locus-tag	class	description
HVY91_RS00025	COG4695	Portal protein
HVY91_RS00120	COG5301	cellulose 1,4-beta-cellobiosidase activity
HVY91_RS00120	COG5301	cellulose 1,4-beta-cellobiosidase activity
HVY91_RS00175	COG1882	Formate acetyltransferase
HVY91_RS00180	COG2116	formate transmembrane transporter activity
HVY91_RS00185	COG1944	ATP diphosphatase activity
HVY91_RS00190	COG2323	membrane
HVY91_RS00210	COG0539	negative regulation of cytoplasmic translation
HVY91_RS00220	COG2333	competence protein COMEC
HVY91_RS00220	COG0658	competence protein
HVY91_RS00235	COG3214	Protein conserved in bacteria
HVY91_RS00250	COG3173	Aminoglycoside phosphotransferase
HVY91_RS00255	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HVY91_RS00260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HVY91_RS00270	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HVY91_RS00280	COG2989	Protein conserved in bacteria
HVY91_RS00285	COG3108	Peptidase M15
HVY91_RS00290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HVY91_RS00295	COG1448	Aminotransferase
HVY91_RS00315	COG0308	aminopeptidase N
HVY91_RS00320	COG1116	anion transmembrane transporter activity
HVY91_RS00325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HVY91_RS00335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HVY91_RS00340	COG0431	NADPH-dependent FMN reductase
HVY91_RS00365	COG0488	(ABC) transporter
HVY91_RS00370	COG2995	paraquat-inducible protein a
HVY91_RS00375	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HVY91_RS00375	COG3008	intermembrane lipid transfer
HVY91_RS00380	COG3009	Protein conserved in bacteria
HVY91_RS00385	COG3130	regulation of translation
HVY91_RS00395	COG1067	ATP-dependent peptidase activity
HVY91_RS00415	COG3070	regulator of competence-specific genes
HVY91_RS00420	COG1289	transmembrane transporter activity
HVY91_RS00425	COG3304	Inner membrane component domain
HVY91_RS00430	COG0210	DNA helicase
HVY91_RS00445	COG1832	CoA-binding protein
HVY91_RS00460	COG1254	Belongs to the acylphosphatase family
HVY91_RS00465	COG2920	part of a sulfur-relay system
HVY91_RS00470	COG0670	Belongs to the BI1 family
HVY91_RS00485	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HVY91_RS00490	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HVY91_RS00495	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
HVY91_RS00500	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HVY91_RS00505	COG1999	signal sequence binding
HVY91_RS00510	COG1773	rubredoxin
HVY91_RS00515	COG3012	SEC-C Motif Domain Protein
HVY91_RS00515	COG3318	Belongs to the UPF0149 family
HVY91_RS00520	COG0814	amino acid
HVY91_RS00530	COG1528	Iron-storage protein
HVY91_RS00540	COG1528	Iron-storage protein
HVY91_RS00545	COG1879	ABC-type sugar transport system periplasmic component
HVY91_RS00550	COG1129	ABC transporter
HVY91_RS00555	COG1172	Belongs to the binding-protein-dependent transport system permease family
HVY91_RS00560	COG1877	trehalose-phosphatase activity
HVY91_RS00570	COG0589	response to stress
HVY91_RS00585	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HVY91_RS00595	COG2198	Histidine kinase
HVY91_RS00595	COG0643	Histidine kinase
HVY91_RS00630	COG0840	transmembrane signaling receptor activity
HVY91_RS00645	COG0745	RESPONSE REGULATOR receiver
HVY91_RS00675	COG0583	DNA-binding transcription factor activity
HVY91_RS00700	COG3729	General stress protein
HVY91_RS00705	COG1309	transcriptional regulator
HVY91_RS00710	COG2200	EAL domain
HVY91_RS00715	COG2199	diguanylate cyclase activity
HVY91_RS00725	COG1215	transferase activity, transferring glycosyl groups
HVY91_RS00730	COG0425	Belongs to the sulfur carrier protein TusA family
HVY91_RS00735	COG2391	methyltransferase activity
HVY91_RS00745	COG0366	Alpha amylase catalytic
HVY91_RS00800	COG2197	response regulator
HVY91_RS00810	COG2197	response regulator
HVY91_RS00840	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HVY91_RS00845	COG1271	oxidase subunit
HVY91_RS00850	COG1294	oxidase, subunit
HVY91_RS00865	COG0784	Response regulator, receiver
HVY91_RS00865	COG2205	protein histidine kinase activity
HVY91_RS00865	COG2198	Histidine kinase
HVY91_RS00870	COG1879	ABC-type sugar transport system periplasmic component
HVY91_RS00875	COG0745	RESPONSE REGULATOR receiver
HVY91_RS00880	COG3005	denitrification pathway
HVY91_RS00885	COG0243	molybdopterin cofactor binding
HVY91_RS00900	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HVY91_RS00915	COG3102	Protein conserved in bacteria
HVY91_RS00935	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HVY91_RS00940	COG1801	Protein of unknown function DUF72
HVY91_RS00945	COG1335	isochorismatase
HVY91_RS00955	COG0494	nUDIX hydrolase
HVY91_RS00960	COG0217	transcriptional regulatory protein
HVY91_RS00990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HVY91_RS01000	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HVY91_RS01005	COG0739	heme binding
HVY91_RS01010	COG1560	Kdo2-lipid A biosynthetic process
HVY91_RS01015	COG0469	pyruvate kinase activity
HVY91_RS01020	COG1737	Transcriptional regulator
HVY91_RS01025	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HVY91_RS01030	COG0129	dihydroxy-acid dehydratase activity
HVY91_RS01035	COG0800	Aldolase
HVY91_RS01045	COG3141	response to X-ray
HVY91_RS01055	COG2979	Protein of unknown function (DUF533)
HVY91_RS01060	COG1770	oligopeptidase
HVY91_RS01065	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HVY91_RS01070	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HVY91_RS01080	COG2372	response to copper ion
HVY91_RS01085	COG1276	copper resistance
HVY91_RS01095	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HVY91_RS01115	COG3008	intermembrane lipid transfer
HVY91_RS01120	COG2995	paraquat-inducible protein a
HVY91_RS01125	COG1956	GAF domain-containing protein
HVY91_RS01145	COG2814	Major facilitator Superfamily
HVY91_RS01150	COG1414	Transcriptional regulator
HVY91_RS01180	COG2226	methyltransferase
HVY91_RS01195	COG3716	PTS system mannose fructose sorbose family IID component
HVY91_RS01200	COG3715	PTS system
HVY91_RS01205	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVY91_RS01205	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVY91_RS01210	COG1253	flavin adenine dinucleotide binding
HVY91_RS01215	COG2200	EAL domain
HVY91_RS01220	COG1760	l-serine dehydratase
HVY91_RS01230	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HVY91_RS01250	COG0251	oxidation-reduction process
HVY91_RS01265	COG1199	ATP-dependent helicase activity
HVY91_RS01270	COG1214	PFAM Peptidase M22, glycoprotease
HVY91_RS01275	COG3065	identical protein binding
HVY91_RS01280	COG0318	PFAM AMP-dependent synthetase and ligase
HVY91_RS01285	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HVY91_RS01290	COG1376	ErfK ybiS ycfS ynhG family protein
HVY91_RS01290	COG1388	LysM domain
HVY91_RS01295	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HVY91_RS01300	COG4763	Acyl-transferase
HVY91_RS01305	COG4591	ABC-type transport system involved in lipoprotein release permease component
HVY91_RS01315	COG4591	ABC-type transport system involved in lipoprotein release permease component
HVY91_RS01325	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HVY91_RS01330	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HVY91_RS01340	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HVY91_RS01345	COG1177	transmembrane transport
HVY91_RS01380	COG3139	Protein of unknown function (DUF1315)
HVY91_RS01385	COG1335	isochorismatase
HVY91_RS01390	COG0252	asparaginase activity
HVY91_RS01400	COG0616	signal peptide processing
HVY91_RS01405	COG0778	Nitroreductase
HVY91_RS01415	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HVY91_RS01420	COG0443	Heat shock 70 kDa protein
HVY91_RS01440	COG0494	nUDIX hydrolase
HVY91_RS01445	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HVY91_RS01450	COG2897	thiosulfate sulfurtransferase activity
HVY91_RS01455	COG4136	ATPase activity
HVY91_RS01460	COG4135	transport system, permease component
HVY91_RS01465	COG4134	Bacterial extracellular solute-binding protein
HVY91_RS01470	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HVY91_RS01475	COG0398	Pfam SNARE associated Golgi protein
HVY91_RS01480	COG0398	Pfam SNARE associated Golgi protein
HVY91_RS01485	COG0708	Exodeoxyribonuclease III
HVY91_RS01515	COG3678	ATP-independent chaperone mediated protein folding
HVY91_RS01525	COG0322	excinuclease ABC activity
HVY91_RS01535	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HVY91_RS01540	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HVY91_RS01545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HVY91_RS01550	COG1447	Phosphotransferase system cellobiose-specific component IIA
HVY91_RS01555	COG1917	Cupin 2, conserved barrel domain protein
HVY91_RS01555	COG2169	Transcriptional regulator
HVY91_RS01560	COG1486	melibiose metabolic process
HVY91_RS01570	COG0753	catalase activity
HVY91_RS01585	COG1988	membrane-bound metal-dependent
HVY91_RS01590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HVY91_RS01600	COG3001	Fructosamine kinase
HVY91_RS01610	COG1105	Belongs to the carbohydrate kinase PfkB family
HVY91_RS01615	COG3137	Salt-induced outer membrane protein
HVY91_RS01675	COG0791	NLP P60 protein
HVY91_RS01690	COG4256	Hemin uptake protein
HVY91_RS01695	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HVY91_RS01705	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HVY91_RS01705	COG0574	Belongs to the PEP-utilizing enzyme family
HVY91_RS01720	COG0628	permease
HVY91_RS01725	COG0277	FAD linked oxidase domain protein
HVY91_RS01725	COG0247	lactate metabolic process
HVY91_RS01730	COG2050	protein possibly involved in aromatic compounds catabolism
HVY91_RS01740	COG0316	Belongs to the HesB IscA family
HVY91_RS01745	COG0719	Fe-S assembly protein
HVY91_RS01750	COG0396	ATPase activity
HVY91_RS01755	COG0719	Fe-S assembly protein
HVY91_RS01770	COG1376	ErfK ybiS ycfS ynhG family protein
HVY91_RS01775	COG4238	major outer membrane lipoprotein
HVY91_RS01780	COG0469	pyruvate kinase activity
HVY91_RS01790	COG4529	Protein conserved in bacteria
HVY91_RS01815	COG0307	riboflavin synthase, alpha
HVY91_RS01820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HVY91_RS01825	COG2814	Major facilitator Superfamily
HVY91_RS01830	COG0583	DNA-binding transcription factor activity
HVY91_RS01845	COG2814	Major facilitator Superfamily
HVY91_RS01850	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HVY91_RS01855	COG0791	NLP P60 protein
HVY91_RS01860	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HVY91_RS01865	COG1201	RNA secondary structure unwinding
HVY91_RS01875	COG0346	lactoylglutathione lyase activity
HVY91_RS01880	COG1902	pentaerythritol trinitrate reductase activity
HVY91_RS01885	COG1309	transcriptional regulator
HVY91_RS01890	COG3313	Fe-S protein
HVY91_RS01895	COG4989	oxidoreductase activity
HVY91_RS01900	COG2032	superoxide dismutase activity
HVY91_RS01905	COG1289	transmembrane transporter activity
HVY91_RS01910	COG1566	PFAM secretion protein HlyD family protein
HVY91_RS01925	COG3133	Outer membrane lipoprotein
HVY91_RS01935	COG3895	Periplasmic Protein
HVY91_RS01955	COG0625	glutathione transferase activity
HVY91_RS01960	COG3104	oligopeptide transport
HVY91_RS01965	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HVY91_RS01975	COG4659	FMN binding
HVY91_RS02015	COG0673	inositol 2-dehydrogenase activity
HVY91_RS02025	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HVY91_RS02030	COG5339	Protein conserved in bacteria
HVY91_RS02035	COG1482	cell wall glycoprotein biosynthetic process
HVY91_RS02040	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HVY91_RS02040	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HVY91_RS02045	COG0114	fumarate hydratase activity
HVY91_RS02055	COG2205	protein histidine kinase activity
HVY91_RS02060	COG0745	RESPONSE REGULATOR receiver
HVY91_RS02065	COG3136	membrane protein required for alginate biosynthesis
HVY91_RS02075	COG0531	amino acid
HVY91_RS02085	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HVY91_RS02090	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HVY91_RS02100	COG3591	Belongs to the peptidase S1B family
HVY91_RS02115	COG2814	Major facilitator Superfamily
HVY91_RS02120	COG0583	DNA-binding transcription factor activity
HVY91_RS02125	COG1940	carbohydrate kinase activity
HVY91_RS02130	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HVY91_RS02165	COG3238	Protein conserved in bacteria
HVY91_RS02170	COG1247	-acetyltransferase
HVY91_RS02175	COG2130	NADP-dependent
HVY91_RS02180	COG1802	Transcriptional regulator
HVY91_RS02185	COG4772	TonB-dependent receptor
HVY91_RS02190	COG3391	amine dehydrogenase activity
HVY91_RS02195	COG1113	amino acid transport
HVY91_RS02200	COG0625	glutathione transferase activity
HVY91_RS02265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HVY91_RS02275	COG0384	phenazine biosynthesis protein PhzF
HVY91_RS02285	COG1609	Transcriptional regulator
HVY91_RS02295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HVY91_RS02300	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HVY91_RS02305	COG1414	Transcriptional regulator
HVY91_RS02310	COG4948	Mandelate Racemase Muconate Lactonizing
HVY91_RS02315	COG4829	muconolactone delta-isomerase
HVY91_RS02320	COG3485	protocatechuate 3,4-dioxygenase
HVY91_RS02355	COG0697	spore germination
HVY91_RS02365	COG0437	4 iron, 4 sulfur cluster binding
HVY91_RS02370	COG2864	formate dehydrogenase
HVY91_RS02375	COG3093	addiction module antidote protein HigA
HVY91_RS02385	COG1064	alcohol dehydrogenase
HVY91_RS02405	COG1764	response to oxidative stress
HVY91_RS02415	COG0583	DNA-binding transcription factor activity
HVY91_RS02420	COG3485	protocatechuate 3,4-dioxygenase
HVY91_RS02425	COG3485	protocatechuate 3,4-dioxygenase
HVY91_RS02430	COG5383	Protein conserved in bacteria
HVY91_RS02440	COG2841	Protein conserved in bacteria
HVY91_RS02445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HVY91_RS02450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HVY91_RS02455	COG0500	methyltransferase
HVY91_RS02465	COG0826	peptidase U32
HVY91_RS02480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HVY91_RS02485	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HVY91_RS02490	COG3842	ATPase activity
HVY91_RS02495	COG1176	ABC-type spermidine putrescine transport system, permease component I
HVY91_RS02500	COG1177	transmembrane transport
HVY91_RS02530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HVY91_RS02545	COG4948	Mandelate Racemase Muconate Lactonizing
HVY91_RS02550	COG1063	alcohol dehydrogenase
HVY91_RS02555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HVY91_RS02565	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HVY91_RS02570	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HVY91_RS02575	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HVY91_RS02575	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HVY91_RS02585	COG0246	Mannitol dehydrogenase
HVY91_RS02595	COG1802	Transcriptional regulator
HVY91_RS02600	COG4221	oxidoreductase activity
HVY91_RS02605	COG0339	signal peptide processing
HVY91_RS02610	COG1546	Belongs to the CinA family
HVY91_RS02615	COG3111	PFAM Bacterial OB fold (BOF) protein
HVY91_RS02620	COG3706	GGDEF domain
HVY91_RS02625	COG2814	Major facilitator Superfamily
HVY91_RS02630	COG0697	spore germination
HVY91_RS02640	COG4977	sequence-specific DNA binding
HVY91_RS02645	COG1846	Transcriptional regulator
HVY91_RS02660	COG0583	DNA-binding transcription factor activity
HVY91_RS02665	COG1012	belongs to the aldehyde dehydrogenase family
HVY91_RS02670	COG2066	Belongs to the glutaminase family
HVY91_RS02680	COG2199	diguanylate cyclase activity
HVY91_RS02690	COG3781	membrane
HVY91_RS02745	COG2207	Transcriptional regulator
HVY91_RS02765	COG4178	(ABC) transporter
HVY91_RS02770	COG4771	TonB-dependent receptor
HVY91_RS02775	COG0612	Peptidase, M16
HVY91_RS02780	COG0076	glutamate decarboxylase activity
HVY91_RS02785	COG0531	amino acid
HVY91_RS02800	COG2200	EAL domain
HVY91_RS02800	COG2199	diguanylate cyclase activity
HVY91_RS02800	COG2202	Pas domain
HVY91_RS02815	COG3038	cytochrome b561
HVY91_RS02820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HVY91_RS02855	COG1643	Atp-dependent helicase
HVY91_RS02865	COG2453	phosphatase
HVY91_RS02865	COG0671	phosphoesterase, PA-phosphatase related
HVY91_RS02870	COG2267	carboxylic ester hydrolase activity
HVY91_RS02875	COG4589	Belongs to the CDS family
HVY91_RS02880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HVY91_RS02890	COG0667	Aldo Keto reductase
HVY91_RS02895	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HVY91_RS02900	COG3327	negative regulation of DNA-templated transcription, initiation
HVY91_RS02905	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HVY91_RS02910	COG0183	Belongs to the thiolase family
