASE18_RS06500	COG0396	ATPase activity
ASE18_RS06505	COG0719	Fe-S assembly protein
ASE18_RS06510	COG0316	Belongs to the HesB IscA family
ASE18_RS06520	COG2050	protein possibly involved in aromatic compounds catabolism
ASE18_RS06525	COG0247	lactate metabolic process
ASE18_RS06525	COG0277	FAD linked oxidase domain protein
ASE18_RS06530	COG0628	permease
ASE18_RS06540	COG0738	Major facilitator superfamily
ASE18_RS06545	COG2271	Major facilitator Superfamily
ASE18_RS06560	COG4670	ketone body catabolic process
ASE18_RS06565	COG1960	acyl-CoA dehydrogenase activity
ASE18_RS06570	COG1917	Cupin 2, conserved barrel domain protein
ASE18_RS06570	COG2207	Transcriptional regulator
ASE18_RS06580	COG2086	electron transfer activity
ASE18_RS06585	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ASE18_RS06590	COG0644	oxidoreductase
ASE18_RS06595	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ASE18_RS06600	COG0318	PFAM AMP-dependent synthetase and ligase
ASE18_RS06605	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ASE18_RS06605	COG0574	Belongs to the PEP-utilizing enzyme family
ASE18_RS06620	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASE18_RS06625	COG4256	Hemin uptake protein
ASE18_RS06635	COG2200	EAL domain
ASE18_RS06640	COG0791	NLP P60 protein
ASE18_RS06650	COG0386	Belongs to the glutathione peroxidase family
ASE18_RS06710	COG3137	Salt-induced outer membrane protein
ASE18_RS06715	COG1105	Belongs to the carbohydrate kinase PfkB family
ASE18_RS06725	COG3001	Fructosamine kinase
ASE18_RS06735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASE18_RS06740	COG1988	membrane-bound metal-dependent
ASE18_RS06745	COG1823	symporter activity
ASE18_RS06760	COG0753	catalase activity
ASE18_RS06770	COG1486	melibiose metabolic process
ASE18_RS06775	COG2169	Transcriptional regulator
ASE18_RS06775	COG1917	Cupin 2, conserved barrel domain protein
ASE18_RS06780	COG1447	Phosphotransferase system cellobiose-specific component IIA
ASE18_RS06785	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASE18_RS06790	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ASE18_RS06795	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASE18_RS06810	COG0322	excinuclease ABC activity
ASE18_RS06820	COG3678	ATP-independent chaperone mediated protein folding
ASE18_RS06850	COG0708	Exodeoxyribonuclease III
ASE18_RS06855	COG0398	Pfam SNARE associated Golgi protein
ASE18_RS06865	COG0398	Pfam SNARE associated Golgi protein
ASE18_RS06870	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ASE18_RS06875	COG4134	Bacterial extracellular solute-binding protein
ASE18_RS06880	COG4135	transport system, permease component
ASE18_RS06885	COG4136	ATPase activity
ASE18_RS06890	COG2897	thiosulfate sulfurtransferase activity
ASE18_RS06895	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ASE18_RS06900	COG0494	nUDIX hydrolase
ASE18_RS06910	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ASE18_RS06920	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ASE18_RS06935	COG0778	Nitroreductase
ASE18_RS06945	COG0616	signal peptide processing
ASE18_RS06950	COG0252	asparaginase activity
ASE18_RS06955	COG1335	isochorismatase
ASE18_RS06960	COG3139	Protein of unknown function (DUF1315)
ASE18_RS06970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASE18_RS06975	COG0676	glucose-6-phosphate 1-epimerase activity
ASE18_RS06980	COG0656	L-ascorbic acid biosynthetic process
ASE18_RS06985	COG3713	MltA-interacting MipA family protein
ASE18_RS06990	COG2766	serine protein kinase
ASE18_RS07000	COG2199	diguanylate cyclase activity
ASE18_RS07005	COG2199	diguanylate cyclase activity
ASE18_RS07010	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ASE18_RS07025	COG2207	Transcriptional regulator
ASE18_RS07030	COG2807	transmembrane transport
ASE18_RS07035	COG3189	MarR family transcriptional regulator
ASE18_RS07040	COG3042	response to heat
ASE18_RS07045	COG2203	Gaf domain
ASE18_RS07045	COG2199	diguanylate cyclase activity
ASE18_RS07055	COG2261	transglycosylase associated protein
ASE18_RS07065	COG3615	Tellurite resistance protein tehB
ASE18_RS07075	COG0583	DNA-binding transcription factor activity
ASE18_RS07080	COG0473	3-isopropylmalate dehydrogenase activity
ASE18_RS07085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASE18_RS07090	COG4638	Rieske (2fe-2S)
ASE18_RS07095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASE18_RS07100	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ASE18_RS07105	COG0318	PFAM AMP-dependent synthetase and ligase
ASE18_RS07110	COG3065	identical protein binding
ASE18_RS07115	COG1214	PFAM Peptidase M22, glycoprotease
ASE18_RS07120	COG1199	ATP-dependent helicase activity
ASE18_RS07125	COG0251	oxidation-reduction process
ASE18_RS07140	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASE18_RS07150	COG1760	l-serine dehydratase
ASE18_RS07155	COG2200	EAL domain
ASE18_RS07160	COG1253	flavin adenine dinucleotide binding
ASE18_RS07170	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASE18_RS07170	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASE18_RS07175	COG3715	PTS system
ASE18_RS07180	COG3716	PTS system mannose fructose sorbose family IID component
ASE18_RS07200	COG2226	methyltransferase
ASE18_RS07235	COG1414	Transcriptional regulator
ASE18_RS07240	COG2814	Major facilitator Superfamily
ASE18_RS07250	COG0793	Belongs to the peptidase S41A family
ASE18_RS07260	COG1956	GAF domain-containing protein
ASE18_RS07265	COG2995	paraquat-inducible protein a
ASE18_RS07270	COG3008	intermembrane lipid transfer
ASE18_RS07290	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ASE18_RS07305	COG1276	copper resistance
ASE18_RS07310	COG2372	response to copper ion
ASE18_RS07320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASE18_RS07325	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASE18_RS07330	COG1770	oligopeptidase
ASE18_RS07335	COG2979	Protein of unknown function (DUF533)
ASE18_RS07350	COG3141	response to X-ray
ASE18_RS07360	COG0800	Aldolase
ASE18_RS07365	COG0129	dihydroxy-acid dehydratase activity
ASE18_RS07370	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ASE18_RS07380	COG1737	Transcriptional regulator
ASE18_RS07385	COG0469	pyruvate kinase activity
ASE18_RS07390	COG1560	Kdo2-lipid A biosynthetic process
ASE18_RS07395	COG0739	heme binding
ASE18_RS07400	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ASE18_RS07410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASE18_RS07435	COG0217	transcriptional regulatory protein
ASE18_RS07440	COG0494	nUDIX hydrolase
ASE18_RS07450	COG1335	isochorismatase
ASE18_RS07455	COG1801	Protein of unknown function DUF72
ASE18_RS07460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASE18_RS07510	COG1801	Protein of unknown function DUF72
ASE18_RS07515	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ASE18_RS07530	COG0243	molybdopterin cofactor binding
ASE18_RS07535	COG3005	denitrification pathway
ASE18_RS07545	COG3102	Protein conserved in bacteria
ASE18_RS07555	COG3755	Protein conserved in bacteria
ASE18_RS07565	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ASE18_RS07570	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ASE18_RS07575	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ASE18_RS07580	COG0745	RESPONSE REGULATOR receiver
ASE18_RS07590	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ASE18_RS07595	COG0840	transmembrane signaling receptor activity
ASE18_RS07600	COG0840	transmembrane signaling receptor activity
ASE18_RS07605	COG0835	chemotaxis
ASE18_RS07610	COG2198	Histidine kinase
ASE18_RS07610	COG0643	Histidine kinase
ASE18_RS07615	COG1360	Flagellar Motor Protein
ASE18_RS07620	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ASE18_RS07635	COG0589	response to stress
ASE18_RS07645	COG1877	trehalose-phosphatase activity
ASE18_RS07650	COG1172	Belongs to the binding-protein-dependent transport system permease family
ASE18_RS07655	COG1129	ABC transporter
ASE18_RS07660	COG1879	ABC-type sugar transport system periplasmic component
ASE18_RS07665	COG1528	Iron-storage protein
ASE18_RS07685	COG1528	Iron-storage protein
ASE18_RS07695	COG0814	amino acid
ASE18_RS07700	COG3012	SEC-C Motif Domain Protein
ASE18_RS07700	COG3318	Belongs to the UPF0149 family
ASE18_RS07730	COG2197	response regulator
ASE18_RS07745	COG2197	response regulator
ASE18_RS07750	COG1126	abc transporter atp-binding protein
ASE18_RS07755	COG0765	amino acid transport
ASE18_RS07765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASE18_RS07775	COG1191	sigma factor activity
ASE18_RS07785	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ASE18_RS07790	COG1516	flagellar protein fliS
ASE18_RS07800	COG0366	Alpha amylase catalytic
ASE18_RS07810	COG2391	methyltransferase activity
ASE18_RS07815	COG0425	Belongs to the sulfur carrier protein TusA family
ASE18_RS07820	COG2135	peptidase activity
ASE18_RS07825	COG0675	Transposase, IS605 OrfB family
ASE18_RS07840	COG2207	Transcriptional regulator
ASE18_RS07845	COG1881	PFAM PEBP family protein
ASE18_RS07865	COG1766	The M ring may be actively involved in energy transduction
ASE18_RS07870	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ASE18_RS07875	COG1317	bacterial-type flagellum organization
ASE18_RS07880	COG1157	protein secretion by the type III secretion system
ASE18_RS07885	COG2882	bacterial-type flagellum organization
ASE18_RS07890	COG3144	bacterial-type flagellum assembly
ASE18_RS07895	COG1580	Controls the rotational direction of flagella during chemotaxis
ASE18_RS07900	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ASE18_RS07905	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ASE18_RS07910	COG3190	flagellar
ASE18_RS07915	COG1338	Plays a role in the flagellum-specific transport system
ASE18_RS07920	COG1987	bacterial-type flagellum assembly
ASE18_RS07925	COG1684	flagellar biosynthetic protein fliR
ASE18_RS07930	COG2197	response regulator
ASE18_RS07950	COG3706	GGDEF domain
ASE18_RS07955	COG5475	Uncharacterized small protein (DUF2158)
ASE18_RS07960	COG2354	Protein conserved in bacteria
ASE18_RS07965	COG0697	spore germination
ASE18_RS07970	COG3727	T/G mismatch-specific endonuclease activity
ASE18_RS07975	COG0270	DNA (cytosine-5-)-methyltransferase activity
ASE18_RS07980	COG1418	mRNA catabolic process
ASE18_RS07990	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASE18_RS08005	COG2205	protein histidine kinase activity
ASE18_RS08010	COG0745	RESPONSE REGULATOR receiver
ASE18_RS08015	COG2351	hydroxyisourate hydrolase activity
ASE18_RS08030	COG3443	Belongs to the bacterial solute-binding protein 9 family
ASE18_RS08055	COG0582	viral genome integration into host DNA
ASE18_RS08110	COG2801	Transposase and inactivated derivatives
ASE18_RS08125	COG2801	Transposase and inactivated derivatives
ASE18_RS08215	COG0582	viral genome integration into host DNA
ASE18_RS08220	COG1169	isochorismate synthase
ASE18_RS08225	COG2814	Major facilitator Superfamily
ASE18_RS08230	COG1132	(ABC) transporter
ASE18_RS08245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ASE18_RS08245	COG2226	methyltransferase
ASE18_RS08245	COG3433	isochorismatase activity
ASE18_RS08265	COG1021	2,3-dihydroxybenzoate-AMP ligase
ASE18_RS08270	COG4771	TonB-dependent receptor
ASE18_RS08275	COG1388	LysM domain
ASE18_RS08275	COG2373	Large extracellular alpha-helical protein
ASE18_RS08275	COG4932	domain protein
ASE18_RS08280	COG1470	cell adhesion involved in biofilm formation
ASE18_RS08280	COG1388	LysM domain
ASE18_RS08285	COG1388	LysM domain
ASE18_RS08285	COG1470	cell adhesion involved in biofilm formation
ASE18_RS08290	COG1470	cell adhesion involved in biofilm formation
ASE18_RS08290	COG1388	LysM domain
ASE18_RS08300	COG0477	Major facilitator Superfamily
ASE18_RS08305	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ASE18_RS08310	COG0217	transcriptional regulatory protein
ASE18_RS08320	COG0534	Mate efflux family protein
ASE18_RS08330	COG0583	DNA-binding transcription factor activity
ASE18_RS08335	COG0583	DNA-binding transcription factor activity
ASE18_RS08345	COG1376	ErfK ybiS ycfS ynhG family protein
ASE18_RS08360	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
ASE18_RS08375	COG2801	Transposase and inactivated derivatives
ASE18_RS08385	COG1735	metal-dependent hydrolase with the TIM-barrel fold
ASE18_RS08390	COG0405	Gamma-glutamyltransferase
ASE18_RS08475	COG3468	outer membrane autotransporter barrel domain protein
ASE18_RS08500	COG4917	ethanolamine utilization protein
ASE18_RS08510	COG1289	transmembrane transporter activity
ASE18_RS08520	COG1686	Belongs to the peptidase S11 family
ASE18_RS08525	COG2925	Exonuclease
ASE18_RS08530	COG0425	Belongs to the sulfur carrier protein TusA family
ASE18_RS08535	COG2391	methyltransferase activity
ASE18_RS08540	COG0531	amino acid
ASE18_RS08545	COG0583	DNA-binding transcription factor activity
ASE18_RS08550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASE18_RS08555	COG4115	mRNA cleavage
ASE18_RS08560	COG2161	toxin-antitoxin pair type II binding
ASE18_RS08570	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ASE18_RS08580	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ASE18_RS08580	COG0131	Imidazoleglycerol-phosphate dehydratase
ASE18_RS08585	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ASE18_RS08620	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ASE18_RS08630	COG0662	Cupin 2, conserved barrel domain protein
ASE18_RS08630	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ASE18_RS08645	COG0438	transferase activity, transferring glycosyl groups
ASE18_RS08670	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ASE18_RS08675	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ASE18_RS08685	COG0438	transferase activity, transferring glycosyl groups
ASE18_RS08690	COG2327	Polysaccharide pyruvyl transferase
ASE18_RS08695	COG2244	polysaccharide biosynthetic process
ASE18_RS08700	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASE18_RS08705	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASE18_RS08710	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ASE18_RS08710	COG0662	Cupin 2, conserved barrel domain protein
ASE18_RS08715	COG0297	glycogen (starch) synthase activity
ASE18_RS08720	COG1051	belongs to the nudix hydrolase family
