locus-tag	class	description
ICI43_RS00010	COG0592	DNA-directed DNA polymerase activity
ICI43_RS00020	COG0187	DNA topoisomerase II activity
ICI43_RS00025	COG3753	Protein conserved in bacteria
ICI43_RS00030	COG0561	phosphatase activity
ICI43_RS00040	COG2186	Transcriptional regulator
ICI43_RS00045	COG3734	2-keto-3-deoxy-galactonokinase
ICI43_RS00050	COG0800	Aldolase
ICI43_RS00060	COG2271	Major facilitator Superfamily
ICI43_RS00065	COG0644	oxidoreductase
ICI43_RS00070	COG0823	Involved in the tonB-independent uptake of proteins
ICI43_RS00075	COG5645	(Lipo)protein
ICI43_RS00095	COG2207	Transcriptional regulator
ICI43_RS00100	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ICI43_RS00105	COG3119	arylsulfatase activity
ICI43_RS00110	COG2149	membrane
ICI43_RS00120	COG0641	radical SAM
ICI43_RS00125	COG2814	Major facilitator Superfamily
ICI43_RS00135	COG0028	Belongs to the TPP enzyme family
ICI43_RS00140	COG0440	acetolactate synthase activity
ICI43_RS00150	COG2197	response regulator
ICI43_RS00155	COG3851	Histidine kinase
ICI43_RS00160	COG2271	Major facilitator Superfamily
ICI43_RS00165	COG2271	Major facilitator Superfamily
ICI43_RS00170	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ICI43_RS00175	COG2252	PERMEase
ICI43_RS00185	COG2814	Major facilitator Superfamily
ICI43_RS00195	COG1464	Belongs to the NlpA lipoprotein family
ICI43_RS00200	COG0697	spore germination
ICI43_RS00240	COG2003	Belongs to the UPF0758 family
ICI43_RS00270	COG3596	GTP binding
ICI43_RS00275	COG2378	regulation of single-species biofilm formation
ICI43_RS00305	COG0582	viral genome integration into host DNA
ICI43_RS00315	COG2211	Major facilitator Superfamily
ICI43_RS00320	COG1501	Belongs to the glycosyl hydrolase 31 family
ICI43_RS00325	COG3711	transcriptional antiterminator
ICI43_RS00330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICI43_RS00330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ICI43_RS00330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ICI43_RS00335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ICI43_RS00340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ICI43_RS00340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ICI43_RS00350	COG0191	fructose-bisphosphate aldolase activity
ICI43_RS00355	COG1940	carbohydrate kinase activity
ICI43_RS00365	COG2982	Protein involved in outer membrane biogenesis
ICI43_RS00370	COG2233	PERMEase
ICI43_RS00375	COG0786	glutamate:sodium symporter activity
ICI43_RS00380	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ICI43_RS00385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICI43_RS00390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ICI43_RS00400	COG0194	GDP metabolic process
ICI43_RS00405	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ICI43_RS00410	COG2860	membrane
ICI43_RS00415	COG3645	SOS response
ICI43_RS00420	COG1561	YicC-like family, N-terminal region
ICI43_RS00445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ICI43_RS00465	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ICI43_RS00475	COG1519	Transferase
ICI43_RS00480	COG0859	PFAM glycosyl transferase family 9
ICI43_RS00485	COG0438	transferase activity, transferring glycosyl groups
ICI43_RS00490	COG0515	serine threonine protein kinase
ICI43_RS00505	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ICI43_RS00510	COG1442	glycosyl transferase family 8
ICI43_RS00515	COG1216	Glycosyl transferase, family 2
ICI43_RS00520	COG3307	-O-antigen
ICI43_RS00525	COG0859	PFAM glycosyl transferase family 9
ICI43_RS00530	COG0859	PFAM glycosyl transferase family 9
ICI43_RS00540	COG0156	8-amino-7-oxononanoate synthase activity
ICI43_RS00550	COG1216	Glycosyl transferase, family 2
ICI43_RS00555	COG2861	carbohydrate metabolic process
ICI43_RS00560	COG4942	peptidase
ICI43_RS00570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ICI43_RS00575	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ICI43_RS00590	COG1045	serine acetyltransferase
ICI43_RS00595	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ICI43_RS00605	COG2186	Transcriptional regulator
ICI43_RS00610	COG1620	l-lactate permease
ICI43_RS00615	COG5295	Hep Hag repeat protein
ICI43_RS00635	COG3722	fumarate hydratase activity
ICI43_RS00645	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICI43_RS00645	COG2213	PTS system mannitol-specific
ICI43_RS00655	COG1566	PFAM secretion protein HlyD family protein
ICI43_RS00660	COG0625	glutathione transferase activity
ICI43_RS00670	COG3276	selenocysteine insertion sequence binding
ICI43_RS00675	COG1454	alcohol dehydrogenase
ICI43_RS00685	COG1012	belongs to the aldehyde dehydrogenase family
ICI43_RS00690	COG0235	Class ii aldolase
ICI43_RS00695	COG3623	hexulose-6-phosphate isomerase
ICI43_RS00700	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ICI43_RS00705	COG1070	Carbohydrate kinase
ICI43_RS00710	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ICI43_RS00715	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ICI43_RS00720	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ICI43_RS00730	COG2731	YhcH YjgK YiaL family protein
ICI43_RS00740	COG1414	Transcriptional regulator
ICI43_RS00745	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ICI43_RS00750	COG3977	Valine--pyruvate aminotransferase
ICI43_RS00755	COG0366	Alpha amylase catalytic
ICI43_RS00760	COG2992	FlgJ-related protein
ICI43_RS00765	COG1609	Transcriptional regulator
ICI43_RS00765	COG2207	Transcriptional regulator
ICI43_RS00770	COG4214	carbohydrate transport
ICI43_RS00780	COG4213	ABC transporter substrate-binding protein
ICI43_RS00790	COG1070	Carbohydrate kinase
ICI43_RS00795	COG4682	membrane
ICI43_RS00800	COG4682	membrane
ICI43_RS00805	COG3274	enterobacterial common antigen metabolic process
ICI43_RS00830	COG1278	Cold shock
ICI43_RS00835	COG2944	sequence-specific DNA binding
ICI43_RS00845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICI43_RS00850	COG2885	chlorophyll binding
ICI43_RS00855	COG0243	molybdopterin cofactor binding
ICI43_RS00860	COG0456	acetyltransferase
ICI43_RS00865	COG2818	Glycosylase
ICI43_RS00870	COG5571	outer membrane autotransporter
ICI43_RS00875	COG2223	nitrite transmembrane transporter activity
ICI43_RS00880	COG2194	sulfuric ester hydrolase activity
ICI43_RS00890	COG0747	negative chemotaxis
ICI43_RS00900	COG0601	transmembrane transport
ICI43_RS00905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICI43_RS00910	COG0444	Belongs to the ABC transporter superfamily
ICI43_RS00915	COG4608	Belongs to the ABC transporter superfamily
ICI43_RS00920	COG0814	amino acid
ICI43_RS00935	COG2194	sulfuric ester hydrolase activity
ICI43_RS00960	COG1215	transferase activity, transferring glycosyl groups
ICI43_RS00965	COG1215	transferase activity, transferring glycosyl groups
ICI43_RS00970	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ICI43_RS00975	COG0457	Tetratricopeptide repeat
ICI43_RS00975	COG3118	belongs to the thioredoxin family
ICI43_RS00980	COG2200	EAL domain
ICI43_RS00980	COG2199	diguanylate cyclase activity
ICI43_RS00990	COG0612	Peptidase, M16
ICI43_RS00995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICI43_RS01000	COG2200	EAL domain
ICI43_RS01005	COG2982	Protein involved in outer membrane biogenesis
ICI43_RS01010	COG0477	Major facilitator Superfamily
ICI43_RS01015	COG1295	ribonuclease BN
ICI43_RS01020	COG0583	DNA-binding transcription factor activity
ICI43_RS01025	COG2197	response regulator
ICI43_RS01035	COG1858	cytochrome C peroxidase
ICI43_RS01040	COG0076	glutamate decarboxylase activity
ICI43_RS01045	COG2207	Transcriptional regulator
ICI43_RS01050	COG2207	Transcriptional regulator
ICI43_RS01055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICI43_RS01060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICI43_RS01070	COG2771	luxR family
ICI43_RS01075	COG3247	response to pH
ICI43_RS01090	COG1285	pathogenesis
ICI43_RS01100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICI43_RS01110	COG3721	Heme iron utilization protein
ICI43_RS01125	COG4771	TonB-dependent receptor
ICI43_RS01130	COG3720	iron ion transport
ICI43_RS01135	COG2197	response regulator
ICI43_RS01140	COG3065	identical protein binding
ICI43_RS01150	COG1393	Belongs to the ArsC family
ICI43_RS01160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ICI43_RS01165	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ICI43_RS01170	COG0339	signal peptide processing
ICI43_RS01180	COG3104	oligopeptide transport
ICI43_RS01185	COG0589	response to stress
ICI43_RS01195	COG0306	phosphate transporter
ICI43_RS01200	COG2081	HI0933 family
ICI43_RS01210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICI43_RS01215	COG1129	ABC transporter
ICI43_RS01215	COG0842	Transport permease protein
ICI43_RS01220	COG0842	Transport permease protein
ICI43_RS01225	COG0191	fructose-bisphosphate aldolase activity
ICI43_RS01240	COG3775	system Galactitol-specific IIC component
ICI43_RS01245	COG3414	Phosphotransferase system galactitol-specific IIB component
ICI43_RS01255	COG2188	Transcriptional regulator
ICI43_RS01270	COG0444	Belongs to the ABC transporter superfamily
ICI43_RS01275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICI43_RS01280	COG0601	transmembrane transport
ICI43_RS01285	COG0747	negative chemotaxis
ICI43_RS01290	COG2091	lysine biosynthetic process via aminoadipic acid
ICI43_RS01295	COG0628	permease
ICI43_RS01300	COG0477	Major facilitator Superfamily
ICI43_RS01310	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ICI43_RS01325	COG3714	YhhN family
ICI43_RS01335	COG3776	membrane
ICI43_RS01340	COG0742	ribosomal rna small subunit methyltransferase
ICI43_RS01345	COG0552	protein localization to endoplasmic reticulum
ICI43_RS01350	COG2884	Cell division ATP-binding protein ftsE
ICI43_RS01355	COG2177	Part of the ABC transporter FtsEX involved in
ICI43_RS01360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICI43_RS01365	COG0683	leucine binding
ICI43_RS01370	COG0456	acetyltransferase
ICI43_RS01375	COG0683	leucine binding
ICI43_RS01380	COG0559	Belongs to the binding-protein-dependent transport system permease family
ICI43_RS01385	COG4177	L-phenylalanine transmembrane transporter activity
ICI43_RS01390	COG0411	ABC transporter
ICI43_RS01395	COG0410	ABC transporter
ICI43_RS01405	COG1175	transmembrane transport
ICI43_RS01415	COG3842	ATPase activity
ICI43_RS01420	COG0584	glycerophosphoryl diester phosphodiesterase
ICI43_RS01430	COG0405	Gamma-glutamyltransferase
ICI43_RS01450	COG3157	Type VI secretion system effector, Hcp
ICI43_RS01460	COG0673	inositol 2-dehydrogenase activity
ICI43_RS01465	COG1741	Belongs to the pirin family
ICI43_RS01470	COG1609	Transcriptional regulator
ICI43_RS01475	COG3265	gluconokinase activity
ICI43_RS01480	COG2610	gluconate transmembrane transporter activity
ICI43_RS01485	COG0514	ATP-dependent DNA helicase (RecQ)
ICI43_RS01495	COG2095	MarC family integral membrane protein
ICI43_RS01500	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ICI43_RS01505	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ICI43_RS01510	COG1523	belongs to the glycosyl hydrolase 13 family
ICI43_RS01525	COG0058	SHG alpha-glucan phosphorylase activity
ICI43_RS01535	COG3121	Chaperone
ICI43_RS01540	COG3188	usher protein
ICI43_RS01580	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ICI43_RS01595	COG1349	DNA-binding transcription factor activity
ICI43_RS01600	COG4650	regulator
ICI43_RS01605	COG1690	Belongs to the RtcB family
ICI43_RS01615	COG2909	trisaccharide binding
ICI43_RS01620	COG0058	SHG alpha-glucan phosphorylase activity
ICI43_RS01625	COG1640	4-alpha-glucanotransferase
ICI43_RS01630	COG2610	gluconate transmembrane transporter activity
ICI43_RS01640	COG1040	competence protein
ICI43_RS01645	COG0596	Alpha beta hydrolase
ICI43_RS01660	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ICI43_RS01665	COG1918	ferrous iron import across plasma membrane
ICI43_RS01670	COG2183	response to ionizing radiation
ICI43_RS01675	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ICI43_RS01700	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ICI43_RS01705	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ICI43_RS01715	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ICI43_RS01720	COG1011	Hydrolase
ICI43_RS01730	COG0494	nUDIX hydrolase
ICI43_RS01735	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ICI43_RS01740	COG4972	Pilus assembly protein
ICI43_RS01745	COG3166	PFAM Fimbrial assembly family protein
ICI43_RS01760	COG4796	Type ii and iii secretion system protein
ICI43_RS01775	COG3266	domain, Protein
ICI43_RS01780	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ICI43_RS01785	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ICI43_RS01790	COG0546	phosphoglycolate phosphatase activity
ICI43_RS01795	COG0180	Tryptophanyl-tRNA synthetase
ICI43_RS01800	COG2188	Transcriptional regulator
ICI43_RS01810	COG3457	Alanine racemase
ICI43_RS01815	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ICI43_RS01820	COG1735	metal-dependent hydrolase with the TIM-barrel fold
ICI43_RS01835	COG0626	cystathionine gamma-synthase activity
ICI43_RS01850	COG2116	formate transmembrane transporter activity
ICI43_RS01855	COG2146	nitrite reductase [NAD(P)H] activity
ICI43_RS01860	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ICI43_RS01870	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ICI43_RS01880	COG2184	nucleotidyltransferase activity
ICI43_RS01885	COG0512	Glutamine amidotransferase of anthranilate synthase
ICI43_RS01890	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ICI43_RS01895	COG1289	transmembrane transporter activity
ICI43_RS01900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ICI43_RS01905	COG1765	OsmC-like protein
ICI43_RS01910	COG3954	Phosphoribulokinase
ICI43_RS01920	COG0429	hydrolase of the alpha beta-hydrolase fold
ICI43_RS01925	COG0488	(ABC) transporter
ICI43_RS01940	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ICI43_RS01945	COG1047	Peptidyl-prolyl cis-trans
ICI43_RS01955	COG0545	Peptidyl-prolyl cis-trans isomerase
ICI43_RS01960	COG2964	Protein conserved in bacteria
ICI43_RS02000	COG3979	chitinase
ICI43_RS02005	COG2906	2 iron, 2 sulfur cluster binding
ICI43_RS02010	COG2193	ferroxidase activity
ICI43_RS02015	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ICI43_RS02020	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ICI43_RS02025	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ICI43_RS02035	COG4795	General secretion pathway protein
ICI43_RS02040	COG2165	general secretion pathway protein
ICI43_RS02045	COG2165	general secretion pathway protein
ICI43_RS02050	COG2165	general secretion pathway protein
ICI43_RS02055	COG1459	type II secretion system
ICI43_RS02060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ICI43_RS02065	COG1450	Type ii and iii secretion system protein
ICI43_RS02070	COG3031	protein transport across the cell outer membrane
ICI43_RS02075	COG3267	Type II secretory pathway component ExeA
ICI43_RS02075	COG3409	Peptidoglycan-binding domain 1 protein
ICI43_RS02100	COG0089	rRNA binding
ICI43_RS02190	COG0201	protein transport
ICI43_RS02230	COG0789	Transcriptional regulator
ICI43_RS02235	COG3036	rescue of stalled ribosome
ICI43_RS02245	COG0569	domain protein
ICI43_RS02250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ICI43_RS02250	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ICI43_RS02255	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ICI43_RS02265	COG0758	DNA mediated transformation
ICI43_RS02275	COG0551	DNA topoisomerase type I activity
ICI43_RS02280	COG0009	L-threonylcarbamoyladenylate synthase
ICI43_RS02285	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ICI43_RS02295	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ICI43_RS02335	COG1126	abc transporter atp-binding protein
ICI43_RS02340	COG0765	amino acid transport
ICI43_RS02345	COG4597	amino acid ABC transporter
ICI43_RS02350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICI43_RS02360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICI43_RS02365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICI43_RS02370	COG1309	transcriptional regulator
ICI43_RS02380	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ICI43_RS02390	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICI43_RS02400	COG4145	pantothenate transmembrane transporter activity
ICI43_RS02405	COG3924	membrane
ICI43_RS02410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICI43_RS02415	COG1349	DNA-binding transcription factor activity
ICI43_RS02425	COG1879	ABC-type sugar transport system periplasmic component
ICI43_RS02430	COG1129	ABC transporter
ICI43_RS02435	COG1172	Belongs to the binding-protein-dependent transport system permease family
ICI43_RS02440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICI43_RS02450	COG0439	Biotin carboxylase
ICI43_RS02455	COG0511	ligase activity, forming carbon-carbon bonds
ICI43_RS02460	COG0604	alcohol dehydrogenase
ICI43_RS02465	COG2199	diguanylate cyclase activity
ICI43_RS02465	COG2200	EAL domain
ICI43_RS02470	COG1077	Cell shape determining protein MreB Mrl
ICI43_RS02475	COG1792	Involved in formation and maintenance of cell shape
ICI43_RS02480	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ICI43_RS02490	COG1530	ribonuclease E activity
ICI43_RS02495	COG3164	Protein of unknown function
ICI43_RS02500	COG0312	modulator of DNA gyrase
ICI43_RS02505	COG0583	DNA-binding transcription factor activity
ICI43_RS02520	COG1289	transmembrane transporter activity
ICI43_RS02525	COG2732	(Barnase) inhibitor
ICI43_RS02545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ICI43_RS02550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ICI43_RS02555	COG3105	Protein conserved in bacteria
ICI43_RS02560	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ICI43_RS02575	COG0625	glutathione transferase activity
ICI43_RS02580	COG2969	positive regulation of protein catabolic process
ICI43_RS02595	COG2814	Major facilitator Superfamily
ICI43_RS02605	COG1940	carbohydrate kinase activity
ICI43_RS02610	COG2731	YhcH YjgK YiaL family protein
ICI43_RS02615	COG0493	'glutamate synthase
ICI43_RS02620	COG0067	glutamate synthase
ICI43_RS02620	COG0069	glutamate synthase activity
ICI43_RS02620	COG0070	glutamate synthase
ICI43_RS02625	COG1242	4 iron, 4 sulfur cluster binding
ICI43_RS02630	COG5002	protein histidine kinase activity
ICI43_RS02630	COG2198	Histidine kinase
ICI43_RS02630	COG0784	Response regulator, receiver
ICI43_RS02635	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ICI43_RS02645	COG0515	serine threonine protein kinase
ICI43_RS02650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICI43_RS02665	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ICI43_RS02670	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ICI43_RS02675	COG1137	ATPase activity
ICI43_RS02680	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ICI43_RS02685	COG3117	lipopolysaccharide transmembrane transporter activity
ICI43_RS02690	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ICI43_RS02695	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ICI43_RS02695	COG0517	IMP dehydrogenase activity
ICI43_RS02700	COG0530	calcium, potassium:sodium antiporter activity
ICI43_RS02705	COG1127	ABC transporter
ICI43_RS02710	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ICI43_RS02715	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ICI43_RS02720	COG2854	intermembrane phospholipid transfer
ICI43_RS02725	COG3113	response to antibiotic
ICI43_RS02730	COG5007	Belongs to the BolA IbaG family
ICI43_RS02740	COG3423	Transcriptional regulator
ICI43_RS02745	COG0142	geranyltranstransferase activity
ICI43_RS02760	COG0697	spore germination
ICI43_RS02770	COG2027	D-alanyl-D-alanine carboxypeptidase
ICI43_RS02775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ICI43_RS02780	COG1534	Rna-binding protein
ICI43_RS02790	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ICI43_RS02795	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ICI43_RS02805	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ICI43_RS02815	COG2194	sulfuric ester hydrolase activity
ICI43_RS02835	COG0195	Participates in both transcription termination and antitermination
ICI43_RS02875	COG0513	Belongs to the DEAD box helicase family
ICI43_RS02880	COG0814	amino acid
ICI43_RS02885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICI43_RS02890	COG0826	peptidase U32
ICI43_RS02895	COG0826	peptidase U32
ICI43_RS02900	COG3154	lipid carrier protein
ICI43_RS02905	COG3153	acetyltransferase
ICI43_RS02920	COG0702	epimerase
ICI43_RS02925	COG0701	Predicted permease
ICI43_RS02930	COG2823	Periplasmic or secreted lipoprotein
ICI43_RS02945	COG3107	peptidoglycan biosynthetic process
ICI43_RS02950	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ICI43_RS02955	COG0363	glucosamine-6-phosphate deaminase activity
ICI43_RS02960	COG3716	PTS system mannose fructose sorbose family IID component
ICI43_RS02965	COG3715	PTS system
ICI43_RS02970	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ICI43_RS02980	COG2222	sugar isomerase
