locus-tag	class	description
C1192_RS00020	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C1192_RS00030	COG0582	viral genome integration into host DNA
C1192_RS00040	COG2116	formate transmembrane transporter activity
C1192_RS00055	COG2067	long-chain fatty acid transport protein
C1192_RS00065	COG3691	Protein conserved in bacteria
C1192_RS00075	COG1024	Enoyl-CoA hydratase
C1192_RS00075	COG1250	3-hydroxyacyl-CoA dehydrogenase
C1192_RS00080	COG2062	phosphohistidine phosphatase, SixA
C1192_RS00105	COG0730	response to heat
C1192_RS00110	COG3101	peptidyl-lysine hydroxylation
C1192_RS00125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C1192_RS00130	COG2814	Major facilitator Superfamily
C1192_RS00270	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C1192_RS00280	COG0586	Pfam SNARE associated Golgi protein
C1192_RS00290	COG0285	dihydrofolate synthase activity
C1192_RS00295	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C1192_RS00300	COG1286	toxin biosynthetic process
C1192_RS00305	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C1192_RS00310	COG0163	prenyltransferase activity
C1192_RS00315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1192_RS00320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1192_RS00325	COG4215	(ABC) transporter
C1192_RS00330	COG4160	amino acid transport
C1192_RS00335	COG4598	ABC transporter
C1192_RS00340	COG5464	transposase or invertase
C1192_RS00345	COG1090	epimerase
C1192_RS00350	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C1192_RS00355	COG0625	glutathione transferase activity
C1192_RS00360	COG0625	glutathione transferase activity
C1192_RS00365	COG0622	Phosphoesterase
C1192_RS00370	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C1192_RS00375	COG1609	Transcriptional regulator
C1192_RS00390	COG3037	sugar-specific permease SgaT UlaA
C1192_RS00395	COG3959	Transketolase, thiamine diphosphate binding domain
C1192_RS00400	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C1192_RS00405	COG1288	antiporter activity
C1192_RS00410	COG0280	phosphate acetyltransferase
C1192_RS00410	COG0857	belongs to the CobB CobQ family
C1192_RS00415	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C1192_RS00425	COG3385	transposase activity
C1192_RS00435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1192_RS00440	COG0471	metal ion transport
C1192_RS00440	COG0490	domain, Protein
C1192_RS00450	COG0436	Aminotransferase
C1192_RS00455	COG0583	DNA-binding transcription factor activity
C1192_RS00475	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
C1192_RS00480	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C1192_RS00485	COG1034	ATP synthesis coupled electron transport
C1192_RS00500	COG0839	Belongs to the complex I subunit 6 family
C1192_RS00510	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C1192_RS00515	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C1192_RS00530	COG2234	aminopeptidase activity
C1192_RS00535	COG2304	oxidoreductase activity
C1192_RS00545	COG2153	protein acetylation
C1192_RS00550	COG4575	ribosome binding
C1192_RS00555	COG1169	isochorismate synthase
C1192_RS00570	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C1192_RS00580	COG0318	PFAM AMP-dependent synthetase and ligase
C1192_RS00650	COG1414	Transcriptional regulator
C1192_RS00660	COG2271	Major facilitator Superfamily
C1192_RS00675	COG5464	transposase or invertase
C1192_RS00680	COG0247	lactate metabolic process
C1192_RS00690	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C1192_RS00695	COG2271	Major facilitator Superfamily
C1192_RS00700	COG0584	glycerophosphoryl diester phosphodiesterase
C1192_RS00705	COG3642	lipopolysaccharide core region biosynthetic process
C1192_RS00710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C1192_RS00715	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1192_RS00720	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1192_RS00740	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C1192_RS00745	COG4685	Uncharacterized protein conserved in bacteria (DUF2138)
C1192_RS00750	COG3234	Protein of unknown function (DUF1175)
C1192_RS00755	COG2373	Large extracellular alpha-helical protein
C1192_RS00760	COG5445	Predicted secreted protein (DUF2300)
C1192_RS00765	COG4676	Protein conserved in bacteria
C1192_RS00770	COG0183	Belongs to the thiolase family
C1192_RS00775	COG2031	fatty acid transporter
C1192_RS00780	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C1192_RS00785	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C1192_RS00790	COG2204	response regulator
C1192_RS00795	COG3852	Histidine kinase
C1192_RS00800	COG0784	Response regulator, receiver
C1192_RS00800	COG2205	protein histidine kinase activity
C1192_RS00805	COG2197	response regulator
C1192_RS00810	COG0642	Histidine kinase
C1192_RS00810	COG2198	Histidine kinase
C1192_RS00825	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C1192_RS00830	COG1477	protein flavinylation
C1192_RS00835	COG2169	Transcriptional regulator
C1192_RS00835	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C1192_RS00840	COG3145	DNA-N1-methyladenine dioxygenase activity
C1192_RS00845	COG4615	Cyclic peptide transporter
C1192_RS00860	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1192_RS00860	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1192_RS00865	COG3062	negative regulation of establishment of protein localization
C1192_RS00875	COG0437	4 iron, 4 sulfur cluster binding
C1192_RS00880	COG0348	domain, Protein
C1192_RS00885	COG3043	anaerobic respiration
C1192_RS00890	COG3005	denitrification pathway
C1192_RS00895	COG4133	protoheme IX ABC transporter activity
C1192_RS00900	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C1192_RS00905	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C1192_RS00910	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C1192_RS00920	COG1138	Cytochrome C-type biogenesis protein
C1192_RS00925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1192_RS00945	COG3083	sulfuric ester hydrolase activity
C1192_RS00965	COG1061	Type III restriction enzyme res subunit
C1192_RS00975	COG1187	pseudouridine synthase activity
C1192_RS00980	COG2814	Major facilitator Superfamily
C1192_RS00995	COG4172	Belongs to the ABC transporter superfamily
C1192_RS01000	COG4239	(ABC) transporter, permease
C1192_RS01005	COG4174	ABC transporter (Permease)
C1192_RS01010	COG4166	transmembrane transport
C1192_RS01015	COG2200	EAL domain
C1192_RS01020	COG0791	NLP P60 protein
C1192_RS01025	COG0671	phosphoesterase, PA-phosphatase related
C1192_RS01030	COG0523	cobalamin synthesis protein
C1192_RS01035	COG0246	Mannitol dehydrogenase
C1192_RS01040	COG3328	transposase activity
C1192_RS01045	COG0433	COG0433 Predicted ATPase
C1192_RS01050	COG1064	alcohol dehydrogenase
C1192_RS01060	COG3385	transposase activity
C1192_RS01075	COG2814	Major facilitator Superfamily
C1192_RS01080	COG2814	Major facilitator Superfamily
C1192_RS01085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1192_RS01085	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1192_RS01090	COG1105	Belongs to the carbohydrate kinase PfkB family
C1192_RS01095	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1192_RS01095	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C1192_RS01095	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1192_RS01100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1192_RS01105	COG2313	pseudouridylate synthase activity
C1192_RS01110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C1192_RS01115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1192_RS01125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C1192_RS01130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1192_RS01130	COG1522	sequence-specific DNA binding
C1192_RS01140	COG2855	membrane
C1192_RS01145	COG0583	DNA-binding transcription factor activity
C1192_RS01155	COG0833	amino acid
C1192_RS01165	COG4771	TonB-dependent receptor
C1192_RS01190	COG2311	Membrane
C1192_RS01200	COG1609	Transcriptional regulator
C1192_RS01205	COG1879	ABC-type sugar transport system periplasmic component
C1192_RS01210	COG1129	ABC transporter
C1192_RS01215	COG4211	Belongs to the binding-protein-dependent transport system permease family
C1192_RS01220	COG0167	dihydroorotate dehydrogenase activity
C1192_RS01220	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C1192_RS01225	COG0493	'glutamate synthase
C1192_RS01235	COG2949	membrane
C1192_RS01245	COG1346	cytolysis
C1192_RS01255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C1192_RS01275	COG0586	Pfam SNARE associated Golgi protein
C1192_RS01285	COG1686	Belongs to the peptidase S11 family
C1192_RS01290	COG0277	FAD linked oxidase domain protein
C1192_RS01295	COG1472	Belongs to the glycosyl hydrolase 3 family
C1192_RS01300	COG1732	Glycine betaine
C1192_RS01305	COG1174	glycine betaine transport
C1192_RS01310	COG1125	glycine betaine transport
C1192_RS01315	COG1174	glycine betaine transport
C1192_RS01325	COG0789	Transcriptional regulator
C1192_RS01330	COG3275	phosphorelay sensor kinase activity
C1192_RS01335	COG3279	Response regulator of the LytR AlgR family
C1192_RS01340	COG4807	Protein conserved in bacteria
C1192_RS01345	COG4808	Protein conserved in bacteria
C1192_RS01350	COG4715	Zinc finger, swim domain protein
C1192_RS01355	COG3552	Protein containing von Willebrand factor type A (VWA) domain
C1192_RS01360	COG2425	protein containing a von Willebrand factor type A (vWA) domain
C1192_RS01365	COG0714	Associated with various cellular activities
C1192_RS01375	COG3831	ATPase activity
C1192_RS01385	COG3831	ATPase activity
C1192_RS01400	COG0489	protein tyrosine kinase activity
C1192_RS01410	COG3539	Fimbrial protein
C1192_RS01415	COG3121	Chaperone
C1192_RS01420	COG3188	usher protein
C1192_RS01425	COG3539	Fimbrial protein
C1192_RS01430	COG5455	response to cobalt ion
C1192_RS01435	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
C1192_RS01450	COG0351	phosphomethylpyrimidine kinase
C1192_RS01455	COG3757	hydrolase, family 25
C1192_RS01460	COG2188	Transcriptional regulator
C1192_RS01465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1192_RS01470	COG1397	ADP-ribosylglycohydrolase
C1192_RS01475	COG2211	Major facilitator Superfamily
C1192_RS01480	COG1830	Aldolase
C1192_RS01490	COG0826	peptidase U32
C1192_RS01500	COG0745	RESPONSE REGULATOR receiver
C1192_RS01505	COG2205	protein histidine kinase activity
C1192_RS01535	COG3328	transposase activity
C1192_RS01545	COG4245	von Willebrand factor, type A
C1192_RS01550	COG0631	protein serine/threonine phosphatase activity
C1192_RS01555	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
C1192_RS01560	COG0443	Heat shock 70 kDa protein
C1192_RS01575	COG5002	protein histidine kinase activity
C1192_RS01575	COG3447	MASE1 domain protein
C1192_RS01575	COG5001	Diguanylate cyclase
C1192_RS01590	COG2982	Protein involved in outer membrane biogenesis
C1192_RS01595	COG1253	flavin adenine dinucleotide binding
C1192_RS01600	COG1596	polysaccharide export
C1192_RS01605	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C1192_RS01610	COG0489	protein tyrosine kinase activity
C1192_RS01610	COG3206	protein involved in exopolysaccharide biosynthesis
C1192_RS01615	COG0463	Glycosyl transferase, family 2
C1192_RS01620	COG1045	serine acetyltransferase
C1192_RS01625	COG0438	transferase activity, transferring glycosyl groups
C1192_RS01635	COG1216	Glycosyl transferase, family 2
C1192_RS01640	COG0110	maltose O-acetyltransferase activity
C1192_RS01645	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C1192_RS01650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C1192_RS01655	COG1051	belongs to the nudix hydrolase family
C1192_RS01660	COG0297	glycogen (starch) synthase activity
C1192_RS01665	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C1192_RS01665	COG0662	Cupin 2, conserved barrel domain protein
C1192_RS01670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C1192_RS01675	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C1192_RS01680	COG2244	polysaccharide biosynthetic process
C1192_RS01685	COG2327	Polysaccharide pyruvyl transferase
C1192_RS01690	COG0438	transferase activity, transferring glycosyl groups
C1192_RS01700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C1192_RS01705	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C1192_RS01730	COG1216	Glycosyl transferase, family 2
C1192_RS01730	COG0463	Glycosyl transferase, family 2
C1192_RS01750	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C1192_RS01760	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C1192_RS01780	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C1192_RS01785	COG0131	Imidazoleglycerol-phosphate dehydratase
C1192_RS01785	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C1192_RS01795	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C1192_RS01815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C1192_RS01820	COG0583	DNA-binding transcription factor activity
C1192_RS01830	COG0531	amino acid
C1192_RS01835	COG2925	Exonuclease
C1192_RS01840	COG1686	Belongs to the peptidase S11 family
C1192_RS01850	COG1289	transmembrane transporter activity
C1192_RS01875	COG4656	Part of a membrane complex involved in electron transport
C1192_RS01880	COG1012	belongs to the aldehyde dehydrogenase family
C1192_RS01880	COG1454	alcohol dehydrogenase
C1192_RS01895	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
C1192_RS01910	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C1192_RS01970	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
C1192_RS01985	COG1376	ErfK ybiS ycfS ynhG family protein
C1192_RS02000	COG0583	DNA-binding transcription factor activity
C1192_RS02025	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C1192_RS02030	COG0477	Major facilitator Superfamily
C1192_RS02070	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C1192_RS02080	COG1418	mRNA catabolic process
C1192_RS02085	COG0270	DNA (cytosine-5-)-methyltransferase activity
C1192_RS02090	COG3727	T/G mismatch-specific endonuclease activity
C1192_RS02095	COG0697	spore germination
C1192_RS02100	COG2354	Protein conserved in bacteria
C1192_RS02105	COG5475	Uncharacterized small protein (DUF2158)
C1192_RS02140	COG2197	response regulator
C1192_RS02145	COG1684	flagellar biosynthetic protein fliR
C1192_RS02150	COG1987	bacterial-type flagellum assembly
C1192_RS02155	COG1338	Plays a role in the flagellum-specific transport system
C1192_RS02160	COG3190	flagellar
C1192_RS02165	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C1192_RS02170	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C1192_RS02185	COG2882	bacterial-type flagellum organization
C1192_RS02190	COG1157	protein secretion by the type III secretion system
C1192_RS02195	COG1317	bacterial-type flagellum organization
C1192_RS02200	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C1192_RS02205	COG1766	The M ring may be actively involved in energy transduction
C1192_RS02210	COG3385	transposase activity
C1192_RS02225	COG5562	phage envelope protein
C1192_RS02230	COG3443	Belongs to the bacterial solute-binding protein 9 family
C1192_RS02235	COG0425	Belongs to the sulfur carrier protein TusA family
C1192_RS02240	COG2391	methyltransferase activity
C1192_RS02255	COG0366	Alpha amylase catalytic
C1192_RS02265	COG1516	flagellar protein fliS
C1192_RS02270	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C1192_RS02285	COG1191	sigma factor activity
C1192_RS02295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1192_RS02305	COG0765	amino acid transport
C1192_RS02310	COG1126	abc transporter atp-binding protein
C1192_RS02315	COG2197	response regulator
C1192_RS02325	COG2197	response regulator
C1192_RS02355	COG3012	SEC-C Motif Domain Protein
C1192_RS02355	COG3318	Belongs to the UPF0149 family
C1192_RS02360	COG0814	amino acid
C1192_RS02370	COG1528	Iron-storage protein
C1192_RS02395	COG1528	Iron-storage protein
C1192_RS02405	COG1879	ABC-type sugar transport system periplasmic component
C1192_RS02410	COG1129	ABC transporter
C1192_RS02415	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1192_RS02420	COG1877	trehalose-phosphatase activity
C1192_RS02430	COG0589	response to stress
C1192_RS02450	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C1192_RS02455	COG1360	Flagellar Motor Protein
C1192_RS02460	COG2198	Histidine kinase
C1192_RS02460	COG0643	Histidine kinase
C1192_RS02465	COG0835	chemotaxis
C1192_RS02470	COG0840	transmembrane signaling receptor activity
C1192_RS02475	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C1192_RS02485	COG0745	RESPONSE REGULATOR receiver
C1192_RS02490	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C1192_RS02495	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C1192_RS02520	COG3102	Protein conserved in bacteria
C1192_RS02540	COG3788	relative of glutathione S-transferase, MAPEG superfamily
C1192_RS02545	COG1801	Protein of unknown function DUF72
C1192_RS02550	COG0582	viral genome integration into host DNA
C1192_RS02615	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C1192_RS02655	COG1484	DNA-dependent DNA replication
C1192_RS02660	COG0305	Participates in initiation and elongation during chromosome replication
C1192_RS02670	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C1192_RS02705	COG4372	Transposase
C1192_RS02710	COG3436	PFAM IS66 Orf2 family protein
C1192_RS02780	COG4695	Portal protein
C1192_RS02820	COG4386	tail sheath protein
C1192_RS02860	COG3299	homolog of phage Mu protein gp47
C1192_RS02865	COG3778	Protein conserved in bacteria
C1192_RS02905	COG1335	isochorismatase
C1192_RS02920	COG0494	nUDIX hydrolase
C1192_RS02925	COG0217	transcriptional regulatory protein
C1192_RS02955	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C1192_RS02970	COG2719	SpoVR family
C1192_RS02980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C1192_RS02990	COG1619	proteins homologs of microcin C7 resistance protein MccF
C1192_RS03010	COG3385	transposase activity