ASE18_RS08725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASE18_RS08730	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ASE18_RS08735	COG0110	maltose O-acetyltransferase activity
ASE18_RS08740	COG1216	Glycosyl transferase, family 2
ASE18_RS08750	COG0438	transferase activity, transferring glycosyl groups
ASE18_RS08755	COG1045	serine acetyltransferase
ASE18_RS08760	COG0463	Glycosyl transferase, family 2
ASE18_RS08765	COG3206	protein involved in exopolysaccharide biosynthesis
ASE18_RS08765	COG0489	protein tyrosine kinase activity
ASE18_RS08770	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASE18_RS08775	COG1596	polysaccharide export
ASE18_RS08780	COG1253	flavin adenine dinucleotide binding
ASE18_RS08785	COG2982	Protein involved in outer membrane biogenesis
ASE18_RS08795	COG0572	uridine kinase
ASE18_RS08800	COG3447	MASE1 domain protein
ASE18_RS08800	COG5001	Diguanylate cyclase
ASE18_RS08800	COG5002	protein histidine kinase activity
ASE18_RS08805	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ASE18_RS08810	COG0443	Heat shock 70 kDa protein
ASE18_RS08815	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
ASE18_RS08820	COG3779	Protein conserved in bacteria
ASE18_RS08825	COG0631	protein serine/threonine phosphatase activity
ASE18_RS08830	COG4245	von Willebrand factor, type A
ASE18_RS08855	COG2205	protein histidine kinase activity
ASE18_RS08860	COG0745	RESPONSE REGULATOR receiver
ASE18_RS08870	COG3609	addiction module antidote protein, CC2985 family
ASE18_RS08880	COG0826	peptidase U32
ASE18_RS08905	COG1063	alcohol dehydrogenase
ASE18_RS08910	COG3775	system Galactitol-specific IIC component
ASE18_RS08915	COG3414	Phosphotransferase system galactitol-specific IIB component
ASE18_RS08920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASE18_RS08935	COG1830	Aldolase
ASE18_RS08940	COG2211	Major facilitator Superfamily
ASE18_RS08945	COG1397	ADP-ribosylglycohydrolase
ASE18_RS08950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASE18_RS08955	COG2188	Transcriptional regulator
ASE18_RS08960	COG3757	hydrolase, family 25
ASE18_RS08965	COG3757	hydrolase, family 25
ASE18_RS08970	COG0351	phosphomethylpyrimidine kinase
ASE18_RS08990	COG5455	response to cobalt ion
ASE18_RS08995	COG3539	Fimbrial protein
ASE18_RS09000	COG3188	usher protein
ASE18_RS09005	COG3121	Chaperone
ASE18_RS09010	COG3539	Fimbrial protein
ASE18_RS09025	COG0489	protein tyrosine kinase activity
ASE18_RS09035	COG3831	ATPase activity
ASE18_RS09050	COG0714	Associated with various cellular activities
ASE18_RS09055	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ASE18_RS09060	COG3552	Protein containing von Willebrand factor type A (VWA) domain
ASE18_RS09065	COG4715	Zinc finger, swim domain protein
ASE18_RS09070	COG4808	Protein conserved in bacteria
ASE18_RS09075	COG4807	Protein conserved in bacteria
ASE18_RS09080	COG3279	Response regulator of the LytR AlgR family
ASE18_RS09085	COG3275	phosphorelay sensor kinase activity
ASE18_RS09090	COG0789	Transcriptional regulator
ASE18_RS09100	COG1174	glycine betaine transport
ASE18_RS09105	COG1125	glycine betaine transport
ASE18_RS09110	COG1174	glycine betaine transport
ASE18_RS09115	COG1732	Glycine betaine
ASE18_RS09120	COG1472	Belongs to the glycosyl hydrolase 3 family
ASE18_RS09125	COG0277	FAD linked oxidase domain protein
ASE18_RS09130	COG1686	Belongs to the peptidase S11 family
ASE18_RS09140	COG0586	Pfam SNARE associated Golgi protein
ASE18_RS09145	COG1028	Short-chain dehydrogenase reductase Sdr
ASE18_RS09160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASE18_RS09170	COG1346	cytolysis
ASE18_RS09180	COG2949	membrane
ASE18_RS09190	COG0493	'glutamate synthase
ASE18_RS09195	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ASE18_RS09195	COG0167	dihydroorotate dehydrogenase activity
ASE18_RS09200	COG4211	Belongs to the binding-protein-dependent transport system permease family
ASE18_RS09205	COG1129	ABC transporter
ASE18_RS09210	COG1879	ABC-type sugar transport system periplasmic component
ASE18_RS09215	COG1609	Transcriptional regulator
ASE18_RS09225	COG2311	Membrane
ASE18_RS09240	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ASE18_RS09245	COG4771	TonB-dependent receptor
ASE18_RS09250	COG0833	amino acid
ASE18_RS09255	COG0583	DNA-binding transcription factor activity
ASE18_RS09260	COG2855	membrane
ASE18_RS09270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASE18_RS09270	COG1522	sequence-specific DNA binding
ASE18_RS09275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ASE18_RS09285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASE18_RS09290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ASE18_RS09295	COG2313	pseudouridylate synthase activity
ASE18_RS09300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASE18_RS09305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASE18_RS09305	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ASE18_RS09305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASE18_RS09310	COG1105	Belongs to the carbohydrate kinase PfkB family
ASE18_RS09315	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASE18_RS09315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASE18_RS09320	COG2814	Major facilitator Superfamily
ASE18_RS09335	COG0246	Mannitol dehydrogenase
ASE18_RS09340	COG0523	cobalamin synthesis protein
ASE18_RS09345	COG0671	phosphoesterase, PA-phosphatase related
ASE18_RS09350	COG0791	NLP P60 protein
ASE18_RS09355	COG2200	EAL domain
ASE18_RS09360	COG4166	transmembrane transport
ASE18_RS09365	COG4174	ABC transporter (Permease)
ASE18_RS09370	COG4239	(ABC) transporter, permease
ASE18_RS09375	COG4172	Belongs to the ABC transporter superfamily
ASE18_RS09385	COG2814	Major facilitator Superfamily
ASE18_RS09390	COG1187	pseudouridine synthase activity
ASE18_RS09395	COG1061	Type III restriction enzyme res subunit
ASE18_RS09415	COG3083	sulfuric ester hydrolase activity
ASE18_RS09425	COG3468	outer membrane autotransporter barrel domain protein
ASE18_RS09435	COG2197	response regulator
ASE18_RS09440	COG4235	cytochrome complex assembly
ASE18_RS09440	COG3088	subunit of a heme lyase
ASE18_RS09445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASE18_RS09450	COG1138	Cytochrome C-type biogenesis protein
ASE18_RS09460	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASE18_RS09465	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASE18_RS09470	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASE18_RS09475	COG4133	protoheme IX ABC transporter activity
ASE18_RS09480	COG3005	denitrification pathway
ASE18_RS09485	COG3043	anaerobic respiration
ASE18_RS09490	COG0348	domain, Protein
ASE18_RS09495	COG0437	4 iron, 4 sulfur cluster binding
ASE18_RS09505	COG3062	negative regulation of establishment of protein localization
ASE18_RS09510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASE18_RS09510	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASE18_RS09530	COG4615	Cyclic peptide transporter
ASE18_RS09535	COG3145	DNA-N1-methyladenine dioxygenase activity
ASE18_RS09540	COG2169	Transcriptional regulator
ASE18_RS09540	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ASE18_RS09545	COG1477	protein flavinylation
ASE18_RS09550	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASE18_RS09565	COG0642	Histidine kinase
ASE18_RS09565	COG2198	Histidine kinase
ASE18_RS09570	COG2197	response regulator
ASE18_RS09575	COG2205	protein histidine kinase activity
ASE18_RS09575	COG0784	Response regulator, receiver
ASE18_RS09580	COG3852	Histidine kinase
ASE18_RS09585	COG2204	response regulator
ASE18_RS09590	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ASE18_RS09595	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ASE18_RS09600	COG2031	fatty acid transporter
ASE18_RS09605	COG0183	Belongs to the thiolase family
ASE18_RS09610	COG4676	Protein conserved in bacteria
ASE18_RS09615	COG5445	Predicted secreted protein (DUF2300)
ASE18_RS09620	COG2373	Large extracellular alpha-helical protein
ASE18_RS09625	COG3234	Protein of unknown function (DUF1175)
ASE18_RS09630	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
ASE18_RS09635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ASE18_RS09645	COG3468	outer membrane autotransporter barrel domain protein
ASE18_RS09655	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASE18_RS09660	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASE18_RS09665	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASE18_RS09670	COG3642	lipopolysaccharide core region biosynthetic process
ASE18_RS09675	COG0583	DNA-binding transcription factor activity
ASE18_RS09695	COG0584	glycerophosphoryl diester phosphodiesterase
ASE18_RS09700	COG2271	Major facilitator Superfamily
ASE18_RS09705	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ASE18_RS09715	COG0247	lactate metabolic process
ASE18_RS09720	COG5464	transposase or invertase
ASE18_RS09735	COG2271	Major facilitator Superfamily
ASE18_RS09745	COG1414	Transcriptional regulator
ASE18_RS09810	COG0318	PFAM AMP-dependent synthetase and ligase
ASE18_RS09820	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ASE18_RS09835	COG1169	isochorismate synthase
ASE18_RS09840	COG4575	ribosome binding
ASE18_RS09845	COG2153	protein acetylation
ASE18_RS09860	COG2304	oxidoreductase activity
ASE18_RS09865	COG2234	aminopeptidase activity
ASE18_RS09880	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASE18_RS09885	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASE18_RS09895	COG0839	Belongs to the complex I subunit 6 family
ASE18_RS09910	COG1034	ATP synthesis coupled electron transport
ASE18_RS09915	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ASE18_RS09920	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ASE18_RS09940	COG0583	DNA-binding transcription factor activity
ASE18_RS09945	COG0436	Aminotransferase
ASE18_RS09955	COG0471	metal ion transport
ASE18_RS09955	COG0490	domain, Protein
ASE18_RS09960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASE18_RS09980	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ASE18_RS09985	COG0280	phosphate acetyltransferase
ASE18_RS09985	COG0857	belongs to the CobB CobQ family
ASE18_RS09990	COG1288	antiporter activity
ASE18_RS09995	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ASE18_RS10000	COG0622	Phosphoesterase
ASE18_RS10005	COG0625	glutathione transferase activity
ASE18_RS10010	COG0625	glutathione transferase activity
ASE18_RS10015	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ASE18_RS10020	COG1090	epimerase
ASE18_RS10025	COG5464	transposase or invertase
ASE18_RS10030	COG4598	ABC transporter
ASE18_RS10035	COG4160	amino acid transport
ASE18_RS10040	COG4215	(ABC) transporter
ASE18_RS10045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASE18_RS10050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASE18_RS10055	COG0163	prenyltransferase activity
ASE18_RS10060	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ASE18_RS10065	COG1286	toxin biosynthetic process
ASE18_RS10070	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ASE18_RS10075	COG0285	dihydrofolate synthase activity
ASE18_RS10085	COG0586	Pfam SNARE associated Golgi protein
ASE18_RS10095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASE18_RS10110	COG2814	Major facilitator Superfamily
ASE18_RS10115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASE18_RS10130	COG3101	peptidyl-lysine hydroxylation
ASE18_RS10135	COG0730	response to heat
ASE18_RS10165	COG3539	Fimbrial protein
ASE18_RS10170	COG3539	Fimbrial protein
ASE18_RS10175	COG3539	Fimbrial protein
ASE18_RS10180	COG3121	Chaperone
ASE18_RS10185	COG3188	usher protein
ASE18_RS10190	COG3539	Fimbrial protein
ASE18_RS10195	COG2062	phosphohistidine phosphatase, SixA
ASE18_RS10210	COG3691	Protein conserved in bacteria
ASE18_RS10215	COG2067	long-chain fatty acid transport protein
ASE18_RS10230	COG2853	Lipoprotein
ASE18_RS10235	COG2116	formate transmembrane transporter activity
ASE18_RS10270	COG2610	gluconate transmembrane transporter activity
ASE18_RS10280	COG0477	Major facilitator Superfamily
ASE18_RS10285	COG1566	PFAM secretion protein HlyD family protein
ASE18_RS10290	COG2197	response regulator
ASE18_RS10295	COG2198	Histidine kinase
ASE18_RS10295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASE18_RS10295	COG2205	protein histidine kinase activity
ASE18_RS10295	COG0784	Response regulator, receiver
ASE18_RS10300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASE18_RS10305	COG0679	Auxin Efflux Carrier
ASE18_RS10310	COG0028	Belongs to the TPP enzyme family
ASE18_RS10340	COG1560	Kdo2-lipid A biosynthetic process
ASE18_RS10345	COG0436	Aminotransferase
ASE18_RS10350	COG3275	phosphorelay sensor kinase activity
ASE18_RS10355	COG3279	Response regulator of the LytR AlgR family
ASE18_RS10360	COG2207	Transcriptional regulator
ASE18_RS10370	COG1363	Peptidase, m42
ASE18_RS10375	COG0006	proline dipeptidase activity
ASE18_RS10380	COG0006	proline dipeptidase activity
ASE18_RS10385	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASE18_RS10390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASE18_RS10420	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ASE18_RS10425	COG2200	EAL domain
ASE18_RS10425	COG2199	diguanylate cyclase activity
ASE18_RS10440	COG3415	Transposase
ASE18_RS10445	COG3415	Transposase
ASE18_RS10475	COG0583	DNA-binding transcription factor activity
ASE18_RS10485	COG2211	Major facilitator Superfamily
ASE18_RS10490	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ASE18_RS10500	COG0583	DNA-binding transcription factor activity
ASE18_RS10505	COG0385	Bile acid
ASE18_RS10510	COG3530	Putative quorum-sensing-regulated virulence factor
ASE18_RS10530	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ASE18_RS10535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASE18_RS10540	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ASE18_RS10545	COG2190	(PTS) system
ASE18_RS10560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ASE18_RS10565	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ASE18_RS10570	COG4208	sulfate ABC transporter
ASE18_RS10575	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ASE18_RS10580	COG4150	thiosulfate binding
ASE18_RS10585	COG1028	Short-chain dehydrogenase reductase Sdr
