locus_tag old_locus_tag gene Name start end strand product note type ID NCBI HW43_RS00005 HW43_00010 rpmH rpmH 595 735 + 50S ribosomal protein L34 in Escherichia coli transcription of this gene is enhanced by polyamines gene gene0 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00005 HW43_RS00010 HW43_00015 rnpA rnpA 752 1111 + ribonuclease P protein component protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus%3B this enzyme also cleaves other RNA substrates gene gene1 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00010 HW43_RS00015 HW43_24170 HW43_RS00015 1075 1332 + membrane protein insertion efficiency factor YidD gene gene2 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00015 HW43_RS00020 HW43_00020 HW43_RS00020 1335 2981 + protein translocase component YidC functions to insert inner membrane proteins into the IM in Escherichia coli%3B interacts with transmembrane segments%3B functions in both Sec-dependent and -independent membrane insertion%3B similar to Oxa1p in mitochondria gene gene3 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00020 HW43_RS00025 HW43_00025 trmE trmE 3087 4451 + tRNA modification GTPase MnmE in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine%2C which is found in the wobble position of some tRNAs and affects ribosomal frameshifting%3B shows potassium-dependent dimerization and GTP hydrolysis%3B also involved in regulation of glutamate-dependent acid resistance and activation of gadE gene gene4 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00025 HW43_RS00030 HW43_24235 HW43_RS00030 4694 4768 + tryptophanase leader peptide gene gene5 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00030 HW43_RS00035 HW43_00030 tnaA tnaA 4989 6404 + tryptophanase tryptophan indole-lyase%3B catalyzes the formation of indole and pyruvate from tryptophan%3B also has xysteine desulfhydrase activity gene gene6 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00035 HW43_RS00040 HW43_00035 HW43_RS00040 6495 7742 + tryptophan permease tryptophan transporter of high affinity gene gene7 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00040 HW43_RS00045 HW43_00040 HW43_RS00045 7875 9050 + multidrug resistance protein MdtL Confers resistance to chloramphenicol gene gene8 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00045 HW43_RS00050 HW43_00045 HW43_RS00050 9025 9984 + transcriptional regulator Involved in anaerobic NO protection gene gene9 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00050 HW43_RS00055 HW43_00050 HW43_RS00055 10141 10890 + hypothetical protein gene gene10 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00055 HW43_RS00060 HW43_00055 HW43_RS00060 10912 11478 + chromate reductase gene gene11 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00060 HW43_RS00065 HW43_00060 HW43_RS00065 11532 12869 - adenine permease involved in the transport or adenine gene gene12 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00065 HW43_RS00070 HW43_00065 HW43_RS00070 13036 13701 + 6-phosphogluconate phosphatase YieH%3B catalyzes the dephosphorylation of phosphoenolpyruvate%2C AMP and p-nitrophenyl phosphate%3B purine and pyrimidine nucleotides are secondary substrates%3B member of the haloacid dehalogenase-like hydrolases superfamily gene gene13 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00070 HW43_RS00075 HW43_00070 HW43_RS00075 13768 14241 + hypothetical protein might be involved in hypersensitivity to nitrofurzone gene gene14 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00075 HW43_RS00080 HW43_00075 HW43_RS00080 14290 14877 + hypothetical protein gene gene15 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00080 HW43_RS00085 HW43_00080 HW43_RS00085 14939 15661 - 6-phosphogluconolactonase gene gene16 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00085 HW43_RS00090 HW43_00085 HW43_RS00090 15676 16845 - hypothetical protein gene gene17 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00090 HW43_RS00095 HW43_00090 HW43_RS00095 16872 18488 - porin gene gene18 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00095 HW43_RS00100 HW43_00095 HW43_RS00100 18574 19968 - 6-phospho-beta-glucosidase gene gene19 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00100 HW43_RS00105 HW43_00100 HW43_RS00105 19987 21864 - PTS beta-glucoside transporter subunit IIABC phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene20 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00105 HW43_RS00110 HW43_00105 HW43_RS00110 21997 22833 - cryptic beta-glucoside bgl operon antiterminator positive regulator of the beta-glucoside operon%3B transcriptional antiterminator gene gene21 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00110 HW43_RS00115 HW43_00110 HW43_RS00115 23119 23844 - phosphate-specific transport system accessory protein PhoU regulates several genes involved in high affinity phosphate uptake%3B under conditions of high phosphate concentrations downregulates the PHO regulon gene gene22 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00115 HW43_RS00120 HW43_00115 HW43_RS00120 23859 24632 - phosphate import ATP-binding protein PstB gene gene23 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00120 HW43_RS00125 HW43_00120 pstA pstA 24723 25613 - phosphate transporter permease subunit PtsA Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions gene gene24 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00125 HW43_RS00130 HW43_00125 pstC pstC 25613 26572 - phosphate ABC transporter permease part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions gene gene25 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00130 HW43_RS00135 HW43_00130 HW43_RS00135 26659 27699 - phosphate-binding protein gene gene26 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00135 HW43_RS00140 HW43_00135 HW43_RS00140 27947 29020 - fimbrial protein gene gene27 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00140 HW43_RS00145 HW43_00140 HW43_RS00145 29031 31553 - fimbrial protein gene gene28 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00145 HW43_RS00150 HW43_00145 lfpB lfpB 31578 32309 - fimbrial chaperone protein gene gene29 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00150 HW43_RS00155 HW43_00150 lpfA lpfA 32357 32929 - fimbrial protein gene gene30 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00155 HW43_RS00160 HW43_00155 HW43_RS00160 33231 35060 - glutamine--fructose-6-phosphate aminotransferase [isomerizing] Catalyzes the first step in hexosamine metabolism%2C converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source gene gene31 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00160 HW43_RS00165 HW43_00160 glmU glmU 35222 36592 - bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase forms a homotrimer%3B catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc%3B function in cell wall synthesis gene gene32 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00165 HW43_RS00170 HW43_00170 atpC atpC 36943 37362 - ATP synthase epsilon chain part of catalytic core of ATP synthase%3B alpha(3)beta(3)gamma(1)delta(1)epsilon(1)%3B involved in producing ATP from ADP in the presence of the proton motive force across the membrane gene gene33 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00170 HW43_RS00175 HW43_00175 HW43_RS00175 37383 38765 - ATP synthase subunit beta gene gene34 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00175 HW43_RS00180 HW43_00180 HW43_RS00180 38792 39655 - ATP synthase subunit gamma Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit gene gene35 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00180 HW43_RS00185 HW43_00185 HW43_RS00185 39706 41247 - ATP synthase subunit alpha produces ATP from ADP in the presence of a proton gradient across the membrane%3B the alpha chain is a catalytic subunit gene gene36 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00185 HW43_RS00190 HW43_00190 HW43_RS00190 41260 41793 - ATP synthase subunit delta Produces ATP from ADP in the presence of a proton gradient across the membrane%3B the delta subunit is part of the catalytic core of the ATP synthase complex gene gene37 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00190 HW43_RS00195 HW43_00195 HW43_RS00195 41808 42278 - ATP synthase subunit b Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. gene gene38 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00195 HW43_RS00200 HW43_00200 HW43_RS00200 42340 42579 - ATP synthase subunit c Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 gene gene39 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00200 HW43_RS00205 HW43_00205 HW43_RS00205 42626 43441 - ATP synthase subunit a Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 gene gene40 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00205 HW43_RS00210 HW43_00210 HW43_RS00210 43450 43830 - ATP synthase I Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation gene gene41 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00210 HW43_RS00215 HW43_00215 gidB gidB 44447 45070 - ribosomal RNA small subunit methyltransferase G glucose-inhibited division protein B%3B SAM-dependent methyltransferase%3B methylates the N7 position of guanosine in position 527 of 16S rRNA gene gene42 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00215 HW43_RS00220 HW43_00220 gidA gidA 45134 47023 - tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GidA%3B glucose-inhibited cell division protein A%3B involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs gene gene43 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00220 HW43_RS00225 HW43_00225 HW43_RS00225 47401 47844 - FMN-binding protein MioC An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group gene gene44 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00225 HW43_RS00230 HW43_00230 HW43_RS00230 47934 48392 - AsnC family transcriptional regulator transcriptional repressor of asnA which codes for aspartate-ammonia ligase gene gene45 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00230 HW43_RS00235 HW43_00235 HW43_RS00235 48544 49536 + aspartate--ammonia ligase catalyzes the formation of asparagine from aspartate and ammonia gene gene46 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00235 HW43_RS00240 HW43_00240 HW43_RS00240 49541 50992 - protein ViaA contains a von Willibrand factor type A domain%3B stimulates the ATPase activity of RavA gene gene47 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00240 HW43_RS00245 HW43_00245 HW43_RS00245 50986 52482 - ATPase RavA interacts with LdcI%2C lysine decarboxylase%3B may be active in late log/ early stationary phase gene gene48 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00245 HW43_RS00250 HW43_00250 trkD trkD 52705 54573 + low affinity potassium transport system protein kup Responsible for the low-affinity transport of potassium into the cell%3B involved in potassium ion uptake under hyper-osmotic stress at a low pH gene gene49 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00250 HW43_RS00255 HW43_00255 HW43_RS00255 54740 55159 + D-ribose pyranase cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose%3B RbsD is required for efficient ribose utilization in E. coli%3B rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source gene gene50 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00255 HW43_RS00260 HW43_00260 HW43_RS00260 55167 56672 + D-ribose transporter ATP-binding protein gene gene51 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00260 HW43_RS00265 HW43_00265 rbsC rbsC 56677 57642 + ribose ABC transporter permease functions to transport ribose at high affinity%3B forms a complex with RbsA2C2B gene gene52 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00265 HW43_RS00270 HW43_00270 HW43_RS00270 57667 58557 + D-ribose transporter subunit RbsB periplasmic substrate-binding component of the ATP-dependent ribose transport system gene gene53 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00270 HW43_RS00275 HW43_00275 HW43_RS00275 58683 59612 + ribokinase catalyzes the formation of D-ribose 5-phosphate from ribose gene gene54 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00275 HW43_RS00280 HW43_00280 HW43_RS00280 59625 60608 + LacI family transcriptional regulator binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis%3B is involved in regulation of purB%2C purC%2C purEK%2C purHD%2C purL%2C purMN and guaBA expression%3B binds hypoxanthine and guanine as inducers gene gene55 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00280 HW43_RS00285 HW43_00285 HW43_RS00285 60574 62001 - transporter gene gene56 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00285 HW43_RS00290 HW43_00290 HW43_RS00290 62024 62716 - GntR family transcriptional regulator gene gene57 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00290 HW43_RS00295 HW43_00295 HW43_RS00295 63193 64748 + 16S ribosomal RNA rRNA gene58 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00295 HW43_RS00300 HW43_00300 HW43_RS00300 64822 64897 + tRNA-Glu tRNA gene59 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00300 HW43_RS00305 HW43_00305 HW43_RS00305 65082 68006 + 23S ribosomal RNA rRNA gene60 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00305 HW43_RS00310 HW43_00310 HW43_RS00310 68089 68204 + 5S ribosomal RNA rRNA gene61 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00310 HW43_RS00315 HW43_00315 HW43_RS00315 68259 68335 + tRNA-Asp tRNA gene62 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00315 HW43_RS00320 HW43_00320 HW43_RS00320 68344 68419 + tRNA-Trp tRNA gene63 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00320 HW43_RS00325 HW43_00325 HW43_RS00325 68515 69354 - transcriptional regulator Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon gene gene64 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00325 HW43_RS00330 HW43_00330 HW43_RS00330 69473 69811 + hypothetical protein gene gene65 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00330 HW43_RS00335 HW43_00335 HW43_RS00335 69836 71356 - ATP-dependent protease among the AAA+ ATPases%2C the YifB protease family belongs to the Helix 2 insert clade%3B unknown function gene gene66 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00335 HW43_RS00340 HW43_24260 HW43_RS00340 71709 71807 + IlvGMEDA operon leader peptide gene gene67 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00340 HW43_RS00345 HW43_00345 HW43_RS00345 71947 73593 + acetolactate synthase catalyzes the formation of 2-acetolactate from pyruvate%3B also known as acetolactate synthase large subunit gene gene68 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00345 HW43_RS00350 HW43_00350 ilvM ilvM 73590 73853 + acetolactate synthase isozyme 2 small subunit gene gene69 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00350 HW43_RS00355 HW43_00355 HW43_RS00355 73873 74802 + branched-chain-amino-acid aminotransferase gene gene70 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00355 HW43_RS00360 HW43_00360 HW43_RS00360 74867 76717 + dihydroxy-acid dehydratase catalyzes the dehydration of 2%2C3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis gene gene71 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00360 HW43_RS00365 HW43_00365 HW43_RS00365 76720 78264 + threonine dehydratase threonine deaminase%3B threonine dehydratase%3B in Escherichia coli%2C IlvA is part of the isoleucine biosynthetic pathway gene gene72 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00365 HW43_RS00370 HW43_00370 HW43_RS00370 78316 79209 - transcriptional regulator participates in controlling several genes involved in isoleucine and valine biosynthesis%3B activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate gene gene73 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00370 HW43_RS00375 HW43_00375 HW43_RS00375 79359 80834 + ketol-acid reductoisomerase catalyzes the formation of (R)-2%2C3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis gene gene74 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00375 HW43_RS00380 HW43_00380 HW43_RS00380 80921 81202 - peptidyl-prolyl cis-trans isomerase rotamase C%3B accelerates isomerization of the peptidyl prolyl bond gene gene75 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00380 HW43_RS00385 HW43_00385 HW43_RS00385 81401 81850 - hypothetical protein gene gene76 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00385 HW43_RS00390 HW43_00390 HW43_RS00390 82067 84088 + ATP-dependent DNA helicase Rep single-stranded DNA-dependent ATPase%3B initiates unwinding at a nick in the DNA%3B involved in DNA replication gene gene77 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00390 HW43_RS00395 HW43_00395 HW43_RS00395 84135 85619 - guanosine-5'-triphosphate%2C3'-diphosphate pyrophosphatase catalyzes the conversion of guanosine 5'-triphosphate%2C3'-diphosphate (pppGpp) to guanosine 5'-diphosphate%2C3'-diphosphate (ppGpp)%3B pppGpp and ppGpp control the stringent response during amino acid starvation gene gene78 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00395 HW43_RS00400 HW43_00400 HW43_RS00400 85753 87018 - ATP-dependent RNA helicase RhlB enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome%2C a multi-enzyme complex important in RNA processing and messenger RNA degradation gene gene79 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00400 HW43_RS00405 HW43_00405 trxA trxA 87149 87478 + thioredoxin gene gene80 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00405 HW43_RS00410 HW43_24340 HW43_RS00410 87619 87720 + rho operon leader peptide gene gene81 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00410 HW43_RS00415 HW43_00410 rho rho 87805 89064 + transcription termination factor Rho An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes gene gene82 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00415 HW43_RS00420 HW43_00415 HW43_RS00420 89074 89292 + hypothetical protein gene gene83 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00420 HW43_RS00425 HW43_00420 HW43_RS00425 89304 90407 + undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase catalyzes the formation of alpha-N-acetylglucosaminyl-pyrophosphoryl-undecaprenyl from alpha-N-acetylglucosaminyl 1-phosphate and the lipid carrier undecaprenyl phosphate gene gene84 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00425 HW43_RS00430 HW43_00425 HW43_RS00430 90419 91465 + LPS biosynthesis protein Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein gene gene85 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00430 HW43_RS00435 HW43_00430 HW43_RS00435 91521 92651 + UDP-N-acetylglucosamine 2-epimerase gene gene86 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00435 HW43_RS00440 HW43_00435 wecC wecC 92648 93910 + UDP-N-acetyl-D-mannosamine dehydrogenase catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid gene gene87 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00440 HW43_RS00445 HW43_00440 HW43_RS00445 93910 94977 + dTDP-glucose 4%2C6-dehydratase gene gene88 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00445 HW43_RS00450 HW43_00445 HW43_RS00450 94996 95877 + glucose-1-phosphate thymidylyltransferase 2 gene gene89 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00450 HW43_RS00455 HW43_00450 HW43_RS00455 95855 96529 + TDP-fucosamine acetyltransferase gene gene90 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00455 HW43_RS00460 HW43_00455 HW43_RS00460 96534 97664 + TDP-4-oxo-6-deoxy-D-glucose aminotransferase catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis gene gene91 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00460 HW43_RS00465 HW43_00460 HW43_RS00465 97666 98916 + translocase involved in the movement of lipid III across the membrane gene gene92 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00465 HW43_RS00470 HW43_00465 HW43_RS00470 98913 99992 + 4-alpha-L-fucosyltransferase catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis gene gene93 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00470 HW43_RS00475 HW43_00470 HW43_RS00475 99989 101341 + polymerase enterobacterial common antigen polymerase gene gene94 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00475 HW43_RS00480 HW43_00475 HW43_RS00480 101344 102084 + UDP-N-acetyl-D-mannosaminuronic acid transferase gene gene95 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00480 HW43_RS00485 HW43_00480 HW43_RS00485 102275 103660 + transporter involved in the transport across the cytoplasmic membrane of D-alanine%2C D-serine and glycine gene gene96 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00485 HW43_RS00490 HW43_00485 HW43_RS00490 103763 103839 + tRNA-Arg tRNA gene97 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00490 HW43_RS00495 HW43_00490 HW43_RS00495 103898 103973 + tRNA-His tRNA gene98 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00495 HW43_RS00500 HW43_00495 HW43_RS00500 103994 104080 + tRNA-Leu tRNA gene99 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00500 HW43_RS00505 HW43_00500 HW43_RS00505 104123 104199 + tRNA-Pro tRNA gene100 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00505 HW43_RS00510 HW43_00505 HW43_RS00510 104346 105581 + anaerobic sulfatase maturase AslB gene gene101 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00510 HW43_RS00515 HW43_00510 HW43_RS00515 105665 105826 - arylsulfatase gene gene102 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00515 HW43_RS00520 HW43_00515 HW43_RS00520 106505 107701 - heme biosynthesis protein HemY gene gene103 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00520 HW43_RS00525 HW43_00520 HW43_RS00525 107704 108945 - heme biosynthesis operon protein HemX gene gene104 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00525 HW43_RS00530 HW43_00525 hemD hemD 108967 109707 - uroporphyrinogen III methyltransferase catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane%3B functions in tetrapyrrole and heme biosynthesis gene gene105 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00530 HW43_RS00535 HW43_00530 hemC hemC 109704 110645 - porphobilinogen deaminase transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis gene gene106 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00535 HW43_RS00540 HW43_00535 cyaA cyaA 111032 113578 + adenylate cyclase catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP gene gene107 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00540 HW43_RS00545 HW43_00540 cyaY cyaY 113618 113938 - protein CyaY iron-dependent inhibitor of iron-sulfur cluster formation%3B iron-binding and oxidizing protein%3B defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease%3B based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly gene gene108 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00545 HW43_RS00550 HW43_00545 HW43_RS00550 113986 115311 - hypothetical protein gene gene109 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00550 HW43_RS00555 HW43_00550 HW43_RS00555 115308 116786 - hypothetical protein gene gene110 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00555 HW43_RS00560 HW43_00555 HW43_RS00560 117154 117708 - hypothetical protein gene gene111 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00560 HW43_RS00565 HW43_00560 HW43_RS00565 118058 118261 + lipoprotein gene gene112 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00565 HW43_RS00570 HW43_00565 dapF dapF 118298 119122 + diaminopimelate epimerase involved in lysine biosynthesis%3B DAP epimerase%3B produces DL-diaminopimelate from LL-diaminopimelate gene gene113 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00570 HW43_RS00575 HW43_00570 HW43_RS00575 119119 119826 + DUF484 domain-containing protein gene gene114 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00575 HW43_RS00580 HW43_00575 xerC xerC 119823 120719 + tyrosine recombinase XerC site-specific tyrosine recombinase which cuts and rejoins DNA molecules%3B binds cooperatively to specific DNA consensus sites%3B forms a heterotetrameric complex with XerC%3B XerCD exhibit similar sequences%3B essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation%3B cell division protein FtsK may regulate the XerCD complex%3B enzyme from Streptococcus group has unusual active site motifs gene gene115 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00580 HW43_RS00585 HW43_00580 HW43_RS00585 120719 121435 + flavin mononucleotide phosphatase YigB YigB%3B member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein%3B unknown function gene gene116 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00585 HW43_RS00590 HW43_00585 uvrD uvrD 121519 123681 + DNA helicase II unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present%3B involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. gene gene117 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00590 HW43_RS00595 HW43_00590 HW43_RS00595 123828 124592 - hypothetical protein gene gene118 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00595 HW43_RS00600 HW43_24345 HW43_RS00600 124605 124718 + hypothetical protein gene gene119 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00600 HW43_RS00605 HW43_00600 HW43_RS00605 124962 125912 + magnesium transporter CorA responsible for the influx of magnesium ions gene gene120 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00605 HW43_RS00610 HW43_00605 HW43_RS00610 125966 126445 - membrane protein gene gene121 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00610 HW43_RS00615 HW43_00610 HW43_RS00615 126442 127290 - hypothetical protein gene gene122 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00615 HW43_RS00620 HW43_00615 HW43_RS00620 127426 127623 + hypothetical protein gene gene123 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00620 HW43_RS00625 HW43_00620 HW43_RS00625 128247 128546 + membrane protein gene gene124 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00625 HW43_RS00630 HW43_00625 HW43_RS00630 128593 129480 - chloramphenicol resistance permease RarD gene gene125 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00630 HW43_RS00635 HW43_00630 HW43_RS00635 129532 129999 - hypothetical protein gene gene126 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00635 HW43_RS00640 HW43_00635 HW43_RS00640 130164 131033 + phospholipase A1 catalyzes the hydrolysis of phosphatidylcholine gene gene127 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00640 HW43_RS00645 HW43_00640 HW43_RS00645 131166 132995 + ATP-dependent DNA helicase RecQ functions in blocking illegitimate recombination%2C enhancing topoisomerase activity%2C initiating SOS signaling and clearing blocked replication forks%3B component of the RecF recombinational pathway gene gene128 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00645 HW43_RS00650 HW43_00645 HW43_RS00650 133059 133679 + threonine efflux protein gene gene129 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00650 HW43_RS00655 HW43_00650 rhtB rhtB 133741 134361 - homoserine/homoserine lactone efflux protein gene gene130 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00655 HW43_RS00660 HW43_00655 HW43_RS00660 134472 135494 + lysophospholipase L2 lecithinase B%3B catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine%3B can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates gene gene131 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00660 HW43_RS00665 HW43_00660 HW43_RS00665 135502 136302 + pyridoxal phosphate phosphatase YigL gene gene132 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00665 HW43_RS00670 HW43_00665 HW43_RS00670 136378 137277 + EamA-like transporter gene gene133 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00670 HW43_RS00675 HW43_00670 HW43_RS00675 137165 138118 - transcriptional regulator homocysteine-binding%3B positive regulator of metA%2C metE and metH gene gene134 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00675 HW43_RS00680 HW43_00675 HW43_RS00680 138236 140497 + 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene135 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00680 HW43_RS00685 HW43_00680 HW43_RS00685 140537 141352 - carboxymethylenebutenolidase gene gene136 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00685 HW43_RS00690 HW43_00685 HW43_RS00690 141614 142375 + uridine phosphorylase catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate%3B involved in the pyrimidine salvage pathway gene gene137 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00690 HW43_RS00695 HW43_00690 HW43_RS00695 142516 143943 + DNA recombination protein RmuC YigN%3B nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence%3B transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner gene gene138 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00695 HW43_RS00700 HW43_00695 ubiE ubiE 144038 144793 + ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone and menaquinone gene gene139 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00700 HW43_RS00705 HW43_00700 HW43_RS00705 144807 145412 + ubiquinone biosynthesis protein UbiJ gene gene140 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00705 HW43_RS00710 HW43_00705 ubiB ubiB 145409 147049 + hypothetical protein an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone%3B functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis%3B similar to eukaryotic proteins that exhibit kinase functions gene gene141 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00710 HW43_RS00715 HW43_00710 tatA tatA 147128 147397 + protein translocase TatA TatA%3B similar to TatE that is found in some proteobacteria%3B part of system that translocates proteins with a conserved twin arginine motif across the inner membrane%3B capable of translocating folded substrates typically those with bound cofactors%3B similar to a protein import system in thylakoid membranes gene gene142 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00715 HW43_RS00720 HW43_00715 HW43_RS00720 147401 147916 + Sec-independent protein translocase TatB mediates the export of protein precursors bearing twin-arginine signal peptides gene gene143 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00720 HW43_RS00725 HW43_00720 HW43_RS00725 147919 148695 + preprotein translocase subunit TatC with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane gene gene144 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00725 HW43_RS00730 HW43_00725 HW43_RS00730 148737 149519 + DNase TatD magnesium dependent%3B involved in quality control of mutated Tat exported substrates%3B not involved in the Sec-independent protein export system gene gene145 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00730 HW43_RS00735 HW43_00730 rfaH rfaH 149516 150004 - transcription antitermination protein RfaH gene gene146 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00735 HW43_RS00740 HW43_00735 HW43_RS00740 150171 151664 + 3-octaprenyl-4-hydroxybenzoate carboxy-lyase catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol gene gene147 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00740 HW43_RS00745 HW43_00740 fre fre 151710 152411 + NAD(P)H-flavin reductase NAD(P)H-flavin reductase%3B catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide%3B in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin gene gene148 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00745 HW43_RS00750 HW43_00745 fadA fadA 152603 153766 - 3-ketoacyl-CoA thiolase FadA%3B fatty acid oxidation complex component beta%3B functions in a heterotetramer with FadB%3B similar to FadI2J2 complex%3B functions in beta-oxidation of fatty acids gene gene149 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00750 HW43_RS00755 HW43_24350 fadB fadB 153776 155965 - multifunctional fatty acid oxidation complex subunit alpha includes enoyl-CoA hydratase%2C delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase%2C 3-hydroxyacyl-CoA dehydrogenase%2C and 3-hydroxybutyryl-CoA epimerase%3B catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA%3B also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities%3B forms a heterotetramer with FadA%3B similar to FadI2J2 complex%3B functions in beta-oxidation of fatty acids gene gene150 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00755 HW43_RS00760 HW43_00830 HW43_RS00760 156155 157486 + Xaa-Pro dipeptidase catalyzes the hydrolysis of dipeptides with a proline at the C-terminal%3B also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters gene gene151 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00760 HW43_RS00765 HW43_00835 HW43_RS00765 157486 158100 + hypothetical protein gene gene152 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00765 HW43_RS00770 HW43_00840 HW43_RS00770 158139 159590 + trk system potassium uptake protein trkH gene gene153 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00770 HW43_RS00775 HW43_00845 hemG hemG 159602 160147 + protoporphyrinogen IX dehydrogenase [menaquinone] catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX gene gene154 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00775 HW43_RS00780 HW43_00850 HW43_RS00780 160521 162076 + 16S ribosomal RNA rRNA gene155 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00780 HW43_RS00785 HW43_00855 HW43_RS00785 162133 162209 + tRNA-Ile tRNA gene156 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00785 HW43_RS00790 HW43_00860 HW43_RS00790 162252 162327 + tRNA-Ala tRNA gene157 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00790 HW43_RS00795 HW43_00865 HW43_RS00795 162502 165431 + 23S ribosomal RNA rRNA gene158 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00795 HW43_RS00800 HW43_00870 HW43_RS00800 165509 165624 + 5S ribosomal RNA rRNA gene159 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00800 HW43_RS00805 HW43_00875 HW43_RS00805 165728 166255 - molybdopterin-guanine dinucleotide biosynthesis protein B in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway gene gene160 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00805 HW43_RS00810 HW43_00880 mobA mobA 166237 166821 - molybdopterin-guanine dinucleotide biosynthesis protein MobA in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis gene gene161 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00810 HW43_RS00815 HW43_00885 HW43_RS00815 166891 167160 + hypothetical protein gene gene162 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00815 HW43_RS00820 HW43_00890 HW43_RS00820 167237 168223 + protein RdoA catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro%3B specific substrate in vivo has not been identified yet%3B plays a role in long-term cell survival and expression of surface appendages gene gene163 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00820 HW43_RS00825 HW43_00895 HW43_RS00825 168240 168866 + thiol:disulfide interchange protein DsbA gene gene164 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00825 HW43_RS00830 HW43_00900 HW43_RS00830 169021 170451 + hypothetical protein gene gene165 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00830 HW43_RS00835 HW43_00905 HW43_RS00835 170492 171424 - acyltransferase gene gene166 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00835 HW43_RS00840 HW43_24355 HW43_RS00840 171544 171786 - hypothetical protein gene gene167 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00840 HW43_RS00845 HW43_00915 HW43_RS00845 171788 174574 + DNA polymerase I gene gene168 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00845 HW43_RS00850 HW43_00920 HW43_RS00850 174956 175588 - GTP-binding protein gene gene169 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00850 HW43_RS00855 HW43_00925 HW43_RS00855 176170 176679 + der GTPase-activating protein YihI gene gene170 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00855 HW43_RS00860 HW43_00930 HW43_RS00860 176868 178241 + coproporphyrinogen III oxidase catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III gene gene171 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00860 HW43_RS00865 HW43_24360 HW43_RS00865 178431 178541 - hypothetical protein gene gene172 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00865 HW43_RS00870 HW43_00935 glnG glnG 178653 180062 - nitrogen regulation protein NR(I) response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes%3B interacts with sigma-54 gene gene173 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00870 HW43_RS00875 HW43_00940 glnL glnL 180074 181123 - PAS domain-containing two-component system sensor histidine kinase sensory histidine kinase in two-component regulatory system with GlnG%3B acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation gene gene174 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00875 HW43_RS00880 HW43_00945 glnA glnA 181297 182706 - glutamine synthetase forms a homododecamer%3B forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate%3B also functions in the assimilation of ammonia%3B highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues%3B addition of adenylyl groups results in inactivation of the enzyme gene gene175 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00880 HW43_RS00885 HW43_24365 HW43_RS00885 182685 182918 - hypothetical protein gene gene176 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00885 HW43_RS00890 HW43_00950 HW43_RS00890 183079 184902 + GTP-binding protein gene gene177 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00890 HW43_RS00895 HW43_00955 HW43_RS00895 185119 185829 + GntR family transcriptional regulator gene gene178 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00895 HW43_RS00900 HW43_00960 HW43_RS00900 185837 186817 + sugar phosphate isomerase gene gene179 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00900 HW43_RS00905 HW43_00965 HW43_RS00905 186919 188184 + transporter gene gene180 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00905 HW43_RS00910 HW43_00970 HW43_RS00910 188295 189083 - DeoR family transcriptional regulator gene gene181 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00910 HW43_RS00915 HW43_00975 HW43_RS00915 189123 190019 - sugar kinase gene gene182 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00915 HW43_RS00920 HW43_00980 HW43_RS00920 190192 191070 + NADH-dependent gamma-hydroxybutyrate dehydrogenase gene gene183 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00920 HW43_RS00925 HW43_00985 HW43_RS00925 191095 191982 + aldolase gene gene184 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00925 HW43_RS00930 HW43_00990 HW43_RS00930 192015 193025 + molecular chaperone GroES gene gene185 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00930 HW43_RS00935 HW43_00995 HW43_RS00935 193095 194528 + transporter gene gene186 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00935 HW43_RS00940 HW43_01000 HW43_RS00940 194627 195976 + shikimate transporter gene gene187 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00940 HW43_RS00945 HW43_01005 HW43_RS00945 195966 196853 + aldose epimerase gene gene188 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00945 HW43_RS00950 HW43_01010 HW43_RS00950 196994 197593 + alpha-D-glucose-1-phosphate phosphatase YihX gene gene189 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00950 HW43_RS00955 HW43_01015 HW43_RS00955 197587 198459 + membrane protein gene gene190 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00955 HW43_RS00960 HW43_01020 HW43_RS00960 198456 198893 + D-aminoacyl-tRNA deacylase hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr)%3B possible defense mechanism against a harmful effect of D-tyrosine gene gene191 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00960 HW43_RS00965 HW43_01025 HW43_RS00965 198938 199879 + hypothetical protein gene gene192 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00965 HW43_RS00970 HW43_01030 HW43_RS00970 199943 200851 - lipase gene gene193 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00970 HW43_RS00975 HW43_01035 HW43_RS00975 201080 201391 + hypothetical protein gene gene194 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00975 HW43_RS00980 HW43_01040 HW43_RS00980 201392 201682 + Cro/Cl family transcriptional regulator gene gene195 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00980 HW43_RS00985 HW43_01050 HW43_RS00985 202287 202505 + hypothetical protein gene gene196 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00985 HW43_RS00990 HW43_01055 HW43_RS00990 202725 202967 + hypothetical protein gene gene197 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00990 HW43_RS00995 HW43_01060 HW43_RS00995 202961 203077 + hypothetical protein gene gene198 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS00995 HW43_RS01000 HW43_01065 HW43_RS01000 203297 204226 - protein FdhE required for the formation of active formate dehydrogenase gene gene199 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01000 HW43_RS01005 HW43_01070 HW43_RS01005 204223 204858 - formate dehydrogenase cytochrome b556(fdo) subunit cytochrome b556(FDO) component%3B heme containing gene gene200 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01005 HW43_RS01010 HW43_01075 HW43_RS01010 204855 205757 - formate dehydrogenase-O iron-sulfur subunit beta subunit%3B involved in the use of formate as an electron donor during aerobic respiration%3B acts to transfer electrons from the major(alpha subunit) to the cytochrome b556(gamma subunit) gene gene201 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01010 HW43_RS01015 HW43_01080 HW43_RS01015 205770 208184 - formate dehydrogenase subunit alpha gene gene202 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01015 HW43_RS01020 HW43_01085 HW43_RS01020 208233 208820 - sulfate ABC transporter substrate-binding protein gene gene203 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01020 HW43_RS01025 HW43_01090 HW43_RS01025 209014 209847 + protein FdhD involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth gene gene204 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01025 HW43_RS01030 HW43_01095 HW43_RS01030 210000 211040 + hypothetical protein gene gene205 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01030 HW43_RS01035 HW43_01100 HW43_RS01035 211090 212838 - frv operon regulatory protein repressor of the frv operon%2C involved in phosphoenolpyruvate:sugar phosphotransferase system gene gene206 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01035 HW43_RS01040 HW43_01105 HW43_RS01040 212838 213908 - peptidase gene gene207 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01040 HW43_RS01045 HW43_01110 HW43_RS01045 213898 215349 - fructose-like PTS system EIIBC component gene gene208 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01045 HW43_RS01050 HW43_01115 HW43_RS01050 215360 215806 - PTS fructose transporter subunit EIIA with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars%3B possibly responsible for the sugar specificity of the system gene gene209 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01050 HW43_RS01055 HW43_01120 HW43_RS01055 216119 216433 - L-rhamnose mutarotase gene gene210 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01055 HW43_RS01060 HW43_01125 HW43_RS01060 216443 217267 - rhamnulose-1-phosphate aldolase gene gene211 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01060 HW43_RS01065 HW43_01130 HW43_RS01065 217509 218768 - L-rhamnose isomerase catalyzes the formation of L-rhamnulose from L-rhamnose gene gene212 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01065 HW43_RS01070 HW43_01135 rhaB rhaB 218765 220234 - rhamnulokinase catalyzes the ATP-dependent phosphorylation of rhamnulose gene gene213 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01070 HW43_RS01075 HW43_24370 HW43_RS01075 220313 220462 + hypothetical protein gene gene214 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01075 HW43_RS01080 HW43_01145 HW43_RS01080 220522 221358 + transcriptional activator RhaS gene gene215 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01080 HW43_RS01085 HW43_01150 HW43_RS01085 221432 222280 + HTH-type transcriptional activator RhaR activates the expression of rhaRS in response to L-rhamnose gene gene216 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01085 HW43_RS01090 HW43_01155 HW43_RS01090 222277 223311 - l-rhamnose-proton symporter transports L-rhamnose and L-lyxose into the cell gene gene217 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01090 HW43_RS01095 HW43_01160 HW43_RS01095 223596 224216 + superoxide dismutase [Mn] SodA%3B manganese binding%3B only present under aerobic conditions%3B destroys free radicals gene gene218 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01095 HW43_RS01100 HW43_24375 HW43_RS01100 224257 224373 - hypothetical protein gene gene219 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01100 HW43_RS01105 HW43_01170 HW43_RS01105 224476 225459 + 2-keto-3-deoxygluconate permease transports degraded pectin products into the bacterial cell gene gene220 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01105 HW43_RS01110 HW43_01175 HW43_RS01110 225608 226282 + hypothetical protein gene gene221 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01110 HW43_RS01115 HW43_01180 cpxA cpxA 226388 227761 - two-component system sensor histidine kinase part of two-component CpxA/CpxR system%3B senses envelope stress%3B upregulates a number of periplasmic folding and trafficking factors gene gene222 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01115 HW43_RS01120 HW43_01185 HW43_RS01120 227758 228456 - two-component system response regulator response regulator in two-component regulatory system with CpxA%3B part of the envelope stress response system gene gene223 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01120 HW43_RS01125 HW43_01190 cpxP cpxP 228606 229106 + periplasmic protein CpxP repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA%3B CpxP is degraded by DegP protease especially in the presence of misfolded substrates gene gene224 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01125 HW43_RS01130 HW43_01195 fieF fieF 229255 230157 + ferrous iron and zinc transporter member of cation diffusion facilitator family%3B CDF%3B membrane-bound%3B induced by both zinc and iron%2C but does not induce resistance to zinc%3B can transport zinc(II) in a proton-dependent manner%3B instead this protein induces iron resistance%3B forms dimers gene gene225 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01130 HW43_RS01135 HW43_01200 HW43_RS01135 230338 231300 + ATP-dependent 6-phosphofructokinase catalyzes the formation of D-fructose 1%2C6-bisphosphate from D-fructose 6-phosphate in glycolysis gene gene226 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01135 HW43_RS01140 HW43_01205 HW43_RS01140 231620 232609 + sulfate-binding protein gene gene227 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01140 HW43_RS01145 HW43_01210 HW43_RS01145 232716 233471 + CDP-diacylglycerol pyrophosphatase gene gene228 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01145 HW43_RS01150 HW43_01215 HW43_RS01150 233526 234293 - triosephosphate isomerase Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate gene gene229 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01150 HW43_RS01155 HW43_01220 HW43_RS01155 234401 235000 - hypothetical protein gene gene230 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01155 HW43_RS01160 HW43_01225 HW43_RS01160 235101 235541 + membrane protein gene gene231 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01160 HW43_RS01165 HW43_01230 HW43_RS01165 235753 236052 + hypothetical protein gene gene232 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01165 HW43_RS01170 HW43_01235 HW43_RS01170 236079 236507 + universal stress protein D with UspC and Usp E is involved in resistance to UV radiation gene gene233 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01170 HW43_RS01175 HW43_01240 HW43_RS01175 236512 237258 - ferredoxin--NADP reductase gene gene234 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01175 HW43_RS01180 HW43_01245 HW43_RS01180 237355 238365 - fructose 1%2C6-bisphosphatase gene gene235 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01180 HW43_RS01185 HW43_01250 glpK glpK 238498 240006 - glycerol kinase Converts glycerol and ADP to glycerol-3-phosphate and ADP gene gene236 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01185 HW43_RS01190 HW43_01255 HW43_RS01190 240029 240874 - glycerol uptake facilitator protein involved in the transport of glycerol into the cell gene gene237 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01190 HW43_RS01195 HW43_01260 HW43_RS01195 241305 241544 + cell division protein ZapB interacts with FisZ and is necessary for Z-ring formation gene gene238 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01195 HW43_RS01200 HW43_01265 HW43_RS01200 241629 242114 - ribonuclease E activity regulator RraA regulator of RNase E%3B increases half-life and abundance of RNAs%3B interacts with RNase E possibly inhibiting catalytic activity gene gene239 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01200 HW43_RS01205 HW43_01270 HW43_RS01205 242207 243133 - 1%2C4-dihydroxy-2-naphthoate octaprenyltransferase catalyzes the formation of dimethylmenaquinone from 1%2C4-dihydroxy-2-naphthoate and octaprenyl diphosphate gene gene240 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01205 HW43_RS01210 HW43_01275 hslU hslU 243200 244531 - ATP-dependent protease ATPase subunit HslU heat shock protein involved in degradation of misfolded proteins gene gene241 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01210 HW43_RS01215 HW43_01280 HW43_RS01215 244541 245071 - ATP-dependent protease subunit HslV gene gene242 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01215 HW43_RS01220 HW43_01285 HW43_RS01220 245164 246018 - cell division protein FtsN gene gene243 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01220 HW43_RS01225 HW43_01290 HW43_RS01225 246215 247240 - transcriptional regulator negatively controls the transcription initiation of genes such as deoCABD%2C udp%2C and cdd encoding catabolizing enzymes and nupC%2C nupG%2C and tsx encoding transporting and pore-forming proteins gene gene244 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01225 HW43_RS01230 HW43_01295 HW43_RS01230 247396 249594 - primosome assembly protein PriA binding of PriA to forked DNA starts the assembly of the primosome%2C also possesses 3'-5' helicase activity gene gene245 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01230 HW43_RS01235 HW43_01300 rpmE rpmE 249797 250009 + 50S ribosomal protein L31 RpmE%3B there appears to be two types of ribosomal proteins L31 in bacterial genomes%3B some contain a CxxC motif while others do not%3B Bacillus subtilis has both types%3B the proteins in this cluster have the CXXC motif%3B RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth%3B expression of ytiA is controlled by a zinc-specific transcriptional repressor%3B RpmE contains one zinc ion and a CxxC motif is responsible for this binding%3B forms an RNP particle along with proteins L5%2C L18%2C and L25 and 5S rRNA%3B found crosslinked to L2 and L25 and EF-G%3B may be near the peptidyltransferase site of the 50S ribosome gene gene246 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01235 HW43_RS01240 HW43_01305 HW43_RS01240 250169 254353 + RHS element protein RhsA gene gene247 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01240 HW43_RS01245 HW43_24385 HW43_RS01245 254355 254591 + hypothetical protein gene gene248 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01245 HW43_RS01250 HW43_24390 HW43_RS01250 254647 254961 - transposase gene gene249 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01250 HW43_RS01255 HW43_24395 HW43_RS01255 254955 255140 - transposase gene gene250 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01255 HW43_RS01260 HW43_01320 HW43_RS01260 255167 255439 - Insertion element iso-IS1N protein insA gene gene251 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01260 HW43_RS01265 HW43_24400 HW43_RS01265 255362 255655 + hypothetical protein gene gene252 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01265 HW43_RS01270 HW43_01325 HW43_RS01270 255584 256192 - hypothetical protein gene gene253 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01270 HW43_RS01275 HW43_01330 HW43_RS01275 256252 256569 - met repressor when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis gene gene254 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01275 HW43_RS01280 HW43_01335 HW43_RS01280 256846 258006 + cystathionine gamma-synthase catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine gene gene255 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01280 HW43_RS01285 HW43_01340 metL metL 258009 260441 + bifunctional aspartate kinase II/homoserine dehydrogenase II multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine%3B functions in a number of amino acid biosynthetic pathways gene gene256 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01285 HW43_RS01290 HW43_24405 HW43_RS01290 260580 260714 - hypothetical protein gene gene257 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01290 HW43_RS01295 HW43_01350 metF metF 260790 261680 + 5%2C10-methylenetetrahydrofolate reductase MTHFR%3B catalyzes NADH-linked reduction of 5%2C10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor gene gene258 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01295 HW43_RS01300 HW43_01355 HW43_RS01300 262009 264189 + catalase/hydroperoxidase HPI(I) gene gene259 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01300 HW43_RS01305 HW43_01360 HW43_RS01305 264283 265188 + permease gene gene260 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01305 HW43_RS01310 HW43_01365 HW43_RS01310 265215 265832 - hypothetical protein gene gene261 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01310 HW43_RS01315 HW43_24410 HW43_RS01315 265944 266063 - hypothetical protein gene gene262 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01315 HW43_RS01320 HW43_01370 gldA gldA 266107 267210 - glycerol dehydrogenase forms dimers and octamers%3B involved in conversion of glycerol to dihydroxy-acetone gene gene263 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01320 HW43_RS01325 HW43_01375 HW43_RS01325 267221 267883 - fructose-6-phosphate aldolase similar to transaldolase from Escherichia coli%3B many organisms have multiple copies gene gene264 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01325 HW43_RS01330 HW43_01380 HW43_RS01330 267895 270396 - PTS fructose transporter subunit IIA Phosphotransferase system%2C enzyme I%3B transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein HPr%3B HPr transfers the phosphoryl group to subunit A%3B subunit IIA transfers a phosphoryl group to subunit IIB%3B subunit IIB transfers the phosphoryl group to the substrate%3B part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active-transport system gene gene265 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01330 HW43_RS01335 HW43_01385 HW43_RS01335 270705 271784 + fructose-like permease IIC component 2 gene gene266 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01335 HW43_RS01340 HW43_01390 HW43_RS01340 271799 272119 + fructose-like phosphotransferase enzyme IIB component 2 FrwB with FrwC%2C FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell%3B cytoplasmic protein that interacts with complex EIIA%3B contains the second phosphorylation site of the PTS gene gene267 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01340 HW43_RS01345 HW43_01395 pflD pflD 272170 274467 + formate acetyltransferase involved in production of D-lactate from glucose under microaerobic conditions%3B cytoplasmic protein gene gene268 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01345 HW43_RS01350 HW43_01400 HW43_RS01350 274433 275311 + pyruvate formate lyase II activase gene gene269 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01350 HW43_RS01355 HW43_01405 HW43_RS01355 275313 275654 + PTS fructose transporter subunit IIB FrwD with FrwB%2C FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell%3B phosphorylated by EIIA%3B FrwB homolog gene gene270 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01355 HW43_RS01360 HW43_01410 HW43_RS01360 275641 276492 - AraC family transcriptional regulator gene gene271 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01360 HW43_RS01365 HW43_01415 HW43_RS01365 276641 278374 - membrane protein gene gene272 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01365 HW43_RS01370 HW43_01420 HW43_RS01370 278557 281208 - phosphoenolpyruvate carboxylase catalyzes the formation of oxaloacetate from phosphoenolpyruvate gene gene273 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01370 HW43_RS01375 HW43_01425 HW43_RS01375 281560 282711 - acetylornithine deacetylase catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis gene gene274 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01375 HW43_RS01380 HW43_01430 HW43_RS01380 282865 283869 + N-acetyl-gamma-glutamyl-phosphate reductase gene gene275 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01380 HW43_RS01385 HW43_01435 HW43_RS01385 283880 284653 + acetylglutamate kinase gene gene276 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01385 HW43_RS01390 HW43_01440 HW43_RS01390 284714 286087 + argininosuccinate lyase catalyzes the formation of arginine from (N-L-arginino)succinate gene gene277 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01390 HW43_RS01395 HW43_01445 HW43_RS01395 286586 287800 + bifunctional D-altronate/D-mannonate dehydratase starvation-sensing protein%3B maybe involved in homoserine lactone degradation gene gene278 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01395 HW43_RS01400 HW43_01450 HW43_RS01400 287867 289150 + transporter gene gene279 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01400 HW43_RS01405 HW43_01455 HW43_RS01405 289402 290319 + hydrogen peroxide-inducible genes activator Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG%2C gor%2C ahpC%2C ahpF%2C oxyS%2C dps%2C fur and grxA gene gene280 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01405 HW43_RS01410 HW43_01460 HW43_RS01410 290302 291702 - soluble pyridine nucleotide transhydrogenase catalyzes the conversion of NADPH to NADH gene gene281 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01410 HW43_RS01415 HW43_01465 HW43_RS01415 292036 292683 + transcriptional regulator negatively controls the expression of fabA and fabB%2C genes involved in the unsaturated fatty acid biosynthesis gene gene282 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01415 HW43_RS01420 HW43_01470 HW43_RS01420 292683 293042 + hypothetical protein gene gene283 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01420 HW43_RS01425 HW43_01475 HW43_RS01425 293082 294182 - tRNA/tmRNA (uracil-C(5))-methyltransferase catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs gene gene284 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01425 HW43_RS01430 HW43_01480 btuB btuB 294551 296395 + vitamin B12/cobalamin outer membrane transporter involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space gene gene285 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01430 HW43_RS01435 HW43_01485 HW43_RS01435 296409 297197 + glutamate racemase converts L-glutamate to D-glutamate%2C a component of peptidoglycan gene gene286 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01435 HW43_RS01440 HW43_01490 HW43_RS01440 297569 299124 + 16S ribosomal RNA rRNA gene287 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01440 HW43_RS01445 HW43_01495 HW43_RS01445 299198 299273 + tRNA-Glu tRNA gene288 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01445 HW43_RS01450 HW43_01500 HW43_RS01450 299458 302387 + 23S ribosomal RNA rRNA gene289 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01450 HW43_RS01455 HW43_01505 HW43_RS01455 302465 302580 + 5S ribosomal RNA rRNA gene290 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01455 HW43_RS01460 HW43_01510 murB murB 302883 303911 + UDP-N-acetylenolpyruvoylglucosamine reductase catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis gene gene291 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01460 HW43_RS01465 HW43_01515 HW43_RS01465 303908 304873 + bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor catalyzes the formation of biotinyl-5'-AMP%2C also acts as a transcriptional repressor of the biotin operon gene gene292 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01465 HW43_RS01470 HW43_01520 HW43_RS01470 304902 305858 - type I pantothenate kinase gene gene293 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01470 HW43_RS01475 HW43_24415 HW43_RS01475 306039 306194 - hypothetical protein gene gene294 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01475 HW43_RS01480 HW43_01525 HW43_RS01480 306214 306289 + tRNA-Thr tRNA gene295 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01480 HW43_RS01485 HW43_01530 HW43_RS01485 306298 306382 + tRNA-Tyr tRNA gene296 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01485 HW43_RS01490 HW43_01535 HW43_RS01490 306499 306573 + tRNA-Gly tRNA gene297 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01490 HW43_RS01495 HW43_01540 HW43_RS01495 306580 306655 + tRNA-Thr tRNA gene298 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01495 HW43_RS01500 HW43_01545 tuf tuf 306770 307954 + translation elongation factor EF-Tu 2 EF-Tu%3B promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B when the tRNA anticodon matches the mRNA codon%2C GTP hydrolysis results%3B the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts%3B many prokaryotes have two copies of the gene encoding EF-Tu gene gene299 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01500 HW43_RS01505 HW43_01550 secE secE 308184 308567 + protein translocase subunit SecE forms a complex with SecY and SecG%3B SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane%2C a process driven by ATP and a proton-motive force gene gene300 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01505 HW43_RS01510 HW43_01555 nusG nusG 308569 309114 + transcription termination/antitermination protein NusG Modulates Rho-dependent transcription termination gene gene301 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01510 HW43_RS01515 HW43_01560 HW43_RS01515 309273 309701 + 50S ribosomal protein L11 gene gene302 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01515 HW43_RS01520 HW43_01565 HW43_RS01520 309705 310409 + 50S ribosomal protein L1 gene gene303 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01520 HW43_RS01525 HW43_01570 rplJ rplJ 310822 311319 + 50S ribosomal protein L10 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit gene gene304 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01525 HW43_RS01530 HW43_01575 rplL rplL 311386 311751 + 50S ribosomal protein L7/L12 present in two forms%3B L12 is normal%2C while L7 is aminoacylated at the N-terminal serine%3B the only multicopy ribosomal protein%3B 4:1 ratio of L7/L12 per ribosome%3B two L12 dimers bind L10%3B critically important for translation efficiency and fidelity%3B stimulates GTPase activity of translation factors gene gene305 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01530 HW43_RS01535 HW43_01580 rpoB rpoB 312071 316099 + DNA-directed RNA polymerase subunit beta DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme gene gene306 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01535 HW43_RS01540 HW43_01585 HW43_RS01540 316176 320399 + DNA-directed RNA polymerase subunit beta' DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter gene gene307 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01540 HW43_RS01545 HW43_01590 thiH thiH 320640 321773 - thiamine biosynthesis protein ThiH in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS%3B with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine%2C cysteine and 1-deoxy-D-xylulose-5-phosphate%3B forms a complex with ThiG%3B contains an iron-sulfur center gene gene308 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01545 HW43_RS01550 HW43_01595 HW43_RS01550 321770 322540 - thiazole synthase gene gene309 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01550 HW43_RS01555 HW43_01600 HW43_RS01555 322542 322742 - thiamine biosynthesis protein ThiS with ThiF%2C ThiG%2C and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate gene gene310 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01555 HW43_RS01560 HW43_01605 HW43_RS01560 322726 323481 - molybdopterin biosynthesis protein MoeB ATP-dependent adenylate transferase%2C transfers adenyl moiety to the MoeD subunit of molybdopterin synthase gene gene311 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01560 HW43_RS01565 HW43_01610 HW43_RS01565 323474 324109 - thiamine-phosphate synthase catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate gene gene312 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01565 HW43_RS01570 HW43_01615 HW43_RS01570 324109 326004 - phosphomethylpyrimidine synthase ThiC catalyzes the formation of 4-amino-2-methyl-5-phosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole and S-adenosyl-L-methionine in thiamine biosynthesis gene gene313 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01570 HW43_RS01575 HW43_01620 HW43_RS01575 326238 326714 - regulator of sigma D binds specifically to the major sigma factor sigma 70%3B active in stationary phase gene gene314 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01575 HW43_RS01580 HW43_01625 nudC nudC 326809 327582 + NADH pyrophosphatase can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH%3B requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates gene gene315 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01580 HW43_RS01585 HW43_01630 hemE hemE 327622 328686 + uroporphyrinogen decarboxylase catalyzes the formation of coproporphyrinogen from uroporphyrinogen III gene gene316 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01585 HW43_RS01590 HW43_01635 HW43_RS01590 328696 329367 + endonuclease V Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA%3B cleaves DNA containing urea residues%2C AP sites%2C base mismatches%2C insertion/deletion mismatches%2C flaps%2C and pseudo-Y structures gene gene317 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01590 HW43_RS01595 HW43_01640 HW43_RS01595 329410 330000 + hypothetical protein gene gene318 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01595 HW43_RS01600 HW43_01645 HW43_RS01600 330187 330459 + DNA-binding protein HU-alpha gene gene319 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01600 HW43_RS01605 HW43_01650 HW43_RS01605 330472 331167 + membrane protein gene gene320 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01605 HW43_RS01610 HW43_01655 zraP zraP 331169 331594 - zinc resistance-associated protein gene gene321 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01610 HW43_RS01615 HW43_01660 HW43_RS01615 331832 333208 + two-component system sensor histidine kinase gene gene322 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01615 HW43_RS01620 HW43_01665 HW43_RS01620 333205 334530 + acetoacetate metabolism regulatory protein AtoC DNA-binding response regulator in two-component regulatory system with ZraS%3B response regulator/sigma54 interaction protein gene gene323 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01620 HW43_RS01625 HW43_01670 HW43_RS01625 334527 335816 - phosphoribosylamine--glycine ligase catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis gene gene324 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01625 HW43_RS01630 HW43_01675 purH purH 335828 337417 - bifunctional purine biosynthesis protein PurH involved in de novo purine biosynthesis gene gene325 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01630 HW43_RS01635 HW43_RS01635 HW43_RS01635 337371 337556 - hypothetical protein gene gene326 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01635 HW43_RS01640 HW43_RS01640 HW43_RS01640 337490 337693 - hypothetical protein gene gene327 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01640 HW43_RS01645 HW43_01680 HW43_RS01645 338030 339585 + 16S ribosomal RNA rRNA gene328 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01645 HW43_RS01650 HW43_01685 HW43_RS01650 339659 339734 + tRNA-Glu tRNA gene329 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01650 HW43_RS01655 HW43_01690 HW43_RS01655 339919 342843 + 23S ribosomal RNA rRNA gene330 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01655 HW43_RS01660 HW43_01695 HW43_RS01660 342926 343041 + 5S ribosomal RNA rRNA gene331 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01660 HW43_RS01665 HW43_01700 HW43_RS01665 343156 343599 - acetyltransferase gene gene332 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01665 HW43_RS01670 HW43_01705 HW43_RS01670 343756 344685 + homoserine O-succinyltransferase catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis gene gene333 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01670 HW43_RS01675 HW43_01710 HW43_RS01675 344954 346555 + malate synthase Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle gene gene334 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01675 HW43_RS01680 HW43_01715 HW43_RS01680 346585 347889 + isocitrate lyase gene gene335 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01680 HW43_RS01685 HW43_01720 aceK aceK 348072 349808 + isocitrate dehydrogenase catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity%3B unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol gene gene336 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01685 HW43_RS01690 HW43_01725 HW43_RS01690 349777 351351 - hypothetical protein gene gene337 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01690 HW43_RS01695 HW43_01730 HW43_RS01695 351668 352492 - acetate operon repressor regulates the glyoxylate bypass operon (aceBAK)%2C which encodes isocitrate lyase%2C malate synthase and isocitrate dehydrogenase kinase/phosphorylase gene gene338 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01695 HW43_RS01700 HW43_01735 metH metH 352692 356375 + B12-dependent methionine synthase one of two methionine synthases in Escherichia coli%3B MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine%3B requires zinc for activity gene gene339 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01700 HW43_RS01705 HW43_01740 HW43_RS01705 356595 358226 + transporter gene gene340 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01705 HW43_RS01710 HW43_01745 HW43_RS01710 358317 359006 - peptidase E peptidase E%3B catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue%3B belongs to peptidase S51 family gene gene341 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01710 HW43_RS01715 HW43_01750 HW43_RS01715 359218 360090 + 23S rRNA pseudouridine synthase F catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA gene gene342 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01715 HW43_RS01720 HW43_01755 HW43_RS01720 360091 360363 - hypothetical protein gene gene343 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01720 HW43_RS01725 HW43_01760 HW43_RS01725 360893 362020 + hypothetical protein gene gene344 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01725 HW43_RS01730 HW43_01765 HW43_RS01730 362026 362817 + nucleotidyltransferase gene gene345 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01730 HW43_RS01735 HW43_01770 HW43_RS01735 362853 363779 - zeta toxin%3B poison-antidote element gene gene346 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01735 HW43_RS01740 HW43_01775 HW43_RS01740 363924 365273 - aspartate kinase catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP%3B functions in amino acid biosynthesis%3B lysine sensitive gene gene347 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01740 HW43_RS01745 HW43_01780 pgi pgi 365798 367447 + glucose-6-phosphate isomerase functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis%3B catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate%3B member of PGI family gene gene348 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01745 HW43_RS01750 HW43_01785 HW43_RS01750 367802 368044 + polysaccharide production threonine-rich protein gene gene349 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01750 HW43_RS01755 HW43_01790 HW43_RS01755 368158 368796 + hypothetical protein gene gene350 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01755 HW43_RS01760 HW43_01795 HW43_RS01760 368793 369530 + hypothetical protein gene gene351 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01760 HW43_RS01765 HW43_01800 HW43_RS01765 369530 371626 + membrane protein gene gene352 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01765 HW43_RS01770 HW43_01805 HW43_RS01770 371673 371951 - periplasmic protein gene gene353 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01770 HW43_RS01775 HW43_24420 HW43_RS01775 371952 372095 + hypothetical protein gene gene354 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01775 HW43_RS01780 HW43_01815 HW43_RS01780 372221 372631 + protein PsiE gene gene355 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01780 HW43_RS01785 HW43_01820 xylE xylE 372675 374150 - D-xylose transporter xylose/proton symporter%3B member of the major facilitator superfamily (MFS) of transporter gene gene356 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01785 HW43_RS01790 HW43_01825 malG malG 374522 375412 - maltose ABC transporter permease with MalKFE is involved in the transport of maltose into the cell gene gene357 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01790 HW43_RS01795 HW43_01830 malF malF 375427 376971 - maltose ABC transporter permease with MalKGE is involved in maltose transport into the cell gene gene358 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01795 HW43_RS01800 HW43_01835 malE malE 377125 378315 - maltose-binding periplasmic protein functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis gene gene359 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01800 HW43_RS01805 HW43_01840 HW43_RS01805 378408 378503 - sugar ABC transporter gene gene360 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01805 HW43_RS01810 HW43_01845 HW43_RS01810 378680 379795 + maltose/maltodextrin import ATP-binding protein MalK with malEFG is involved in import of maltose/maltodextrin gene gene361 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01810 HW43_RS01815 HW43_01850 lamB lamB 379867 381207 + maltoporin porin involved in the transport of maltose and maltodextrins gene gene362 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01815 HW43_RS01820 HW43_01855 HW43_RS01820 381450 382370 + maltose operon protein gene gene363 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01820 HW43_RS01825 HW43_01860 HW43_RS01825 382599 382793 + hypothetical protein gene gene364 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01825 HW43_RS01830 HW43_01865 HW43_RS01830 382851 384179 + hypothetical protein in E. coli%2C some yjbl mutations have been reported as suppressors of dnaG mutations gene gene365 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01830 HW43_RS01835 HW43_01870 ubiC ubiC 384402 384899 + Chorismate pyruvate-lyase catalyzes the formation of 4-hydroxybenzoate from chorismate gene gene366 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01835 HW43_RS01840 HW43_01875 ubiA ubiA 384912 385784 + 4-hydroxybenzoate octaprenyltransferase catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate%2C as part of the ubiquinone biosynthesis pathway gene gene367 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01840 HW43_RS01845 HW43_01880 HW43_RS01845 385939 388362 - glycerol-3-phosphate acyltransferase PlsB%3B catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA gene gene368 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01845 HW43_RS01850 HW43_01885 HW43_RS01850 388533 388901 + diacylglycerol kinase catalyzes the phosphorylation of diacylglycerol to form diacylglycerol phosphate gene gene369 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01850 HW43_RS01855 HW43_01890 HW43_RS01855 389011 389619 + LexA repressor Represses a number of genes involved in the response to DNA damage gene gene370 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01855 HW43_RS01860 HW43_01895 HW43_RS01860 389692 391017 + MATE family efflux transporter gene gene371 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01860 HW43_RS01865 HW43_01900 HW43_RS01865 391133 391342 + stress-induced protein%2C UPF0337 family gene gene372 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01865 HW43_RS01870 HW43_01905 HW43_RS01870 391384 391899 - zinc uptake regulation protein Acts as a negative controlling element%2C employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB gene gene373 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01870 HW43_RS01875 HW43_01910 HW43_RS01875 392217 393233 + hypothetical protein gene gene374 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01875 HW43_RS01880 HW43_01915 HW43_RS01880 393641 394633 + tRNA-dihydrouridine synthase A gene gene375 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01880 HW43_RS01885 HW43_01920 pspG pspG 394767 395009 + phage-shock protein coordinately regulated along with pspA%3B PspF-dependent induction in response to secretin overexpression in Yersinia gene gene376 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01885 HW43_RS01890 HW43_01925 HW43_RS01890 395175 396158 - quinone oxidoreductase gene gene377 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01890 HW43_RS01895 HW43_01930 HW43_RS01895 396241 397656 + replicative DNA helicase unwinds double stranded DNA gene gene378 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01895 HW43_RS01900 HW43_01935 alr alr 397709 398788 + alanine racemase biosynthetic converts L-alanine to D-alanine which is used in cell wall biosynthesis%3B binds one pyridoxal phosphate per monomer%3B forms a homodimer gene gene379 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01900 HW43_RS01905 HW43_01940 HW43_RS01905 399041 400234 + aromatic amino acid aminotransferase catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate gene gene380 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01905 HW43_RS01910 HW43_01945 HW43_RS01910 400456 400959 - hypothetical protein gene gene381 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01910 HW43_RS01915 HW43_01950 aphA aphA 401361 402074 + phosphotransferase Class B%3B non-specific%3B catalyzes the dephosphorylation of organic phosphomonoesters%3B also has phosphotransferase activity gene gene382 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01915 HW43_RS01920 HW43_01955 HW43_RS01920 402185 402601 + thiamin phosphate synthase gene gene383 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01920 HW43_RS01925 HW43_01960 HW43_RS01925 402605 402961 + hypothetical protein gene gene384 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01925 HW43_RS01930 HW43_01965 HW43_RS01930 402996 405818 - UvrABC system protein A gene gene385 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01930 HW43_RS01935 HW43_01970 HW43_RS01935 406072 406608 + single-stranded DNA-binding protein binds to single stranded DNA and PriA helcase facilitate replication restart gene gene386 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01935 HW43_RS01940 HW43_01975 HW43_RS01940 406707 406988 - membrane protein gene gene387 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01940 HW43_RS01945 HW43_01980 HW43_RS01945 407418 409004 + hypothetical protein gene gene388 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01945 HW43_RS01950 HW43_01985 HW43_RS01950 409007 409330 - regulatory protein SoxS regulates genes involved in response to oxidative stress gene gene389 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01950 HW43_RS01955 HW43_01990 HW43_RS01955 409416 409880 + redox-sensitive transcriptional activator SoxR gene gene390 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01955 HW43_RS01960 HW43_01995 HW43_RS01960 410426 411775 + guanine/hypoxanthine permease GhxP gene gene391 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01960 HW43_RS01965 HW43_02000 HW43_RS01965 411926 413575 + sodium:proton antiporter gene gene392 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01965 HW43_RS01970 HW43_02005 HW43_RS01970 413729 415021 - hypothetical protein gene gene393 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01970 HW43_RS01975 HW43_02010 actP actP 415199 416848 - cation/acetate symporter ActP member of the sodium:solute symporter family%3B cotranscribed with the acs gene which encodes acetyl coenzyme A synthase%3B mutations affect acetate uptake gene gene394 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01975 HW43_RS01980 HW43_02015 HW43_RS01980 416845 417159 - hypothetical protein gene gene395 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01980 HW43_RS01985 HW43_02020 HW43_RS01985 417359 419317 - acetyl-CoA synthetase Acs%3B catalyzes the conversion of acetate and CoA to acetyl-CoA gene gene396 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01985 HW43_RS01990 HW43_02025 nrfA nrfA 419709 421145 + cytochrome c-552 catalyzes the formate-dependent reduction of nitrite to ammonia%3B cytochrome C552 gene gene397 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01990 HW43_RS01995 HW43_02030 HW43_RS01995 421190 421756 + cytochrome C nitrite reductase pentaheme subunit part of nitrite reductase complex%3B NrfB is active at high nitrate conditions%3B NrfA%2C B%2C C%2C and D are essential for the formate-dependent nitrite reduction to ammonia gene gene398 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS01995 HW43_RS02000 HW43_02035 HW43_RS02000 421753 422424 + formate-dependent nitrite reductase subunit NrfC 4Fe4S subunit%3B may be involved in the transfer of electrons from quinones to the c-type cytochromes gene gene399 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02000 HW43_RS02005 HW43_02040 HW43_RS02005 422421 423377 + protein NrfD membrane protein%2C may be involved in the transfer of electrons from quinones to c-type cytochromes gene gene400 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02005 HW43_RS02010 HW43_02045 HW43_RS02010 423508 425115 + heme lyase subunit NrfE with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552 gene gene401 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02010 HW43_RS02015 HW43_02050 HW43_RS02015 425108 425491 + formate-dependent nitrite reductase complex subunit NrfF gene gene402 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02015 HW43_RS02020 HW43_02055 HW43_RS02020 425488 426084 + formate-dependent nitrite reductase complex subunit NrfG gene gene403 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02020 HW43_RS02025 HW43_02060 HW43_RS02025 426426 427739 + proton glutamate symport protein gene gene404 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02025 HW43_RS02030 HW43_02065 HW43_RS02030 427817 428506 - hypothetical protein gene gene405 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02030 HW43_RS02035 HW43_02070 HW43_RS02035 428600 430279 - formate dehydrogenase subunit alpha gene gene406 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02035 HW43_RS02040 HW43_02075 HW43_RS02040 430328 430747 - spermidine/putrescine ABC transporter substrate-binding protein gene gene407 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02040 HW43_RS02045 HW43_02080 HW43_RS02045 430945 432411 - transporter part of a multidrug efflux system involved in resistance to acriflavin%2C puromycin%2C erytjhromycin and tetraphenylarsonium chloride%3B member of the outer membrane factor (OMF) family gene gene408 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02045 HW43_RS02050 HW43_02085 HW43_RS02050 432408 434459 - multidrug transporter possibly part of a tripartite efflux system composed of MdtN%2C MdtO and MdtP which could be involved in resistance to puromycin%2C acriflavine and tetraphenylarsonium chloride gene gene409 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02050 HW43_RS02055 HW43_02090 HW43_RS02055 434459 435490 - multidrug resistance protein MdtN with MdtO and MdtP is involved in resistance to puromycin%2C acriflavine and tetraphenylarsonium chloride gene gene410 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02055 HW43_RS02060 HW43_02095 HW43_RS02060 435509 435784 - hypothetical protein gene gene411 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02060 HW43_RS02065 HW43_02100 HW43_RS02065 435993 437978 - hypothetical protein gene gene412 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02065 HW43_RS02070 HW43_02105 HW43_RS02070 438251 439180 - D-allose kinase gene gene413 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02070 HW43_RS02075 HW43_02110 HW43_RS02075 439164 439859 - D-allulose-6-phosphate 3-epimerase gene gene414 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02075 HW43_RS02080 HW43_02115 HW43_RS02080 439870 440850 - D-allose ABC transporter permease gene gene415 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02080 HW43_RS02085 HW43_02120 HW43_RS02085 440829 442361 - cytochrome C6 with AlsBC acts to import allose into the cell%3B AlsA contain 2 ATP-binding domains gene gene416 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02085 HW43_RS02090 HW43_02125 HW43_RS02090 442488 443423 - cytochrome C gene gene417 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02090 HW43_RS02095 HW43_02130 HW43_RS02095 443482 444372 - RpiR family transcriptional regulator involved in rpiB and als operon repression gene gene418 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02095 HW43_RS02100 HW43_02135 HW43_RS02100 444732 445181 + ribose-5-phosphate isomerase B gene gene419 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02100 HW43_RS02105 HW43_02140 HW43_RS02105 445250 445579 + periplasmic protein gene gene420 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02105 HW43_RS02110 HW43_02145 phnP phnP 445726 446484 - phosphonate metabolism protein PhnP required for the use of phosphonates and phosphite as phosphorus sources gene gene421 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02110 HW43_RS02115 HW43_02150 HW43_RS02115 446486 446920 - protein PhnO PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids%3B part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source%3B Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role gene gene422 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02115 HW43_RS02120 HW43_02155 HW43_RS02120 446907 447464 - ribose 1%2C5-bisphosphokinase gene gene423 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02120 HW43_RS02125 HW43_02160 HW43_RS02125 447464 448600 - phosphonate metabolism protein PhnM gene gene424 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02125 HW43_RS02130 HW43_02165 HW43_RS02130 448597 449277 - phosphonate ABC transporter ATP-binding protein gene gene425 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02130 HW43_RS02135 HW43_02170 phnK phnK 449388 450146 - phosphonate C-P lyase gene gene426 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02135 HW43_RS02140 HW43_02175 HW43_RS02140 450143 450988 - carbon-phosphorus lyase complex subunit PhnJ gene gene427 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02140 HW43_RS02145 HW43_02180 HW43_RS02145 450981 452045 - carbon-phosphorus lyase complex subunit PhnI required for the use of phosphonate and phosphite gene gene428 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02145 HW43_RS02150 HW43_02185 phnH phnH 452045 452629 - phosphonate C-P lyase system protein PhnH gene gene429 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02150 HW43_RS02155 HW43_02190 HW43_RS02155 452626 453078 - phosphonate C-P lyase system protein PhnG gene gene430 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02155 HW43_RS02160 HW43_02195 HW43_RS02160 453079 453804 - transcriptional regulator may be involved in phosphonate uptake and biodegradation gene gene431 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02160 HW43_RS02165 HW43_02200 HW43_RS02165 453825 454604 - phosphonate ABC transporter permease gene gene432 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02165 HW43_RS02170 HW43_02205 HW43_RS02170 454710 455726 - phosphonate ABC transporter substrate-binding protein with PhnCE is involved in the transport of phosphonates gene gene433 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02170 HW43_RS02175 HW43_02210 HW43_RS02175 455751 456539 - phosphonate ABC transporter ATP-binding protein gene gene434 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02175 HW43_RS02180 HW43_02215 HW43_RS02180 456672 457115 - hypothetical protein gene gene435 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02180 HW43_RS02185 HW43_02220 HW43_RS02185 457275 457610 - protein PhnA gene gene436 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02185 HW43_RS02190 HW43_02225 HW43_RS02190 458012 460240 + hypothetical protein gene gene437 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02190 HW43_RS02195 HW43_02230 HW43_RS02195 460237 461115 + hypothetical protein gene gene438 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02195 HW43_RS02200 HW43_02235 HW43_RS02200 461379 462881 + glycine/betaine ABC transporter gene gene439 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02200 HW43_RS02205 HW43_24425 HW43_RS02205 462993 463082 + membrane protein gene gene440 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02205 HW43_RS02210 HW43_02245 HW43_RS02210 463058 464149 - two-component system sensor histidine kinase gene gene441 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02210 HW43_RS02215 HW43_02250 HW43_RS02215 464159 464827 - two-component system response regulator response regulator in two-component regulatory system with BasS gene gene442 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02215 HW43_RS02220 HW43_02255 HW43_RS02220 464824 466467 - metal dependent hydrolase gene gene443 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02220 HW43_RS02225 HW43_02260 HW43_RS02225 466571 467908 - arginine/agmatine antiporter gene gene444 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02225 HW43_RS02230 HW43_02265 HW43_RS02230 468045 468806 - transcriptional regulator regulates genes involved in arginine decarboxylase gene gene445 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02230 HW43_RS02235 HW43_02270 HW43_RS02235 469131 471401 - arginine decarboxylase biodegradative%3B catalyzes the formation of agmatine from arginine gene gene446 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02235 HW43_RS02240 HW43_02275 HW43_RS02240 471597 472505 - melibiose operon regulatory protein gene gene447 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02240 HW43_RS02245 HW43_24430 HW43_RS02245 472537 472698 + hypothetical protein gene gene448 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02245 HW43_RS02250 HW43_02280 HW43_RS02250 472788 474143 + alpha-galactosidase catalyses the hydrolysis of terminal non-reducing alpha-D-galactose residues in alpha-D-galactosides gene gene449 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02250 HW43_RS02255 HW43_02285 HW43_RS02255 474246 475667 + sugar:sodium symporter gene gene450 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02255 HW43_RS02260 HW43_02290 HW43_RS02260 475806 476435 - membrane protein gene gene451 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02260 HW43_RS02265 HW43_02295 HW43_RS02265 476558 478204 - fumarate hydratase class I%2C anaerobic catalyzes the formation of malate from fumerate gene gene452 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02265 HW43_RS02270 HW43_02300 HW43_RS02270 478282 479622 - anaerobic C4-dicarboxylate transporter DcuB functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate%3B similar to DcuA%3B DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate%2C malate%2C fumarate and succinate) transporters gene gene453 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02270 HW43_RS02275 HW43_24435 HW43_RS02275 480088 480216 + glutamate decarboxylase gene gene454 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02275 HW43_RS02280 HW43_02305 HW43_RS02280 480193 480912 - transcriptional regulator response regulator in two-component regulatory system with DcuS%3B phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration gene gene455 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02280 HW43_RS02285 HW43_02310 HW43_RS02285 480909 482540 - histidine kinase C4-dicarboxylate-sensing histidine kinase%3B part of two-component regulatory system with DcuR%3B regulates anaerobic fumarate respiration gene gene456 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02285 HW43_RS02290 HW43_02315 HW43_RS02290 482721 482951 + hypothetical protein gene gene457 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02290 HW43_RS02295 HW43_02320 HW43_RS02295 482963 483235 + hypothetical protein gene gene458 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02295 HW43_RS02300 HW43_02325 HW43_RS02300 483322 483537 + hypothetical protein gene gene459 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02300 HW43_RS02305 HW43_02330 HW43_RS02305 483552 483758 + hypothetical protein gene gene460 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02305 HW43_RS02310 HW43_24440 HW43_RS02310 483786 483959 + toxin of GhoTS toxin-antitoxin pair%3B membrane-lytic protein%3B stimulator of persister cell formation gene gene461 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02310 HW43_RS02315 HW43_02340 lysS lysS 484078 485595 - lysine--tRNA ligase heat inducible class II%3B LysRS2%3B catalyzes a two-step reaction%2C first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B in Methanosarcina barkeri%2C LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 gene gene462 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02315 HW43_RS02320 HW43_02345 HW43_RS02320 485832 487289 - dipeptide and tripeptide permease C gene gene463 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02320 HW43_RS02325 HW43_02350 HW43_RS02325 487348 489495 - lysine decarboxylase inducible constitutive%3B catalyzes the formation of cadaverine from lysine gene gene464 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02325 HW43_RS02330 HW43_02355 cadB cadB 489575 490909 - cadaverine/lysine antiporter antiporter protein responsible for lysine import and cadaverine export%3B member of the lysine-dependent acid resistance system 4 (AR4)%3B inner membrane protein gene gene465 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02330 HW43_RS02335 HW43_02360 HW43_RS02335 491274 492812 - transcriptional regulator regulates the cadBA operon gene gene466 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02335 HW43_RS02340 HW43_RS02340 HW43_RS02340 493099 493317 + hypothetical protein gene gene467 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02340 HW43_RS02345 HW43_02365 HW43_RS02345 493429 493504 - tRNA-Phe tRNA gene468 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02345 HW43_RS02350 HW43_02370 HW43_RS02350 493611 494186 - transcriptional regulator gene gene469 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02350 HW43_RS02355 HW43_02375 dipZ dipZ 494223 495920 - thiol:disulfide interchange protein two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm%3B DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm gene gene470 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02355 HW43_RS02360 HW43_02380 HW43_RS02360 495896 496234 - divalent-cation tolerance protein CutA copper binding protein required for copper tolerance%3B involved in resistance toward heavy metals gene gene471 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02360 HW43_RS02365 HW43_02385 HW43_RS02365 496350 497651 - anaerobic C4-dicarboxylate transporter DcuA functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate%3B similar to dcuB gene gene472 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02365 HW43_RS02370 HW43_02390 aspA aspA 497769 499205 - aspartate ammonia-lyase catalyzes the formation of fumarate from aspartate gene gene473 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02370 HW43_RS02375 HW43_02395 fxsA fxsA 499542 500018 + suppressor of F exclusion of phage T7 F exclusion of bacteriophage T7%3B overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7%3B interacts with the F plasmid-encoded PifA protein%3B inner membrane protein gene gene474 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02375 HW43_RS02380 HW43_02400 HW43_RS02380 500034 501290 - hypothetical protein uncharacterized member of the APC superfamily of amino acid transporters%3B unknown function gene gene475 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02380 HW43_RS02385 HW43_02405 groES groES 501566 501859 + molecular chaperone GroES 10 kDa chaperonin%3B Cpn10%3B GroES%3B forms homoheptameric ring%3B binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it%3B folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES%3B release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring gene gene476 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02385 HW43_RS02390 HW43_02410 groEL groEL 501903 503540 + chaperonin GroL 60 kDa chaperone family%3B promotes refolding of misfolded polypeptides especially under stressful conditions%3B forms two stacked rings of heptamers to form a barrel-shaped 14mer%3B ends can be capped by GroES%3B misfolded proteins enter the barrel where they are refolded when GroES binds%3B many bacteria have multiple copies of the groEL gene which are active under different environmental conditions%3B the B.japonicum protein in this cluster is expressed constitutively%3B in Rhodobacter%2C Corynebacterium and Rhizobium this protein is essential for growth gene gene477 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02390 HW43_RS02395 HW43_02415 HW43_RS02395 503678 504031 + DUF4156 domain-containing protein gene gene478 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02395 HW43_RS02400 HW43_02420 HW43_RS02400 504274 505254 + transposase gene gene479 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02400 HW43_RS02405 HW43_02425 HW43_RS02405 505503 506372 - hypothetical protein gene gene480 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02405 HW43_RS02410 HW43_02430 HW43_RS02410 506767 507795 - EF-P beta-lysylation protein EpmB gene gene481 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02410 HW43_RS02415 HW43_02435 HW43_RS02415 507837 508403 + elongation factor P gene gene482 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02415 HW43_RS02420 HW43_02440 HW43_RS02420 508455 508580 + entericidin A acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex gene gene483 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02420 HW43_RS02425 HW43_02445 HW43_RS02425 508691 508837 + entericidin B gene gene484 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02425 HW43_RS02430 HW43_02450 HW43_RS02430 509012 509329 + quaternary ammonium compound-resistance protein SugE member of the SMR family of proton-dependent drug efflux transporters%3B quaternary ammonium compound efflux pump%3B confers resistance to cetylpyridinium%2C cetyldimethylethyl ammonium and cetrimide cations gene gene485 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02430 HW43_RS02435 HW43_02455 HW43_RS02435 509326 509859 - hypothetical protein lipocalin%3B globomycin-sensitive outer membrane lipoprotein gene gene486 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02435 HW43_RS02440 HW43_02460 HW43_RS02440 509948 511081 - BlaEC family class C beta-lactamase gene gene487 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02440 HW43_RS02445 HW43_02465 HW43_RS02445 511144 511503 - fumarate reductase subunit D in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane gene gene488 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02445 HW43_RS02450 HW43_02470 HW43_RS02450 511514 511909 - fumarate reductase subunit C part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration%3B FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit%2C respectively%3B FrdCD are the membrane components which interact with quinone and are involved in electron transfer%3B the catalytic subunits are similar to succinate dehydrogenase SdhAB gene gene489 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02450 HW43_RS02455 HW43_02475 HW43_RS02455 511920 512654 - fumarate reductase iron-sulfur subunit part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration%3B FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit%2C respectively%3B FrdCD are the membrane components which interact with quinone and are involved in electron transfer%3B the catalytic subunits are similar to succinate dehydrogenase SdhAB gene gene490 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02455 HW43_RS02460 HW43_02480 HW43_RS02460 512647 514455 - fumarate reductase flavoprotein subunit part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration%3B FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit%2C respectively%3B FrdCD are the membrane components which interact with quinone and are involved in electron transfer%3B the catalytic subunits are similar to succinate dehydrogenase SdhAB gene gene491 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02460 HW43_RS02465 HW43_02485 HW43_RS02465 514780 515757 + elongation factor P--(R)-beta-lysine ligase poxA%3B regulates pyruvate oxidase poxB gene gene492 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02465 HW43_RS02470 HW43_02490 HW43_RS02470 515976 517478 + amino acid ABC transporter permease gene gene493 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02470 HW43_RS02475 HW43_02495 HW43_RS02475 517629 520952 - mechanosensitive channel protein gene gene494 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02475 HW43_RS02480 HW43_02500 psd psd 520974 521942 - phosphatidylserine decarboxylase proenzyme catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine gene gene495 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02480 HW43_RS02485 HW43_02505 HW43_RS02485 522039 523091 - GTPase RsgA EngC%3B RsgA%3B CpgA%3B circularly permuted GTPase%3B ribosome small subunit-dependent GTPase A%3B has the pattern G4-G1-G3 as opposed to other GTPases%3B interacts strongly with 30S ribosome which stimulates GTPase activity gene gene496 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02485 HW43_RS02490 HW43_02510 HW43_RS02490 523186 523731 + oligoribonuclease 3'-5' exoribonuclease specific for small oligoribonuclotides gene gene497 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02490 HW43_RS02495 HW43_02515 HW43_RS02495 523942 524017 + tRNA-Gly tRNA gene498 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02495 HW43_RS02500 HW43_02520 HW43_RS02500 524053 524128 + tRNA-Gly tRNA gene499 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02500 HW43_RS02505 HW43_02525 HW43_RS02505 524164 524239 + tRNA-Gly tRNA gene500 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02505 HW43_RS02510 HW43_02530 HW43_RS02510 524509 525648 - epoxyqueuosine reductase gene gene501 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02510 HW43_RS02515 HW43_02535 HW43_RS02515 525662 527194 + carbohydrate kinase gene gene502 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02515 HW43_RS02520 HW43_02540 HW43_RS02520 527166 527627 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaE needed for nucleoid integrity%3B possibly involved in cell wall synthesis gene gene503 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02520 HW43_RS02525 HW43_02545 HW43_RS02525 527646 528983 + N-acetylmuramoyl-L-alanine amidase gene gene504 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02525 HW43_RS02530 HW43_02550 HW43_RS02530 528993 530840 + DNA mismatch repair protein MutL gene gene505 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02530 HW43_RS02535 HW43_02555 miaA miaA 530833 531783 + tRNA dimethylallyltransferase IPP transferase%3B isopentenyltransferase%3B involved in tRNA modification%3B in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil%3B further tRNA modifications may occur%3B mutations in miaA result in defects in translation efficiency and fidelity gene gene506 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02535 HW43_RS02540 HW43_02560 hfq hfq 531869 532177 + RNA chaperone Hfq HF-I%2C host factor for RNA phage Q beta replication gene gene507 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02540 HW43_RS02545 HW43_02565 HW43_RS02545 532253 533533 + GTPase HflX involved in modulation of proteins HflK and HflC%3B part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein gene gene508 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02545 HW43_RS02550 HW43_02570 HW43_RS02550 533619 534878 + cell division protein FtsH with HflC inhibits proteolysis of lambda cII protein by FtsH gene gene509 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02550 HW43_RS02555 HW43_02575 HW43_RS02555 534881 535885 + modulator of FtsH protease HflC with HflK inhibits proteolysis of lambda cII protein by FtsH gene gene510 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02555 HW43_RS02560 HW43_02580 HW43_RS02560 535967 536164 + membrane protein gene gene511 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02560 HW43_RS02565 HW43_02585 HW43_RS02565 536268 537566 + adenylosuccinate synthetase catalyzes the formation of N6-(1%2C2%2C-dicarboxyethyl)-AMP from L-aspartate%2C inosine monophosphate and GTP in AMP biosynthesis gene gene512 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02565 HW43_RS02570 HW43_02590 HW43_RS02570 537771 538196 + transcriptional regulator negatively regulates the transcription of genes upregulated by nitrosative stress gene gene513 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02570 HW43_RS02575 HW43_02595 HW43_RS02575 538235 540676 + exoribonuclease R 3'-5'exoribonuclease that acts nonspecifically on poly(A)%2C poly(U) and ribosomal RNAs gene gene514 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02575 HW43_RS02580 HW43_02600 HW43_RS02580 540856 541587 + 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB Specifically methylates the ribose of guanosine 2251 in 23S rRNA gene gene515 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02580 HW43_RS02585 HW43_02605 HW43_RS02585 541714 542115 + hypothetical protein gene gene516 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02585 HW43_RS02590 HW43_02610 HW43_RS02590 542134 542832 + PspA/IM30 family protein gene gene517 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02590 HW43_RS02595 HW43_02615 HW43_RS02595 542883 543542 + hypothetical protein gene gene518 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02595 HW43_RS02600 HW43_02620 HW43_RS02600 543560 543958 + hypothetical protein gene gene519 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02600 HW43_RS02605 HW43_02625 HW43_RS02605 543968 544606 + membrane protein gene gene520 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02605 HW43_RS02610 HW43_02630 HW43_RS02610 544609 545772 + hypothetical protein gene gene521 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02610 HW43_RS02615 HW43_02635 HW43_RS02615 545856 547481 + isovaleryl CoA dehydrogenase catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA gene gene522 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02615 HW43_RS02620 HW43_02640 HW43_RS02620 547598 547873 - DUF1471 domain-containing protein gene gene523 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02620 HW43_RS02625 HW43_02645 HW43_RS02625 548022 548351 - lipoprotein BsmA in Escherichia coli%2C mutation of this gene affects biofilm maturation%2C stress response%2C and motility gene gene524 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02625 HW43_RS02630 HW43_02650 HW43_RS02630 548533 549282 + esterase YjfP%3B esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro%3B unknown function and substrate in vivo gene gene525 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02630 HW43_RS02635 HW43_02655 HW43_RS02635 549279 550034 - transcriptional regulator negative regulator of ulaG and ulaABCDEF gene gene526 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02635 HW43_RS02640 HW43_02660 HW43_RS02640 550142 551206 - L-ascorbate-6-phosphate lactonase UlaG gene gene527 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02640 HW43_RS02645 HW43_02665 HW43_RS02645 551561 552958 + PTS ascorbate transporter subunit IIC gene gene528 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02645 HW43_RS02650 HW43_02670 HW43_RS02650 552974 553279 + ascorbate-specific phosphotransferase enzyme IIB component involved in the phosphorylation and transport of sugars across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene529 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02650 HW43_RS02655 HW43_02675 HW43_RS02655 553289 553753 + ascorbate-specific phosphotransferase enzyme IIA component involved in the phosphorylation and transport of sugars across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene530 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02655 HW43_RS02660 HW43_02680 ulaD ulaD 553767 554417 + 3-keto-L-gulonate-6-phosphate decarboxylase ulaD catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization gene gene531 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02660 HW43_RS02665 HW43_02685 HW43_RS02665 554427 555281 + L-ribulose-5-phosphate 3-epimerase UlaE gene gene532 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02665 HW43_RS02670 HW43_02690 araD araD 555281 555967 + L-ribulose-5-phosphate 4-epimerase catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate%3B links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source gene gene533 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02670 HW43_RS02675 HW43_02695 HW43_RS02675 556096 556371 - hypothetical protein gene gene534 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02675 HW43_RS02680 HW43_24445 HW43_RS02680 556440 556550 + hypothetical protein gene gene535 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02680 HW43_RS02685 HW43_02700 rpsF rpsF 556698 557093 + 30S ribosomal protein S6 binds cooperatively with S18 to the S15-16S complex%2C allowing platform assembly to continue with S11 and S21 gene gene536 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02685 HW43_RS02690 HW43_02705 HW43_RS02690 557100 557414 + primosomal replication protein n binds single-stranded DNA at the primosome assembly site gene gene537 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02690 HW43_RS02695 HW43_02710 rpsR rpsR 557419 557646 + 30S ribosomal protein S18 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA%3B helps stabilize the platform of the 30S subunit gene gene538 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02695 HW43_RS02700 HW43_02715 rplI rplI 557688 558137 + 50S ribosomal protein L9 in Escherichia coli this protein is wrapped around the base of the L1 stalk gene gene539 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02700 HW43_RS02705 HW43_24450 HW43_RS02705 558208 559003 - hypothetical protein gene gene540 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02705 HW43_RS02710 HW43_02725 HW43_RS02710 559273 560550 - hexuronate transporter ExuT gene gene541 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02710 HW43_RS02715 HW43_02730 HW43_RS02715 560643 562715 - oxidoreductase gene gene542 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02715 HW43_RS02720 HW43_02735 HW43_RS02720 562712 564253 - hypothetical protein gene gene543 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02720 HW43_RS02725 HW43_02740 HW43_RS02725 564263 565039 - acyl-CoA hydratase gene gene544 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02725 HW43_RS02730 HW43_02745 HW43_RS02730 565049 565891 - hypothetical protein gene gene545 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02730 HW43_RS02735 HW43_02750 HW43_RS02735 565901 566692 - 3-ketoacyl-ACP reductase catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis gene gene546 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02735 HW43_RS02740 HW43_02755 HW43_RS02740 566904 567551 + TetR family transcriptional regulator gene gene547 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02740 HW43_RS02745 HW43_02760 HW43_RS02745 567535 568173 - OapA family protein gene gene548 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02745 HW43_RS02750 HW43_02765 HW43_RS02750 568391 569011 + FKBP-type peptidyl-prolyl cis-trans isomerase FKBP-type%3B rotamase%3B catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides gene gene549 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02750 HW43_RS02755 HW43_02770 HW43_RS02755 569320 570732 + D-serine/D-alanine/glycine transporter gene gene550 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02755 HW43_RS02760 HW43_02775 HW43_RS02760 570777 571439 - iron-sulfur cluster repair protein YtfE Involved in anaerobic NO protection and iron metabolism gene gene551 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02760 HW43_RS02765 HW43_02780 HW43_RS02765 571547 572512 - membrane protein gene gene552 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02765 HW43_RS02770 HW43_02785 HW43_RS02770 572621 573481 - quinone oxidoreductase gene gene553 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02770 HW43_RS02775 HW43_02790 HW43_RS02775 573480 573950 + HxlR family transcriptional regulator gene gene554 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02775 HW43_RS02780 HW43_02795 cpdB cpdB 574079 576022 - 3'-nucleotidase periplasmic enzyme%3B functions during ribonucleic acid degradation%3B 2'%2C3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate gene gene555 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02780 HW43_RS02785 HW43_02800 HW43_RS02785 576212 576952 + 3'(2')%2C5'-bisphosphate nucleotidase CysQ catalyzes the formation of AMP from adenosine-3'%2C5'-bisphosphate gene gene556 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02785 HW43_RS02790 HW43_02805 HW43_RS02790 576942 577499 - transcriptional regulator gene gene557 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02790 HW43_RS02795 HW43_02810 HW43_RS02795 577824 578030 + DUF1107 domain-containing protein gene gene558 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02795 HW43_RS02800 HW43_02815 HW43_RS02800 578092 579435 - hypothetical protein gene gene559 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02800 HW43_RS02805 HW43_02820 HW43_RS02805 579758 580396 - peptide methionine sulfoxide reductase MsrA this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form%3B provides protection against oxidative stress gene gene560 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02805 HW43_RS02810 HW43_24455 HW43_RS02810 580504 580632 + hypothetical protein gene gene561 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02810 HW43_RS02815 HW43_02825 HW43_RS02815 580602 582335 + translocation and assembly module TamA gene gene562 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02815 HW43_RS02820 HW43_02830 HW43_RS02820 582332 586111 + hypothetical protein gene gene563 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02820 HW43_RS02825 HW43_02835 HW43_RS02825 586114 586455 + gamma-glutamylcyclotransferase YtfP gene gene564 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02825 HW43_RS02830 HW43_02840 HW43_RS02830 586667 586918 + antitoxin ChpS part of the toxin-antitoxin ChpB-ChpS system gene gene565 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02830 HW43_RS02835 HW43_02845 HW43_RS02835 586912 587262 + toxin B toxin of the ChpB-ChpS toxin-antitoxin system gene gene566 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02835 HW43_RS02840 HW43_02850 HW43_RS02840 587342 587872 - inorganic pyrophosphatase catalyzes the hydrolysis of pyrophosphate to phosphate gene gene567 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02840 HW43_RS02845 HW43_02855 HW43_RS02845 588182 589138 + ABC transporter substrate-binding protein gene gene568 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02845 HW43_RS02850 HW43_02860 HW43_RS02850 589278 590780 + sugar ABC transporter ATP-binding protein gene gene569 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02850 HW43_RS02855 HW43_02865 HW43_RS02855 590794 591816 + sugar ABC transporter permease gene gene570 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02855 HW43_RS02860 HW43_02870 HW43_RS02860 591803 592798 + sugar ABC transporter permease membrane component of a putative sugar ABC transporter system gene gene571 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02860 HW43_RS02865 HW43_02875 HW43_RS02865 592831 593829 - fructose 1%2C6-bisphosphatase catalyzes the formation of D-fructose 6-phosphate from fructose-1%2C6-bisphosphate gene gene572 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02865 HW43_RS02870 HW43_02880 HW43_RS02870 594005 595378 + UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase ligates L-alanyl-gamma-D-glutamyl-meso-diaminopimelate to UDP-N-acetylmuramic acid for reincorporation into peptidoglycan gene gene573 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02870 HW43_RS02875 HW43_02885 HW43_RS02875 595529 596080 - ribosome-associated UPF0307 family protein gene gene574 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02875 HW43_RS02880 HW43_02890 pmbA pmbA 596174 597526 + metalloprotease PmbA protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD gene gene575 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02880 HW43_RS02885 HW43_02895 HW43_RS02885 597581 597967 + cytochrome B562 electron transport protein gene gene576 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02885 HW43_RS02890 HW43_02900 HW43_RS02890 598012 598476 - anaerobic ribonucleotide reductase-activating protein activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions gene gene577 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02890 HW43_RS02895 HW43_02905 HW43_RS02895 598636 600774 - ribonucleoside triphosphate reductase Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates gene gene578 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02895 HW43_RS02900 HW43_02910 HW43_RS02900 601168 602823 - trehalose-6-phosphate hydrolase gene gene579 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02900 HW43_RS02905 HW43_02915 HW43_RS02905 602873 604291 - PTS maltose transporter subunit IIBC phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene580 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02905 HW43_RS02910 HW43_02920 treR treR 604413 605360 - trehalose repressor regulates genes involved in trehalose metabolism%3B binds the intermediate trehalose-6-phosphate%3B binds a dimer%3B regulates treBC operon gene gene581 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02910 HW43_RS02915 HW43_02925 HW43_RS02915 605739 608435 + magnesium-translocating P-type ATPase P-type%3B involved in magnesium transport into the cytoplasm gene gene582 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02915 HW43_RS02920 HW43_02930 HW43_RS02920 608641 609027 - reactive intermediate/imine deaminase has endoribonuclease activity on mRNA gene gene583 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02920 HW43_RS02925 HW43_02935 HW43_RS02925 609100 609561 - aspartate carbamoyltransferase regulatory chain involved in the allosteric regulation of aspartate carbamoyltransferase gene gene584 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02925 HW43_RS02930 HW43_02940 HW43_RS02930 609574 610509 - aspartate carbamoyltransferase catalytic subunit gene gene585 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02930 HW43_RS02935 HW43_24460 HW43_RS02935 610513 610647 - pyrBI operon leader peptide gene gene586 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02935 HW43_RS02940 HW43_24465 HW43_RS02940 610777 610959 + hypothetical protein gene gene587 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02940 HW43_RS02945 HW43_02950 HW43_RS02945 610928 611323 - endoribonuclease L-PSP gene gene588 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02945 HW43_RS02950 HW43_02955 HW43_RS02950 611454 612194 - oxidoreductase gene gene589 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02950 HW43_RS02955 HW43_02960 