C1192_RS03020	COG3436	PFAM IS66 Orf2 family protein
C1192_RS03025	COG4372	Transposase
C1192_RS03035	COG1388	LysM domain
C1192_RS03035	COG0741	lytic transglycosylase activity
C1192_RS03095	COG3436	PFAM IS66 Orf2 family protein
C1192_RS03100	COG4372	Transposase
C1192_RS03115	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C1192_RS03135	COG3008	intermembrane lipid transfer
C1192_RS03140	COG2995	paraquat-inducible protein a
C1192_RS03145	COG1956	GAF domain-containing protein
C1192_RS03155	COG0793	Belongs to the peptidase S41A family
C1192_RS03165	COG2814	Major facilitator Superfamily
C1192_RS03170	COG1414	Transcriptional regulator
C1192_RS03205	COG2226	methyltransferase
C1192_RS03225	COG3716	PTS system mannose fructose sorbose family IID component
C1192_RS03230	COG3715	PTS system
C1192_RS03235	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1192_RS03235	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1192_RS03250	COG1253	flavin adenine dinucleotide binding
C1192_RS03255	COG2200	EAL domain
C1192_RS03260	COG1760	l-serine dehydratase
C1192_RS03270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C1192_RS03290	COG0251	oxidation-reduction process
C1192_RS03295	COG1199	ATP-dependent helicase activity
C1192_RS03300	COG1214	PFAM Peptidase M22, glycoprotease
C1192_RS03305	COG3065	identical protein binding
C1192_RS03310	COG0318	PFAM AMP-dependent synthetase and ligase
C1192_RS03315	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C1192_RS03325	COG0583	DNA-binding transcription factor activity
C1192_RS03335	COG3615	Tellurite resistance protein tehB
C1192_RS03345	COG2261	transglycosylase associated protein
C1192_RS03360	COG2199	diguanylate cyclase activity
C1192_RS03360	COG2203	Gaf domain
C1192_RS03365	COG3042	response to heat
C1192_RS03370	COG3189	MarR family transcriptional regulator
C1192_RS03385	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C1192_RS03390	COG2199	diguanylate cyclase activity
C1192_RS03395	COG2199	diguanylate cyclase activity
C1192_RS03405	COG2766	serine protein kinase
C1192_RS03410	COG3713	MltA-interacting MipA family protein
C1192_RS03415	COG0656	L-ascorbic acid biosynthetic process
C1192_RS03420	COG0676	glucose-6-phosphate 1-epimerase activity
C1192_RS03425	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C1192_RS03435	COG3139	Protein of unknown function (DUF1315)
C1192_RS03440	COG1335	isochorismatase
C1192_RS03450	COG0252	asparaginase activity
C1192_RS03460	COG0616	signal peptide processing
C1192_RS03470	COG0778	Nitroreductase
C1192_RS03485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C1192_RS03490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C1192_RS03505	COG0494	nUDIX hydrolase
C1192_RS03510	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C1192_RS03515	COG2897	thiosulfate sulfurtransferase activity
C1192_RS03520	COG4136	ATPase activity
C1192_RS03525	COG4135	transport system, permease component
C1192_RS03530	COG4134	Bacterial extracellular solute-binding protein
C1192_RS03535	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C1192_RS03540	COG0398	Pfam SNARE associated Golgi protein
C1192_RS03550	COG0398	Pfam SNARE associated Golgi protein
C1192_RS03555	COG0708	Exodeoxyribonuclease III
C1192_RS03590	COG3678	ATP-independent chaperone mediated protein folding
C1192_RS03605	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1192_RS03610	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C1192_RS03615	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C1192_RS03620	COG1447	Phosphotransferase system cellobiose-specific component IIA
C1192_RS03625	COG2169	Transcriptional regulator
C1192_RS03625	COG1917	Cupin 2, conserved barrel domain protein
C1192_RS03630	COG1486	melibiose metabolic process
C1192_RS03635	COG3394	polysaccharide catabolic process
C1192_RS03640	COG0753	catalase activity
C1192_RS03650	COG1823	symporter activity
C1192_RS03655	COG1988	membrane-bound metal-dependent
C1192_RS03660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1192_RS03670	COG3001	Fructosamine kinase
C1192_RS03680	COG1105	Belongs to the carbohydrate kinase PfkB family
C1192_RS03685	COG3137	Salt-induced outer membrane protein
C1192_RS03740	COG0386	Belongs to the glutathione peroxidase family
C1192_RS03750	COG0791	NLP P60 protein
C1192_RS03755	COG2200	EAL domain
C1192_RS03765	COG4256	Hemin uptake protein
C1192_RS03770	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C1192_RS03780	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C1192_RS03780	COG0574	Belongs to the PEP-utilizing enzyme family
C1192_RS03785	COG4670	ketone body catabolic process
C1192_RS03815	COG0628	permease
C1192_RS03820	COG0247	lactate metabolic process
C1192_RS03820	COG0277	FAD linked oxidase domain protein
C1192_RS03825	COG2050	protein possibly involved in aromatic compounds catabolism
C1192_RS03835	COG0316	Belongs to the HesB IscA family
C1192_RS03840	COG0719	Fe-S assembly protein
C1192_RS03845	COG0396	ATPase activity
C1192_RS03850	COG0719	Fe-S assembly protein
C1192_RS03870	COG1376	ErfK ybiS ycfS ynhG family protein
C1192_RS03875	COG4238	major outer membrane lipoprotein
C1192_RS03880	COG0469	pyruvate kinase activity
C1192_RS03895	COG4529	Protein conserved in bacteria
C1192_RS03915	COG3468	outer membrane autotransporter barrel domain protein
C1192_RS03925	COG0307	riboflavin synthase, alpha
C1192_RS03930	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C1192_RS03935	COG2814	Major facilitator Superfamily
C1192_RS03940	COG0583	DNA-binding transcription factor activity
C1192_RS03960	COG2814	Major facilitator Superfamily
C1192_RS03965	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C1192_RS03970	COG0791	NLP P60 protein
C1192_RS03975	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C1192_RS03980	COG1201	RNA secondary structure unwinding
C1192_RS03980	COG1201	RNA secondary structure unwinding
C1192_RS03990	COG0346	lactoylglutathione lyase activity
C1192_RS03995	COG1902	pentaerythritol trinitrate reductase activity
C1192_RS04000	COG1309	transcriptional regulator
C1192_RS04005	COG3313	Fe-S protein
C1192_RS04010	COG4989	oxidoreductase activity
C1192_RS04015	COG2032	superoxide dismutase activity
C1192_RS04025	COG1566	PFAM secretion protein HlyD family protein
C1192_RS04040	COG3133	Outer membrane lipoprotein
C1192_RS04050	COG3895	Periplasmic Protein
C1192_RS04065	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C1192_RS04070	COG0625	glutathione transferase activity
C1192_RS04075	COG3104	oligopeptide transport
C1192_RS04085	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C1192_RS04095	COG4659	FMN binding
C1192_RS04140	COG0673	inositol 2-dehydrogenase activity
C1192_RS04150	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C1192_RS04155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1192_RS04155	COG1263	PTS System
C1192_RS04160	COG1609	Transcriptional regulator
C1192_RS04165	COG1028	Short-chain dehydrogenase reductase Sdr
C1192_RS04170	COG1309	transcriptional regulator
C1192_RS04175	COG3250	beta-galactosidase activity
C1192_RS04190	COG5339	Protein conserved in bacteria
C1192_RS04195	COG1482	cell wall glycoprotein biosynthetic process
C1192_RS04200	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C1192_RS04200	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C1192_RS04205	COG0114	fumarate hydratase activity
C1192_RS04225	COG3136	membrane protein required for alginate biosynthesis
C1192_RS04235	COG0531	amino acid
C1192_RS04250	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C1192_RS04255	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C1192_RS04260	COG0628	permease
C1192_RS04280	COG3591	Belongs to the peptidase S1B family
C1192_RS04300	COG0583	DNA-binding transcription factor activity
C1192_RS04305	COG1940	carbohydrate kinase activity
C1192_RS04310	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C1192_RS04320	COG3381	protein complex oligomerization
C1192_RS04325	COG3302	dmso reductase anchor subunit
C1192_RS04330	COG0437	4 iron, 4 sulfur cluster binding
C1192_RS04350	COG3328	transposase activity
C1192_RS04355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1192_RS04370	COG4948	Mandelate Racemase Muconate Lactonizing
C1192_RS04375	COG1063	alcohol dehydrogenase
C1192_RS04385	COG0582	viral genome integration into host DNA
C1192_RS04395	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C1192_RS04425	COG1396	sequence-specific DNA binding
C1192_RS04440	COG1846	Transcriptional regulator
C1192_RS04455	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C1192_RS04480	COG3385	transposase activity
C1192_RS04490	COG3436	PFAM IS66 Orf2 family protein
C1192_RS04495	COG4372	Transposase
C1192_RS04510	COG1403	HNH endonuclease
C1192_RS04515	COG0484	heat shock protein binding
C1192_RS04525	COG1278	Cold shock
C1192_RS04530	COG1278	Cold shock
C1192_RS04550	COG3772	lysozyme
C1192_RS04560	COG1278	Cold shock
C1192_RS04610	COG0740	serine-type endopeptidase activity
C1192_RS04680	COG3328	transposase activity
C1192_RS04685	COG2015	COG2015, Alkyl sulfatase and related hydrolases
C1192_RS04695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C1192_RS04700	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C1192_RS04705	COG0384	phenazine biosynthesis protein PhzF
C1192_RS04710	COG2181	nitrate reductase activity
C1192_RS04715	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C1192_RS04720	COG1140	nitrate reductase beta subunit
C1192_RS04725	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C1192_RS04730	COG2223	nitrite transmembrane transporter activity
C1192_RS04735	COG0697	spore germination
C1192_RS04740	COG0243	molybdopterin cofactor binding
C1192_RS04740	COG3383	formate dehydrogenase (NAD+) activity
C1192_RS04745	COG3383	formate dehydrogenase (NAD+) activity
C1192_RS04745	COG0243	molybdopterin cofactor binding
C1192_RS04750	COG0437	4 iron, 4 sulfur cluster binding
C1192_RS04755	COG2864	formate dehydrogenase
C1192_RS04760	COG3093	addiction module antidote protein HigA
C1192_RS04775	COG1064	alcohol dehydrogenase
C1192_RS04795	COG1764	response to oxidative stress
C1192_RS04815	COG1649	PFAM Uncharacterised BCR, COG1649
C1192_RS04820	COG0531	amino acid
C1192_RS04825	COG0076	glutamate decarboxylase activity
C1192_RS04835	COG4771	TonB-dependent receptor
C1192_RS04845	COG0641	radical SAM
C1192_RS04850	COG3119	arylsulfatase activity
C1192_RS04885	COG3781	membrane
C1192_RS04900	COG2199	diguanylate cyclase activity
C1192_RS04915	COG2066	Belongs to the glutaminase family
C1192_RS04920	COG1012	belongs to the aldehyde dehydrogenase family
C1192_RS04925	COG0583	DNA-binding transcription factor activity
C1192_RS04940	COG1846	Transcriptional regulator
C1192_RS04945	COG4977	sequence-specific DNA binding
C1192_RS04955	COG0697	spore germination
C1192_RS04960	COG2814	Major facilitator Superfamily
C1192_RS04975	COG3706	GGDEF domain
C1192_RS04980	COG0339	signal peptide processing
C1192_RS04985	COG4221	oxidoreductase activity
C1192_RS04990	COG1802	Transcriptional regulator
C1192_RS05000	COG0246	Mannitol dehydrogenase
C1192_RS05005	COG0477	Major facilitator Superfamily
C1192_RS05015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C1192_RS05020	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C1192_RS05025	COG5301	cellulose 1,4-beta-cellobiosidase activity
C1192_RS05035	COG3385	transposase activity
C1192_RS05040	COG3328	transposase activity
C1192_RS05045	COG3706	GGDEF domain
C1192_RS05045	COG2203	Gaf domain
C1192_RS05045	COG5001	Diguanylate cyclase
C1192_RS05045	COG4251	negative regulation of phosphorylation
C1192_RS05065	COG3385	transposase activity
C1192_RS05075	COG3436	PFAM IS66 Orf2 family protein
C1192_RS05080	COG4372	Transposase
C1192_RS05125	COG1113	amino acid transport
C1192_RS05140	COG4772	TonB-dependent receptor
C1192_RS05150	COG1247	-acetyltransferase
C1192_RS05155	COG3238	Protein conserved in bacteria
C1192_RS05180	COG1177	transmembrane transport
C1192_RS05185	COG1176	ABC-type spermidine putrescine transport system, permease component I
C1192_RS05190	COG3842	ATPase activity
C1192_RS05195	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C1192_RS05200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1192_RS05205	COG1598	PFAM Uncharacterised protein family UPF0150
C1192_RS05210	COG1724	mRNA binding
C1192_RS05220	COG0826	peptidase U32
C1192_RS05225	COG1396	sequence-specific DNA binding
C1192_RS05230	COG3135	benzoate transporter
C1192_RS05240	COG0500	methyltransferase
C1192_RS05245	COG1275	C4-dicarboxylate transporter malic acid transport protein
C1192_RS05250	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C1192_RS05255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1192_RS05260	COG2841	Protein conserved in bacteria
C1192_RS05280	COG5383	Protein conserved in bacteria
C1192_RS05285	COG0583	DNA-binding transcription factor activity
C1192_RS05290	COG0840	transmembrane signaling receptor activity
C1192_RS05315	COG1012	belongs to the aldehyde dehydrogenase family
C1192_RS05320	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C1192_RS05335	COG3436	PFAM IS66 Orf2 family protein
C1192_RS05340	COG4372	Transposase
C1192_RS05345	COG1643	Atp-dependent helicase
C1192_RS05355	COG0667	Aldo Keto reductase
C1192_RS05365	COG3784	Protein of unknown function (DUF1318)
C1192_RS05375	COG2911	Protein conserved in bacteria
C1192_RS05380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C1192_RS05385	COG3187	Heat shock protein
C1192_RS05390	COG3042	response to heat
C1192_RS05395	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C1192_RS05395	COG1013	pyruvate-flavodoxin oxidoreductase activity
C1192_RS05395	COG0674	pyruvate-flavodoxin oxidoreductase activity
C1192_RS05395	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C1192_RS05415	COG0589	response to stress
C1192_RS05425	COG0513	Belongs to the DEAD box helicase family
C1192_RS05445	COG2840	Smr protein MutS2
C1192_RS05450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C1192_RS05455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1192_RS05460	COG0589	response to stress
C1192_RS05465	COG3182	Iron-regulated membrane protein
C1192_RS05470	COG0668	transmembrane transport
C1192_RS05485	COG4166	transmembrane transport
C1192_RS05490	COG2866	Carboxypeptidase
C1192_RS05495	COG4948	Mandelate Racemase Muconate Lactonizing
C1192_RS05500	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C1192_RS05505	COG3283	Transcriptional regulator of aromatic amino acids metabolism
C1192_RS05515	COG3106	COG3106 Predicted ATPase
C1192_RS05520	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1192_RS05530	COG1983	PspC domain protein
C1192_RS05540	COG1842	Phage shock protein A
C1192_RS05545	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C1192_RS05560	COG4166	transmembrane transport
C1192_RS05565	COG4168	peptide transport system, permease
C1192_RS05570	COG4171	peptide transport system, permease
C1192_RS05575	COG4172	Belongs to the ABC transporter superfamily
C1192_RS05580	COG4172	Belongs to the ABC transporter superfamily
C1192_RS05585	COG2814	Major facilitator Superfamily
C1192_RS05600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1192_RS05610	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C1192_RS05615	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C1192_RS05615	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C1192_RS05630	COG5001	Diguanylate cyclase
C1192_RS05640	COG1349	DNA-binding transcription factor activity
C1192_RS05650	COG0023	Translation Initiation Factor
C1192_RS05660	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C1192_RS05665	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
C1192_RS05670	COG0671	phosphoesterase, PA-phosphatase related
C1192_RS05680	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C1192_RS05690	COG3344	reverse transcriptase
C1192_RS05705	COG0583	DNA-binding transcription factor activity
C1192_RS05715	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C1192_RS05730	COG3328	transposase activity
C1192_RS05735	COG0616	signal peptide processing
C1192_RS05740	COG1028	Short-chain dehydrogenase reductase Sdr
C1192_RS05745	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C1192_RS05760	COG1187	pseudouridine synthase activity
C1192_RS05770	COG0009	L-threonylcarbamoyladenylate synthase
C1192_RS05775	COG0613	PHP domain protein
C1192_RS05785	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C1192_RS05790	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C1192_RS05790	COG0512	Glutamine amidotransferase of anthranilate synthase
C1192_RS05795	COG0134	indole-3-glycerol-phosphate synthase activity
C1192_RS05795	COG0135	phosphoribosylanthranilate isomerase activity
C1192_RS05810	COG3047	cAMP biosynthetic process
C1192_RS05825	COG1607	acyl-coa hydrolase
C1192_RS05830	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C1192_RS05835	COG2350	Protein conserved in bacteria
C1192_RS05840	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C1192_RS05860	COG4608	Belongs to the ABC transporter superfamily
C1192_RS05865	COG0444	Belongs to the ABC transporter superfamily
C1192_RS05870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1192_RS05875	COG0601	transmembrane transport
C1192_RS05880	COG4166	transmembrane transport
C1192_RS05890	COG2095	MarC family integral membrane protein
C1192_RS05895	COG1012	belongs to the aldehyde dehydrogenase family
C1192_RS05895	COG1454	alcohol dehydrogenase
C1192_RS05900	COG3328	transposase activity
C1192_RS05910	COG1435	thymidine kinase activity
C1192_RS05920	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C1192_RS05925	COG0745	RESPONSE REGULATOR receiver
C1192_RS05930	COG1752	Esterase of the alpha-beta hydrolase superfamily
C1192_RS05940	COG0788	formyltetrahydrofolate deformylase activity
C1192_RS05975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C1192_RS05980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C1192_RS05985	COG2181	nitrate reductase activity