ASE18_RS10605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ASE18_RS10610	COG2837	iron assimilation
ASE18_RS10630	COG0860	N-Acetylmuramoyl-L-alanine amidase
ASE18_RS10640	COG2207	Transcriptional regulator
ASE18_RS10645	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ASE18_RS10650	COG4816	utilization protein
ASE18_RS10660	COG4303	Ethanolamine ammonia lyase large subunit
ASE18_RS10665	COG4819	ethanolamine utilization protein
ASE18_RS10670	COG3192	ethanolamine utilization protein
ASE18_RS10675	COG1454	alcohol dehydrogenase
ASE18_RS10680	COG4820	ethanolamine utilization protein (EutJ)
ASE18_RS10685	COG1012	belongs to the aldehyde dehydrogenase family
ASE18_RS10690	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
ASE18_RS10695	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ASE18_RS10700	COG0280	phosphate acetyltransferase
ASE18_RS10705	COG0280	phosphate acetyltransferase
ASE18_RS10710	COG4812	Cobalamin adenosyltransferase
ASE18_RS10715	COG4766	ethanolamine catabolic process
ASE18_RS10720	COG4917	ethanolamine utilization protein
ASE18_RS10725	COG4810	utilization protein
ASE18_RS10730	COG0281	malic enzyme
ASE18_RS10730	COG0280	phosphate acetyltransferase
ASE18_RS10735	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ASE18_RS10740	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ASE18_RS10745	COG5342	invasion associated locus B
ASE18_RS10755	COG0493	'glutamate synthase
ASE18_RS10755	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASE18_RS10760	COG3850	Histidine kinase
ASE18_RS10765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASE18_RS10775	COG1393	Belongs to the ArsC family
ASE18_RS10790	COG0400	carboxylic ester hydrolase activity
ASE18_RS10800	COG2321	neutral zinc metallopeptidase
ASE18_RS10825	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ASE18_RS10835	COG2716	regulation of RNA biosynthetic process
ASE18_RS10840	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ASE18_RS10845	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASE18_RS10850	COG0651	ATP synthesis coupled electron transport
ASE18_RS10855	COG0651	ATP synthesis coupled electron transport
ASE18_RS10860	COG0650	Formate hydrogenlyase subunit 4
ASE18_RS10865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASE18_RS10870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASE18_RS10875	COG4237	Hydrogenase 4 membrane
ASE18_RS10880	COG0651	ATP synthesis coupled electron transport
ASE18_RS10885	COG3261	NADH dehydrogenase
ASE18_RS10885	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ASE18_RS10890	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASE18_RS10895	COG3260	NADH ubiquinone oxidoreductase 20
ASE18_RS10905	COG3604	Transcriptional regulator
ASE18_RS10910	COG2116	formate transmembrane transporter activity
ASE18_RS10915	COG0628	permease
ASE18_RS10920	COG4783	chaperone-mediated protein folding
ASE18_RS10925	COG1393	Belongs to the ArsC family
ASE18_RS10935	COG2233	PERMEase
ASE18_RS10950	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ASE18_RS10955	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ASE18_RS10960	COG0248	Ppx GppA phosphatase
ASE18_RS10965	COG2200	EAL domain
ASE18_RS10980	COG3133	Outer membrane lipoprotein
ASE18_RS10995	COG0517	IMP dehydrogenase activity
ASE18_RS10995	COG0516	GMP reductase activity
ASE18_RS11005	COG1645	bacterial-type flagellum-dependent swarming motility
ASE18_RS11020	COG2976	Protein conserved in bacteria
ASE18_RS11050	COG4953	penicillin-binding protein 1C
ASE18_RS11055	COG2373	Large extracellular alpha-helical protein
ASE18_RS11060	COG2897	thiosulfate sulfurtransferase activity
ASE18_RS11075	COG2975	iron-sulfur cluster assembly
ASE18_RS11080	COG0633	Ferredoxin
ASE18_RS11100	COG0822	iron-sulfur transferase activity
ASE18_RS11120	COG0483	inositol monophosphate 1-phosphatase activity
ASE18_RS11125	COG1073	alpha beta
ASE18_RS11130	COG3711	transcriptional antiterminator
ASE18_RS11135	COG2814	Major facilitator Superfamily
ASE18_RS11140	COG0583	DNA-binding transcription factor activity
ASE18_RS11145	COG4638	Rieske (2fe-2S)
ASE18_RS11170	COG2259	Doxx family
ASE18_RS11175	COG2017	converts alpha-aldose to the beta-anomer
ASE18_RS11180	COG1063	alcohol dehydrogenase
ASE18_RS11185	COG1172	Belongs to the binding-protein-dependent transport system permease family
ASE18_RS11190	COG1129	ABC transporter
ASE18_RS11195	COG1879	ABC-type sugar transport system periplasmic component
ASE18_RS11200	COG0457	Tetratricopeptide repeat
ASE18_RS11205	COG1940	carbohydrate kinase activity
ASE18_RS11215	COG1017	nitric oxide dioxygenase activity
ASE18_RS11215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASE18_RS11220	COG0347	Belongs to the P(II) protein family
ASE18_RS11225	COG2204	response regulator
ASE18_RS11230	COG3170	Tfp pilus assembly protein FimV
ASE18_RS11235	COG2205	protein histidine kinase activity
ASE18_RS11255	COG0560	Phosphoserine phosphatase
ASE18_RS11260	COG1737	Transcriptional regulator
ASE18_RS11265	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASE18_RS11290	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ASE18_RS11310	COG0681	Belongs to the peptidase S26 family
ASE18_RS11320	COG3086	response to oxidative stress
ASE18_RS11325	COG3026	antisigma factor binding
ASE18_RS11330	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
ASE18_RS11335	COG1595	DNA-templated transcription, initiation
ASE18_RS11345	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ASE18_RS11355	COG0513	Belongs to the DEAD box helicase family
ASE18_RS11365	COG0583	DNA-binding transcription factor activity
ASE18_RS11385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASE18_RS11395	COG3118	belongs to the thioredoxin family
ASE18_RS11400	COG3148	PFAM DTW domain containing protein
ASE18_RS11405	COG0045	succinate-CoA ligase (ADP-forming) activity
ASE18_RS11405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASE18_RS11405	COG1042	CoA-binding domain protein
ASE18_RS11410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASE18_RS11415	COG5544	Lipoprotein
ASE18_RS11420	COG0477	Major facilitator Superfamily
ASE18_RS11450	COG0542	response to heat
ASE18_RS11460	COG0564	pseudouridine synthase activity
ASE18_RS11465	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASE18_RS11475	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ASE18_RS11480	COG1605	Chorismate mutase
ASE18_RS11480	COG0077	Prephenate dehydratase
ASE18_RS11485	COG1605	Chorismate mutase
ASE18_RS11485	COG0287	Prephenate dehydrogenase
ASE18_RS11490	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASE18_RS11505	COG2199	diguanylate cyclase activity
ASE18_RS11510	COG2885	chlorophyll binding
ASE18_RS11535	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ASE18_RS11540	COG4137	Cytochrome C assembly protein
ASE18_RS11545	COG4536	flavin adenine dinucleotide binding
ASE18_RS11565	COG0497	DNA recombination
ASE18_RS11570	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASE18_RS11580	COG2867	negative regulation of translational initiation
ASE18_RS11590	COG0582	viral genome integration into host DNA
ASE18_RS11600	COG1475	DNA binding
ASE18_RS11610	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ASE18_RS11615	COG0732	type I restriction modification DNA specificity domain
ASE18_RS11620	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ASE18_RS11645	COG0366	Alpha amylase catalytic
ASE18_RS11650	COG0366	Alpha amylase catalytic
ASE18_RS11660	COG0579	oxidoreductase
ASE18_RS11665	COG1012	belongs to the aldehyde dehydrogenase family
ASE18_RS11670	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ASE18_RS11675	COG1113	amino acid transport
ASE18_RS11680	COG1802	Transcriptional regulator
ASE18_RS11685	COG1652	LysM domain
ASE18_RS11690	COG0401	homolog of Blt101
ASE18_RS11695	COG0640	Transcriptional regulator
ASE18_RS11700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASE18_RS11705	COG2916	Histone family protein nucleoid-structuring protein H-NS
ASE18_RS11720	COG4575	ribosome binding
ASE18_RS11725	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ASE18_RS11735	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASE18_RS11740	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASE18_RS11745	COG4175	Glycine betaine
ASE18_RS11750	COG4176	ABC-type proline glycine betaine transport system permease component
ASE18_RS11755	COG2113	Glycine betaine
ASE18_RS11760	COG2814	Major facilitator Superfamily
ASE18_RS11765	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ASE18_RS11775	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ASE18_RS11785	COG1846	Transcriptional regulator
ASE18_RS11790	COG1566	PFAM secretion protein HlyD family protein
ASE18_RS11795	COG2814	Major facilitator Superfamily
ASE18_RS11810	COG1238	metal cluster binding
ASE18_RS11815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASE18_RS11845	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ASE18_RS11870	COG1546	Belongs to the CinA family
ASE18_RS11875	COG2951	lytic endotransglycosylase activity
ASE18_RS11880	COG3730	PTS system glucitol sorbitol-specific
ASE18_RS11885	COG3732	PTS system glucitol sorbitol-specific
ASE18_RS11895	COG1028	Short-chain dehydrogenase reductase Sdr
ASE18_RS11900	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASE18_RS11905	COG1349	DNA-binding transcription factor activity
ASE18_RS11930	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ASE18_RS11935	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASE18_RS11940	COG1609	Transcriptional regulator
ASE18_RS11945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASE18_RS11945	COG1263	PTS System
ASE18_RS11950	COG2723	6-phospho-beta-galactosidase activity
ASE18_RS11955	COG5499	transcription regulator containing HTH domain
ASE18_RS11960	COG4680	protein conserved in bacteria
ASE18_RS11970	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ASE18_RS11980	COG3260	NADH ubiquinone oxidoreductase 20
ASE18_RS11985	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASE18_RS11990	COG3261	NADH dehydrogenase
ASE18_RS11990	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ASE18_RS11995	COG0650	Formate hydrogenlyase subunit 4
ASE18_RS12000	COG0651	ATP synthesis coupled electron transport
ASE18_RS12005	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASE18_RS12020	COG0375	protein maturation
ASE18_RS12025	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ASE18_RS12030	COG0298	carbon dioxide binding
ASE18_RS12035	COG0409	Hydrogenase expression formation protein
ASE18_RS12040	COG0309	Hydrogenase expression formation protein (HypE)
ASE18_RS12045	COG3604	Transcriptional regulator
ASE18_RS12060	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ASE18_RS12065	COG1349	DNA-binding transcription factor activity
ASE18_RS12070	COG2084	Dehydrogenase
ASE18_RS12075	COG3395	kinase activity
ASE18_RS12080	COG0235	Class ii aldolase
ASE18_RS12085	COG3622	Belongs to the hyi family
ASE18_RS12090	COG2610	gluconate transmembrane transporter activity
ASE18_RS12095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASE18_RS12100	COG4942	peptidase
ASE18_RS12100	COG1388	LysM domain
ASE18_RS12155	COG2234	aminopeptidase activity
ASE18_RS12160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASE18_RS12165	COG1518	maintenance of DNA repeat elements
ASE18_RS12185	COG1203	CRISPR-associated helicase, Cas3
ASE18_RS12210	COG0720	synthase
ASE18_RS12215	COG0644	oxidoreductase
ASE18_RS12220	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ASE18_RS12225	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ASE18_RS12230	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ASE18_RS12235	COG2086	electron transfer activity
ASE18_RS12240	COG0477	Major facilitator Superfamily
ASE18_RS12245	COG0277	FAD linked oxidase domain protein
ASE18_RS12250	COG1028	Short-chain dehydrogenase reductase Sdr
ASE18_RS12255	COG2223	nitrite transmembrane transporter activity
ASE18_RS12265	COG0602	queuosine metabolic process
ASE18_RS12275	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ASE18_RS12290	COG3956	TIGRFAM MazG family protein
ASE18_RS12295	COG2337	Toxic component of a toxin-antitoxin (TA) module
ASE18_RS12300	COG2336	PFAM SpoVT AbrB
ASE18_RS12305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASE18_RS12310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASE18_RS12315	COG4999	Histidine kinase
ASE18_RS12315	COG3850	Histidine kinase
ASE18_RS12315	COG3437	response regulator, receiver
ASE18_RS12315	COG2205	protein histidine kinase activity
ASE18_RS12320	COG4948	Mandelate Racemase Muconate Lactonizing
ASE18_RS12325	COG4948	Mandelate Racemase Muconate Lactonizing
ASE18_RS12330	COG2271	Major facilitator Superfamily
ASE18_RS12335	COG0716	FMN binding
ASE18_RS12340	COG0564	pseudouridine synthase activity
ASE18_RS12345	COG3098	single-species biofilm formation
ASE18_RS12365	COG1611	Belongs to the LOG family
ASE18_RS12370	COG0814	amino acid
ASE18_RS12375	COG1760	l-serine dehydratase
ASE18_RS12385	COG1454	alcohol dehydrogenase
ASE18_RS12390	COG0235	Class ii aldolase
ASE18_RS12395	COG0738	Major facilitator superfamily
ASE18_RS12405	COG1070	Carbohydrate kinase
ASE18_RS12415	COG1349	DNA-binding transcription factor activity
ASE18_RS12425	COG2363	Small membrane protein
ASE18_RS12430	COG0583	DNA-binding transcription factor activity
ASE18_RS12440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ASE18_RS12445	COG2166	iron-sulfur cluster assembly
ASE18_RS12450	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ASE18_RS12455	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ASE18_RS12475	COG0860	N-Acetylmuramoyl-L-alanine amidase
ASE18_RS12480	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ASE18_RS12480	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASE18_RS12485	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ASE18_RS12490	COG1074	ATP-dependent DNA helicase activity
ASE18_RS12495	COG1025	Belongs to the peptidase M16 family
ASE18_RS12500	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ASE18_RS12505	COG4967	type IV pilus modification protein PilV
ASE18_RS12515	COG4795	General secretion pathway protein
ASE18_RS12520	COG2165	general secretion pathway protein
ASE18_RS12535	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
ASE18_RS12560	COG0861	Integral membrane protein TerC family