HW43_RS02955 612237 612830 + TetR family transcriptional regulator gene gene590 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02955 HW43_RS02960 HW43_02970 HW43_RS02960 612975 613427 + hypothetical protein gene gene591 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02960 HW43_RS02965 HW43_02975 HW43_RS02965 613550 615066 + hypothetical protein gene gene592 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02965 HW43_RS02970 HW43_02980 HW43_RS02970 615138 616142 - ornithine carbamoyltransferase catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway gene gene593 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02970 HW43_RS02975 HW43_02985 HW43_RS02975 616304 616720 + regulator of ribonuclease activity B gene gene594 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02975 HW43_RS02980 HW43_02990 HW43_RS02980 616766 617269 - N-acetyltransferase gene gene595 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02980 HW43_RS02985 HW43_02995 HW43_RS02985 617462 618658 + hypothetical protein gene gene596 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02985 HW43_RS02990 HW43_03000 HW43_RS02990 618712 621567 - valine--tRNA ligase gene gene597 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02990 HW43_RS02995 HW43_03005 HW43_RS02995 621567 622010 - DNA polymerase III subunit chi binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB gene gene598 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS02995 HW43_RS03000 HW43_03010 HW43_RS03000 622364 623875 - cytosol aminopeptidase catalyzes the removal of N-terminal amino acids preferably from various peptides%3B a cyteinylglycinase%2C transcription regulator and site-specific recombination factor gene gene599 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03000 HW43_RS03005 HW43_03015 HW43_RS03005 624142 625242 + LPS export ABC transporter permease LptF with LptBGC is involved in lipopolysaccharide export gene gene600 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03005 HW43_RS03010 HW43_03020 HW43_RS03010 625242 626324 + LPS export ABC transporter permease LptG with LptABCF is involved in the transport of lipopolysaccharides gene gene601 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03010 HW43_RS03015 HW43_03025 HW43_RS03015 626443 627945 - hypothetical protein gene gene602 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03015 HW43_RS03020 HW43_03030 HW43_RS03020 628075 629094 - aldehyde reductase Ahr gene gene603 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03020 HW43_RS03025 HW43_03035 HW43_RS03025 629290 629374 + tRNA-Leu tRNA gene604 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03025 HW43_RS03030 HW43_03040 HW43_RS03030 629561 630805 + integrase gene gene605 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03030 HW43_RS03035 HW43_03045 HW43_RS03035 631304 632197 + hypothetical protein gene gene606 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03035 HW43_RS03040 HW43_03050 HW43_RS03040 632271 633521 + hypothetical protein gene gene607 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03040 HW43_RS03045 HW43_03055 HW43_RS03045 633518 634651 + hypothetical protein gene gene608 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03045 HW43_RS03050 HW43_03060 HW43_RS03050 635244 638024 + helicase SNF2 gene gene609 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03050 HW43_RS03055 HW43_03065 HW43_RS03055 638037 640487 + DEAD/DEAH box helicase gene gene610 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03055 HW43_RS03060 HW43_03070 HW43_RS03060 640487 641386 + hypothetical protein gene gene611 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03060 HW43_RS03065 HW43_03075 HW43_RS03065 641389 644532 + hypothetical protein gene gene612 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03065 HW43_RS03070 HW43_03080 HW43_RS03070 644519 645253 + hypothetical protein gene gene613 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03070 HW43_RS03075 HW43_03085 HW43_RS03075 645253 649767 + DEAD/DEAH box helicase gene gene614 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03075 HW43_RS03080 HW43_03090 HW43_RS03080 649764 650309 + hypothetical protein gene gene615 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03080 HW43_RS03085 HW43_03095 HW43_RS03085 650309 652480 + hypothetical protein gene gene616 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03085 HW43_RS03090 HW43_03100 HW43_RS03090 652743 653105 - 6-carboxy-5%2C6%2C7%2C8-tetrahydropterin synthase gene gene617 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03090 HW43_RS03095 HW43_03105 HW43_RS03095 653515 653790 + hypothetical protein gene gene618 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03095 HW43_RS03100 HW43_24470 HW43_RS03100 654249 654738 - transposase gene gene619 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03100 HW43_RS03105 HW43_03120 HW43_RS03105 654819 656327 - group II intron reverse transcriptase/maturase gene gene620 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03105 HW43_RS03110 HW43_24475 HW43_RS03110 656296 656721 + hypothetical protein gene gene621 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03110 HW43_RS03115 HW43_24480 HW43_RS03115 656636 657004 + hypothetical protein gene gene622 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03115 HW43_RS03120 HW43_24485 HW43_RS03120 656934 657359 - HTH-like domain protein gene gene623 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03120 HW43_RS03125 HW43_03130 HW43_RS03125 657490 658641 + transposase gene gene624 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03125 HW43_RS03130 HW43_24490 HW43_RS03130 658561 658911 - transposase gene gene625 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03130 HW43_RS03135 HW43_03135 HW43_RS03135 659058 659315 + hypothetical protein gene gene626 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03135 HW43_RS03140 HW43_03145 HW43_RS03140 659873 660640 - Fe(3+) dicitrate transport ATP-binding protein FecE gene gene627 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03140 HW43_RS03145 HW43_03150 fecD fecD 660641 661597 - Fe3+ dicitrate ABC transporter permease Ferric citrate binds FecA and is transported across the outer membrane while transmits a signal across the cytoplasmic membrane protein FecR. FecR transmits a signal across the membrane and activates the cytoplasmic FecI that directs the RNA polymerase to express the fecABCDE operon (which encodes the ferric citrate outer membrane receptor and the ferric citrate ABC transporter)%2C as well as fecIR. FecD is one of two (along with FecC) integral membrane protein components of the iron dicitrate ABC transporter. gene gene628 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03145 HW43_RS03150 HW43_03155 fecC fecC 661594 662592 - Fe(3+) dicitrate ABC transporter permease part of the FecBCDE citrate-dependent iron (III) transport system gene gene629 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03150 HW43_RS03155 HW43_03160 fecB fecB 662589 663491 - periplasmic-binding family protein part of the ABC transporter involved in the uptake of citrate-dependent Fe(3+) gene gene630 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03155 HW43_RS03160 HW43_03165 HW43_RS03160 663536 665860 - fe(3+) dicitrate transporter fecA gene gene631 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03160 HW43_RS03165 HW43_03170 HW43_RS03165 665947 666900 - protein FecR with FecA forms the FecAR signal transduction system%3B ferric citrate binds FecA and transmits a signal across the outer membrane to FecR. FecR transmits a signal across the cytoplasmic membrane and activates the sigma 70 protein FecI that directs the RNA polymerase to express the fecABCDE operon gene gene632 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03165 HW43_RS03170 HW43_03175 HW43_RS03170 666897 667418 - RNA polymerase sigma factor FecI Member of the extracytoplasmic function sigma factors which are active under specific conditions%3B binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription%3B this sigma factor regulates the genes for iron dicitrate transport gene gene633 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03170 HW43_RS03175 HW43_24495 HW43_RS03175 667710 667985 + Insertion element IS1 7 protein InsA gene gene634 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03175 HW43_RS03180 HW43_24500 HW43_RS03180 668181 668405 + transposase gene gene635 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03180 HW43_RS03185 HW43_03190 HW43_RS03185 669167 669424 + hypothetical protein gene gene636 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03185 HW43_RS03190 HW43_03195 HW43_RS03190 669587 669760 - hypothetical protein gene gene637 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03190 HW43_RS03195 HW43_03200 HW43_RS03195 670157 671515 + hypothetical protein gene gene638 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03195 HW43_RS03200 HW43_24505 HW43_RS03200 671754 671939 - protein encoded within IS gene gene639 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03200 HW43_RS03205 HW43_03210 HW43_RS03205 672267 672464 + hypothetical protein gene gene640 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03205 HW43_RS03210 HW43_03220 HW43_RS03210 673182 673400 - hypothetical protein gene gene641 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03210 HW43_RS03220 HW43_03225 HW43_RS03220 673746 674396 + HNH endonuclease gene gene642 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03220 HW43_RS03225 HW43_03230 HW43_RS03225 674404 675384 - hypothetical protein gene gene643 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03225 HW43_RS03230 HW43_03235 HW43_RS03230 675449 676555 - N-acetylneuraminic acid mutarotase gene gene644 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03230 HW43_RS03235 HW43_03240 HW43_RS03235 676575 677123 - porin gene gene645 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03235 HW43_RS03240 HW43_24515 HW43_RS03240 677662 677808 + hypothetical protein gene gene646 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03240 HW43_RS03245 HW43_24520 HW43_RS03245 678090 678335 - hypothetical protein gene gene647 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03245 HW43_RS03250 HW43_03250 HW43_RS03250 678745 679347 + type 1 fimbriae regulatory protein FimB gene gene648 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03250 HW43_RS03255 HW43_03255 HW43_RS03255 679824 680420 + type 1 fimbriae regulatory protein FimE inversion of on/off regulator of fimA gene gene649 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03255 HW43_RS03260 HW43_24525 HW43_RS03260 680571 680748 + hypothetical protein gene gene650 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03260 HW43_RS03265 HW43_03260 fimA fimA 680900 681454 + type-1 fimbrial protein subunit A gene gene651 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03265 HW43_RS03270 HW43_03265 HW43_RS03270 681561 682058 + fimbrin fimI gene gene652 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03270 HW43_RS03275 HW43_03270 HW43_RS03275 682095 682820 + molecular chaperone FimC gene gene653 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03275 HW43_RS03280 HW43_03275 HW43_RS03280 682887 685523 + outer membrane usher protein FimD gene gene654 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03280 HW43_RS03285 HW43_03280 HW43_RS03285 685533 686063 + fimbrial protein FimF gene gene655 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03285 HW43_RS03290 HW43_03285 HW43_RS03290 686076 686579 + protein FimG gene gene656 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03290 HW43_RS03295 HW43_03290 HW43_RS03295 686599 687501 + fimbrial protein FimH gene gene657 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03295 HW43_RS03300 HW43_03295 HW43_RS03300 687674 689017 - gluconate transporter gene gene658 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03300 HW43_RS03305 HW43_24530 HW43_RS03305 689175 689405 + hypothetical protein gene gene659 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03305 HW43_RS03310 HW43_03300 HW43_RS03310 689357 690541 + mannonate dehydratase catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate gene gene660 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03310 HW43_RS03315 HW43_03305 HW43_RS03315 690622 692082 + D-mannonate oxidoreductase gene gene661 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03315 HW43_RS03320 HW43_03310 HW43_RS03320 692104 692298 - hypothetical protein gene gene662 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03320 HW43_RS03325 HW43_03315 HW43_RS03325 692297 693070 + transcriptional regulator regulates the expression of uxuBA gene gene663 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03325 HW43_RS03330 HW43_03320 HW43_RS03330 693211 694041 - hypothetical protein gene gene664 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03330 HW43_RS03335 HW43_24535 HW43_RS03335 693992 694132 - hypothetical protein gene gene665 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03335 HW43_RS03340 HW43_24540 HW43_RS03340 694614 694748 + hypothetical protein gene gene666 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03340 HW43_RS03345 HW43_03325 iraD iraD 694714 695106 + anti-adapter protein IraD inhibitor of RssB activity in response to DNA damage%3B blocks degradation of stationary phase sigma factor RpoS gene gene667 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03345 HW43_RS03350 HW43_03330 HW43_RS03350 695099 696010 - transcriptional regulator gene gene668 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03350 HW43_RS03355 HW43_03335 HW43_RS03355 696075 697247 - isoaspartyl dipeptidase gene gene669 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03355 HW43_RS03360 HW43_03340 HW43_RS03360 697260 697721 - hypothetical protein gene gene670 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03360 HW43_RS03365 HW43_03345 HW43_RS03365 697718 698401 - nucleoside recognition pore and gate family inner membrane transporter gene gene671 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03365 HW43_RS03370 HW43_03350 HW43_RS03370 698651 699205 + RNA 2'-phosphotransferase in yeast cells this enzyme removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate%3B functions in tRNA splicing%3B the function and substrate of bacterial enzymes in organisms that do not perform splicing is unknown gene gene672 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03370 HW43_RS03375 HW43_03355 HW43_RS03375 699218 700396 - hypothetical protein gene gene673 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03375 HW43_RS03380 HW43_03360 HW43_RS03380 700464 701324 - hypothetical protein gene gene674 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03380 HW43_RS03385 HW43_03365 HW43_RS03385 701389 701646 - hypothetical protein gene gene675 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03385 HW43_RS03390 HW43_03370 HW43_RS03390 701643 702410 - hypothetical protein gene gene676 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03390 HW43_RS03395 HW43_03375 HW43_RS03395 702420 703571 - 2-hydroxyglutaryl-CoA dehydratase gene gene677 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03395 HW43_RS03400 HW43_03380 HW43_RS03400 703687 704967 - membrane protein gene gene678 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03400 HW43_RS03405 HW43_03385 HW43_RS03405 705008 706240 - multidrug transporter is involved in resistance to acriflavine%2C chloramphenicol%2C norfloxacin%2C ethidium bromide and TPP gene gene679 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03405 HW43_RS03410 HW43_03390 HW43_RS03410 706538 706813 + transposase gene gene680 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03410 HW43_RS03415 HW43_24545 HW43_RS03415 706858 707025 + transposase gene gene681 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03415 HW43_RS03420 HW43_24550 HW43_RS03420 707026 707235 + transposase gene gene682 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03420 HW43_RS03425 HW43_03400 HW43_RS03425 707434 707721 + membrane protein gene gene683 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03425 HW43_RS03430 HW43_03405 HW43_RS03430 707708 708010 + hypothetical protein gene gene684 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03430 HW43_RS03435 HW43_03410 HW43_RS03435 708044 709000 - GTP-binding protein gene gene685 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03435 HW43_RS03440 HW43_03415 HW43_RS03440 709011 709214 - hypothetical protein gene gene686 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03440 HW43_RS03445 HW43_03420 HW43_RS03445 709264 711414 - hypothetical protein gene gene687 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03445 HW43_RS03450 HW43_24555 HW43_RS03450 711459 711632 - hypothetical protein gene gene688 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03450 HW43_RS03455 HW43_03425 HW43_RS03455 711791 713464 + methyl-accepting chemotaxis protein serine sensor receptor gene gene689 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03455 HW43_RS03460 HW43_03430 HW43_RS03460 713513 714874 - L-galactonate transporter gene gene690 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03460 HW43_RS03465 HW43_03435 HW43_RS03465 715091 716005 - transcriptional regulator gene gene691 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03465 HW43_RS03470 HW43_03440 HW43_RS03470 716144 717166 + galactonate oxidoreductase gene gene692 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03470 HW43_RS03475 HW43_03445 HW43_RS03475 717307 719598 - phosphoglycerol transferase I catalyzes the transfer of phosphoglycerol to the glucan backbone gene gene693 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03475 HW43_RS03480 HW43_03450 HW43_RS03480 719852 720343 - hypothetical protein gene gene694 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03480 HW43_RS03485 HW43_03455 HW43_RS03485 720395 721132 - DNA replication protein DnaC acts to load the DnaB helicase onto the initiation site during DNA replication gene gene695 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03485 HW43_RS03490 HW43_03460 HW43_RS03490 721135 721674 - primosomal protein 1 This protein is required for primosome-dependent normal DNA replication%3B it is also involved in inducing stable DNA replication during SOS response. It forms%2C in concert with dnaB protein and other prepriming proteins dnaC%2C N%2C N'%2C N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' gene gene696 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03490 HW43_RS03495 HW43_03465 HW43_RS03495 721781 722254 - hypothetical protein gene gene697 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03495 HW43_RS03500 HW43_03470 HW43_RS03500 722245 723015 - membrane protein gene gene698 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03500 HW43_RS03505 HW43_03475 HW43_RS03505 723633 724358 + transcriptional regulator gene gene699 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03505 HW43_RS03510 HW43_03480 HW43_RS03510 724316 724993 + transcriptional activator protein BglJ regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin gene gene700 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03510 HW43_RS03515 HW43_03485 HW43_RS03515 725031 725819 - ferric iron reductase involved in ferric hydroximate transport gene gene701 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03515 HW43_RS03520 HW43_03490 HW43_RS03520 725921 726196 + hypothetical protein gene gene702 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03520 HW43_RS03525 HW43_03495 HW43_RS03525 726235 726321 - tRNA-Leu tRNA gene703 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03525 HW43_RS03530 HW43_03500 HW43_RS03530 726356 726442 - tRNA-Leu tRNA gene704 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03530 HW43_RS03535 HW43_03505 HW43_RS03535 726471 726557 - tRNA-Leu tRNA gene705 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03535 HW43_RS03540 HW43_24560 HW43_RS03540 726623 726752 - hypothetical protein gene gene706 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03540 HW43_RS03545 HW43_03510 rsmC rsmC 726866 727897 - ribosomal RNA small subunit methyltransferase C 16S rRNA M2G1207 methyltransferase%3B one of many enzymes that modify bases of the ribosomal RNA%3B this enzyme methylates the G at position 1207 of the small ribosomal subunit gene gene707 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03545 HW43_RS03550 HW43_03515 HW43_RS03550 728000 728413 + DNA polymerase III subunit psi with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB gene gene708 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03550 HW43_RS03555 HW43_03520 rimI rimI 728382 728828 + ribosomal-protein-alanine acetyltransferase alanine acetyltransferase that specifically acetylates ribosomal protein S18 gene gene709 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03555 HW43_RS03560 HW43_03525 HW43_RS03560 728843 729520 + dUMP phosphatase manganese-dependent 5'-nucleotidase%3B specific for 5'-UMP%2C 5'-dUMP%2C and 5'-dTMP%3B member of haloacid dehalogenase (HAD)-like hydrolase superfamily gene gene710 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03560 HW43_RS03565 HW43_03530 prfC prfC 729611 731200 + peptide chain release factor 3 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred%3B GDP/GTP-binding protein gene gene711 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03565 HW43_RS03570 HW43_03535 HW43_RS03570 731593 732198 + osmotically-inducible protein Y gene gene712 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03570 HW43_RS03575 HW43_24565 HW43_RS03575 732325 732486 + hypothetical protein gene gene713 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03575 HW43_RS03580 HW43_03545 HW43_RS03580 732608 733681 + patatin gene gene714 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03580 HW43_RS03585 HW43_03550 HW43_RS03585 733678 734460 + deoxyribonuclease gene gene715 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03585 HW43_RS03590 HW43_03555 HW43_RS03590 734674 735537 - glycine radical enzyme activase gene gene716 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03590 HW43_RS03595 HW43_03560 HW43_RS03595 735509 737059 - hypothetical protein gene gene717 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03595 HW43_RS03600 HW43_24570 HW43_RS03600 737111 737212 + hypothetical protein gene gene718 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03600 HW43_RS03605 HW43_03565 HW43_RS03605 737317 738096 + deoxyribose-phosphate aldolase catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate gene gene719 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03605 HW43_RS03610 HW43_03570 HW43_RS03610 738223 739545 + thymidine phosphorylase gene gene720 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03610 HW43_RS03615 HW43_03575 HW43_RS03615 739597 740820 + phosphopentomutase gene gene721 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03615 HW43_RS03620 HW43_03580 deoD deoD 740900 741619 + purine nucleoside phosphorylase catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate gene gene722 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03620 HW43_RS03625 HW43_24575 HW43_RS03625 741894 742043 - hypothetical protein gene gene723 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03625 HW43_RS03630 HW43_03590 lplA lplA 742075 743091 - lipoate-protein ligase A Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins gene gene724 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03630 HW43_RS03635 HW43_03595 HW43_RS03635 743119 743763 - protein Smp gene gene725 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03635 HW43_RS03640 HW43_03600 serB serB 743869 744837 + phosphoserine phosphatase catalyzes the formation of serine from O-phosphoserine gene gene726 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03640 HW43_RS03645 HW43_03605 HW43_RS03645 744886 746268 + DNA repair protein RadA Sms%3B stabilizes the strand-invasion intermediate during the DNA repair%3B involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents gene gene727 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03645 HW43_RS03650 HW43_03610 HW43_RS03650 746289 747521 + transcriptional regulator catalyzes the formation of NAD(+) from nicotinamide ribonucleotide%3B catalyzes the formation of nicotinamide mononucleotide from nicotinamide riboside%3B also has a regulatory function gene gene728 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03650 HW43_RS03655 HW43_24580 HW43_RS03655 747572 747721 + transcriptional regulator gene gene729 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03655 HW43_RS03660 HW43_03615 HW43_RS03660 747828 749495 - energy-dependent translational throttle protein EttA ChvD%3B in Agrobacterium tumefaciens%2C mutations in both Walker boxes were found to affect virulence gene gene730 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03660 HW43_RS03665 HW43_03620 HW43_RS03665 749706 751643 + murein transglycosylase catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan gene gene731 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03665 HW43_RS03670 HW43_03625 HW43_RS03670 751733 752059 + Trp operon repressor When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription gene gene732 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03670 HW43_RS03675 HW43_03630 yjjX yjjX 752101 752613 - non-canonical purine NTP phosphatase pyrophosphatase%3B has activity against dUTP and dITP%3B the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226%3B in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms%3B in Escherichia coli overexpression of this gene leads to resistance to an HMP analog gene gene733 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03675 HW43_RS03680 HW43_03635 HW43_RS03680 752665 753312 + phosphoglycerate mutase GpmB catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate gene gene734 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03680 HW43_RS03685 HW43_03640 HW43_RS03685 753309 754178 - right origin-binding protein AraC family%3B binds to the right arm of the replication origin oriC gene gene735 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03685 HW43_RS03690 HW43_03645 HW43_RS03690 754389 754862 + protein CreA gene gene736 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03690 HW43_RS03695 HW43_03650 HW43_RS03695 754875 755564 + two-component system response regulator response regulator in two-component regulatory system with CreC%3B CreB protein is phosphorylated by sensor protein phospho-CreC%3B involved in catabolic regulation gene gene737 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03695 HW43_RS03700 HW43_03655 HW43_RS03700 755564 756988 + two-component system sensor histidine kinase part of a two-component regulatory system with CreB or PhoB%3B involved in catabolic regulation gene gene738 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03700 HW43_RS03705 HW43_03660 HW43_RS03705 757046 758398 + membrane protein gene gene739 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03705 HW43_RS03710 HW43_03665 HW43_RS03710 758458 759174 - two-component system response regulator gene gene740 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03710 HW43_RS03715 HW43_24585 HW43_RS03715 759270 759410 + hypothetical protein gene gene741 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03715 HW43_RS03720 HW43_03670 HW43_RS03720 759810 760496 + RNA methyltransferase member of the SPOUT superfamily of methyltransferases gene gene742 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03720 HW43_RS03725 HW43_24590 thrL thrL 760710 760775 + thr operon leader peptide involved in threonine biosynthesis%3B controls the expression of the thrLABC operon gene gene743 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03725 HW43_RS03730 HW43_03675 thrA thrA 760856 763318 + bifunctional aspartokinase I/homoserine dehydrogenase I multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine%3B functions in a number of amino acid biosynthetic pathways gene gene744 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03730 HW43_RS03735 HW43_03680 HW43_RS03735 763320 764252 + homoserine kinase catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate gene gene745 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03735 HW43_RS03740 HW43_03685 HW43_RS03740 764253 765539 + threonine synthase gene gene746 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03740 HW43_RS03745 HW43_24595 HW43_RS03745 765607 765756 + hypothetical protein gene gene747 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03745 HW43_RS03750 HW43_03690 HW43_RS03750 765753 766049 + hypothetical protein gene gene748 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03750 HW43_RS03755 HW43_03695 HW43_RS03755 766309 767289 + transposase gene gene749 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03755 HW43_RS03760 HW43_03700 HW43_RS03760 767481 768257 - hypothetical protein gene gene750 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03760 HW43_RS03765 HW43_03705 HW43_RS03765 768327 769757 - transporter gene gene751 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03765 HW43_RS03770 HW43_03710 HW43_RS03770 770036 770989 + transaldolase 1 gene gene752 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03770 HW43_RS03775 HW43_03715 mogA mogA 771104 771691 + molybdenum cofactor biosynthesis protein MogA forms a trimer%3B related to eukaryotic protein gephyrin%3B functions during molybdenum cofactor biosynthesis gene gene753 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03775 HW43_RS03780 HW43_03720 HW43_RS03780 771726 772292 - succinate-acetate/proton symporter SatP gene gene754 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03780 HW43_RS03785 HW43_03725 HW43_RS03785 772441 773154 - hypothetical protein gene gene755 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03785 HW43_RS03790 HW43_03730 HW43_RS03790 773180 773584 - hypothetical protein gene gene756 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03790 HW43_RS03795 HW43_03735 dnaK dnaK 773961 775877 + molecular chaperone DnaK heat shock protein 70%3B assists in folding of nascent polypeptide chains%3B refolding of misfolded proteins%3B utilizes ATPase activity to help fold%3B co-chaperones are DnaJ and GrpE%3B multiple copies in some bacteria gene gene757 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03795 HW43_RS03800 HW43_03740 HW43_RS03800 775966 777096 + molecular chaperone DnaJ chaperone Hsp40%3B co-chaperone with DnaK%3B Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins%2C also in an autonomous%2C dnaK-independent fashion gene gene758 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03800 HW43_RS03805 HW43_03745 HW43_RS03805 777200 777352 - protein HokC gene gene759 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03805 HW43_RS03810 HW43_03750 nhaA nhaA 777938 779104 + Na+/H+ antiporter NhaA exports sodium by using the electrochemical proton gradient to allow protons into the cell%3B functions in adaptation to high salinity and alkaline pH%3B activity increases at higher pH%3B downregulated at acidic pH gene gene760 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03810 HW43_RS03815 HW43_03755 nhaR nhaR 779170 780069 + transcriptional regulator Na+/H+ antiporter regulatory protein%3B activates the genes nhaA and osmC gene gene761 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03815 HW43_RS03820 HW43_03760 HW43_RS03820 780108 780533 - hypothetical protein gene gene762 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03820 HW43_RS03825 HW43_03765 HW43_RS03825 780848 781066 - hypothetical protein gene gene763 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03825 HW43_RS03830 HW43_03770 HW43_RS03830 781079 782224 - fimbrial usher protein gene gene764 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03830 HW43_RS03835 HW43_03775 HW43_RS03835 782657 783778 - secretion protein EspX gene gene765 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03835 HW43_RS03840 HW43_03780 rpsT rpsT 784560 784823 - 30S ribosomal protein S20 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase gene gene766 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03840 HW43_RS03845 HW43_24600 HW43_RS03845 784926 785144 + hypothetical protein gene gene767 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03845 HW43_RS03850 HW43_03785 HW43_RS03850 785152 786093 + bifunctional riboflavin kinase/FMN adenylyltransferase gene gene768 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03850 HW43_RS03855 HW43_03790 ileS ileS 786136 788952 + isoleucine--tRNA ligase IleRS%3B catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile)%3B since isoleucine and other amino acids such as valine are similar%2C there are additional editing function in this enzyme%3B one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile)%3B there are two active sites%2C one for aminoacylation and one for editing%3B class-I aminoacyl-tRNA synthetase family type 1 subfamily%3B some organisms carry two different copies of this enzyme gene gene769 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03855 HW43_RS03860 HW43_03795 lspA lspA 788952 789446 + lipoprotein signal peptidase lipoprotein signal peptidase%3B integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis gene gene770 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03860 HW43_RS03865 HW43_03800 HW43_RS03865 789534 789983 + peptidyl-prolyl cis-trans isomerase rotamase%3B accelerates isomerization of the peptidyl prolyl bond%2C involved in the folding of proteases gene gene771 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03865 HW43_RS03870 HW43_03805 ispH ispH 789985 790935 + 4-hydroxy-3-methylbut-2-enyl diphosphate reductase catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)%3B functions in the nonmevalonate isoprenoid biosynthesis pathway gene gene772 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03870 HW43_RS03875 HW43_03810 HW43_RS03875 791001 791915 + non-specific ribonucleoside hydrolase RihC catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides gene gene773 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03875 HW43_RS03880 HW43_03815 HW43_RS03880 792082 792903 + 4-hydroxy-tetrahydrodipicolinate reductase catalyzes the reduction of 2%2C3-dihydrodipicolinate to 2%2C3%2C4%2C5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis gene gene774 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03880 HW43_RS03885 HW43_24605 HW43_RS03885 792945 793112 - hypothetical protein gene gene775 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03885 HW43_RS03890 HW43_24610 HW43_RS03890 793146 793241 - hypothetical protein gene gene776 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03890 HW43_RS03895 HW43_03825 HW43_RS03895 793359 794507 + carbamoyl-phosphate synthase small chain catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways%3B forms an octamer composed of four CarAB dimers gene gene777 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03895 HW43_RS03900 HW43_03830 carB carB 794525 797746 + carbamoyl phosphate synthase large subunit four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate%3B CarB is responsible for the amidotransferase activity gene gene778 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03900 HW43_RS03905 HW43_24615 HW43_RS03905 797777 797971 - hypothetical protein gene gene779 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03905 HW43_RS03910 HW43_03835 HW43_RS03910 798006 798401 + transcriptional regulator regulator of carnitine metabolism%3B induces the caiTABCDE and fixABCX operons gene gene780 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03910 HW43_RS03915 HW43_03840 HW43_RS03915 798487 799077 - carnitine operon protein CaiE involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities gene gene781 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03915 HW43_RS03920 HW43_03845 HW43_RS03920 799083 799868 - carnitinyl-CoA dehydratase catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA gene gene782 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03920 HW43_RS03925 HW43_03850 caiC caiC 799977 801530 - crotonobetaine/carnitine-CoA ligase gene gene783 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03925 HW43_RS03930 HW43_03855 HW43_RS03930 801604 802821 - L-carnitine CoA-transferase catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA%2C also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine gene gene784 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03930 HW43_RS03935 HW43_03860 HW43_RS03935 802950 804092 - crotonobetainyl-CoA dehydrogenase catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA gene gene785 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03935 HW43_RS03940 HW43_03865 HW43_RS03940 804123 804470 - BCCT family transporter gene gene786 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03940 HW43_RS03945 HW43_03870 HW43_RS03945 804827 805009 - hypothetical protein gene gene787 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03945 HW43_RS03950 HW43_03875 HW43_RS03950 805216 805497 - hypothetical protein gene gene788 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03950 HW43_RS03955 HW43_03880 HW43_RS03955 805753 806295 - terminase gene gene789 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03955 HW43_RS03960 HW43_03885 HW43_RS03960 806502 806915 - hypothetical protein gene gene790 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03960 HW43_RS03965 HW43_03890 HW43_RS03965 806928 807263 - phage capsid protein gene gene791 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03965 HW43_RS03970 HW43_03895 HW43_RS03970 807275 808330 - head protein gene gene792 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03970 HW43_RS03975 HW43_03900 HW43_RS03975 808330 808536 - hypothetical protein gene gene793 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03975 HW43_RS03980 HW43_03905 HW43_RS03980 808791 809039 - hypothetical protein gene gene794 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03980 HW43_RS03985 HW43_03910 HW43_RS03985 809029 809277 - hypothetical protein gene gene795 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03985 HW43_RS03990 HW43_03915 HW43_RS03990 809631 811763 - hypothetical protein gene gene796 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03990 HW43_RS03995 HW43_03920 HW43_RS03995 811760 812074 - hypothetical protein gene gene797 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS03995 HW43_RS04000 HW43_03925 HW43_RS04000 812080 812307 - hypothetical protein gene gene798 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04000 HW43_RS04005 HW43_03930 HW43_RS04005 812300 812536 - hypothetical protein gene gene799 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04005 HW43_RS04010 HW43_03935 HW43_RS04010 812526 813086 - Ash family protein gene gene800 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04010 HW43_RS04015 HW43_24620 HW43_RS04015 813219 813410 + repressor gene gene801 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04015 HW43_RS04020 HW43_24625 HW43_RS04020 813675 813863 - DNA-binding protein gene gene802 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04020 HW43_RS04025 HW43_03940 HW43_RS04025 814238 815467 - integrase gene gene803 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04025 HW43_RS04030 HW43_24630 HW43_RS04030 815632 816774 - L-carnitine:gamma-butyrobetaine antiporter catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism gene gene804 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04030 HW43_RS04035 HW43_03950 HW43_RS04035 817248 818018 + protein FixA required for anaerobic carnitine reduction%2C may act to transfer electrons to crotonobetaine reductase gene gene805 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04035 HW43_RS04040 HW43_03955 HW43_RS04040 818033 818974 + protein FixB gene gene806 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04040 HW43_RS04045 HW43_03960 HW43_RS04045 819025 820311 + oxidoreductase FixC FAD/NAD(P)-binding domain%3B possibly part of an electron transfer system required for anaerobic carnitine reduction gene gene807 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04045 HW43_RS04050 HW43_03965 HW43_RS04050 820308 820595 + ferredoxin-like protein FixX gene gene808 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04050 HW43_RS04055 HW43_03970 HW43_RS04055 820654 821985 + metabolite transporter gene gene809 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04055 HW43_RS04060 HW43_03975 HW43_RS04060 822093 822623 + glutathione-regulated potassium-efflux system ancillary protein KefF Required for full activity of KefC%2C a potassium-proton antiporter gene gene810 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04060 HW43_RS04065 HW43_03980 HW43_RS04065 822616 824478 + glutathione-regulated potassium-efflux system protein KefC transport system that facilitates potassium-efflux gene gene811 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04065 HW43_RS04070 HW43_03985 folA folA 824670 825149 + dihydrofolate reductase catalyzes the reduction of dihydrofolate to tetrahydrofolate gene gene812 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04070 HW43_RS04075 HW43_03990 apaH apaH 825227 826069 - diadenosine tetraphosphatase hydrolyzes P(1)%2CP(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP gene gene813 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04075 HW43_RS04080 HW43_03995 apaG apaG 826076 826453 - protein ApaG protein associated with Co2+ and Mg2+ efflux gene gene814 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04080 HW43_RS04085 HW43_04000 ksgA ksgA 826456 827277 - ribosomal RNA small subunit methyltransferase A in Escherichia coli this enzyme catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA%3B mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin%3B members of this protein family have secondary functions gene gene815 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04085 HW43_RS04090 HW43_04005 pdxA pdxA 827274 828263 - 4-hydroxythreonine-4-phosphate dehydrogenase catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) gene gene816 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04090 HW43_RS04095 HW43_04010 HW43_RS04095 828263 829549 - chaperone SurA Chaperone involved in the folding of extracytoplasmic proteins%2C especially OmpA%2C OmpF and LamB gene gene817 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04095 HW43_RS04100 HW43_04015 HW43_RS04100 829602 831956 - LPS-assembly protein LptD is involved in outer membrane permeability gene gene818 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04100 HW43_RS04105 HW43_04020 djlA djlA 832211 833026 + dnaJ-like protein DjlA functions as a co-chaperone with DnaK%3B involved in regulation of colanic acid capsule%3B inner membrane protein%3B dimerized via transmembrane domain%3B J-like domain is cytoplasmic and can functionally substitute for DnaJ%3B stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system gene gene819 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04105 HW43_RS04110 HW43_04025 HW43_RS04110 833143 833802 - ribosomal large subunit pseudouridine synthase A catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs gene gene820 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04110 HW43_RS04115 HW43_04030 HW43_RS04115 833814 836720 - RNA polymerase-associated protein RapA transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP%2C when it is trapped or immobilized on tightly supercoiled DNA gene gene821 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04115 HW43_RS04120 HW43_04035 HW43_RS04120 836885 839236 - DNA polymerase II Has polymerase%2C DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C gene gene822 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04120 HW43_RS04125 HW43_04040 araD araD 839311 840006 - L-ribulose-5-phosphate 4-epimerase catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate%3B links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source gene gene823 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04125 HW43_RS04130 HW43_04045 HW43_RS04130 840206 841708 - L-arabinose isomerase catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism gene gene824 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04130 HW43_RS04135 HW43_04050 HW43_RS04135 841719 843419 - ribulokinase catalyzes the phosphorylation of ribulose to ribulose 5-phosphate gene gene825 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04135 HW43_RS04140 HW43_04055 HW43_RS04140 843758 844636 + arabinose operon regulatory protein positive and negative regulator%3B regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose gene gene826 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04140 HW43_RS04145 HW43_04060 HW43_RS04145 844722 845486 + membrane protein gene gene827 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04145 HW43_RS04150 HW43_04065 thiQ thiQ 845600 846298 - thiamine ABC transporter ATP-binding protein with TbpA and ThiP is part of the thiamine and TPP transport system gene gene828 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04150 HW43_RS04155 HW43_04070 thiP thiP 846282 847892 - thiamine ABC transporter permease permease%3B with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell%3B repressed in presence of exogenous thiamine gene gene829 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04155 HW43_RS04160 HW43_04075 tbpA tbpA 847868 848851 - thiamine ABC transporter substrate-binding protein part of the thiamine and TPP transport system tbpA-thiPQ gene gene830 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04160 HW43_RS04165 HW43_04080 HW43_RS04165 849015 850670 - transcriptional regulator activates sgrS under glucose-phosphate stress conditions gene gene831 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04165 HW43_RS04170 HW43_04085 HW43_RS04170 850759 850890 + inhibitor of glucose uptake gene gene832 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04170 HW43_RS04175 HW43_04090 HW43_RS04175 850992 852170 + sugar MFS transporter gene gene833 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04175 HW43_RS04180 HW43_04095 leuD leuD 852219 852824 - 3-isopropylmalate dehydratase small subunit catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis%3B forms a heterodimer of LeuC/D gene gene834 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04180 HW43_RS04185 HW43_04100 HW43_RS04185 852835 854235 - 3-isopropylmalate dehydratase large subunit dehydratase component%2C catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate gene gene835 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04185 HW43_RS04190 HW43_04105 HW43_RS04190 854238 855329 - 3-isopropylmalate dehydrogenase gene gene836 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04190 HW43_RS04195 HW43_04110 HW43_RS04195 855329 856900 - 2-isopropylmalate synthase gene gene837 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04195 HW43_RS04200 HW43_24635 HW43_RS04200 856993 857079 - leu operon leader peptide involved in attenuation control of the leuABCD operon in leucine biosynthesis gene gene838 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04200 HW43_RS04205 HW43_04115 leuO leuO 857739 858683 + leucine transcriptional activator activator for leuABCD operon%3B member of LysR family of transcriptional activators gene gene839 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04205 HW43_RS04210 HW43_04120 HW43_RS04210 859001 860725 + acetolactate synthase catalyzes the formation of 2-acetolactate from pyruvate%2C leucine sensitive gene gene840 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04210 HW43_RS04215 HW43_04125 ilvH ilvH 860728 861219 + acetolactate synthase with IlvI catalyzes the formation of 2-acetolactate from pyruvate%2C the small subunit is required for full activity and valine sensitivity%3B E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates%2C valine sensitivity and affinity for cofactors%3B also known as acetolactate synthase 3 small subunit gene gene841 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04215 HW43_RS04220 HW43_24640 HW43_RS04220 861231 861317 + fruR/shl operon leader peptide gene gene842 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04220 HW43_RS04225 HW43_04130 HW43_RS04225 861399 862403 + catabolite repressor/activator binds D-fructose as an inducer%3B involved in regulation of operons for central pathways of carbon metabolism gene gene843 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04225 HW43_RS04230 HW43_04135 HW43_RS04230 863005 863463 + transcriptional regulator MraZ MraZ%3B UPF0040%3B crystal structure shows similarity to AbrB gene gene844 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04230 HW43_RS04235 HW43_04140 HW43_RS04235 863465 864406 + ribosomal RNA small subunit methyltransferase H gene gene845 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04235 HW43_RS04240 HW43_04145 HW43_RS04240 864403 864768 + cell division protein FtsL membrane bound cell division protein at septum containing leucine zipper motif gene gene846 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04240 HW43_RS04245 HW43_04150 HW43_RS04245 864784 866550 + peptidoglycan synthase FtsI penicillin-binding protein 3%3B transpeptidase involved in septal peptidoglycan synthesis gene gene847 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04245 HW43_RS04250 HW43_04155 murE murE 866537 868024 + UDP-N-acetylmuramoylalanyl-D-glutamate--2%2C 6-diaminopimelate ligase involved in cell wall formation%3B peptidoglycan synthesis%3B cytoplasmic enzyme%3B catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate gene gene848 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04250 HW43_RS04255 HW43_04160 murF murF 868021 869379 + UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase gene gene849 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04255 HW43_RS04260 HW43_04165 mraY mraY 869373 870455 + phospho-N-acetylmuramoyl-pentapeptide transferase First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan gene gene850 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04260 HW43_RS04265 HW43_04170 murD murD 870458 871774 + UDP-N-acetylmuramoylalanine--D-glutamate ligase UDP-N-acetylmuramoylalanine--D-glutamate ligase%3B involved in peptidoglycan biosynthesis%3B cytoplasmic%3B catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation gene gene851 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04265 HW43_RS04270 HW43_04175 HW43_RS04270 871774 873018 + lipid II flippase FtsW gene gene852 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04270 HW43_RS04275 HW43_04180 murG murG 873015 874082 + UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase N-acetylglucosaminyl transferase%3B UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase%3B involved in cell wall formation%3B inner membrane-associated%3B last step of peptidoglycan synthesis gene gene853 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04275 HW43_RS04280 HW43_04185 HW43_RS04280 874136 875611 + UDP-N-acetylmuramate--L-alanine ligase gene gene854 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04280 HW43_RS04285 HW43_04190 ddl ddl 875604 876524 + D-alanine--D-alanine ligase B D-alanine--D-alanine ligase%3B DdlA%3B DdlB%3B cytoplasmic%3B catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis%3B there are two forms of this enzyme in Escherichia coli gene gene855 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04285 HW43_RS04290 HW43_04195 HW43_RS04290 876526 877356 + cell division protein FtsQ involved in septum formation gene gene856 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04290 HW43_RS04295 HW43_04200 ftsA ftsA 877353 878615 + cell division protein FtsA ATP-binding involved in recruitment of FtsK to Z ring%3B essential cell division protein%3B colocalizes with FtsZ through direct interaction to the septal ring structure%3B structurally similar to eukaryotic actin%3B binds directly to the cell membrane gene gene857 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04295 HW43_RS04300 HW43_04205 HW43_RS04300 878676 879827 + cell division protein FtsZ GTPase%3B similar structure to tubulin%3B forms ring-shaped polymers at the site of cell division%3B other proteins such as FtsA%2C ZipA%2C and ZapA%2C interact with and regulate FtsZ function gene gene858 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04300 HW43_RS04305 HW43_04210 lpxC lpxC 879928 880845 + UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase zinc-dependent%3B catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis gene gene859 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04305 HW43_RS04310 HW43_04215 HW43_RS04310 881076 881588 + secretion monitor secM translational pause allows for the initiation of secA translation gene gene860 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04310 HW43_RS04315 HW43_04220 secA secA 881650 884355 + protein translocase subunit SecA functions in protein export%3B can interact with acidic membrane phospholipids and the SecYEG protein complex%3B binds to preproteins%3B binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein%3B ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane%3B additional proteins SecD/F/YajC aid SecA recycling%3B exists in an equilibrium between monomers and dimers%3B may possibly form higher order oligomers%3B proteins in this cluster correspond SecA1%3B SecA2 is not essential and seems to play a role in secretion of a subset of proteins gene gene861 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04315 HW43_RS04320 HW43_04225 HW43_RS04320 884415 884804 + nucleoside triphosphate pyrophosphohydrolase gene gene862 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04320 HW43_RS04325 HW43_24645 HW43_RS04325 884819 884953 - hypothetical protein gene gene863 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04325 HW43_RS04330 HW43_04230 HW43_RS04330 884904 885101 - DNA gyrase inhibitor YacG inhibits supercoiling by DNA gyrase by binding to the GyrB subunit gene gene864 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04330 HW43_RS04335 HW43_04235 HW43_RS04335 885111 885854 - cell division protein ZapD gene gene865 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04335 HW43_RS04340 HW43_04240 coaE coaE 885854 886474 - dephospho-CoA kinase catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A%3B involved in coenzyme A biosynthesis gene gene866 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04340 HW43_RS04345 HW43_04245 HW43_RS04345 886699 887742 + GMP reductase catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate gene gene867 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04345 HW43_RS04350 HW43_04250 HW43_RS04350 887777 888979 - type IV pilin biogenesis protein gene gene868 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04350 HW43_RS04355 HW43_04255 HW43_RS04355 888969 890354 - hypothetical protein gene gene869 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04355 HW43_RS04360 HW43_04260 HW43_RS04360 890364 890768 - prepilin peptidase dependent protein gene gene870 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04360 HW43_RS04365 HW43_04265 HW43_RS04365 890876 892372 + resolvase gene gene871 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04365 HW43_RS04370 HW43_04270 HW43_RS04370 892490 893923 + hypothetical protein gene gene872 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04370 HW43_RS04375 HW43_04275 HW43_RS04375 894907 895947 + hypothetical protein gene gene873 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04375 HW43_RS04380 HW43_04280 HW43_RS04380 895991 896350 + hypothetical protein gene gene874 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04380 HW43_RS04385 HW43_04285 HW43_RS04385 896900 897457 + DNA invertase Pin gene gene875 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04385 HW43_RS04390 HW43_04290 HW43_RS04390 897595 898698 - hypothetical protein gene gene876 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04390 HW43_RS04395 HW43_04295 HW43_RS04395 898698 899975 - hypothetical protein gene gene877 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04395 HW43_RS04400 HW43_24650 HW43_RS04400 900424 900648 + hypothetical protein gene gene878 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04400 HW43_RS04405 HW43_04305 HW43_RS04405 900605 901498 - nicotinate-nucleotide pyrophosphorylase [carboxylating] catalyzes the formation of pyridine-2%2C3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide gene gene879 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04405 HW43_RS04410 HW43_04310 HW43_RS04410 901586 902137 + 1%2C6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD gene gene880 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04410 HW43_RS04415 HW43_04315 HW43_RS04415 902134 902988 + protein AmpE involved in regulation of beta-lactamase%3B putative signaling protein gene gene881 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04415 HW43_RS04420 HW43_04320 HW43_RS04420 903031 904401 - aromatic amino acid transporter gene gene882 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04420 HW43_RS04425 HW43_04325 pdhR pdhR 904945 905709 + pyruvate dehydrogenase complex repressor activates lctPRD operon%3B autoregulates itself through repression of pdhR-aceEF-lpdA operon%3B regulates pyruvate dehydrogenase complex gene gene883 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04425 HW43_RS04430 HW43_04330 aceE aceE 905870 908533 + pyruvate dehydrogenase E1 component E1 component%3B part of pyruvate dehydrogenase%3B forms a complex with DlaT and LpdC gene gene884 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04430 HW43_RS04435 HW43_04335 aceF aceF 908548 910440 + dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex E2 component of pyruvate dehydrogenase multienzyme complex%3B in Escherichia coli AceF contains three N-terminal lipoyl domains gene gene885 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04435 HW43_RS04440 HW43_04340 HW43_RS04440 910765 912189 + dihydrolipoyl dehydrogenase E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex%3B catalyzes the oxidation of dihydrolipoamide to lipoamide gene gene886 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04440 HW43_RS04445 HW43_04345 HW43_RS04445 912260 914017 - hypothetical protein gene gene887 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04445 HW43_RS04450 HW43_04350 HW43_RS04450 914372 916969 + aconitate hydratase 2 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate gene gene888 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04450 HW43_RS04455 HW43_04355 HW43_RS04455 917144 917506 + hypothetical protein gene gene889 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04455 HW43_RS04460 HW43_04360 HW43_RS04460 917544 918338 - S-adenosylmethionine decarboxylase proenzyme S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine gene gene890 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04460 HW43_RS04465 HW43_04365 HW43_RS04465 918354 919220 - polyamine aminopropyltransferase gene gene891 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04465 HW43_RS04470 HW43_04370 HW43_RS04470 919326 919673 - PulS_OutS family protein gene gene892 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04470 HW43_RS04475 HW43_04375 HW43_RS04475 919839 921389 + multicopper oxidase laccase%3B copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification gene gene893 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04475 HW43_RS04480 HW43_04380 HW43_RS04480 921436 923826 - glucose dehydrogenase quinoprotein glucose dehydrogenase%3B catalyzes the formation of D-glucono-1%2C5-lactone from D-glucose and ubiquinone gene gene894 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04480 HW43_RS04485 HW43_04385 HW43_RS04485 924032 924568 + hypoxanthine phosphoribosyltransferase catalyzes the formation of inosine monophosphate from hypoxanthine and 5-phospho-alpha-D-ribose 1-diphosphate gene gene895 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04485 HW43_RS04490 HW43_04390 HW43_RS04490 924609 925271 - carbonic anhydrase catalyzes the interconversion of bicarbonate and carbon dioxide gene gene896 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04490 HW43_RS04495 HW43_04395 HW43_RS04495 925380 926306 + ABC transporter ATPase gene gene897 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04495 HW43_RS04500 HW43_04400 HW43_RS04500 926303 927073 + inner membrane transport permease YadH gene gene898 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04500 HW43_RS04505 HW43_04405 HW43_RS04505 927178 927618 + PTS sugar transporter subunit IIA gene gene899 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04505 HW43_RS04510 HW43_04410 HW43_RS04510 927682 928911 + hypothetical protein gene gene900 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04510 HW43_RS04515 HW43_04415 HW43_RS04515 928915 929295 - aspartate 1-decarboxylase gene gene901 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04515 HW43_RS04520 HW43_04420 HW43_RS04520 929569 930471 + transposase gene gene902 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04520 HW43_RS04525 HW43_04425 panC panC 930545 931396 - pantothenate synthetase catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine gene gene903 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04525 HW43_RS04530 HW43_04430 panB panB 931408 932202 - 3-methyl-2-oxobutanoate hydroxymethyltransferase catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5%2C10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate gene gene904 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04530 HW43_RS04535 HW43_04435 HW43_RS04535 932315 933589 - fimbrial protein gene gene905 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04535 HW43_RS04540 HW43_04440 HW43_RS04540 933642 934238 - fimbrial protein gene gene906 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04540 HW43_RS04545 HW43_04445 HW43_RS04545 934265 934867 - fimbrial protein gene gene907 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04545 HW43_RS04550 HW43_04450 HW43_RS04550 934882 935451 - fimbrial protein StaD gene gene908 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04550 HW43_RS04555 HW43_04455 HW43_RS04555 935468 938068 - fimbrial protein similar to the fimbrial usher protein PapC gene gene909 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04555 HW43_RS04560 HW43_04460 ecpD ecpD 938103 938843 - molecular chaperone EcpD gene gene910 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04560 HW43_RS04565 HW43_04465 HW43_RS04565 938948 939532 - fimbrial-like adhesin protein gene gene911 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04565 HW43_RS04570 HW43_04470 HW43_RS04570 939902 940381 - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7%2C8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7%2C8-dihydropteridine and ATP gene gene912 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04570 HW43_RS04575 HW43_04475 pcnB pcnB 940378 941742 - poly(A) polymerase I Polymerase that creates the 3' poly(A) tail found in some mRNA's gene gene913 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04575 HW43_RS04580 HW43_04480 HW43_RS04580 941835 942731 - glutamyl-Q tRNA(Asp) ligase this tRNA synthetase lacks the tRNA anticodon interaction domain%3B instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4%2C5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp%3B the modified tRNA does not bind elongation factor Tu gene gene914 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04580 HW43_RS04585 HW43_04485 dksA dksA 942798 943253 - RNA polymerase-binding transcription factor DksA gene gene915 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04585 HW43_RS04590 HW43_04490 HW43_RS04590 943431 944135 - sugar fermentation stimulation protein A gene gene916 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04590 HW43_RS04595 HW43_04495 HW43_RS04595 944150 944680 - RNA 2'%2C3'-cyclic phosphodiesterase catalyzes the ligation and cleavage of of 2'-5' linkages in RNA gene gene917 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04595 HW43_RS04600 HW43_04500 HW43_RS04600 944709 947183 + RNA helicase similar in sequence to the ATP-dependent RNA helicase HrpA gene gene918 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04600 HW43_RS04605 HW43_24655 HW43_RS04605 947186 947392 + hypothetical protein gene gene919 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04605 HW43_RS04610 HW43_04510 mrcB mrcB 947379 949913 + penicillin-binding protein 1B penicillin-binding protein 1b%3B contains transglycosylase and transpeptidase activity%3B major enzyme for peptidoglycan biosynthesis in Escherichia coli%3B transmembrane protein%3B forms dimers%3B three variants%2C one of which may be a degradation product%2C while the other appears to result from an alternative initiation site%2C are found within the cell gene gene920 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04610 HW43_RS04615 HW43_04515 HW43_RS04615 950133 952376 + ferrichrome-iron receptor involved with the transport of ferrichrome across the outer membrane%3B binds the ferrichrome-iron ligand and interacts with the TonB protein gene gene921 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04615 HW43_RS04620 HW43_04520 HW43_RS04620 952427 953224 + iron(3+)-hydroxamate import ATP-binding protein FhuC part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter gene gene922 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04620 HW43_RS04625 HW43_04525 HW43_RS04625 953224 954114 + iron-hydroxamate transporter substrate-binding subunit Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter%3B binds to all hydroxamate siderophores gene gene923 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04625 HW43_RS04630 HW43_04530 HW43_RS04630 954111 956093 + iron-hydroxamate transporter permease subunit gene gene924 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04630 HW43_RS04635 HW43_04535 HW43_RS04635 956128 957408 - glutamate-1-semialdehyde 2%2C1-aminomutase Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway gene gene925 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04635 HW43_RS04640 HW43_04540 HW43_RS04640 957633 959054 + chloride channel protein Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation gene gene926 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04640 HW43_RS04645 HW43_04545 HW43_RS04645 959136 959480 + iron-sulfur cluster insertion protein ErpA essential respiratory protein A%3B may be involved in the transfer of iron-sulfur clusters%3B essential for growth using oxygen or alternate electron acceptors gene gene927 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04645 HW43_RS04650 HW43_04550 HW43_RS04650 959527 960150 - hypothetical protein gene gene928 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04650 HW43_RS04655 HW43_04555 HW43_RS04655 960188 960988 - vitamin B12-binding protein solute binding component of the vitamin B12 transport system BtuCDF gene gene929 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04655 HW43_RS04660 HW43_04560 HW43_RS04660 960981 961679 - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine gene gene930 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04660 HW43_RS04665 HW43_04565 dgt dgt 961763 963280 + deoxyguanosinetriphosphate triphosphohydrolase forms a homotetramer%3B requires magnesium for activity%3B catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate gene gene931 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04665 HW43_RS04670 HW43_04570 HW43_RS04670 963410 964834 + serine endoprotease protease Do%3B required at high temperature%3B degrades damaged proteins gene gene932 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04670 HW43_RS04675 HW43_04575 HW43_RS04675 965017 966147 + transcriptional regulator regulates the expression of the operons for the enzymes involved in galactarate%2C glucarate and glycerate utilization gene gene933 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04675 HW43_RS04680 HW43_04580 HW43_RS04680 966236 966622 - hypothetical protein gene gene934 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04680 HW43_RS04685 HW43_04585 dapD dapD 966934 967758 - 2%2C3%2C4%2C5-tetrahydropyridine-2%2C6-dicarboxylate N-succinyltransferase catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway gene gene935 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04685 HW43_RS04690 HW43_04590 HW43_RS04690 967789 970461 - PII uridylyl-transferase catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein gene gene936 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04690 HW43_RS04695 HW43_04595 HW43_RS04695 970523 971317 - methionine aminopeptidase catalyzes the removal of N-terminal amino acids from peptides and arylamides%3B generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn%2C Fe%2C or Mn gene gene937 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04695 HW43_RS04700 HW43_04600 HW43_RS04700 971685 972410 + 30S ribosomal protein S2 gene gene938 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04700 HW43_RS04705 HW43_04605 tsf tsf 972668 973519 + elongation factor Ts EF-Ts%3B functions during elongation stage of protein translation%3B forms a dimer%3B associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu gene gene939 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04705 HW43_RS04710 HW43_04610 HW43_RS04710 973666 974391 + uridylate kinase gene gene940 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04710 HW43_RS04715 HW43_04615 frr frr 974683 975240 + ribosome-recycling factor Rrf%3B Frr%3B ribosome-recycling factor%3B release factor 4%3B RF4%3B recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G%3B A GTPase-dependent process results in release of 50S from 70S%3B inhibited by release factor RF-1%3B essential for viability%3B structurally similar to tRNAs gene gene941 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04715 HW43_RS04720 HW43_04620 HW43_RS04720 975332 976528 + 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzes the formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose-5-phosphate gene gene942 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04720 HW43_RS04725 HW43_04625 HW43_RS04725 976717 977475 + UDP pyrophosphate synthase catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate gene gene943 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04725 HW43_RS04730 HW43_04630 cdsA cdsA 977488 978345 + phosphatidate cytidylyltransferase catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate gene gene944 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04730 HW43_RS04735 HW43_04635 HW43_RS04735 978357 979709 + inner membrane zinc RIP metalloprotease%3B RpoE activator%2C by degrading RseA%3B cleaved signal peptide endoprotease catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response gene gene945 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04735 HW43_RS04740 HW43_04640 HW43_RS04740 979739 982171 + outer membrane protein assembly factor BamA part of a complex with YfgL%2C YfiO%2C and NlpB involved in outer membrane protein biosynthesis%3B involved in the assembly of outer membrane proteins gene gene946 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04740 HW43_RS04745 HW43_04645 HW43_RS04745 982293 982778 + chaperone protein Skp gene gene947 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04745 HW43_RS04750 HW43_04650 lpxD lpxD 982782 983807 + UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis gene gene948 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04750 HW43_RS04755 HW43_04655 HW43_RS04755 983912 984367 + 3-hydroxyacyl-ACP dehydratase gene gene949 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04755 HW43_RS04760 HW43_04660 HW43_RS04760 984371 985159 + acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis gene gene950 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04760 HW43_RS04765 HW43_04665 lpxB lpxB 985159 986307 + lipid-A-disaccharide synthase catalyzes the formation of lipid A disaccharide from UDP-2%2C3-diacylglucosamine and 2%2C3-diacylglucosamine-1-phosphate%2C lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM gene gene951 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04765 HW43_RS04770 HW43_04670 rnhB rnhB 986304 986900 + ribonuclease HII RNH2%3B RNase HII%3B binds manganese%3B endonuclease which specifically degrades the RNA of RNA-DNA hybrids gene gene952 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04770 HW43_RS04775 HW43_04675 dnaE dnaE 986937 990419 + DNA polymerase III subunit alpha catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time%3B main replicative polymerase gene gene953 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04775 HW43_RS04780 HW43_04680 HW43_RS04780 990432 991391 + acetyl-CoA carboxylase carboxyltransferase subunit alpha catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%3B forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits%3B one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein gene gene954 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04780 HW43_RS04785 HW43_04685 HW43_RS04785 991490 993631 + lysine decarboxylase constitutive constitutive%3B catalyzes the formation of cadaverine from lysine gene gene955 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04785 HW43_RS04790 HW43_04690 HW43_RS04790 993688 994077 + lyase gene gene956 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04790 HW43_RS04795 HW43_04695 tilS tilS 994142 995440 + tRNA(Ile)-lysidine synthetase Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU%3B ATP-dependent%3B responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase gene gene957 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04795 HW43_RS04800 HW43_04700 HW43_RS04800 995489 995749 - Rho-binding antiterminator Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination gene gene958 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04800 HW43_RS04805 HW43_04705 HW43_RS04805 995736 995936 - hypothetical protein gene gene959 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04805 HW43_RS04810 HW43_04710 HW43_RS04810 996102 996647 + hypothetical protein gene gene960 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04810 HW43_RS04815 HW43_04715 HW43_RS04815 996644 997066 + hypothetical protein gene gene961 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04815 HW43_RS04820 HW43_04720 HW43_RS04820 997080 997790 + lipoprotein involved with copper homeostasis and adhesion gene gene962 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04820 HW43_RS04825 HW43_04725 HW43_RS04825 998040 999020 + transposase gene gene963 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04825 HW43_RS04830 HW43_04730 HW43_RS04830 999223 1000047 - hypothetical protein gene gene964 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04830 HW43_RS04835 HW43_04735 HW43_RS04835 1000100 1001818 - prolyl-tRNA synthetase catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) gene gene965 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04835 HW43_RS04840 HW43_04740 HW43_RS04840 1001929 1002636 - tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA gene gene966 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04840 HW43_RS04845 HW43_04745 rcsF rcsF 1002633 1003037 - hypothetical protein gene gene967 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04845 HW43_RS04850 HW43_04750 metQ metQ 1003155 1003970 - D-methionine-binding lipoprotein MetQ gene gene968 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04850 HW43_RS04855 HW43_04755 HW43_RS04855 1004010 1004663 - methionine ABC transporter part of the MetNIQ methionine uptake system gene gene969 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04855 HW43_RS04860 HW43_04760 metN metN 1004656 1005687 - methionine import ATP-binding protein MetN part of the metNIQ transport system for methionine gene gene970 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04860 HW43_RS04865 HW43_04765 HW43_RS04865 1005875 1006447 + D%2CD-heptose 1%2C7-bisphosphate phosphatase Converts the D-glycero-beta-D-manno-heptose 1%2C7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate gene gene971 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04865 HW43_RS04870 HW43_04770 HW43_RS04870 1006809 1008364 + 16S ribosomal RNA rRNA gene972 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04870 HW43_RS04875 HW43_04775 HW43_RS04875 1008421 1008497 + tRNA-Ile tRNA gene973 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04875 HW43_RS04880 HW43_04780 HW43_RS04880 1008540 1008615 + tRNA-Ala tRNA gene974 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04880 HW43_RS04885 HW43_04785 HW43_RS04885 1008790 1011720 + 23S ribosomal RNA rRNA gene975 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04885 HW43_RS04890 HW43_04790 HW43_RS04890 1011797 1011912 + 5S ribosomal RNA rRNA gene976 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04890 HW43_RS04895 HW43_04795 HW43_RS04895 1011967 1012043 + tRNA-Asp tRNA gene977 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04895 HW43_RS04900 HW43_04800 dkgB dkgB 1012206 1013009 + 2%2C5-diketo-D-gluconic acid reductase catalyzes the reduction of 2%2C5-diketo-D-gluconic acid to 2-keto-L-gulonic acid gene gene978 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04900 HW43_RS04905 HW43_04805 HW43_RS04905 1013006 1013920 - LysR family transcriptional regulator gene gene979 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04905 HW43_RS04910 HW43_04810 HW43_RS04910 1014161 1014961 + endo/exonuclease/phosphatase gene gene980 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04910 HW43_RS04915 HW43_04815 HW43_RS04915 1015039 1015809 + S-adenosyl-L-methionine (SAM)-dependent methyltransferase PhcB gene gene981 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04915 HW43_RS04920 HW43_04820 mltD mltD 1015857 1017215 - murein transglycosylase catalyzes the cleavage of the beta-1%2C4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues%3B may play a role in recycling muropeptides during cell division and/or cell elongation%3B in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall gene gene982 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04920 HW43_RS04925 HW43_04825 HW43_RS04925 1017287 1018042 - hydroxyacylglutathione hydrolase catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione%3B plays an important role in cellular detoxification using glutathione gene gene983 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04925 HW43_RS04930 HW43_04830 HW43_RS04930 1018076 1018798 + hypothetical protein gene gene984 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04930 HW43_RS04935 HW43_04835 HW43_RS04935 1018795 1019262 - ribonuclease HI%2C degrades RNA of DNA-RNA hybrids gene gene985 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04935 HW43_RS04940 HW43_04840 HW43_RS04940 1019318 1020058 + DNA polymerase III subunit epsilon 3'-5' exonuclease of DNA polymerase III gene gene986 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04940 HW43_RS04945 HW43_04845 HW43_RS04945 1020191 1020267 + tRNA-Asp tRNA gene987 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04945 HW43_RS04950 HW43_04855 HW43_RS04950 1020594 1021379 + aminopeptidase gene gene988 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04950 HW43_RS04955 HW43_04860 HW43_RS04955 1021516 1021995 - hypothetical protein gene gene989 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04955 HW43_RS04960 HW43_04865 HW43_RS04960 1022005 1022919 - membrane protein gene gene990 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04960 HW43_RS04965 HW43_04870 HW43_RS04965 1022963 1023445 - type VI secretion system protein gene gene991 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04965 HW43_RS04970 HW43_04875 HW43_RS04970 1023469 1024821 - membrane protein gene gene992 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04970 HW43_RS04975 HW43_04880 HW43_RS04975 1024832 1026115 - hypothetical protein gene gene993 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04975 HW43_RS04980 HW43_04885 HW43_RS04980 1026271 1028760 + hypothetical protein gene gene994 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04980 HW43_RS04985 HW43_04890 HW43_RS04985 1028729 1029919 + hypothetical protein gene gene995 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04985 HW43_RS04990 HW43_04895 HW43_RS04990 1029903 1030385 + hypothetical protein gene gene996 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04990 HW43_RS04995 HW43_24660 HW43_RS04995 1030525 1030713 + transposase gene gene997 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS04995 HW43_RS05000 HW43_04905 HW43_RS05000 1030982 1032025 + hypothetical protein gene gene998 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05000 HW43_RS05005 HW43_04910 HW43_RS05005 1032067 1032837 - hypothetical protein NAD(P)-binding gene gene999 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05005 HW43_RS05010 HW43_04915 HW43_RS05010 1033018 1033464 + hypothetical protein inactivates vertebrate C-type lysozyme gene gene1000 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05010 HW43_RS05015 HW43_04920 fadE fadE 1033507 1035951 - acyl-CoA dehydrogenase functions in fatty acid oxidation%3B converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA gene gene1001 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05015 HW43_RS05020 HW43_04925 gmhA gmhA 1036191 1036769 + phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate gene gene1002 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05020 HW43_RS05025 HW43_04930 HW43_RS05025 1036975 1037742 + glutamine amidotransferase gene gene1003 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05025 HW43_RS05030 HW43_04935 HW43_RS05030 1037713 1038453 - transpeptidase gene gene1004 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05030 HW43_RS05035 HW43_04940 HW43_RS05035 1038609 1038887 - mRNA interferase YafQ gene gene1005 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05035 HW43_RS05040 HW43_04945 HW43_RS05040 1038890 1039150 - DNA-damage-inducible protein J DNA-damage-inducible protein J%3B antitoxin of YafQ-DinJ toxin-antitoxin system gene gene1006 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05040 HW43_RS05045 HW43_04950 HW43_RS05045 1039360 1040109 + endopeptidase gene gene1007 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05045 HW43_RS05050 HW43_04955 HW43_RS05050 1040166 1040522 - DNA repair protein HhH-GPD gene gene1008 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05050 HW43_RS05055 HW43_04960 HW43_RS05055 1040515 1040793 - toxin HicA gene gene1009 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05055 HW43_RS05060 HW43_04965 HW43_RS05060 1040898 1042637 - flagellar biosynthesis protein FlhA gene gene1010 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05060 HW43_RS05065 HW43_04970 HW43_RS05065 1042597 1043367 + hypothetical protein gene gene1011 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05065 HW43_RS05070 HW43_04975 HW43_RS05070 1043438 1044493 + DNA polymerase IV involved in translesion DNA polymerization with beta clamp of polymerase III%3B belongs to Y family of polymerases%3B does not contain proofreading function gene gene1012 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05070 HW43_RS05075 HW43_04980 HW43_RS05075 1044568 1044942 + acyltransferase gene gene1013 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05075 HW43_RS05080 HW43_04985 HW43_RS05080 1045188 1046327 + hypothetical protein mutations in this gene result in a compromised ability for drug-inducible mexXY expression%3B expression is inducible by the same ribosome-targeting agents that induce mexXY gene gene1014 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05080 HW43_RS05085 HW43_04990 prfH prfH 1046324 1046938 + peptide chain release factor similar to release factor 1 and 2 gene gene1015 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05085 HW43_RS05090 HW43_04995 HW43_RS05090 1046995 1048452 - aminoacyl-histidine dipeptidase catalyzes the hydrolysis of Xaa-His dipeptides gene gene1016 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05090 HW43_RS05095 HW43_05000 HW43_RS05095 1048713 1049171 + xanthine phosphoribosyltransferase catalyzes the conversion of guanine%2C xanthine and%2C to a lesser extent%2C hypoxanthine to GMP%2C XMP and IMP%2C respectively gene gene1017 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05095 HW43_RS05100 HW43_05005 frsA frsA 1049263 1050507 + esterase forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc%3B FrsA may promote fermentation gene gene1018 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05100 HW43_RS05105 HW43_05010 HW43_RS05105 1050565 1050966 + sigma factor-binding protein Crl involved in the expression of csgBA which is involved in curli formation%3B interacts with sigmaS gene gene1019 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05105 HW43_RS05110 HW43_05015 HW43_RS05110 1051005 1052060 - outer membrane pore protein E gene gene1020 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05110 HW43_RS05115 HW43_05020 HW43_RS05115 1052348 1053451 + glutamate 5-kinase gene gene1021 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05115 HW43_RS05120 HW43_05025 HW43_RS05120 1053463 1054716 + gamma-glutamyl phosphate reductase gene gene1022 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05120 HW43_RS05125 HW43_05030 HW43_RS05125 1054831 1054906 + tRNA-Thr tRNA gene1023 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05125 HW43_RS05130 HW43_05035 HW43_RS05130 1055033 1055443 - hypothetical protein gene gene1024 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05130 HW43_RS05135 HW43_05040 HW43_RS05135 1055422 1056378 - hypothetical protein gene gene1025 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05135 HW43_RS05140 HW43_05045 HW43_RS05140 1056388 1058586 - xanthine dehydrogenase gene gene1026 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05140 HW43_RS05145 HW43_05050 HW43_RS05145 1058583 1059539 - oxidoreductase gene gene1027 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05145 HW43_RS05150 HW43_05055 HW43_RS05150 1059536 1060225 - aldehyde oxidoreductase gene gene1028 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05150 HW43_RS05155 HW43_05060 HW43_RS05155 1060643 1061257 + hypothetical protein gene gene1029 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05155 HW43_RS05160 HW43_24665 HW43_RS05160 1061505 1061834 - ferredoxin gene gene1030 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05160 HW43_RS05165 HW43_05070 HW43_RS05165 1062147 1062857 - hypothetical protein gene gene1031 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05165 HW43_RS05170 HW43_05075 HW43_RS05170 1062826 1064469 - hypothetical protein gene gene1032 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05170 HW43_RS05175 HW43_05080 HW43_RS05175 1064459 1066984 - hypothetical protein gene gene1033 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05175 HW43_RS05180 HW43_05085 HW43_RS05180 1067010 1067678 - fimbrial chaperone EcpB gene gene1034 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05180 HW43_RS05185 HW43_05090 HW43_RS05185 1067736 1068323 - common pilus major fimbrillin subunit EcpA gene gene1035 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05185 HW43_RS05190 HW43_05095 HW43_RS05190 1068398 1068940 - LuxR family transcriptional regulator gene gene1036 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05190 HW43_RS05195 HW43_05100 HW43_RS05195 1069763 1069990 + hypothetical protein gene gene1037 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05195 HW43_RS05200 HW43_05105 rpmJ rpmJ 1070025 1070165 - 50S ribosomal protein L36 smallest protein in the large subunit%3B similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc%3B the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion%3B the proteins in this group do not have the motif gene gene1038 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05200 HW43_RS05205 HW43_05110 HW43_RS05205 1070165 1070428 - 50S ribosomal protein L31 type B gene gene1039 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05205 HW43_RS05210 HW43_05115 HW43_RS05210 1070791 1070892 - hypothetical protein gene gene1040 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05210 HW43_RS05215 HW43_05120 HW43_RS05215 1072008 1076261 + intimin-like protein SinH gene gene1041 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05215 HW43_RS05220 HW43_05125 HW43_RS05220 1076382 1077239 - transcriptional regulator gene gene1042 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05220 HW43_RS05225 HW43_05130 HW43_RS05225 1077488 1078357 + aldo/keto reductase gene gene1043 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05225 HW43_RS05230 HW43_05135 HW43_RS05230 1078522 1079112 - membrane protein gene gene1044 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05230 HW43_RS05235 HW43_05140 HW43_RS05235 1079124 1079360 - hypothetical protein gene gene1045 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05235 HW43_RS05240 HW43_05145 HW43_RS05240 1079469 1080794 - pyridine nucleotide-disulfide oxidoreductase Involved in disulfide oxidoreductase activity and electron transport gene gene1046 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05240 HW43_RS05245 HW43_05150 HW43_RS05245 1081020 1081874 + AraC family transcriptional regulator gene gene1047 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05245 HW43_RS05250 HW43_05155 HW43_RS05250 1082401 1083120 + oxidoreductase gene gene1048 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05250 HW43_RS05255 HW43_05160 HW43_RS05255 1083131 1084558 + amino acid dehydrogenase gene gene1049 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05255 HW43_RS05260 HW43_05165 HW43_RS05260 1084551 1085246 + hypothetical protein gene gene1050 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05260 HW43_RS05265 HW43_24670 HW43_RS05265 1085320 1085442 - universal stress protein gene gene1051 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05265 HW43_RS05270 HW43_05170 HW43_RS05270 1085489 1086157 - membrane protein gene gene1052 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05270 HW43_RS05275 HW43_05175 HW43_RS05275 1086341 1088638 - autotransporter gene gene1053 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05275 HW43_RS05280 HW43_05180 HW43_RS05280 1088680 1089231 - hypothetical protein gene gene1054 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05280 HW43_RS05285 HW43_05185 HW43_RS05285 1089595 1090389 - LuxR family transcriptional regulator gene gene1055 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05285 HW43_RS05290 HW43_24675 HW43_RS05290 1090719 1091281 - DNA recombinase gene gene1056 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05290 HW43_RS05295 HW43_24680 HW43_RS05295 1092086 1092337 + hypothetical protein gene gene1057 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05295 HW43_RS05300 HW43_05195 HW43_RS05300 1092356 1094026 - oxygen-dependent choline dehydrogenase catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine gene gene1058 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05300 HW43_RS05305 HW43_05200 HW43_RS05305 1094040 1095512 - NAD/NADP-dependent betaine aldehyde dehydrogenase gene gene1059 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05305 HW43_RS05310 HW43_05205 HW43_RS05310 1095526 1096113 - transcriptional regulator HTH-type%3B bet1%3B Repressor involved in choline regulation of the bet genes gene gene1060 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05310 HW43_RS05315 HW43_05210 HW43_RS05315 1096242 1098275 + choline transporter proton-motive-force-driven choline transporter gene gene1061 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05315 HW43_RS05320 HW43_24685 HW43_RS05320 1098645 1098830 - hypothetical protein gene gene1062 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05320 HW43_RS05325 HW43_05215 HW43_RS05325 1099150 1100238 + cyclic di-GMP phosphodiesterase gene gene1063 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05325 HW43_RS05330 HW43_05220 HW43_RS05330 1100280 1101212 - LysR family transcriptional regulator gene gene1064 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05330 HW43_RS05335 HW43_05225 HW43_RS05335 1101304 1101801 - membrane protein gene gene1065 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05335 HW43_RS05340 HW43_05230 HW43_RS05340 1102059 1102664 + transcriptional regulator gene gene1066 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05340 HW43_RS05345 HW43_05235 HW43_RS05345 1102704 1103567 + hypothetical protein gene gene1067 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05345 HW43_RS05350 HW43_05240 HW43_RS05350 1103557 1105104 + hypothetical protein gene gene1068 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05350 HW43_RS05355 HW43_05245 HW43_RS05355 1105104 1106522 + hypothetical protein gene gene1069 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05355 HW43_RS05360 HW43_05250 HW43_RS05360 1106666 1107616 + carbamate kinase gene gene1070 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05360 HW43_RS05365 HW43_05255 HW43_RS05365 1107626 1109008 + deaminase metallo-dependent hydrolase superfamily%3B deaminase with metallo-dependent hydrolase domain gene gene1071 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05365 HW43_RS05370 HW43_05260 HW43_RS05370 1109307 1109717 + hypothetical protein gene gene1072 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05370 HW43_RS05375 HW43_05265 HW43_RS05375 1109971 1110954 + LacI family transcriptional regulator gene gene1073 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05375 HW43_RS05380 HW43_05270 HW43_RS05380 1111003 1112487 + sugar ABC transporter ATP-binding protein gene gene1074 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05380 HW43_RS05385 HW43_05275 HW43_RS05385 1112480 1113451 + ABC transporter permease gene gene1075 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05385 HW43_RS05390 HW43_05280 HW43_RS05390 1113448 1114404 + sugar ABC transporter permease gene gene1076 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05390 HW43_RS05395 HW43_05285 HW43_RS05395 1114491 1115540 + aldehyde reductase YahK gene gene1077 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05395 HW43_RS05400 HW43_05290 HW43_RS05400 1115783 1116598 + hypothetical protein gene gene1078 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05400 HW43_RS05405 HW43_05295 HW43_RS05405 1117011 1117256 + hypothetical protein gene gene1079 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05405 HW43_RS05410 HW43_05300 HW43_RS05410 1117273 1117905 - membrane protein gene gene1080 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05410 HW43_RS05415 HW43_05305 HW43_RS05415 1118091 1118366 + periplasmic protein%2C function unknown%2C YhcN family gene gene1081 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05415 HW43_RS05420 HW43_05310 HW43_RS05420 1118467 1120053 - propionate catabolism operon regulatory protein PrpR sigma-54 dependent activator family protein%3B activates the prpBCDE operon gene gene1082 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05420 HW43_RS05425 HW43_05315 prpB prpB 1120292 1121182 + methylisocitrate lyase catalyzes the formation of pyruvate and succinate from 2-methylisocitrate gene gene1083 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05425 HW43_RS05430 HW43_05320 HW43_RS05430 1121227 1122396 + methylcitrate synthase catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate%3B also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity gene gene1084 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05430 HW43_RS05435 HW43_05325 prpD prpD 1122430 1123881 + 2-methylcitrate dehydratase functions in propionate metabolism%3B involved in isomerization of (2S%2C3S)-methylcitrate to (2R%2C3S)-methylisocitrate%3B also encodes minor aconitase or dehydratase activity%3B aconitase C gene gene1085 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05435 HW43_RS05440 HW43_05330 prpE prpE 1123921 1125807 + propionate--CoA ligase catalyzes the formation of propionyl-CoA using propionate as a substrate%3B PrpE from Ralstonia solanacearum can produce acetyl-%2C propionyl-%2C butyryl- and acrylyl-coenzyme A%2C and Salmonella enterica produces propionyl- and butyryl-coenzyme A%3B not expressed in Escherichia coli when grown on propionate/minimal media%3B ATP-dependent gene gene1086 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05440 HW43_RS05445 HW43_05335 codB codB 1126145 1127404 + cytosine permease gene gene1087 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05445 HW43_RS05450 HW43_05340 HW43_RS05450 1127394 1128677 + cytosine deaminase Catalyzes the deamination of cytosine to uracil and ammonia gene gene1088 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05450 HW43_RS05455 HW43_05345 HW43_RS05455 1128717 1129616 - MerR family transcriptional regulator controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source gene gene1089 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05455 HW43_RS05460 HW43_05350 HW43_RS05460 1129726 1130385 + carbonic anhydrase gene gene1090 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05460 HW43_RS05465 HW43_05355 HW43_RS05465 1130416 1130886 + cyanate hydratase gene gene1091 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05465 HW43_RS05470 HW43_05360 cynX cynX 1130892 1132073 + cyanate transporter MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon%3B not essential gene gene1092 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05470 HW43_RS05475 HW43_05365 lacY lacY 1132152 1133405 - lactose permease lactose/proton symporter%3B mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides%3B member of major facilitator superfamily%3B functions as a monomer with 12 transmembrane segments gene gene1093 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05475 HW43_RS05480 HW43_05370 lacZ lacZ 1133457 1136531 - beta-D-galactosidase forms a homotetramer%3B hydrolyzes lactose disaccharide to galactose and glucose%3B converts lactose to allolactose which is the natural inducer of the lac operon gene gene1094 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05480 HW43_RS05485 HW43_05375 lacI lacI 1136654 1137613 - lac repressor transcriptional repressor of lac operon%3B forms a homotetramer as a dimer of dimers%3B binds specific sites in lac operon resulting in DNA looping between the operators%3B binds allolactose as inducer gene gene1095 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05485 HW43_RS05490 HW43_05380 HW43_RS05490 1137813 1138646 - transcriptional regulator activator of 3-phenylpropionic acid catabolism gene gene1096 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05490 HW43_RS05495 HW43_05385 mhpA mhpA 1138837 1140501 + 3-(3-hydroxyphenyl)propionate hydroxylase catalyzes the formation of 3-(2%2C3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate gene gene1097 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05495 HW43_RS05500 HW43_05390 mhpB mhpB 1140503 1141447 + 2%2C3-dihydroxyphenylpropionate/2%2C3-dihydroxicinnamic acid 1%2C2-dioxygenase catalyzes the cleavage of 3-(2%2C3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2%2C4-diene-1%2C9-dioate%3B part of the 3-phenylpropionic acid degradation pathway%3B member of the protocatechuate 4%2C5-dioxygenase family gene gene1098 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05500 HW43_RS05505 HW43_05395 HW43_RS05505 1141465 1142331 + 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase gene gene1099 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05505 HW43_RS05510 HW43_05400 HW43_RS05510 1142341 1143150 + 2-keto-4-pentenoate hydratase gene gene1100 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05510 HW43_RS05515 HW43_05405 HW43_RS05515 1143147 1144097 + acetaldehyde dehydrogenase catalyzes the formation of acetyl-CoA from acetalaldehyde gene gene1101 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05515 HW43_RS05520 HW43_05410 HW43_RS05520 1144094 1145107 + 4-hydroxy-2-oxovalerate aldolase catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid%3B involved in the degradation of phenylpropionate gene gene1102 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05520 HW43_RS05525 HW43_05415 HW43_RS05525 1145283 1146494 + 3-(3-hydroxy-phenyl)propionate transporter gene gene1103 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05525 HW43_RS05530 HW43_05420 HW43_RS05530 1146596 1147135 + DUF2058 domain-containing protein gene gene1104 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05530 HW43_RS05535 HW43_05425 HW43_RS05535 1147260 1148093 - S-formylglutathione hydrolase gene gene1105 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05535 HW43_RS05540 HW43_05430 HW43_RS05540 1148186 1149295 - S-(hydroxymethyl)glutathione dehydrogenase catalyzes the formation of S-formylglutathione from S-(hydroxymethyl)glutathione%3B also catalyzes the formation of aldehyde or ketone from alcohols gene gene1106 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05540 HW43_RS05545 HW43_05435 HW43_RS05545 1149330 1149605 - transcriptional regulator formaldehyde-induced negative regulator of the frmRAB operon gene gene1107 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05545 HW43_RS05550 HW43_05440 HW43_RS05550 1149791 1150564 - membrane protein gene gene1108 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05550 HW43_RS05555 HW43_05445 HW43_RS05555 1150566 1151006 - transferase gene gene1109 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05555 HW43_RS05560 HW43_05450 HW43_RS05560 1151125 1152321 - membrane protein gene gene1110 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05560 HW43_RS05565 HW43_05455 HW43_RS05565 1152331 1153002 - hypothetical protein gene gene1111 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05565 HW43_RS05570 HW43_05460 tauA tauA 1153618 1154580 + taurine ABC transporter substrate-binding protein with TauB and TauC is responsible for taurine uptake. gene gene1112 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05570 HW43_RS05575 HW43_05465 tauB tauB 1154593 1155360 + taurine ABC transporter ATP-binding protein Part of the ABC transporter complex tauABC involved in taurine import gene gene1113 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05575 HW43_RS05580 HW43_05470 HW43_RS05580 1155357 1156184 + taurine ABC transporter permease gene gene1114 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05580 HW43_RS05585 HW43_05475 tauD tauD 1156181 1157032 + taurine dioxygenase catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide%3B non-heme iron oxidase%3B allows the use of taurine as an alternative sulfur source%3B forms homodimers gene gene1115 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05585 HW43_RS05590 HW43_05480 HW43_RS05590 1157138 1158112 - delta-aminolevulinic acid dehydratase gene gene1116 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05590 HW43_RS05595 HW43_05485 HW43_RS05595 1158635 1161586 + membrane protein gene gene1117 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05595 HW43_RS05600 HW43_05490 HW43_RS05600 1161674 1162297 + transcriptional regulator gene gene1118 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05600 HW43_RS05605 HW43_05495 HW43_RS05605 1162298 1163455 - beta-lactam-binding protein AmpH this protein has no known enzymatic function gene gene1119 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05605 HW43_RS05610 HW43_24690 HW43_RS05610 1163593 1163787 + hypothetical protein gene gene1120 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05610 HW43_RS05615 HW43_05500 HW43_RS05615 1163807 1165027 + microcin B17 transporter in Escherichia coli SbmA is involved in uptake of microcin J25%3B functions along with FhuA%2C TonB%2C and ExbB/D in this capacity%3B in Sinorhizobium meliloti%2C BacA is essential and required for symbiosis%3B defects appear to affect the cell envelope gene gene1121 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05615 HW43_RS05620 HW43_05505 HW43_RS05620 1165040 1166134 + hypothetical protein gene gene1122 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05620 HW43_RS05625 HW43_05510 HW43_RS05625 1166193 1166501 - hypothetical protein gene gene1123 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05625 HW43_RS05630 HW43_05515 HW43_RS05630 1166761 1166973 + DUF2754 domain-containing protein gene gene1124 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05630 HW43_RS05635 HW43_05520 HW43_RS05635 1166997 1168091 - D-alanine--D-alanine ligase A gene gene1125 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05635 HW43_RS05640 HW43_24695 HW43_RS05640 1168172 1168372 + hypothetical protein gene gene1126 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05640 HW43_RS05645 HW43_05525 HW43_RS05645 1168554 1168814 + anti-adapter protein IraP RpoS stabilzer during Pi starvation%3B anti-adapter protein gene gene1127 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05645 HW43_RS05650 HW43_05530 HW43_RS05650 1168915 1170330 + alkaline phosphatase gene gene1128 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05650 HW43_RS05655 HW43_05535 HW43_RS05655 1170449 1170769 + phosphate starvation-inducible protein PsiF gene gene1129 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05655 HW43_RS05660 HW43_05540 adrA adrA 1170871 1171986 + diguanylate cyclase catalyzes the conversion of 2 GTP into c-di-GMP%3B adrA overexpression induces cellulose biosynthesis%2C cell adherence to abiotic surfaces and swimming and swarming motility%3B AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis gene gene1130 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05660 HW43_RS05665 HW43_05545 HW43_RS05665 1172003 1172812 - pyrroline-5-carboxylate reductase catalyzes the formation of L-proline from pyrroline-5-carboxylate gene gene1131 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05665 HW43_RS05670 HW43_05550 HW43_RS05670 1172932 1173390 + hypothetical protein gene gene1132 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05670 HW43_RS05675 HW43_05555 aroL aroL 1173573 1174097 + shikimate kinase type II enzyme similar to type I but differentially regulated and with a lower Km%3B catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis gene gene1133 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05675 HW43_RS05680 HW43_05560 HW43_RS05680 1174147 1174338 + hypothetical protein gene gene1134 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05680 HW43_RS05685 HW43_24700 HW43_RS05685 1174369 1174566 + hypothetical protein gene gene1135 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05685 HW43_RS05690 HW43_05565 HW43_RS05690 1174596 1175273 + protein AroM gene gene1136 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05690 HW43_RS05695 HW43_05570 HW43_RS05695 1175345 1175629 + hypothetical protein gene gene1137 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05695 HW43_RS05700 HW43_05575 HW43_RS05700 1175833 1176252 + hypothetical protein gene gene1138 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05700 HW43_RS05705 HW43_05580 HW43_RS05705 1176330 1177241 - recombination-associated protein RdgC Required for efficient pilin antigenic variation gene gene1139 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05705 HW43_RS05710 HW43_05585 HW43_RS05710 1177366 1178274 + fructokinase catalyzes phosphorylation of fructose%3B cytosolic enzyme gene gene1140 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05710 HW43_RS05715 HW43_05590 HW43_RS05715 1178417 1179601 - MFS transporter member of the major facilitator superfamily (MFS) of transporters%3B unknown function%3B may be associated with transport or processing of arabinose polymers gene gene1141 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05715 HW43_RS05720 HW43_05595 HW43_RS05720 1179727 1182870 - exonuclease subunit SbcC with SbcD cleaves DNA hairpin structures%3B also has 5' single-strand endonuclease activity gene gene1142 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05720 HW43_RS05725 HW43_05600 HW43_RS05725 1182867 1184069 - nuclease SbcCD subunit D with SbcC cleaves DNA hairpin structure%2C also has 5' single-strand endonuclease activity gene gene1143 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05725 HW43_RS05730 HW43_05605 HW43_RS05730 1184259 1184948 + two-component system response regulator two component response regulator for the phosphate regulon%3B PhoR phosphorylates PhoB gene gene1144 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05730 HW43_RS05735 HW43_05610 phoR phoR 1185006 1186301 + phosphate regulon sensor protein membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB gene gene1145 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05735 HW43_RS05740 HW43_05615 HW43_RS05740 1186708 1188027 + branched-chain amino acid transport system 2 carrier protein sodium:branched-chain amino acid symporter gene gene1146 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05740 HW43_RS05745 HW43_05620 proY proY 1188103 1189476 + proline-specific permease ProY cryptic permease that may be involved in the transport of proline across the inner membrane%3B in Salmonella typhimurium%2C the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation gene gene1147 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05745 HW43_RS05750 HW43_05625 HW43_RS05750 1189632 1191449 + maltodextrin glucosidase gene gene1148 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05750 HW43_RS05755 HW43_05630 HW43_RS05755 1191454 1192035 - ACP phosphodiesterase Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP gene gene1149 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05755 HW43_RS05760 HW43_05635 queA queA 1192128 1193198 + S-adenosylmethionine:tRNA ribosyltransferase-isomerase Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step gene gene1150 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05760 HW43_RS05765 HW43_05640 tgt tgt 1193254 1194381 + queuine tRNA-ribosyltransferase Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp%2C -Asn%2C -His and -Tyr) gene gene1151 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05765 HW43_RS05770 HW43_05645 yajC yajC 1194404 1194736 + preprotein translocase subunit YajC member of preprotein translocase%3B forms a heterotrimer with SecD and SecF%3B links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex gene gene1152 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05770 HW43_RS05775 HW43_05650 secD secD 1194764 1196611 + preprotein translocase subunit SecD part of the preprotein secretory system%3B when complexed with proteins SecF and YajC%2C SecDFyajC stimulates the proton motive force-driven protein translocation%2C and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane gene gene1153 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05775 HW43_RS05780 HW43_05655 HW43_RS05780 1196622 1197593 + protein translocase subunit SecF gene gene1154 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05780 HW43_RS05785 HW43_05660 HW43_RS05785 1197722 1198069 + hypothetical protein gene gene1155 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05785 HW43_RS05790 HW43_24705 HW43_RS05790 1198083 1198205 + hypothetical protein gene gene1156 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05790 HW43_RS05795 HW43_05665 HW43_RS05795 1198246 1199130 - nucleoside-specific channel-forming protein tsx receptor of phage T6 and colicin K%3B involved in the transfer of deoxyribo- and ribo-nucleotides across the outer membrane gene gene1157 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05795 HW43_RS05800 HW43_05670 HW43_RS05800 1199429 1199968 - hypothetical protein gene gene1158 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05800 HW43_RS05805 HW43_05675 HW43_RS05805 1200119 1200568 + NrdR family transcriptional regulator gene gene1159 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05805 HW43_RS05810 HW43_05680 ribD ribD 1200572 1201675 + diaminohydroxyphosphoribosylaminopyrimidine deaminase riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway%3B catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2%2C5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil gene gene1160 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05810 HW43_RS05815 HW43_05685 ribH ribH 1201764 1202234 + 6%2C7-dimethyl-8-ribityllumazine synthase RibE%3B 6%2C7-diimethyl-8-ribityllumazine synthase%3B DMRL synthase%3B lumazine synthase%3B beta subunit of riboflavin synthase%3B condenses 5-amino-6-(1'-D)-ribityl-amino-2%2C4(1H%2C3H)-pyrimidinedione with L-3%2C4-dihydrohy-2-butanone-4-phosphate to generate 6%2C6-dimethyl-8-lumazine (DMRL)%3B riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12)%3B involved in the last steps of riboflavin biosynthesis%3B forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli%3B in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not gene gene1161 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05815 HW43_RS05820 HW43_05690 nusB nusB 1202254 1202673 + transcription antitermination protein NusB Regulates rRNA biosynthesis by transcriptional antitermination gene gene1162 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05820 HW43_RS05825 HW43_05695 HW43_RS05825 1202751 1203728 + thiamine monophosphate kinase catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP gene gene1163 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05825 HW43_RS05830 HW43_05700 HW43_RS05830 1203706 1204224 + phosphatidylglycerophosphatase A hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate gene gene1164 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05830 HW43_RS05835 HW43_05705 HW43_RS05835 1204278 1205252 - oxidoreductase gene gene1165 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05835 HW43_RS05840 HW43_05710 HW43_RS05840 1205307 1207169 - 1-deoxy-D-xylulose-5-phosphate synthase catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate gene gene1166 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05840 HW43_RS05845 HW43_05715 HW43_RS05845 1207194 1208093 - farnesyl-diphosphate synthase gene gene1167 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05845 HW43_RS05850 HW43_05720 HW43_RS05850 1208093 1208335 - exodeoxyribonuclease 7 small subunit catalyzes the bidirectional exonucleolytic cleavage of DNA gene gene1168 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05850 HW43_RS05855 HW43_05725 HW43_RS05855 1208541 1209989 + tRNA sulfurtransferase catalyzes the conversion of uridine to 4-thiouridinine tRNA%3B also required for the synthesis of the thiazole moiety gene gene1169 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05855 HW43_RS05860 HW43_05730 HW43_RS05860 1210043 1210633 - oxidative-stress-resistance chaperone gene gene1170 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05860 HW43_RS05865 HW43_05735 HW43_RS05865 1210596 1211507 - 2-dehydropantoate 2-reductase ketopantoate reductase%3B catalyzes the NADPH reduction of ketopantoate to pantoate%3B functions in pantothenate (vitamin B5) biosynthesis gene gene1171 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05865 HW43_RS05870 HW43_05740 HW43_RS05870 1211675 1212166 + nucleotide-binding protein nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ%3B the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription gene gene1172 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05870 HW43_RS05875 HW43_05745 HW43_RS05875 1212294 1213658 - membrane protein gene gene1173 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05875 HW43_RS05880 HW43_05750 HW43_RS05880 1214066 1215001 + hypothetical protein gene gene1174 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05880 HW43_RS05885 HW43_05755 HW43_RS05885 1215057 1215599 - acetyltransferase gene gene1175 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05885 HW43_RS05890 HW43_05760 HW43_RS05890 1215583 1215894 - hypothetical protein gene gene1176 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05890 HW43_RS05895 HW43_05765 HW43_RS05895 1216079 1216969 - protoheme IX farnesyltransferase converts protoheme IX and farnesyl diphosphate to heme O gene gene1177 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05895 HW43_RS05900 HW43_05770 HW43_RS05900 1216981 1217310 - cytochrome bo(3) ubiquinol oxidase subunit 4 gene gene1178 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05900 HW43_RS05905 HW43_05775 HW43_RS05905 1217310 1217924 - cytochrome bo(3) ubiquinol oxidase subunit 3 gene gene1179 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05905 HW43_RS05910 HW43_05780 HW43_RS05910 1217914 1219905 - cytochrome bo(3) ubiquinol oxidase subunit 1 gene gene1180 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05910 HW43_RS05915 HW43_05785 HW43_RS05915 1219927 1220874 - cytochrome O ubiquinol oxidase gene gene1181 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05915 HW43_RS05920 HW43_05790 ampG ampG 1221336 1222811 - AmpG family muropeptide MFS transporter in Escherichia coli this protein is a permease involved in peptidoglycan recycling%3B member of major facilitator superfamily%3B MFS%3B inner membrane protein gene gene1182 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05920 HW43_RS05925 HW43_05795 HW43_RS05925 1222855 1223433 - hypothetical protein gene gene1183 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05925 HW43_RS05930 HW43_05800 HW43_RS05930 1223738 1224055 + protein BolA positive transcriptional regulator of morphogenetic pathway%3B controlling several genes involved in oxidative stress%2C acid stress%2C heat shock%2C osmotic shock%2C and carbon-starvation stress gene gene1184 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05930 HW43_RS05935 HW43_05805 HW43_RS05935 1224064 1224252 + hypothetical protein gene gene1185 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05935 HW43_RS05940 HW43_05810 HW43_RS05940 1224399 1225697 + trigger factor gene gene1186 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05940 HW43_RS05945 HW43_05815 HW43_RS05945 1225943 1226566 + ATP-dependent Clp protease proteolytic subunit gene gene1187 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05945 HW43_RS05950 HW43_05820 clpX clpX 1226692 1227966 + ATP-dependent Clp protease ATP-binding subunit ClpX binds and unfolds substrates as part of the ClpXP protease gene gene1188 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05950 HW43_RS05955 HW43_05825 HW43_RS05955 1228154 1230508 + lon protease gene gene1189 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05955 HW43_RS05960 HW43_05830 HW43_RS05960 1230717 1230989 + DNA-binding protein HU-beta histone-like DNA-binding protein gene gene1190 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05960 HW43_RS05965 HW43_05835 HW43_RS05965 1231181 1233052 + peptidyl-prolyl cis-trans isomerase gene gene1191 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05965 HW43_RS05970 HW43_05840 HW43_RS05970 1233203 1233574 + hypothetical protein gene gene1192 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05970 HW43_RS05975 HW43_05845 HW43_RS05975 1233668 1234066 + long-chain acyl-CoA thioesterase FadM gene gene1193 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05975 HW43_RS05980 HW43_05850 HW43_RS05980 1234118 1234813 - 7-cyano-7-deazaguanine synthase YbaX%3B catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0)%2C as one of the early reactions of quenosine biosynthesis%3B quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn%2C Asp%2C Tyr%2C and His gene gene1194 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05980 HW43_RS05985 HW43_05855 HW43_RS05985 1234878 1236491 - hypothetical protein gene gene1195 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05985 HW43_RS05990 HW43_05860 HW43_RS05990 1236591 1237409 + HMP-PP phosphatase HMP-PP phosphatase%3B catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) gene gene1196 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05990 HW43_RS05995 HW43_05865 HW43_RS05995 1237562 1238020 + transcriptional regulator gene gene1197 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS05995 HW43_RS06000 HW43_05870 HW43_RS06000 1238050 1239822 + multidrug ABC transporter ATP-binding