C1192_RS05990	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C1192_RS05995	COG1140	nitrate reductase beta subunit
C1192_RS06000	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C1192_RS06005	COG2223	nitrite transmembrane transporter activity
C1192_RS06015	COG3850	Histidine kinase
C1192_RS06020	COG2197	response regulator
C1192_RS06025	COG4932	domain protein
C1192_RS06030	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C1192_RS06035	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C1192_RS06040	COG4572	Cation transport regulator
C1192_RS06045	COG0387	Pfam Sodium calcium exchanger
C1192_RS06060	COG2912	Transglutaminase-like superfamily
C1192_RS06065	COG3094	Invasion gene expression up-regulator, SirB
C1192_RS06070	COG2890	protein-(glutamine-N5) methyltransferase activity
C1192_RS06100	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C1192_RS06110	COG0659	secondary active sulfate transmembrane transporter activity
C1192_RS06125	COG0012	GTP binding
C1192_RS06135	COG3284	Transcriptional regulator
C1192_RS06140	COG2376	Dihydroxyacetone kinase
C1192_RS06145	COG1461	Dihydroxyacetone kinase
C1192_RS06150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1192_RS06150	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C1192_RS06150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C1192_RS06165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1192_RS06170	COG1120	ATPase activity
C1192_RS06175	COG0500	methyltransferase
C1192_RS06180	COG0157	Belongs to the NadC ModD family
C1192_RS06200	COG4372	Transposase
C1192_RS06205	COG3436	PFAM IS66 Orf2 family protein
C1192_RS06215	COG3385	transposase activity
C1192_RS06275	COG0582	viral genome integration into host DNA
C1192_RS06285	COG1276	copper resistance
C1192_RS06290	COG2372	response to copper ion
C1192_RS06300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1192_RS06305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C1192_RS06310	COG1770	oligopeptidase
C1192_RS06315	COG2979	Protein of unknown function (DUF533)
C1192_RS06325	COG3141	response to X-ray
C1192_RS06335	COG0800	Aldolase
C1192_RS06340	COG0129	dihydroxy-acid dehydratase activity
C1192_RS06345	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C1192_RS06355	COG1737	Transcriptional regulator
C1192_RS06360	COG0469	pyruvate kinase activity
C1192_RS06365	COG3385	transposase activity
C1192_RS06370	COG1560	Kdo2-lipid A biosynthetic process
C1192_RS06375	COG0739	heme binding
C1192_RS06380	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C1192_RS06390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C1192_RS06400	COG0179	Fumarylacetoacetate (FAA) hydrolase
C1192_RS06415	COG2894	cell division
C1192_RS06440	COG2200	EAL domain
C1192_RS06450	COG0727	PFAM Uncharacterised protein family (UPF0153)
C1192_RS06455	COG0217	transcriptional regulatory protein
C1192_RS06470	COG1902	pentaerythritol trinitrate reductase activity
C1192_RS06485	COG1278	Cold shock
C1192_RS06500	COG1881	PFAM PEBP family protein
C1192_RS06510	COG2076	Multidrug Resistance protein
C1192_RS06525	COG3436	PFAM IS66 Orf2 family protein
C1192_RS06530	COG4372	Transposase
C1192_RS06555	COG0538	isocitrate dehydrogenase activity
C1192_RS06560	COG1187	pseudouridine synthase activity
C1192_RS06580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C1192_RS06590	COG2205	protein histidine kinase activity
C1192_RS06595	COG2850	peptidyl-arginine hydroxylation
C1192_RS06610	COG3842	ATPase activity
C1192_RS06620	COG1177	transmembrane transport
C1192_RS06625	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C1192_RS06635	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C1192_RS06640	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C1192_RS06650	COG4591	ABC-type transport system involved in lipoprotein release permease component
C1192_RS06660	COG4591	ABC-type transport system involved in lipoprotein release permease component
C1192_RS06665	COG4763	Acyl-transferase
C1192_RS06670	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C1192_RS06675	COG1376	ErfK ybiS ycfS ynhG family protein
C1192_RS06675	COG1388	LysM domain
C1192_RS06685	COG1309	transcriptional regulator
C1192_RS06690	COG3134	Outer membrane lipoprotein
C1192_RS06695	COG1252	NADH dehydrogenase
C1192_RS06710	COG0510	thiamine kinase activity
C1192_RS06715	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
C1192_RS06720	COG5633	Lipoprotein
C1192_RS06725	COG0537	adenosine 5'-monophosphoramidase activity
C1192_RS06735	COG1263	PTS System
C1192_RS06735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1192_RS06740	COG0084	hydrolase, TatD family'
C1192_RS06745	COG0470	DNA polymerase III
C1192_RS06755	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C1192_RS06760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C1192_RS06770	COG3121	Chaperone
C1192_RS06795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C1192_RS06805	COG1028	Short-chain dehydrogenase reductase Sdr
C1192_RS06810	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C1192_RS06830	COG1399	metal-binding, possibly nucleic acid-binding protein
C1192_RS06835	COG0424	maF-like protein
C1192_RS06840	COG0564	pseudouridine synthase activity
C1192_RS06850	COG1530	ribonuclease E activity
C1192_RS06855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1192_RS06860	COG1256	bacterial-type flagellum assembly
C1192_RS06865	COG1705	Flagellar rod assembly protein muramidase FlgJ
C1192_RS06865	COG3951	Flagellar rod assembly protein muramidase FlgJ
C1192_RS06880	COG4786	Flagellar basal body rod
C1192_RS06885	COG4787	bacterial-type flagellum-dependent cell motility
C1192_RS06895	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C1192_RS06900	COG1558	bacterial-type flagellum-dependent cell motility
C1192_RS06905	COG1815	bacterial-type flagellum-dependent cell motility
C1192_RS06915	COG2747	anti-sigma28 factor FlgM
C1192_RS06920	COG3418	PFAM FlgN family protein
C1192_RS06925	COG0728	peptidoglycan biosynthetic process
C1192_RS06930	COG0673	inositol 2-dehydrogenase activity
C1192_RS06940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1192_RS06985	COG3038	cytochrome b561
C1192_RS06990	COG2353	YceI-like domain
C1192_RS07000	COG1560	Kdo2-lipid A biosynthetic process
C1192_RS07020	COG3328	transposase activity
C1192_RS07030	COG3385	transposase activity
C1192_RS07035	COG2943	transferase activity, transferring hexosyl groups
C1192_RS07060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1192_RS07065	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C1192_RS07095	COG2197	response regulator
C1192_RS07110	COG1462	curli production assembly transport component CsgG
C1192_RS07120	COG3381	protein complex oligomerization
C1192_RS07145	COG1702	phosphate starvation-inducible protein PhoH
C1192_RS07155	COG2822	iron ion transport
C1192_RS07165	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C1192_RS07175	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C1192_RS07175	COG0506	proline dehydrogenase activity
C1192_RS07175	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C1192_RS07180	COG1309	transcriptional regulator
C1192_RS07185	COG3729	General stress protein
C1192_RS07215	COG0583	DNA-binding transcription factor activity
C1192_RS07245	COG0243	molybdopterin cofactor binding
C1192_RS07250	COG3005	denitrification pathway
C1192_RS07255	COG0745	RESPONSE REGULATOR receiver
C1192_RS07260	COG0784	Response regulator, receiver
C1192_RS07260	COG2198	Histidine kinase
C1192_RS07260	COG2205	protein histidine kinase activity
C1192_RS07265	COG0348	domain, Protein
C1192_RS07280	COG1278	Cold shock
C1192_RS07285	COG1278	Cold shock
C1192_RS07305	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1192_RS07310	COG1596	polysaccharide export
C1192_RS07315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C1192_RS07335	COG1294	oxidase, subunit
C1192_RS07340	COG1271	oxidase subunit
C1192_RS07345	COG1773	rubredoxin
C1192_RS07350	COG1999	signal sequence binding
C1192_RS07355	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C1192_RS07360	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
C1192_RS07365	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C1192_RS07370	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C1192_RS07385	COG0670	Belongs to the BI1 family
C1192_RS07390	COG2920	part of a sulfur-relay system
C1192_RS07395	COG1254	Belongs to the acylphosphatase family
C1192_RS07410	COG1832	CoA-binding protein
C1192_RS07425	COG0210	DNA helicase
C1192_RS07430	COG3304	Inner membrane component domain
C1192_RS07435	COG1289	transmembrane transporter activity
C1192_RS07440	COG3070	regulator of competence-specific genes
C1192_RS07460	COG1067	ATP-dependent peptidase activity
C1192_RS07470	COG3130	regulation of translation
C1192_RS07475	COG3009	Protein conserved in bacteria
C1192_RS07480	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C1192_RS07480	COG3008	intermembrane lipid transfer
C1192_RS07485	COG2995	paraquat-inducible protein a
C1192_RS07490	COG0488	(ABC) transporter
C1192_RS07500	COG3217	Mosc domain protein beta barrel domain protein
C1192_RS07500	COG0633	Ferredoxin
C1192_RS07520	COG0431	NADPH-dependent FMN reductase
C1192_RS07525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C1192_RS07535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1192_RS07545	COG0308	aminopeptidase N
C1192_RS07575	COG1448	Aminotransferase
C1192_RS07580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C1192_RS07585	COG3108	Peptidase M15
C1192_RS07590	COG2989	Protein conserved in bacteria
C1192_RS07595	COG3385	transposase activity
C1192_RS07605	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C1192_RS07615	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C1192_RS07620	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C1192_RS07625	COG3173	Aminoglycoside phosphotransferase
C1192_RS07640	COG3214	Protein conserved in bacteria
C1192_RS07655	COG2333	competence protein COMEC
C1192_RS07655	COG0658	competence protein
C1192_RS07665	COG0539	negative regulation of cytoplasmic translation
C1192_RS07675	COG0501	Belongs to the peptidase M48B family
C1192_RS07690	COG2323	membrane
C1192_RS07695	COG1944	ATP diphosphatase activity
C1192_RS07700	COG2116	formate transmembrane transporter activity
C1192_RS07705	COG1882	Formate acetyltransferase
C1192_RS07710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C1192_RS07715	COG3118	belongs to the thioredoxin family
C1192_RS07715	COG0457	Tetratricopeptide repeat
C1192_RS07720	COG1215	transferase activity, transferring glycosyl groups
C1192_RS07730	COG2199	diguanylate cyclase activity
C1192_RS07745	COG1335	isochorismatase
C1192_RS07750	COG3344	reverse transcriptase
C1192_RS07755	COG3302	dmso reductase anchor subunit
C1192_RS07760	COG0437	4 iron, 4 sulfur cluster binding
C1192_RS07765	COG0243	molybdopterin cofactor binding
C1192_RS07775	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C1192_RS07785	COG1674	ftsk spoiiie
C1192_RS07785	COG1178	ABC-type Fe3 transport system permease component
C1192_RS07790	COG1522	sequence-specific DNA binding
C1192_RS07800	COG0492	ferredoxin-NADP+ reductase activity
C1192_RS07805	COG4988	ABC transporter
C1192_RS07810	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C1192_RS07845	COG3539	Fimbrial protein
C1192_RS07875	COG1203	CRISPR-associated helicase, Cas3
C1192_RS07880	COG1518	maintenance of DNA repeat elements
C1192_RS07885	COG0542	response to heat
C1192_RS07895	COG1278	Cold shock
C1192_RS07905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1192_RS07910	COG2990	Protein conserved in bacteria
C1192_RS07915	COG3593	DNA synthesis involved in DNA repair
C1192_RS07925	COG2431	L-lysine efflux transmembrane transporter activity
C1192_RS07935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C1192_RS07940	COG0028	Belongs to the TPP enzyme family
C1192_RS07945	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C1192_RS07950	COG0702	epimerase
C1192_RS07955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C1192_RS07960	COG3023	N-Acetylmuramoyl-L-alanine amidase
C1192_RS07975	COG1126	abc transporter atp-binding protein
C1192_RS07980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1192_RS07985	COG4215	(ABC) transporter
C1192_RS07990	COG4160	amino acid transport
C1192_RS07995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1192_RS08010	COG1177	transmembrane transport
C1192_RS08015	COG1176	ABC-type spermidine putrescine transport system, permease component I
C1192_RS08020	COG3842	ATPase activity
C1192_RS08025	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C1192_RS08045	COG0778	Nitroreductase
C1192_RS08055	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C1192_RS08070	COG3226	Transcriptional regulator
C1192_RS08075	COG0738	Major facilitator superfamily
C1192_RS08080	COG0561	phosphatase activity
C1192_RS08090	COG2814	Major facilitator Superfamily
C1192_RS08095	COG0671	phosphoesterase, PA-phosphatase related
C1192_RS08100	COG1349	DNA-binding transcription factor activity
C1192_RS08105	COG1686	Belongs to the peptidase S11 family
C1192_RS08110	COG0625	glutathione transferase activity
C1192_RS08115	COG2133	pyrroloquinoline quinone binding
C1192_RS08125	COG1874	Beta-galactosidase
C1192_RS08130	COG1609	Transcriptional regulator
C1192_RS08135	COG2211	Major facilitator Superfamily
C1192_RS08145	COG2199	diguanylate cyclase activity
C1192_RS08150	COG2200	EAL domain
C1192_RS08165	COG0747	negative chemotaxis
C1192_RS08175	COG1446	asparaginase
C1192_RS08180	COG0303	'Molybdopterin
C1192_RS08185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C1192_RS08190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C1192_RS08195	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C1192_RS08200	COG1882	Formate acetyltransferase
C1192_RS08205	COG0561	phosphatase activity
C1192_RS08215	COG0488	(ABC) transporter
C1192_RS08220	COG1376	ErfK ybiS ycfS ynhG family protein
C1192_RS08225	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C1192_RS08230	COG1321	iron dependent repressor
C1192_RS08240	COG2194	sulfuric ester hydrolase activity
C1192_RS08245	COG3385	transposase activity
C1192_RS08250	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C1192_RS08255	COG5006	permease, DMT superfamily
C1192_RS08270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1192_RS08275	COG0765	amino acid transport
C1192_RS08280	COG1126	abc transporter atp-binding protein
C1192_RS08285	COG0668	transmembrane transport
C1192_RS08300	COG4774	siderophore transport
C1192_RS08310	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C1192_RS08320	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C1192_RS08325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C1192_RS08330	COG1199	ATP-dependent helicase activity
C1192_RS08340	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
C1192_RS08345	COG0513	Belongs to the DEAD box helicase family
C1192_RS08350	COG1309	transcriptional regulator
C1192_RS08360	COG1131	(ABC) transporter
C1192_RS08365	COG0842	Transport permease protein
C1192_RS08370	COG0842	Transport permease protein
C1192_RS08380	COG3568	Endonuclease Exonuclease Phosphatase
C1192_RS08385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1192_RS08390	COG0392	lysyltransferase activity
C1192_RS08400	COG0670	Belongs to the BI1 family
C1192_RS08405	COG0314	molybdopterin synthase activity
C1192_RS08410	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C1192_RS08420	COG0521	Mo-molybdopterin cofactor biosynthetic process
C1192_RS08430	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C1192_RS08440	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C1192_RS08445	COG2226	methyltransferase
C1192_RS08460	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C1192_RS08465	COG1881	PFAM PEBP family protein
C1192_RS08470	COG4677	pectinesterase activity
C1192_RS08480	COG0471	metal ion transport
C1192_RS08485	COG2828	Protein conserved in bacteria
C1192_RS08490	COG0583	DNA-binding transcription factor activity
C1192_RS08500	COG0561	phosphatase activity
C1192_RS08510	COG4149	molybdate abc transporter
C1192_RS08515	COG0725	ABC transporter, periplasmic molybdate-binding protein
C1192_RS08520	COG3328	transposase activity
C1192_RS08525	COG3344	reverse transcriptase
C1192_RS08535	COG3585	molybdate ion transport
C1192_RS08535	COG2005	Transcriptional regulator
C1192_RS08540	COG1119	ATPase activity
C1192_RS08545	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C1192_RS08550	COG1085	galactose-1-phosphate uridylyltransferase
C1192_RS08560	COG2017	converts alpha-aldose to the beta-anomer
C1192_RS08570	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C1192_RS08585	COG1230	cation diffusion facilitator family transporter
C1192_RS08590	COG3201	nicotinamide mononucleotide transporter
C1192_RS08630	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C1192_RS08635	COG2885	chlorophyll binding
C1192_RS08645	COG3064	Membrane
C1192_RS08650	COG0848	biopolymer transport protein
C1192_RS08655	COG0811	peptide transport
C1192_RS08660	COG0824	Thioesterase
C1192_RS08665	COG3790	cyd operon protein YbgE
C1192_RS08670	COG4890	Cyd operon protein YbgT
C1192_RS08675	COG1294	oxidase, subunit
C1192_RS08680	COG1271	oxidase subunit
C1192_RS08685	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C1192_RS08695	COG4865	methylaspartate mutase activity
C1192_RS08700	COG3799	methylaspartate ammonia-lyase activity
C1192_RS08715	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C1192_RS08715	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C1192_RS08720	COG0583	DNA-binding transcription factor activity
C1192_RS08735	COG3423	Transcriptional regulator
C1192_RS08745	COG2801	Transposase and inactivated derivatives
C1192_RS08750	COG2842	Transposition protein
C1192_RS08780	COG4396	Host-nuclease inhibitor protein Gam
C1192_RS08830	COG5566	PFAM Mor transcription activator
C1192_RS08860	COG0640	Transcriptional regulator