ASE18_RS12570	COG0667	Aldo Keto reductase
ASE18_RS12585	COG1609	Transcriptional regulator
ASE18_RS12595	COG0583	DNA-binding transcription factor activity
ASE18_RS12600	COG1794	racemase activity, acting on amino acids and derivatives
ASE18_RS12605	COG2814	Major facilitator Superfamily
ASE18_RS12610	COG1028	Short-chain dehydrogenase reductase Sdr
ASE18_RS12620	COG0183	Belongs to the thiolase family
ASE18_RS12625	COG0814	amino acid
ASE18_RS12630	COG2771	luxR family
ASE18_RS12635	COG3710	Transcriptional regulator
ASE18_RS12655	COG0457	Tetratricopeptide repeat
ASE18_RS12660	COG3710	Transcriptional regulator
ASE18_RS12660	COG0457	Tetratricopeptide repeat
ASE18_RS12685	COG2197	response regulator
ASE18_RS12690	COG2197	response regulator
ASE18_RS12810	COG3387	PFAM Glycoside hydrolase 15-related
ASE18_RS12820	COG4942	peptidase
ASE18_RS12830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ASE18_RS12835	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ASE18_RS12840	COG2080	2 iron, 2 sulfur cluster binding
ASE18_RS12845	COG3829	transcription factor binding
ASE18_RS12850	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ASE18_RS12855	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ASE18_RS12860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASE18_RS12870	COG0549	Belongs to the carbamate kinase family
ASE18_RS12875	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ASE18_RS12875	COG3608	succinylglutamate desuccinylase aspartoacylase
ASE18_RS12880	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ASE18_RS12885	COG2068	MobA-Related Protein
ASE18_RS12890	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASE18_RS12890	COG0493	'glutamate synthase
ASE18_RS12895	COG0402	S-adenosylhomocysteine deaminase activity
ASE18_RS12900	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ASE18_RS12905	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ASE18_RS12905	COG2080	2 iron, 2 sulfur cluster binding
ASE18_RS12910	COG2233	PERMEase
ASE18_RS12915	COG0402	S-adenosylhomocysteine deaminase activity
ASE18_RS12920	COG2252	PERMEase
ASE18_RS12925	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASE18_RS12930	COG0493	'glutamate synthase
ASE18_RS12930	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASE18_RS12940	COG2233	PERMEase
ASE18_RS12965	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ASE18_RS12970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASE18_RS12975	COG4974	Belongs to the 'phage' integrase family
ASE18_RS12980	COG0716	FMN binding
ASE18_RS12990	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ASE18_RS13000	COG1272	protein, Hemolysin III
ASE18_RS13010	COG2723	6-phospho-beta-galactosidase activity
ASE18_RS13015	COG1028	Short-chain dehydrogenase reductase Sdr
ASE18_RS13035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASE18_RS13040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASE18_RS13045	COG0006	proline dipeptidase activity
ASE18_RS13060	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ASE18_RS13070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASE18_RS13090	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ASE18_RS13090	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ASE18_RS13095	COG1703	isobutyryl-CoA mutase activity
ASE18_RS13100	COG1024	Enoyl-CoA hydratase
ASE18_RS13105	COG0427	acetyl-CoA hydrolase
ASE18_RS13110	COG0583	DNA-binding transcription factor activity
ASE18_RS13115	COG2968	Membrane
ASE18_RS13125	COG0668	transmembrane transport
ASE18_RS13130	COG0191	fructose-bisphosphate aldolase activity
ASE18_RS13160	COG1122	ATPase activity
ASE18_RS13165	COG1122	ATPase activity
ASE18_RS13170	COG1072	(Pantothenic acid kinase))
ASE18_RS13180	COG1494	fructose-1,6-bisphosphatase
ASE18_RS13185	COG1063	alcohol dehydrogenase
ASE18_RS13190	COG1662	PFAM IS1 transposase
ASE18_RS13195	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ASE18_RS13200	COG0501	Belongs to the peptidase M48B family
ASE18_RS13215	COG1166	arginine decarboxylase activity
ASE18_RS13240	COG2814	Major facilitator Superfamily
ASE18_RS13250	COG2356	endonuclease I
ASE18_RS13255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ASE18_RS13260	COG0189	ligase activity
ASE18_RS13275	COG2805	Type II/IV secretion system protein
ASE18_RS13280	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ASE18_RS13285	COG0762	integral membrane protein
ASE18_RS13300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASE18_RS13310	COG0252	asparaginase activity
ASE18_RS13325	COG3171	Protein conserved in bacteria
ASE18_RS13335	COG1194	a g-specific adenine glycosylase
ASE18_RS13350	COG2211	Major facilitator Superfamily
ASE18_RS13355	COG1982	Orn Lys Arg decarboxylase major
ASE18_RS13360	COG1811	Na channel or pump
ASE18_RS13370	COG0582	viral genome integration into host DNA
ASE18_RS13410	COG2963	transposase activity
ASE18_RS13420	COG2801	Transposase and inactivated derivatives
ASE18_RS13425	COG1716	ATPase activity
ASE18_RS13425	COG5001	Diguanylate cyclase
ASE18_RS13470	COG1662	PFAM IS1 transposase
ASE18_RS13475	COG4584	PFAM Integrase catalytic
ASE18_RS13480	COG4584	PFAM Integrase catalytic
ASE18_RS13510	COG2433	Pfam Transposase IS66
ASE18_RS13545	COG2003	Belongs to the UPF0758 family
ASE18_RS13580	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ASE18_RS13610	COG1620	l-lactate permease
ASE18_RS13615	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ASE18_RS13620	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ASE18_RS13625	COG0247	lactate metabolic process
ASE18_RS13630	COG0277	FAD linked oxidase domain protein
ASE18_RS13635	COG0277	FAD linked oxidase domain protein
ASE18_RS13640	COG2186	Transcriptional regulator
ASE18_RS13645	COG0456	acetyltransferase
ASE18_RS13650	COG0318	PFAM AMP-dependent synthetase and ligase
ASE18_RS13660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASE18_RS13665	COG0156	8-amino-7-oxononanoate synthase activity
ASE18_RS13675	COG0795	lipopolysaccharide-transporting ATPase activity
ASE18_RS13680	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ASE18_RS13690	COG2244	polysaccharide biosynthetic process
ASE18_RS13695	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ASE18_RS13700	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ASE18_RS13705	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ASE18_RS13710	COG0306	phosphate transporter
ASE18_RS13715	COG0754	glutathionylspermidine amidase activity
ASE18_RS13720	COG0625	glutathione transferase activity
ASE18_RS13725	COG0298	carbon dioxide binding
ASE18_RS13735	COG1773	rubredoxin
ASE18_RS13740	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ASE18_RS13745	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ASE18_RS13750	COG5557	Pfam Polysulphide reductase, NrfD
ASE18_RS13755	COG0437	4 iron, 4 sulfur cluster binding
ASE18_RS13760	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ASE18_RS13780	COG0667	Aldo Keto reductase
ASE18_RS13790	COG1028	Short-chain dehydrogenase reductase Sdr
ASE18_RS13795	COG0848	biopolymer transport protein
ASE18_RS13800	COG0811	peptide transport
ASE18_RS13810	COG0626	cystathionine gamma-synthase activity
ASE18_RS13815	COG0586	Pfam SNARE associated Golgi protein
ASE18_RS13820	COG2207	Transcriptional regulator
ASE18_RS13830	COG1979	alcohol dehydrogenase
ASE18_RS13835	COG0656	L-ascorbic acid biosynthetic process
ASE18_RS13845	COG4238	major outer membrane lipoprotein
ASE18_RS13850	COG1032	radical SAM domain protein
ASE18_RS13855	COG2132	Multicopper oxidase
ASE18_RS13860	COG0204	Acyl-transferase
ASE18_RS13865	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ASE18_RS13870	COG4166	transmembrane transport
ASE18_RS13875	COG2944	sequence-specific DNA binding
ASE18_RS13885	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ASE18_RS13890	COG3111	PFAM Bacterial OB fold (BOF) protein
ASE18_RS13895	COG0745	RESPONSE REGULATOR receiver
ASE18_RS13900	COG0642	Histidine kinase
ASE18_RS13920	COG2249	NAD(P)H dehydrogenase (quinone) activity
ASE18_RS13925	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ASE18_RS13930	COG0187	DNA topoisomerase II activity
ASE18_RS13935	COG3150	esterase
ASE18_RS13940	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ASE18_RS13945	COG3151	Protein conserved in bacteria
ASE18_RS13950	COG0494	nUDIX hydrolase
ASE18_RS13955	COG1538	Outer membrane efflux protein
ASE18_RS13970	COG0754	glutathionylspermidine amidase activity
ASE18_RS13975	COG3384	dioxygenase
ASE18_RS13995	COG2960	long-chain fatty acid transporting porin activity
ASE18_RS14000	COG3539	Fimbrial protein
ASE18_RS14010	COG3121	Chaperone
ASE18_RS14015	COG3539	Fimbrial protein
ASE18_RS14025	COG1585	Membrane protein implicated in regulation of membrane protease activity
ASE18_RS14055	COG3025	triphosphatase activity
ASE18_RS14065	COG4991	sh3 domain protein
ASE18_RS14080	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ASE18_RS14090	COG0583	DNA-binding transcription factor activity
ASE18_RS14095	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ASE18_RS14100	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ASE18_RS14105	COG0471	metal ion transport
ASE18_RS14115	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ASE18_RS14120	COG0358	DNA primase activity
ASE18_RS14125	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASE18_RS14140	COG2375	cellular response to nickel ion
ASE18_RS14145	COG1695	Transcriptional regulator
ASE18_RS14150	COG0840	transmembrane signaling receptor activity
ASE18_RS14160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASE18_RS14165	COG1609	Transcriptional regulator
ASE18_RS14170	COG3250	beta-galactosidase activity
ASE18_RS14175	COG2731	YhcH YjgK YiaL family protein
ASE18_RS14180	COG0531	amino acid
ASE18_RS14190	COG3408	Glycogen debranching enzyme
ASE18_RS14190	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
ASE18_RS14195	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASE18_RS14195	COG1902	pentaerythritol trinitrate reductase activity
ASE18_RS14205	COG1451	nucleotide metabolic process
ASE18_RS14210	COG2949	membrane
ASE18_RS14215	COG0673	inositol 2-dehydrogenase activity
ASE18_RS14220	COG0861	Integral membrane protein TerC family
ASE18_RS14225	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ASE18_RS14235	COG2721	sulfolactate sulfo-lyase activity
ASE18_RS14245	COG2271	Major facilitator Superfamily
ASE18_RS14270	COG2186	Transcriptional regulator
ASE18_RS14275	COG0586	Pfam SNARE associated Golgi protein
ASE18_RS14285	COG1422	Protein of unknown function (DUF1090)
ASE18_RS14290	COG4575	ribosome binding
ASE18_RS14295	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
ASE18_RS14305	COG2259	Doxx family
ASE18_RS14310	COG0435	Glutathione S-transferase
ASE18_RS14315	COG3152	Membrane
ASE18_RS14320	COG3152	Membrane
ASE18_RS14325	COG0583	DNA-binding transcription factor activity
ASE18_RS14330	COG1741	Belongs to the pirin family
ASE18_RS14345	COG0814	amino acid
ASE18_RS14350	COG1760	l-serine dehydratase
ASE18_RS14355	COG0251	oxidation-reduction process
ASE18_RS14360	COG1882	Formate acetyltransferase
ASE18_RS14365	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ASE18_RS14375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ASE18_RS14380	COG0583	DNA-binding transcription factor activity
ASE18_RS14400	COG1929	Belongs to the glycerate kinase type-1 family
ASE18_RS14405	COG2084	Dehydrogenase
ASE18_RS14415	COG2271	Major facilitator Superfamily
ASE18_RS14420	COG2721	sulfolactate sulfo-lyase activity
ASE18_RS14425	COG2002	toxin-antitoxin pair type II binding
ASE18_RS14435	COG1349	DNA-binding transcription factor activity
ASE18_RS14445	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASE18_RS14455	COG3716	PTS system mannose fructose sorbose family IID component
ASE18_RS14460	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASE18_RS14465	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ASE18_RS14470	COG2222	sugar isomerase
ASE18_RS14480	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASE18_RS14485	COG3715	PTS system
ASE18_RS14490	COG3716	PTS system mannose fructose sorbose family IID component
ASE18_RS14495	COG0363	glucosamine-6-phosphate deaminase activity
ASE18_RS14500	COG1662	PFAM IS1 transposase
ASE18_RS14505	COG3188	usher protein
ASE18_RS14510	COG3539	Fimbrial protein
ASE18_RS14515	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ASE18_RS14535	COG2823	Periplasmic or secreted lipoprotein
ASE18_RS14540	COG0701	Predicted permease
ASE18_RS14545	COG0702	epimerase
ASE18_RS14550	COG0693	protein deglycase activity
ASE18_RS14565	COG3153	acetyltransferase
ASE18_RS14570	COG3154	lipid carrier protein
ASE18_RS14575	COG0826	peptidase U32
ASE18_RS14580	COG0826	peptidase U32
ASE18_RS14585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASE18_RS14590	COG0814	amino acid
ASE18_RS14600	COG0513	Belongs to the DEAD box helicase family
ASE18_RS14635	COG0195	Participates in both transcription termination and antitermination
ASE18_RS14665	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASE18_RS14675	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ASE18_RS14680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASE18_RS14690	COG1534	Rna-binding protein
ASE18_RS14695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASE18_RS14700	COG2027	D-alanyl-D-alanine carboxypeptidase
ASE18_RS14710	COG0697	spore germination
ASE18_RS14725	COG0142	geranyltranstransferase activity
ASE18_RS14730	COG3423	Transcriptional regulator
ASE18_RS14740	COG5007	Belongs to the BolA IbaG family
ASE18_RS14745	COG3113	response to antibiotic
ASE18_RS14750	COG2854	intermembrane phospholipid transfer
ASE18_RS14755	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ASE18_RS14760	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ASE18_RS14765	COG1127	ABC transporter
ASE18_RS14770	COG0530	calcium, potassium:sodium antiporter activity
ASE18_RS14775	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ASE18_RS14775	COG0517	IMP dehydrogenase activity
ASE18_RS14780	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ASE18_RS14785	COG3117	lipopolysaccharide transmembrane transporter activity
ASE18_RS14790	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ASE18_RS14795	COG1137	ATPase activity