ICI43_RS02985	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ICI43_RS02990	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICI43_RS02995	COG3716	PTS system mannose fructose sorbose family IID component
ICI43_RS03005	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ICI43_RS03015	COG1349	DNA-binding transcription factor activity
ICI43_RS03025	COG2002	toxin-antitoxin pair type II binding
ICI43_RS03030	COG2721	sulfolactate sulfo-lyase activity
ICI43_RS03035	COG2271	Major facilitator Superfamily
ICI43_RS03040	COG3836	Belongs to the HpcH HpaI aldolase family
ICI43_RS03045	COG2084	Dehydrogenase
ICI43_RS03050	COG1929	Belongs to the glycerate kinase type-1 family
ICI43_RS03065	COG0583	DNA-binding transcription factor activity
ICI43_RS03070	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ICI43_RS03080	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ICI43_RS03085	COG1882	Formate acetyltransferase
ICI43_RS03090	COG0251	oxidation-reduction process
ICI43_RS03095	COG1760	l-serine dehydratase
ICI43_RS03100	COG0814	amino acid
ICI43_RS03115	COG1741	Belongs to the pirin family
ICI43_RS03120	COG0583	DNA-binding transcription factor activity
ICI43_RS03125	COG3152	Membrane
ICI43_RS03130	COG0435	Glutathione S-transferase
ICI43_RS03135	COG2259	Doxx family
ICI43_RS03145	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
ICI43_RS03150	COG4575	ribosome binding
ICI43_RS03155	COG1422	Protein of unknown function (DUF1090)
ICI43_RS03165	COG0586	Pfam SNARE associated Golgi protein
ICI43_RS03170	COG2186	Transcriptional regulator
ICI43_RS03175	COG2271	Major facilitator Superfamily
ICI43_RS03185	COG2721	sulfolactate sulfo-lyase activity
ICI43_RS03195	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ICI43_RS03200	COG0861	Integral membrane protein TerC family
ICI43_RS03205	COG0673	inositol 2-dehydrogenase activity
ICI43_RS03210	COG2949	membrane
ICI43_RS03215	COG1451	nucleotide metabolic process
ICI43_RS03230	COG5499	transcription regulator containing HTH domain
ICI43_RS03235	COG1902	pentaerythritol trinitrate reductase activity
ICI43_RS03235	COG0446	pyridine nucleotide-disulphide oxidoreductase
ICI43_RS03240	COG3408	Glycogen debranching enzyme
ICI43_RS03240	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
ICI43_RS03250	COG0531	amino acid
ICI43_RS03255	COG2731	YhcH YjgK YiaL family protein
ICI43_RS03260	COG3250	beta-galactosidase activity
ICI43_RS03265	COG1609	Transcriptional regulator
ICI43_RS03270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ICI43_RS03275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ICI43_RS03280	COG0840	transmembrane signaling receptor activity
ICI43_RS03285	COG1695	Transcriptional regulator
ICI43_RS03290	COG2375	cellular response to nickel ion
ICI43_RS03305	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICI43_RS03310	COG0358	DNA primase activity
ICI43_RS03315	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ICI43_RS03330	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ICI43_RS03350	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ICI43_RS03360	COG0617	tRNA 3'-terminal CCA addition
ICI43_RS03365	COG4991	sh3 domain protein
ICI43_RS03370	COG0675	Transposase, IS605 OrfB family
ICI43_RS03380	COG3025	triphosphatase activity
ICI43_RS03385	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ICI43_RS03400	COG2268	Band 7 protein
ICI43_RS03405	COG1585	Membrane protein implicated in regulation of membrane protease activity
ICI43_RS03425	COG3539	Fimbrial protein
ICI43_RS03430	COG3121	Chaperone
ICI43_RS03435	COG3188	usher protein
ICI43_RS03440	COG3539	Fimbrial protein
ICI43_RS03455	COG3384	dioxygenase
ICI43_RS03465	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ICI43_RS03475	COG0754	glutathionylspermidine amidase activity
ICI43_RS03485	COG1538	Outer membrane efflux protein
ICI43_RS03490	COG0494	nUDIX hydrolase
ICI43_RS03495	COG3151	Protein conserved in bacteria
ICI43_RS03500	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ICI43_RS03505	COG3150	esterase
ICI43_RS03510	COG0187	DNA topoisomerase II activity
ICI43_RS03515	COG4774	siderophore transport
ICI43_RS03520	COG1120	ATPase activity
ICI43_RS03525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICI43_RS03530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICI43_RS03540	COG1737	Transcriptional regulator
ICI43_RS03545	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ICI43_RS03550	COG2249	NAD(P)H dehydrogenase (quinone) activity
ICI43_RS03565	COG0642	Histidine kinase
ICI43_RS03570	COG0745	RESPONSE REGULATOR receiver
ICI43_RS03575	COG3111	PFAM Bacterial OB fold (BOF) protein
ICI43_RS03580	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ICI43_RS03585	COG4166	transmembrane transport
ICI43_RS03590	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ICI43_RS03595	COG0204	Acyl-transferase
ICI43_RS03600	COG2132	Multicopper oxidase
ICI43_RS03620	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ICI43_RS03625	COG1063	alcohol dehydrogenase
ICI43_RS03630	COG0246	Mannitol dehydrogenase
ICI43_RS03635	COG2186	Transcriptional regulator
ICI43_RS03640	COG1032	radical SAM domain protein
ICI43_RS03645	COG4238	major outer membrane lipoprotein
ICI43_RS03655	COG0656	L-ascorbic acid biosynthetic process
ICI43_RS03660	COG1979	alcohol dehydrogenase
ICI43_RS03665	COG2207	Transcriptional regulator
ICI43_RS03670	COG0586	Pfam SNARE associated Golgi protein
ICI43_RS03675	COG0626	cystathionine gamma-synthase activity
ICI43_RS03680	COG0811	peptide transport
ICI43_RS03685	COG0848	biopolymer transport protein
ICI43_RS03690	COG1028	Short-chain dehydrogenase reductase Sdr
ICI43_RS03700	COG0667	Aldo Keto reductase
ICI43_RS03715	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ICI43_RS03720	COG0437	4 iron, 4 sulfur cluster binding
ICI43_RS03725	COG5557	Pfam Polysulphide reductase, NrfD
ICI43_RS03730	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ICI43_RS03735	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ICI43_RS03740	COG1773	rubredoxin
ICI43_RS03745	COG0375	protein maturation
ICI43_RS03750	COG0298	carbon dioxide binding
ICI43_RS03755	COG0625	glutathione transferase activity
ICI43_RS03760	COG0754	glutathionylspermidine amidase activity
ICI43_RS03765	COG0306	phosphate transporter
ICI43_RS03770	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ICI43_RS03775	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ICI43_RS03780	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ICI43_RS03785	COG2244	polysaccharide biosynthetic process
ICI43_RS03795	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ICI43_RS03800	COG0795	lipopolysaccharide-transporting ATPase activity
ICI43_RS03810	COG0156	8-amino-7-oxononanoate synthase activity
ICI43_RS03815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICI43_RS03825	COG0318	PFAM AMP-dependent synthetase and ligase
ICI43_RS03830	COG0456	acetyltransferase
ICI43_RS03835	COG2186	Transcriptional regulator
ICI43_RS03840	COG0277	FAD linked oxidase domain protein
ICI43_RS03845	COG0277	FAD linked oxidase domain protein
ICI43_RS03850	COG0247	lactate metabolic process
ICI43_RS03855	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ICI43_RS03860	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ICI43_RS03865	COG1620	l-lactate permease
ICI43_RS03870	COG3385	transposase activity
ICI43_RS03885	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ICI43_RS03900	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ICI43_RS03910	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ICI43_RS03950	COG0517	IMP dehydrogenase activity
ICI43_RS03950	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ICI43_RS04010	COG2003	Belongs to the UPF0758 family
ICI43_RS04035	COG2020	methyltransferase activity
ICI43_RS04045	COG3436	PFAM IS66 Orf2 family protein
ICI43_RS04055	COG2433	Pfam Transposase IS66
ICI43_RS04070	COG3468	outer membrane autotransporter barrel domain protein
ICI43_RS04080	COG4983	Phage plasmid primase, P4 family domain protein
ICI43_RS04115	COG4372	Transposase
ICI43_RS04125	COG3436	PFAM IS66 Orf2 family protein
ICI43_RS04140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ICI43_RS04145	COG1940	carbohydrate kinase activity
ICI43_RS04150	COG2814	Major facilitator Superfamily
ICI43_RS04160	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ICI43_RS04165	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ICI43_RS04170	COG2755	lipolytic protein G-D-S-L family
ICI43_RS04170	COG0657	acetylesterase activity
ICI43_RS04220	COG3468	outer membrane autotransporter barrel domain protein
ICI43_RS04235	COG3436	PFAM IS66 Orf2 family protein
ICI43_RS04255	COG4771	TonB-dependent receptor
ICI43_RS04390	COG3436	PFAM IS66 Orf2 family protein
ICI43_RS04410	COG2274	protein secretion by the type I secretion system
ICI43_RS04430	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ICI43_RS04440	COG0745	RESPONSE REGULATOR receiver
ICI43_RS04445	COG5002	protein histidine kinase activity
ICI43_RS04460	COG3436	PFAM IS66 Orf2 family protein
ICI43_RS04480	COG0582	viral genome integration into host DNA
ICI43_RS04490	COG1811	Na channel or pump
ICI43_RS04495	COG1982	Orn Lys Arg decarboxylase major
ICI43_RS04500	COG2211	Major facilitator Superfamily
ICI43_RS04510	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ICI43_RS04515	COG1194	a g-specific adenine glycosylase
ICI43_RS04525	COG3171	Protein conserved in bacteria
ICI43_RS04535	COG0252	asparaginase activity
ICI43_RS04545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ICI43_RS04550	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ICI43_RS04560	COG0762	integral membrane protein
ICI43_RS04565	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ICI43_RS04570	COG2805	Type II/IV secretion system protein
ICI43_RS04585	COG0189	ligase activity
ICI43_RS04590	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ICI43_RS04595	COG2356	endonuclease I
ICI43_RS04605	COG2814	Major facilitator Superfamily
ICI43_RS04625	COG1166	arginine decarboxylase activity
ICI43_RS04640	COG0501	Belongs to the peptidase M48B family
ICI43_RS04645	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ICI43_RS04650	COG0330	HflC and HflK could
ICI43_RS04655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICI43_RS04660	COG2213	PTS system mannitol-specific
ICI43_RS04665	COG1063	alcohol dehydrogenase
ICI43_RS04680	COG1072	(Pantothenic acid kinase))
ICI43_RS04685	COG1122	ATPase activity
ICI43_RS04720	COG0191	fructose-bisphosphate aldolase activity
ICI43_RS04725	COG0668	transmembrane transport
ICI43_RS04730	COG1279	arginine transmembrane transporter activity
ICI43_RS04735	COG2968	Membrane
ICI43_RS04740	COG0583	DNA-binding transcription factor activity
ICI43_RS04745	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ICI43_RS04745	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ICI43_RS04765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ICI43_RS04775	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ICI43_RS04795	COG0006	proline dipeptidase activity
ICI43_RS04800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ICI43_RS04805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ICI43_RS04815	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ICI43_RS04825	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ICI43_RS04825	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ICI43_RS04830	COG2723	6-phospho-beta-galactosidase activity
ICI43_RS04840	COG1272	protein, Hemolysin III
ICI43_RS04845	COG0354	folic acid binding
ICI43_RS04850	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ICI43_RS04860	COG0716	FMN binding
ICI43_RS04865	COG4974	Belongs to the 'phage' integrase family
ICI43_RS04870	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ICI43_RS04875	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ICI43_RS04885	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ICI43_RS04890	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ICI43_RS04905	COG2233	PERMEase
ICI43_RS04910	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ICI43_RS04910	COG0493	'glutamate synthase
ICI43_RS04915	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ICI43_RS04920	COG2252	PERMEase
ICI43_RS04925	COG0402	S-adenosylhomocysteine deaminase activity
ICI43_RS04930	COG2233	PERMEase
ICI43_RS04935	COG2080	2 iron, 2 sulfur cluster binding
ICI43_RS04935	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ICI43_RS04940	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ICI43_RS04945	COG0402	S-adenosylhomocysteine deaminase activity
ICI43_RS04950	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ICI43_RS04950	COG0493	'glutamate synthase
ICI43_RS04955	COG2068	MobA-Related Protein
ICI43_RS04960	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ICI43_RS04965	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ICI43_RS04965	COG3608	succinylglutamate desuccinylase aspartoacylase
ICI43_RS04970	COG0549	Belongs to the carbamate kinase family
ICI43_RS04980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ICI43_RS04985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ICI43_RS04990	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ICI43_RS04995	COG3829	transcription factor binding
ICI43_RS05000	COG2080	2 iron, 2 sulfur cluster binding
ICI43_RS05005	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ICI43_RS05010	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ICI43_RS05015	COG4942	peptidase
ICI43_RS05025	COG0814	amino acid
ICI43_RS05030	COG0183	Belongs to the thiolase family
ICI43_RS05040	COG1028	Short-chain dehydrogenase reductase Sdr
ICI43_RS05045	COG2814	Major facilitator Superfamily
ICI43_RS05050	COG1794	racemase activity, acting on amino acids and derivatives
ICI43_RS05055	COG0583	DNA-binding transcription factor activity
ICI43_RS05065	COG1609	Transcriptional regulator
ICI43_RS05080	COG0667	Aldo Keto reductase
ICI43_RS05090	COG0861	Integral membrane protein TerC family
ICI43_RS05105	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
ICI43_RS05120	COG2165	general secretion pathway protein
ICI43_RS05125	COG4795	General secretion pathway protein
ICI43_RS05135	COG4967	type IV pilus modification protein PilV
ICI43_RS05140	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ICI43_RS05145	COG1025	Belongs to the peptidase M16 family
ICI43_RS05150	COG1074	ATP-dependent DNA helicase activity
ICI43_RS05155	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ICI43_RS05160	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ICI43_RS05160	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ICI43_RS05165	COG0860	N-Acetylmuramoyl-L-alanine amidase
ICI43_RS05170	COG3711	transcriptional antiterminator
ICI43_RS05175	COG1263	PTS System
ICI43_RS05175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ICI43_RS05180	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ICI43_RS05275	COG2885	chlorophyll binding
ICI43_RS05315	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ICI43_RS05320	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ICI43_RS05325	COG2166	iron-sulfur cluster assembly
ICI43_RS05330	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ICI43_RS05340	COG0583	DNA-binding transcription factor activity
ICI43_RS05345	COG2363	Small membrane protein
ICI43_RS05355	COG1349	DNA-binding transcription factor activity
ICI43_RS05365	COG1070	Carbohydrate kinase
ICI43_RS05370	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
ICI43_RS05375	COG0738	Major facilitator superfamily
ICI43_RS05380	COG0235	Class ii aldolase
ICI43_RS05385	COG1454	alcohol dehydrogenase
ICI43_RS05395	COG1760	l-serine dehydratase
ICI43_RS05400	COG0814	amino acid
ICI43_RS05405	COG1611	Belongs to the LOG family
ICI43_RS05420	COG3098	single-species biofilm formation
ICI43_RS05425	COG0564	pseudouridine synthase activity
ICI43_RS05430	COG0716	FMN binding
ICI43_RS05435	COG2271	Major facilitator Superfamily
ICI43_RS05440	COG4948	Mandelate Racemase Muconate Lactonizing
ICI43_RS05445	COG4948	Mandelate Racemase Muconate Lactonizing
ICI43_RS05450	COG3437	response regulator, receiver
ICI43_RS05450	COG2205	protein histidine kinase activity
ICI43_RS05450	COG4999	Histidine kinase
ICI43_RS05450	COG3850	Histidine kinase
ICI43_RS05460	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ICI43_RS05465	COG3956	TIGRFAM MazG family protein
ICI43_RS05480	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ICI43_RS05490	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ICI43_RS05500	COG0602	queuosine metabolic process
ICI43_RS05505	COG1070	Carbohydrate kinase
ICI43_RS05510	COG2223	nitrite transmembrane transporter activity
ICI43_RS05515	COG1028	Short-chain dehydrogenase reductase Sdr
ICI43_RS05520	COG0277	FAD linked oxidase domain protein
ICI43_RS05525	COG0477	Major facilitator Superfamily
ICI43_RS05530	COG2086	electron transfer activity
ICI43_RS05535	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ICI43_RS05540	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ICI43_RS05545	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ICI43_RS05550	COG0644	oxidoreductase
ICI43_RS05555	COG0720	synthase
ICI43_RS05560	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ICI43_RS05565	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ICI43_RS05580	COG2234	aminopeptidase activity
ICI43_RS05620	COG0585	pseudouridine synthase activity
ICI43_RS05635	COG1388	LysM domain
ICI43_RS05635	COG4942	peptidase
ICI43_RS05655	COG2610	gluconate transmembrane transporter activity
ICI43_RS05660	COG3622	Belongs to the hyi family
ICI43_RS05665	COG0235	Class ii aldolase
ICI43_RS05670	COG3395	kinase activity
ICI43_RS05675	COG2084	Dehydrogenase
ICI43_RS05680	COG1349	DNA-binding transcription factor activity
ICI43_RS05685	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ICI43_RS05690	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ICI43_RS05705	COG3604	Transcriptional regulator
ICI43_RS05710	COG0309	Hydrogenase expression formation protein (HypE)
ICI43_RS05715	COG0409	Hydrogenase expression formation protein
ICI43_RS05720	COG0298	carbon dioxide binding
ICI43_RS05725	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ICI43_RS05730	COG0375	protein maturation
ICI43_RS05740	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ICI43_RS05745	COG0651	ATP synthesis coupled electron transport
ICI43_RS05750	COG0650	Formate hydrogenlyase subunit 4
ICI43_RS05755	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ICI43_RS05755	COG3261	NADH dehydrogenase
ICI43_RS05760	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ICI43_RS05765	COG3260	NADH ubiquinone oxidoreductase 20
ICI43_RS05775	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ICI43_RS05785	COG4680	protein conserved in bacteria
ICI43_RS05790	COG5499	transcription regulator containing HTH domain
ICI43_RS05800	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ICI43_RS05805	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ICI43_RS05810	COG0446	pyridine nucleotide-disulphide oxidoreductase
ICI43_RS05820	COG3604	Transcriptional regulator
ICI43_RS05825	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ICI43_RS05825	COG0517	IMP dehydrogenase activity
ICI43_RS05830	COG1349	DNA-binding transcription factor activity
ICI43_RS05835	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICI43_RS05840	COG1028	Short-chain dehydrogenase reductase Sdr
ICI43_RS05850	COG3732	PTS system glucitol sorbitol-specific
ICI43_RS05855	COG3730	PTS system glucitol sorbitol-specific
ICI43_RS05860	COG2951	lytic endotransglycosylase activity
ICI43_RS05865	COG1546	Belongs to the CinA family
ICI43_RS05885	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ICI43_RS05920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ICI43_RS05925	COG1238	metal cluster binding
ICI43_RS05950	COG2814	Major facilitator Superfamily
ICI43_RS05955	COG1566	PFAM secretion protein HlyD family protein
ICI43_RS05960	COG1846	Transcriptional regulator
ICI43_RS05970	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ICI43_RS05975	COG2814	Major facilitator Superfamily
ICI43_RS05980	COG2113	Glycine betaine
ICI43_RS05985	COG4176	ABC-type proline glycine betaine transport system permease component
ICI43_RS05990	COG4175	Glycine betaine
ICI43_RS05995	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICI43_RS06000	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICI43_RS06010	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ICI43_RS06015	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ICI43_RS06020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ICI43_RS06025	COG4575	ribosome binding
ICI43_RS06040	COG2916	Histone family protein nucleoid-structuring protein H-NS
ICI43_RS06045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ICI43_RS06050	COG0640	Transcriptional regulator
ICI43_RS06055	COG0401	homolog of Blt101
ICI43_RS06060	COG1652	LysM domain
ICI43_RS06065	COG1802	Transcriptional regulator
ICI43_RS06070	COG1113	amino acid transport