C1192_RS08870	COG4373	Mu-like prophage FluMu protein gp28
C1192_RS08875	COG4383	Mu-like prophage protein gp29
C1192_RS08880	COG2369	cell adhesion
C1192_RS08885	COG5005	Phage virion morphogenesis
C1192_RS08890	COG4388	Caudovirus prohead serine protease
C1192_RS08895	COG4397	Mu-like prophage major head subunit gpT
C1192_RS08920	COG4386	tail sheath protein
C1192_RS08930	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
C1192_RS08940	COG4228	DNA circulation
C1192_RS08950	COG4384	Bacteriophage Mu Gp45 protein
C1192_RS08955	COG4381	Mu-like prophage protein gp46
C1192_RS08960	COG3299	homolog of phage Mu protein gp47
C1192_RS08970	COG5301	cellulose 1,4-beta-cellobiosidase activity
C1192_RS08980	COG3328	transposase activity
C1192_RS08995	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C1192_RS09020	COG1228	amidohydrolase
C1192_RS09030	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C1192_RS09035	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C1192_RS09045	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C1192_RS09065	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1192_RS09070	COG0567	Dehydrogenase, E1 component
C1192_RS09075	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C1192_RS09080	COG1053	succinate dehydrogenase
C1192_RS09085	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C1192_RS09090	COG2009	succinate dehydrogenase
C1192_RS09105	COG0372	Belongs to the citrate synthase family
C1192_RS09110	COG3539	Fimbrial protein
C1192_RS09120	COG3121	Chaperone
C1192_RS09125	COG3539	Fimbrial protein
C1192_RS09130	COG3180	Ammonia monooxygenase
C1192_RS09145	COG1984	allophanate hydrolase subunit 2
C1192_RS09150	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C1192_RS09155	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C1192_RS09165	COG0415	Belongs to the DNA photolyase family
C1192_RS09170	COG3272	Protein of unknown function (DUF1722)
C1192_RS09185	COG4372	Transposase
C1192_RS09190	COG3436	PFAM IS66 Orf2 family protein
C1192_RS09265	COG2205	protein histidine kinase activity
C1192_RS09270	COG0745	RESPONSE REGULATOR receiver
C1192_RS09275	COG0033	Phosphoglucomutase
C1192_RS09280	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
C1192_RS09285	COG0596	Alpha beta hydrolase
C1192_RS09295	COG0716	FMN binding
C1192_RS09305	COG0735	belongs to the Fur family
C1192_RS09325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1192_RS09325	COG1263	PTS System
C1192_RS09325	COG2190	(PTS) system
C1192_RS09335	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C1192_RS09340	COG1940	carbohydrate kinase activity
C1192_RS09340	COG1846	Transcriptional regulator
C1192_RS09345	COG0647	UMP catabolic process
C1192_RS09355	COG0367	asparagine synthase
C1192_RS09405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1192_RS09415	COG1702	phosphate starvation-inducible protein PhoH
C1192_RS09425	COG4535	Mg2 and Co2 transporter CorC
C1192_RS09430	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C1192_RS09435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1192_RS09440	COG0765	amino acid transport
C1192_RS09445	COG0765	amino acid transport
C1192_RS09450	COG1126	abc transporter atp-binding protein
C1192_RS09455	COG3328	transposase activity
C1192_RS09460	COG3385	transposase activity
C1192_RS09470	COG0443	Heat shock 70 kDa protein
C1192_RS09475	COG2214	Heat shock protein DnaJ domain protein
C1192_RS09485	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C1192_RS09495	COG2888	peptidyl-tyrosine sulfation
C1192_RS09510	COG1466	dna polymerase III delta subunit
C1192_RS09520	COG0406	alpha-ribazole phosphatase activity
C1192_RS09525	COG0799	negative regulation of ribosome biogenesis
C1192_RS09535	COG0768	penicillin binding
C1192_RS09540	COG0772	Belongs to the SEDS family
C1192_RS09545	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C1192_RS09550	COG1686	Belongs to the peptidase S11 family
C1192_RS09575	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C1192_RS09580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1192_RS09605	COG3069	C4-dicarboxylate transmembrane transporter activity
C1192_RS09610	COG4565	transcriptional regulatory protein
C1192_RS09615	COG3290	protein histidine kinase activity
C1192_RS09625	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
C1192_RS09635	COG2301	Belongs to the HpcH HpaI aldolase family
C1192_RS09640	COG3051	citrate lyase alpha subunit
C1192_RS09655	COG0471	metal ion transport
C1192_RS09660	COG3719	Belongs to the RNase T2 family
C1192_RS09670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C1192_RS09675	COG0589	response to stress
C1192_RS09680	COG3634	alkyl hydroperoxide reductase activity
C1192_RS09685	COG0450	alkyl hydroperoxide reductase
C1192_RS09690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C1192_RS09695	COG0583	DNA-binding transcription factor activity
C1192_RS09700	COG3969	phosphoadenosine phosphosulfate
C1192_RS09705	COG1475	DNA binding
C1192_RS09710	COG0436	Aminotransferase
C1192_RS09715	COG0371	Dehydrogenase
C1192_RS09720	COG2879	small protein
C1192_RS09725	COG1966	Carbon starvation protein
C1192_RS09730	COG2050	protein possibly involved in aromatic compounds catabolism
C1192_RS09735	COG1028	Short-chain dehydrogenase reductase Sdr
C1192_RS09740	COG1535	isochorismatase
C1192_RS09740	COG3433	isochorismatase activity
C1192_RS09745	COG1021	2,3-dihydroxybenzoate-AMP ligase
C1192_RS09750	COG1169	isochorismate synthase
C1192_RS09755	COG4592	Periplasmic binding protein
C1192_RS09765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1192_RS09770	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1192_RS09775	COG1120	ATPase activity
C1192_RS09780	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C1192_RS09785	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C1192_RS09785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C1192_RS09790	COG3251	PFAM MbtH domain protein
C1192_RS09795	COG2382	esterase
C1192_RS09800	COG4771	TonB-dependent receptor
C1192_RS09805	COG2977	Belongs to the P-Pant transferase superfamily
C1192_RS09830	COG2315	Protein conserved in bacteria
C1192_RS09835	COG0778	Nitroreductase
C1192_RS09840	COG0668	transmembrane transport
C1192_RS09845	COG1113	amino acid transport
C1192_RS09850	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1192_RS09855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1192_RS09860	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1192_RS09865	COG1538	Outer membrane efflux protein
C1192_RS09870	COG0745	RESPONSE REGULATOR receiver
C1192_RS09875	COG5002	protein histidine kinase activity
C1192_RS09880	COG1215	transferase activity, transferring glycosyl groups
C1192_RS09885	COG4783	chaperone-mediated protein folding
C1192_RS09900	COG2076	Multidrug Resistance protein
C1192_RS09925	COG2501	S4 domain
C1192_RS09930	COG1988	membrane-bound metal-dependent
C1192_RS09940	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C1192_RS09960	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C1192_RS09965	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C1192_RS09970	COG0549	Belongs to the carbamate kinase family
C1192_RS09980	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C1192_RS09990	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C1192_RS09995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1192_RS10000	COG3257	ureidoglycine aminohydrolase activity
C1192_RS10005	COG1929	Belongs to the glycerate kinase type-1 family
C1192_RS10010	COG2233	PERMEase
C1192_RS10020	COG3328	transposase activity
C1192_RS10025	COG3385	transposase activity
C1192_RS10035	COG1953	Uracil, thiamine, allantoin
C1192_RS10040	COG2084	Dehydrogenase
C1192_RS10045	COG3622	Belongs to the hyi family
C1192_RS10050	COG3960	tartronate-semialdehyde synthase activity
C1192_RS10055	COG1414	Transcriptional regulator
C1192_RS10080	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C1192_RS10085	COG4181	ATPase activity
C1192_RS10090	COG2755	lipolytic protein G-D-S-L family
C1192_RS10095	COG0300	oxidoreductase activity
C1192_RS10100	COG3118	belongs to the thioredoxin family
C1192_RS10105	COG0390	transport system, permease component
C1192_RS10110	COG4619	ABC transporter
C1192_RS10115	COG0330	HflC and HflK could
C1192_RS10120	COG1585	Membrane protein implicated in regulation of membrane protease activity
C1192_RS10145	COG0789	Transcriptional regulator
C1192_RS10160	COG0531	amino acid
C1192_RS10170	COG2217	Heavy metal translocating P-type atpase
C1192_RS10175	COG3735	TraB family
C1192_RS10185	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C1192_RS10195	COG3328	transposase activity
C1192_RS10210	COG3328	transposase activity
C1192_RS10225	COG2223	nitrite transmembrane transporter activity
C1192_RS10230	COG4651	solute:proton antiporter activity
C1192_RS10230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C1192_RS10235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1192_RS10275	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C1192_RS10290	COG2832	Protein of unknown function (DUF454)
C1192_RS10295	COG3923	Primosomal replication protein n
C1192_RS10305	COG1196	nuclear chromosome segregation
C1192_RS10305	COG3264	Mechanosensitive ion channel
C1192_RS10315	COG1309	transcriptional regulator
C1192_RS10320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1192_RS10325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1192_RS10340	COG0110	maltose O-acetyltransferase activity
C1192_RS10350	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C1192_RS10355	COG5507	3-demethylubiquinone-9 3-methyltransferase
C1192_RS10365	COG3695	enzyme binding
C1192_RS10370	COG3126	Type III secretion system lipoprotein chaperone (YscW)
C1192_RS10375	COG1946	Acyl-CoA thioesterase
C1192_RS10380	COG0004	ammonium transporteR
C1192_RS10385	COG0347	Belongs to the P(II) protein family
C1192_RS10390	COG1132	(ABC) transporter
C1192_RS10395	COG1132	(ABC) transporter
C1192_RS10400	COG1522	sequence-specific DNA binding
C1192_RS10420	COG0824	Thioesterase
C1192_RS10425	COG1555	photosystem II stabilization
C1192_RS10430	COG4372	Transposase
C1192_RS10435	COG3436	PFAM IS66 Orf2 family protein
C1192_RS10450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C1192_RS10455	COG0776	regulation of translation
C1192_RS10460	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C1192_RS10485	COG0271	Belongs to the BolA IbaG family
C1192_RS10495	COG3056	Lipoprotein
C1192_RS10500	COG2223	nitrite transmembrane transporter activity
C1192_RS10505	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C1192_RS10510	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C1192_RS10515	COG1845	cytochrome c oxidase, subunit III
C1192_RS10520	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C1192_RS10530	COG2814	Major facilitator Superfamily
C1192_RS10540	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C1192_RS10545	COG0693	protein deglycase activity
C1192_RS10560	COG0142	geranyltranstransferase activity
C1192_RS10570	COG0667	Aldo Keto reductase
C1192_RS10575	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C1192_RS10580	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C1192_RS10595	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C1192_RS10595	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C1192_RS10605	COG4238	major outer membrane lipoprotein
C1192_RS10610	COG3248	Nucleoside-binding outer membrane protein
C1192_RS10615	COG1403	HNH endonuclease
C1192_RS10625	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1192_RS10630	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1192_RS10635	COG1862	Preprotein translocase
C1192_RS10655	COG0366	Alpha amylase catalytic
C1192_RS10660	COG1113	amino acid transport
C1192_RS10665	COG1114	Component of the transport system for branched-chain amino acids
C1192_RS10670	COG5002	protein histidine kinase activity
C1192_RS10675	COG0745	RESPONSE REGULATOR receiver
C1192_RS10680	COG0420	3'-5' exonuclease activity
C1192_RS10685	COG0419	ATPase involved in DNA repair
C1192_RS10690	COG2814	Major facilitator Superfamily
C1192_RS10695	COG1940	carbohydrate kinase activity
C1192_RS10710	COG4126	flavin adenine dinucleotide binding
C1192_RS10735	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C1192_RS10740	COG3706	GGDEF domain
C1192_RS10750	COG1785	Belongs to the alkaline phosphatase family
C1192_RS10760	COG1181	Belongs to the D-alanine--D-alanine ligase family
C1192_RS10785	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C1192_RS10795	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C1192_RS10800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1192_RS10805	COG3468	outer membrane autotransporter barrel domain protein
C1192_RS10810	COG3328	transposase activity
C1192_RS10820	COG0113	porphobilinogen synthase activity
C1192_RS10825	COG2175	clavaminate synthase activity
C1192_RS10840	COG4521	taurine ABC transporter
C1192_RS10850	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C1192_RS10865	COG1215	transferase activity, transferring glycosyl groups
C1192_RS10890	COG3122	Protein conserved in bacteria
C1192_RS10895	COG2814	Major facilitator Superfamily
C1192_RS10930	COG1414	Transcriptional regulator
C1192_RS10935	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C1192_RS10945	COG1609	Transcriptional regulator
C1192_RS10960	COG2223	nitrite transmembrane transporter activity
C1192_RS10965	COG0110	maltose O-acetyltransferase activity
C1192_RS10970	COG0402	S-adenosylhomocysteine deaminase activity
C1192_RS10980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1192_RS10985	COG2079	MmgE PrpD family protein
C1192_RS10990	COG0372	Belongs to the citrate synthase family
C1192_RS10995	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C1192_RS11000	COG3829	transcription factor binding
C1192_RS11020	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C1192_RS11045	COG0402	S-adenosylhomocysteine deaminase activity
C1192_RS11050	COG0549	Belongs to the carbamate kinase family
C1192_RS11055	COG1304	FMN binding
C1192_RS11060	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C1192_RS11070	COG0666	response to abiotic stimulus
C1192_RS11085	COG0583	DNA-binding transcription factor activity
C1192_RS11090	COG2200	EAL domain
C1192_RS11090	COG2771	luxR family
C1192_RS11100	COG1556	Lactate utilization protein
C1192_RS11105	COG1139	Iron-sulfur cluster binding protein
C1192_RS11110	COG0247	lactate metabolic process
C1192_RS11115	COG1620	l-lactate permease
C1192_RS11120	COG2207	Transcriptional regulator
C1192_RS11125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1192_RS11160	COG5002	protein histidine kinase activity
C1192_RS11180	COG1064	alcohol dehydrogenase
C1192_RS11185	COG0656	L-ascorbic acid biosynthetic process
C1192_RS11190	COG4372	Transposase
C1192_RS11195	COG3436	PFAM IS66 Orf2 family protein
C1192_RS11205	COG0656	L-ascorbic acid biosynthetic process
C1192_RS11210	COG0667	Aldo Keto reductase
C1192_RS11220	COG0702	epimerase
C1192_RS11265	COG1120	ATPase activity
C1192_RS11270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1192_RS11275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C1192_RS11285	COG3477	response to acidic pH
C1192_RS11310	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C1192_RS11330	COG2195	Cleaves the N-terminal amino acid of tripeptides
C1192_RS11345	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C1192_RS11350	COG1690	Belongs to the RtcB family
C1192_RS11355	COG0454	-acetyltransferase
C1192_RS11370	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C1192_RS11375	COG1191	sigma factor activity
C1192_RS11400	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C1192_RS11405	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1192_RS11420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C1192_RS11445	COG4786	Flagellar basal body rod
C1192_RS11450	COG4787	bacterial-type flagellum-dependent cell motility
C1192_RS11455	COG1749	Flagellar hook protein flgE
C1192_RS11470	COG1558	bacterial-type flagellum-dependent cell motility
C1192_RS11475	COG1815	bacterial-type flagellum-dependent cell motility
C1192_RS11505	COG3177	Filamentation induced by cAMP protein fic
C1192_RS11510	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C1192_RS11530	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C1192_RS11540	COG1677	Flagellar hook-basal body complex protein FliE
C1192_RS11565	COG1987	bacterial-type flagellum assembly
C1192_RS11590	COG0791	NLP P60 protein
C1192_RS11595	COG3034	peptidoglycan biosynthetic process
C1192_RS11600	COG0121	glutamine amidotransferase
C1192_RS11610	COG1960	acyl-CoA dehydrogenase activity
C1192_RS11620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1192_RS11640	COG3328	transposase activity
C1192_RS11660	COG4372	Transposase
C1192_RS11665	COG3436	PFAM IS66 Orf2 family protein
C1192_RS11685	COG3209	COG3209 Rhs family protein
C1192_RS11740	COG2885	chlorophyll binding
C1192_RS11820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C1192_RS11830	COG2226	methyltransferase
C1192_RS11840	COG0741	lytic transglycosylase activity
C1192_RS11840	COG1388	LysM domain
C1192_RS11845	COG3328	transposase activity
C1192_RS11850	COG2226	methyltransferase
C1192_RS11865	COG3436	PFAM IS66 Orf2 family protein
C1192_RS11870	COG4372	Transposase
C1192_RS11880	COG0583	DNA-binding transcription factor activity
C1192_RS11885	COG0656	L-ascorbic acid biosynthetic process
C1192_RS11920	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C1192_RS11925	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C1192_RS11930	COG2011	ABC-type metal ion transport system permease component
C1192_RS11935	COG1464	Belongs to the NlpA lipoprotein family
C1192_RS11945	COG1720	tRNA m6t6A37 methyltransferase activity
C1192_RS11955	COG0791	NLP P60 protein
C1192_RS11960	COG3015	lipoprotein NlpE involved in copper resistance
C1192_RS11965	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C1192_RS11970	COG4681	YaeQ