protein gene gene1198 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06000 HW43_RS06005 HW43_05875 HW43_RS06005 1239815 1241596 + multidrug ABC transporter ATP-binding protein gene gene1199 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06005 HW43_RS06010 HW43_05880 HW43_RS06010 1241777 1242115 + nitrogen regulatory protein P-II 2 indirectly regulates nitrogen metabolism%3B at high nitrogen levels P-II prevents the phosphorylation of NR-I%2C the transcriptional activator of the glutamine synthetase gene (glnA)%3B at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA gene gene1200 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06010 HW43_RS06015 HW43_05885 HW43_RS06015 1242145 1243431 + ammonia channel gene gene1201 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06015 HW43_RS06020 HW43_05890 HW43_RS06020 1243479 1244339 - acyl-CoA thioesterase 2 gene gene1202 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06020 HW43_RS06025 HW43_05895 HW43_RS06025 1244557 1245129 + hypothetical protein gene gene1203 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06025 HW43_RS06030 HW43_05900 HW43_RS06030 1245160 1245471 - methylated-DNA--protein-cysteine methyltransferase gene gene1204 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06030 HW43_RS06035 HW43_05905 HW43_RS06035 1245850 1246203 + DUF1428 domain-containing protein gene gene1205 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06035 HW43_RS06040 HW43_05910 HW43_RS06040 1246245 1247795 - hypothetical protein gene gene1206 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06040 HW43_RS06045 HW43_05915 HW43_RS06045 1247959 1248429 - hypothetical protein gene gene1207 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06045 HW43_RS06050 HW43_05920 HW43_RS06050 1248545 1249096 - maltose O-acetyltransferase gene gene1208 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06050 HW43_RS06055 HW43_05925 HW43_RS06055 1249268 1249486 - hemolysin expression-modulating protein Hha with Hns involved in transcriptional regulation of hemolysin%3B non-specific DNA-binding protein which affects the production of multiple proteins gene gene1209 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06055 HW43_RS06060 HW43_05930 HW43_RS06060 1249512 1249886 - Hha toxicity modulator TomB gene gene1210 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06060 HW43_RS06065 HW43_05935 HW43_RS06065 1250432 1253581 - multidrug efflux RND transporter permease subunit gene gene1211 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06065 HW43_RS06070 HW43_05940 HW43_RS06070 1253604 1254797 - MexE family multidrug efflux RND transporter periplasmic adaptor subunit with AcrD and TolC forms a transport system involved in resistance to a number of compounds including lipophilic antibiotics gene gene1212 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06070 HW43_RS06075 HW43_05945 HW43_RS06075 1254939 1255586 + transcriptional regulator regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine gene gene1213 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06075 HW43_RS06080 HW43_05950 HW43_RS06080 1255714 1259076 + hypothetical protein gene gene1214 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06080 HW43_RS06085 HW43_24710 HW43_RS06085 1259111 1259254 - hypothetical protein gene gene1215 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06085 HW43_RS06090 HW43_24715 HW43_RS06090 1259288 1259449 - hypothetical protein gene gene1216 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06090 HW43_RS06095 HW43_05960 HW43_RS06095 1259463 1259990 - primosomal replication protein N'' PriC%3B protein involved in DNA replication%3B part of the primosome%2C a protein complex required to restart stalled replication forks%3B binds the complex formed by PriA%2C PriB and DNA%3B PriC-dependent primosome requires a gap to restart DNA replication%3B stimulates Rep activity at stalled forks gene gene1217 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06095 HW43_RS06100 HW43_05965 HW43_RS06100 1260060 1260437 + hypothetical protein gene gene1218 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06100 HW43_RS06105 HW43_05970 HW43_RS06105 1260590 1261141 + adenine phosphoribosyltransferase catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis gene gene1219 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06105 HW43_RS06110 HW43_05975 HW43_RS06110 1261270 1263201 + DNA polymerase III subunit gamma/tau catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand%3B the tau chain serves as a scaffold to help in the dimerizaton of the alpha%2Cepsilon and theta core complex%3B the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA gene gene1220 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06110 HW43_RS06115 HW43_05980 HW43_RS06115 1263254 1263583 + nucleoid-associated protein gene gene1221 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06115 HW43_RS06120 HW43_05985 recR recR 1263583 1264188 + recombination protein RecR involved in a recombinational process of DNA repair%2C independent of the recBC complex gene gene1222 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06120 HW43_RS06125 HW43_05990 HW43_RS06125 1264298 1266172 + chaperone protein HtpG molecular chaperone gene gene1223 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06125 HW43_RS06130 HW43_05995 adk adk 1266353 1266997 + adenylate kinase essential enzyme that recycles AMP in active cells%3B converts ATP and AMP to two molecules of ADP gene gene1224 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06130 HW43_RS06135 HW43_06000 HW43_RS06135 1267233 1268195 + ferrochelatase gene gene1225 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06135 HW43_RS06140 HW43_06005 HW43_RS06140 1268192 1269151 - acetyl esterase gene gene1226 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06140 HW43_RS06145 HW43_06010 HW43_RS06145 1269303 1270607 + inosine-guanosine kinase catalyzes the formation of inosine/guanosine monophosphate from inosine or guanosine and ATP gene gene1227 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06145 HW43_RS06150 HW43_06015 HW43_RS06150 1270690 1272366 - cation:proton antiport protein YbaL%3B member of the CPA-2 family of antiporters%3B uncharacterized protein gene gene1228 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06150 HW43_RS06155 HW43_06020 HW43_RS06155 1272604 1273824 - fosmidomycin resistance protein gene gene1229 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06155 HW43_RS06160 HW43_06025 ushA ushA 1274042 1275694 + protein UshA catalyzes the degradation of periplasmic UDP-glucose to uridine%2C glucose-1-phosphate and inorganic phosphate%3B specific for uridine nucleotides gene gene1230 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06160 HW43_RS06165 HW43_06030 HW43_RS06165 1275731 1276210 - cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK gene gene1231 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06165 HW43_RS06170 HW43_06035 HW43_RS06170 1276414 1277208 - hypothetical protein gene gene1232 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06170 HW43_RS06175 HW43_06040 HW43_RS06175 1277346 1277687 + XRE family transcriptional regulator gene gene1233 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06175 HW43_RS06180 HW43_06045 copA copA 1277801 1280305 - copper exporting ATPase gene gene1234 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06180 HW43_RS06185 HW43_06050 HW43_RS06185 1280567 1281499 + glutaminase catalyzes the formation of glutamate from glutamine gene gene1235 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06185 HW43_RS06190 HW43_06055 HW43_RS06190 1281502 1282794 + transporter gene gene1236 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06190 HW43_RS06195 HW43_06060 HW43_RS06195 1282919 1283326 + transcriptional regulator activator of copper-responsive regulon genes gene gene1237 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06195 HW43_RS06200 HW43_06065 HW43_RS06200 1283327 1283785 - hypothetical protein gene gene1238 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06200 HW43_RS06205 HW43_06070 HW43_RS06205 1283782 1284699 - protein QmcA gene gene1239 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06205 HW43_RS06210 HW43_06075 HW43_RS06210 1284845 1285522 + iron export ATP-binding protein FetA gene gene1240 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06210 HW43_RS06215 HW43_06080 HW43_RS06215 1285509 1286288 + membrane protein gene gene1241 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06215 HW43_RS06220 HW43_06085 HW43_RS06220 1286351 1287205 - hypothetical protein gene gene1242 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06220 HW43_RS06225 HW43_06090 HW43_RS06225 1287266 1288036 - oxidoreductase gene gene1243 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06225 HW43_RS06230 HW43_06095 HW43_RS06230 1288065 1288688 - multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 gene gene1244 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06230 HW43_RS06235 HW43_06100 HW43_RS06235 1288659 1289345 + ABC transporter ATP-binding protein gene gene1245 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06235 HW43_RS06240 HW43_06105 HW43_RS06240 1289342 1291756 + sugar ABC transporter permease gene gene1246 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06240 HW43_RS06245 HW43_06110 HW43_RS06245 1292185 1296294 + RHS element protein RhsA gene gene1247 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06245 HW43_RS06250 HW43_06115 HW43_RS06250 1296275 1296766 + hypothetical protein gene gene1248 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06250 HW43_RS06255 HW43_06120 HW43_RS06255 1297281 1297652 - hypothetical protein gene gene1249 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06255 HW43_RS06260 HW43_06125 HW43_RS06260 1297768 1298862 - tRNA 2-selenouridine synthase catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA gene gene1250 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06260 HW43_RS06265 HW43_06130 HW43_RS06265 1298931 1299857 - HTH-type transcriptional activator AllS activator of the allDC-ylbA operon involved in allantoin utilization gene gene1251 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06265 HW43_RS06270 HW43_06135 HW43_RS06270 1300087 1300569 + ureidoglycolate lyase gene gene1252 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06270 HW43_RS06275 HW43_06140 HW43_RS06275 1300647 1301462 + transcriptional regulator regulates operons involved in the utilization of allantoin gene gene1253 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06275 HW43_RS06280 HW43_06145 HW43_RS06280 1301552 1303333 + glyoxylate carboligase catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate gene gene1254 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06280 HW43_RS06285 HW43_06150 HW43_RS06285 1303346 1304122 + hydroxypyruvate isomerase gene gene1255 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06285 HW43_RS06290 HW43_06155 HW43_RS06290 1304222 1305100 + 2-hydroxy-3-oxopropionate reductase NADH-dependent%3B catalyzed the reversible formation of glycerate from tartronate semialdehyde gene gene1256 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06290 HW43_RS06295 HW43_06160 HW43_RS06295 1305269 1306723 + allantoin permease gene gene1257 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06295 HW43_RS06300 HW43_33830 HW43_RS06300 1306926 1307945 + transposase gene gene1258 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06300 HW43_RS06305 HW43_24720 HW43_RS06305 1308225 1309586 + allantoinase Plays a crucial role on both purine and pyrimidine metabolism gene gene1259 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06305 HW43_RS06310 HW43_06175 HW43_RS06310 1309643 1310944 + purine permease gene gene1260 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06310 HW43_RS06315 HW43_06180 HW43_RS06315 1310966 1312111 + glycerate kinase gene gene1261 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06315 HW43_RS06320 HW43_06185 HW43_RS06320 1312339 1313124 - (S)-ureidoglycine aminohydrolase gene gene1262 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06320 HW43_RS06325 HW43_06190 HW43_RS06325 1313135 1314370 - allantoate amidohydrolase gene gene1263 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06325 HW43_RS06330 HW43_06195 HW43_RS06330 1314392 1315441 - ureidoglycolate dehydrogenase catalyzes the formation of oxalurate from ureidoglycolate gene gene1264 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06330 HW43_RS06335 HW43_06200 HW43_RS06335 1315758 1317425 + membrane protein multicopy suppressor of dominant negative ftsH mutations%3B putative acyl-CoA synthetase gene gene1265 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06335 HW43_RS06340 HW43_06205 HW43_RS06340 1317435 1318694 + hypothetical protein gene gene1266 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06340 HW43_RS06345 HW43_06210 HW43_RS06345 1318705 1319499 + hypothetical protein gene gene1267 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06345 HW43_RS06350 HW43_06215 HW43_RS06350 1319517 1320410 + carbamate kinase reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP gene gene1268 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06350 HW43_RS06355 HW43_06220 HW43_RS06355 1320547 1321614 - phosphoribosylaminoimidazole carboxylase gene gene1269 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06355 HW43_RS06360 HW43_06225 purE purE 1321611 1322120 - N5-carboxyaminoimidazole ribonucleotide mutase catalyzes the formation of 4-carboxy-5-aminoimidazole ribonucleotide from N5-carboxyaminoimidazole ribonucleotide gene gene1270 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06360 HW43_RS06365 HW43_06230 HW43_RS06365 1322238 1322960 - UDP-2%2C3-diacylglucosamine hydrolase catalyzes the formation of 2%2C3%3Ddiacylglucosamine 1-phosphate from UDP-2%2C3%3Ddiacylglucosamine gene gene1271 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06365 HW43_RS06370 HW43_06235 HW43_RS06370 1322963 1323457 - peptidyl-prolyl cis-trans isomerase gene gene1272 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06370 HW43_RS06375 HW43_06240 cysS cysS 1323631 1325016 + cysteine--tRNA ligase catalyzes a two-step reaction%3B charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA gene gene1273 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06375 HW43_RS06380 HW43_06245 HW43_RS06380 1325052 1325573 - membrane protein gene gene1274 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06380 HW43_RS06385 HW43_06250 HW43_RS06385 1325681 1325893 - ribosome-associated protein gene gene1275 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06385 HW43_RS06390 HW43_06255 HW43_RS06390 1325895 1326761 - bifunctional protein FolD gene gene1276 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06390 HW43_RS06395 HW43_06260 HW43_RS06395 1327241 1327783 + FimA homolog%2C function unknown gene gene1277 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06395 HW43_RS06400 HW43_06265 HW43_RS06400 1328003 1328695 + molecular chaperone gene gene1278 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06400 HW43_RS06405 HW43_06270 HW43_RS06405 1328726 1331335 + fimbrial protein gene gene1279 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06405 HW43_RS06410 HW43_06275 fimH fimH 1331348 1332355 + adhesin involved in the regulation of fimbriae length and mediates adhesion of type 1 fimbriae gene gene1280 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06410 HW43_RS06415 HW43_06280 HW43_RS06415 1332366 1332881 + fimbrial protein gene gene1281 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06415 HW43_RS06420 HW43_06285 HW43_RS06420 1332884 1333516 - transcriptional regulator activates the production of the major fimbrae protein FimA gene gene1282 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06420 HW43_RS06425 HW43_06290 HW43_RS06425 1333759 1333835 + tRNA-Arg tRNA gene1283 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06425 HW43_RS06430 HW43_06295 HW43_RS06430 1333851 1335014 - integrase gene gene1284 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06430 HW43_RS06435 HW43_06300 HW43_RS06435 1335241 1335546 - hypothetical protein gene gene1285 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06435 HW43_RS06440 HW43_06305 HW43_RS06440 1335546 1335908 - phage protein gene gene1286 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06440 HW43_RS06445 HW43_06310 HW43_RS06445 1335899 1336435 - hypothetical protein gene gene1287 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06445 HW43_RS06450 HW43_06315 HW43_RS06450 1336563 1337387 - hypothetical protein gene gene1288 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06450 HW43_RS06455 HW43_06320 HW43_RS06455 1337453 1337815 - phage protein gene gene1289 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06455 HW43_RS06460 HW43_24725 HW43_RS06460 1337915 1338112 + hypothetical protein gene gene1290 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06460 HW43_RS06465 HW43_06335 HW43_RS06465 1338285 1338800 + hypothetical protein gene gene1291 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06465 HW43_RS06470 HW43_06340 HW43_RS06470 1339015 1339689 - e14 prophage%3B repressor protein phage e14 gene gene1292 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06470 HW43_RS06475 HW43_06345 HW43_RS06475 1339780 1339980 + transcriptional regulator gene gene1293 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06475 HW43_RS06480 HW43_06350 HW43_RS06480 1340024 1340581 + hypothetical protein gene gene1294 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06480 HW43_RS06485 HW43_06355 HW43_RS06485 1340578 1340916 + hypothetical protein gene gene1295 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06485 HW43_RS06490 HW43_06360 HW43_RS06490 1340926 1341867 + hypothetical protein gene gene1296 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06490 HW43_RS06495 HW43_06365 HW43_RS06495 1341870 1342358 + hypothetical protein gene gene1297 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06495 HW43_RS06500 HW43_24730 HW43_RS06500 1342358 1343008 + methyltransferase gene gene1298 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06500 HW43_RS06505 HW43_06375 HW43_RS06505 1343093 1343476 + antitermination protein gene gene1299 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06505 HW43_RS06510 HW43_06380 HW43_RS06510 1343666 1344763 - porin gene gene1300 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06510 HW43_RS06515 HW43_06385 HW43_RS06515 1345352 1345567 + holin gene gene1301 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06515 HW43_RS06520 HW43_06390 HW43_RS06520 1345567 1346064 + lysozyme RrrD gene gene1302 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06520 HW43_RS06525 HW43_06395 HW43_RS06525 1346061 1346522 + endopeptidase gene gene1303 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06525 HW43_RS06530 HW43_06400 HW43_RS06530 1346554 1346847 - Lipoprotein bor homolog from lambdoid prophage DLP12 gene gene1304 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06530 HW43_RS06535 HW43_06405 HW43_RS06535 1347138 1347548 - hypothetical protein gene gene1305 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06535 HW43_RS06540 HW43_06410 HW43_RS06540 1347834 1348040 + DLP12 prophage%3B uncharacterized protein gene gene1306 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06540 HW43_RS06545 HW43_24735 HW43_RS06545 1348205 1348399 - hypothetical protein gene gene1307 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06545 HW43_RS06550 HW43_24740 HW43_RS06550 1348415 1348563 - hypothetical protein gene gene1308 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06550 HW43_RS06555 HW43_24745 HW43_RS06555 1348547 1348648 + DNA-packaging protein gene gene1309 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06555 HW43_RS06560 HW43_06415 HW43_RS06560 1348788 1349333 + protein convertase gene gene1310 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06560 HW43_RS06565 HW43_24750 HW43_RS06565 1349308 1350804 + terminase gene gene1311 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06565 HW43_RS06570 HW43_06425 HW43_RS06570 1350806 1351012 + Lambda prophage-derived head-to-tail joining protein W gene gene1312 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06570 HW43_RS06575 HW43_24755 HW43_RS06575 1351079 1351846 + chromosome partitioning protein ParB gene gene1313 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06575 HW43_RS06580 HW43_06435 HW43_RS06580 1351953 1352282 + tail protein gene gene1314 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06580 HW43_RS06585 HW43_06440 HW43_RS06585 1352282 1352980 + phage tail protein gene gene1315 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06585 HW43_RS06590 HW43_06445 HW43_RS06590 1352986 1353729 + phage tail protein gene gene1316 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06590 HW43_RS06595 HW43_06450 HW43_RS06595 1353726 1354298 + tail assembly protein gene gene1317 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06595 HW43_RS06600 HW43_06455 HW43_RS06600 1354359 1354715 + host specificity protein J gene gene1318 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06600 HW43_RS06605 HW43_06460 HW43_RS06605 1354793 1355347 + short-chain fatty acid transporter gene gene1319 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06605 HW43_RS06610 HW43_06465 HW43_RS06610 1355347 1355922 + tail assembly protein gene gene1320 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06610 HW43_RS06615 HW43_06470 HW43_RS06615 1356018 1356608 - DNA invertase gene gene1321 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06615 HW43_RS06620 HW43_06475 HW43_RS06620 1356925 1357158 - cold-shock protein gene gene1322 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06620 HW43_RS06625 HW43_06480 HW43_RS06625 1357706 1358362 - hypothetical protein gene gene1323 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06625 HW43_RS06630 HW43_06485 HW43_RS06630 1358431 1358736 + tail fiber assembly protein gene gene1324 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06630 HW43_RS06635 HW43_06490 HW43_RS06635 1358920 1360404 - hydrolase gene gene1325 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06635 HW43_RS06640 HW43_06495 HW43_RS06640 1360591 1361544 - outer membrane protease gene gene1326 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06640 HW43_RS06645 HW43_24760 HW43_RS06645 1361947 1362063 - hypothetical protein gene gene1327 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06645 HW43_RS06650 HW43_06500 HW43_RS06650 1362057 1362818 - AraC family transcriptional regulator involved in the thermoregulation of ompA%2C ompC%2C lamB and envelope proteins gene gene1328 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06650 HW43_RS06655 HW43_06505 HW43_RS06655 1363001 1363891 - hypothetical protein gene gene1329 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06655 HW43_RS06660 HW43_06510 HW43_RS06660 1363892 1366864 - membrane protein gene gene1330 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06660 HW43_RS06665 HW43_06515 nfrB nfrB 1366851 1369088 - bacteriophage N4 adsorption protein B gene gene1331 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06665 HW43_RS06670 HW43_06520 HW43_RS06670 1369357 1370493 - hypothetical protein gene gene1332 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06670 HW43_RS06675 HW43_06525 HW43_RS06675 1370970 1371167 - hypothetical protein gene gene1333 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06675 HW43_RS06680 HW43_24765 HW43_RS06680 1371458 1371619 - hypothetical protein gene gene1334 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06680 HW43_RS06685 HW43_06535 HW43_RS06685 1371745 1372005 - hypothetical protein gene gene1335 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06685 HW43_RS06690 HW43_RS06690 HW43_RS06690 1372038 1373027 - type IV secretion protein Rhs gene gene1336 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06690 HW43_RS06695 HW43_06545 HW43_RS06695 1374361 1374822 - hypothetical protein gene gene1337 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06695 HW43_RS06700 HW43_06550 HW43_RS06700 1374850 1376751 - type VI secretion system Vgr family protein gene gene1338 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06700 HW43_RS06705 HW43_06555 HW43_RS06705 1377488 1378936 - two-component system sensor histidine kinase gene gene1339 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06705 HW43_RS06710 HW43_06560 HW43_RS06710 1378926 1379609 - two-component system response regulator response regulator in two-component regulatory system with CusS%3B regulates the copper efflux system gene gene1340 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06710 HW43_RS06715 HW43_06565 HW43_RS06715 1379766 1381148 + cation transporter with CusA%2C CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver gene gene1341 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06715 HW43_RS06720 HW43_06570 HW43_RS06720 1381172 1381504 + cation transporter gene gene1342 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06720 HW43_RS06725 HW43_06575 HW43_RS06725 1381520 1382743 + metal RND transporter with CusA%2C CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver gene gene1343 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06725 HW43_RS06730 HW43_06580 HW43_RS06730 1382755 1385898 + cation efflux system protein CusA gene gene1344 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06730 HW43_RS06735 HW43_06585 HW43_RS06735 1386000 1387376 + aromatic amino acid transporter gene gene1345 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06735 HW43_RS06740 HW43_06590 HW43_RS06740 1387444 1388691 - miniconductance mechanosensitive channel gene gene1346 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06740 HW43_RS06745 HW43_06595 HW43_RS06745 1388799 1389452 - dihydropteridine reductase catalyzes the reduction of nitroaromatic compounds such as nitrofurazone%2C quinones and the anti-tumor agent CB1954%3B NAD(P)H-dependent%3B oxygen insensitive gene gene1347 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06745 HW43_RS06750 HW43_06600 HW43_RS06750 1389546 1389914 - DUF419 domain-containing protein gene gene1348 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06750 HW43_RS06755 HW43_06605 HW43_RS06755 1389979 1390227 - membrane protein gene gene1349 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06755 HW43_RS06760 HW43_06610 HW43_RS06760 1390293 1391411 - gamma-glutamyl:cysteine ligase gene gene1350 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06760 HW43_RS06765 HW43_24770 HW43_RS06765 1391426 1391587 + hypothetical protein gene gene1351 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06765 HW43_RS06770 HW43_24775 HW43_RS06770 1391618 1391818 - hypothetical protein gene gene1352 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06770 HW43_RS06775 HW43_06620 HW43_RS06775 1391853 1392005 + membrane protein gene gene1353 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06775 HW43_RS06780 HW43_06625 HW43_RS06780 1392356 1392508 + protein HokE gene gene1354 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06780 HW43_RS06785 HW43_06630 HW43_RS06785 1392630 1393259 - 4'-phosphopantetheinyl transferase gene gene1355 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06785 HW43_RS06790 HW43_06635 HW43_RS06790 1393425 1395665 - outer membrane receptor FepA Fep%3B Cbt%3B Cbr%3B FeuB%3B FepA%3B PfeA%3B IroN%3B BfeA%3B outer membrane receptor of ferric enterobactin and colicins B and D%3B interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space gene gene1356 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06790 HW43_RS06795 HW43_06640 HW43_RS06795 1395908 1397110 + enterobactin/ferric enterobactin esterase gene gene1357 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06795 HW43_RS06800 HW43_06645 HW43_RS06800 1397113 1397331 + hypothetical protein gene gene1358 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06800 HW43_RS06805 HW43_06650 entF entF 1397328 1401209 + enterobactin synthase subunit F with EntB%2C EntD%2C and EntE forms the multienzyme complex enterobactin synthase%3B EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin gene gene1359 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06805 HW43_RS06810 HW43_06655 HW43_RS06810 1401425 1402558 + hypothetical protein in Salmonella is responsible for long O-antigen polymerization%3B may be part of the ferric enterobactin transport system%3B necessary for enetrobactin uptake gene gene1360 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06810 HW43_RS06815 HW43_06660 HW43_RS06815 1402555 1403370 - ferric enterobactin transport ATP-binding protein FepC with FepBDE is involved in the transport of ferric enterobactin gene gene1361 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06815 HW43_RS06820 HW43_06665 HW43_RS06820 1403367 1404359 - ferric anguibactin ABC transporter permease with FepBCD is involved in the transport of ferric enterobactin gene gene1362 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06820 HW43_RS06825 HW43_06670 HW43_RS06825 1404356 1405360 - iron-enterobactin transporter membrane protein with FepBCG is involved in the transport of ferric enterobactin gene gene1363 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06825 HW43_RS06830 HW43_06675 HW43_RS06830 1405471 1406721 + enterobactin exporter EntS protein p43%3B inner membrane protein that exports enterobactin to the periplasmic space%3B member of the major facilitator superfamily (MFS) of transporters gene gene1364 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06830 HW43_RS06835 HW43_06680 HW43_RS06835 1406725 1407681 - ferrienterobactin-binding periplasmic protein with FepCDG is involved in the transport of ferric enterobactin gene gene1365 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06835 HW43_RS06840 HW43_06685 HW43_RS06840 1407870 1409045 + isochorismate synthase EntC gene gene1366 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06840 HW43_RS06845 HW43_06690 entE entE 1409055 1410665 + enterobactin synthase subunit E bifunctional 2%2C3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase%3B activates the carboxylate group of 2%2C3-dihydroxy-benzoate forming (2%2C3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2%2C3-dihydroxy-benzoate adenylate gene gene1367 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06845 HW43_RS06850 HW43_06695 HW43_RS06850 1410679 1411536 + enterobactin synthase component B 2%2C3 dihydro-2%2C3 dihydroxybenzoate synthase%3B catalyzes the formation of 2%2C3 dihydro-2%2C3 dihydroxybenzoate and pyruvate from isochorismate%3B with Ent DEF is involved in enterobactin synthesis gene gene1368 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06850 HW43_RS06855 HW43_06700 HW43_RS06855 1411536 1412282 + 2%2C3-dihydro-2%2C3-dihydroxybenzoate dehydrogenase catalyzes the formation of 2%2C3-dihydroxybenzoate from 2%2C3-dihydro-2%2C3-dihydroxybenzoate%3B involved in the biosynthesis of siderophores%2C enterobactin%2C bacillibactin or vibriobactin gene gene1369 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06855 HW43_RS06860 HW43_06705 HW43_RS06860 1412285 1412698 + proofreading thioesterase EntH required for efficient enterobactin production gene gene1370 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06860 HW43_RS06865 HW43_06710 HW43_RS06865 1412879 1414984 + carbon starvation protein A gene gene1371 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06865 HW43_RS06870 HW43_06715 HW43_RS06870 1415166 1415363 + hypothetical protein gene gene1372 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06870 HW43_RS06875 HW43_06720 HW43_RS06875 1415373 1416461 - oxidoreductase member of the iron-containing alcohol dehydrogenase family gene gene1373 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06875 HW43_RS06880 HW43_06725 HW43_RS06880 1416570 1417730 + aminotransferase catalyzes the transfer of an amino moiety%3B preference for methionine followed by histidine and phenylalanine gene gene1374 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06880 HW43_RS06885 HW43_06730 HW43_RS06885 1417731 1418348 - hypothetical protein gene gene1375 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06885 HW43_RS06890 HW43_06735 HW43_RS06890 1418333 1419553 - hypothetical protein gene gene1376 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06890 HW43_RS06895 HW43_06740 HW43_RS06895 1419700 1420602 - LysR family transcriptional regulator gene gene1377 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06895 HW43_RS06900 HW43_06745 dsbG dsbG 1420811 1421557 - disulfide isomerase Involved in disulfide bond formation gene gene1378 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06900 HW43_RS06905 HW43_06750 HW43_RS06905 1421929 1422492 + alkyl hydroperoxide reductase subunit C with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols%3B AhpC reduced the hydroperoxide substrate gene gene1379 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06905 HW43_RS06910 HW43_06755 HW43_RS06910 1422621 1424186 + alkyl hydroperoxide reductase subunit F gene gene1380 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06910 HW43_RS06915 HW43_06760 HW43_RS06915 1424307 1424735 - universal stress protein G interacts with GroEL%3B is induced by starvation%2C heat shock and toxic agents gene gene1381 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06915 HW43_RS06920 HW43_06765 HW43_RS06920 1424956 1426194 + oxidoreductase gene gene1382 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06920 HW43_RS06925 HW43_24780 HW43_RS06925 1426198 1426386 - hypothetical protein gene gene1383 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06925 HW43_RS06930 HW43_06775 HW43_RS06930 1426425 1426835 - nucleoside diphosphate kinase regulator Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis%2C CTP for lipid synthesis%2C and GTP for protein elongation gene gene1384 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06930 HW43_RS06935 HW43_06780 HW43_RS06935 1427065 1427871 - ribonuclease I gene gene1385 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06935 HW43_RS06940 HW43_06785 HW43_RS06940 1427985 1429448 - citrate carrier involved in the transport of citrate into the cell along with the export of succinate out of the cell gene gene1386 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06940 HW43_RS06945 HW43_06790 citG citG 1429499 1430377 - 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA gene gene1387 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06945 HW43_RS06950 HW43_06795 citX citX 1430352 1430903 - apo-citrate lyase phosphoribosyl-dephospho-CoA transferase 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase%3B holo-citrate lyase synthase%3B CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate gene gene1388 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06950 HW43_RS06955 HW43_06800 HW43_RS06955 1430907 1432439 - citrate lyase subunit alpha citrate-ACP transferase%2C the alpha subunit catalyzes the formation of (3S)-citryl-CoA from acetyl-CoA and citrate gene gene1389 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06955 HW43_RS06960 HW43_06805 HW43_RS06960 1432450 1433358 - citrate lyase subunit beta citryl-ACP lyase%3B catalyzes the formation of acetate and oxaloacetate from citrate gene gene1390 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06960 HW43_RS06965 HW43_06810 HW43_RS06965 1433355 1433651 - citrate lyase ACP gene gene1391 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06965 HW43_RS06970 HW43_06815 HW43_RS06970 1433666 1434724 - [citrate [pro-3S]-lyase] ligase activates citrate lyase by acetylation of the gamma subunit gene gene1392 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06970 HW43_RS06975 HW43_06820 dpiB dpiB 1435104 1436762 + sensor histidine kinase regulates the expression of citrate fermentation genes gene gene1393 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06975 HW43_RS06980 HW43_06825 dpiA dpiA 1436731 1437411 + transcriptional regulator regulates the expression of citrate fermentation genes gene gene1394 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06980 HW43_RS06985 HW43_06830 dcuC dcuC 1437452 1438837 - anaerobic C4-dicarboxylate transporter DcuC responsible for the transport of C4-dicarboxylates during anaerobic growth gene gene1395 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06985 HW43_RS06990 HW43_06835 pagP pagP 1439426 1439986 + lipid A palmitoyltransferase PagP catalyzes the transfer of palmitate to lipid A gene gene1396 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06990 HW43_RS06995 HW43_06840 HW43_RS06995 1440161 1440370 + cold-shock protein CspE gene gene1397 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS06995 HW43_RS07000 HW43_06845 HW43_RS07000 1440423 1440806 - camphor resistance protein CrcB camphor resistance protein CrcB%3B may be involved in chromosome condensation%3B overexpression in Escherichia coli protects against decondensation by camphor%3B overexpressing the protein results in an increase in supercoiling gene gene1398 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07000 HW43_RS07005 HW43_06850 HW43_RS07005 1440899 1441687 + hydrolase YbeM gene gene1399 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07005 HW43_RS07010 HW43_06855 tatE tatE 1441816 1442019 + preprotein translocase subunit TatE TatE%3B similar to TatA and found in some proteobacteria%3B part of system that translocates proteins with a conserved twin arginine motif across the inner membrane%3B capable of translocating folded substrates typically those with bound cofactors%3B similar to a protein import system in thylakoid membranes gene gene1400 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07010 HW43_RS07015 HW43_06860 HW43_RS07015 1442120 1443085 - lipoyl synthase catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group gene gene1401 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07015 HW43_RS07020 HW43_06865 HW43_RS07020 1443294 1444247 - LysR family transcriptional regulator gene gene1402 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07020 HW43_RS07025 HW43_24785 HW43_RS07025 1444305 1444454 + hypothetical protein gene gene1403 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07025 HW43_RS07030 HW43_06870 HW43_RS07030 1444506 1445147 - lipoyl(octanoyl) transferase lipoyl/octanoyltransferase%3B catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein gene gene1404 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07030 HW43_RS07035 HW43_06875 HW43_RS07035 1445248 1445511 - hypothetical protein gene gene1405 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07035 HW43_RS07040 HW43_06880 HW43_RS07040 1445622 1446833 - D-alanyl-D-alanine carboxypeptidase penicillin-binding protein 5%3B removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors gene gene1406 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07040 HW43_RS07045 HW43_06885 HW43_RS07045 1446972 1448060 - hypothetical protein septal ring protein%2C suppressor of prc%2C minor lipoprotein gene gene1407 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07045 HW43_RS07050 HW43_06890 HW43_RS07050 1448071 1449183 - rod shape-determining protein RodA gene gene1408 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07050 HW43_RS07055 HW43_06895 HW43_RS07055 1449186 1451087 - penicillin-binding protein 2 gene gene1409 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07055 HW43_RS07060 HW43_06900 HW43_RS07060 1451118 1451585 - ribosomal RNA large subunit methyltransferase H gene gene1410 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07060 HW43_RS07065 HW43_06905 HW43_RS07065 1451589 1451906 - ribosome silencing factor RsfS gene gene1411 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07065 HW43_RS07070 HW43_06910 HW43_RS07070 1452166 1452777 - adenosylcobalamin/alpha-ribazole phosphatase gene gene1412 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07070 HW43_RS07075 HW43_06915 HW43_RS07075 1452801 1453442 - nicotinate-nucleotide adenylyltransferase gene gene1413 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07075 HW43_RS07080 HW43_06920 holA holA 1453444 1454475 - DNA polymerase III subunit delta required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA gene gene1414 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07080 HW43_RS07085 HW43_06925 HW43_RS07085 1454475 1455056 - hypothetical protein rare lipoprotein B%3B involved in the assembly of LPS in the outer membrane gene gene1415 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07085 HW43_RS07090 HW43_06930 leuS leuS 1455071 1457653 - leucine--tRNA ligase leucine--tRNA ligase%3B LeuRS%3B class-I aminoacyl-tRNA synthetase%3B charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA%3B due to the large number of codons that tRNA(Leu) recognizes%2C the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA%2C but instead recognition is dependent on a conserved discriminator base A37 and a long arm%3B an editing domain hydrolyzes misformed products%3B in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase gene gene1416 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07090 HW43_RS07095 HW43_06935 HW43_RS07095 1457888 1458370 + hypothetical protein gene gene1417 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07095 HW43_RS07100 HW43_06940 HW43_RS07100 1458440 1459417 - hypothetical protein gene gene1418 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07100 HW43_RS07105 HW43_06945 HW43_RS07105 1459580 1460287 + hypothetical protein gene gene1419 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07105 HW43_RS07110 HW43_06950 HW43_RS07110 1460284 1461711 + molecular chaperone DnaJ gene gene1420 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07110 HW43_RS07115 HW43_06955 HW43_RS07115 1461721 1462275 - hypothetical protein gene gene1421 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07115 HW43_RS07120 HW43_06960 HW43_RS07120 1462376 1463083 + hypothetical protein gene gene1422 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07120 HW43_RS07125 HW43_06965 HW43_RS07125 1463080 1464531 + hypothetical protein gene gene1423 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07125 HW43_RS07130 HW43_06970 HW43_RS07130 1464591 1466261 - molecular chaperone HscC gene gene1424 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07130 HW43_RS07135 HW43_06975 rihA rihA 1466345 1467280 - pyrimidine-specific ribonucleoside hydrolase RihA Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil%2C respectively%3B pyrimidine-specific gene gene1425 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07135 HW43_RS07140 HW43_06980 artP artP 1467398 1468123 - glutamate/aspartate transport ATP-binding protein GltL With ArtMQJI transports arginine across the inner membrane gene gene1426 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07140 HW43_RS07145 HW43_06985 HW43_RS07145 1468123 1468797 - glutamate ABC transporter permease with GltJLPS and GadC for glutamate and GltJLP%2C DctA and DcuAB for aspartate is involved in the transport of glutamate and aspartate gene gene1427 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07145 HW43_RS07150 HW43_06990 HW43_RS07150 1468797 1469537 - glutamate ABC transporter permease with GltIKL is involved in the transport of glutamate and aspartate gene gene1428 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07150 HW43_RS07155 HW43_06995 HW43_RS07155 1469707 1470615 - amino acid transporter gene gene1429 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07155 HW43_RS07160 HW43_07000 HW43_RS07160 1471070 1472947 + hypothetical protein gene gene1430 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07160 HW43_RS07165 HW43_07005 lnt lnt 1473025 1474563 - apolipoprotein N-acyltransferase Transfers the fatty acyl group on membrane lipoproteins gene gene1431 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07165 HW43_RS07170 HW43_07010 HW43_RS07170 1474588 1475466 - magnesium and cobalt efflux protein CorC involved in the transport of magnesium and cobalt ions gene gene1432 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07170 HW43_RS07175 HW43_07015 HW43_RS07175 1475556 1476023 - endoribonuclease YbeY gene gene1433 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07175 HW43_RS07180 HW43_07020 HW43_RS07180 1476020 1477060 - phoH-like protein gene gene1434 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07180 HW43_RS07185 HW43_07025 HW43_RS07185 1477213 1478637 - tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) gene gene1435 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07185 HW43_RS07190 HW43_07030 ubiF ubiF 1478783 1479958 + 2-octaprenyl-3-methyl-6-methoxy-1%2C4-benzoquinol hydroxylase catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1%2C4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1%2C4-benzoquinol%3B functions in the biosynthesis of ubiquinone or coenzyme Q gene gene1436 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07190 HW43_RS07195 HW43_07040 HW43_RS07195 1480112 1480186 - tRNA-Gln tRNA gene1437 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07195 HW43_RS07200 HW43_07045 HW43_RS07200 1480224 1480298 - tRNA-Gln tRNA gene1438 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07200 HW43_RS07205 HW43_07050 HW43_RS07205 1480347 1480423 - tRNA-Met tRNA gene1439 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07205 HW43_RS07210 HW43_07055 HW43_RS07210 1480439 1480513 - tRNA-Gln tRNA gene1440 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07210 HW43_RS07215 HW43_07060 HW43_RS07215 1480548 1480622 - tRNA-Gln tRNA gene1441 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07215 HW43_RS07220 HW43_07065 HW43_RS07220 1480646 1480730 - tRNA-Leu tRNA gene1442 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07220 HW43_RS07225 HW43_07070 HW43_RS07225 1480739 1480815 - tRNA-Met tRNA gene1443 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07225 HW43_RS07230 HW43_07075 asnB asnB 1481196 1482860 - asparagine synthetase B functions in asparagine biosynthesis%3B converts glutamine%2C aspartate%2C ATP%2C and water to glutamate%2C asparagine%2C pyrophosphate and AMP gene gene1444 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07230 HW43_RS07235 HW43_07080 HW43_RS07235 1483117 1483869 - ribonucleotide monophosphatase NagD gene gene1445 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07235 HW43_RS07240 HW43_07085 HW43_RS07240 1483917 1485137 - N-acetylglucosamine repressor regulates the synthesis of glucosamine and N-acetylglucosamine by acting as a repressor of the nagEBACD operon and both a repressor and activator of the glmSU operon gene gene1446 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07240 HW43_RS07245 HW43_07090 nagA nagA 1485146 1486294 - N-acetylglucosamine-6-phosphate deacetylase catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate gene gene1447 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07245 HW43_RS07250 HW43_07095 nagB nagB 1486354 1487154 - glucosamine-6-phosphate deaminase catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate gene gene1448 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07250 HW43_RS07255 HW43_07100 HW43_RS07255 1487487 1489433 + PTS N-acetylglucosamine transporter subunit IIABC phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene1449 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07255 HW43_RS07260 HW43_07105 HW43_RS07260 1489636 1491300 + glutamine--tRNA ligase catalyzes a two-step reaction%2C first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA gene gene1450 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07260 HW43_RS07265 HW43_07115 chiP chiP 1491878 1493284 + chitoporin outer membrane porin involved in the transport of chitooligosaccharides gene gene1451 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07265 HW43_RS07270 HW43_07120 HW43_RS07270 1493334 1493660 + hypothetical protein gene gene1452 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07270 HW43_RS07275 HW43_07125 fur fur 1493745 1494191 - ferric uptake regulation protein negatively regulates a number of operons that encode enzymes involved in iron transport%3B activated by manganese%3B forms a homodimer gene gene1453 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07275 HW43_RS07280 HW43_24790 HW43_RS07280 1494184 1494270 - Fur leader peptide gene gene1454 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07280 HW43_RS07285 HW43_24795 HW43_RS07285 1494236 1494490 + hypothetical protein gene gene1455 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07285 HW43_RS07290 HW43_07130 HW43_RS07290 1494480 1495010 - flavodoxin-1 An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group gene gene1456 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07290 HW43_RS07295 HW43_07135 HW43_RS07295 1495150 1495443 - LexA-regulated protein%2C CopB family gene gene1457 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07295 HW43_RS07300 HW43_07140 HW43_RS07300 1495583 1496347 - acyl-CoA esterase gene gene1458 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07300 HW43_RS07305 HW43_07145 HW43_RS07305 1496532 1497077 + negative modulator of initiation of replication negative modulator of the initiation of chromosome replication gene gene1459 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07305 HW43_RS07310 HW43_07150 HW43_RS07310 1497103 1498743 + phosphoglucomutase catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate gene gene1460 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07310 HW43_RS07315 HW43_07155 potE potE 1498799 1500118 - putrescine-ornithine antiporter catalyzes the uptake of putrescine via a proton symport mechanism%2C as well as the efflux of putrescine by a putrescine/ornithine antiport system gene gene1461 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07315 HW43_RS07320 HW43_07160 HW43_RS07320 1500115 1502313 - ornithine decarboxylase gene gene1462 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07320 HW43_RS07325 HW43_24800 HW43_RS07325 1502847 1502981 + hypothetical protein gene gene1463 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07325 HW43_RS07330 HW43_07165 HW43_RS07330 1503003 1503680 - two-component system response regulator response regulator in two-component regulatory system with KdpD%3B regulates the kdp operon involved in potassium transport gene gene1464 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07330 HW43_RS07335 HW43_07170 HW43_RS07335 1503677 1506361 - two-component system sensor histidine kinase KdpD sensory histidine kinase in two-component regulatory system with KdpE%3B signal sensing protein gene gene1465 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07335 HW43_RS07340 HW43_07175 HW43_RS07340 1506354 1506926 - potassium-transporting ATPase C chain One of the components of the high-affinity ATP-driven potassium transport (or KDP)system%2C which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex gene gene1466 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07340 HW43_RS07345 HW43_07180 HW43_RS07345 1506935 1508983 - potassium-transporting ATPase B chain One of the components of the high-affinity ATP-driven potassium transport (or KDP) system%2C which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions gene gene1467 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07345 HW43_RS07350 HW43_07185 HW43_RS07350 1509006 1510679 - potassium-transporting ATPase A chain catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions gene gene1468 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07350 HW43_RS07355 HW43_24805 kdpF kdpF 1510679 1510768 - protein KdpF one of the components of the high-affinity ATP-driven potassium transport (or KDP) system%2C which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions gene gene1469 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07355 HW43_RS07360 HW43_07195 HW43_RS07360 1511081 1511287 + DUF2517 domain-containing protein gene gene1470 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07360 HW43_RS07365 HW43_07200 HW43_RS07365 1511530 1515723 + RHS element protein RhsA gene gene1471 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07365 HW43_RS07370 HW43_07205 HW43_RS07370 1515723 1516049 + membrane protein gene gene1472 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07370 HW43_RS07375 HW43_24810 HW43_RS07375 1516167 1517600 + hypothetical protein gene gene1473 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07375 HW43_RS07380 HW43_07215 HW43_RS07380 1517904 1518167 + hypothetical protein gene gene1474 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07380 HW43_RS07385 HW43_07220 HW43_RS07385 1518393 1518647 + transposase gene gene1475 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07385 HW43_RS07390 HW43_07225 HW43_RS07390 1518866 1519534 + hypothetical protein gene gene1476 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07390 HW43_RS07395 HW43_07230 HW43_RS07395 1519682 1520191 + hypothetical protein gene gene1477 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07395 HW43_RS07400 HW43_07235 HW43_RS07400 1520188 1521606 + deoxyribodipyrimidine photolyase UV-induced DNA repair%3B converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers%3B light dependent gene gene1478 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07400 HW43_RS07405 HW43_07240 HW43_RS07405 1521648 1523129 - peptide ABC transporter permease gene gene1479 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07405 HW43_RS07410 HW43_07245 HW43_RS07410 1523400 1524143 + Nif3-like dinuclear metal center hexameric protein gene gene1480 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07410 HW43_RS07415 HW43_07250 HW43_RS07415 1524166 1524822 + hypothetical protein gene gene1481 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07415 HW43_RS07420 HW43_07255 HW43_RS07420 1524816 1525748 + hypothetical protein gene gene1482 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07420 HW43_RS07425 HW43_07260 HW43_RS07425 1525738 1526472 + LamB/YcsF family protein gene gene1483 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07425 HW43_RS07430 HW43_07265 HW43_RS07430 1526508 1527299 + endonuclease VII 5-formyluracil/5-hydroxymethyluracil DNA glycosylase%3B involved in base excision repair of DNA damaged by oxidation or by mutagenic agents%3B acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines%3B has apurinic/apyrimidinic lyase activity gene gene1484 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07430 HW43_RS07435 HW43_07270 HW43_RS07435 1527296 1528342 - AbrB family transcriptional regulator gene gene1485 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07435 HW43_RS07440 HW43_07275 HW43_RS07440 1528494 1529555 - hypothetical protein gene gene1486 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07440 HW43_RS07445 HW43_07280 HW43_RS07445 1529552 1530283 - fimbrial protein gene gene1487 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07445 HW43_RS07450 HW43_07285 HW43_RS07450 1530298 1532748 - membrane protein gene gene1488 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07450 HW43_RS07455 HW43_07290 HW43_RS07455 1532808 1533374 - fimbrial protein gene gene1489 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07455 HW43_RS07460 HW43_07295 gltA gltA 1533765 1535048 - citrate synthase type II enzyme%3B in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate%3B allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation%3B forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A%3B functions in TCA cycle%2C glyoxylate cycle and respiration%3B enzyme from Helicobacter pylori is not inhibited by NADH gene gene1490 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07460 HW43_RS07465 HW43_24815 HW43_RS07465 1535036 1535221 + citrate synthase gene gene1491 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07465 HW43_RS07470 HW43_07300 sdhC sdhC 1535742 1536146 + succinate dehydrogenase cytochrome b556 large membrane subunit gene gene1492 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07470 HW43_RS07475 HW43_07305 sdhD sdhD 1536140 1536487 + succinate dehydrogenase hydrophobic membrane anchor subunit gene gene1493 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07475 HW43_RS07480 HW43_07310 sdhA sdhA 1536487 1538253 + succinate dehydrogenase flavoprotein subunit part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers)%3B SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556%3B SdhC binds ubiquinone%3B oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol gene gene1494 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07480 HW43_RS07485 HW43_07315 sdhB sdhB 1538269 1538985 + succinate dehydrogenase iron-sulfur subunit part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers)%3B SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556%3B SdhC binds ubiquinone%3B oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol%3B the catalytic subunits are similar to fumarate reductase gene gene1495 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07485 HW43_RS07490 HW43_24820 HW43_RS07490 1539007 1539204 + hypothetical protein gene gene1496 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07490 HW43_RS07495 HW43_07320 HW43_RS07495 1539186 1541987 + 2-oxoglutarate dehydrogenase E1 component gene gene1497 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07495 HW43_RS07500 HW43_07325 HW43_RS07500 1542002 1543219 + dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex component of 2-oxoglutarate dehydrogenase complex%3B catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA gene gene1498 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07500 HW43_RS07505 HW43_07330 sucC sucC 1543313 1544479 + succinyl-CoA ligase subunit beta catalyzes the interconversion of succinyl-CoA and succinate gene gene1499 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07505 HW43_RS07510 HW43_07335 HW43_RS07510 1544479 1545348 + succinyl-CoA ligase subunit alpha Catalyzes the only substrate-level phosphorylation in the TCA cycle gene gene1500 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07510 HW43_RS07515 HW43_07340 HW43_RS07515 1545452 1546174 - XRE family transcriptional regulator regulates the succiny-lCoA synthetase operon gene gene1501 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07515 HW43_RS07520 HW43_07345 HW43_RS07520 1546343 1548259 + PTS 2-O-a-mannosyl-D-glycerate transporter subunit IIABC involved in the phosphorylation and transport of sugars across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene1502 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07520 HW43_RS07525 HW43_07350 HW43_RS07525 1548277 1550910 + alpha-mannosidase gene gene1503 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07525 HW43_RS07530 HW43_07355 HW43_RS07530 1550935 1551162 + hypothetical protein gene gene1504 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07530 HW43_RS07535 HW43_07360 HW43_RS07535 1551757 1553325 + cytochrome bd-I ubiquinol oxidase subunit 1 part of the aerobic respiratory chain%3B catalyzes the ubiquinol to ubiquinone gene gene1505 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07535 HW43_RS07540 HW43_07365 HW43_RS07540 1553341 1554480 + cytochrome bd-I ubiquinol oxidase subunit 2 gene gene1506 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07540 HW43_RS07545 HW43_24825 HW43_RS07545 1554495 1554608 + cytochrome bd-I ubiquinol oxidase subunit X gene gene1507 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07545 HW43_RS07550 HW43_07375 HW43_RS07550 1554608 1554901 + cyd operon protein YbgE gene gene1508 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07550 HW43_RS07555 HW43_07380 HW43_RS07555 1555051 1555455 + acyl-CoA thioester hydrolase YbgC catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters%3B physiological role remains unknown%3B involved in phospholipid metabolism%3B part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components gene gene1509 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07555 HW43_RS07560 HW43_07385 HW43_RS07560 1555461 1556144 + colicin transporter membrane spanning protein in TolA-TolQ-TolR complex%3B involved in the tonB-independent uptake of group A colicins gene gene1510 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07560 HW43_RS07565 HW43_07390 HW43_RS07565 1556148 1556576 + protein TolR membrane spanning protein in TolA-TolQ-TolR complex%3B involved in the tonB-independent uptake of group A colicins gene gene1511 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07565 HW43_RS07570 HW43_07395 tolA tolA 1556641 1557816 + cell envelope integrity/translocation protein TolA inner membrane component of 7 member Tol-Pal envelope-spanning complex%3B involved in maintaining cell envelope integrity%3B utilized by colicins and filamentous phages for import%3B interacts with TolB%2C Pal%2C and through TolB to various outer membrane porins gene gene1512 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07570 HW43_RS07575 HW43_07400 tolB tolB 1557948 1559240 + protein TolB forms dimers%3B may be involved in cell envelope integrity%3B interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA gene gene1513 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07575 HW43_RS07580 HW43_07405 HW43_RS07580 1559275 1559796 + peptidoglycan-associated lipoprotein gene gene1514 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07580 HW43_RS07585 HW43_07410 HW43_RS07585 1559806 1560597 + tol-pal system protein YbgF periplasmic protein that interacts with TolA%3B the tol-pal system is probably involved in maintaining cell envelope integrity gene gene1515 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07585 HW43_RS07590 HW43_07415 HW43_RS07590 1560762 1560837 + tRNA-Lys tRNA gene1516 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07590 HW43_RS07595 HW43_07420 HW43_RS07595 1560973 1561048 + tRNA-Val tRNA gene1517 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07595 HW43_RS07600 HW43_07425 HW43_RS07600 1561051 1561126 + tRNA-Lys tRNA gene1518 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07600 HW43_RS07605 HW43_07430 HW43_RS07605 1561276 1561351 + tRNA-Val tRNA gene1519 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07605 HW43_RS07610 HW43_07435 HW43_RS07610 1561355 1561430 + tRNA-Lys tRNA gene1520 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07610 HW43_RS07615 HW43_07440 HW43_RS07615 1561577 1561652 + tRNA-Lys tRNA gene1521 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07615 HW43_RS07620 HW43_07445 HW43_RS07620 1561686 1561761 + tRNA-Lys tRNA gene1522 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07620 HW43_RS07625 HW43_07450 HW43_RS07625 1562010 1563053 + quinolinate synthase A 3 different subfamilies%3B catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate gene gene1523 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07625 HW43_RS07630 HW43_07455 HW43_RS07630 1563091 1563810 + nicotinamide riboside transporter PnuC involved in nicotinamide riboside transport gene gene1524 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07630 HW43_RS07635 HW43_07460 HW43_RS07635 1563807 1564748 - zinc transporter ZitB involved in zinc efflux across the cytoplasmic membrane gene gene1525 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07635 HW43_RS07640 HW43_07465 HW43_RS07640 1564862 1565242 - periplasmic protein gene gene1526 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07640 HW43_RS07645 HW43_24830 HW43_RS07645 1565337 1565450 - glutamate decarboxylase gene gene1527 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07645 HW43_RS07650 HW43_07470 HW43_RS07650 1565558 1566610 + phospho-2-dehydro-3-deoxyheptonate aldolase catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate%2C phenylalanine sensitive gene gene1528 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07650 HW43_RS07655 HW43_07475 gpmA gpmA 1566768 1567520 - 2%2C3-bisphosphoglycerate-dependent phosphoglycerate mutase 2%2C3-bisphosphoglycerate-dependent%3B catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate gene gene1529 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07655 HW43_RS07660 HW43_07480 galM galM 1567725 1568765 - aldose 1-epimerase mutarotase%3B catalyzes the conversion of beta-galactose to the alpha-anomer%3B links the metabolism of lactose and galactose gene gene1530 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07660 HW43_RS07665 HW43_07485 HW43_RS07665 1568759 1569907 - galactokinase catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism gene gene1531 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07665 HW43_RS07670 HW43_07490 HW43_RS07670 1569911 1570957 - galactose-1-phosphate uridylyltransferase catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P gene gene1532 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07670 HW43_RS07675 HW43_07495 HW43_RS07675 1570967 1571983 - UDP-galactose-4-epimerase gene gene1533 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07675 HW43_RS07680 HW43_07500 HW43_RS07680 1572244 1573716 - molybdenum ABC transporter ATP-binding protein contains 2 ATP-binding cassettes%3B involved in the transport of molybdenum gene gene1534 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07680 HW43_RS07685 HW43_07505 HW43_RS07685 1573784 1574572 - transcriptional regulator ModE represses the modABCD operon and activates the moaABCD and napFDAGHBC operons gene gene1535 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07685 HW43_RS07690 HW43_07510 HW43_RS07690 1574701 1574850 + multidrug efflux pump accessory protein AcrZ gene gene1536 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07690 HW43_RS07695 HW43_07515 modA modA 1575017 1575790 + molybdate ABC transporter substrate-binding protein with ModCB is involved in the high-affinity transport of molybdate gene gene1537 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07695 HW43_RS07700 HW43_07520 modB modB 1575790 1576479 + molybdenum ABC transporter permease part of ModCBA molybdate transporter%3B member of ABC superfamily%3B inner membrane component%3B regulated by repressor protein ModE gene gene1538 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07700 HW43_RS07705 HW43_07525 modC modC 1576482 1577540 + molybdenum import ATP-binding protein ModC Part of the ABC transporter complex modABC involved in molybdenum import gene gene1539 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07705 HW43_RS07710 HW43_07530 HW43_RS07710 1577541 1578359 - pyridoxal phosphate phosphatase gene gene1540 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07710 HW43_RS07715 HW43_24835 HW43_RS07715 1578514 1579509 + 6-phosphogluconolactonase catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate gene gene1541 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07715 HW43_RS07720 HW43_07540 HW43_RS07720 1579550 1580503 - LysR family transcriptional regulator gene gene1542 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07720 HW43_RS07725 HW43_07550 HW43_RS07725 1580687 1581739 + PrpF family isomerase gene gene1543 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07725 HW43_RS07730 HW43_07555 HW43_RS07730 1581815 1583248 + membrane protein gene gene1544 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07730 HW43_RS07735 HW43_07560 HW43_RS07735 1583431 1585692 + hydratase gene gene1545 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07735 HW43_RS07740 HW43_07565 HW43_RS07740 1585926 1587209 - acyl-CoA thioesterase gene gene1546 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07740 HW43_RS07745 HW43_07570 HW43_RS07745 1587361 1587837 - kinase inhibitor homolog%2C UPF0098 family YbhB%3B similar to rat and human kinase inhibitory proteins gene gene1547 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07745 HW43_RS07750 HW43_07575 HW43_RS07750 1587896 1589128 - adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7%2C8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate gene gene1548 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07750 HW43_RS07755 HW43_07580 HW43_RS07755 1589272 1590312 + biotin synthase catalyzes the formation of biotin from dethiobiotin gene gene1549 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07755 HW43_RS07760 HW43_07585 HW43_RS07760 1590309 1591463 + 8-amino-7-oxononanoate synthase catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine gene gene1550 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07760 HW43_RS07765 HW43_07590 HW43_RS07765 1591450 1592205 + malonyl-[acyl-carrier protein] O-methyltransferase BioC methyltransferase%3B acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA%2C a biotin precursor%3B member of the bio operon (bioABFCD)%3B in Escherichia coli%2C bioC-null mutants require biotin for growth gene gene1551 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07765 HW43_RS07770 HW43_07595 bioD bioD 1592198 1592875 + dithiobiotin synthetase DTB synthetase%3B dethiobiotin synthase%3B involved in production of dethiobiotin from ATP and 7%2C8-diaminononanoate and carbon dioxide%3B contains magnesium gene gene1552 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07770 HW43_RS07775 HW43_07600 HW43_RS07775 1593454 1595475 + UvrABC system protein B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands%2C where it probes for the presence of a lesion gene gene1553 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07775 HW43_RS07780 HW43_07605 HW43_RS07780 1595667 1596575 - hypothetical protein gene gene1554 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07780 HW43_RS07785 HW43_24840 HW43_RS07785 1596818 1596973 - hypothetical protein gene gene1555 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07785 HW43_RS07790 HW43_07610 moaA moaA 1596972 1597961 + cyclic pyranopterin monophosphate synthase together with moaC%2C is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z gene gene1556 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07790 HW43_RS07795 HW43_07615 HW43_RS07795 1597983 1598495 + molybdenum cofactor biosynthesis protein B gene gene1557 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07795 HW43_RS07800 HW43_07620 moaC moaC 1598498 1598983 + cyclic pyranopterin monophosphate synthase accessory protein MoaC%3B along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z%3B involved in molybdenum cofactor biosynthesis gene gene1558 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07800 HW43_RS07805 HW43_07625 moaD moaD 1598976 1599221 + molybdopterin synthase sulfur carrier subunit catalyzes the conversion of molybdopterin precursor Z into molybdopterin gene gene1559 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07805 HW43_RS07810 HW43_07630 moaE moaE 1599223 1599675 + molybdopterin guanine dinucleotide biosynthesis protein MoaE catalyzes the conversion of molybdopterin precursor Z into molybdopterin gene gene1560 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07810 HW43_RS07815 HW43_07635 HW43_RS07815 1599812 1600516 + hypothetical protein gene gene1561 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07815 HW43_RS07820 HW43_07640 HW43_RS07820 1600963 1601184 - hypothetical protein gene gene1562 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07820 HW43_RS07825 HW43_07645 HW43_RS07825 1601435 1602148 + hypothetical protein gene gene1563 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07825 HW43_RS07830 HW43_07650 HW43_RS07830 1602184 1603140 - hypothetical protein gene gene1564 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07830 HW43_RS07835 HW43_07655 HW43_RS07835 1603140 1604381 - cardiolipin synthase B gene gene1565 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07835 HW43_RS07840 HW43_07660 HW43_RS07840 1604378 1605139 - hypothetical protein gene gene1566 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07840 HW43_RS07845 HW43_07665 HW43_RS07845 1605272 1605682 + hypothetical protein gene gene1567 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07845 HW43_RS07850 HW43_07670 HW43_RS07850 1605644 1606750 - inner membrane transport permease YbhR gene gene1568 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07850 HW43_RS07855 HW43_07675 HW43_RS07855 1606761 1607894 - membrane protein gene gene1569 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07855 HW43_RS07860 HW43_07680 HW43_RS07860 1607887 1609623 - ABC transporter ATP-binding protein gene gene1570 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07860 HW43_RS07865 HW43_07685 HW43_RS07865 1609616 1610611 - transporter gene gene1571 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07865 HW43_RS07870 HW43_07690 HW43_RS07870 1610614 1611285 - DUF1956 domain-containing tetR family transcriptional regulator gene gene1572 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07870 HW43_RS07875 HW43_07695 HW43_RS07875 1611514 1612878 + ATP-dependent RNA helicase RhlE this helicase is not essential cell growth gene gene1573 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07875 HW43_RS07880 HW43_07700 HW43_RS07880 1613110 1613559 - swarming motility protein gene gene1574 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07880 HW43_RS07885 HW43_07705 dinG dinG 1613712 1615862 + ATP-dependent DNA helicase DinG helicase involved in DNA repair and perhaps also replication gene gene1575 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07885 HW43_RS07890 HW43_07710 HW43_RS07890 1615890 1616852 + family 3 glycosyltransferase gene gene1576 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07890 HW43_RS07895 HW43_07715 HW43_RS07895 1616993 1618078 + dehydrogenase gene gene1577 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07895 HW43_RS07900 HW43_07720 HW43_RS07900 1618307 1618567 - hypothetical protein gene gene1578 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07900 HW43_RS07905 HW43_07725 HW43_RS07905 1618832 1619098 - RNA polymerase-binding protein DksA gene gene1579 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07905 HW43_RS07910 HW43_07730 HW43_RS07910 1619172 1619849 - PKHD-type hydroxylase gene gene1580 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07910 HW43_RS07915 HW43_24845 HW43_RS07915 1619891 1622173 - catecholate siderophore receptor Fiu Fiu%3B YbiL%3B porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine%2C dihydroxybenzoate) and beta lactam agents%3B Fiu interacts with TonB which provides the energy required for transport across the outer membrane%3B acts as a receptor for iron-siderophores and microcins E492%2C M%2C and H47%3B outer membrane protein gene gene1581 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07915 HW43_RS07920 HW43_07740 HW43_RS07920 1622438 1622698 - colanic acid mucoidy stimulation protein gene gene1582 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07920 HW43_RS07925 HW43_07745 HW43_RS07925 1622974 1623900 + ribosomal RNA large subunit methyltransferase F gene gene1583 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07925 HW43_RS07930 HW43_07750 HW43_RS07930 1623897 1626122 - moderate conductance mechanosensitive channel YbiO gene gene1584 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07930 HW43_RS07935 HW43_24850 HW43_RS07935 1626121 1626222 + hypothetical protein gene gene1585 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07935 HW43_RS07940 HW43_07760 glnQ glnQ 1626239 1626961 - glutamine ABC transporter ATP-binding protein similar to ATP-binding component of ABC transporters gene gene1586 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07940 HW43_RS07945 HW43_07765 glnP glnP 1626958 1627617 - glutamine ABC transporter permease similar to permease component of ABC transporters%3B mutations impair ability of Escherichia coli to transport and utilize glutamine gene gene1587 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07945 HW43_RS07950 HW43_07770 glnH glnH 1627756 1628502 - glutamine-binding periplasmic protein similar to periplasmic-binding component of ABC transporters gene gene1588 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07950 HW43_RS07955 HW43_24855 HW43_RS07955 1628548 1628841 - hypothetical protein gene gene1589 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07955 HW43_RS07960 HW43_07775 HW43_RS07960 1628906 1629409 - DNA protection during starvation protein binds DNA in a non-sequence-specific manner and is abundant during stationary phase%3B forms a DNA-protein crystal that protects DNA from damage%3B required for normal starvation response and long-term stationary viability%3B forms a homododecameric complex and sequesters iron which provides protection against oxidative damage gene gene1590 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07960 HW43_RS07965 HW43_07780 HW43_RS07965 1629708 1630595 - threonine transporter RhtB gene gene1591 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07965 HW43_RS07970 HW43_07785 ompX ompX 1630948 1631463 + outer membrane protein X OmpX%3B involved in cell adhesion%3B forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface%3B mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains gene gene1592 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07970 HW43_RS07975 HW43_07790 HW43_RS07975 1631512 1633095 - phosphoethanolamine transferase gene gene1593 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07975 HW43_RS07980 HW43_24860 HW43_RS07980 1633367 1633495 - small protein MntS gene gene1594 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07980 HW43_RS07985 HW43_07800 HW43_RS07985 1633681 1634148 + transcriptional regulator MntR Transcriptional regulator that represses the manganese transporter MntH when manganese is present gene gene1595 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07985 HW43_RS07990 HW43_07805 HW43_RS07990 1634145 1635263 + transporter gene gene1596 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07990 HW43_RS07995 HW43_07810 HW43_RS07995 1635322 1636242 - transpeptidase gene gene1597 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS07995 HW43_RS08000 HW43_07815 HW43_RS08000 1636461 1638053 + ABC transporter ATP-binding protein gene gene1598 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08000 HW43_RS08005 HW43_07820 HW43_RS08005 1638332 1639312 + transposase gene gene1599 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08005 HW43_RS08010 HW43_07825 HW43_RS08010 1639568 1640833 - DUF1479 domain-containing protein gene gene1600 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08010 HW43_RS08015 HW43_07830 HW43_RS08015 1640985 1641800 - hydrolase gene gene1601 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08015 HW43_RS08020 HW43_07835 HW43_RS08020 1641946 1644378 - formate acetyltransferase gene gene1602 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08020 HW43_RS08025 HW43_07840 HW43_RS08025 1644384 1645283 - pyruvate formate lyase activating enzyme gene gene1603 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08025 HW43_RS08030 HW43_07845 HW43_RS08030 1645414 1646076 + fructose-6-phosphate aldolase similar to transaldolase from Escherichia coli%3B many organisms have multiple copies gene gene1604 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08030 HW43_RS08035 HW43_07850 HW43_RS08035 1646255 1647004 - molybdopterin-synthase adenylyltransferase gene gene1605 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08035 HW43_RS08040 HW43_07855 HW43_RS08040 1647004 1648239 - molybdopterin biosynthesis protein MoeA is involved in the formation of active molybdenum cofactor and the chelation of molybdenum gene gene1606 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08040 HW43_RS08045 HW43_07860 HW43_RS08045 1648443 1649408 + isoaspartyl peptidase gene gene1607 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08045 HW43_RS08050 HW43_24865 HW43_RS08050 1649395 1651266 + glutathione import ATP-binding protein GsiA with GsiBCD is involved in glutathione import%3B GsiA contains 2 ATP-binding domains gene gene1608 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08050 HW43_RS08055 HW43_07870 HW43_RS08055 1651286 1652824 + glutathione-binding protein GsiB with GsiACD is involved in the transport of glutathione into the cell gene gene1609 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08055 HW43_RS08060 HW43_07875 HW43_RS08060 1652842 1653762 + glutathione ABC transporter permease with GsiABD is involved in the transport of glutathione into the cell gene gene1610 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08060 HW43_RS08065 HW43_07880 HW43_RS08065 1653765 1654676 + glutathione ABC transporter permease with GsiABD is involved in the transport of glutathione into the cell gene gene1611 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08065 HW43_RS08070 HW43_07885 HW43_RS08070 1654854 1657202 + cyclic di-GMP phosphodiesterase gene gene1612 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08070 HW43_RS08075 HW43_07890 HW43_RS08075 1657210 1658538 + hypothetical protein gene gene1613 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08075 HW43_RS08080 HW43_07895 rimO rimO 1658585 1659910 - ribosomal protein S12 methylthiotransferase RimO catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit gene gene1614 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08080 HW43_RS08085 HW43_07900 bssR bssR 1660123 1660506 + biofilm regulator BssR BssS%3B regulator of biofilm through signal secretion%3B disruption of this gene in Escherichia coli led to effects on biofilm formation%2C alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing gene gene1615 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08085 HW43_RS08090 HW43_07905 HW43_RS08090 1660617 1661732 + aldose dehydrogenase gene gene1616 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08090 HW43_RS08095 HW43_07910 HW43_RS08095 1661729 1662355 - glutathione S-transferase gene gene1617 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08095 HW43_RS08100 HW43_07915 HW43_RS08100 1662602 1663804 + D-alanyl-D-alanine carboxypeptidase gene gene1618 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08100 HW43_RS08105 HW43_07920 HW43_RS08105 1663851 1664609 - DeoR family transcriptional regulator gene gene1619 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08105 HW43_RS08110 HW43_07925 HW43_RS08110 1664667 1665263 - UDP pyrophosphate phosphatase gene gene1620 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08110 HW43_RS08115 HW43_07930 HW43_RS08115 1665548 1666780 + multidrug transporter MdfA gene gene1621 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08115 HW43_RS08120 HW43_07935 HW43_RS08120 1666821 1667099 - hypothetical protein gene gene1622 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08120 HW43_RS08125 HW43_07940 HW43_RS08125 1667191 1668006 - sugar phosphatase SupH gene gene1623 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08125 HW43_RS08130 HW43_07945 HW43_RS08130 1668006 1669214 - hypothetical protein gene gene1624 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08130 HW43_RS08135 HW43_07950 HW43_RS08135 1669298 1669834 + DNA-binding transcriptional regulator gene gene1625 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08135 HW43_RS08140 HW43_07955 HW43_RS08140 1670009 1671694 - transporter gene gene1626 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08140 HW43_RS08145 HW43_07960 HW43_RS08145 1671964 1672341 + hypothetical protein gene gene1627 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08145 HW43_RS08150 HW43_07965 HW43_RS08150 1672371 1672628 - glutaredoxin functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase%3B also involved in reducing some disulfides in a coupled system with glutathione reductase gene gene1628 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08150 HW43_RS08155 HW43_07970 HW43_RS08155 1672788 1673075 + DUF1418 domain-containing protein YbjC%3B located in the same operon as the nfsA gene%3B member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress%3B induced by paraquat%3B regulated by SoxS%3B unknown function gene gene1629 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08155 HW43_RS08160 HW43_07975 HW43_RS08160 1673059 1673781 + nitroreductase A NADPH-dependent%3B oxygen-insensitive%3B catalyzes the reduction of nitroaromatic compounds gene gene1630 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08160 HW43_RS08165 HW43_07980 HW43_RS08165 1673842 1674744 + ribosomal protein S6--L-glutamate ligase responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 gene gene1631 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08165 HW43_RS08170 HW43_07985 HW43_RS08170 1674832 1675308 + negative regulator of motility%3B multicopy suppressor of coaA(Ts) gene gene1632 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08170 HW43_RS08175 HW43_24870 HW43_RS08175 1675514 1675675 + putrescine/spermidine ABC transporter substrate-binding protein gene gene1633 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08175 HW43_RS08180 HW43_07990 HW43_RS08180 1675659 1676771 + putrescine-binding periplasmic protein gene gene1634 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08180 HW43_RS08185 HW43_07995 potG potG 1676866 1677999 + putrescine ABC transporter ATP-binding protein part of the PotFGHI ATP-dependent putrescine transporter gene gene1635 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08185 HW43_RS08190 HW43_08000 HW43_RS08190 1678009 1678962 + putrescine ABC transporter permease gene gene1636 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08190 HW43_RS08195 HW43_08005 HW43_RS08195 1678959 1679804 + spermidine/putrescine ABC transporter permease gene gene1637 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08195 HW43_RS08200 HW43_08010 HW43_RS08200 1679864 1680352 + hypothetical protein gene gene1638 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08200 HW43_RS08205 HW43_08015 rumB rumB 1680393 1681520 + 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC RNA uridine methyltransferase B%3B catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA gene gene1639 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08205 HW43_RS08210 HW43_08020 HW43_RS08210 1681695 1682426 - arginine/ornithine ABC transporter substrate-binding protein with ArtPMQI is involved in arginine transport gene gene1640 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08210 HW43_RS08215 HW43_08025 artM artM 1682718 1683386 - arginine transporter permease subunit ArtM with ArtPQJI acts to transport arginine across the inner membrane gene gene1641 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08215 HW43_RS08220 HW43_08030 HW43_RS08220 1683386 1684102 - arginine ABC transporter permease ArtQ with ArtPMJI transports arginine across the inner membrane gene gene1642 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08220 HW43_RS08225 HW43_08035 HW43_RS08225 1684109 1684840 - arginine ABC transporter substrate-binding protein with ArtPMQI is involved in arginine transport gene gene1643 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08225 HW43_RS08230 HW43_08040 HW43_RS08230 1684858 1685586 - arginine transport ATP-binding protein ArtP gene gene1644 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08230 HW43_RS08235 HW43_08045 HW43_RS08235 1685804 1686319 - lipoprotein induced during stationary phase and by acivicin (a glutamine analog)%3B regulated by Lrp and RpoS gene gene1645 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08235 HW43_RS08240 HW43_08050 HW43_RS08240 1686445 1686768 + hypothetical protein gene gene1646 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08240 HW43_RS08245 HW43_08055 HW43_RS08245 1686765 1687595 + N-acetylmuramoyl-L-alanine amidase catalyzes the cleavage of the bond between muamic acid and l-alanine gene gene1647 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08245 HW43_RS08250 HW43_08060 HW43_RS08250 1687592 1688605 - NAD(P)H-dependent oxidoreductase gene gene1648 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08250 HW43_RS08255 HW43_08065 HW43_RS08255 1688704 1690134 - NAD-dependent oxidoreductase gene gene1649 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08255 HW43_RS08260 HW43_08070 HW43_RS08260 1690145 1691146 - low specificity L-threonine aldolase low- specificity%3B catalyzes the formation of acetaldehyde and glycine from L-threonine%3B acts on L-threonine%2C L-allo-threonine%2C L-threo-phenylserine%2C and L-erythro-phenylserine gene gene1650 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08260 HW43_RS08265 HW43_08075 HW43_RS08265 1691183 1692901 - pyruvate dehydrogenase catalyzes the formation of acetate from pyruvate gene gene1651 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08265 HW43_RS08270 HW43_08080 HW43_RS08270 1693034 1694002 - NADH oxidoreductase HCR gene gene1652 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08270 HW43_RS08275 HW43_08085 HW43_RS08275 1694014 1695666 - hydroxylamine reductase gene gene1653 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08275 HW43_RS08280 HW43_08090 HW43_RS08280 1695810 1696709 - transporter gene gene1654 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08280 HW43_RS08285 HW43_08095 HW43_RS08285 1697166 1697861 - aquaporin Z porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure gene gene1655 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08285 HW43_RS08290 HW43_24875 HW43_RS08290 1698074 1698229 - hypothetical protein gene gene1656 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08290 HW43_RS08295 HW43_08100 HW43_RS08295 1698287 1699945 + hypothetical protein gene gene1657 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08295 HW43_RS08300 HW43_08105 HW43_RS08300 1699942 1700934 - hypothetical protein gene gene1658 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08300 HW43_RS08305 HW43_08110 HW43_RS08305 1701049 1702164 + MacA family efflux pump subunit confers macrolide resistance via active drug efflux gene gene1659 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08305 HW43_RS08310 HW43_08115 HW43_RS08310 1702161 1704107 + MacB family efflux pump subunit with MacA is involved in the export of macrolide gene gene1660 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08310 HW43_RS08315 HW43_08120 HW43_RS08315 1704180 1704404 - cold-shock protein CspD inhibits DNA replication at both initiation and elongation steps%3B stationary phase and starvation inducible gene gene1661 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08315 HW43_RS08320 HW43_08125 clpS clpS 1704727 1705047 + ATP-dependent Clp protease adapter protein ClpS involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation%3B binds to the N-terminal domain of the chaperone ClpA gene gene1662 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08320 HW43_RS08325 HW43_08130 clpA clpA 1705078 1707354 + ATP-dependent Clp protease ATP-binding subunit ClpA ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease%3B directs protease to specific substrates gene gene1663 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08325 HW43_RS08330 HW43_08135 HW43_RS08330 1707698 1707785 - tRNA-Ser tRNA gene1664 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08330 HW43_RS08335 HW43_08140 HW43_RS08335 1708039 1708257 - translation initiation factor IF-1 gene gene1665 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08335 HW43_RS08340 HW43_08145 aat aat 1708542 1709246 - leucyl/phenylalanyl-tRNA--protein transferase leucyltransferase%3B phenylalanyltransferse%3B functions in the N-end rule pathway%3B transfers Leu%2C Phe%2C Met%2C from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys gene gene1666 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08340 HW43_RS08345 HW43_08150 HW43_RS08345 1709288 1711009 - glutathione ABC transporter ATP-binding protein in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance%3B important for cytochrome bd and c gene gene1667 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08345 HW43_RS08350 HW43_08155 HW43_RS08350 1711010 1712776 - ATP-binding/permease CydD in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance%3B important for cytochrome bd and c gene gene1668 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08350 HW43_RS08355 HW43_08160 HW43_RS08355 1712899 1713864 - thioredoxin reductase catalyzes the transfer of electrons from NADPH to thioredoxin%3B FAD/NAD(P) binding gene gene1669 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08355 HW43_RS08360 HW43_08165 HW43_RS08360 1714409 1714903 + leucine-responsive regulatory protein mediates a global response to leucine%3B acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system gene gene1670 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08360 HW43_RS08365 HW43_08170 HW43_RS08365 1715038 1719105 + cell division protein FtsK DNA-binding membrane protein required for chromosome resolution and partitioning gene gene1671 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08365 HW43_RS08370 HW43_08175 lolA lolA 1719260 1719871 + outer membrane lipoprotein carrier protein LolA participates with LolB in the incorporation of lipoprotein into the outer membrane gene gene1672 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08370 HW43_RS08375 HW43_08180 HW43_RS08375 1719882 1721225 + replication-associated recombination protein A gene gene1673 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08375 HW43_RS08380 HW43_08185 HW43_RS08380 1721316 1722608 + serine--tRNA ligase gene gene1674 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08380 HW43_RS08385 HW43_08190 HW43_RS08385 1722847 1725291 + dimethyl sulfoxide reductase subunit A gene gene1675 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08385 HW43_RS08390 HW43_08195 HW43_RS08390 1725302 1725919 + dimethyl sulfoxide reductase subunit B oxidoreductase%2C Fe-S subunit%3B terminal electron transfer protein for the reduction of DMSO gene gene1676 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08390 HW43_RS08395 HW43_08200 HW43_RS08395 1725921 1726784 + dimethyl sulfoxide reductase subunit C gene gene1677 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08395 HW43_RS08400 HW43_08205 HW43_RS08400 1726820 1727446 - hypothetical protein gene gene1678 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08400 HW43_RS08405 HW43_08210 HW43_RS08405 1727761 1728909 + MFS transporter gene gene1679 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08405 HW43_RS08410 HW43_08215 HW43_RS08410 1729119 1730549 + inner membrane transporter YcaM gene gene1680 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08410 HW43_RS08415 HW43_08220 HW43_RS08415 1730550 1731458 - LysR family transcriptional regulator gene gene1681 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08415 HW43_RS08420 HW43_08225 HW43_RS08420 1731558 1732148 + hypothetical protein gene gene1682 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08420 HW43_RS08425 HW43_08230 pflA pflA 1732230 1732970 - pyruvate formate-lyase 1-activating enzyme activates pyruvate formate-lyase 1 under anaerobic conditions gene gene1683 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08425 HW43_RS08430 HW43_08235 HW43_RS08430 1733162 1735444 - formate acetyltransferase 1 formate acetyltransferase%3B catalyzes the formation of formate and acetyl-CoA from pyruvate gene gene1684 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08430 HW43_RS08435 HW43_08240 HW43_RS08435 1735499 1736356 - formate transporter FocA gene gene1685 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08435 HW43_RS08440 HW43_08245 HW43_RS08440 1736762 1738522 - hypothetical protein gene gene1686 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08440 HW43_RS08445 HW43_08250 HW43_RS08445 1738652 1739344 + UPF0702 family inner membrane protein gene gene1687 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08445 HW43_RS08450 HW43_08255 HW43_RS08450 1739543 1740631 + phosphoserine aminotransferase catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate%3B catalyzes 4 phosphohydroxy L-threonine from 2-oxo 3 hydroxy 4- phosphobutanoate%3B required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine gene gene1688 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08450 HW43_RS08455 HW43_08260 HW43_RS08455 1740702 1741985 + 3-phosphoshikimate 1-carboxyvinyltransferase gene gene1689 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08455 HW43_RS08460 HW43_08265 HW43_RS08460 1742154 1742918 + metalloprotease gene gene1690 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08460 HW43_RS08465 HW43_08270 cmk cmk 1743091 1743774 + cytidylate kinase Catalyzes the formation of (d)CDP from ATP and (d)CMP gene gene1691 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08465 HW43_RS08470 HW43_08275 rpsA rpsA 1743885 1745558 + 30S ribosomal protein S1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit%3B autoregulates expression via a C-terminal domain%3B in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats%3B the S1 nucleic acid-binding domain is found associated with other proteins gene gene1692 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08470 HW43_RS08475 HW43_08280 ihfB ihfB 1745718 1746002 + integration host factor subunit beta This protein is one of the two subunits of integration host factor%2C a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control gene gene1693 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08475 HW43_RS08480 HW43_08285 HW43_RS08480 1746209 1748473 + competence protein ComEC gene gene1694 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08480 HW43_RS08485 HW43_08290 HW43_RS08485 1748510 1750258 + lipid A export ATP-binding/permease MsbA involved in the transport of lipid A across the inner membrane gene gene1695 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08485 HW43_RS08490 HW43_08295 lpxK lpxK 1750255 1751241 + tetraacyldisaccharide 4'-kinase transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1%2C4'-bis-phosphate gene gene1696 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08490 HW43_RS08495 HW43_08300 HW43_RS08495 1751278 1752510 + hypothetical protein gene gene1697 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08495 HW43_RS08500 HW43_08305 HW43_RS08500 1752562 1752744 + hypothetical protein gene gene1698 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08500 HW43_RS08505 HW43_08310 HW43_RS08505 1752741 1753487 + 3-deoxy-manno-octulosonate cytidylyltransferase CMP-2-keto-3-deoxyoctulosonic acid synthetase%3B catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS gene gene1699 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08505 HW43_RS08510 HW43_08315 HW43_RS08510 1753641 1754534 + protein kinase-like domain protein gene gene1700 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08510 HW43_RS08515 HW43_08320 HW43_RS08515 1754511 1755290 - membrane protein gene gene1701 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08515 HW43_RS08520 HW43_08325 HW43_RS08520 1755426 1756211 + S-adenosyl-L-methionine-dependent methyltransferase gene gene1702 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08520 HW43_RS08525 HW43_08330 HW43_RS08525 1756208 1757530 + chromosome partition protein MukF acts with MukB and MukE to condense the chromosome and allow for segregation during cell division gene gene1703 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08525 HW43_RS08530 HW43_08335 HW43_RS08530 1757511 1758215 + chromosome partition protein MukE acts with MukB and MukF to condense the chromosome and allow for segregation during cell division gene gene1704 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08530 HW43_RS08535 HW43_08340 mukB mukB 1758215 1762675 + chromosome partition protein MukB SMC (structural maintenance of chromosomes) family of proteins%3B involved in chromosome condensatin and partitioning%3B forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ%3B mutations result in cell division defects gene gene1705 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08535 HW43_RS08540 HW43_08345 HW43_RS08540 1762935 1764782 + murein transpeptidase catalyzes the formation of a meso-diaminopimelyl- meso-diaminopimelyl crosslink gene gene1706 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08540 HW43_RS08545 HW43_08350 HW43_RS08545 1764963 1765511 + M15A protease-related family periplasmic protein gene gene1707 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08545 HW43_RS08550 HW43_08355 HW43_RS08550 1765538 1766185 + hypothetical protein gene gene1708 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08550 HW43_RS08555 HW43_08360 HW43_RS08555 1766407 1767597 - aspartate aminotransferase gene gene1709 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08555 HW43_RS08560 HW43_24880 HW43_RS08560 1767596 1767766 + hypothetical protein gene gene1710 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08560 HW43_RS08565 HW43_08370 HW43_RS08565 1767782 1768870 - outer membrane protein F gene gene1711 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08565 HW43_RS08570 HW43_08375 HW43_RS08570 1769472 1770872 - asparagine--tRNA ligase gene gene1712 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08570 HW43_RS08575 HW43_08380 HW43_RS08575 1771041 1772243 - nicotinate phosphoribosyltransferase catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate gene gene1713 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08575 HW43_RS08580 HW43_08385 pepN pepN 1772509 1775121 + aminopeptidase N gene gene1714 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08580 HW43_RS08585 HW43_08390 ssuB ssuB 1775328 1776095 - aliphatic sulfonate ABC transporter ATP-binding protein part of the ABC type transport system SsuABC for aliphatic sulfonates%3B with SsuA being the periplasmic substrate-binding subunit%2C SsuB the ATP-binding subunit and SsuC the permease gene gene1715 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08585 HW43_RS08590 HW43_08395 ssuC ssuC 1776092 1776883 - aliphatic sulfonate ABC transporter permease part of the ABC type transport system for alkanesulfonate SsuABC%3B SsuB the ATP-binding subunit and SsuC the permease gene gene1716 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08590 HW43_RS08595 HW43_08400 HW43_RS08595 1776894 1778039 - alkanesulfonate monooxygenase catalyzes the release of sulfite from alkanesulfonates gene gene1717 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08595 HW43_RS08600 HW43_08405 HW43_RS08600 1778036 1778995 - sulfonate ABC transporter substrate-binding protein part of the ABC type transport system SsuABC for aliphatic sulfonates%3B with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease gene gene1718 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08600 HW43_RS08605 HW43_08410 HW43_RS08605 1778988 1779563 - FMN reductase gene gene1719 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08605 HW43_RS08610 HW43_08415 HW43_RS08610 1779919 1780461 + fimbrial protein gene gene1720 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08610 HW43_RS08615 HW43_08420 HW43_RS08615 1780571 1781245 + fimbrial protein gene gene1721 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08615 HW43_RS08620 HW43_08425 HW43_RS08620 1781270 1783870 + outer membrane usher protein involved in fimbria production gene gene1722 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08620 HW43_RS08625 HW43_08430 HW43_RS08625 1783861 1784931 + fimbrial protein gene gene1723 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08625 HW43_RS08630 HW43_08435 HW43_RS08630 1785033 1785485 + fimbrial protein gene gene1724 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08630 HW43_RS08635 HW43_08440 HW43_RS08635 1785493 1786008 + fimbrial protein gene gene1725 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08635 HW43_RS08640 HW43_08445 HW43_RS08640 1786001 1786711 + fimbrial chaperone BcfG gene gene1726 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08640 HW43_RS08645 HW43_08450 HW43_RS08645 1786822 1787832 + dihydroorotate dehydrogenase catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway%3B uses a flavin nucleotide as an essential cofactor%3B class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus%2C which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors gene gene1727 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08645 HW43_RS08650 HW43_08455 HW43_RS08650 1788006 1788548 + cell division protein ZapC gene gene1728 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08650 HW43_RS08655 HW43_08460 HW43_RS08655 1788545 1789654 - hypothetical protein gene gene1729 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08655 HW43_RS08660 HW43_08465 rlmL rlmL 1789898 1792006 + 23S rRNA methyltransferase catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA gene gene1730 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08660 HW43_RS08665 HW43_08470 HW43_RS08665 1792017 1793924 + ABC transporter ATP-binding protein Uup%3B in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity%3B mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth gene gene1731 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08665 HW43_RS08670 HW43_08475 HW43_RS08670 1794054 1795307 + paraquat-inducible protein A gene gene1732 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08670 HW43_RS08675 HW43_08480 HW43_RS08675 1795312 1796952 + paraquat-inducible protein B gene gene1733 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08675 HW43_RS08680 HW43_08485 HW43_RS08680 1796949 1797512 + lipoprotein gene gene1734 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08680 HW43_RS08685 HW43_08490 HW43_RS08685 1797768 1797935 + ribosome modulation factor gene gene1735 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08685 HW43_RS08690 HW43_08495 HW43_RS08690 1798005 1798523 - 3-hydroxydecanoyl-ACP dehydratase catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2%2C3-decenoyl-ACP or 3%2C4-decenoyl-ACP gene gene1736 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08690 HW43_RS08695 HW43_08500 HW43_RS08695 1798592 1800352 - ATP-dependent protease gene gene1737 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08695 HW43_RS08700 HW43_08505 HW43_RS08700 1800538 1800990 + macrodomain Ter protein gene gene1738 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08700 HW43_RS08705 HW43_08510 HW43_RS08705 1801066 1802106 - outer membrane protein A OmpA is believed to be a porin%2C involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli%2C and it is known to play a role as a phage receptor%2C a mediator of F-factor dependent conjugation%2C and in maintaining the structural shape of the outer membrane%3B 3a%3B II*%3B G%3B d gene gene1739 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08705 HW43_RS08710 HW43_24885 HW43_RS08710 1802309 1802479 + hypothetical protein gene gene1740 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08710 HW43_RS08715 HW43_08515 HW43_RS08715 1802463 1802972 - cell division inhibitor SulA gene gene1741 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08715 HW43_RS08720 HW43_08520 HW43_RS08720 1803191 1803820 + protein Sxy gene gene1742 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08720 HW43_RS08725 HW43_08525 HW43_RS08725 1803783 1805936 - membrane protein gene gene1743 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08725 HW43_RS08730 HW43_08530 HW43_RS08730 1805955 1806401 - hypothetical protein gene gene1744 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08730 HW43_RS08735 HW43_08535 helD helD 1806524 1808578 + DNA helicase IV catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand gene gene1745 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08735 HW43_RS08740 HW43_08540 mgsA mgsA 1808610 1809068 - methylglyoxal synthase catalyzes the formation of methylglyoxal from glycerone phosphate gene gene1746 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08740 HW43_RS08745 HW43_08545 HW43_RS08745 1809164 1809826 - hypothetical protein gene gene1747 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08745 HW43_RS08750 HW43_24890 HW43_RS08750 1809866 1810036 - hypothetical protein gene gene1748 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08750 HW43_RS08755 HW43_08550 HW43_RS08755 1809999 1810412 + hypothetical protein gene gene1749 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08755 HW43_RS08760 HW43_08555 HW43_RS08760 1810457 1810774 - heat-shock protein HspQ gene gene1750 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08760 HW43_RS08765 HW43_08560 HW43_RS08765 1810832 1812022 - ribosomal RNA large subunit methyltransferase I SAM-dependent%3Bcatalyzes the methylation of cytosine at position 1962 of the 23S rRNA gene gene1751 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08765 HW43_RS08770 HW43_08565 HW43_RS08770 1812117 1812395 + acylphosphatase catalyzes the hydrolysis of acylphosphate gene gene1752 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08770 HW43_RS08775 HW43_08570 HW43_RS08775 1812392 1812721 - sulfurtransferase TusE transfers sulfur from TusBCD complex to MnmA%3B involved in thiouridation of U34 position of some tRNAs gene gene1753 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08775 HW43_RS08780 HW43_08575 HW43_RS08780 1812812 1813471 - Modulator of FtsH protease inner membrane protein binds to the HflBKC complex which modulates FtsH activity gene gene1754 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08780 HW43_RS08785 HW43_08580 HW43_RS08785 1813678 1813765 - tRNA-Ser tRNA gene1755 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08785 HW43_RS08790 HW43_08585 HW43_RS08790 1814192 1815310 + hydrogenase gene gene1756 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08790 HW43_RS08795 HW43_08590 HW43_RS08795 1815307 1817100 + hydrogenase-1 large chain gene gene1757 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08795 HW43_RS08800 HW43_08595 HW43_RS08800 1817119 1817826 + Ni/Fe-hydrogenase B-type cytochrome subunit gene gene1758 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08800 HW43_RS08805 HW43_08600 HW43_RS08805 1817823 1818410 + HybD peptidase HyaD%3B endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1) gene gene1759 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08805 HW43_RS08810 HW43_08605 HW43_RS08810 1818407 1818805 + hydrogenase-1 operon protein HyaE involved in processing hydrogenase proteins HyaA and HyaB gene gene1760 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08810 HW43_RS08815 HW43_08610 HW43_RS08815 1818802 1819659 + hydrogenase-1 operon protein HyaF gene gene1761 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08815 HW43_RS08820 HW43_08615 HW43_RS08820 1819793 1821337 + cytochrome BD oxidase subunit I part of the aerobic respiratory chain%3B catalyzes the ubiquinol to ubiquinone gene gene1762 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08820 HW43_RS08825 HW43_08620 HW43_RS08825 1821349 1822485 + cytochrome bd-II ubiquinol oxidase subunit 2 gene gene1763 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08825 HW43_RS08830 HW43_24895 HW43_RS08830 1822498 1822590 + cytochrome bd-II oxidase subunit gene gene1764 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08830 HW43_RS08835 HW43_08625 HW43_RS08835 1822670 1823968 + phosphoanhydride phosphorylase gene gene1765 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08835 HW43_RS08840 HW43_08630 HW43_RS08840 1824083 1826263 - tyrosine-protein kinase etk gene gene1766 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08840 HW43_RS08845 HW43_08635 HW43_RS08845 1826283 1826729 - protein-tyrosine phosphatase Wzb shows phosphatase activity towards the autophosphorylated Wzc protein%2C which induces colanic acid biosynthesis%3B catalyzes the phosphorylation of UDP-glucose dehydrogenase%2C an enzyme involved in colanic acid biosynthesis gene gene1767 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08845 HW43_RS08850 HW43_08640 HW43_RS08850 1826717 1827856 - O-antigen capsule outer membrane auxillary protein export channel required for the translocation of capsular polysaccharide through the outer membrane gene gene1768 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08850 HW43_RS08855 HW43_08645 HW43_RS08855 1827902 1829998 - membrane protein gene gene1769 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08855 HW43_RS08860 HW43_08650 HW43_RS08860 1829998 1830744 - O-antigen capsule production periplasmic protein gene gene1770 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08860 HW43_RS08865 HW43_08655 HW43_RS08865 1830741 1831385 - hypothetical protein gene gene1771 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08865 HW43_RS08870 HW43_08660 HW43_RS08870 1831492 1831797 - threonine-rich inner membrane protein GfcA gene gene1772 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08870 HW43_RS08875 HW43_08665 HW43_RS08875 1832239 1832451 - cold-shock protein CspH gene gene1773 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08875 HW43_RS08880 HW43_08670 HW43_RS08880 1832737 1832949 + cold-shock protein CspG gene gene1774 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08880 HW43_RS08885 HW43_24900 HW43_RS08885 1833123 1833353 + cold-shock protein gene gene1775 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08885 HW43_RS08890 HW43_08675 HW43_RS08890 1833343 1833516 + protein GnsA gene gene1776 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08890 HW43_RS08895 HW43_08680 HW43_RS08895 1833565 1834638 - electron transporter YccM gene gene1777 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08895 HW43_RS08900 HW43_08685 HW43_RS08900 1834710 1837424 - histidine kinase Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide gene gene1778 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08900 HW43_RS08905 HW43_08690 HW43_RS08905 1837537 1838565 + TMAO reductase periplasmic sensory protein associated with the TorRS two-component regulatory system gene gene1779 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08905 HW43_RS08910 HW43_08695 HW43_RS08910 1838538 1839230 - two-component system response regulator gene gene1780 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08910 HW43_RS08915 HW43_08700 HW43_RS08915 1839360 1840532 + cytochrome c-type protein TorC with TorA forms the inducible trimethylamine N-oxide reductase which transfers electrons from menaquinones first to TorC then to TorA gene gene1781 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08915 HW43_RS08920 HW43_08705 HW43_RS08920 1840532 1843078 + trimethylamine N-oxide reductase I catalytic subunit catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine gene gene1782 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08920 HW43_RS08925 HW43_08710 torD torD 1843075 1843674 + chaperone protein TorD TorD%3B involved in the biogenesis of torA%3B acts on torA before the insertion of the molybdenum cofactor and%2C as a result%2C probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor gene gene1783 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08925 HW43_RS08930 HW43_08715 HW43_RS08930 1843767 1844072 - chaperone modulatory protein CbpM with CpbA modulates the activity of the dnaK chaperone system%3B interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA gene gene1784 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08930 HW43_RS08935 HW43_08720 HW43_RS08935 1844072 1844992 - DNA-binding protein functional analog of DnaJ%3B co-chaperone with DnaK%2C molecular chaperone in an adaptive response to environmental stresses other than heat shock gene gene1785 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08935 HW43_RS08940 HW43_08725 HW43_RS08940 1845252 1846508 + hypothetical protein gene gene1786 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08940 HW43_RS08945 HW43_08730 HW43_RS08945 1846801 1848042 + glucose-1-phosphatase/inositol phosphatase gene gene1787 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08945 HW43_RS08950 HW43_08735 HW43_RS08950 1848080 1848307 - hypothetical protein gene gene1788 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08950 HW43_RS08955 HW43_08740 HW43_RS08955 1848328 1848924 - NAD(P)H dehydrogenase (quinone) catalyzes the transfer of electrons from NADH to ubiquinone gene gene1789 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08955 HW43_RS08960 HW43_24905 HW43_RS08960 1849134 1849364 + hypothetical protein gene gene1790 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08960 HW43_RS08965 HW43_08745 HW43_RS08965 1849297 1849470 + KGG family protein gene gene1791 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08965 HW43_RS08970 HW43_08750 HW43_RS08970 1849553 1850881 - pyrimidine permease gene gene1792 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08970 HW43_RS08975 HW43_08755 HW43_RS08975 1850902 1851396 - FMN reductase gene gene1793 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08975 HW43_RS08980 HW43_08760 HW43_RS08980 1851407 1851997 - malonic semialdehyde reductase RutE gene gene1794 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08980 HW43_RS08985 HW43_08765 HW43_RS08985 1852007 1852807 - aminoacrylate hydrolase gene gene1795 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08985 HW43_RS08990 HW43_08770 HW43_RS08990 1852815 1853201 - aminoacrylate deaminase reactive intermediate detoxification%3B weak enamine/imine deaminase activity gene gene1796 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08990 HW43_RS08995 HW43_08775 HW43_RS08995 1853213 1853905 - peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB gene gene1797 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS08995 HW43_RS09000 HW43_08780 HW43_RS09000 1853905 1854996 - pyrimidine monooxygenase RutA gene gene1798 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09000 HW43_RS09005 HW43_08785 HW43_RS09005 1855284 1855922 + transcriptional regulator gene gene1799 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09005 HW43_RS09010 HW43_08790 putA putA 1855962 1859924 - bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase proline utilization protein A%3B multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate%3B in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus%3B forms dimers and is a peripherally membrane-associated protein gene gene1800 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09010 HW43_RS09015 HW43_08795 HW43_RS09015 1859979 1860188 + hypothetical protein gene gene1801 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09015 HW43_RS09020 HW43_08800 HW43_RS09020 1860347 1861855 + proline:sodium symporter involved in the sodium dependent uptake of proline gene gene1802 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09020 HW43_RS09025 HW43_24910 HW43_RS09025 1862041 1862361 - hypothetical protein gene gene1803 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09025 HW43_RS09030 HW43_08805 HW43_RS09030 1862397 1863227 + ferrous iron permease EfeU gene gene1804 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09030 HW43_RS09035 HW43_08810 HW43_RS09035 1863285 1864412 + iron ABC transporter substrate-binding protein with EfeUB forms an iron transport system which is silent in E. coli K-12 due to a mutation in EfeU gene gene1805 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09035 HW43_RS09040 HW43_08815 HW43_RS09040 1864418 1865689 + peroxidase gene gene1806 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09040 HW43_RS09045 HW43_24915 HW43_RS09045 1865756 1865953 - hypothetical protein gene gene1807 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09045 HW43_RS09050 HW43_08820 HW43_RS09050 1866308 1867096 + hypothetical protein gene gene1808 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09050 HW43_RS09055 HW43_08825 pgaD pgaD 1867146 1867559 - poly-beta-1%2C6-N-acetyl-D-glucosamine biosynthesis protein PgaD in Yersinia this gene is involved in biofilm formation and hemin adsorption%3B in Escherichia coli it is involved in PGA biosynthesis and export gene gene1809 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09055 HW43_RS09060 HW43_08830 HW43_RS09060 1867561 1868799 - N-glycosyltransferase predicted polysaccharide polymerase involved in biofilm formation%3B required for the synthesis of the beta-1%2C6-N-acetylglucosamine polysaccharide%3B PgaC%3B in Yersinia the HmsR protein is an inner membrane protein gene