HVY91_RS02915	COG2050	protein possibly involved in aromatic compounds catabolism
HVY91_RS02920	COG1250	3-hydroxyacyl-CoA dehydrogenase
HVY91_RS02925	COG1024	Enoyl-CoA hydratase
HVY91_RS02930	COG1024	Enoyl-CoA hydratase
HVY91_RS02935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HVY91_RS02940	COG2151	metal-sulfur cluster biosynthetic enzyme
HVY91_RS02945	COG3396	Phenylacetate-CoA oxygenase
HVY91_RS02950	COG3460	Phenylacetate-CoA oxygenase
HVY91_RS02955	COG3396	Phenylacetate-CoA oxygenase
HVY91_RS02960	COG2030	dehydratase
HVY91_RS02960	COG1012	belongs to the aldehyde dehydrogenase family
HVY91_RS02965	COG3733	amine oxidase
HVY91_RS02970	COG1012	belongs to the aldehyde dehydrogenase family
HVY91_RS02975	COG2207	Transcriptional regulator
HVY91_RS02985	COG3784	Protein of unknown function (DUF1318)
HVY91_RS02995	COG2911	Protein conserved in bacteria
HVY91_RS03000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HVY91_RS03005	COG3187	Heat shock protein
HVY91_RS03010	COG3042	response to heat
HVY91_RS03020	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HVY91_RS03020	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HVY91_RS03020	COG1013	pyruvate-flavodoxin oxidoreductase activity
HVY91_RS03020	COG0674	pyruvate-flavodoxin oxidoreductase activity
HVY91_RS03025	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HVY91_RS03030	COG0589	response to stress
HVY91_RS03040	COG0513	Belongs to the DEAD box helicase family
HVY91_RS03055	COG3706	GGDEF domain
HVY91_RS03060	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HVY91_RS03065	COG0596	Alpha beta hydrolase
HVY91_RS03075	COG0183	Belongs to the thiolase family
HVY91_RS03080	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HVY91_RS03090	COG1414	Transcriptional regulator
HVY91_RS03095	COG2840	Smr protein MutS2
HVY91_RS03100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HVY91_RS03105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HVY91_RS03110	COG0589	response to stress
HVY91_RS03115	COG3182	Iron-regulated membrane protein
HVY91_RS03120	COG0668	transmembrane transport
HVY91_RS03125	COG4166	transmembrane transport
HVY91_RS03130	COG2866	Carboxypeptidase
HVY91_RS03135	COG4948	Mandelate Racemase Muconate Lactonizing
HVY91_RS03140	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HVY91_RS03145	COG3283	Transcriptional regulator of aromatic amino acids metabolism
HVY91_RS03155	COG3106	COG3106 Predicted ATPase
HVY91_RS03160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HVY91_RS03170	COG1983	PspC domain protein
HVY91_RS03180	COG1842	Phage shock protein A
HVY91_RS03185	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HVY91_RS03190	COG4166	transmembrane transport
HVY91_RS03195	COG4168	peptide transport system, permease
HVY91_RS03200	COG4171	peptide transport system, permease
HVY91_RS03205	COG4172	Belongs to the ABC transporter superfamily
HVY91_RS03210	COG4172	Belongs to the ABC transporter superfamily
HVY91_RS03215	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HVY91_RS03220	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HVY91_RS03220	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HVY91_RS03230	COG5001	Diguanylate cyclase
HVY91_RS03240	COG1349	DNA-binding transcription factor activity
HVY91_RS03250	COG0023	Translation Initiation Factor
HVY91_RS03260	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HVY91_RS03265	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HVY91_RS03270	COG0671	phosphoesterase, PA-phosphatase related
HVY91_RS03300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HVY91_RS03310	COG0616	signal peptide processing
HVY91_RS03315	COG1028	Short-chain dehydrogenase reductase Sdr
HVY91_RS03320	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HVY91_RS03325	COG1187	pseudouridine synthase activity
HVY91_RS03330	COG4907	membrane protein (DUF2207)
HVY91_RS03335	COG0009	L-threonylcarbamoyladenylate synthase
HVY91_RS03340	COG0613	PHP domain protein
HVY91_RS03350	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HVY91_RS03355	COG0512	Glutamine amidotransferase of anthranilate synthase
HVY91_RS03355	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HVY91_RS03360	COG0135	phosphoribosylanthranilate isomerase activity
HVY91_RS03360	COG0134	indole-3-glycerol-phosphate synthase activity
HVY91_RS03370	COG0159	tryptophan synthase activity
HVY91_RS03375	COG3047	cAMP biosynthetic process
HVY91_RS03380	COG0727	PFAM Uncharacterised protein family (UPF0153)
HVY91_RS03395	COG1607	acyl-coa hydrolase
HVY91_RS03405	COG2350	Protein conserved in bacteria
HVY91_RS03430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HVY91_RS03435	COG4608	Belongs to the ABC transporter superfamily
HVY91_RS03440	COG0444	Belongs to the ABC transporter superfamily
HVY91_RS03460	COG2095	MarC family integral membrane protein
HVY91_RS03465	COG1454	alcohol dehydrogenase
HVY91_RS03465	COG1012	belongs to the aldehyde dehydrogenase family
HVY91_RS03475	COG1435	thymidine kinase activity
HVY91_RS03485	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HVY91_RS03490	COG0745	RESPONSE REGULATOR receiver
HVY91_RS03495	COG1752	Esterase of the alpha-beta hydrolase superfamily
HVY91_RS03505	COG0788	formyltetrahydrofolate deformylase activity
HVY91_RS03555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HVY91_RS03560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HVY91_RS03565	COG2181	nitrate reductase activity
HVY91_RS03570	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HVY91_RS03575	COG1140	nitrate reductase beta subunit
HVY91_RS03580	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HVY91_RS03585	COG2223	nitrite transmembrane transporter activity
HVY91_RS03590	COG3850	Histidine kinase
HVY91_RS03595	COG2197	response regulator
HVY91_RS03600	COG4932	domain protein
HVY91_RS03605	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HVY91_RS03610	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HVY91_RS03615	COG4572	Cation transport regulator
HVY91_RS03620	COG0387	Pfam Sodium calcium exchanger
HVY91_RS03640	COG2890	protein-(glutamine-N5) methyltransferase activity
HVY91_RS03665	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HVY91_RS03670	COG0659	secondary active sulfate transmembrane transporter activity
HVY91_RS03685	COG0012	GTP binding
HVY91_RS03700	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HVY91_RS03710	COG1619	proteins homologs of microcin C7 resistance protein MccF
HVY91_RS03720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HVY91_RS03730	COG2719	SpoVR family
HVY91_RS03745	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HVY91_RS03750	COG1388	LysM domain
HVY91_RS03750	COG1470	cell adhesion involved in biofilm formation
HVY91_RS03760	COG0179	Fumarylacetoacetate (FAA) hydrolase
HVY91_RS03775	COG2894	cell division
HVY91_RS03785	COG1124	(ABC) transporter
HVY91_RS03795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HVY91_RS03800	COG0601	transmembrane transport
HVY91_RS03805	COG0747	negative chemotaxis
HVY91_RS03815	COG1473	amidohydrolase
HVY91_RS03825	COG0217	transcriptional regulatory protein
HVY91_RS03835	COG4932	domain protein
HVY91_RS03835	COG2373	Large extracellular alpha-helical protein
HVY91_RS03835	COG1388	LysM domain
HVY91_RS03855	COG0582	viral genome integration into host DNA
HVY91_RS03860	COG0538	isocitrate dehydrogenase activity
HVY91_RS03865	COG1187	pseudouridine synthase activity
HVY91_RS03885	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HVY91_RS03890	COG0745	RESPONSE REGULATOR receiver
HVY91_RS03895	COG2205	protein histidine kinase activity
HVY91_RS03900	COG2850	peptidyl-arginine hydroxylation
HVY91_RS03905	COG0656	L-ascorbic acid biosynthetic process
HVY91_RS03910	COG3713	MltA-interacting MipA family protein
HVY91_RS03915	COG2766	serine protein kinase
HVY91_RS03925	COG2199	diguanylate cyclase activity
HVY91_RS03930	COG2199	diguanylate cyclase activity
HVY91_RS03935	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HVY91_RS03950	COG2807	transmembrane transport
HVY91_RS03955	COG3189	MarR family transcriptional regulator
HVY91_RS03960	COG3042	response to heat
HVY91_RS03965	COG2199	diguanylate cyclase activity
HVY91_RS03965	COG2203	Gaf domain
HVY91_RS03980	COG2261	transglycosylase associated protein
HVY91_RS03990	COG3134	Outer membrane lipoprotein
HVY91_RS03995	COG1252	NADH dehydrogenase
HVY91_RS04010	COG0510	thiamine kinase activity
HVY91_RS04015	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
HVY91_RS04020	COG5633	Lipoprotein
HVY91_RS04025	COG0537	adenosine 5'-monophosphoramidase activity
HVY91_RS04035	COG0084	hydrolase, TatD family'
HVY91_RS04040	COG0470	DNA polymerase III
HVY91_RS04050	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HVY91_RS04055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HVY91_RS04060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HVY91_RS04070	COG1028	Short-chain dehydrogenase reductase Sdr
HVY91_RS04075	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HVY91_RS04095	COG1399	metal-binding, possibly nucleic acid-binding protein
HVY91_RS04100	COG0424	maF-like protein
HVY91_RS04105	COG0564	pseudouridine synthase activity
HVY91_RS04110	COG1530	ribonuclease E activity
HVY91_RS04115	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HVY91_RS04120	COG1256	bacterial-type flagellum assembly
HVY91_RS04125	COG3951	Flagellar rod assembly protein muramidase FlgJ
HVY91_RS04125	COG1705	Flagellar rod assembly protein muramidase FlgJ
HVY91_RS04145	COG4787	bacterial-type flagellum-dependent cell motility
HVY91_RS04150	COG1749	Flagellar hook protein flgE
HVY91_RS04155	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HVY91_RS04160	COG1558	bacterial-type flagellum-dependent cell motility
HVY91_RS04175	COG2747	anti-sigma28 factor FlgM
HVY91_RS04185	COG0728	peptidoglycan biosynthetic process
HVY91_RS04190	COG0673	inositol 2-dehydrogenase activity
HVY91_RS04200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HVY91_RS04235	COG3038	cytochrome b561
HVY91_RS04240	COG2353	YceI-like domain
HVY91_RS04250	COG1560	Kdo2-lipid A biosynthetic process
HVY91_RS04265	COG5645	(Lipo)protein
HVY91_RS04270	COG2943	transferase activity, transferring hexosyl groups
HVY91_RS04285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HVY91_RS04330	COG1462	curli production assembly transport component CsgG
HVY91_RS04340	COG3381	protein complex oligomerization
HVY91_RS04360	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HVY91_RS04365	COG3104	oligopeptide transport
HVY91_RS04370	COG1982	Orn Lys Arg decarboxylase major
HVY91_RS04375	COG0531	amino acid
HVY91_RS04380	COG3710	Transcriptional regulator
HVY91_RS04385	COG3706	GGDEF domain
HVY91_RS04390	COG0457	Tetratricopeptide repeat
HVY91_RS04395	COG0726	polysaccharide deacetylase
HVY91_RS04395	COG1649	PFAM Uncharacterised BCR, COG1649
HVY91_RS04400	COG1215	transferase activity, transferring glycosyl groups
HVY91_RS04405	COG3658	cytochrome
HVY91_RS04410	COG1702	phosphate starvation-inducible protein PhoH
HVY91_RS04420	COG2822	iron ion transport
HVY91_RS04430	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HVY91_RS04440	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HVY91_RS04440	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HVY91_RS04440	COG0506	proline dehydrogenase activity
HVY91_RS04445	COG1560	Kdo2-lipid A biosynthetic process
HVY91_RS04450	COG2990	Protein conserved in bacteria
HVY91_RS04455	COG0438	transferase activity, transferring glycosyl groups
HVY91_RS04460	COG0726	polysaccharide deacetylase
HVY91_RS04465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HVY91_RS04470	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HVY91_RS04480	COG1766	The M ring may be actively involved in energy transduction
HVY91_RS04485	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HVY91_RS04490	COG1317	bacterial-type flagellum organization
HVY91_RS04495	COG1157	protein secretion by the type III secretion system
HVY91_RS04500	COG2882	bacterial-type flagellum organization
HVY91_RS04505	COG3144	bacterial-type flagellum assembly
HVY91_RS04510	COG1580	Controls the rotational direction of flagella during chemotaxis
HVY91_RS04515	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HVY91_RS04520	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HVY91_RS04525	COG3190	flagellar
HVY91_RS04530	COG1338	Plays a role in the flagellum-specific transport system
HVY91_RS04545	COG2197	response regulator
HVY91_RS04570	COG5475	Uncharacterized small protein (DUF2158)
HVY91_RS04575	COG2354	Protein conserved in bacteria
HVY91_RS04580	COG0697	spore germination
HVY91_RS04585	COG3727	T/G mismatch-specific endonuclease activity
HVY91_RS04590	COG1418	mRNA catabolic process
HVY91_RS04600	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HVY91_RS04610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HVY91_RS04635	COG0583	DNA-binding transcription factor activity
HVY91_RS04680	COG3157	Type VI secretion system effector, Hcp
HVY91_RS04760	COG3501	Rhs element vgr protein
HVY91_RS04800	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HVY91_RS04805	COG0477	Major facilitator Superfamily
HVY91_RS04815	COG0534	Mate efflux family protein
HVY91_RS04855	COG1454	alcohol dehydrogenase
HVY91_RS04855	COG1012	belongs to the aldehyde dehydrogenase family
HVY91_RS04865	COG1012	belongs to the aldehyde dehydrogenase family
HVY91_RS04865	COG1454	alcohol dehydrogenase
HVY91_RS04870	COG1882	Formate acetyltransferase
HVY91_RS04875	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HVY91_RS04885	COG4869	propanediol catabolic process
HVY91_RS04905	COG1376	ErfK ybiS ycfS ynhG family protein
HVY91_RS05005	COG4656	Part of a membrane complex involved in electron transport
HVY91_RS05035	COG1289	transmembrane transporter activity
HVY91_RS05045	COG2925	Exonuclease
HVY91_RS05050	COG0425	Belongs to the sulfur carrier protein TusA family
HVY91_RS05055	COG2391	methyltransferase activity
HVY91_RS05060	COG0531	amino acid
HVY91_RS05070	COG0583	DNA-binding transcription factor activity
HVY91_RS05075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HVY91_RS05080	COG4115	mRNA cleavage
HVY91_RS05085	COG2161	toxin-antitoxin pair type II binding
HVY91_RS05100	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HVY91_RS05110	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HVY91_RS05110	COG0131	Imidazoleglycerol-phosphate dehydratase
HVY91_RS05115	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HVY91_RS05140	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HVY91_RS05145	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HVY91_RS05160	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HVY91_RS05170	COG1086	Polysaccharide biosynthesis protein
HVY91_RS05175	COG0438	transferase activity, transferring glycosyl groups
HVY91_RS05180	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HVY91_RS05180	COG1215	transferase activity, transferring glycosyl groups
HVY91_RS05200	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HVY91_RS05210	COG0438	transferase activity, transferring glycosyl groups
HVY91_RS05215	COG2327	Polysaccharide pyruvyl transferase
HVY91_RS05220	COG2244	polysaccharide biosynthetic process
HVY91_RS05225	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HVY91_RS05230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HVY91_RS05235	COG0662	Cupin 2, conserved barrel domain protein
HVY91_RS05235	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HVY91_RS05240	COG0297	glycogen (starch) synthase activity
HVY91_RS05245	COG1051	belongs to the nudix hydrolase family
HVY91_RS05250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HVY91_RS05255	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HVY91_RS05260	COG0110	maltose O-acetyltransferase activity
HVY91_RS05265	COG1216	Glycosyl transferase, family 2
HVY91_RS05275	COG0438	transferase activity, transferring glycosyl groups
HVY91_RS05280	COG1045	serine acetyltransferase
HVY91_RS05285	COG0463	Glycosyl transferase, family 2
HVY91_RS05290	COG0489	protein tyrosine kinase activity
HVY91_RS05290	COG3206	protein involved in exopolysaccharide biosynthesis
HVY91_RS05295	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HVY91_RS05300	COG1596	polysaccharide export
HVY91_RS05305	COG1253	flavin adenine dinucleotide binding
HVY91_RS05325	COG2982	Protein involved in outer membrane biogenesis
HVY91_RS05340	COG3447	MASE1 domain protein
HVY91_RS05340	COG5002	protein histidine kinase activity
HVY91_RS05340	COG5001	Diguanylate cyclase
HVY91_RS05345	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HVY91_RS05350	COG0443	Heat shock 70 kDa protein
HVY91_RS05355	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
HVY91_RS05360	COG3779	Protein conserved in bacteria
HVY91_RS05365	COG0631	protein serine/threonine phosphatase activity
HVY91_RS05370	COG4245	von Willebrand factor, type A