ASE18_RS14800	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ASE18_RS14805	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ASE18_RS14820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASE18_RS14825	COG0515	serine threonine protein kinase
ASE18_RS14835	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ASE18_RS14840	COG0784	Response regulator, receiver
ASE18_RS14840	COG2198	Histidine kinase
ASE18_RS14840	COG5002	protein histidine kinase activity
ASE18_RS14845	COG1242	4 iron, 4 sulfur cluster binding
ASE18_RS14850	COG0067	glutamate synthase
ASE18_RS14850	COG0069	glutamate synthase activity
ASE18_RS14850	COG0070	glutamate synthase
ASE18_RS14855	COG0493	'glutamate synthase
ASE18_RS14860	COG4804	nuclease activity
ASE18_RS14865	COG2731	YhcH YjgK YiaL family protein
ASE18_RS14895	COG3069	C4-dicarboxylate transmembrane transporter activity
ASE18_RS14900	COG2969	positive regulation of protein catabolic process
ASE18_RS14905	COG0625	glutathione transferase activity
ASE18_RS14920	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ASE18_RS14925	COG3105	Protein conserved in bacteria
ASE18_RS14930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASE18_RS14935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASE18_RS14955	COG2732	(Barnase) inhibitor
ASE18_RS14975	COG0583	DNA-binding transcription factor activity
ASE18_RS14980	COG0312	modulator of DNA gyrase
ASE18_RS14985	COG3164	Protein of unknown function
ASE18_RS14990	COG1530	ribonuclease E activity
ASE18_RS15000	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ASE18_RS15005	COG1792	Involved in formation and maintenance of cell shape
ASE18_RS15010	COG1077	Cell shape determining protein MreB Mrl
ASE18_RS15020	COG2200	EAL domain
ASE18_RS15020	COG2199	diguanylate cyclase activity
ASE18_RS15025	COG0604	alcohol dehydrogenase
ASE18_RS15045	COG0511	ligase activity, forming carbon-carbon bonds
ASE18_RS15050	COG0439	Biotin carboxylase
ASE18_RS15055	COG3924	membrane
ASE18_RS15060	COG4145	pantothenate transmembrane transporter activity
ASE18_RS15070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASE18_RS15080	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ASE18_RS15090	COG1309	transcriptional regulator
ASE18_RS15095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASE18_RS15100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASE18_RS15115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASE18_RS15120	COG4597	amino acid ABC transporter
ASE18_RS15125	COG0765	amino acid transport
ASE18_RS15130	COG1126	abc transporter atp-binding protein
ASE18_RS15170	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ASE18_RS15190	COG0551	DNA topoisomerase type I activity
ASE18_RS15200	COG0758	DNA mediated transformation
ASE18_RS15220	COG0569	domain protein
ASE18_RS15230	COG3036	rescue of stalled ribosome
ASE18_RS15235	COG0789	Transcriptional regulator
ASE18_RS15275	COG0201	protein transport
ASE18_RS15365	COG0089	rRNA binding
ASE18_RS15390	COG3267	Type II secretory pathway component ExeA
ASE18_RS15390	COG3409	Peptidoglycan-binding domain 1 protein
ASE18_RS15400	COG3031	protein transport across the cell outer membrane
ASE18_RS15405	COG1450	Type ii and iii secretion system protein
ASE18_RS15410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASE18_RS15415	COG1459	type II secretion system
ASE18_RS15420	COG2165	general secretion pathway protein
ASE18_RS15425	COG2165	general secretion pathway protein
ASE18_RS15430	COG2165	general secretion pathway protein
ASE18_RS15435	COG4795	General secretion pathway protein
ASE18_RS15440	COG3156	type II secretion system protein K
ASE18_RS15445	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ASE18_RS15450	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ASE18_RS15455	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ASE18_RS15460	COG2193	ferroxidase activity
ASE18_RS15465	COG2906	2 iron, 2 sulfur cluster binding
ASE18_RS15470	COG3979	chitinase
ASE18_RS15510	COG2964	Protein conserved in bacteria
ASE18_RS15515	COG0545	Peptidyl-prolyl cis-trans isomerase
ASE18_RS15525	COG1047	Peptidyl-prolyl cis-trans
ASE18_RS15530	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ASE18_RS15545	COG0488	(ABC) transporter
ASE18_RS15550	COG0429	hydrolase of the alpha beta-hydrolase fold
ASE18_RS15560	COG3954	Phosphoribulokinase
ASE18_RS15565	COG1765	OsmC-like protein
ASE18_RS15575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASE18_RS15580	COG1289	transmembrane transporter activity
ASE18_RS15585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASE18_RS15590	COG0512	Glutamine amidotransferase of anthranilate synthase
ASE18_RS15595	COG2184	nucleotidyltransferase activity
ASE18_RS15605	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ASE18_RS15615	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASE18_RS15620	COG2146	nitrite reductase [NAD(P)H] activity
ASE18_RS15625	COG2116	formate transmembrane transporter activity
ASE18_RS15640	COG0531	amino acid
ASE18_RS15645	COG2222	sugar isomerase
ASE18_RS15650	COG1082	Xylose isomerase domain protein TIM barrel
ASE18_RS15660	COG2188	Transcriptional regulator
ASE18_RS15665	COG0626	cystathionine gamma-synthase activity
ASE18_RS15680	COG1735	metal-dependent hydrolase with the TIM-barrel fold
ASE18_RS15685	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ASE18_RS15690	COG3457	Alanine racemase
ASE18_RS15700	COG2188	Transcriptional regulator
ASE18_RS15705	COG0180	Tryptophanyl-tRNA synthetase
ASE18_RS15710	COG0546	phosphoglycolate phosphatase activity
ASE18_RS15715	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ASE18_RS15720	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ASE18_RS15725	COG3266	domain, Protein
ASE18_RS15740	COG4796	Type ii and iii secretion system protein
ASE18_RS15755	COG3166	PFAM Fimbrial assembly family protein
ASE18_RS15760	COG4972	Pilus assembly protein
ASE18_RS15765	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ASE18_RS15770	COG0494	nUDIX hydrolase
ASE18_RS15780	COG1011	Hydrolase
ASE18_RS15785	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ASE18_RS15795	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ASE18_RS15820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASE18_RS15825	COG2183	response to ionizing radiation
ASE18_RS15830	COG1918	ferrous iron import across plasma membrane
ASE18_RS15835	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ASE18_RS15845	COG5464	transposase or invertase
ASE18_RS15865	COG2610	gluconate transmembrane transporter activity
ASE18_RS15870	COG1640	4-alpha-glucanotransferase
ASE18_RS15875	COG0058	SHG alpha-glucan phosphorylase activity
ASE18_RS15890	COG1690	Belongs to the RtcB family
ASE18_RS15895	COG4650	regulator
ASE18_RS15900	COG1349	DNA-binding transcription factor activity
ASE18_RS15915	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ASE18_RS15935	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ASE18_RS15940	COG0058	SHG alpha-glucan phosphorylase activity
ASE18_RS15965	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASE18_RS15970	COG2095	MarC family integral membrane protein
ASE18_RS15975	COG2610	gluconate transmembrane transporter activity
ASE18_RS15980	COG3265	gluconokinase activity
ASE18_RS15985	COG1609	Transcriptional regulator
ASE18_RS15990	COG1741	Belongs to the pirin family
ASE18_RS15995	COG0673	inositol 2-dehydrogenase activity
ASE18_RS16000	COG1247	-acetyltransferase
ASE18_RS16010	COG0405	Gamma-glutamyltransferase
ASE18_RS16020	COG0584	glycerophosphoryl diester phosphodiesterase
ASE18_RS16030	COG0395	ABC-type sugar transport system, permease component
ASE18_RS16035	COG1175	transmembrane transport
ASE18_RS16040	COG1653	transport
ASE18_RS16050	COG0410	ABC transporter
ASE18_RS16055	COG0411	ABC transporter
ASE18_RS16060	COG4177	L-phenylalanine transmembrane transporter activity
ASE18_RS16065	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASE18_RS16070	COG0683	leucine binding
ASE18_RS16075	COG0456	acetyltransferase
ASE18_RS16090	COG0683	leucine binding
ASE18_RS16095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASE18_RS16100	COG2177	Part of the ABC transporter FtsEX involved in
ASE18_RS16105	COG2884	Cell division ATP-binding protein ftsE
ASE18_RS16110	COG0552	protein localization to endoplasmic reticulum
ASE18_RS16115	COG0742	ribosomal rna small subunit methyltransferase
ASE18_RS16120	COG3776	membrane
ASE18_RS16130	COG3714	YhhN family
ASE18_RS16145	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ASE18_RS16160	COG0628	permease
ASE18_RS16165	COG2091	lysine biosynthetic process via aminoadipic acid
ASE18_RS16170	COG0747	negative chemotaxis
ASE18_RS16175	COG0601	transmembrane transport
ASE18_RS16180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASE18_RS16185	COG0444	Belongs to the ABC transporter superfamily
ASE18_RS16210	COG0842	Transport permease protein
ASE18_RS16215	COG0842	Transport permease protein
ASE18_RS16215	COG1129	ABC transporter
ASE18_RS16220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASE18_RS16255	COG2205	protein histidine kinase activity
ASE18_RS16260	COG0745	RESPONSE REGULATOR receiver
ASE18_RS16265	COG1276	copper resistance
ASE18_RS16270	COG2372	response to copper ion
ASE18_RS16275	COG3667	copper resistance
ASE18_RS16280	COG2132	Multicopper oxidase
ASE18_RS16295	COG0739	heme binding
ASE18_RS16325	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASE18_RS16385	COG2801	Transposase and inactivated derivatives
ASE18_RS16405	COG2081	HI0933 family
ASE18_RS16410	COG0306	phosphate transporter
ASE18_RS16420	COG0589	response to stress
ASE18_RS16425	COG3104	oligopeptide transport
ASE18_RS16435	COG0339	signal peptide processing
ASE18_RS16440	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ASE18_RS16445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASE18_RS16460	COG0640	Transcriptional regulator
ASE18_RS16465	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ASE18_RS16470	COG1393	Belongs to the ArsC family
ASE18_RS16480	COG3065	identical protein binding
ASE18_RS16485	COG2197	response regulator
ASE18_RS16490	COG1285	pathogenesis
ASE18_RS16505	COG3247	response to pH
ASE18_RS16510	COG2771	luxR family
ASE18_RS16520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASE18_RS16525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASE18_RS16530	COG2207	Transcriptional regulator
ASE18_RS16540	COG0076	glutamate decarboxylase activity
ASE18_RS16545	COG1858	cytochrome C peroxidase
ASE18_RS16555	COG2197	response regulator
ASE18_RS16560	COG0583	DNA-binding transcription factor activity
ASE18_RS16565	COG1295	ribonuclease BN
ASE18_RS16570	COG0477	Major facilitator Superfamily
ASE18_RS16575	COG2982	Protein involved in outer membrane biogenesis
ASE18_RS16580	COG2200	EAL domain
ASE18_RS16595	COG0612	Peptidase, M16
ASE18_RS16605	COG2200	EAL domain
ASE18_RS16605	COG2199	diguanylate cyclase activity
ASE18_RS16610	COG0457	Tetratricopeptide repeat
ASE18_RS16610	COG3118	belongs to the thioredoxin family
ASE18_RS16615	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ASE18_RS16620	COG1215	transferase activity, transferring glycosyl groups
ASE18_RS16625	COG1215	transferase activity, transferring glycosyl groups
ASE18_RS16650	COG2194	sulfuric ester hydrolase activity
ASE18_RS16680	COG0814	amino acid
ASE18_RS16685	COG4608	Belongs to the ABC transporter superfamily
ASE18_RS16690	COG0444	Belongs to the ABC transporter superfamily
ASE18_RS16695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASE18_RS16700	COG0601	transmembrane transport
ASE18_RS16710	COG0747	negative chemotaxis
ASE18_RS16720	COG2194	sulfuric ester hydrolase activity
ASE18_RS16725	COG2223	nitrite transmembrane transporter activity
ASE18_RS16730	COG5571	outer membrane autotransporter
ASE18_RS16735	COG2818	Glycosylase
ASE18_RS16740	COG0456	acetyltransferase
ASE18_RS16745	COG0243	molybdopterin cofactor binding
ASE18_RS16750	COG2885	chlorophyll binding
ASE18_RS16765	COG2944	sequence-specific DNA binding
ASE18_RS16770	COG1278	Cold shock
ASE18_RS16795	COG3274	enterobacterial common antigen metabolic process
ASE18_RS16800	COG4682	membrane
ASE18_RS16805	COG4682	membrane
ASE18_RS16810	COG1070	Carbohydrate kinase
ASE18_RS16820	COG4213	ABC transporter substrate-binding protein
ASE18_RS16825	COG1129	ABC transporter
ASE18_RS16830	COG4214	carbohydrate transport
ASE18_RS16835	COG1609	Transcriptional regulator
ASE18_RS16835	COG2207	Transcriptional regulator
ASE18_RS16840	COG2992	FlgJ-related protein
ASE18_RS16845	COG0366	Alpha amylase catalytic
ASE18_RS16850	COG3977	Valine--pyruvate aminotransferase
ASE18_RS16860	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ASE18_RS16865	COG1414	Transcriptional regulator
ASE18_RS16875	COG2731	YhcH YjgK YiaL family protein
ASE18_RS16880	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASE18_RS16885	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASE18_RS16890	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASE18_RS16895	COG1070	Carbohydrate kinase
ASE18_RS16900	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ASE18_RS16905	COG3623	hexulose-6-phosphate isomerase
ASE18_RS16910	COG0235	Class ii aldolase
ASE18_RS16915	COG3713	MltA-interacting MipA family protein
ASE18_RS16920	COG0583	DNA-binding transcription factor activity
ASE18_RS16925	COG1566	PFAM secretion protein HlyD family protein
ASE18_RS16940	COG1012	belongs to the aldehyde dehydrogenase family
ASE18_RS16945	COG1454	alcohol dehydrogenase
ASE18_RS16950	COG3276	selenocysteine insertion sequence binding
ASE18_RS16960	COG0625	glutathione transferase activity
ASE18_RS16965	COG3209	COG3209 Rhs family protein
ASE18_RS16975	COG3209	COG3209 Rhs family protein
ASE18_RS16980	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ASE18_RS16990	COG1566	PFAM secretion protein HlyD family protein
ASE18_RS17000	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASE18_RS17000	COG2213	PTS system mannitol-specific
ASE18_RS17010	COG3722	fumarate hydratase activity
ASE18_RS17030	COG5295	Hep Hag repeat protein
ASE18_RS17035	COG1620	l-lactate permease
ASE18_RS17040	COG2186	Transcriptional regulator
ASE18_RS17050	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ASE18_RS17055	COG1045	serine acetyltransferase
ASE18_RS17070	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ASE18_RS17075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASE18_RS17085	COG4942	peptidase