gene1810 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09060 HW43_RS09065 HW43_08835 pgaB pgaB 1868879 1870897 - poly-beta-1%2C6-N-acetyl-D-glucosamine N-deacetylase in Yersinia this protein is involved in biofilm formation and hemin adsorption%3B related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1%2C6-N-acetyl-D-glucosamine (PGA) export gene gene1811 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09065 HW43_RS09070 HW43_08840 pgaA pgaA 1870906 1873329 - poly-beta-1%2C6-N-acetyl-D-glucosamine export protein outer membrane protein essential for the synthesis of poly-beta-1%2C6-N-acetyl-D-glucosamine (PGA)%3B adhesin required for biofilm formation%3B PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface%3B member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia gene gene1812 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09070 HW43_RS09075 HW43_08845 HW43_RS09075 1873916 1875274 + diguanylate cyclase gene gene1813 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09075 HW43_RS09080 HW43_08850 HW43_RS09080 1875315 1876181 - transposase gene gene1814 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09080 HW43_RS09085 HW43_08855 HW43_RS09085 1876178 1876477 - transposase gene gene1815 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09085 HW43_RS09090 HW43_08860 HW43_RS09090 1876748 1877071 + hypothetical protein gene gene1816 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09090 HW43_RS09095 HW43_08865 HW43_RS09095 1877068 1878054 + hypothetical protein gene gene1817 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09095 HW43_RS09100 HW43_08870 HW43_RS09100 1878247 1878334 - tRNA-Ser tRNA gene1818 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09100 HW43_RS09105 HW43_08875 ghrA ghrA 1878568 1879506 + glyoxylate/hydroxypyruvate reductase A catalyzes the formation of glycolate and glycerate from glyoxylate and hydroxypyruvate%2C respectively gene gene1819 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09105 HW43_RS09110 HW43_08880 HW43_RS09110 1879561 1880298 + phosphatase gene gene1820 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09110 HW43_RS09115 HW43_08885 HW43_RS09115 1880322 1880876 + molecular chaperone gene gene1821 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09115 HW43_RS09120 HW43_08890 HW43_RS09120 1880978 1881469 + membrane protein gene gene1822 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09120 HW43_RS09125 HW43_08895 HW43_RS09125 1881533 1882366 - curli production assembly/transport component CsgG involved in the stability of the curlin proteins during assembly%3B involved in the secretion of the major curlin subunit CsgA across the outer membrane gene gene1823 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09125 HW43_RS09130 HW43_08900 HW43_RS09130 1882393 1882809 - curli production assembly/transport component CsgF nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation)%3B part of the curli secretion and assembly protein complex gene gene1824 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09130 HW43_RS09135 HW43_08905 HW43_RS09135 1882834 1883223 - curli production assembly/transport component CsgE chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation)%3B part of the curli secretion and assembly protein complex gene gene1825 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09135 HW43_RS09140 HW43_08910 HW43_RS09140 1883228 1883878 - transcriptional regulator activates the csgBA and csgDEFG operons involved in biofilm formation gene gene1826 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09140 HW43_RS09145 HW43_24920 HW43_RS09145 1884290 1884529 - hypothetical protein gene gene1827 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09145 HW43_RS09150 HW43_08915 csgB csgB 1884632 1885087 + curlin CsgB%3B functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface gene gene1828 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09150 HW43_RS09155 HW43_08920 csgA csgA 1885128 1885583 + major curlin subunit the major structural subunit of curlin which assemble to form curli which can bind to fibronectin gene gene1829 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09155 HW43_RS09160 HW43_08925 csgC csgC 1885642 1885974 + curli assembly protein CsgC involved in autoagglutination of curliated cells%3B not involved in production of curli fibers gene gene1830 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09160 HW43_RS09165 HW43_08930 HW43_RS09165 1886095 1886406 + hypothetical protein gene gene1831 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09165 HW43_RS09170 HW43_08935 HW43_RS09170 1886501 1887034 + RNase III inhibitor interacts and inactivates RNase III during cold shock gene gene1832 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09170 HW43_RS09175 HW43_08940 HW43_RS09175 1887036 1888457 + cardiolipin synthase C gene gene1833 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09175 HW43_RS09180 HW43_08945 opgC opgC 1888465 1889622 - glucan biosynthesis protein C required for the transfer of succinyl residues to osmoregulated periplasmic glucans gene gene1834 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09180 HW43_RS09185 HW43_24925 HW43_RS09185 1889667 1889810 - hypothetical protein gene gene1835 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09185 HW43_RS09190 HW43_24930 HW43_RS09190 1889814 1889945 - hypothetical protein gene gene1836 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09190 HW43_RS09195 HW43_08950 mdoG mdoG 1889998 1891551 + glucan biosynthesis protein G involved in the biosynthesis of osmoregulated periplasmic glucans%3B required for the assembly of the polyglucose structure of glucan gene gene1837 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09195 HW43_RS09200 HW43_08955 HW43_RS09200 1891574 1894087 + glucosyltransferase MdoH necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space gene gene1838 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09200 HW43_RS09205 HW43_08960 HW43_RS09205 1894260 1894487 + outer membrane integrity lipoprotein gene gene1839 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09205 HW43_RS09210 HW43_08965 HW43_RS09210 1894488 1894862 - acidic protein MsyB gene gene1840 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09210 HW43_RS09215 HW43_24935 HW43_RS09215 1894892 1894990 - hypothetical protein gene gene1841 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09215 HW43_RS09220 HW43_08970 HW43_RS09220 1894945 1896171 - multidrug resistance protein MdtG Confers resistance to fosfomycin and deoxycholate gene gene1842 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09220 HW43_RS09225 HW43_08975 HW43_RS09225 1896343 1897263 - lipid A biosynthesis lauroyltransferase Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA gene gene1843 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09225 HW43_RS09230 HW43_08980 HW43_RS09230 1897488 1898540 + sulfurtransferase gene gene1844 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09230 HW43_RS09235 HW43_08985 HW43_RS09235 1898582 1899157 - hypothetical protein gene gene1845 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09235 HW43_RS09240 HW43_08990 HW43_RS09240 1899161 1899727 - cytochrome B561 gene gene1846 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09240 HW43_RS09245 HW43_24940 HW43_RS09245 1899988 1900101 - hypothetical protein gene gene1847 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09245 HW43_RS09250 HW43_09005 solA solA 1900149 1901267 - N-methyl-L-tryptophan oxidase catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde%3B FAD-binding%3B can also catalyze the demethylation of other N-methyl amino acids gene gene1848 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09250 HW43_RS09255 HW43_09010 bssS bssS 1901382 1901636 - biofilm formation regulatory protein BssS BssS%3B regulator of biofilm through signal secretion%3B disruption of this gene in Escherichia coli led to effects on biofilm formation%2C alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing gene gene1849 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09255 HW43_RS09260 HW43_09015 HW43_RS09260 1901926 1902171 - DNA-damage-inducible protein I gene gene1850 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09260 HW43_RS09265 HW43_09020 HW43_RS09265 1902245 1903291 - dihydroorotase gene gene1851 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09265 HW43_RS09270 HW43_09025 HW43_RS09270 1903397 1903957 - lipoprotein gene gene1852 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09270 HW43_RS09275 HW43_09030 HW43_RS09275 1904091 1904738 - glutaredoxin cofactor involved in the reduction of disulfides gene gene1853 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09275 HW43_RS09280 HW43_09035 HW43_RS09280 1904802 1906010 - multidrug resistance protein MdtH Confers resistance to norfloxacin and enoxacin gene gene1854 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09280 HW43_RS09285 HW43_09040 HW43_RS09285 1906246 1906830 + ribosomal-protein-alanine acetyltransferase gene gene1855 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09285 HW43_RS09290 HW43_09045 HW43_RS09290 1906841 1907488 + hypothetical protein gene gene1856 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09290 HW43_RS09295 HW43_09050 HW43_RS09295 1907490 1908413 + oxidoreductase gene gene1857 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09295 HW43_RS09300 HW43_09055 HW43_RS09300 1908523 1910058 + virulence factor gene gene1858 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09300 HW43_RS09305 HW43_09060 HW43_RS09305 1910098 1910514 - flagella synthesis protein FlgN export chaperone for FlgK and FlgL gene gene1859 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09305 HW43_RS09310 HW43_09065 HW43_RS09310 1910519 1910812 - negative regulator of flagellin synthesis regulates the flagellar specific sigma28 transcription factor gene gene1860 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09310 HW43_RS09315 HW43_09070 flgA flgA 1910888 1911547 - flagellar basal body P-ring biosynthesis protein FlgA required for the assembly of the flagellar basal body P-ring gene gene1861 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09315 HW43_RS09320 HW43_09075 flgB flgB 1911702 1912118 + flagellar biosynthesis protein FlgB with FlgF and C makes up the proximal portion of the flagellar basal body rod%3B Vibrio parahaemolyticus protein is associated with the polar flagella gene gene1862 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09320 HW43_RS09325 HW43_09080 flgC flgC 1912122 1912526 + flagellar basal-body rod protein FlgC with FlgF and B makes up the proximal portion of the flagellar basal body rod gene gene1863 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09325 HW43_RS09330 HW43_09085 flgD flgD 1912538 1913233 + flagellar basal body rod modification protein FlgD acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod%3B Yersinia%2C Vibrio parahaemolyticus%2C Bradyrhizobium and other organisms have 2 copies of some flagellar genes%3B in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production gene gene1864 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09330 HW43_RS09335 HW43_09090 flgE flgE 1913258 1914463 + flagellar hook protein FlgE the hook connects flagellar basal body to the flagellar filament gene gene1865 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09335 HW43_RS09340 HW43_09095 flgF flgF 1914483 1915238 + flagellar basal body rod protein FlgF FlgF%2C with FlgB and C%2C makes up the proximal portion of the flagellar basal body rod gene gene1866 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09340 HW43_RS09345 HW43_09100 flgG flgG 1915376 1916158 + flagellar basal body rod protein FlgG makes up the distal portion of the flagellar basal body rod gene gene1867 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09345 HW43_RS09350 HW43_09105 flgH flgH 1916211 1916909 + flagellar L-ring protein part of the flagellar basal body which consists of four rings L%2CP%2C S and M mounted on a central rod gene gene1868 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09350 HW43_RS09355 HW43_09110 flgI flgI 1916921 1918018 + flagellar P-ring protein part of the basal body which consists of four rings L%2C P%2C S%2C and M mounted on a central rod%3B Vibrio parahaemolyticus%2C Yersinia%2C Bradyrhizobium and other bacteria have two copies of this and other flagellar genes%3B the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum gene gene1869 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09355 HW43_RS09360 HW43_09115 flgJ flgJ 1918018 1918959 + flagellar rod assembly protein FlgJ Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space gene gene1870 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09360 HW43_RS09365 HW43_09120 flgK flgK 1919025 1920668 + flagellar hook-associated protein 1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook gene gene1871 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09365 HW43_RS09370 HW43_09125 flgL flgL 1920680 1921633 + flagellar hook-associated protein FlgL with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook%3B Yersinia%2C Vibrio parahaemolyticus%2C Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes gene gene1872 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09370 HW43_RS09375 HW43_09130 rne rne 1921829 1925014 - ribonuclease E bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein%3B forms part of the membrane-associated degradosome complex along with PNPase%2C RhlB%2C and enolase gene gene1873 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09375 HW43_RS09380 HW43_24945 HW43_RS09380 1925149 1925469 + hypothetical protein gene gene1874 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09380 HW43_RS09385 HW43_09135 HW43_RS09385 1925587 1926546 + ribosomal large subunit pseudouridine synthase C catalyzes the transformation of uracil to pseudouracil at nucleotides U955%2C U2504%2C and U2580 in 23S rRNA gene gene1875 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09385 HW43_RS09390 HW43_09140 HW43_RS09390 1926658 1927242 - m(7)GTP pyrophosphatase Maf%3B overexpression in Bacillus subtilis inhibits septation in the dividing cell gene gene1876 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09390 HW43_RS09395 HW43_09145 HW43_RS09395 1927441 1927962 + DUF177 domain-containing protein gene gene1877 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09395 HW43_RS09400 HW43_09150 rpmF rpmF 1928014 1928187 + 50S ribosomal protein L32 some L32 proteins have zinc finger motifs consisting of CXXC while others do not gene gene1878 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09400 HW43_RS09405 HW43_09155 HW43_RS09405 1928298 1929338 + phosphate acyltransferase gene gene1879 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09405 HW43_RS09410 HW43_09160 HW43_RS09410 1929406 1930359 + 3-oxoacyl-ACP synthase FabH%3B beta-ketoacyl-acyl carrier protein synthase III%3B catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation%3B differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs gene gene1880 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09410 HW43_RS09415 HW43_09165 HW43_RS09415 1930375 1931304 + malonyl CoA-ACP transacylase gene gene1881 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09415 HW43_RS09420 HW43_09170 fabG fabG 1931317 1932051 + 3-oxoacyl-ACP reductase catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis gene gene1882 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09420 HW43_RS09425 HW43_09175 HW43_RS09425 1932262 1932498 + acyl carrier protein carries the fatty acid chain in fatty acid biosynthesis gene gene1883 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09425 HW43_RS09430 HW43_09180 HW43_RS09430 1932586 1933827 + 3-oxoacyl-ACP synthase II FabF%3B beta-ketoacyl-ACP synthase II%2C KASII%3B catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP%3B required for the elongation of short-chain unsaturated acyl-ACP gene gene1884 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09430 HW43_RS09435 HW43_09185 HW43_RS09435 1933947 1934756 + 4-amino-4-deoxychorismate lyase catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate gene gene1885 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09435 HW43_RS09440 HW43_09190 HW43_RS09440 1934759 1935781 + aminodeoxychorismate lyase gene gene1886 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09440 HW43_RS09445 HW43_09195 HW43_RS09445 1935771 1936412 + thymidylate kinase gene gene1887 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09445 HW43_RS09450 HW43_09200 HW43_RS09450 1936409 1937413 + DNA polymerase III subunit delta' catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand%3B the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA gene gene1888 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09450 HW43_RS09455 HW43_09205 HW43_RS09455 1937424 1938221 + DNAse gene gene1889 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09455 HW43_RS09460 HW43_09210 HW43_RS09460 1938516 1939949 + PTS glucose EIICB component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene1890 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09460 HW43_RS09465 HW43_09215 HW43_RS09465 1940009 1942198 - ferric-rhodotorulic acid outer membrane transporter gene gene1891 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09465 HW43_RS09470 HW43_09220 HW43_RS09470 1942532 1942891 + HIT-like protein HinT gene gene1892 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09470 HW43_RS09475 HW43_09225 HW43_RS09475 1942894 1943271 + membrane protein gene gene1893 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09475 HW43_RS09480 HW43_09230 HW43_RS09480 1943285 1943926 + penicillin-binding protein activator LpoB gene gene1894 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09480 HW43_RS09485 HW43_09235 thiK thiK 1943907 1944731 + thiamine kinase catalyzes the phosphorylation of thiamine to thiamine phosphate gene gene1895 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09485 HW43_RS09490 HW43_09240 HW43_RS09490 1944742 1945767 + beta-hexosaminidase hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides gene gene1896 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09490 HW43_RS09495 HW43_09245 HW43_RS09495 1945790 1946332 + hypothetical protein gene gene1897 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09495 HW43_RS09500 HW43_09250 HW43_RS09500 1946732 1948036 + NADH dehydrogenase gene gene1898 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09500 HW43_RS09505 HW43_09255 HW43_RS09505 1948263 1948802 + hypothetical protein gene gene1899 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09505 HW43_RS09510 HW43_09260 HW43_RS09510 1948864 1949496 - TetR family transcriptional regulator gene gene1900 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09510 HW43_RS09515 HW43_09265 HW43_RS09515 1949737 1949994 + multiple stress resistance protein BhsA gene gene1901 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09515 HW43_RS09520 HW43_09270 HW43_RS09520 1950076 1951035 - peptidoglycan-binding protein LysM gene gene1902 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09520 HW43_RS09525 HW43_09275 HW43_RS09525 1951182 1954628 - transcription-repair coupling factor gene gene1903 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09525 HW43_RS09530 HW43_09280 HW43_RS09530 1954756 1955829 - hypothetical protein gene gene1904 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09530 HW43_RS09535 HW43_09285 HW43_RS09535 1956091 1957290 + transporter part of the ATP-dependent transport system LolCDE%3B responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane gene gene1905 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09535 HW43_RS09540 HW43_09290 lolD lolD 1957283 1957984 + lipoprotein-releasing system ATP-binding protein LolD outer membrane specific%3B part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone gene gene1906 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09540 HW43_RS09545 HW43_09295 HW43_RS09545 1957984 1959228 + transporter part of the ATP-dependent transport system LolCDE%3B responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane gene gene1907 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09545 HW43_RS09550 HW43_09300 HW43_RS09550 1959257 1960168 + N-acetyl-D-glucosamine kinase catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine gene gene1908 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09550 HW43_RS09555 HW43_09305 HW43_RS09555 1960184 1961005 + NAD-dependent deacetylase Modulates the activities of several enzymes which are inactive in their acetylated form gene gene1909 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09555 HW43_RS09560 HW43_09310 HW43_RS09560 1961144 1961932 - membrane protein gene gene1910 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09560 HW43_RS09565 HW43_09315 HW43_RS09565 1961929 1962390 - hypothetical protein gene gene1911 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09565 HW43_RS09570 HW43_09320 potD potD 1962448 1963494 - spermidine/putrescine-binding periplasmic protein can transport spermidine and putrescine but affinity is higher for spermidine%3B forms a complex of PotA2BCD%3B PotD is a periplasmic component that binds the substrate gene gene1912 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09570 HW43_RS09575 HW43_09325 potC potC 1963491 1964285 - spermidine/putrescine ABC transporter permease can transport spermidine and putrescine but affinity is higher for spermidine%3B forms a complex of PotA2BCD%3B PotC is a membrane component gene gene1913 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09575 HW43_RS09580 HW43_09330 potB potB 1964282 1965139 - spermidine/putrescine ABC transporter permease can transport spermidine and putrescine but affinity is higher for spermidine%3B forms a complex of PotA2BCD%3B PotB is a membrane component gene gene1914 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09580 HW43_RS09585 HW43_09335 potA potA 1965123 1966259 - Fe3+/spermidine/putrescine ABC transporter ATP-binding protein functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport%3B PotA is the membrane-associated ATPase gene gene1915 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09585 HW43_RS09590 HW43_24950 HW43_RS09590 1966238 1966453 - hypothetical protein gene gene1916 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09590 HW43_RS09595 HW43_09340 HW43_RS09595 1966509 1967738 + peptidase T gene gene1917 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09595 HW43_RS09600 HW43_09345 HW43_RS09600 1967884 1969005 - 50S ribosomal protein L16 arginine hydroxylase gene gene1918 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09600 HW43_RS09605 HW43_09350 HW43_RS09605 1969254 1970483 + integrase gene gene1919 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09605 HW43_RS09610 HW43_24955 HW43_RS09610 1971099 1971851 + hypothetical protein gene gene1920 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09610 HW43_RS09615 HW43_09360 HW43_RS09615 1971951 1972178 - hypothetical protein gene gene1921 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09615 HW43_RS09620 HW43_09365 HW43_RS09620 1972236 1972415 - hypothetical protein gene gene1922 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09620 HW43_RS09625 HW43_09370 HW43_RS09625 1972608 1973171 + hypothetical protein gene gene1923 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09625 HW43_RS09630 HW43_24960 HW43_RS09630 1973158 1973358 + hypothetical protein gene gene1924 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09630 HW43_RS09635 HW43_09375 HW43_RS09635 1973364 1973663 + hypothetical protein gene gene1925 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09635 HW43_RS09640 HW43_09380 HW43_RS09640 1973660 1975057 + hypothetical protein gene gene1926 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09640 HW43_RS09645 HW43_09385 HW43_RS09645 1975260 1975511 + hypothetical protein gene gene1927 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09645 HW43_RS09650 HW43_09390 HW43_RS09650 1975508 1975822 + hypothetical protein gene gene1928 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09650 HW43_RS09655 HW43_09395 HW43_RS09655 1975832 1976242 + single-stranded DNA-binding protein gene gene1929 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09655 HW43_RS09660 HW43_09400 HW43_RS09660 1976253 1976501 + hypothetical protein gene gene1930 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09660 HW43_RS09665 HW43_09405 HW43_RS09665 1976643 1976867 + hypothetical protein gene gene1931 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09665 HW43_RS09670 HW43_09410 HW43_RS09670 1977160 1978317 + phage capsid protein gene gene1932 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09670 HW43_RS09675 HW43_09415 HW43_RS09675 1978372 1978929 + peptidase gene gene1933 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09675 HW43_RS09680 HW43_09420 HW43_RS09680 1978931 1980142 + head portal protein gene gene1934 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09680 HW43_RS09685 HW43_09425 HW43_RS09685 1980139 1980477 + head-tail adaptor protein gene gene1935 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09685 HW43_RS09690 HW43_09430 HW43_RS09690 1980474 1980770 + hypothetical protein gene gene1936 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09690 HW43_RS09695 HW43_09435 HW43_RS09695 1980770 1981210 + HNH endonuclease gene gene1937 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09695 HW43_RS09700 HW43_24965 HW43_RS09700 1981203 1981376 + hypothetical protein gene gene1938 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09700 HW43_RS09705 HW43_09440 HW43_RS09705 1981501 1981857 + hypothetical protein gene gene1939 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09705 HW43_RS09710 HW43_09445 HW43_RS09710 1981841 1983502 + terminase gene gene1940 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09710 HW43_RS09715 HW43_09450 HW43_RS09715 1983516 1983797 + hypothetical protein gene gene1941 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09715 HW43_RS09720 HW43_09460 HW43_RS09720 1984463 1985923 - sensor protein PhoQ gene gene1942 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09720 HW43_RS09725 HW43_09465 HW43_RS09725 1985923 1986594 - two-component system response regulator response regulator in two-component regulatory system with PhoQ%3B involved in magnesium starvation and stress gene gene1943 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09725 HW43_RS09730 HW43_09470 HW43_RS09730 1986762 1988132 - adenylosuccinate lyase Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide gene gene1944 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09730 HW43_RS09735 HW43_09475 HW43_RS09735 1988136 1988777 - lysogenization regulator HflD%3B UPF0274%3B in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein%3B in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis gene gene1945 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09735 HW43_RS09740 HW43_09480 mnmA mnmA 1988813 1989919 - tRNA-specific 2-thiouridylase MnmA catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs gene gene1946 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09740 HW43_RS09745 HW43_09485 HW43_RS09745 1989973 1990434 - phosphatase gene gene1947 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09745 HW43_RS09750 HW43_09490 HW43_RS09750 1990444 1991097 - ribosomal large subunit pseudouridine synthase E catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA gene gene1948 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09750 HW43_RS09755 HW43_09495 HW43_RS09755 1991269 1992519 + isocitrate dehydrogenase Converts isocitrate to alpha ketoglutarate gene gene1949 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09755 HW43_RS09760 HW43_24970 HW43_RS09760 1992622 1992945 - anti-adapter protein IraM interacts RssB preventing the degradation of the stress sigma factor RpoS gene gene1950 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09760 HW43_RS09765 HW43_24975 HW43_RS09765 1993478 1993588 - hypothetical protein gene gene1951 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09765 HW43_RS09770 HW43_09500 HW43_RS09770 1993641 1994045 - DUF1398 domain-containing protein gene gene1952 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09770 HW43_RS09775 HW43_09505 HW43_RS09775 1994266 1994997 - transcriptional regulator gene gene1953 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09775 HW43_RS09780 HW43_09510 HW43_RS09780 1995202 1996413 - diguanylate phosphodiesterase gene gene1954 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09780 HW43_RS09785 HW43_09515 HW43_RS09785 1996727 1996963 + two-component-system connector protein YcgZ gene gene1955 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09785 HW43_RS09790 HW43_09520 HW43_RS09790 1997006 1997278 + two-component-system connector protein YmgA gene gene1956 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09790 HW43_RS09795 HW43_09525 HW43_RS09795 1997307 1997573 + RcsB connector protein for regulation of biofilm and acid-resistance gene gene1957 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09795 HW43_RS09800 HW43_09530 HW43_RS09800 1997686 1997934 + hypothetical protein gene gene1958 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09800 HW43_RS09805 HW43_09535 HW43_RS09805 1998265 1999788 + hypothetical protein gene gene1959 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09805 HW43_RS09810 HW43_09540 HW43_RS09810 1999920 2000138 + hypothetical protein gene gene1960 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09810 HW43_RS09815 HW43_24980 HW43_RS09815 2000143 2000271 - hypothetical protein gene gene1961 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09815 HW43_RS09820 HW43_09545 HW43_RS09820 2000538 2000747 + ATPase gene gene1962 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09820 HW43_RS09825 HW43_09550 HW43_RS09825 2000864 2003185 + autotransporter gene gene1963 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09825 HW43_RS09830 HW43_09555 HW43_RS09830 2003242 2003571 - hypothetical protein gene gene1964 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09830 HW43_RS09835 HW43_09560 HW43_RS09835 2003581 2003925 - hypothetical protein gene gene1965 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09835 HW43_RS09840 HW43_24985 HW43_RS09840 2003927 2004100 - hypothetical protein gene gene1966 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09840 HW43_RS09845 HW43_09565 HW43_RS09845 2004519 2004845 + ATPase gene gene1967 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09845 HW43_RS09850 HW43_09570 minE minE 2005217 2005483 - cell division topological specificity factor works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell gene gene1968 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09850 HW43_RS09855 HW43_09575 HW43_RS09855 2005487 2006299 - septum site-determining protein MinD ATPase%3B with MinC inhibits cell division by blocking formation of the polar Z ring septums gene gene1969 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09855 HW43_RS09860 HW43_09580 minC minC 2006323 2007018 - septum site-determining protein MinC blocks the formation of polar Z-ring septums gene gene1970 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09860 HW43_RS09865 HW43_09585 HW43_RS09865 2007538 2007906 + hypothetical protein gene gene1971 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09865 HW43_RS09870 HW43_09590 HW43_RS09870 2008026 2008427 - hypothetical protein gene gene1972 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09870 HW43_RS09875 HW43_09595 HW43_RS09875 2008636 2008962 + hypothetical protein gene gene1973 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09875 HW43_RS09880 HW43_09600 HW43_RS09880 2009034 2009693 + hypothetical protein gene gene1974 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09880 HW43_RS09885 HW43_09605 HW43_RS09885 2009770 2010231 + hypothetical protein gene gene1975 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09885 HW43_RS09890 HW43_09610 HW43_RS09890 2010438 2010719 - hemolysin E gene gene1976 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09890 HW43_RS09895 HW43_09615 HW43_RS09895 2010839 2011348 - hemolysin activation protein gene gene1977 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09895 HW43_RS09900 HW43_09620 HW43_RS09900 2011721 2012140 + protein UmuD binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC)%3B involved in translesion polymerization gene gene1978 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09900 HW43_RS09905 HW43_09625 HW43_RS09905 2012140 2013408 + protein UmuC binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC)%3B involved in translesion polymerization gene gene1979 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09905 HW43_RS09910 HW43_09630 HW43_RS09910 2013454 2013984 - disulfide bond formation protein B disulfide oxidoreductase%3B integral membrane protein%3B required for perioplasmic disulfide bond formation%3B oxidizes DsbA protein gene gene1980 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09910 HW43_RS09915 HW43_09635 nhaB nhaB 2014130 2015671 - Na+/H+ antiporter NhaB involved in regulation of intracellular pH under alkaline conditions gene gene1981 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09915 HW43_RS09920 HW43_09640 HW43_RS09920 2015893 2016612 + fatty acid metabolism regulator protein Multifunctional regulator of fatty acid metabolism gene gene1982 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09920 HW43_RS09925 HW43_09645 HW43_RS09925 2016664 2018196 - SpoVR family stationary phase gene gene1983 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09925 HW43_RS09930 HW43_09650 HW43_RS09930 2018526 2019824 + D-amino acid dehydrogenase catalyzes the oxidative deamination of D-amino acids gene gene1984 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09930 HW43_RS09935 HW43_09655 HW43_RS09935 2019834 2020904 + alanine racemase converts L-alanine to D-alanine which is used in cell wall biosynthesis%3B binds one pyridoxal phosphate per monomer%3B forms a homodimer gene gene1985 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09935 HW43_RS09940 HW43_09660 cvrA cvrA 2021290 2023026 - K+/H+ antiporter NhaP2 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter%3B can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli gene gene1986 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09940 HW43_RS09945 HW43_09665 ldcA ldcA 2023121 2024035 - L%2CD-carboxypeptidase A catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine gene gene1987 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09945 HW43_RS09950 HW43_09670 emtA emtA 2024135 2024746 + murein transglycosylase catalyzes the cleavage of 1-4 beta-glycoside linkaged between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan gene gene1988 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09950 HW43_RS09955 HW43_09675 HW43_RS09955 2024748 2025482 - flagellar brake protein YcgR gene gene1989 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09955 HW43_RS09960 HW43_09680 HW43_RS09960 2025683 2025937 + hypothetical protein gene gene1990 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09960 HW43_RS09965 HW43_09685 HW43_RS09965 2026115 2026555 + hypothetical protein gene gene1991 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09965 HW43_RS09970 HW43_09690 treA treA 2026634 2028331 - periplasmic trehalase periplasmic%3B catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell gene gene1992 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09970 HW43_RS09975 HW43_09695 HW43_RS09975 2028651 2030069 - dihydroxyacetone kinase subunit DhaM phosphotransferaese subunit%3B phosphorylates dihydroxyacetone along with DhaK/DhaL gene gene1993 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09975 HW43_RS09980 HW43_09700 HW43_RS09980 2030080 2030712 - dihydroxyacetone kinase subunit DhaL with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone gene gene1994 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09980 HW43_RS09985 HW43_09705 HW43_RS09985 2030723 2031793 - dihydroxyacetone kinase subunit DhaK with DhaL and DhaM forms dihydroxyacetone kinase%2C which is responsible for phosphorylating dihydroxyacetone%3B DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase gene gene1995 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09985 HW43_RS09990 HW43_09710 HW43_RS09990 2032021 2033940 + Fis family transcriptional regulator Positively regulates the dhaKLM operon from a sigma-70 promoter gene gene1996 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09990 HW43_RS09995 HW43_09715 HW43_RS09995 2034040 2036907 - hypothetical protein gene gene1997 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS09995 HW43_RS10000 HW43_09720 HW43_RS10000 2037252 2037455 + membrane protein gene gene1998 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10000 HW43_RS10005 HW43_09725 ychF ychF 2037748 2038839 - ribosome-binding ATPase YchF EngD%3B translation-associated GTPase%3B the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3)%3B fluorescence spectroscopy revealed nucleic acid binding%3B the yeast protein YBR025c interacts with the translation elongation factor eEF1 gene gene1999 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10005 HW43_RS10010 HW43_09730 HW43_RS10010 2038956 2039540 - peptidyl-tRNA hydrolase gene gene2000 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10010 HW43_RS10015 HW43_09735 HW43_RS10015 2039818 2040096 + membrane protein YchH%3B transcription activated by CRP (cyclic AMP receptor protein)%2C a global transcription factor involved in regulation of metabolism in enteric bacteria%3B ychH presents a class II promoter to bind CRP%3B unknown function gene gene2001 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10015 HW43_RS10020 HW43_09740 HW43_RS10020 2040151 2041803 - transporter role in sulfate transport across the inner membrane%3B member of the SulP family of sulfate transporters%3B seems to mediate transport via sulfate/proton symport gene gene2002 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10020 HW43_RS10025 HW43_09745 HW43_RS10025 2041955 2042902 - ribose-phosphate pyrophosphokinase catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP gene gene2003 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10025 HW43_RS10030 HW43_09750 HW43_RS10030 2043053 2043904 - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase gene gene2004 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10030 HW43_RS10035 HW43_09755 lolB lolB 2043904 2044527 - outer membrane lipoprotein LolB Incorporates lipoproteins in the outer membrane after they are released by the LolA protein gene gene2005 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10035 HW43_RS10040 HW43_09760 hemA hemA 2044741 2045997 + glutamyl-tRNA reductase catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH%3B the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid%3B functions in porphyrin (tetrapyrroles) biosynthesis%3B the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins gene gene2006 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10040 HW43_RS10045 HW43_09765 prfA prfA 2046039 2047121 + peptide chain release factor 1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1%3B this protein is similar to release factor 2 gene gene2007 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10045 HW43_RS10050 HW43_09770 HW43_RS10050 2047121 2047954 + N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase HemK%3B PrmC%3B transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB gene gene2008 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10050 HW43_RS10055 HW43_09775 HW43_RS10055 2047951 2048343 + protein sirB2 gene gene2009 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10055 HW43_RS10060 HW43_09780 HW43_RS10060 2048347 2049156 + protein sirB1 gene gene2010 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10060 HW43_RS10065 HW43_09785 HW43_RS10065 2049192 2050046 + 2-dehydro-3-deoxyphosphooctonate aldolase catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis gene gene2011 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10065 HW43_RS10070 HW43_24990 HW43_RS10070 2050195 2050329 - hypothetical protein gene gene2012 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10070 HW43_RS10075 HW43_24995 HW43_RS10075 2050730 2050864 - hypothetical protein gene gene2013 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10075 HW43_RS10080 HW43_25000 HW43_RS10080 2051266 2051400 - hypothetical protein gene gene2014 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10080 HW43_RS10085 HW43_09805 HW43_RS10085 2051778 2052878 - sodium:proton antiporter gene gene2015 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10085 HW43_RS10090 HW43_09810 chaB chaB 2053148 2053378 + cation transport regulator in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA%3B has weak affinity for calcium and magnesium ions gene gene2016 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10090 HW43_RS10095 HW43_09815 HW43_RS10095 2053536 2054231 + transporter gene gene2017 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10095 HW43_RS10100 HW43_09820 HW43_RS10100 2054275 2054628 - hypothetical protein gene gene2018 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10100 HW43_RS10105 HW43_09825 HW43_RS10105 2054813 2056207 + invasin gene gene2019 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10105 HW43_RS10110 HW43_09830 HW43_RS10110 2056208 2056858 - transcriptional regulator two-component response regulator NarL%3B phosphorylated by NarQ%3B activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase gene gene2020 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10110 HW43_RS10115 HW43_09835 HW43_RS10115 2056851 2058647 - nitrate/nitrite two-component system sensor histidine kinase gene gene2021 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10115 HW43_RS10120 HW43_25005 HW43_RS10120 2058673 2058891 + hypothetical protein gene gene2022 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10120 HW43_RS10125 HW43_09840 HW43_RS10125 2058986 2060377 + nitrate/nitrite transporter NarK involved in the transport of nitrate and nitrite gene gene2023 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10125 HW43_RS10130 HW43_09845 narZ narZ 2060893 2064636 + nitrate reductase A subunit alpha with NarYV catalyzes the reduction of nitrate%3B the beta subunit is an iron sulfur cluster containing electron transfer subunit%3B one of 3 nitrate reductases in E. coli%3B expression of nitrate reductase Z is not dependent on nitrate levels gene gene2024 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10130 HW43_RS10135 HW43_09850 narH narH 2064633 2066171 + nitrate reductase subunit beta with NarGJI catalyzes the reduction of nitrate%3B the beta subunit is an iron sulfur cluster containing electron transfer subunit%3B one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high gene gene2025 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10135 HW43_RS10140 HW43_09855 HW43_RS10140 2066168 2066878 + nitrate reductase molybdenum cofactor assembly chaperone NarJ delta subunit of nitrate reductase 1%3B chaperone for the insertion of the molybdenum cofactor and assembly of nitrate reductase 1 gene gene2026 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10140 HW43_RS10145 HW43_09860 narI narI 2066878 2067555 + respiratory nitrate reductase subunit gamma with NarGJH catalyzes the reduction of nitrate%3B the gamma subunit localizes NarGHI to the membrane%3B one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high gene gene2027 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10145 HW43_RS10150 HW43_09865 HW43_RS10150 2067917 2068001 - tRNA-Tyr tRNA gene2028 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10150 HW43_RS10155 HW43_09870 HW43_RS10155 2068036 2068120 - tRNA-Tyr tRNA gene2029 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10155 HW43_RS10160 HW43_09875 HW43_RS10160 2068280 2069122 - formyltetrahydrofolate deformylase gene gene2030 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10160 HW43_RS10165 HW43_09880 HW43_RS10165 2069172 2069630 - hypothetical protein gene gene2031 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10165 HW43_RS10170 HW43_09885 HW43_RS10170 2069743 2070648 + NTE family protein RssA gene gene2032 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10170 HW43_RS10175 HW43_09890 HW43_RS10175 2070740 2071753 + regulator of RpoS gene gene2033 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10175 HW43_RS10180 HW43_09895 HW43_RS10180 2071955 2072863 + UTP--glucose-1-phosphate uridylyltransferase together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase%2C an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate%3B regulates cellular levels of UDP-glucose gene gene2034 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10180 HW43_RS10185 HW43_09900 HW43_RS10185 2073007 2073420 - DNA-binding protein H-NS gene gene2035 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10185 HW43_RS10190 HW43_09905 HW43_RS10190 2074025 2074642 + thymidine kinase catalyzes the formation of thymidine 5'-phosphate from thymidine gene gene2036 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10190 HW43_RS10195 HW43_09910 HW43_RS10195 2074944 2077619 - aldehyde-alcohol dehydrogenase gene gene2037 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10195 HW43_RS10200 HW43_09915 HW43_RS10200 2078096 2078743 + hypothetical protein gene gene2038 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10200 HW43_RS10205 HW43_09920 HW43_RS10205 2079481 2081112 + peptide ABC transporter substrate-binding protein is involved in the transport of the murein peptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate gene gene2039 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10205 HW43_RS10210 HW43_09925 oppB oppB 2081198 2082118 + peptide ABC transporter permease gene gene2040 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10210 HW43_RS10215 HW43_09930 HW43_RS10215 2082133 2083041 + peptide ABC transporter permease with OppABDF is involved in the transport of oligopeptides of up to 5 amino acids into the cell gene gene2041 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10215 HW43_RS10220 HW43_09935 oppD oppD 2083053 2084066 + peptide ABC transporter ATP-binding protein gene gene2042 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10220 HW43_RS10225 HW43_09940 HW43_RS10225 2084063 2085067 + oligopeptide transport ATP-binding protein OppF with OppABCD is involved in the transport of oligopeptides%3B OppF and OppD are ATP-binding proteins gene gene2043 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10225 HW43_RS10230 HW43_09945 HW43_RS10230 2085120 2085449 - hypothetical protein highly acidic protein%3B the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi)%3B binds heat-unstable protein (HU-alpha) which is a histone-like protein gene gene2044 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10230 HW43_RS10235 HW43_09950 cls cls 2085484 2086944 - cardiolipin synthase catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) gene gene2045 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10235 HW43_RS10240 HW43_25010 HW43_RS10240 2086976 2087260 + hypothetical protein gene gene2046 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10240 HW43_RS10245 HW43_09955 HW43_RS10245 2087315 2088568 - voltage-gated potassium channel gene gene2047 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10245 HW43_RS10250 HW43_09960 HW43_RS10250 2088867 2089163 - hypothetical protein unknown function%3B YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase%2C but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity gene gene2048 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10250 HW43_RS10255 HW43_09965 HW43_RS10255 2089387 2090106 + protein TonB membrane spanning protein in TonB-ExbB-ExbD complex%3B transduces proton motive force of the cytoplasmic membrane to outer membrane transporters%3B involved in the transport of ron-siderophore complexes%2C vitamin B12 and colicins gene gene2049 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10255 HW43_RS10260 HW43_09970 HW43_RS10260 2090146 2090544 - acyl-CoA thioester hydrolase YciA gene gene2050 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10260 HW43_RS10265 HW43_09975 HW43_RS10265 2090649 2091188 - intracellular septation protein A Involved in cell division%3B probably involved in intracellular septation gene gene2051 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10265 HW43_RS10270 HW43_09980 HW43_RS10270 2091218 2091961 - hypothetical protein gene gene2052 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10270 HW43_RS10275 HW43_09985 HW43_RS10275 2092318 2092956 + outer membrane protein W receptor for colicin S4 gene gene2053 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10275 HW43_RS10280 HW43_09990 HW43_RS10280 2093002 2094132 - integrase gene gene2054 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10280 HW43_RS10285 HW43_09995 HW43_RS10285 2094110 2094358 - excisionase gene gene2055 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10285 HW43_RS10290 HW43_10000 HW43_RS10290 2094423 2096894 - hypothetical protein gene gene2056 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10290 HW43_RS10295 HW43_10005 HW43_RS10295 2096990 2097178 - hypothetical protein gene gene2057 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10295 HW43_RS10300 HW43_10010 HW43_RS10300 2097175 2097363 - cell division inhibitor gene gene2058 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10300 HW43_RS10305 HW43_25015 HW43_RS10305 2097380 2097736 + hypothetical protein gene gene2059 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10305 HW43_RS10310 HW43_25020 HW43_RS10310 2097660 2097868 + hypothetical protein gene gene2060 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10310 HW43_RS10315 HW43_10020 HW43_RS10315 2098148 2098516 - hypothetical protein gene gene2061 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10315 HW43_RS10320 HW43_25025 HW43_RS10320 2098528 2098680 - hypothetical protein gene gene2062 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10320 HW43_RS10325 HW43_10030 HW43_RS10325 2098845 2099252 - transcriptional regulator The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC%2C but its specific role in cellular replication and mode of action are still unknown. gene gene2063 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10325 HW43_RS10330 HW43_10035 HW43_RS10330 2099336 2099566 + transcriptional regulator gene gene2064 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10330 HW43_RS10335 HW43_10040 HW43_RS10335 2099550 2100071 + hypothetical protein gene gene2065 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10335 HW43_RS10340 HW43_10045 HW43_RS10340 2100052 2101017 + phage O protein family gene gene2066 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10340 HW43_RS10345 HW43_10050 HW43_RS10345 2101024 2101764 + DNA replication protein DnaC gene gene2067 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10345 HW43_RS10350 HW43_10055 HW43_RS10350 2101794 2102555 + hypothetical protein gene gene2068 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10350 HW43_RS10355 HW43_10060 HW43_RS10355 2102615 2102809 + hypothetical protein gene gene2069 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10355 HW43_RS10360 HW43_10065 HW43_RS10360 2103151 2103702 + antirepressor gene gene2070 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10360 HW43_RS10365 HW43_25030 HW43_RS10365 2103699 2103872 - hypothetical protein gene gene2071 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10365 HW43_RS10370 HW43_10070 HW43_RS10370 2103917 2104129 + Regulatory protein mokC gene gene2072 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10370 HW43_RS10375 HW43_10075 HW43_RS10375 2104232 2104549 - DNA-binding protein gene gene2073 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10375 HW43_RS10380 HW43_25035 HW43_RS10380 2104649 2104914 - hypothetical protein gene gene2074 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10380 HW43_RS10385 HW43_10090 HW43_RS10385 2105171 2105365 + hypothetical protein gene gene2075 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10385 HW43_RS10390 HW43_10095 HW43_RS10390 2105419 2105688 + hypothetical protein gene gene2076 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10390 HW43_RS10395 HW43_10100 HW43_RS10395 2105690 2106739 + hypothetical protein gene gene2077 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10395 HW43_RS10400 HW43_10105 HW43_RS10400 2106752 2107114 + endodeoxyribonuclease gene gene2078 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10400 HW43_RS10405 HW43_10110 HW43_RS10405 2107107 2107772 + antiterminator gene gene2079 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10405 HW43_RS10410 HW43_10115 HW43_RS10410 2108026 2108739 + membrane protein gene gene2080 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10410 HW43_RS10415 HW43_10120 HW43_RS10415 2108913 2109110 + hypothetical protein gene gene2081 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10415 HW43_RS10420 HW43_10125 HW43_RS10420 2109280 2110320 + DNA adenine methylase gene gene2082 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10420 HW43_RS10425 HW43_10130 HW43_RS10425 2110361 2110436 + tRNA-Met tRNA gene2083 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10425 HW43_RS10430 HW43_10135 HW43_RS10430 2110445 2110521 + tRNA-Arg tRNA gene2084 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10430 HW43_RS10435 HW43_10140 HW43_RS10435 2110800 2111228 + hypothetical protein gene gene2085 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10435 HW43_RS10440 HW43_25040 HW43_RS10440 2111924 2112649 + transcriptional regulator gene gene2086 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10440 HW43_RS10445 HW43_10155 HW43_RS10445 2112738 2113016 + hypothetical protein gene gene2087 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10445 HW43_RS10450 HW43_10165 HW43_RS10450 2114512 2116476 + 5'-nucleotidase gene gene2088 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10450 HW43_RS10455 HW43_10170 HW43_RS10455 2116611 2116790 + hypothetical protein gene gene2089 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10455 HW43_RS10460 HW43_10175 HW43_RS10460 2116831 2117103 + hypothetical protein gene gene2090 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10460 HW43_RS10465 HW43_10180 HW43_RS10465 2117180 2117395 + holin gene gene2091 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10465 HW43_RS10470 HW43_10185 HW43_RS10470 2117399 2118190 + hypothetical protein gene gene2092 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10470 HW43_RS10475 HW43_10190 HW43_RS10475 2118702 2119235 + lysozyme gene gene2093 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10475 HW43_RS10485 HW43_10200 HW43_RS10485 2119589 2119720 + membrane protein gene gene2094 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10485 HW43_RS10490 HW43_10205 HW43_RS10490 2119723 2120190 + endopeptidase gene gene2095 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10490 HW43_RS10495 HW43_10210 HW43_RS10495 2120214 2120438 + hypothetical protein gene gene2096 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10495 HW43_RS10500 HW43_25045 HW43_RS10500 2120399 2120674 + hypothetical protein gene gene2097 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10500 HW43_RS10505 HW43_10215 HW43_RS10505 2120783 2121109 + membrane protein gene gene2098 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10505 HW43_RS10510 HW43_10220 HW43_RS10510 2121241 2121441 - hypothetical protein gene gene2099 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10510 HW43_RS10515 HW43_10225 HW43_RS10515 2121483 2121848 + HNH nuclease gene gene2100 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10515 HW43_RS10520 HW43_25050 HW43_RS10520 2121817 2121954 + hypothetical protein gene gene2101 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10520 HW43_RS10525 HW43_10230 HW43_RS10525 2122137 2122700 + terminase gene gene2102 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10525 HW43_RS10530 HW43_10235 HW43_RS10530 2122697 2124358 + terminase gene gene2103 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10530 HW43_RS10535 HW43_10240 HW43_RS10535 2124422 2126359 + hypothetical protein gene gene2104 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10535 HW43_RS10540 HW43_10245 HW43_RS10540 2126404 2126625 + hypothetical protein gene gene2105 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10540 HW43_RS10545 HW43_10250 HW43_RS10545 2126571 2127935 + hypothetical protein gene gene2106 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10545 HW43_RS10550 HW43_10255 HW43_RS10550 2127932 2129155 + phage portal protein gene gene2107 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10550 HW43_RS10555 HW43_10260 HW43_RS10555 2129152 2129478 + DNA-packaging protein gene gene2108 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10555 HW43_RS10560 HW43_10265 HW43_RS10560 2129488 2129838 + head-tail adaptor protein gene gene2109 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10560 HW43_RS10565 HW43_10270 HW43_RS10565 2129835 2130281 + hypothetical protein gene gene2110 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10565 HW43_RS10570 HW43_10275 HW43_RS10570 2130278 2130622 + hypothetical protein gene gene2111 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10570 HW43_RS10575 HW43_10280 HW43_RS10575 2130689 2131405 + tail protein gene gene2112 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10575 HW43_RS10580 HW43_10285 HW43_RS10580 2131420 2131794 + tail assembly protein gene gene2113 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10580 HW43_RS10585 HW43_10290 HW43_RS10585 2131818 2132099 + phage tail protein gene gene2114 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10585 HW43_RS10590 HW43_10295 HW43_RS10590 2132147 2135389 + hypothetical protein gene gene2115 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10590 HW43_RS10595 HW43_10300 HW43_RS10595 2135382 2135723 + tail protein gene gene2116 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10595 HW43_RS10600 HW43_10305 HW43_RS10600 2135723 2136421 + tail protein gene gene2117 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10600 HW43_RS10605 HW43_10310 HW43_RS10605 2136432 2137175 + tail protein gene gene2118 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10605 HW43_RS10610 HW43_10315 HW43_RS10610 2137172 2137717 + tail protein gene gene2119 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10610 HW43_RS10615 HW43_10320 HW43_RS10615 2138628 2142323 + tail fiber protein gene gene2120 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10615 HW43_RS10620 HW43_10325 HW43_RS10620 2142392 2143015 + membrane protein gene gene2121 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10620 HW43_RS10625 HW43_10330 HW43_RS10625 2143165 2144433 + phage tail protein gene gene2122 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10625 HW43_RS10630 HW43_10335 HW43_RS10630 2144502 2145173 + hypothetical protein gene gene2123 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10630 HW43_RS10635 HW43_25055 HW43_RS10635 2145581 2146138 - antirepressor gene gene2124 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10635 HW43_RS10640 HW43_10345 HW43_RS10640 2146781 2147287 - hypothetical protein gene gene2125 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10640 HW43_RS10645 HW43_10350 HW43_RS10645 2147333 2147833 - hypothetical protein gene gene2126 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10645 HW43_RS10650 HW43_10355 HW43_RS10650 2147919 2148098 - hypothetical protein gene gene2127 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10650 HW43_RS10655 HW43_10360 HW43_RS10655 2148479 2149285 - tryptophan synthase subunit alpha gene gene2128 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10655 HW43_RS10660 HW43_10365 HW43_RS10660 2149285 2150478 - tryptophan synthase subunit beta catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate gene gene2129 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10660 HW43_RS10665 HW43_10370 HW43_RS10665 2150490 2151848 - phosphoribosylanthranilate isomerase monomeric bifunctional protein%3B functions in tryptophan biosynthesis pathway%3B phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate gene gene2130 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10665 HW43_RS10670 HW43_10375 HW43_RS10670 2151852 2153447 - bifunctional protein TrpGD bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase%3B TrpD%3B forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine%3B also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate%3B functions in tryptophan biosynthesis gene gene2131 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10670 HW43_RS10675 HW43_10380 HW43_RS10675 2153447 2155009 - anthranilate synthase subunit I gene gene2132 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10675 HW43_RS10680 HW43_10385 HW43_RS10680 2155283 2156164 + PHP domain-containing protein YciV gene gene2133 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10680 HW43_RS10685 HW43_10390 HW43_RS10685 2156161 2156781 + RNA binding protein gene gene2134 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10685 HW43_RS10690 HW43_10395 HW43_RS10690 2156882 2157754 + ribosomal large subunit pseudouridine synthase B catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA gene gene2135 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10690 HW43_RS10695 HW43_10400 HW43_RS10695 2157794 2158384 - cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase catalyzes the formation of adenosylcobalamide from cobinamide and the formation of coenzyme B12 from cob(I)alamin gene gene2136 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10695 HW43_RS10700 HW43_10405 HW43_RS10700 2158381 2159139 - oxoacyl-ACP reductase gene gene2137 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10700 HW43_RS10705 HW43_25060 HW43_RS10705 2159183 2159347 - hypothetical protein gene gene2138 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10705 HW43_RS10710 HW43_10410 HW43_RS10710 2159359 2160408 + protease multicopy suppressor of htrA(degP) gene gene2139 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10710 HW43_RS10715 HW43_10415 HW43_RS10715 2160444 2160695 - hypothetical protein gene gene2140 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10715 HW43_RS10720 HW43_25065 HW43_RS10720 2160800 2160952 + hypothetical protein gene gene2141 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10720 HW43_RS10725 HW43_10420 HW43_RS10725 2161075 2163672 + DNA topoisomerase 1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining%2C maintains net negative superhelicity gene gene2142 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10725 HW43_RS10730 HW43_10425 cysB cysB 2163882 2164856 + transcriptional regulator LysR-type transcriptional regulator%3B contains helix-turn-helix (HTH) motif%3B in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon%3B autoregulates expression%3B crystal structure of Klebsiella aerogenes showed tetramer formation gene gene2143 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10730 HW43_RS10735 HW43_25070 HW43_RS10735 2165187 2165315 + hypothetical protein gene gene2144 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10735 HW43_RS10740 HW43_25075 HW43_RS10740 2165318 2165485 + hypothetical protein gene gene2145 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10740 HW43_RS10745 HW43_25080 HW43_RS10745 2165559 2165684 - hypothetical protein gene gene2146 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10745 HW43_RS10750 HW43_10445 HW43_RS10750 2165858 2168533 + aconitate hydratase Catalyzes the conversion of citrate to isocitrate gene gene2147 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10750 HW43_RS10755 HW43_10450 ribA ribA 2168597 2169187 - GTP cyclohydrolase-2 catalyzes the conversion of GTP to formate and 2%2C5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate gene gene2148 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10755 HW43_RS10760 HW43_10455 HW43_RS10760 2169357 2170121 + phosphatidylglycerophosphatase B gene gene2149 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10760 HW43_RS10765 HW43_10460 HW43_RS10765 2170270 2170578 + LPS assembly protein A gene gene2150 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10765 HW43_RS10770 HW43_10465 HW43_RS10770 2170585 2171754 + LPS assembly protein B gene gene2151 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10770 HW43_RS10775 HW43_10475 HW43_RS10775 2171947 2172684 + orotidine 5'-phosphate decarboxylase gene gene2152 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10775 HW43_RS10780 HW43_10480 HW43_RS10780 2172684 2173010 + initiation factor function involved in start site selection during the initiation of translation gene gene2153 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10780 HW43_RS10785 HW43_10485 HW43_RS10785 2173136 2173354 - osmotically-inducible lipoprotein B gene gene2154 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10785 HW43_RS10790 HW43_10490 HW43_RS10790 2173623 2174372 - DeoR family transcriptional regulator gene gene2155 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10790 HW43_RS10795 HW43_25085 HW43_RS10795 2174462 2174635 - hypothetical protein gene gene2156 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10795 HW43_RS10800 HW43_10500 HW43_RS10800 2174782 2176767 - cyclic di-GMP phosphodiesterase Gmr c-di-GMP phosphodiesterase%3B probably degrades signalling molecule c-di-GMP gene gene2157 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10800 HW43_RS10805 HW43_25090 HW43_RS10805 2176821 2176925 + hypothetical protein gene gene2158 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10805 HW43_RS10810 HW43_10510 HW43_RS10810 2177003 2178937 - exoribonuclease 2 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction gene gene2159 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10810 HW43_RS10815 HW43_10515 HW43_RS10815 2179005 2180132 - hypothetical protein gene gene2160 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10815 HW43_RS10820 HW43_10520 HW43_RS10820 2180277 2181065 - enoyl-ACP reductase [NADH] Catalyzes a key regulatory step in fatty acid biosynthesis gene gene2161 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10820 HW43_RS10825 HW43_25095 HW43_RS10825 2181234 2181345 - hypothetical protein gene gene2162 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10825 HW43_RS10830 HW43_25100 HW43_RS10830 2181433 2181781 - hypothetical protein gene gene2163 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10830 HW43_RS10835 HW43_10530 HW43_RS10835 2181852 2182658 - peptide transport system ATP-binding protein SapF gene gene2164 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10835 HW43_RS10840 HW43_10535 HW43_RS10840 2182660 2183652 - peptide transport system ATP-binding protein SapD involved in resistance to antimibial peptides gene gene2165 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10840 HW43_RS10845 HW43_10540 HW43_RS10845 2183652 2184542 - peptide ABC transporter permease gene gene2166 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10845 HW43_RS10850 HW43_10545 HW43_RS10850 2184529 2185494 - peptide ABC transporter permease gene gene2167 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10850 HW43_RS10855 HW43_10550 HW43_RS10855 2185491 2187134 - peptide ABC transporter permease gene gene2168 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10855 HW43_RS10860 HW43_25105 HW43_RS10860 2187177 2187377 - hypothetical protein gene gene2169 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10860 HW43_RS10865 HW43_10555 HW43_RS10865 2187447 2187692 - hypothetical protein gene gene2170 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10865 HW43_RS10870 HW43_10560 HW43_RS10870 2187826 2189196 - putrescine importer PuuP gene gene2171 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10870 HW43_RS10875 HW43_10565 HW43_RS10875 2189499 2190917 - gamma-glutamylputrescine synthetase PuuA gene gene2172 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10875 HW43_RS10880 HW43_10570 puuD puuD 2191129 2191893 + gamma-glutamyl-gamma-aminobutyrate hydrolase catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate gene gene2173 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10880 HW43_RS10885 HW43_10575 HW43_RS10885 2191920 2192477 + transcriptional regulator regulates genes involved in putrescine degradation gene gene2174 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10885 HW43_RS10890 HW43_10580 HW43_RS10890 2192752 2194239 + aldehyde dehydrogenase PuuC gene gene2175 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10890 HW43_RS10895 HW43_10585 HW43_RS10895 2194241 2195521 + gamma-glutamylputrescine oxidoreductase catalyzes the formation of gamma-glutamyl-gamma-aminobutyraldehyde from gamma-glutamylputrescine gene gene2176 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10895 HW43_RS10900 HW43_10590 HW43_RS10900 2195559 2196824 + 4-aminobutyrate aminotransferase PuuE catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate gene gene2177 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10900 HW43_RS10905 HW43_10595 pspF pspF 2196944 2197921 - transcriptional regulator transcriptional activator for pspABCE which are induced in response to phage proteins%2C membrane altering stresses%2C and impaired proton expor gene gene2178 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10905 HW43_RS10910 HW43_10600 HW43_RS10910 2198088 2198756 + phage shock protein A involved in maintaining membrane potential under membrane stress conditions%3B also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF gene gene2179 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10910 HW43_RS10915 HW43_10605 pspB pspB 2198810 2199034 + phage-shock protein DNA-binding transcriptional regulator%3B acts together with PspC to induce psp operon during infection with phage%2C exposure to ethanol or osmotic shock%3B forms a complex with PspA and C%3B PspC is required for PspAB binding gene gene2180 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10915 HW43_RS10920 HW43_10610 HW43_RS10920 2199034 2199393 + phage shock protein C with PsbB forms toxin/antitoxin pair%3B activates the psp operon in response to phage infection%2C exposure to ethanol or osmotic shock gene gene2181 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10920 HW43_RS10925 HW43_10615 HW43_RS10925 2199402 2199623 + phage shock protein D gene gene2182 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10925 HW43_RS10930 HW43_10620 HW43_RS10930 2199698 2200012 + thiosulfate sulfurtransferase PspE rhodanese%3B catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide gene gene2183 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10930 HW43_RS10935 HW43_10625 HW43_RS10935 2200225 2201904 + sucrose phosphorylase gene gene2184 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10935 HW43_RS10940 HW43_10630 HW43_RS10940 2201918 2203210 + sugar ABC transporter substrate-binding protein gene gene2185 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10940 HW43_RS10945 HW43_10635 HW43_RS10945 2203231 2204112 + ABC transporter permease gene gene2186 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10945 HW43_RS10950 HW43_10640 HW43_RS10950 2204099 2204941 + ABC transporter permease gene gene2187 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10950 HW43_RS10955 HW43_25110 HW43_RS10955 2204972 2206024 + alcohol dehydrogenase gene gene2188 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10955 HW43_RS10960 HW43_10650 HW43_RS10960 2206042 2206830 + hypothetical protein gene gene2189 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10960 HW43_RS10965 HW43_10655 HW43_RS10965 2206852 2207895 + oxidoreductase gene gene2190 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10965 HW43_RS10970 HW43_10660 HW43_RS10970 2207892 2210159 + hydrolase gene gene2191 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10970 HW43_RS10975 HW43_10665 HW43_RS10975 2210156 2210815 + beta-phosphoglucomutase catalyzes the interconversion of beta-D-glucose 6-phosphate to beta-D-glucose 1-phosphate gene gene2192 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10975 HW43_RS10980 HW43_10670 HW43_RS10980 2210829 2211911 + sugar ABC transporter ATP-binding protein gene gene2193 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10980 HW43_RS10985 HW43_10675 HW43_RS10985 2211956 2212861 + membrane protein gene gene2194 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10985 HW43_RS10990 HW43_10680 HW43_RS10990 2212972 2213970 - LacI family transcriptional regulator gene gene2195 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10990 HW43_RS10995 HW43_10685 HW43_RS10995 2214125 2215522 + hypothetical protein gene gene2196 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS10995 HW43_RS11000 HW43_10690 HW43_RS11000 2215519 2216580 + membrane protein gene gene2197 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11000 HW43_RS11005 HW43_10695 HW43_RS11005 2216728 2218269 + transcriptional regulator regulates genes involved in the biosynthesis and transport of aromatic amino acids gene gene2198 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11005 HW43_RS11010 HW43_10700 tpx tpx 2218313 2218819 - thiol peroxidase antioxidant activity%3B thioredoxin-dependent thiol peroxidase%3B forms homodimers in solution%3B shows substrate specificity to alkyl hydroperoxides%3B periplasmic protein gene gene2199 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11010 HW43_RS11015 HW43_10705 HW43_RS11015 2218938 2219903 + L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-alanyl-D-glutamate to L-alanyl-L-glutamate gene gene2200 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11015 HW43_RS11020 HW43_10710 HW43_RS11020 2219878 2220606 - murein peptide amidase A gene gene2201 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11020 HW43_RS11025 HW43_10715 HW43_RS11025 2220915 2221553 - NAD-dependent dehydratase gene gene2202 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11025 HW43_RS11030 HW43_10720 HW43_RS11030 2221571 2222503 - alpha/beta hydrolase gene gene2203 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11030 HW43_RS11035 HW43_10725 HW43_RS11035 2222503 2223423 - hypothetical protein gene gene2204 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11035 HW43_RS11040 HW43_10730 HW43_RS11040 2223561 2224460 + transcriptional regulator gene gene2205 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11040 HW43_RS11045 HW43_25115 HW43_RS11045 2224549 2224674 + hypothetical protein gene gene2206 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11045 HW43_RS11050 HW43_10735 HW43_RS11050 2224797 2226410 + peptide ABC transporter substrate-binding protein is involved in the transport of the murein peptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate gene gene2207 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11050 HW43_RS11055 HW43_10740 HW43_RS11055 2226461 2227492 - low conductance mechanosensitive channel YnaI gene gene2208 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11055 HW43_RS11060 HW43_10745 HW43_RS11060 2227736 2227993 + DUF2534 domain-containing protein gene gene2209 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11060 HW43_RS11065 HW43_10750 HW43_RS11065 2228043 2228993 - universal stress protein E with UspC and UspD is involved in resistance to UV irradiation gene gene2210 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11065 HW43_RS11070 HW43_10755 HW43_RS11070 2229145 2229897 - fumarate and nitrate reduction regulatory protein Global transcription factor that controls the expression of over 100 target genes in response to anoxia gene gene2211 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11070 HW43_RS11075 HW43_10760 HW43_RS11075 2230092 2230607 - O-6-alkylguanine-DNA--cysteine-protein methyltransferase gene gene2212 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11075 HW43_RS11080 HW43_10765 HW43_RS11080 2230618 2232144 - transporter gene gene2213 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11080 HW43_RS11085 HW43_25120 HW43_RS11085 2232074 2232268 - hypothetical protein gene gene2214 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11085 HW43_RS11090 HW43_10770 HW43_RS11090 2232181 2233626 - peptidase M20 gene gene2215 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11090 HW43_RS11095 HW43_10775 HW43_RS11095 2233626 2234936 - peptidase M20 gene gene2216 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11095 HW43_RS11100 HW43_10785 HW43_RS11100 2235112 2236020 + LysR family transcriptional regulator gene gene2217 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11100 HW43_RS11105 HW43_10790 HW43_RS11105 2236350 2236913 + DNA endonuclease SmrA gene gene2218 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11105 HW43_RS11110 HW43_10795 HW43_RS11110 2236934 2238166 - diguanylate cyclase gene gene2219 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11110 HW43_RS11115 HW43_10800 zntB zntB 2238421 2239404 + zinc transporter ZntB gene gene2220 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11115 HW43_RS11120 HW43_25125 HW43_RS11120 2239679 2239852 + hypothetical protein gene gene2221 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11120 HW43_RS11125 HW43_10805 HW43_RS11125 2239882 2241255 + RNA helicase exhibits an RNA-dependent ATPase activity%2C specifically stimulated by bacterial 23S rRNA gene gene2222 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11125 HW43_RS11130 HW43_10810 HW43_RS11130 2241384 2242319 - tRNA 2-thiocytidine biosynthesis protein TtcA TtcA%3B YdaO%3B catalyzes the thiolation of cytosine 32 in specific tRNAs%3B forms 2-thiocytidine (s(2)C) gene gene2223 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11130 HW43_RS11135 HW43_10815 HW43_RS11135 2242495 2242929 - universal stress protein F gene gene2224 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11135 HW43_RS11140 HW43_10820 HW43_RS11140 2243070 2244203 - outer membrane protein N allows for ions and hydrophilic solutes to cross the outer membrane gene gene2225 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11140 HW43_RS11145 HW43_10825 HW43_RS11145 2244571 2248095 - pyruvate-flavodoxin oxidoreductase gene gene2226 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11145 HW43_RS11150 HW43_10830 HW43_RS11150 2248369 2248635 + DUF333 domain-containing protein gene gene2227 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11150 HW43_RS11155 HW43_10835 HW43_RS11155 2248632 2249054 - heat-shock protein hslJ gene gene2228 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11155 HW43_RS11160 HW43_10840 HW43_RS11160 2249165 2250154 - lactate dehydrogenase fermentative%3B catalyzes the formationof pyruvate from lactate gene gene2229 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11160 HW43_RS11165 HW43_10845 HW43_RS11165 2250362 2253001 + hypothetical protein gene gene2230 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11165 HW43_RS11170 HW43_10850 HW43_RS11170 2252998 2253183 + hypothetical protein gene gene2231 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11170 HW43_RS11175 HW43_10855 HW43_RS11175 2253191 2253517 + hypothetical protein gene gene2232 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11175 HW43_RS11180 HW43_10860 HW43_RS11180 2253689 2254594 - transcriptional activator FeaR activator of genes involved in phenylacetic acid catabolism gene gene2233 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11180 HW43_RS11185 HW43_10865 HW43_RS11185 2254830 2256329 + aldehyde dehydrogenase gene gene2234 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11185 HW43_RS11190 HW43_10870 tynA tynA 2256387 2258660 - tyramine oxidase catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine gene gene2235 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11190 HW43_RS11195 HW43_10875 HW43_RS11195 2258908 2260953 - enoyl-CoA hydratase catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA gene gene2236 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11195 HW43_RS11200 HW43_10880 paaA paaA 2261238 2262167 + 1%2C2-phenylacetyl-CoA epoxidase subunit A with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA gene gene2237 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11200 HW43_RS11205 HW43_10885 paaB paaB 2262179 2262466 + 1%2C2-phenylacetyl-CoA epoxidase subunit B with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA%3B involved in phenylacetate degradation gene gene2238 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11205 HW43_RS11210 HW43_10890 HW43_RS11210 2262475 2263221 + phenylacetic acid degradation protein gene gene2239 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11210 HW43_RS11215 HW43_10895 HW43_RS11215 2263236 2263733 + phenylacetic acid degradation protein gene gene2240 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11215 HW43_RS11220 HW43_10900 HW43_RS11220 2263741 2264811 + phenylacetate-CoA oxygenase subunit PaaK gene gene2241 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11220 HW43_RS11225 HW43_10905 HW43_RS11225 2264808 2265575 + 2%2C3-dehydroadipyl-CoA hydratase gene gene2242 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11225 HW43_RS11230 HW43_10910 HW43_RS11230 2265575 2266363 + enoyl-CoA hydratase Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA gene gene2243 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11230 HW43_RS11235 HW43_10915 HW43_RS11235 2266365 2267792 + 3-hydroxyadipyl-CoA dehydrogenase gene gene2244 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11235 HW43_RS11240 HW43_10920 HW43_RS11240 2267782 2268204 + acyl-CoA thioesterase gene gene2245 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11240 HW43_RS11245 HW43_10925 HW43_RS11245 2268204 2269409 + beta-ketoadipyl-CoA thiolase catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA gene gene2246 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11245 HW43_RS11250 HW43_10930 HW43_RS11250 2269436 2270749 + phenylacetate-CoA ligase gene gene2247 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11250 HW43_RS11255 HW43_10935 HW43_RS11255 2270850 2271800 + phenylacetic acid degradation protein gene gene2248 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11255 HW43_RS11260 HW43_10940 HW43_RS11260 2271782 2272372 + phenylacetic acid degradation protein PaaY involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities gene gene2249 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11260 HW43_RS11265 HW43_10945 HW43_RS11265 2272603 2273463 + oxidoreductase gene gene2250 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11265 HW43_RS11270 HW43_10950 HW43_RS11270 2273527 2275833 + hypothetical protein gene gene2251 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11270 HW43_RS11275 HW43_10955 HW43_RS11275 2276004 2276609 + membrane protein gene gene2252 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11275 HW43_RS11280 HW43_10960 HW43_RS11280 2276609 2277505 + hypothetical protein gene gene2253 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11280 HW43_RS11285 HW43_25130 HW43_RS11285 2277521 2279277 + hypothetical protein gene gene2254 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11285 HW43_RS11290 HW43_10970 HW43_RS11290 2279267 2280583 + hypothetical protein gene gene2255 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11290 HW43_RS11295 HW43_10975 HW43_RS11295 2280634 2281239 - FMN-dependent NADH-azoreductase FMN-dependent%3B requires NADH%3B catalyzes the cleavage of azo bond in aromatic azo compounds gene gene2256 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11295 HW43_RS11300 HW43_10980 HW43_RS11300 2281440 2285342 + ATP-dependent RNA helicase HrpA involved in the post-transcriptional processing of the daa operon mRNA%2C which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain gene gene2257 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11300 HW43_RS11305 HW43_10985 HW43_RS11305 2285614 2286414 + hypothetical protein gene gene2258 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11305 HW43_RS11310 HW43_10990 HW43_RS11310 2286611 2288050 + aldehyde dehydrogenase NAD-linked gene gene2259 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11310 HW43_RS11315 HW43_10995 HW43_RS11315 2288092 2289093 - glyceraldehyde-3-phosphate dehydrogenase NAD-dependent%3B catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate%3B active during glycolysis gene gene2260 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11315 HW43_RS11320 HW43_11000 HW43_RS11320 2289282 2289812 + cytochrome B561 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm gene gene2261 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11320 HW43_RS11325 HW43_25135 HW43_RS11325 2290057 2290230 + periplasmic protein gene gene2262 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11325 HW43_RS11330 HW43_11010 HW43_RS11330 2290302 2290451 - protein HokB gene gene2263 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11330 HW43_RS11335 HW43_11015 HW43_RS11335 2290850 2292490 + methyl-accepting chemotaxis protein gene gene2264 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11335 HW43_RS11340 HW43_11020 HW43_RS11340 2292528 2293451 - transcriptional regulator gene gene2265 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11340 HW43_RS11345 HW43_11025 HW43_RS11345 2293668 2295011 + hypothetical protein gene gene2266 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11345 HW43_RS11350 HW43_11030 mdoD mdoD 2295272 2296891 + glucan biosynthesis protein D involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans gene gene2267 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11350 HW43_RS11355 HW43_25140 HW43_RS11355 2296812 2297015 - hypothetical protein gene gene2268 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11355 HW43_RS11360 HW43_11035 HW43_RS11360 2297031 2297255 + hypothetical protein gene gene2269 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11360 HW43_RS11365 HW43_11040 HW43_RS11365 2297318 2297854 + ribosomal-protein-L7/L12-serine acetyltransferase gene gene2270 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11365 HW43_RS11370 HW43_11045 HW43_RS11370 2297849 2298829 - acetyltransferase gene gene2271 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11370 HW43_RS11375 HW43_11050 HW43_RS11375 2298941 2299945 + potassium-tellurite ethidium and proflavin transporter gene gene2272 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11375 HW43_RS11380 HW43_11055 HW43_RS11380 2299942 2300535 + tellurite methyltransferase with TehA confers resistance to tellurite gene gene2273 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11380 HW43_RS11385 HW43_11060 HW43_RS11385 2300838 2301506 + hypothetical protein gene gene2274 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11385 HW43_RS11390 HW43_11065 HW43_RS11390 2301811 2301963 - transposase gene gene2275 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11390 HW43_RS11395 HW43_11070 HW43_RS11395 2302097 2303245 + transposase gene gene2276 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11395 HW43_RS11400 HW43_11075 HW43_RS11400 2303285 2304460 - membrane protein gene gene2277 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11400 HW43_RS11405 HW43_11080 HW43_RS11405 2304552 2305088 + transcriptional regulator gene gene2278 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11405 HW43_RS11410 HW43_11085 HW43_RS11410 2305161 2307122 + protease gene gene2279 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11410 HW43_RS11415 HW43_25145 HW43_RS11415 2307214 2307384 - hypothetical protein gene gene2280 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11415 HW43_RS11420 HW43_25150 HW43_RS11420 2307666 2307842 + mRNA interferase HicA gene gene2281 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11420 HW43_RS11425 HW43_11095 HW43_RS11425 2307867 2308304 + antitoxin gene gene2282 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11425 HW43_RS11430 HW43_11100 HW43_RS11430 2308383 2309789 + GntR family transcriptional regulator gene gene2283 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11430 HW43_RS11435 HW43_11105 HW43_RS11435 2310034 2311179 + spermidine/putrescine ABC transporter substrate-binding protein gene gene2284 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11435 HW43_RS11440 HW43_11110 HW43_RS11440 2311197 2312210 + ABC transporter ATPase gene gene2285 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11440 HW43_RS11445 HW43_11115 HW43_RS11445 2312211 2313152 + spermidine/putrescine ABC transporter permease gene gene2286 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11445 HW43_RS11450 HW43_11120 HW43_RS11450 2313142 2313936 + ABC transporter permease gene gene2287 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11450 HW43_RS11455 HW43_11125 HW43_RS11455 2313958 2315382 + gamma-aminobutyraldehyde dehydrogenase catalyzes the formation of 4-aminobutanoate from 4-aminobutanal%3B involved in putrescine degradation gene gene2288 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11455 HW43_RS11460 HW43_11130 HW43_RS11460 2315592 2316401 + acetyltransferase gene gene2289 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11460 HW43_RS11465 HW43_25155 HW43_RS11465 2316743 2316934 + hypothetical protein gene gene2290 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11465 HW43_RS11470 HW43_25160 HW43_RS11470 2317093 2317266 + DUF2566 domain-containing protein gene gene2291 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11470 HW43_RS11475 HW43_11140 HW43_RS11475 2317352 2317585 + hypothetical protein gene gene2292 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11475 HW43_RS11480 HW43_11145 HW43_RS11480 2317586 2318035 - hypothetical protein gene gene2293 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11480 HW43_RS11485 HW43_11150 HW43_RS11485 2318032 2318550 - N-acetyltransferase gene gene2294 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11485 HW43_RS11490 HW43_11160 HW43_RS11490 2318731 2319768 + oxidoreductase gene gene2295 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11490 HW43_RS11495 HW43_11165 HW43_RS11495 2319966 2320631 + transcriptional regulator gene gene2296 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11495 HW43_RS11500 HW43_11170 HW43_RS11500 2320667 2322769 - TonB-dependent receptor gene gene2297 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11500 HW43_RS11505 HW43_11175 HW43_RS11505 2323011 2324072 + hypothetical protein gene gene2298 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11505 HW43_RS11510 HW43_11180 HW43_RS11510 2324187 2325686 - L-asparagine permease involved in the transporte of L-asparagine gene gene2299 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11510 HW43_RS11515 HW43_11185 HW43_RS11515 2325953 2326570 + hypothetical protein gene gene2300 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11515 HW43_RS11520 HW43_11190 HW43_RS11520 2326646 2326858 + hypothetical protein gene gene2301 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11520 HW43_RS11525 HW43_11195 HW43_RS11525 2327679 2329787 + type IV secretion protein Rhs gene gene2302 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11525 HW43_RS11530 HW43_11200 HW43_RS11530 2329854 2334062 + RHS element protein RhsA gene gene2303 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11530 HW43_RS11535 HW43_11210 HW43_RS11535 2334260 2334469 + hypothetical protein gene gene2304 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11535 HW43_RS11540 HW43_25165 HW43_RS11540 2334977 2335615 + transposase gene gene2305 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11540 HW43_RS11545 HW43_11220 HW43_RS11545 2335584 2335886 + transposase gene gene2306 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11545 HW43_RS11550 HW43_11225 HW43_RS11550 2335916 2336368 + hypothetical protein gene gene2307 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11550 HW43_RS11555 HW43_11230 HW43_RS11555 2336634 2336828 + dihydroneopterin aldolase gene gene2308 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11555 HW43_RS11560 HW43_11235 HW43_RS11560 2336909 2341168 + type IV secretion protein Rhs gene gene2309 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11560 HW43_RS11565 HW43_11240 HW43_RS11565 2341180 2341629 + hypothetical protein gene gene2310 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11565 HW43_RS11570 HW43_11245 HW43_RS11570 2341983 2342681 + hypothetical protein gene gene2311 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11570 HW43_RS11575 HW43_11250 HW43_RS11575 2342714 2342941 + tautomerase PptA 4-OT%3B member of subfamily 5%3B forms a dimer%3B the function in the Escherichia coli cell is unknown gene gene2312 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11575 HW43_RS11580 HW43_11255 HW43_RS11580 2342945 2343514 - hypothetical protein gene gene2313 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11580 HW43_RS11585 HW43_11260 HW43_RS11585 2343687 2344532 + N-hydroxyarylamine O-acetyltransferase catalyzes the addition of the acetyl moity of acetyl-CoA to an N-hydroxy-arylamine to form an N-acetoxyarylamine gene gene2314 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11585 HW43_RS11590 HW43_11265 HW43_RS11590 2344628 2345521 - hypothetical protein gene gene2315 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11590 HW43_RS11595 HW43_11270 narI narI 2345601 2346281 - respiratory nitrate reductase subunit gamma with NarGJH catalyzes the reduction of nitrate%3B the gamma subunit localizes NarGHI to the membrane%3B one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high gene gene2316 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11595 HW43_RS11600 HW43_11275 HW43_RS11600 2346278 2346973 - nitrate reductase molybdenum cofactor assembly chaperone NarJ delta subunit of nitrate reductase 1%3B chaperone for the insertion of the molybdenum cofactor and assembly of nitrate reductase 1 gene gene2317 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11600 HW43_RS11605 HW43_11280 narH narH 2346973 2348517 - nitrate reductase A subunit beta with NarGJI catalyzes the reduction of nitrate%3B the beta subunit is an iron sulfur cluster containing electron transfer subunit%3B one of 3 nitrate reductases in E. coli and in E. coli is expressed when nitrate levels are high gene gene2318 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11605 HW43_RS11610 HW43_11285 narZ narZ 2348514 2352254 - nitrate reductase A subunit alpha with NarYV catalyzes the reduction of nitrate%3B the beta subunit is an iron sulfur cluster containing electron transfer subunit%3B one of 3 nitrate reductases in E. coli%3B expression of nitrate reductase Z is not dependent on nitrate levels gene gene2319 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11610 HW43_RS11615 HW43_11290 HW43_RS11615 2352336 2353724 - nitrite extrusion protein 2 involved in the transport of nitrate and nitrite gene gene2320 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11615 HW43_RS11620 HW43_11295 HW43_RS11620 2354048 2355379 - hypothetical protein gene gene2321 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11620 HW43_RS11625 HW43_11300 HW43_RS11625 2355403 2355693 - lipoprotein gene gene2322 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11625 HW43_RS11630 HW43_11305 HW43_RS11630 2355952 2356776 - aromatic amino acid exporter gene gene2323 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11630 HW43_RS11635 HW43_11310 HW43_RS11635 2357065 2357652 + sulfate ABC transporter substrate-binding protein gene gene2324 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11635 HW43_RS11640 HW43_11315 HW43_RS11640 2357701 2360112 + formate dehydrogenase subunit alpha gene gene2325 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11640 HW43_RS11645 HW43_11320 HW43_RS11645 2360125 2361009 + formate dehydrogenase nitrate-inducible iron-sulfur subunit beta subunit%3B involved in the use of formate as an electron donor during aerobic respiration%3B acts to transfer electrons from the major(alpha subunit) to the cytochrome b556(gamma subunit) gene gene2326 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11645 HW43_RS11650 HW43_11325 HW43_RS11650 2361002 2361655 + formate dehydrogenase nitrate-inducible cytochrome b556(Fdn) subunit cytochrome b556(FDO) component%3B heme containing gene gene2327 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11650 HW43_RS11655 HW43_11330 HW43_RS11655 2361706 2361990 - transcriptional regulator gene gene2328 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11655 HW43_RS11660 HW43_11335 adhP adhP 2362137 2363147 - acetaldehyde reductase similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs gene gene2329 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11660 HW43_RS11665 HW43_11340 HW43_RS11665 2363281 2364978 - NAD-dependent malic enzyme gene gene2330 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11665 HW43_RS11670 HW43_11345 rpsV rpsV 2365135 2365272 - stationary-phase-induced ribosome-associated protein protein D%3B stationary-phase-induced ribosome-associated%3B in Escherichia coli this protein becomes associated with the ribosome%3B expression increases during stationary phase gene gene2331 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11670 HW43_RS11675 HW43_11350 HW43_RS11675 2365374 2365589 - protein bdm gene gene2332 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11675 HW43_RS11680 HW43_11355 HW43_RS11680 2365934 2366365 + peroxiredoxin OsmC gene gene2333 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11680 HW43_RS11685 HW43_11360 HW43_RS11685 2366421 2367347 - peptide ABC transporter ATP-binding protein gene gene2334 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11685 HW43_RS11690 HW43_11365 HW43_RS11690 2367340 2368326 - peptide ABC transporter substrate-binding protein gene gene2335 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11690 HW43_RS11695 HW43_11370 HW43_RS11695 2368323 2369219 - cytochrome C550 gene gene2336 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11695 HW43_RS11700 HW43_11375 HW43_RS11700 2369216 2370238 - peptide ABC transporter permease gene gene2337 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11700 HW43_RS11705 HW43_11380 HW43_RS11705 2370240 2371790 - peptide ABC transporter substrate-binding protein gene gene2338 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11705 HW43_RS11710 HW43_11385 HW43_RS11710 2371804 2372385 - D-alanyl-D-alanine dipeptidase catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent%3B involved in peptidoglycan synthesis gene gene2339 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11710 HW43_RS11715 HW43_11390 HW43_RS11715 2372643 2375066 - diguanylate phosphodiesterase heme-regulated phosphodiesterase with phosphodiesterase activity with cGMP%3B cold- and stationary phase-induced bioflim regulator%3B oxygen sensor gene gene2340 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11715 HW43_RS11720 HW43_11395 HW43_RS11720 2375067 2376449 - diguanylate cyclase gene gene2341 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11720 HW43_RS11725 HW43_11400 HW43_RS11725 2376826 2377980 - hypothetical protein gene gene2342 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11725 HW43_RS11730 HW43_11405 HW43_RS11730 2378276 2379811 - glutamate/gamma-aminobutyrate antiporter gene gene2343 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11730 HW43_RS11735 HW43_11410 HW43_RS11735 2379967 2381367 - glutamate decarboxylase beta gene gene2344 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11735 HW43_RS11740 HW43_25170 HW43_RS11740 2381378 2381476 - hypothetical protein gene gene2345 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11740 HW43_RS11745 HW43_11415 HW43_RS11745 2381729 2384512 - zinc protease gene gene2346 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11745 HW43_RS11750 HW43_11420 HW43_RS11750 2384569 2386941 - hypothetical protein gene gene2347 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11750 HW43_RS11755 HW43_11425 HW43_RS11755 2386979 2388664 - multidrug ABC transporter ATP-binding protein gene gene2348 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11755 HW43_RS11760 HW43_11430 HW43_RS11760 2388955 2390112 - anaerobic sulfatase maturase gene gene2349 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11760 HW43_RS11765 HW43_11435 HW43_RS11765 2390164 2391846 - Ser-type periplasmic non-aryl sulfatase gene gene2350 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11765 HW43_RS11770 HW43_11440 HW43_RS11770 2392250 2393011 - AraC family transcriptional regulator regulates the cellular response to acid resistance gene gene2351 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11770 HW43_RS11775 HW43_11445 HW43_RS11775 2393086 2393283 - two-component-system connector protein SafA gene gene2352 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11775 HW43_RS11780 HW43_11450 HW43_RS11780 2393531 2395810 - oxidoreductase in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell%3B involved with increased resistance to low pH%3B member of the prokaryotic molybdopterin-containing oxidoreductase family gene gene2353 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11780 HW43_RS11785 HW43_11455 HW43_RS11785 2396144 2397058 - fimbrial protein FimH gene gene2354 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11785 HW43_RS11790 HW43_11460 HW43_RS11790 2397118 2397621 - fimbrial protein gene gene2355 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11790 HW43_RS11795 HW43_11465 HW43_RS11795 2397634 2398164 - fimbrial protein gene gene2356 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11795 HW43_RS11800 HW43_11470 HW43_RS11800 2398178 2400829 - fimbrial protein FimD gene gene2357 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11800 HW43_RS11805 HW43_11475 HW43_RS11805 2400871 2401581 - fimbrial chaperone protein FimC involved in type 1 fimbriae biosynthesis%2C interacts with FimH gene gene2358 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11805 HW43_RS11810 HW43_11480 HW43_RS11810 2401942 2402505 - fimbrial protein gene gene2359 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11810 HW43_RS11815 HW43_25175 HW43_RS11815 2402962 2403141 - transcriptional regulator gene gene2360 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11815 HW43_RS11820 HW43_11490 HW43_RS11820 2403459 2404781 - serine/threonine protein kinase gene gene2361 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11820 HW43_RS11825 HW43_11495 HW43_RS11825 2404781 2405047 - antitoxin HipB gene gene2362 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11825 HW43_RS11830 HW43_11500 HW43_RS11830 2405256 2410676 - outer membrane autotransporter barrel domain-containing protein gene gene2363 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11830 HW43_RS11835 HW43_11505 HW43_RS11835 2411207 2412799 - autoinducer 2 kinase LsrK gene gene2364 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11835 HW43_RS11840 HW43_11510 HW43_RS11840 2412878 2413831 - LsrR family transcriptional regulator regulates the transcription of lsr genes%3B involved in autoinducer 2 uptake%2C biofilm formation and stress responses gene gene2365 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11840 HW43_RS11845 HW43_11515 HW43_RS11845 2414080 2415615 + sugar ABC transporter gene gene2366 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11845 HW43_RS11850 HW43_11520 HW43_RS11850 2415609 2416637 + ABC transporter permease with LsrADB is involved in the transport of autoindiuce 2 gene gene2367 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11850 HW43_RS11855 HW43_11525 HW43_RS11855 2416637 2417629 + autoinducer 2 import system permease LsrD gene gene2368 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11855 HW43_RS11860 HW43_11530 HW43_RS11860 2417641 2418663 + autoinducer 2-binding protein LsrB with lsrACD is involved in the transport of autoinducer 2 into the cell gene gene2369 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11860 HW43_RS11865 HW43_11535 HW43_RS11865 2418690 2419565 + aldolase involved in autoinducer 2 transport and processing gene gene2370 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11865 HW43_RS11870 HW43_11540 HW43_RS11870 2419589 2419879 + autoinducer 2-degrading protein LsrG gene gene2371 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11870 HW43_RS11875 HW43_11545 HW43_RS11875 2419936 2420694 + trans-aconitate 2-methyltransferase catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate gene gene2372 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11875 HW43_RS11880 HW43_11550 HW43_RS11880 2420698 2421612 - hypothetical protein gene gene2373 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11880 HW43_RS11885 HW43_11555 HW43_RS11885 2421819 2423270 - altronate oxidoreductase catalyzes the formation of D-tagaturonate from D-altronate gene gene2374 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11885 HW43_RS11890 HW43_11560 HW43_RS11890 2423497 2424915 - diguanylate cyclase gene gene2375 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11890 HW43_RS11895 HW43_11565 HW43_RS11895 2425054 2425413 - DUF4186 domain-containing protein gene gene2376 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11895 HW43_RS11900 HW43_11570 HW43_RS11900 2425413 2426339 - glutaminase 2 catalyzes the formation of glutamate from glutamine gene gene2377 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11900 HW43_RS11905 HW43_11575 HW43_RS11905 2426403 2427791 - succinate semialdehyde dehydrogenase [NAD(P)+] Sad gene gene2378 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11905 HW43_RS11910 HW43_11580 HW43_RS11910 2427892 2428773 + LysR family transcriptional regulator gene gene2379 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11910 HW43_RS11915 HW43_11585 HW43_RS11915 2428851 2429888 + hypothetical protein gene gene2380 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11915 HW43_RS11920 HW43_11590 HW43_RS11920 2430115 2431305 + arabinose transporter gene gene2381 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11920 HW43_RS11925 HW43_11595 HW43_RS11925 2431330 2431995 - membrane protein gene gene2382 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11925 HW43_RS11930 HW43_11600 HW43_RS11930 2432207 2432641 + MarR family transcriptional regulator Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes gene gene2383 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11930 HW43_RS11935 HW43_11605 HW43_RS11935 2432655 2433044 + MDR efflux pump AcrAB transcriptional activator MarA transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype%3B also activates sodA%2C zwf and micF gene gene2384 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11935 HW43_RS11940 HW43_11610 HW43_RS11940 2433076 2433294 + hypothetical protein gene gene2385 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11940 HW43_RS11945 HW43_11615 HW43_RS11945 2433351 2434790 - 6-phospho-beta-glucosidase gene gene2386 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11945 HW43_RS11950 HW43_11620 HW43_RS11950 2434815 2436488 - porin gene gene2387 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11950 HW43_RS11955 HW43_11625 HW43_RS11955 2436544 2436855 - PTS N'-diacetylchitobiose transporter subunit IIA gene gene2388 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11955 HW43_RS11960 HW43_11630 HW43_RS11960 2436883 2438205 - PTS cellobiose transporter subunit IIC gene gene2389 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11960 HW43_RS11965 HW43_11635 HW43_RS11965 2438320 2438631 - PTS lactose transporter subunit IIB gene gene2390 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11965 HW43_RS11970 HW43_11640 HW43_RS11970 2438830 2439528 + transcriptional regulator gene gene2391 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11970 HW43_RS11975 HW43_11645 HW43_RS11975 2439573 2440472 - O-acetylserine/cysteine export protein gene gene2392 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11975 HW43_RS11980 HW43_11650 HW43_RS11980 2440667 2441854 + transporter YdeF%3B uncharacterized member of the major facilitator superfamily (MFS) of transporters gene gene2393 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11980 HW43_RS11985 HW43_11655 HW43_RS11985 2441981 2442076 + hypothetical protein gene gene2394 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11985 HW43_RS11990 HW43_11660 HW43_RS11990 2442295 2443185 - diguanylate cyclase required for pgaD induction gene gene2395 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11990 HW43_RS11995 HW43_11665 HW43_RS11995 2443440 2443832 - hypothetical protein gene gene2396 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS11995 HW43_RS12000 HW43_11670 HW43_RS12000 2444108 2444626 + hypothetical protein gene gene2397 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12000 HW43_RS12005 HW43_11675 HW43_RS12005 2444671 2446716 - dipeptidyl carboxypeptidase II gene gene2398 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12005 HW43_RS12010 HW43_11680 HW43_RS12010 2446853 2447599 + NADP-dependent 3-hydroxy acid dehydrogenase YdfG NADP(+)-dependent%3B catalyzes the formation of 3-hydroxypropionate from the toxic malonic semialdehyde%2C catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine%3B can also use 3-hydroxybutyrate%2C 3-hydroxy-isobutyrate%2C D-threonine%2C L-allo-threonine%2CD-serine gene gene2399 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12010 HW43_RS12015 HW43_11685 HW43_RS12015 2447688 2448374 + transcriptional regulator gene gene2400 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12015 HW43_RS12020 HW43_11690 HW43_RS12020 2448552 2448755 + hypothetical protein gene gene2401 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12020 HW43_RS12025 HW43_11695 HW43_RS12025 2448791 2450251 - D-mannonate oxidoreductase gene gene2402 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12025 HW43_RS12030 HW43_11700 HW43_RS12030 2450340 2451623 - symporter gene gene2403 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12030 HW43_RS12035 HW43_11705 HW43_RS12035 2451765 2452784 - galactonate oxidoreductase gene gene2404 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12035 HW43_RS12040 HW43_11710 HW43_RS12040 2452796 2454010 - starvation-sensing protein RspA starvation-sensing protein%3B maybe involved in homoserine lactone degradation gene gene2405 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12040 HW43_RS12045 HW43_11715 HW43_RS12045 2454216 2454542 - membrane protein gene gene2406 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12045 HW43_RS12050 HW43_11720 HW43_RS12050 2454677 2455018 + hypothetical protein gene gene2407 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12050 HW43_RS12055 HW43_11725 HW43_RS12055 2455053 2455613 + spermidine N(1)-acetyltransferase catalyzes the formation of N(1)- and N(8)-acetylspermidine from spermidine gene gene2408 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12055 HW43_RS12060 HW43_11730 HW43_RS12060 2455616 2456362 - lipoprotein gene gene2409 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12060 HW43_RS12065 HW43_11735 HW43_RS12065 2456434 2456739 + membrane protein gene gene2410 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12065 HW43_RS12070 HW43_11740 HW43_RS12070 2456938 2459364 + dimethyl sulfoxide reductase subunit A gene gene2411 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12070 HW43_RS12075 HW43_11745 HW43_RS12075 2459452 2461848 + dimethyl sulfoxide reductase subunit A gene gene2412 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12075 HW43_RS12080 HW43_11750 HW43_RS12080 2461859 2462476 + dimethyl sulfoxide reductase oxidoreductase%2C Fe-S subunit%3B terminal electron transfer protein for the reduction of DMSO gene gene2413 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12080 HW43_RS12085 HW43_11755 HW43_RS12085 2462478 2463332 + dimethyl sulfoxide reductase subunit H gene gene2414 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12085 HW43_RS12090 HW43_11760 HW43_RS12090 2463375 2463989 + Tat proofreading chaperone DmsD binds to the twin-arginine signal peptides of certain proteins%2C including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane gene gene2415 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12090 HW43_RS12095 HW43_11765 HW43_RS12095 2464184 2465440 + voltage-gated ClC-type chloride channel ClcB gene gene2416 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12095 HW43_RS12100 HW43_11770 HW43_RS12100 2465393 2466088 - ATP-dependent dethiobiotin synthetase BioD 2 DTB synthetase%3B dethiobiotin synthase%3B involved in production of dethiobiotin from ATP and 7%2C8-diaminononanoate and carbon dioxide%3B contains magnesium gene gene2417 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12100 HW43_RS12105 HW43_11775 HW43_RS12105 2466213 2467433 - transcriptional regulator mlc%2C controls the expression of genes involved in the phosphotransferase and phosphoenolpyruvate systems%2C regulates genes involved in the uptake of sugars gene gene2418 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12105 HW43_RS12110 HW43_11780 HW43_RS12110 2467568 2468461 - LysR family transcriptional regulator gene gene2419 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12110 HW43_RS12115 HW43_11785 HW43_RS12115 2468568 2469821 + hypothetical protein gene gene2420 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12115 HW43_RS12120 HW43_11790 HW43_RS12120 2470218 2470553 + acid-shock protein required for growth and survival under moderately acid conditions gene gene2421 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12120 HW43_RS12125 HW43_25180 HW43_RS12125 2470646 2470729 + hypothetical protein gene gene2422 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12125 HW43_RS12130 HW43_11800 HW43_RS12130 2470829 2471650 + serine protease gene gene2423 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12130 HW43_RS12135 HW43_11805 HW43_RS12135 2471689 2472018 - spermidine export protein MdtI with MdtJ is involved in resistance to deoxycholate%2C nalidixic acid%2C fosfomycin%2C and SDS gene gene2424 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12135 HW43_RS12140 HW43_11810 HW43_RS12140 2472005 2472370 - spermidine export protein MdtJ with MdtI is involved in resistance to deoxycholate%2C nalidixic acid%2C fosfomycin%2C and SDS gene gene2425 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12140 HW43_RS12145 HW43_11815 tqsA tqsA 2472782 2473816 + pheromone autoinducer 2 transporter transport of quorum-sensing signal%3B mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes gene gene2426 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12145 HW43_RS12150 HW43_11820 pntB pntB 2473841 2475229 - NAD(P) transhydrogenase subunit beta catalyzes reversible transfer of hydride ion equivalent between NAD and NADP%3B membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane%3B forms a tetramer composed of two alpha and 2 beta subunits%3B AB-stereospecific enzyme gene gene2427 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12150 HW43_RS12155 HW43_11825 pntA pntA 2475240 2476772 - NAD(P) transhydrogenase subunit alpha forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane%3B involved in catalyzing transfer of hydride ion equivalents between NAD and NADP%3B stereospecific (AB-specific)%3B functions as a proton pump by translocating protons from cytoplasm to periplasm gene gene2428 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12155 HW43_RS12160 HW43_11830 HW43_RS12160 2477296 2478240 + hypothetical protein gene gene2429 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12160 HW43_RS12165 HW43_11835 HW43_RS12165 2478426 2479808 + arginine/ornithine antiporter transporter gene gene2430 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12165 HW43_RS12170 HW43_11840 HW43_RS12170 2479845 2480567 + dihydrofolate reductase FolM gene gene2431 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12170 HW43_RS12175 HW43_11845 HW43_RS12175 2480564 2480899 - hypothetical protein gene gene2432 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12175 HW43_RS12180 HW43_11850 HW43_RS12180 2481028 2481747 + two-component system response regulator response regulator in two-component regulatory system with RstB gene gene2433 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12180 HW43_RS12185 HW43_11855 HW43_RS12185 2481751 2483052 + two-component system sensor histidine kinase gene gene2434 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12185 HW43_RS12190 HW43_11860 HW43_RS12190 2483128 2484057 + DNA replication terminus site-binding protein binds to DNA replication terminator sequences to prevent passage of replication forks gene gene2435 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12190 HW43_RS12195 HW43_11865 fumC fumC 2484054 2485457 - fumarate hydratase class II family (does not require metal)%3B tetrameric enzyme%3B fumarase C%3B reversibly converts (S)-malate to fumarate and water%3B functions in the TCA cycle gene gene2436 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12195 HW43_RS12200 HW43_11870 HW43_RS12200 2485600 2487246 - fumarate hydratase catalyzes the formation of malate from fumerate gene gene2437 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12200 HW43_RS12205 HW43_11875 HW43_RS12205 2487445 2488620 + mannose-6-phosphate isomerase catalyzes the formation of of fructose 6-phosphate from mannose 6-phosphate gene gene2438 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12205 HW43_RS12210 HW43_11880 HW43_RS12210 2488721 2490229 + hypothetical protein gene gene2439 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12210 HW43_RS12215 HW43_11885 HW43_RS12215 2490274 2491539 - porin gene gene2440 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12215 HW43_RS12220 HW43_11890 HW43_RS12220 2491578 2492951 - glucuronide transporter gene gene2441 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12220 HW43_RS12225 HW43_11895 HW43_RS12225 2492948 2494759 - beta-D-glucuronidase gene gene2442 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12225 HW43_RS12230 HW43_11900 HW43_RS12230 2495147 2495737 - transcriptional regulator gene gene2443 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12230 HW43_RS12235 HW43_11905 HW43_RS12235 2495966 2496733 - 7-alpha-hydroxysteroid dehydrogenase Acts on the hydroxyl group at position 7 of the steroid frame gene gene2444 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12235 HW43_RS12240 HW43_11910 HW43_RS12240 2496845 2497873 - LacI family transcriptional regulator regulates malXY which are involved in maltose-glucose transport gene gene2445 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12240 HW43_RS12245 HW43_11915 HW43_RS12245 2498048 2499640 + PTS maltose- and glucose EIICB component phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%3B catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane%3B component IIB catalyzes the phosphorylation of the sugar molecule%3B IIC forms the translocation channel and contains the substrate specific binding site gene gene2446 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12245 HW43_RS12250 HW43_11920 HW43_RS12250 2499650 2500822 + aminotransferase catalyzes the formation of homocysteine and pyruvate from cystathionine%3B also acts a a negative regulator for the mal regulon but interacting with the transcriptional activator MalT gene gene2447 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12250 HW43_RS12255 HW43_11925 HW43_RS12255 2500926 2501927 + adenosine deaminase gene gene2448 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12255 HW43_RS12260 HW43_11930 HW43_RS12260 2501962 2503002 - oxidoreductase gene gene2449 