HVY91_RS05405	COG2205	protein histidine kinase activity
HVY91_RS05410	COG0745	RESPONSE REGULATOR receiver
HVY91_RS05420	COG3609	addiction module antidote protein, CC2985 family
HVY91_RS05440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HVY91_RS05450	COG1070	Carbohydrate kinase
HVY91_RS05475	COG1069	ribulokinase activity
HVY91_RS05485	COG1830	Aldolase
HVY91_RS05490	COG2211	Major facilitator Superfamily
HVY91_RS05495	COG1397	ADP-ribosylglycohydrolase
HVY91_RS05500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVY91_RS05505	COG2188	Transcriptional regulator
HVY91_RS05510	COG3757	hydrolase, family 25
HVY91_RS05515	COG0351	phosphomethylpyrimidine kinase
HVY91_RS05525	COG5455	response to cobalt ion
HVY91_RS05530	COG3539	Fimbrial protein
HVY91_RS05535	COG3188	usher protein
HVY91_RS05540	COG3121	Chaperone
HVY91_RS05555	COG0489	protein tyrosine kinase activity
HVY91_RS05565	COG3831	ATPase activity
HVY91_RS05570	COG3831	ATPase activity
HVY91_RS05575	COG3831	ATPase activity
HVY91_RS05580	COG3831	ATPase activity
HVY91_RS05590	COG0714	Associated with various cellular activities
HVY91_RS05595	COG2425	protein containing a von Willebrand factor type A (vWA) domain
HVY91_RS05600	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HVY91_RS05610	COG4808	Protein conserved in bacteria
HVY91_RS05615	COG4807	Protein conserved in bacteria
HVY91_RS05625	COG3275	phosphorelay sensor kinase activity
HVY91_RS05630	COG0789	Transcriptional regulator
HVY91_RS05640	COG1174	glycine betaine transport
HVY91_RS05645	COG1125	glycine betaine transport
HVY91_RS05650	COG1174	glycine betaine transport
HVY91_RS05655	COG1732	Glycine betaine
HVY91_RS05660	COG1472	Belongs to the glycosyl hydrolase 3 family
HVY91_RS05665	COG0277	FAD linked oxidase domain protein
HVY91_RS05670	COG1686	Belongs to the peptidase S11 family
HVY91_RS05680	COG0586	Pfam SNARE associated Golgi protein
HVY91_RS05685	COG1028	Short-chain dehydrogenase reductase Sdr
HVY91_RS05695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HVY91_RS05705	COG1346	cytolysis
HVY91_RS05715	COG2949	membrane
HVY91_RS05725	COG0493	'glutamate synthase
HVY91_RS05730	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HVY91_RS05730	COG0167	dihydroorotate dehydrogenase activity
HVY91_RS05735	COG4211	Belongs to the binding-protein-dependent transport system permease family
HVY91_RS05740	COG1129	ABC transporter
HVY91_RS05745	COG1879	ABC-type sugar transport system periplasmic component
HVY91_RS05750	COG1609	Transcriptional regulator
HVY91_RS05755	COG2311	Membrane
HVY91_RS05770	COG4771	TonB-dependent receptor
HVY91_RS05775	COG0833	amino acid
HVY91_RS05780	COG0583	DNA-binding transcription factor activity
HVY91_RS05785	COG2855	membrane
HVY91_RS05795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVY91_RS05795	COG1522	sequence-specific DNA binding
HVY91_RS05810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HVY91_RS05815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HVY91_RS05820	COG2313	pseudouridylate synthase activity
HVY91_RS05825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVY91_RS05830	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVY91_RS05830	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HVY91_RS05830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVY91_RS05835	COG1105	Belongs to the carbohydrate kinase PfkB family
HVY91_RS05840	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVY91_RS05840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVY91_RS05860	COG0246	Mannitol dehydrogenase
HVY91_RS05865	COG0523	cobalamin synthesis protein
HVY91_RS05870	COG0671	phosphoesterase, PA-phosphatase related
HVY91_RS05875	COG0791	NLP P60 protein
HVY91_RS05880	COG2200	EAL domain
HVY91_RS05885	COG4166	transmembrane transport
HVY91_RS05890	COG4174	ABC transporter (Permease)
HVY91_RS05895	COG4239	(ABC) transporter, permease
HVY91_RS05900	COG4172	Belongs to the ABC transporter superfamily
HVY91_RS05910	COG2814	Major facilitator Superfamily
HVY91_RS05915	COG1187	pseudouridine synthase activity
HVY91_RS05920	COG1061	Type III restriction enzyme res subunit
HVY91_RS05930	COG0596	Alpha beta hydrolase
HVY91_RS05945	COG3083	sulfuric ester hydrolase activity
HVY91_RS05965	COG2197	response regulator
HVY91_RS05970	COG3088	subunit of a heme lyase
HVY91_RS05970	COG4235	cytochrome complex assembly
HVY91_RS05975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HVY91_RS05980	COG1138	Cytochrome C-type biogenesis protein
HVY91_RS05990	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HVY91_RS05995	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HVY91_RS06000	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HVY91_RS06005	COG4133	protoheme IX ABC transporter activity
HVY91_RS06010	COG3005	denitrification pathway
HVY91_RS06015	COG3043	anaerobic respiration
HVY91_RS06020	COG0348	domain, Protein
HVY91_RS06025	COG0437	4 iron, 4 sulfur cluster binding
HVY91_RS06035	COG3062	negative regulation of establishment of protein localization
HVY91_RS06040	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVY91_RS06040	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVY91_RS06050	COG0668	transmembrane transport
HVY91_RS06065	COG4774	siderophore transport
HVY91_RS06075	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HVY91_RS06085	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HVY91_RS06090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HVY91_RS06095	COG1199	ATP-dependent helicase activity
HVY91_RS06100	COG0513	Belongs to the DEAD box helicase family
HVY91_RS06105	COG1309	transcriptional regulator
HVY91_RS06115	COG1131	(ABC) transporter
HVY91_RS06120	COG0842	Transport permease protein
HVY91_RS06125	COG0842	Transport permease protein
HVY91_RS06135	COG3568	Endonuclease Exonuclease Phosphatase
HVY91_RS06140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HVY91_RS06145	COG0392	lysyltransferase activity
HVY91_RS06150	COG0670	Belongs to the BI1 family
HVY91_RS06155	COG2194	sulfuric ester hydrolase activity
HVY91_RS06160	COG0670	Belongs to the BI1 family
HVY91_RS06165	COG0314	molybdopterin synthase activity
HVY91_RS06170	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HVY91_RS06180	COG0521	Mo-molybdopterin cofactor biosynthetic process
HVY91_RS06190	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HVY91_RS06200	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HVY91_RS06205	COG2226	methyltransferase
HVY91_RS06220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HVY91_RS06225	COG1881	PFAM PEBP family protein
HVY91_RS06230	COG4677	pectinesterase activity
HVY91_RS06240	COG0561	phosphatase activity
HVY91_RS06250	COG4149	molybdate abc transporter
HVY91_RS06255	COG0725	ABC transporter, periplasmic molybdate-binding protein
HVY91_RS06265	COG3585	molybdate ion transport
HVY91_RS06265	COG2005	Transcriptional regulator
HVY91_RS06270	COG1119	ATPase activity
HVY91_RS06275	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HVY91_RS06280	COG1085	galactose-1-phosphate uridylyltransferase
HVY91_RS06290	COG2017	converts alpha-aldose to the beta-anomer
HVY91_RS06300	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HVY91_RS06310	COG1230	cation diffusion facilitator family transporter
HVY91_RS06315	COG3201	nicotinamide mononucleotide transporter
HVY91_RS06360	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HVY91_RS06365	COG2885	chlorophyll binding
HVY91_RS06375	COG3064	Membrane
HVY91_RS06380	COG0848	biopolymer transport protein
HVY91_RS06385	COG0811	peptide transport
HVY91_RS06390	COG0824	Thioesterase
HVY91_RS06395	COG3790	cyd operon protein YbgE
HVY91_RS06400	COG4890	Cyd operon protein YbgT
HVY91_RS06405	COG1294	oxidase, subunit
HVY91_RS06410	COG1271	oxidase subunit
HVY91_RS06415	COG0383	alpha-mannosidase activity
HVY91_RS06420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVY91_RS06420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVY91_RS06420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVY91_RS06425	COG2188	Transcriptional regulator
HVY91_RS06430	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HVY91_RS06440	COG4865	methylaspartate mutase activity
HVY91_RS06445	COG3799	methylaspartate ammonia-lyase activity
HVY91_RS06460	COG1301	dicarboxylic acid transport
HVY91_RS06465	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HVY91_RS06465	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HVY91_RS06470	COG0583	DNA-binding transcription factor activity
HVY91_RS06475	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HVY91_RS06485	COG0508	dehydrogenase complex catalyzes the overall conversion of
HVY91_RS06490	COG0567	Dehydrogenase, E1 component
HVY91_RS06495	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HVY91_RS06500	COG1053	succinate dehydrogenase
HVY91_RS06505	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HVY91_RS06510	COG2009	succinate dehydrogenase
HVY91_RS06515	COG0372	Belongs to the citrate synthase family
HVY91_RS06520	COG3539	Fimbrial protein
HVY91_RS06525	COG3188	usher protein
HVY91_RS06530	COG3121	Chaperone
HVY91_RS06535	COG3539	Fimbrial protein
HVY91_RS06540	COG3180	Ammonia monooxygenase
HVY91_RS06565	COG1984	allophanate hydrolase subunit 2
HVY91_RS06570	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HVY91_RS06575	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HVY91_RS06585	COG0415	Belongs to the DNA photolyase family
HVY91_RS06590	COG3272	Protein of unknown function (DUF1722)
HVY91_RS06645	COG2205	protein histidine kinase activity
HVY91_RS06650	COG0745	RESPONSE REGULATOR receiver
HVY91_RS06655	COG1982	Orn Lys Arg decarboxylase major
HVY91_RS06660	COG0531	amino acid
HVY91_RS06665	COG0033	Phosphoglucomutase
HVY91_RS06670	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HVY91_RS06675	COG0596	Alpha beta hydrolase
HVY91_RS06685	COG0716	FMN binding
HVY91_RS06695	COG0735	belongs to the Fur family
HVY91_RS06715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVY91_RS06715	COG1263	PTS System
HVY91_RS06715	COG2190	(PTS) system
HVY91_RS06725	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HVY91_RS06730	COG1846	Transcriptional regulator
HVY91_RS06730	COG1940	carbohydrate kinase activity
HVY91_RS06735	COG0647	UMP catabolic process
HVY91_RS06740	COG0367	asparagine synthase
HVY91_RS06790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HVY91_RS06800	COG1702	phosphate starvation-inducible protein PhoH
HVY91_RS06810	COG4535	Mg2 and Co2 transporter CorC
HVY91_RS06815	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HVY91_RS06825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVY91_RS06830	COG0765	amino acid transport
HVY91_RS06835	COG0765	amino acid transport
HVY91_RS06840	COG1126	abc transporter atp-binding protein
HVY91_RS06850	COG0443	Heat shock 70 kDa protein
HVY91_RS06855	COG2214	Heat shock protein DnaJ domain protein
HVY91_RS06865	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HVY91_RS06870	COG2214	Heat shock protein DnaJ domain protein
HVY91_RS06880	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HVY91_RS06885	COG2888	peptidyl-tyrosine sulfation
HVY91_RS06900	COG1466	dna polymerase III delta subunit
HVY91_RS06910	COG0799	negative regulation of ribosome biogenesis
HVY91_RS06920	COG0768	penicillin binding
HVY91_RS06925	COG0772	Belongs to the SEDS family
HVY91_RS06930	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HVY91_RS06935	COG1686	Belongs to the peptidase S11 family
HVY91_RS06960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HVY91_RS06980	COG3069	C4-dicarboxylate transmembrane transporter activity
HVY91_RS06985	COG3719	Belongs to the RNase T2 family
HVY91_RS06990	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HVY91_RS06995	COG0589	response to stress
HVY91_RS07000	COG3634	alkyl hydroperoxide reductase activity
HVY91_RS07005	COG0450	alkyl hydroperoxide reductase
HVY91_RS07010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HVY91_RS07015	COG0583	DNA-binding transcription factor activity
HVY91_RS07020	COG3969	phosphoadenosine phosphosulfate
HVY91_RS07025	COG1475	DNA binding
HVY91_RS07030	COG0436	Aminotransferase
HVY91_RS07035	COG0371	Dehydrogenase
HVY91_RS07040	COG2879	small protein
HVY91_RS07045	COG1966	Carbon starvation protein
HVY91_RS07055	COG2050	protein possibly involved in aromatic compounds catabolism
HVY91_RS07060	COG1028	Short-chain dehydrogenase reductase Sdr
HVY91_RS07065	COG3433	isochorismatase activity
HVY91_RS07065	COG1535	isochorismatase
HVY91_RS07070	COG1021	2,3-dihydroxybenzoate-AMP ligase
HVY91_RS07075	COG1169	isochorismate synthase
HVY91_RS07080	COG4592	Periplasmic binding protein
HVY91_RS07090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HVY91_RS07095	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HVY91_RS07100	COG1120	ATPase activity
HVY91_RS07105	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HVY91_RS07110	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HVY91_RS07110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HVY91_RS07115	COG3251	PFAM MbtH domain protein
HVY91_RS07120	COG2382	esterase
HVY91_RS07125	COG4771	TonB-dependent receptor
HVY91_RS07130	COG2977	Belongs to the P-Pant transferase superfamily
HVY91_RS07160	COG2315	Protein conserved in bacteria
HVY91_RS07165	COG0778	Nitroreductase
HVY91_RS07170	COG0668	transmembrane transport
HVY91_RS07175	COG1113	amino acid transport
HVY91_RS07180	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HVY91_RS07185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVY91_RS07190	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVY91_RS07195	COG1538	Outer membrane efflux protein
HVY91_RS07200	COG0745	RESPONSE REGULATOR receiver
HVY91_RS07205	COG5002	protein histidine kinase activity
HVY91_RS07240	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HVY91_RS07250	COG2832	Protein of unknown function (DUF454)
HVY91_RS07255	COG3923	Primosomal replication protein n
HVY91_RS07265	COG3264	Mechanosensitive ion channel
HVY91_RS07265	COG1196	nuclear chromosome segregation
HVY91_RS07270	COG1309	transcriptional regulator
HVY91_RS07275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVY91_RS07280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HVY91_RS07300	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HVY91_RS07305	COG5507	3-demethylubiquinone-9 3-methyltransferase
HVY91_RS07315	COG3695	enzyme binding
HVY91_RS07320	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HVY91_RS07325	COG1946	Acyl-CoA thioesterase
HVY91_RS07330	COG0004	ammonium transporteR
HVY91_RS07335	COG0347	Belongs to the P(II) protein family
HVY91_RS07340	COG1132	(ABC) transporter
HVY91_RS07345	COG1132	(ABC) transporter
HVY91_RS07350	COG1522	sequence-specific DNA binding
HVY91_RS07360	COG4533	DNA binding
HVY91_RS07370	COG0824	Thioesterase
HVY91_RS07375	COG1555	photosystem II stabilization
HVY91_RS07380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HVY91_RS07385	COG0776	regulation of translation
HVY91_RS07390	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HVY91_RS07410	COG0271	Belongs to the BolA IbaG family
HVY91_RS07415	COG3056	Lipoprotein
HVY91_RS07420	COG2223	nitrite transmembrane transporter activity
HVY91_RS07425	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HVY91_RS07430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HVY91_RS07435	COG1845	cytochrome c oxidase, subunit III
HVY91_RS07440	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HVY91_RS07460	COG1414	Transcriptional regulator
HVY91_RS07465	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HVY91_RS07495	COG2814	Major facilitator Superfamily
HVY91_RS07505	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HVY91_RS07510	COG0693	protein deglycase activity
HVY91_RS07525	COG0142	geranyltranstransferase activity
HVY91_RS07535	COG0667	Aldo Keto reductase
HVY91_RS07540	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HVY91_RS07560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HVY91_RS07560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HVY91_RS07570	COG4238	major outer membrane lipoprotein
HVY91_RS07575	COG3248	Nucleoside-binding outer membrane protein
HVY91_RS07585	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HVY91_RS07590	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HVY91_RS07595	COG1862	Preprotein translocase
HVY91_RS07615	COG0366	Alpha amylase catalytic
HVY91_RS07620	COG1113	amino acid transport
HVY91_RS07625	COG1114	Component of the transport system for branched-chain amino acids
HVY91_RS07630	COG5002	protein histidine kinase activity
HVY91_RS07640	COG0420	3'-5' exonuclease activity
HVY91_RS07645	COG0419	ATPase involved in DNA repair
HVY91_RS07650	COG1940	carbohydrate kinase activity
HVY91_RS07665	COG4126	flavin adenine dinucleotide binding
HVY91_RS07685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HVY91_RS07690	COG3706	GGDEF domain