ICI43_RS06075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ICI43_RS06080	COG1012	belongs to the aldehyde dehydrogenase family
ICI43_RS06085	COG0579	oxidoreductase
ICI43_RS06105	COG2867	negative regulation of translational initiation
ICI43_RS06115	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ICI43_RS06120	COG0497	DNA recombination
ICI43_RS06135	COG4536	flavin adenine dinucleotide binding
ICI43_RS06140	COG4137	Cytochrome C assembly protein
ICI43_RS06145	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ICI43_RS06170	COG2885	chlorophyll binding
ICI43_RS06175	COG2199	diguanylate cyclase activity
ICI43_RS06190	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ICI43_RS06195	COG1605	Chorismate mutase
ICI43_RS06195	COG0287	Prephenate dehydrogenase
ICI43_RS06200	COG1605	Chorismate mutase
ICI43_RS06200	COG0077	Prephenate dehydratase
ICI43_RS06210	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ICI43_RS06215	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ICI43_RS06220	COG0564	pseudouridine synthase activity
ICI43_RS06230	COG0542	response to heat
ICI43_RS06255	COG0477	Major facilitator Superfamily
ICI43_RS06260	COG5544	Lipoprotein
ICI43_RS06265	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICI43_RS06270	COG0045	succinate-CoA ligase (ADP-forming) activity
ICI43_RS06270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ICI43_RS06270	COG1042	CoA-binding domain protein
ICI43_RS06275	COG3148	PFAM DTW domain containing protein
ICI43_RS06280	COG3118	belongs to the thioredoxin family
ICI43_RS06285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICI43_RS06305	COG0583	DNA-binding transcription factor activity
ICI43_RS06310	COG0513	Belongs to the DEAD box helicase family
ICI43_RS06320	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ICI43_RS06330	COG1595	DNA-templated transcription, initiation
ICI43_RS06335	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
ICI43_RS06340	COG3026	antisigma factor binding
ICI43_RS06345	COG3086	response to oxidative stress
ICI43_RS06355	COG0681	Belongs to the peptidase S26 family
ICI43_RS06375	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ICI43_RS06390	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ICI43_RS06395	COG1737	Transcriptional regulator
ICI43_RS06400	COG0560	Phosphoserine phosphatase
ICI43_RS06405	COG0590	tRNA wobble adenosine to inosine editing
ICI43_RS06410	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ICI43_RS06415	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICI43_RS06415	COG0047	phosphoribosylformylglycinamidine synthase activity
ICI43_RS06420	COG2205	protein histidine kinase activity
ICI43_RS06425	COG3170	Tfp pilus assembly protein FimV
ICI43_RS06430	COG2204	response regulator
ICI43_RS06435	COG0347	Belongs to the P(II) protein family
ICI43_RS06440	COG1017	nitric oxide dioxygenase activity
ICI43_RS06440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ICI43_RS06450	COG1940	carbohydrate kinase activity
ICI43_RS06455	COG0457	Tetratricopeptide repeat
ICI43_RS06460	COG1879	ABC-type sugar transport system periplasmic component
ICI43_RS06465	COG1129	ABC transporter
ICI43_RS06470	COG1172	Belongs to the binding-protein-dependent transport system permease family
ICI43_RS06475	COG1063	alcohol dehydrogenase
ICI43_RS06480	COG2017	converts alpha-aldose to the beta-anomer
ICI43_RS06485	COG2259	Doxx family
ICI43_RS06490	COG2814	Major facilitator Superfamily
ICI43_RS06495	COG3711	transcriptional antiterminator
ICI43_RS06500	COG1073	alpha beta
ICI43_RS06505	COG0483	inositol monophosphate 1-phosphatase activity
ICI43_RS06525	COG0822	iron-sulfur transferase activity
ICI43_RS06545	COG0633	Ferredoxin
ICI43_RS06550	COG2975	iron-sulfur cluster assembly
ICI43_RS06565	COG2897	thiosulfate sulfurtransferase activity
ICI43_RS06570	COG2373	Large extracellular alpha-helical protein
ICI43_RS06575	COG4953	penicillin-binding protein 1C
ICI43_RS06585	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ICI43_RS06605	COG2976	Protein conserved in bacteria
ICI43_RS06620	COG1645	bacterial-type flagellum-dependent swarming motility
ICI43_RS06640	COG1570	exodeoxyribonuclease VII activity
ICI43_RS06645	COG0516	GMP reductase activity
ICI43_RS06645	COG0517	IMP dehydrogenase activity
ICI43_RS06660	COG3133	Outer membrane lipoprotein
ICI43_RS06675	COG2200	EAL domain
ICI43_RS06680	COG0248	Ppx GppA phosphatase
ICI43_RS06685	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ICI43_RS06690	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ICI43_RS06705	COG2233	PERMEase
ICI43_RS06715	COG1393	Belongs to the ArsC family
ICI43_RS06720	COG4783	chaperone-mediated protein folding
ICI43_RS06725	COG0628	permease
ICI43_RS06730	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ICI43_RS06735	COG2716	regulation of RNA biosynthetic process
ICI43_RS06745	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ICI43_RS06755	COG2321	neutral zinc metallopeptidase
ICI43_RS06765	COG0400	carboxylic ester hydrolase activity
ICI43_RS06780	COG1393	Belongs to the ArsC family
ICI43_RS06790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICI43_RS06795	COG3850	Histidine kinase
ICI43_RS06800	COG0493	'glutamate synthase
ICI43_RS06800	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ICI43_RS06810	COG5342	invasion associated locus B
ICI43_RS06815	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ICI43_RS06820	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ICI43_RS06825	COG0281	malic enzyme
ICI43_RS06825	COG0280	phosphate acetyltransferase
ICI43_RS06830	COG4810	utilization protein
ICI43_RS06835	COG4917	ethanolamine utilization protein
ICI43_RS06840	COG4766	ethanolamine catabolic process
ICI43_RS06845	COG4812	Cobalamin adenosyltransferase
ICI43_RS06850	COG0280	phosphate acetyltransferase
ICI43_RS06855	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ICI43_RS06860	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
ICI43_RS06865	COG1012	belongs to the aldehyde dehydrogenase family
ICI43_RS06870	COG4820	ethanolamine utilization protein (EutJ)
ICI43_RS06875	COG1454	alcohol dehydrogenase
ICI43_RS06880	COG3192	ethanolamine utilization protein
ICI43_RS06885	COG4819	ethanolamine utilization protein
ICI43_RS06890	COG4303	Ethanolamine ammonia lyase large subunit
ICI43_RS06900	COG4816	utilization protein
ICI43_RS06905	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ICI43_RS06910	COG2207	Transcriptional regulator
ICI43_RS06920	COG0860	N-Acetylmuramoyl-L-alanine amidase
ICI43_RS06940	COG2837	iron assimilation
ICI43_RS06945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ICI43_RS06945	COG1263	PTS System
ICI43_RS06955	COG1028	Short-chain dehydrogenase reductase Sdr
ICI43_RS06960	COG4150	thiosulfate binding
ICI43_RS06965	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ICI43_RS06970	COG4208	sulfate ABC transporter
ICI43_RS06975	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ICI43_RS06980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ICI43_RS06995	COG2190	(PTS) system
ICI43_RS07000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ICI43_RS07005	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICI43_RS07010	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ICI43_RS07020	COG3115	cell septum assembly
ICI43_RS07030	COG3530	Putative quorum-sensing-regulated virulence factor
ICI43_RS07035	COG0385	Bile acid
ICI43_RS07040	COG0583	DNA-binding transcription factor activity
ICI43_RS07050	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ICI43_RS07055	COG2211	Major facilitator Superfamily
ICI43_RS07065	COG0583	DNA-binding transcription factor activity
ICI43_RS07090	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ICI43_RS07095	COG3415	Transposase
ICI43_RS07100	COG3415	Transposase
ICI43_RS07115	COG2200	EAL domain
ICI43_RS07115	COG2199	diguanylate cyclase activity
ICI43_RS07120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ICI43_RS07135	COG0038	chloride channel
ICI43_RS07145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ICI43_RS07150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ICI43_RS07155	COG0006	proline dipeptidase activity
ICI43_RS07160	COG1363	Peptidase, m42
ICI43_RS07165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICI43_RS07165	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ICI43_RS07165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICI43_RS07170	COG2207	Transcriptional regulator
ICI43_RS07175	COG3279	Response regulator of the LytR AlgR family
ICI43_RS07180	COG3275	phosphorelay sensor kinase activity
ICI43_RS07185	COG0436	Aminotransferase
ICI43_RS07195	COG1560	Kdo2-lipid A biosynthetic process
ICI43_RS07215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ICI43_RS07220	COG0028	Belongs to the TPP enzyme family
ICI43_RS07225	COG0679	Auxin Efflux Carrier
ICI43_RS07230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ICI43_RS07235	COG2205	protein histidine kinase activity
ICI43_RS07235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICI43_RS07235	COG0784	Response regulator, receiver
ICI43_RS07235	COG2198	Histidine kinase
ICI43_RS07240	COG2197	response regulator
ICI43_RS07245	COG1566	PFAM secretion protein HlyD family protein
ICI43_RS07250	COG0477	Major facilitator Superfamily
ICI43_RS07255	COG3048	D-serine ammonia-lyase activity
ICI43_RS07260	COG2610	gluconate transmembrane transporter activity
ICI43_RS07265	COG0583	DNA-binding transcription factor activity
ICI43_RS07270	COG0582	viral genome integration into host DNA
ICI43_RS07275	COG0582	viral genome integration into host DNA
ICI43_RS07300	COG2116	formate transmembrane transporter activity
ICI43_RS07310	COG2067	long-chain fatty acid transport protein
ICI43_RS07315	COG3691	Protein conserved in bacteria
ICI43_RS07320	COG0183	Belongs to the thiolase family
ICI43_RS07325	COG1024	Enoyl-CoA hydratase
ICI43_RS07325	COG1250	3-hydroxyacyl-CoA dehydrogenase
ICI43_RS07330	COG2062	phosphohistidine phosphatase, SixA
ICI43_RS07335	COG3539	Fimbrial protein
ICI43_RS07340	COG3188	usher protein
ICI43_RS07345	COG3121	Chaperone
ICI43_RS07350	COG3539	Fimbrial protein
ICI43_RS07355	COG3539	Fimbrial protein
ICI43_RS07360	COG3539	Fimbrial protein
ICI43_RS07390	COG0730	response to heat
ICI43_RS07395	COG3101	peptidyl-lysine hydroxylation
ICI43_RS07405	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ICI43_RS07405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ICI43_RS07410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ICI43_RS07415	COG2814	Major facilitator Superfamily
ICI43_RS07430	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ICI43_RS07440	COG0586	Pfam SNARE associated Golgi protein
ICI43_RS07450	COG0285	dihydrofolate synthase activity
ICI43_RS07455	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ICI43_RS07460	COG1286	toxin biosynthetic process
ICI43_RS07465	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ICI43_RS07470	COG0163	prenyltransferase activity
ICI43_RS07480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICI43_RS07485	COG4215	(ABC) transporter
ICI43_RS07490	COG4160	amino acid transport
ICI43_RS07495	COG4598	ABC transporter
ICI43_RS07500	COG1090	epimerase
ICI43_RS07505	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ICI43_RS07510	COG0625	glutathione transferase activity
ICI43_RS07515	COG0625	glutathione transferase activity
ICI43_RS07520	COG0622	Phosphoesterase
ICI43_RS07525	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ICI43_RS07530	COG1288	antiporter activity
ICI43_RS07535	COG0280	phosphate acetyltransferase
ICI43_RS07535	COG0857	belongs to the CobB CobQ family
ICI43_RS07540	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ICI43_RS07545	COG3092	negative regulation of chromosome organization
ICI43_RS07555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ICI43_RS07560	COG0490	domain, Protein
ICI43_RS07560	COG0471	metal ion transport
ICI43_RS07570	COG0436	Aminotransferase
ICI43_RS07575	COG0583	DNA-binding transcription factor activity
ICI43_RS07595	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ICI43_RS07600	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ICI43_RS07605	COG1034	ATP synthesis coupled electron transport
ICI43_RS07620	COG0839	Belongs to the complex I subunit 6 family
ICI43_RS07630	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ICI43_RS07635	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ICI43_RS07650	COG2234	aminopeptidase activity
ICI43_RS07655	COG2304	oxidoreductase activity
ICI43_RS07665	COG2153	protein acetylation
ICI43_RS07670	COG4575	ribosome binding
ICI43_RS07675	COG1169	isochorismate synthase
ICI43_RS07690	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ICI43_RS07695	COG1441	menaquinone biosynthetic process
ICI43_RS07700	COG0318	PFAM AMP-dependent synthetase and ligase
ICI43_RS07720	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ICI43_RS07730	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ICI43_RS07730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ICI43_RS07765	COG1414	Transcriptional regulator
ICI43_RS07770	COG4948	Mandelate Racemase Muconate Lactonizing
ICI43_RS07775	COG2271	Major facilitator Superfamily
ICI43_RS07785	COG5464	transposase or invertase
ICI43_RS07790	COG0247	lactate metabolic process
ICI43_RS07795	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
ICI43_RS07800	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ICI43_RS07805	COG2271	Major facilitator Superfamily
ICI43_RS07810	COG0584	glycerophosphoryl diester phosphodiesterase
ICI43_RS07815	COG3642	lipopolysaccharide core region biosynthetic process
ICI43_RS07820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ICI43_RS07825	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICI43_RS07830	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICI43_RS07835	COG3468	outer membrane autotransporter barrel domain protein
ICI43_RS07840	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ICI43_RS07845	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ICI43_RS07850	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
ICI43_RS07855	COG3234	Protein of unknown function (DUF1175)
ICI43_RS07860	COG2373	Large extracellular alpha-helical protein
ICI43_RS07865	COG5445	Predicted secreted protein (DUF2300)
ICI43_RS07870	COG4676	Protein conserved in bacteria
ICI43_RS07875	COG0183	Belongs to the thiolase family
ICI43_RS07880	COG2031	fatty acid transporter
ICI43_RS07885	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ICI43_RS07890	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ICI43_RS07895	COG2204	response regulator
ICI43_RS07900	COG3852	Histidine kinase
ICI43_RS07905	COG2205	protein histidine kinase activity
ICI43_RS07905	COG0784	Response regulator, receiver
ICI43_RS07910	COG2197	response regulator
ICI43_RS07915	COG2198	Histidine kinase
ICI43_RS07915	COG0642	Histidine kinase
ICI43_RS07920	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ICI43_RS07925	COG1477	protein flavinylation
ICI43_RS07930	COG2169	Transcriptional regulator
ICI43_RS07930	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ICI43_RS07935	COG3145	DNA-N1-methyladenine dioxygenase activity
ICI43_RS07940	COG4615	Cyclic peptide transporter
ICI43_RS07945	COG0579	oxidoreductase
ICI43_RS07955	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
ICI43_RS07955	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ICI43_RS07960	COG3062	negative regulation of establishment of protein localization
ICI43_RS07970	COG0437	4 iron, 4 sulfur cluster binding
ICI43_RS07975	COG0348	domain, Protein
ICI43_RS07980	COG3043	anaerobic respiration
ICI43_RS07985	COG3005	denitrification pathway
ICI43_RS07990	COG4133	protoheme IX ABC transporter activity
ICI43_RS07995	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ICI43_RS08000	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ICI43_RS08005	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ICI43_RS08015	COG1138	Cytochrome C-type biogenesis protein
ICI43_RS08020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ICI43_RS08025	COG4235	cytochrome complex assembly
ICI43_RS08025	COG3088	subunit of a heme lyase
ICI43_RS08030	COG2197	response regulator
ICI43_RS08045	COG4220	transposase activity
ICI43_RS08120	COG0582	viral genome integration into host DNA
ICI43_RS08130	COG3083	sulfuric ester hydrolase activity
ICI43_RS08150	COG1061	Type III restriction enzyme res subunit
ICI43_RS08155	COG1187	pseudouridine synthase activity
ICI43_RS08160	COG2814	Major facilitator Superfamily
ICI43_RS08170	COG4172	Belongs to the ABC transporter superfamily
ICI43_RS08175	COG4239	(ABC) transporter, permease
ICI43_RS08180	COG4174	ABC transporter (Permease)
ICI43_RS08185	COG4166	transmembrane transport
ICI43_RS08190	COG2200	EAL domain
ICI43_RS08195	COG0791	NLP P60 protein
ICI43_RS08200	COG0671	phosphoesterase, PA-phosphatase related
ICI43_RS08205	COG0523	cobalamin synthesis protein
ICI43_RS08210	COG0246	Mannitol dehydrogenase
ICI43_RS08225	COG2814	Major facilitator Superfamily
ICI43_RS08230	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICI43_RS08230	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICI43_RS08235	COG1105	Belongs to the carbohydrate kinase PfkB family
ICI43_RS08240	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ICI43_RS08240	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ICI43_RS08240	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ICI43_RS08245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICI43_RS08250	COG2313	pseudouridylate synthase activity
ICI43_RS08255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ICI43_RS08260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ICI43_RS08270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICI43_RS08270	COG1522	sequence-specific DNA binding
ICI43_RS08280	COG2855	membrane
ICI43_RS08285	COG0583	DNA-binding transcription factor activity
ICI43_RS08290	COG0833	amino acid
ICI43_RS08295	COG4771	TonB-dependent receptor
ICI43_RS08310	COG2311	Membrane
ICI43_RS08315	COG1609	Transcriptional regulator
ICI43_RS08320	COG1879	ABC-type sugar transport system periplasmic component
ICI43_RS08330	COG4211	Belongs to the binding-protein-dependent transport system permease family
ICI43_RS08335	COG0167	dihydroorotate dehydrogenase activity
ICI43_RS08335	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ICI43_RS08340	COG0493	'glutamate synthase
ICI43_RS08350	COG2949	membrane
ICI43_RS08360	COG1346	cytolysis
ICI43_RS08370	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICI43_RS08380	COG1538	Outer membrane efflux protein
ICI43_RS08390	COG0586	Pfam SNARE associated Golgi protein
ICI43_RS08400	COG1686	Belongs to the peptidase S11 family
ICI43_RS08405	COG0277	FAD linked oxidase domain protein
ICI43_RS08410	COG1472	Belongs to the glycosyl hydrolase 3 family
ICI43_RS08415	COG1732	Glycine betaine
ICI43_RS08420	COG1174	glycine betaine transport
ICI43_RS08425	COG1125	glycine betaine transport
ICI43_RS08430	COG1174	glycine betaine transport
ICI43_RS08440	COG0789	Transcriptional regulator
ICI43_RS08445	COG3275	phosphorelay sensor kinase activity
ICI43_RS08450	COG3279	Response regulator of the LytR AlgR family
ICI43_RS08455	COG4807	Protein conserved in bacteria
ICI43_RS08460	COG4808	Protein conserved in bacteria
ICI43_RS08465	COG4715	Zinc finger, swim domain protein
ICI43_RS08470	COG3552	Protein containing von Willebrand factor type A (VWA) domain
ICI43_RS08475	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ICI43_RS08480	COG0714	Associated with various cellular activities
ICI43_RS08490	COG3831	ATPase activity
ICI43_RS08495	COG3831	ATPase activity
ICI43_RS08505	COG0489	protein tyrosine kinase activity
ICI43_RS08515	COG3539	Fimbrial protein
ICI43_RS08520	COG3121	Chaperone
ICI43_RS08525	COG3188	usher protein
ICI43_RS08530	COG3539	Fimbrial protein
ICI43_RS08535	COG5455	response to cobalt ion
ICI43_RS08550	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ICI43_RS08555	COG0351	phosphomethylpyrimidine kinase
ICI43_RS08560	COG3757	hydrolase, family 25
ICI43_RS08565	COG2188	Transcriptional regulator
ICI43_RS08570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICI43_RS08575	COG1397	ADP-ribosylglycohydrolase
ICI43_RS08580	COG2211	Major facilitator Superfamily
ICI43_RS08585	COG1830	Aldolase
ICI43_RS08590	COG0191	fructose-bisphosphate aldolase activity
ICI43_RS08600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICI43_RS08605	COG3414	Phosphotransferase system galactitol-specific IIB component
ICI43_RS08610	COG3775	system Galactitol-specific IIC component
ICI43_RS08615	COG1063	alcohol dehydrogenase
ICI43_RS08625	COG1597	lipid kinase activity
ICI43_RS08635	COG0826	peptidase U32
ICI43_RS08660	COG3422	double-strand break repair
ICI43_RS08665	COG0745	RESPONSE REGULATOR receiver
ICI43_RS08670	COG2205	protein histidine kinase activity
ICI43_RS08675	COG2814	Major facilitator Superfamily
ICI43_RS08680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICI43_RS08690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICI43_RS08705	COG4245	von Willebrand factor, type A
ICI43_RS08710	COG0631	protein serine/threonine phosphatase activity
ICI43_RS08715	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
ICI43_RS08720	COG0443	Heat shock 70 kDa protein
ICI43_RS08725	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ICI43_RS08730	COG3447	MASE1 domain protein
ICI43_RS08730	COG5001	Diguanylate cyclase
ICI43_RS08730	COG5002	protein histidine kinase activity
ICI43_RS08735	COG0572	uridine kinase
ICI43_RS08745	COG2982	Protein involved in outer membrane biogenesis
ICI43_RS08750	COG1253	flavin adenine dinucleotide binding
ICI43_RS08760	COG1596	polysaccharide export
ICI43_RS08765	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ICI43_RS08770	COG3206	protein involved in exopolysaccharide biosynthesis
ICI43_RS08770	COG0489	protein tyrosine kinase activity
ICI43_RS08775	COG0463	Glycosyl transferase, family 2
ICI43_RS08780	COG1045	serine acetyltransferase
ICI43_RS08785	COG0438	transferase activity, transferring glycosyl groups
ICI43_RS08795	COG1216	Glycosyl transferase, family 2
ICI43_RS08800	COG0110	maltose O-acetyltransferase activity
ICI43_RS08805	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ICI43_RS08810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ICI43_RS08815	COG1051	belongs to the nudix hydrolase family
ICI43_RS08820	COG0297	glycogen (starch) synthase activity
ICI43_RS08825	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ICI43_RS08825	COG0662	Cupin 2, conserved barrel domain protein
ICI43_RS08830	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ICI43_RS08835	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ICI43_RS08840	COG2244	polysaccharide biosynthetic process
ICI43_RS08845	COG2327	Polysaccharide pyruvyl transferase
ICI43_RS08850	COG0438	transferase activity, transferring glycosyl groups
ICI43_RS08860	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ICI43_RS08875	COG1216	Glycosyl transferase, family 2
ICI43_RS08890	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ICI43_RS08905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ICI43_RS08910	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ICI43_RS08915	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ICI43_RS08920	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ICI43_RS08925	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ICI43_RS08925	COG0140	phosphoribosyl-ATP diphosphatase activity
ICI43_RS08940	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ICI43_RS08945	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ICI43_RS08945	COG0131	Imidazoleglycerol-phosphate dehydratase
ICI43_RS08955	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ICI43_RS08970	COG2161	toxin-antitoxin pair type II binding
ICI43_RS08975	COG4115	mRNA cleavage
ICI43_RS08980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ICI43_RS08985	COG0583	DNA-binding transcription factor activity
ICI43_RS08995	COG0531	amino acid
ICI43_RS09000	COG2925	Exonuclease
ICI43_RS09005	COG1686	Belongs to the peptidase S11 family
ICI43_RS09025	COG1289	transmembrane transporter activity
ICI43_RS09040	COG4372	Transposase
ICI43_RS09070	COG2003	Belongs to the UPF0758 family
ICI43_RS09125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICI43_RS09130	COG1120	ATPase activity
ICI43_RS09185	COG3547	Transposase (IS116 IS110 IS902 family)
ICI43_RS09220	COG1735	metal-dependent hydrolase with the TIM-barrel fold
ICI43_RS09235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICI43_RS09255	COG1215	transferase activity, transferring glycosyl groups
ICI43_RS09260	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ICI43_RS09265	COG3969	phosphoadenosine phosphosulfate
ICI43_RS09270	COG1475	DNA binding
ICI43_RS09275	COG4771	TonB-dependent receptor
ICI43_RS09280	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
ICI43_RS09295	COG1376	ErfK ybiS ycfS ynhG family protein
ICI43_RS09315	COG2197	response regulator
ICI43_RS09330	COG1250	3-hydroxyacyl-CoA dehydrogenase
ICI43_RS09335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICI43_RS09340	COG1960	acyl-CoA dehydrogenase activity
ICI43_RS09370	COG0154	amidase activity
ICI43_RS09395	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ICI43_RS09405	COG0582	viral genome integration into host DNA
ICI43_RS09415	COG0534	Mate efflux family protein
ICI43_RS09425	COG0583	DNA-binding transcription factor activity
ICI43_RS09430	COG0583	DNA-binding transcription factor activity
ICI43_RS09440	COG0217	transcriptional regulatory protein
ICI43_RS09445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ICI43_RS09450	COG0477	Major facilitator Superfamily
ICI43_RS09465	COG4932	domain protein
ICI43_RS09465	COG1388	LysM domain
ICI43_RS09465	COG2373	Large extracellular alpha-helical protein
ICI43_RS09470	COG4771	TonB-dependent receptor
ICI43_RS09475	COG1021	2,3-dihydroxybenzoate-AMP ligase
ICI43_RS09495	COG3433	isochorismatase activity
ICI43_RS09495	COG2226	methyltransferase
ICI43_RS09495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ICI43_RS09510	COG1132	(ABC) transporter
ICI43_RS09515	COG2814	Major facilitator Superfamily
ICI43_RS09525	COG0582	viral genome integration into host DNA
ICI43_RS09635	COG4916	TIR domain
ICI43_RS09665	COG0582	viral genome integration into host DNA
ICI43_RS09670	COG3443	Belongs to the bacterial solute-binding protein 9 family
ICI43_RS09675	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ICI43_RS09680	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ICI43_RS09685	COG2351	hydroxyisourate hydrolase activity
ICI43_RS09690	COG0745	RESPONSE REGULATOR receiver
ICI43_RS09695	COG2205	protein histidine kinase activity
ICI43_RS09705	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ICI43_RS09715	COG1418	mRNA catabolic process
ICI43_RS09720	COG0270	DNA (cytosine-5-)-methyltransferase activity
ICI43_RS09725	COG3727	T/G mismatch-specific endonuclease activity
ICI43_RS09730	COG0697	spore germination
ICI43_RS09735	COG2354	Protein conserved in bacteria
ICI43_RS09740	COG5475	Uncharacterized small protein (DUF2158)
ICI43_RS09745	COG3706	GGDEF domain
ICI43_RS09750	COG3769	mannosylglycerate metabolic process
ICI43_RS09765	COG2197	response regulator
ICI43_RS09770	COG1684	flagellar biosynthetic protein fliR
ICI43_RS09775	COG1987	bacterial-type flagellum assembly
ICI43_RS09780	COG1338	Plays a role in the flagellum-specific transport system
ICI43_RS09785	COG3190	flagellar
ICI43_RS09790	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ICI43_RS09795	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ICI43_RS09800	COG1580	Controls the rotational direction of flagella during chemotaxis
ICI43_RS09805	COG3144	bacterial-type flagellum assembly
ICI43_RS09810	COG2882	bacterial-type flagellum organization
ICI43_RS09815	COG1157	protein secretion by the type III secretion system
ICI43_RS09820	COG1317	bacterial-type flagellum organization
ICI43_RS09825	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ICI43_RS09830	COG1766	The M ring may be actively involved in energy transduction
ICI43_RS09840	COG2076	Multidrug Resistance protein
ICI43_RS09845	COG1881	PFAM PEBP family protein
ICI43_RS09850	COG2207	Transcriptional regulator
ICI43_RS09865	COG2135	peptidase activity
ICI43_RS09870	COG0425	Belongs to the sulfur carrier protein TusA family
ICI43_RS09875	COG2391	methyltransferase activity
ICI43_RS09885	COG0366	Alpha amylase catalytic
ICI43_RS09895	COG1516	flagellar protein fliS
ICI43_RS09900	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ICI43_RS09910	COG1191	sigma factor activity
ICI43_RS09920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICI43_RS09925	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ICI43_RS09930	COG0765	amino acid transport
ICI43_RS09935	COG1126	abc transporter atp-binding protein
ICI43_RS09940	COG2197	response regulator
ICI43_RS09955	COG2197	response regulator
ICI43_RS09985	COG3012	SEC-C Motif Domain Protein
ICI43_RS09985	COG3318	Belongs to the UPF0149 family
ICI43_RS09990	COG0814	amino acid
ICI43_RS10000	COG1528	Iron-storage protein
ICI43_RS10020	COG1528	Iron-storage protein
ICI43_RS10025	COG1879	ABC-type sugar transport system periplasmic component
ICI43_RS10030	COG1129	ABC transporter
ICI43_RS10035	COG1172	Belongs to the binding-protein-dependent transport system permease family
ICI43_RS10040	COG1877	trehalose-phosphatase activity
ICI43_RS10050	COG0589	response to stress
ICI43_RS10065	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ICI43_RS10070	COG1360	Flagellar Motor Protein
ICI43_RS10075	COG2198	Histidine kinase
ICI43_RS10075	COG0643	Histidine kinase
ICI43_RS10080	COG0835	chemotaxis
ICI43_RS10085	COG0840	transmembrane signaling receptor activity
ICI43_RS10095	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ICI43_RS10105	COG0745	RESPONSE REGULATOR receiver
ICI43_RS10110	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ICI43_RS10115	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ICI43_RS10120	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ICI43_RS10135	COG3102	Protein conserved in bacteria
ICI43_RS10145	COG3005	denitrification pathway
ICI43_RS10150	COG0243	molybdopterin cofactor binding
ICI43_RS10165	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ICI43_RS10170	COG1801	Protein of unknown function DUF72
ICI43_RS10175	COG1335	isochorismatase
ICI43_RS10185	COG0494	nUDIX hydrolase
ICI43_RS10190	COG0217	transcriptional regulatory protein
ICI43_RS10220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ICI43_RS10230	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ICI43_RS10235	COG0739	heme binding
ICI43_RS10240	COG1560	Kdo2-lipid A biosynthetic process
ICI43_RS10245	COG0469	pyruvate kinase activity
ICI43_RS10250	COG1737	Transcriptional regulator
ICI43_RS10255	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ICI43_RS10260	COG0129	dihydroxy-acid dehydratase activity
ICI43_RS10265	COG0800	Aldolase
ICI43_RS10275	COG3141	response to X-ray
ICI43_RS10285	COG2979	Protein of unknown function (DUF533)
ICI43_RS10295	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ICI43_RS10300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ICI43_RS10310	COG2372	response to copper ion
ICI43_RS10315	COG1276	copper resistance
ICI43_RS10325	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ICI43_RS10340	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ICI43_RS10340	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ICI43_RS10345	COG3008	intermembrane lipid transfer
ICI43_RS10350	COG2995	paraquat-inducible protein a
ICI43_RS10355	COG1956	GAF domain-containing protein
ICI43_RS10365	COG0793	Belongs to the peptidase S41A family
ICI43_RS10375	COG2814	Major facilitator Superfamily
ICI43_RS10380	COG1414	Transcriptional regulator
ICI43_RS10410	COG2226	methyltransferase
ICI43_RS10425	COG3716	PTS system mannose fructose sorbose family IID component
ICI43_RS10430	COG3715	PTS system
ICI43_RS10435	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ICI43_RS10435	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICI43_RS10440	COG1253	flavin adenine dinucleotide binding
ICI43_RS10445	COG2200	EAL domain
ICI43_RS10450	COG1760	l-serine dehydratase
ICI43_RS10455	COG0494	nUDIX hydrolase
ICI43_RS10460	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ICI43_RS10475	COG0251	oxidation-reduction process
ICI43_RS10480	COG1199	ATP-dependent helicase activity
ICI43_RS10485	COG1214	PFAM Peptidase M22, glycoprotease
ICI43_RS10490	COG3065	identical protein binding
ICI43_RS10495	COG0318	PFAM AMP-dependent synthetase and ligase
ICI43_RS10500	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ICI43_RS10505	COG0583	DNA-binding transcription factor activity
ICI43_RS10515	COG3615	Tellurite resistance protein tehB
ICI43_RS10525	COG2261	transglycosylase associated protein
ICI43_RS10540	COG2199	diguanylate cyclase activity
ICI43_RS10540	COG2203	Gaf domain
ICI43_RS10545	COG3042	response to heat
ICI43_RS10550	COG3189	MarR family transcriptional regulator
ICI43_RS10555	COG2807	transmembrane transport
ICI43_RS10560	COG2207	Transcriptional regulator
ICI43_RS10575	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ICI43_RS10580	COG2199	diguanylate cyclase activity
ICI43_RS10585	COG2199	diguanylate cyclase activity
ICI43_RS10595	COG2766	serine protein kinase
ICI43_RS10600	COG3713	MltA-interacting MipA family protein
ICI43_RS10605	COG0656	L-ascorbic acid biosynthetic process
ICI43_RS10610	COG0676	glucose-6-phosphate 1-epimerase activity
ICI43_RS10615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ICI43_RS10625	COG3139	Protein of unknown function (DUF1315)
ICI43_RS10630	COG1063	alcohol dehydrogenase
ICI43_RS10635	COG2271	Major facilitator Superfamily
ICI43_RS10640	COG1063	alcohol dehydrogenase
ICI43_RS10645	COG0191	fructose-bisphosphate aldolase activity
ICI43_RS10650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICI43_RS10655	COG0667	Aldo Keto reductase
ICI43_RS10660	COG1349	DNA-binding transcription factor activity
ICI43_RS10665	COG2814	Major facilitator Superfamily
ICI43_RS10670	COG1335	isochorismatase
ICI43_RS10675	COG0252	asparaginase activity
ICI43_RS10680	COG0616	signal peptide processing
ICI43_RS10685	COG0778	Nitroreductase
ICI43_RS10690	COG0709	Synthesizes selenophosphate from selenide and ATP
ICI43_RS10695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ICI43_RS10705	COG0443	Heat shock 70 kDa protein
ICI43_RS10715	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ICI43_RS10725	COG0494	nUDIX hydrolase
ICI43_RS10730	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ICI43_RS10735	COG2897	thiosulfate sulfurtransferase activity
ICI43_RS10740	COG4136	ATPase activity
ICI43_RS10745	COG4135	transport system, permease component
ICI43_RS10750	COG4134	Bacterial extracellular solute-binding protein
ICI43_RS10755	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ICI43_RS10760	COG0398	Pfam SNARE associated Golgi protein
ICI43_RS10770	COG0398	Pfam SNARE associated Golgi protein
ICI43_RS10775	COG0708	Exodeoxyribonuclease III
ICI43_RS10790	COG1012	belongs to the aldehyde dehydrogenase family
ICI43_RS10795	COG3724	N-succinylarginine dihydrolase activity
ICI43_RS10805	COG3678	ATP-independent chaperone mediated protein folding
ICI43_RS10815	COG0322	excinuclease ABC activity
ICI43_RS10825	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ICI43_RS10830	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ICI43_RS10835	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ICI43_RS10840	COG1447	Phosphotransferase system cellobiose-specific component IIA
ICI43_RS10845	COG1917	Cupin 2, conserved barrel domain protein
ICI43_RS10845	COG2169	Transcriptional regulator
ICI43_RS10850	COG1486	melibiose metabolic process
ICI43_RS10855	COG3394	polysaccharide catabolic process
ICI43_RS10860	COG0753	catalase activity
ICI43_RS10870	COG1823	symporter activity
ICI43_RS10875	COG1988	membrane-bound metal-dependent
ICI43_RS10880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ICI43_RS10890	COG3001	Fructosamine kinase
ICI43_RS10900	COG1105	Belongs to the carbohydrate kinase PfkB family
ICI43_RS10905	COG3137	Salt-induced outer membrane protein
ICI43_RS10960	COG4139	cobalamin transport
ICI43_RS10965	COG0386	Belongs to the glutathione peroxidase family
ICI43_RS10975	COG0791	NLP P60 protein
ICI43_RS10980	COG2200	EAL domain
ICI43_RS10990	COG4256	Hemin uptake protein
ICI43_RS10995	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ICI43_RS11005	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ICI43_RS11005	COG0574	Belongs to the PEP-utilizing enzyme family
ICI43_RS11010	COG0318	PFAM AMP-dependent synthetase and ligase
ICI43_RS11015	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ICI43_RS11020	COG0644	oxidoreductase
ICI43_RS11025	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ICI43_RS11030	COG2086	electron transfer activity
ICI43_RS11035	COG1917	Cupin 2, conserved barrel domain protein
ICI43_RS11035	COG2207	Transcriptional regulator
ICI43_RS11040	COG1960	acyl-CoA dehydrogenase activity
ICI43_RS11045	COG4670	ketone body catabolic process
ICI43_RS11060	COG2271	Major facilitator Superfamily
ICI43_RS11065	COG0738	Major facilitator superfamily
ICI43_RS11080	COG0628	permease
ICI43_RS11085	COG0277	FAD linked oxidase domain protein
ICI43_RS11085	COG0247	lactate metabolic process
ICI43_RS11090	COG2050	protein possibly involved in aromatic compounds catabolism
ICI43_RS11100	COG0316	Belongs to the HesB IscA family
ICI43_RS11105	COG0719	Fe-S assembly protein
ICI43_RS11110	COG0396	ATPase activity
ICI43_RS11115	COG0719	Fe-S assembly protein
ICI43_RS11130	COG1376	ErfK ybiS ycfS ynhG family protein
ICI43_RS11135	COG4238	major outer membrane lipoprotein
ICI43_RS11140	COG0469	pyruvate kinase activity
ICI43_RS11150	COG0437	4 iron, 4 sulfur cluster binding
ICI43_RS11155	COG2414	aldehyde ferredoxin oxidoreductase
ICI43_RS11165	COG0437	4 iron, 4 sulfur cluster binding
ICI43_RS11170	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
ICI43_RS11180	COG4529	Protein conserved in bacteria
ICI43_RS11200	COG3468	outer membrane autotransporter barrel domain protein
ICI43_RS11210	COG0307	riboflavin synthase, alpha
ICI43_RS11215	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ICI43_RS11220	COG2814	Major facilitator Superfamily
ICI43_RS11225	COG0583	DNA-binding transcription factor activity
ICI43_RS11230	COG1609	Transcriptional regulator
ICI43_RS11240	COG2814	Major facilitator Superfamily
ICI43_RS11245	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ICI43_RS11250	COG0791	NLP P60 protein
ICI43_RS11255	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ICI43_RS11260	COG1201	RNA secondary structure unwinding
ICI43_RS11265	COG1201	RNA secondary structure unwinding
ICI43_RS11275	COG0346	lactoylglutathione lyase activity
ICI43_RS11280	COG1902	pentaerythritol trinitrate reductase activity
ICI43_RS11285	COG1309	transcriptional regulator
ICI43_RS11290	COG3313	Fe-S protein
ICI43_RS11295	COG4989	oxidoreductase activity
ICI43_RS11300	COG2032	superoxide dismutase activity
ICI43_RS11305	COG1289	transmembrane transporter activity
ICI43_RS11310	COG1566	PFAM secretion protein HlyD family protein
ICI43_RS11325	COG3133	Outer membrane lipoprotein
ICI43_RS11335	COG3895	Periplasmic Protein
ICI43_RS11350	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ICI43_RS11355	COG0625	glutathione transferase activity
ICI43_RS11360	COG3104	oligopeptide transport
ICI43_RS11365	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ICI43_RS11370	COG4660	Part of a membrane complex involved in electron transport
ICI43_RS11375	COG4659	FMN binding
ICI43_RS11380	COG4658	electron transport chain
ICI43_RS11390	COG2878	Part of a membrane complex involved in electron transport
ICI43_RS11415	COG0673	inositol 2-dehydrogenase activity
ICI43_RS11425	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ICI43_RS11430	COG1263	PTS System
ICI43_RS11430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ICI43_RS11435	COG1609	Transcriptional regulator
ICI43_RS11440	COG1028	Short-chain dehydrogenase reductase Sdr
ICI43_RS11445	COG1309	transcriptional regulator
ICI43_RS11450	COG3250	beta-galactosidase activity
ICI43_RS11465	COG5339	Protein conserved in bacteria
ICI43_RS11470	COG1482	cell wall glycoprotein biosynthetic process
ICI43_RS11475	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ICI43_RS11475	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ICI43_RS11480	COG0114	fumarate hydratase activity
ICI43_RS11490	COG2205	protein histidine kinase activity
ICI43_RS11495	COG0745	RESPONSE REGULATOR receiver
ICI43_RS11500	COG3136	membrane protein required for alginate biosynthesis
ICI43_RS11505	COG1028	Short-chain dehydrogenase reductase Sdr
ICI43_RS11510	COG0531	amino acid
ICI43_RS11520	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ICI43_RS11525	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ICI43_RS11530	COG0628	permease
ICI43_RS11535	COG2076	Multidrug Resistance protein
ICI43_RS11540	COG2076	Multidrug Resistance protein
ICI43_RS11545	COG3591	Belongs to the peptidase S1B family
ICI43_RS11560	COG2814	Major facilitator Superfamily
ICI43_RS11565	COG0583	DNA-binding transcription factor activity
ICI43_RS11570	COG1940	carbohydrate kinase activity
ICI43_RS11575	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ICI43_RS11585	COG3381	protein complex oligomerization
ICI43_RS11590	COG3302	dmso reductase anchor subunit
ICI43_RS11595	COG0437	4 iron, 4 sulfur cluster binding
ICI43_RS11600	COG0243	molybdopterin cofactor binding
ICI43_RS11605	COG0243	molybdopterin cofactor binding
ICI43_RS11620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ICI43_RS11635	COG4948	Mandelate Racemase Muconate Lactonizing
ICI43_RS11640	COG1063	alcohol dehydrogenase
ICI43_RS11650	COG0582	viral genome integration into host DNA
ICI43_RS11660	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ICI43_RS11685	COG1396	sequence-specific DNA binding
ICI43_RS11700	COG1846	Transcriptional regulator
ICI43_RS11730	COG1403	HNH endonuclease
ICI43_RS11735	COG0484	heat shock protein binding
ICI43_RS11745	COG1278	Cold shock
ICI43_RS11760	COG3772	lysozyme
ICI43_RS11770	COG1278	Cold shock
ICI43_RS11795	COG5562	phage envelope protein
ICI43_RS11825	COG0740	serine-type endopeptidase activity
ICI43_RS11900	COG5301	cellulose 1,4-beta-cellobiosidase activity
ICI43_RS11905	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ICI43_RS11910	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ICI43_RS11930	COG0246	Mannitol dehydrogenase
ICI43_RS11940	COG1802	Transcriptional regulator
ICI43_RS11945	COG4221	oxidoreductase activity
ICI43_RS11950	COG0339	signal peptide processing
ICI43_RS11955	COG3111	PFAM Bacterial OB fold (BOF) protein
ICI43_RS11960	COG3706	GGDEF domain
ICI43_RS11970	COG2814	Major facilitator Superfamily
ICI43_RS11975	COG0697	spore germination
ICI43_RS11980	COG2188	Transcriptional regulator
ICI43_RS11990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ICI43_RS11995	COG1447	Phosphotransferase system cellobiose-specific component IIA
ICI43_RS12005	COG2723	6-phospho-beta-galactosidase activity
ICI43_RS12015	COG4977	sequence-specific DNA binding
ICI43_RS12020	COG1846	Transcriptional regulator
ICI43_RS12040	COG0583	DNA-binding transcription factor activity
ICI43_RS12050	COG2066	Belongs to the glutaminase family
ICI43_RS12060	COG2199	diguanylate cyclase activity
ICI43_RS12070	COG3781	membrane
ICI43_RS12075	COG4106	trans-aconitate 2-methyltransferase activity
ICI43_RS12080	COG1396	sequence-specific DNA binding
ICI43_RS12085	COG3550	peptidyl-serine autophosphorylation
ICI43_RS12100	COG0702	epimerase
ICI43_RS12105	COG3539	Fimbrial protein
ICI43_RS12115	COG3188	usher protein
ICI43_RS12120	COG3539	Fimbrial protein
ICI43_RS12125	COG3539	Fimbrial protein
ICI43_RS12130	COG3539	Fimbrial protein
ICI43_RS12135	COG0243	molybdopterin cofactor binding
ICI43_RS12145	COG2207	Transcriptional regulator
ICI43_RS12150	COG3119	arylsulfatase activity
ICI43_RS12155	COG0641	radical SAM
ICI43_RS12165	COG4178	(ABC) transporter
ICI43_RS12170	COG4771	TonB-dependent receptor
ICI43_RS12175	COG0612	Peptidase, M16
ICI43_RS12180	COG0076	glutamate decarboxylase activity
ICI43_RS12185	COG0531	amino acid
ICI43_RS12190	COG1649	PFAM Uncharacterised BCR, COG1649
ICI43_RS12200	COG2202	Pas domain
ICI43_RS12200	COG2199	diguanylate cyclase activity
ICI43_RS12200	COG2200	EAL domain
ICI43_RS12205	COG1764	response to oxidative stress
ICI43_RS12220	COG0281	malic enzyme
ICI43_RS12225	COG1064	alcohol dehydrogenase
ICI43_RS12235	COG3093	addiction module antidote protein HigA
ICI43_RS12240	COG2864	formate dehydrogenase
ICI43_RS12245	COG0437	4 iron, 4 sulfur cluster binding
ICI43_RS12255	COG0697	spore germination
ICI43_RS12260	COG2223	nitrite transmembrane transporter activity
ICI43_RS12265	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ICI43_RS12270	COG1140	nitrate reductase beta subunit
ICI43_RS12275	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ICI43_RS12280	COG2181	nitrate reductase activity
ICI43_RS12285	COG0384	phenazine biosynthesis protein PhzF
ICI43_RS12290	COG2162	N-hydroxyarylamine O-acetyltransferase activity
ICI43_RS12295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ICI43_RS12325	COG3501	Rhs element vgr protein
ICI43_RS12350	COG3501	Rhs element vgr protein
ICI43_RS12360	COG0625	glutathione transferase activity
ICI43_RS12365	COG0625	glutathione transferase activity
ICI43_RS12370	COG1113	amino acid transport
ICI43_RS12375	COG3391	amine dehydrogenase activity
ICI43_RS12380	COG4772	TonB-dependent receptor
ICI43_RS12390	COG1247	-acetyltransferase
ICI43_RS12395	COG3238	Protein conserved in bacteria
ICI43_RS12420	COG1177	transmembrane transport
ICI43_RS12425	COG1176	ABC-type spermidine putrescine transport system, permease component I
ICI43_RS12430	COG3842	ATPase activity
ICI43_RS12435	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ICI43_RS12440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ICI43_RS12455	COG0826	peptidase U32
ICI43_RS12460	COG1396	sequence-specific DNA binding
ICI43_RS12465	COG3135	benzoate transporter
ICI43_RS12475	COG0500	methyltransferase
ICI43_RS12480	COG1275	C4-dicarboxylate transporter malic acid transport protein
ICI43_RS12485	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ICI43_RS12490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ICI43_RS12495	COG2841	Protein conserved in bacteria
ICI43_RS12505	COG5383	Protein conserved in bacteria
ICI43_RS12510	COG0583	DNA-binding transcription factor activity
ICI43_RS12530	COG3038	cytochrome b561
ICI43_RS12535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ICI43_RS12540	COG1012	belongs to the aldehyde dehydrogenase family
ICI43_RS12545	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ICI43_RS12550	COG1643	Atp-dependent helicase
ICI43_RS12555	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ICI43_RS12560	COG0671	phosphoesterase, PA-phosphatase related
ICI43_RS12560	COG2453	phosphatase
ICI43_RS12565	COG2267	carboxylic ester hydrolase activity
ICI43_RS12570	COG4589	Belongs to the CDS family
ICI43_RS12575	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ICI43_RS12580	COG0667	Aldo Keto reductase
ICI43_RS12590	COG3784	Protein of unknown function (DUF1318)
ICI43_RS12600	COG2911	Protein conserved in bacteria
ICI43_RS12605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICI43_RS12610	COG3187	Heat shock protein
ICI43_RS12615	COG3042	response to heat
ICI43_RS12620	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ICI43_RS12620	COG0674	pyruvate-flavodoxin oxidoreductase activity
ICI43_RS12620	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ICI43_RS12620	COG1013	pyruvate-flavodoxin oxidoreductase activity
ICI43_RS12625	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ICI43_RS12630	COG0589	response to stress
ICI43_RS12655	COG0513	Belongs to the DEAD box helicase family
ICI43_RS12665	COG3706	GGDEF domain
ICI43_RS12670	COG2840	Smr protein MutS2
ICI43_RS12680	COG1566	PFAM secretion protein HlyD family protein
ICI43_RS12685	COG2207	Transcriptional regulator
ICI43_RS12695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ICI43_RS12700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ICI43_RS12705	COG0589	response to stress
ICI43_RS12710	COG3182	Iron-regulated membrane protein
ICI43_RS12715	COG0668	transmembrane transport
ICI43_RS12720	COG4166	transmembrane transport
ICI43_RS12725	COG0583	DNA-binding transcription factor activity
ICI43_RS12730	COG1073	alpha beta
ICI43_RS12735	COG0702	epimerase
ICI43_RS12745	COG4948	Mandelate Racemase Muconate Lactonizing
ICI43_RS12750	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ICI43_RS12755	COG3283	Transcriptional regulator of aromatic amino acids metabolism
ICI43_RS12765	COG3106	COG3106 Predicted ATPase
ICI43_RS12770	COG1609	Transcriptional regulator
ICI43_RS12780	COG3842	ATPase activity
ICI43_RS12785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ICI43_RS12790	COG1554	hydrolase, family 65, central catalytic
ICI43_RS12795	COG0673	inositol 2-dehydrogenase activity
ICI43_RS12800	COG1082	Xylose isomerase domain protein TIM barrel
ICI43_RS12805	COG1063	alcohol dehydrogenase
ICI43_RS12810	COG0395	ABC-type sugar transport system, permease component
ICI43_RS12815	COG1175	transmembrane transport
ICI43_RS12820	COG1653	transport
ICI43_RS12825	COG0366	Alpha amylase catalytic
ICI43_RS12830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ICI43_RS12840	COG1983	PspC domain protein
ICI43_RS12850	COG1842	Phage shock protein A
ICI43_RS12855	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ICI43_RS12870	COG4166	transmembrane transport
ICI43_RS12875	COG4168	peptide transport system, permease
ICI43_RS12880	COG4171	peptide transport system, permease
ICI43_RS12885	COG4172	Belongs to the ABC transporter superfamily
ICI43_RS12890	COG4172	Belongs to the ABC transporter superfamily
ICI43_RS12895	COG2814	Major facilitator Superfamily
ICI43_RS12905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICI43_RS12910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICI43_RS12920	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ICI43_RS12925	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ICI43_RS12925	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ICI43_RS12940	COG5001	Diguanylate cyclase
ICI43_RS12950	COG1349	DNA-binding transcription factor activity
ICI43_RS12960	COG0023	Translation Initiation Factor
ICI43_RS12970	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ICI43_RS12975	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ICI43_RS12980	COG0671	phosphoesterase, PA-phosphatase related
ICI43_RS12990	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ICI43_RS13010	COG0583	DNA-binding transcription factor activity
ICI43_RS13015	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ICI43_RS13025	COG0616	signal peptide processing
ICI43_RS13030	COG1028	Short-chain dehydrogenase reductase Sdr
ICI43_RS13035	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ICI43_RS13040	COG1187	pseudouridine synthase activity
ICI43_RS13045	COG4907	membrane protein (DUF2207)
ICI43_RS13050	COG0009	L-threonylcarbamoyladenylate synthase
ICI43_RS13055	COG0613	PHP domain protein
ICI43_RS13065	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ICI43_RS13070	COG0512	Glutamine amidotransferase of anthranilate synthase
ICI43_RS13070	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ICI43_RS13075	COG0135	phosphoribosylanthranilate isomerase activity
ICI43_RS13075	COG0134	indole-3-glycerol-phosphate synthase activity
ICI43_RS13085	COG0159	tryptophan synthase activity
ICI43_RS13090	COG3685	Protein conserved in bacteria
ICI43_RS13095	COG3685	Protein conserved in bacteria
ICI43_RS13100	COG3047	cAMP biosynthetic process
ICI43_RS13120	COG1607	acyl-coa hydrolase
ICI43_RS13130	COG2350	Protein conserved in bacteria
ICI43_RS13135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ICI43_RS13155	COG4608	Belongs to the ABC transporter superfamily
ICI43_RS13160	COG0444	Belongs to the ABC transporter superfamily
ICI43_RS13165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICI43_RS13170	COG0601	transmembrane transport
ICI43_RS13175	COG4166	transmembrane transport
ICI43_RS13185	COG2095	MarC family integral membrane protein
ICI43_RS13190	COG1454	alcohol dehydrogenase
ICI43_RS13190	COG1012	belongs to the aldehyde dehydrogenase family
ICI43_RS13200	COG1435	thymidine kinase activity
ICI43_RS13210	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ICI43_RS13215	COG0745	RESPONSE REGULATOR receiver
ICI43_RS13220	COG1752	Esterase of the alpha-beta hydrolase superfamily
ICI43_RS13230	COG0788	formyltetrahydrofolate deformylase activity
ICI43_RS13275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ICI43_RS13280	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ICI43_RS13285	COG2181	nitrate reductase activity
ICI43_RS13290	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ICI43_RS13295	COG1140	nitrate reductase beta subunit
ICI43_RS13300	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ICI43_RS13305	COG2223	nitrite transmembrane transporter activity
ICI43_RS13310	COG3850	Histidine kinase
ICI43_RS13315	COG2197	response regulator
ICI43_RS13320	COG4932	domain protein
ICI43_RS13325	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ICI43_RS13330	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
ICI43_RS13335	COG4572	Cation transport regulator
ICI43_RS13340	COG0387	Pfam Sodium calcium exchanger
ICI43_RS13355	COG2912	Transglutaminase-like superfamily
ICI43_RS13360	COG3094	Invasion gene expression up-regulator, SirB
ICI43_RS13365	COG2890	protein-(glutamine-N5) methyltransferase activity
ICI43_RS13380	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ICI43_RS13385	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ICI43_RS13390	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ICI43_RS13395	COG0659	secondary active sulfate transmembrane transporter activity
ICI43_RS13410	COG0012	GTP binding
ICI43_RS13420	COG3284	Transcriptional regulator
ICI43_RS13425	COG2376	Dihydroxyacetone kinase
ICI43_RS13430	COG1461	Dihydroxyacetone kinase
ICI43_RS13435	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ICI43_RS13435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICI43_RS13435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ICI43_RS13440	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
ICI43_RS13445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ICI43_RS13450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICI43_RS13455	COG1120	ATPase activity
ICI43_RS13460	COG0500	methyltransferase
ICI43_RS13465	COG0157	Belongs to the NadC ModD family
ICI43_RS13480	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ICI43_RS13490	COG1619	proteins homologs of microcin C7 resistance protein MccF
ICI43_RS13500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ICI43_RS13510	COG2719	SpoVR family
ICI43_RS13520	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ICI43_RS13530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ICI43_RS13535	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ICI43_RS13550	COG0179	Fumarylacetoacetate (FAA) hydrolase
ICI43_RS13575	COG2894	cell division
ICI43_RS13655	COG2200	EAL domain
ICI43_RS13660	COG0789	Transcriptional regulator
ICI43_RS13665	COG5562	phage envelope protein
ICI43_RS13675	COG0538	isocitrate dehydrogenase activity
ICI43_RS13690	COG1121	(ABC) transporter
ICI43_RS13695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ICI43_RS13700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ICI43_RS13715	COG5301	cellulose 1,4-beta-cellobiosidase activity
ICI43_RS13745	COG1196	nuclear chromosome segregation
ICI43_RS13815	COG4220	transposase activity
ICI43_RS13840	COG3772	lysozyme
ICI43_RS14055	COG0582	viral genome integration into host DNA
ICI43_RS14060	COG0538	isocitrate dehydrogenase activity
ICI43_RS14065	COG1187	pseudouridine synthase activity
ICI43_RS14085	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ICI43_RS14095	COG2205	protein histidine kinase activity
ICI43_RS14100	COG2850	peptidyl-arginine hydroxylation
ICI43_RS14110	COG3842	ATPase activity
ICI43_RS14125	COG0500	methyltransferase
ICI43_RS14130	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ICI43_RS14135	COG5301	cellulose 1,4-beta-cellobiosidase activity
ICI43_RS14240	COG4220	transposase activity
ICI43_RS14270	COG3772	lysozyme
ICI43_RS14320	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ICI43_RS14325	COG1403	HNH endonuclease
ICI43_RS14385	COG1846	Transcriptional regulator
ICI43_RS14390	COG1484	DNA-dependent DNA replication
ICI43_RS14395	COG1846	Transcriptional regulator
ICI43_RS14450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ICI43_RS14460	COG0582	viral genome integration into host DNA
ICI43_RS14465	COG1177	transmembrane transport
ICI43_RS14470	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ICI43_RS14480	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ICI43_RS14485	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ICI43_RS14490	COG1940	carbohydrate kinase activity
ICI43_RS14495	COG4591	ABC-type transport system involved in lipoprotein release permease component
ICI43_RS14505	COG4591	ABC-type transport system involved in lipoprotein release permease component
ICI43_RS14510	COG4763	Acyl-transferase
ICI43_RS14515	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ICI43_RS14520	COG1388	LysM domain
ICI43_RS14520	COG1376	ErfK ybiS ycfS ynhG family protein
ICI43_RS14530	COG1309	transcriptional regulator
ICI43_RS14535	COG3134	Outer membrane lipoprotein
ICI43_RS14540	COG1252	NADH dehydrogenase
ICI43_RS14550	COG1472	Belongs to the glycosyl hydrolase 3 family
ICI43_RS14555	COG0510	thiamine kinase activity
ICI43_RS14560	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
ICI43_RS14565	COG5633	Lipoprotein
ICI43_RS14570	COG0537	adenosine 5'-monophosphoramidase activity
ICI43_RS14575	COG4773	Receptor
ICI43_RS14580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ICI43_RS14580	COG1263	PTS System
ICI43_RS14585	COG0084	hydrolase, TatD family'
ICI43_RS14590	COG0470	DNA polymerase III
ICI43_RS14595	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ICI43_RS14600	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ICI43_RS14605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ICI43_RS14610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ICI43_RS14620	COG1028	Short-chain dehydrogenase reductase Sdr
ICI43_RS14625	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ICI43_RS14645	COG1399	metal-binding, possibly nucleic acid-binding protein
ICI43_RS14650	COG0424	maF-like protein
ICI43_RS14655	COG0564	pseudouridine synthase activity
ICI43_RS14660	COG1530	ribonuclease E activity
ICI43_RS14665	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ICI43_RS14670	COG1256	bacterial-type flagellum assembly
ICI43_RS14675	COG3951	Flagellar rod assembly protein muramidase FlgJ
ICI43_RS14675	COG1705	Flagellar rod assembly protein muramidase FlgJ
ICI43_RS14680	COG1706	bacterial-type flagellum-dependent cell motility
ICI43_RS14690	COG4786	Flagellar basal body rod
ICI43_RS14695	COG4787	bacterial-type flagellum-dependent cell motility
ICI43_RS14700	COG1749	Flagellar hook protein flgE
ICI43_RS14705	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ICI43_RS14710	COG1558	bacterial-type flagellum-dependent cell motility
ICI43_RS14715	COG1815	bacterial-type flagellum-dependent cell motility
ICI43_RS14720	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
ICI43_RS14725	COG2747	anti-sigma28 factor FlgM
ICI43_RS14730	COG3418	PFAM FlgN family protein
ICI43_RS14735	COG0728	peptidoglycan biosynthetic process
ICI43_RS14740	COG0673	inositol 2-dehydrogenase activity
ICI43_RS14750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ICI43_RS14760	COG2999	glutathione oxidoreductase activity
ICI43_RS14770	COG0418	dihydroorotase activity
ICI43_RS14785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ICI43_RS14795	COG3038	cytochrome b561
ICI43_RS14800	COG2353	YceI-like domain
ICI43_RS14810	COG1560	Kdo2-lipid A biosynthetic process
ICI43_RS14825	COG5645	(Lipo)protein
ICI43_RS14830	COG2943	transferase activity, transferring hexosyl groups
ICI43_RS14845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICI43_RS14850	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ICI43_RS14875	COG2197	response regulator
ICI43_RS14890	COG1462	curli production assembly transport component CsgG
ICI43_RS14900	COG3381	protein complex oligomerization
ICI43_RS14910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ICI43_RS14955	COG2003	Belongs to the UPF0758 family
ICI43_RS14980	COG2020	methyltransferase activity
ICI43_RS14985	COG3468	outer membrane autotransporter barrel domain protein
ICI43_RS15030	COG0523	cobalamin synthesis protein
ICI43_RS15040	COG4771	TonB-dependent receptor
ICI43_RS15085	COG2382	esterase
ICI43_RS15090	COG2819	hydrolase of the alpha beta superfamily
ICI43_RS15095	COG4771	TonB-dependent receptor
ICI43_RS15100	COG3335	DDE superfamily endonuclease
ICI43_RS15140	COG3539	Fimbrial protein
ICI43_RS15195	COG2994	toxin metabolic process
ICI43_RS15220	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ICI43_RS15225	COG4644	lycopene metabolic process
ICI43_RS15270	COG3210	domain, Protein
ICI43_RS15275	COG3210	domain, Protein
ICI43_RS15305	COG0204	Acyl-transferase
ICI43_RS15315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICI43_RS15330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ICI43_RS15335	COG1216	Glycosyl transferase, family 2
ICI43_RS15360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ICI43_RS15370	COG1028	Short-chain dehydrogenase reductase Sdr
ICI43_RS15375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ICI43_RS15395	COG2222	sugar isomerase
ICI43_RS15405	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ICI43_RS15430	COG4983	Phage plasmid primase, P4 family domain protein
ICI43_RS15455	COG0582	viral genome integration into host DNA
ICI43_RS15460	COG3706	GGDEF domain
ICI43_RS15465	COG0457	Tetratricopeptide repeat
ICI43_RS15470	COG0726	polysaccharide deacetylase
ICI43_RS15470	COG1649	PFAM Uncharacterised BCR, COG1649
ICI43_RS15475	COG1215	transferase activity, transferring glycosyl groups
ICI43_RS15480	COG3658	cytochrome
ICI43_RS15485	COG1702	phosphate starvation-inducible protein PhoH
ICI43_RS15495	COG2822	iron ion transport
ICI43_RS15500	COG0672	)-iron permease
ICI43_RS15505	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ICI43_RS15515	COG0506	proline dehydrogenase activity
ICI43_RS15515	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ICI43_RS15515	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ICI43_RS15520	COG1309	transcriptional regulator
ICI43_RS15525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICI43_RS15530	COG1335	isochorismatase
ICI43_RS15540	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ICI43_RS15545	COG0778	Nitroreductase