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12260 HW43_RS12265 HW43_25185 HW43_RS12265 2503245 2503370 + divisome-associated membrane protein Blr gene gene2450 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12265 HW43_RS12270 HW43_11940 HW43_RS12270 2503643 2503858 + nucleoid-associated protein YdgT%3B in E. coli%2C when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC%3B seems to play a role in optimizing the activity of oriC%3B non-essential%3B Hha protein paralog%3B in an hha mutant background%2C cnu is overexpressed and can compensate hha-induced phenotypes gene gene2451 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12270 HW43_RS12275 HW43_11945 HW43_RS12275 2503944 2504384 + membrane protein gene gene2452 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12275 HW43_RS12280 HW43_11950 HW43_RS12280 2504461 2505042 + electron transport complex subunit RsxA gene gene2453 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12280 HW43_RS12285 HW43_11955 HW43_RS12285 2505042 2505620 + electron transport complex subunit RsxB part of membrane-bound complex thought to be involved in electron transport to nitrogen gene gene2454 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12285 HW43_RS12290 HW43_11960 HW43_RS12290 2505613 2507835 + electron transporter RsxC part of membrane-bound complex thought to be involved in electron transport to nitrogen gene gene2455 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12290 HW43_RS12295 HW43_11965 rnfD rnfD 2507836 2508894 + electron transporter RnfG RnfD%3B RsxD%3B required for nitrogen fixation in Rhodobacter capsulatus%3B part of a membrane-bound complex thought to be involved in electron transport to nitrogenase%3B in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents gene gene2456 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12295 HW43_RS12300 HW43_11970 HW43_RS12300 2508898 2509518 + electron transport complex subunit RsxG part of membrane-bound complex hought to be involved in electron transport to nitrogen gene gene2457 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12300 HW43_RS12305 HW43_11975 HW43_RS12305 2509522 2510217 + electron transporter RsxE gene gene2458 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12305 HW43_RS12310 HW43_11980 HW43_RS12310 2510217 2510852 + endonuclease III DNA-(apurinic or apyrimidinic site) lyase%3B has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity%3B removed damaged DNA at cytosines%2C thymines and guanines gene gene2459 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12310 HW43_RS12315 HW43_11985 HW43_RS12315 2510980 2511180 + hypothetical protein gene gene2460 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12315 HW43_RS12320 HW43_11990 tppB tppB 2511463 2512965 + dipeptide and tripeptide permease A mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium%3B member of proton-dependent oligopeptide transport (POT) system family%3B in Escherichia coli this gene is regulated by OmpR although not via osmoregulation gene gene2461 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12320 HW43_RS12325 HW43_11995 HW43_RS12325 2513071 2513676 + glutathione S-transferase gene gene2462 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12325 HW43_RS12330 HW43_12000 HW43_RS12330 2513720 2514580 - pyridoxamine kinase catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal gene gene2463 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12330 HW43_RS12335 HW43_12005 HW43_RS12335 2514642 2515916 - tyrosine--tRNA ligase gene gene2464 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12335 HW43_RS12340 HW43_12010 HW43_RS12340 2516045 2516701 - pyridoxine/pyridoxamine 5'-phosphate oxidase catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate gene gene2465 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12340 HW43_RS12345 HW43_12015 HW43_RS12345 2516760 2517089 - lysozyme inhibitor MliC%3B membrane-bound lysozyme inhibitor of c-type lysozyme gene gene2466 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12345 HW43_RS12350 HW43_12020 anmK anmK 2517187 2518296 - anhydro-N-acetylmuramic acid kinase catalyzes hydrolysis of 1%2C6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate%3B involved in murein recycling gene gene2467 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12350 HW43_RS12355 HW43_12025 HW43_RS12355 2518570 2519037 + hypothetical protein gene gene2468 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12355 HW43_RS12360 HW43_12030 HW43_RS12360 2519084 2519518 - SlyA family transcriptional regulator Transcription regulator that can both activate or repress expression gene gene2469 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12360 HW43_RS12365 HW43_12035 HW43_RS12365 2519719 2519955 + membrane protein gene gene2470 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12365 HW43_RS12370 HW43_12040 HW43_RS12370 2519958 2520815 + membrane protein gene gene2471 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12370 HW43_RS12375 HW43_12045 HW43_RS12375 2520815 2522827 + fusaric acid resistance protein gene gene2472 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12375 HW43_RS12380 HW43_12050 HW43_RS12380 2522828 2523349 - superoxide dismutase [Cu-Zn] SodC%3B copper and zinc binding%3B converts superoxide radicals to hydrogen peroxide and water gene gene2473 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12380 HW43_RS12385 HW43_12055 HW43_RS12385 2523430 2524326 - oxidoreductase gene gene2474 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12385 HW43_RS12390 HW43_25190 HW43_RS12390 2524375 2524614 - DUF1289 domain-containing protein gene gene2475 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12390 HW43_RS12395 HW43_12065 HW43_RS12395 2524717 2525316 + transcriptional regulator represses nemA which is involved in degradation of N-ethylmaleimide gene gene2476 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12395 HW43_RS12400 HW43_12070 HW43_RS12400 2525353 2526450 + N-ethylmaleimide reductase FMN-linked%3B catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide gene gene2477 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12400 HW43_RS12405 HW43_12075 HW43_RS12405 2526531 2526938 + lactoylglutathione lyase Ni-dependent%3B catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione gene gene2478 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12405 HW43_RS12410 HW43_12080 HW43_RS12410 2527041 2527688 + ribonuclease T Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) gene gene2479 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12410 HW43_RS12415 HW43_12085 HW43_RS12415 2527781 2532397 + ATP-dependent helicase Lhr similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases%3B longest known protein in E. coli gene gene2480 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12415 HW43_RS12420 HW43_12090 HW43_RS12420 2532448 2532795 - glutaredoxin gene gene2481 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12420 HW43_RS12425 HW43_12095 HW43_RS12425 2533129 2533944 + murein DD-endopeptidase MepH gene gene2482 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12425 HW43_RS12430 HW43_12100 HW43_RS12430 2534072 2534653 + superoxide dismutase [Fe] SodB%3B iron binding%3B present under aerobic and anaerobic conditions%3B destroys free radicals gene gene2483 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12430 HW43_RS12435 HW43_12105 HW43_RS12435 2534799 2535968 - transporter gene gene2484 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12435 HW43_RS12440 HW43_25195 HW43_RS12440 2536134 2536223 - stress response membrane gene gene2485 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12440 HW43_RS12445 HW43_12115 HW43_RS12445 2536522 2537547 + PurR family transcriptional regulator binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis%3B is involved in regulation of purB%2C purC%2C purEK%2C purHD%2C purL%2C purMN and guaBA expression%3B binds hypoxanthine and guanine as inducers gene gene2486 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12445 HW43_RS12450 HW43_12120 HW43_RS12450 2537544 2538476 - LysR family transcriptional regulator gene gene2487 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12450 HW43_RS12455 HW43_12125 HW43_RS12455 2538589 2539800 + Bcr/CflA family drug resistance efflux transporter uncharacterized member of the major facilitator superfamily (MFS) gene gene2488 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12455 HW43_RS12460 HW43_12130 HW43_RS12460 2540091 2541239 + cyclopropane fatty acyl phospholipid synthase catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge gene gene2489 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12460 HW43_RS12465 HW43_12135 HW43_RS12465 2541279 2541920 - riboflavin synthase catalyzes the formation of riboflavin from 6%2C7-dimethyl-8-(1-D-ribityl)lumazine gene gene2490 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12465 HW43_RS12470 HW43_12140 HW43_RS12470 2542135 2543508 + multidrug resistance protein MdtK NorM%3B MdtK%3B functions as a Na(+)/drug antiporter%3B inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones gene gene2491 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12470 HW43_RS12475 HW43_12145 HW43_RS12475 2543549 2544805 - hypothetical protein gene gene2492 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12475 HW43_RS12480 HW43_12150 HW43_RS12480 2545113 2545189 + tRNA-Val tRNA gene2493 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12480 HW43_RS12485 HW43_12155 HW43_RS12485 2545194 2545270 + tRNA-Val tRNA gene2494 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12485 HW43_RS12490 HW43_12160 HW43_RS12490 2545378 2545683 + monooxygenase gene gene2495 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12490 HW43_RS12495 HW43_12165 HW43_RS12495 2545809 2547413 + hypothetical protein gene gene2496 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12495 HW43_RS12500 HW43_12170 HW43_RS12500 2547425 2548237 - hypothetical protein gene gene2497 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12500 HW43_RS12505 HW43_12175 HW43_RS12505 2548241 2549026 - thiosulfate reductase cytochrome B gene gene2498 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12505 HW43_RS12510 HW43_12180 HW43_RS12510 2549023 2549691 - 4Fe-4S ferredoxin gene gene2499 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12510 HW43_RS12515 HW43_12185 HW43_RS12515 2549755 2550393 - hypothetical protein gene gene2500 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12515 HW43_RS12520 HW43_12190 HW43_RS12520 2550406 2552508 - oxidoreductase gene gene2501 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12520 HW43_RS12525 HW43_12195 HW43_RS12525 2552529 2553155 - 4Fe-4S ferredoxin gene gene2502 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12525 HW43_RS12530 HW43_12200 HW43_RS12530 2553611 2553820 - hypothetical protein gene gene2503 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12530 HW43_RS12535 HW43_12205 HW43_RS12535 2554377 2555789 + pyruvate kinase catalyzes the formation of phosphoenolpyruvate from pyruvate gene gene2504 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12535 HW43_RS12540 HW43_12210 HW43_RS12540 2556100 2556336 + murein lipoprotein major outer membrane lipoprotein%3B interacts with peptidoglycan to maintain the integrity of the cell envelope gene gene2505 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12540 HW43_RS12545 HW43_12215 HW43_RS12545 2556400 2557404 - murein transpeptidase catalyzes the formation of a meso-diaminopimelyl-3-a meso-diaminopimelyl-3 cross-link in peptidoglycan synthesis gene gene2506 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12545 HW43_RS12550 HW43_12220 HW43_RS12550 2557553 2557969 - cysteine desulfuration protein SufE Acts with SufS to catalyze the formation of L-alanine from L-cysteine gene gene2507 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12550 HW43_RS12555 HW43_12225 HW43_RS12555 2557982 2559202 - cysteine desulfurase gene gene2508 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12555 HW43_RS12560 HW43_12230 HW43_RS12560 2559199 2560470 - Fe-S cluster assembly protein SufD with SufBC activates cysteine desulfurase SufS gene gene2509 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12560 HW43_RS12565 HW43_12235 sufC sufC 2560445 2561191 - Fe-S cluster assembly ATPase SufC part of SUF system involved in inserting iron-sulfur clusters into proteins%3B in Escherichia coli this protein forms a complex with SufBD%3B the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE gene gene2510 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12565 HW43_RS12570 HW43_12240 HW43_RS12570 2561201 2562688 - cysteine desulfurase activator complex subunit SufB with SufCD activates cysteine desulfurase SufS gene gene2511 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12570 HW43_RS12575 HW43_12245 sufA sufA 2562697 2563065 - protein SufA functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]%3B [4Fe-4S]) are assembled%3B forms a homodimer%3B similar to IscA protein gene gene2512 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12575 HW43_RS12580 HW43_12250 HW43_RS12580 2563613 2563801 - hypothetical protein gene gene2513 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12580 HW43_RS12585 HW43_12255 HW43_RS12585 2563901 2564311 - 1%2C4-dihydroxy-2-naphthoyl-CoA hydrolase required for efficient enterobactin production gene gene2514 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12585 HW43_RS12590 HW43_12260 HW43_RS12590 2564308 2567364 - membrane protein gene gene2515 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12590 HW43_RS12595 HW43_12265 HW43_RS12595 2567753 2568865 + hypothetical protein YdiK%3B inner membrane protein%3B ydiK promoter presents a PurR sequence%2C suggesting that its expression is purine-regulated%3B unknown function gene gene2516 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12595 HW43_RS12600 HW43_12270 HW43_RS12600 2569294 2569650 + HTH domain DNA-binding protein gene gene2517 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12600 HW43_RS12605 HW43_12275 HW43_RS12605 2569750 2570964 + transporter gene gene2518 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12605 HW43_RS12610 HW43_12280 HW43_RS12610 2571191 2572456 + transporter gene gene2519 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12610 HW43_RS12615 HW43_12285 HW43_RS12615 2572468 2573334 + quinate/shikimate dehydrogenase YdiB%3B quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate gene gene2520 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12615 HW43_RS12620 HW43_12290 HW43_RS12620 2573365 2574123 + 3-dehydroquinate dehydratase gene gene2521 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12620 HW43_RS12625 HW43_12295 HW43_RS12625 2574267 2575862 + hypothetical protein gene gene2522 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12625 HW43_RS12630 HW43_12300 HW43_RS12630 2575876 2577027 + acyl-CoA dehydrogenase may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain gene gene2523 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12630 HW43_RS12635 HW43_12305 HW43_RS12635 2577070 2577981 - transcriptional regulator gene gene2524 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12635 HW43_RS12640 HW43_25200 HW43_RS12640 2578084 2578260 - hypothetical protein gene gene2525 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12640 HW43_RS12645 HW43_12310 HW43_RS12645 2578297 2579061 + electron transfer flavoprotein subunit gene gene2526 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12645 HW43_RS12650 HW43_12315 fixB fixB 2579081 2580019 + electron transfer flavoprotein subunit alpha involved in electron transfer during carnitine metabolism gene gene2527 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12650 HW43_RS12655 HW43_12320 HW43_RS12655 2580075 2581364 + oxidoreductase FixC FAD/NAD(P)-binding domain%3B possibly part of an electron transfer system required for anaerobic carnitine reduction gene gene2528 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12655 HW43_RS12660 HW43_12325 HW43_RS12660 2581361 2581654 + ferredoxin ydiT gene gene2529 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12660 HW43_RS12665 HW43_12330 HW43_RS12665 2581711 2583357 + short chain acyl-CoA synthetase acts in anaerobic beta-oxidation of fatty acids%3B possible ligase/synthase involved in anaerobic growth on fatty acids gene gene2530 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12665 HW43_RS12670 HW43_12335 HW43_RS12670 2583414 2585792 - phosphoenolpyruvate synthase catalyzes the formation of phosphoenolpyruvate from pyruvate gene gene2531 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12670 HW43_RS12675 HW43_25205 HW43_RS12675 2585846 2586013 - hypothetical protein gene gene2532 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12675 HW43_RS12680 HW43_12340 HW43_RS12680 2586125 2586958 + phosphoenolpyruvate synthase regulatory protein gene gene2533 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12680 HW43_RS12685 HW43_12345 HW43_RS12685 2587115 2588161 + phospho-2-dehydro-3-deoxyheptonate aldolase Trp-sensitive gene gene2534 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12685 HW43_RS12690 HW43_12350 HW43_RS12690 2588293 2588484 + hemin uptake protein HemP homolog gene gene2535 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12690 HW43_RS12695 HW43_12355 HW43_RS12695 2588488 2589924 - hypothetical protein gene gene2536 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12695 HW43_RS12700 HW43_12360 HW43_RS12700 2589987 2590699 - cyclic di-GMP regulator CdgR gene gene2537 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12700 HW43_RS12705 HW43_12365 HW43_RS12705 2590946 2591410 - lipoprotein gene gene2538 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12705 HW43_RS12710 HW43_12370 HW43_RS12710 2591488 2592237 - vitamin B12 import ATP-binding protein BtuD ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell gene gene2539 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12710 HW43_RS12715 HW43_12375 btuE btuE 2592237 2592788 - glutathione peroxidase similar to glutathione peroxidase%3B member of the btuCED operon which is required for vitamin B12 transport across the inner membrane gene gene2540 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12715 HW43_RS12720 HW43_12380 HW43_RS12720 2592851 2593831 - vitamin B12 import system permease BtuC with BtuD and BtuF transports vitamin B12 into the cell gene gene2541 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12720 HW43_RS12725 HW43_12385 ihfA ihfA 2593932 2594231 - integration host factor subunit alpha This protein is one of the two subunits of integration host factor%2C a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control gene gene2542 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12725 HW43_RS12730 HW43_12390 pheT pheT 2594236 2596623 - phenylalanine--tRNA ligase subunit beta catalyzes a two-step reaction%2C first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B forms a tetramer of alpha(2)beta(2)%3B binds two magnesium ions per tetramer%3B type 2 subfamily gene gene2543 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12730 HW43_RS12735 HW43_12395 HW43_RS12735 2596638 2597621 - phenylalanine--tRNA ligase subunit alpha gene gene2544 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12735 HW43_RS12740 HW43_25210 HW43_RS12740 2597735 2597829 - hypothetical protein gene gene2545 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12740 HW43_RS12745 HW43_12400 rplT rplT 2598071 2598427 - 50S ribosomal protein L20 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit gene gene2546 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12745 HW43_RS12750 HW43_12405 HW43_RS12750 2598480 2598677 - 50S ribosomal protein L35 gene gene2547 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12750 HW43_RS12755 HW43_25215 HW43_RS12755 2598774 2599316 - translation initiation factor IF-3 gene gene2548 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12755 HW43_RS12760 HW43_12415 thrS thrS 2599320 2601248 - threonine--tRNA ligase catalyzes a two-step reaction%2C first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) gene gene2549 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12760 HW43_RS12765 HW43_12420 HW43_RS12765 2601772 2602887 + enterotoxin gene gene2550 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12765 HW43_RS12770 HW43_12425 HW43_RS12770 2602990 2603670 + hypothetical protein gene gene2551 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12770 HW43_RS12775 HW43_25220 HW43_RS12775 2603846 2603953 + hypothetical protein gene gene2552 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12775 HW43_RS12780 HW43_12435 HW43_RS12780 2604006 2604764 - membrane protein gene gene2553 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12780 HW43_RS12785 HW43_12440 HW43_RS12785 2605051 2605980 + 6-phosphofructokinase gene gene2554 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12785 HW43_RS12790 HW43_12445 HW43_RS12790 2606081 2606371 + hypothetical protein gene gene2555 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12790 HW43_RS12795 HW43_12450 HW43_RS12795 2606477 2607337 + hypothetical protein gene gene2556 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12795 HW43_RS12800 HW43_12455 HW43_RS12800 2607378 2607914 - membrane protein gene gene2557 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12800 HW43_RS12805 HW43_12460 HW43_RS12805 2608061 2608729 + 2-deoxyglucose-6-phosphate phosphatase YniC%3B catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate%2C mannose 6-phosphate and p-nitrophenyl phosphate gene gene2558 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12805 HW43_RS12810 HW43_12465 HW43_RS12810 2608892 2609482 + hypothetical protein gene gene2559 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12810 HW43_RS12815 HW43_12470 HW43_RS12815 2609615 2611006 + L-cystine transporter tcyP gene gene2560 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12815 HW43_RS12820 HW43_25225 HW43_RS12820 2611010 2611813 - hypothetical protein gene gene2561 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12820 HW43_RS12825 HW43_12480 HW43_RS12825 2612102 2612344 - cell division activator CedA gene gene2562 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12825 HW43_RS12830 HW43_12485 katE katE 2612548 2614809 + catalase HPII Catalase HPII%3B monofunctional catalase that decomposes hydrogen peroxide into water and oxygen%3B serves to protect cells from the toxic effects of hydrogen peroxide gene gene2563 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12830 HW43_RS12835 HW43_12490 HW43_RS12835 2614856 2615614 - hypothetical protein gene gene2564 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12835 HW43_RS12840 HW43_12495 HW43_RS12840 2615627 2616979 - diacetylchitobiose-6-phosphate hydrolase catalyzes the fromation of N-acetyl-D-glucosamine and N-acetyl-D-glucosamine-6-phosphate from diacetylchitobiose-6-phosphate gene gene2565 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12840 HW43_RS12845 HW43_12500 HW43_RS12845 2617084 2617923 - transcriptional regulator represses the celABCDF-ydjC operon involved in carbon uptake gene gene2566 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12845 HW43_RS12850 HW43_12505 HW43_RS12850 2617934 2618284 - N%2CN'-diacetylchitobiose-specific phosphotransferase enzyme IIA component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B involved N%2CN'-diacetylchitobiose transport%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene2567 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12850 HW43_RS12855 HW43_12510 HW43_RS12855 2618335 2619693 - N%2CN'-diacetylchitobiose permease IIC component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B involved in N%2CN'-diacetylchitobiose transport%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene2568 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12855 HW43_RS12860 HW43_12515 HW43_RS12860 2619778 2620098 - N%2CN'-diacetylchitobiose-specific phosphotransferase enzyme IIB component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B involved in N%2CN'-diacetylchitobiose transport%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene2569 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12860 HW43_RS12865 HW43_12520 HW43_RS12865 2620397 2620735 - osmotically-inducible lipoprotein E osmotically-inducible lipoprotein E%3B activator of ntr-like gene protein gene gene2570 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12865 HW43_RS12870 HW43_12525 nadE nadE 2620937 2621764 + nH(3)-dependent NAD+ synthetase catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP%3B ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one%3B forms homodimers gene gene2571 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12870 HW43_RS12875 HW43_25230 HW43_RS12875 2621733 2621924 - hypothetical protein gene gene2572 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12875 HW43_RS12880 HW43_12530 HW43_RS12880 2621994 2622881 + excinuclease cho 3' incision activity%3B acts with UvrC gene gene2573 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12880 HW43_RS12885 HW43_12535 HW43_RS12885 2622841 2623416 - protein Ves gene gene2574 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12885 HW43_RS12890 HW43_12540 HW43_RS12890 2623619 2624104 - hypothetical protein periplasmic protein induced by stress response via Cpx and BaeSR system%3B similar to CpxP gene gene2575 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12890 HW43_RS12895 HW43_12545 HW43_RS12895 2624434 2625402 - succinylglutamate desuccinylase catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism gene gene2576 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12895 HW43_RS12900 HW43_12550 HW43_RS12900 2625395 2626738 - N-succinylarginine dihydrolase catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine%2C ammonia and carbon dioxide in arginine degradation gene gene2577 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12900 HW43_RS12905 HW43_12555 astD astD 2626735 2628213 - N-succinylglutamate 5-semialdehyde dehydrogenase a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity%3B converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH gene gene2578 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12905 HW43_RS12910 HW43_12560 HW43_RS12910 2628210 2629244 - arginine N-succinyltransferase gene gene2579 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12910 HW43_RS12915 HW43_12565 HW43_RS12915 2629241 2630461 - succinylornithine aminotransferase catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate%3B also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate gene gene2580 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12915 HW43_RS12920 HW43_12575 HW43_RS12920 2630907 2631713 + exodeoxyribonuclease III gene gene2581 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12920 HW43_RS12925 HW43_12580 HW43_RS12925 2631880 2632590 + membrane protein gene gene2582 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12925 HW43_RS12930 HW43_12585 HW43_RS12930 2632595 2633272 + hypothetical protein gene gene2583 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12930 HW43_RS12935 HW43_12590 HW43_RS12935 2633287 2633994 + membrane protein gene gene2584 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12935 HW43_RS12940 HW43_12595 HW43_RS12940 2633994 2634542 + hypothetical protein gene gene2585 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12940 HW43_RS12945 HW43_12600 HW43_RS12945 2634552 2635718 + hypothetical protein gene gene2586 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12945 HW43_RS12950 HW43_12605 HW43_RS12950 2635691 2637226 + thiamine ABC transporter permease gene gene2587 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12950 HW43_RS12955 HW43_12610 HW43_RS12955 2637226 2637879 + sulfate ABC transporter ATP-binding protein gene gene2588 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12955 HW43_RS12960 HW43_12615 HW43_RS12960 2637946 2639253 + thiosulfate sulfurtransferase gene gene2589 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12960 HW43_RS12965 HW43_12620 HW43_RS12965 2639262 2639882 - hypothetical protein gene gene2590 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12965 HW43_RS12970 HW43_12625 HW43_RS12970 2639969 2640376 + pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase gene gene2591 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12970 HW43_RS12975 HW43_12630 HW43_RS12975 2640342 2640614 - hypothetical protein gene gene2592 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12975 HW43_RS12980 HW43_12635 HW43_RS12980 2640850 2642193 + glutamate dehydrogenase converts 2-oxoglutarate to glutamate%3B in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction%3B uses NADPH%3B forms a homohexamer gene gene2593 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12980 HW43_RS12985 HW43_12640 HW43_RS12985 2642310 2643351 - hypothetical protein gene gene2594 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12985 HW43_RS12990 HW43_12645 HW43_RS12990 2643479 2645440 - DNA topoisomerase III decatenates replicating daughter chromosomes gene gene2595 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12990 HW43_RS12995 HW43_12650 HW43_RS12995 2645445 2646488 - selenophosphate synthase catalyzes the formation of selenophosphate from selenide and ATP gene gene2596 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS12995 HW43_RS13000 HW43_25235 HW43_RS13000 2646430 2646579 - hypothetical protein gene gene2597 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13000 HW43_RS13005 HW43_12655 HW43_RS13005 2646605 2647156 - oxidoreductase gene gene2598 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13005 HW43_RS13010 HW43_25240 HW43_RS13010 2647210 2647374 + hypothetical protein gene gene2599 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13010 HW43_RS13015 HW43_12660 HW43_RS13015 2647317 2649173 + signal peptide peptidase SppA SppA%3B catalyzes the degradation of cleaved signal peptides%3B essential to maintain secretion of mature proteins across the membrane gene gene2600 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13015 HW43_RS13020 HW43_12665 ansA ansA 2649340 2650356 + L-asparaginase 1 converts asparagine to aspartate and ammonia gene gene2601 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13020 HW43_RS13025 HW43_12670 HW43_RS13025 2650367 2651008 + nicotinamidase/pyrazinamidase catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide gene gene2602 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13025 HW43_RS13030 HW43_12675 HW43_RS13030 2651101 2652459 - MFS transporter gene gene2603 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13030 HW43_RS13035 HW43_12680 HW43_RS13035 2652576 2653334 - DeoR family transcriptional regulator gene gene2604 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13035 HW43_RS13040 HW43_12685 HW43_RS13040 2653471 2654451 - oxidoreductase gene gene2605 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13040 HW43_RS13045 HW43_12690 HW43_RS13045 2654461 2655408 - kinase gene gene2606 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13045 HW43_RS13050 HW43_12695 HW43_RS13050 2655413 2656249 - hypothetical protein gene gene2607 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13050 HW43_RS13055 HW43_12700 HW43_RS13055 2656270 2657313 - alcohol dehydrogenase gene gene2608 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13055 HW43_RS13060 HW43_12705 HW43_RS13060 2657330 2658709 - transporter gene gene2609 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13060 HW43_RS13065 HW43_12710 HW43_RS13065 2658736 2659812 - oxidoreductase gene gene2610 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13065 HW43_RS13070 HW43_12715 HW43_RS13070 2660182 2660454 - hypothetical protein gene gene2611 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13070 HW43_RS13075 HW43_12720 HW43_RS13075 2660496 2660909 - peptide methionine sulfoxide reductase MsrB gene gene2612 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13075 HW43_RS13080 HW43_12725 HW43_RS13080 2661251 2662246 + glyceraldehyde-3-phosphate dehydrogenase gene gene2613 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13080 HW43_RS13085 HW43_12730 HW43_RS13085 2662330 2663214 + aldose 1-epimerase gene gene2614 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13085 HW43_RS13090 HW43_12735 HW43_RS13090 2663265 2664119 - oxidoreductase gene gene2615 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13090 HW43_RS13095 HW43_12740 HW43_RS13095 2664209 2664955 - MltA-interacting protein scaffolding protein for the murein polymerase MrcB and the lytic transglycosylase MltA gene gene2616 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13095 HW43_RS13100 HW43_12745 HW43_RS13100 2665391 2667325 + protein kinase endogenous substrate unidentified%3B autokinase gene gene2617 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13100 HW43_RS13105 HW43_12750 HW43_RS13105 2667438 2668721 + hypothetical protein gene gene2618 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13105 HW43_RS13110 HW43_12755 HW43_RS13110 2669009 2670343 + membrane protein gene gene2619 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13110 HW43_RS13115 HW43_12760 HW43_RS13115 2670524 2672014 + diguanylate cyclase gene gene2620 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13115 HW43_RS13120 HW43_12765 HW43_RS13120 2672057 2672560 + hypothetical protein gene gene2621 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13120 HW43_RS13125 HW43_25245 HW43_RS13125 2672561 2672713 - hypothetical protein gene gene2622 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13125 HW43_RS13130 HW43_12775 HW43_RS13130 2672835 2673281 + membrane protein gene gene2623 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13130 HW43_RS13135 HW43_12780 HW43_RS13135 2673238 2674059 - AraC family transcriptional regulator gene gene2624 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13135 HW43_RS13140 HW43_12785 HW43_RS13140 2674156 2675337 + membrane protein gene gene2625 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13140 HW43_RS13145 HW43_12790 HW43_RS13145 2675392 2675739 + hypothetical protein gene gene2626 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13145 HW43_RS13150 HW43_12795 HW43_RS13150 2675761 2676015 - hypothetical protein gene gene2627 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13150 HW43_RS13155 HW43_12800 HW43_RS13155 2676198 2677223 + diguanylate cyclase gene gene2628 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13155 HW43_RS13160 HW43_25250 HW43_RS13160 2677256 2677354 + hypothetical protein gene gene2629 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13160 HW43_RS13165 HW43_12805 HW43_RS13165 2677490 2677738 - membrane protein gene gene2630 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13165 HW43_RS13170 HW43_12810 HW43_RS13170 2677965 2679113 - transposase gene gene2631 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13170 HW43_RS13175 HW43_25255 HW43_RS13175 2679181 2679672 + transposase gene gene2632 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13175 HW43_RS13180 HW43_12815 HW43_RS13180 2679628 2679816 - hypothetical protein gene gene2633 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13180 HW43_RS13185 HW43_12820 HW43_RS13185 2679820 2680179 - hypothetical protein gene gene2634 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13185 HW43_RS13190 HW43_12825 HW43_RS13190 2680352 2680990 - leucine efflux protein gene gene2635 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13190 HW43_RS13195 HW43_12830 HW43_RS13195 2681117 2682040 - LysR family transcriptional regulator gene gene2636 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13195 HW43_RS13200 HW43_12835 HW43_RS13200 2682143 2683228 + tartrate dehydrogenase gene gene2637 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13200 HW43_RS13205 HW43_12840 HW43_RS13205 2683479 2685089 + transporter member of the betaine%2C carnitine%2C choline transporter (BCCT) family%3B unknown function gene gene2638 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13205 HW43_RS13210 HW43_12845 HW43_RS13210 2685121 2686245 + ring hydroxylating dioxygenase subunit alpha gene gene2639 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13210 HW43_RS13215 HW43_12850 HW43_RS13215 2686301 2687266 + dioxygenase subunit beta gene gene2640 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13215 HW43_RS13220 HW43_12855 HW43_RS13220 2687320 2688435 - ribonuclease D gene gene2641 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13220 HW43_RS13225 HW43_12860 HW43_RS13225 2688517 2690235 - long-chain fatty acid--CoA ligase Activates fatty acids by binding to coenzyme A gene gene2642 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13225 HW43_RS13230 HW43_12865 HW43_RS13230 2690407 2690988 - Slp family lipoprotein%2C RpoE-regulated gene gene2643 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13230 HW43_RS13235 HW43_12870 HW43_RS13235 2691028 2691723 - tRNA threonylcarbamoyladenosine biosynthesis protein TsaB gene gene2644 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13235 HW43_RS13240 HW43_12875 HW43_RS13240 2691781 2693691 - ATP-dependent helicase gene gene2645 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13240 HW43_RS13245 HW43_12880 HW43_RS13245 2693823 2694167 + hypothetical protein gene gene2646 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13245 HW43_RS13250 HW43_12885 HW43_RS13250 2694590 2694889 + hypothetical protein gene gene2647 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13250 HW43_RS13255 HW43_12890 HW43_RS13255 2695009 2695188 - hypothetical protein gene gene2648 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13255 HW43_RS13260 HW43_12895 pabB pabB 2695262 2696623 + aminodeoxychorismate synthase component I para-aminobenzoate synthase component 1%3B catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and L-glutamine gene gene2649 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13260 HW43_RS13265 HW43_12900 HW43_RS13265 2696627 2697205 + NUDIX hydrolase gene gene2650 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13265 HW43_RS13270 HW43_12905 HW43_RS13270 2697389 2698753 + L-serine dehydratase 1 catalyzes the formation of pyruvate from serine gene gene2651 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13270 HW43_RS13275 HW43_12910 HW43_RS13275 2698884 2700482 + cyclic-di-GMP phosphodiesterase gene gene2652 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13275 HW43_RS13280 HW43_12915 HW43_RS13280 2700486 2702036 - membrane protein gene gene2653 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13280 HW43_RS13285 HW43_25260 HW43_RS13285 2702024 2702233 - hypothetical protein gene gene2654 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13285 HW43_RS13290 HW43_12920 HW43_RS13290 2702499 2703470 + PTS mannose EIIAB component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B subunit IIA transfers a phosphoryl group to subunit IIB%3B subunit IIB transfers the phosphoryl group to the substrate gene gene2655 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13290 HW43_RS13295 HW43_12925 HW43_RS13295 2703533 2704333 + mannose permease IIC component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site gene gene2656 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13295 HW43_RS13300 HW43_12930 HW43_RS13300 2704346 2705197 + PTS mannose transporter subunit IID hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IID with IIC forms the translocation channel gene gene2657 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13300 HW43_RS13305 HW43_12935 HW43_RS13305 2705252 2705710 + membrane protein gene gene2658 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13305 HW43_RS13310 HW43_25265 HW43_RS13310 2705897 2706142 + hypothetical protein gene gene2659 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13310 HW43_RS13315 HW43_12940 HW43_RS13315 2706139 2706705 + manganese efflux pump MntP membrane protein YebN gene gene2660 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13315 HW43_RS13320 HW43_12945 rrmA rrmA 2706702 2707511 - 23S rRNA methyltransferase methylates the guanosine in position 745 of 23S rRNA%3B required for translation and cell growth gene gene2661 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13320 HW43_RS13325 HW43_12950 HW43_RS13325 2707677 2707886 - cold-shock protein CspC gene gene2662 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13325 HW43_RS13330 HW43_25270 HW43_RS13330 2707899 2708042 - DUF2527 domain-containing protein gene gene2663 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13330 HW43_RS13335 HW43_25275 HW43_RS13335 2708004 2708210 + hypothetical protein gene gene2664 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13335 HW43_RS13340 HW43_12955 HW43_RS13340 2708712 2708999 - hypothetical protein gene gene2665 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13340 HW43_RS13345 HW43_12960 HW43_RS13345 2709074 2709217 - PhoP family transcriptional regulator gene gene2666 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13345 HW43_RS13350 HW43_12965 HW43_RS13350 2709376 2709615 + hypothetical protein gene gene2667 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13350 HW43_RS13355 HW43_12970 HW43_RS13355 2709758 2710549 - transcriptional regulator regulates the genes involved in 2-keto-3-deoxy gluconate transport and catabolism gene gene2668 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13355 HW43_RS13360 HW43_12975 HW43_RS13360 2710726 2712099 + transporter gene gene2669 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13360 HW43_RS13365 HW43_12980 HW43_RS13365 2712145 2713026 - protease HtpX metalloprotease gene gene2670 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13365 HW43_RS13370 HW43_12985 HW43_RS13370 2713218 2715266 - carboxyl-terminal processing protease Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 gene gene2671 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13370 HW43_RS13375 HW43_12990 HW43_RS13375 2715286 2715984 - RNA chaperone ProQ affects solute and DNA transport through an unknown mechanism gene gene2672 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13375 HW43_RS13380 HW43_12995 HW43_RS13380 2716081 2716578 - hypothetical protein gene gene2673 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13380 HW43_RS13385 HW43_13000 HW43_RS13385 2716708 2717991 + membrane protein gene gene2674 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13385 HW43_RS13390 HW43_13005 HW43_RS13390 2717960 2720593 + hypothetical protein gene gene2675 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13390 HW43_RS13395 HW43_13010 yebU yebU 2720673 2722112 + ribosomal RNA small subunit methyltransferase F in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA gene gene2676 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13395 HW43_RS13400 HW43_13015 HW43_RS13400 2722230 2722466 + hypothetical protein gene gene2677 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13400 HW43_RS13405 HW43_13020 HW43_RS13405 2722571 2722762 + hypothetical protein gene gene2678 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13405 HW43_RS13410 HW43_13025 HW43_RS13410 2722763 2723419 - serine/threonine protein phosphatase gene gene2679 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13410 HW43_RS13415 HW43_25280 HW43_RS13415 2723644 2723730 - hypothetical protein gene gene2680 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13415 HW43_RS13420 HW43_13030 HW43_RS13420 2723815 2724153 - hypothetical protein gene gene2681 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13420 HW43_RS13425 HW43_13035 HW43_RS13425 2724169 2725041 - copper resistance protein D gene gene2682 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13425 HW43_RS13430 HW43_13040 HW43_RS13430 2725045 2725419 - hypothetical protein gene gene2683 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13430 HW43_RS13435 HW43_13045 HW43_RS13435 2725558 2725788 + DNA polymerase III subunit theta gene gene2684 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13435 HW43_RS13440 HW43_25285 HW43_RS13440 2725890 2726546 + hypothetical protein gene gene2685 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13440 HW43_RS13445 HW43_13055 HW43_RS13445 2726570 2727232 + exodeoxyribonuclease X 3'-5' exonuclease activity on single or double-strand DNA gene gene2686 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13445 HW43_RS13450 HW43_13060 HW43_RS13450 2727229 2729289 - protease PtrB%3B oligopeptidase that cleaves peptide bonds following arginine and lysine residues gene gene2687 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13450 HW43_RS13455 HW43_13065 HW43_RS13455 2729498 2730157 - hypothetical protein gene gene2688 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13455 HW43_RS13460 HW43_25290 HW43_RS13460 2730217 2730327 + hypothetical protein gene gene2689 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13460 HW43_RS13465 HW43_13070 HW43_RS13465 2730484 2730840 - hypothetical protein secreted protein%3B unknown function gene gene2690 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13465 HW43_RS13470 HW43_13075 HW43_RS13470 2730907 2731197 - DNA damage-inducible protein gene gene2691 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13470 HW43_RS13475 HW43_13080 HW43_RS13475 2731331 2732509 + phosphoribosylglycinamide formyltransferase gene gene2692 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13475 HW43_RS13480 HW43_13085 HW43_RS13480 2732565 2733206 - ketohydroxyglutarate aldolase catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate%3B or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate gene gene2693 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13480 HW43_RS13485 HW43_13090 HW43_RS13485 2733243 2735054 - phosphogluconate dehydratase catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate gene gene2694 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13485 HW43_RS13490 HW43_13095 HW43_RS13490 2735289 2736764 - glucose-6-phosphate 1-dehydrogenase catalyzes the formation of D-glucono-1%2C5-lactone 6-phosphate from D-glucose 6-phosphate gene gene2695 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13490 HW43_RS13495 HW43_25295 HW43_RS13495 2736930 2737079 - hypothetical protein gene gene2696 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13495 HW43_RS13500 HW43_13100 HW43_RS13500 2737102 2737971 + transcriptional regulator Represses the expression of the zwf%2C eda%2C glp and gap gene gene2697 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13500 HW43_RS13505 HW43_13105 HW43_RS13505 2738099 2739541 + pyruvate kinase catalyzes the formation of phosphoenolpyruvate from pyruvate gene gene2698 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13505 HW43_RS13510 HW43_13110 HW43_RS13510 2739601 2740395 - hypothetical protein gene gene2699 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13510 HW43_RS13515 HW43_13120 HW43_RS13515 2740465 2741304 - esterase gene gene2700 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13515 HW43_RS13520 HW43_13125 HW43_RS13520 2741397 2742194 - hypothetical protein gene gene2701 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13520 HW43_RS13525 HW43_13130 HW43_RS13525 2742216 2744015 - cyclomaltodextrinase gene gene2702 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13525 HW43_RS13530 HW43_13135 HW43_RS13530 2744033 2744866 - maltose ABC transporter permease gene gene2703 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13530 HW43_RS13535 HW43_13140 HW43_RS13535 2744869 2746161 - sugar ABC transporter permease gene gene2704 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13535 HW43_RS13540 HW43_13145 HW43_RS13540 2746161 2747393 - sugar ABC transporter substrate-binding protein gene gene2705 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13540 HW43_RS13545 HW43_13150 HW43_RS13545 2747666 2748703 + porin gene gene2706 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13545 HW43_RS13550 HW43_13155 HW43_RS13550 2748722 2749678 + UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase gene gene2707 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13550 HW43_RS13555 HW43_13160 HW43_RS13555 2749769 2750257 + glycosidase gene gene2708 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13555 HW43_RS13560 HW43_13165 HW43_RS13560 2750340 2751467 + sugar ABC transporter ATP-binding protein gene gene2709 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13560 HW43_RS13565 HW43_13170 HW43_RS13565 2751874 2752683 + TrmB family transcriptional regulator gene gene2710 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13565 HW43_RS13570 HW43_13175 HW43_RS13570 2752772 2754640 + glycosyhydrolase gene gene2711 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13570 HW43_RS13575 HW43_13180 HW43_RS13575 2754677 2757751 + hypothetical protein gene gene2712 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13575 HW43_RS13580 HW43_13185 HW43_RS13580 2757840 2758811 - lipid A biosynthesis myristoyltransferase Transfers myristate or laurate%2C activated on ACP%2C to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA gene gene2713 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13580 HW43_RS13585 HW43_13190 HW43_RS13585 2758931 2760253 - murein DD-endopeptidase MepM gene gene2714 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13585 HW43_RS13590 HW43_13195 znuA znuA 2760269 2761216 - zinc ABC transporter substrate-binding protein involved in transport of zinc(II) with ZnuA and C gene gene2715 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13590 HW43_RS13595 HW43_13200 znuC znuC 2761280 2762035 + Mn2+/Zn2+ABC transporter ATP-binding protein involved in transport of zinc(II) with ZnuA and C gene gene2716 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13595 HW43_RS13600 HW43_13205 znuB znuB 2762032 2762817 + zinc transporter involved in transport of zinc(II) with ZnuA and C gene gene2717 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13600 HW43_RS13605 HW43_13210 HW43_RS13605 2762964 2763974 - Holliday junction DNA helicase RuvB gene gene2718 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13605 HW43_RS13610 HW43_13215 ruvA ruvA 2763983 2764594 - Holliday junction DNA helicase RuvA plays an essential role in ATP-dependent branch migration of the Holliday junction gene gene2719 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13610 HW43_RS13615 HW43_13220 HW43_RS13615 2764869 2765471 + hypothetical protein gene gene2720 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13615 HW43_RS13620 HW43_13225 ruvC ruvC 2765473 2765994 - crossover junction endodeoxyribonuclease RuvC endonuclease%3B resolves Holliday structures%3B forms a complex of RuvABC%3B the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration%3B RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity gene gene2721 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13620 HW43_RS13625 HW43_13230 HW43_RS13625 2766029 2766769 - transcriptional regulator gene gene2722 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13625 HW43_RS13630 HW43_13235 nudB nudB 2766798 2767280 - dihydroneopterin triphosphate pyrophosphatase catalyzes the formation of dihydroneopterin phosphate from dihydroneopterin triphosphate gene gene2723 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13630 HW43_RS13635 HW43_13240 HW43_RS13635 2767368 2769140 - aspartate--tRNA ligase gene gene2724 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13635 HW43_RS13640 HW43_13245 HW43_RS13640 2769450 2770016 + hydrolase gene gene2725 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13640 HW43_RS13645 HW43_13250 HW43_RS13645 2770013 2770831 + hypothetical protein gene gene2726 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13645 HW43_RS13650 HW43_13255 HW43_RS13650 2770884 2771279 + hypothetical protein gene gene2727 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13650 HW43_RS13655 HW43_13260 HW43_RS13655 2771320 2772063 + tRNA (cmo5U34)-methyltransferase catalyzes the conversion of 5-methoxyuridine to uridine-5-oxyacetic acid in tRNA gene gene2728 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13655 HW43_RS13660 HW43_13265 HW43_RS13660 2772060 2773031 + tRNA (mo5U34)-methyltransferase catalyzes the conversion of 5-hydroxyuridine to 5-methoxyuridine in tRNA gene gene2729 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13660 HW43_RS13665 HW43_13270 HW43_RS13665 2773196 2775625 - biotin sulfoxide reductase catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine gene gene2730 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13665 HW43_RS13670 HW43_13275 HW43_RS13670 2775650 2776750 - cytochrome C gene gene2731 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13670 HW43_RS13675 HW43_13280 HW43_RS13675 2777138 2777884 - copper homeostasis protein CutC gene gene2732 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13675 HW43_RS13680 HW43_13285 HW43_RS13680 2777898 2778464 - hypothetical protein gene gene2733 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13680 HW43_RS13685 HW43_13290 HW43_RS13685 2778680 2780413 + arginine--tRNA ligase gene gene2734 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13685 HW43_RS13690 HW43_13295 HW43_RS13690 2780590 2781078 + hypothetical protein gene gene2735 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13690 HW43_RS13695 HW43_13300 HW43_RS13695 2781198 2781590 - flagellar biosynthesis protein FlhE gene gene2736 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13695 HW43_RS13700 HW43_13305 HW43_RS13700 2781590 2783668 - flagellar biosynthesis protein FlhA gene gene2737 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13700 HW43_RS13705 HW43_13310 flhB flhB 2783661 2784809 - flagellar biosynthetic protein FlhB membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export gene gene2738 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13705 HW43_RS13710 HW43_13315 HW43_RS13710 2785011 2785655 - protein phosphatase CheZ cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation gene gene2739 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13710 HW43_RS13715 HW43_13320 HW43_RS13715 2785666 2786055 - chemotaxis protein CheY chemotaxis regulator that%2C when phosphorylated%2C interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble gene gene2740 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13715 HW43_RS13720 HW43_13325 HW43_RS13720 2786070 2787119 - two-component system protein-glutamate methylesterase response regulator regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins gene gene2741 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13720 HW43_RS13725 HW43_13330 HW43_RS13725 2787122 2787982 - chemotaxis protein CheR methylates the MCP gene gene2742 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13725 HW43_RS13730 HW43_13335 HW43_RS13730 2788001 2789602 - methyl-accepting chemotaxis protein mediates taxis toward dipeptides gene gene2743 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13730 HW43_RS13735 HW43_13340 HW43_RS13735 2789648 2791309 - methyl-accepting chemotaxis protein serine sensor receptor gene gene2744 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13735 HW43_RS13740 HW43_13345 HW43_RS13740 2791454 2791957 - chemotaxis protein CheW gene gene2745 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13740 HW43_RS13745 HW43_13350 HW43_RS13745 2791978 2793936 - chemotaxis protein CheA gene gene2746 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13745 HW43_RS13750 HW43_13355 motB motB 2793947 2794873 - motility protein B with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine gene gene2747 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13750 HW43_RS13755 HW43_13360 HW43_RS13755 2794870 2795757 - motility protein A With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine gene gene2748 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13755 HW43_RS13760 HW43_13365 HW43_RS13760 2795884 2796462 - flagellar transcriptional regulator FlhC With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems gene gene2749 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13760 HW43_RS13765 HW43_13370 HW43_RS13765 2796465 2796815 - flagellar transcriptional regulator FlhD with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems gene gene2750 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13765 HW43_RS13770 HW43_13375 HW43_RS13770 2797595 2798023 + universal stress protein C ppGpp-dependent%3B membrane-associated%2C stress protein produced under conditions of nutrient deprivation%2C osmotic shock and oxidative stress gene gene2751 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13770 HW43_RS13775 HW43_13380 HW43_RS13775 2798030 2799454 - alpha%2Calpha-trehalose-phosphate synthase [UDP-forming] gene gene2752 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13775 HW43_RS13780 HW43_13385 HW43_RS13780 2799429 2800229 - trehalose-6-phosphate phosphatase biosynthetic%3B catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate%3B expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature gene gene2753 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13780 HW43_RS13785 HW43_13390 araH araH 2800396 2801382 - arabinose ABC transporter permease Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose gene gene2754 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13785 HW43_RS13790 HW43_13395 araG araG 2801397 2802911 - arabinose import ATP-binding protein AraG Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose gene gene2755 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13790 HW43_RS13795 HW43_13400 HW43_RS13795 2802981 2803970 - L-arabinose-binding periplasmic protein with AraGH is involved in the transport of arabinose into the cell gene gene2756 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13795 HW43_RS13800 HW43_13405 HW43_RS13800 2804767 2805270 + non-heme ferritin ferritin B%3B required for virulence in Salmonella%3B may be involved in repair of damaged Fe-S clusters gene gene2757 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13800 HW43_RS13805 HW43_13410 HW43_RS13805 2805349 2805600 - hypothetical protein gene gene2758 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13805 HW43_RS13810 HW43_25300 HW43_RS13810 2805712 2805858 + hypothetical protein gene gene2759 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13810 HW43_RS13815 HW43_13415 HW43_RS13815 2805895 2806089 - hypothetical protein gene gene2760 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13815 HW43_RS13820 HW43_25305 HW43_RS13820 2806062 2806385 + lipoprotein%2C function unknown gene gene2761 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13820 HW43_RS13825 HW43_13425 HW43_RS13825 2806556 2807053 + non-heme ferritin cytoplasmic iron storage protein gene gene2762 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13825 HW43_RS13830 HW43_13430 HW43_RS13830 2807091 2807330 - DUF2492 domain-containing protein gene gene2763 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13830 HW43_RS13835 HW43_13435 HW43_RS13835 2807521 2808732 + tyrosine-specific transporter tyrosine specific permease gene gene2764 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13835 HW43_RS13840 HW43_13440 HW43_RS13840 2808794 2809459 - hypothetical protein gene gene2765 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13840 HW43_RS13845 HW43_13445 HW43_RS13845 2809655 2809741 - tRNA-Leu tRNA gene2766 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13845 HW43_RS13850 HW43_13450 HW43_RS13850 2809754 2809827 - tRNA-Cys tRNA gene2767 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13850 HW43_RS13855 HW43_13455 HW43_RS13855 2809882 2809957 - tRNA-Gly tRNA gene2768 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13855 HW43_RS13860 HW43_13460 HW43_RS13860 2810109 2810657 - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase gene gene2769 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13860 HW43_RS13865 HW43_13465 uvrC uvrC 2810714 2812546 - UvrABC system protein C The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision gene gene2770 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13865 HW43_RS13870 HW43_13470 sirA sirA 2812543 2813199 - transcriptional regulator in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system%3B in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system gene gene2771 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13870 HW43_RS13875 HW43_25310 HW43_RS13875 2813495 2813671 + 2-oxo acid dehydrogenase gene gene2772 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13875 HW43_RS13880 HW43_13475 HW43_RS13880 2813658 2813882 + hypothetical protein gene gene2773 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13880 HW43_RS13885 HW43_13480 HW43_RS13885 2813949 2814671 - transcriptional regulator regulates genes involved in cell division gene gene2774 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13885 HW43_RS13890 HW43_13485 HW43_RS13890 2814901 2815653 - amino acid ABC transporter ATP-binding protein gene gene2775 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13890 HW43_RS13895 HW43_13490 HW43_RS13895 2815650 2816318 - amino acid ABC transporter permease gene gene2776 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13895 HW43_RS13900 HW43_13495 HW43_RS13900 2816333 2817319 - D-cysteine desulfhydrase catalyzes the formation of pyruvate from D-cysteine gene gene2777 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13900 HW43_RS13905 HW43_13500 HW43_RS13905 2817424 2818224 - cystine transporter subunit gene gene2778 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13905 HW43_RS13910 HW43_13505 HW43_RS13910 2818312 2818863 - flagellar biosynthesis protein FliZ expression activator of the class 2 type of flagellar operons%2C essential to achieve maximal cell motility%3B activator of type 1 fimbrial gene expression%3B cell density-responsive regulator%3B FliZ in Salmonella typhimurium induces HilA%2C an activator of invasion genes necessary to achieve full virulence gene gene2779 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13910 HW43_RS13915 HW43_13510 fliA fliA 2818909 2819628 - RNA polymerase sigma factor FliA sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B this sigma factor directs late flagellar biosynthesis genes gene gene2780 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13915 HW43_RS13920 HW43_13515 HW43_RS13920 2819793 2821268 - flagellin gene gene2781 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13920 HW43_RS13925 HW43_13520 HW43_RS13925 2821523 2822935 + flagellar capping protein gene gene2782 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13925 HW43_RS13930 HW43_13525 fliS fliS 2822950 2823360 + flagellar export chaperone FliS flagellin specific chaperone gene gene2783 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13930 HW43_RS13935 HW43_13530 HW43_RS13935 2823360 2823725 + flagellar protein FliT binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway%3B acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription%3B member of the type III cytoplasmic chaperone family gene gene2784 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13935 HW43_RS13940 HW43_13535 HW43_RS13940 2823803 2825290 + alpha-amylase converts 1%2C4-alpha-D-glucans to maltodextrin gene gene2785 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13940 HW43_RS13945 HW43_13540 HW43_RS13945 2825324 2825737 - lipoprotein gene gene2786 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13945 HW43_RS13950 HW43_13545 HW43_RS13950 2825924 2827129 + hypothetical protein gene gene2787 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13950 HW43_RS13955 HW43_13550 HW43_RS13955 2827126 2827359 + TusA family sulfurtransferase gene gene2788 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13955 HW43_RS13960 HW43_13555 HW43_RS13960 2827466 2828134 + hypothetical protein gene gene2789 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13960 HW43_RS13965 HW43_25315 HW43_RS13965 2828355 2828607 + integrase gene gene2790 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13965 HW43_RS13970 HW43_13560 fliE fliE 2828527 2828841 - flagellar hook-basal body complex protein FliE forms a junction between the M-ring and FlgB during flagella biosynthesis gene gene2791 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13970 HW43_RS13975 HW43_13565 fliF fliF 2829056 2830714 + flagellar MS-ring protein the MS-ring anchors the flagellum to the cytoplasmic membrane%3B part of the flagellar basal body which consists of four rings L%2C P%2C S%2C and M mounted on a central rod gene gene2792 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13975 HW43_RS13980 HW43_13570 fliG fliG 2830707 2831702 + flagellar motor switch protein FliG One of three proteins involved in switching the direction of the flagellar rotation gene gene2793 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13980 HW43_RS13985 HW43_13575 fliH fliH 2831695 2832381 + flagellar assembly protein FliH binds to and inhibits the function of flagella specific ATPase FliI gene gene2794 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13985 HW43_RS13990 HW43_13580 fliI fliI 2832381 2833754 + flagellum-specific ATP synthase involved in type III protein export during flagellum assembly gene gene2795 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13990 HW43_RS13995 HW43_13585 fliJ fliJ 2833773 2834216 + flagellar biosynthesis chaperone rod/hook and filament chaperone gene gene2796 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS13995 HW43_RS14000 HW43_13590 HW43_RS14000 2834213 2835340 + flagellar hook-length control protein FliK gene gene2797 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14000 HW43_RS14005 HW43_13595 fliL fliL 2835445 2835909 + flagellar basal body protein FliL interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring gene gene2798 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14005 HW43_RS14010 HW43_13600 fliM fliM 2835914 2836918 + flagellar motor switch protein FliM with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation gene gene2799 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14010 HW43_RS14015 HW43_13605 fliN fliN 2836915 2837328 + flagellar motor switch protein FliN One of three proteins involved in switching the direction of the flagellar rotation gene gene2800 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14015 HW43_RS14020 HW43_13610 HW43_RS14020 2837331 2837696 + flagellar protein FliO with FlhA%2C FlhB%2C FliP%2C FliQ and FliR is one of the membrane components of the flagellar export apparatus gene gene2801 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14020 HW43_RS14025 HW43_13615 fliP fliP 2837696 2838433 + flagellar biosynthetic protein FliP FliP%2C with proteins FliQ and FliR%2C forms the core of the central channel in the flagella export apparatus gene gene2802 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14025 HW43_RS14030 HW43_13620 fliQ fliQ 2838443 2838712 + flagellar biosynthetic protein FliQ with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus gene gene2803 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14030 HW43_RS14035 HW43_13625 fliR fliR 2838721 2839506 + flagellar biosynthesis protein FliR FliR%2C with proteins FliP and FliQ%2C forms the core of the central channel in the flagella export apparatus gene gene2804 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14035 HW43_RS14040 HW43_13630 rcsA rcsA 2839796 2840419 + transcriptional regulator with RcsB is a positive regulator of capsular polysaccharide synthesis genes gene gene2805 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14040 HW43_RS14045 HW43_13635 HW43_RS14045 2840463 2840651 - protein DsrB gene gene2806 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14045 HW43_RS14050 HW43_13640 HW43_RS14050 2840814 2841041 + hypothetical protein gene gene2807 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14050 HW43_RS14055 HW43_13645 HW43_RS14055 2841339 2842154 + mannosyl-3-phosphoglycerate phosphatase catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate gene gene2808 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14055 HW43_RS14060 HW43_13650 HW43_RS14060 2842151 2843827 - diguanylate cyclase catalyzes the formation of cyclic di-3'%2C5'-guanylate from guanosine triphosphate%3B involved in the regulation of cellulose biosynthesis gene gene2809 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14060 HW43_RS14065 HW43_13655 HW43_RS14065 2844016 2844198 - hypothetical protein gene gene2810 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14065 HW43_RS14070 HW43_13660 HW43_RS14070 2844277 2845194 - membrane protein gene gene2811 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14070 HW43_RS14075 HW43_13665 HW43_RS14075 2845367 2846287 + amino acid exporter for phenylalanine%2C threonine gene gene2812 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14075 HW43_RS14080 HW43_13670 HW43_RS14080 2846276 2846746 - very short patch repair protein DNA mismatch endonuclease%3B recognizes and repairs T:G mismatches gene gene2813 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14080 HW43_RS14085 HW43_13675 HW43_RS14085 2846727 2848145 - DNA-cytosine methyltransferase gene gene2814 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14085 HW43_RS14090 HW43_13680 HW43_RS14090 2848212 2848907 - hydrolase gene gene2815 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14090 HW43_RS14095 HW43_13685 HW43_RS14095 2848947 2849249 - permease gene gene2816 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14095 HW43_RS14105 HW43_13695 HW43_RS14105 2849879 2850937 + outer membrane protein F gene gene2817 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14105 HW43_RS14110 HW43_25320 HW43_RS14110 2851051 2851276 + hypothetical protein gene gene2818 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14110 HW43_RS14115 HW43_13705 HW43_RS14115 2851529 2852380 + Molecular chaperone Hsp31 and glyoxalase 3 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress gene gene2819 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14115 HW43_RS14120 HW43_13710 HW43_RS14120 2852487 2853845 - two-component system sensor histidine kinase gene gene2820 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14120 HW43_RS14125 HW43_13715 HW43_RS14125 2853845 2854516 - two-component system response regulator induced by CusR in the presence of copper%3B YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW%3B yedVW is one of four copper regulons found in E. coli%3B part of the copper homeostasis mechanism%3B confers resistance to copper and several drugs when induced gene gene2821 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14125 HW43_RS14130 HW43_13720 HW43_RS14130 2854649 2855062 + 5-hydroxyisourate hydrolase catalyzes the formation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline from 5-hydroxyisourate gene gene2822 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14130 HW43_RS14135 HW43_13725 HW43_RS14135 2855171 2856175 + sulfoxide reductase catalytic subunit YedY in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase%3B requires inner membrane anchor protein YedZ gene gene2823 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14135 HW43_RS14140 HW43_13730 HW43_RS14140 2856176 2856811 + sulfoxide reductase heme-binding subunit YedZ in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY%3B sulfite oxidase activity not demonstrated%3B contains heme gene gene2824 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14140 HW43_RS14145 HW43_13735 HW43_RS14145 2857068 2857718 + zinc/cadmium-binding protein gene gene2825 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14145 HW43_RS14150 HW43_13740 HW43_RS14150 2858061 2858591 + cytochrome b561 homolog 1 gene gene2826 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14150 HW43_RS14155 HW43_25325 HW43_RS14155 2858614 2858856 + hypothetical protein gene gene2827 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14155 HW43_RS14160 HW43_13745 HW43_RS14160 2859160 2859249 - tRNA-Ser tRNA gene2828 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14160 HW43_RS14165 HW43_13750 HW43_RS14165 2859343 2860140 + protein MtfA Mlc anti-repressor%3B regulates ptsG by binding and inactivating Mlc gene gene2829 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14165 HW43_RS14170 HW43_13755 HW43_RS14170 2860241 2860316 + tRNA-Asn tRNA gene2830 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14170 HW43_RS14185 HW43_RS14185 HW43_RS14185 2864959 2865100 + adhesin gene gene2834 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14185 HW43_RS14190 HW43_RS14190 HW43_RS14190 2865136 2867706 + cell motility protein gene gene2835 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14190 HW43_RS14195 HW43_13765 HW43_RS14195 2867968 2869020 - hypothetical protein gene gene2836 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14195 HW43_RS14200 HW43_13770 HW43_RS14200 2869335 2870651 + shikimate transporter gene gene2837 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14200 HW43_RS14205 HW43_13775 HW43_RS14205 2870753 2872207 + AMP nucleosidase Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile gene gene2838 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14205 HW43_RS14210 HW43_13780 HW43_RS14210 2872550 2873266 + transcriptional regulator gene gene2839 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14210 HW43_RS14215 HW43_13785 HW43_RS14215 2873718 2873793 - tRNA-Asn tRNA gene2840 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14215 HW43_RS14220 HW43_13790 HW43_RS14220 2873894 2875348 - MATE family multidrug exporter gene gene2841 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14220 HW43_RS14225 HW43_13795 HW43_RS14225 2875542 2875617 + tRNA-Asn tRNA gene2842 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14225 HW43_RS14230 HW43_13800 HW43_RS14230 2875779 2877053 + integrase gene gene2843 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14230 HW43_RS14235 HW43_13805 HW43_RS14235 2877865 2879127 + integrase gene gene2844 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14235 HW43_RS14240 HW43_13810 HW43_RS14240 2879590 2883183 + hypothetical protein gene gene2845 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14240 HW43_RS14245 HW43_13815 HW43_RS14245 2883256 2886984 + hypothetical protein gene gene2846 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14245 HW43_RS14250 HW43_13820 HW43_RS14250 2887404 2888330 - HNH endonuclease gene gene2847 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14250 HW43_RS14255 HW43_13825 HW43_RS14255 2888327 2890618 - hypothetical protein gene gene2848 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14255 HW43_RS14260 HW43_13830 cbl cbl 2891042 2891992 - CysB family transcriptional regulator LysR-type transcriptional regulator similar to CysB%3B contains helix-turn-helix (HTH) motif%3B in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon%3B regulated by CysB%3B DNA-binding transcriptional activator for the ssuEADCB and tauABCD operons gene gene2849 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14260 HW43_RS14265 HW43_13835 HW43_RS14265 2892094 2893011 - nitrogen assimilation regulatory protein nac Transcriptional activator for the hut%2C put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation gene gene2850 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14265 HW43_RS14270 HW43_13840 HW43_RS14270 2893338 2893413 + tRNA-Asn tRNA gene2851 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14270 HW43_RS14275 HW43_13845 HW43_RS14275 2893469 2894401 - transpeptidase catalyzes th removal of D-alanine and attachment of the murein lipoprotein to the peptidoglycan tetrapeptide chain gene gene2852 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14275 HW43_RS14280 HW43_13850 cobT cobT 2894466 2895545 - nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5%2C6-dimethylbenzimidazole gene gene2853 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14280 HW43_RS14285 HW43_13855 cobS cobS 2895557 2896300 - adenosylcobinamide-GDP ribazoletransferase catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole gene gene2854 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14285 HW43_RS14290 HW43_13860 cobU cobU 2896297 2896830 - adenosylcobinamide kinase catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP gene gene2855 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14290 HW43_RS14295 HW43_13865 HW43_RS14295 2896964 2897401 - cobalamin biosynthesis protein gene gene2856 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14295 HW43_RS14300 HW43_13870 HW43_RS14300 2897883 2898797 - hypothetical protein gene gene2857 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14300 HW43_RS14305 HW43_13875 HW43_RS14305 2899000 2899809 - glycerol uptake facilitator GlpF involved in the transport of glycerol into the cell gene gene2858 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14305 HW43_RS14310 HW43_13880 HW43_RS14310 2900321 2900605 + carboxysome shell protein ethanolamine utilization protein%3B involved in the degredation of ethanolamine gene gene2859 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14310 HW43_RS14315 HW43_13885 HW43_RS14315 2900602 2901414 + propanediol utilization protein PduB carboxysome shell protein%3B may be involved in the formation of the polyhedral organelles involved in propanediol degradation gene gene2860 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14315 HW43_RS14320 HW43_13890 pduC pduC 2901433 2903097 + propanediol dehydratase large subunit with pduED catalyzes the formation of propionaldehyde from 1%2C2-propanediol gene gene2861 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14320 HW43_RS14325 HW43_13895 pduD pduD 2903107 2903775 + propanediol dehydratase medium subunit with PduCE catalyzes the formation of propionaldehyde from 1%2C2-propanediol gene gene2862 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14325 HW43_RS14330 HW43_13900 pduE pduE 2903790 2904308 + propanediol dehydratase small subunit with pduCD catalyzes the formation of propionaldehyde from 1%2C2-propanediol gene gene2863 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14330 HW43_RS14335 HW43_13905 HW43_RS14335 2904318 2906150 + diol dehydratase reactivase subunit alpha gene gene2864 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14335 HW43_RS14340 HW43_13910 HW43_RS14340 2906140 2906490 + propanediol dehydratase gene gene2865 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14340 HW43_RS14345 HW43_13915 HW43_RS14345 2906510 2906785 + carboxysome shell protein ethanolamine utilization protein%3B involved in the degredation of ethanolamine gene gene2866 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14345 HW43_RS14350 HW43_13920 HW43_RS14350 2906809 2907231 + microcompartments protein gene gene2867 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14350 HW43_RS14355 HW43_13925 HW43_RS14355 2907234 2907866 + propanediol utilization phosphotransacylase catalyzes the formation of propionyl phosphate from propionyl-CoA in propanediol degradation gene gene2868 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14355 HW43_RS14360 HW43_13930 HW43_RS14360 2907863 2908354 + microcompartment protein PduM gene gene2869 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14360 HW43_RS14365 HW43_13935 HW43_RS14365 2908358 2908633 + ethanolamine utilization protein EutN gene gene2870 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14365 HW43_RS14370 HW43_13940 HW43_RS14370 2908645 2909652 + propanediol utilization protein gene gene2871 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14370 HW43_RS14375 HW43_13945 HW43_RS14375 2909649 2911034 + aldehyde dehydrogenase gene gene2872 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14375 HW43_RS14380 HW43_13950 HW43_RS14380 2911045 2912157 + hypothetical protein gene gene2873 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14380 HW43_RS14385 HW43_13955 HW43_RS14385 2912154 2913497 + hypothetical protein gene gene2874 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14385 HW43_RS14390 HW43_13960 HW43_RS14390 2913500 2914054 + propanediol utilization: polyhedral bodies pduT gene gene2875 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14390 HW43_RS14395 HW43_13965 HW43_RS14395 2914054 2914404 + propanediol utilization protein PduU gene gene2876 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14395 HW43_RS14400 HW43_13970 HW43_RS14400 2914409 2914852 + propanediol utilization protein pduV gene gene2877 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14400 HW43_RS14405 HW43_13975 HW43_RS14405 2914953 2915282 - hypothetical protein gene gene2878 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14405 HW43_RS14410 HW43_13980 HW43_RS14410 2915454 2916512 - hypothetical protein gene gene2879 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14410 HW43_RS14415 HW43_13985 HW43_RS14415 2916711 2917184 - DNA gyrase inhibitor gene gene2880 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14415 HW43_RS14420 HW43_13990 HW43_RS14420 2917303 2918469 - D-alanyl-D-alanine carboxypeptidase removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors%3B penicillin-binding protein 6B%3B one of four%2C DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains gene gene2881 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14420 HW43_RS14425 HW43_13995 sbcB sbcB 2918681 2920105 + exonuclease I Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates gene gene2882 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14425 HW43_RS14430 HW43_14000 HW43_RS14430 2920148 2920375 - membrane protein gene gene2883 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14430 HW43_RS14435 HW43_14005 HW43_RS14435 2920389 2921447 - membrane protein gene gene2884 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14435 HW43_RS14440 HW43_14010 HW43_RS14440 2921626 2922984 - low-affinity putrescine importer PlaP gene gene2885 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14440 HW43_RS14445 HW43_14015 HW43_RS14445 2923251 2924180 - LysR family transcriptional regulator gene gene2886 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14445 HW43_RS14450 HW43_14020 HW43_RS14450 2924226 2925050 - hypothetical protein gene gene2887 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14450 HW43_RS14455 HW43_14025 HW43_RS14455 2925133 2925387 - toxin YoeB gene gene2888 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14455 HW43_RS14460 HW43_14030 HW43_RS14460 2925384 2925635 - antitoxin YefM Antitoxin that counteracts the effect of the YoeB toxin gene gene2889 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14460 HW43_RS14465 HW43_14035 hisG hisG 2926114 2927013 + ATP phosphoribosyltransferase long form of enzyme%3B catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate%3B crucial role in histidine biosynthesis%3B forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors gene gene2890 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14465 HW43_RS14470 HW43_14040 hisD hisD 2927019 2928323 + bifunctional histidinal dehydrogenase/ histidinol dehydrogenase catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis%3B functions as a dimer gene gene2891 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14470 HW43_RS14475 HW43_14045 HW43_RS14475 2928320 2929390 + histidinol-phosphate aminotransferase catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis gene gene2892 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14475 HW43_RS14480 HW43_14050 HW43_RS14480 2929390 2930457 + histidine biosynthesis bifunctional protein HisB catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate gene gene2893 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14480 HW43_RS14485 HW43_14055 hisH hisH 2930457 2931047 + imidazole glycerol phosphate synthase subunit HisH with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate%2C 5-aminoimidazol-4-carboxamide ribonucleotide%2C and glutamate in histidine biosynthesis%3B the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide gene gene2894 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14485 HW43_RS14490 HW43_14060 HW43_RS14490 2931047 2931784 + 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase gene gene2895 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14490 HW43_RS14495 HW43_14065 HW43_RS14495 2931766 2932542 + imidazole glycerol phosphate synthase subunit HisF gene gene2896 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14495 HW43_RS14500 HW43_14070 HW43_RS14500 2932536 2933147 + histidine biosynthesis HisIE catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis gene gene2897 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14500 HW43_RS14505 HW43_14075 HW43_RS14505 2933244 2934221 - chain length determinant protein regulator of length of O-antigen component of lipopolysaccharide chains gene gene2898 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14505 HW43_RS14510 HW43_14080 HW43_RS14510 2934368 2935534 - UDP-glucose 6-dehydrogenase catalyzes the formation of UDP-glucuronate from UDP-glucose gene gene2899 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14510 HW43_RS14515 HW43_14085 HW43_RS14515 2935782 2937188 - 6-phosphogluconate dehydrogenase catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate gene gene2900 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14515 HW43_RS14520 HW43_14090 HW43_RS14520 2937309 2938115 - amylovoran biosynthesis protein AmsE gene gene2901 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14520 HW43_RS14525 HW43_14095 HW43_RS14525 2938140 2939417 - hypothetical protein gene gene2902 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14525 HW43_RS14530 HW43_14100 HW43_RS14530 2939417 2940640 - hypothetical protein gene gene2903 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14530 HW43_RS14535 HW43_14105 HW43_RS14535 2940646 2941758 - hypothetical protein gene gene2904 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14535 HW43_RS14540 HW43_14110 HW43_RS14540 2941755 2942705 - hypothetical protein gene gene2905 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14540 HW43_RS14545 HW43_14115 HW43_RS14545 2942790 2943953 - polyhydroxyalkanoate synthesis repressor PhaR gene gene2906 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14545 HW43_RS14550 HW43_14120 HW43_RS14550 2943950 2945215 - N-acylneuraminate cytidylyltransferase gene gene2907 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14550 HW43_RS14555 HW43_14125 HW43_RS14555 2945221 2946261 - N-acetyl neuramic acid synthetase NeuB gene gene2908 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14555 HW43_RS14560 HW43_14130 HW43_RS14560 2946266 2946886 - shikimate 5-dehydrogenase gene gene2909 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14560 HW43_RS14565 HW43_14135 HW43_RS14565 2947247 2948140 - UTP--glucose-1-phosphate uridylyltransferase gene gene2910 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14565 HW43_RS14570 HW43_14140 HW43_RS14570 2948383 2949378 - N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans%2Coctacis-undecaprenol 4-epimerase gene gene2911 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14570 HW43_RS14575 HW43_14145 wcaM wcaM 2949536 2950930 - colanic acid biosynthesis protein WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface%3B may be involved in the biosynthesis of colanic acid gene gene2912 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14575 HW43_RS14580 HW43_14150 HW43_RS14580 2950941 2952161 - colanic acid biosynthesis glycosyltransferase WcaL gene gene2913 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14580 HW43_RS14585 HW43_14155 HW43_RS14585 2952158 2953438 - colanic acid biosynthesis pyruvyl transferase WcaK gene gene2914 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14585 HW43_RS14590 HW43_14160 HW43_RS14590 2953723 2955201 - colanic acid exporter gene gene2915 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14590 HW43_RS14595 HW43_14165 HW43_RS14595 2955203 2956597 - UDP-glucose lipid carrier transferase WcaJ%3B glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid gene gene2916 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14595 HW43_RS14600 HW43_14170 HW43_RS14600 2956652 2958022 - phosphomannomutase capsular polysaccharide biosynthesis protein%3B catalyzes the formation of D-mannose 6-phosphate from alpha-D-mannose 1-phosphate gene gene2917 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14600 HW43_RS14605 HW43_14175 cpsB cpsB 2958215 2959651 - mannose-1-phosphate guanyltransferase capsular polysaccharide colanic acid biosynthesis protein%3B catalyzes the formation of GDP-mannose from GTP and alpha-D-mannose 1-phosphate gene gene2918 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14605 HW43_RS14610 HW43_14180 HW43_RS14610 2959654 2960877 - glycosyl transferase gene gene2919 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14610 HW43_RS14615 HW43_14185 HW43_RS14615 2960874 2961353 - GDP-mannose mannosyl hydrolase NudD catalyzes the formation of GDP and D-mannose from GDP-D-mannose%3B also hydrolyzes GDP-glucose gene gene2920 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14615 HW43_RS14620 HW43_14190 HW43_RS14620 2961356 2962321 - GDP-fucose synthetase bifunctional GDP-4-dehydro-6-deoxy-D-mannose epimerase/ GDP-4-dehydro-6-L-deoxygalactose reductase%3Bcatalyzes the formation of GDP-fucose from GDP-4-dehydro-6-deoxy-D-mannose gene gene2921 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14620 HW43_RS14625 HW43_14195 HW43_RS14625 2962324 2963445 - GDP-mannose 4%2C6-dehydratase catalyzes the formation of GDP-4-dehydro-6-deoxy-D-mannose from GDP mannose gene gene2922 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14625 HW43_RS14630 HW43_14200 HW43_RS14630 2963471 2964019 - colanic acid biosynthesis acetyltransferase WcaF gene gene2923 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14630 HW43_RS14635 HW43_14205 HW43_RS14635 2964035 2964781 - colanic acid biosynthesis glycosyltransferase WcaE gene gene2924 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14635 HW43_RS14640 HW43_14210 wcaD wcaD 2964792 2966009 - colanic acid biosynthesis protein essential for colanic acid biosynthesis%3B colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance gene gene2925 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14640 HW43_RS14645 HW43_14215 HW43_RS14645 2965984 2967201 - colanic acid biosynthesis glycosyltransferase WcaC gene gene2926 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14645 HW43_RS14650 HW43_14220 HW43_RS14650 2967198 2967686 - colanic acid biosynthesis acetyltransferase WcaB acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit)%3B wcaB is induced in sessile bacteria and by osmotic shock%2C and repressed when grown in rich medium gene gene2927 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14650 HW43_RS14655 HW43_14225 HW43_RS14655 2967689 2968528 - glycosyl transferase gene gene2928 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14655 HW43_RS14660 HW43_14230 HW43_RS14660 2968621 2970783 - tyrosine kinase Wzc%3B catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide) gene gene2929 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14660 HW43_RS14665 HW43_14235 HW43_RS14665 2970786 2971229 - protein-tyrosine phosphatase Wzb shows phosphatase activity towards the autophosphorylated Wzc protein%2C which induces colanic acid biosynthesis%3B catalyzes the phosphorylation of UDP-glucose dehydrogenase%2C an enzyme involved in colanic acid biosynthesis gene gene2930 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14665 HW43_RS14670 HW43_14240 HW43_RS14670 2971235 2972374 - lipoprotein required for the translocation of capsular polysaccharide through the outer membrane gene gene2931 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14670 HW43_RS14675 HW43_14245 HW43_RS14675 2973033 2974616 + membrane protein gene gene2932 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14675 HW43_RS14680 HW43_14250 HW43_RS14680 2974890 2976743 - protein AsmA YegA%3B inner membrane protein involved in the assembly of outer membrane proteins (OMPs)%3B asmA-null mutants show low lipopolysaccharide (LPS) levels%2C suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity%2C resulting on altered assembly of OMPs gene gene2933 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14680 HW43_RS14685 HW43_14255 HW43_RS14685 2976765 2977346 - deoxycytidine triphosphate deaminase gene gene2934 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14685 HW43_RS14690 HW43_14260 HW43_RS14690 2977438 2978079 - uridine kinase gene gene2935 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14690 HW43_RS14695 HW43_14265 HW43_RS14695 2978397 2981714 + diguanylate cyclase gene gene2936 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14695 HW43_RS14700 HW43_14270 HW43_RS14700 2981753 2982610 - 3-methyl-adenine DNA glycosylase inducible%2C catalyzes the hydrolysis of alkylated DNA%2C releasing 3-methyladenine%2C 3-methylguanine%2C 7-methylguanine and 7-methyladenine gene gene2937 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14700 HW43_RS14705 HW43_14275 HW43_RS14705 2982744 2984096 + chaperone gene gene2938 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14705 HW43_RS14710 HW43_14280 HW43_RS14710 2984108 2986054 - hypothetical protein gene gene2939 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14710 HW43_RS14715 HW43_14285 HW43_RS14715 2986051 2986812 - hypothetical protein gene gene2940 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14715 HW43_RS14720 HW43_14290 HW43_RS14720 2986809 2987468 - hypothetical protein gene gene2941 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14720 HW43_RS14725 HW43_14295 HW43_RS14725 2988684 2989931 + multidrug resistance protein MdtA Part of a tripartite efflux system composed of MdtA%2C MdtB and MdtC which confers resistance against novobiocin and deoxycholate gene gene2942 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14725 HW43_RS14730 HW43_14300 HW43_RS14730 2989931 2993053 + multidrug resistance protein MdtB Part of a tripartite efflux system composed of MdtA%2C MdtB and MdtC which confers resistance against novobiocin and deoxycholate gene gene2943 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14730 HW43_RS14735 HW43_14305 HW43_RS14735 2993054 2996131 + multidrug resistance protein MdtC Part of a tripartite efflux system composed of MdtA%2C MdtB and MdtC which confers resistance against novobiocin and deoxycholate gene gene2944 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14735 HW43_RS14740 HW43_14310 HW43_RS14740 2996132 2997547 + transporter gene gene2945 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14740 HW43_RS14745 HW43_14315 HW43_RS14745 2997544 2998947 + two-component system sensor histidine kinase gene gene2946 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14745 HW43_RS14750 HW43_14320 HW43_RS14750 2998944 2999666 + two-component system response regulator response regulator in two-component regulatory system with BaeS%3B regulator of RNA synthesis%2C flagellar biosynthesis%2C chemotaxis and transport gene gene2947 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14750 HW43_RS14755 HW43_14325 HW43_RS14755 2999857 3000189 + hypothetical protein gene gene2948 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14755 HW43_RS14760 HW43_14330 HW43_RS14760 3000443 3000694 + CopG family transcriptional regulator gene gene2949 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14760 HW43_RS14765 HW43_14335 HW43_RS14765 3000696 3000992 + plasmid stabilization protein ParE gene gene2950 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14765 HW43_RS14770 HW43_14340 HW43_RS14770 3001095 3002456 + protease gene gene2951 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14770 HW43_RS14775 HW43_25335 HW43_RS14775 3002649 3002798 - hypothetical protein gene gene2952 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14775 HW43_RS14780 HW43_14345 HW43_RS14780 3002786 3003118 - hypothetical protein gene gene2953 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14780 HW43_RS14785 HW43_14350 HW43_RS14785 3003518 3004417 + lipid kinase cytosolic protein with phosphatidylglycerol kinase activity%3B undetermined physiological role gene gene2954 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14785 HW43_RS14790 HW43_14355 HW43_RS14790 3004499 3005272 - galactitol utilization operon repressor gene gene2955 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14790 HW43_RS14795 HW43_14360 HW43_RS14795 3005378 3006418 - galactitol-1-phosphate 5-dehydrogenase Zn-dependent%3B NAD(P)-binding%3B catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate gene gene2956 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14795 HW43_RS14800 HW43_14365 HW43_RS14800 3006466 3007821 - PTS galactitol transporter subunit IIC gene gene2957 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14800 HW43_RS14805 HW43_14370 HW43_RS14805 3007825 3008109 - PTS galactitol transporter subunit IIB phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene2958 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14805 HW43_RS14810 HW43_14375 HW43_RS14810 3008140 3008592 - PTS galactitol transporter subunit IIA phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene2959 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14810 HW43_RS14815 HW43_14380 HW43_RS14815 3008602 3009864 - tagatose-1%2C6-bisphosphate aldolase part of the galacitol catabolism pathway%3B with GatY catalyzes the formation of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate from tagatose-1%2C6-bisphosphate gene gene2960 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14815 HW43_RS14820 HW43_14385 gatY gatY 3009893 3010747 - tagatose-1%2C6-bisphosphate aldolase catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1%2C6-bisphosphate%3B in enteric bacteria there are two D-tagatose 1%2C6-bisphosphate-specific aldolases: KbaY (also called AgaY)%2C involved in catabolism of N-acetyl-galactosamine and D-galactosamine%2C and GatY which is part of the galactitol catabolism pathway gene gene2961 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14820 HW43_RS14825 HW43_14390 HW43_RS14825 3011057 3012109 - fructose-bisphosphate aldolase catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1%2C6-bisphosphate gene gene2962 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14825 HW43_RS14830 HW43_14395 HW43_RS14830 3012366 3013643 + nucleoside transporter low affinity gene gene2963 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14830 HW43_RS14835 HW43_14400 HW43_RS14835 3013640 3014644 + hydrolase gene gene2964 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14835 HW43_RS14840 HW43_14405 HW43_RS14840 3014641 3015606 + kinase gene gene2965 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14840 HW43_RS14845 HW43_14410 HW43_RS14845 3015580 3016326 - transcriptional regulator gene gene2966 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14845 HW43_RS14850 HW43_14415 HW43_RS14850 3016378 3017196 - hydrolase gene gene2967 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14850 HW43_RS14855 HW43_14420 HW43_RS14855 3017261 3018061 - hydroxymethylpyrimidine/phosphomethylpyrimidine kinase catalyzes the formation hydroxymethylpyrimidine phosphate from hydroxymethylpyrimidine and the formation of of 4-amino-2-methyl-5-diphosphomethylpyrimidine from hydroxymethylpyrimidine phosphate gene gene2968 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14855 HW43_RS14860 HW43_14425 HW43_RS14860 3018058 3018846 - hydroxyethylthiazole kinase gene gene2969 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14860 HW43_RS14865 HW43_25340 HW43_RS14865 3019186 3019431 + transcription factor gene gene2970 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14865 HW43_RS14870 HW43_14440 HW43_RS14870 3019627 3020286 - transcriptional regulator gene gene2971 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14870 HW43_RS14875 HW43_14450 HW43_RS14875 3020534 3020722 - hypothetical protein gene gene2972 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14875 HW43_RS14880 HW43_14455 HW43_RS14880 3022710 3023249 + resolvase gene gene2973 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14880 HW43_RS14885 HW43_14460 HW43_RS14885 3023416 3023880 - XRE family transcriptional regulator gene gene2974 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14885 HW43_RS14890 HW43_14465 HW43_RS14890 3023991 3024338 + hypothetical protein gene gene2975 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14890 HW43_RS14895 HW43_14470 HW43_RS14895 3024727 3026298 - hypothetical protein gene gene2976 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14895 HW43_RS14900 HW43_14475 HW43_RS14900 3026398 3027705 - integrase gene gene2977 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14900 HW43_RS14905 HW43_14480 HW43_RS14905 3027959 3028231 - transcriptional regulator DNA-binding%3B binds the RcnA promotor gene gene2978 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14905 HW43_RS14910 HW43_14485 HW43_RS14910 3028352 3029176 + cobalt transporter membrane protein conferring nickel and cobalt resistance gene gene2979 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14910 HW43_RS14915 HW43_14490 HW43_RS14915 3029395 3029733 + nickel/cobalt homeostasis protein RcnB gene gene2980 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14915 HW43_RS14920 HW43_14495 HW43_RS14920 3029815 3030849 - fimbrial protein gene gene2981 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14920 HW43_RS14925 HW43_14500 HW43_RS14925 3030865 3033345 - fimbrial outer membrane usher protein gene gene2982 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14925 HW43_RS14930 HW43_14505 HW43_RS14930 3033361 3034035 - fimbrial assembly chaperone protein StcB gene gene2983 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14930 HW43_RS14935 HW43_14510 HW43_RS14935 3034116 3034658 - hypothetical protein gene gene2984 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14935 HW43_RS14940 HW43_25345 HW43_RS14940 3034847 3035027 + hypothetical protein gene gene2985 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14940 HW43_RS14945 HW43_14515 HW43_RS14945 3034951 3035232 - hypothetical protein gene gene2986 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14945 HW43_RS14950 HW43_14520 HW43_RS14950 3035495 3036604 - protein mrp gene gene2987 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14950 HW43_RS14955 HW43_14525 metG metG 3036736 3038769 + methionine--tRNA ligase methionine--tRNA ligase%3B MetRS%3B adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate%3B some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not%3B four subfamilies exist based on sequence motifs and zinc content gene gene2988 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14955 HW43_RS14960 HW43_14530 HW43_RS14960 3038910 3042704 + hypothetical protein gene gene2989 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14960 HW43_RS14965 HW43_14535 HW43_RS14965 3042714 3046346 + hypothetical protein gene gene2990 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14965 HW43_RS14970 HW43_14540 HW43_RS14970 3046407 3046727 + hypothetical protein gene gene2991 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14970 HW43_RS14975 HW43_25350 HW43_RS14975 3046780 3046869 - hypothetical protein gene gene2992 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14975 HW43_RS14980 HW43_25355 HW43_RS14980 3047388 3047477 - hypothetical protein gene gene2993 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14980 HW43_RS14985 HW43_14555 HW43_RS14985 3047910 3048998 + hypothetical protein gene gene2994 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14985 HW43_RS14990 HW43_14560 HW43_RS14990 3049009 3051288 + hypothetical protein gene gene2995 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14990 HW43_RS14995 HW43_14565 HW43_RS14995 3051281 3052417 + hypothetical protein gene gene2996 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS14995 HW43_RS15000 HW43_25360 HW43_RS15000 3052414 3054428 + hypothetical protein gene gene2997 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15000 HW43_RS15005 HW43_14575 HW43_RS15005 3054553 3055014 + DUF1307 domain-containing protein gene gene2998 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15005 HW43_RS15010 HW43_14580 HW43_RS15010 3055055 3055525 - hypothetical protein gene gene2999 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15010 HW43_RS15015 HW43_14585 HW43_RS15015 3055572 3056291 - two-component system response regulator unknown function%3B when overproduced it confers drug-resistance gene gene3000 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15015 HW43_RS15020 HW43_14590 HW43_RS15020 3056288 3057973 - sensor histidine kinase gene gene3001 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15020 HW43_RS15025 HW43_14595 HW43_RS15025 3058488 3058736 + DNA-damage-inducible protein DinI gene gene3002 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15025 HW43_RS15030 HW43_14600 HW43_RS15030 3059006 3059680 - caudovirales tail fiber assembly protein gene gene3003 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15030 HW43_RS15035 HW43_14605 HW43_RS15035 3059692 3059904 - tail fiber assembly protein gene gene3004 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15035 HW43_RS15045 HW43_14615 HW43_RS15045 3061771 3061911 - hypothetical protein gene gene3006 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15045 HW43_RS15050 HW43_14620 HW43_RS15050 3062110 3065796 - tail fiber protein gene gene3007 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15050 HW43_RS15055 HW43_14625 HW43_RS15055 3066707 3067387 - tail assembly protein gene gene3008 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15055 HW43_RS15060 HW43_14630 HW43_RS15060 3067285 3068028 - tail protein gene gene3009 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15060 HW43_RS15065 HW43_14635 HW43_RS15065 3068039 3068737 - tail protein gene gene3010 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15065 HW43_RS15070 HW43_14640 HW43_RS15070 3068737 3069066 - tail protein gene gene3011 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15070 HW43_RS15075 HW43_25380 HW43_RS15075 3069063 3071642 - tail protein gene gene3012 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15075 HW43_RS15080 HW43_14650 HW43_RS15080 3071623 3072036 - phage tail protein gene gene3013 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15080 HW43_RS15085 HW43_14655 HW43_RS15085 3072063 3072494 - tail protein gene gene3014 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15085 HW43_RS15090 HW43_14660 HW43_RS15090 3072510 3073259 - tail protein gene gene3015 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15090 HW43_RS15095 HW43_14665 HW43_RS15095 3073267 3073662 - tail protein gene gene3016 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15095 HW43_RS15100 HW43_14670 HW43_RS15100 3073659 3074234 - tail protein gene gene3017 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15100 HW43_RS15105 HW43_14675 HW43_RS15105 3074250 3074603 - tail attachment protein gene gene3018 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15105 HW43_RS15110 HW43_14680 HW43_RS15110 3074596 3074979 - hypothetical protein gene gene3019 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15110 HW43_RS15115 HW43_14685 HW43_RS15115 3075031 3076059 - head protein gene gene3020 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15115 HW43_RS15120 HW43_14690 HW43_RS15120 3076117 3076464 - Head decoration protein gene gene3021 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15120 HW43_RS15125 HW43_14695 HW43_RS15125 3076500 3078005 - phage capsid assembly protein gene gene3022 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15125 HW43_RS15130 HW43_14700 HW43_RS15130 3077995 3079587 - chromosome partitioning protein ParB gene gene3023 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15130 HW43_RS15135 HW43_14705 HW43_RS15135 3079584 3079790 - head-tail joining protein gene gene3024 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15135 HW43_RS15140 HW43_14710 HW43_RS15140 3079774 3081702 - terminase gene gene3025 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15140 HW43_RS15145 HW43_14715 HW43_RS15145 3081674 3082222 - terminase gene gene3026 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15145 HW43_RS15150 HW43_RS15150 HW43_RS15150 3082545 3082662 + arginyl-tRNA synthetase gene gene3027 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15150 HW43_RS15155 HW43_14720 HW43_RS15155 3082897 3083427 - Rha family transcriptional regulator gene gene3028 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15155 HW43_RS15160 HW43_14725 HW43_RS15160 3083630 3084067 - endopeptidase gene gene3029 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15160 HW43_RS15165 HW43_14730 HW43_RS15165 3084070 3084219 - hypothetical protein gene gene3030 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15165 HW43_RS15170 HW43_14735 HW43_RS15170 3084219 3084791 - antirepressor gene gene3031 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15170 HW43_RS15175 HW43_14740 HW43_RS15175 3085066 3085599 - lysozyme gene gene3032 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15175 HW43_RS15180 HW43_14745 HW43_RS15180 3085730 3086071 + hypothetical protein gene gene3033 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15180 HW43_RS15185 HW43_14750 HW43_RS15185 3086110 3086901 - hypothetical protein gene gene3034 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15185 HW43_RS15190 HW43_14755 HW43_RS15190 3086905 3087120 - holin gene gene3035 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15190 HW43_RS15195 HW43_14765 HW43_RS15195 3087615 3089579 - 9-O-acetyl-N-acetylneuraminic acid deacetylase gene gene3036 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15195 HW43_RS15200 HW43_25390 HW43_RS15200 3089823 3090146 + anti-adapter protein IraM interacts RssB preventing the degradation of the stress sigma factor RpoS gene gene3037 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15200 HW43_RS15205 HW43_14770 HW43_RS15205 3090444 3090713 - Shiga toxin subunit B gene gene3038 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15205 HW43_RS15210 HW43_14775 HW43_RS15210 3090725 3091684 - shiga-like toxin 2 subunit A gene gene3039 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15210 HW43_RS15215 HW43_14780 HW43_RS15215 3091775 3091851 - tRNA-Arg tRNA gene3040 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15215 HW43_RS15220 HW43_14785 HW43_RS15220 3091865 3091941 - tRNA-Arg tRNA gene3041 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15220 HW43_RS15225 HW43_14790 HW43_RS15225 3091951 3092026 - tRNA-Met tRNA gene3042 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15225 HW43_RS15230 HW43_14795 HW43_RS15230 3092067 3093125 - DNA adenine methylase gene gene3043 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15230 HW43_RS15235 HW43_14800 HW43_RS15235 3093276 3093473 - hypothetical protein gene gene3044 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15235 HW43_RS15240 HW43_14805 HW43_RS15240 3093708 3094325 - hypothetical protein gene gene3045 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15240 HW43_RS15245 HW43_14810 HW43_RS15245 3094392 3094784 - antitermination protein Q gene gene3046 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15245 HW43_RS15250 HW43_14815 HW43_RS15250 3094802 3095791 - hypothetical protein gene gene3047 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15250 HW43_RS15255 HW43_14820 HW43_RS15255 3095844 3096101 - hypothetical protein gene gene3048 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15255 HW43_RS15260 HW43_14825 HW43_RS15260 3096098 3097498 - helicase gene gene3049 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15260 HW43_RS15265 HW43_14830 HW43_RS15265 3097495 3098373 - ATPase AAA gene gene3050 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15265 HW43_RS15270 HW43_14835 HW43_RS15270 3098384 3099376 - replication protein gene gene3051 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15270 HW43_RS15275 HW43_14840 HW43_RS15275 3099373 3099699 - hypothetical protein gene gene3052 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15275 HW43_RS15280 HW43_14845 HW43_RS15280 3099696 3099920 - hypothetical protein gene gene3053 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15280 HW43_RS15285 HW43_14850 HW43_RS15285 3099917 3100768 - peptidase gene gene3054 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15285 HW43_RS15290 HW43_14855 HW43_RS15290 3100765 3101589 - transporter gene gene3055 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15290 HW43_RS15295 HW43_14860 HW43_RS15295 3101642 3102349 - DNA-binding protein gene gene3056 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15295 HW43_RS15300 HW43_14865 HW43_RS15300 3102431 3102664 - Cro/Cl family transcriptional regulator gene gene3057 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15300 HW43_RS15305 HW43_14870 HW43_RS15305 3102821 3103510 + hypothetical protein gene gene3058 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15305 HW43_RS15310 HW43_14875 HW43_RS15310 3103658 3104359 + DNA-binding protein gene gene3059 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15310 HW43_RS15315 HW43_14880 HW43_RS15315 3104356 3104556 + hypothetical protein gene gene3060 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15315 HW43_RS15320 HW43_14885 HW43_RS15320 3104755 3104937 + hypothetical protein gene gene3061 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15320 HW43_RS15325 HW43_14890 HW43_RS15325 3104943 3105515 + hypothetical protein gene gene3062 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15325 HW43_RS15330 HW43_14895 HW43_RS15330 3105700 3105888 + hypothetical protein gene gene3063 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15330 HW43_RS15335 HW43_14900 HW43_RS15335 3105885 3106712 + hypothetical protein gene gene3064 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15335 HW43_RS15340 HW43_14905 HW43_RS15340 3106753 3107124 + hypothetical protein gene gene3065 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15340 HW43_RS15345 HW43_25395 HW43_RS15345 3107316 3107570 + excisionase gene gene3066 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15345 HW43_RS15350 HW43_14920 HW43_RS15350 3107604 3108890 + integrase gene gene3067 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15350 HW43_RS15355 HW43_14925 HW43_RS15355 3108926 3109612 + MerR family transcriptional regulator gene gene3068 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15355 HW43_RS15360 HW43_25400 HW43_RS15360 3109672 3109779 + membrane protein gene gene3069 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15360 HW43_RS15365 HW43_14935 HW43_RS15365 3109760 3110491 - osmoprotectant uptake system permease gene gene3070 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15365 HW43_RS15370 HW43_14940 HW43_RS15370 3110496 3111422 - ATP-binding protein gene gene3071 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15370 HW43_RS15375 HW43_14945 HW43_RS15375 3111415 3112572 - osmoprotectant uptake system permease gene gene3072 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15375 HW43_RS15380 HW43_14950 HW43_RS15380 3112579 3113496 - osmoprotectant uptake system substrate-binding protein gene gene3073 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15380 HW43_RS15385 HW43_14955 HW43_RS15385 3113707 3116004 - beta-D-glucoside glucohydrolase catalyzes the hydrolysis of terminal beta-D-glucosyl residues gene gene3074 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15385 HW43_RS15390 HW43_14960 HW43_RS15390 3116200 3117915 + lactate dehydrogenase component of the membrane-bound D-lactate oxidase%2C FAD-binding%2C NADH independent gene gene3075 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15390 HW43_RS15395 HW43_14965 pbpG pbpG 3117954 3118886 - D-alanyl-D-alanine endopeptidase specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi%3B Penicillin-binding protein 7 gene gene3076 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15395 HW43_RS15400 HW43_14970 HW43_RS15400 3119060 3119647 - hypothetical protein gene gene3077 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15400 HW43_RS15405 HW43_14975 HW43_RS15405 3119817 3120395 + hypothetical protein gene gene3078 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15405 HW43_RS15410 HW43_14980 HW43_RS15410 3120525 3121286 - oxidoreductase gene gene3079 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15410 HW43_RS15415 HW43_14985 HW43_RS15415 3121339 3122775 - multidrug resistance outer membrane protein MdtQ may be involved in resistance to puromycin%2C acriflavine and tetraphenylarsonium chloride gene gene3080 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15415 HW43_RS15420 HW43_25405 HW43_RS15420 3122999 3123082 + hypothetical protein gene gene3081 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15420 HW43_RS15425 HW43_14995 HW43_RS15425 3123470 3124420 - tRNA-dihydrouridine synthase C gene gene3082 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15425 HW43_RS15430 HW43_15000 HW43_RS15430 3124659 3125057 + hypothetical protein gene gene3083 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15430 HW43_RS15435 HW43_15005 HW43_RS15435 3125054 3125749 + hypothetical protein gene gene3084 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15435 HW43_RS15440 HW43_15010 HW43_RS15440 3125879 3126763 + cytidine deaminase Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis gene gene3085 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15440 HW43_RS15445 HW43_15015 HW43_RS15445 3126913 3127632 + protein SanA involved in vancomycin sensitivity and other barrier functions of the cell envelope gene gene3086 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15445 HW43_RS15450 HW43_15020 HW43_RS15450 3127635 3127874 + DUF2542 domain-containing protein gene gene3087 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15450 HW43_RS15455 HW43_15025 HW43_RS15455 3128193 3129431 + dihydropyrimidine dehydrogenase subunit A gene gene3088 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15455 HW43_RS15460 HW43_15030 HW43_RS15460 3129425 3130660 + dihydropyrimidine dehydrogenase subunit B gene gene3089 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15460 HW43_RS15465 HW43_15035 mglC mglC 3130731 3131741 - galactoside ABC transporter permease ABC transporter%3B functions in galactose transport%3B part of MglA2C2B transporter complex gene gene3090 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15465 HW43_RS15470 HW43_15040 HW43_RS15470 3131757 3133277 - galactose/methyl galactoside import ATP-binding protein MglA gene gene3091 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15470 HW43_RS15475 HW43_15045 HW43_RS15475 3133338 3134336 - D-galactose-binding periplasmic protein wtih MglAC is involved in the transport of beta-methylgalactoside gene gene3092 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15475 HW43_RS15480 HW43_15050 HW43_RS15480 3134616 3135656 - transcriptional regulator controls transcription of galETKM gene gene3093 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15480 HW43_RS15485 HW43_25410 HW43_RS15485 3135646 3135849 + hypothetical protein gene gene3094 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15485 HW43_RS15490 HW43_15055 HW43_RS15490 3135798 3136955 - membrane protein gene gene3095 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15490 HW43_RS15495 HW43_15060 folE folE 3136972 3137640 - GTP cyclohydrolase 1 involved in the first step of tetrahydrofolate biosynthesis%3B catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1%2C2%2C3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water%3B forms a homopolymer gene gene3096 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15495 HW43_RS15500 HW43_25415 HW43_RS15500 3137794 3137970 + hypothetical protein gene gene3097 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15500 HW43_RS15505 HW43_15065 HW43_RS15505 3137898 3138734 + S-formylglutathione hydrolase YeiG gene gene3098 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15505 HW43_RS15510 HW43_25420 HW43_RS15510 3138766 3140758 - catecholate siderophore receptor CirA Cir%3B FeuA%3B CirA%3B receptor protein for siderophores (colicin IA%2C IB and V) and microcins (E492%2C H47%2C and M)%3B TonB-dependent%3B able to transport monomers%2C dimer%2C and linear trimers of 2%2C3-dihydorxybenzoylserine%3B outer membrane protein gene gene3099 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15510 HW43_RS15515 HW43_25425 HW43_RS15515 3140751 3140954 - hypothetical protein gene gene3100 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15515 HW43_RS15520 HW43_15075 HW43_RS15520 3141051 3142520 - lysine-specific permease gene gene3101 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15520 HW43_RS15525 HW43_15080 HW43_RS15525 3142725 3143606 - transcriptional regulator gene gene3102 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15525 HW43_RS15530 HW43_15085 HW43_RS15530 3143705 3144754 + membrane protein gene gene3103 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15530 HW43_RS15535 HW43_15090 HW43_RS15535 3144828 3145685 + endonuclease Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues gene gene3104 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15535 HW43_RS15540 HW43_15095 HW43_RS15540 3145689 3146777 + carbohydrate kinase gene gene3105 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15540 HW43_RS15545 HW43_15100 HW43_RS15545 3146833 3148083 - nucleoside permease gene gene3106 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15545 HW43_RS15550 HW43_15105 rihB rihB 3148183 3149124 - pyrimidine-specific ribonucleoside hydrolase RihB Hydrolyzes cytidine or uridine to ribose and cytosine or uracil%2C respectively gene gene3107 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15550 HW43_RS15555 HW43_15110 HW43_RS15555 3149254 3149952 + Crp/Fnr family transcriptional regulator activator of nucleoside metabolism gene gene3108 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15555 HW43_RS15560 HW43_15115 HW43_RS15560 3150020 3151270 - nucleoside transporter gene gene3109 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15560 HW43_RS15565 HW43_15120 HW43_RS15565 3151364 3152302 - pseudouridine-5'-phosphate glycosidase gene gene3110 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15565 HW43_RS15570 HW43_15125 HW43_RS15570 3152290 3153231 - pseudouridine kinase gene gene3111 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15570 HW43_RS15575 HW43_15130 HW43_RS15575 3153655 3155346 - PTS fructose transporter subunit IIBC phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene3112 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15575 HW43_RS15580 HW43_15135 fruK fruK 3155363 3156301 - 1-phosphofructokinase converts fructose-1-phosphate and ATP to fructose-1%2C6-bisphosphate and ADP%3B highly specific for fructose-1-phopshate%3B similar to PfkB%3B forms homodimers gene gene3113 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15580 HW43_RS15585 HW43_15140 HW43_RS15585 3156301 3157431 - PTS fructose transporter subunit IIA phosphoenolpyruvate (PEP)-dependent%2C sugar transporting phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIA is phosphorylated by phospho-HPr which then transfers the phosphoryl group to the IIB component gene gene3114 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15585 HW43_RS15590 HW43_15150 HW43_RS15590 3157799 3158980 + sugar transporter gene gene3115 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15590 HW43_RS15595 HW43_15155 HW43_RS15595 3158977 3159231 - hypothetical protein gene gene3116 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15595 HW43_RS15600 HW43_15160 HW43_RS15600 3159386 3159958 + elongation factor P-like protein Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro%2C suggesting its involvement in the formation of the first peptide bond of a protein gene gene3117 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15600 HW43_RS15605 HW43_15165 HW43_RS15605 3160181 3161647 + D-mannonate oxidoreductase gene gene3118 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15605 HW43_RS15610 HW43_15170 HW43_RS15610 3161765 3162751 + hypothetical protein gene gene3119 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15610 HW43_RS15615 HW43_15175 HW43_RS15615 3162790 3163503 + lipid A 1-diphosphate synthase gene gene3120 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15615 HW43_RS15620 HW43_15180 spr spr 3163915 3164481 + murein DD-endopeptidase MepS/Murein LD-carboxypeptidase mutational suppressor of prc thermosensitivity gene gene3121 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15620 HW43_RS15625 HW43_15185 HW43_RS15625 3164662 3166218 + phage resistance protein involved in resistance to the phages N4 and lambda gene gene3122 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15625 HW43_RS15630 HW43_15190 HW43_RS15630 3166300 3168114 + peptide ABC transporter substrate-binding protein with YejBEF is involved in resistance to microcin C gene gene3123 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15630 HW43_RS15635 HW43_15195 HW43_RS15635 3168115 3169209 + microcin C ABC transporter permease YejB with YejAEF is involved in resistance to microcin C gene gene3124 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15635 HW43_RS15640 HW43_15200 HW43_RS15640 3169209 3170234 + microcin C ABC transporter permease part of the microcin C transport system gene gene3125 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15640 HW43_RS15645 HW43_15205 HW43_RS15645 3170236 3171825 + microcin C ABC transporter ATP-binding protein YejF with YejAEF is involved in resistance to microcin C gene gene3126 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15645 HW43_RS15650 HW43_15210 HW43_RS15650 3171829 3172173 - hypothetical protein gene gene3127 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15650 HW43_RS15655 HW43_15215 HW43_RS15655 3172506 3173696 - Bcr/CflA family drug resistance efflux transporter Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance gene gene3128 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15655 HW43_RS15660 HW43_15220 HW43_RS15660 3173724 3174419 - ribosomal small subunit pseudouridine synthase A catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA gene gene3129 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15660 HW43_RS15665 HW43_15225 HW43_RS15665 3174568 3176328 + hypothetical protein gene gene3130 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15665 HW43_RS15670 HW43_15230 HW43_RS15670 3176453 3176737 + 50S ribosomal protein L25 gene gene3131 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15670 HW43_RS15675 HW43_15235 HW43_RS15675 3176876 3177883 - nucleoid-associated protein gene gene3132 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15675 HW43_RS15680 HW43_15240 HW43_RS15680 3178065 3178292 + hypothetical protein gene gene3133 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15680 HW43_RS15685 HW43_15245 HW43_RS15685 3178312 3180072 + membrane protein gene gene3134 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15685 HW43_RS15690 HW43_15250 HW43_RS15690 3180147 3180223 + tRNA-Pro tRNA gene3135 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15690 HW43_RS15695 HW43_25430 HW43_RS15695 3180327 3180539 - ATPase gene gene3136 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15695 HW43_RS15700 HW43_15260 HW43_RS15700 3180552 3182837 - membrane protein gene gene3137 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15700 HW43_RS15705 HW43_25435 HW43_RS15705 3182949 3183206 - hypothetical protein gene gene3138 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15705 HW43_RS15710 HW43_15265 HW43_RS15710 3183238 3183885 + transcriptional regulator nitrate/nitrite response regulator NarP%3B NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems%3B represses expression of other anaerobic genes gene gene3139 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15710 HW43_RS15715 HW43_15270 HW43_RS15715 3183920 3184972 - heme lyase subunit CcmH cytochrome c-type biogenesis protein%3B involved in the attachment of heme to cytochrome c gene gene3140 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15715 HW43_RS15720 HW43_15275 HW43_RS15720 3184969 3185526 - thiol:disulfide interchange protein DsbE cytochrome c-type biogenesis thioredoxin%3B involved in the reduction of disulfide bonds to allow heme bonding gene gene3141 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15720 HW43_RS15725 HW43_15280 HW43_RS15725 3185523 3187466 - heme lyase subunit CcmF cytochrome c-type biogenesis protein%3B required for the transfer of heme to apocytochrome c gene gene3142 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15725 HW43_RS15730 HW43_15285 HW43_RS15730 3187463 3187942 - cytochrome c-type biogenesis protein CcmE CycJ%3B periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes%3B requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome%3B part of the cytochrome c maturation system%3B periplasmic protein anchored to the inner membrane gene gene3143 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15730 HW43_RS15735 HW43_15290 HW43_RS15735 3187939 3188148 - heme exporter protein D is invovled in heme transfer during cytochrome c biogenesis%3B acts to stabilize CcmC and CcmE gene gene3144 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15735 HW43_RS15740 HW43_15295 HW43_RS15740 3188145 3188882 - heme exporter protein C with CcmABDE is involved in the transport of protoheme IX%3B CcmC is required for heme transfer to CcmE gene gene3145 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15740 HW43_RS15745 HW43_15300 HW43_RS15745 3188924 3189583 - heme ABC transporter permease with CcmABCE is involved in the transport of protoheme IX%3B CcmB is required for the release of holoCcmE from CcmC gene gene3146 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15745 HW43_RS15750 HW43_15305 HW43_RS15750 3189583 3190200 - cytochrome C biogenesis protein CcmA gene gene3147 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15750 HW43_RS15755 HW43_15310 HW43_RS15755 3190219 3190821 - cytochrome c-type protein NapC with NapABDFGH functions as a nitrate reductase%3B NapC functions as an electron shuttle between NapAB and NapGH or quinone gene gene3148 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15755 HW43_RS15760 HW43_15315 napB napB 3190831 3191280 - nitrate reductase cytochrome C550 subunit small subunit of periplasmic nitrate reductase%3B receives electrons from the membrane-bound NapC and passes them to NapA gene gene3149 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15760 HW43_RS15765 HW43_15320 napH napH 3191277 3192140 - ferredoxin-type protein NapH part of NapHG quinol dehydrogenase%3B couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA gene gene3150 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15765 HW43_RS15770 HW43_15325 napG napG 3192127 3192822 - ferredoxin-type protein NapG part of NapHG quinol dehydrogenase%3B couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA%3B secreted by twin arginine translocation pathway gene gene3151 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15770 HW43_RS15775 HW43_15330 HW43_RS15775 3192829 3195315 - periplasmic nitrate reductase periplasmic%3B catalytic subunit%3B with NapBC catalyzes the reduction of nitrate to nitrite%3B NapAB receives electrons from NapC gene gene3152 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15775 HW43_RS15780 HW43_15335 HW43_RS15780 3195312 3195575 - protein NapD gene gene3153 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15780 HW43_RS15785 HW43_15340 HW43_RS15785 3195565 3196059 - ferredoxin-type protein NapF Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA. gene gene3154 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15785 HW43_RS15790 HW43_25440 HW43_RS15790 3196168 3196332 + hypothetical protein gene gene3155 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15790 HW43_RS15795 HW43_15345 HW43_RS15795 3196467 3196955 + ecotin serine protease inhibitor%2C inhibits trypsin and other proteases gene gene3156 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15795 HW43_RS15800 HW43_15350 HW43_RS15800 3197104 3198750 - malate:quinone oxidoreductase gene gene3157 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15800 HW43_RS15805 HW43_15355 HW43_RS15805 3198968 3200611 - ABC transporter ATP-binding protein efflux pump for the antibacterial peptide microcin J25 gene gene3158 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15805 HW43_RS15810 HW43_15360 HW43_RS15810 3200687 3201337 - alpha-ketoglutarate-dependent dioxygenase gene gene3159 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15810 HW43_RS15815 HW43_15365 HW43_RS15815 3201337 3202401 - transcriptional regulator regulates genes involved in the repair of alkylated DNA%3B repairs DNA containing 6-O-methylguanine gene gene3160 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15815 HW43_RS15820 HW43_15370 HW43_RS15820 3202475 3203530 - thiamine biosynthesis lipoprotein ApbE catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine%3B involved in the maintenance and/or assembly of sulfur clusters%3B periplasmic lipoporotein anchored to the inner membrane%3B part of the thiamine pyrophosphate biosynthesis pathway gene gene3161 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15820 HW43_RS15825 HW43_15375 HW43_RS15825 3203642 3204745 - porin gene gene3162 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15825 HW43_RS15830 HW43_25445 HW43_RS15830 3205004 3205096 - glutamate decarboxylase gene gene3163 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15830 HW43_RS15835 HW43_25450 HW43_RS15835 3205137 3205262 - hypothetical protein gene gene3164 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15835 HW43_RS15840 HW43_15380 HW43_RS15840 3205484 3208156 + phosphotransfer intermediate protein in two-component regulatory system with RcsBC gene gene3165 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15840 HW43_RS15845 HW43_15385 HW43_RS15845 3208173 3208823 + transcriptional regulator two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division%3B probably phosphorylated by RcsC or RcsF gene gene3166 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15845 HW43_RS15850 HW43_15390 HW43_RS15850 3209023 3211872 - sensor histidine kinase gene gene3167 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15850 HW43_RS15855 HW43_15395 HW43_RS15855 3212147 3212923 - hypothetical protein gene gene3168 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15855 HW43_RS15860 HW43_15400 HW43_RS15860 3212928 3214577 - hypothetical protein gene gene3169 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15860 HW43_RS15865 HW43_15405 HW43_RS15865 3214578 3219092 - hypothetical protein gene gene3170 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15865 HW43_RS15870 HW43_15410 HW43_RS15870 3219116 3219739 - hypothetical protein gene gene3171 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15870 HW43_RS15875 HW43_15415 HW43_RS15875 3219736 3221424 - hypothetical protein gene gene3172 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15875 HW43_RS15880 HW43_15420 HW43_RS15880 3221573 3224200 - DNA gyrase subunit A gene gene3173 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15880 HW43_RS15885 HW43_15425 HW43_RS15885 3224347 3225069 + ubiquinone biosynthesis O-methyltransferase Involved in ubiquinone biosynthesis gene gene3174 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15885 HW43_RS15890 HW43_15430 HW43_RS15890 3225197 3228931 - adhesin gene gene3175 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15890 HW43_RS15895 HW43_25455 HW43_RS15895 3229403 3229546 + hypothetical protein gene gene3176 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15895 HW43_RS15900 HW43_15435 HW43_RS15900 3229627 3231912 + ribonucleotide-diphosphate reductase subunit alpha Catalyzes the rate-limiting step in dNTP synthesis gene gene3177 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15900 HW43_RS15905 HW43_15440 HW43_RS15905 3232059 3233189 + ribonucleotide-diphosphate reductase subunit beta B2 or R2 protein%3B type 1a enzyme%3B catalyzes the rate-limiting step in dNTP synthesis%3B converts nucleotides to deoxynucleotides%3B forms a homodimer and then a multimeric complex with NrdA gene gene3178 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15905 HW43_RS15910 HW43_15445 HW43_RS15910 3233189 3233443 + ferredoxin involved with ribonucleotide reductase diferric-tyrosyl radical (Y*) cofactor maintenance plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor%2C essential for nucleotide reduction catalyzed by ribonucleotide reductases gene gene3179 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15910 HW43_RS15915 HW43_15450 HW43_RS15915 3233497 3234147 - protein InaA gene gene3180 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15915 HW43_RS15920 HW43_25460 HW43_RS15920 3234362 3234568 + hypothetical protein gene gene3181 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15920 HW43_RS15925 HW43_15455 glpQ glpQ 3234610 3235686 - glycerophosphodiester phosphodiesterase hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols%3B periplasmic gene gene3182 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15925 HW43_RS15930 HW43_15460 glpT glpT 3235691 3237049 - sn-glycerol-3-phosphate transporter catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell gene gene3183 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15930 HW43_RS15935 HW43_15465 glpA glpA 3237322 3238950 + anaerobic glycerol-3-phosphate dehydrogenase subunit A anaerobic%2C catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor gene gene3184 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15935 HW43_RS15940 HW43_15470 HW43_RS15940 3238940 3240199 + anaerobic glycerol-3-phosphate dehydrogenase subunit B sn-glycerol-3-phosphate dehydrogenase (anaerobic)%3B catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate%3B part of GlpABC complex%3B presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters gene gene3185 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15940 HW43_RS15945 HW43_15475 glpC glpC 3240196 3241386 + sn-glycerol-3-phosphate dehydrogenase subunit C anaerobic%3B with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate gene gene3186 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15945 HW43_RS15950 HW43_15480 HW43_RS15950 3241580 3242482 + hypothetical protein gene gene3187 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15950 HW43_RS15955 HW43_15485 HW43_RS15955 3242523 3242912 - aldolase gene gene3188 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15955 HW43_RS15960 HW43_15490 HW43_RS15960 3243048 3244250 - cinA-like protein gene gene3189 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15960 HW43_RS15965 HW43_15495 HW43_RS15965 3244350 3244892 - membrane protein gene gene3190 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15965 HW43_RS15970 HW43_15500 HW43_RS15970 3245171 3245596 + nucleoside triphosphatase catalyzes the hydrolysis of nucleoside triphosphates gene gene3191 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15970 HW43_RS15975 HW43_15505 HW43_RS15975 3245635 3246237 - LPS core heptose(II)-phosphate phosphatase catalyzes the of heptose(II) of the outer membrane lipopolysaccharide core gene gene3192 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15975 HW43_RS15980 HW43_15510 HW43_RS15980 3246545 3247684 + UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose gene gene3193 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15980 HW43_RS15985 HW43_15515 HW43_RS15985 3247688 3248656 + undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate gene gene3194 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15985 HW43_RS15990 HW43_15520 HW43_RS15990 3248656 3250638 + bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase Bifunctional polymyxin resistance arnA protein%3B catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose%3B active in certain mutant strains gene gene3195 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15990 HW43_RS15995 HW43_15525 HW43_RS15995 3250635 3251525 + 4-deoxy-4-formamido-L-arabinose-phospho-UDP deformylase catalyzes the formation of 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol from 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol gene gene3196 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS15995 HW43_RS16000 HW43_15530 arnT arnT 3251525 3253177 + undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A gene gene3197 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16000 HW43_RS16005 HW43_15535 HW43_RS16005 3253174 3253509 + 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE with ArnE is involved in transporting 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol from the cytoplasmic face to the periplasmic face of the inner membrane gene gene3198 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16005 HW43_RS16010 HW43_15540 HW43_RS16010 3253509 3253895 + 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF with ArnE is responsible for the transport of 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol from the cytoplasm to the periplasm gene gene3199 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16010 HW43_RS16015 HW43_15545 HW43_RS16015 3253889 3254155 - signal transduction protein PmrD with BasR regulates genes involved in polymyxin resistance gene gene3200 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16015 HW43_RS16020 HW43_15550 HW43_RS16020 3254265 3255620 - O-succinylbenzoic acid--CoA ligase gene gene3201 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16020 HW43_RS16025 HW43_15555 HW43_RS16025 3255617 3256579 - o-succinylbenzoate synthase catalyzes the dehydration of 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate gene gene3202 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16025 HW43_RS16030 HW43_15560 HW43_RS16030 3256579 3257436 - 1%2C4-dihydroxy-2-naphthoyl-CoA synthase catalyzes the formation of 1%2C4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA gene gene3203 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16030 HW43_RS16035 HW43_15565 HW43_RS16035 3257451 3258209 - 2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate synthase catalyzes the formation of (1 R%2C6 R)-2-succinyl-6-hydroxy-2%2C4-cyclohexadiene-1-carboxylate in menaquinone biosynthesis gene gene3204 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16035 HW43_RS16040 HW43_15570 HW43_RS16040 3258206 3259876 - 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase SEPHCHC synthase%3B forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis gene gene3205 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16040 HW43_RS16045 HW43_15575 HW43_RS16045 3259965 3261260 - isochorismate synthase gene gene3206 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16045 HW43_RS16050 HW43_15580 HW43_RS16050 3261339 3261644 - protein ElaB gene gene3207 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16050 HW43_RS16055 HW43_15585 HW43_RS16055 3261699 3262160 - protein ElaA gene gene3208 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16055 HW43_RS16060 HW43_15590 HW43_RS16060 3262225 3263142 + hypothetical protein RNase BN%3B member of metallo-beta-lactamase family%3B the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase%3B in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not%3B associates with two zinc ions gene gene3209 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16060 HW43_RS16065 HW43_15595 HW43_RS16065 3263333 3264550 + deubiquitinase ElaD%3B specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins%3B SseL in Salmonella is required for macrophage killing and virulence%2C and it is secreted by the salmonella pathogenicity island 2 type III secretion system gene gene3210 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16065 HW43_RS16070 HW43_15600 HW43_RS16070 3265366 3265545 + aminopeptidase gene gene3211 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16070 HW43_RS16075 HW43_15605 HW43_RS16075 3265671 3266174 + hypothetical protein gene gene3212 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16075 HW43_RS16080 HW43_15610 HW43_RS16080 3266241 3267698 - NADH-quinone oxidoreductase subunit N Catalyzes the transfer of electrons from NADH to quinone gene gene3213 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16080 HW43_RS16085 HW43_15615 HW43_RS16085 3267705 3269234 - NADH-quinone oxidoreductase subunit M gene gene3214 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16085 HW43_RS16090 HW43_15620 HW43_RS16090 3269398 3271239 - NADH:ubiquinone oxidoreductase subunit L Catalyzes the transfer of electrons from NADH to ubiquinone gene gene3215 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16090 HW43_RS16095 HW43_15625 HW43_RS16095 3271236 3271538 - NADH-quinone oxidoreductase subunit K gene gene3216 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16095 HW43_RS16100 HW43_15630 HW43_RS16100 3271535 3272089 - NADH-quinone oxidoreductase subunit J Catalyzes the transfer of electrons from NADH to quinone gene gene3217 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16100 HW43_RS16105 HW43_15635 HW43_RS16105 3272101 3272643 - NADH-quinone oxidoreductase subunit I gene gene3218 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16105 HW43_RS16110 HW43_15640 HW43_RS16110 3272658 3273635 - NADH-quinone oxidoreductase subunit H gene gene3219 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16110 HW43_RS16115 HW43_15645 HW43_RS16115 3273632 3276358 - NADH dehydrogenase subunit G Catalyzes the transfer of electrons from NADH to quinone gene gene3220 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16115 HW43_RS16120 HW43_15650 HW43_RS16120 3276411 3277748 - NADH dehydrogenase subunit F part of NADH-ubiquinone oxidoreductase complex I%3B shuttles electrons from NADH%2C via FMN and iron-sulfur (Fe-S) centers%2C to quinones in the respiratory chain%3B NuoF is part of the soluble NADH dehydrogenase fragment%2C which represents the electron input part of NADH dehydrogenase gene gene3221 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16120 HW43_RS16125 HW43_15655 HW43_RS16125 3277745 3278245 - NADH-quinone oxidoreductase subunit E Catalyzes the transfer of electrons from NADH to quinone gene gene3222 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16125 HW43_RS16130 HW43_15660 HW43_RS16130 3278248 3280038 - NADH-quinone oxidoreductase subunit C/D NuoCD%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron-sulfur (Fe-S) centers%2C to quinones in the respiratory chain%3B subunits NuoCD%2C E%2C F%2C and G constitute the peripheral sector of the complex%3B in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms gene gene3223 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16130 HW43_RS16135 HW43_15665 HW43_RS16135 3280144 3280806 - NADH-quinone oxidoreductase subunit B gene gene3224 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16135 HW43_RS16140 HW43_15670 HW43_RS16140 3280822 3281265 - NADH-quinone oxidoreductase subunit A gene gene3225 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16140 HW43_RS16145 HW43_15675 HW43_RS16145 3281896 3282834 - transcriptional regulator involved in the regulation of genes involved in flagella synthesis%2C motility and chemotaxis gene gene3226 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16145 HW43_RS16150 HW43_15680 HW43_RS16150 3283754 3284971 + glutamate--pyruvate aminotransferase AlaA broad specificity%3B family IV%3B in Corynebacterium glutamicum this protein can use glutamate%2C 2-aminobutyrate%2C and aspartate as amino donors and pyruvate as the acceptor gene gene3227 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16150 HW43_RS16155 HW43_15685 HW43_RS16155 3285055 3285654 + 5'-deoxynucleotidase YfbR gene gene3228 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16155 HW43_RS16160 HW43_15690 HW43_RS16160 3285713 3287545 - transporter gene gene3229 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16160 HW43_RS16165 HW43_15695 HW43_RS16165 3287632 3288282 - phosphatase gene gene3230 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16165 HW43_RS16170 HW43_15700 HW43_RS16170 3288293 3288787 - hypothetical protein gene gene3231 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16170 HW43_RS16175 HW43_15705 HW43_RS16175 3288870 3289325 - membrane protein gene gene3232 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16175 HW43_RS16180 HW43_25465 HW43_RS16180 3289394 3289525 - hypothetical protein gene gene3233 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16180 HW43_RS16185 HW43_15715 HW43_RS16185 3289663 3290865 + acetate kinase AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation%3B utilizes magnesium and ATP%3B also involved in conversion of acetate to aceyl-CoA%3B also known to act on propionate gene gene3234 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16185 HW43_RS16190 HW43_15720 HW43_RS16190 3290940 3293084 + phosphate acetyltransferase catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate%3B when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate gene gene3235 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16190 HW43_RS16195 HW43_15725 HW43_RS16195 3293274 3294794 + inner membrane transporter%3B C4-dicarboxylate anaerobic carrier family protein gene gene3236 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16195 HW43_RS16200 HW43_15730 HW43_RS16200 3294827 3295369 - NUDIX hydrolase gene gene3237 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16200 HW43_RS16205 HW43_15735 HW43_RS16205 3295427 3295978 - phosphodiesterase gene gene3238 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16205 HW43_RS16210 HW43_15740 HW43_RS16210 3296034 3296678 - glutathione S-transferase catalyzes the formation of 2%2C4-dinitrophenyl-S-glutathione from 1-chloro-2%2C4-dinitrobenzene and glutathione gene gene3239 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16210 HW43_RS16215 HW43_15745 HW43_RS16215 3296814 3297461 + disulfide-bond oxidoreductase YfcG gene gene3240 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16215 HW43_RS16220 HW43_15750 folX folX 3297518 3297880 + D-erythro-7%2C8-dihydroneopterin triphosphate epimerase catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate gene gene3241 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16220 HW43_RS16225 HW43_15755 HW43_RS16225 3297901 3298794 + epimerase gene gene3242 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16225 HW43_RS16230 HW43_15760 HW43_RS16230 3298842 3299744 - transposase gene gene3243 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16230 HW43_RS16235 HW43_15765 HW43_RS16235 3299941 3300714 - histidine transport ATP-binding protein HisP gene gene3244 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16235 HW43_RS16240 HW43_15770 HW43_RS16240 3300722 3301438 - histidine ABC transporter permease with HisJPQ is involved in transport of histidine%2C lysine%2C arginine and ornithine gene gene3245 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16240 HW43_RS16245 HW43_15775 HW43_RS16245 3301435 3302121 - histidine ABC transporter permease with HisJMP is involved in the transport of histidine/lysine/arginine/ornithine gene gene3246 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16245 HW43_RS16250 HW43_15780 HW43_RS16250 3302211 3302993 - histidine-binding periplasmic protein with HisPMQ is involved in the transport of histidine gene gene3247 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16250 HW43_RS16255 HW43_15785 HW43_RS16255 3303214 3303996 - lysine/arginine/ornithine ABC transporter substrate-binding protein with HisPMQ is involved in the transport of histidine gene gene3248 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16255 HW43_RS16260 HW43_15790 HW43_RS16260 3304262 3304831 - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase partner protein catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate gene gene3249 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16260 HW43_RS16265 HW43_15795 HW43_RS16265 3304926 3306443 - amidophosphoribosyltransferase Catalyzes first step of the de novo purine nucleotide biosynthetic pathway gene gene3250 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16265 HW43_RS16270 HW43_15800 HW43_RS16270 3306480 3306968 - colicin V production protein membrane protein required for colicin V production gene gene3251 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16270 HW43_RS16275 HW43_15805 HW43_RS16275 3307227 3307889 - cell division protein DedD gene gene3252 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16275 HW43_RS16280 HW43_15810 HW43_RS16280 3307879 3309147 - bifunctional folylpolyglutamate synthase/ dihydrofolate synthase gene gene3253 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16280 HW43_RS16285 HW43_15815 HW43_RS16285 3309217 3310131 - acetyl-CoA carboxylase carboxyltransferase subunit beta catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%3B forms a tetramer of AccA2D2 subunits gene gene3254 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16285 HW43_RS16290 HW43_15820 HW43_RS16290 3310287 3310946 - membrane protein gene gene3255 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16290 HW43_RS16295 HW43_15825 truA truA 3311029 3311841 - tRNA pseudouridine synthase A mediates pseudouridylation (positions 38%2C 39%2C 40) at the tRNA anticodon region which contributes to the structural stability gene gene3256 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16295 HW43_RS16300 HW43_15830 HW43_RS16300 3311841 3312854 - semialdehyde dehydrogenase gene gene3257 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16300 HW43_RS16305 HW43_15835 HW43_RS16305 3312920 3314032 - erythronate-4-phosphate dehydrogenase catalyzes the formation of 3-hydroxy-2-oxo-4-phosphonooxybutanoate from erythronate-4-phosphate gene gene3258 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16305 HW43_RS16310 HW43_15840 HW43_RS16310 3314237 3315241 - integrase gene gene3259 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16310 HW43_RS16315 HW43_15845 HW43_RS16315 3315338 3315658 - repressor gene gene3260 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16315 HW43_RS16320 HW43_25470 HW43_RS16320 3315772 3316059 + hypothetical protein gene gene3261 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16320 HW43_RS16325 HW43_15855 HW43_RS16325 3316066 3316272 + membrane protein gene gene3262 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16325 HW43_RS16330 HW43_15865 HW43_RS16330 3316525 3316866 + hypothetical protein gene gene3263 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16330 HW43_RS16335 HW43_15870 HW43_RS16335 3316877 3317164 + hypothetical protein gene gene3264 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16335 HW43_RS16340 HW43_15875 HW43_RS16340 3317176 3317418 + DNA modification methyltransferase gene gene3265 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16340 HW43_RS16345 HW43_15880 HW43_RS16345 3317415 3317528 + hypothetical protein gene gene3266 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16345 HW43_RS16350 HW43_15885 HW43_RS16350 3317615 3317818 + hypothetical protein gene gene3267 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16350 HW43_RS16355 HW43_15890 HW43_RS16355 3317815 3318081 + MarR family transcriptional regulator gene gene3268 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16355 HW43_RS16360 HW43_15895 HW43_RS16360 3318078 3318377 + hypothetical protein gene gene3269 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16360 HW43_RS16365 HW43_15900 HW43_RS16365 3318700 3318891 + derepression protein gene gene3270 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16365 HW43_RS16370 HW43_15905 HW43_RS16370 3319003 3319368 + hypothetical protein gene gene3271 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16370 HW43_RS16375 HW43_15910 HW43_RS16375 3319375 3322182 + replication protein gene gene3272 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16375 HW43_RS16380 HW43_15915 HW43_RS16380 3322259 3323218 + recombinase gene gene3273 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16380 HW43_RS16385 HW43_15920 HW43_RS16385 3323223 3323534 + chromosome partitioning protein gene gene3274 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16385 HW43_RS16390 HW43_15925 HW43_RS16390 3323598 3324188 + hypothetical protein gene gene3275 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16390 HW43_RS16395 HW43_15930 HW43_RS16395 3324679 3325725 - phage portal protein gpQ%3B Q protein%3B structural capsid protein%3B bacteriophage P2-like virions include a head and a tail%3B Q is a connector or portal protein that joins phage head and tail%3B Q%2C P and M proteins are needed to package DNA into proheads and for the conversion of proheads to capsids gene gene3276 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16395 HW43_RS16400 HW43_15935 HW43_RS16400 3325725 3327476 - terminase gene gene3277 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16400 HW43_RS16405 HW43_15940 HW43_RS16405 3327631 3328467 + phage capsid scaffolding protein gene gene3278 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16405 HW43_RS16410 HW43_15945 HW43_RS16410 3328491 3329543 + oxidoreductase gene gene3279 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16410 HW43_RS16415 HW43_15950 HW43_RS16415 3329589 3330389 + terminase gene gene3280 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16415 HW43_RS16420 HW43_15955 HW43_RS16420 3330491 3330985 + phage capsid assembly protein gene gene3281 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16420 HW43_RS16425 HW43_15960 HW43_RS16425 3330985 3331185 + tail protein gene gene3282 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16425 HW43_RS16430 HW43_15965 HW43_RS16430 3331188 3331511 + holin gene gene3283 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16430 HW43_RS16435 HW43_15970 HW43_RS16435 3331566 3332111 + hypothetical protein gene gene3284 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16435 HW43_RS16440 HW43_15975 HW43_RS16440 3332108 3332515 + hypothetical protein gene gene3285 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16440 HW43_RS16445 HW43_15980 HW43_RS16445 3332653 3333120 + tail protein gene gene3286 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16445 HW43_RS16450 HW43_15985 HW43_RS16450 3333113 3333748 + phage tail protein gene gene3287 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16450 HW43_RS16455 HW43_15990 HW43_RS16455 3333745 3334326 + baseplate assembly protein gene gene3288 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16455 HW43_RS16460 HW43_15995 HW43_RS16460 3334323 3334673 + baseplate assembly protein gene gene3289 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16460 HW43_RS16465 HW43_16000 HW43_RS16465 3334677 3335573 + baseplate assembly protein gene gene3290 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16465 HW43_RS16470 HW43_16005 HW43_RS16470 3335566 3336096 + tail protein gene gene3291 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16470 HW43_RS16475 HW43_16010 HW43_RS16475 3336099 3338210 + phage tail protein gene gene3292 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16475 HW43_RS16480 HW43_16015 HW43_RS16480 3338210 3338809 + tail assembly protein gene gene3293 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16480 HW43_RS16485 HW43_16020 HW43_RS16485 3338904 3340082 + hypothetical protein gene gene3294 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16485 HW43_RS16490 HW43_16025 HW43_RS16490 3340179 3340667 - tail protein gene gene3295 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16490 HW43_RS16495 HW43_16030 HW43_RS16495 3340680 3343487 - phage tail tape measure protein gene gene3296 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16495 HW43_RS16500 HW43_16035 HW43_RS16500 3343474 3343602 - tail fiber protein gene gene3297 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16500 HW43_RS16505 HW43_16040 HW43_RS16505 3343638 3344003 - tail protein gene gene3298 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16505 HW43_RS16510 HW43_16045 HW43_RS16510 3344058 3344570 - tail protein gene gene3299 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16510 HW43_RS16515 HW43_16050 HW43_RS16515 3344570 3345754 - tail protein gene gene3300 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16515 HW43_RS16520 HW43_16055 HW43_RS16520 3345912 3347021 + late control protein D gene gene3301 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16520 HW43_RS16525 HW43_16060 HW43_RS16525 3347142 3348164 - hypothetical protein gene gene3302 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16525 HW43_RS16530 HW43_25475 HW43_RS16530 3348356 3348616 + hypothetical protein gene gene3303 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16530 HW43_RS16535 HW43_16070 HW43_RS16535 3348807 3348947 + hypothetical protein gene gene3304 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16535 HW43_RS16540 HW43_16075 HW43_RS16540 3349209 3349541 + hypothetical protein gene gene3305 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16540 HW43_RS16550 HW43_25480 flk flk 3350707 3351701 + flagella biosynthesis regulator in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system%3B lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm%3B inner membrane-anchored protein gene gene3307 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16550 HW43_RS16555 HW43_16090 HW43_RS16555 3351698 3352876 - arabinose efflux transporter gene gene3308 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16555 HW43_RS16560 HW43_16095 HW43_RS16560 3353141 3354361 - 3-oxoacyl-ACP synthase I FabB%2C beta-Ketoacyl-ACP synthase I%2C KASI%3B catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP%3B required for the elongation of short-chain unsaturated acyl-ACP gene gene3309 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16560 HW43_RS16565 HW43_16100 mnmC mnmC 3354520 3356526 + tRNA methyltransferase 5-methylaminomethyl-2-thiouridine-forming enzyme methyltransferase/FAD-dependent demodification enzyme gene gene3310 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16565 HW43_RS16570 HW43_16105 HW43_RS16570 3356647 3356925 - hypothetical protein gene gene3311 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16570 HW43_RS16575 HW43_16110 HW43_RS16575 3356959 3357507 - hypothetical protein gene gene3312 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16575 HW43_RS16580 HW43_16115 HW43_RS16580 3357507 3358316 - membrane protein gene gene3313 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16580 HW43_RS16585 HW43_16120 mepA mepA 3358316 3359140 - penicillin-insensitive murein endopeptidase D-alanyl-D-alanine endopeptidase%3B functions in hydrolyzing cell wall peptidoglycan%3B similar to LAS metallopeptidases%3B forms a dimer in periplasm gene gene3314 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16585 HW43_RS16590 HW43_16125 HW43_RS16590 3359144 3360229 - chorismate synthase catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis gene gene3315 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16590 HW43_RS16595 HW43_16130 HW43_RS16595 3360264 3361196 - N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase involved in methylation of ribosomal protein L3 gene gene3316 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16595 HW43_RS16600 HW43_16135 HW43_RS16600 3361362 3361913 + peptidase S10 gene gene3317 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16600 HW43_RS16605 HW43_16140 HW43_RS16605 3362035 3362892 - fimbrial protein gene gene3318 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16605 HW43_RS16610 HW43_16145 HW43_RS16610 3362894 3363418 - fimbrial protein gene gene3319 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16610 HW43_RS16615 HW43_16150 HW43_RS16615 3363415 3363885 - fimbrial protein SteE gene gene3320 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16615 HW43_RS16620 HW43_16155 HW43_RS16620 3363882 3364388 - fimbrial protein gene gene3321 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16620 HW43_RS16625 HW43_16160 HW43_RS16625 3364405 3365157 - fimbrial protein StfD gene gene3322 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16625 HW43_RS16630 HW43_16165 HW43_RS16630 3365177 3367819 - fimbrial protein SteB gene gene3323 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16630 HW43_RS16635 HW43_16170 HW43_RS16635 3367901 3368464 - fimbrial protein gene gene3324 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16635 HW43_RS16640 HW43_16175 HW43_RS16640 3369139 3369624 - phosphohistidine phosphatase gene gene3325 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16640 HW43_RS16645 HW43_16180 fadJ fadJ 3369827 3371971 - fatty acid oxidation complex subunit alpha multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase%3B catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA%3B exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI%3B similar to FadA2B2 complex%3B involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate gene gene3326 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16645 HW43_RS16650 HW43_16185 fadI fadI 3371971 3373281 - 3-ketoacyl-CoA thiolase FadI%3B fatty acid oxidation complex component beta%3B functions in a heterotetramer with FadJ%3B similar to FadA2B2 complex%3B functions in beta-oxidation of fatty acids during anaerobic growth gene gene3327 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16650 HW43_RS16655 HW43_16190 HW43_RS16655 3373461 3373745 - hypothetical protein gene gene3328 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16655 HW43_RS16660 HW43_16195 HW43_RS16660 3374117 3375457 + long-chain fatty acid outer membrane transporter gene gene3329 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16660 HW43_RS16665 HW43_16200 HW43_RS16665 3375823 3376881 + hypothetical protein gene gene3330 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16665 HW43_RS16670 HW43_16205 HW43_RS16670 3377063 3377818 - lipoprotein involved in maintaining OM lipid asymmetry gene gene3331 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16670 HW43_RS16675 HW43_16210 HW43_RS16675 3378112 3379044 + transporter gene gene3332 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16675 HW43_RS16680 HW43_16215 HW43_RS16680 3379120 3379194 + tRNA-Arg tRNA gene3333 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16680 HW43_RS16685 HW43_16220 HW43_RS16685 3379635 3380882 - MFS transporter gene gene3334 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16685 HW43_RS16690 HW43_16225 HW43_RS16690 3380954 3381868 - aminoimidazole riboside kinase phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P)%3B synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least gene gene3335 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16690 HW43_RS16695 HW43_16230 HW43_RS16695 3382084 3383517 + glycosyl hydrolase family 32 gene gene3336 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16695 HW43_RS16700 HW43_16235 HW43_RS16700 3383525 3384520 - sucrose operon repressor gene gene3337 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16700 HW43_RS16705 HW43_16240 HW43_RS16705 3384763 3384981 + hypothetical protein gene gene3338 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16705 HW43_RS16710 HW43_16245 HW43_RS16710 3384999 3386327 + d-serine dehydratase catalyzes the formation of pyruvate from serine gene gene3339 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16710 HW43_RS16715 HW43_16250 emrB emrB 3386435 3387973 - multidrug resistance protein EmrY multidrug MFS transporte%3B with EmrA is involved in resistance to hydrophobic antibiotics such as nalidixic acid gene gene3340 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16715 HW43_RS16720 HW43_16255 HW43_RS16720 3387973 3389136 - multidrug resistance protein EmrK with ErmA and TolC forms a multidrug efflux system gene gene3341 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16720 HW43_RS16725 HW43_16260 HW43_RS16725 3389551 3390165 + positive transcription regulator EvgA response regulator in two-component regulatory system with EvgS%3B phosphorylated EvgA activates ompC%2C emrKY%2C gadABC%2C hdeAB and others genes%3B involved in acid resistance%2C osmotic adaption%2C and drug resistance gene gene3342 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16725 HW43_RS16730 HW43_16265 HW43_RS16730 3390380 3393763 + sensor histidine kinase gene gene3343 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16730 HW43_RS16735 HW43_16270 HW43_RS16735 3393819 3394964 - acetyl-CoA--oxalate CoA-transferase gene gene3344 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16735 HW43_RS16740 HW43_16275 HW43_RS16740 3395038 3395982 - transporter member of the AEC family of auxin efflux transporters%3B unknown function gene gene3345 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16740 HW43_RS16745 HW43_16280 HW43_RS16745 3396052 3397746 - oxalyl-CoA decarboxylase catalyzes the formation of formyl-CoA from oxalyl-CoA gene gene3346 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16745 HW43_RS16750 HW43_16285 HW43_RS16750 3397800 3399050 - formyl-CoA--oxalate CoA-transferase catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA gene gene3347 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16750 HW43_RS16755 HW43_16290 HW43_RS16755 3399563 3400195 - hypothetical protein gene gene3348 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16755 HW43_RS16760 HW43_16295 HW43_RS16760 3400491 3400766 + lipoprotein gene gene3349 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16760 HW43_RS16765 HW43_25485 HW43_RS16765 3400751 3400888 - hypothetical protein gene gene3350 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16765 HW43_RS16770 HW43_16300 HW43_RS16770 3400843 3401085 - hypothetical protein gene gene3351 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16770 HW43_RS16775 HW43_16305 HW43_RS16775 3401438 3402358 + lipid A biosynthesis palmitoleoyltransferase Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock gene gene3352 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16775 HW43_RS16780 HW43_16310 HW43_RS16780 3402850 3404088 - glutamate--pyruvate aminotransferase AlaC gene gene3353 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16780 HW43_RS16785 HW43_16320 HW43_RS16785 3404465 3406162 + membrane protein gene gene3354 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16785 HW43_RS16790 HW43_16325 HW43_RS16790 3406177 3406911 + two-component system response regulator gene gene3355 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16790 HW43_RS16795 HW43_16330 HW43_RS16795 3406924 3407781 + AraC family transcriptional regulator gene gene3356 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16795 HW43_RS16800 HW43_16335 HW43_RS16800 3407784 3410279 - PTS fructose transporter subunit IIA gene gene3357 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16800 HW43_RS16805 HW43_16340 HW43_RS16805 3410304 3411341 - exoaminopeptidase metalloprotein gene gene3358 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16805 HW43_RS16810 HW43_16345 HW43_RS16810 3411341 3412426 - aminopeptidase Xaa-Pro aminopeptidase%3B limited methionine aminopeptidase gene gene3359 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16810 HW43_RS16815 HW43_16350 HW43_RS16815 3412441 3413688 - PTS fructose transporter subunit IIC gene gene3360 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16815 HW43_RS16820 HW43_16355 HW43_RS16820 3413710 3414036 - PTS fructose transporter subunit IIB gene gene3361 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16820 HW43_RS16825 HW43_16360 glk glk 3414255 3415220 - glucokinase catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate gene gene3362 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16825 HW43_RS16830 HW43_16365 HW43_RS16830 3415424 3416680 + ion channel protein gene gene3363 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16830 HW43_RS16835 HW43_16370 HW43_RS16835 3416795 3417121 + hypothetical protein gene gene3364 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16835 HW43_RS16840 HW43_25490 HW43_RS16840 3417042 3417203 + hypothetical protein gene gene3365 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16840 HW43_RS16845 HW43_16375 HW43_RS16845 3417262 3418500 - divalent metal cation transporter MntH gene gene3366 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16845 HW43_RS16850 HW43_16380 HW43_RS16850 3418836 3420038 + nucleoside permease NupC gene gene3367 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16850 HW43_RS16855 HW43_16385 HW43_RS16855 3420088 3422277 - diguanylate cyclase gene gene3368 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16855 HW43_RS16860 HW43_16390 HW43_RS16860 3422485 3422560 - tRNA-Ala tRNA gene3369 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16860 HW43_RS16865 HW43_16395 HW43_RS16865 3422600 3422675 - tRNA-Ala tRNA gene3370 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16865 HW43_RS16870 HW43_16400 HW43_RS16870 3422911 3423255 + DUF1323 family DNA-binding protein gene gene3371 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16870 HW43_RS16875 HW43_16405 HW43_RS16875 3423257 3423649 + DUF1323 family DNA-binding protein gene gene3372 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16875 HW43_RS16880 HW43_16410 gltX gltX 3423701 3425116 - glutamate--tRNA ligase catalyzes a two-step reaction%2C first charging an glutamate molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B contains discriminating and non-discriminating subtypes gene gene3373 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16880 HW43_RS16885 HW43_16415 HW43_RS16885 3425375 3425450 + tRNA-Val tRNA gene3374 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16885 HW43_RS16890 HW43_16420 HW43_RS16890 3425495 3425570 + tRNA-Val tRNA gene3375 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16890 HW43_RS16895 HW43_16425 HW43_RS16895 3425617 3425692 + tRNA-Val tRNA gene3376 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16895 HW43_RS16900 HW43_16430 HW43_RS16900 3425697 3425772 + tRNA-Lys tRNA gene3377 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16900 HW43_RS16905 HW43_16435 HW43_RS16905 3425881 3426765 - transcriptional regulator gene gene3378 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16905 HW43_RS16910 HW43_25495 HW43_RS16910 3426806 3426964 - hypothetical protein gene gene3379 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16910 HW43_RS16915 HW43_16445 HW43_RS16915 3427017 3428273 - nucleoside permease gene gene3380 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16915 HW43_RS16920 HW43_16450 HW43_RS16920 3428333 3429166 - purine nucleoside phosphorylase gene gene3381 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16920 HW43_RS16925 HW43_16455 HW43_RS16925 3429415 3430179 + membrane protein gene gene3382 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16925 HW43_RS16930 HW43_16460 HW43_RS16930 3430218 3431144 - LysR family transcriptional regulator gene gene3383 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16930 HW43_RS16935 HW43_16465 HW43_RS16935 3431234 3432232 + hypothetical protein gene gene3384 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16935 HW43_RS16940 HW43_16470 HW43_RS16940 3432229 3432447 - DUF3820 domain-containing protein gene gene3385 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16940 HW43_RS16945 HW43_16475 ligA ligA 3432449 3434464 - DNA ligase this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction%3B essential for DNA replication and repair of damaged DNA%3B similar to ligase LigB gene gene3386 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16945 HW43_RS16950 HW43_16480 HW43_RS16950 3434535 3435521 - Cell division protein ZipA homolog interacts with cell division protein FitsZ and may be required to anchor septal ring structure gene gene3387 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16950 HW43_RS16955 HW43_16485 HW43_RS16955 3435751 3436512 + sulfate transporter CysZ gene gene3388 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16955 HW43_RS16960 HW43_16490 HW43_RS16960 3436697 3437668 + cysteine synthase A gene gene3389 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16960 HW43_RS16965 HW43_16495 HW43_RS16965 3438052 3438309 + phosphocarrier protein HPr gene gene3390 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16965 HW43_RS16970 HW43_16500 HW43_RS16970 3438354 3440081 + phosphoenolpyruvate-protein phosphotransferase Phosphotransferase system%2C enzyme I%3B transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein%3B part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active-transport system gene gene3391 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16970 HW43_RS16975 HW43_16505 HW43_RS16975 3440122 3440631 + glucose-specific phosphotransferase enzyme IIA component phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene3392 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16975 HW43_RS16980 HW43_16510 pdxK pdxK 3440673 3441524 - pyridoxine kinase catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal gene gene3393 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16980 HW43_RS16985 HW43_16515 HW43_RS16985 3441629 3441997 + hypothetical protein gene gene3394 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16985 HW43_RS16990 HW43_16520 cysM cysM 3442000 3442911 - cysteine synthase B catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide gene gene3395 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16990 HW43_RS16995 HW43_16525 HW43_RS16995 3443045 3444142 - sulfate ABC transporter ATP-binding protein gene gene3396 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS16995 HW43_RS17000 HW43_16530 cysW cysW 3444132 3445007 - sulfate/thiosulfate transporter permease subunit Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import gene gene3397 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17000 HW43_RS17005 HW43_16535 HW43_RS17005 3445007 3445840 - sulfate ABC transporter permease gene gene3398 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17005 HW43_RS17010 HW43_16540 HW43_RS17010 3445840 3446856 - thiosulfate transporter subunit gene gene3399 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17010 HW43_RS17015 HW43_16545 HW43_RS17015 3447014 3447805 - oxidoreductase UcpA gene gene3400 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17015 HW43_RS17020 HW43_16550 HW43_RS17020 3447934 3448791 - transcriptional regulator repressor for murPQ%3B N-acetylmuramic acid 6-phosphate inducible gene gene3401 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17020 HW43_RS17025 HW43_16555 HW43_RS17025 3448955 3449851 + N-acetylmuramic acid 6-phosphate etherase catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate%3B involved in MurNAc dissimilation pathway gene gene3402 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17025 HW43_RS17030 HW43_16560 murP murP 3449855 3451279 + PTS N-acetylmuramic acid EIIBC component belongs to PEP-dependent PTS system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel%3B requires crr-encoded enzyme IIA-glucose component gene gene3403 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17030 HW43_RS17035 HW43_16565 HW43_RS17035 3451284 3452588 + esterase gene gene3404 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17035 HW43_RS17040 HW43_16570 HW43_RS17040 3452646 3453545 - deferrochelatase/peroxidase gene gene3405 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17040 HW43_RS17045 HW43_16575 HW43_RS17045 3453641 3454216 - RpoE-regulated lipoprotein gene gene3406 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17045 HW43_RS17050 HW43_16580 HW43_RS17050 3454277 3454726 - membrane protein gene gene3407 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17050 HW43_RS17055 HW43_16585 HW43_RS17055 3454713 3455138 - acetyltransferase YpeA gene gene3408 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17055 HW43_RS17060 HW43_16590 HW43_RS17060 3455352 3456221 + N-acetylmuramoyl-L-alanine amidase gene gene3409 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17060 HW43_RS17065 HW43_16595 HW43_RS17065 3456225 3457124 + coproporphyrinogen III oxidase catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis gene gene3410 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17065 HW43_RS17070 HW43_16600 HW43_RS17070 3457130 3458182 - transcriptional regulator activates the transcription of the ethanolamine utilization operon gene gene3411 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17070 HW43_RS17075 HW43_16605 HW43_RS17075 3458228 3458728 - ethanolamine utilization protein EutK ethanolamine utilization protein%3B involved in the degredation of ethanolamine gene gene3412 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17075 HW43_RS17080 HW43_16610 HW43_RS17080 3458741 3459400 - ethanolamine utilization protein EutL carboxysome structural protein involved in ethanolamine utilization gene gene3413 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17080 HW43_RS17085 HW43_16615 HW43_RS17085 3459410 3460297 - ethanolamine ammonia-lyase light chain catalyzes the formation of acetaldehyde from ethanolamine gene gene3414 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17085 HW43_RS17090 HW43_16620 HW43_RS17090 3460318 3461679 - ethanolamine ammonia-lyase heavy chain with EutC catalyzes the formation of acetaldehyde and ammonia from ethanolamine gene gene3415 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17090 HW43_RS17095 HW43_16625 eutA eutA 3461691 3463094 - ethanolamine utilization protein EutA ethanolamine utilization protein EutA gene gene3416 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17095 HW43_RS17100 HW43_16630 HW43_RS17100 3463091 3464317 - ethanolamine utilization protein EutH may be involved in the transport of ethanolamine gene gene3417 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17100 HW43_RS17105 HW43_16635 HW43_RS17105 3464434 3465621 - ethanol dehydrogenase aldehyde reductase%3B catalyzes the conversion of acetaldehyde to ethanol gene gene3418 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17105 HW43_RS17110 HW43_16640 HW43_RS17110 3465611 3466447 - ethanolamine utilization protein EutJ possible chaperonin%3B may be involved in the assembly of the carboxysome gene gene3419 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17110 HW43_RS17115 HW43_16645 HW43_RS17115 3466458 3467861 - aldehyde dehydrogenase ethanolamine utilization protein%3B catalyzes the formation of acetyl-CoA from acetaldehyde gene gene3420 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17115 HW43_RS17120 HW43_16650 HW43_RS17120 3467873 3468160 - ethanolamine utilization protein EutN gene gene3421 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17120 HW43_RS17125 HW43_16655 HW43_RS17125 3468267 3468560 - ethanolamine utilization protein EutM ethanolamine utilization protein%3B involved in the degredation of ethanolamine gene gene3422 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17125 HW43_RS17130 HW43_16660 HW43_RS17130 3468599 3469615 - ethanolamine utilization protein EutD gene gene3423 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17130 HW43_RS17135 HW43_16665 HW43_RS17135 3469612 3470415 - ethanolamine utilization cobalamin adenosyltransferase catalyzes the conversion of cob(I)yrinic acid a%2Cc-diamide to adenosylcob(III)yrinic acid a%2Cc-diamide gene gene3424 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17135 HW43_RS17140 HW43_16670 HW43_RS17140 3470412 3471113 - ethanolamine utilization protein EutQ gene gene3425 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17140 HW43_RS17145 HW43_16675 HW43_RS17145 3471088 3471567 - ethanolamine utilization protein EutP gene gene3426 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17145 HW43_RS17150 HW43_16680 HW43_RS17150 3471580 3471915 - ethanolamine utilization protein EutS ethanolamine utilization protein%3B involved in the degredation of ethanolamine gene gene3427 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17150 HW43_RS17155 HW43_16685 HW43_RS17155 3472208 3474487 - malic enzyme NADP-dependent%3B catalyzes the oxidative decarboxylation of malate to form pyruvate%3B decarboxylates oxaloacetate gene gene3428 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17155 HW43_RS17160 HW43_16690 HW43_RS17160 3474776 3475726 + transaldolase A gene gene3429 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17160 HW43_RS17165 HW43_16695 HW43_RS17165 3475746 3477749 + transketolase catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate%3B can transfer ketol groups between several groups%3B in Escherichia coli there are two tkt genes%2C tktA expressed during exponential growth and the tktB during stationary phase gene gene3430 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17165 HW43_RS17170 HW43_16700 HW43_RS17170 3477825 3478868 - hypothetical protein gene gene3431 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17170 HW43_RS17175 HW43_16705 HW43_RS17175 3478994 3479569 - GDP-mannose pyrophosphatase NudK gene gene3432 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17175 HW43_RS17180 HW43_16710 HW43_RS17180 3479637 3481616 - oxidoreductase Fe-S-binding subunit unknown function%3B in E. coli the aegA gene is regulated by Fnr%2C NarXL%2C and NarQ (but not ArcA)%2C induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) gene gene3433 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17180 HW43_RS17185 HW43_16715 HW43_RS17185 3481822 3483522 + nitrate/nitrite two-component system sensor histidine kinase gene gene3434 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17185 HW43_RS17190 HW43_16720 HW43_RS17190 3483686 3486799 + multidrug efflux RND transporter permease subunit gene gene3435 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17190 HW43_RS17195 HW43_25500 HW43_RS17195 3486886 3487065 + hypothetical protein gene gene3436 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17195 HW43_RS17200 HW43_16725 HW43_RS17200 3487338 3487694 + reductase gene gene3437 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17200 HW43_RS17205 HW43_16730 HW43_RS17205 3487698 3488825 + succinyl-diaminopimelate desuccinylase gene gene3438 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17205 HW43_RS17210 HW43_16735 HW43_RS17210 3488853 3489053 + membrane protein gene gene3439 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17210 HW43_RS17215 HW43_16740 HW43_RS17215 3489134 3489832 - hydrolase gene gene3440 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17215 HW43_RS17220 HW43_16745 HW43_RS17220 3489906 3491921 - methionine tRNA cytidine acetyltransferase cetylates the wobble base C34 of the elongation-specific methionine tRNA gene gene3441 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17220 HW43_RS17225 HW43_16750 HW43_RS17225 3491936 3492799 - hypothetical protein gene gene3442 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17225 HW43_RS17230 HW43_16755 HW43_RS17230 3492946 3493344 - hypothetical protein stability determinant protein gene gene3443 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17230 HW43_RS17235 HW43_16760 HW43_RS17235 3493344 3493571 - antitoxin gene gene3444 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17235 HW43_RS17240 HW43_16765 HW43_RS17240 3493727 3494440 - phosphoribosylaminoimidazole-succinocarboxamide synthase catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis%3B SAICAR synthase gene gene3445 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17240 HW43_RS17245 HW43_25505 HW43_RS17245 3494512 3494742 + hypothetical protein gene gene3446 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17245 HW43_RS17250 HW43_16770 HW43_RS17250 3494653 3495687 - outer membrane protein assembly factor BamC gene gene3447 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17250 HW43_RS17255 HW43_16775 HW43_RS17255 3495704 3496582 - 4-hydroxy-tetrahydrodipicolinate synthase gene gene3448 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17255 HW43_RS17260 HW43_16780 gcvR gcvR 3496728 3497300 + glycine cleavage system transcriptional regulator negative transcriptional regulator of the gcvTHP operon gene gene3449 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17260 HW43_RS17265 HW43_16785 bcp bcp 3497300 3497770 + peroxiredoxin bacterioferritin comigratory protein%3B thiol peroxidase%3B thioredoxin-dependent%3B hydroperoxide peroxidase%3B in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide%3B contains an active site cysteine gene gene3450 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17265 HW43_RS17270 HW43_16790 HW43_RS17270 3498023 3498640 + hydrogenase-4 F-S subunit gene gene3451 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17270 HW43_RS17275 HW43_16795 HW43_RS17275 3498640 3499311 + hypothetical protein gene gene3452 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17275 HW43_RS17280 HW43_16800 HW43_RS17280 3499266 3500657 + hydantoin racemase gene gene3453 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17280 HW43_RS17285 HW43_16805 hycD hycD 3500668 3501615 + hydrogenase 3 membrane subunit formate hydrogenlyase subunit 4%3B HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide gene gene3454 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17285 HW43_RS17290 HW43_16810 HW43_RS17290 3501632 3503071 + hydrogenase-4 component D gene gene3455 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17290 HW43_RS17295 HW43_16815 hyfE hyfE 3503083 3503733 + hydrogenase-4 component E interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide gene gene3456 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17295 HW43_RS17300 HW43_16820 HW43_RS17300 3503738 3505318 + hydrogenase gene gene3457 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17300 HW43_RS17305 HW43_25510 HW43_RS17305 3505308 3505658 + hypothetical protein gene gene3458 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17305 HW43_RS17310 HW43_16830 hycE hycE 3505554 3507023 + hydrogenase 3 large subunit formate hydrogenlyase subunit 5%3B HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide gene gene3459 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17310 HW43_RS17315 HW43_16835 HW43_RS17315 3507033 3507572 + (4Fe-4S)-binding protein electron transfer protein for hydrogenase-3%3B the formate hydrogenlyase complex comprises of a formate dehydrogenase%2C unidentified electron carriers and hydrogenase-3%3B in this non-energy conserving pathway%2C molecular hydrogen and carbodioxide are released from formate gene gene3460 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17315 HW43_RS17320 HW43_16840 HW43_RS17320 3507569 3508327 + formate hydrogenlyase subunit 7 gene gene3461 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17320 HW43_RS17325 HW43_16845 HW43_RS17325 3508320 3508733 + formate hydrogenlyase maturation protein HycH gene gene3462 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17325 HW43_RS17330 HW43_16850 HW43_RS17330 3508763 3510775 + hydrogenase gene gene3463 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17330 HW43_RS17335 HW43_16855 HW43_RS17335 3510797 3511528 + formate transporter gene gene3464 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17335 HW43_RS17340 HW43_16860 HW43_RS17340 3511682 3512743 - permease gene gene3465 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17340 HW43_RS17345 HW43_16865 HW43_RS17345 3512956 3514419 + beta-barrel assembly-enhancing protease gene gene3466 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17345 HW43_RS17350 HW43_16870 HW43_RS17350 3514440 3514799 + arsenate reductase gene gene3467 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17350 HW43_RS17355 HW43_16875 HW43_RS17355 3514937 3515614 - DnaA regulatory inactivator Hda controls initiation of DNA replication by inhibiting re-initiation of replication%2C promotes hydrolysis of DnaA-bound ATP gene gene3468 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17355 HW43_RS17360 HW43_16880 HW43_RS17360 3515733 3517022 - uracil permease gene gene3469 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17360 HW43_RS17365 HW43_16885 upp upp 3517108 3517734 - uracil phosphoribosyltransferase Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate gene gene3470 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17365 HW43_RS17370 HW43_16890 HW43_RS17370 3518059 3519096 + phosphoribosylformylglycinamidine cyclo-ligase catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis gene gene3471 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17370 HW43_RS17375 HW43_16895 purN purN 3519096 3519734 + phosphoribosylglycinamide formyltransferase glycinamide ribonucleotide transformylase%3B GAR Tfase%3B catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate%3B PurN requires formyl folate for the reaction unlike PurT which uses formate gene gene3472 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17375 HW43_RS17380 HW43_16900 HW43_RS17380 3519905 3521971 + polyphosphate kinase gene gene3473 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17380 HW43_RS17385 HW43_16905 HW43_RS17385 3521976 3523517 + exopolyphosphatase gene gene3474 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17385 HW43_RS17390 HW43_16910 HW43_RS17390 3523556 3525799 - cyclic di-GMP phosphodiesterase gene gene3475 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17390 HW43_RS17395 HW43_25515 HW43_RS17395 3525981 3526133 - hypothetical protein gene gene3476 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17395 HW43_RS17400 HW43_16920 HW43_RS17400 3526151 3526342 + hypothetical protein gene gene3477 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17400 HW43_RS17405 HW43_16925 HW43_RS17405 3526656 3527171 + membrane protein gene gene3478 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17405 HW43_RS17410 HW43_16930 HW43_RS17410 3527187 3527726 + nalidixic acid resistance protein gene gene3479 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17410 HW43_RS17415 HW43_16935 guaA guaA 3527821 3529398 - GMP synthase [glutamine-hydrolyzing] contains glutamine-hydrolyzing domain and glutamine amidotransferase%3B GMP-binding domain%3B functions to produce GMP from XMP in the IMP pathway gene gene3480 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17415 HW43_RS17420 HW43_16940 HW43_RS17420 3529467 3530933 - inosine-5-monophosphate dehydrogenase gene gene3481 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17420 HW43_RS17425 HW43_16945 xseA xseA 3531095 3532465 + exodeoxyribonuclease VII large subunit bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides gene gene3482 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17425 HW43_RS17430 HW43_16950 HW43_RS17430 3532462 3532677 - hypothetical protein gene gene3483 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17430 HW43_RS17435 HW43_16955 HW43_RS17435 3532746 3534218 - GTPase Der gene gene3484 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17435 HW43_RS17440 HW43_16960 HW43_RS17440 3534336 3535514 - outer membrane biogenesis protein BamB gene gene3485 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17440 HW43_RS17445 HW43_16965 HW43_RS17445 3535525 3536145 - membrane protein gene gene3486 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17445 HW43_RS17450 HW43_16970 hisS hisS 3536163 3537437 - histidyl-tRNA synthetase catalyzes a two-step reaction%2C first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B class II aminoacyl-tRNA synthetase%3B forms homodimers%3B some organisms have a paralogous gene%2C hisZ%2C that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG gene gene3487 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17450 HW43_RS17455 HW43_16975 HW43_RS17455 3537548 3538666 - 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin) gene gene3488 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17455 HW43_RS17460 HW43_16980 HW43_RS17460 3538693 3539706 - cytoskeleton protein RodZ gene gene3489 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17460 HW43_RS17465 HW43_16985 HW43_RS17465 3539991 3541145 - 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN 23S rRNA m2A2503 methyltransferase%3B methylates the C2 position of the A2530 nucleotide in 23S rRNA%3B may be involved in antibiotic resistance gene gene3490 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17465 HW43_RS17470 HW43_16990 HW43_RS17470 3541295 3541726 - nucleoside diphosphate kinase catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate gene gene3491 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17470 HW43_RS17475 HW43_16995 HW43_RS17475 3541875 3544187 - penicillin-binding protein 1C penicillin-insensitive transglycosylase/transpeptidase gene gene3492 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17475 HW43_RS17480 HW43_17000 HW43_RS17480 3544188 3549149 - hypothetical protein gene gene3493 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17480 HW43_RS17485 HW43_17005 sseA sseA 3549356 3550201 + 3-mercaptopyruvate sulfurtransferase catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds gene gene3494 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17485 HW43_RS17490 HW43_17010 HW43_RS17490 3550694 3551470 - sseB protein enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I gene gene3495 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17490 HW43_RS17495 HW43_17015 HW43_RS17495 3551612 3552895 - peptidase B catalyzes the removal of an N-terminal amino acid from a peptide or arylamide gene gene3496 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17495 HW43_RS17500 HW43_17020 HW43_RS17500 3553073 3553273 - protein IscX gene gene3497 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17500 HW43_RS17505 HW43_17025 HW43_RS17505 3553285 3553620 - (2Fe-2S) ferredoxin gene gene3498 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17505 HW43_RS17510 HW43_17030 hscA hscA 3553622 3555472 - chaperone protein HscA involved in the maturation of iron-sulfur cluster-containing proteins gene gene3499 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17510 HW43_RS17515 HW43_17035 hscB hscB 3555489 3556004 - co-chaperone protein HscB J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone%3B may function in biogenesis of iron-sulfur proteins gene gene3500 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17515 HW43_RS17520 HW43_17040 iscA iscA 3556100 3556423 - iron-binding protein forms iron-sulfur clusters of ferredoxin [2FE-2S]%3B binds iron in the presence of the thioredoxin reductase system%3B forms homodimers and tetramers%3B similar to SufA protein gene gene3501 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17520 HW43_RS17525 HW43_17045 HW43_RS17525 3556440 3556826 - Fe-S cluster assembly scaffold IscU gene gene3502 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17525 HW43_RS17530 HW43_17050 HW43_RS17530 3556854 3558068 - cysteine desulfurase IscS catalyzes the removal of elemental sulfur from cysteine to produce alanine%3B involved in NAD biosynthesis gene gene3503 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17530 HW43_RS17535 HW43_17055 HW43_RS17535 3558180 3558668 - Fe-S cluster assembly transcriptional regulator IscR regulates the expression of the iscRSUA operon gene gene3504 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17535 HW43_RS17540 HW43_17060 HW43_RS17540 3558938 3559678 - tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ catalyzes the fromation of 2'O-methylated cytidine or 2'O-methylated uridine at position 32 in tRNA gene gene3505 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17540 HW43_RS17545 HW43_17065 HW43_RS17545 3559797 3560600 + inositol-1-monophosphatase gene gene3506 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17545 HW43_RS17550 HW43_17070 HW43_RS17550 3560745 3561599 + S9 family prolyl oligopeptidase gene gene3507 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17550 HW43_RS17555 HW43_17075 HW43_RS17555 3561790 3563070 + stationary phase-inducible protein CsiE gene gene3508 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17555 HW43_RS17560 HW43_17080 HW43_RS17560 3563062 3564201 - 3-phenylpropionic acid transporter transporter of 3-phenylpropionate across the inner membrane%3B member of the major facilitator superfamily of transporters gene gene3509 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17560 HW43_RS17565 HW43_17085 HW43_RS17565 3564361 3565251 - LysR family transcriptional regulator activator of 3-phenylpropionic acid catabolism gene gene3510 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17565 HW43_RS17570 HW43_17090 HW43_RS17570 3565387 3566748 + 3-phenylpropionate/cinnamic acid dioxygenase subunit alpha gene gene3511 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17570 HW43_RS17575 HW43_17095 HW43_RS17575 3566745 3567263 + 3-phenylpropionate/cinnamic acid dioxygenase subunit beta gene gene3512 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17575 HW43_RS17580 HW43_17100 HW43_RS17580 3567263 3567583 + 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin subunit gene gene3513 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17580 HW43_RS17585 HW43_17105 HW43_RS17585 3567580 3568392 + 3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenase Converts cis-3-(3-carboxyethyl)-3%2C5-cyclohexadiene-1%2C2-diol (PP-dihydrodiol) into 3-(2%2C3-dihydroxylphenyl)propionate gene gene3514 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17585 HW43_RS17590 HW43_17110 HW43_RS17590 3568402 3569604 + 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin--NAD+ reductase component gene gene3515 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17590 HW43_RS17595 HW43_17115 HW43_RS17595 3569701 3570123 + hypothetical protein gene gene3516 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17595 HW43_RS17600 HW43_17120 HW43_RS17600 3570171 3571043 - hypothetical protein gene gene3517 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17600 HW43_RS17605 HW43_17125 HW43_RS17605 3571055 3572116 - alcohol dehydrogenase gene gene3518 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17605 HW43_RS17610 HW43_17130 HW43_RS17610 3572182 3573180 - ABC transporter permease gene gene3519 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17610 HW43_RS17615 HW43_17135 HW43_RS17615 3573205 3574716 - heme ABC transporter ATP-binding protein gene gene3520 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17615 HW43_RS17620 HW43_17140 HW43_RS17620 3574739 3575722 - sugar ABC transporter substrate-binding protein gene gene3521 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17620 HW43_RS17625 HW43_17145 HW43_RS17625 3575819 3579100 - tetratricopeptide repeat family protein gene gene3522 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17625 HW43_RS17630 HW43_17150 HW43_RS17630 3579218 3580411 + hypothetical protein gene gene3523 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17630 HW43_RS17635 HW43_17155 HW43_RS17635 3580475 3581728 - serine hydroxymethyltransferase gene gene3524 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17635 HW43_RS17640 HW43_17160 HW43_RS17640 3582056 3583246 + flavohemoprotein flavohemoprotein%3B catalyzes the formation of nitrate from nitric oxide%3B can also catalyze the reduction of dihydropteridine gene gene3525 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17640 HW43_RS17645 HW43_17165 HW43_RS17645 3583291 3583629 - nitrogen regulatory protein P-II 1 indirectly regulates nitrogen metabolism%3B at high nitrogen levels P-II prevents the phosphorylation of NR-I%2C the transcriptional activator of the glutamine synthetase gene (glnA)%3B at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA gene gene3526 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17645 HW43_RS17650 HW43_17170 HW43_RS17650 3583690 3585024 - transcriptional regulator with GlrK is part of a two-component signal transduction system regulating glmY gene gene3527 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17650 HW43_RS17655 HW43_17175 HW43_RS17655 3585014 3585727 - membrane protein gene gene3528 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17655 HW43_RS17660 HW43_17180 HW43_RS17660 3585892 3587319 - two-component system sensor histidine kinase part of the GlrKR two-component signal transduction system involved in the regulation of glmY gene gene3529 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17660 HW43_RS17665 HW43_17185 HW43_RS17665 3587895 3591782 - phosphoribosylformylglycinamidine synthase catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis gene gene3530 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17665 HW43_RS17670 HW43_17190 HW43_RS17670 3592040 3593596 + murein transglycosylase gene gene3531 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17670 HW43_RS17675 HW43_17195 HW43_RS17675 3593593 3594096 - adenosine deaminase gene gene3532 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17675 HW43_RS17680 HW43_17200 HW43_RS17680 3594154 3594789 - phosphatidylglycerophosphatase C gene gene3533 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17680 HW43_RS17685 HW43_17205 HW43_RS17685 3594998 3595846 + transcriptional regulator gene gene3534 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17685 HW43_RS17690 HW43_17210 HW43_RS17690 3595902 3596162 + 4Fe-4S binding protein gene gene3535 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17690 HW43_RS17695 HW43_17215 HW43_RS17695 3596356 3596436 - small toxic protein ShoB gene gene3536 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17695 HW43_RS17700 HW43_25520 HW43_RS17700 3596433 3596585 - hypothetical protein gene gene3537 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17700 HW43_RS17705 HW43_25525 HW43_RS17705 3596622 3596750 + glutamate decarboxylase gene gene3538 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17705 HW43_RS17710 HW43_17220 acpS acpS 3596856 3597236 - holo-ACP synthase Catalyzes the formation of holo-ACP%2C which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids gene gene3539 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17710 HW43_RS17715 HW43_17225 HW43_RS17715 3597236 3597967 - pyridoxine 5'-phosphate synthase involved in the de novo synthesis of pyridoxine (Vitamin B6) gene gene3540 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17715 HW43_RS17720 HW43_17230 recO recO 3597979 3598707 - DNA repair protein RecO involved in DNA repair and RecFOR pathway recombination%3B RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA gene gene3541 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17720 HW43_RS17725 HW43_17235 HW43_RS17725 3598719 3599624 - GTPase Era gene gene3542 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17725 HW43_RS17730 HW43_17240 rnc rnc 3599621 3600301 - ribonuclease 3 cytoplasmic enzyme involved in processing rRNA and some mRNAs%3B substrates typically have dsRNA regions%3B forms a homodimer%3B have N-terminal nuclease and C-terminal RNA-binding domains%3B requires magnesium as preferred ion for activity gene gene3543 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17730 HW43_RS17735 HW43_17245 HW43_RS17735 3600574 3601548 - signal peptidase I catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins gene gene3544 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17735 HW43_RS17740 HW43_17250 HW43_RS17740 3601564 3603363 - elongation factor 4 gene gene3545 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17740 HW43_RS17745 HW43_17255 HW43_RS17745 3603561 3604040 - SoxR reducing system protein RseC involved in the reduction of the SoxR iron-sulfur cluster gene gene3546 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17745 HW43_RS17750 HW43_17260 rseB rseB 3604037 3604993 - sigma-E factor regulatory protein RseB periplasmic protein%3B interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP gene gene3547 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17750 HW43_RS17755 HW43_17265 HW43_RS17755 3604993 3605643 - anti-RNA polymerase sigma factor SigE gene gene3548 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17755 HW43_RS17760 HW43_17270 HW43_RS17760 3605676 3606251 - ECF RNA polymerase sigma-E factor Member of the extracytoplasmic function sigma factors which are active under specific conditions%3B binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription%3B this sigma factor is involved in heat shock and oxidative stress response gene gene3549 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17760 HW43_RS17765 HW43_25530 HW43_RS17765 3606248 3606403 - hypothetical protein gene gene3550 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17765 HW43_RS17770 HW43_17275 HW43_RS17770 3606659 3608281 + L-aspartate oxidase catalyzes the formation of oxaloacetate from L-aspartate gene gene3551 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17770 HW43_RS17775 HW43_17280 HW43_RS17775 3608266 3609003 - tRNA1(Val) (adenine(37)-N6)-methyltransferase gene gene3552 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17775 HW43_RS17780 HW43_17285 HW43_RS17780 3609135 3610469 + ATP-dependent RNA helicase SrmB facilitates an early step in the assembly of the 50S subunit of the ribosome gene gene3553 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17780 HW43_RS17785 HW43_25535 HW43_RS17785 3610475 3610627 + hypothetical protein gene gene3554 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17785 HW43_RS17790 HW43_17290 HW43_RS17790 3610678 3611559 - LysR family transcriptional regulator gene gene3555 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17790 HW43_RS17795 HW43_17295 HW43_RS17795 3611662 3612249 + cysteine/O-acetylserine efflux protein gene gene3556 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17795 HW43_RS17800 HW43_17300 HW43_RS17800 3612305 3612688 - autonomous glycyl radical cofactor GrcA stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit gene gene3557 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17800 HW43_RS17805 HW43_17305 HW43_RS17805 3612993 3613682 + uracil-DNA glycosylase Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine gene gene3558 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17805 HW43_RS17810 HW43_17310 HW43_RS17810 3613730 3614767 - methyltransferase gene gene3559 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17810 HW43_RS17815 HW43_25540 HW43_RS17815 3614757 3614915 - hypothetical protein gene gene3560 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17815 HW43_RS17820 HW43_17315 HW43_RS17820 3614974 3615393 + thioredoxin gene gene3561 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17820 HW43_RS17825 HW43_17320 HW43_RS17825 3615462 3616160 + hypothetical protein gene gene3562 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17825 HW43_RS17830 HW43_17325 HW43_RS17830 3616192 3618852 + protein lysine acetyltransferase catalyzes the acetylation of lysine gene gene3563 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17830 HW43_RS17835 HW43_17330 pssA pssA 3618966 3620321 + CDP-diacylglycerol--serine O-phosphatidyltransferase catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine%3B bounds to the ribosome gene gene3564 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17835 HW43_RS17840 HW43_17335 HW43_RS17840 3620418 3620690 + lipoprotein gene gene3565 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17840 HW43_RS17845 HW43_17340 HW43_RS17845 3620687 3621985 - alpha-ketoglutarate transporter gene gene3566 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17845 HW43_RS17850 HW43_RS17850 HW43_RS17850 3621967 3622080 - alpha-ketoglutarate permease gene gene3567 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17850 HW43_RS17855 HW43_17350 HW43_RS17855 3622311 3622426 - 5S ribosomal RNA rRNA gene3568 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17855 HW43_RS17860 HW43_17355 HW43_RS17860 3622503 3625433 - 23S ribosomal RNA rRNA gene3569 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17860 HW43_RS17865 HW43_17360 HW43_RS17865 3625618 3625693 - tRNA-Glu tRNA gene3570 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17865 HW43_RS17870 HW43_17365 HW43_RS17870 3625853 3627408 - 16S ribosomal RNA rRNA gene3571 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17870 HW43_RS17875 HW43_17370 HW43_RS17875 3627850 3630423 - chaperone protein ClpB gene gene3572 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17875 HW43_RS17880 HW43_17375 HW43_RS17880 3630553 3631284 - hypothetical protein gene gene3573 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17880 HW43_RS17885 HW43_17380 rluD rluD 3631281 3632261 - 23S rRNA pseudouridine synthase D responsible for synthesis of pseudouridine from uracil at positions 1911%2C 1915 and 1917 in 23S ribosomal RNA gene gene3574 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17885 HW43_RS17890 HW43_17385 HW43_RS17890 3632396 3633133 + outer membrane protein assembly factor BamD gene gene3575 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17890 HW43_RS17895 HW43_25545 HW43_RS17895 3633163 3633369 + hypothetical protein gene gene3576 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17895 HW43_RS17900 HW43_17390 HW43_RS17900 3633404 3633745 + ribosome-associated inhibitor A associated with 30S ribosomal subunit%3B interferes with translation elongation gene gene3577 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17900 HW43_RS17905 HW43_17395 pheA pheA 3633995 3635155 + bifunctional chorismate mutase/prephenate dehydratase catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis gene gene3578 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17905 HW43_RS17910 HW43_17400 tyrA tyrA 3635198 3636319 - chorismate mutase catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis gene gene3579 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17910 HW43_RS17915 HW43_17405 HW43_RS17915 3636330 3637400 - phospho-2-dehydro-3-deoxyheptonate aldolase catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate%2C tyrosine sensitive gene gene3580 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17915 HW43_RS17920 HW43_17410 HW43_RS17920 3637610 3637975 + lipoprotein gene gene3581 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17920 HW43_RS17925 HW43_17415 HW43_RS17925 3638125 3638643 + hypothetical protein gene gene3582 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17925 HW43_RS17930 HW43_17420 HW43_RS17930 3638636 3639859 + diguanylate cyclase gene gene3583 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17930 HW43_RS17935 HW43_17425 HW43_RS17935 3639875 3640357 + membrane protein gene gene3584 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17935 HW43_RS17940 HW43_17430 HW43_RS17940 3640434 3640781 - 50S ribosomal protein L19 gene gene3585 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17940 HW43_RS17945 HW43_17435 trmD trmD 3640823 3641590 - tRNA (guanine-N(1)-)-methyltransferase methylates guanosine-37 in various tRNAs%3B uses S-adenosyl-L-methionine to transfer methyl group to tRNA gene gene3586 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17945 HW43_RS17950 HW43_17440 rimM rimM 3641621 3642169 - ribosome maturation factor RimM Essential for efficient processing of 16S rRNA gene gene3587 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17950 HW43_RS17955 HW43_17445 HW43_RS17955 3642188 3642436 - 30S ribosomal protein S16 gene gene3588 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17955 HW43_RS17960 HW43_17450 HW43_RS17960 3642573 3643934 - signal recognition particle protein gene gene3589 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17960 HW43_RS17965 HW43_17455 HW43_RS17965 3644101 3644892 + hypothetical protein gene gene3590 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17965 HW43_RS17970 HW43_17460 HW43_RS17970 3644958 3646199 + membrane protein gene gene3591 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17970 HW43_RS17975 HW43_17465 HW43_RS17975 3646322 3646927 + hypothetical protein gene gene3592 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17975 HW43_RS17980 HW43_17470 HW43_RS17980 3646962 3647552 - protein GrpE with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins%3B may act as a thermosensor gene gene3593 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17980 HW43_RS17985 HW43_17475 ppnK ppnK 3647675 3648553 + NAD kinase catalyzes the phosphorylation of NAD to NADP gene gene3594 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17985 HW43_RS17990 HW43_17480 HW43_RS17990 3648639 3650300 + DNA repair protein RecN gene gene3595 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17990 HW43_RS17995 HW43_17485 HW43_RS17995 3650449 3650790 + outer membrane protein assembly factor BamE gene gene3596 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS17995 HW43_RS18000 HW43_17490 HW43_RS18000 3650852 3651142 - hypothetical protein gene gene3597 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18000 HW43_RS18005 HW43_17495 HW43_RS18005 3651132 3651608 - hypothetical protein gene gene3598 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18005 HW43_RS18010 HW43_17500 smpB smpB 3651740 3652222 + SsrA-binding protein binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes%3B also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site%3B SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus%3B both the tmRNA and SmpB are regulated in cell cycle-dependent manner%3B functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation gene gene3599 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18010 HW43_RS18015 HW43_17510 HW43_RS18015 3652965 3654194 + integrase gene gene3600 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18015 HW43_RS18020 HW43_17515 HW43_RS18020 3654233 3654649 + hypothetical protein gene gene3601 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18020 HW43_RS18025 HW43_17520 HW43_RS18025 3654721 3656469 - hypothetical protein gene gene3602 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18025 HW43_RS18030 HW43_17525 HW43_RS18030 3656471 3658189 - histidine kinase gene gene3603 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18030 HW43_RS18035 HW43_34120 HW43_RS18035 3658341 3659207 - transposase gene gene3604 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18035 HW43_RS18040 HW43_34125 HW43_RS18040 3659204 3659503 - transposase gene gene3605 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18040 HW43_RS18045 HW43_17540 HW43_RS18045 3659633 3660265 + alpha-amylase gene gene3606 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18045 HW43_RS18050 HW43_25550 HW43_RS18050 3660404 3660676 + alpha-amylase gene gene3607 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18050 HW43_RS18055 HW43_17545 HW43_RS18055 3661012 3661989 + carbon starvation induced protein in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP%3B the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases%3B forms homotetramers in solution gene gene3608 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18055 HW43_RS18060 HW43_17550 HW43_RS18060 3662009 3663277 + hydroxyglutarate oxidase catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate gene gene3609 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18060 HW43_RS18065 HW43_17555 gabD gabD 3663300 3664748 + succinate-semialdehyde dehydrogenase catalyzes the formation of succinate from succinate semialdehyde%3B NADP dependent gene gene3610 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18065 HW43_RS18070 HW43_17560 HW43_RS18070 3664762 3666042 + 4-aminobutyrate aminotransferase gene gene3611 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18070 HW43_RS18075 HW43_17565 HW43_RS18075 3666280 3667680 + GABA permease gene gene3612 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18075 HW43_RS18080 HW43_17570 HW43_RS18080 3667701 3668363 + transcriptional regulator regulator of gab gene expression gene gene3613 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18080 HW43_RS18085 HW43_17575 HW43_RS18085 3668364 3668813 - peptidoglycan-binding protein LysM gene gene3614 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18085 HW43_RS18090 HW43_25555 HW43_RS18090 3668897 3669055 - hypothetical protein gene gene3615 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18090 HW43_RS18095 HW43_17585 HW43_RS18095 3669238 3669537 + transcriptional regulator gene gene3616 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18095 HW43_RS18100 HW43_17590 HW43_RS18100 3669547 3670071 + membrane protein gene gene3617 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18100 HW43_RS18105 HW43_17595 HW43_RS18105 3670118 3670522 - DNA-binding protein StpA gene gene3618 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18105 HW43_RS18110 HW43_17600 HW43_RS18110 3671190 3671639 + L-alanine exporter AlaE gene gene3619 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18110 HW43_RS18115 HW43_17605 HW43_RS18115 3671676 3672020 - hypothetical protein gene gene3620 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18115 HW43_RS18120 HW43_17610 HW43_RS18120 3672172 3672501 + DUF883 domain-containing protein gene gene3621 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18120 HW43_RS18125 HW43_17615 HW43_RS18125 3672749 3672994 + glutaredoxin gene gene3622 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18125 HW43_RS18130 HW43_17620 nrdI nrdI 3672991 3673401 + protein NrdI in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF gene gene3623 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18130 HW43_RS18135 HW43_17625 HW43_RS18135 3673374 3675518 + ribonucleotide-diphosphate reductase subunit alpha gene gene3624 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18135 HW43_RS18140 HW43_17630 HW43_RS18140 3675528 3676487 + ribonucleoside-diphosphate reductase 2 subunit beta B2 or R2 protein%3B type 1b enzyme%3B catalyzes the rate-limiting step in dNTP synthesis%3B converts nucleotides to deoxynucleotides%3B forms a homodimer and then a multimeric complex with NrdE gene gene3625 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18140 HW43_RS18145 HW43_17635 HW43_RS18145 3676842 3678044 + glycine/betaine ABC transporter ATP-binding protein with ProWX is involved in the high-affinity uptake of glycine betaine gene gene3626 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18145 HW43_RS18150 HW43_17640 HW43_RS18150 3678037 3679101 + glycine/betaine ABC transporter permease with ProVX is involved in the high-affinity uptake of glycine betaine gene gene3627 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18150 HW43_RS18155 HW43_17645 proX proX 3679159 3680151 + glycine/betaine ABC transporter substrate-binding protein with ProVW%2C part of the high-affinity transport system for the osmoprotectant glycine betaine gene gene3628 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18155 HW43_RS18160 HW43_17650 HW43_RS18160 3680343 3681527 + transporter gene gene3629 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18160 HW43_RS18165 HW43_17655 HW43_RS18165 3681651 3682388 + hypothetical protein gene gene3630 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18165 HW43_RS18170 HW43_17660 HW43_RS18170 3682378 3682713 + L-valine exporter%2C norvaline resistance protein gene gene3631 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18170 HW43_RS18175 HW43_17665 HW43_RS18175 3682804 3683334 + transcriptional regulator DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux%3B negative regulator of the multidrug operon emrAB gene gene3632 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18175 HW43_RS18180 HW43_17670 HW43_RS18180 3683461 3684633 + multidrug export protein EmrA with ErmA and TolC forms a multidrug efflux system gene gene3633 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18180 HW43_RS18185 HW43_17675 emrB emrB 3684650 3686188 + multidrug effux MFS transporter subunit EmrB multidrug MFS transporte%3B with EmrA is involved in resistance to hydrophobic antibiotics such as nalidixic acid gene gene3634 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18185 HW43_RS18190 HW43_17680 HW43_RS18190 3686252 3686767 - S-ribosylhomocysteine lyase catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 gene gene3635 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18190 HW43_RS18195 HW43_17685 HW43_RS18195 3686917 3688473 - glutamate--cysteine ligase involved in the first step of glutathione biosynthesis gene gene3636 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18195 HW43_RS18200 HW43_17690 HW43_RS18200 3688546 3688974 - membrane protein gene gene3637 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18200 HW43_RS18205 HW43_17695 HW43_RS18205 3688971 3689537 - fructose-1-P/6-phosphogluconate phosphatase YqaB%3B catalyzes the dephosphorylation of fructose 1-phosphate%2C 6-phosphogluconate and p-nitrophenyl phosphate (pNPP)%3B presents beta-phosphoglucomutase activity at a lower extent gene gene3638 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18205 HW43_RS18210 HW43_17700 HW43_RS18210 3689818 3689894 - tRNA-Arg tRNA gene3639 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18210 HW43_RS18215 HW43_17705 HW43_RS18215 3690093 3690169 - tRNA-Arg tRNA gene3640 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18215 HW43_RS18220 HW43_17710 HW43_RS18220 3690233 3690309 - tRNA-Arg tRNA gene3641 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18220 HW43_RS18225 HW43_17715 HW43_RS18225 3690507 3690583 - tRNA-Arg tRNA gene3642 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18225 HW43_RS18230 HW43_17720 HW43_RS18230 3690587 3690679 - tRNA-Ser tRNA gene3643 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18230 HW43_RS18235 HW43_17725 HW43_RS18235 3690995 3691180 - pleiotropic regulatory protein for carbon source metabolism affects carbohydrate metabolism%3B has regulatory role in many processes gene gene3644 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18235 HW43_RS18240 HW43_17730 HW43_RS18240 3691415 3694045 - alanine--tRNA ligase gene gene3645 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18240 HW43_RS18245 HW43_25560 HW43_RS18245 3693983 3694132 + hypothetical protein gene gene3646 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18245 HW43_RS18250 HW43_17735 recX recX 3694173 3694673 - regulatory protein RecX binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities gene gene3647 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18250 HW43_RS18255 HW43_17740 recA recA 3694916 3695977 - protein RecA catalyzes the hydrolysis of ATP in the presence of single-stranded DNA%2C the ATP-dependent uptake of single-stranded DNA by duplex DNA%2C and the ATP-dependent hybridization of homologous single-stranded DNAs gene gene3648 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18255 HW43_RS18260 HW43_17745 HW43_RS18260 3696057 3696554 - nicotinamide-nucleotide amidohydrolase PncC gene gene3649 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18260 HW43_RS18265 HW43_17750 HW43_RS18265 3696699 3697784 - murein transglycosylase membrane-bound lytic murein transglycosylase B%3B catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan gene gene3650 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18265 HW43_RS18270 HW43_17755 srlA srlA 3698040 3698603 + glucitol/sorbitol permease IIC component catalyzes the phosphorylation of incoming sugar substrates along with their translocation across the cell membrane%3B the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site gene gene3651 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18270 HW43_RS18275 HW43_17760 srlE srlE 3698600 3699559 + PTS sorbitol transporter subunit IIB catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B subunit IIB transfers the phosphoryl group to the substrate gene gene3652 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18275 HW43_RS18280 HW43_17765 HW43_RS18280 3699570 3699941 + PTS sorbitol transporter subunit IIA phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene3653 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18280 HW43_RS18285 HW43_17770 HW43_RS18285 3699945 3700724 + sorbitol-6-phosphate dehydrogenase catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate gene gene3654 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18285 HW43_RS18290 HW43_17775 HW43_RS18290 3700829 3701188 + glucitol operon activator protein regulator for glucitol utilization gene gene3655 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18290 HW43_RS18295 HW43_17780 srlR srlR 3701255 3702028 + glucitol operon repressor regulates genes involved in glucitol utilization gene gene3656 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18295 HW43_RS18300 HW43_17785 HW43_RS18300 3702021 3702986 + arabinose 5-phosphate isomerase GutQ gene gene3657 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18300 HW43_RS18305 HW43_17790 HW43_RS18305 3702983 3704497 - NorR family transcriptional regulator Required for the expression of anaerobic nitric oxide (NO) reductase%3B acts as a transcriptional activator for the norVW operon gene gene3658 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18305 HW43_RS18310 HW43_17795 HW43_RS18310 3704684 3706123 + nitric oxide reductase detoxifies nitric oxide using NADH gene gene3659 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18310 HW43_RS18315 HW43_17800 HW43_RS18315 3706120 3707253 + NADH:flavorubredoxin oxidoreductase gene gene3660 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18315 HW43_RS18320 HW43_17805 HW43_RS18320 3707479 3709731 - carbamoyl phosphate phosphatase carbamoyltransferase%3B involved in the formation of the cyanate group of hydrogenase%3B catalyzes the formation of carbamoyladenylate from carbamoylphosphate and then transfers the carbamoyl group to HypE gene gene3661 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18320 HW43_RS18325 HW43_17810 HW43_RS18325 3709884 3710411 - electron transporter HydN involved in electron transport from formate to hydrogen gene gene3662 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18325 HW43_RS18330 HW43_17815 HW43_RS18330 3710560 3711570 - transcriptional regulator gene gene3663 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18330 HW43_RS18335 HW43_17820 HW43_RS18335 3711830 3713287 + PTS cellobiose transporter subunit IIBC phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel gene gene3664 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18335 HW43_RS18340 HW43_17825 HW43_RS18340 3713296 3714720 + 6-phospho-beta-glucosidase AscB gene gene3665 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18340 HW43_RS18345 HW43_17830 hycI hycI 3714879 3715349 - hydrogenase 3 maturation protease involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE gene gene3666 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18345 HW43_RS18350 HW43_17835 HW43_RS18350 3715342 3715752 - formate hydrogenlyase maturation protein HycH required for the maturation of the formate hydrogenlyase complex gene gene3667 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18350 HW43_RS18355 HW43_17840 HW43_RS18355 3715749 3716516 - formate hydrogenlyase subunit 7 gene gene3668 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18355 HW43_RS18360 HW43_17845 HW43_RS18360 3716516 3717058 - formate hydrogenlyase complex iron-sulfur subunit electron transfer protein for hydrogenase-3%3B the formate hydrogenlyase complex comprises of a formate dehydrogenase%2C unidentified electron carriers and hydrogenase-3%3B in this non-energy conserving pathway%2C molecular hydrogen and carbodioxide are released from formate gene gene3669 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18360 HW43_RS18365 HW43_17850 hycE hycE 3717068 3718777 - formate hydrogenlyase subunit 5 formate hydrogenlyase subunit 5%3B HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide gene gene3670 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18365 HW43_RS18370 HW43_17855 hycD hycD 3718795 3719718 - hydrogenase 3 membrane subunit formate hydrogenlyase subunit 4%3B HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide gene gene3671 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18370 HW43_RS18375 HW43_17860 HW43_RS18375 3719721 3721547 - formate hydrogenlyase subunit 3 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen%3B formate hydrogenlyase comprises of a formate dehydrogenase%2C unidentified electron carriers and a hydrogenase (subunit 3) gene gene3672 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18375 HW43_RS18380 HW43_17865 HW43_RS18380 3721544 3722155 - formate hydrogenlyase subunit 2 gene gene3673 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18380 HW43_RS18385 HW43_25565 HW43_RS18385 3722056 3722364 + hypothetical protein gene gene3674 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18385 HW43_RS18390 HW43_17870 HW43_RS18390 3722280 3722741 - formate hydrogenlyase regulatory protein HycA regulates several genes involved in the formate hydrogenlyase system%3B seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon gene gene3675 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18390 HW43_RS18395 HW43_17880 hypA hypA 3722953 3723303 + protein HypA plays a role in hydrogenase nickel cofactor insertion gene gene3676 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18395 HW43_RS18400 HW43_17885 HW43_RS18400 3723307 3724179 + hydrogenase isoenzymes nickel incorporation protein HypB GTP hydrolase involved in nickel liganding into hydrogenases gene gene3677 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18400 HW43_RS18405 HW43_17890 HW43_RS18405 3724170 3724442 + hydrogenase assembly protein HypC HypC%3B accessory protein necessary for maturation of the hydrogenase isoforms 1%2C 2 and 3%3B forms a complex with HypD%2C HypE%2C and HypF proteins%2C which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase gene gene3678 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18405 HW43_RS18410 HW43_17895 HW43_RS18410 3724442 3725563 + hydrogenase formation protein HypD necessary for the synthesis of all three hydrogenase isoenzymes gene gene3679 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18410 HW43_RS18415 HW43_17900 HW43_RS18415 3725560 3726570 + carbamoyl dehydratase hydrogenase isoenzymes formation protein%3B involved in the formation of the cyanate group of the large subunit of the hydrogenase%3B catalyzes the formation of thiocyanate from thiocarbamate gene gene3680 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18415 HW43_RS18420 HW43_17905 HW43_RS18420 3726644 3728722 + transcriptional regulator regulates the expression of formate dehydrogenase H and hydrogenase-3 structural genes gene gene3681 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18420 HW43_RS18425 HW43_17910 HW43_RS18425 3728759 3729112 - hypothetical protein gene gene3682 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18425 HW43_RS18430 HW43_17915 HW43_RS18430 3729144 3729323 - hypothetical protein gene gene3683 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18430 HW43_RS18435 HW43_17920 HW43_RS18435 3729399 3731960 + DNA mismatch repair protein MutS This protein performs the mismatch recognition step during the DNA repair process gene gene3684 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18435 HW43_RS18440 HW43_17925 HW43_RS18440 3732066 3732722 + serine/threonine protein phosphatase gene gene3685 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18440 HW43_RS18445 HW43_17930 HW43_RS18445 3732773 3733540 - DeoR family transcriptional regulator gene gene3686 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18445 HW43_RS18450 HW43_17935 HW43_RS18450 3733736 3734644 + oxidoreductase gene gene3687 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18450 HW43_RS18455 HW43_17940 HW43_RS18455 3734641 3735903 + membrane protein gene gene3688 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18455 HW43_RS18460 HW43_17945 HW43_RS18460 3735900 3736538 + class II aldolase gene gene3689 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18460 HW43_RS18465 HW43_17950 HW43_RS18465 3736543 3737319 + hypothetical protein gene gene3690 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18465 HW43_RS18470 HW43_17955 HW43_RS18470 3737408 3738772 + transporter member of the Gnt family of gluconate transporters%3B not involved in gluconate transport%3B unknown function gene gene3691 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18470 HW43_RS18475 HW43_17960 HW43_RS18475 3738811 3739047 - 4-hydroxybenzoate decarboxylase gene gene3692 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18475 HW43_RS18480 HW43_17965 HW43_RS18480 3739058 3740485 - phenolic acid decarboxylase subunit C gene gene3693 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18480 HW43_RS18485 HW43_17970 HW43_RS18485 3740485 3741078 - aromatic acid decarboxylase gene gene3694 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18485 HW43_RS18490 HW43_17975 HW43_RS18490 3741225 3741632 + transcriptional regulator HosA gene gene3695 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18490 HW43_RS18495 HW43_17980 HW43_RS18495 3741753 3742745 - RNA polymerase sigma factor RpoS sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B this sigma factor controls a regulon of genes required for protection against external stresses gene gene3696 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18495 HW43_RS18500 HW43_17985 nlpD nlpD 3742808 3743947 - lipoprotein NlpD outer membrane lipoprotein involved in stationary-phase cell survival%3B similar to LppB virulence determinant from Haemophilus somnus gene gene3697 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18500 HW43_RS18505 HW43_17990 pcm pcm 3744087 3744713 - protein-L-isoaspartate O-methyltransferase catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins gene gene3698 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18505 HW43_RS18510 HW43_17995 surE surE 3744707 3745468 - 5'/3'-nucleotidase SurE broad specificity 5'(3')-nucleotidase and polyphosphatase gene gene3699 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18510 HW43_RS18515 HW43_18000 truD truD 3745449 3746498 - tRNA pseudouridine synthase D catalyzes the modification of U13 in tRNA(Glu) gene gene3700 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18515 HW43_RS18520 HW43_18005 ispF ispF 3746495 3746974 - 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate gene gene3701 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18520 HW43_RS18525 HW43_18010 HW43_RS18525 3746974 3747684 - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase gene gene3702 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18525 HW43_RS18530 HW43_18015 ftsB ftsB 3747703 3748014 - cell division protein FtsB forms a complex with FtsL and FtsQ%3B colocalizes to the septal region of the dividing cell%3B membrane protein gene gene3703 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18530 HW43_RS18535 HW43_18020 HW43_RS18535 3748208 3748531 - hypothetical protein gene gene3704 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18535 HW43_RS18540 HW43_18025 HW43_RS18540 3748581 3749186 - adenylyl-sulfate kinase converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate%3B in Escherichia coli this enzyme functions in cysteine biosynthesis gene gene3705 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18540 HW43_RS18545 HW43_18030 cysN cysN 3749186 3750613 - sulfate adenylyltransferase subunit 1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate%3B in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step%3B forms a heterodimer with CysD%3B part of the GTP-binding elongation factor family CysN/NodQ gene gene3706 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18545 HW43_RS18550 HW43_18035 HW43_RS18550 3750615 3751523 - sulfate adenylyltransferase subunit 2 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP gene gene3707 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18550 HW43_RS18555 HW43_18040 HW43_RS18555 3751775 3752812 + alkaline phosphatase isozyme conversion aminopeptidase catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3 gene gene3708 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18555 HW43_RS18560 HW43_18045 HW43_RS18560 3753629 3753922 - CRISPR-associated endonuclease Cas2 gene gene3709 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18560 HW43_RS18565 HW43_18050 HW43_RS18565 3753922 3754842 - subtype I-E CRISPR-associated endonuclease Cas1 gene gene3710 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18565 HW43_RS18570 HW43_18055 HW43_RS18570 3754839 3755489 - CRISPR-associated protein Cas6 gene gene3711 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18570 HW43_RS18575 HW43_18060 HW43_RS18575 3755471 3756217 - hypothetical protein gene gene3712 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18575 HW43_RS18580 HW43_18065 HW43_RS18580 3756228 3757283 - CRISPR-associated protein Cse4 gene gene3713 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18580 HW43_RS18585 HW43_18070 HW43_RS18585 3757295 3757834 - transposase gene gene3714 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18585 HW43_RS18590 HW43_18075 HW43_RS18590 3757831 3759393 - CRISPR-associated protein CasA gene gene3715 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18590 HW43_RS18595 HW43_18080 HW43_RS18595 3759491 3762190 - helicase gene gene3716 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18595 HW43_RS18600 HW43_18085 HW43_RS18600 3762384 3762536 - protein hokG gene gene3717 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18600 HW43_RS18605 HW43_18090 HW43_RS18605 3762801 3763535 - phosphoadenosine phosphosulfate reductase catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite gene gene3718 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18605 HW43_RS18610 HW43_18095 HW43_RS18610 3763609 3765321 - sulfite reductase subunit beta hemoprotein%3B NADPH dependent%3B with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide gene gene3719 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18610 HW43_RS18615 HW43_18100 cysJ cysJ 3765321 3767120 - sulfite reductase subunit alpha catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate%3B a flavoprotein with flavin reductase activity gene gene3720 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18615 HW43_RS18620 HW43_18105 HW43_RS18620 3767439 3767801 + 6-carboxy-5%2C6%2C7%2C8-tetrahydropterin synthase gene gene3721 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18620 HW43_RS18625 HW43_18110 HW43_RS18625 3767879 3769150 + FAD-dependent oxidoreductase gene gene3722 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18625 HW43_RS18630 HW43_18115 HW43_RS18630 3769141 3769401 + ferredoxin gene gene3723 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18630 HW43_RS18635 HW43_18120 HW43_RS18635 3769418 3769993 + hypothetical protein gene gene3724 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18635 HW43_RS18640 HW43_18125 HW43_RS18640 3770141 3771001 - flavoprotein gene gene3725 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18640 HW43_RS18645 HW43_18130 HW43_RS18645 3770998 3771777 - flavoprotein gene gene3726 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18645 HW43_RS18650 HW43_18135 HW43_RS18650 3771755 3773092 - metabolite transporter gene gene3727 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18650 HW43_RS18655 HW43_18140 HW43_RS18655 3773186 3774640 - FAD-linked oxidoreductase gene gene3728 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18655 HW43_RS18660 HW43_18145 HW43_RS18660 3774710 3775495 - oxidoreductase gene gene3729 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18660 HW43_RS18665 HW43_18150 HW43_RS18665 3775814 3777091 + membrane protein gene gene3730 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18665 HW43_RS18670 HW43_18155 HW43_RS18670 3777118 3778596 + sugar kinase gene gene3731 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18670 HW43_RS18675 HW43_18160 HW43_RS18675 3780457 3781128 - 7-carboxy-7-deazaguanine synthase gene gene3732 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18675 HW43_RS18680 HW43_25570 HW43_RS18680 3781267 3781407 + hypothetical protein gene gene3733 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18680 HW43_RS18685 HW43_18170 HW43_RS18685 3781421 3782293 + hypothetical protein gene gene3734 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18685 HW43_RS18690 HW43_18175 eno eno 3782353 3783651 - enolase catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis gene gene3735 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18690 HW43_RS18695 HW43_18180 pyrG pyrG 3783739 3785376 - CTP synthase CTP synthase%3B cytidine triphosphate synthetase%3B catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen%3B in Escherichia coli this enzyme forms a homotetramer gene gene3736 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18695 HW43_RS18700 HW43_18185 mazG mazG 3785604 3786395 - nucleoside triphosphate pyrophosphohydrolase functions in degradation of stringent response intracellular messenger ppGpp%3B in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF%3B activity of MazG is inhibited by MazEF in vitro%3B ppGpp inhibits mazEF expression%3B MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation%3B MazG also interacts with the GTPase protein Era gene gene3737 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18700 HW43_RS18705 HW43_18190 HW43_RS18705 3786466 3786801 - toxin ChpA%3B endoribonuclease%3B toxin of the MazF-MazE (ChpA-ChpR) toxin-antitoxin system gene gene3738 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18705 HW43_RS18710 HW43_18195 HW43_RS18710 3786801 3787049 - antitoxin MazE part of the MazF-MazE toxin-antitoxin system%3B conteracts MazF gene gene3739 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18710 HW43_RS18715 HW43_18200 relA relA 3787127 3789361 - GTP pyrophosphokinase (p)ppGpp synthetase%3B catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP gene gene3740 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18715 HW43_RS18720 HW43_18205 rumA rumA 3789409 3790710 - 23S rRNA methyltransferase in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA%3B binds an iron-sulfur cluster [4Fe-4S] gene gene3741 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18720 HW43_RS18725 HW43_18210 HW43_RS18725 3790767 3793523 + signal transduction histidine kinase part of the two-component regulatory system with UvrY%3B involved in the regulation of carbon metabolism via the csrA/csrB regulatory system gene gene3742 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18725 HW43_RS18730 HW43_18215 gudD gudD 3793755 3795095 - glucarate dehydratase catalyzes the formation of 5-keto-4-deoxy-D-glucarate from glucarate gene gene3743 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18730 HW43_RS18735 HW43_18220 HW43_RS18735 3795116 3796456 - glucarate dehydratase gene gene3744 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18735 HW43_RS18740 HW43_18225 HW43_RS18740 3796458 3797810 - glucarate transporter gene gene3745 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18740 HW43_RS18745 HW43_18230 HW43_RS18745 3798245 3798694 - flavodoxin An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group gene gene3746 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18745 HW43_RS18750 HW43_18235 HW43_RS18750 3798712 3799494 - tRNA pseudouridine synthase C catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp gene gene3747 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18750 HW43_RS18755 HW43_18240 HW43_RS18755 3799494 3799823 - DUF446 domain-containing protein gene gene3748 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18755 HW43_RS18760 HW43_25575 HW43_RS18760 3800070 3800195 - hypothetical protein gene gene3749 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18760 HW43_RS18765 HW43_18250 HW43_RS18765 3800445 3800990 - protein Syd SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function gene gene3750 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18765 HW43_RS18770 HW43_18255 queF queF 3801058 3801906 + NADPH-dependent 7-cyano-7-deazaguanine reductase catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis gene gene3751 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18770 HW43_RS18775 HW43_18260 HW43_RS18775 3802018 3803382 + LOG family protein YgdH gene gene3752 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18775 HW43_RS18780 HW43_18265 HW43_RS18780 3803939 3805228 + serine transporter gene gene3753 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18780 HW43_RS18785 HW43_18270 HW43_RS18785 3805286 3806653 + L-serine dehydratase catalyzes the formation of pyruvate from serine gene gene3754 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18785 HW43_RS18790 HW43_18275 HW43_RS18790 3806765 3807520 + flap endonuclease Xni similar to flap endonuclease%3B FEN family%3B protein from E. coli does not have exonuclease activity gene gene3755 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18790 HW43_RS18795 HW43_18280 HW43_RS18795 3807575 3808723 - lactaldehyde reductase gene gene3756 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18795 HW43_RS18800 HW43_18285 HW43_RS18800 3808751 3809398 - fuculose phosphate aldolase catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate gene gene3757 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18800 HW43_RS18805 HW43_18290 HW43_RS18805 3809945 3811261 + L-fucose-proton symporter gene gene3758 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18805 HW43_RS18810 HW43_18295 fucI fucI 3811294 3813069 + L-fucose isomerase catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose gene gene3759 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18810 HW43_RS18815 HW43_18300 HW43_RS18815 3813178 3814596 + L-fuculokinase gene gene3760 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18815 HW43_RS18820 HW43_18305 HW43_RS18820 3814598 3815020 + L-fucose mutarotase gene gene3761 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18820 HW43_RS18825 HW43_18310 HW43_RS18825 3815078 3815809 + l-fucose operon activator regulates expression of genes involved in L-fucose utilization gene gene3762 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18825 HW43_RS18830 HW43_18315 HW43_RS18830 3815853 3816953 - ribosomal RNA large subunit methyltransferase M gene gene3763 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18830 HW43_RS18835 HW43_18320 HW43_RS18835 3816946 3817341 - hypothetical protein gene gene3764 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18835 HW43_RS18840 HW43_18325 HW43_RS18840 3817360 3818277 - glycine cleavage system transcriptional activator Glycine cleavage system transcriptional activator%3B activates the gcvTHP operon in the presence of glycine and represses the operon in its absence gene gene3765 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18840 HW43_RS18845 HW43_18330 HW43_RS18845 3818628 3818855 - DUF903 domain-containing protein gene gene3766 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18845 HW43_RS18850 HW43_18335 HW43_RS18850 3819047 3820252 + cysteine sulfinate desulfinase gene gene3767 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18850 HW43_RS18855 HW43_18340 HW43_RS18855 3820252 3820695 + sulfur acceptor protein CsdE binds and activates CsdA%3B Fe-S protein gene gene3768 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18855 HW43_RS18860 HW43_18345 HW43_RS18860 3820746 3821552 - tRNA threonylcarbamoyladenosine dehydratase accepts sulfur from CsdA gene gene3769 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18860 HW43_RS18865 HW43_18350 mltA mltA 3821629 3822726 - murein transglycosylase membrane-bound%2C lytic%3B catalyzes the cleavage of the beta-1%2C4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues gene gene3770 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18865 HW43_RS18870 HW43_18355 HW43_RS18870 3822935 3823011 + tRNA-Met tRNA gene3771 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18870 HW43_RS18875 HW43_18360 HW43_RS18875 3823045 3823121 + tRNA-Met tRNA gene3772 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18875 HW43_RS18880 HW43_18365 HW43_RS18880 3823154 3823230 + tRNA-Met tRNA gene3773 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18880 HW43_RS18885 HW43_18370 HW43_RS18885 3823864 3824364 + hypothetical protein gene gene3774 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18885 HW43_RS18890 HW43_18375 HW43_RS18890 3824423 3825961 + hypothetical protein gene gene3775 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18890 HW43_RS18895 HW43_18380 HW43_RS18895 3825979 3827316 + hypothetical protein gene gene3776 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18895 HW43_RS18900 HW43_18385 HW43_RS18900 3827313 3827978 + type VI secretion protein ImpK gene gene3777 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18900 HW43_RS18905 HW43_18390 HW43_RS18905 3827991 3829643 + hypothetical protein gene gene3778 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18905 HW43_RS18910 HW43_18395 HW43_RS18910 3829701 3830192 + Hcp family type VI secretion system effector gene gene3779 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18910 HW43_RS18915 HW43_18400 HW43_RS18915 3830383 3833028 + protein disaggregation chaperone gene gene3780 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18915 HW43_RS18920 HW43_18405 HW43_RS18920 3833040 3834314 + hypothetical protein gene gene3781 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18920 HW43_RS18925 HW43_18410 HW43_RS18925 3834317 3835138 + hypothetical protein gene gene3782 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18925 HW43_RS18930 HW43_18415 HW43_RS18930 3835182 3835736 + hypothetical protein gene gene3783 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18930 HW43_RS18935 HW43_18420 HW43_RS18935 3835777 3837726 + hypothetical protein gene gene3784 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18935 HW43_RS18940 HW43_18425 HW43_RS18940 3837735 3838271 + hypothetical protein gene gene3785 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18940 HW43_RS18945 HW43_18430 HW43_RS18945 3838325 3840838 + hypothetical protein gene gene3786 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18945 HW43_RS18950 HW43_18435 HW43_RS18950 3840860 3841462 + hypothetical protein gene gene3787 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18950 HW43_RS18955 HW43_18440 HW43_RS18955 3841464 3842015 + hypothetical protein gene gene3788 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18955 HW43_RS18960 HW43_18445 HW43_RS18960 3842093 3843307 + hypothetical protein gene gene3789 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18960 HW43_RS18965 HW43_18450 HW43_RS18965 3843307 3844206 + hypothetical protein gene gene3790 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18965 HW43_RS18970 HW43_18455 HW43_RS18970 3844172 3845089 + hypothetical protein gene gene3791 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18970 HW43_RS18975 HW43_18460 HW43_RS18975 3845086 3845484 + hypothetical protein gene gene3792 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18975 HW43_RS18980 HW43_25580 HW43_RS18980 3845797 3846090 + hypothetical protein gene gene3793 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18980 HW43_RS18985 HW43_18470 HW43_RS18985 3846191 3847549 + hypothetical protein gene gene3794 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18985 HW43_RS18990 HW43_25585 HW43_RS18990 3847696 3848103 + type VI secretion system lysozyme-like protein gene gene3795 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18990 HW43_RS18995 HW43_18480 HW43_RS18995 3848103 3848585 + hypothetical protein gene gene3796 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS18995 HW43_RS19000 HW43_18485 HW43_RS19000 3848650 3849198 + transcriptional regulator gene gene3797 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19000 HW43_RS19005 HW43_18490 amiC amiC 3849539 3850792 - N-acetylmuramoyl-L-alanine amidase hydrolyzes the bond between N-acetylmuramic acid and amino acid residues in peptidoglycan gene gene3798 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19005 HW43_RS19010 HW43_18495 HW43_RS19010 3851024 3852355 + amino-acid acetyltransferase catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis gene gene3799 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19010 HW43_RS19015 HW43_18500 recD recD 3852417 3854243 - RecBCD enzyme subunit RecD helicase/nuclease%3B with RecBC catalyzes the exonucleolytic cleavage of DNA%3B RecD has 5' to 3' helicase activity gene gene3800 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19015 HW43_RS19020 HW43_18505 recB recB 3854243 3857785 - exonuclease V subunit beta helicase/nuclease%3B with RecCD catalyzes the exonucleolytic cleavage of DNA%3B RecD has 5' to 3' helicase activity gene gene3801 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19020 HW43_RS19025 HW43_18510 HW43_RS19025 3857778 3860666 - protease 3 degrades small peptides gene gene3802 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19025 HW43_RS19030 HW43_18515 recC recC 3860841 3864209 - exonuclease V subunit gamma catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides%3B component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination gene gene3803 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19030 HW43_RS19035 HW43_18520 HW43_RS19035 3864222 3864545 - hypothetical protein gene gene3804 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19035 HW43_RS19040 HW43_18525 HW43_RS19040 3864530 3864937 - hypothetical protein gene gene3805 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19040 HW43_RS19045 HW43_18530 HW43_RS19045 3864934 3865497 - hypothetical protein gene gene3806 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19045 HW43_RS19050 HW43_18535 HW43_RS19050 3865488 3865958 - prepilin peptidase-dependent protein A gene gene3807 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19050 HW43_RS19055 HW43_18540 HW43_RS19055 3866143 3866937 - thymidylate synthase gene gene3808 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19055 HW43_RS19060 HW43_18545 HW43_RS19060 3866944 3867819 - prolipoprotein diacylglyceryl transferase gene gene3809 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19060 HW43_RS19065 HW43_18550 HW43_RS19065 3867970 3870216 - phosphoenolpyruvate-protein phosphotransferase member of a second PTS chain involved in nitrogen metabolism%3B PtsP phosphorylates NPr gene gene3810 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19065 HW43_RS19070 HW43_18555 HW43_RS19070 3870229 3870759 - RNA pyrophosphohydrolase hydrolyzes diadenosine polyphosphate gene gene3811 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19070 HW43_RS19075 HW43_25590 HW43_RS19075 3871071 3871265 + hypothetical protein gene gene3812 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19075 HW43_RS19080 HW43_25595 HW43_RS19080 3871204 3871365 + hypothetical protein gene gene3813 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19080 HW43_RS19085 HW43_18560 HW43_RS19085 3871444 3872133 + DNA mismatch repair protein MutH MutH%3B Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair gene gene3814 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19085 HW43_RS19090 HW43_18565 HW43_RS19090 3872202 3872915 + membrane protein gene gene3815 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19090 HW43_RS19095 HW43_18570 HW43_RS19095 3873053 3873271 + hypothetical protein gene gene3816 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19095 HW43_RS19100 HW43_18575 tas tas 3873379 3874419 + protein tas complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain%3B member of the aldo/keto reductase 2 family%3B crystal structure of purified Escherichia coli protein shows bound NADPH gene gene3817 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19100 HW43_RS19105 HW43_18580 HW43_RS19105 3874451 3875644 - lysophospholipid transporter LplT gene gene3818 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19105 HW43_RS19110 HW43_18585 HW43_RS19110 3875637 3877796 - bifunctional protein Aas Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 gene gene3819 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19110 HW43_RS19115 HW43_18590 HW43_RS19115 3878382 3879413 + transcriptional regulator controls transcription of galETKM gene gene3820 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19115 HW43_RS19120 HW43_18595 HW43_RS19120 3879420 3880682 - diaminopimelate decarboxylase catalyzes the decarboxylation of diaminopimelate into lysine%3B pyridoxal phosphate(PLP)-binding gene gene3821 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19120 HW43_RS19125 HW43_18600 HW43_RS19125 3880804 3881739 + LysR family transcriptional regulator activates the transcription of the lysA gene encoding diaminopimelate decarboxylase gene gene3822 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19125 HW43_RS19130 HW43_18605 HW43_RS19130 3881726 3882418 - racemase gene gene3823 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19130 HW43_RS19135 HW43_18610 HW43_RS19135 3882547 3883965 - arabinose-proton symporter gene gene3824 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19135 HW43_RS19140 HW43_18615 HW43_RS19140 3884273 3885034 - 2-deoxy-D-gluconate 3-dehydrogenase catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate gene gene3825 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19140 HW43_RS19145 HW43_18620 HW43_RS19145 3885064 3885900 - 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase%3B catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2%2C5-hexodiulosonate gene gene3826 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19145 HW43_RS19150 HW43_18625 HW43_RS19150 3886187 3887368 - acetyl-CoA acetyltransferase gene gene3827 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19150 HW43_RS19155 HW43_18630 HW43_RS19155 3887623 3888852 + transporter gene gene3828 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19155 HW43_RS19160 HW43_18635 HW43_RS19160 3889426 3889944 + LuxR family transcriptional regulator gene gene3829 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19160 HW43_RS19165 HW43_18640 HW43_RS19165 3890277 3891086 + hypothetical protein gene gene3830 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19165 HW43_RS19170 HW43_18645 HW43_RS19170 3891079 3891561 + hypothetical protein gene gene3831 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19170 HW43_RS19175 HW43_18655 HW43_RS19175 3892328 3892817 + hypothetical protein gene gene3832 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19175 HW43_RS19180 HW43_18660 HW43_RS19180 3893042 3893533 + hypothetical protein gene gene3833 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19180 HW43_RS19185 HW43_18665 HW43_RS19185 3893867 3895243 + transcriptional regulator gene gene3834 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19185 HW43_RS19190 HW43_18670 HW43_RS19190 3895411 3895629 + hypothetical protein gene gene3835 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19190 HW43_RS19195 HW43_18675 HW43_RS19195 3895814 3896188 + lytic transglycosylase gene gene3836 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19195 HW43_RS19200 HW43_18680 HW43_RS19200 3896233 3896679 - LuxR family transcriptional regulator gene gene3837 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19200 HW43_RS19205 HW43_18685 HW43_RS19205 3896710 3896865 - transcriptional regulator gene gene3838 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19205 HW43_RS19210 HW43_18690 HW43_RS19210 3897086 3897517 - hypothetical protein gene gene3839 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19210 HW43_RS19215 HW43_25600 HW43_RS19215 3897520 3897792 - hypothetical protein gene gene3840 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19215 HW43_RS19220 HW43_25605 HW43_RS19220 3897734 3897889 - secretion protein gene gene3841 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19220 HW43_RS19225 HW43_25610 HW43_RS19225 3898331 3898867 - type III secretion system lipoprotein PrgK required for invasion of epithelial cells gene gene3842 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19225 HW43_RS19230 HW43_18700 HW43_RS19230 3899106 3899393 - type III secretion system protein EprJ gene gene3843 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19230 HW43_RS19235 HW43_18705 HW43_RS19235 3899498 3899653 - type III secretion protein gene gene3844 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19235 HW43_RS19240 HW43_25615 HW43_RS19240 3899667 3900849 - type III secretion protein gene gene3845 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19240 HW43_RS19245 HW43_18720 HW43_RS19245 3901107 3901538 + LuxR family transcriptional regulator gene gene3846 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19245 HW43_RS19250 HW43_18725 HW43_RS19250 3901609 3901902 + invasion protein gene gene3847 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19250 HW43_RS19255 HW43_18730 HW43_RS19255 3901963 3902325 - hypothetical protein gene gene3848 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19255 HW43_RS19260 HW43_18735 HW43_RS19260 3902352 3903083 - hypothetical protein gene gene3849 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19260 HW43_RS19265 HW43_18740 HW43_RS19265 3903092 3903859 - type III secretion protein gene gene3850 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19265 HW43_RS19270 HW43_18745 HW43_RS19270 3903861 3904121 - type III secretion system protein SpaQ involved in the surface presentation of antigens needed for the invasion of Salmonella into host cells gene gene3851 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19270 HW43_RS19275 HW43_25620 HW43_RS19275 3904131 3904796 - type III secretion system protein gene gene3852 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19275 HW43_RS19280 HW43_18755 HW43_RS19280 3904786 3905307 - type III secretion protein gene gene3853 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19280 HW43_RS19285 HW43_18760 HW43_RS19285 3905368 3905733 - hypothetical protein gene gene3854 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19285 HW43_RS19290 HW43_18765 HW43_RS19290 3905865 3907475 - hypothetical protein gene gene3855 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19290 HW43_RS19295 HW43_18770 HW43_RS19295 3907709 3907782 - tRNA-Gly tRNA gene3856 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19295 HW43_RS19300 HW43_18775 HW43_RS19300 3907861 3908616 - lipoprotein gene gene3857 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19300 HW43_RS19305 HW43_18780 HW43_RS19305 3909031 3911328 + xanthine dehydrogenase subunit A molybdenum cofactor-binding protein%3B participates in purine salvage gene gene3858 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19305 HW43_RS19310 HW43_18785 HW43_RS19310 3911339 3912217 + xanthine dehydrogenase FAD-binding subunit FAD-binding subunit%3B with XdhA and XdhC participates in purine salvage gene gene3859 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19310 HW43_RS19315 HW43_18790 HW43_RS19315 3912214 3912693 + xanthine dehydrogenase subunit C iron-sulfur-binding subunit%3B with XdhA and XdhB participates in purine salvage gene gene3860 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19315 HW43_RS19320 HW43_18795 HW43_RS19320 3912733 3914511 - Fis family transcriptional regulator gene gene3861 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19320 HW43_RS19325 HW43_18800 HW43_RS19325 3914990 3916177 + ornithine carbamoyltransferase gene gene3862 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19325 HW43_RS19330 HW43_18805 HW43_RS19330 3916235 3917431 + diaminopropionate ammonia-lyase catalyzes the formation of pyruvate from 2%2C3-diaminopropionate gene gene3863 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19330 HW43_RS19335 HW43_18810 HW43_RS19335 3917489 3918700 + peptidase Zn-dependent extracellular dipeptidase%3B similar to succinyl-diaminopimelate desuccinylases gene gene3864 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19335 HW43_RS19340 HW43_18815 HW43_RS19340 3918753 3920138 + D-phenylhydantoinase catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position gene gene3865 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19340 HW43_RS19345 HW43_18820 HW43_RS19345 3920186 3921118 + carbamate kinase-like protein YqeA gene gene3866 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19345 HW43_RS19350 HW43_18825 HW43_RS19350 3921159 3922784 - XdhC-CoxI family protein with NAD(P)-binding Rossman fold gene gene3867 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19350 HW43_RS19355 HW43_18830 HW43_RS19355 3922832 3923602 - selenium-dependent hydroxylase accessory protein gene gene3868 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19355 HW43_RS19360 HW43_18835 HW43_RS19360 3923705 3924283 + hypothetical protein gene gene3869 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19360 HW43_RS19365 HW43_18840 HW43_RS19365 3924605 3927703 + selenate reductase with YgfM and YgfN forms a selenate reductase%2C which seems to catalyze the reduction of selenate to selenite%3B YgfK mutants are unable to reduce selenate%3B involved in purine salvage process%3B seems to act as an oxidoreductase%2C but sequence similarity suggests it is a dihydrothymine dehydrogenase gene gene3870 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19365 HW43_RS19370 HW43_18845 HW43_RS19370 3927706 3929034 + chlorohydrolase/aminohydrolase in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS gene gene3871 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19370 HW43_RS19375 HW43_18850 HW43_RS19375 3929085 3929864 + oxidoreductase gene gene3872 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19375 HW43_RS19380 HW43_18855 HW43_RS19380 3929861 3932731 + hypoxanthine oxidase XdhD gene gene3873 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19380 HW43_RS19385 HW43_18860 HW43_RS19385 3932896 3934296 + xanthine permease XanQ high-affinity transporter for xanthine gene gene3874 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19385 HW43_RS19390 HW43_18865 HW43_RS19390 3934314 3935630 + guanine deaminase Catalyzes the deamination of guanine gene gene3875 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19390 HW43_RS19395 HW43_18870 HW43_RS19395 3935666 3937033 + guanine/hypoxanthine permease GhxQ gene gene3876 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19395 HW43_RS19400 HW43_18875 HW43_RS19400 3937069 3937557 - oxidoreductase gene gene3877 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19400 HW43_RS19405 HW43_18880 HW43_RS19405 3937557 3939476 - oxidoreductase Fe-S-binding subunit unknown function%3B in E. coli the aegA gene is regulated by Fnr%2C NarXL%2C and NarQ (but not ArcA)%2C induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) gene gene3878 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19405 HW43_RS19410 HW43_25625 HW43_RS19410 3939779 3939967 + hypothetical protein gene gene3879 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19410 HW43_RS19415 HW43_18885 HW43_RS19415 3939912 3941360 + uric acid transporter UacT gene gene3880 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19415 HW43_RS19420 HW43_25630 HW43_RS19420 3941362 3941487 + hypothetical protein gene gene3881 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19420 HW43_RS19425 HW43_18895 HW43_RS19425 3941610 3942158 + isopentenyl-diphosphate delta isomerase catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate gene gene3882 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19425 HW43_RS19430 HW43_18900 lysS lysS 3942201 3943718 - lysine--tRNA ligase class II%3B LysRS2%3B catalyzes a two-step reaction%2C first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B in Methanosarcina barkeri%2C LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 gene gene3883 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19430 HW43_RS19435 HW43_18905 HW43_RS19435 3943728 3944609 - peptide chain release factor 2 catalyzes the release of newly synthesized polypeptide chains at the stop codons UAA and UGA gene gene3884 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19435 HW43_RS19440 HW43_18915 HW43_RS19440 3944917 3946650 - ssDNA exonuclease RecJ 5'-3' single-stranded-DNA-specific exonuclease gene gene3885 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19440 HW43_RS19445 HW43_18920 HW43_RS19445 3946656 3947366 - thiol:disulfide interchange protein DsbC DsbC%3B periplasmic protein with protein disulfide isomerase activity%3B this protein also shows disulfide oxidoreductase activity gene gene3886 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19445 HW43_RS19450 HW43_18925 xerD xerD 3947391 3948287 - tyrosine recombinase XerD site-specific tyrosine recombinase which cuts and rejoins DNA molecules%3B binds cooperatively to specific DNA consensus sites%3B forms a heterotetrameric complex with XerC%3B XerCD exhibit similar sequences%3B essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation%3B XerD specifically exchanges the bottom strands%3B cell division protein FtsK may regulate the XerCD complex%3B enzyme from Streptococcus group has unusual active site motifs gene gene3887 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19450 HW43_RS19455 HW43_18930 HW43_RS19455 3948399 3948920 + flavodoxin-2 An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic gene gene3888 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19455 HW43_RS19460 HW43_18935 HW43_RS19460 3948960 3949367 - toxin CptA gene gene3889 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19460 HW43_RS19465 HW43_18940 HW43_RS19465 3949348 3949614 - antitoxin CptB gene gene3890 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19465 HW43_RS19470 HW43_18950 ygfZ ygfZ 3949857 3950837 + tRNA-modifying protein YgfZ physiological role is not clear%3B not essential for growth but mutants grow poorly%3B mutations suppress hda null mutations%3B may be involved in regulation of ATP-DnaA levels%3B may also be involved in regulation of tRNA modifications%3B can bind folic acid and tetrahydrofolate%3B forms a three domain ring-like structure with a central channel%3B structurally similar to DMGO protein from A. globiformis%3B shows sequence similarity to yeast CAF17 transcriptional regulato%3B Hda supressor gene gene3891 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19470 HW43_RS19475 HW43_18955 HW43_RS19475 3950914 3951573 - hemolysin gene gene3892 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19475 HW43_RS19480 HW43_18960 HW43_RS19480 3951737 3952048 - hypothetical protein gene gene3893 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19480 HW43_RS19485 HW43_18965 HW43_RS19485 3952093 3953526 + 6-phospho-beta-glucosidase gene gene3894 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19485 HW43_RS19490 HW43_18970 HW43_RS19490 3953583 3954326 - NAD(P)-binding oxidoreductase gene gene3895 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19490 HW43_RS19495 HW43_18975 HW43_RS19495 3954593 3957466 - glycine dehydrogenase acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine gene gene3896 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19495 HW43_RS19500 HW43_18980 HW43_RS19500 3957585 3957974 - glycine cleavage system protein H part of multienzyme complex composed of H%2C L%2C P%2C and T proteins which catalyzes oxidation of glycine to yield carbon dioxide%2C ammonia%2C 5%2C10-CH2-H4folate and a reduced pyridine nucleotide%3B protein H is involved in transfer of methylamine group from the P to T protein%3B covalently bound to a lipoyl cofactor gene gene3897 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19500 HW43_RS19505 HW43_18985 gcvT gcvT 3957998 3959092 - aminomethyltransferase catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate%2C causing the release of ammonia and the generation of reduced GcvH protein gene gene3898 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19505 HW43_RS19510 HW43_18990 HW43_RS19510 3959539 3960741 - oxidoreductase gene gene3899 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19510 HW43_RS19515 HW43_18995 HW43_RS19515 3960764 3961942 - 2-octaprenyl-6-methoxyphenyl hydroxylase Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1%2C4-benzoquinone gene gene3900 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19515 HW43_RS19520 HW43_19000 HW43_RS19520 3961939 3963264 - proline aminopeptidase P II exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue%3B substrate can be as short as a dipeptide gene gene3901 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19520 HW43_RS19525 HW43_19005 HW43_RS19525 3963290 3963874 - hypothetical protein the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers%3B function unknown gene gene3902 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19525 HW43_RS19530 HW43_19010 HW43_RS19530 3964036 3964365 + cell division protein ZapA gene gene3903 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19530 HW43_RS19535 HW43_19015 HW43_RS19535 3964611 3965213 + 5-formyltetrahydrofolate cyclo-ligase ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms%3B unknown function gene gene3904 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19535 HW43_RS19540 HW43_25635 HW43_RS19540 3965386 3965615 - hypothetical protein gene gene3905 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19540 HW43_RS19545 HW43_19020 HW43_RS19545 3965994 3967226 - D-3-phosphoglycerate dehydrogenase catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis%3B can also reduce alpha ketoglutarate to form 2-hydroxyglutarate gene gene3906 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19545 HW43_RS19550 HW43_19025 HW43_RS19550 3967482 3968141 - ribose-5-phosphate isomerase A catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway gene gene3907 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19550 HW43_RS19555 HW43_19030 HW43_RS19555 3968197 3968427 - hypothetical protein gene gene3908 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19555 HW43_RS19560 HW43_19035 HW43_RS19560 3968569 3969462 + chromosome initiation inhibitor specific inhibitor of chromosomal initiation of replication in vitro%3B binds the three 13-mers in the origin (oriC) to block initiation of replication%3B also controls genes involved in arginine transport gene gene3909 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19560 HW43_RS19565 HW43_19040 HW43_RS19565 3969666 3971810 + methylmalonyl-CoA mutase gene gene3910 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19565 HW43_RS19570 HW43_19045 HW43_RS19570 3971803 3972798 + protein kinase gene gene3911 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19570 HW43_RS19575 HW43_19050 HW43_RS19575 3972809 3973594 + methylmalonyl-CoA decarboxylase catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA gene gene3912 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19575 HW43_RS19580 HW43_19055 HW43_RS19580 3973618 3975096 + acetyl-CoA hydrolase gene gene3913 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19580 HW43_RS19585 HW43_19060 HW43_RS19585 3975093 3975989 - transcriptional regulator gene gene3914 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19585 HW43_RS19590 HW43_19065 HW43_RS19590 3976156 3976896 - oxidative stress defense protein gene gene3915 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19590 HW43_RS19595 HW43_19070 HW43_RS19595 3976989 3977582 - arginine exporter protein Involved in the export of arginine gene gene3916 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19595 HW43_RS19600 HW43_19075 HW43_RS19600 3977763 3978623 - mechanosensitive ion channel protein MscS participates in the regulation of osmotic pressure changes within the cel gene gene3917 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19600 HW43_RS19605 HW43_25640 HW43_RS19605 3978646 3978918 - hypothetical protein gene gene3918 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19605 HW43_RS19610 HW43_19080 HW43_RS19610 3978981 3980060 - fructose-bisphosphate aldolase catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1%2C6%2C bisphosphate gene gene3919 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19610 HW43_RS19615 HW43_19085 HW43_RS19615 3980275 3981438 - phosphoglycerate kinase gene gene3920 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19615 HW43_RS19620 HW43_19090 gapA gapA 3981488 3982507 - D-erythrose-4-phosphate dehydrogenase required for glycolysis%3B catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate gene gene3921 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19620 HW43_RS19625 HW43_19095 HW43_RS19625 3982879 3983310 + DNA-binding protein gene gene3922 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19625 HW43_RS19630 HW43_19100 HW43_RS19630 3983333 3983911 + membrane protein gene gene3923 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19630 HW43_RS19635 HW43_19105 HW43_RS19635 3983912 3984619 + cobalt ABC transporter permease gene gene3924 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19635 HW43_RS19640 HW43_19110 HW43_RS19640 3984607 3985284 + ABC transporter ATP-binding protein gene gene3925 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19640 HW43_RS19645 HW43_19115 HW43_RS19645 3985278 3985955 + ABC transporter ATP-binding protein gene gene3926 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19645 HW43_RS19650 HW43_19120 HW43_RS19650 3985927 3986640 - nucleoside triphosphate hydrolase gene gene3927 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19650 HW43_RS19655 HW43_19125 HW43_RS19655 3986637 3987146 - mannitol repressor gene gene3928 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19655 HW43_RS19660 HW43_19130 HW43_RS19660 3987168 3988133 - fructose 1%2C6-bisphosphatase gene gene3929 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19660 HW43_RS19665 HW43_19135 HW43_RS19665 3988130 3989407 - L-sorbose 1-phosphate reductase gene gene3930 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19665 HW43_RS19670 HW43_19140 HW43_RS19670 3989422 3990810 - PTS mannitol cryptic EIICB component CmtA with CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system%2C which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli%3B cytoplasmic protein gene gene3931 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19670 HW43_RS19675 HW43_19145 cmtB cmtB 3990838 3991281 - mannitol-specific cryptic phosphotransferase enzyme IIA component TolM%3B with CmtA (IIBC)%2C CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system%2C which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli%3B cytoplasmic protein gene gene3932 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19675 HW43_RS19680 HW43_19150 HW43_RS19680 3991595 3993586 - transketolase catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate%3B can transfer ketol groups between several groups%3B in Escherichia coli there are two tkt genes%2C tktA expressed during exponential growth and the tktB during stationary phase gene gene3933 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19680 HW43_RS19685 HW43_19155 HW43_RS19685 3993864 3994622 + metalloprotease gene gene3934 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19685 HW43_RS19690 HW43_19160 HW43_RS19690 3994678 3995421 - 4-hydroxy-2-ketovalerate aldolase gene gene3935 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19690 HW43_RS19695 HW43_19165 HW43_RS19695 3995408 3996517 - selenocysteine synthase gene gene3936 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19695 HW43_RS19700 HW43_19170 HW43_RS19700 3996521 3997378 - PTS fructose transporter subunit IID gene gene3937 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19700 HW43_RS19705 HW43_19175 HW43_RS19705 3997378 3998127 - PTS sorbose transporter subunit IIC gene gene3938 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19705 HW43_RS19710 HW43_19180 HW43_RS19710 3998153 3998638 - PTS sugar transporter gene gene3939 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19710 HW43_RS19715 HW43_19185 HW43_RS19715 3998649 3999077 - PTS fructose transporter subunit IIA gene gene3940 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19715 HW43_RS19720 HW43_19190 HW43_RS19720 3999196 4001994 - transcriptional regulator gene gene3941 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19720 HW43_RS19725 HW43_19195 HW43_RS19725 4002253 4003173 - agmatinase catalyzes the formation of putrescine from agmatine gene gene3942 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19725 HW43_RS19730 HW43_19200 HW43_RS19730 4003309 4004040 - membrane protein gene gene3943 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19730 HW43_RS19735 HW43_19205 HW43_RS19735 4004186 4006162 - biosynthetic arginine decarboxylase catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis gene gene3944 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19735 HW43_RS19740 HW43_25645 HW43_RS19740 4006171 4006302 - hypothetical protein gene gene3945 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19740 HW43_RS19745 HW43_25650 HW43_RS19745 4006438 4006653 + hypothetical protein gene gene3946 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19745 HW43_RS19750 HW43_19210 HW43_RS19750 4006650 4006901 - membrane protein gene gene3947 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19750 HW43_RS19755 HW43_19215 HW43_RS19755 4006957 4008111 + S-adenosylmethionine synthase catalyzes the formation of S-adenosylmethionine from methionine and ATP%3B methionine adenosyltransferase gene gene3948 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19755 HW43_RS19760 HW43_19220 HW43_RS19760 4008547 4009941 + galactose-proton symporter gene gene3949 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19760 HW43_RS19765 HW43_19225 HW43_RS19765 4010018 4010515 + protein SprT gene gene3950 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19765 HW43_RS19770 HW43_19230 HW43_RS19770 4010610 4011317 + endonuclease gene gene3951 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19770 HW43_RS19775 HW43_19235 HW43_RS19775 4011397 4012128 + 16S rRNA methyltransferase in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA%3B cells lacking this function can grow%2C but are outcompeted by wild-type%3B SAM-dependent m(3)U1498 methyltransferase gene gene3952 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19775 HW43_RS19780 HW43_19240 HW43_RS19780 4012141 4013091 + glutathione synthetase catalyzes the second step in the glutathione biosynthesis pathway%2C where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine %3D ADP + phosphate + glutathione gene gene3953 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19780 HW43_RS19785 HW43_19245 HW43_RS19785 4013200 4013763 + hypothetical protein gene gene3954 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19785 HW43_RS19790 HW43_19250 HW43_RS19790 4013763 4014179 + Holliday junction DNA helicase similar to RuvC resolvase with substantial differences%3B NMR structural information suggests this protein is monomeric%3B unknown cellular function gene gene3955 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19790 HW43_RS19795 HW43_19255 HW43_RS19795 4014363 4015244 - hypothetical protein gene gene3956 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19795 HW43_RS19800 HW43_19260 HW43_RS19800 4015361 4016065 + YggS family pyridoxal phosphate enzyme gene gene3957 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19800 HW43_RS19805 HW43_19265 HW43_RS19805 4016083 4016649 + hypothetical protein gene gene3958 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19805 HW43_RS19810 HW43_19270 HW43_RS19810 4016646 4016936 + hypothetical protein gene gene3959 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19810 HW43_RS19815 HW43_19275 HW43_RS19815 4016944 4017537 + non-canonical purine NTP pyrophosphatase HAM1-like protein%3B Rec-dependent growth%3B RgdB%3B yggV%3B it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine gene gene3960 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19815 HW43_RS19820 HW43_19280 HW43_RS19820 4017530 4018666 + radical SAM superfamily protein gene gene3961 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19820 HW43_RS19825 HW43_19285 HW43_RS19825 4018821 4019828 - hypothetical protein gene gene3962 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19825 HW43_RS19830 HW43_19290 ansB ansB 4019945 4020991 - L-asparaginase catalyzes the formation of aspartate from asparagine%2C periplasmic%3B regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis gene gene3963 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19830 HW43_RS19835 HW43_19295 HW43_RS19835 4021167 4021886 - hypothetical protein gene gene3964 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19835 HW43_RS19840 HW43_25655 HW43_RS19840 4021907 4022047 - hypothetical protein gene gene3965 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19840 HW43_RS19845 HW43_19300 HW43_RS19845 4022070 4022396 - hypothetical protein gene gene3966 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19845 HW43_RS19850 HW43_19305 trmB trmB 4022396 4023115 - tRNA (guanine-N(7)-)-methyltransferase tRNA (guanine-N(7)-)-methyltransferase%3B catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine gene gene3967 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19850 HW43_RS19855 HW43_19310 HW43_RS19855 4023276 4024328 + A/G-specific adenine glycosylase gene gene3968 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19855 HW43_RS19860 HW43_19315 HW43_RS19860 4024356 4024631 + Fe(2+)-trafficking protein protects iron-sulfur proteins against oxidative damage gene gene3969 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19860 HW43_RS19865 HW43_19320 mltC mltC 4024696 4025775 + murein transglycosylase Murein hydrolase C%3B membrane-bound%3B lytic%3B catalyzes the cleavage of the beta-1%2C4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues gene gene3970 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19865 HW43_RS19870 HW43_19325 HW43_RS19870 4025977 4027233 + nucleoside permease NupG gene gene3971 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19870 HW43_RS19875 HW43_19330 HW43_RS19875 4027283 4029418 - ornithine decarboxylase gene gene3972 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19875 HW43_RS19880 HW43_19335 HW43_RS19880 4029816 4030523 + DUF554 domain-containing protein gene gene3973 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19880 HW43_RS19885 HW43_19340 HW43_RS19885 4030629 4030704 + tRNA-Phe tRNA gene3974 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19885 HW43_RS19890 HW43_19345 HW43_RS19890 4030902 4032167 + integrase gene gene3975 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19890 HW43_RS19895 HW43_19350 HW43_RS19895 4032423 4033373 + hypothetical protein gene gene3976 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19895 HW43_RS19905 HW43_19360 HW43_RS19905 4033825 4035327 - sulfatase gene gene3977 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19905 HW43_RS19910 HW43_19365 HW43_RS19910 4035509 4036249 - adhesin gene gene3978 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19910 HW43_RS19915 HW43_19370 HW43_RS19915 4036637 4038463 + PAS domain-containing two-component system sensor histidine kinase with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism gene gene3979 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19915 HW43_RS19920 HW43_19375 HW43_RS19920 4038460 4039845 + acetoacetate metabolism regulatory protein AtoC DNA-binding response regulator in two-component regulatory system with ZraS%3B response regulator/sigma54 interaction protein gene gene3980 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19920 HW43_RS19925 HW43_19380 HW43_RS19925 4040041 4040703 + acetate CoA-transferase subunit alpha gene gene3981 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19925 HW43_RS19930 HW43_19385 HW43_RS19930 4040703 4041353 + acetate CoA-transferase subunit beta gene gene3982 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19930 HW43_RS19935 HW43_19390 HW43_RS19935 4041350 4042672 + short-chain fatty acids transporter gene gene3983 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19935 HW43_RS19940 HW43_19395 HW43_RS19940 4042703 4043887 + acetyl-CoA acetyltransferase Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase%2C catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation gene gene3984 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19940 HW43_RS19945 HW43_25665 HW43_RS19945 4044297 4044821 - hypothetical protein gene gene3985 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19945 HW43_RS19950 HW43_25670 HW43_RS19950 4045221 4045462 + transposase gene gene3986 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19950 HW43_RS19955 HW43_25675 HW43_RS19955 4045562 4045675 + hypothetical protein gene gene3987 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19955 HW43_RS19960 HW43_25680 HW43_RS19960 4045969 4046193 - hypothetical protein gene gene3988 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19960 HW43_RS19965 HW43_25685 HW43_RS19965 4046273 4046446 + hypothetical protein gene gene3989 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19965 HW43_RS19970 HW43_25690 HW43_RS19970 4046827 4046954 + transposase gene gene3990 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19970 HW43_RS19975 HW43_25695 HW43_RS19975 4047479 4047643 - hypothetical protein gene gene3991 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19975 HW43_RS19980 HW43_25700 HW43_RS19980 4048327 4048542 - hypothetical protein gene gene3992 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19980 HW43_RS19985 HW43_34160 HW43_RS19985 4049875 4050057 - hypothetical protein gene gene3993 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19985 HW43_RS19990 HW43_34165 HW43_RS19990 4049996 4052083 + ligand-gated channel IrgA-homologue adhesin (Iha)%3B TonB-dependent%3B acts as a specific receptor of enterobactin%3B fur-regulated%3B urovirulence factor gene gene3994 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19990 HW43_RS19995 HW43_25705 HW43_RS19995 4052074 4052400 - transposase gene gene3995 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS19995 HW43_RS20000 HW43_19440 btuB btuB 4052429 4054273 - vitamin B12/cobalamin outer membrane transporter involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space gene gene3996 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20000 HW43_RS20010 HW43_19445 HW43_RS20010 4055174 4055431 - hypothetical protein gene gene3999 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20010 HW43_RS20015 HW43_19450 HW43_RS20015 4055875 4056894 - transposase gene gene4000 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20015 HW43_RS20020 HW43_25715 HW43_RS20020 4056999 4058639 - sulfatase gene gene4001 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20020 HW43_RS20025 HW43_19460 HW43_RS20025 4058734 4059870 - porin gene gene4002 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20025 HW43_RS20030 HW43_25720 HW43_RS20030 4060546 4060754 + hypothetical protein gene gene4003 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20030 HW43_RS20035 HW43_25725 HW43_RS20035 4060741 4060930 + hypothetical protein gene gene4004 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20035 HW43_RS20040 HW43_19465 HW43_RS20040 4060933 4061121 - hypothetical protein gene gene4005 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20040 HW43_RS20045 HW43_19470 HW43_RS20045 4062007 4062744 + AraC family transcriptional regulator gene gene4006 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20045 HW43_RS20050 HW43_19475 HW43_RS20050 4063745 4067737 + autotransporter gene gene4007 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20050 HW43_RS20055 HW43_33715 HW43_RS20055 4068243 4068608 + hypothetical protein gene gene4008 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20055 HW43_RS20060 HW43_33720 HW43_RS20060 4068618 4068809 + hypothetical protein gene gene4009 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20060 HW43_RS20065 HW43_25730 HW43_RS20065 4068843 4069046 + flagellar biosynthesis protein FlgM gene gene4010 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20065 HW43_RS20070 HW43_19495 HW43_RS20070 4069079 4069426 - transposase gene gene4011 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20070 HW43_RS20075 HW43_19500 HW43_RS20075 4069550 4070194 - hypothetical protein gene gene4012 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20075 HW43_RS20080 HW43_19505 HW43_RS20080 4070215 4070484 - transcriptional regulator gene gene4013 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20080 HW43_RS20085 HW43_19510 HW43_RS20085 4070563 4071201 - transcriptional regulator gene gene4014 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20085 HW43_RS20090 HW43_19515 HW43_RS20090 4071186 4072418 - hypothetical protein gene gene4015 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20090 HW43_RS20095 HW43_19525 HW43_RS20095 4072918 4075086 - helicase gene gene4016 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20095 HW43_RS20100 HW43_25735 HW43_RS20100 4075083 4075599 - hypothetical protein gene gene4017 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20100 HW43_RS20105 HW43_25740 HW43_RS20105 4075840 4076416 - hypothetical protein gene gene4018 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20105 HW43_RS20110 HW43_25745 HW43_RS20110 4076720 4076983 - hypothetical protein gene gene4019 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20110 HW43_RS20115 HW43_19535 HW43_RS20115 4077090 4078835 - DNA helicase UvrD gene gene4020 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20115 HW43_RS20120 HW43_19540 HW43_RS20120 4079013 4079396 - hypothetical protein gene gene4021 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20120 HW43_RS20125 HW43_19545 HW43_RS20125 4080131 4080445 - hypothetical protein gene gene4022 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20125 HW43_RS20130 HW43_19550 HW43_RS20130 4080549 4080785 - hypothetical protein gene gene4023 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20130 HW43_RS20135 HW43_19555 HW43_RS20135 4080772 4081380 - adhesin/hemagglutinin gene gene4024 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20135 HW43_RS20140 HW43_19560 HW43_RS20140 4082483 4082674 + hypothetical protein gene gene4025 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20140 HW43_RS20145 HW43_19565 HW43_RS20145 4082727 4082960 - hypothetical protein gene gene4026 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20145 HW43_RS20150 HW43_19570 HW43_RS20150 4083056 4083679 - DNA-binding protein gene gene4027 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20150 HW43_RS20155 HW43_25750 HW43_RS20155 4083768 4084265 - hypothetical protein gene gene4028 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20155 HW43_RS20160 HW43_19575 HW43_RS20160 4084615 4085181 - hypothetical protein gene gene4029 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20160 HW43_RS20165 HW43_19580 HW43_RS20165 4085484 4085786 + transposase gene gene4030 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20165 HW43_RS20170 HW43_19585 HW43_RS20170 4085822 4086640 + transposase gene gene4031 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20170 HW43_RS20175 HW43_19590 HW43_RS20175 4086914 4087339 - hypothetical protein gene gene4032 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20175 HW43_RS20180 HW43_19595 HW43_RS20180 4087336 4087719 - hypothetical protein gene gene4033 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20180 HW43_RS20185 HW43_19600 HW43_RS20185 4087980 4088549 - hypothetical protein gene gene4034 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20185 HW43_RS20190 HW43_19605 HW43_RS20190 4088753 4088950 + hypothetical protein gene gene4035 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20190 HW43_RS20195 HW43_25755 HW43_RS20195 4089066 4089238 - hypothetical protein gene gene4036 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20195 HW43_RS20200 HW43_19610 HW43_RS20200 4089296 4089436 - hemolysin activation protein gene gene4037 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20200 HW43_RS20205 HW43_19615 HW43_RS20205 4090197 4090403 + Rha family transcriptional regulator gene gene4038 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20205 HW43_RS20210 HW43_25760 HW43_RS20210 4090490 4090774 + hypothetical protein gene gene4039 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20210 HW43_RS20215 HW43_19625 HW43_RS20215 4090847 4091158 + transposase gene gene4040 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20215 HW43_RS20220 HW43_25765 HW43_RS20220 4091171 4091353 + hypothetical protein gene gene4041 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20220 HW43_RS20225 HW43_19630 HW43_RS20225 4091347 4092024 + transposase gene gene4042 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20225 HW43_RS20230 HW43_25770 HW43_RS20230 4092012 4092353 + hypothetical protein gene gene4043 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20230 HW43_RS20235 HW43_19640 HW43_RS20235 4092675 4094159 - hypothetical protein gene gene4044 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20235 HW43_RS20240 HW43_19645 HW43_RS20240 4095389 4096261 + hypothetical protein gene gene4045 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20240 HW43_RS20245 HW43_19650 HW43_RS20245 4096589 4099708 + hypothetical protein gene gene4046 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20245 HW43_RS20250 HW43_19655 HW43_RS20250 4099829 4102345 + membrane protein gene gene4047 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20250 HW43_RS20255 HW43_19660 HW43_RS20255 4102421 4102876 + hypothetical protein gene gene4048 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20255 HW43_RS20260 HW43_19665 HW43_RS20260 4102955 4103188 + hypothetical protein gene gene4049 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20260 HW43_RS20265 HW43_19670 HW43_RS20265 4103288 4104106 + hypothetical protein gene gene4050 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20265 HW43_RS20270 HW43_19675 HW43_RS20270 4104161 4104646 + hypothetical protein gene gene4051 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20270 HW43_RS20275 HW43_19680 HW43_RS20275 4104662 4105138 + hypothetical protein gene gene4052 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20275 HW43_RS20280 HW43_19685 HW43_RS20280 4105201 4105422 + hypothetical protein gene gene4053 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20280 HW43_RS20285 HW43_25775 HW43_RS20285 4105422 4105535 + hypothetical protein gene gene4054 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20285 HW43_RS20290 HW43_19695 HW43_RS20290 4105585 4105959 + antitoxin gene gene4055 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20290 HW43_RS20295 HW43_19700 HW43_RS20295 4106006 4106383 + toxin gene gene4056 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20295 HW43_RS20300 HW43_19705 HW43_RS20300 4106380 4106868 + hypothetical protein gene gene4057 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20300 HW43_RS20305 HW43_19710 HW43_RS20305 4106880 4107077 + hypothetical protein gene gene4058 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20305 HW43_RS20310 HW43_19715 HW43_RS20310 4107162 4108004 + restriction methylase gene gene4059 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20310 HW43_RS20315 HW43_19720 HW43_RS20315 4108347 4108883 - general secretion pathway protein gene gene4060 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20315 HW43_RS20320 HW43_19725 HW43_RS20320 4108885 4110063 - type II secretion system protein GspL similar to general secretory pathway protein L gene gene4061 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20320 HW43_RS20325 HW43_19730 HW43_RS20325 4110060 4111037 - type II secretion system protein gene gene4062 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20325 HW43_RS20330 HW43_19735 HW43_RS20330 4111040 4111603 - type II secretion system protein GspJ gene gene4063 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20330 HW43_RS20335 HW43_19740 HW43_RS20335 4111636 4112007 - type II secretion system protein GspI gene gene4064 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20335 HW43_RS20340 HW43_19745 HW43_RS20340 4112004 4112567 - type II secretion system protein GspH gene gene4065 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20340 HW43_RS20345 HW43_19750 HW43_RS20345 4112571 4113026 - type II secretion system protein GspG gene gene4066 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20345 HW43_RS20350 HW43_19755 HW43_RS20350 4113043 4114266 - type II secretion system protein GspF gene gene4067 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20350 HW43_RS20355 HW43_19760 HW43_RS20355 4114266 4115759 - type II secretion system protein GspE gene gene4068 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20355 HW43_RS20360 HW43_19765 HW43_RS20360 4115759 4117819 - type II secretion system protein GspD gene gene4069 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20360 HW43_RS20365 HW43_19770 HW43_RS20365 4117849 4118808 - type II secretion system protein GspC part of the general (type II) secretion pathway (GSP)%2C a signal sequence-dependent process responsible for protein export%3B involved in trans-location of exoproteins from the cytoplasm to the periplasm gene gene4070 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20365 HW43_RS20370 HW43_19775 HW43_RS20370 4118826 4119236 - hypothetical protein gene gene4071 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20370 HW43_RS20375 HW43_19780 HW43_RS20375 4119302 4120111 - peptidase A24 gene gene4072 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20375 HW43_RS20380 HW43_19785 HW43_RS20380 4120251 4124819 - hypothetical protein gene gene4073 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20380 HW43_RS20385 HW43_19790 HW43_RS20385 4124970 4125179 + hypothetical protein gene gene4074 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20385 HW43_RS20390 HW43_25780 HW43_RS20390 4125305 4127006 - glycolate permease glcA gene gene4075 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20390 HW43_RS20395 HW43_19800 HW43_RS20395 4127362 4129533 - malate synthase G gene gene4076 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20395 HW43_RS20400 HW43_19805 HW43_RS20400 4129555 4129959 - protein GlcG gene gene4077 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20400 HW43_RS20405 HW43_19810 glcF glcF 4129964 4131187 - glycolate oxidase gene gene4078 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20405 HW43_RS20410 HW43_19815 glcE glcE 4131198 4132250 - FAD-binding protein gene gene4079 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20410 HW43_RS20415 HW43_19820 HW43_RS20415 4132250 4133749 - glycolate oxidase gene gene4080 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20415 HW43_RS20420 HW43_19825 HW43_RS20420 4134005 4134769 + glc operon transcriptional activator gene gene4081 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20420 HW43_RS20425 HW43_19830 HW43_RS20425 4134776 4135918 - DNA-binding protein gene gene4082 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20425 HW43_RS20430 HW43_19835 HW43_RS20430 4136322 4138010 + acyl-CoA synthetase activates fatty acids by binding to coenzyme A gene gene4083 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20430 HW43_RS20435 HW43_19840 HW43_RS20435 4138007 4138921 + short-chain dehydrogenase gene gene4084 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20435 HW43_RS20440 HW43_19845 HW43_RS20440 4138953 4139201 + hypothetical protein gene gene4085 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20440 HW43_RS20445 HW43_19850 HW43_RS20445 4139201 4140373 + 8-amino-7-oxononanoate synthase gene gene4086 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20445 HW43_RS20450 HW43_19855 HW43_RS20450 4140409 4141488 - LPS export ABC transporter permease LptG gene gene4087 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20450 HW43_RS20455 HW43_19860 HW43_RS20455 4141485 4142555 - LPS export ABC transporter permease LptF gene gene4088 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20455 HW43_RS20460 HW43_19865 HW43_RS20460 4142586 4143146 - transcriptional regulator gene gene4089 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20460 HW43_RS20465 HW43_19870 HW43_RS20465 4143158 4143982 - hypothetical protein gene gene4090 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20465 HW43_RS20470 HW43_19875 HW43_RS20470 4143982 4145331 - membrane protein gene gene4091 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20470 HW43_RS20475 HW43_19880 HW43_RS20475 4145377 4146135 - hypothetical protein gene gene4092 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20475 HW43_RS20480 HW43_19885 HW43_RS20480 4146167 4146865 - hypothetical protein gene gene4093 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20480 HW43_RS20485 HW43_19890 HW43_RS20485 4147054 4147746 + ATP-binding protein gene gene4094 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20485 HW43_RS20490 HW43_19895 HW43_RS20490 4147795 4149294 - phosphate transporter PitA involved in the transport of inorganic phosphate gene gene4095 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20490 HW43_RS20495 HW43_19900 HW43_RS20495 4149586 4151445 - bifunctional glutathionylspermidine synthetase/amidase catalyzes the formation of glutathionylspermidine from glutathione and spermidine%3B also catalyzes the reverse reaction gene gene4096 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20495 HW43_RS20500 HW43_19905 HW43_RS20500 4151650 4152516 + disulfide-bond oxidoreductase YghU YghU%3B B2989%3B one of eight putative glutathione transferase proteins from E. coli gene gene4097 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20500 HW43_RS20505 HW43_19910 HW43_RS20505 4152639 4152887 - hydrogenase-2 operon protein HybG gene gene4098 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20505 HW43_RS20510 HW43_19915 hypA hypA 4152900 4153241 - hydrogenase nickel incorporation protein plays a role in hydrogenase nickel cofactor insertion gene gene4099 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20510 HW43_RS20515 HW43_19920 HW43_RS20515 4153234 4153722 - hydrogenase-2 operon protein HybE gene gene4100 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20515 HW43_RS20520 HW43_19925 hybD hybD 4153715 4154209 - hydrogenase 2 maturation endopeptidase protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC) gene gene4101 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20520 HW43_RS20525 HW43_19930 HW43_RS20525 4154209 4155912 - hydrogenase-2 large chain involved in hydrogen uptake gene gene4102 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20525 HW43_RS20530 HW43_19935 HW43_RS20530 4155909 4157087 - Ni/Fe-hydrogenase b-type cytochrome subunit HybB%3B cytochrome b subunit of the hydrogenase 2 enzyme%2C composed of HybA%2C B%2C C%2C and O subunits gene gene4103 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20530 HW43_RS20535 HW43_19940 HW43_RS20535 4157077 4158063 - hydrogenase-2 operon protein HybA Fe-S ferrodoxin type component%3B participates in the periplasmic electron-transferring activity of hydrogenase 2 gene gene4104 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20535 HW43_RS20540 HW43_19945 HW43_RS20540 4158066 4159184 - hydrogenase-2 small chain involved in hydrogen uptake gene gene4105 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20540 HW43_RS20545 HW43_25785 HW43_RS20545 4159191 4159376 - hypothetical protein gene gene4106 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20545 HW43_RS20550 HW43_19950 HW43_RS20550 4159373 4159660 - hypothetical protein gene gene4107 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20550 HW43_RS20555 HW43_19955 HW43_RS20555 4159779 4160666 - dienelactone hydrolase gene gene4108 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20555 HW43_RS20560 HW43_19960 HW43_RS20560 4160823 4161863 + glyceraldehyde 3-phosphate reductase gene gene4109 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20560 HW43_RS20565 HW43_19965 HW43_RS20565 4161903 4162397 - hypothetical protein gene gene4110 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20565 HW43_RS20570 HW43_19970 HW43_RS20570 4162588 4163472 + oxidoreductase gene gene4111 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20570 HW43_RS20575 HW43_19975 HW43_RS20575 4163744 4164169 - biopolymer transporter ExbD membrane spanning protein in TonB-ExbB-ExbD complex%3B involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell gene gene4112 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20575 HW43_RS20580 HW43_19980 HW43_RS20580 4164176 4164910 - biopolymer transporter ExbB membrane spanning protein in TonB-ExbB-ExbD complex%3B involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell gene gene4113 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20580 HW43_RS20585 HW43_25790 HW43_RS20585 4164903 4165040 - membrane protein gene gene4114 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20585 HW43_RS20590 HW43_19990 HW43_RS20590 4165162 4166349 + cystathionine beta-lyase catalyzes the formation of L-homocysteine from cystathionine gene gene4115 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20590 HW43_RS20595 HW43_19995 HW43_RS20595 4166489 4167148 + hypothetical protein gene gene4116 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20595 HW43_RS20600 HW43_20000 HW43_RS20600 4167188 4168087 - AraC family transcriptional regulator gene gene4117 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20600 HW43_RS20605 HW43_25795 HW43_RS20605 4168084 4168230 - hypothetical protein gene gene4118 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20605 HW43_RS20610 HW43_20005 HW43_RS20610 4168281 4169444 + aldehyde reductase gene gene4119 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20610 HW43_RS20615 HW43_20010 dkgA dkgA 4169549 4170376 + 2%2C5-diketo-D-gluconic acid reductase A methylglyoxal reductase/beta-keto ester reductase%3B catalyzes the reduction of 2%2C5-diketo-D-gluconic acid to 2-keto-L-gulonic acid%3B also catalyzes the reduction of methylglyoxal%2C ethyl-2-methylacetoacetate and ethyl-acetoacetate gene gene4120 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20615 HW43_RS20620 HW43_20015 HW43_RS20620 4170576 4171502 + hypothetical protein gene gene4121 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20620 HW43_RS20625 HW43_20020 HW43_RS20625 4171553 4171810 + hypothetical protein gene gene4122 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20625 HW43_RS20630 HW43_20025 HW43_RS20630 4171853 4174072 - Radical SAM superfamily protein gene gene4123 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20630 HW43_RS20635 HW43_20030 HW43_RS20635 4174183 4175595 - cell division protein FtsI septal ring component that protects the divisome from stress gene gene4124 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20635 HW43_RS20640 HW43_20035 HW43_RS20640 4175670 4176407 - 1-acyl-sn-glycerol-3-phosphate acyltransferase catalyzes the formation of 1%2C2-diacyl-sn-glycerol 3-phosphate from 1-acyl-sn-glycerol 3-phosphate using either acyl-CoA or acyl-ACP gene gene4125 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20640 HW43_RS20645 HW43_20040 HW43_RS20645 4176640 4178898 - DNA topoisomerase 4 subunit A decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling gene gene4126 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20645 HW43_RS20650 HW43_20045 HW43_RS20650 4179444 4179926 - transcriptional regulator gene gene4127 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20650 HW43_RS20655 HW43_20050 HW43_RS20655 4179979 4180371 - hypothetical protein gene gene4128 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20655 HW43_RS20660 HW43_20055 HW43_RS20660 4180523 4181182 + two-component system response regulator response regulator in two-component regulatory system with QseC%3B regulates FlhCD which is the master regulator for flagella and motility genes gene gene4129 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20660 HW43_RS20665 HW43_20060 HW43_RS20665 4181179 4182528 + two-component system sensor histidine kinase gene gene4130 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20665 HW43_RS20670 HW43_20065 HW43_RS20670 4182574 4182906 - membrane protein gene gene4131 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20670 HW43_RS20675 HW43_20070 HW43_RS20675 4183225 4183806 + NADPH quinone reductase MdaB involved in drug resistance gene gene4132 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20675 HW43_RS20680 HW43_20075 HW43_RS20680 4183837 4184151 + quinol monooxygenase YgiN catalyzes the oxidation of menadiol to menadione gene gene4133 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20680 HW43_RS20685 HW43_20080 HW43_RS20685 4184199 4186091 - DNA topoisomerase 4 subunit B decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling gene gene4134 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20685 HW43_RS20690 HW43_20085 HW43_RS20690 4186120 4186701 - esterase Displays esterase activity toward palmitoyl-CoA and pNP-butyrate gene gene4135 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20690 HW43_RS20695 HW43_20090 HW43_RS20695 4186701 4187528 - 3'%2C5'-cyclic adenosine monophosphate phosphodiesterase CpdA gene gene4136 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20695 HW43_RS20700 HW43_20095 HW43_RS20700 4187553 4187975 - dehydrogenase gene gene4137 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20700 HW43_RS20705 HW43_20100 nudF nudF 4187976 4188605 - ADP-ribose pyrophosphatase ADP-sugar pyrophosphatase%3B catalyzes the formation of D-ribose 5-phosphate from ADP-ribose%3B can also act on ADP-mannose and ADP-glucose gene gene4138 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20705 HW43_RS20710 HW43_20105 tolC tolC 4188810 4190291 + outer membrane protein TolC trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules%3B functions with a number of efflux systems in the inner membrane to transport molecules out of the cell gene gene4139 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20710 HW43_RS20715 HW43_25800 HW43_RS20715 4190291 4190551 + hypothetical protein gene gene4140 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20715 HW43_RS20720 HW43_20110 HW43_RS20720 4190439 4191110 + membrane protein gene gene4141 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20720 HW43_RS20725 HW43_20115 HW43_RS20725 4191116 4192276 + hypothetical protein gene gene4142 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20725 HW43_RS20730 HW43_20120 HW43_RS20730 4192314 4193102 - LigB family dioxygenase seems to be involved in biofilm formation%3B in asymptomatic bacteriuria E. coli strains 83972 and VR50%2C the ygiD gene is upregulated during biofilm formation in urine gene gene4143 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20730 HW43_RS20735 HW43_20125 HW43_RS20735 4193245 4194018 + zinc transporter ZupT gene gene4144 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20735 HW43_RS20740 HW43_25805 HW43_RS20740 4194076 4194246 - hypothetical protein gene gene4145 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20740 HW43_RS20745 HW43_20135 ribB ribB 4194507 4195160 - 3%2C4-dihydroxy-2-butanone 4-phosphate synthase DHBP synthase%3B functions during riboflavin biosynthesis gene gene4146 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20745 HW43_RS20750 HW43_20140 HW43_RS20750 4195534 4195824 + hypothetical protein gene gene4147 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20750 HW43_RS20755 HW43_20145 HW43_RS20755 4196107 4196658 + fimbrial protein gene gene4148 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20755 HW43_RS20760 HW43_20150 HW43_RS20760 4196718 4199222 + fimbrial outer membrane usher protein StdB gene gene4149 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20760 HW43_RS20765 HW43_20155 HW43_RS20765 4199238 4199987 + fimbrial assembly protein PapD gene gene4150 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20765 HW43_RS20770 HW43_25810 HW43_RS20770 4199989 4201052 + hypothetical protein gene gene4151 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20770 HW43_RS20775 HW43_20170 HW43_RS20775 4201095 4201295 - glycogen synthase Involved in glycogen synthesis. May be involved in glycogen priming gene gene4152 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20775 HW43_RS20780 HW43_20175 HW43_RS20780 4201564 4202193 + membrane protein gene gene4153 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20780 HW43_RS20785 HW43_20180 HW43_RS20785 4202220 4203881 + membrane protein gene gene4154 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20785 HW43_RS20790 HW43_25815 HW43_RS20790 4203981 4204232 + hypothetical protein gene gene4155 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20790 HW43_RS20795 HW43_25820 HW43_RS20795 4204216 4204608 + hypothetical protein gene gene4156 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20795 HW43_RS20800 HW43_20185 HW43_RS20800 4204675 4206108 - bifunctional protein HldE catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D%2CD-heptose-1%2C7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D%2CD-heptose gene gene4157 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20800 HW43_RS20805 HW43_20190 HW43_RS20805 4206156 4208996 - bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase%3B also catalyzes the reverse reaction - deadenylation%3B adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme gene gene4158 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20805 HW43_RS20810 HW43_20195 HW43_RS20810 4209019 4210320 - hypothetical protein gene gene4159 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20810 HW43_RS20815 HW43_25825 HW43_RS20815 4210337 4210522 - hypothetical protein gene gene4160 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20815 HW43_RS20820 HW43_20200 HW43_RS20820 4210562 4211182 + hypothetical protein gene gene4161 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20820 HW43_RS20825 HW43_20205 HW43_RS20825 4211246 4212484 + multifunctional CCA protein gene gene4162 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20825 HW43_RS20830 HW43_20210 HW43_RS20830 4212647 4213468 - undecaprenyl-diphosphatase BacA%3B phosphatase activity in Escherichia coli not kinase%3B involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell gene gene4163 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20830 HW43_RS20835 HW43_20215 folB folB 4213558 4213926 - dihydroneopterin triphosphate 2'-epimerase catalyzes the conversion of 7%2C8-dihydroneopterin to 6-hydroxymethyl-7%2C8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin gene gene4164 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20835 HW43_RS20840 HW43_20220 HW43_RS20840 4214031 4214648 + glycerol-3-phosphate acyltransferase involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis%3B functions with PlsX gene gene4165 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20840 HW43_RS20845 HW43_20225 HW43_RS20845 4214661 4215593 - transcriptional activator TtdR gene gene4166 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20845 HW43_RS20850 HW43_20230 HW43_RS20850 4215803 4216711 + tartrate dehydratase subunit alpha Involved in the tartrate degradation pathway gene gene4167 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20850 HW43_RS20855 HW43_20235 HW43_RS20855 4216708 4217313 + L+-tartrate dehydratase subunit beta Involved in the tartrate degradation pathway gene gene4168 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20855 HW43_RS20860 HW43_20240 HW43_RS20860 4217361 4218824 + antiporter involved in the transport of citrate into the cell along with the export of succinate out of the cell gene gene4169 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20860 HW43_RS20865 HW43_20245 HW43_RS20865 4218867 4219880 - tRNA N6-adenosine threonylcarbamoyltransferase universal genome maintenance protein%3B Kae1/Qri7/OSGEP/YgjD family protein%3B in Archaea%2C some Kae1 are found as fusion proteins similar to two distinct proteins in yeast that are involved in the KEOPS complex%3B kinase associated endopeptidase 1 (Kae1) and a serine/threonine protein kinase (Bud32)%3B in Pyrococcus Kae1 has atypical AP endonuclease activity and inhibits the kinase activity of Bud32%3B the protein is essential in Escherichia coli and Bacillus subtilis gene gene4170 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20865 HW43_RS20870 HW43_20250 rpsU rpsU 4220118 4220333 + 30S ribosomal protein S21 a small basic protein that is one of the last in the subunit assembly%3B omission does not prevent assembly but the subunit is inactive%3B binds central domain of 16S rRNA gene gene4171 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20870 HW43_RS20875 HW43_20255 dnaG dnaG 4220444 4222189 + DNA primase synthesizes RNA primers at the replication forks gene gene4172 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20875 HW43_RS20880 HW43_20260 HW43_RS20880 4222384 4224225 + RNA polymerase sigma factor RpoD sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B this is the primary sigma factor of bacteria gene gene4173 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20880 HW43_RS20885 HW43_20265 HW43_RS20885 4224303 4224809 - G/U mismatch DNA glycosylase gene gene4174 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20885 HW43_RS20890 HW43_20270 HW43_RS20890 4224934 4225009 + tRNA-Met tRNA gene4175 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20890 HW43_RS20895 HW43_20275 HW43_RS20895 4225063 4225827 - NADPH-dependent ferric-chelate reductase gene gene4176 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20895 HW43_RS20900 HW43_20280 HW43_RS20900 4226104 4226727 + transcriptional regulator gene gene4177 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20900 HW43_RS20905 HW43_20285 HW43_RS20905 4226881 4228401 - aerotaxis receptor gene gene4178 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20905 HW43_RS20910 HW43_20290 HW43_RS20910 4228819 4230198 + putrescine aminotransferase catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate gene gene4179 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20910 HW43_RS20915 HW43_20295 HW43_RS20915 4230240 4230572 - methionyl-tRNA synthetase gene gene4180 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20915 HW43_RS20920 HW43_20300 HW43_RS20920 4230791 4231774 + transcriptional regulator gene gene4181 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20920 HW43_RS20925 HW43_20305 ebgA ebgA 4231958 4235050 + beta-D-galactosidase subunit alpha in Escherichia coli this is the second beta-galactosidase system gene gene4182 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20925 HW43_RS20930 HW43_20310 ebgC ebgC 4235047 4235496 + evolved beta-galactosidase subunit beta in Escherichia coli this is the second beta-galactosidase system gene gene4183 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20930 HW43_RS20935 HW43_20315 HW43_RS20935 4235559 4236992 + amino acid permease gene gene4184 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20935 HW43_RS20940 HW43_20320 HW43_RS20940 4237126 4238196 + periplasmic protein gene gene4185 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20940 HW43_RS20945 HW43_20325 HW43_RS20945 4238213 4240564 + alpha-glucosidase gene gene4186 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20945 HW43_RS20950 HW43_20330 HW43_RS20950 4240890 4242908 + 2%2C4-dienoyl-CoA reductase gene gene4187 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20950 HW43_RS20955 HW43_20335 HW43_RS20955 4242953 4243369 - antitoxin HigA gene gene4188 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20955 HW43_RS20960 HW43_25830 HW43_RS20960 4243366 4243536 - toxin RelE gene gene4189 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20960 HW43_RS20965 HW43_20340 HW43_RS20965 4243640 4244776 - 23S rRNA methyltransferase gene gene4190 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20965 HW43_RS20970 HW43_20345 HW43_RS20970 4244861 4245364 + hypothetical protein gene gene4191 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20970 HW43_RS20975 HW43_20350 HW43_RS20975 4245441 4246124 + hypothetical protein gene gene4192 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20975 HW43_RS20980 HW43_20355 HW43_RS20980 4246203 4247189 + oxidoreductase gene gene4193 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20980 HW43_RS20985 HW43_20360 HW43_RS20985 4247472 4248437 + hypothetical protein gene gene4194 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20985 HW43_RS20990 HW43_20365 HW43_RS20990 4248836 4250080 + serine/threonine transporter SstT involved in the import of serine and threonine coupled with the import of sodium gene gene4195 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20990 HW43_RS20995 HW43_20370 HW43_RS20995 4250085 4250636 - membrane protein gene gene4196 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS20995 HW43_RS21000 HW43_20375 HW43_RS21000 4250719 4252206 - altronate hydrolase gene gene4197 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21000 HW43_RS21005 HW43_20380 HW43_RS21005 4252221 4253633 - uronate isomerase catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate%3B functions in glucuronic and galacturonic metabolism gene gene4198 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21005 HW43_RS21010 HW43_20385 HW43_RS21010 4254116 4255414 + hexuronate transporter involved in the transport of aldohexuronates gene gene4199 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21010 HW43_RS21015 HW43_20390 HW43_RS21015 4255502 4256590 - minor pilin and initiator gene gene4200 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21015 HW43_RS21020 HW43_20395 HW43_RS21020 4256587 4259271 - fimbrial usher protein gene gene4201 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21020 HW43_RS21025 HW43_20400 HW43_RS21025 4259363 4259863 - fimbrial protein gene gene4202 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21025 HW43_RS21030 HW43_20405 HW43_RS21030 4259893 4260516 - fimbrial protein gene gene4203 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21030 HW43_RS21035 HW43_20410 HW43_RS21035 4260905 4261681 + exu regulon transcriptional regulator regulates the expression of uxuBA gene gene4204 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21035 HW43_RS21040 HW43_20415 HW43_RS21040 4262026 4262688 + hypothetical protein gene gene4205 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21040 HW43_RS21045 HW43_20420 HW43_RS21045 4262692 4263075 + modulator protein MzrA gene gene4206 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21045 HW43_RS21050 HW43_20425 HW43_RS21050 4263222 4263590 + hypothetical protein gene gene4207 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21050 HW43_RS21055 HW43_20430 HW43_RS21055 4263628 4263933 + hypothetical protein gene gene4208 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21055 HW43_RS21060 HW43_20435 HW43_RS21060 4263936 4264340 + hypothetical protein gene gene4209 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21060 HW43_RS21065 HW43_20440 HW43_RS21065 4264330 4264629 + hypothetical protein gene gene4210 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21065 HW43_RS21070 HW43_20445 HW43_RS21070 4264815 4265207 + membrane protein gene gene4211 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21070 HW43_RS21075 HW43_20450 HW43_RS21075 4265277 4266263 + hypothetical protein gene gene4212 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21075 HW43_RS21080 HW43_20455 HW43_RS21080 4266556 4266921 + hypothetical protein gene gene4213 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21080 HW43_RS21085 HW43_20460 HW43_RS21085 4267163 4267519 + membrane protein gene gene4214 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21085 HW43_RS21090 HW43_20465 HW43_RS21090 4267570 4268466 - LysR family transcriptional regulator gene gene4215 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21090 HW43_RS21095 HW43_20470 HW43_RS21095 4268571 4269272 + pirin-like protein YhaK gene gene4216 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21095 HW43_RS21100 HW43_25835 HW43_RS21100 4269292 4269459 + hypothetical protein gene gene4217 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21100 HW43_RS21105 HW43_20480 HW43_RS21105 4269671 4270981 - membrane protein gene gene4218 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21105 HW43_RS21110 HW43_20485 HW43_RS21110 4271009 4272340 - transporter gene gene4219 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21110 HW43_RS21115 HW43_20490 HW43_RS21115 4272615 4273979 - L-serine dehydratase catalyzes the formation of pyruvate from serine gene gene4220 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21115 HW43_RS21120 HW43_20495 HW43_RS21120 4274051 4274440 - reactive intermediate/imine deaminase has endoribonuclease activity on mRNA gene gene4221 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21120 HW43_RS21125 HW43_20500 HW43_RS21125 4274454 4276748 - PFL-like enzyme TdcE formate acetyltransferase%3B catalyzes the formation of formate and acetyl-CoA from pyruvate gene gene4222 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21125 HW43_RS21130 HW43_20505 HW43_RS21130 4276782 4277990 - propionate/acetate kinase catalyzes the formation of propanoyl phosphate from propanoate and ATP%3B TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism gene gene4223 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21130 HW43_RS21135 HW43_20510 HW43_RS21135 4278016 4279347 - threonine/serine transporter TdcC gene gene4224 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21135 HW43_RS21140 HW43_20515 HW43_RS21140 4279369 4280358 - L-threonine dehydratase catabolic TdcB catalyzes the formation of 2-oxobutanoate from L-threonine%3B catabolic gene gene4225 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21140 HW43_RS21145 HW43_20520 HW43_RS21145 4280457 4281395 - transcriptional regulator regulates the tdcABCDEFG operon which is involved in amino acid degradation gene gene4226 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21145 HW43_RS21150 HW43_25840 HW43_RS21150 4281584 4281928 + transcriptional regulator participates in controlling the expression of several structural genes for the enzyme threonine dehydratase%3B TdcR activates the tdcABCDEFG operon gene gene4227 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21150 HW43_RS21155 HW43_20525 HW43_RS21155 4282184 4282723 + hypothetical protein gene gene4228 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21155 HW43_RS21160 HW43_20530 HW43_RS21160 4282745 4283932 + hypothetical protein gene gene4229 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21160 HW43_RS21165 HW43_20535 HW43_RS21165 4284270 4285250 + transposase gene gene4230 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21165 HW43_RS21170 HW43_20540 HW43_RS21170 4285408 4286415 - hypothetical protein gene gene4231 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21170 HW43_RS21175 HW43_20545 HW43_RS21175 4286621 4287499 - protease gene gene4232 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21175 HW43_RS21180 HW43_20550 HW43_RS21180 4287508 4288503 - protease gene gene4233 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21180 HW43_RS21185 HW43_20555 HW43_RS21185 4288712 4289236 + SCP-2 sterol transfer family protein gene gene4234 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21185 HW43_RS21190 HW43_20560 HW43_RS21190 4289230 4289733 + N-acetyltransferase gene gene4235 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21190 HW43_RS21195 HW43_20565 HW43_RS21195 4289720 4290022 - nuclease gene gene4236 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21195 HW43_RS21200 HW43_20570 HW43_RS21200 4290073 4290516 + hypothetical protein gene gene4237 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21200 HW43_RS21205 HW43_25845 HW43_RS21205 4290496 4291013 - general stress protein gene gene4238 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21205 HW43_RS21210 HW43_20580 HW43_RS21210 4291141 4291776 + hypothetical protein gene gene4239 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21210 HW43_RS21215 HW43_20585 HW43_RS21215 4291849 4292889 + permease gene gene4240 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21215 HW43_RS21220 HW43_20590 HW43_RS21220 4293003 4293578 - hypothetical protein gene gene4241 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21220 HW43_RS21225 HW43_20595 HW43_RS21225 4293588 4294178 - DnaA initiator-associating protein DiaA Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein gene gene4242 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21225 HW43_RS21230 HW43_20600 HW43_RS21230 4294198 4294593 - hypothetical protein gene gene4243 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21230 HW43_RS21235 HW43_20605 HW43_RS21235 4294551 4296587 - penicillin-binding protein activator LpoA gene gene4244 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21235 HW43_RS21240 HW43_20610 HW43_RS21240 4296651 4297511 + ribosomal RNA small subunit methyltransferase I gene gene4245 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21240 HW43_RS21245 HW43_20615 HW43_RS21245 4297554 4298645 - fimbrial protein gene gene4246 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21245 HW43_RS21250 HW43_20620 HW43_RS21250 4298656 4301172 - type VII secretion system (T7SS)%2C usher family protein gene gene4247 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21250 HW43_RS21255 HW43_20625 HW43_RS21255 4301202 4301897 - fimbrial protein gene gene4248 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21255 HW43_RS21260 HW43_20630 HW43_RS21260 4301977 4302561 - fimbrial protein gene gene4249 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21260 HW43_RS21265 HW43_20635 HW43_RS21265 4302961 4303662 - galactosamine-6-phosphate isomerase gene gene4250 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21265 HW43_RS21270 HW43_20640 HW43_RS21270 4303717 4304508 - PTS N-acetylgalactosamine transporter subunit IID catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IID with IIC forms the translocation channel%3B involved in N-acetylgalactosamine transport gene gene4251 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21270 HW43_RS21275 HW43_20645 HW43_RS21275 4304498 4305301 - N-acetylgalactosamine permease IIC component 1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3Bprotein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake%3B involved in N-acetylgalactosamine transport gene gene4252 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21275 HW43_RS21280 HW43_20650 HW43_RS21280 4305340 4305816 - PTS N-acetylgalactosamine transporter subunit IIB catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake%3B involved in N-acetylgalactosamine transport gene gene4253 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21280 HW43_RS21285 HW43_20655 kbaY kbaY 4305983 4306843 - tagatose-1%2C6-bisphosphate aldolase catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1%2C6-bisphosphate%3B in enteric bacteria there are two D-tagatose 1%2C6-bisphosphate-specific aldolases: KbaY (also called AgaY)%2C involved in catabolism of N-acetyl-galactosamine and D-galactosamine%2C and GatY which is part of the galactitol catabolism pathway gene gene4254 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21285 HW43_RS21290 HW43_20660 HW43_RS21290 4306856 4308010 - aldose isomerase gene gene4255 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21290 HW43_RS21295 HW43_20665 HW43_RS21295 4308361 4309494 - N-acetylglucosamine-6-phosphate deacetylase gene gene4256 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21295 HW43_RS21300 HW43_20670 HW43_RS21300 4309491 4309925 - PTS N-acetylgalactosamine transporter subunit IIA catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IID with IIC forms the translocation channel%3B involved in N-acetylgalactosamine transport gene gene4257 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21300 HW43_RS21305 HW43_20675 HW43_RS21305 4309943 4310821 - PTS N-acetylgalactosamine transporter subunit IID catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IID with IIC forms the translocation channel%3B involved in N-acetylgalactosamine transport gene gene4258 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21305 HW43_RS21310 HW43_20680 HW43_RS21310 4310811 4311590 - PTS N-acetylgalactosamine transporter subunit IIC catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake%3Binvolved in N-acetylgalactosamine transport gene gene4259 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21310 HW43_RS21315 HW43_20685 HW43_RS21315 4311601 4312074 - PTS N-acetylgalactosamine transporter subunit IIB catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake%3B involved in N-acetylgalactosamine transport gene gene4260 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21315 HW43_RS21320 HW43_20690 HW43_RS21320 4312097 4313377 - tagatose-1%2C6-bisphosphate aldolase with KbaY catalyzes the formation of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate from tagatose-1%2C6-bisphosphate%3B subunit Z may act as a chaperone for the Y subunit gene gene4261 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21320 HW43_RS21325 HW43_20695 HW43_RS21325 4313626 4314435 + DeoR family transcriptional regulator transcriptional repressor for the agaZVWA and agaSYBCDI operons gene gene4262 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21325 HW43_RS21330 HW43_20700 HW43_RS21330 4314490 4314954 - toxin YhaV gene gene4263 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21330 HW43_RS21335 HW43_20705 HW43_RS21335 4314954 4315289 - antitoxin PrlF SohA%3B PrlF%3B involved in protein secretion%3B when overproduced or mutated%2C it induces growth defect and increased export of a reporter protein%3B a PrlF mutation induces the activity of the Lon protease%2C and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation gene gene4264 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21335 HW43_RS21340 HW43_20710 garD garD 4315438 4317009 - galactarate dehydratase catalyzes the formation of 5-dehydro-4-deoxy-D-glucarate from D-galactarate gene gene4265 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21340 HW43_RS21350 HW43_20720 HW43_RS21350 4317384 4318718 + galactarate transporter gene gene4266 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21350 HW43_RS21355 HW43_20725 HW43_RS21355 4318734 4319504 + 5-keto-4-deoxy-D-glucarate aldolase cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate gene gene4267 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21355 HW43_RS21360 HW43_20730 garR garR 4319534 4320424 + 2-hydroxy-3-oxopropionate reductase catalyzes the reduction of tartronate semialdehyde to glycerate gene gene4268 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21360 HW43_RS21365 HW43_20735 HW43_RS21365 4320521 4321666 + glycerate kinase gene gene4269 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21365 HW43_RS21370 HW43_20760 HW43_RS21370 4322650 4323630 - transposase gene gene4270 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21370 HW43_RS21375 HW43_20765 HW43_RS21375 4323889 4325133 - tryptophan permease tryptophan transporter of high affinity gene gene4271 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21375 HW43_RS21380 HW43_25850 HW43_RS21380 4325149 4325286 + hypothetical protein gene gene4272 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21380 HW43_RS21385 HW43_20770 HW43_RS21385 4325287 4327176 - DEAD/DEAH box family ATP-dependent RNA helicase participates in the assembly of the large subunit of the ribosome%3B plays a key role in optimal cell growth at low temperature and is required for normal cell division gene gene4273 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21385 HW43_RS21390 HW43_20775 HW43_RS21390 4327356 4328240 - lipoprotein NlpI lipoprotein that appears to be involved in cell division%3B interacts with the periplasmic protease Prc and may be activated by protease processing gene gene4274 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21390 HW43_RS21395 HW43_20780 HW43_RS21395 4328349 4330484 - polyribonucleotide nucleotidyltransferase gene gene4275 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21395 HW43_RS21400 HW43_20785 HW43_RS21400 4330731 4331000 - 30S ribosomal protein S15 gene gene4276 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21400 HW43_RS21405 HW43_20790 truB truB 4331149 4332093 - tRNA pseudouridine synthase B catalyzes isomerization of specific uridines in RNA to pseudouridine%3B responsible for residues in T loops of many tRNAs gene gene4277 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21405 HW43_RS21410 HW43_20795 rbfA rbfA 4332093 4332494 - ribosome-binding factor A associates with free 30S ribosomal subunits%3B essential for efficient processing of 16S rRNA%3B in Escherichia coli rbfA is induced by cold shock gene gene4278 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21410 HW43_RS21415 HW43_20800 infB infB 4332658 4335330 - translation initiation factor IF-2 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex gene gene4279 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21415 HW43_RS21420 HW43_20805 nusA nusA 4335355 4336842 - transcription termination/antitermination protein NusA modifies transcription through interactions with RNA polymerase affecting elongation%2C readthrough%2C termination%2C and antitermination gene gene4280 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21420 HW43_RS21425 HW43_20810 HW43_RS21425 4336870 4337322 - ribosome maturation factor RimP required for the maturation of the 30S ribosomal subunits gene gene4281 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21425 HW43_RS21430 HW43_20815 HW43_RS21430 4337529 4337605 - tRNA-Met tRNA gene4282 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21430 HW43_RS21435 HW43_20820 HW43_RS21435 4337953 4339296 + argininosuccinate synthase catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis gene gene4283 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21435 HW43_RS21440 HW43_20825 HW43_RS21440 4339304 4340821 - phosphate starvation-inducible protein PsiE gene gene4284 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21440 HW43_RS21445 HW43_20830 HW43_RS21445 4341388 4341474 - tRNA-Leu tRNA gene4285 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21445 HW43_RS21450 HW43_20835 secG secG 4341489 4341821 - preprotein translocase subunit SecG gene gene4286 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21450 HW43_RS21455 HW43_20840 glmM glmM 4342049 4343386 - phosphoglucosamine mutase catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate gene gene4287 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21455 HW43_RS21460 HW43_20845 folP folP 4343379 4344227 - dihydropteroate synthase catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7%2C8-dihydropteridine diphosphate and 4-aminobenzoate gene gene4288 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21460 HW43_RS21465 HW43_20850 hflB hflB 4344317 4346251 - ATP-dependent zinc metalloprotease FtsH inner membrane metalloprotease%3B may be involved in degradation of aberrant cytoplasmic and membrane proteins gene gene4289 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21465 HW43_RS21470 HW43_20855 rrmJ rrmJ 4346351 4346980 - ribosomal RNA large subunit methyltransferase E Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit gene gene4290 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21470 HW43_RS21475 HW43_20860 HW43_RS21475 4347106 4347399 + RNA-binding protein RNA binding protein found associated to pre-50S subunit of the ribosome%3B putative role in ribosome assembly%3B necessary for optimal growth but not cell viability gene gene4291 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21475 HW43_RS21480 HW43_20865 greA greA 4347555 4348031 - transcription elongation factor GreA necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites%3B arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus gene gene4292 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21480 HW43_RS21485 HW43_20870 HW43_RS21485 4348279 4349712 + D-alanyl-D-alanine carboxypeptidase penicillin binding protein 4%3B penicillin sensitive%3B catalyzes the formation of D-alanine from D-alanyl-D-alanine%3B one of four%2C DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains gene gene4293 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21485 HW43_RS21490 HW43_20875 obgE obgE 4349752 4350924 - GTPase Obg ObgE%3B essential GTPase%3B exhibits high exchange rate for GTP/GDP%3B associates with 50S ribosomal subunit%3B involved in regulation of chromosomal replication gene gene4294 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21490 HW43_RS21495 HW43_20880 HW43_RS21495 4350940 4351905 - transporter gene gene4295 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21495 HW43_RS21500 HW43_20885 rpmA rpmA 4352032 4352289 - 50S ribosomal protein L27 involved in the peptidyltransferase reaction during translation gene gene4296 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21500 HW43_RS21505 HW43_20890 rplU rplU 4352310 4352621 - 50S ribosomal protein L21 gene gene4297 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21505 HW43_RS21510 HW43_20895 HW43_RS21510 4352880 4353851 + octaprenyl-diphosphate synthase gene gene4298 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21510 HW43_RS21515 HW43_20900 HW43_RS21515 4354079 4354357 + sugar fermentation stimulation protein B activator of maltose metabolism genes gene gene4299 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21515 HW43_RS21520 HW43_20905 HW43_RS21520 4354405 4355664 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene4300 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21520 HW43_RS21525 HW43_20910 HW43_RS21525 4355719 4355973 - acid stress protein IbaG gene gene4301 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21525 HW43_RS21530 HW43_20915 HW43_RS21530 4356133 4356426 - phospholipid ABC transporter-binding protein gene gene4302 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21530 HW43_RS21535 HW43_20920 HW43_RS21535 4356426 4357061 - phospholipid-binding protein involved in maintaining outer membrane lipid asymmetry gene gene4303 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21535 HW43_RS21540 HW43_20925 HW43_RS21540 4357080 4357631 - outer membrane lipid asymmetry maintenance protein MlaD gene gene4304 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21540 HW43_RS21545 HW43_20930 HW43_RS21545 4357636 4358418 - phospholipid ABC transporter permease gene gene4305 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21545 HW43_RS21550 HW43_20935 HW43_RS21550 4358426 4359235 - organic solvent ABC transporter ATP-binding protein ABC transporter maintaining outer membrane lipid asymmetry gene gene4306 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21550 HW43_RS21555 HW43_20940 HW43_RS21555 4359445 4360422 + sodium:proton antiporter YrbG%3B inner membrane protein involved in cell envelope integrity%3B putative sodium ion/calcium ion exchanger%3B in E. coli it is non essential for cell viability%3B member of the YRBG family of cation/Ca2+ exchangers gene gene4307 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21555 HW43_RS21560 HW43_20945 HW43_RS21560 4360436 4361422 + arabinose 5-phosphate isomerase KdsD gene gene4308 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21560 HW43_RS21565 HW43_20950 HW43_RS21565 4361443 4362009 + 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC forms homotetramers%3B catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate%3B functions in lipopolysaccharide biosynthesis gene gene4309 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21565 HW43_RS21570 HW43_20955 HW43_RS21570 4362006 4362581 + LPS export ABC transporter periplasmic protein LptC gene gene4310 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21570 HW43_RS21575 HW43_20960 HW43_RS21575 4362550 4363107 + LPS export system protein LptA LptA%3B periplasmic binding protein part of a putative ABC superfamily of uptake transporters%3B interacts with LptB protein%2C the ATP binding component of the uptake system gene gene4311 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21575 HW43_RS21580 HW43_20965 HW43_RS21580 4363114 4363839 + LPS export ABC transporter ATP-binding protein gene gene4312 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21580 HW43_RS21585 HW43_20970 HW43_RS21585 4363887 4365320 + RNA polymerase sigma-54 factor sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism%3B the rhizobia often have 2 copies of this sigma factor%3B in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation%3B in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions%2C rpoN1 gene was regulated in response to oxygen gene gene4313 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21585 HW43_RS21590 HW43_20975 HW43_RS21590 4365343 4365630 + ribosome hibernation promoting factor YhbH%3B resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase%3B binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization)%3B seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing gene gene4314 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21590 HW43_RS21595 HW43_20980 HW43_RS21595 4365748 4366239 + nitrogen regulatory protein involved in nitrogen metabolism%3B protein IIA is phosphorylated by enzyme I(Ntr) gene gene4315 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21595 HW43_RS21600 HW43_20985 HW43_RS21600 4366285 4367139 + glmZ(sRNA)-inactivating NTPase glucosamine-6-phosphate regulated%3B inactivates the glmS upregulator glmZ gene gene4316 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21600 HW43_RS21605 HW43_20990 HW43_RS21605 4367136 4367408 + phosphocarrier protein NPr gene gene4317 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21605 HW43_RS21610 HW43_20995 HW43_RS21610 4367622 4368254 + hypothetical protein gene gene4318 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21610 HW43_RS21615 HW43_21000 mtgA mtgA 4368251 4368979 - monofunctional biosynthetic peptidoglycan transglycosylase glycosyltransferase%3B polymerizes glycan strands in the peptidoglycan gene gene4319 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21615 HW43_RS21620 HW43_21005 HW43_RS21620 4368976 4369629 - isoprenoid biosynthesis protein gene gene4320 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21620 HW43_RS21625 HW43_21010 HW43_RS21625 4369859 4372195 - PAS domain-containing two-component system sensor histidine kinase/response regulator sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon%3B hybrid sensory histidine kinase in two-component regulatory system with ArcA gene gene4321 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21625 HW43_RS21630 HW43_21015 HW43_RS21630 4372291 4373220 - radical SAM protein gene gene4322 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21630 HW43_RS21635 HW43_21025 gltB gltB 4373895 4378355 + glutamate synthase subunit alpha catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate gene gene4323 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21635 HW43_RS21640 HW43_21030 HW43_RS21640 4378368 4379786 + glutamate synthase gene gene4324 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21640 HW43_RS21645 HW43_21035 HW43_RS21645 4379970 4381097 + hypothetical protein gene gene4325 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21645 HW43_RS21650 HW43_21040 HW43_RS21650 4381157 4381621 - DUF386 domain-containing protein gene gene4326 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21650 HW43_RS21655 HW43_21045 HW43_RS21655 4381618 4382493 - N-acetylmannosamine kinase catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein gene gene4327 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21655 HW43_RS21660 HW43_21050 HW43_RS21660 4382490 4383179 - N-acetylmannosamine-6-P epimerase Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate gene gene4328 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21660 HW43_RS21665 HW43_21055 HW43_RS21665 4383227 4384717 - sialic acid transporter gene gene4329 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21665 HW43_RS21670 HW43_21060 HW43_RS21670 4384826 4385719 - N-acetylneuraminate lyase catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid gene gene4330 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21670 HW43_RS21675 HW43_21065 HW43_RS21675 4385841 4386632 - transcriptional regulator NanR Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization gene gene4331 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21675 HW43_RS21680 HW43_21070 HW43_RS21680 4387012 4388379 + C4-dicarboxylate ABC transporter YhcL%3B uncharacterized member of the DcuC family of anaerobic dicarboxylate transporters%3B probable role in transport of carboxylates across the inner membrane from the periplasm%3B its encoding gene is not essential for growth and is probably cryptic gene gene4332 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21680 HW43_RS21685 HW43_21075 HW43_RS21685 4388422 4388919 - stringent starvation protein B gene gene4333 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21685 HW43_RS21690 HW43_21080 sspA sspA 4388925 4389563 - stringent starvation protein A transcriptional activator%3B required for activation of bacteriophage P1 late promoter%3B induced by starvation gene gene4334 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21690 HW43_RS21695 HW43_21085 HW43_RS21695 4389958 4390350 - 30S ribosomal protein S9 gene gene4335 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21695 HW43_RS21700 HW43_21090 HW43_RS21700 4390366 4390794 - 50S ribosomal protein L13 gene gene4336 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21700 HW43_RS21705 HW43_21095 HW43_RS21705 4391013 4392140 - ATPase gene gene4337 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21705 HW43_RS21710 HW43_21100 HW43_RS21710 4392334 4392732 + hypothetical protein gene gene4338 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21710 HW43_RS21715 HW43_21105 HW43_RS21715 4392886 4394253 + periplasmic pH-dependent serine endoprotease DegQ gene gene4339 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21715 HW43_RS21720 HW43_21110 HW43_RS21720 4394343 4395410 + serine endoprotease DegS gene gene4340 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21720 HW43_RS21725 HW43_21115 HW43_RS21725 4395473 4396411 - malate dehydrogenase oxidizes malate to oxaloacetate gene gene4341 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21725 HW43_RS21730 HW43_21120 HW43_RS21730 4396846 4397316 + arginine repressor regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes gene gene4342 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21730 HW43_RS21735 HW43_21125 HW43_RS21735 4397681 4397944 + membrane protein gene gene4343 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21735 HW43_RS21740 HW43_21130 HW43_RS21740 4398000 4398272 - barnase inhibitor gene gene4344 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21740 HW43_RS21745 HW43_21135 HW43_RS21745 4398364 4400331 - p-hydroxybenzoic acid efflux pump subunit AaeB with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate gene gene4345 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21745 HW43_RS21750 HW43_21140 HW43_RS21750 4400337 4401269 - p-hydroxybenzoic acid efflux pump subunit AaeA with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid%2C 6-hydroxy-2-naphthoic and 2-hydroxycinnamate gene gene4346 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21750 HW43_RS21755 HW43_21145 HW43_RS21755 4401277 4401480 - protein AaeX membrane protein AaeX%3B the gene is a member of the aaeXAB operon gene gene4347 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21755 HW43_RS21760 HW43_21150 HW43_RS21760 4401663 4402592 + HTH-type transcriptional activator AaeR for aaeXAB operon gene gene4348 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21760 HW43_RS21765 HW43_21155 tldD tldD 4402726 4404171 - protease TldD responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17%2C an exported protein that targets the essential topoisomerase II DNA gyrase%3B degrades the E. coli plasmid F-encoded CcdA gene gene4349 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21765 HW43_RS21770 HW43_21160 HW43_RS21770 4404601 4408401 - membrane protein gene gene4350 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21770 HW43_RS21775 HW43_21165 HW43_RS21775 4408469 4409938 - ribonuclease G involved in the processing of the 5'end of 16S rRNA gene gene4351 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21775 HW43_RS21780 HW43_21170 HW43_RS21780 4409928 4410521 - septum formation inhibitor Maf Maf%3B overexpression in Bacillus subtilis inhibits septation in the dividing cell gene gene4352 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21780 HW43_RS21785 HW43_21175 HW43_RS21785 4410530 4411018 - rod shape-determining protein MreD part of cell wall structural complex MreBCD%3B transmembrane component gene gene4353 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21785 HW43_RS21790 HW43_21180 HW43_RS21790 4411018 4412121 - rod shape-determining protein MreC in some organisms this protein is a transmembrane protein while in others it is periplasmic%3B involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall gene gene4354 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21790 HW43_RS21795 HW43_21185 HW43_RS21795 4412187 4413230 - rod shape-determining protein MreB gene gene4355 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21795 HW43_RS21800 HW43_25855 HW43_RS21800 4413338 4413526 + hypothetical protein gene gene4356 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21800 HW43_RS21805 HW43_21190 HW43_RS21805 4413535 4415475 - hypothetical protein regulates the degradation of the small RNAs CsrB and CsrC%3B may function to targate RNase E to specific RNA molecules gene gene4357 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21805 HW43_RS21810 HW43_21195 HW43_RS21810 4415627 4416601 + acrylyl-CoA reductase AcuI gene gene4358 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21810 HW43_RS21815 HW43_25860 HW43_RS21815 4416659 4416760 - hypothetical protein gene gene4359 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21815 HW43_RS21820 HW43_25865 HW43_RS21820 4416887 4417006 + hypothetical protein gene gene4360 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21820 HW43_RS21825 HW43_25870 HW43_RS21825 4417010 4417174 + hypothetical protein gene gene4361 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21825 HW43_RS21830 HW43_21200 HW43_RS21830 4417579 4418049 + acetyl-CoA carboxylase biotin carboxyl carrier protein subunit composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex%2C the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%2C which in turn controls the rate of fatty acid metabolism gene gene4362 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21830 HW43_RS21835 HW43_21205 HW43_RS21835 4418060 4419409 + acetyl-CoA carboxylase biotin carboxylase subunit an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase%2C an enzyme that catalyzes the formation of malonyl-CoA%2C which in turn controls the rate of fatty acid metabolism gene gene4363 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21835 HW43_RS21840 HW43_21210 HW43_RS21840 4419518 4419760 + membrane protein gene gene4364 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21840 HW43_RS21845 HW43_21215 panF panF 4419750 4421201 + sodium/pantothenate symporter mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions%3B member of SSS family of sodium/solute symporters%3B the imported panthothenate is phosphorylated by panthothenate kinase gene gene4365 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21845 HW43_RS21850 HW43_21220 prmA prmA 4421213 4422094 + ribosomal protein L11 methyltransferase methylates ribosomal protein L11 at multiple amino acid positions%3B mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype gene gene4366 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21850 HW43_RS21855 HW43_21225 HW43_RS21855 4422423 4423388 + tRNA-dihydrouridine synthase B gene gene4367 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21855 HW43_RS21860 HW43_21230 fis fis 4423414 4423710 + Fis family transcriptional regulator Stimulates excision of phage lambda%3B affects Mu development%3B acts as an activator of rRNA and iRNA transcription gene gene4368 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21860 HW43_RS21865 HW43_21235 HW43_RS21865 4423796 4424680 + DNA adenine methyltransferase YhdJ gene gene4369 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21865 HW43_RS21870 HW43_21240 HW43_RS21870 4424764 4424943 + hypothetical protein gene gene4370 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21870 HW43_RS21875 HW43_21245 HW43_RS21875 4424946 4425608 - acrEF/envCD operon repressor gene gene4371 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21875 HW43_RS21880 HW43_21250 HW43_RS21880 4426007 4427164 + MexX family efflux pump subunit with AcrD and TolC forms a transport system involved in resistance to a number of compounds including lipophilic antibiotics gene gene4372 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21880 HW43_RS21885 HW43_21255 HW43_RS21885 4427176 4430280 + multidrug efflux RND transporter permease subunit gene gene4373 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21885 HW43_RS21890 HW43_25875 HW43_RS21890 4430308 4430427 - hypothetical protein gene gene4374 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21890 HW43_RS21895 HW43_21260 HW43_RS21895 4430533 4430754 + membrane protein gene gene4375 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21895 HW43_RS21900 HW43_25880 HW43_RS21900 4430980 4431156 + hypothetical protein gene gene4376 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21900 HW43_RS21905 HW43_21270 HW43_RS21905 4431185 4432210 + amino acid ABC transporter substrate-binding protein gene gene4377 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21905 HW43_RS21910 HW43_21275 HW43_RS21910 4432278 4433459 + amino acid ABC transporter permease gene gene4378 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21910 HW43_RS21915 HW43_21280 HW43_RS21915 4433469 4434572 + amino acid ABC transporter permease gene gene4379 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21915 HW43_RS21920 HW43_21285 HW43_RS21920 4434580 4435338 + arginine ABC transporter ATP-binding protein gene gene4380 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21920 HW43_RS21925 HW43_21290 HW43_RS21925 4435401 4435516 - 5S ribosomal RNA rRNA gene4381 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21925 HW43_RS21930 HW43_21295 HW43_RS21930 4435556 4435631 - tRNA-Thr tRNA gene4382 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21930 HW43_RS21935 HW43_21300 HW43_RS21935 4435646 4435761 - 5S ribosomal RNA rRNA gene4383 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21935 HW43_RS21940 HW43_21305 HW43_RS21940 4435844 4438768 - 23S ribosomal RNA rRNA gene4384 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21940 HW43_RS21945 HW43_21310 HW43_RS21945 4438943 4439018 - tRNA-Ala tRNA gene4385 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21945 HW43_RS21950 HW43_21315 HW43_RS21950 4439061 4439137 - tRNA-Ile tRNA gene4386 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21950 HW43_RS21955 HW43_21320 HW43_RS21955 4439194 4440749 - 16S ribosomal RNA rRNA gene4387 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21955 HW43_RS21960 HW43_21330 HW43_RS21960 4441220 4441774 + hypothetical protein gene gene4388 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21960 HW43_RS21965 HW43_21335 HW43_RS21965 4441750 4442007 - DUF1488 domain-containing protein gene gene4389 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21965 HW43_RS21970 HW43_21340 HW43_RS21970 4442004 4442822 - shikimate dehydrogenase (NADP+) gene gene4390 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21970 HW43_RS21975 HW43_21345 HW43_RS21975 4442827 4443399 - threonylcarbamoyl-AMP synthase involved in the biosynthesis of the threonylcarbamoyladenosine (t6A) residue at position 37 of ANN-decoding tRNAs gene gene4391 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21975 HW43_RS21980 HW43_21350 HW43_RS21980 4443404 4443946 - hypothetical protein gene gene4392 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21980 HW43_RS21985 HW43_21355 HW43_RS21985 4443975 4444448 - protein Smg gene gene4393 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21985 HW43_RS21990 HW43_21360 HW43_RS21990 4444420 4445544 - hypothetical protein gene gene4394 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21990 HW43_RS21995 HW43_21365 HW43_RS21995 4445674 4446183 + peptide deformylase gene gene4395 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS21995 HW43_RS22000 HW43_21370 fmt fmt 4446198 4447145 + methionyl-tRNA formyltransferase modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation%3B inactivation of this gene in Escherichia coli severely impairs growth gene gene4396 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22000 HW43_RS22005 HW43_21375 HW43_RS22005 4447191 4448480 + 16S rRNA methyltransferase catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA%3B SAM-dependent methyltransferase gene gene4397 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22005 HW43_RS22010 HW43_21380 trkA trkA 4448502 4449878 + trk system potassium uptake protein trkA involved in potassium uptake%3B found to be peripherally associated with the inner membrane in Escherichia coli%3B contains an NAD-binding domain gene gene4398 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22010 HW43_RS22015 HW43_21385 mscL mscL 4450008 4450418 + large-conductance mechanosensitive channel forms homopentamer%3B channel that opens in response to pressure or hypoosmotic shock gene gene4399 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22015 HW43_RS22020 HW43_21390 HW43_RS22020 4450415 4450633 - ribosome-rescue factor A gene gene4400 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22020 HW43_RS22025 HW43_21395 zntR zntR 4450689 4451114 - transcriptional regulator mediates expression of the zinc export protein ZntA in response to high levels of zinc%3B member of MerR family of transcriptional regulators gene gene4401 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22025 HW43_RS22030 HW43_21400 HW43_RS22030 4451125 4451493 - hypothetical protein gene gene4402 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22030 HW43_RS22035 HW43_21405 rplQ rplQ 4451600 4451983 - 50S ribosomal protein L17 is a component of the macrolide binding site in the peptidyl transferase center gene gene4403 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22035 HW43_RS22040 HW43_21410 HW43_RS22040 4452024 4453013 - DNA-directed RNA polymerase subunit alpha catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme gene gene4404 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22040 HW43_RS22045 HW43_21415 HW43_RS22045 4453039 4453659 - 30S ribosomal protein S4 gene gene4405 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22045 HW43_RS22050 HW43_21420 HW43_RS22050 4453693 4454082 - 30S ribosomal protein S11 gene gene4406 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22050 HW43_RS22055 HW43_21425 HW43_RS22055 4454099 4454455 - 30S ribosomal protein S13 gene gene4407 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22055 HW43_RS22060 HW43_21430 HW43_RS22060 4454602 4454718 - 50S ribosomal protein L36 gene gene4408 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22060 HW43_RS22065 HW43_21435 secY secY 4454750 4456081 - protein translocase subunit SecY forms heterotrimeric complex in the membrane%3B in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG%3B the SecG subunit is not essential%3B in bacteria translocation is driven via the SecA ATPase gene gene4409 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22065 HW43_RS22070 HW43_21440 HW43_RS22070 4456089 4456523 - 50S ribosomal protein L15 gene gene4410 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22070 HW43_RS22075 HW43_21445 rpmD rpmD 4456527 4456706 - 50S ribosomal protein L30 L30 binds domain II of the 23S rRNA and the 5S rRNA%3B similar to eukaryotic protein L7 gene gene4411 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22075 HW43_RS22080 HW43_21450 HW43_RS22080 4456710 4457213 - 30S ribosomal protein S5 gene gene4412 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22080 HW43_RS22085 HW43_21455 HW43_RS22085 4457228 4457581 - 50S ribosomal protein L18 gene gene4413 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22085 HW43_RS22090 HW43_21460 HW43_RS22090 4457591 4458124 - 50S ribosomal protein L6 gene gene4414 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22090 HW43_RS22095 HW43_21465 HW43_RS22095 4458137 4458529 - 30S ribosomal protein S8 gene gene4415 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22095 HW43_RS22100 HW43_21470 rpsN rpsN 4458563 4458868 - 30S ribosomal protein S14 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit%3B similar to what is observed with proteins L31 and L33%2C some proteins in this family contain CXXC motifs that are involved in zinc binding%3B if two copies are present in a genome%2C then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc%3B the proteins in this group do not appear to have the zinc-binding motif gene gene4416 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22100 HW43_RS22105 HW43_21475 HW43_RS22105 4458883 4459422 - 50S ribosomal protein L5 gene gene4417 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22105 HW43_RS22110 HW43_21480 rplX rplX 4459437 4459751 - 50S ribosomal protein L24 assembly initiator protein%3B binds to 5' end of 23S rRNA and nucleates assembly of the 50S%3B surrounds polypeptide exit tunnel gene gene4418 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22110 HW43_RS22115 HW43_21485 HW43_RS22115 4459762 4460133 - 50S ribosomal protein L14 gene gene4419 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22115 HW43_RS22120 HW43_21490 HW43_RS22120 4460298 4460552 - 30S ribosomal protein S17 gene gene4420 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22120 HW43_RS22125 HW43_21495 HW43_RS22125 4460552 4460743 - 50S ribosomal protein L29 one of the stabilizing components for the large ribosomal subunit gene gene4421 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22125 HW43_RS22130 HW43_21500 HW43_RS22130 4460743 4461153 - 50S ribosomal protein L16 gene gene4422 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22130 HW43_RS22135 HW43_21505 HW43_RS22135 4461166 4461867 - 30S ribosomal protein S3 gene gene4423 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22135 HW43_RS22140 HW43_21510 HW43_RS22140 4461885 4462217 - 50S ribosomal protein L22 gene gene4424 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22140 HW43_RS22145 HW43_21515 HW43_RS22145 4462232 4462510 - 30S ribosomal protein S19 gene gene4425 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22145 HW43_RS22150 HW43_21520 HW43_RS22150 4462527 4463348 - 50S ribosomal protein L2 gene gene4426 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22150 HW43_RS22155 HW43_21525 rplW rplW 4463366 4463668 - 50S ribosomal protein L23 binds third domain of 23S rRNA and protein L29%3B part of exit tunnel gene gene4427 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22155 HW43_RS22160 HW43_21530 rplD rplD 4463665 4464270 - 50S ribosomal protein L4 L4 is important during the early stages of 50S assembly%3B it initially binds near the 5' end of the 23S rRNA gene gene4428 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22160 HW43_RS22165 HW43_21535 HW43_RS22165 4464281 4464910 - 50S ribosomal protein L3 gene gene4429 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22165 HW43_RS22170 HW43_21540 rpsJ rpsJ 4464943 4465254 - 30S ribosomal protein S10 NusE%3B involved in assembly of the 30S subunit%3B in the ribosome%2C this protein is involved in the binding of tRNA%3B in Escherichia coli this protein was also found to be involved in transcription antitermination%3B NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination%3B binding of NusB/S10 to boxA nucleates assembly of the antitermination complex gene gene4430 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22170 HW43_RS22175 HW43_25885 HW43_RS22175 4465383 4465544 - hypothetical protein gene gene4431 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22175 HW43_RS22180 HW43_21545 HW43_RS22180 4465633 4466100 + peptidase A24 gene gene4432 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22180 HW43_RS22185 HW43_21550 HW43_RS22185 4466097 4466573 - bacterioferritin iron storage protein gene gene4433 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22185 HW43_RS22190 HW43_21555 HW43_RS22190 4466646 4466840 - bacterioferritin-associated ferredoxin gene gene4434 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22190 HW43_RS22195 HW43_21560 tuf tuf 4467023 4468207 - translation elongation factor EF-Tu 1 EF-Tu%3B promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B when the tRNA anticodon matches the mRNA codon%2C GTP hydrolysis results%3B the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts%3B many prokaryotes have two copies of the gene encoding EF-Tu gene gene4435 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22195 HW43_RS22200 HW43_21565 fusA fusA 4468278 4470392 - elongation factor G EF-G%3B promotes GTP-dependent translocation of the ribosome during translation%3B many organisms have multiple copies of this gene gene gene4436 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22200 HW43_RS22205 HW43_21570 HW43_RS22205 4470489 4470959 - 30S ribosomal protein S7 gene gene4437 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22205 HW43_RS22210 HW43_21575 HW43_RS22210 4471056 4471430 - 30S ribosomal protein S12 gene gene4438 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22210 HW43_RS22215 HW43_21580 HW43_RS22215 4471556 4471843 - protein TusB in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs gene gene4439 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22215 HW43_RS22220 HW43_21585 HW43_RS22220 4471851 4472210 - protein TusC in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur transfer that results in thiouridation to U34 position in some tRNAs gene gene4440 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22220 HW43_RS22225 HW43_21590 HW43_RS22225 4472210 4472596 - sulfurtransferase TusD in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs gene gene4441 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22225 HW43_RS22230 HW43_21595 HW43_RS22230 4472596 4473318 - transcriptional regulator gene gene4442 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22230 HW43_RS22235 HW43_21600 HW43_RS22235 4473485 4474297 - FKBP-type peptidyl-prolyl cis-trans isomerase rotamase gene gene4443 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22235 HW43_RS22240 HW43_21605 HW43_RS22240 4474518 4474736 + protein SlyX required for phi X174 lysis gene gene4444 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22240 HW43_RS22245 HW43_21610 HW43_RS22245 4474785 4475375 - FKBP-type peptidyl-prolyl cis-trans isomerase rotamase gene gene4445 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22245 HW43_RS22250 HW43_21615 HW43_RS22250 4475470 4475670 - hypothetical protein gene gene4446 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22250 HW43_RS22255 HW43_21620 HW43_RS22255 4475680 4477485 - glutathione-regulated potassium-efflux system protein KefB involved in potassium efflux gene gene4447 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22255 HW43_RS22260 HW43_21625 HW43_RS22260 4477485 4478036 - potassium transporter required for KefB activity gene gene4448 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22260 HW43_RS22265 HW43_21630 HW43_RS22265 4478167 4480080 + ABC transporter ATP-binding protein gene gene4449 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22265 HW43_RS22270 HW43_21635 HW43_RS22270 4480080 4481102 + hydrolase gene gene4450 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22270 HW43_RS22275 HW43_21640 HW43_RS22275 4481096 4481314 + hypothetical protein gene gene4451 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22275 HW43_RS22280 HW43_21645 HW43_RS22280 4481368 4482237 + phosphoribulokinase gene gene4452 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22280 HW43_RS22285 HW43_21650 HW43_RS22285 4482292 4482696 - hypothetical protein gene gene4453 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22285 HW43_RS22290 HW43_25890 HW43_RS22290 4482776 4482991 + hypothetical protein gene gene4454 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22290 HW43_RS22295 HW43_21655 HW43_RS22295 4482998 4483630 + cAMP-activated global transcriptional regulator CRP cAMP receptor protein%3B complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons gene gene4455 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22295 HW43_RS22300 HW43_21660 HW43_RS22300 4483681 4485771 + membrane protein gene gene4456 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22300 HW43_RS22305 HW43_21665 argD argD 4485838 4487058 - succinyldiaminopimelate aminotransferase DapATase%3B bifunctional enzyme that functions in arginine and lysine biosynthetic pathways%3B catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2%2C6-diaminoheptanedioate gene gene4457 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22305 HW43_RS22310 HW43_21670 HW43_RS22310 4487144 4487707 - aminodeoxychorismate synthase TrpG%3B with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine%3B TrpG provides the glutamine amidotransferase activity gene gene4458 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22310 HW43_RS22315 HW43_21675 HW43_RS22315 4487739 4488341 - cell filamentation protein Fic gene gene4459 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22315 HW43_RS22320 HW43_25895 HW43_RS22320 4488331 4488498 - hypothetical protein gene gene4460 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22320 HW43_RS22325 HW43_21685 HW43_RS22325 4488603 4489175 - peptidyl-prolyl cis-trans isomerase gene gene4461 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22325 HW43_RS22330 HW43_21690 HW43_RS22330 4489446 4490627 + protein TsgA gene gene4462 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22330 HW43_RS22335 HW43_21695 HW43_RS22335 4490889 4493432 + nitrite reductase subunit NirD gene gene4463 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22335 HW43_RS22340 HW43_21700 nirD nirD 4493429 4493755 + nitrite reductase (NADH) small subunit involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+%3B bounds to NirB%2C the cytoplasmic subunit%2C whose expression is induced at high nitrate concentrations gene gene4464 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22340 HW43_RS22345 HW43_21705 HW43_RS22345 4493882 4494688 + nitrite transporter NirC member of the FNT family of formate and nitrite transporters gene gene4465 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22345 HW43_RS22350 HW43_21710 cysG cysG 4494707 4496080 + siroheme synthase multifunction enzyme consisting of uroporphyrin-III C-methyltransferase%2C precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase%3B catalyzes the methylation of uroporphyrinogen III to form precorrin-2%2C then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin gene gene4466 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22350 HW43_RS22355 HW43_21715 HW43_RS22355 4496327 4496494 + lipoprotein gene gene4467 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22355 HW43_RS22360 HW43_21720 HW43_RS22360 4496601 4497686 - hypothetical protein gene gene4468 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22360 HW43_RS22365 HW43_21725 HW43_RS22365 4497698 4499002 - membrane protein gene gene4469 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22365 HW43_RS22370 HW43_21730 HW43_RS22370 4499014 4499367 - membrane protein gene gene4470 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22370 HW43_RS22375 HW43_21735 HW43_RS22375 4499378 4500256 - hydrolase phosphotriesterase homology protein%3B PhP%3B YhfV%3B member of a family of proteins related to phosphotriesterase (PTE) gene gene4471 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22375 HW43_RS22380 HW43_21740 HW43_RS22380 4500253 4501479 - mutase gene gene4472 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22380 HW43_RS22385 HW43_21745 HW43_RS22385 4501479 4502642 - hypothetical protein gene gene4473 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22385 HW43_RS22390 HW43_21750 HW43_RS22390 4502726 4503088 - PRD domain protein gene gene4474 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22390 HW43_RS22395 HW43_21755 HW43_RS22395 4503105 4504010 - hypothetical protein gene gene4475 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22395 HW43_RS22400 HW43_21760 HW43_RS22400 4504279 4505283 - tryptophanyl-tRNA synthetase gene gene4476 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22400 HW43_RS22405 HW43_21765 HW43_RS22405 4505276 4506034 - phosphoglycolate phosphatase catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate gene gene4477 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22405 HW43_RS22410 HW43_21770 HW43_RS22410 4506027 4506704 - ribulose-phosphate 3-epimerase gene gene4478 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22410 HW43_RS22415 HW43_21775 HW43_RS22415 4506722 4507558 - DNA adenine methylase gene gene4479 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22415 HW43_RS22420 HW43_21780 HW43_RS22420 4507665 4508951 - cell division protein DamX binds the septal ring gene gene4480 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22420 HW43_RS22425 HW43_21785 aroB aroB 4509043 4510131 - 3-dehydroquinate synthase catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate%3B functions in aromatic amino acid biosynthesis gene gene4481 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22425 HW43_RS22430 HW43_21790 aroK aroK 4510188 4510709 - shikimate kinase type I enzyme similar to type II but differentially regulated%3B major shikimate kinase in fully repressed cells%3B catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis gene gene4482 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22430 HW43_RS22435 HW43_21795 hofQ hofQ 4511110 4512270 - porin outer membrane porin probably involved in uptake of extracellular double-stranded DNA%3B similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa gene gene4483 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22435 HW43_RS22440 HW43_25900 HW43_RS22440 4512260 4512664 - DNA utilization protein HofP gene gene4484 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22440 HW43_RS22445 HW43_21805 HW43_RS22445 4512654 4513094 - DNA utilization protein HofO gene gene4485 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22445 HW43_RS22450 HW43_21810 HW43_RS22450 4513078 4513617 - DNA utilization protein HofN gene gene4486 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22450 HW43_RS22455 HW43_21815 HW43_RS22455 4513617 4514396 - DNA utilization protein HofM gene gene4487 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22455 HW43_RS22460 HW43_21820 mrcA mrcA 4514516 4517068 + penicillin-binding protein 1A bifunctional murein transglycosylase/murein transpeptidase%3B penicillin-binding protein 1A%3B involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation%3B penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits gene gene4488 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22460 HW43_RS22465 HW43_21825 nudE nudE 4517233 4517793 - ADP compounds hydrolase NudE ADP-sugar pyrophosphatase%3B catalyzes the formation of D-ribose 5-phosphate from ADP-ribose%3B can also act on ADP-mannose and ADP-glucose gene gene4489 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22465 HW43_RS22470 HW43_21830 HW43_RS22470 4518113 4520248 + intracellular growth attenuator protein IgaA gene gene4490 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22470 HW43_RS22475 HW43_21835 HW43_RS22475 4520313 4520981 + GMP/IMP nucleotidase YrfG gene gene4491 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22475 HW43_RS22480 HW43_21840 HW43_RS22480 4520992 4521393 + heat-shock protein 15 gene gene4492 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22480 HW43_RS22485 HW43_21845 hslO hslO 4521418 4522296 + heat-shock protein Hsp33 becomes active under oxidative stress%3B four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive%3B oxidative stress results in oxidized cysteines%2C release of zinc%2C and binding of Hsp33 to aggregation-prone proteins%3B forms dimers and higher order oligomers gene gene4493 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22485 HW43_RS22490 HW43_21850 HW43_RS22490 4522431 4524155 - membrane protein gene gene4494 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22490 HW43_RS22495 HW43_25905 HW43_RS22495 4524231 4524362 - hypothetical protein gene gene4495 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22495 HW43_RS22500 HW43_21855 HW43_RS22500 4524534 4526156 + phosphoenolpyruvate carboxykinase [ATP] PEP carboxykinase%3B PEP carboxylase%3B PEPCK%3B catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP gene gene4496 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22500 HW43_RS22505 HW43_21860 envZ envZ 4526232 4527584 - two-component system sensor histidine kinase membrane-localized osmosensor%3B histidine kinase%3B in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR gene gene4497 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22505 HW43_RS22510 HW43_21865 ompR ompR 4527581 4528300 - two-component system response regulator part of two-component system EnvZ/OmpR%3B regulates transcription of outer membrane porin genes ompC/F%3B under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR%3B the result is increased expression of ompC and repression of ompF%3B also functions in regulation of other genes%3B forms dimers upon phosphorylation gene gene4498 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22510 HW43_RS22515 HW43_21870 greB greB 4528528 4529004 + transcription elongation factor GreB necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites%3B arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus gene gene4499 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22515 HW43_RS22520 HW43_21875 HW43_RS22520 4529101 4531422 + transcription accessory protein gene gene4500 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22520 HW43_RS22525 HW43_21880 feoA feoA 4531860 4532087 + iron transporter gene gene4501 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22525 HW43_RS22530 HW43_21885 feoB feoB 4532104 4534425 + iron transporter cytoplasmic membrane ferrous uptake system permease%3B mutations disrupt the ability of Escherichia coli to take up ferrous iron%3B GTP-binding protein which requires GTP for efficient iron(II) uptake gene gene4502 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22530 HW43_RS22535 HW43_21890 HW43_RS22535 4534425 4534661 + ferrous iron transporter C regulatory protein that controls transcription of feoABC genes gene gene4503 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22535 HW43_RS22540 HW43_21895 HW43_RS22540 4534864 4535742 + transposase gene gene4504 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22540 HW43_RS22545 HW43_21900 HW43_RS22545 4535771 4536541 - pimeloyl-[acyl-carrier protein] methyl ester esterase Shows carboxylesterase activity with a preference for short chain fatty acid esters%3B involved in pimeloyl-CoA synthesis gene gene4505 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22545 HW43_RS22550 HW43_21905 HW43_RS22550 4536579 4537262 + protein GntX required for utilization of DNA as the sole source of carbon and energy gene gene4506 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22550 HW43_RS22555 HW43_21910 HW43_RS22555 4537321 4537896 + fe/S biogenesis protein nfuA cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source gene gene4507 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22555 HW43_RS22560 HW43_21915 HW43_RS22560 4538257 4539573 + gluconate transporter gene gene4508 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22560 HW43_RS22565 HW43_21920 malQ malQ 4539618 4541702 - 4-alpha-glucanotransferase amylomaltase%3B acts to release glucose from maltodextrins gene gene4509 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22565 HW43_RS22570 HW43_21925 HW43_RS22570 4541712 4544105 - maltodextrin phosphorylase gene gene4510 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22570 HW43_RS22575 HW43_21930 HW43_RS22575 4544717 4547422 + transcriptional regulator Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides gene gene4511 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22575 HW43_RS22580 HW43_21935 HW43_RS22580 4547465 4548481 - RNA 3'-terminal phosphate cyclase catalyzes the conversion of terminal3'-phosphate of RNA to the 2'%2C3'-cyclicphosphodiester gene gene4512 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22580 HW43_RS22585 HW43_21940 HW43_RS22585 4548485 4549711 - RNA-splicing ligase gene gene4513 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22585 HW43_RS22590 HW43_21945 HW43_RS22590 4549900 4551498 + Fis family transcriptional regulator sigma 54-dependent%3B regulates genes involved in forming a 2'%2C3'-cyclic phosphodiester on RNA gene gene4514 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22590 HW43_RS22595 HW43_21950 HW43_RS22595 4551480 4552238 - glycerol-3-phosphate regulon repressor represses the glpD%2C glpFK%2C glpTQ%2C and glpACB operons involved in glycerol-3-phosphate metabolism gene gene4515 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22595 HW43_RS22600 HW43_21955 HW43_RS22600 4552255 4553085 - rhomboid protease GlpG protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity gene gene4516 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22600 HW43_RS22605 HW43_21960 glpE glpE 4553130 4553456 - thiosulfate sulfurtransferase GlpE belongs to rhodanese family%3B thiosulfate thiotransferase%3B in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency%3B contains an active site cysteine gene gene4517 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22605 HW43_RS22610 HW43_21965 glpD glpD 4553646 4555151 + glycerol-3-phosphate dehydrogenase in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions%3B anaerobic expression is repressed by the arcAB system%3B converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8%3B associates with the cytoplasmic membrane gene gene4518 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22610 HW43_RS22615 HW43_21970 HW43_RS22615 4555205 4555810 - membrane protein gene gene4519 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22615 HW43_RS22620 HW43_21975 HW43_RS22620 4555813 4556580 - hypothetical protein gene gene4520 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22620 HW43_RS22625 HW43_21980 HW43_RS22625 4556583 4557293 - hypothetical protein gene gene4521 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22625 HW43_RS22630 HW43_21985 HW43_RS22630 4557309 4558814 - ABC transporter ATP-binding protein gene gene4522 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22630 HW43_RS22635 HW43_21990 HW43_RS22635 4558942 4561389 - glycogen phosphorylase gene gene4523 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22635 HW43_RS22640 HW43_21995 glgA glgA 4561408 4562841 - glycogen synthase catalyzes the formation of alpha-1%2C4-glucan chains from ADP-glucose gene gene4524 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22640 HW43_RS22645 HW43_22000 glgC glgC 4562841 4564136 - glucose-1-phosphate adenylyltransferase catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate gene gene4525 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22645 HW43_RS22650 HW43_22005 HW43_RS22650 4564154 4566127 - glycogen debranching protein catalyzes the hydrolysis of the alpha-1%2C6-glucosidic linkages in partially depolymerized glycogen gene gene4526 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22650 HW43_RS22655 HW43_22010 HW43_RS22655 4566124 4568310 - 1%2C4-alpha-glucan-branching protein gene gene4527 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22655 HW43_RS22660 HW43_22015 HW43_RS22660 4568583 4569686 - aspartate-semialdehyde dehydrogenase catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde gene gene4528 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22660 HW43_RS22665 HW43_22020 HW43_RS22665 4569879 4570472 + membrane protein gene gene4529 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22665 HW43_RS22670 HW43_22025 HW43_RS22670 4570518 4571720 - DNA processing protein DprA gene gene4530 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22670 HW43_RS22675 HW43_22030 HW43_RS22675 4571720 4573816 - ATP-dependent DNA helicase RecQ gene gene4531 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22675 HW43_RS22680 HW43_22035 HW43_RS22680 4573969 4575309 - low-affinity gluconate transporter gene gene4532 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22680 HW43_RS22685 HW43_22040 gntK gntK 4575313 4575840 - thermoresistant gluconokinase thermoresistant%3B catalyzes the formation of 6-phospho-D-gluconate from gluconate gene gene4533 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22685 HW43_RS22690 HW43_22045 HW43_RS22690 4575979 4576974 - transcriptional regulator gene gene4534 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22690 HW43_RS22695 HW43_22050 HW43_RS22695 4577198 4577893 - quercetin 2%2C3-dioxygenase gene gene4535 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22695 HW43_RS22700 HW43_22055 HW43_RS22700 4578016 4579053 - oxidoreductase gene gene4536 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22700 HW43_RS22705 HW43_25910 HW43_RS22705 4579385 4579873 + aminoacyl nucleotide detoxifying acetyltransferase YhhY%3B regulated by the fur regulator%3B unknown function gene gene4537 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22705 HW43_RS22710 HW43_22065 HW43_RS22710 4580110 4581288 + hypothetical protein gene gene4538 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22710 HW43_RS22715 HW43_22070 HW43_RS22715 4581285 4581779 + hypothetical protein gene gene4539 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22715 HW43_RS22720 HW43_22075 HW43_RS22720 4582229 4582513 + heat-shock protein gene gene4540 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22720 HW43_RS22725 HW43_22080 ggt ggt 4582551 4584293 - gamma-glutamyltranspeptidase periplasmic enzyme%3B post-translationally processed into two subunits which are required for wild-type enzyme activity%3B cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides gene gene4541 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22725 HW43_RS22730 HW43_22085 HW43_RS22730 4584413 4584853 + DUF2756 domain-containing protein gene gene4542 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22730 HW43_RS22735 HW43_22090 ugpQ ugpQ 4584840 4585583 - glycerophosphodiester phosphodiesterase hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol%3B induced when cells are starved for inorganic phosphate gene gene4543 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22735 HW43_RS22740 HW43_22095 ugpC ugpC 4585580 4586650 - glycerol-3-phosphate ABC transporter ATP-binding protein part of the UgpABCE glycerol-3-phosphate uptake system gene gene4544 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22740 HW43_RS22745 HW43_22100 HW43_RS22745 4586652 4587497 - glycerol-3-phosphate transporter membrane protein with UgpABC is involved in uptake of glycerol-3-phosphate gene gene4545 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22745 HW43_RS22750 HW43_22105 HW43_RS22750 4587494 4588381 - glycerol-3-phosphate transporter permease with UgpEC is involved in the uptake of glycerol-3-phosphate gene gene4546 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22750 HW43_RS22755 HW43_22110 HW43_RS22755 4588479 4589795 - glycerol-3-phosphate ABC transporter substrate-binding protein with UgpACE is involved in the uptake of glycerol-3-phosphate gene gene4547 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22755 HW43_RS22760 HW43_25915 HW43_RS22760 4590027 4590155 - hypothetical protein gene gene4548 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22760 HW43_RS22765 HW43_22115 livF livF 4590191 4590904 - branched-chain amino acid ABC transporter ATP-binding protein with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system%3B LivFGHMK is specific for the transport of leucine%2C while LivFGHMJ is a transporter for leucine%2C isoleucine%2C and valine gene gene4549 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22765 HW43_RS22770 HW43_22120 livG livG 4590906 4591673 - branched-chain amino acid ABC transporter ATP-binding protein Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids%3B LivFGHMK is specific for the transport of leucine%2C while LivFGHMJ is a transporter for leucine%2C isoleucine%2C and valine gene gene4550 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22770 HW43_RS22775 HW43_22125 livM livM 4591670 4592947 - leucine/isoleucine/valine transporter permease subunit Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids%3B LivFGHMK is specific for the transport of leucine%2C while LivFGHMJ is a transporter for leucine%2C isoleucine%2C and valine gene gene4551 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22775 HW43_RS22780 HW43_22130 HW43_RS22780 4592944 4593870 - branched-chain amino acid ABC transporter permease LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter gene gene4552 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22780 HW43_RS22785 HW43_22135 HW43_RS22785 4593918 4595027 - leucine-specific-binding protein with LivFGHM is involved in the high affinity leucine transport gene gene4553 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22785 HW43_RS22790 HW43_22140 HW43_RS22790 4595451 4595834 + hypothetical protein gene gene4554 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22790 HW43_RS22795 HW43_25920 HW43_RS22795 4595858 4595977 + hypothetical protein gene gene4555 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22795 HW43_RS22800 HW43_22145 HW43_RS22800 4596033 4597151 - amino acid ABC transporter substrate-binding protein with LivFGHM is involved in the high affinity leucine transport gene gene4556 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22800 HW43_RS22805 HW43_22150 HW43_RS22805 4597407 4598261 - RNA polymerase sigma factor RpoH binds with the catalytic core of RNA polymerase to produce the holoenzyme%3B this sigma factor is responsible for the expression of heat shock promoters gene gene4557 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22805 HW43_RS22810 HW43_22155 ftsX ftsX 4598506 4599564 - cell division protein FtsX ABC transporter%2C membrane protein gene gene4558 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22810 HW43_RS22815 HW43_22160 HW43_RS22815 4599557 4600225 - cell division ATP-binding protein FtsE ATP-binding protein of an ATP-binding cassette transporter%3B when bound to FtsX%2C FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions gene gene4559 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22815 HW43_RS22820 HW43_22165 HW43_RS22820 4600228 4601721 - signal recognition particle-docking protein FtsY cell division protein%3B signal recognition protein receptor%3B functions in the targeting and insertion of membrane proteins gene gene4560 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22820 HW43_RS22825 HW43_22170 rsmD rsmD 4601871 4602467 + ribosomal RNA small subunit methyltransferase D catalyzes the methylation of 16S rRNA at position G966 gene gene4561 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22825 HW43_RS22830 HW43_22175 HW43_RS22830 4602457 4602726 + membrane protein gene gene4562 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22830 HW43_RS22835 HW43_22180 HW43_RS22835 4602729 4603088 - hypothetical protein gene gene4563 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22835 HW43_RS22840 HW43_22185 HW43_RS22840 4603229 4603855 + membrane protein gene gene4564 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22840 HW43_RS22845 HW43_22190 zntA zntA 4603929 4606127 + cadmium-transporting ATPase P-type ATPase involved in the export of lead%2C cadmium%2C zinc and mercury gene gene4565 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22845 HW43_RS22850 HW43_22195 HW43_RS22850 4606229 4606474 - sulfurtransferase TusA TusA%3B transfers sulfur to TusBCD complex%3B involved in thiouridation of U34 position of some tRNAs gene gene4566 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22850 HW43_RS22855 HW43_22200 HW43_RS22855 4606695 4607360 + hypothetical protein gene gene4567 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22855 HW43_RS22860 HW43_22205 HW43_RS22860 4607433 4607990 + protein DcrB gene gene4568 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22860 HW43_RS22865 HW43_22210 HW43_RS22865 4607994 4609211 - MFS transporter gene gene4569 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22865 HW43_RS22870 HW43_22215 HW43_RS22870 4609343 4610392 + pheromone autoinducer 2 transporter gene gene4570 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22870 HW43_RS22875 HW43_22220 HW43_RS22875 4610447 4611034 + 4'-phosphopantetheinyl transferase gene gene4571 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22875 HW43_RS22880 HW43_22225 HW43_RS22880 4611145 4612719 + nickel ABC transporter substrate-binding protein gene gene4572 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22880 HW43_RS22885 HW43_22230 HW43_RS22885 4612719 4613663 + nickel ABC transporter permease with NikACDE is involved in nickel transport into the cell gene gene4573 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22885 HW43_RS22890 HW43_22235 nikC nikC 4613660 4614493 + nickel ABC transporter permease with NikABDE is involved in nickel transport into the cell gene gene4574 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22890 HW43_RS22895 HW43_22240 nikD nikD 4614493 4615257 + nickel ABC transporter ATP-binding protein with NikABCE is involved in nickel transport into the cell gene gene4575 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22895 HW43_RS22900 HW43_22245 nikE nikE 4615254 4616060 + nickel ABC transporter ATP-binding protein with NikABCD is involved with nickel transport into the cell gene gene4576 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22900 HW43_RS22905 HW43_22250 HW43_RS22905 4616066 4616467 + nickel-responsive regulator Inhibits transcription at high concentrations of nickel gene gene4577 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22905 HW43_RS22910 HW43_22255 HW43_RS22910 4616587 4616946 - DNA repair protein HhH-GPD gene gene4578 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22910 HW43_RS22915 HW43_25925 HW43_RS22915 4616943 4617173 - hexulose-6-phosphate synthase gene gene4579 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22915 HW43_RS22920 HW43_22260 HW43_RS22920 4617277 4618401 - inner membrane transport permease YhhJ gene gene4580 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22920 HW43_RS22925 HW43_22265 HW43_RS22925 4618401 4621136 - multidrug ABC transporter ATP-binding protein gene gene4581 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22925 HW43_RS22930 HW43_22270 HW43_RS22930 4621133 4622200 - membrane protein gene gene4582 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22930 HW43_RS22935 HW43_22275 HW43_RS22935 4622566 4624188 - hypothetical protein gene gene4583 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22935 HW43_RS22940 HW43_25930 HW43_RS22940 4624450 4626038 - hypothetical protein gene gene4584 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22940 HW43_RS22945 HW43_25935 HW43_RS22945 4626057 4626209 - hypothetical protein gene gene4585 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22945 HW43_RS22950 HW43_25940 HW43_RS22950 4626351 4626449 - hypothetical protein gene gene4586 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22950 HW43_RS22955 HW43_22285 HW43_RS22955 4626466 4627473 + membrane protein gene gene4587 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22955 HW43_RS22960 HW43_22295 HW43_RS22960 4627789 4628991 - membrane protein gene gene4588 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22960 HW43_RS22965 HW43_22300 HW43_RS22965 4629223 4630722 + Low-affinity inorganic phosphate transporter 1 involved in the transport of inorganic phosphate gene gene4589 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22965 HW43_RS22970 HW43_22305 HW43_RS22970 4630793 4631128 - universal stress protein B ppGpp-dependent%2C membrane associated%2C stress protein produced under conditions of nutrient deprivation%2C osmotic shock and oxidative stress gene gene4590 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22970 HW43_RS22975 HW43_22310 HW43_RS22975 4631519 4631953 + universal stress protein A involved in resistance to DNA-damaging agents gene gene4591 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22975 HW43_RS22980 HW43_22315 tppB tppB 4632270 4633739 + dipeptide and tripeptide permease B mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium%3B member of proton-dependent oligopeptide transport (POT) system family%3B in Escherichia coli this gene is regulated by OmpR although not via osmoregulation gene gene4592 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22980 HW43_RS22985 HW43_22320 HW43_RS22985 4633788 4634540 - methyltransferase predicted SAM-dependent methyltransferase gene gene4593 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22985 HW43_RS22990 HW43_22325 HW43_RS22990 4634548 4636590 - oligopeptidase A gene gene4594 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22990 HW43_RS22995 HW43_22330 HW43_RS22995 4636793 4637635 + hypothetical protein gene gene4595 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS22995 HW43_RS23000 HW43_22335 HW43_RS23000 4637707 4639059 + glutathione reductase catalyzes the reduction of 2 glutathione to glutathione disulfide%3B maintains high levels of reduced glutathione in the cytosol%3B involved in redox regulation and oxidative defense gene gene4596 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23000 HW43_RS23005 HW43_25945 HW43_RS23005 4639113 4639229 - hypothetical protein gene gene4597 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23005 HW43_RS23010 HW43_25950 HW43_RS23010 4639224 4639397 + hypothetical protein gene gene4598 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23010 HW43_RS23015 HW43_22345 HW43_RS23015 4639936 4640289 + arsenical resistance operon repressor regulates the expression of of the arsRBC involved in resistance to arsenic gene gene4599 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23015 HW43_RS23020 HW43_22350 HW43_RS23020 4640343 4641632 + arsenical pump membrane protein gene gene4600 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23020 HW43_RS23025 HW43_22355 HW43_RS23025 4641645 4642070 + arsenate reductase gene gene4601 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23025 HW43_RS23030 HW43_22360 HW43_RS23030 4642193 4642489 - ArsR family transcriptional regulator gene gene4602 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23030 HW43_RS23035 HW43_22365 HW43_RS23035 4642597 4643598 + transporter gene gene4603 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23035 HW43_RS23040 HW43_25955 HW43_RS23040 4644179 4645401 + hypothetical protein gene gene4604 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23040 HW43_RS23045 HW43_22375 HW43_RS23045 4645648 4646214 + outer membrane protein slp gene gene4605 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23045 HW43_RS23050 HW43_22380 HW43_RS23050 4646370 4646900 + transcriptional regulator gene gene4606 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23050 HW43_RS23055 HW43_22385 HW43_RS23055 4646942 4647589 - magnesium transporter ATPase gene gene4607 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23055 HW43_RS23060 HW43_22390 hdeB hdeB 4647653 4647979 - acid stress chaperone HdeB gene gene4608 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23060 HW43_RS23065 HW43_22395 HW43_RS23065 4648095 4648427 - acid stress chaperone HdeA inactive form gene gene4609 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23065 HW43_RS23070 HW43_22400 HW43_RS23070 4648682 4649254 + protein HdeD gene gene4610 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23070 HW43_RS23075 HW43_22405 HW43_RS23075 4650053 4650580 + transcriptional regulator GadE gene gene4611 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23075 HW43_RS23080 HW43_22410 HW43_RS23080 4650581 4650859 - hypothetical protein gene gene4612 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23080 HW43_RS23085 HW43_22415 HW43_RS23085 4650919 4652076 + multidrug resistance protein MdtE gene gene4613 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23085 HW43_RS23090 HW43_22420 HW43_RS23090 4652101 4655214 + multidrug efflux RND transporter permease subunit gene gene4614 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23090 HW43_RS23095 HW43_22425 HW43_RS23095 4655577 4656305 - AraC family transcriptional regulator gene gene4615 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23095 HW43_RS23100 HW43_22430 HW43_RS23100 4656673 4657497 - AraC family transcriptional regulator regulates genes in response to acid and/or during stationary phase gene gene4616 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23100 HW43_RS23105 HW43_22435 HW43_RS23105 4657867 4659267 - glutamate decarboxylase alpha gene gene4617 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23105 HW43_RS23110 HW43_22440 HW43_RS23110 4659478 4660875 - cytochrome C peroxidase gene gene4618 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23110 HW43_RS23115 HW43_22445 treF treF 4661280 4662929 + trehalase cytoplasmic%3B catalyzes the hydrolysis of trehalose to glucose gene gene4619 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23115 HW43_RS23120 HW43_22450 HW43_RS23120 4662980 4663582 - LuxR family transcriptional regulator gene gene4620 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23120 HW43_RS23125 HW43_22455 HW43_RS23125 4664102 4665001 + LysR family transcriptional regulator gene gene4621 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23125 HW43_RS23130 HW43_22460 HW43_RS23130 4665050 4666063 + membrane protein gene gene4622 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23130 HW43_RS23135 HW43_22465 HW43_RS23135 4666474 4667796 + metabolite transporter gene gene4623 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23135 HW43_RS23140 HW43_22470 HW43_RS23140 4668030 4670090 - hypothetical protein gene gene4624 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23140 HW43_RS23145 HW43_22475 HW43_RS23145 4670160 4670927 - cyclic di-GMP phosphodiesterase YhjH in Escherichia coli this protein is involved in flagellar function gene gene4625 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23145 HW43_RS23150 HW43_25960 HW43_RS23150 4670881 4671075 + hypothetical protein gene gene4626 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23150 HW43_RS23155 HW43_22480 HW43_RS23155 4671159 4672088 + 2-dehydro-3-deoxygluconokinase catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate-6-phosphate from 2-dehydro-3-deoxy-D-gluconate gene gene4627 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23155 HW43_RS23160 HW43_22485 HW43_RS23160 4672184 4673680 - hypothetical protein gene gene4628 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23160 HW43_RS23165 HW43_22490 HW43_RS23165 4673901 4675187 - C4-dicarboxylate ABC transporter involved in the transport of C4-dicarboxylates across the membrane gene gene4629 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23165 HW43_RS23170 HW43_22495 HW43_RS23170 4675370 4677325 - biofilm formation regulator HmsP HmsP in Yersinia pestis plays a role in invasion of epithelial cells%3B the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation%3B inner membrane protein gene gene4630 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23170 HW43_RS23175 HW43_22500 HW43_RS23175 4677440 4680913 - cellulose synthase subunit BcsC cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium%3B the cellulose biosynthesis genes bcsA%2C bcsB%2C bcsZ and bcsC are constitutively transcribed%2C however%2C cellulose synthesis is dependent on the expression of adrA gene gene4631 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23175 HW43_RS23180 HW43_22505 HW43_RS23180 4680895 4682001 - endonuclease III catalyzes the hydrolysis of 1%2C4-beta-D-glucosidic linkages in cellulose%2C lichenin and cereal beta-D-glucans gene gene4632 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23180 HW43_RS23185 HW43_22510 HW43_RS23185 4682008 4684347 - cellulose synthase binds the cellulose synthase activator%2C bis-(3'-5') cyclic diguanylic acid (c-di-GMP) gene gene4633 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23185 HW43_RS23190 HW43_22515 bcsA bcsA 4684358 4686976 - cellulose synthase catalytic subunit [UDP-forming] polymerizes uridine 5'-diphosphate glucose to cellulose%3B acts with BcsB%2C BcsZ and BcsC in cellulose biosynthesis gene gene4634 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23190 HW43_RS23195 HW43_22520 HW43_RS23195 4686973 4687725 - cell division protein gene gene4635 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23195 HW43_RS23200 HW43_22525 HW43_RS23200 4687737 4687925 - hypothetical protein gene gene4636 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23200 HW43_RS23205 HW43_22530 HW43_RS23205 4688210 4689769 + cellulose biosynthesis protein BcsE required for cellulose biosynthesis gene gene4637 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23205 HW43_RS23210 HW43_22535 HW43_RS23210 4689766 4689957 + protein BcsF gene gene4638 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23210 HW43_RS23215 HW43_22540 HW43_RS23215 4689954 4691633 + membrane protein gene gene4639 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23215 HW43_RS23220 HW43_22545 HW43_RS23220 4691720 4691887 - hypothetical protein gene gene4640 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23220 HW43_RS23225 HW43_22550 HW43_RS23225 4692203 4692370 - hypothetical protein gene gene4641 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23225 HW43_RS23230 HW43_22555 HW43_RS23230 4692686 4692853 - hypothetical protein gene gene4642 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23230 HW43_RS23235 HW43_25965 HW43_RS23235 4692958 4693119 - hypothetical protein gene gene4643 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23235 HW43_RS23240 HW43_22560 HW43_RS23240 4693269 4694540 + transporter gene gene4644 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23240 HW43_RS23245 HW43_22565 dppF dppF 4694570 4695574 - peptide ABC transporter ATP-binding protein Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides gene gene4645 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23245 HW43_RS23250 HW43_22570 dppD dppD 4695571 4696554 - dipeptide transport ATP-binding protein DppD DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF gene gene4646 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23250 HW43_RS23255 HW43_22575 HW43_RS23255 4696565 4697467 - peptide ABC transporter permease gene gene4647 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23255 HW43_RS23260 HW43_22580 HW43_RS23260 4697477 4698496 - peptide ABC transporter permease gene gene4648 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23260 HW43_RS23265 HW43_25970 HW43_RS23265 4698514 4698741 + hypothetical protein gene gene4649 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23265 HW43_RS23270 HW43_22585 HW43_RS23270 4698804 4700411 - periplasmic dipeptide transporter DppABCDF is involved in the transport of dipeptides%3B also binds heme and mediates chemotaxis to dipeptides gene gene4650 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23270 HW43_RS23275 HW43_22590 HW43_RS23275 4701324 4701400 - tRNA-Pro tRNA gene4651 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23275 HW43_RS23280 HW43_22595 HW43_RS23280 4701492 4703183 - phosphoethanolamine transferase catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide gene gene4652 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23280 HW43_RS23285 HW43_22600 HW43_RS23285 4703436 4703960 - long polar fimbrial protein LpfE gene gene4653 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23285 HW43_RS23290 HW43_22605 HW43_RS23290 4703966 4705021 - hypothetical protein gene gene4654 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23290 HW43_RS23295 HW43_22610 HW43_RS23295 4705032 4707563 - fimbrial outer membrane usher protein SthC gene gene4655 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23295 HW43_RS23300 HW43_22615 HW43_RS23300 4707587 4708273 - long polar fimbrial chaperone LpfB binds with fimbrial subunit LpfA gene gene4656 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23300 HW43_RS23305 HW43_22620 HW43_RS23305 4708357 4708881 - long polar fimbrial protein LpfA gene gene4657 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23305 HW43_RS23310 HW43_22625 HW43_RS23310 4709206 4710408 - membrane protein gene gene4658 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23310 HW43_RS23315 HW43_22630 HW43_RS23315 4710637 4711335 - hypothetical protein gene gene4659 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23315 HW43_RS23320 HW43_22635 HW43_RS23320 4711493 4712056 + DNA-3-methyladenine glycosylase gene gene4660 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23320 HW43_RS23325 HW43_22640 HW43_RS23325 4712053 4712493 + acetyltransferase gene gene4661 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23325 HW43_RS23330 HW43_22645 HW43_RS23330 4712462 4714741 - biotin sulfoxide reductase catalyzes the reduction of trimethylamine-N-oxide to form trimethylamine gene gene4662 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23330 HW43_RS23335 HW43_22650 HW43_RS23335 4714948 4715607 + lipoprotein gene gene4663 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23335 HW43_RS23340 HW43_22655 HW43_RS23340 4715711 4716685 + glyoxylate/hydroxypyruvate reductase B catalyzes the formation of glycolate from glyoxylate and glycerate from hydroxypyruvate gene gene4664 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23340 HW43_RS23345 HW43_22660 HW43_RS23345 4716735 4717445 - DUF3053 domain-containing protein gene gene4665 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23345 HW43_RS23350 HW43_22665 HW43_RS23350 4717879 4718169 + transcriptional regulator gene gene4666 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23350 HW43_RS23355 HW43_22670 HW43_RS23355 4718450 4718662 + cold-shock protein gene gene4667 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23355 HW43_RS23360 HW43_25975 HW43_RS23360 4718850 4719002 - hypothetical protein gene gene4668 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23360 HW43_RS23365 HW43_22675 glyS glyS 4719328 4721397 - glycine--tRNA ligase subunit beta glycine--tRNA ligase beta chain%3B glyS%3B class II aminoacyl tRNA synthetase%3B tetramer of alpha(2)beta(2)%3B catalyzes a two-step reaction%3B first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP%3B second by transfer of the aminoacyl-adenylate to its tRNA gene gene4669 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23365 HW43_RS23370 HW43_22680 HW43_RS23370 4721407 4722318 - glycine--tRNA ligase subunit alpha gene gene4670 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23370 HW43_RS23375 HW43_22685 HW43_RS23375 4722413 4722712 - hypothetical protein gene gene4671 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23375 HW43_RS23380 HW43_22690 HW43_RS23380 4722887 4723882 + O-acetyltransferase involved in enterobacterial common antigen biosynthesis%3B catalyzes the addition of O-acetyl groups to the N-acetyl-D-glucosamine residues of the trisaccharide repeat units of the enterobacterial common antigen gene gene4672 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23380 HW43_RS23385 HW43_22695 HW43_RS23385 4723924 4724361 - hypothetical protein gene gene4673 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23385 HW43_RS23390 HW43_22700 HW43_RS23390 4724407 4724748 - hypothetical protein gene gene4674 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23390 HW43_RS23395 HW43_22705 HW43_RS23395 4724917 4726371 - xylulokinase catalyzes the formation of D-xylulose-5-phosphate fro D-xylulose gene gene4675 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23395 HW43_RS23400 HW43_22710 HW43_RS23400 4726443 4727765 - xylose isomerase catalyzes the interconversion of D-xylose to D-xylulose gene gene4676 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23400 HW43_RS23405 HW43_22715 xylF xylF 4728131 4729123 + xylose ABC transporter substrate-binding protein periplasmic substrate-binding component of the ATP-dependent xylose transport system%3B high affinity gene gene4677 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23405 HW43_RS23410 HW43_22720 HW43_RS23410 4729201 4730742 + xylose ABC transporter ATP-binding protein with XylFH is part of the high affinity xylose ABC transporter gene gene4678 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23410 HW43_RS23415 HW43_22725 HW43_RS23415 4730720 4731901 + xylose ABC transporter permease gene gene4679 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23415 HW43_RS23420 HW43_22730 HW43_RS23420 4731979 4733157 + xylose operon regulatory protein gene gene4680 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23420 HW43_RS23425 HW43_25980 HW43_RS23425 4733265 4734089 - protein bax gene gene4681 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23425 HW43_RS23430 HW43_22740 malS malS 4734409 4736439 + alpha-amylase periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB%3B hydrolyzes alpha-(1%2C4) glycosidic linkages%3B contains internal disulfide bonds gene gene4682 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23430 HW43_RS23435 HW43_22745 avtA avtA 4736617 4737870 + valine--pyruvate aminotransferase transaminase C%3B catalyzes transamination of alanine%2C valine%2C and 2-aminobutyrate with their respective 2-keto acids%3B also catalyzes terminal step in valine biosynthesis gene gene4683 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23435 HW43_RS23440 HW43_25985 HW43_RS23440 4737874 4738002 + hypothetical protein gene gene4684 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23440 HW43_RS23445 HW43_22750 HW43_RS23445 4738021 4738494 - electron transporter gene gene4685 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23445 HW43_RS23450 HW43_22755 HW43_RS23450 4738596 4739444 - transcriptional regulator gene gene4686 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23450 HW43_RS23455 HW43_22760 HW43_RS23455 4739645 4740643 + 2%2C3-diketo-L-gulonate reductase NAD(P)H-dependent%3B catalyzes the reduction of 2%2C3-diketo-L-gulonate to 3-keto-L-gulonate gene gene4687 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23455 HW43_RS23460 HW43_22765 HW43_RS23460 4740655 4741122 + hypothetical protein gene gene4688 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23460 HW43_RS23465 HW43_22770 HW43_RS23465 4741240 4741713 + 2%2C3-diketo-L-gulonate TRAP transporter permease membrane-spanning protein involved in uptake of 2%2C3-diketo-L-gulonate%3B part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO gene gene4689 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23465 HW43_RS23470 HW43_22775 HW43_RS23470 4741716 4742993 + 2%2C3-diketo-L-gulonate TRAP transporter permease TRAP family transporter%3B with YiaMO is involved in the uptake of L-dehydroascorbate gene gene4690 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23470 HW43_RS23475 HW43_22780 HW43_RS23475 4743006 4743992 + transporter involved in the transport of 2%2C3-diketo-L-gulonate gene gene4691 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23475 HW43_RS23480 HW43_22785 HW43_RS23480 4743996 4745492 + L-xylulose/3-keto-L-gulonate kinase catalyzes the formation of L-xylulose 5-phosphate and 3-dehydro-L-gulonate 6-phosphate from L-xylulose or 3-dehydro-L-gulonate%2C respectively gene gene4692 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23480 HW43_RS23485 HW43_22790 sgbH sgbH 4745489 4746151 + 3-keto-L-gulonate-6-phosphate decarboxylase catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate gene gene4693 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23485 HW43_RS23490 HW43_22795 HW43_RS23490 4746144 4747004 + L-xylulose 5-phosphate 3-epimerase L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated%3B may be involved in the utilization of 2%2C3-diketo-L-gulonate gene gene4694 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23490 HW43_RS23495 HW43_22800 araD araD 4746998 4747693 + L-ribulose-5-phosphate 4-epimerase catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate%3B links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source gene gene4695 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23495 HW43_RS23500 HW43_22810 HW43_RS23500 4748040 4748780 - membrane protein gene gene4696 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23500 HW43_RS23505 HW43_22815 HW43_RS23505 4748904 4749878 + LysR family transcriptional regulator gene gene4697 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23505 HW43_RS23510 HW43_22820 HW43_RS23510 4749875 4751011 - hypothetical protein gene gene4698 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23510 HW43_RS23515 HW43_22825 HW43_RS23515 4751017 4751340 - hypothetical protein gene gene4699 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23515 HW43_RS23520 HW43_25990 HW43_RS23520 4751454 4751666 + membrane protein gene gene4700 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23520 HW43_RS23525 HW43_22835 HW43_RS23525 4751885 4753423 - aldehyde dehydrogenase catalyzes the oxidation of acetaldehyde%2C benzaldehyde%2C propionaldehyde and other aldehydes gene gene4701 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23525 HW43_RS23530 HW43_22840 HW43_RS23530 4753588 4754739 - alcohol dehydrogenase gene gene4702 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23530 HW43_RS23535 HW43_22845 HW43_RS23535 4754929 4756773 - selenocysteine-specific translation elongation factor gene gene4703 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23535 HW43_RS23540 HW43_22850 HW43_RS23540 4756770 4758161 - L-seryl-tRNA(Sec) selenium transferase catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis gene gene4704 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23540 HW43_RS23545 HW43_22855 HW43_RS23545 4758259 4758867 - glutathione S-transferase gene gene4705 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23545 HW43_RS23550 HW43_22860 HW43_RS23550 4759096 4763331 + RHS element protein RhsA gene gene4706 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23550 HW43_RS23555 HW43_22865 HW43_RS23555 4763303 4763686 + hypothetical protein gene gene4707 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23555 HW43_RS23560 HW43_22870 HW43_RS23560 4763791 4764633 + lyase gene gene4708 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23560 HW43_RS23565 HW43_22875 HW43_RS23565 4764681 4765619 + type IV secretion protein Rhs gene gene4709 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23565 HW43_RS23570 HW43_22880 HW43_RS23570 4765631 4766092 + hypothetical protein gene gene4710 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23570 HW43_RS23575 HW43_22885 HW43_RS23575 4766799 4767236 + hypothetical protein gene gene4711 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23575 HW43_RS23580 HW43_22890 HW43_RS23580 4767695 4768831 - hypothetical protein gene gene4712 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23580 HW43_RS23585 HW43_22895 HW43_RS23585 4768834 4769196 - hypothetical protein gene gene4713 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23585 HW43_RS23590 HW43_22900 HW43_RS23590 4769733 4771646 + PTS mannitol EIICBA component catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B subunit IIC forms the translocation channel and contains the specific substrate-binding site%3B subunit IIA is phosphorylated and transfers the phosphoryl group to the IIB subunit%3B subunit IIB transfers the phosphoryl group to the substrate gene gene4714 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23590 HW43_RS23595 HW43_22905 HW43_RS23595 4771876 4773024 + mannitol-1-phosphate 5-dehydrogenase gene gene4715 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23595 HW43_RS23600 HW43_22910 HW43_RS23600 4773021 4773611 + hypothetical protein gene gene4716 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23600 HW43_RS23605 HW43_22915 HW43_RS23605 4773623 4773832 - hypothetical protein gene gene4717 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23605 HW43_RS23610 HW43_22920 HW43_RS23610 4774117 4774479 + ribosome-associated protein gene gene4718 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23610 HW43_RS23615 HW43_22925 HW43_RS23615 4775023 4775706 + membrane protein gene gene4719 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23615 HW43_RS23620 HW43_22930 HW43_RS23620 4775750 4780600 + adhesin gene gene4720 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23620 HW43_RS23625 HW43_22935 HW43_RS23625 4780969 4782624 + L-lactate permease gene gene4721 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23625 HW43_RS23630 HW43_22940 HW43_RS23630 4782624 4783400 + transcriptional regulator represses the lctPRD operon gene gene4722 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23630 HW43_RS23635 HW43_22945 lldD lldD 4783397 4784587 + lactate dehydrogenase flavin mononucleotide-dependent dehydrogenase%3B functions in aerobic respiration and also has a role in anaerobic nitrate respiration gene gene4723 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23635 HW43_RS23640 HW43_22950 HW43_RS23640 4784773 4785246 + rRNA methyltransferase member of the SPOUT superfamily of RNA methyltransferases gene gene4724 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23640 HW43_RS23645 HW43_22955 cysE cysE 4785299 4786120 - serine acetyltransferase catalyzes the O-acetylation of serine gene gene4725 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23645 HW43_RS23650 HW43_22960 HW43_RS23650 4786200 4787219 - glycerol-3-phosphate dehydrogenase [NAD(P)+] gene gene4726 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23650 HW43_RS23655 HW43_22965 HW43_RS23655 4787219 4787686 - protein-export protein SecB molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm%3B in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA gene gene4727 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23655 HW43_RS23660 HW43_22970 HW43_RS23660 4787749 4788000 - glutaredoxin gene gene4728 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23660 HW43_RS23665 HW43_22975 HW43_RS23665 4788142 4788573 - hypothetical protein gene gene4729 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23665 HW43_RS23670 HW43_22980 HW43_RS23670 4788818 4790362 + phosphoglyceromutase catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gene gene4730 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23670 HW43_RS23675 HW43_22985 HW43_RS23675 4790372 4791655 + peptidase M37 gene gene4731 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23675 HW43_RS23680 HW43_22990 HW43_RS23680 4791659 4792618 + hypothetical protein gene gene4732 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23680 HW43_RS23685 HW43_22995 HW43_RS23685 4792605 4793639 - glycosyl transferase gene gene4733 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23685 HW43_RS23690 HW43_23000 tdh tdh 4793878 4794903 - L-threonine 3-dehydrogenase converts threonine and NAD to 1%2C2-amino-3-oxobutanoate and NADH%3B functions in threonine catabolism gene gene4734 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23690 HW43_RS23695 HW43_23005 HW43_RS23695 4794913 4796109 - 2-amino-3-ketobutyrate CoA ligase catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine gene gene4735 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23695 HW43_RS23700 HW43_23010 HW43_RS23700 4796384 4797241 - hypothetical protein gene gene4736 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23700 HW43_RS23705 HW43_23015 rfaD rfaD 4797545 4798477 + ADP-L-glycero-D-manno-heptose-6-epimerase catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose gene gene4737 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23705 HW43_RS23710 HW43_23020 HW43_RS23710 4798487 4799533 + ADP-heptose--LPS heptosyl transferase catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core gene gene4738 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23710 HW43_RS23715 HW43_23025 HW43_RS23715 4799537 4800529 + ADP-heptose--LPS heptosyl transferase gene gene4739 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23715 HW43_RS23720 HW43_23030 HW43_RS23720 4800526 4801734 + ligase gene gene4740 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23720 HW43_RS23725 HW43_23035 HW43_RS23725 4801770 4802912 - LPS 1%2C2-N-acetylglucosaminetransferase gene gene4741 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23725 HW43_RS23730 HW43_23040 HW43_RS23730 4802921 4803934 - UDP-glucose--(galactosyl) LPS alpha1%2C2-glucosyltransferase gene gene4742 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23730 HW43_RS23735 HW43_23045 HW43_RS23735 4803959 4804666 - LPS biosynthesis protein gene gene4743 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23735 HW43_RS23740 HW43_23050 HW43_RS23740 4804692 4805699 - LPS 1%2C3-galactosyltransferase gene gene4744 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23740 HW43_RS23745 HW43_23055 HW43_RS23745 4805742 4806539 - LPS core heptose(I) kinase RfaP catalyzes the phosphorylation of heptose I in the lipopolysaccharide core gene gene4745 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23745 HW43_RS23750 HW43_23060 HW43_RS23750 4806532 4807656 - glucosyltransferase catalyzes the addition of the first glucose residue to the LPS core gene gene4746 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23750 HW43_RS23755 HW43_23065 HW43_RS23755 4807653 4808675 - LPS core heptosyltransferase RfaQ catalyzes the transfer of heptose(III) to heptose(II) in the lipopolysaccharide inner core gene gene4747 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23755 HW43_RS23760 HW43_23070 HW43_RS23760 4809124 4810401 + 3-deoxy-D-manno-octulosonic acid transferase catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A gene gene4748 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23760 HW43_RS23765 HW43_23075 coaD coaD 4810409 4810888 + phosphopantetheine adenylyltransferase Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA gene gene4749 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23765 HW43_RS23770 HW43_23080 HW43_RS23770 4810927 4811736 - formamidopyrimidine-DNA glycosylase Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases gene gene4750 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23770 HW43_RS23775 HW43_23085 rpmG rpmG 4811834 4812001 - 50S ribosomal protein L33 in Escherichia coli BM108%2C a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function%3B there are paralogous genes in several bacterial genomes%2C and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31%3B the proteins in this group lack the CXXC motif gene gene4751 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23775 HW43_RS23780 HW43_23090 rpmB rpmB 4812022 4812258 - 50S ribosomal protein L28 required for 70S ribosome assembly gene gene4752 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23780 HW43_RS23785 HW43_23095 HW43_RS23785 4812475 4813143 - hypothetical protein gene gene4753 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23785 HW43_RS23790 HW43_23100 HW43_RS23790 4813315 4814535 + phosphopantothenoylcysteine decarboxylase catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine%2C which is then decarboxylated to form 4'-phosphopantotheine gene gene4754 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23790 HW43_RS23795 HW43_23105 HW43_RS23795 4814513 4814971 + deoxyuridine 5'-triphosphate nucleotidohydrolase catalyzes the formation of dUMP from dUTP gene gene4755 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23795 HW43_RS23800 HW43_23110 slmA slmA 4815078 4815674 + nucleoid occlusion factor SlmA FtsZ binding protein%3B synthetically lethal with a defect in the Min system%3B this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly gene gene4756 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23800 HW43_RS23805 HW43_23115 pyrE pyrE 4815711 4816352 - orotate phosphoribosyltransferase involved in fifth step of pyrimidine biosynthesis%3B converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate gene gene4757 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23805 HW43_RS23810 HW43_23120 rph rph 4816418 4817134 - ribonuclease PH RNase PH%3B tRNA nucleotidyltransferase%3B forms hexamers in Bacillus subtilis%3B phosphoroltic 3'-5' exoribonuclease%3B involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs gene gene4758 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23810 HW43_RS23815 HW43_23125 HW43_RS23815 4817261 4818124 + hypothetical protein gene gene4759 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23815 HW43_RS23820 HW43_23130 dinD dinD 4818345 4819169 + DNA damage-inducible protein D gene gene4760 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23820 HW43_RS23825 HW43_23135 HW43_RS23825 4819461 4820078 + hypothetical protein gene gene4761 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23825 HW43_RS23830 HW43_23140 ligB ligB 4820075 4821757 - DNA ligase B this ligase is similar to LigA but it lacks the C-terminal BRCT domain%3B catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ gene gene4762 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23830 HW43_RS23835 HW43_23145 gmk gmk 4822015 4822638 + guanylate kinase Essential for recycling GMP and indirectly%2C cGMP gene gene4763 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23835 HW43_RS23840 HW43_23150 rpoZ rpoZ 4822693 4822968 + DNA-directed RNA polymerase subunit omega Promotes RNA polymerase assembly%3B latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits gene gene4764 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23840 HW43_RS23845 HW43_23155 HW43_RS23845 4822987 4825095 + bifunctional (p)ppGpp synthetase II/ guanosine-3'%2C5'-bis pyrophosphate 3'-pyrophosphohydrolase gene gene4765 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23845 HW43_RS23850 HW43_23160 HW43_RS23850 4825102 4825791 + tRNA (guanosine(18)-2'-O)-methyltransferase specifically modifies tRNA at position G18 gene gene4766 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23850 HW43_RS23855 HW43_23165 HW43_RS23855 4825797 4827878 + ATP-dependent DNA helicase RecG catalyzes branch migration in Holliday junction intermediates gene gene4767 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23855 HW43_RS23860 HW43_23170 HW43_RS23860 4828044 4829249 - sodium/glutamate symport carrier protein is involved with the sodium-dependent uptake of glutamate gene gene4768 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23860 HW43_RS23865 HW43_23175 HW43_RS23865 4829529 4830920 + xanthine permease XanP high-affinity transporter for xanthine gene gene4769 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23865 HW43_RS23870 HW43_23180 HW43_RS23870 4831041 4832750 + hypothetical protein gene gene4770 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23870 HW43_RS23875 HW43_23185 HW43_RS23875 4832803 4835121 - alpha-glucosidase catalyzes the transfer of alpha-xylosyl residue gene gene4771 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23875 HW43_RS23880 HW43_23190 HW43_RS23880 4835131 4836513 - inner membrane symporter YicJ may be involved in the transport of galactosides-pentoses-hexuronides gene gene4772 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23880 HW43_RS23885 HW43_23195 HW43_RS23885 4836806 4836900 + tRNA-Sec tRNA gene4773 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23885 HW43_RS23890 HW43_25995 HW43_RS23890 4837009 4837155 + hypothetical protein gene gene4774 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23890 HW43_RS23895 HW43_23200 HW43_RS23895 4837537 4838721 + sugar transporter gene gene4775 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23895 HW43_RS23900 HW43_23205 HW43_RS23900 4838832 4839755 + membrane protein gene gene4776 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23900 HW43_RS23905 HW43_23210 HW43_RS23905 4839759 4840577 - methionine ABC transporter substrate-binding protein gene gene4777 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23905 HW43_RS23910 HW43_26000 HW43_RS23910 4840675 4840794 + hypothetical protein gene gene4778 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23910 HW43_RS23915 HW43_23220 HW43_RS23915 4840799 4841092 + hypothetical protein gene gene4779 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23915 HW43_RS23920 HW43_23225 nepI nepI 4841133 4842323 - purine ribonucleoside efflux pump NepI experimental results in Escherichia coli suggest that this gene encodes an inosine export protein%3B member of major facilitator superfamily%3B MFS gene gene4780 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23920 HW43_RS23925 HW43_23230 HW43_RS23925 4842534 4842986 - DUF1198 domain-containing protein gene gene4781 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23925 HW43_RS23930 HW43_23235 HW43_RS23930 4843039 4844451 - adenine permease involved in the transport or adenine gene gene4782 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23930 HW43_RS23935 HW43_23240 HW43_RS23935 4844548 4846314 + adenine deaminase catalyzes the formation of hypoxanthine from adenine%3B in E. coli this activity has been detected in mutant strains but not in wild type gene gene4783 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23935 HW43_RS23940 HW43_23245 uhpT uhpT 4846359 4847750 - hexose phosphate transporter cytoplasmic membrane protein that functions as a monomer%3B catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate gene gene4784 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23940 HW43_RS23945 HW43_23250 HW43_RS23945 4847888 4849207 - hypothetical protein membrane protein regulates uhpT expression gene gene4785 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23945 HW43_RS23950 HW43_23255 HW43_RS23950 4849217 4850719 - sensor histidine kinase Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph gene gene4786 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23950 HW43_RS23955 HW43_23260 HW43_RS23955 4850719 4851309 - transcriptional regulator response regulator in two-component regulatory system wtih UhpB%3B phosphorylated UhpA is a positive activator uhpT%2C a hexose phosphates transporter gene gene4787 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23955 HW43_RS23960 HW43_23265 HW43_RS23960 4851384 4851674 - acetolactate synthase isozyme 1 small subunit with IlvB catalyzes the formation of 2-acetolactate from pyruvate%2C the small subunit is required for full activity and valine sensitivity%3B E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates%2C valine sensitivity and affinity for cofactors%3B also known as acetolactate synthase small subunit gene gene4788 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23960 HW43_RS23965 HW43_23270 HW43_RS23965 4851678 4853366 - acetolactate synthase gene gene4789 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23965 HW43_RS23970 HW43_26010 HW43_RS23970 4853455 4853847 + hypothetical protein gene gene4790 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23970 HW43_RS23975 HW43_26015 HW43_RS23975 4853844 4854002 + hypothetical protein gene gene4791 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23975 HW43_RS23980 HW43_26020 HW43_RS23980 4854135 4854224 + toxic peptide TisB gene gene4792 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23980 HW43_RS23985 HW43_23285 emrD emrD 4854643 4855827 + multidrug resistance protein D multidrug efflux protein involved in adaptation to low energy shock gene gene4793 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23985 HW43_RS23990 HW43_23290 HW43_RS23990 4855835 4856332 - transcriptional regulator gene gene4794 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23990 HW43_RS23995 HW43_23295 HW43_RS23995 4856329 4856691 - membrane protein gene gene4795 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS23995 HW43_RS24000 HW43_23300 HW43_RS24000 4856681 4857028 - hypothetical protein gene gene4796 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24000 HW43_RS24005 HW43_23305 HW43_RS24005 4857137 4857586 + membrane protein gene gene4797 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24005 HW43_RS24010 HW43_23310 HW43_RS24010 4857633 4859126 - hypothetical protein gene gene4798 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24010 HW43_RS24015 HW43_23315 HW43_RS24015 4859123 4860838 - AraC family transcriptional regulator uncharacterized member of the SSS superfamily of sodium-dependent solute transporters%3B unknown function gene gene4799 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24015 HW43_RS24020 HW43_23320 HW43_RS24020 4861005 4861898 + AraC family transcriptional regulator gene gene4800 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24020 HW43_RS24025 HW43_23330 HW43_RS24025 4862071 4862709 - inactive 6-phospho-alpha-glucosidase gene gene4801 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24025 HW43_RS24030 HW43_23335 HW43_RS24030 4862709 4864325 - PTS alpha-glucoside transporter subunit IIBC involved in the phosphorylation and transport of sugars across the cell membrane%3B protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel for the sugar uptake gene gene4802 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24030 HW43_RS24035 HW43_26025 HW43_RS24035 4864621 4864776 + GntR family transcriptional regulator gene gene4803 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24035 HW43_RS24040 HW43_26030 HW43_RS24040 4864780 4865337 + GntR family transcriptional regulator gene gene4804 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24040 HW43_RS24045 HW43_23345 HW43_RS24045 4865334 4866995 - transporter gene gene4805 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24045 HW43_RS24050 HW43_23350 HW43_RS24050 4867192 4867620 - heat-shock protein IbpB 16 kDa heat shock protein B%3B associates with aggregated proteins%2C together with ibpA%2C to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress%3B ATP-independent gene gene4806 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24050 HW43_RS24055 HW43_23355 HW43_RS24055 4867732 4868145 - heat-shock protein IbpA with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress gene gene4807 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24055 HW43_RS24060 HW43_23360 HW43_RS24060 4868523 4868783 + hypothetical protein gene gene4808 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24060 HW43_RS24065 HW43_23365 HW43_RS24065 4868785 4869999 - hypothetical protein gene gene4809 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24065 HW43_RS24070 HW43_23370 HW43_RS24070 4870100 4871164 + oxidoreductase FAD/NAD(P)-binding domain gene gene4810 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24070 HW43_RS24075 HW43_23375 HW43_RS24075 4871161 4872453 - D-galactonate transporter gene gene4811 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24075 HW43_RS24080 HW43_23380 HW43_RS24080 4872573 4873721 - D-galactonate dehydratase 2 gene gene4812 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24080 HW43_RS24085 HW43_23385 HW43_RS24085 4873718 4874335 - 2-dehydro-3-deoxy-6-phosphogalactonate aldolase catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate%3B functions in galactonate metabolism gene gene4813 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24085 HW43_RS24090 HW43_23390 HW43_RS24090 4874319 4875197 - 2-oxo-3-deoxygalactonate kinase catalyzes the formation of 2-dehydro-3-deoxy-D-galactonate 6-phosphate from 2-dehydro-3-deoxy-D-galactonate gene gene4814 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24090 HW43_RS24095 HW43_23395 HW43_RS24095 4875194 4875883 - transcriptional regulator gene gene4815 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24095 HW43_RS24100 HW43_23400 HW43_RS24100 4876161 4876817 + hypothetical protein gene gene4816 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24100 HW43_RS24105 HW43_23405 HW43_RS24105 4876863 4877675 - sugar phosphate phosphatase YidA%3B catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate)%2C mannose 1-phosphate and p-nitrophenyl phosphate%3B hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form%3B member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins gene gene4817 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24105 HW43_RS24110 HW43_23410 HW43_RS24110 4877790 4878188 - DUF937 domain-containing protein gene gene4818 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24110 HW43_RS24115 HW43_26035 HW43_RS24115 4878208 4878408 - hypothetical protein gene gene4819 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24115 HW43_RS24120 HW43_23415 gyrB gyrB 4878428 4880842 - DNA gyrase subunit B negatively supercoils closed circular double-stranded DNA gene gene4820 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24120 HW43_RS24125 HW43_23420 recF recF 4880871 4881944 - DNA recombination protein RecF Required for DNA replication%3B binds preferentially to single-stranded%2C linear DNA gene gene4821 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24125 HW43_RS24130 HW43_23425 HW43_RS24130 4881944 4883044 - DNA polymerase III subunit beta binds the polymerase to DNA and acts as a sliding clamp gene gene4822 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24130 HW43_RS24135 HW43_23430 dnaA dnaA 4883049 4884452 - chromosomal replication initiator protein DnaA binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication%3B can also affect transcription of multiple genes including itself. gene gene4823 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24135 HW43_RS24140 HW43_23490 HW43_RS24140 1 572 + pilus assembly protein gene gene4824 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24140 HW43_RS24145 HW43_23495 HW43_RS24145 624 1019 + pilus assembly protein PilP gene gene4825 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24145 HW43_RS24150 HW43_23500 HW43_RS24150 1104 2611 + type II secretion protein E gene gene4826 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24150 HW43_RS24155 HW43_23505 HW43_RS24155 2613 3713 + type II secretion protein F gene gene4827 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24155 HW43_RS24160 HW43_23510 HW43_RS24160 3787 4323 + cleavage protein gene gene4828 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24160 HW43_RS24165 HW43_23515 HW43_RS24165 4377 4850 + lytic transglycosylase gene gene4829 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24165 HW43_RS24170 HW43_23520 HW43_RS24170 4869 5501 + peptidase A24 gene gene4830 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24170 HW43_RS24175 HW43_23525 HW43_RS24175 5506 6870 + hypothetical protein gene gene4831 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24175 HW43_RS24180 HW43_23540 HW43_RS24180 7328 7618 + hypothetical protein gene gene4832 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24180 HW43_RS24185 HW43_23545 HW43_RS24185 7710 8030 - hypothetical protein gene gene4833 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24185 HW43_RS24190 HW43_23550 HW43_RS24190 8290 9111 + conjugal transfer protein TraE gene gene4834 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24190 HW43_RS24195 HW43_23555 HW43_RS24195 9201 10403 + conjugal transfer protein TraF gene gene4835 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24195 HW43_RS24200 HW43_23565 HW43_RS24200 10762 11214 + hypothetical protein gene gene4836 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24200 HW43_RS24205 HW43_23570 HW43_RS24205 11211 12047 + conjugal transfer protein gene gene4837 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24205 HW43_RS24210 HW43_23575 HW43_RS24210 12031 13179 + conjugal transfer protein gene gene4838 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24210 HW43_RS24215 HW43_23580 HW43_RS24215 13176 13466 + conjugal transfer protein gene gene4839 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24215 HW43_RS24220 HW43_23585 HW43_RS24220 13530 17552 + DNA primase gene gene4840 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24220 HW43_RS24225 HW43_23590 HW43_RS24225 17569 17919 + conjugal transfer protein gene gene4841 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24225 HW43_RS24230 HW43_23595 HW43_RS24230 17931 18626 + conjugal transfer protein TraM gene gene4842 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24230 HW43_RS24235 HW43_23600 HW43_RS24235 18637 19611 + conjugal transfer protein TraN gene gene4843 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24235 HW43_RS24240 HW43_23605 HW43_RS24240 19615 20946 + conjugal transfer protein TraO gene gene4844 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24240 HW43_RS24245 HW43_23610 HW43_RS24245 20943 21656 + conjugal transfer protein gene gene4845 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24245 HW43_RS24250 HW43_23615 HW43_RS24250 21656 22183 + conjugal transfer protein TraQ gene gene4846 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24250 HW43_RS24255 HW43_23620 HW43_RS24255 22230 22628 + conjugal transfer protein TraR gene gene4847 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24255 HW43_RS24260 HW43_23625 HW43_RS24260 22685 22936 + traS gene gene4848 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24260 HW43_RS24265 HW43_23630 HW43_RS24265 23043 23669 + conjugal transfer protein TraT gene gene4849 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24265 HW43_RS24270 HW43_23635 HW43_RS24270 23724 24083 + hypothetical protein gene gene4850 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24270 HW43_RS24275 HW43_23640 HW43_RS24275 24083 24463 + hypothetical protein gene gene4851 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24275 HW43_RS24280 HW43_23645 HW43_RS24280 24639 27683 + conjugal transfer protein gene gene4852 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24280 HW43_RS24285 HW43_23650 HW43_RS24285 27683 28300 + hypothetical protein gene gene4853 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24285 HW43_RS24290 HW43_23655 HW43_RS24290 28261 29466 + conjugal transfer protein gene gene4854 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24290 HW43_RS24295 HW43_23660 HW43_RS24295 29567 30031 + conjugal transfer protein TraX gene gene4855 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24295 HW43_RS24300 HW43_23665 HW43_RS24300 30104 32263 + membrane protein gene gene4856 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24300 HW43_RS24305 HW43_23670 HW43_RS24305 32345 32992 + hypothetical protein gene gene4857 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24305 HW43_RS24310 HW43_23675 HW43_RS24310 33148 33309 + antitoxin gene gene4858 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24310 HW43_RS24315 HW43_RS24315 HW43_RS24315 33306 33458 - protein pndA gene gene4859 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24315 HW43_RS24320 HW43_23680 HW43_RS24320 33792 34034 + hypothetical protein gene gene4860 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24320 HW43_RS24325 HW43_23685 HW43_RS24325 34127 35671 - phosphoethanolamine transferase yhbX gene gene4861 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24325 HW43_RS24330 HW43_23690 HW43_RS24330 35862 36317 - hypothetical protein gene gene4862 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24330 HW43_RS24335 HW43_23695 HW43_RS24335 36405 37028 - DNA-binding protein gene gene4863 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24335 HW43_RS24340 HW43_23700 HW43_RS24340 37177 37680 + thermonuclease gene gene4864 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24340 HW43_RS24345 HW43_23705 HW43_RS24345 38043 42122 + autotransporter gene gene4865 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24345 HW43_RS24350 HW43_23710 HW43_RS24350 42425 42616 + hypothetical protein gene gene4866 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24350 HW43_RS24355 HW43_23715 HW43_RS24355 42627 42992 + hypothetical protein gene gene4867 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24355 HW43_RS24360 HW43_23720 HW43_RS24360 43002 43193 + hypothetical protein gene gene4868 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24360 HW43_RS24365 HW43_23725 HW43_RS24365 43224 43535 + flagellar biosynthesis protein FlgM gene gene4869 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24365 HW43_RS24375 HW43_23740 HW43_RS24375 44310 45635 + conjugal transfer protein TrbA gene gene4870 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24375 HW43_RS24380 HW43_23745 HW43_RS24380 45632 46750 + hypothetical protein gene gene4871 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24380 HW43_RS24385 HW43_23750 HW43_RS24385 46731 49034 + conjugal transfer protein TrbC gene gene4872 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24385 HW43_RS24390 HW43_23755 HW43_RS24390 49160 49462 + hypothetical protein gene gene4873 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24390 HW43_RS24395 HW43_23760 HW43_RS24395 49560 49955 - hypothetical protein gene gene4874 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24395 HW43_RS24400 HW43_23765 HW43_RS24400 50059 52770 - relaxase gene gene4875 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24400 HW43_RS24405 HW43_23770 HW43_RS24405 52782 53114 - hypothetical protein gene gene4876 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24405 HW43_RS24410 HW43_23775 HW43_RS24410 53347 53682 + molybdopterin-guanine dinucleotide biosynthesis protein MobC gene gene4877 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24410 HW43_RS24415 HW43_23780 HW43_RS24415 53768 54616 - hypothetical protein gene gene4878 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24415 HW43_RS24420 HW43_RS24420 HW43_RS24420 55033 55353 - hypothetical protein gene gene4879 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24420 HW43_RS24425 HW43_23790 HW43_RS24425 55350 55541 - hypothetical protein gene gene4880 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24425 HW43_RS24430 HW43_23795 HW43_RS24430 55541 55960 - hypothetical protein gene gene4881 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24430 HW43_RS24435 HW43_23800 HW43_RS24435 56007 56432 - antirestriction protein YubI gene gene4882 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24435 HW43_RS24440 HW43_RS24440 HW43_RS24440 56558 56767 + hypothetical protein gene gene4883 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24440 HW43_RS24445 HW43_23810 HW43_RS24445 56847 57623 - hypothetical protein gene gene4884 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24445 HW43_RS24450 HW43_23815 HW43_RS24450 57674 58108 - hypothetical protein gene gene4885 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24450 HW43_RS24455 HW43_23820 HW43_RS24455 58122 58343 - hypothetical protein gene gene4886 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24455 HW43_RS24460 HW43_23825 HW43_RS24460 58344 59027 - methylase gene gene4887 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24460 HW43_RS24465 HW43_23830 HW43_RS24465 59308 60327 - transposase gene gene4888 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24465 HW43_RS24470 HW43_RS24470 HW43_RS24470 60543 60848 - hypothetical protein gene gene4889 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24470 HW43_RS24475 HW43_23835 HW43_RS24475 60852 61778 - hypothetical protein gene gene4890 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24475 HW43_RS24480 HW43_23840 HW43_RS24480 62030 62278 + protein ImpC gene gene4891 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24480 HW43_RS24485 HW43_23845 HW43_RS24485 62275 62712 + DNA polymerase V subunit UmuD gene gene4892 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24485 HW43_RS24490 HW43_23850 HW43_RS24490 62712 63982 + protein ImpB gene gene4893 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24490 HW43_RS24495 HW43_23855 HW43_RS24495 64162 64788 + chromosome partitioning protein ParA gene gene4894 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24495 HW43_RS24500 HW43_23860 HW43_RS24500 64785 65087 + hypothetical protein gene gene4895 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24500 HW43_RS24505 HW43_RS24505 HW43_RS24505 65248 65424 - hypothetical protein gene gene4896 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24505 HW43_RS24510 HW43_23865 HW43_RS24510 65476 65727 + hypothetical protein gene gene4897 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24510 HW43_RS24515 HW43_23870 HW43_RS24515 65727 66317 + hypothetical protein gene gene4898 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24515 HW43_RS24520 HW43_23875 HW43_RS24520 66337 66684 - hypothetical protein gene gene4899 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24520 HW43_RS24525 HW43_23880 HW43_RS24525 66803 67150 + colicin transporter gene gene4900 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24525 HW43_RS24530 HW43_23885 HW43_RS24530 67168 69048 - colicin gene gene4901 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24530 HW43_RS24535 HW43_RS24535 HW43_RS24535 69327 69719 - hypothetical protein gene gene4902 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24535 HW43_RS24540 HW43_RS24540 HW43_RS24540 70015 70224 - transposase gene gene4903 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24540 HW43_RS24545 HW43_23900 HW43_RS24545 70290 70496 + hypothetical protein gene gene4904 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24545 HW43_RS24550 HW43_23905 HW43_RS24550 70721 72694 + ligand-gated channel gene gene4905 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24550 HW43_RS24555 HW43_23910 HW43_RS24555 72713 73504 + ABC transporter gene gene4906 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24555 HW43_RS24560 HW43_23915 HW43_RS24560 74009 74434 + transposase gene gene4907 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24560 HW43_RS24565 HW43_23920 HW43_RS24565 74431 74781 + isocitrate lyase gene gene4908 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24565 HW43_RS24570 HW43_23925 HW43_RS24570 74878 76404 + transposase gene gene4909 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24570 HW43_RS24575 HW43_23935 HW43_RS24575 76609 77025 - recombinase gene gene4910 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24575 HW43_RS24580 HW43_23940 HW43_RS24580 77018 77998 - Plasmid segregation protein parM gene gene4911 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24580 HW43_RS24585 HW43_23945 HW43_RS24585 78413 78721 - molecular chaperone GroeL gene gene4912 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24585 HW43_RS24590 HW43_23950 HW43_RS24590 78808 79452 - chromosome partitioning protein ParA gene gene4913 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24590 HW43_RS24595 HW43_23955 HW43_RS24595 79633 80439 - resolvase gene gene4914 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24595 HW43_RS24600 HW43_23960 HW43_RS24600 80440 80745 - hypothetical protein controlled cell death protein%3B post-segregation toxin%3B toxin addiction system gene gene4915 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24600 HW43_RS24605 HW43_23965 HW43_RS24605 80747 80965 - antitoxin CcdA gene gene4916 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24605 HW43_RS24610 HW43_23970 HW43_RS24610 81149 81364 + hypothetical protein gene gene4917 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24610 HW43_RS24615 HW43_23975 HW43_RS24615 81561 81821 + hypothetical protein gene gene4918 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24615 HW43_RS24620 HW43_23980 HW43_RS24620 81818 82408 + hypothetical protein gene gene4919 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24620 HW43_RS24625 HW43_23985 HW43_RS24625 82426 82773 - hypothetical protein gene gene4920 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24625 HW43_RS24630 HW43_23990 HW43_RS24630 82902 83237 + colicin transporter gene gene4921 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24630 HW43_RS24635 HW43_23995 HW43_RS24635 83244 83564 - colicin gene gene4922 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24635 HW43_RS24640 HW43_24000 HW43_RS24640 83674 84405 - conjugal transfer protein TraT gene gene4923 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24640 HW43_RS24645 HW43_RS24645 HW43_RS24645 85413 85583 + hypothetical protein gene gene4924 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24645 HW43_RS24650 HW43_24005 HW43_RS24650 85576 86553 + protein RepA gene gene4925 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24650 HW43_RS24655 HW43_RS24655 HW43_RS24655 86813 87063 - transposase gene gene4926 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24655 HW43_RS24665 HW43_24010 HW43_RS24665 87500 88405 - transposase gene gene4928 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24665 HW43_RS24670 HW43_24015 HW43_RS24670 88363 88728 - transposase represses IS2 gene transcription gene gene4929 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24670 HW43_RS24675 HW43_24020 HW43_RS24675 88904 89398 - transcriptional regulator gene gene4930 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24675 HW43_RS24680 HW43_24025 HW43_RS24680 89519 90958 - hypothetical protein gene gene4931 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24680 HW43_RS24685 HW43_24030 HW43_RS24685 90962 93079 - peptidase C39 gene gene4932 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24685 HW43_RS24690 HW43_24035 HW43_RS24690 93132 96128 - exotoxin paxA gene gene4933 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24690 HW43_RS24695 HW43_24040 HW43_RS24695 96130 96645 - hemolysin D gene gene4934 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24695 HW43_RS24700 HW43_24045 HW43_RS24700 96647 96865 + hypothetical protein gene gene4935 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24700 HW43_RS24705 HW43_24050 HW43_RS24705 97073 97876 - hypothetical protein gene gene4936 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24705 HW43_RS24710 HW43_24055 HW43_RS24710 97901 102229 - hemagglutinin gene gene4937 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24710 HW43_RS24715 HW43_24060 HW43_RS24715 103623 105179 + lactate permease gene gene4938 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24715 HW43_RS24720 HW43_24065 HW43_RS24720 105230 105949 + hypothetical protein gene gene4939 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24720 HW43_RS24725 HW43_24070 HW43_RS24725 105960 107375 + amino acid dehydrogenase gene gene4940 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24725 HW43_RS24730 HW43_24075 HW43_RS24730 107380 108078 + hypothetical protein gene gene4941 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24730 HW43_RS24735 HW43_24080 HW43_RS24735 108422 108853 - hypothetical protein gene gene4942 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24735 HW43_RS24740 HW43_24085 HW43_RS24740 109002 109313 - flagellar biosynthesis protein FlgM gene gene4943 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24740 HW43_RS24745 HW43_24090 HW43_RS24745 109341 109532 - hypothetical protein gene gene4944 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24745 HW43_RS24750 HW43_24095 HW43_RS24750 109542 109907 - hypothetical protein gene gene4945 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24750 HW43_RS24755 HW43_24100 HW43_RS24755 110412 114314 - autotransporter gene gene4946 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24755 HW43_RS24760 HW43_24105 HW43_RS24760 114694 115197 - thermonuclease gene gene4947 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24760 HW43_RS24765 HW43_24110 HW43_RS24765 115356 116033 + DNA-binding protein gene gene4948 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24765 HW43_RS24770 HW43_24115 HW43_RS24770 116306 116554 - hypothetical protein gene gene4949 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24770 HW43_RS24775 HW43_24120 HW43_RS24775 116901 117767 - transposase gene gene4950 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24775 HW43_RS24780 HW43_24125 HW43_RS24780 117764 118063 - transposase gene gene4951 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24780 HW43_RS24790 HW43_24140 HW43_RS24790 118561 119943 - hypothetical protein gene gene4952 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24790 HW43_RS24795 HW43_24145 HW43_RS24795 120353 120652 + transposase gene gene4953 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24795 HW43_RS24800 HW43_24150 HW43_RS24800 120649 121515 + transposase gene gene4954 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24800 HW43_RS24805 HW43_24160 HW43_RS24805 122202 122408 - hypothetical protein gene gene4955 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24805 HW43_RS24810 HW43_24165 HW43_RS24810 122347 124434 + ligand-gated channel IrgA-homologue adhesin (Iha)%3B TonB-dependent%3B acts as a specific receptor of enterobactin%3B fur-regulated%3B urovirulence factor gene gene4956 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24810 HW43_RS24815 HW43_24175 HW43_RS24815 124695 125117 - entry exclusion protein 2 gene gene4957 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24815 HW43_RS24820 HW43_24180 HW43_RS24820 125601 126026 + transposase gene gene4958 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24820 HW43_RS24825 HW43_24185 HW43_RS24825 126023 126373 + isocitrate lyase gene gene4959 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24825 HW43_RS24830 HW43_24190 HW43_RS24830 126404 127996 + transposase gene gene4960 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24830 HW43_RS24835 HW43_24195 HW43_RS24835 128218 128403 + transposase gene gene4961 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24835 HW43_RS24840 HW43_24200 HW43_RS24840 128407 128616 - resolvase gene gene4962 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24840 HW43_RS24845 HW43_24205 HW43_RS24845 129129 130172 - peptidase gene gene4963 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24845 HW43_RS24855 HW43_24220 HW43_RS24855 130789 131190 - transposase gene gene4966 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24855 HW43_RS24860 HW43_24225 HW43_RS24860 131276 131569 - transposase gene gene4967 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24860 HW43_RS24865 HW43_24230 HW43_RS24865 131566 131991 - transposase gene gene4968 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24865 HW43_RS24870 HW43_24240 HW43_RS24870 132481 133731 - hemagglutinin gene gene4969 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24870 HW43_RS24875 HW43_24245 HW43_RS24875 134406 134739 + transposase gene gene4970 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24875 HW43_RS24880 HW43_24250 HW43_RS24880 134710 135399 + transposase gene gene4971 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24880 HW43_RS24885 HW43_24255 HW43_RS24885 135828 136088 - hypothetical protein gene gene4972 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24885 HW43_RS24890 HW43_RS24890 HW43_RS24890 136081 145521 - hypothetical protein gene gene4973 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24890 HW43_RS24895 HW43_24265 HW43_RS24895 145534 147300 - peptide transporter gene gene4974 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24895 HW43_RS24900 HW43_24270 HW43_RS24900 147915 148154 - transcriptional regulator gene gene4975 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24900 HW43_RS24905 HW43_RS24905 HW43_RS24905 148275 148426 - hypothetical protein gene gene4976 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24905 HW43_RS24910 HW43_24275 HW43_RS24910 149118 149990 - hypothetical protein RepA gene gene4977 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24910 HW43_RS24915 HW43_24280 HW43_RS24915 150828 151334 + transcription termination factor NusG gene gene4978 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24915 HW43_RS24920 HW43_24285 HW43_RS24920 151475 152140 + hypothetical protein gene gene4979 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24920 HW43_RS24925 HW43_24290 HW43_RS24925 152407 153027 + membrane protein gene gene4980 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24925 HW43_RS24930 HW43_24295 HW43_RS24930 153054 154748 + membrane protein gene gene4981 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24930 HW43_RS24935 HW43_24300 HW43_RS24935 155187 155522 + hypothetical protein gene gene4982 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24935 HW43_RS24940 HW43_24305 HW43_RS24940 155556 155792 - hypothetical protein gene gene4983 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24940 HW43_RS24945 HW43_24310 HW43_RS24945 155781 156065 + hypothetical protein gene gene4984 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24945 HW43_RS24950 HW43_24315 HW43_RS24950 156129 157016 + hypothetical protein gene gene4985 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24950 HW43_RS24955 HW43_24320 HW43_RS24955 157009 157449 - membrane protein gene gene4986 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24955 HW43_RS24960 HW43_24325 HW43_RS24960 157552 158619 + type IV pilus lipoprotein gene gene4987 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24960 HW43_RS24965 HW43_24330 HW43_RS24965 158624 159061 + hypothetical protein gene gene4988 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24965 HW43_RS24970 HW43_24335 HW43_RS24970 159092 160711 + hypothetical protein gene gene4989 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24970 HW43_RS24975 HW43_RS24975 HW43_RS24975 160732 161447 + pilus assembly protein gene gene4990 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24975 HW43_RS24980 HW43_RS24980 HW43_RS24980 2860602 2862220 + adhesin gene gene2831 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24980 HW43_RS24985 HW43_RS24985 HW43_RS24985 2863102 2863353 + hypothetical protein gene gene2832 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24985 HW43_RS24990 HW43_RS24990 HW43_RS24990 2863354 2863593 + hypothetical protein gene gene2833 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24990 HW43_RS24995 HW43_RS24995 HW43_RS24995 3059914 3061626 - phage tail protein gene gene3005 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS24995 HW43_RS25000 HW43_RS25000 HW43_RS25000 3350203 3350439 + type VI secretion protein gene gene3306 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS25000 HW43_RS25005 HW43_RS25005 HW43_RS25005 4054494 4054800 - transposase gene gene3997 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS25005 HW43_RS25010 HW43_RS25010 HW43_RS25010 4054810 4054995 + hypothetical protein gene gene3998 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS25010 HW43_RS25015 HW43_RS25015 HW43_RS25015 87220 87450 - serine/threonine protein kinase gene gene4927 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS25015 HW43_RS25020 HW43_24210 HW43_RS25020 130226 130411 - transposase gene gene4964 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS25020 HW43_RS25025 HW43_24215 HW43_RS25025 130387 130716 - hypothetical protein gene gene4965 http://www.ncbi.nlm.nih.gov/gene/?term=HW43_RS25025