C1192_RS11980	COG4568	rho-dependent transcription termination
C1192_RS11990	COG0346	lactoylglutathione lyase activity
C1192_RS12010	COG0587	DNA-directed DNA polymerase activity
C1192_RS12035	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C1192_RS12040	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
C1192_RS12050	COG0750	zinc metalloprotease
C1192_RS12055	COG0575	Belongs to the CDS family
C1192_RS12060	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C1192_RS12065	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C1192_RS12100	COG0024	Methionine aminopeptidase
C1192_RS12115	COG1408	metallophosphoesterase
C1192_RS12125	COG3835	regulator
C1192_RS12130	COG3344	reverse transcriptase
C1192_RS12135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1192_RS12155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C1192_RS12160	COG2860	membrane
C1192_RS12180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1192_RS12185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C1192_RS12190	COG1120	ATPase activity
C1192_RS12195	COG4774	siderophore transport
C1192_RS12200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C1192_RS12210	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C1192_RS12220	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C1192_RS12230	COG0617	tRNA 3'-terminal CCA addition
C1192_RS12235	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C1192_RS12240	COG3539	Fimbrial protein
C1192_RS12245	COG3121	Chaperone
C1192_RS12250	COG3188	usher protein
C1192_RS12265	COG3539	Fimbrial protein
C1192_RS12275	COG3539	Fimbrial protein
C1192_RS12285	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C1192_RS12290	COG5464	transposase or invertase
C1192_RS12295	COG5464	transposase or invertase
C1192_RS12315	COG0726	polysaccharide deacetylase
C1192_RS12325	COG0842	Transport permease protein
C1192_RS12330	COG1131	(ABC) transporter
C1192_RS12335	COG0288	reversible hydration of carbon dioxide
C1192_RS12340	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C1192_RS12345	COG4993	Dehydrogenase
C1192_RS12350	COG2132	Multicopper oxidase
C1192_RS12385	COG1049	propionate catabolic process, 2-methylcitrate cycle
C1192_RS12395	COG3064	Membrane
C1192_RS12395	COG3064	Membrane
C1192_RS12400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1192_RS12405	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1192_RS12410	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C1192_RS12420	COG2186	Transcriptional regulator
C1192_RS12425	COG1113	amino acid transport
C1192_RS12430	COG3725	Membrane protein required for beta-lactamase induction
C1192_RS12435	COG3023	N-Acetylmuramoyl-L-alanine amidase
C1192_RS12440	COG0157	Belongs to the NadC ModD family
C1192_RS12445	COG4969	Belongs to the N-Me-Phe pilin family
C1192_RS12450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C1192_RS12455	COG1459	type II secretion system
C1192_RS12465	COG0237	dephospho-CoA kinase activity
C1192_RS12480	COG0494	nUDIX hydrolase
C1192_RS12500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C1192_RS12505	COG0849	cell division
C1192_RS12510	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C1192_RS12515	COG1181	Belongs to the D-alanine--D-alanine ligase family
C1192_RS12530	COG0772	Belongs to the SEDS family
C1192_RS12545	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C1192_RS12550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C1192_RS12555	COG0768	penicillin binding
C1192_RS12560	COG3116	cell division
C1192_RS12575	COG1609	Transcriptional regulator
C1192_RS12580	COG0440	acetolactate synthase activity
C1192_RS12585	COG0028	Belongs to the TPP enzyme family
C1192_RS12590	COG0583	DNA-binding transcription factor activity
C1192_RS12630	COG4143	(ABC) transporter
C1192_RS12635	COG1178	ABC-type Fe3 transport system permease component
C1192_RS12640	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
C1192_RS12645	COG0586	Pfam SNARE associated Golgi protein
C1192_RS12650	COG4977	sequence-specific DNA binding
C1192_RS12675	COG0235	Class ii aldolase
C1192_RS12680	COG0417	DNA replication proofreading
C1192_RS12690	COG0564	pseudouridine synthase activity
C1192_RS12695	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C1192_RS12705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C1192_RS12730	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C1192_RS12750	COG2271	Major facilitator Superfamily
C1192_RS12755	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C1192_RS12760	COG0644	oxidoreductase
C1192_RS12820	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C1192_RS12825	COG0505	Belongs to the CarA family
C1192_RS12845	COG1047	Peptidyl-prolyl cis-trans
C1192_RS12860	COG0196	riboflavin kinase activity
C1192_RS12875	COG0583	DNA-binding transcription factor activity
C1192_RS12880	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C1192_RS12910	COG1584	GPR1 FUN34 yaaH family protein
C1192_RS12915	COG0521	Mo-molybdopterin cofactor biosynthetic process
C1192_RS12925	COG1115	amino acid carrier protein
C1192_RS12940	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C1192_RS12950	COG0527	aspartate kinase activity
C1192_RS12950	COG0460	homoserine dehydrogenase
C1192_RS12960	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C1192_RS12970	COG0745	RESPONSE REGULATOR receiver
C1192_RS12975	COG4452	Inner membrane protein CreD
C1192_RS12980	COG2205	protein histidine kinase activity
C1192_RS12985	COG0745	RESPONSE REGULATOR receiver
C1192_RS12990	COG3045	CreA protein
C1192_RS12995	COG3708	Transcriptional regulator
C1192_RS12995	COG2207	Transcriptional regulator
C1192_RS13015	COG0741	lytic transglycosylase activity
C1192_RS13025	COG0488	(ABC) transporter
C1192_RS13030	COG1056	cytidyltransferase-related domain
C1192_RS13030	COG3172	ATPase kinase involved in NAD metabolism
C1192_RS13035	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C1192_RS13040	COG0560	Phosphoserine phosphatase
C1192_RS13045	COG3726	membrane protein affecting hemolysin expression
C1192_RS13080	COG1328	CTP reductase activity
C1192_RS13085	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C1192_RS13090	COG0084	hydrolase, TatD family'
C1192_RS13095	COG4667	esterase of the alpha-beta hydrolase superfamily
C1192_RS13105	COG2823	Periplasmic or secreted lipoprotein
C1192_RS13115	COG1011	Hydrolase
C1192_RS13120	COG0456	acetyltransferase
C1192_RS13125	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
C1192_RS13155	COG4114	ferric iron reductase
C1192_RS13160	COG2197	response regulator
C1192_RS13165	COG2197	response regulator
C1192_RS13170	COG2966	Psort location CytoplasmicMembrane, score
C1192_RS13185	COG1484	DNA-dependent DNA replication
C1192_RS13200	COG1063	alcohol dehydrogenase
C1192_RS13205	COG1802	Transcriptional regulator
C1192_RS13210	COG0025	NhaP-type Na H and K H
C1192_RS13215	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C1192_RS13225	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C1192_RS13230	COG0840	transmembrane signaling receptor activity
C1192_RS13240	COG1966	Carbon starvation protein
C1192_RS13245	COG2879	small protein
C1192_RS13250	COG0523	cobalamin synthesis protein
C1192_RS13255	COG1715	Restriction endonuclease
C1192_RS13270	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C1192_RS13305	COG2733	membrane
C1192_RS13310	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
C1192_RS13330	COG0477	Major facilitator Superfamily
C1192_RS13345	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C1192_RS13355	COG2186	Transcriptional regulator
C1192_RS13360	COG0246	Mannitol dehydrogenase
C1192_RS13375	COG2610	gluconate transmembrane transporter activity
C1192_RS13380	COG3539	Fimbrial protein
C1192_RS13385	COG3539	Fimbrial protein
C1192_RS13390	COG3539	Fimbrial protein
C1192_RS13395	COG3188	usher protein
C1192_RS13400	COG3121	Chaperone
C1192_RS13405	COG3539	Fimbrial protein
C1192_RS13420	COG4974	Belongs to the 'phage' integrase family
C1192_RS13425	COG0582	viral genome integration into host DNA
C1192_RS13450	COG3436	PFAM IS66 Orf2 family protein
C1192_RS13455	COG4372	Transposase
C1192_RS13490	COG3328	transposase activity
C1192_RS13495	COG0701	Predicted permease
C1192_RS13500	COG0702	epimerase
C1192_RS13515	COG3153	acetyltransferase
C1192_RS13520	COG3154	lipid carrier protein
C1192_RS13525	COG0826	peptidase U32
C1192_RS13530	COG0826	peptidase U32
C1192_RS13535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C1192_RS13540	COG0814	amino acid
C1192_RS13545	COG0513	Belongs to the DEAD box helicase family
C1192_RS13585	COG0195	Participates in both transcription termination and antitermination
C1192_RS13620	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C1192_RS13630	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C1192_RS13635	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C1192_RS13645	COG1534	Rna-binding protein
C1192_RS13650	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C1192_RS13655	COG2027	D-alanyl-D-alanine carboxypeptidase
C1192_RS13660	COG3344	reverse transcriptase
C1192_RS13670	COG0697	spore germination
C1192_RS13685	COG0142	geranyltranstransferase activity
C1192_RS13690	COG3423	Transcriptional regulator
C1192_RS13700	COG5007	Belongs to the BolA IbaG family
C1192_RS13705	COG3113	response to antibiotic
C1192_RS13710	COG2854	intermembrane phospholipid transfer
C1192_RS13715	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C1192_RS13720	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C1192_RS13725	COG1127	ABC transporter
C1192_RS13730	COG0530	calcium, potassium:sodium antiporter activity
C1192_RS13735	COG0517	IMP dehydrogenase activity
C1192_RS13735	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C1192_RS13740	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C1192_RS13745	COG3117	lipopolysaccharide transmembrane transporter activity
C1192_RS13750	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C1192_RS13755	COG1137	ATPase activity
C1192_RS13760	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C1192_RS13765	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C1192_RS13780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1192_RS13785	COG0515	serine threonine protein kinase
C1192_RS13795	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C1192_RS13800	COG0784	Response regulator, receiver
C1192_RS13800	COG5002	protein histidine kinase activity
C1192_RS13800	COG2198	Histidine kinase
C1192_RS13805	COG1242	4 iron, 4 sulfur cluster binding
C1192_RS13815	COG0067	glutamate synthase
C1192_RS13815	COG0069	glutamate synthase activity
C1192_RS13815	COG0070	glutamate synthase
C1192_RS13820	COG0493	'glutamate synthase
C1192_RS13825	COG3539	Fimbrial protein
C1192_RS13830	COG3188	usher protein
C1192_RS13835	COG3121	Chaperone
C1192_RS13840	COG3539	Fimbrial protein
C1192_RS13845	COG3539	Fimbrial protein
C1192_RS13850	COG3539	Fimbrial protein
C1192_RS13860	COG2731	YhcH YjgK YiaL family protein
C1192_RS13875	COG2814	Major facilitator Superfamily
C1192_RS13890	COG2969	positive regulation of protein catabolic process
C1192_RS13895	COG0625	glutathione transferase activity
C1192_RS13920	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C1192_RS13925	COG3105	Protein conserved in bacteria
C1192_RS13930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1192_RS13935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1192_RS13940	COG3328	transposase activity
C1192_RS13945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1192_RS13960	COG4948	Mandelate Racemase Muconate Lactonizing
C1192_RS13965	COG1063	alcohol dehydrogenase
C1192_RS13975	COG0582	viral genome integration into host DNA
C1192_RS13985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C1192_RS14015	COG1396	sequence-specific DNA binding
C1192_RS14030	COG1846	Transcriptional regulator
C1192_RS14045	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C1192_RS14070	COG3385	transposase activity
C1192_RS14090	COG2732	(Barnase) inhibitor
C1192_RS14110	COG0583	DNA-binding transcription factor activity
C1192_RS14115	COG0312	modulator of DNA gyrase
C1192_RS14120	COG3164	Protein of unknown function
C1192_RS14125	COG1530	ribonuclease E activity
C1192_RS14135	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C1192_RS14140	COG1792	Involved in formation and maintenance of cell shape
C1192_RS14145	COG1077	Cell shape determining protein MreB Mrl
C1192_RS14160	COG2200	EAL domain
C1192_RS14160	COG2199	diguanylate cyclase activity
C1192_RS14165	COG0604	alcohol dehydrogenase
C1192_RS14185	COG0511	ligase activity, forming carbon-carbon bonds
C1192_RS14190	COG0439	Biotin carboxylase
C1192_RS14195	COG3924	membrane
C1192_RS14200	COG4145	pantothenate transmembrane transporter activity
C1192_RS14210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C1192_RS14220	COG2189	Belongs to the N(4) N(6)-methyltransferase family
C1192_RS14230	COG1309	transcriptional regulator
C1192_RS14240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1192_RS14245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1192_RS14260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1192_RS14265	COG4597	amino acid ABC transporter
C1192_RS14270	COG0765	amino acid transport
C1192_RS14275	COG1126	abc transporter atp-binding protein
C1192_RS14305	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C1192_RS14325	COG0551	DNA topoisomerase type I activity
C1192_RS14335	COG0758	DNA mediated transformation
C1192_RS14355	COG0569	domain protein
C1192_RS14365	COG3036	rescue of stalled ribosome
C1192_RS14370	COG0789	Transcriptional regulator
C1192_RS14380	COG0203	ribosomal protein L17
C1192_RS14410	COG0201	protein transport
C1192_RS14500	COG0089	rRNA binding
C1192_RS14580	COG2964	Protein conserved in bacteria
C1192_RS14585	COG0545	Peptidyl-prolyl cis-trans isomerase
C1192_RS14595	COG1047	Peptidyl-prolyl cis-trans
C1192_RS14600	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C1192_RS14620	COG0488	(ABC) transporter
C1192_RS14625	COG0429	hydrolase of the alpha beta-hydrolase fold
C1192_RS14635	COG3954	Phosphoribulokinase
C1192_RS14640	COG1765	OsmC-like protein
C1192_RS14650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1192_RS14655	COG1289	transmembrane transporter activity
C1192_RS14660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C1192_RS14665	COG0512	Glutamine amidotransferase of anthranilate synthase
C1192_RS14680	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C1192_RS14695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C1192_RS14700	COG2146	nitrite reductase [NAD(P)H] activity
C1192_RS14705	COG2116	formate transmembrane transporter activity
C1192_RS14720	COG0626	cystathionine gamma-synthase activity
C1192_RS14735	COG1735	metal-dependent hydrolase with the TIM-barrel fold
C1192_RS14740	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C1192_RS14745	COG3457	Alanine racemase
C1192_RS14755	COG2188	Transcriptional regulator
C1192_RS14765	COG0180	Tryptophanyl-tRNA synthetase
C1192_RS14770	COG0546	phosphoglycolate phosphatase activity
C1192_RS14775	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C1192_RS14780	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C1192_RS14785	COG3266	domain, Protein
C1192_RS14800	COG4796	Type ii and iii secretion system protein
C1192_RS14815	COG3166	PFAM Fimbrial assembly family protein
C1192_RS14820	COG4972	Pilus assembly protein
C1192_RS14825	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C1192_RS14830	COG0494	nUDIX hydrolase
C1192_RS14840	COG1011	Hydrolase
C1192_RS14845	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C1192_RS14855	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C1192_RS14885	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C1192_RS14890	COG2183	response to ionizing radiation
C1192_RS14900	COG1918	ferrous iron import across plasma membrane
C1192_RS14905	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C1192_RS14920	COG5464	transposase or invertase
C1192_RS14950	COG2610	gluconate transmembrane transporter activity
C1192_RS14955	COG1640	4-alpha-glucanotransferase
C1192_RS14960	COG0058	SHG alpha-glucan phosphorylase activity
C1192_RS14975	COG1690	Belongs to the RtcB family
C1192_RS14980	COG4650	regulator
C1192_RS14985	COG1349	DNA-binding transcription factor activity
C1192_RS15000	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C1192_RS15015	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C1192_RS15025	COG3121	Chaperone
C1192_RS15040	COG3188	usher protein
C1192_RS15045	COG3121	Chaperone
C1192_RS15060	COG3436	PFAM IS66 Orf2 family protein
C1192_RS15065	COG4372	Transposase
C1192_RS15070	COG0058	SHG alpha-glucan phosphorylase activity
C1192_RS15095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C1192_RS15100	COG2095	MarC family integral membrane protein
C1192_RS15105	COG2610	gluconate transmembrane transporter activity
C1192_RS15110	COG3265	gluconokinase activity
C1192_RS15115	COG1609	Transcriptional regulator
C1192_RS15120	COG1741	Belongs to the pirin family
C1192_RS15125	COG0673	inositol 2-dehydrogenase activity
C1192_RS15130	COG1247	-acetyltransferase
C1192_RS15135	COG0405	Gamma-glutamyltransferase
C1192_RS15145	COG0584	glycerophosphoryl diester phosphodiesterase
C1192_RS15160	COG1175	transmembrane transport
C1192_RS15165	COG1653	transport
C1192_RS15170	COG0410	ABC transporter
C1192_RS15175	COG0411	ABC transporter
C1192_RS15180	COG4177	L-phenylalanine transmembrane transporter activity
C1192_RS15185	COG0559	Belongs to the binding-protein-dependent transport system permease family
C1192_RS15190	COG0683	leucine binding
C1192_RS15195	COG0456	acetyltransferase
C1192_RS15200	COG0683	leucine binding
C1192_RS15225	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C1192_RS15230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C1192_RS15235	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C1192_RS15240	COG2177	Part of the ABC transporter FtsEX involved in