ASE18_RS17090	COG2861	carbohydrate metabolic process
ASE18_RS17095	COG1216	Glycosyl transferase, family 2
ASE18_RS17100	COG1662	PFAM IS1 transposase
ASE18_RS17105	COG1216	Glycosyl transferase, family 2
ASE18_RS17115	COG0156	8-amino-7-oxononanoate synthase activity
ASE18_RS17125	COG0859	PFAM glycosyl transferase family 9
ASE18_RS17130	COG0859	PFAM glycosyl transferase family 9
ASE18_RS17135	COG3307	-O-antigen
ASE18_RS17140	COG1216	Glycosyl transferase, family 2
ASE18_RS17145	COG1442	glycosyl transferase family 8
ASE18_RS17150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASE18_RS17165	COG0515	serine threonine protein kinase
ASE18_RS17170	COG0438	transferase activity, transferring glycosyl groups
ASE18_RS17175	COG0859	PFAM glycosyl transferase family 9
ASE18_RS17180	COG1519	Transferase
ASE18_RS17210	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ASE18_RS17240	COG1561	YicC-like family, N-terminal region
ASE18_RS17245	COG3645	SOS response
ASE18_RS17250	COG2860	membrane
ASE18_RS17265	COG0194	GDP metabolic process
ASE18_RS17275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASE18_RS17280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASE18_RS17285	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ASE18_RS17295	COG0786	glutamate:sodium symporter activity
ASE18_RS17300	COG2233	PERMEase
ASE18_RS17305	COG2982	Protein involved in outer membrane biogenesis
ASE18_RS17310	COG1501	Belongs to the glycosyl hydrolase 31 family
ASE18_RS17315	COG2211	Major facilitator Superfamily
ASE18_RS17330	COG2814	Major facilitator Superfamily
ASE18_RS17335	COG0697	spore germination
ASE18_RS17340	COG1464	Belongs to the NlpA lipoprotein family
ASE18_RS17365	COG2252	PERMEase
ASE18_RS17375	COG2271	Major facilitator Superfamily
ASE18_RS17380	COG2271	Major facilitator Superfamily
ASE18_RS17385	COG3851	Histidine kinase
ASE18_RS17390	COG2197	response regulator
ASE18_RS17395	COG0440	acetolactate synthase activity
ASE18_RS17400	COG0028	Belongs to the TPP enzyme family
ASE18_RS17420	COG2814	Major facilitator Superfamily
ASE18_RS17425	COG0641	radical SAM
ASE18_RS17435	COG2149	membrane
ASE18_RS17445	COG3119	arylsulfatase activity
ASE18_RS17450	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASE18_RS17455	COG2207	Transcriptional regulator
ASE18_RS17470	COG2188	Transcriptional regulator
ASE18_RS17490	COG5645	(Lipo)protein
ASE18_RS17495	COG0823	Involved in the tonB-independent uptake of proteins
ASE18_RS17505	COG2271	Major facilitator Superfamily
ASE18_RS17510	COG2271	Major facilitator Superfamily
ASE18_RS17520	COG0800	Aldolase
ASE18_RS17525	COG3734	2-keto-3-deoxy-galactonokinase
ASE18_RS17530	COG2186	Transcriptional regulator
ASE18_RS17540	COG0561	phosphatase activity
ASE18_RS17545	COG3753	Protein conserved in bacteria
ASE18_RS17555	COG0187	DNA topoisomerase II activity
ASE18_RS17565	COG0592	DNA-directed DNA polymerase activity
ASE18_RS17610	COG0814	amino acid
ASE18_RS17625	COG2091	lysine biosynthetic process via aminoadipic acid
ASE18_RS17630	COG0431	NADPH-dependent FMN reductase
ASE18_RS17635	COG2252	PERMEase
ASE18_RS17640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASE18_RS17650	COG3196	Protein conserved in bacteria
ASE18_RS17655	COG0363	glucosamine-6-phosphate deaminase activity
ASE18_RS17660	COG2382	esterase
ASE18_RS17670	COG2723	6-phospho-beta-galactosidase activity
ASE18_RS17675	COG1263	PTS System
ASE18_RS17675	COG2190	(PTS) system
ASE18_RS17675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASE18_RS17680	COG3711	transcriptional antiterminator
ASE18_RS17685	COG0704	Plays a role in the regulation of phosphate uptake
ASE18_RS17690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASE18_RS17695	COG0581	inorganic phosphate transmembrane transporter activity
ASE18_RS17700	COG0573	inorganic phosphate transmembrane transporter activity
ASE18_RS17705	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ASE18_RS17715	COG3188	usher protein
ASE18_RS17725	COG3677	Transposase
ASE18_RS17725	COG1662	PFAM IS1 transposase
ASE18_RS17730	COG3121	Chaperone
ASE18_RS17740	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ASE18_RS17790	COG3312	ion transport
ASE18_RS17805	COG0716	FMN binding
ASE18_RS17810	COG1522	sequence-specific DNA binding
ASE18_RS17845	COG1172	Belongs to the binding-protein-dependent transport system permease family
ASE18_RS17850	COG1879	ABC-type sugar transport system periplasmic component
ASE18_RS17855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASE18_RS17860	COG1609	Transcriptional regulator
ASE18_RS17865	COG0477	Major facilitator Superfamily
ASE18_RS17870	COG2186	Transcriptional regulator
ASE18_RS17910	COG3085	chromosome segregation
ASE18_RS17915	COG0606	chelatase, subunit chli
ASE18_RS17930	COG3978	acetolactate synthase activity
ASE18_RS17935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASE18_RS17945	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ASE18_RS17950	COG0583	DNA-binding transcription factor activity
ASE18_RS17960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASE18_RS17965	COG3692	DNA binding
ASE18_RS17970	COG0210	DNA helicase
ASE18_RS17985	COG3118	belongs to the thioredoxin family
ASE18_RS17995	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ASE18_RS18005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ASE18_RS18010	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ASE18_RS18015	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ASE18_RS18020	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ASE18_RS18025	COG1088	dTDP-glucose 4,6-dehydratase activity
ASE18_RS18030	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ASE18_RS18035	COG0456	acetyltransferase
ASE18_RS18040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ASE18_RS18045	COG2244	polysaccharide biosynthetic process
ASE18_RS18065	COG1113	amino acid transport
ASE18_RS18090	COG0641	radical SAM
ASE18_RS18095	COG3119	arylsulfatase activity
ASE18_RS18100	COG3071	HemY protein
ASE18_RS18105	COG2959	enzyme of heme biosynthesis
ASE18_RS18110	COG1587	Uroporphyrinogen-III synthase
ASE18_RS18120	COG3072	Adenylate cyclase
ASE18_RS18130	COG5567	small periplasmic lipoprotein
ASE18_RS18140	COG3159	Protein conserved in bacteria
ASE18_RS18150	COG1011	Hydrolase
ASE18_RS18155	COG0210	DNA helicase
ASE18_RS18160	COG3698	Phosphodiester glycosidase
ASE18_RS18170	COG0598	Magnesium transport protein CorA
ASE18_RS18185	COG2962	Rard protein
ASE18_RS18190	COG2050	protein possibly involved in aromatic compounds catabolism
ASE18_RS18195	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
ASE18_RS18200	COG0514	ATP-dependent DNA helicase (RecQ)
ASE18_RS18205	COG1280	lysine exporter protein (LysE YggA)
ASE18_RS18210	COG1280	lysine exporter protein (LysE YggA)
ASE18_RS18215	COG2267	carboxylic ester hydrolase activity
ASE18_RS18220	COG0561	phosphatase activity
ASE18_RS18225	COG0697	spore germination
ASE18_RS18230	COG0583	DNA-binding transcription factor activity
ASE18_RS18240	COG0412	Dienelactone hydrolase
ASE18_RS18245	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ASE18_RS18250	COG1322	Protein conserved in bacteria
ASE18_RS18260	COG3165	ubiquinone biosynthetic process from chorismate
ASE18_RS18270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASE18_RS18275	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASE18_RS18280	COG0805	protein transport
ASE18_RS18290	COG0084	hydrolase, TatD family'
ASE18_RS18295	COG0250	Participates in transcription elongation, termination and antitermination
ASE18_RS18300	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ASE18_RS18305	COG0543	2 iron, 2 sulfur cluster binding
ASE18_RS18325	COG1739	Uncharacterized protein family UPF0029
ASE18_RS18330	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASE18_RS18335	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ASE18_RS18365	COG1763	Mo-molybdopterin cofactor biosynthetic process
ASE18_RS18370	COG0746	molybdenum cofactor guanylyltransferase activity
ASE18_RS18375	COG3084	Protein conserved in bacteria
ASE18_RS18380	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ASE18_RS18385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASE18_RS18390	COG5339	Protein conserved in bacteria
ASE18_RS18395	COG0204	Acyl-transferase
ASE18_RS18405	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASE18_RS18405	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ASE18_RS18420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASE18_RS18430	COG2204	response regulator
ASE18_RS18435	COG3852	Histidine kinase
ASE18_RS18445	COG0174	glutamine synthetase
ASE18_RS18455	COG1217	gtp-binding protein TYPA
ASE18_RS18460	COG2188	Transcriptional regulator
ASE18_RS18465	COG1082	Xylose isomerase domain protein TIM barrel
ASE18_RS18470	COG2271	Major facilitator Superfamily
ASE18_RS18475	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ASE18_RS18480	COG2211	Major facilitator Superfamily
ASE18_RS18485	COG2211	Major facilitator Superfamily
ASE18_RS18490	COG1501	Belongs to the glycosyl hydrolase 31 family
ASE18_RS18495	COG2017	converts alpha-aldose to the beta-anomer
ASE18_RS18500	COG2942	2-epimerase
ASE18_RS18505	COG3684	Belongs to the aldolase LacD family
ASE18_RS18510	COG2084	Dehydrogenase
ASE18_RS18515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASE18_RS18520	COG1349	DNA-binding transcription factor activity
ASE18_RS18525	COG1011	Hydrolase
ASE18_RS18540	COG0456	acetyltransferase
ASE18_RS18545	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ASE18_RS18550	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ASE18_RS18565	COG2864	formate dehydrogenase
ASE18_RS18570	COG0437	4 iron, 4 sulfur cluster binding
ASE18_RS18575	COG0243	molybdopterin cofactor binding
ASE18_RS18575	COG3383	formate dehydrogenase (NAD+) activity
ASE18_RS18580	COG0243	molybdopterin cofactor binding
ASE18_RS18580	COG3383	formate dehydrogenase (NAD+) activity
ASE18_RS18595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASE18_RS18595	COG3711	transcriptional antiterminator
ASE18_RS18600	COG1363	Peptidase, m42
ASE18_RS18605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASE18_RS18605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASE18_RS18610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASE18_RS18655	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ASE18_RS18670	COG2258	MOSC domain
ASE18_RS18675	COG2205	protein histidine kinase activity
ASE18_RS18680	COG0745	RESPONSE REGULATOR receiver
ASE18_RS18685	COG3678	ATP-independent chaperone mediated protein folding
ASE18_RS18700	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ASE18_RS18720	COG3152	Membrane
ASE18_RS18725	COG3691	Protein conserved in bacteria
ASE18_RS18730	COG0589	response to stress
ASE18_RS18740	COG1494	fructose-1,6-bisphosphatase
ASE18_RS18750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ASE18_RS18765	COG1575	Belongs to the MenA family. Type 1 subfamily
ASE18_RS18780	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ASE18_RS18785	COG1609	Transcriptional regulator
ASE18_RS18790	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ASE18_RS18800	COG3209	COG3209 Rhs family protein
ASE18_RS18840	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
ASE18_RS18850	COG0626	cystathionine gamma-synthase activity
ASE18_RS18855	COG0460	homoserine dehydrogenase
ASE18_RS18855	COG0527	aspartate kinase activity
ASE18_RS18865	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ASE18_RS18875	COG0697	spore germination
ASE18_RS18880	COG3738	Protein conserved in bacteria
ASE18_RS18890	COG0371	Dehydrogenase
ASE18_RS18895	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ASE18_RS18900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ASE18_RS18900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASE18_RS18900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASE18_RS18905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASE18_RS18910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASE18_RS18915	COG1882	Formate acetyltransferase
ASE18_RS18920	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ASE18_RS18925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASE18_RS18930	COG2207	Transcriptional regulator
ASE18_RS18935	COG2194	sulfuric ester hydrolase activity
ASE18_RS18950	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ASE18_RS18965	COG4948	Mandelate Racemase Muconate Lactonizing
ASE18_RS18970	COG2271	Major facilitator Superfamily
ASE18_RS18975	COG0583	DNA-binding transcription factor activity
ASE18_RS19035	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ASE18_RS19035	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ASE18_RS19075	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASE18_RS19080	COG0250	Participates in transcription elongation, termination and antitermination
ASE18_RS19120	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ASE18_RS19130	COG2104	thiamine diphosphate biosynthetic process
ASE18_RS19135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ASE18_RS19170	COG3068	Protein conserved in bacteria
ASE18_RS19185	COG3678	ATP-independent chaperone mediated protein folding
ASE18_RS19190	COG4191	Histidine kinase
ASE18_RS19195	COG2204	response regulator
ASE18_RS19200	COG0151	Belongs to the GarS family
ASE18_RS19245	COG0456	acetyltransferase
ASE18_RS19255	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ASE18_RS19260	COG2224	Isocitrate lyase
ASE18_RS19275	COG1414	Transcriptional regulator
ASE18_RS19280	COG1410	methionine synthase
ASE18_RS19280	COG0646	methionine synthase
ASE18_RS19285	COG1283	sodium-dependent phosphate transmembrane transporter activity
ASE18_RS19350	COG3541	Predicted nucleotidyltransferase
ASE18_RS19355	COG0542	response to heat
ASE18_RS19360	COG0527	aspartate kinase activity
ASE18_RS19385	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASE18_RS19405	COG0477	Major facilitator Superfamily
ASE18_RS19405	COG2814	Major facilitator Superfamily
ASE18_RS19410	COG3833	ABC-type maltose transport systems, permease component
ASE18_RS19415	COG1175	transmembrane transport
ASE18_RS19420	COG2182	Extracellular solute-binding protein
ASE18_RS19430	COG3842	ATPase activity
ASE18_RS19450	COG1357	PFAM Pentapeptide repeats (8 copies)