ICI43_RS15550	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ICI43_RS15555	COG2233	PERMEase
ICI43_RS15560	COG3729	General stress protein
ICI43_RS15590	COG3381	protein complex oligomerization
ICI43_RS15595	COG0243	molybdopterin cofactor binding
ICI43_RS15600	COG3005	denitrification pathway
ICI43_RS15605	COG0745	RESPONSE REGULATOR receiver
ICI43_RS15610	COG1879	ABC-type sugar transport system periplasmic component
ICI43_RS15615	COG2198	Histidine kinase
ICI43_RS15615	COG0784	Response regulator, receiver
ICI43_RS15615	COG2205	protein histidine kinase activity
ICI43_RS15620	COG0348	domain, Protein
ICI43_RS15640	COG1278	Cold shock
ICI43_RS15645	COG1278	Cold shock
ICI43_RS15660	COG1294	oxidase, subunit
ICI43_RS15665	COG1271	oxidase subunit
ICI43_RS15670	COG1773	rubredoxin
ICI43_RS15675	COG1999	signal sequence binding
ICI43_RS15680	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ICI43_RS15685	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
ICI43_RS15690	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ICI43_RS15695	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ICI43_RS15705	COG0670	Belongs to the BI1 family
ICI43_RS15710	COG2920	part of a sulfur-relay system
ICI43_RS15715	COG1254	Belongs to the acylphosphatase family
ICI43_RS15730	COG1832	CoA-binding protein
ICI43_RS15745	COG0210	DNA helicase
ICI43_RS15750	COG3304	Inner membrane component domain
ICI43_RS15755	COG1289	transmembrane transporter activity
ICI43_RS15760	COG3070	regulator of competence-specific genes
ICI43_RS15780	COG1067	ATP-dependent peptidase activity
ICI43_RS15790	COG3130	regulation of translation
ICI43_RS15795	COG3009	Protein conserved in bacteria
ICI43_RS15800	COG3008	intermembrane lipid transfer
ICI43_RS15800	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ICI43_RS15805	COG2995	paraquat-inducible protein a
ICI43_RS15810	COG0488	(ABC) transporter
ICI43_RS15815	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ICI43_RS15815	COG0116	Belongs to the methyltransferase superfamily
ICI43_RS15820	COG3217	Mosc domain protein beta barrel domain protein
ICI43_RS15820	COG0633	Ferredoxin
ICI43_RS15835	COG0431	NADPH-dependent FMN reductase
ICI43_RS15840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ICI43_RS15850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ICI43_RS15855	COG1116	anion transmembrane transporter activity
ICI43_RS15860	COG0308	aminopeptidase N
ICI43_RS15880	COG1448	Aminotransferase
ICI43_RS15885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ICI43_RS15890	COG3108	Peptidase M15
ICI43_RS15895	COG2989	Protein conserved in bacteria
ICI43_RS15900	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ICI43_RS15905	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ICI43_RS15915	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ICI43_RS15920	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ICI43_RS15925	COG3173	Aminoglycoside phosphotransferase
ICI43_RS15930	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ICI43_RS15940	COG3214	Protein conserved in bacteria
ICI43_RS15955	COG2333	competence protein COMEC
ICI43_RS15955	COG0658	competence protein
ICI43_RS15965	COG0539	negative regulation of cytoplasmic translation
ICI43_RS15975	COG0501	Belongs to the peptidase M48B family
ICI43_RS15980	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ICI43_RS15990	COG2323	membrane
ICI43_RS15995	COG1944	ATP diphosphatase activity
ICI43_RS16000	COG2116	formate transmembrane transporter activity
ICI43_RS16005	COG1882	Formate acetyltransferase
ICI43_RS16010	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ICI43_RS16020	COG1335	isochorismatase
ICI43_RS16025	COG3302	dmso reductase anchor subunit
ICI43_RS16030	COG0437	4 iron, 4 sulfur cluster binding
ICI43_RS16035	COG0243	molybdopterin cofactor binding
ICI43_RS16045	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ICI43_RS16055	COG1674	ftsk spoiiie
ICI43_RS16055	COG1178	ABC-type Fe3 transport system permease component
ICI43_RS16060	COG1522	sequence-specific DNA binding
ICI43_RS16065	COG0492	ferredoxin-NADP+ reductase activity
ICI43_RS16070	COG4988	ABC transporter
ICI43_RS16075	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ICI43_RS16095	COG0542	response to heat
ICI43_RS16105	COG1278	Cold shock
ICI43_RS16115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICI43_RS16120	COG2990	Protein conserved in bacteria
ICI43_RS16125	COG3593	DNA synthesis involved in DNA repair
ICI43_RS16135	COG2431	L-lysine efflux transmembrane transporter activity
ICI43_RS16140	COG1151	hydroxylamine reductase activity
ICI43_RS16145	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ICI43_RS16150	COG0028	Belongs to the TPP enzyme family
ICI43_RS16155	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ICI43_RS16160	COG0702	epimerase
ICI43_RS16165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ICI43_RS16170	COG3023	N-Acetylmuramoyl-L-alanine amidase
ICI43_RS16185	COG1126	abc transporter atp-binding protein
ICI43_RS16190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICI43_RS16195	COG4215	(ABC) transporter
ICI43_RS16200	COG4160	amino acid transport
ICI43_RS16205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICI43_RS16210	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICI43_RS16220	COG1177	transmembrane transport
ICI43_RS16225	COG1176	ABC-type spermidine putrescine transport system, permease component I
ICI43_RS16230	COG3842	ATPase activity
ICI43_RS16235	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ICI43_RS16250	COG0778	Nitroreductase
ICI43_RS16260	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ICI43_RS16275	COG3226	Transcriptional regulator
ICI43_RS16280	COG0738	Major facilitator superfamily
ICI43_RS16285	COG0561	phosphatase activity
ICI43_RS16295	COG2814	Major facilitator Superfamily
ICI43_RS16300	COG0671	phosphoesterase, PA-phosphatase related
ICI43_RS16305	COG1349	DNA-binding transcription factor activity
ICI43_RS16310	COG1686	Belongs to the peptidase S11 family
ICI43_RS16315	COG0625	glutathione transferase activity
ICI43_RS16320	COG2133	pyrroloquinoline quinone binding
ICI43_RS16335	COG2199	diguanylate cyclase activity
ICI43_RS16340	COG2200	EAL domain
ICI43_RS16360	COG4172	Belongs to the ABC transporter superfamily
ICI43_RS16365	COG1446	asparaginase
ICI43_RS16370	COG0303	'Molybdopterin
ICI43_RS16375	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ICI43_RS16380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ICI43_RS16385	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ICI43_RS16390	COG1882	Formate acetyltransferase
ICI43_RS16395	COG0561	phosphatase activity
ICI43_RS16400	COG0488	(ABC) transporter
ICI43_RS16405	COG1376	ErfK ybiS ycfS ynhG family protein
ICI43_RS16410	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ICI43_RS16415	COG1321	iron dependent repressor
ICI43_RS16425	COG2194	sulfuric ester hydrolase activity
ICI43_RS16430	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ICI43_RS16440	COG5006	permease, DMT superfamily
ICI43_RS16445	COG0783	Belongs to the Dps family
ICI43_RS16450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICI43_RS16455	COG0765	amino acid transport
ICI43_RS16460	COG1126	abc transporter atp-binding protein
ICI43_RS16465	COG0668	transmembrane transport
ICI43_RS16470	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
ICI43_RS16480	COG4774	siderophore transport
ICI43_RS16485	COG3128	pkhd-type hydroxylase
ICI43_RS16490	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ICI43_RS16500	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ICI43_RS16505	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ICI43_RS16510	COG1199	ATP-dependent helicase activity
ICI43_RS16520	COG0513	Belongs to the DEAD box helicase family
ICI43_RS16525	COG1309	transcriptional regulator
ICI43_RS16535	COG1131	(ABC) transporter
ICI43_RS16540	COG0842	Transport permease protein
ICI43_RS16545	COG0842	Transport permease protein
ICI43_RS16555	COG3568	Endonuclease Exonuclease Phosphatase
ICI43_RS16560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICI43_RS16565	COG0392	lysyltransferase activity
ICI43_RS16570	COG0670	Belongs to the BI1 family
ICI43_RS16575	COG0670	Belongs to the BI1 family
ICI43_RS16580	COG0314	molybdopterin synthase activity
ICI43_RS16585	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ICI43_RS16595	COG0521	Mo-molybdopterin cofactor biosynthetic process
ICI43_RS16605	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ICI43_RS16615	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ICI43_RS16620	COG2226	methyltransferase
ICI43_RS16625	COG0156	8-amino-7-oxononanoate synthase activity
ICI43_RS16635	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ICI43_RS16645	COG1881	PFAM PEBP family protein
ICI43_RS16650	COG4677	pectinesterase activity
ICI43_RS16655	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ICI43_RS16660	COG0471	metal ion transport
ICI43_RS16665	COG2828	Protein conserved in bacteria
ICI43_RS16670	COG0583	DNA-binding transcription factor activity
ICI43_RS16680	COG0561	phosphatase activity
ICI43_RS16685	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ICI43_RS16690	COG4149	molybdate abc transporter
ICI43_RS16695	COG0725	ABC transporter, periplasmic molybdate-binding protein
ICI43_RS16705	COG2005	Transcriptional regulator
ICI43_RS16705	COG3585	molybdate ion transport
ICI43_RS16710	COG1119	ATPase activity
ICI43_RS16715	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ICI43_RS16720	COG1085	galactose-1-phosphate uridylyltransferase
ICI43_RS16730	COG2017	converts alpha-aldose to the beta-anomer
ICI43_RS16740	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ICI43_RS16755	COG3201	nicotinamide mononucleotide transporter
ICI43_RS16760	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ICI43_RS16800	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ICI43_RS16805	COG2885	chlorophyll binding
ICI43_RS16815	COG3064	Membrane
ICI43_RS16820	COG0848	biopolymer transport protein
ICI43_RS16825	COG0811	peptide transport
ICI43_RS16830	COG0824	Thioesterase
ICI43_RS16835	COG3790	cyd operon protein YbgE
ICI43_RS16840	COG4890	Cyd operon protein YbgT
ICI43_RS16845	COG1294	oxidase, subunit
ICI43_RS16850	COG1271	oxidase subunit
ICI43_RS16860	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ICI43_RS16870	COG0508	dehydrogenase complex catalyzes the overall conversion of
ICI43_RS16875	COG0567	Dehydrogenase, E1 component
ICI43_RS16880	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ICI43_RS16885	COG1053	succinate dehydrogenase
ICI43_RS16890	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ICI43_RS16895	COG2009	succinate dehydrogenase
ICI43_RS16905	COG0372	Belongs to the citrate synthase family
ICI43_RS16915	COG3180	Ammonia monooxygenase
ICI43_RS16925	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ICI43_RS16930	COG1984	allophanate hydrolase subunit 2
ICI43_RS16935	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ICI43_RS16940	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ICI43_RS16950	COG0415	Belongs to the DNA photolyase family
ICI43_RS16955	COG3272	Protein of unknown function (DUF1722)
ICI43_RS16970	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ICI43_RS16985	COG2205	protein histidine kinase activity
ICI43_RS16990	COG0745	RESPONSE REGULATOR receiver
ICI43_RS17000	COG1982	Orn Lys Arg decarboxylase major
ICI43_RS17005	COG0531	amino acid
ICI43_RS17010	COG0033	Phosphoglucomutase
ICI43_RS17015	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ICI43_RS17020	COG0596	Alpha beta hydrolase
ICI43_RS17030	COG0716	FMN binding
ICI43_RS17040	COG0735	belongs to the Fur family
ICI43_RS17060	COG1349	DNA-binding transcription factor activity
ICI43_RS17065	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ICI43_RS17070	COG3395	kinase activity
ICI43_RS17075	COG1454	alcohol dehydrogenase
ICI43_RS17080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ICI43_RS17085	COG0861	Integral membrane protein TerC family
ICI43_RS17105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ICI43_RS17105	COG2190	(PTS) system
ICI43_RS17105	COG1263	PTS System
ICI43_RS17110	COG0363	glucosamine-6-phosphate deaminase activity
ICI43_RS17115	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ICI43_RS17120	COG1940	carbohydrate kinase activity
ICI43_RS17120	COG1846	Transcriptional regulator
ICI43_RS17125	COG0647	UMP catabolic process
ICI43_RS17130	COG0367	asparagine synthase
ICI43_RS17170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ICI43_RS17180	COG1702	phosphate starvation-inducible protein PhoH
ICI43_RS17190	COG4535	Mg2 and Co2 transporter CorC
ICI43_RS17195	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ICI43_RS17205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICI43_RS17210	COG0765	amino acid transport
ICI43_RS17215	COG0765	amino acid transport
ICI43_RS17220	COG1126	abc transporter atp-binding protein
ICI43_RS17230	COG2888	peptidyl-tyrosine sulfation
ICI43_RS17245	COG1466	dna polymerase III delta subunit
ICI43_RS17255	COG0406	alpha-ribazole phosphatase activity
ICI43_RS17260	COG0799	negative regulation of ribosome biogenesis
ICI43_RS17270	COG0768	penicillin binding
ICI43_RS17275	COG0772	Belongs to the SEDS family
ICI43_RS17280	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ICI43_RS17285	COG1686	Belongs to the peptidase S11 family
ICI43_RS17310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ICI43_RS17315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ICI43_RS17335	COG3069	C4-dicarboxylate transmembrane transporter activity
ICI43_RS17340	COG4565	transcriptional regulatory protein
ICI43_RS17345	COG3290	protein histidine kinase activity
ICI43_RS17350	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ICI43_RS17360	COG2301	Belongs to the HpcH HpaI aldolase family
ICI43_RS17365	COG3051	citrate lyase alpha subunit
ICI43_RS17380	COG0471	metal ion transport
ICI43_RS17385	COG3719	Belongs to the RNase T2 family
ICI43_RS17390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ICI43_RS17395	COG0589	response to stress
ICI43_RS17400	COG3634	alkyl hydroperoxide reductase activity
ICI43_RS17405	COG0450	alkyl hydroperoxide reductase
ICI43_RS17410	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ICI43_RS17415	COG0583	DNA-binding transcription factor activity
ICI43_RS17420	COG3969	phosphoadenosine phosphosulfate
ICI43_RS17425	COG1475	DNA binding
ICI43_RS17430	COG0436	Aminotransferase
ICI43_RS17435	COG0371	Dehydrogenase
ICI43_RS17440	COG2879	small protein
ICI43_RS17445	COG1966	Carbon starvation protein
ICI43_RS17450	COG2050	protein possibly involved in aromatic compounds catabolism
ICI43_RS17455	COG1028	Short-chain dehydrogenase reductase Sdr
ICI43_RS17460	COG1535	isochorismatase
ICI43_RS17460	COG3433	isochorismatase activity
ICI43_RS17465	COG1021	2,3-dihydroxybenzoate-AMP ligase
ICI43_RS17470	COG1169	isochorismate synthase
ICI43_RS17475	COG4592	Periplasmic binding protein
ICI43_RS17485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICI43_RS17490	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICI43_RS17495	COG1120	ATPase activity
ICI43_RS17500	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ICI43_RS17505	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ICI43_RS17505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ICI43_RS17510	COG3251	PFAM MbtH domain protein
ICI43_RS17515	COG2382	esterase
ICI43_RS17525	COG4771	TonB-dependent receptor
ICI43_RS17530	COG2977	Belongs to the P-Pant transferase superfamily
ICI43_RS17540	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ICI43_RS17550	COG2315	Protein conserved in bacteria
ICI43_RS17555	COG0778	Nitroreductase
ICI43_RS17560	COG0668	transmembrane transport
ICI43_RS17565	COG1113	amino acid transport
ICI43_RS17570	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICI43_RS17575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICI43_RS17580	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICI43_RS17585	COG1538	Outer membrane efflux protein
ICI43_RS17590	COG0745	RESPONSE REGULATOR receiver
ICI43_RS17595	COG5002	protein histidine kinase activity
ICI43_RS17605	COG4783	chaperone-mediated protein folding
ICI43_RS17615	COG4571	Outer membrane protease
ICI43_RS17620	COG0500	methyltransferase
ICI43_RS17650	COG2501	S4 domain
ICI43_RS17665	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ICI43_RS17670	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ICI43_RS17680	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ICI43_RS17685	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ICI43_RS17690	COG0549	Belongs to the carbamate kinase family
ICI43_RS17700	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ICI43_RS17705	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ICI43_RS17710	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ICI43_RS17715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ICI43_RS17720	COG3257	ureidoglycine aminohydrolase activity
ICI43_RS17725	COG1929	Belongs to the glycerate kinase type-1 family
ICI43_RS17730	COG2233	PERMEase
ICI43_RS17740	COG1953	Uracil, thiamine, allantoin
ICI43_RS17745	COG2084	Dehydrogenase
ICI43_RS17750	COG3622	Belongs to the hyi family
ICI43_RS17755	COG3960	tartronate-semialdehyde synthase activity
ICI43_RS17760	COG1414	Transcriptional regulator
ICI43_RS17765	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
ICI43_RS17780	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ICI43_RS17785	COG4181	ATPase activity
ICI43_RS17790	COG2755	lipolytic protein G-D-S-L family
ICI43_RS17795	COG0300	oxidoreductase activity
ICI43_RS17800	COG3118	belongs to the thioredoxin family
ICI43_RS17805	COG0390	transport system, permease component
ICI43_RS17810	COG4619	ABC transporter
ICI43_RS17815	COG0330	HflC and HflK could
ICI43_RS17820	COG1585	Membrane protein implicated in regulation of membrane protease activity
ICI43_RS17830	COG0789	Transcriptional regulator
ICI43_RS17835	COG0531	amino acid
ICI43_RS17840	COG2066	Belongs to the glutaminase family
ICI43_RS17845	COG2217	Heavy metal translocating P-type atpase
ICI43_RS17850	COG3093	addiction module antidote protein HigA
ICI43_RS17860	COG3735	TraB family
ICI43_RS17865	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ICI43_RS17870	COG0737	Belongs to the 5'-nucleotidase family
ICI43_RS17875	COG2223	nitrite transmembrane transporter activity
ICI43_RS17880	COG4651	solute:proton antiporter activity
ICI43_RS17880	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ICI43_RS17885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICI43_RS17890	COG0657	acetylesterase activity
ICI43_RS17920	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ICI43_RS17930	COG2832	Protein of unknown function (DUF454)
ICI43_RS17935	COG3923	Primosomal replication protein n
ICI43_RS17945	COG1196	nuclear chromosome segregation
ICI43_RS17945	COG3264	Mechanosensitive ion channel
ICI43_RS17950	COG1309	transcriptional regulator
ICI43_RS17955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICI43_RS17960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICI43_RS17975	COG0110	maltose O-acetyltransferase activity
ICI43_RS17985	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ICI43_RS17990	COG5507	3-demethylubiquinone-9 3-methyltransferase
ICI43_RS18000	COG3695	enzyme binding
ICI43_RS18005	COG3126	Type III secretion system lipoprotein chaperone (YscW)
ICI43_RS18010	COG1946	Acyl-CoA thioesterase
ICI43_RS18015	COG0004	ammonium transporteR
ICI43_RS18020	COG0347	Belongs to the P(II) protein family
ICI43_RS18025	COG1132	(ABC) transporter
ICI43_RS18030	COG1132	(ABC) transporter
ICI43_RS18035	COG1522	sequence-specific DNA binding
ICI43_RS18040	COG0561	phosphatase activity
ICI43_RS18055	COG0824	Thioesterase
ICI43_RS18060	COG1555	photosystem II stabilization
ICI43_RS18065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ICI43_RS18070	COG0776	regulation of translation
ICI43_RS18075	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ICI43_RS18095	COG0271	Belongs to the BolA IbaG family
ICI43_RS18100	COG3056	Lipoprotein
ICI43_RS18105	COG2223	nitrite transmembrane transporter activity
ICI43_RS18110	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ICI43_RS18115	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ICI43_RS18120	COG1845	cytochrome c oxidase, subunit III
ICI43_RS18125	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ICI43_RS18135	COG2814	Major facilitator Superfamily
ICI43_RS18145	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ICI43_RS18150	COG0693	protein deglycase activity
ICI43_RS18165	COG0142	geranyltranstransferase activity
ICI43_RS18175	COG0667	Aldo Keto reductase
ICI43_RS18180	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ICI43_RS18185	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ICI43_RS18200	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ICI43_RS18200	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ICI43_RS18210	COG4238	major outer membrane lipoprotein
ICI43_RS18215	COG3248	Nucleoside-binding outer membrane protein
ICI43_RS18220	COG1403	HNH endonuclease
ICI43_RS18225	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ICI43_RS18230	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ICI43_RS18235	COG1862	Preprotein translocase
ICI43_RS18245	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ICI43_RS18250	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
ICI43_RS18255	COG0366	Alpha amylase catalytic
ICI43_RS18260	COG1113	amino acid transport
ICI43_RS18265	COG1114	Component of the transport system for branched-chain amino acids
ICI43_RS18270	COG5002	protein histidine kinase activity
ICI43_RS18275	COG0745	RESPONSE REGULATOR receiver
ICI43_RS18280	COG0420	3'-5' exonuclease activity
ICI43_RS18285	COG0419	ATPase involved in DNA repair
ICI43_RS18290	COG2814	Major facilitator Superfamily
ICI43_RS18295	COG1940	carbohydrate kinase activity
ICI43_RS18320	COG4126	flavin adenine dinucleotide binding
ICI43_RS18340	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ICI43_RS18345	COG3706	GGDEF domain
ICI43_RS18355	COG1785	Belongs to the alkaline phosphatase family
ICI43_RS18370	COG1181	Belongs to the D-alanine--D-alanine ligase family
ICI43_RS18390	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
ICI43_RS18395	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ICI43_RS18400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ICI43_RS18420	COG0113	porphobilinogen synthase activity
ICI43_RS18425	COG2175	clavaminate synthase activity
ICI43_RS18430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ICI43_RS18435	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ICI43_RS18440	COG4521	taurine ABC transporter
ICI43_RS18445	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ICI43_RS18450	COG1215	transferase activity, transferring glycosyl groups
ICI43_RS18475	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ICI43_RS18480	COG3122	Protein conserved in bacteria
ICI43_RS18490	COG1609	Transcriptional regulator
ICI43_RS18495	COG3250	beta-galactosidase activity
ICI43_RS18500	COG2223	nitrite transmembrane transporter activity
ICI43_RS18505	COG0110	maltose O-acetyltransferase activity
ICI43_RS18510	COG0402	S-adenosylhomocysteine deaminase activity
ICI43_RS18515	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ICI43_RS18520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ICI43_RS18525	COG2079	MmgE PrpD family protein
ICI43_RS18530	COG0372	Belongs to the citrate synthase family
ICI43_RS18535	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ICI43_RS18540	COG3829	transcription factor binding
ICI43_RS18550	COG1280	lysine exporter protein (LysE YggA)
ICI43_RS18560	COG1064	alcohol dehydrogenase
ICI43_RS18565	COG0402	S-adenosylhomocysteine deaminase activity
ICI43_RS18570	COG0549	Belongs to the carbamate kinase family
ICI43_RS18580	COG1304	FMN binding
ICI43_RS18585	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ICI43_RS18595	COG0666	response to abiotic stimulus
ICI43_RS18605	COG0583	DNA-binding transcription factor activity
ICI43_RS18610	COG2771	luxR family
ICI43_RS18610	COG2200	EAL domain
ICI43_RS18615	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ICI43_RS18625	COG1012	belongs to the aldehyde dehydrogenase family
ICI43_RS18630	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ICI43_RS18635	COG0582	viral genome integration into host DNA
ICI43_RS18640	COG2200	EAL domain
ICI43_RS18640	COG2771	luxR family
ICI43_RS18655	COG3468	outer membrane autotransporter barrel domain protein
ICI43_RS18665	COG1556	Lactate utilization protein
ICI43_RS18670	COG1139	Iron-sulfur cluster binding protein
ICI43_RS18675	COG0247	lactate metabolic process
ICI43_RS18680	COG2207	Transcriptional regulator
ICI43_RS18685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ICI43_RS18695	COG3059	membrane
ICI43_RS18700	COG0656	L-ascorbic acid biosynthetic process
ICI43_RS18705	COG2207	Transcriptional regulator
ICI43_RS18705	COG3708	Transcriptional regulator
ICI43_RS18710	COG1388	LysM domain
ICI43_RS18715	COG0656	L-ascorbic acid biosynthetic process
ICI43_RS18720	COG0667	Aldo Keto reductase
ICI43_RS18730	COG0583	DNA-binding transcription factor activity
ICI43_RS18735	COG1073	alpha beta
ICI43_RS18740	COG1902	pentaerythritol trinitrate reductase activity
ICI43_RS18780	COG3188	usher protein
ICI43_RS18795	COG0727	PFAM Uncharacterised protein family (UPF0153)
ICI43_RS18805	COG3477	response to acidic pH
ICI43_RS18835	COG0582	viral genome integration into host DNA
ICI43_RS18845	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ICI43_RS18855	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ICI43_RS18875	COG2195	Cleaves the N-terminal amino acid of tripeptides
ICI43_RS18880	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ICI43_RS18885	COG1690	Belongs to the RtcB family
ICI43_RS18890	COG0454	-acetyltransferase
ICI43_RS18895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ICI43_RS18910	COG0791	NLP P60 protein
ICI43_RS18915	COG3034	peptidoglycan biosynthetic process
ICI43_RS18920	COG0121	glutamine amidotransferase
ICI43_RS18930	COG1960	acyl-CoA dehydrogenase activity
ICI43_RS18940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ICI43_RS18960	COG2197	response regulator
ICI43_RS19005	COG3210	domain, Protein
ICI43_RS19005	COG3468	outer membrane autotransporter barrel domain protein
ICI43_RS19025	COG3210	domain, Protein
ICI43_RS19030	COG3210	domain, Protein
ICI43_RS19060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICI43_RS19070	COG3037	sugar-specific permease SgaT UlaA
ICI43_RS19085	COG0738	Major facilitator superfamily
ICI43_RS19095	COG1349	DNA-binding transcription factor activity
ICI43_RS19125	COG2211	Major facilitator Superfamily
ICI43_RS19130	COG1917	Cupin 2, conserved barrel domain protein
ICI43_RS19135	COG1028	Short-chain dehydrogenase reductase Sdr
ICI43_RS19140	COG0823	Involved in the tonB-independent uptake of proteins
ICI43_RS19215	COG1120	ATPase activity
ICI43_RS19220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICI43_RS19245	COG0582	viral genome integration into host DNA
ICI43_RS19310	COG2003	Belongs to the UPF0758 family
ICI43_RS19350	COG3547	Transposase (IS116 IS110 IS902 family)
ICI43_RS19360	COG3436	PFAM IS66 Orf2 family protein
ICI43_RS19380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ICI43_RS19390	COG2226	methyltransferase
ICI43_RS19395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ICI43_RS19400	COG0741	lytic transglycosylase activity
ICI43_RS19400	COG1388	LysM domain
ICI43_RS19405	COG2226	methyltransferase
ICI43_RS19415	COG0583	DNA-binding transcription factor activity
ICI43_RS19420	COG0656	L-ascorbic acid biosynthetic process
ICI43_RS19455	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ICI43_RS19460	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ICI43_RS19465	COG2011	ABC-type metal ion transport system permease component
ICI43_RS19470	COG1464	Belongs to the NlpA lipoprotein family
ICI43_RS19480	COG1720	tRNA m6t6A37 methyltransferase activity
ICI43_RS19490	COG0791	NLP P60 protein
ICI43_RS19500	COG3015	lipoprotein NlpE involved in copper resistance
ICI43_RS19505	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ICI43_RS19510	COG4681	YaeQ
ICI43_RS19520	COG4568	rho-dependent transcription termination
ICI43_RS19525	COG0037	tRNA processing
ICI43_RS19530	COG0346	lactoylglutathione lyase activity
ICI43_RS19535	COG1982	Orn Lys Arg decarboxylase major
ICI43_RS19545	COG0587	DNA-directed DNA polymerase activity
ICI43_RS19550	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ICI43_RS19570	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ICI43_RS19575	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ICI43_RS19585	COG0750	zinc metalloprotease
ICI43_RS19590	COG0575	Belongs to the CDS family
ICI43_RS19595	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ICI43_RS19600	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ICI43_RS19625	COG0024	Methionine aminopeptidase
ICI43_RS19630	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ICI43_RS19635	COG2171	N-acyltransferase activity
ICI43_RS19645	COG3835	regulator
ICI43_RS19650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ICI43_RS19665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ICI43_RS19670	COG2860	membrane
ICI43_RS19695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICI43_RS19700	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ICI43_RS19705	COG1120	ATPase activity
ICI43_RS19710	COG4774	siderophore transport
ICI43_RS19715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ICI43_RS19720	COG1643	Atp-dependent helicase
ICI43_RS19725	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ICI43_RS19735	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ICI43_RS19740	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ICI43_RS19745	COG0617	tRNA 3'-terminal CCA addition
ICI43_RS19750	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ICI43_RS19755	COG3539	Fimbrial protein
ICI43_RS19760	COG3121	Chaperone
ICI43_RS19765	COG3188	usher protein
ICI43_RS19770	COG3539	Fimbrial protein
ICI43_RS19775	COG3539	Fimbrial protein
ICI43_RS19780	COG3539	Fimbrial protein
ICI43_RS19785	COG3539	Fimbrial protein
ICI43_RS19795	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ICI43_RS19805	COG5464	transposase or invertase
ICI43_RS19815	COG0726	polysaccharide deacetylase
ICI43_RS19820	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICI43_RS19825	COG0842	Transport permease protein
ICI43_RS19830	COG1131	(ABC) transporter
ICI43_RS19835	COG0288	reversible hydration of carbon dioxide
ICI43_RS19840	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ICI43_RS19845	COG4993	Dehydrogenase
ICI43_RS19850	COG2132	Multicopper oxidase
ICI43_RS19875	COG1049	propionate catabolic process, 2-methylcitrate cycle
ICI43_RS19880	COG3064	Membrane
ICI43_RS19885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ICI43_RS19890	COG0508	dehydrogenase complex catalyzes the overall conversion of
ICI43_RS19895	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ICI43_RS19900	COG2186	Transcriptional regulator
ICI43_RS19925	COG3157	Type VI secretion system effector, Hcp
ICI43_RS19930	COG1113	amino acid transport
ICI43_RS19935	COG3725	Membrane protein required for beta-lactamase induction
ICI43_RS19940	COG3023	N-Acetylmuramoyl-L-alanine amidase
ICI43_RS19945	COG0157	Belongs to the NadC ModD family
ICI43_RS19950	COG4969	Belongs to the N-Me-Phe pilin family
ICI43_RS19955	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ICI43_RS19960	COG1459	type II secretion system
ICI43_RS19975	COG0237	dephospho-CoA kinase activity
ICI43_RS19985	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ICI43_RS19995	COG0494	nUDIX hydrolase
ICI43_RS20015	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ICI43_RS20020	COG0849	cell division
ICI43_RS20025	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ICI43_RS20030	COG1181	Belongs to the D-alanine--D-alanine ligase family
ICI43_RS20045	COG0772	Belongs to the SEDS family
ICI43_RS20050	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ICI43_RS20060	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ICI43_RS20065	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ICI43_RS20070	COG0768	penicillin binding
ICI43_RS20075	COG3116	cell division
ICI43_RS20080	COG0275	rRNA processing
ICI43_RS20090	COG1609	Transcriptional regulator
ICI43_RS20100	COG0440	acetolactate synthase activity
ICI43_RS20105	COG0028	Belongs to the TPP enzyme family
ICI43_RS20115	COG0583	DNA-binding transcription factor activity
ICI43_RS20130	COG0473	3-isopropylmalate dehydrogenase activity
ICI43_RS20155	COG4143	(ABC) transporter
ICI43_RS20160	COG1178	ABC-type Fe3 transport system permease component
ICI43_RS20165	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ICI43_RS20170	COG0586	Pfam SNARE associated Golgi protein
ICI43_RS20190	COG4977	sequence-specific DNA binding
ICI43_RS20195	COG1069	ribulokinase activity
ICI43_RS20200	COG2160	L-arabinose isomerase activity
ICI43_RS20205	COG0235	Class ii aldolase
ICI43_RS20210	COG0417	DNA replication proofreading
ICI43_RS20220	COG0564	pseudouridine synthase activity
ICI43_RS20225	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ICI43_RS20235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ICI43_RS20240	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ICI43_RS20270	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ICI43_RS20275	COG0475	glutathione-regulated potassium exporter activity
ICI43_RS20275	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ICI43_RS20285	COG2271	Major facilitator Superfamily
ICI43_RS20290	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ICI43_RS20295	COG0644	oxidoreductase
ICI43_RS20345	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ICI43_RS20350	COG0505	Belongs to the CarA family
ICI43_RS20375	COG1047	Peptidyl-prolyl cis-trans
ICI43_RS20390	COG0196	riboflavin kinase activity
ICI43_RS20405	COG0583	DNA-binding transcription factor activity
ICI43_RS20420	COG3119	arylsulfatase activity
ICI43_RS20450	COG4735	regulation of single-species biofilm formation
ICI43_RS20455	COG1584	GPR1 FUN34 yaaH family protein
ICI43_RS20460	COG0521	Mo-molybdopterin cofactor biosynthetic process
ICI43_RS20470	COG1115	amino acid carrier protein
ICI43_RS20485	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ICI43_RS20490	COG0083	homoserine kinase activity
ICI43_RS20495	COG0460	homoserine dehydrogenase
ICI43_RS20495	COG0527	aspartate kinase activity
ICI43_RS20505	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ICI43_RS20515	COG0745	RESPONSE REGULATOR receiver
ICI43_RS20520	COG4452	Inner membrane protein CreD
ICI43_RS20525	COG2205	protein histidine kinase activity
ICI43_RS20530	COG0745	RESPONSE REGULATOR receiver
ICI43_RS20535	COG3045	CreA protein
ICI43_RS20540	COG2207	Transcriptional regulator
ICI43_RS20540	COG3708	Transcriptional regulator
ICI43_RS20560	COG0741	lytic transglycosylase activity
ICI43_RS20565	COG0488	(ABC) transporter
ICI43_RS20570	COG3172	ATPase kinase involved in NAD metabolism
ICI43_RS20570	COG1056	cytidyltransferase-related domain
ICI43_RS20575	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ICI43_RS20580	COG0560	Phosphoserine phosphatase
ICI43_RS20585	COG3726	membrane protein affecting hemolysin expression
ICI43_RS20620	COG1328	CTP reductase activity
ICI43_RS20625	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ICI43_RS20630	COG0084	hydrolase, TatD family'
ICI43_RS20635	COG4667	esterase of the alpha-beta hydrolase superfamily
ICI43_RS20645	COG2823	Periplasmic or secreted lipoprotein
ICI43_RS20655	COG1011	Hydrolase
ICI43_RS20660	COG0456	acetyltransferase
ICI43_RS20665	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
ICI43_RS20695	COG4114	ferric iron reductase
ICI43_RS20700	COG2197	response regulator
ICI43_RS20705	COG2197	response regulator
ICI43_RS20710	COG2966	Psort location CytoplasmicMembrane, score
ICI43_RS20725	COG1484	DNA-dependent DNA replication
ICI43_RS20740	COG1063	alcohol dehydrogenase
ICI43_RS20745	COG1802	Transcriptional regulator
ICI43_RS20750	COG2271	Major facilitator Superfamily
ICI43_RS20755	COG0840	transmembrane signaling receptor activity
ICI43_RS20760	COG1966	Carbon starvation protein
ICI43_RS20765	COG2879	small protein
ICI43_RS20770	COG0523	cobalamin synthesis protein
ICI43_RS20785	COG1715	Restriction endonuclease
ICI43_RS20790	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ICI43_RS20795	COG0732	type I restriction modification DNA specificity domain
ICI43_RS20800	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ICI43_RS20810	COG5457	Domain of unknown function (DUF1127)
ICI43_RS20815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ICI43_RS20825	COG2814	Major facilitator Superfamily
ICI43_RS20830	COG2733	membrane
ICI43_RS20835	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
ICI43_RS20840	COG1924	4 iron, 4 sulfur cluster binding
ICI43_RS20855	COG0477	Major facilitator Superfamily
ICI43_RS20865	COG3366	ferrous iron transmembrane transporter activity
ICI43_RS20870	COG0700	Nucleoside recognition
ICI43_RS20875	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ICI43_RS20880	COG0583	DNA-binding transcription factor activity
ICI43_RS20900	COG2186	Transcriptional regulator
ICI43_RS20905	COG0246	Mannitol dehydrogenase
ICI43_RS20915	COG2610	gluconate transmembrane transporter activity
ICI43_RS20920	COG3539	Fimbrial protein
ICI43_RS20925	COG3539	Fimbrial protein
ICI43_RS20930	COG3539	Fimbrial protein
ICI43_RS20935	COG3188	usher protein
ICI43_RS20940	COG3121	Chaperone
ICI43_RS20945	COG3539	Fimbrial protein
ICI43_RS20955	COG4974	Belongs to the 'phage' integrase family
ICI43_RS20980	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ICI43_RS20985	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ICI43_RS21015	COG3153	acetyltransferase
ICI43_RS21020	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ICI43_RS21035	COG1363	Peptidase, m42
ICI43_RS21040	COG3414	Phosphotransferase system galactitol-specific IIB component
ICI43_RS21045	COG3775	system Galactitol-specific IIC component
ICI43_RS21050	COG0434	BtpA family
ICI43_RS21055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICI43_RS21060	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ICI43_RS21065	COG1349	DNA-binding transcription factor activity
ICI43_RS21070	COG1414	Transcriptional regulator
ICI43_RS21075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ICI43_RS21080	COG0129	dihydroxy-acid dehydratase activity
ICI43_RS21085	COG2610	gluconate transmembrane transporter activity
ICI43_RS21090	COG2390	Transcriptional regulator
ICI43_RS21115	COG1215	transferase activity, transferring glycosyl groups
ICI43_RS21190	COG2003	Belongs to the UPF0758 family
ICI43_RS21210	COG3468	outer membrane autotransporter barrel domain protein
ICI43_RS21260	COG3436	PFAM IS66 Orf2 family protein
ICI43_RS21265	COG4372	Transposase
ICI43_RS21285	COG1595	DNA-templated transcription, initiation
ICI43_RS21290	COG3712	iron ion homeostasis
ICI43_RS21295	COG4772	TonB-dependent receptor
ICI43_RS21300	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ICI43_RS21305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICI43_RS21310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICI43_RS21315	COG1120	ATPase activity
ICI43_RS21320	COG2085	NADP oxidoreductase coenzyme F420-dependent
ICI43_RS21330	COG2826	transposase and inactivated derivatives, IS30 family
ICI43_RS21390	COG1064	alcohol dehydrogenase
ICI43_RS21395	COG0433	COG0433 Predicted ATPase
ICI43_RS21400	COG0795	lipopolysaccharide-transporting ATPase activity
ICI43_RS21405	COG0795	lipopolysaccharide-transporting ATPase activity
ICI43_RS21415	COG2927	DNA polymerase III (CHI subunit)
ICI43_RS21420	COG0525	valine-tRNA ligase activity
ICI43_RS21430	COG0456	acetyltransferase
ICI43_RS21435	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ICI43_RS21440	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ICI43_RS21445	COG2731	YhcH YjgK YiaL family protein
ICI43_RS21455	COG0549	Belongs to the carbamate kinase family
ICI43_RS21460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ICI43_RS21465	COG1288	antiporter activity
ICI43_RS21470	COG1438	arginine binding
ICI43_RS21490	COG0251	oxidation-reduction process
ICI43_RS21495	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ICI43_RS21505	COG1609	Transcriptional regulator
ICI43_RS21510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ICI43_RS21510	COG1263	PTS System
ICI43_RS21515	COG0366	Alpha amylase catalytic
ICI43_RS21520	COG1328	CTP reductase activity
ICI43_RS21525	COG0602	queuosine metabolic process
ICI43_RS21530	COG3783	Cytochrome b(562)
ICI43_RS21535	COG0312	modulator of DNA gyrase
ICI43_RS21540	COG3028	Belongs to the UPF0307 family
ICI43_RS21545	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ICI43_RS21555	COG1172	Belongs to the binding-protein-dependent transport system permease family
ICI43_RS21560	COG1172	Belongs to the binding-protein-dependent transport system permease family
ICI43_RS21565	COG1129	ABC transporter
ICI43_RS21570	COG1879	ABC-type sugar transport system periplasmic component
ICI43_RS21575	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ICI43_RS21580	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ICI43_RS21585	COG2105	PFAM AIG2 family protein
ICI43_RS21590	COG2911	Protein conserved in bacteria
ICI43_RS21595	COG0729	surface antigen
ICI43_RS21600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ICI43_RS21605	COG1253	flavin adenine dinucleotide binding
ICI43_RS21615	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ICI43_RS21620	COG1218	3'(2'),5'-bisphosphate nucleotidase
ICI43_RS21625	COG0737	Belongs to the 5'-nucleotidase family
ICI43_RS21630	COG1733	regulation of RNA biosynthetic process
ICI43_RS21635	COG0702	epimerase
ICI43_RS21640	COG0697	spore germination
ICI43_RS21650	COG1113	amino acid transport
ICI43_RS21655	COG0545	Peptidyl-prolyl cis-trans isomerase
ICI43_RS21660	COG3061	Opacity-associated protein A