C1192_RS15245	COG2884	Cell division ATP-binding protein ftsE
C1192_RS15250	COG0552	protein localization to endoplasmic reticulum
C1192_RS15255	COG0742	ribosomal rna small subunit methyltransferase
C1192_RS15260	COG3776	membrane
C1192_RS15270	COG3714	YhhN family
C1192_RS15290	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C1192_RS15305	COG0628	permease
C1192_RS15310	COG2091	lysine biosynthetic process via aminoadipic acid
C1192_RS15315	COG0747	negative chemotaxis
C1192_RS15320	COG0601	transmembrane transport
C1192_RS15325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1192_RS15335	COG1124	(ABC) transporter
C1192_RS15345	COG0842	Transport permease protein
C1192_RS15350	COG0842	Transport permease protein
C1192_RS15350	COG1129	ABC transporter
C1192_RS15355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1192_RS15365	COG2081	HI0933 family
C1192_RS15370	COG0306	phosphate transporter
C1192_RS15380	COG0589	response to stress
C1192_RS15390	COG3104	oligopeptide transport
C1192_RS15400	COG0339	signal peptide processing
C1192_RS15405	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C1192_RS15410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1192_RS15420	COG0640	Transcriptional regulator
C1192_RS15425	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C1192_RS15430	COG1393	Belongs to the ArsC family
C1192_RS15435	COG3065	identical protein binding
C1192_RS15450	COG3720	iron ion transport
C1192_RS15455	COG4771	TonB-dependent receptor
C1192_RS15465	COG4558	Periplasmic binding protein
C1192_RS15475	COG3721	Heme iron utilization protein
C1192_RS15485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1192_RS15495	COG1285	pathogenesis
C1192_RS15510	COG3247	response to pH
C1192_RS15515	COG2771	luxR family
C1192_RS15525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1192_RS15530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1192_RS15540	COG2207	Transcriptional regulator
C1192_RS15550	COG0076	glutamate decarboxylase activity
C1192_RS15560	COG3385	transposase activity
C1192_RS15565	COG2197	response regulator
C1192_RS15570	COG0583	DNA-binding transcription factor activity
C1192_RS15575	COG1295	ribonuclease BN
C1192_RS15580	COG0477	Major facilitator Superfamily
C1192_RS15585	COG2982	Protein involved in outer membrane biogenesis
C1192_RS15590	COG2200	EAL domain
C1192_RS15600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1192_RS15620	COG0612	Peptidase, M16
C1192_RS15645	COG2200	EAL domain
C1192_RS15645	COG2199	diguanylate cyclase activity
C1192_RS15650	COG3118	belongs to the thioredoxin family
C1192_RS15650	COG0457	Tetratricopeptide repeat
C1192_RS15655	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C1192_RS15660	COG1215	transferase activity, transferring glycosyl groups
C1192_RS15665	COG1215	transferase activity, transferring glycosyl groups
C1192_RS15690	COG2194	sulfuric ester hydrolase activity
C1192_RS15710	COG0814	amino acid
C1192_RS15715	COG4608	Belongs to the ABC transporter superfamily
C1192_RS15720	COG0444	Belongs to the ABC transporter superfamily
C1192_RS15725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1192_RS15730	COG0601	transmembrane transport
C1192_RS15735	COG0747	negative chemotaxis
C1192_RS15755	COG2194	sulfuric ester hydrolase activity
C1192_RS15765	COG2223	nitrite transmembrane transporter activity
C1192_RS15770	COG5571	outer membrane autotransporter
C1192_RS15775	COG2818	Glycosylase
C1192_RS15780	COG0456	acetyltransferase
C1192_RS15785	COG0243	molybdopterin cofactor binding
C1192_RS15790	COG2885	chlorophyll binding
C1192_RS15805	COG2944	sequence-specific DNA binding
C1192_RS15810	COG1278	Cold shock
C1192_RS15845	COG3274	enterobacterial common antigen metabolic process
C1192_RS15850	COG4682	membrane
C1192_RS15855	COG4682	membrane
C1192_RS15860	COG1070	Carbohydrate kinase
C1192_RS15870	COG4213	ABC transporter substrate-binding protein
C1192_RS15880	COG4214	carbohydrate transport
C1192_RS15885	COG1609	Transcriptional regulator
C1192_RS15885	COG2207	Transcriptional regulator
C1192_RS15890	COG2992	FlgJ-related protein
C1192_RS15900	COG0366	Alpha amylase catalytic
C1192_RS15910	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1192_RS15915	COG1414	Transcriptional regulator
C1192_RS15925	COG2731	YhcH YjgK YiaL family protein
C1192_RS15935	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C1192_RS15940	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C1192_RS15945	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C1192_RS15950	COG1070	Carbohydrate kinase
C1192_RS15955	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C1192_RS15960	COG3623	hexulose-6-phosphate isomerase
C1192_RS15965	COG0235	Class ii aldolase
C1192_RS15980	COG0326	Molecular chaperone. Has ATPase activity
C1192_RS15995	COG0243	molybdopterin cofactor binding
C1192_RS15995	COG3383	formate dehydrogenase (NAD+) activity
C1192_RS16000	COG0243	molybdopterin cofactor binding
C1192_RS16000	COG3383	formate dehydrogenase (NAD+) activity
C1192_RS16005	COG0437	4 iron, 4 sulfur cluster binding
C1192_RS16010	COG2864	formate dehydrogenase
C1192_RS16025	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C1192_RS16030	COG4372	Transposase
C1192_RS16035	COG3436	PFAM IS66 Orf2 family protein
C1192_RS16050	COG0456	acetyltransferase
C1192_RS16065	COG1011	Hydrolase
C1192_RS16075	COG0477	Major facilitator Superfamily
C1192_RS16085	COG1063	alcohol dehydrogenase
C1192_RS16090	COG3684	Belongs to the aldolase LacD family
C1192_RS16100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1192_RS16105	COG1349	DNA-binding transcription factor activity
C1192_RS16130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C1192_RS16140	COG0561	phosphatase activity
C1192_RS16145	COG1217	gtp-binding protein TYPA
C1192_RS16155	COG0174	glutamine synthetase
C1192_RS16160	COG3852	Histidine kinase
C1192_RS16165	COG2204	response regulator
C1192_RS16175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C1192_RS16200	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C1192_RS16200	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C1192_RS16210	COG0204	Acyl-transferase
C1192_RS16215	COG5339	Protein conserved in bacteria
C1192_RS16220	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C1192_RS16225	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C1192_RS16230	COG3084	Protein conserved in bacteria
C1192_RS16235	COG0746	molybdenum cofactor guanylyltransferase activity
C1192_RS16240	COG1763	Mo-molybdopterin cofactor biosynthetic process
C1192_RS16265	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
C1192_RS16270	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1192_RS16275	COG1739	Uncharacterized protein family UPF0029
C1192_RS16295	COG0543	2 iron, 2 sulfur cluster binding
C1192_RS16305	COG0250	Participates in transcription elongation, termination and antitermination
C1192_RS16315	COG0805	protein transport
C1192_RS16320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C1192_RS16325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C1192_RS16335	COG3165	ubiquinone biosynthetic process from chorismate
C1192_RS16345	COG1322	Protein conserved in bacteria
C1192_RS16350	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C1192_RS16355	COG0412	Dienelactone hydrolase
C1192_RS16360	COG1335	isochorismatase
C1192_RS16370	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C1192_RS16375	COG1304	FMN binding
C1192_RS16380	COG0549	Belongs to the carbamate kinase family
C1192_RS16390	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C1192_RS16395	COG0583	DNA-binding transcription factor activity
C1192_RS16405	COG0583	DNA-binding transcription factor activity
C1192_RS16410	COG0697	spore germination
C1192_RS16415	COG0561	phosphatase activity
C1192_RS16420	COG2267	carboxylic ester hydrolase activity
C1192_RS16425	COG1280	lysine exporter protein (LysE YggA)
C1192_RS16435	COG0514	ATP-dependent DNA helicase (RecQ)
C1192_RS16440	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
C1192_RS16445	COG2050	protein possibly involved in aromatic compounds catabolism
C1192_RS16450	COG2962	Rard protein
C1192_RS16465	COG0598	Magnesium transport protein CorA
C1192_RS16470	COG3698	Phosphodiester glycosidase
C1192_RS16475	COG0210	DNA helicase
C1192_RS16480	COG1011	Hydrolase
C1192_RS16490	COG3159	Protein conserved in bacteria
C1192_RS16500	COG5567	small periplasmic lipoprotein
C1192_RS16520	COG3072	Adenylate cyclase
C1192_RS16535	COG1587	Uroporphyrinogen-III synthase
C1192_RS16540	COG2959	enzyme of heme biosynthesis
C1192_RS16545	COG3071	HemY protein
C1192_RS16550	COG3119	arylsulfatase activity
C1192_RS16560	COG0641	radical SAM
C1192_RS16585	COG1113	amino acid transport
C1192_RS16605	COG2244	polysaccharide biosynthetic process
C1192_RS16610	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C1192_RS16615	COG0456	acetyltransferase
C1192_RS16620	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C1192_RS16625	COG1088	dTDP-glucose 4,6-dehydratase activity
C1192_RS16630	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C1192_RS16635	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C1192_RS16640	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C1192_RS16645	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C1192_RS16655	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C1192_RS16665	COG3118	belongs to the thioredoxin family
C1192_RS16685	COG0210	DNA helicase
C1192_RS16690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C1192_RS16700	COG0583	DNA-binding transcription factor activity
C1192_RS16705	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C1192_RS16715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C1192_RS16720	COG3978	acetolactate synthase activity
C1192_RS16745	COG3085	chromosome segregation
C1192_RS16785	COG2186	Transcriptional regulator
C1192_RS16795	COG1609	Transcriptional regulator
C1192_RS16800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1192_RS16805	COG1879	ABC-type sugar transport system periplasmic component
C1192_RS16810	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1192_RS16815	COG1129	ABC transporter
C1192_RS16845	COG1522	sequence-specific DNA binding
C1192_RS16850	COG0716	FMN binding
C1192_RS16865	COG3312	ion transport
C1192_RS16915	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C1192_RS16920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C1192_RS16925	COG0573	inorganic phosphate transmembrane transporter activity
C1192_RS16930	COG0581	inorganic phosphate transmembrane transporter activity
C1192_RS16935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C1192_RS16940	COG0704	Plays a role in the regulation of phosphate uptake
C1192_RS16945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1192_RS16950	COG2252	PERMEase
C1192_RS16955	COG0431	NADPH-dependent FMN reductase
C1192_RS16960	COG2091	lysine biosynthetic process via aminoadipic acid
C1192_RS16975	COG0814	amino acid
C1192_RS17025	COG0592	DNA-directed DNA polymerase activity
C1192_RS17035	COG0187	DNA topoisomerase II activity
C1192_RS17040	COG3753	Protein conserved in bacteria
C1192_RS17045	COG0561	phosphatase activity
C1192_RS17055	COG2186	Transcriptional regulator
C1192_RS17060	COG3734	2-keto-3-deoxy-galactonokinase
C1192_RS17065	COG0800	Aldolase
C1192_RS17075	COG2271	Major facilitator Superfamily
C1192_RS17085	COG0823	Involved in the tonB-independent uptake of proteins
C1192_RS17090	COG5645	(Lipo)protein
C1192_RS17115	COG2149	membrane
C1192_RS17125	COG0641	radical SAM
C1192_RS17130	COG2814	Major facilitator Superfamily
C1192_RS17140	COG0028	Belongs to the TPP enzyme family
C1192_RS17145	COG0440	acetolactate synthase activity
C1192_RS17150	COG2197	response regulator
C1192_RS17155	COG3851	Histidine kinase
C1192_RS17160	COG2271	Major facilitator Superfamily
C1192_RS17165	COG2271	Major facilitator Superfamily
C1192_RS17175	COG2252	PERMEase
C1192_RS17200	COG1464	Belongs to the NlpA lipoprotein family
C1192_RS17205	COG0697	spore germination
C1192_RS17235	COG4372	Transposase
C1192_RS17240	COG3436	PFAM IS66 Orf2 family protein
C1192_RS17315	COG0582	viral genome integration into host DNA
C1192_RS17325	COG4372	Transposase
C1192_RS17330	COG3436	PFAM IS66 Orf2 family protein
C1192_RS17340	COG2211	Major facilitator Superfamily
C1192_RS17350	COG3328	transposase activity
C1192_RS17355	COG2982	Protein involved in outer membrane biogenesis
C1192_RS17360	COG2233	PERMEase
C1192_RS17365	COG0786	glutamate:sodium symporter activity
C1192_RS17370	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C1192_RS17375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1192_RS17380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C1192_RS17390	COG0194	GDP metabolic process
C1192_RS17405	COG2860	membrane
C1192_RS17410	COG1561	YicC-like family, N-terminal region
C1192_RS17435	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C1192_RS17465	COG1519	Transferase
C1192_RS17470	COG0859	PFAM glycosyl transferase family 9
C1192_RS17475	COG0438	transferase activity, transferring glycosyl groups
C1192_RS17480	COG0515	serine threonine protein kinase
C1192_RS17490	COG0438	transferase activity, transferring glycosyl groups
C1192_RS17495	COG1442	glycosyl transferase family 8
C1192_RS17500	COG1442	glycosyl transferase family 8
C1192_RS17505	COG3642	lipopolysaccharide core region biosynthetic process
C1192_RS17525	COG0859	PFAM glycosyl transferase family 9
C1192_RS17530	COG0859	PFAM glycosyl transferase family 9
C1192_RS17540	COG0156	8-amino-7-oxononanoate synthase activity
C1192_RS17550	COG1216	Glycosyl transferase, family 2
C1192_RS17555	COG2861	carbohydrate metabolic process
C1192_RS17560	COG4942	peptidase
C1192_RS17575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1192_RS17580	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C1192_RS17595	COG1045	serine acetyltransferase
C1192_RS17600	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C1192_RS17610	COG2186	Transcriptional regulator
C1192_RS17615	COG1620	l-lactate permease
C1192_RS17620	COG5295	Hep Hag repeat protein
C1192_RS17640	COG3722	fumarate hydratase activity
C1192_RS17650	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1192_RS17650	COG2213	PTS system mannitol-specific
C1192_RS17660	COG1566	PFAM secretion protein HlyD family protein
C1192_RS17675	COG0625	glutathione transferase activity
C1192_RS17685	COG3276	selenocysteine insertion sequence binding
C1192_RS17690	COG1454	alcohol dehydrogenase
C1192_RS17695	COG1012	belongs to the aldehyde dehydrogenase family
C1192_RS17740	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C1192_RS17760	COG2258	MOSC domain
C1192_RS17765	COG2205	protein histidine kinase activity
C1192_RS17770	COG0745	RESPONSE REGULATOR receiver
C1192_RS17775	COG3678	ATP-independent chaperone mediated protein folding
C1192_RS17790	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C1192_RS17810	COG3152	Membrane
C1192_RS17815	COG3691	Protein conserved in bacteria
C1192_RS17820	COG0589	response to stress
C1192_RS17830	COG1494	fructose-1,6-bisphosphatase
C1192_RS17840	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C1192_RS17865	COG1575	Belongs to the MenA family. Type 1 subfamily
C1192_RS17880	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C1192_RS17885	COG1609	Transcriptional regulator
C1192_RS17890	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C1192_RS17925	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C1192_RS17935	COG0626	cystathionine gamma-synthase activity
C1192_RS17940	COG0527	aspartate kinase activity
C1192_RS17940	COG0460	homoserine dehydrogenase
C1192_RS17945	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C1192_RS17955	COG0697	spore germination
C1192_RS17960	COG3738	Protein conserved in bacteria
C1192_RS17965	COG0371	Dehydrogenase
C1192_RS17970	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C1192_RS17975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1192_RS17975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C1192_RS17975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1192_RS17980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1192_RS17985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1192_RS17990	COG1882	Formate acetyltransferase
C1192_RS17995	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C1192_RS18000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1192_RS18005	COG2207	Transcriptional regulator
C1192_RS18010	COG2194	sulfuric ester hydrolase activity
C1192_RS18030	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C1192_RS18045	COG4948	Mandelate Racemase Muconate Lactonizing
C1192_RS18050	COG2271	Major facilitator Superfamily
C1192_RS18055	COG0583	DNA-binding transcription factor activity
C1192_RS18065	COG1473	amidohydrolase
C1192_RS18070	COG0477	Major facilitator Superfamily
C1192_RS18090	COG4206	TonB-dependent receptor
C1192_RS18125	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C1192_RS18125	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C1192_RS18130	COG3385	transposase activity
C1192_RS18175	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C1192_RS18180	COG0250	Participates in transcription elongation, termination and antitermination
C1192_RS18225	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C1192_RS18235	COG2104	thiamine diphosphate biosynthetic process
C1192_RS18240	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C1192_RS18275	COG3068	Protein conserved in bacteria
C1192_RS18290	COG3678	ATP-independent chaperone mediated protein folding
C1192_RS18300	COG4191	Histidine kinase
C1192_RS18305	COG2204	response regulator
C1192_RS18310	COG0151	Belongs to the GarS family
C1192_RS18355	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C1192_RS18360	COG2224	Isocitrate lyase
C1192_RS18370	COG1414	Transcriptional regulator
C1192_RS18375	COG0646	methionine synthase
C1192_RS18375	COG1410	methionine synthase