ASE18_RS19470	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ASE18_RS19480	COG0534	Mate efflux family protein
ASE18_RS19485	COG3237	CsbD-like
ASE18_RS19490	COG0735	belongs to the Fur family
ASE18_RS19545	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ASE18_RS19550	COG5532	Uncharacterized conserved protein (DUF2303)
ASE18_RS19590	COG1846	Transcriptional regulator
ASE18_RS19595	COG4725	Belongs to the MT-A70-like family
ASE18_RS19605	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ASE18_RS19615	COG1403	HNH endonuclease
ASE18_RS19620	COG0484	heat shock protein binding
ASE18_RS19635	COG3179	chitinase
ASE18_RS19660	COG4626	Terminase
ASE18_RS19660	COG1802	Transcriptional regulator
ASE18_RS19670	COG4695	Portal protein
ASE18_RS19715	COG4386	tail sheath protein
ASE18_RS19735	COG4228	DNA circulation
ASE18_RS19755	COG3299	homolog of phage Mu protein gp47
ASE18_RS19760	COG3778	Protein conserved in bacteria
ASE18_RS19770	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ASE18_RS19795	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASE18_RS19805	COG0604	alcohol dehydrogenase
ASE18_RS19810	COG0305	Participates in initiation and elongation during chromosome replication
ASE18_RS19815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASE18_RS19820	COG1448	Aminotransferase
ASE18_RS19830	COG3700	Belongs to the class B bacterial acid phosphatase family
ASE18_RS19835	COG0432	Pfam Uncharacterised protein family UPF0047
ASE18_RS19840	COG2315	Protein conserved in bacteria
ASE18_RS19845	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ASE18_RS19850	COG0629	single-stranded DNA binding
ASE18_RS19860	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ASE18_RS19870	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ASE18_RS19875	COG2207	Transcriptional regulator
ASE18_RS19880	COG0789	Transcriptional regulator
ASE18_RS19885	COG2252	PERMEase
ASE18_RS19890	COG0025	NhaP-type Na H and K H
ASE18_RS19895	COG1357	PFAM Pentapeptide repeats (8 copies)
ASE18_RS19905	COG3162	membrane
ASE18_RS19910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASE18_RS19920	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ASE18_RS19925	COG0437	4 iron, 4 sulfur cluster binding
ASE18_RS19930	COG3301	Polysulphide reductase, NrfD
ASE18_RS19935	COG1138	Cytochrome C-type biogenesis protein
ASE18_RS19940	COG3088	subunit of a heme lyase
ASE18_RS19945	COG4235	cytochrome complex assembly
ASE18_RS19950	COG1301	dicarboxylic acid transport
ASE18_RS19955	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ASE18_RS19960	COG3383	formate dehydrogenase (NAD+) activity
ASE18_RS19965	COG3383	formate dehydrogenase (NAD+) activity
ASE18_RS19975	COG1289	transmembrane transporter activity
ASE18_RS19980	COG1566	PFAM secretion protein HlyD family protein
ASE18_RS19990	COG2015	COG2015, Alkyl sulfatase and related hydrolases
ASE18_RS19995	COG1940	carbohydrate kinase activity
ASE18_RS20000	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ASE18_RS20005	COG1172	Belongs to the binding-protein-dependent transport system permease family
ASE18_RS20010	COG1129	ABC transporter
ASE18_RS20015	COG1879	ABC-type sugar transport system periplasmic component
ASE18_RS20020	COG1737	Transcriptional regulator
ASE18_RS20025	COG0698	ribose 5-phosphate isomerase
ASE18_RS20035	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ASE18_RS20040	COG0456	acetyltransferase
ASE18_RS20045	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
ASE18_RS20050	COG3454	Phosphonate metabolism
ASE18_RS20055	COG4778	phosphonate C-P lyase system protein PhnL
ASE18_RS20060	COG4107	phosphonate C-P lyase system protein PhnK
ASE18_RS20065	COG3627	carbon phosphorus lyase activity
ASE18_RS20070	COG3626	phosphonate metabolism
ASE18_RS20075	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ASE18_RS20080	COG3624	Phosphonate C-P lyase system protein PhnG
ASE18_RS20085	COG2188	Transcriptional regulator
ASE18_RS20090	COG3639	organic phosphonate transmembrane transporter activity
ASE18_RS20095	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ASE18_RS20105	COG2764	glyoxalase bleomycin resistance protein dioxygenase
ASE18_RS20110	COG2824	Alkylphosphonate utilization operon protein PhnA
ASE18_RS20125	COG0477	Major facilitator Superfamily
ASE18_RS20135	COG0642	Histidine kinase
ASE18_RS20140	COG0745	RESPONSE REGULATOR receiver
ASE18_RS20145	COG2194	sulfuric ester hydrolase activity
ASE18_RS20150	COG0531	amino acid
ASE18_RS20160	COG2207	Transcriptional regulator
ASE18_RS20165	COG1982	Orn Lys Arg decarboxylase major
ASE18_RS20170	COG2169	Transcriptional regulator
ASE18_RS20180	COG1486	melibiose metabolic process
ASE18_RS20190	COG2211	Major facilitator Superfamily
ASE18_RS20195	COG3647	Membrane
ASE18_RS20200	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ASE18_RS20200	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ASE18_RS20205	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ASE18_RS20215	COG4565	transcriptional regulatory protein
ASE18_RS20220	COG3290	protein histidine kinase activity
ASE18_RS20225	COG3592	Divergent 4Fe-4S mono-cluster
ASE18_RS20230	COG2388	GCN5-related N-acetyl-transferase
ASE18_RS20245	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ASE18_RS20250	COG3104	oligopeptide transport
ASE18_RS20255	COG1982	Orn Lys Arg decarboxylase major
ASE18_RS20260	COG0531	amino acid
ASE18_RS20265	COG3710	Transcriptional regulator
ASE18_RS20275	COG1309	transcriptional regulator
ASE18_RS20290	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ASE18_RS20295	COG1027	Aspartate ammonia-lyase
ASE18_RS20300	COG3030	protein affecting phage T7 exclusion by the F plasmid
ASE18_RS20305	COG0531	amino acid
ASE18_RS20330	COG1509	lysine 2,3-aminomutase activity
ASE18_RS20340	COG5510	response to toxic substance
ASE18_RS20345	COG5510	response to toxic substance
ASE18_RS20350	COG2076	Multidrug Resistance protein
ASE18_RS20355	COG3040	lipid binding
ASE18_RS20360	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ASE18_RS20375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ASE18_RS20380	COG1053	succinate dehydrogenase
ASE18_RS20390	COG0531	amino acid
ASE18_RS20405	COG1511	domain protein
ASE18_RS20405	COG3264	Mechanosensitive ion channel
ASE18_RS20440	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ASE18_RS20445	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ASE18_RS20445	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ASE18_RS20450	COG0802	atpase or kinase
ASE18_RS20455	COG0860	N-Acetylmuramoyl-L-alanine amidase
ASE18_RS20475	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ASE18_RS20480	COG0330	HflC and HflK could
ASE18_RS20485	COG0330	HflC and HflK could
ASE18_RS20490	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ASE18_RS20505	COG0557	exoribonuclease II activity
ASE18_RS20510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASE18_RS20515	COG3789	protein conserved in bacteria
ASE18_RS20520	COG1842	Phage shock protein A
ASE18_RS20530	COG3766	membrane
ASE18_RS20535	COG5463	Belongs to the UPF0441 family
ASE18_RS20540	COG0754	glutathionylspermidine amidase activity
ASE18_RS20545	COG1960	acyl-CoA dehydrogenase activity
ASE18_RS20555	COG3650	response to hydrogen peroxide
ASE18_RS20560	COG1073	alpha beta
ASE18_RS20575	COG3037	sugar-specific permease SgaT UlaA
ASE18_RS20580	COG3414	Phosphotransferase system galactitol-specific IIB component
ASE18_RS20625	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ASE18_RS20635	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASE18_RS20645	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASE18_RS20650	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ASE18_RS20655	COG4670	ketone body catabolic process
ASE18_RS20660	COG1024	Enoyl-CoA hydratase
ASE18_RS20670	COG1028	Short-chain dehydrogenase reductase Sdr
ASE18_RS20675	COG1309	transcriptional regulator
ASE18_RS20680	COG3061	Opacity-associated protein A
ASE18_RS20685	COG0545	Peptidyl-prolyl cis-trans isomerase
ASE18_RS20690	COG1113	amino acid transport
ASE18_RS20700	COG0697	spore germination
ASE18_RS20705	COG0702	epimerase
ASE18_RS20710	COG1733	regulation of RNA biosynthetic process
ASE18_RS20715	COG0737	Belongs to the 5'-nucleotidase family
ASE18_RS20720	COG1218	3'(2'),5'-bisphosphate nucleotidase
ASE18_RS20725	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ASE18_RS20735	COG1253	flavin adenine dinucleotide binding
ASE18_RS20750	COG0729	surface antigen
ASE18_RS20755	COG2911	Protein conserved in bacteria
ASE18_RS20760	COG2105	PFAM AIG2 family protein
ASE18_RS20765	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ASE18_RS20770	COG1879	ABC-type sugar transport system periplasmic component
ASE18_RS20775	COG1129	ABC transporter
ASE18_RS20780	COG1172	Belongs to the binding-protein-dependent transport system permease family
ASE18_RS20785	COG1172	Belongs to the binding-protein-dependent transport system permease family
ASE18_RS20795	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASE18_RS20805	COG0312	modulator of DNA gyrase
ASE18_RS20810	COG3783	Cytochrome b(562)
ASE18_RS20815	COG0602	queuosine metabolic process
ASE18_RS20820	COG1328	CTP reductase activity
ASE18_RS20825	COG0366	Alpha amylase catalytic
ASE18_RS20830	COG1263	PTS System
ASE18_RS20830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASE18_RS20835	COG1609	Transcriptional regulator
ASE18_RS20840	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ASE18_RS20845	COG0251	oxidation-reduction process
ASE18_RS20870	COG0251	oxidation-reduction process
ASE18_RS20875	COG1028	Short-chain dehydrogenase reductase Sdr
ASE18_RS20880	COG1309	transcriptional regulator
ASE18_RS20885	COG2731	YhcH YjgK YiaL family protein
ASE18_RS20900	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ASE18_RS20905	COG0456	acetyltransferase
ASE18_RS20910	COG4269	membrane
ASE18_RS20915	COG0525	valine-tRNA ligase activity
ASE18_RS20920	COG2927	DNA polymerase III (CHI subunit)
ASE18_RS20930	COG0795	lipopolysaccharide-transporting ATPase activity
ASE18_RS20935	COG0795	lipopolysaccharide-transporting ATPase activity
ASE18_RS20940	COG0433	COG0433 Predicted ATPase
ASE18_RS20945	COG1064	alcohol dehydrogenase
ASE18_RS21005	COG2963	transposase activity
ASE18_RS21010	COG2826	transposase and inactivated derivatives, IS30 family
ASE18_RS21020	COG2085	NADP oxidoreductase coenzyme F420-dependent
ASE18_RS21025	COG1120	ATPase activity
ASE18_RS21030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASE18_RS21035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASE18_RS21040	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ASE18_RS21045	COG4772	TonB-dependent receptor
ASE18_RS21050	COG3712	iron ion homeostasis
ASE18_RS21055	COG1595	DNA-templated transcription, initiation
ASE18_RS21085	COG4372	Transposase
ASE18_RS21090	COG3436	PFAM IS66 Orf2 family protein
ASE18_RS21150	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ASE18_RS21155	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ASE18_RS21175	COG0582	viral genome integration into host DNA
ASE18_RS21180	COG4974	Belongs to the 'phage' integrase family
ASE18_RS21195	COG3539	Fimbrial protein
ASE18_RS21200	COG3121	Chaperone
ASE18_RS21205	COG3188	usher protein
ASE18_RS21210	COG3539	Fimbrial protein
ASE18_RS21215	COG3539	Fimbrial protein
ASE18_RS21220	COG3539	Fimbrial protein
ASE18_RS21235	COG0246	Mannitol dehydrogenase
ASE18_RS21245	COG2186	Transcriptional regulator
ASE18_RS21270	COG0583	DNA-binding transcription factor activity
ASE18_RS21275	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ASE18_RS21280	COG0700	Nucleoside recognition
ASE18_RS21285	COG3366	ferrous iron transmembrane transporter activity
ASE18_RS21295	COG0477	Major facilitator Superfamily
ASE18_RS21310	COG1924	4 iron, 4 sulfur cluster binding
ASE18_RS21315	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
ASE18_RS21320	COG2733	membrane
ASE18_RS21325	COG2814	Major facilitator Superfamily
ASE18_RS21335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASE18_RS21340	COG5457	Domain of unknown function (DUF1127)
ASE18_RS21355	COG0523	cobalamin synthesis protein
ASE18_RS21360	COG2879	small protein
ASE18_RS21365	COG1966	Carbon starvation protein
ASE18_RS21375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ASE18_RS21380	COG2368	4-hydroxyphenylacetate
ASE18_RS21400	COG3971	2-oxopent-4-enoate hydratase activity
ASE18_RS21410	COG3384	dioxygenase
ASE18_RS21415	COG1012	belongs to the aldehyde dehydrogenase family
ASE18_RS21420	COG0179	Fumarylacetoacetate (FAA) hydrolase
ASE18_RS21425	COG1846	Transcriptional regulator
ASE18_RS21430	COG0840	transmembrane signaling receptor activity
ASE18_RS21435	COG2271	Major facilitator Superfamily
ASE18_RS21440	COG1802	Transcriptional regulator
ASE18_RS21445	COG1063	alcohol dehydrogenase
ASE18_RS21460	COG1484	DNA-dependent DNA replication
ASE18_RS21475	COG2966	Psort location CytoplasmicMembrane, score
ASE18_RS21480	COG2197	response regulator
ASE18_RS21485	COG2197	response regulator
ASE18_RS21490	COG4114	ferric iron reductase
ASE18_RS21520	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
ASE18_RS21525	COG0456	acetyltransferase
ASE18_RS21530	COG1011	Hydrolase
ASE18_RS21540	COG2823	Periplasmic or secreted lipoprotein
ASE18_RS21550	COG4667	esterase of the alpha-beta hydrolase superfamily
ASE18_RS21555	COG0084	hydrolase, TatD family'
ASE18_RS21560	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ASE18_RS21565	COG1328	CTP reductase activity
ASE18_RS21605	COG3726	membrane protein affecting hemolysin expression
ASE18_RS21610	COG0560	Phosphoserine phosphatase
ASE18_RS21615	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ASE18_RS21620	COG1056	cytidyltransferase-related domain
ASE18_RS21620	COG3172	ATPase kinase involved in NAD metabolism
ASE18_RS21630	COG0488	(ABC) transporter
ASE18_RS21635	COG0741	lytic transglycosylase activity
ASE18_RS21655	COG3708	Transcriptional regulator
ASE18_RS21655	COG2207	Transcriptional regulator
ASE18_RS21660	COG3045	CreA protein
ASE18_RS21665	COG0745	RESPONSE REGULATOR receiver
ASE18_RS21675	COG4452	Inner membrane protein CreD
ASE18_RS21680	COG0745	RESPONSE REGULATOR receiver
ASE18_RS21690	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ASE18_RS21700	COG0527	aspartate kinase activity