HVY91_RS07710	COG1181	Belongs to the D-alanine--D-alanine ligase family
HVY91_RS07730	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HVY91_RS07735	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HVY91_RS07740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HVY91_RS07750	COG0113	porphobilinogen synthase activity
HVY91_RS07755	COG2175	clavaminate synthase activity
HVY91_RS07760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HVY91_RS07770	COG4521	taurine ABC transporter
HVY91_RS07775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HVY91_RS07785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HVY91_RS07790	COG2079	MmgE PrpD family protein
HVY91_RS07795	COG0372	Belongs to the citrate synthase family
HVY91_RS07800	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HVY91_RS07805	COG3829	transcription factor binding
HVY91_RS07815	COG1280	lysine exporter protein (LysE YggA)
HVY91_RS07820	COG3706	GGDEF domain
HVY91_RS07825	COG2186	Transcriptional regulator
HVY91_RS07830	COG1063	alcohol dehydrogenase
HVY91_RS07835	COG2271	Major facilitator Superfamily
HVY91_RS07840	COG2200	EAL domain
HVY91_RS07850	COG2771	luxR family
HVY91_RS07850	COG2200	EAL domain
HVY91_RS07855	COG0454	-acetyltransferase
HVY91_RS07860	COG0656	L-ascorbic acid biosynthetic process
HVY91_RS07865	COG0667	Aldo Keto reductase
HVY91_RS07890	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HVY91_RS07895	COG5301	cellulose 1,4-beta-cellobiosidase activity
HVY91_RS07930	COG1196	nuclear chromosome segregation
HVY91_RS07980	COG1030	water channel activity
HVY91_RS08000	COG4220	transposase activity
HVY91_RS08010	COG5562	phage envelope protein
HVY91_RS08025	COG3772	lysozyme
HVY91_RS08035	COG2207	Transcriptional regulator
HVY91_RS08040	COG3272	Protein of unknown function (DUF1722)
HVY91_RS08095	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HVY91_RS08190	COG0582	viral genome integration into host DNA
HVY91_RS08195	COG1196	nuclear chromosome segregation
HVY91_RS08210	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HVY91_RS08220	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HVY91_RS08235	COG3778	Protein conserved in bacteria
HVY91_RS08240	COG3299	homolog of phage Mu protein gp47
HVY91_RS08260	COG4228	DNA circulation
HVY91_RS08280	COG4386	tail sheath protein
HVY91_RS08325	COG4695	Portal protein
HVY91_RS08335	COG1802	Transcriptional regulator
HVY91_RS08335	COG4626	Terminase
HVY91_RS08380	COG1403	HNH endonuclease
HVY91_RS08390	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HVY91_RS08400	COG4725	Belongs to the MT-A70-like family
HVY91_RS08410	COG1846	Transcriptional regulator
HVY91_RS08455	COG5532	Uncharacterized conserved protein (DUF2303)
HVY91_RS08460	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HVY91_RS08475	COG0582	viral genome integration into host DNA
HVY91_RS08495	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HVY91_RS08515	COG2195	Cleaves the N-terminal amino acid of tripeptides
HVY91_RS08530	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HVY91_RS08540	COG0454	-acetyltransferase
HVY91_RS08550	COG2161	toxin-antitoxin pair type II binding
HVY91_RS08570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HVY91_RS08575	COG1074	ATP-dependent DNA helicase activity
HVY91_RS08580	COG1025	Belongs to the peptidase M16 family
HVY91_RS08585	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HVY91_RS08590	COG4967	type IV pilus modification protein PilV
HVY91_RS08600	COG4795	General secretion pathway protein
HVY91_RS08605	COG2165	general secretion pathway protein
HVY91_RS08635	COG0861	Integral membrane protein TerC family
HVY91_RS08645	COG0667	Aldo Keto reductase
HVY91_RS08670	COG1609	Transcriptional regulator
HVY91_RS08680	COG0583	DNA-binding transcription factor activity
HVY91_RS08685	COG0183	Belongs to the thiolase family
HVY91_RS08690	COG0814	amino acid
HVY91_RS08695	COG2771	luxR family
HVY91_RS08700	COG3710	Transcriptional regulator
HVY91_RS08710	COG1215	transferase activity, transferring glycosyl groups
HVY91_RS08715	COG4783	chaperone-mediated protein folding
HVY91_RS08725	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HVY91_RS08730	COG0402	S-adenosylhomocysteine deaminase activity
HVY91_RS08750	COG1470	cell adhesion involved in biofilm formation
HVY91_RS08750	COG1388	LysM domain
HVY91_RS08770	COG4942	peptidase
HVY91_RS08775	COG0235	Class ii aldolase
HVY91_RS08790	COG1126	abc transporter atp-binding protein
HVY91_RS08795	COG0583	DNA-binding transcription factor activity
HVY91_RS08800	COG2072	flavoprotein involved in K transport
HVY91_RS08815	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HVY91_RS08820	COG0076	glutamate decarboxylase activity
HVY91_RS08825	COG2066	Belongs to the glutaminase family
HVY91_RS08830	COG2080	2 iron, 2 sulfur cluster binding
HVY91_RS08835	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HVY91_RS08840	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HVY91_RS08845	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HVY91_RS08860	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HVY91_RS08870	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HVY91_RS08875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HVY91_RS08880	COG4974	Belongs to the 'phage' integrase family
HVY91_RS08885	COG0716	FMN binding
HVY91_RS08895	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HVY91_RS08905	COG1272	protein, Hemolysin III
HVY91_RS08915	COG2723	6-phospho-beta-galactosidase activity
HVY91_RS08945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HVY91_RS08950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HVY91_RS08955	COG0006	proline dipeptidase activity
HVY91_RS08975	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HVY91_RS08985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HVY91_RS09000	COG2968	Membrane
HVY91_RS09005	COG1279	arginine transmembrane transporter activity
HVY91_RS09010	COG0668	transmembrane transport
HVY91_RS09015	COG0191	fructose-bisphosphate aldolase activity
HVY91_RS09030	COG1072	(Pantothenic acid kinase))
HVY91_RS09040	COG1494	fructose-1,6-bisphosphatase
HVY91_RS09045	COG1063	alcohol dehydrogenase
HVY91_RS09050	COG2213	PTS system mannitol-specific
HVY91_RS09055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVY91_RS09060	COG0330	HflC and HflK could
HVY91_RS09065	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HVY91_RS09070	COG0501	Belongs to the peptidase M48B family
HVY91_RS09080	COG4948	Mandelate Racemase Muconate Lactonizing
HVY91_RS09090	COG1028	Short-chain dehydrogenase reductase Sdr
HVY91_RS09095	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HVY91_RS09100	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HVY91_RS09105	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HVY91_RS09110	COG1166	arginine decarboxylase activity
HVY91_RS09135	COG2814	Major facilitator Superfamily
HVY91_RS09145	COG2356	endonuclease I
HVY91_RS09150	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HVY91_RS09155	COG0189	ligase activity
HVY91_RS09170	COG2805	Type II/IV secretion system protein
HVY91_RS09175	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HVY91_RS09180	COG0762	integral membrane protein
HVY91_RS09190	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HVY91_RS09195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HVY91_RS09200	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HVY91_RS09205	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HVY91_RS09220	COG0252	asparaginase activity
HVY91_RS09230	COG3171	Protein conserved in bacteria
HVY91_RS09240	COG1194	a g-specific adenine glycosylase
HVY91_RS09255	COG2211	Major facilitator Superfamily
HVY91_RS09260	COG1982	Orn Lys Arg decarboxylase major
HVY91_RS09265	COG1811	Na channel or pump
HVY91_RS09290	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HVY91_RS09310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HVY91_RS09315	COG1459	type II secretion system
HVY91_RS09320	COG2165	general secretion pathway protein
HVY91_RS09335	COG4795	General secretion pathway protein
HVY91_RS09350	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HVY91_RS09380	COG0754	glutathionylspermidine amidase activity
HVY91_RS09385	COG2207	Transcriptional regulator
HVY91_RS09390	COG0625	glutathione transferase activity
HVY91_RS09395	COG0298	carbon dioxide binding
HVY91_RS09405	COG1773	rubredoxin
HVY91_RS09410	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HVY91_RS09415	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HVY91_RS09420	COG5557	Pfam Polysulphide reductase, NrfD
HVY91_RS09425	COG0437	4 iron, 4 sulfur cluster binding
HVY91_RS09430	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HVY91_RS09445	COG0667	Aldo Keto reductase
HVY91_RS09455	COG1028	Short-chain dehydrogenase reductase Sdr
HVY91_RS09460	COG0848	biopolymer transport protein
HVY91_RS09465	COG0811	peptide transport
HVY91_RS09470	COG0626	cystathionine gamma-synthase activity
HVY91_RS09475	COG0586	Pfam SNARE associated Golgi protein
HVY91_RS09480	COG2207	Transcriptional regulator
HVY91_RS09485	COG1979	alcohol dehydrogenase
HVY91_RS09490	COG0656	L-ascorbic acid biosynthetic process
HVY91_RS09495	COG0471	metal ion transport
HVY91_RS09500	COG4238	major outer membrane lipoprotein
HVY91_RS09515	COG1032	radical SAM domain protein
HVY91_RS09520	COG2186	Transcriptional regulator
HVY91_RS09525	COG0246	Mannitol dehydrogenase
HVY91_RS09530	COG1063	alcohol dehydrogenase
HVY91_RS09535	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HVY91_RS09560	COG0204	Acyl-transferase
HVY91_RS09565	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HVY91_RS09570	COG3111	PFAM Bacterial OB fold (BOF) protein
HVY91_RS09575	COG0745	RESPONSE REGULATOR receiver
HVY91_RS09580	COG0642	Histidine kinase
HVY91_RS09585	COG2249	NAD(P)H dehydrogenase (quinone) activity
HVY91_RS09590	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HVY91_RS09595	COG0187	DNA topoisomerase II activity
HVY91_RS09600	COG3150	esterase
HVY91_RS09605	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HVY91_RS09610	COG3151	Protein conserved in bacteria
HVY91_RS09615	COG0494	nUDIX hydrolase
HVY91_RS09620	COG1538	Outer membrane efflux protein
HVY91_RS09630	COG0754	glutathionylspermidine amidase activity
HVY91_RS09650	COG3384	dioxygenase
HVY91_RS09665	COG3539	Fimbrial protein
HVY91_RS09670	COG3188	usher protein
HVY91_RS09675	COG3121	Chaperone
HVY91_RS09680	COG3539	Fimbrial protein
HVY91_RS09700	COG1585	Membrane protein implicated in regulation of membrane protease activity
HVY91_RS09705	COG2268	Band 7 protein
HVY91_RS09735	COG3025	triphosphatase activity
HVY91_RS09740	COG4991	sh3 domain protein
HVY91_RS09755	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HVY91_RS09770	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HVY91_RS09775	COG0358	DNA primase activity
HVY91_RS09780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HVY91_RS09840	COG3118	belongs to the thioredoxin family
HVY91_RS09850	COG2375	cellular response to nickel ion
HVY91_RS09855	COG1695	Transcriptional regulator
HVY91_RS09860	COG0840	transmembrane signaling receptor activity
HVY91_RS09870	COG0477	Major facilitator Superfamily
HVY91_RS09875	COG3501	Rhs element vgr protein
HVY91_RS09880	COG2186	Transcriptional regulator
HVY91_RS09885	COG0246	Mannitol dehydrogenase
HVY91_RS09895	COG3065	identical protein binding
HVY91_RS09900	COG2197	response regulator
HVY91_RS09905	COG1285	pathogenesis
HVY91_RS09920	COG3247	response to pH
HVY91_RS09925	COG2771	luxR family
HVY91_RS09930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVY91_RS09935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HVY91_RS09940	COG2207	Transcriptional regulator
HVY91_RS09975	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HVY91_RS09980	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
HVY91_RS09985	COG1924	4 iron, 4 sulfur cluster binding
HVY91_RS09995	COG0446	pyridine nucleotide-disulphide oxidoreductase
HVY91_RS09995	COG1902	pentaerythritol trinitrate reductase activity
HVY91_RS10000	COG0840	transmembrane signaling receptor activity
HVY91_RS10010	COG4145	pantothenate transmembrane transporter activity
HVY91_RS10020	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HVY91_RS10030	COG1846	Transcriptional regulator
HVY91_RS10035	COG0179	Fumarylacetoacetate (FAA) hydrolase
HVY91_RS10040	COG1012	belongs to the aldehyde dehydrogenase family
HVY91_RS10045	COG3384	dioxygenase
HVY91_RS10055	COG3971	2-oxopent-4-enoate hydratase activity
HVY91_RS10075	COG2368	4-hydroxyphenylacetate
HVY91_RS10080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HVY91_RS10085	COG1966	Carbon starvation protein
HVY91_RS10090	COG2879	small protein
HVY91_RS10095	COG0523	cobalamin synthesis protein
HVY91_RS10100	COG0514	ATP-dependent DNA helicase (RecQ)
HVY91_RS10105	COG3586	endonuclease activity
HVY91_RS10110	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HVY91_RS10130	COG5457	Domain of unknown function (DUF1127)
HVY91_RS10140	COG2814	Major facilitator Superfamily
HVY91_RS10145	COG2733	membrane
HVY91_RS10235	COG0582	viral genome integration into host DNA
HVY91_RS10245	COG1064	alcohol dehydrogenase
HVY91_RS10250	COG0433	COG0433 Predicted ATPase
HVY91_RS10255	COG0701	Predicted permease
HVY91_RS10260	COG0702	epimerase
HVY91_RS10265	COG0693	protein deglycase activity
HVY91_RS10280	COG3153	acetyltransferase
HVY91_RS10285	COG3154	lipid carrier protein
HVY91_RS10290	COG0826	peptidase U32
HVY91_RS10295	COG0826	peptidase U32
HVY91_RS10300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HVY91_RS10305	COG3034	peptidoglycan biosynthetic process
HVY91_RS10315	COG0814	amino acid
HVY91_RS10320	COG0513	Belongs to the DEAD box helicase family
HVY91_RS10360	COG0195	Participates in both transcription termination and antitermination
HVY91_RS10380	COG2194	sulfuric ester hydrolase activity
HVY91_RS10390	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HVY91_RS10400	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HVY91_RS10405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HVY91_RS10415	COG1534	Rna-binding protein
HVY91_RS10420	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HVY91_RS10425	COG2027	D-alanyl-D-alanine carboxypeptidase
HVY91_RS10435	COG0697	spore germination
HVY91_RS10450	COG0142	geranyltranstransferase activity
HVY91_RS10455	COG3423	Transcriptional regulator
HVY91_RS10465	COG5007	Belongs to the BolA IbaG family
HVY91_RS10470	COG3113	response to antibiotic
HVY91_RS10475	COG2854	intermembrane phospholipid transfer
HVY91_RS10480	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HVY91_RS10485	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HVY91_RS10490	COG1127	ABC transporter
HVY91_RS10495	COG0530	calcium, potassium:sodium antiporter activity
HVY91_RS10500	COG0517	IMP dehydrogenase activity
HVY91_RS10500	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HVY91_RS10505	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HVY91_RS10510	COG3117	lipopolysaccharide transmembrane transporter activity
HVY91_RS10515	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HVY91_RS10520	COG1137	ATPase activity
HVY91_RS10525	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HVY91_RS10530	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HVY91_RS10545	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVY91_RS10550	COG0515	serine threonine protein kinase
HVY91_RS10560	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HVY91_RS10565	COG0784	Response regulator, receiver
HVY91_RS10565	COG5002	protein histidine kinase activity
HVY91_RS10565	COG2198	Histidine kinase
HVY91_RS10570	COG1242	4 iron, 4 sulfur cluster binding
HVY91_RS10575	COG0069	glutamate synthase activity
HVY91_RS10575	COG0070	glutamate synthase
HVY91_RS10575	COG0067	glutamate synthase
HVY91_RS10580	COG0493	'glutamate synthase
HVY91_RS10585	COG4804	nuclease activity
HVY91_RS10590	COG2731	YhcH YjgK YiaL family protein
HVY91_RS10620	COG2969	positive regulation of protein catabolic process
HVY91_RS10625	COG0625	glutathione transferase activity
HVY91_RS10640	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HVY91_RS10645	COG3105	Protein conserved in bacteria
HVY91_RS10650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HVY91_RS10655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HVY91_RS10665	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HVY91_RS10670	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HVY91_RS10675	COG0471	metal ion transport
HVY91_RS10685	COG1802	Transcriptional regulator
HVY91_RS10705	COG2732	(Barnase) inhibitor
HVY91_RS10725	COG0583	DNA-binding transcription factor activity
HVY91_RS10730	COG0312	modulator of DNA gyrase
HVY91_RS10735	COG3164	Protein of unknown function
HVY91_RS10740	COG1530	ribonuclease E activity
HVY91_RS10750	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HVY91_RS10755	COG1792	Involved in formation and maintenance of cell shape
HVY91_RS10760	COG1077	Cell shape determining protein MreB Mrl
HVY91_RS10765	COG2199	diguanylate cyclase activity
HVY91_RS10765	COG2200	EAL domain
HVY91_RS10770	COG0604	alcohol dehydrogenase
HVY91_RS10785	COG0511	ligase activity, forming carbon-carbon bonds
HVY91_RS10790	COG0439	Biotin carboxylase
HVY91_RS10795	COG3924	membrane
HVY91_RS10800	COG4145	pantothenate transmembrane transporter activity
HVY91_RS10810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HVY91_RS10820	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HVY91_RS10830	COG1309	transcriptional regulator
HVY91_RS10835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVY91_RS10840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HVY91_RS10850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVY91_RS10855	COG4597	amino acid ABC transporter
HVY91_RS10860	COG0765	amino acid transport
HVY91_RS10865	COG1126	abc transporter atp-binding protein
HVY91_RS10905	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HVY91_RS10925	COG0551	DNA topoisomerase type I activity
HVY91_RS10935	COG0758	DNA mediated transformation
HVY91_RS10955	COG0569	domain protein
HVY91_RS10965	COG3036	rescue of stalled ribosome
HVY91_RS10970	COG0789	Transcriptional regulator
HVY91_RS11010	COG0201	protein transport
HVY91_RS11100	COG0089	rRNA binding
HVY91_RS11115	COG0051	transcription antitermination factor activity, RNA binding
HVY91_RS11170	COG2964	Protein conserved in bacteria
HVY91_RS11175	COG0545	Peptidyl-prolyl cis-trans isomerase
HVY91_RS11185	COG1047	Peptidyl-prolyl cis-trans
HVY91_RS11190	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HVY91_RS11205	COG0488	(ABC) transporter
HVY91_RS11210	COG0429	hydrolase of the alpha beta-hydrolase fold
HVY91_RS11220	COG3954	Phosphoribulokinase
HVY91_RS11225	COG1765	OsmC-like protein
HVY91_RS11230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HVY91_RS11235	COG1289	transmembrane transporter activity
HVY91_RS11240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HVY91_RS11245	COG0512	Glutamine amidotransferase of anthranilate synthase
HVY91_RS11250	COG2184	nucleotidyltransferase activity
HVY91_RS11265	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HVY91_RS11270	COG2146	nitrite reductase [NAD(P)H] activity
HVY91_RS11275	COG2116	formate transmembrane transporter activity
HVY91_RS11290	COG0626	cystathionine gamma-synthase activity
HVY91_RS11305	COG1735	metal-dependent hydrolase with the TIM-barrel fold
HVY91_RS11310	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HVY91_RS11315	COG3457	Alanine racemase
HVY91_RS11325	COG2188	Transcriptional regulator
HVY91_RS11330	COG0180	Tryptophanyl-tRNA synthetase
HVY91_RS11340	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HVY91_RS11345	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HVY91_RS11350	COG3266	domain, Protein
HVY91_RS11365	COG4796	Type ii and iii secretion system protein
HVY91_RS11380	COG3166	PFAM Fimbrial assembly family protein
HVY91_RS11385	COG4972	Pilus assembly protein
HVY91_RS11390	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HVY91_RS11395	COG0494	nUDIX hydrolase
HVY91_RS11405	COG1011	Hydrolase
HVY91_RS11410	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HVY91_RS11420	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HVY91_RS11440	COG2205	protein histidine kinase activity
HVY91_RS11445	COG0745	RESPONSE REGULATOR receiver
HVY91_RS11450	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HVY91_RS11455	COG2183	response to ionizing radiation
HVY91_RS11460	COG1918	ferrous iron import across plasma membrane
HVY91_RS11465	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HVY91_RS11475	COG5464	transposase or invertase
HVY91_RS11495	COG2610	gluconate transmembrane transporter activity
HVY91_RS11505	COG1640	4-alpha-glucanotransferase
HVY91_RS11510	COG0058	SHG alpha-glucan phosphorylase activity
HVY91_RS11525	COG1690	Belongs to the RtcB family
HVY91_RS11530	COG4650	regulator
HVY91_RS11535	COG1349	DNA-binding transcription factor activity
HVY91_RS11550	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HVY91_RS11565	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HVY91_RS11585	COG3121	Chaperone
HVY91_RS11595	COG3539	Fimbrial protein
HVY91_RS11600	COG3188	usher protein
HVY91_RS11605	COG3121	Chaperone
HVY91_RS11615	COG0058	SHG alpha-glucan phosphorylase activity
HVY91_RS11640	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HVY91_RS11645	COG2095	MarC family integral membrane protein
HVY91_RS11650	COG2610	gluconate transmembrane transporter activity
HVY91_RS11655	COG3265	gluconokinase activity
HVY91_RS11660	COG1609	Transcriptional regulator
HVY91_RS11665	COG1741	Belongs to the pirin family
HVY91_RS11670	COG0673	inositol 2-dehydrogenase activity
HVY91_RS11675	COG1247	-acetyltransferase
HVY91_RS11680	COG0405	Gamma-glutamyltransferase
HVY91_RS11690	COG0584	glycerophosphoryl diester phosphodiesterase
HVY91_RS11705	COG1175	transmembrane transport
HVY91_RS11710	COG1653	transport
HVY91_RS11715	COG0410	ABC transporter
HVY91_RS11720	COG0411	ABC transporter
HVY91_RS11725	COG4177	L-phenylalanine transmembrane transporter activity
HVY91_RS11730	COG0559	Belongs to the binding-protein-dependent transport system permease family
HVY91_RS11735	COG0683	leucine binding
HVY91_RS11740	COG0456	acetyltransferase
HVY91_RS11745	COG0683	leucine binding
HVY91_RS11750	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HVY91_RS11755	COG2177	Part of the ABC transporter FtsEX involved in
HVY91_RS11760	COG2884	Cell division ATP-binding protein ftsE
HVY91_RS11765	COG0552	protein localization to endoplasmic reticulum
HVY91_RS11770	COG0742	ribosomal rna small subunit methyltransferase
HVY91_RS11775	COG3776	membrane
HVY91_RS11785	COG3714	YhhN family
HVY91_RS11805	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HVY91_RS11820	COG0628	permease
HVY91_RS11840	COG0204	Acyl-transferase
HVY91_RS11850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HVY91_RS11870	COG1216	Glycosyl transferase, family 2
HVY91_RS11895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HVY91_RS11905	COG1028	Short-chain dehydrogenase reductase Sdr
HVY91_RS11910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HVY91_RS11915	COG2091	lysine biosynthetic process via aminoadipic acid
HVY91_RS11925	COG0842	Transport permease protein
HVY91_RS11930	COG0842	Transport permease protein
HVY91_RS11930	COG1129	ABC transporter
HVY91_RS11935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVY91_RS11960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVY91_RS11965	COG2081	HI0933 family
HVY91_RS11970	COG0306	phosphate transporter
HVY91_RS11980	COG0589	response to stress
HVY91_RS11985	COG3104	oligopeptide transport
HVY91_RS11995	COG0339	signal peptide processing
HVY91_RS12000	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HVY91_RS12005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HVY91_RS12015	COG0640	Transcriptional regulator
HVY91_RS12020	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HVY91_RS12025	COG1393	Belongs to the ArsC family
HVY91_RS12045	COG2197	response regulator
HVY91_RS12050	COG1295	ribonuclease BN
HVY91_RS12055	COG0477	Major facilitator Superfamily
HVY91_RS12060	COG2982	Protein involved in outer membrane biogenesis
HVY91_RS12065	COG2200	EAL domain
HVY91_RS12070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVY91_RS12120	COG0612	Peptidase, M16
HVY91_RS12130	COG2200	EAL domain
HVY91_RS12130	COG2199	diguanylate cyclase activity
HVY91_RS12135	COG3118	belongs to the thioredoxin family
HVY91_RS12135	COG0457	Tetratricopeptide repeat
HVY91_RS12140	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HVY91_RS12145	COG1215	transferase activity, transferring glycosyl groups
HVY91_RS12150	COG1215	transferase activity, transferring glycosyl groups
HVY91_RS12175	COG2194	sulfuric ester hydrolase activity
HVY91_RS12205	COG0814	amino acid
HVY91_RS12215	COG4608	Belongs to the ABC transporter superfamily
HVY91_RS12220	COG0444	Belongs to the ABC transporter superfamily
HVY91_RS12225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HVY91_RS12230	COG0601	transmembrane transport
HVY91_RS12235	COG0747	negative chemotaxis
HVY91_RS12245	COG2194	sulfuric ester hydrolase activity
HVY91_RS12250	COG2223	nitrite transmembrane transporter activity
HVY91_RS12255	COG5571	outer membrane autotransporter
HVY91_RS12260	COG2818	Glycosylase
HVY91_RS12265	COG0456	acetyltransferase
HVY91_RS12270	COG0243	molybdopterin cofactor binding
HVY91_RS12275	COG2885	chlorophyll binding
HVY91_RS12280	COG1609	Transcriptional regulator
HVY91_RS12290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVY91_RS12310	COG2814	Major facilitator Superfamily
HVY91_RS12315	COG2944	sequence-specific DNA binding
HVY91_RS12320	COG1278	Cold shock
HVY91_RS12350	COG3274	enterobacterial common antigen metabolic process
HVY91_RS12355	COG4682	membrane
HVY91_RS12360	COG1070	Carbohydrate kinase
HVY91_RS12370	COG1609	Transcriptional regulator
HVY91_RS12370	COG2207	Transcriptional regulator
HVY91_RS12375	COG2992	FlgJ-related protein
HVY91_RS12380	COG0366	Alpha amylase catalytic
HVY91_RS12385	COG3977	Valine--pyruvate aminotransferase
HVY91_RS12390	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVY91_RS12395	COG1414	Transcriptional regulator
HVY91_RS12405	COG2731	YhcH YjgK YiaL family protein
HVY91_RS12410	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HVY91_RS12415	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HVY91_RS12420	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HVY91_RS12425	COG1070	Carbohydrate kinase
HVY91_RS12430	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HVY91_RS12435	COG3623	hexulose-6-phosphate isomerase
HVY91_RS12440	COG0235	Class ii aldolase
HVY91_RS12445	COG1012	belongs to the aldehyde dehydrogenase family
HVY91_RS12450	COG1454	alcohol dehydrogenase
HVY91_RS12455	COG3276	selenocysteine insertion sequence binding
HVY91_RS12465	COG0625	glutathione transferase activity
HVY91_RS12470	COG1566	PFAM secretion protein HlyD family protein
HVY91_RS12480	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVY91_RS12480	COG2213	PTS system mannitol-specific
HVY91_RS12490	COG3722	fumarate hydratase activity
HVY91_RS12510	COG5295	Hep Hag repeat protein
HVY91_RS12520	COG2186	Transcriptional regulator
HVY91_RS12530	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HVY91_RS12535	COG1045	serine acetyltransferase
HVY91_RS12550	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HVY91_RS12555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HVY91_RS12565	COG4942	peptidase
HVY91_RS12570	COG2861	carbohydrate metabolic process
HVY91_RS12575	COG1216	Glycosyl transferase, family 2
HVY91_RS12580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HVY91_RS12585	COG3078	GTPase activator activity
HVY91_RS12600	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HVY91_RS12600	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HVY91_RS12605	COG0204	Acyl-transferase
HVY91_RS12610	COG5339	Protein conserved in bacteria
HVY91_RS12615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HVY91_RS12620	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HVY91_RS12625	COG3084	Protein conserved in bacteria
HVY91_RS12630	COG0746	molybdenum cofactor guanylyltransferase activity
HVY91_RS12635	COG1763	Mo-molybdopterin cofactor biosynthetic process
HVY91_RS12665	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
HVY91_RS12670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HVY91_RS12675	COG1739	Uncharacterized protein family UPF0029
HVY91_RS12700	COG0543	2 iron, 2 sulfur cluster binding
HVY91_RS12705	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HVY91_RS12710	COG0250	Participates in transcription elongation, termination and antitermination
HVY91_RS12720	COG0805	protein transport
HVY91_RS12725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HVY91_RS12730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HVY91_RS12740	COG3165	ubiquinone biosynthetic process from chorismate
HVY91_RS12750	COG1322	Protein conserved in bacteria
HVY91_RS12755	COG1414	Transcriptional regulator
HVY91_RS12760	COG3734	2-keto-3-deoxy-galactonokinase
HVY91_RS12765	COG0800	Aldolase
HVY91_RS12785	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HVY91_RS12790	COG0412	Dienelactone hydrolase
HVY91_RS12800	COG0583	DNA-binding transcription factor activity
HVY91_RS12805	COG0697	spore germination
HVY91_RS12810	COG0561	phosphatase activity
HVY91_RS12815	COG2267	carboxylic ester hydrolase activity
HVY91_RS12820	COG1280	lysine exporter protein (LysE YggA)
HVY91_RS12825	COG1280	lysine exporter protein (LysE YggA)
HVY91_RS12830	COG0514	ATP-dependent DNA helicase (RecQ)
HVY91_RS12835	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
HVY91_RS12840	COG2050	protein possibly involved in aromatic compounds catabolism
HVY91_RS12845	COG2962	Rard protein
HVY91_RS12855	COG0598	Magnesium transport protein CorA
HVY91_RS12860	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
HVY91_RS12865	COG0210	DNA helicase
HVY91_RS12870	COG1011	Hydrolase
HVY91_RS12880	COG3159	Protein conserved in bacteria
HVY91_RS12890	COG5567	small periplasmic lipoprotein
HVY91_RS12910	COG3072	Adenylate cyclase
HVY91_RS12925	COG2959	enzyme of heme biosynthesis
HVY91_RS12930	COG3071	HemY protein
HVY91_RS12935	COG3119	arylsulfatase activity
HVY91_RS12940	COG0641	radical SAM
HVY91_RS12965	COG1113	amino acid transport
HVY91_RS12985	COG2244	polysaccharide biosynthetic process
HVY91_RS12990	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HVY91_RS12995	COG0456	acetyltransferase
HVY91_RS13000	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HVY91_RS13005	COG1088	dTDP-glucose 4,6-dehydratase activity
HVY91_RS13010	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HVY91_RS13015	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HVY91_RS13020	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
HVY91_RS13025	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HVY91_RS13030	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HVY91_RS13040	COG3118	belongs to the thioredoxin family
HVY91_RS13055	COG0210	DNA helicase
HVY91_RS13060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HVY91_RS13070	COG0583	DNA-binding transcription factor activity
HVY91_RS13075	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HVY91_RS13085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HVY91_RS13090	COG3978	acetolactate synthase activity
HVY91_RS13115	COG3085	chromosome segregation
HVY91_RS13155	COG2186	Transcriptional regulator
HVY91_RS13160	COG1609	Transcriptional regulator
HVY91_RS13165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVY91_RS13170	COG1879	ABC-type sugar transport system periplasmic component
HVY91_RS13175	COG1172	Belongs to the binding-protein-dependent transport system permease family
HVY91_RS13180	COG1129	ABC transporter
HVY91_RS13210	COG1522	sequence-specific DNA binding
HVY91_RS13215	COG0716	FMN binding
HVY91_RS13230	COG3312	ion transport
HVY91_RS13290	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HVY91_RS13295	COG0573	inorganic phosphate transmembrane transporter activity
HVY91_RS13300	COG0581	inorganic phosphate transmembrane transporter activity
HVY91_RS13305	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HVY91_RS13310	COG0704	Plays a role in the regulation of phosphate uptake
HVY91_RS13315	COG3711	transcriptional antiterminator
HVY91_RS13320	COG1263	PTS System
HVY91_RS13320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVY91_RS13320	COG2190	(PTS) system
HVY91_RS13325	COG2723	6-phospho-beta-galactosidase activity
HVY91_RS13335	COG2382	esterase
HVY91_RS13340	COG0363	glucosamine-6-phosphate deaminase activity
HVY91_RS13345	COG3196	Protein conserved in bacteria
HVY91_RS13355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HVY91_RS13360	COG2252	PERMEase
HVY91_RS13370	COG0431	NADPH-dependent FMN reductase
HVY91_RS13375	COG2091	lysine biosynthetic process via aminoadipic acid
HVY91_RS13390	COG0814	amino acid
HVY91_RS13440	COG0592	DNA-directed DNA polymerase activity
HVY91_RS13450	COG0187	DNA topoisomerase II activity
HVY91_RS13455	COG3753	Protein conserved in bacteria
HVY91_RS13460	COG0561	phosphatase activity
HVY91_RS13470	COG2186	Transcriptional regulator
HVY91_RS13475	COG3734	2-keto-3-deoxy-galactonokinase
HVY91_RS13480	COG0800	Aldolase
HVY91_RS13490	COG2271	Major facilitator Superfamily
HVY91_RS13500	COG0823	Involved in the tonB-independent uptake of proteins
HVY91_RS13505	COG5645	(Lipo)protein
HVY91_RS13525	COG2188	Transcriptional regulator
HVY91_RS13540	COG2207	Transcriptional regulator
HVY91_RS13545	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HVY91_RS13550	COG3119	arylsulfatase activity
HVY91_RS13560	COG2149	membrane
HVY91_RS13570	COG0641	radical SAM
HVY91_RS13575	COG2814	Major facilitator Superfamily
HVY91_RS13590	COG0028	Belongs to the TPP enzyme family
HVY91_RS13595	COG0440	acetolactate synthase activity
HVY91_RS13600	COG2197	response regulator
HVY91_RS13605	COG3851	Histidine kinase
HVY91_RS13610	COG2271	Major facilitator Superfamily
HVY91_RS13615	COG2271	Major facilitator Superfamily
HVY91_RS13635	COG1447	Phosphotransferase system cellobiose-specific component IIA
HVY91_RS13640	COG2723	6-phospho-beta-galactosidase activity
HVY91_RS13645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HVY91_RS13655	COG1609	Transcriptional regulator
HVY91_RS13665	COG0697	spore germination
HVY91_RS13685	COG2211	Major facilitator Superfamily
HVY91_RS13690	COG1501	Belongs to the glycosyl hydrolase 31 family
HVY91_RS13695	COG2982	Protein involved in outer membrane biogenesis
HVY91_RS13700	COG2233	PERMEase
HVY91_RS13705	COG0786	glutamate:sodium symporter activity
HVY91_RS13715	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HVY91_RS13720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HVY91_RS13725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HVY91_RS13735	COG0194	GDP metabolic process
HVY91_RS13745	COG2860	membrane
HVY91_RS13750	COG1561	YicC-like family, N-terminal region
HVY91_RS13780	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HVY91_RS13810	COG1519	Transferase
HVY91_RS13815	COG0859	PFAM glycosyl transferase family 9
HVY91_RS13820	COG0438	transferase activity, transferring glycosyl groups
HVY91_RS13825	COG0515	serine threonine protein kinase
HVY91_RS13835	COG0438	transferase activity, transferring glycosyl groups
HVY91_RS13840	COG1442	glycosyl transferase family 8
HVY91_RS13845	COG1442	glycosyl transferase family 8
HVY91_RS13850	COG3642	lipopolysaccharide core region biosynthetic process
HVY91_RS13870	COG0859	PFAM glycosyl transferase family 9
HVY91_RS13875	COG0859	PFAM glycosyl transferase family 9
HVY91_RS13885	COG0156	8-amino-7-oxononanoate synthase activity
HVY91_RS13900	COG2204	response regulator
HVY91_RS13905	COG3852	Histidine kinase
HVY91_RS13910	COG0174	glutamine synthetase
HVY91_RS13920	COG0561	phosphatase activity
HVY91_RS13930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HVY91_RS13950	COG1011	Hydrolase
HVY91_RS13965	COG0456	acetyltransferase
HVY91_RS13980	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HVY91_RS13990	COG2864	formate dehydrogenase
HVY91_RS13995	COG0437	4 iron, 4 sulfur cluster binding
HVY91_RS14010	COG0326	Molecular chaperone. Has ATPase activity
HVY91_RS14025	COG1470	cell adhesion involved in biofilm formation
HVY91_RS14025	COG1388	LysM domain
HVY91_RS14030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVY91_RS14030	COG3711	transcriptional antiterminator
HVY91_RS14035	COG1363	Peptidase, m42
HVY91_RS14040	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVY91_RS14040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVY91_RS14045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVY91_RS14055	COG1454	alcohol dehydrogenase
HVY91_RS14090	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HVY91_RS14095	COG2258	MOSC domain
HVY91_RS14100	COG2205	protein histidine kinase activity
HVY91_RS14105	COG0745	RESPONSE REGULATOR receiver
HVY91_RS14110	COG3678	ATP-independent chaperone mediated protein folding
HVY91_RS14125	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HVY91_RS14145	COG3152	Membrane
HVY91_RS14150	COG3691	Protein conserved in bacteria
HVY91_RS14155	COG0589	response to stress
HVY91_RS14165	COG1494	fructose-1,6-bisphosphatase
HVY91_RS14175	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HVY91_RS14190	COG1575	Belongs to the MenA family. Type 1 subfamily
HVY91_RS14205	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HVY91_RS14210	COG1609	Transcriptional regulator
HVY91_RS14215	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HVY91_RS14230	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HVY91_RS14240	COG0626	cystathionine gamma-synthase activity
HVY91_RS14245	COG0527	aspartate kinase activity
HVY91_RS14245	COG0460	homoserine dehydrogenase
HVY91_RS14255	COG0737	Belongs to the 5'-nucleotidase family
HVY91_RS14260	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HVY91_RS14270	COG0697	spore germination
HVY91_RS14275	COG3738	Protein conserved in bacteria
HVY91_RS14280	COG0371	Dehydrogenase
HVY91_RS14285	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HVY91_RS14290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HVY91_RS14290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVY91_RS14290	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVY91_RS14295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVY91_RS14300	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVY91_RS14305	COG1882	Formate acetyltransferase
HVY91_RS14310	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HVY91_RS14315	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVY91_RS14320	COG2207	Transcriptional regulator
HVY91_RS14325	COG2194	sulfuric ester hydrolase activity
HVY91_RS14340	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HVY91_RS14355	COG0583	DNA-binding transcription factor activity
HVY91_RS14365	COG1473	amidohydrolase
HVY91_RS14370	COG0477	Major facilitator Superfamily
HVY91_RS14375	COG1309	transcriptional regulator
HVY91_RS14420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HVY91_RS14425	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HVY91_RS14425	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HVY91_RS14460	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HVY91_RS14465	COG0250	Participates in transcription elongation, termination and antitermination
HVY91_RS14500	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HVY91_RS14510	COG2104	thiamine diphosphate biosynthetic process
HVY91_RS14515	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HVY91_RS14550	COG3068	Protein conserved in bacteria
HVY91_RS14565	COG3678	ATP-independent chaperone mediated protein folding
HVY91_RS14570	COG4191	Histidine kinase
HVY91_RS14575	COG2204	response regulator
HVY91_RS14580	COG0151	Belongs to the GarS family
HVY91_RS14610	COG0456	acetyltransferase
HVY91_RS14620	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HVY91_RS14625	COG2224	Isocitrate lyase
HVY91_RS14640	COG1414	Transcriptional regulator
HVY91_RS14645	COG0646	methionine synthase
HVY91_RS14645	COG1410	methionine synthase
HVY91_RS14660	COG1283	sodium-dependent phosphate transmembrane transporter activity
HVY91_RS14665	COG3122	Protein conserved in bacteria
HVY91_RS14705	COG1187	pseudouridine synthase activity
HVY91_RS14735	COG3541	Predicted nucleotidyltransferase
HVY91_RS14740	COG0542	response to heat
HVY91_RS14745	COG0527	aspartate kinase activity
HVY91_RS14770	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HVY91_RS14780	COG0477	Major facilitator Superfamily
HVY91_RS14780	COG2814	Major facilitator Superfamily
HVY91_RS14785	COG3833	ABC-type maltose transport systems, permease component
HVY91_RS14790	COG1175	transmembrane transport
HVY91_RS14795	COG2182	Extracellular solute-binding protein
HVY91_RS14800	COG3842	ATPase activity
HVY91_RS14830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HVY91_RS14840	COG0534	Mate efflux family protein
HVY91_RS14845	COG3237	CsbD-like
HVY91_RS14850	COG0735	belongs to the Fur family
HVY91_RS14855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HVY91_RS14865	COG0604	alcohol dehydrogenase
HVY91_RS14870	COG0305	Participates in initiation and elongation during chromosome replication
HVY91_RS14880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HVY91_RS14895	COG1448	Aminotransferase
HVY91_RS14900	COG0567	Dehydrogenase, E1 component
HVY91_RS14910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HVY91_RS14915	COG0045	succinate-CoA ligase (ADP-forming) activity
HVY91_RS14920	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HVY91_RS14925	COG0471	metal ion transport
HVY91_RS14930	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HVY91_RS14935	COG2204	response regulator
HVY91_RS14945	COG3700	Belongs to the class B bacterial acid phosphatase family
HVY91_RS14950	COG0432	Pfam Uncharacterised protein family UPF0047
HVY91_RS14955	COG2315	Protein conserved in bacteria
HVY91_RS14960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HVY91_RS14965	COG0629	single-stranded DNA binding
HVY91_RS14980	COG0789	Transcriptional regulator
HVY91_RS14985	COG2252	PERMEase
HVY91_RS14990	COG0025	NhaP-type Na H and K H
HVY91_RS14995	COG2824	Alkylphosphonate utilization operon protein PhnA
HVY91_RS15000	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HVY91_RS15015	COG0642	Histidine kinase
HVY91_RS15020	COG0745	RESPONSE REGULATOR receiver
HVY91_RS15025	COG2194	sulfuric ester hydrolase activity
HVY91_RS15030	COG2207	Transcriptional regulator
HVY91_RS15035	COG3647	Membrane
HVY91_RS15040	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HVY91_RS15040	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HVY91_RS15045	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HVY91_RS15050	COG4565	transcriptional regulatory protein
HVY91_RS15055	COG3290	protein histidine kinase activity
HVY91_RS15060	COG0243	molybdopterin cofactor binding
HVY91_RS15065	COG0437	4 iron, 4 sulfur cluster binding
HVY91_RS15070	COG3302	dmso reductase anchor subunit
HVY91_RS15075	COG3381	protein complex oligomerization
HVY91_RS15095	COG1309	transcriptional regulator
HVY91_RS15100	COG4232	protein-disulfide reductase activity
HVY91_RS15110	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HVY91_RS15115	COG1027	Aspartate ammonia-lyase
HVY91_RS15120	COG3030	protein affecting phage T7 exclusion by the F plasmid
HVY91_RS15125	COG0531	amino acid
HVY91_RS15150	COG1509	lysine 2,3-aminomutase activity
HVY91_RS15160	COG5510	response to toxic substance
HVY91_RS15165	COG5510	response to toxic substance
HVY91_RS15170	COG2076	Multidrug Resistance protein
HVY91_RS15175	COG3040	lipid binding
HVY91_RS15180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HVY91_RS15195	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HVY91_RS15200	COG1053	succinate dehydrogenase
HVY91_RS15210	COG0531	amino acid
HVY91_RS15225	COG3264	Mechanosensitive ion channel
HVY91_RS15225	COG1511	domain protein
HVY91_RS15245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVY91_RS15270	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HVY91_RS15275	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HVY91_RS15275	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HVY91_RS15280	COG0802	atpase or kinase
HVY91_RS15285	COG0860	N-Acetylmuramoyl-L-alanine amidase
HVY91_RS15305	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HVY91_RS15310	COG0330	HflC and HflK could
HVY91_RS15315	COG0330	HflC and HflK could
HVY91_RS15320	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HVY91_RS15335	COG0557	exoribonuclease II activity
HVY91_RS15340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HVY91_RS15345	COG3789	protein conserved in bacteria
HVY91_RS15350	COG1842	Phage shock protein A
HVY91_RS15360	COG3766	membrane
HVY91_RS15365	COG5463	Belongs to the UPF0441 family
HVY91_RS15370	COG0754	glutathionylspermidine amidase activity
HVY91_RS15375	COG1960	acyl-CoA dehydrogenase activity
HVY91_RS15385	COG3650	response to hydrogen peroxide
HVY91_RS15390	COG1073	alpha beta
HVY91_RS15405	COG3037	sugar-specific permease SgaT UlaA
HVY91_RS15410	COG3414	Phosphotransferase system galactitol-specific IIB component
HVY91_RS15450	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HVY91_RS15460	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HVY91_RS15470	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HVY91_RS15475	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HVY91_RS15480	COG4670	ketone body catabolic process
HVY91_RS15485	COG1024	Enoyl-CoA hydratase
HVY91_RS15500	COG1309	transcriptional regulator
HVY91_RS15505	COG3061	Opacity-associated protein A
HVY91_RS15510	COG0545	Peptidyl-prolyl cis-trans isomerase
HVY91_RS15515	COG1113	amino acid transport
HVY91_RS15525	COG0697	spore germination
HVY91_RS15530	COG0702	epimerase
HVY91_RS15535	COG1733	regulation of RNA biosynthetic process
HVY91_RS15540	COG0737	Belongs to the 5'-nucleotidase family
HVY91_RS15545	COG1218	3'(2'),5'-bisphosphate nucleotidase
HVY91_RS15550	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HVY91_RS15560	COG1253	flavin adenine dinucleotide binding
HVY91_RS15565	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HVY91_RS15575	COG0698	ribose 5-phosphate isomerase
HVY91_RS15580	COG1737	Transcriptional regulator
HVY91_RS15585	COG1879	ABC-type sugar transport system periplasmic component
HVY91_RS15590	COG1129	ABC transporter
HVY91_RS15595	COG1172	Belongs to the binding-protein-dependent transport system permease family
HVY91_RS15600	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HVY91_RS15605	COG1940	carbohydrate kinase activity
HVY91_RS15610	COG2015	COG2015, Alkyl sulfatase and related hydrolases
HVY91_RS15620	COG1566	PFAM secretion protein HlyD family protein
HVY91_RS15625	COG1289	transmembrane transporter activity
HVY91_RS15640	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HVY91_RS15645	COG1301	dicarboxylic acid transport
HVY91_RS15650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HVY91_RS15655	COG3162	membrane
HVY91_RS15670	COG0729	surface antigen
HVY91_RS15675	COG2911	Protein conserved in bacteria
HVY91_RS15680	COG2105	PFAM AIG2 family protein
HVY91_RS15685	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HVY91_RS15690	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HVY91_RS15695	COG1879	ABC-type sugar transport system periplasmic component
HVY91_RS15700	COG1129	ABC transporter
HVY91_RS15705	COG1172	Belongs to the binding-protein-dependent transport system permease family
HVY91_RS15710	COG1172	Belongs to the binding-protein-dependent transport system permease family
HVY91_RS15720	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HVY91_RS15730	COG0312	modulator of DNA gyrase
HVY91_RS15735	COG3783	Cytochrome b(562)
HVY91_RS15740	COG3077	Addiction module antitoxin, RelB DinJ family
HVY91_RS15750	COG0602	queuosine metabolic process
HVY91_RS15755	COG1328	CTP reductase activity
HVY91_RS15760	COG0366	Alpha amylase catalytic
HVY91_RS15765	COG1263	PTS System
HVY91_RS15765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVY91_RS15770	COG1609	Transcriptional regulator
HVY91_RS15780	COG0251	oxidation-reduction process
HVY91_RS15800	COG1438	arginine binding
HVY91_RS15805	COG1288	antiporter activity
HVY91_RS15810	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HVY91_RS15815	COG0549	Belongs to the carbamate kinase family
HVY91_RS15825	COG2731	YhcH YjgK YiaL family protein
HVY91_RS15830	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HVY91_RS15835	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
HVY91_RS15840	COG0456	acetyltransferase
HVY91_RS15850	COG0525	valine-tRNA ligase activity
HVY91_RS15855	COG2927	DNA polymerase III (CHI subunit)
HVY91_RS15870	COG0795	lipopolysaccharide-transporting ATPase activity
HVY91_RS15875	COG0795	lipopolysaccharide-transporting ATPase activity
HVY91_RS15880	COG2823	Periplasmic or secreted lipoprotein
HVY91_RS15900	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HVY91_RS15910	COG1063	alcohol dehydrogenase
HVY91_RS15915	COG3775	system Galactitol-specific IIC component
HVY91_RS15920	COG3414	Phosphotransferase system galactitol-specific IIB component
HVY91_RS15925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVY91_RS15940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVY91_RS15940	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVY91_RS15940	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVY91_RS15955	COG1349	DNA-binding transcription factor activity
HVY91_RS15960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVY91_RS15965	COG2721	sulfolactate sulfo-lyase activity
HVY91_RS15975	COG2084	Dehydrogenase
HVY91_RS15985	COG1741	Belongs to the pirin family
HVY91_RS15990	COG0583	DNA-binding transcription factor activity
HVY91_RS15995	COG3152	Membrane
HVY91_RS16000	COG0435	Glutathione S-transferase
HVY91_RS16005	COG2259	Doxx family
HVY91_RS16015	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HVY91_RS16020	COG4575	ribosome binding
HVY91_RS16025	COG1422	Protein of unknown function (DUF1090)
HVY91_RS16035	COG0586	Pfam SNARE associated Golgi protein
HVY91_RS16040	COG2186	Transcriptional regulator
HVY91_RS16045	COG2271	Major facilitator Superfamily
HVY91_RS16055	COG2721	sulfolactate sulfo-lyase activity
HVY91_RS16065	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HVY91_RS16070	COG0861	Integral membrane protein TerC family
HVY91_RS16075	COG0673	inositol 2-dehydrogenase activity