ICI43_RS21665	COG1309	transcriptional regulator
ICI43_RS21680	COG1024	Enoyl-CoA hydratase
ICI43_RS21685	COG4670	ketone body catabolic process
ICI43_RS21690	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ICI43_RS21695	COG2271	Major facilitator Superfamily
ICI43_RS21715	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ICI43_RS21735	COG0235	Class ii aldolase
ICI43_RS21750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICI43_RS21760	COG3037	sugar-specific permease SgaT UlaA
ICI43_RS21775	COG1073	alpha beta
ICI43_RS21780	COG3650	response to hydrogen peroxide
ICI43_RS21790	COG1960	acyl-CoA dehydrogenase activity
ICI43_RS21795	COG0754	glutathionylspermidine amidase activity
ICI43_RS21800	COG5463	Belongs to the UPF0441 family
ICI43_RS21805	COG3766	membrane
ICI43_RS21815	COG1842	Phage shock protein A
ICI43_RS21820	COG3789	protein conserved in bacteria
ICI43_RS21825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICI43_RS21830	COG0557	exoribonuclease II activity
ICI43_RS21845	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ICI43_RS21850	COG0330	HflC and HflK could
ICI43_RS21855	COG0330	HflC and HflK could
ICI43_RS21860	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ICI43_RS21875	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ICI43_RS21880	COG0860	N-Acetylmuramoyl-L-alanine amidase
ICI43_RS21885	COG0802	atpase or kinase
ICI43_RS21890	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ICI43_RS21890	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ICI43_RS21895	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ICI43_RS21935	COG1511	domain protein
ICI43_RS21935	COG3264	Mechanosensitive ion channel
ICI43_RS21940	COG0531	amino acid
ICI43_RS21950	COG1053	succinate dehydrogenase
ICI43_RS21955	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ICI43_RS21970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ICI43_RS21975	COG3040	lipid binding
ICI43_RS21980	COG2076	Multidrug Resistance protein
ICI43_RS21985	COG5510	response to toxic substance
ICI43_RS21990	COG5510	response to toxic substance
ICI43_RS22000	COG1509	lysine 2,3-aminomutase activity
ICI43_RS22025	COG0531	amino acid
ICI43_RS22030	COG3030	protein affecting phage T7 exclusion by the F plasmid
ICI43_RS22035	COG1027	Aspartate ammonia-lyase
ICI43_RS22040	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ICI43_RS22050	COG4232	protein-disulfide reductase activity
ICI43_RS22055	COG1309	transcriptional regulator
ICI43_RS22065	COG3710	Transcriptional regulator
ICI43_RS22070	COG0531	amino acid
ICI43_RS22075	COG1982	Orn Lys Arg decarboxylase major
ICI43_RS22080	COG3104	oligopeptide transport
ICI43_RS22085	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ICI43_RS22100	COG2388	GCN5-related N-acetyl-transferase
ICI43_RS22105	COG3592	Divergent 4Fe-4S mono-cluster
ICI43_RS22110	COG3290	protein histidine kinase activity
ICI43_RS22115	COG4565	transcriptional regulatory protein
ICI43_RS22120	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ICI43_RS22125	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ICI43_RS22125	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ICI43_RS22135	COG1486	melibiose metabolic process
ICI43_RS22140	COG2169	Transcriptional regulator
ICI43_RS22145	COG1982	Orn Lys Arg decarboxylase major
ICI43_RS22150	COG2207	Transcriptional regulator
ICI43_RS22155	COG0531	amino acid
ICI43_RS22160	COG2194	sulfuric ester hydrolase activity
ICI43_RS22165	COG0745	RESPONSE REGULATOR receiver
ICI43_RS22170	COG0642	Histidine kinase
ICI43_RS22180	COG0477	Major facilitator Superfamily
ICI43_RS22195	COG2824	Alkylphosphonate utilization operon protein PhnA
ICI43_RS22200	COG2764	glyoxalase bleomycin resistance protein dioxygenase
ICI43_RS22205	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ICI43_RS22210	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ICI43_RS22215	COG3639	organic phosphonate transmembrane transporter activity
ICI43_RS22220	COG2188	Transcriptional regulator
ICI43_RS22225	COG3624	Phosphonate C-P lyase system protein PhnG
ICI43_RS22230	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ICI43_RS22235	COG3626	phosphonate metabolism
ICI43_RS22240	COG3627	carbon phosphorus lyase activity
ICI43_RS22245	COG4107	phosphonate C-P lyase system protein PhnK
ICI43_RS22250	COG4778	phosphonate C-P lyase system protein PhnL
ICI43_RS22255	COG3454	Phosphonate metabolism
ICI43_RS22265	COG0456	acetyltransferase
ICI43_RS22270	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ICI43_RS22280	COG0698	ribose 5-phosphate isomerase
ICI43_RS22285	COG1737	Transcriptional regulator
ICI43_RS22290	COG1879	ABC-type sugar transport system periplasmic component
ICI43_RS22295	COG1129	ABC transporter
ICI43_RS22300	COG1172	Belongs to the binding-protein-dependent transport system permease family
ICI43_RS22305	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ICI43_RS22310	COG1940	carbohydrate kinase activity
ICI43_RS22315	COG2015	COG2015, Alkyl sulfatase and related hydrolases
ICI43_RS22325	COG1566	PFAM secretion protein HlyD family protein
ICI43_RS22330	COG1289	transmembrane transporter activity
ICI43_RS22335	COG1538	Outer membrane efflux protein
ICI43_RS22350	COG0601	transmembrane transport
ICI43_RS22355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICI43_RS22360	COG0444	Belongs to the ABC transporter superfamily
ICI43_RS22365	COG4608	Belongs to the ABC transporter superfamily
ICI43_RS22370	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ICI43_RS22375	COG1301	dicarboxylic acid transport
ICI43_RS22380	COG4235	cytochrome complex assembly
ICI43_RS22385	COG3088	subunit of a heme lyase
ICI43_RS22390	COG1138	Cytochrome C-type biogenesis protein
ICI43_RS22395	COG3301	Polysulphide reductase, NrfD
ICI43_RS22400	COG0437	4 iron, 4 sulfur cluster binding
ICI43_RS22405	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ICI43_RS22415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ICI43_RS22420	COG3162	membrane
ICI43_RS22430	COG1346	cytolysis
ICI43_RS22435	COG1380	Effector of murein hydrolase LrgA
ICI43_RS22440	COG0583	DNA-binding transcription factor activity
ICI43_RS22445	COG0025	NhaP-type Na H and K H
ICI43_RS22450	COG2252	PERMEase
ICI43_RS22455	COG0789	Transcriptional regulator
ICI43_RS22460	COG2207	Transcriptional regulator
ICI43_RS22465	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ICI43_RS22475	COG0629	single-stranded DNA binding
ICI43_RS22480	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ICI43_RS22485	COG2315	Protein conserved in bacteria
ICI43_RS22490	COG0432	Pfam Uncharacterised protein family UPF0047
ICI43_RS22495	COG3700	Belongs to the class B bacterial acid phosphatase family
ICI43_RS22505	COG2204	response regulator
ICI43_RS22510	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ICI43_RS22515	COG0471	metal ion transport
ICI43_RS22520	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ICI43_RS22525	COG0045	succinate-CoA ligase (ADP-forming) activity
ICI43_RS22530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ICI43_RS22540	COG0567	Dehydrogenase, E1 component
ICI43_RS22545	COG1448	Aminotransferase
ICI43_RS22555	COG3201	nicotinamide mononucleotide transporter
ICI43_RS22560	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ICI43_RS22570	COG0305	Participates in initiation and elongation during chromosome replication
ICI43_RS22575	COG1609	Transcriptional regulator
ICI43_RS22585	COG1024	Enoyl-CoA hydratase
ICI43_RS22590	COG0477	Major facilitator Superfamily
ICI43_RS22595	COG1053	succinate dehydrogenase
ICI43_RS22600	COG0604	alcohol dehydrogenase
ICI43_RS22610	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICI43_RS22615	COG0735	belongs to the Fur family
ICI43_RS22620	COG3237	CsbD-like
ICI43_RS22625	COG0534	Mate efflux family protein
ICI43_RS22635	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ICI43_RS22665	COG3842	ATPase activity
ICI43_RS22670	COG2182	Extracellular solute-binding protein
ICI43_RS22675	COG1175	transmembrane transport
ICI43_RS22680	COG3833	ABC-type maltose transport systems, permease component
ICI43_RS22695	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ICI43_RS22720	COG0527	aspartate kinase activity
ICI43_RS22730	COG1187	pseudouridine synthase activity
ICI43_RS22775	COG1283	sodium-dependent phosphate transmembrane transporter activity
ICI43_RS22790	COG1410	methionine synthase
ICI43_RS22790	COG0646	methionine synthase
ICI43_RS22795	COG1414	Transcriptional regulator
ICI43_RS22805	COG2224	Isocitrate lyase
ICI43_RS22810	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ICI43_RS22820	COG0456	acetyltransferase
ICI43_RS22850	COG0138	bifunctional purine biosynthesis protein purh
ICI43_RS22855	COG0151	Belongs to the GarS family
ICI43_RS22860	COG2204	response regulator
ICI43_RS22865	COG4191	Histidine kinase
ICI43_RS22870	COG3678	ATP-independent chaperone mediated protein folding
ICI43_RS22885	COG3068	Protein conserved in bacteria
ICI43_RS22905	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
ICI43_RS22910	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ICI43_RS22915	COG0352	thiamine-phosphate diphosphorylase activity
ICI43_RS22920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ICI43_RS22925	COG2104	thiamine diphosphate biosynthetic process
ICI43_RS22930	COG2022	thiamine diphosphate biosynthetic process
ICI43_RS22935	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ICI43_RS22970	COG0250	Participates in transcription elongation, termination and antitermination
ICI43_RS22975	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ICI43_RS23010	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ICI43_RS23010	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ICI43_RS23015	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ICI43_RS23070	COG0477	Major facilitator Superfamily
ICI43_RS23075	COG1473	amidohydrolase
ICI43_RS23085	COG0583	DNA-binding transcription factor activity
ICI43_RS23090	COG2271	Major facilitator Superfamily
ICI43_RS23095	COG4948	Mandelate Racemase Muconate Lactonizing
ICI43_RS23105	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ICI43_RS23110	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ICI43_RS23125	COG2194	sulfuric ester hydrolase activity
ICI43_RS23130	COG2207	Transcriptional regulator
ICI43_RS23135	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ICI43_RS23140	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ICI43_RS23145	COG1882	Formate acetyltransferase
ICI43_RS23150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ICI43_RS23155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ICI43_RS23160	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICI43_RS23160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ICI43_RS23160	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ICI43_RS23165	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ICI43_RS23170	COG0371	Dehydrogenase
ICI43_RS23175	COG3738	Protein conserved in bacteria
ICI43_RS23180	COG0697	spore germination
ICI43_RS23190	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ICI43_RS23195	COG0737	Belongs to the 5'-nucleotidase family
ICI43_RS23205	COG0737	Belongs to the 5'-nucleotidase family
ICI43_RS23210	COG0737	Belongs to the 5'-nucleotidase family
ICI43_RS23220	COG0527	aspartate kinase activity
ICI43_RS23220	COG0460	homoserine dehydrogenase
ICI43_RS23225	COG0626	cystathionine gamma-synthase activity
ICI43_RS23235	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
ICI43_RS23245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ICI43_RS23250	COG1609	Transcriptional regulator
ICI43_RS23255	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ICI43_RS23270	COG1575	Belongs to the MenA family. Type 1 subfamily
ICI43_RS23285	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ICI43_RS23290	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ICI43_RS23295	COG1494	fructose-1,6-bisphosphatase
ICI43_RS23305	COG0589	response to stress
ICI43_RS23310	COG3691	Protein conserved in bacteria
ICI43_RS23315	COG3152	Membrane
ICI43_RS23335	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ICI43_RS23350	COG3678	ATP-independent chaperone mediated protein folding
ICI43_RS23355	COG0745	RESPONSE REGULATOR receiver
ICI43_RS23360	COG2205	protein histidine kinase activity
ICI43_RS23365	COG2258	MOSC domain
ICI43_RS23375	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ICI43_RS23390	COG4977	sequence-specific DNA binding
ICI43_RS23400	COG4806	L-rhamnose isomerase
ICI43_RS23405	COG0235	Class ii aldolase
ICI43_RS23425	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ICI43_RS23435	COG0437	4 iron, 4 sulfur cluster binding
ICI43_RS23440	COG2864	formate dehydrogenase
ICI43_RS23465	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ICI43_RS23475	COG0456	acetyltransferase
ICI43_RS23490	COG1011	Hydrolase
ICI43_RS23500	COG0477	Major facilitator Superfamily
ICI43_RS23510	COG1063	alcohol dehydrogenase
ICI43_RS23515	COG3684	Belongs to the aldolase LacD family
ICI43_RS23520	COG2084	Dehydrogenase
ICI43_RS23525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICI43_RS23530	COG1349	DNA-binding transcription factor activity
ICI43_RS23535	COG2271	Major facilitator Superfamily
ICI43_RS23540	COG1082	Xylose isomerase domain protein TIM barrel
ICI43_RS23545	COG2188	Transcriptional regulator
ICI43_RS23550	COG1217	gtp-binding protein TYPA
ICI43_RS23555	COG0174	glutamine synthetase
ICI43_RS23560	COG3852	Histidine kinase
ICI43_RS23565	COG2204	response regulator
ICI43_RS23575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ICI43_RS23590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ICI43_RS23590	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ICI43_RS23595	COG0204	Acyl-transferase
ICI43_RS23600	COG5339	Protein conserved in bacteria
ICI43_RS23605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ICI43_RS23610	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ICI43_RS23615	COG3084	Protein conserved in bacteria
ICI43_RS23620	COG0746	molybdenum cofactor guanylyltransferase activity
ICI43_RS23625	COG1763	Mo-molybdopterin cofactor biosynthetic process
ICI43_RS23650	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ICI43_RS23655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ICI43_RS23660	COG1739	Uncharacterized protein family UPF0029
ICI43_RS23670	COG1024	Enoyl-CoA hydratase
ICI43_RS23670	COG1250	3-hydroxyacyl-CoA dehydrogenase
ICI43_RS23675	COG0183	Belongs to the thiolase family
ICI43_RS23680	COG0543	2 iron, 2 sulfur cluster binding
ICI43_RS23685	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ICI43_RS23700	COG0805	protein transport
ICI43_RS23710	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ICI43_RS23720	COG3165	ubiquinone biosynthetic process from chorismate
ICI43_RS23730	COG1322	Protein conserved in bacteria
ICI43_RS23735	COG1414	Transcriptional regulator
ICI43_RS23740	COG3734	2-keto-3-deoxy-galactonokinase
ICI43_RS23745	COG0800	Aldolase
ICI43_RS23765	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ICI43_RS23770	COG0412	Dienelactone hydrolase
ICI43_RS23775	COG1335	isochorismatase
ICI43_RS23785	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ICI43_RS23790	COG1304	FMN binding
ICI43_RS23795	COG0549	Belongs to the carbamate kinase family
ICI43_RS23805	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ICI43_RS23810	COG0583	DNA-binding transcription factor activity
ICI43_RS23815	COG1737	Transcriptional regulator
ICI43_RS23820	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ICI43_RS23825	COG1263	PTS System
ICI43_RS23825	COG2190	(PTS) system
ICI43_RS23825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ICI43_RS23835	COG3157	Type VI secretion system effector, Hcp
ICI43_RS23840	COG3157	Type VI secretion system effector, Hcp
ICI43_RS23850	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ICI43_RS23855	COG0583	DNA-binding transcription factor activity
ICI43_RS23860	COG0697	spore germination
ICI43_RS23865	COG0561	phosphatase activity
ICI43_RS23870	COG2267	carboxylic ester hydrolase activity
ICI43_RS23875	COG1280	lysine exporter protein (LysE YggA)
ICI43_RS23880	COG1280	lysine exporter protein (LysE YggA)
ICI43_RS23885	COG0514	ATP-dependent DNA helicase (RecQ)
ICI43_RS23890	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
ICI43_RS23895	COG2050	protein possibly involved in aromatic compounds catabolism
ICI43_RS23900	COG2962	Rard protein
ICI43_RS23915	COG0598	Magnesium transport protein CorA
ICI43_RS23920	COG3698	Phosphodiester glycosidase
ICI43_RS23925	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
ICI43_RS23930	COG0210	DNA helicase
ICI43_RS23935	COG1011	Hydrolase
ICI43_RS23945	COG3159	Protein conserved in bacteria
ICI43_RS23950	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ICI43_RS23955	COG5567	small periplasmic lipoprotein
ICI43_RS23970	COG1965	Belongs to the frataxin family
ICI43_RS23975	COG3072	Adenylate cyclase
ICI43_RS23980	COG0181	hydroxymethylbilane synthase activity
ICI43_RS23985	COG1587	Uroporphyrinogen-III synthase
ICI43_RS23990	COG2959	enzyme of heme biosynthesis
ICI43_RS23995	COG3071	HemY protein
ICI43_RS24000	COG3119	arylsulfatase activity
ICI43_RS24005	COG0641	radical SAM
ICI43_RS24030	COG1113	amino acid transport
ICI43_RS24045	COG1819	glycosyl
ICI43_RS24050	COG2244	polysaccharide biosynthetic process
ICI43_RS24055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ICI43_RS24060	COG0456	acetyltransferase
ICI43_RS24065	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ICI43_RS24070	COG1088	dTDP-glucose 4,6-dehydratase activity
ICI43_RS24075	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ICI43_RS24080	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ICI43_RS24085	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ICI43_RS24090	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ICI43_RS24095	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ICI43_RS24105	COG3118	belongs to the thioredoxin family
ICI43_RS24120	COG0210	DNA helicase
ICI43_RS24125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ICI43_RS24135	COG0583	DNA-binding transcription factor activity
ICI43_RS24140	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ICI43_RS24145	COG0129	dihydroxy-acid dehydratase activity
ICI43_RS24150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ICI43_RS24155	COG3978	acetolactate synthase activity
ICI43_RS24175	COG0606	chelatase, subunit chli
ICI43_RS24180	COG3085	chromosome segregation
ICI43_RS24220	COG2186	Transcriptional regulator
ICI43_RS24225	COG0477	Major facilitator Superfamily
ICI43_RS24230	COG1609	Transcriptional regulator
ICI43_RS24235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICI43_RS24240	COG1879	ABC-type sugar transport system periplasmic component
ICI43_RS24245	COG1172	Belongs to the binding-protein-dependent transport system permease family
ICI43_RS24250	COG1129	ABC transporter
ICI43_RS24255	COG1869	D-ribose catabolic process
ICI43_RS24265	COG0714	Associated with various cellular activities
ICI43_RS24280	COG1522	sequence-specific DNA binding
ICI43_RS24285	COG0716	FMN binding
ICI43_RS24300	COG3312	ion transport
ICI43_RS24345	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ICI43_RS24350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ICI43_RS24355	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ICI43_RS24360	COG0573	inorganic phosphate transmembrane transporter activity
ICI43_RS24365	COG0581	inorganic phosphate transmembrane transporter activity
ICI43_RS24370	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ICI43_RS24375	COG0704	Plays a role in the regulation of phosphate uptake
ICI43_RS24380	COG3711	transcriptional antiterminator
ICI43_RS24385	COG1263	PTS System
ICI43_RS24385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ICI43_RS24385	COG2190	(PTS) system
ICI43_RS24390	COG2723	6-phospho-beta-galactosidase activity
ICI43_RS24395	COG4580	involved in the transport of maltose and maltodextrins
ICI43_RS24400	COG2382	esterase
ICI43_RS24405	COG0363	glucosamine-6-phosphate deaminase activity
ICI43_RS24415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ICI43_RS24420	COG2252	PERMEase
ICI43_RS24425	COG0431	NADPH-dependent FMN reductase
ICI43_RS24430	COG2091	lysine biosynthetic process via aminoadipic acid
ICI43_RS24435	COG0583	DNA-binding transcription factor activity
ICI43_RS24445	COG0814	amino acid
ICI43_RS24450	COG3033	Beta-eliminating lyase
ICI43_RS24595	COG1475	DNA binding
ICI43_RS24600	COG1475	DNA binding
ICI43_RS24610	COG1475	DNA binding
ICI43_RS24635	COG0740	serine-type endopeptidase activity
ICI43_RS24740	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ICI43_RS24760	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
ICI43_RS24775	COG1476	TRANSCRIPTIONal
ICI43_RS24825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ICI43_RS24840	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ICI43_RS24895	COG2026	Addiction module toxin, RelE StbE family
ICI43_RS24935	COG1192	Involved in chromosome partitioning