C1192_RS18380	COG1283	sodium-dependent phosphate transmembrane transporter activity
C1192_RS18390	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C1192_RS18430	COG1187	pseudouridine synthase activity
C1192_RS18440	COG3541	Predicted nucleotidyltransferase
C1192_RS18445	COG0527	aspartate kinase activity
C1192_RS18470	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1192_RS18485	COG3833	ABC-type maltose transport systems, permease component
C1192_RS18490	COG1175	transmembrane transport
C1192_RS18495	COG2182	Extracellular solute-binding protein
C1192_RS18505	COG3842	ATPase activity
C1192_RS18535	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C1192_RS18545	COG0534	Mate efflux family protein
C1192_RS18550	COG3237	CsbD-like
C1192_RS18555	COG0735	belongs to the Fur family
C1192_RS18560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C1192_RS18570	COG3344	reverse transcriptase
C1192_RS18575	COG0604	alcohol dehydrogenase
C1192_RS18580	COG1053	succinate dehydrogenase
C1192_RS18585	COG0477	Major facilitator Superfamily
C1192_RS18590	COG1024	Enoyl-CoA hydratase
C1192_RS18605	COG0305	Participates in initiation and elongation during chromosome replication
C1192_RS18610	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C1192_RS18615	COG1448	Aminotransferase
C1192_RS18620	COG3700	Belongs to the class B bacterial acid phosphatase family
C1192_RS18625	COG0432	Pfam Uncharacterised protein family UPF0047
C1192_RS18630	COG2315	Protein conserved in bacteria
C1192_RS18635	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C1192_RS18640	COG0629	single-stranded DNA binding
C1192_RS18655	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C1192_RS18660	COG2207	Transcriptional regulator
C1192_RS18665	COG0789	Transcriptional regulator
C1192_RS18675	COG2252	PERMEase
C1192_RS18680	COG0025	NhaP-type Na H and K H
C1192_RS18690	COG3162	membrane
C1192_RS18695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1192_RS18710	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C1192_RS18715	COG0437	4 iron, 4 sulfur cluster binding
C1192_RS18720	COG3301	Polysulphide reductase, NrfD
C1192_RS18725	COG1138	Cytochrome C-type biogenesis protein
C1192_RS18730	COG3088	subunit of a heme lyase
C1192_RS18735	COG4235	cytochrome complex assembly
C1192_RS18745	COG1301	dicarboxylic acid transport
C1192_RS18755	COG4608	Belongs to the ABC transporter superfamily
C1192_RS18765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1192_RS18770	COG0601	transmembrane transport
C1192_RS18790	COG1289	transmembrane transporter activity
C1192_RS18795	COG3328	transposase activity
C1192_RS18800	COG3385	transposase activity
C1192_RS18815	COG3328	transposase activity
C1192_RS18825	COG3385	transposase activity
C1192_RS18830	COG2105	PFAM AIG2 family protein
C1192_RS18835	COG2911	Protein conserved in bacteria
C1192_RS18840	COG0729	surface antigen
C1192_RS18855	COG1253	flavin adenine dinucleotide binding
C1192_RS18865	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C1192_RS18870	COG1218	3'(2'),5'-bisphosphate nucleotidase
C1192_RS18875	COG0737	Belongs to the 5'-nucleotidase family
C1192_RS18880	COG1733	regulation of RNA biosynthetic process
C1192_RS18885	COG0702	epimerase
C1192_RS18890	COG0697	spore germination
C1192_RS18910	COG1113	amino acid transport
C1192_RS18915	COG0545	Peptidyl-prolyl cis-trans isomerase
C1192_RS18925	COG3061	Opacity-associated protein A
C1192_RS18930	COG1309	transcriptional regulator
C1192_RS18945	COG1024	Enoyl-CoA hydratase
C1192_RS18950	COG4670	ketone body catabolic process
C1192_RS18955	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C1192_RS18960	COG2271	Major facilitator Superfamily
C1192_RS18970	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C1192_RS19010	COG3414	Phosphotransferase system galactitol-specific IIB component
C1192_RS19015	COG3037	sugar-specific permease SgaT UlaA
C1192_RS19030	COG1073	alpha beta
C1192_RS19035	COG3650	response to hydrogen peroxide
C1192_RS19050	COG0754	glutathionylspermidine amidase activity
C1192_RS19070	COG1842	Phage shock protein A
C1192_RS19075	COG3789	protein conserved in bacteria
C1192_RS19080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1192_RS19085	COG0557	exoribonuclease II activity
C1192_RS19100	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C1192_RS19105	COG0330	HflC and HflK could
C1192_RS19110	COG0330	HflC and HflK could
C1192_RS19115	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C1192_RS19135	COG0860	N-Acetylmuramoyl-L-alanine amidase
C1192_RS19140	COG0802	atpase or kinase
C1192_RS19145	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C1192_RS19145	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C1192_RS19185	COG3264	Mechanosensitive ion channel
C1192_RS19185	COG1511	domain protein
C1192_RS19200	COG0531	amino acid
C1192_RS19210	COG1053	succinate dehydrogenase
C1192_RS19215	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C1192_RS19230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C1192_RS19235	COG3040	lipid binding
C1192_RS19240	COG2076	Multidrug Resistance protein
C1192_RS19245	COG5510	response to toxic substance
C1192_RS19250	COG5510	response to toxic substance
C1192_RS19260	COG1509	lysine 2,3-aminomutase activity
C1192_RS19285	COG0531	amino acid
C1192_RS19290	COG3030	protein affecting phage T7 exclusion by the F plasmid
C1192_RS19295	COG1027	Aspartate ammonia-lyase
C1192_RS19300	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C1192_RS19310	COG4232	protein-disulfide reductase activity
C1192_RS19315	COG1309	transcriptional regulator
C1192_RS19325	COG3710	Transcriptional regulator
C1192_RS19335	COG0531	amino acid
C1192_RS19340	COG1982	Orn Lys Arg decarboxylase major
C1192_RS19345	COG3104	oligopeptide transport
C1192_RS19350	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C1192_RS19365	COG2388	GCN5-related N-acetyl-transferase
C1192_RS19370	COG3592	Divergent 4Fe-4S mono-cluster
C1192_RS19375	COG3290	protein histidine kinase activity
C1192_RS19380	COG4565	transcriptional regulatory protein
C1192_RS19390	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C1192_RS19395	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C1192_RS19395	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C1192_RS19400	COG3647	Membrane
C1192_RS19410	COG3328	transposase activity
C1192_RS19420	COG1486	melibiose metabolic process
C1192_RS19425	COG2169	Transcriptional regulator
C1192_RS19430	COG1982	Orn Lys Arg decarboxylase major
C1192_RS19435	COG2207	Transcriptional regulator
C1192_RS19440	COG0531	amino acid
C1192_RS19445	COG2194	sulfuric ester hydrolase activity
C1192_RS19450	COG0745	RESPONSE REGULATOR receiver
C1192_RS19455	COG0642	Histidine kinase
C1192_RS19465	COG0477	Major facilitator Superfamily
C1192_RS19485	COG2824	Alkylphosphonate utilization operon protein PhnA
C1192_RS19490	COG2764	glyoxalase bleomycin resistance protein dioxygenase
C1192_RS19505	COG1737	Transcriptional regulator
C1192_RS19510	COG1879	ABC-type sugar transport system periplasmic component
C1192_RS19515	COG1129	ABC transporter
C1192_RS19520	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1192_RS19525	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C1192_RS19530	COG1940	carbohydrate kinase activity
C1192_RS19535	COG2015	COG2015, Alkyl sulfatase and related hydrolases
C1192_RS19545	COG1566	PFAM secretion protein HlyD family protein
C1192_RS19550	COG3328	transposase activity
C1192_RS19555	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
C1192_RS19565	COG2731	YhcH YjgK YiaL family protein
C1192_RS19585	COG0251	oxidation-reduction process
C1192_RS19595	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C1192_RS19610	COG1609	Transcriptional regulator
C1192_RS19615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1192_RS19615	COG1263	PTS System
C1192_RS19620	COG0366	Alpha amylase catalytic
C1192_RS19625	COG1328	CTP reductase activity
C1192_RS19630	COG0602	queuosine metabolic process
C1192_RS19640	COG3077	Addiction module antitoxin, RelB DinJ family
C1192_RS19650	COG3783	Cytochrome b(562)
C1192_RS19655	COG0312	modulator of DNA gyrase
C1192_RS19665	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C1192_RS19680	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1192_RS19685	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1192_RS19690	COG1129	ABC transporter
C1192_RS19695	COG1879	ABC-type sugar transport system periplasmic component
C1192_RS19705	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C1192_RS19710	COG1263	PTS System
C1192_RS19710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1192_RS19710	COG2190	(PTS) system
C1192_RS19720	COG3385	transposase activity
C1192_RS19735	COG2375	cellular response to nickel ion
C1192_RS19740	COG1695	Transcriptional regulator
C1192_RS19745	COG0840	transmembrane signaling receptor activity
C1192_RS19760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1192_RS19770	COG1609	Transcriptional regulator
C1192_RS19775	COG3250	beta-galactosidase activity
C1192_RS19780	COG2731	YhcH YjgK YiaL family protein
C1192_RS19785	COG0531	amino acid
C1192_RS19800	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1192_RS19800	COG1902	pentaerythritol trinitrate reductase activity
C1192_RS19810	COG1451	nucleotide metabolic process
C1192_RS19815	COG2949	membrane
C1192_RS19820	COG0673	inositol 2-dehydrogenase activity
C1192_RS19825	COG0861	Integral membrane protein TerC family
C1192_RS19830	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C1192_RS19840	COG2721	sulfolactate sulfo-lyase activity
C1192_RS19850	COG2271	Major facilitator Superfamily
C1192_RS19855	COG2186	Transcriptional regulator
C1192_RS19860	COG0586	Pfam SNARE associated Golgi protein
C1192_RS19870	COG1422	Protein of unknown function (DUF1090)
C1192_RS19875	COG4575	ribosome binding
C1192_RS19880	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
C1192_RS19890	COG2259	Doxx family
C1192_RS19895	COG0435	Glutathione S-transferase
C1192_RS19900	COG3152	Membrane
C1192_RS19905	COG0583	DNA-binding transcription factor activity
C1192_RS19910	COG1741	Belongs to the pirin family
C1192_RS19925	COG0814	amino acid
C1192_RS19930	COG1760	l-serine dehydratase
C1192_RS19935	COG0251	oxidation-reduction process
C1192_RS19940	COG1882	Formate acetyltransferase
C1192_RS19945	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C1192_RS19955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C1192_RS19960	COG0583	DNA-binding transcription factor activity
C1192_RS19975	COG1929	Belongs to the glycerate kinase type-1 family
C1192_RS19980	COG2084	Dehydrogenase
C1192_RS19985	COG3836	Belongs to the HpcH HpaI aldolase family
C1192_RS19990	COG2271	Major facilitator Superfamily
C1192_RS19995	COG2721	sulfolactate sulfo-lyase activity
C1192_RS20000	COG1349	DNA-binding transcription factor activity
C1192_RS20015	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1192_RS20025	COG3716	PTS system mannose fructose sorbose family IID component
C1192_RS20030	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1192_RS20035	COG2222	sugar isomerase
C1192_RS20045	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1192_RS20055	COG3716	PTS system mannose fructose sorbose family IID component
C1192_RS20060	COG0363	glucosamine-6-phosphate deaminase activity
C1192_RS20065	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C1192_RS20070	COG3107	peptidoglycan biosynthetic process
C1192_RS20090	COG2823	Periplasmic or secreted lipoprotein
C1192_RS20095	COG3328	transposase activity
C1192_RS20100	COG0433	COG0433 Predicted ATPase
C1192_RS20105	COG1064	alcohol dehydrogenase
C1192_RS20120	COG0795	lipopolysaccharide-transporting ATPase activity
C1192_RS20125	COG0795	lipopolysaccharide-transporting ATPase activity
C1192_RS20135	COG2927	DNA polymerase III (CHI subunit)
C1192_RS20140	COG0525	valine-tRNA ligase activity
C1192_RS20150	COG3385	transposase activity
C1192_RS20160	COG0456	acetyltransferase
C1192_RS20165	COG3328	transposase activity
C1192_RS20170	COG3385	transposase activity
C1192_RS20175	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C1192_RS20185	COG0358	DNA primase activity
C1192_RS20190	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C1192_RS20210	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C1192_RS20225	COG4991	sh3 domain protein
C1192_RS20235	COG3025	triphosphatase activity
C1192_RS20255	COG2268	Band 7 protein
C1192_RS20290	COG3384	dioxygenase
C1192_RS20300	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C1192_RS20310	COG0754	glutathionylspermidine amidase activity
C1192_RS20325	COG1538	Outer membrane efflux protein
C1192_RS20330	COG0494	nUDIX hydrolase
C1192_RS20335	COG3151	Protein conserved in bacteria
C1192_RS20340	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C1192_RS20345	COG3150	esterase
C1192_RS20350	COG0187	DNA topoisomerase II activity
C1192_RS20355	COG4774	siderophore transport
C1192_RS20360	COG1120	ATPase activity
C1192_RS20365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1192_RS20370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1192_RS20380	COG1737	Transcriptional regulator
C1192_RS20385	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C1192_RS20390	COG2249	NAD(P)H dehydrogenase (quinone) activity
C1192_RS20395	COG0642	Histidine kinase
C1192_RS20400	COG0745	RESPONSE REGULATOR receiver
C1192_RS20405	COG3111	PFAM Bacterial OB fold (BOF) protein
C1192_RS20410	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C1192_RS20420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C1192_RS20425	COG0204	Acyl-transferase
C1192_RS20430	COG2132	Multicopper oxidase
C1192_RS20435	COG1032	radical SAM domain protein
C1192_RS20440	COG4238	major outer membrane lipoprotein
C1192_RS20450	COG0656	L-ascorbic acid biosynthetic process
C1192_RS20455	COG1979	alcohol dehydrogenase
C1192_RS20460	COG2207	Transcriptional regulator
C1192_RS20465	COG0586	Pfam SNARE associated Golgi protein
C1192_RS20470	COG0626	cystathionine gamma-synthase activity
C1192_RS20480	COG0811	peptide transport
C1192_RS20485	COG0848	biopolymer transport protein
C1192_RS20500	COG0667	Aldo Keto reductase
C1192_RS20520	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C1192_RS20525	COG0437	4 iron, 4 sulfur cluster binding
C1192_RS20530	COG5557	Pfam Polysulphide reductase, NrfD
C1192_RS20535	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C1192_RS20540	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C1192_RS20545	COG1773	rubredoxin
C1192_RS20555	COG0298	carbon dioxide binding
C1192_RS20560	COG0625	glutathione transferase activity
C1192_RS20565	COG0754	glutathionylspermidine amidase activity
C1192_RS20575	COG0306	phosphate transporter
C1192_RS20580	COG0306	phosphate transporter
C1192_RS20585	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C1192_RS20590	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C1192_RS20595	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C1192_RS20610	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C1192_RS20615	COG0795	lipopolysaccharide-transporting ATPase activity
C1192_RS20625	COG0156	8-amino-7-oxononanoate synthase activity
C1192_RS20630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C1192_RS20640	COG3385	transposase activity
C1192_RS20650	COG3436	PFAM IS66 Orf2 family protein
C1192_RS20655	COG4372	Transposase
C1192_RS20685	COG2885	chlorophyll binding
C1192_RS20725	COG1811	Na channel or pump
C1192_RS20730	COG1982	Orn Lys Arg decarboxylase major
C1192_RS20735	COG2211	Major facilitator Superfamily
C1192_RS20750	COG1194	a g-specific adenine glycosylase
C1192_RS20765	COG3171	Protein conserved in bacteria
C1192_RS20775	COG0252	asparaginase activity
C1192_RS20785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C1192_RS20800	COG0762	integral membrane protein
C1192_RS20805	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C1192_RS20810	COG2805	Type II/IV secretion system protein
C1192_RS20825	COG0189	ligase activity
C1192_RS20830	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C1192_RS20835	COG2356	endonuclease I
C1192_RS20870	COG1166	arginine decarboxylase activity
C1192_RS20885	COG0501	Belongs to the peptidase M48B family
C1192_RS20890	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C1192_RS20895	COG0330	HflC and HflK could
C1192_RS20905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1192_RS20910	COG2213	PTS system mannitol-specific
C1192_RS20915	COG1063	alcohol dehydrogenase
C1192_RS20920	COG1494	fructose-1,6-bisphosphatase
C1192_RS20930	COG1072	(Pantothenic acid kinase))
C1192_RS20940	COG1122	ATPase activity
C1192_RS20955	COG3328	transposase activity
C1192_RS20960	COG3385	transposase activity
C1192_RS20985	COG0191	fructose-bisphosphate aldolase activity
C1192_RS20990	COG0668	transmembrane transport
C1192_RS21005	COG1279	arginine transmembrane transporter activity
C1192_RS21010	COG2968	Membrane
C1192_RS21015	COG0583	DNA-binding transcription factor activity
C1192_RS21020	COG0427	acetyl-CoA hydrolase
C1192_RS21025	COG1024	Enoyl-CoA hydratase
C1192_RS21030	COG1703	isobutyryl-CoA mutase activity
C1192_RS21035	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C1192_RS21035	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C1192_RS21050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1192_RS21055	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C1192_RS21080	COG0006	proline dipeptidase activity
C1192_RS21085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1192_RS21090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1192_RS21110	COG2723	6-phospho-beta-galactosidase activity
C1192_RS21120	COG1272	protein, Hemolysin III
C1192_RS21135	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C1192_RS21145	COG0716	FMN binding
C1192_RS21150	COG4974	Belongs to the 'phage' integrase family
C1192_RS21155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C1192_RS21160	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C1192_RS21170	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C1192_RS21175	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C1192_RS21185	COG2233	PERMEase
C1192_RS21195	COG0493	'glutamate synthase
C1192_RS21195	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1192_RS21200	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1192_RS21205	COG2252	PERMEase
C1192_RS21210	COG0402	S-adenosylhomocysteine deaminase activity
C1192_RS21215	COG2233	PERMEase
C1192_RS21220	COG2080	2 iron, 2 sulfur cluster binding
C1192_RS21220	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C1192_RS21225	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C1192_RS21235	COG0493	'glutamate synthase
C1192_RS21235	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1192_RS21240	COG2068	MobA-Related Protein
C1192_RS21245	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C1192_RS21255	COG0549	Belongs to the carbamate kinase family
C1192_RS21265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1192_RS21270	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C1192_RS21275	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C1192_RS21280	COG3829	transcription factor binding
C1192_RS21285	COG2080	2 iron, 2 sulfur cluster binding
C1192_RS21290	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C1192_RS21295	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C1192_RS21300	COG4942	peptidase
C1192_RS21325	COG3710	Transcriptional regulator
C1192_RS21335	COG0814	amino acid
C1192_RS21340	COG0183	Belongs to the thiolase family
C1192_RS21355	COG1028	Short-chain dehydrogenase reductase Sdr
C1192_RS21360	COG2814	Major facilitator Superfamily
C1192_RS21365	COG1794	racemase activity, acting on amino acids and derivatives
C1192_RS21370	COG0583	DNA-binding transcription factor activity
C1192_RS21380	COG1609	Transcriptional regulator
C1192_RS21405	COG0667	Aldo Keto reductase
C1192_RS21415	COG0861	Integral membrane protein TerC family
C1192_RS21430	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
C1192_RS21450	COG4795	General secretion pathway protein
C1192_RS21460	COG4967	type IV pilus modification protein PilV
C1192_RS21465	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C1192_RS21475	COG1074	ATP-dependent DNA helicase activity
C1192_RS21480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C1192_RS21485	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C1192_RS21485	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C1192_RS21495	COG0860	N-Acetylmuramoyl-L-alanine amidase
C1192_RS21535	COG3344	reverse transcriptase
C1192_RS21585	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C1192_RS21590	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C1192_RS21595	COG2166	iron-sulfur cluster assembly
C1192_RS21600	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C1192_RS21610	COG0583	DNA-binding transcription factor activity
C1192_RS21615	COG2363	Small membrane protein
C1192_RS21625	COG1349	DNA-binding transcription factor activity
C1192_RS21635	COG1070	Carbohydrate kinase
C1192_RS21645	COG1129	ABC transporter
C1192_RS21650	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1192_RS21655	COG1609	Transcriptional regulator
C1192_RS21660	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C1192_RS21670	COG0235	Class ii aldolase
C1192_RS21675	COG1454	alcohol dehydrogenase
C1192_RS21685	COG1760	l-serine dehydratase
C1192_RS21690	COG0814	amino acid
C1192_RS21695	COG1611	Belongs to the LOG family
C1192_RS21710	COG3098	single-species biofilm formation
C1192_RS21715	COG0564	pseudouridine synthase activity
C1192_RS21720	COG0716	FMN binding
C1192_RS21725	COG2205	protein histidine kinase activity
C1192_RS21725	COG3850	Histidine kinase
C1192_RS21725	COG4999	Histidine kinase
C1192_RS21725	COG3437	response regulator, receiver
C1192_RS21730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C1192_RS21735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C1192_RS21740	COG3956	TIGRFAM MazG family protein
C1192_RS21755	COG3385	transposase activity
C1192_RS21765	COG3328	transposase activity
C1192_RS21780	COG0602	queuosine metabolic process
C1192_RS21790	COG1070	Carbohydrate kinase
C1192_RS21795	COG2223	nitrite transmembrane transporter activity
C1192_RS21800	COG1028	Short-chain dehydrogenase reductase Sdr
C1192_RS21805	COG0277	FAD linked oxidase domain protein
C1192_RS21810	COG0477	Major facilitator Superfamily
C1192_RS21815	COG2086	electron transfer activity
C1192_RS21825	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C1192_RS21830	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C1192_RS21835	COG0644	oxidoreductase
C1192_RS21840	COG0720	synthase
C1192_RS21850	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C1192_RS21870	COG2234	aminopeptidase activity
C1192_RS21925	COG4942	peptidase
C1192_RS21925	COG1388	LysM domain
C1192_RS21930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C1192_RS21935	COG3344	reverse transcriptase
C1192_RS21940	COG3328	transposase activity
C1192_RS21945	COG3622	Belongs to the hyi family
C1192_RS21950	COG0235	Class ii aldolase
C1192_RS21960	COG2084	Dehydrogenase
C1192_RS21965	COG1349	DNA-binding transcription factor activity
C1192_RS21995	COG3604	Transcriptional regulator
C1192_RS22000	COG0309	Hydrogenase expression formation protein (HypE)
C1192_RS22005	COG0409	Hydrogenase expression formation protein
C1192_RS22010	COG0298	carbon dioxide binding
C1192_RS22015	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C1192_RS22020	COG0375	protein maturation
C1192_RS22030	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1192_RS22035	COG0651	ATP synthesis coupled electron transport
C1192_RS22040	COG0650	Formate hydrogenlyase subunit 4
C1192_RS22045	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C1192_RS22045	COG3261	NADH dehydrogenase
C1192_RS22050	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C1192_RS22055	COG3260	NADH ubiquinone oxidoreductase 20
C1192_RS22065	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C1192_RS22080	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1192_RS22085	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
C1192_RS22110	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C1192_RS22110	COG0517	IMP dehydrogenase activity
C1192_RS22115	COG1349	DNA-binding transcription factor activity
C1192_RS22120	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1192_RS22125	COG1028	Short-chain dehydrogenase reductase Sdr
C1192_RS22135	COG3732	PTS system glucitol sorbitol-specific
C1192_RS22140	COG3730	PTS system glucitol sorbitol-specific
C1192_RS22145	COG2951	lytic endotransglycosylase activity
C1192_RS22155	COG1546	Belongs to the CinA family
C1192_RS22175	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C1192_RS22200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1192_RS22205	COG1238	metal cluster binding
C1192_RS22225	COG2814	Major facilitator Superfamily
C1192_RS22230	COG1566	PFAM secretion protein HlyD family protein
C1192_RS22240	COG1846	Transcriptional regulator
C1192_RS22250	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C1192_RS22255	COG2814	Major facilitator Superfamily
C1192_RS22260	COG3385	transposase activity
C1192_RS22265	COG3328	transposase activity
C1192_RS22275	COG2113	Glycine betaine
C1192_RS22280	COG4176	ABC-type proline glycine betaine transport system permease component
C1192_RS22285	COG4175	Glycine betaine
C1192_RS22295	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1192_RS22300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1192_RS22310	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C1192_RS22320	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C1192_RS22330	COG4575	ribosome binding
C1192_RS22345	COG2916	Histone family protein nucleoid-structuring protein H-NS
C1192_RS22350	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1192_RS22355	COG0640	Transcriptional regulator
C1192_RS22360	COG0401	homolog of Blt101
C1192_RS22365	COG1652	LysM domain
C1192_RS22370	COG1802	Transcriptional regulator
C1192_RS22375	COG1113	amino acid transport
C1192_RS22380	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C1192_RS22385	COG1012	belongs to the aldehyde dehydrogenase family
C1192_RS22415	COG2867	negative regulation of translational initiation
C1192_RS22425	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1192_RS22430	COG0497	DNA recombination
C1192_RS22450	COG4536	flavin adenine dinucleotide binding
C1192_RS22455	COG4137	Cytochrome C assembly protein
C1192_RS22460	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C1192_RS22485	COG2885	chlorophyll binding
C1192_RS22490	COG2199	diguanylate cyclase activity
C1192_RS22505	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C1192_RS22510	COG0287	Prephenate dehydrogenase
C1192_RS22510	COG1605	Chorismate mutase
C1192_RS22515	COG0077	Prephenate dehydratase
C1192_RS22515	COG1605	Chorismate mutase
C1192_RS22525	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C1192_RS22530	COG3385	transposase activity
C1192_RS22535	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1192_RS22540	COG0564	pseudouridine synthase activity
C1192_RS22550	COG0542	response to heat
C1192_RS22580	COG0477	Major facilitator Superfamily
C1192_RS22585	COG5544	Lipoprotein
C1192_RS22590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1192_RS22595	COG0045	succinate-CoA ligase (ADP-forming) activity
C1192_RS22595	COG1042	CoA-binding domain protein
C1192_RS22595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1192_RS22600	COG3148	PFAM DTW domain containing protein
C1192_RS22605	COG3118	belongs to the thioredoxin family
C1192_RS22615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1192_RS22630	COG0513	Belongs to the DEAD box helicase family
C1192_RS22640	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C1192_RS22645	COG1595	DNA-templated transcription, initiation
C1192_RS22650	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
C1192_RS22655	COG3026	antisigma factor binding
C1192_RS22660	COG3086	response to oxidative stress
C1192_RS22670	COG0681	Belongs to the peptidase S26 family
C1192_RS22695	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C1192_RS22710	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1192_RS22715	COG1737	Transcriptional regulator
C1192_RS22720	COG0560	Phosphoserine phosphatase
C1192_RS22740	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C1192_RS22740	COG0047	phosphoribosylformylglycinamidine synthase activity
C1192_RS22745	COG2205	protein histidine kinase activity
C1192_RS22750	COG3170	Tfp pilus assembly protein FimV
C1192_RS22755	COG2204	response regulator
C1192_RS22760	COG0347	Belongs to the P(II) protein family
C1192_RS22765	COG1017	nitric oxide dioxygenase activity
C1192_RS22765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C1192_RS22780	COG1940	carbohydrate kinase activity
C1192_RS22790	COG1879	ABC-type sugar transport system periplasmic component
C1192_RS22800	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1192_RS22810	COG2017	converts alpha-aldose to the beta-anomer
C1192_RS22815	COG2259	Doxx family
C1192_RS22825	COG3711	transcriptional antiterminator
C1192_RS22830	COG1073	alpha beta
C1192_RS22835	COG0483	inositol monophosphate 1-phosphatase activity
C1192_RS22855	COG0822	iron-sulfur transferase activity
C1192_RS22875	COG0633	Ferredoxin
C1192_RS22880	COG2975	iron-sulfur cluster assembly
C1192_RS22895	COG2897	thiosulfate sulfurtransferase activity
C1192_RS22900	COG2373	Large extracellular alpha-helical protein
C1192_RS22905	COG4953	penicillin-binding protein 1C
C1192_RS22940	COG2976	Protein conserved in bacteria
C1192_RS22955	COG1645	bacterial-type flagellum-dependent swarming motility
C1192_RS22965	COG0516	GMP reductase activity
C1192_RS22965	COG0517	IMP dehydrogenase activity
C1192_RS22980	COG3133	Outer membrane lipoprotein
C1192_RS23000	COG2200	EAL domain
C1192_RS23005	COG0248	Ppx GppA phosphatase
C1192_RS23010	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C1192_RS23015	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C1192_RS23030	COG2233	PERMEase
C1192_RS23040	COG1393	Belongs to the ArsC family
C1192_RS23045	COG4783	chaperone-mediated protein folding
C1192_RS23055	COG0628	permease
C1192_RS23060	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C1192_RS23065	COG2716	regulation of RNA biosynthetic process
C1192_RS23075	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C1192_RS23085	COG2321	neutral zinc metallopeptidase
C1192_RS23090	COG1444	tRNA N-acetyltransferase activity
C1192_RS23095	COG0400	carboxylic ester hydrolase activity
C1192_RS23110	COG1393	Belongs to the ArsC family
C1192_RS23120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1192_RS23135	COG3850	Histidine kinase
C1192_RS23140	COG0493	'glutamate synthase
C1192_RS23140	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1192_RS23150	COG5342	invasion associated locus B
C1192_RS23155	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C1192_RS23160	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C1192_RS23165	COG0280	phosphate acetyltransferase
C1192_RS23165	COG0281	malic enzyme
C1192_RS23170	COG4810	utilization protein
C1192_RS23175	COG4917	ethanolamine utilization protein
C1192_RS23180	COG4766	ethanolamine catabolic process
C1192_RS23185	COG4812	Cobalamin adenosyltransferase
C1192_RS23190	COG0280	phosphate acetyltransferase
C1192_RS23195	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C1192_RS23200	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
C1192_RS23205	COG1012	belongs to the aldehyde dehydrogenase family
C1192_RS23210	COG4820	ethanolamine utilization protein (EutJ)
C1192_RS23215	COG1454	alcohol dehydrogenase
C1192_RS23220	COG3192	ethanolamine utilization protein
C1192_RS23225	COG4819	ethanolamine utilization protein
C1192_RS23230	COG4303	Ethanolamine ammonia lyase large subunit
C1192_RS23240	COG4816	utilization protein
C1192_RS23245	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
C1192_RS23250	COG2207	Transcriptional regulator
C1192_RS23260	COG0860	N-Acetylmuramoyl-L-alanine amidase
C1192_RS23280	COG2837	iron assimilation
C1192_RS23290	COG1028	Short-chain dehydrogenase reductase Sdr
C1192_RS23295	COG4150	thiosulfate binding
C1192_RS23300	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C1192_RS23305	COG4208	sulfate ABC transporter
C1192_RS23310	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C1192_RS23315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C1192_RS23320	COG3831	ATPase activity
C1192_RS23320	COG4884	unkown
C1192_RS23335	COG3328	transposase activity
C1192_RS23340	COG3385	transposase activity
C1192_RS23355	COG3328	transposase activity
C1192_RS23365	COG2190	(PTS) system
C1192_RS23370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C1192_RS23375	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1192_RS23380	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C1192_RS23405	COG3530	Putative quorum-sensing-regulated virulence factor
C1192_RS23410	COG0385	Bile acid
C1192_RS23415	COG0583	DNA-binding transcription factor activity
C1192_RS23425	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C1192_RS23430	COG2211	Major facilitator Superfamily
C1192_RS23440	COG0583	DNA-binding transcription factor activity
C1192_RS23465	COG3415	Transposase
C1192_RS23470	COG3415	Transposase
C1192_RS23485	COG2200	EAL domain
C1192_RS23485	COG2199	diguanylate cyclase activity
C1192_RS23490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C1192_RS23515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1192_RS23520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1192_RS23525	COG0006	proline dipeptidase activity
C1192_RS23530	COG1363	Peptidase, m42
C1192_RS23540	COG2207	Transcriptional regulator
C1192_RS23545	COG3279	Response regulator of the LytR AlgR family
C1192_RS23550	COG3275	phosphorelay sensor kinase activity
C1192_RS23560	COG0436	Aminotransferase
C1192_RS23570	COG1560	Kdo2-lipid A biosynthetic process
C1192_RS23630	COG3723	Recombinational DNA repair protein, rece pathway
C1192_RS23685	COG0305	Participates in initiation and elongation during chromosome replication
C1192_RS23755	COG3772	lysozyme
C1192_RS23765	COG3646	Phage regulatory protein
C1192_RS23790	COG1783	phage Terminase large subunit
C1192_RS23885	COG3328	transposase activity
C1192_RS24040	COG3328	transposase activity
C1192_RS24070	COG2161	toxin-antitoxin pair type II binding
C1192_RS24075	COG4115	mRNA cleavage
C1192_RS24085	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C1192_RS24115	COG2165	general secretion pathway protein
C1192_RS24120	COG1459	type II secretion system
C1192_RS24125	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C1192_RS24135	COG3031	protein transport across the cell outer membrane
C1192_RS24145	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C1192_RS24150	COG3064	Membrane
C1192_RS24345	COG4372	Transposase
C1192_RS24350	COG3436	PFAM IS66 Orf2 family protein
C1192_RS24435	COG3436	PFAM IS66 Orf2 family protein
C1192_RS24440	COG4372	Transposase
C1192_RS24485	COG3328	transposase activity
C1192_RS24500	COG3385	transposase activity
C1192_RS24510	COG3436	PFAM IS66 Orf2 family protein
C1192_RS24515	COG4372	Transposase
C1192_RS24650	COG3328	transposase activity
C1192_RS24675	COG3708	Transcriptional regulator
C1192_RS24675	COG2207	Transcriptional regulator
C1192_RS24725	COG3436	PFAM IS66 Orf2 family protein
C1192_RS24730	COG4372	Transposase
C1192_RS24745	COG3385	transposase activity
C1192_RS24755	COG4372	Transposase
C1192_RS24760	COG3436	PFAM IS66 Orf2 family protein
C1192_RS24785	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C1192_RS24805	COG4932	domain protein
C1192_RS24805	COG1388	LysM domain
C1192_RS24805	COG2373	Large extracellular alpha-helical protein
C1192_RS24825	COG3328	transposase activity
C1192_RS24830	COG3385	transposase activity
C1192_RS24855	COG3436	PFAM IS66 Orf2 family protein
C1192_RS24860	COG4372	Transposase