HVY91_RS16080	COG2949	membrane
HVY91_RS16085	COG1451	nucleotide metabolic process
HVY91_RS16110	COG1484	DNA-dependent DNA replication
HVY91_RS16125	COG2966	Psort location CytoplasmicMembrane, score
HVY91_RS16135	COG2169	Transcriptional regulator
HVY91_RS16135	COG1917	Cupin 2, conserved barrel domain protein
HVY91_RS16140	COG2197	response regulator
HVY91_RS16145	COG2197	response regulator
HVY91_RS16150	COG4114	ferric iron reductase
HVY91_RS16180	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HVY91_RS16185	COG0456	acetyltransferase
HVY91_RS16190	COG1011	Hydrolase
HVY91_RS16210	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
HVY91_RS16215	COG5532	Uncharacterized conserved protein (DUF2303)
HVY91_RS16260	COG1846	Transcriptional regulator
HVY91_RS16265	COG4725	Belongs to the MT-A70-like family
HVY91_RS16270	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HVY91_RS16280	COG1403	HNH endonuclease
HVY91_RS16285	COG0484	heat shock protein binding
HVY91_RS16295	COG1278	Cold shock
HVY91_RS16300	COG1278	Cold shock
HVY91_RS16320	COG3772	lysozyme
HVY91_RS16330	COG1278	Cold shock
HVY91_RS16375	COG0740	serine-type endopeptidase activity
HVY91_RS16450	COG5301	cellulose 1,4-beta-cellobiosidase activity
HVY91_RS16455	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HVY91_RS16460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HVY91_RS16485	COG2823	Periplasmic or secreted lipoprotein
HVY91_RS16495	COG4667	esterase of the alpha-beta hydrolase superfamily
HVY91_RS16500	COG0084	hydrolase, TatD family'
HVY91_RS16505	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HVY91_RS16510	COG1328	CTP reductase activity
HVY91_RS16545	COG3726	membrane protein affecting hemolysin expression
HVY91_RS16550	COG0560	Phosphoserine phosphatase
HVY91_RS16555	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HVY91_RS16560	COG1056	cytidyltransferase-related domain
HVY91_RS16560	COG3172	ATPase kinase involved in NAD metabolism
HVY91_RS16565	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
HVY91_RS16575	COG0488	(ABC) transporter
HVY91_RS16580	COG0741	lytic transglycosylase activity
HVY91_RS16600	COG3708	Transcriptional regulator
HVY91_RS16600	COG2207	Transcriptional regulator
HVY91_RS16605	COG3045	CreA protein
HVY91_RS16610	COG0745	RESPONSE REGULATOR receiver
HVY91_RS16615	COG2205	protein histidine kinase activity
HVY91_RS16620	COG4452	Inner membrane protein CreD
HVY91_RS16625	COG0745	RESPONSE REGULATOR receiver
HVY91_RS16635	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HVY91_RS16645	COG0527	aspartate kinase activity
HVY91_RS16645	COG0460	homoserine dehydrogenase
HVY91_RS16655	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HVY91_RS16670	COG1115	amino acid carrier protein
HVY91_RS16680	COG0521	Mo-molybdopterin cofactor biosynthetic process
HVY91_RS16685	COG1584	GPR1 FUN34 yaaH family protein
HVY91_RS16710	COG0583	DNA-binding transcription factor activity
HVY91_RS16725	COG0196	riboflavin kinase activity
HVY91_RS16740	COG1047	Peptidyl-prolyl cis-trans
HVY91_RS16770	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
HVY91_RS16775	COG0511	ligase activity, forming carbon-carbon bonds
HVY91_RS16775	COG5016	pyruvate
HVY91_RS16830	COG0505	Belongs to the CarA family
HVY91_RS16835	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HVY91_RS16885	COG0644	oxidoreductase
HVY91_RS16890	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HVY91_RS16895	COG2271	Major facilitator Superfamily
HVY91_RS16910	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HVY91_RS16950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HVY91_RS16960	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HVY91_RS16965	COG0564	pseudouridine synthase activity
HVY91_RS16975	COG0417	DNA replication proofreading
HVY91_RS17000	COG0235	Class ii aldolase
HVY91_RS17020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVY91_RS17030	COG3181	Tripartite tricarboxylate transporter family receptor
HVY91_RS17045	COG0586	Pfam SNARE associated Golgi protein
HVY91_RS17055	COG1178	ABC-type Fe3 transport system permease component
HVY91_RS17060	COG4143	(ABC) transporter
HVY91_RS17075	COG2814	Major facilitator Superfamily
HVY91_RS17080	COG2271	Major facilitator Superfamily
HVY91_RS17085	COG0583	DNA-binding transcription factor activity
HVY91_RS17095	COG0738	Major facilitator superfamily
HVY91_RS17140	COG0028	Belongs to the TPP enzyme family
HVY91_RS17145	COG0440	acetolactate synthase activity
HVY91_RS17155	COG1609	Transcriptional regulator
HVY91_RS17170	COG3116	cell division
HVY91_RS17175	COG0768	penicillin binding
HVY91_RS17180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HVY91_RS17185	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HVY91_RS17200	COG0772	Belongs to the SEDS family
HVY91_RS17215	COG1181	Belongs to the D-alanine--D-alanine ligase family
HVY91_RS17220	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HVY91_RS17225	COG0849	cell division
HVY91_RS17230	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HVY91_RS17250	COG0494	nUDIX hydrolase
HVY91_RS17265	COG0237	dephospho-CoA kinase activity
HVY91_RS17275	COG1459	type II secretion system
HVY91_RS17280	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HVY91_RS17285	COG4969	Belongs to the N-Me-Phe pilin family
HVY91_RS17290	COG0157	Belongs to the NadC ModD family
HVY91_RS17295	COG3023	N-Acetylmuramoyl-L-alanine amidase
HVY91_RS17300	COG3725	Membrane protein required for beta-lactamase induction
HVY91_RS17305	COG1113	amino acid transport
HVY91_RS17310	COG2186	Transcriptional regulator
HVY91_RS17315	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HVY91_RS17320	COG0508	dehydrogenase complex catalyzes the overall conversion of
HVY91_RS17325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HVY91_RS17330	COG3064	Membrane
HVY91_RS17335	COG1049	propionate catabolic process, 2-methylcitrate cycle
HVY91_RS17360	COG2132	Multicopper oxidase
HVY91_RS17365	COG4993	Dehydrogenase
HVY91_RS17370	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HVY91_RS17375	COG0288	reversible hydration of carbon dioxide
HVY91_RS17380	COG1131	(ABC) transporter
HVY91_RS17385	COG0842	Transport permease protein
HVY91_RS17390	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVY91_RS17395	COG0726	polysaccharide deacetylase
HVY91_RS17405	COG5464	transposase or invertase
HVY91_RS17420	COG3539	Fimbrial protein
HVY91_RS17425	COG3539	Fimbrial protein
HVY91_RS17430	COG3539	Fimbrial protein
HVY91_RS17435	COG3539	Fimbrial protein
HVY91_RS17440	COG3188	usher protein
HVY91_RS17445	COG3121	Chaperone
HVY91_RS17450	COG3539	Fimbrial protein
HVY91_RS17455	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HVY91_RS17460	COG0617	tRNA 3'-terminal CCA addition
HVY91_RS17470	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HVY91_RS17480	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HVY91_RS17485	COG1643	Atp-dependent helicase
HVY91_RS17490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HVY91_RS17495	COG4774	siderophore transport
HVY91_RS17500	COG1120	ATPase activity
HVY91_RS17505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HVY91_RS17510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HVY91_RS17535	COG2860	membrane
HVY91_RS17540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HVY91_RS17555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HVY91_RS17560	COG3835	regulator
HVY91_RS17570	COG1408	metallophosphoesterase
HVY91_RS17585	COG0024	Methionine aminopeptidase
HVY91_RS17610	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HVY91_RS17615	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HVY91_RS17620	COG0575	Belongs to the CDS family
HVY91_RS17625	COG0750	zinc metalloprotease
HVY91_RS17635	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HVY91_RS17640	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HVY91_RS17665	COG0587	DNA-directed DNA polymerase activity
HVY91_RS17680	COG0346	lactoylglutathione lyase activity
HVY91_RS17685	COG0037	tRNA processing
HVY91_RS17690	COG4568	rho-dependent transcription termination
HVY91_RS17700	COG4681	YaeQ
HVY91_RS17705	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HVY91_RS17710	COG3015	lipoprotein NlpE involved in copper resistance
HVY91_RS17715	COG0791	NLP P60 protein
HVY91_RS17725	COG1720	tRNA m6t6A37 methyltransferase activity
HVY91_RS17735	COG1464	Belongs to the NlpA lipoprotein family
HVY91_RS17740	COG2011	ABC-type metal ion transport system permease component
HVY91_RS17745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HVY91_RS17750	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HVY91_RS17785	COG0656	L-ascorbic acid biosynthetic process
HVY91_RS17790	COG0583	DNA-binding transcription factor activity
HVY91_RS17800	COG2226	methyltransferase
HVY91_RS17805	COG1388	LysM domain
HVY91_RS17805	COG0741	lytic transglycosylase activity
HVY91_RS17815	COG2226	methyltransferase
HVY91_RS17825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HVY91_RS17835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HVY91_RS17845	COG1960	acyl-CoA dehydrogenase activity
HVY91_RS17855	COG0121	glutamine amidotransferase
HVY91_RS17860	COG3034	peptidoglycan biosynthetic process
HVY91_RS17865	COG0791	NLP P60 protein
HVY91_RS17875	COG0860	N-Acetylmuramoyl-L-alanine amidase
HVY91_RS17895	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HVY91_RS17900	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HVY91_RS17905	COG2166	iron-sulfur cluster assembly
HVY91_RS17910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HVY91_RS17920	COG0583	DNA-binding transcription factor activity
HVY91_RS17925	COG2363	Small membrane protein
HVY91_RS17940	COG1760	l-serine dehydratase
HVY91_RS17945	COG0814	amino acid
HVY91_RS17950	COG1611	Belongs to the LOG family
HVY91_RS17965	COG3098	single-species biofilm formation
HVY91_RS17970	COG0564	pseudouridine synthase activity
HVY91_RS17975	COG0716	FMN binding
HVY91_RS17995	COG4948	Mandelate Racemase Muconate Lactonizing
HVY91_RS18000	COG4948	Mandelate Racemase Muconate Lactonizing
HVY91_RS18005	COG1929	Belongs to the glycerate kinase type-1 family
HVY91_RS18010	COG3437	response regulator, receiver
HVY91_RS18010	COG3850	Histidine kinase
HVY91_RS18010	COG2205	protein histidine kinase activity
HVY91_RS18010	COG4999	Histidine kinase
HVY91_RS18015	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HVY91_RS18020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HVY91_RS18025	COG3956	TIGRFAM MazG family protein
HVY91_RS18040	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HVY91_RS18050	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HVY91_RS18060	COG0602	queuosine metabolic process
HVY91_RS18070	COG0720	synthase
HVY91_RS18095	COG1203	CRISPR-associated helicase, Cas3
HVY91_RS18110	COG1857	crispr-associated protein
HVY91_RS18125	COG1518	maintenance of DNA repeat elements
HVY91_RS18130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HVY91_RS18135	COG2234	aminopeptidase activity
HVY91_RS18190	COG1388	LysM domain
HVY91_RS18190	COG4942	peptidase
HVY91_RS18195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HVY91_RS18205	COG0163	prenyltransferase activity
HVY91_RS18210	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HVY91_RS18220	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HVY91_RS18260	COG1129	ABC transporter
HVY91_RS18265	COG1172	Belongs to the binding-protein-dependent transport system permease family
HVY91_RS18270	COG1879	ABC-type sugar transport system periplasmic component
HVY91_RS18275	COG1349	DNA-binding transcription factor activity
HVY91_RS18290	COG3604	Transcriptional regulator
HVY91_RS18295	COG0309	Hydrogenase expression formation protein (HypE)
HVY91_RS18300	COG0409	Hydrogenase expression formation protein
HVY91_RS18305	COG0298	carbon dioxide binding
HVY91_RS18310	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HVY91_RS18315	COG0375	protein maturation
HVY91_RS18325	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVY91_RS18330	COG0651	ATP synthesis coupled electron transport
HVY91_RS18335	COG0650	Formate hydrogenlyase subunit 4
HVY91_RS18340	COG3261	NADH dehydrogenase
HVY91_RS18340	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HVY91_RS18345	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HVY91_RS18350	COG3260	NADH ubiquinone oxidoreductase 20
HVY91_RS18360	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HVY91_RS18365	COG2723	6-phospho-beta-galactosidase activity
HVY91_RS18370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVY91_RS18370	COG1263	PTS System
HVY91_RS18375	COG1609	Transcriptional regulator
HVY91_RS18380	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVY91_RS18385	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HVY91_RS18405	COG0517	IMP dehydrogenase activity
HVY91_RS18405	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HVY91_RS18415	COG2951	lytic endotransglycosylase activity
HVY91_RS18425	COG1546	Belongs to the CinA family
HVY91_RS18445	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HVY91_RS18475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HVY91_RS18480	COG1238	metal cluster binding
HVY91_RS18495	COG2814	Major facilitator Superfamily
HVY91_RS18500	COG1566	PFAM secretion protein HlyD family protein
HVY91_RS18505	COG1846	Transcriptional regulator
HVY91_RS18515	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HVY91_RS18520	COG2814	Major facilitator Superfamily
HVY91_RS18525	COG2113	Glycine betaine
HVY91_RS18530	COG4176	ABC-type proline glycine betaine transport system permease component
HVY91_RS18535	COG4175	Glycine betaine
HVY91_RS18540	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HVY91_RS18545	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HVY91_RS18555	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HVY91_RS18560	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HVY91_RS18570	COG4575	ribosome binding
HVY91_RS18590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HVY91_RS18595	COG0640	Transcriptional regulator
HVY91_RS18600	COG0401	homolog of Blt101
HVY91_RS18605	COG1652	LysM domain
HVY91_RS18610	COG1802	Transcriptional regulator
HVY91_RS18615	COG1113	amino acid transport
HVY91_RS18620	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HVY91_RS18625	COG1012	belongs to the aldehyde dehydrogenase family
HVY91_RS18630	COG0579	oxidoreductase
HVY91_RS18640	COG0583	DNA-binding transcription factor activity
HVY91_RS18650	COG0666	response to abiotic stimulus
HVY91_RS18660	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HVY91_RS18665	COG1304	FMN binding
HVY91_RS18670	COG0549	Belongs to the carbamate kinase family
HVY91_RS18675	COG0402	S-adenosylhomocysteine deaminase activity
HVY91_RS18680	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HVY91_RS18690	COG1064	alcohol dehydrogenase
HVY91_RS18695	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HVY91_RS18700	COG0698	ribose 5-phosphate isomerase
HVY91_RS18710	COG2376	Dihydroxyacetone kinase
HVY91_RS18715	COG0149	triose-phosphate isomerase activity
HVY91_RS18720	COG1082	Xylose isomerase domain protein TIM barrel
HVY91_RS18725	COG2084	Dehydrogenase
HVY91_RS18730	COG2390	Transcriptional regulator
HVY91_RS18735	COG0393	Putative heavy-metal-binding
HVY91_RS18790	COG1204	response to ionizing radiation
HVY91_RS18795	COG0582	viral genome integration into host DNA
HVY91_RS18810	COG2867	negative regulation of translational initiation
HVY91_RS18820	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HVY91_RS18825	COG0497	DNA recombination
HVY91_RS18840	COG4536	flavin adenine dinucleotide binding
HVY91_RS18845	COG4137	Cytochrome C assembly protein
HVY91_RS18850	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HVY91_RS18880	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HVY91_RS18885	COG1605	Chorismate mutase
HVY91_RS18885	COG0287	Prephenate dehydrogenase
HVY91_RS18890	COG0077	Prephenate dehydratase
HVY91_RS18890	COG1605	Chorismate mutase
HVY91_RS18900	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HVY91_RS18905	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HVY91_RS18910	COG0564	pseudouridine synthase activity
HVY91_RS18920	COG0542	response to heat
HVY91_RS18945	COG0477	Major facilitator Superfamily
HVY91_RS18950	COG5544	Lipoprotein
HVY91_RS18955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HVY91_RS18960	COG1042	CoA-binding domain protein
HVY91_RS18960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HVY91_RS18960	COG0045	succinate-CoA ligase (ADP-forming) activity
HVY91_RS18970	COG3118	belongs to the thioredoxin family
HVY91_RS18975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HVY91_RS19000	COG0513	Belongs to the DEAD box helicase family
HVY91_RS19010	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HVY91_RS19020	COG1595	DNA-templated transcription, initiation
HVY91_RS19025	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
HVY91_RS19030	COG3026	antisigma factor binding
HVY91_RS19035	COG3086	response to oxidative stress
HVY91_RS19045	COG0681	Belongs to the peptidase S26 family
HVY91_RS19065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HVY91_RS19080	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVY91_RS19085	COG1737	Transcriptional regulator
HVY91_RS19090	COG0560	Phosphoserine phosphatase
HVY91_RS19095	COG0590	tRNA wobble adenosine to inosine editing
HVY91_RS19105	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HVY91_RS19105	COG0047	phosphoribosylformylglycinamidine synthase activity
HVY91_RS19110	COG2205	protein histidine kinase activity
HVY91_RS19115	COG3170	Tfp pilus assembly protein FimV
HVY91_RS19120	COG2204	response regulator
HVY91_RS19125	COG0347	Belongs to the P(II) protein family
HVY91_RS19145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HVY91_RS19160	COG4651	solute:proton antiporter activity
HVY91_RS19160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HVY91_RS19165	COG2223	nitrite transmembrane transporter activity
HVY91_RS19170	COG0737	Belongs to the 5'-nucleotidase family
HVY91_RS19175	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HVY91_RS19180	COG3735	TraB family
HVY91_RS19190	COG2217	Heavy metal translocating P-type atpase
HVY91_RS19195	COG0531	amino acid
HVY91_RS19225	COG0789	Transcriptional regulator
HVY91_RS19230	COG1585	Membrane protein implicated in regulation of membrane protease activity
HVY91_RS19235	COG0330	HflC and HflK could
HVY91_RS19240	COG4619	ABC transporter
HVY91_RS19245	COG0390	transport system, permease component
HVY91_RS19250	COG3118	belongs to the thioredoxin family
HVY91_RS19255	COG0300	oxidoreductase activity
HVY91_RS19260	COG2755	lipolytic protein G-D-S-L family
HVY91_RS19265	COG4181	ATPase activity
HVY91_RS19270	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HVY91_RS19290	COG0549	Belongs to the carbamate kinase family
HVY91_RS19295	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HVY91_RS19300	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HVY91_RS19315	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HVY91_RS19325	COG1988	membrane-bound metal-dependent
HVY91_RS19330	COG2501	S4 domain
HVY91_RS19345	COG1017	nitric oxide dioxygenase activity
HVY91_RS19345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HVY91_RS19355	COG2259	Doxx family
HVY91_RS19360	COG2814	Major facilitator Superfamily
HVY91_RS19365	COG3711	transcriptional antiterminator
HVY91_RS19370	COG1073	alpha beta
HVY91_RS19375	COG0483	inositol monophosphate 1-phosphatase activity
HVY91_RS19395	COG0822	iron-sulfur transferase activity
HVY91_RS19415	COG0633	Ferredoxin
HVY91_RS19420	COG2975	iron-sulfur cluster assembly
HVY91_RS19435	COG2897	thiosulfate sulfurtransferase activity
HVY91_RS19440	COG2373	Large extracellular alpha-helical protein
HVY91_RS19445	COG4953	penicillin-binding protein 1C
HVY91_RS19475	COG2976	Protein conserved in bacteria
HVY91_RS19490	COG1645	bacterial-type flagellum-dependent swarming motility
HVY91_RS19515	COG0516	GMP reductase activity
HVY91_RS19515	COG0517	IMP dehydrogenase activity
HVY91_RS19535	COG3133	Outer membrane lipoprotein
HVY91_RS19545	COG2200	EAL domain
HVY91_RS19550	COG0248	Ppx GppA phosphatase
HVY91_RS19560	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HVY91_RS19575	COG2233	PERMEase
HVY91_RS19585	COG1393	Belongs to the ArsC family
HVY91_RS19590	COG4783	chaperone-mediated protein folding
HVY91_RS19595	COG0628	permease
HVY91_RS19600	COG3604	Transcriptional regulator
HVY91_RS19610	COG3260	NADH ubiquinone oxidoreductase 20
HVY91_RS19615	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HVY91_RS19620	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HVY91_RS19620	COG3261	NADH dehydrogenase
HVY91_RS19625	COG0651	ATP synthesis coupled electron transport
HVY91_RS19630	COG4237	Hydrogenase 4 membrane
HVY91_RS19635	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HVY91_RS19640	COG0650	Formate hydrogenlyase subunit 4
HVY91_RS19645	COG0651	ATP synthesis coupled electron transport
HVY91_RS19650	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVY91_RS19655	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HVY91_RS19660	COG2716	regulation of RNA biosynthetic process
HVY91_RS19670	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HVY91_RS19680	COG2321	neutral zinc metallopeptidase
HVY91_RS19690	COG0400	carboxylic ester hydrolase activity
HVY91_RS19705	COG1393	Belongs to the ArsC family
HVY91_RS19715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HVY91_RS19720	COG3850	Histidine kinase
HVY91_RS19725	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HVY91_RS19725	COG0493	'glutamate synthase
HVY91_RS19735	COG5342	invasion associated locus B
HVY91_RS19740	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HVY91_RS19745	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HVY91_RS19750	COG0281	malic enzyme
HVY91_RS19750	COG0280	phosphate acetyltransferase
HVY91_RS19755	COG4810	utilization protein
HVY91_RS19760	COG4917	ethanolamine utilization protein
HVY91_RS19765	COG4766	ethanolamine catabolic process
HVY91_RS19770	COG4812	Cobalamin adenosyltransferase
HVY91_RS19775	COG0280	phosphate acetyltransferase
HVY91_RS19780	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HVY91_RS19785	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
HVY91_RS19790	COG1012	belongs to the aldehyde dehydrogenase family
HVY91_RS19795	COG4820	ethanolamine utilization protein (EutJ)
HVY91_RS19800	COG1454	alcohol dehydrogenase
HVY91_RS19805	COG3192	ethanolamine utilization protein
HVY91_RS19810	COG4819	ethanolamine utilization protein
HVY91_RS19815	COG4303	Ethanolamine ammonia lyase large subunit
HVY91_RS19825	COG4816	utilization protein
HVY91_RS19830	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HVY91_RS19835	COG2207	Transcriptional regulator
HVY91_RS19855	COG0860	N-Acetylmuramoyl-L-alanine amidase
HVY91_RS19875	COG2837	iron assimilation
HVY91_RS19880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HVY91_RS19885	COG1263	PTS System
HVY91_RS19885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HVY91_RS19900	COG1028	Short-chain dehydrogenase reductase Sdr
HVY91_RS19905	COG4150	thiosulfate binding
HVY91_RS19910	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HVY91_RS19915	COG4208	sulfate ABC transporter
HVY91_RS19920	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HVY91_RS19925	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HVY91_RS19940	COG2190	(PTS) system
HVY91_RS19945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HVY91_RS19950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HVY91_RS19955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HVY91_RS19965	COG3115	cell septum assembly
HVY91_RS19975	COG3530	Putative quorum-sensing-regulated virulence factor
HVY91_RS19980	COG0385	Bile acid
HVY91_RS19990	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HVY91_RS19995	COG2211	Major facilitator Superfamily
HVY91_RS20005	COG0583	DNA-binding transcription factor activity
HVY91_RS20030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HVY91_RS20035	COG3415	Transposase
HVY91_RS20040	COG3415	Transposase
HVY91_RS20055	COG2199	diguanylate cyclase activity
HVY91_RS20055	COG2200	EAL domain
HVY91_RS20060	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HVY91_RS20085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVY91_RS20090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HVY91_RS20095	COG0006	proline dipeptidase activity
HVY91_RS20100	COG1363	Peptidase, m42
HVY91_RS20110	COG2207	Transcriptional regulator
HVY91_RS20115	COG3279	Response regulator of the LytR AlgR family
HVY91_RS20120	COG3275	phosphorelay sensor kinase activity
HVY91_RS20125	COG0436	Aminotransferase
HVY91_RS20135	COG1560	Kdo2-lipid A biosynthetic process
HVY91_RS20155	COG0154	amidase activity
HVY91_RS20175	COG4638	Rieske (2fe-2S)
HVY91_RS20185	COG1028	Short-chain dehydrogenase reductase Sdr
HVY91_RS20195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HVY91_RS20230	COG0463	Glycosyl transferase, family 2
HVY91_RS20235	COG2246	polysaccharide biosynthetic process
HVY91_RS20255	COG2116	formate transmembrane transporter activity
HVY91_RS20265	COG2067	long-chain fatty acid transport protein
HVY91_RS20270	COG3691	Protein conserved in bacteria
HVY91_RS20285	COG2062	phosphohistidine phosphatase, SixA
HVY91_RS20290	COG3539	Fimbrial protein
HVY91_RS20295	COG3188	usher protein
HVY91_RS20300	COG3121	Chaperone
HVY91_RS20305	COG3539	Fimbrial protein
HVY91_RS20310	COG3539	Fimbrial protein
HVY91_RS20315	COG3539	Fimbrial protein
HVY91_RS20345	COG0730	response to heat
HVY91_RS20350	COG3101	peptidyl-lysine hydroxylation
HVY91_RS20365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HVY91_RS20385	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HVY91_RS20395	COG0586	Pfam SNARE associated Golgi protein
HVY91_RS20405	COG0285	dihydrofolate synthase activity
HVY91_RS20410	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HVY91_RS20415	COG1286	toxin biosynthetic process
HVY91_RS20420	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HVY91_RS20425	COG0163	prenyltransferase activity
HVY91_RS20430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVY91_RS20435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVY91_RS20440	COG4215	(ABC) transporter
HVY91_RS20445	COG4160	amino acid transport
HVY91_RS20450	COG4598	ABC transporter
HVY91_RS20455	COG5464	transposase or invertase
HVY91_RS20460	COG1090	epimerase
HVY91_RS20465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HVY91_RS20470	COG0625	glutathione transferase activity
HVY91_RS20475	COG0625	glutathione transferase activity
HVY91_RS20480	COG0622	Phosphoesterase
HVY91_RS20490	COG1609	Transcriptional regulator
HVY91_RS20505	COG3037	sugar-specific permease SgaT UlaA
HVY91_RS20510	COG3959	Transketolase, thiamine diphosphate binding domain
HVY91_RS20515	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HVY91_RS20525	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HVY91_RS20540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HVY91_RS20545	COG0490	domain, Protein
HVY91_RS20545	COG0471	metal ion transport
HVY91_RS20555	COG0436	Aminotransferase
HVY91_RS20560	COG0583	DNA-binding transcription factor activity
HVY91_RS20580	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HVY91_RS20585	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HVY91_RS20590	COG1034	ATP synthesis coupled electron transport
HVY91_RS20605	COG0839	Belongs to the complex I subunit 6 family
HVY91_RS20615	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HVY91_RS20620	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HVY91_RS20645	COG2304	oxidoreductase activity
HVY91_RS20650	COG0835	chemotaxis
HVY91_RS20650	COG0784	Response regulator, receiver
HVY91_RS20660	COG2153	protein acetylation
HVY91_RS20665	COG4575	ribosome binding
HVY91_RS20670	COG1169	isochorismate synthase
HVY91_RS20685	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HVY91_RS20695	COG0318	PFAM AMP-dependent synthetase and ligase
HVY91_RS20765	COG5464	transposase or invertase
HVY91_RS20770	COG0247	lactate metabolic process
HVY91_RS20780	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HVY91_RS20785	COG2271	Major facilitator Superfamily
HVY91_RS20790	COG0584	glycerophosphoryl diester phosphodiesterase
HVY91_RS20795	COG3642	lipopolysaccharide core region biosynthetic process
HVY91_RS20800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HVY91_RS20805	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HVY91_RS20810	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HVY91_RS20815	COG3468	outer membrane autotransporter barrel domain protein
HVY91_RS20825	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HVY91_RS20830	COG0183	Belongs to the thiolase family
HVY91_RS20835	COG2031	fatty acid transporter
HVY91_RS20840	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HVY91_RS20845	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HVY91_RS20850	COG2204	response regulator
HVY91_RS20855	COG3852	Histidine kinase
HVY91_RS20860	COG2205	protein histidine kinase activity
HVY91_RS20860	COG0784	Response regulator, receiver
HVY91_RS20865	COG2197	response regulator
HVY91_RS20870	COG0642	Histidine kinase
HVY91_RS20870	COG2198	Histidine kinase
HVY91_RS20875	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HVY91_RS20880	COG1477	protein flavinylation
HVY91_RS20885	COG2169	Transcriptional regulator
HVY91_RS20885	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HVY91_RS20890	COG3145	DNA-N1-methyladenine dioxygenase activity
HVY91_RS20895	COG4615	Cyclic peptide transporter
HVY91_RS20905	COG1126	abc transporter atp-binding protein
HVY91_RS20910	COG0765	amino acid transport
HVY91_RS20915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVY91_RS20925	COG5006	permease, DMT superfamily
HVY91_RS20930	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HVY91_RS20935	COG2194	sulfuric ester hydrolase activity
HVY91_RS20945	COG1321	iron dependent repressor
HVY91_RS20950	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HVY91_RS20955	COG1376	ErfK ybiS ycfS ynhG family protein
HVY91_RS20960	COG0488	(ABC) transporter
HVY91_RS20970	COG0561	phosphatase activity
HVY91_RS20975	COG1882	Formate acetyltransferase
HVY91_RS20980	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HVY91_RS20985	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HVY91_RS20990	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HVY91_RS20995	COG0303	'Molybdopterin
HVY91_RS21020	COG2200	EAL domain
HVY91_RS21025	COG2199	diguanylate cyclase activity
HVY91_RS21040	COG2133	pyrroloquinoline quinone binding
HVY91_RS21045	COG0625	glutathione transferase activity
HVY91_RS21050	COG1686	Belongs to the peptidase S11 family
HVY91_RS21055	COG1349	DNA-binding transcription factor activity
HVY91_RS21060	COG0671	phosphoesterase, PA-phosphatase related
HVY91_RS21065	COG2814	Major facilitator Superfamily
HVY91_RS21075	COG0561	phosphatase activity
HVY91_RS21080	COG0738	Major facilitator superfamily
HVY91_RS21085	COG3226	Transcriptional regulator
HVY91_RS21105	COG0778	Nitroreductase
HVY91_RS21120	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HVY91_RS21125	COG3842	ATPase activity
HVY91_RS21130	COG1176	ABC-type spermidine putrescine transport system, permease component I
HVY91_RS21135	COG1177	transmembrane transport
HVY91_RS21150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVY91_RS21155	COG4160	amino acid transport
HVY91_RS21160	COG4215	(ABC) transporter
HVY91_RS21165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HVY91_RS21170	COG1126	abc transporter atp-binding protein
HVY91_RS21185	COG3023	N-Acetylmuramoyl-L-alanine amidase
HVY91_RS21190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HVY91_RS21195	COG0702	epimerase
HVY91_RS21200	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HVY91_RS21205	COG0028	Belongs to the TPP enzyme family
HVY91_RS21215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HVY91_RS21225	COG2431	L-lysine efflux transmembrane transporter activity
HVY91_RS21235	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HVY91_RS21240	COG3593	DNA synthesis involved in DNA repair
HVY91_RS21245	COG2990	Protein conserved in bacteria
HVY91_RS21250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HVY91_RS21260	COG1278	Cold shock
HVY91_RS21270	COG0542	response to heat
HVY91_RS21290	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HVY91_RS21295	COG4988	ABC transporter
HVY91_RS21300	COG0492	ferredoxin-NADP+ reductase activity
HVY91_RS21305	COG1522	sequence-specific DNA binding
HVY91_RS21310	COG1674	ftsk spoiiie
HVY91_RS21310	COG1178	ABC-type Fe3 transport system permease component
HVY91_RS21320	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HVY91_RS21330	COG1335	isochorismatase
HVY91_RS21340	COG0531	amino acid
HVY91_RS21350	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HVY91_RS21355	COG4974	Belongs to the 'phage' integrase family
HVY91_RS21400	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HVY91_RS21405	COG1140	nitrate reductase beta subunit
HVY91_RS21410	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HVY91_RS21415	COG2181	nitrate reductase activity
HVY91_RS21420	COG0384	phenazine biosynthesis protein PhzF
HVY91_RS21425	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HVY91_RS21515	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HVY91_RS21680	COG5301	cellulose 1,4-beta-cellobiosidase activity
HVY91_RS21690	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HVY91_RS21755	COG0629	single-stranded DNA binding
HVY91_RS21870	COG3039	Transposase
HVY91_RS21875	COG2223	nitrite transmembrane transporter activity