ASE18_RS21700	COG0460	homoserine dehydrogenase
ASE18_RS21710	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ASE18_RS21730	COG1115	amino acid carrier protein
ASE18_RS21735	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ASE18_RS21740	COG0521	Mo-molybdopterin cofactor biosynthetic process
ASE18_RS21745	COG1584	GPR1 FUN34 yaaH family protein
ASE18_RS21750	COG4735	regulation of single-species biofilm formation
ASE18_RS21785	COG0583	DNA-binding transcription factor activity
ASE18_RS21805	COG1662	PFAM IS1 transposase
ASE18_RS21810	COG3188	usher protein
ASE18_RS21830	COG0196	riboflavin kinase activity
ASE18_RS21845	COG1047	Peptidyl-prolyl cis-trans
ASE18_RS21875	COG0505	Belongs to the CarA family
ASE18_RS21880	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ASE18_RS21935	COG0644	oxidoreductase
ASE18_RS21945	COG2271	Major facilitator Superfamily
ASE18_RS21960	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ASE18_RS21985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASE18_RS21990	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ASE18_RS21995	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ASE18_RS22000	COG0564	pseudouridine synthase activity
ASE18_RS22010	COG0417	DNA replication proofreading
ASE18_RS22015	COG0235	Class ii aldolase
ASE18_RS22025	COG1069	ribulokinase activity
ASE18_RS22030	COG4977	sequence-specific DNA binding
ASE18_RS22035	COG0586	Pfam SNARE associated Golgi protein
ASE18_RS22045	COG1178	ABC-type Fe3 transport system permease component
ASE18_RS22050	COG4143	(ABC) transporter
ASE18_RS22065	COG2814	Major facilitator Superfamily
ASE18_RS22080	COG0473	3-isopropylmalate dehydrogenase activity
ASE18_RS22095	COG0583	DNA-binding transcription factor activity
ASE18_RS22100	COG0028	Belongs to the TPP enzyme family
ASE18_RS22105	COG0440	acetolactate synthase activity
ASE18_RS22115	COG1609	Transcriptional regulator
ASE18_RS22130	COG3116	cell division
ASE18_RS22135	COG0768	penicillin binding
ASE18_RS22140	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ASE18_RS22145	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ASE18_RS22155	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ASE18_RS22160	COG0772	Belongs to the SEDS family
ASE18_RS22175	COG1181	Belongs to the D-alanine--D-alanine ligase family
ASE18_RS22180	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ASE18_RS22185	COG0849	cell division
ASE18_RS22190	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ASE18_RS22210	COG0494	nUDIX hydrolase
ASE18_RS22230	COG0237	dephospho-CoA kinase activity
ASE18_RS22240	COG1459	type II secretion system
ASE18_RS22245	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASE18_RS22250	COG4969	Belongs to the N-Me-Phe pilin family
ASE18_RS22260	COG0157	Belongs to the NadC ModD family
ASE18_RS22265	COG3023	N-Acetylmuramoyl-L-alanine amidase
ASE18_RS22270	COG3725	Membrane protein required for beta-lactamase induction
ASE18_RS22275	COG1113	amino acid transport
ASE18_RS22280	COG2186	Transcriptional regulator
ASE18_RS22285	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ASE18_RS22290	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASE18_RS22295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASE18_RS22300	COG3064	Membrane
ASE18_RS22305	COG1049	propionate catabolic process, 2-methylcitrate cycle
ASE18_RS22330	COG2132	Multicopper oxidase
ASE18_RS22335	COG4993	Dehydrogenase
ASE18_RS22340	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ASE18_RS22345	COG0288	reversible hydration of carbon dioxide
ASE18_RS22350	COG1131	(ABC) transporter
ASE18_RS22355	COG0842	Transport permease protein
ASE18_RS22360	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASE18_RS22365	COG0726	polysaccharide deacetylase
ASE18_RS22375	COG5464	transposase or invertase
ASE18_RS22390	COG3539	Fimbrial protein
ASE18_RS22415	COG3539	Fimbrial protein
ASE18_RS22420	COG3539	Fimbrial protein
ASE18_RS22425	COG3539	Fimbrial protein
ASE18_RS22430	COG3539	Fimbrial protein
ASE18_RS22435	COG3188	usher protein
ASE18_RS22440	COG3121	Chaperone
ASE18_RS22445	COG3539	Fimbrial protein
ASE18_RS22450	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ASE18_RS22455	COG0617	tRNA 3'-terminal CCA addition
ASE18_RS22470	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ASE18_RS22480	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ASE18_RS22485	COG1643	Atp-dependent helicase
ASE18_RS22495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ASE18_RS22500	COG4774	siderophore transport
ASE18_RS22505	COG1120	ATPase activity
ASE18_RS22510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ASE18_RS22515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASE18_RS22535	COG2860	membrane
ASE18_RS22540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ASE18_RS22555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASE18_RS22560	COG3835	regulator
ASE18_RS22580	COG0024	Methionine aminopeptidase
ASE18_RS22605	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ASE18_RS22610	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ASE18_RS22615	COG0575	Belongs to the CDS family
ASE18_RS22620	COG0750	zinc metalloprotease
ASE18_RS22630	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ASE18_RS22635	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASE18_RS22660	COG0587	DNA-directed DNA polymerase activity
ASE18_RS22670	COG1982	Orn Lys Arg decarboxylase major
ASE18_RS22675	COG0346	lactoylglutathione lyase activity
ASE18_RS22685	COG4568	rho-dependent transcription termination
ASE18_RS22695	COG4681	YaeQ
ASE18_RS22700	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ASE18_RS22705	COG3015	lipoprotein NlpE involved in copper resistance
ASE18_RS22710	COG0791	NLP P60 protein
ASE18_RS22715	COG0791	NLP P60 protein
ASE18_RS22725	COG1720	tRNA m6t6A37 methyltransferase activity
ASE18_RS22735	COG1464	Belongs to the NlpA lipoprotein family
ASE18_RS22740	COG2011	ABC-type metal ion transport system permease component
ASE18_RS22745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ASE18_RS22750	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ASE18_RS22785	COG0656	L-ascorbic acid biosynthetic process
ASE18_RS22790	COG0583	DNA-binding transcription factor activity
ASE18_RS22805	COG0741	lytic transglycosylase activity
ASE18_RS22805	COG1388	LysM domain
ASE18_RS22815	COG2226	methyltransferase
ASE18_RS22825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASE18_RS22845	COG4104	PAAR repeat-containing protein
ASE18_RS22850	COG3157	Type VI secretion system effector, Hcp
ASE18_RS22865	COG3209	COG3209 Rhs family protein
ASE18_RS22880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASE18_RS22890	COG1960	acyl-CoA dehydrogenase activity
ASE18_RS22900	COG0121	glutamine amidotransferase
ASE18_RS22905	COG3034	peptidoglycan biosynthetic process
ASE18_RS22910	COG0791	NLP P60 protein
ASE18_RS22915	COG1943	Transposase
ASE18_RS22930	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ASE18_RS22935	COG0454	-acetyltransferase
ASE18_RS22940	COG1690	Belongs to the RtcB family
ASE18_RS22950	COG2195	Cleaves the N-terminal amino acid of tripeptides
ASE18_RS22970	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ASE18_RS22990	COG0582	viral genome integration into host DNA
ASE18_RS23005	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ASE18_RS23010	COG5532	Uncharacterized conserved protein (DUF2303)
ASE18_RS23045	COG4626	Terminase
ASE18_RS23045	COG1802	Transcriptional regulator
ASE18_RS23050	COG4725	Belongs to the MT-A70-like family
ASE18_RS23060	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ASE18_RS23070	COG1403	HNH endonuclease
ASE18_RS23110	COG2207	Transcriptional regulator
ASE18_RS23120	COG0583	DNA-binding transcription factor activity
ASE18_RS23125	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ASE18_RS23130	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ASE18_RS23135	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ASE18_RS23140	COG2080	2 iron, 2 sulfur cluster binding
ASE18_RS23145	COG3477	response to acidic pH
ASE18_RS23150	COG0727	PFAM Uncharacterised protein family (UPF0153)
ASE18_RS23155	COG3121	Chaperone
ASE18_RS23165	COG3188	usher protein
ASE18_RS23205	COG1388	LysM domain
ASE18_RS23210	COG2207	Transcriptional regulator
ASE18_RS23210	COG3708	Transcriptional regulator
ASE18_RS23215	COG3059	membrane
ASE18_RS23225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASE18_RS23230	COG2207	Transcriptional regulator
ASE18_RS23235	COG0247	lactate metabolic process
ASE18_RS23240	COG1139	Iron-sulfur cluster binding protein
ASE18_RS23245	COG1556	Lactate utilization protein
ASE18_RS23275	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASE18_RS23285	COG2771	luxR family
ASE18_RS23285	COG2200	EAL domain
ASE18_RS23290	COG0583	DNA-binding transcription factor activity
ASE18_RS23300	COG0666	response to abiotic stimulus
ASE18_RS23310	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ASE18_RS23315	COG1304	FMN binding
ASE18_RS23320	COG0549	Belongs to the carbamate kinase family
ASE18_RS23325	COG0402	S-adenosylhomocysteine deaminase activity
ASE18_RS23330	COG1064	alcohol dehydrogenase
ASE18_RS23345	COG1280	lysine exporter protein (LysE YggA)
ASE18_RS23355	COG3829	transcription factor binding
ASE18_RS23360	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ASE18_RS23365	COG0372	Belongs to the citrate synthase family
ASE18_RS23370	COG2079	MmgE PrpD family protein
ASE18_RS23375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASE18_RS23380	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ASE18_RS23385	COG0402	S-adenosylhomocysteine deaminase activity
ASE18_RS23390	COG0583	DNA-binding transcription factor activity
ASE18_RS23395	COG0288	reversible hydration of carbon dioxide
ASE18_RS23405	COG2807	transmembrane transport
ASE18_RS23410	COG0110	maltose O-acetyltransferase activity
ASE18_RS23415	COG2223	nitrite transmembrane transporter activity
ASE18_RS23425	COG1609	Transcriptional regulator
ASE18_RS23430	COG1414	Transcriptional regulator
ASE18_RS23465	COG2814	Major facilitator Superfamily
ASE18_RS23470	COG3122	Protein conserved in bacteria
ASE18_RS23500	COG1215	transferase activity, transferring glycosyl groups
ASE18_RS23505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ASE18_RS23510	COG4521	taurine ABC transporter
ASE18_RS23520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASE18_RS23525	COG2175	clavaminate synthase activity
ASE18_RS23530	COG0113	porphobilinogen synthase activity
ASE18_RS23550	COG3468	outer membrane autotransporter barrel domain protein
ASE18_RS23555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASE18_RS23560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ASE18_RS23570	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
ASE18_RS23595	COG1181	Belongs to the D-alanine--D-alanine ligase family
ASE18_RS23610	COG1785	Belongs to the alkaline phosphatase family
ASE18_RS23620	COG3706	GGDEF domain
ASE18_RS23625	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ASE18_RS23650	COG4126	flavin adenine dinucleotide binding
ASE18_RS23670	COG1940	carbohydrate kinase activity
ASE18_RS23675	COG2814	Major facilitator Superfamily
ASE18_RS23680	COG0419	ATPase involved in DNA repair
ASE18_RS23685	COG0420	3'-5' exonuclease activity
ASE18_RS23690	COG0745	RESPONSE REGULATOR receiver
ASE18_RS23695	COG5002	protein histidine kinase activity
ASE18_RS23700	COG1114	Component of the transport system for branched-chain amino acids
ASE18_RS23705	COG1113	amino acid transport
ASE18_RS23710	COG0366	Alpha amylase catalytic
ASE18_RS23730	COG1862	Preprotein translocase
ASE18_RS23735	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASE18_RS23740	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASE18_RS23745	COG1403	HNH endonuclease
ASE18_RS23755	COG3248	Nucleoside-binding outer membrane protein
ASE18_RS23760	COG4238	major outer membrane lipoprotein
ASE18_RS23770	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASE18_RS23770	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASE18_RS23785	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ASE18_RS23790	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ASE18_RS23795	COG0667	Aldo Keto reductase
ASE18_RS23805	COG0142	geranyltranstransferase activity
ASE18_RS23820	COG0693	protein deglycase activity
ASE18_RS23825	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ASE18_RS23835	COG2814	Major facilitator Superfamily
ASE18_RS23845	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ASE18_RS23850	COG1845	cytochrome c oxidase, subunit III
ASE18_RS23855	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ASE18_RS23860	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ASE18_RS23865	COG2223	nitrite transmembrane transporter activity
ASE18_RS23870	COG3056	Lipoprotein
ASE18_RS23875	COG0271	Belongs to the BolA IbaG family
ASE18_RS23900	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ASE18_RS23905	COG0776	regulation of translation
ASE18_RS23910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASE18_RS23915	COG1555	photosystem II stabilization
ASE18_RS23920	COG0824	Thioesterase
ASE18_RS23930	COG4533	DNA binding
ASE18_RS23940	COG1522	sequence-specific DNA binding
ASE18_RS23945	COG1132	(ABC) transporter
ASE18_RS23950	COG1132	(ABC) transporter
ASE18_RS23955	COG0347	Belongs to the P(II) protein family
ASE18_RS23960	COG0004	ammonium transporteR
ASE18_RS23965	COG1946	Acyl-CoA thioesterase
ASE18_RS23970	COG3126	Type III secretion system lipoprotein chaperone (YscW)
ASE18_RS23975	COG3695	enzyme binding
ASE18_RS23980	COG5507	3-demethylubiquinone-9 3-methyltransferase
ASE18_RS23985	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ASE18_RS23995	COG0110	maltose O-acetyltransferase activity
ASE18_RS24005	COG0110	maltose O-acetyltransferase activity
ASE18_RS24020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASE18_RS24025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASE18_RS24030	COG1309	transcriptional regulator
ASE18_RS24035	COG3264	Mechanosensitive ion channel
ASE18_RS24035	COG1196	nuclear chromosome segregation
ASE18_RS24050	COG3923	Primosomal replication protein n
ASE18_RS24055	COG2832	Protein of unknown function (DUF454)
ASE18_RS24065	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity