locus-tag	class	description
H9Q80_RS00010	COG3716	PTS system mannose fructose sorbose family IID component
H9Q80_RS00020	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS00025	COG2207	Transcriptional regulator
H9Q80_RS00040	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q80_RS00040	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS00045	COG2222	sugar isomerase
H9Q80_RS00080	COG0391	Required for morphogenesis under gluconeogenic growth conditions
H9Q80_RS00085	COG1660	Displays ATPase and GTPase activities
H9Q80_RS00115	COG3344	reverse transcriptase
H9Q80_RS00145	COG4193	domain, Protein
H9Q80_RS00280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9Q80_RS00280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9Q80_RS00330	COG0270	DNA (cytosine-5-)-methyltransferase activity
H9Q80_RS00335	COG0270	DNA (cytosine-5-)-methyltransferase activity
H9Q80_RS00365	COG4974	Belongs to the 'phage' integrase family
H9Q80_RS00370	COG0492	ferredoxin-NADP+ reductase activity
H9Q80_RS00375	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
H9Q80_RS00380	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
H9Q80_RS00385	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H9Q80_RS00395	COG1307	EDD domain protein, DegV family
H9Q80_RS00405	COG1523	belongs to the glycosyl hydrolase 13 family
H9Q80_RS00410	COG1842	Phage shock protein A
H9Q80_RS00420	COG1473	amidohydrolase
H9Q80_RS00425	COG0058	SHG alpha-glucan phosphorylase activity
H9Q80_RS00450	COG1696	Membrane protein involved in D-alanine export
H9Q80_RS00455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9Q80_RS00465	COG1215	transferase activity, transferring glycosyl groups
H9Q80_RS00465	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H9Q80_RS00470	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H9Q80_RS00485	COG1134	teichoic acid transport
H9Q80_RS00490	COG1682	transport, permease protein
H9Q80_RS00515	COG0457	Tetratricopeptide repeat
H9Q80_RS00515	COG0463	Glycosyl transferase, family 2
H9Q80_RS00535	COG0745	RESPONSE REGULATOR receiver
H9Q80_RS00540	COG2205	protein histidine kinase activity
H9Q80_RS00550	COG1136	(ABC) transporter
H9Q80_RS00565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H9Q80_RS00575	COG1131	(ABC) transporter
H9Q80_RS00585	COG1349	DNA-binding transcription factor activity
H9Q80_RS00590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9Q80_RS00595	COG0434	BtpA family
H9Q80_RS00610	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS00630	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS00640	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS00645	COG1447	Phosphotransferase system cellobiose-specific component IIA
H9Q80_RS00650	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS00680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9Q80_RS00700	COG2203	Gaf domain
H9Q80_RS00700	COG2199	diguanylate cyclase activity
H9Q80_RS00705	COG0534	Mate efflux family protein
H9Q80_RS00715	COG2188	Transcriptional regulator
H9Q80_RS00730	COG3711	transcriptional antiterminator
H9Q80_RS00735	COG1132	(ABC) transporter
H9Q80_RS00745	COG1846	Transcriptional regulator
H9Q80_RS00750	COG5002	protein histidine kinase activity
H9Q80_RS00760	COG0556	nucleotide-excision repair
H9Q80_RS00765	COG3409	Peptidoglycan-binding domain 1 protein
H9Q80_RS00765	COG0793	Belongs to the peptidase S41A family
H9Q80_RS00785	COG2177	Part of the ABC transporter FtsEX involved in
H9Q80_RS00790	COG2884	Cell division ATP-binding protein ftsE
H9Q80_RS00800	COG2177	Part of the ABC transporter FtsEX involved in
H9Q80_RS00805	COG2884	Cell division ATP-binding protein ftsE
H9Q80_RS00820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9Q80_RS00830	COG0653	protein targeting
H9Q80_RS00835	COG1278	Cold shock
H9Q80_RS00845	COG1278	Cold shock
H9Q80_RS00855	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
H9Q80_RS00870	COG0561	phosphatase activity
H9Q80_RS00880	COG0726	polysaccharide deacetylase
H9Q80_RS00885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS00885	COG2190	(PTS) system
H9Q80_RS00885	COG1263	PTS System
H9Q80_RS00890	COG0366	Alpha amylase catalytic
H9Q80_RS00895	COG0561	phosphatase activity
H9Q80_RS00900	COG1737	Transcriptional regulator
H9Q80_RS00905	COG1737	Transcriptional regulator
H9Q80_RS00915	COG0561	phosphatase activity
H9Q80_RS00920	COG5001	Diguanylate cyclase
H9Q80_RS00925	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H9Q80_RS00940	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H9Q80_RS00955	COG3655	Transcriptional regulator
H9Q80_RS00970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H9Q80_RS00970	COG0512	Glutamine amidotransferase of anthranilate synthase
H9Q80_RS00975	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H9Q80_RS00980	COG0134	indole-3-glycerol-phosphate synthase activity
H9Q80_RS00985	COG0135	phosphoribosylanthranilate isomerase activity
H9Q80_RS00990	COG0133	tryptophan synthase activity
H9Q80_RS01000	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H9Q80_RS01005	COG0517	IMP dehydrogenase activity
H9Q80_RS01005	COG1125	glycine betaine transport
H9Q80_RS01030	COG0683	leucine binding
H9Q80_RS01050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H9Q80_RS01055	COG1994	Peptidase M50
H9Q80_RS01070	COG1136	(ABC) transporter
H9Q80_RS01080	COG0745	RESPONSE REGULATOR receiver
H9Q80_RS01090	COG3300	MHYT domain
H9Q80_RS01090	COG5001	Diguanylate cyclase
H9Q80_RS01115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9Q80_RS01120	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
H9Q80_RS01125	COG1737	Transcriptional regulator
H9Q80_RS01135	COG3716	PTS system mannose fructose sorbose family IID component
H9Q80_RS01145	COG3716	PTS system mannose fructose sorbose family IID component
H9Q80_RS01165	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H9Q80_RS01175	COG0126	phosphoglycerate kinase activity
H9Q80_RS01180	COG2199	diguanylate cyclase activity
H9Q80_RS01190	COG3706	GGDEF domain
H9Q80_RS01195	COG0517	IMP dehydrogenase activity
H9Q80_RS01195	COG0516	GMP reductase activity
H9Q80_RS01200	COG0534	Mate efflux family protein
H9Q80_RS01220	COG1454	alcohol dehydrogenase
H9Q80_RS01225	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS01235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q80_RS01235	COG3711	transcriptional antiterminator
H9Q80_RS01245	COG0297	glycogen (starch) synthase activity
H9Q80_RS01250	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H9Q80_RS01260	COG1122	ATPase activity
H9Q80_RS01265	COG4120	Belongs to the binding-protein-dependent transport system permease family
H9Q80_RS01280	COG0640	Transcriptional regulator
H9Q80_RS01290	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H9Q80_RS01315	COG1960	acyl-CoA dehydrogenase activity
H9Q80_RS01350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9Q80_RS01360	COG0305	Participates in initiation and elongation during chromosome replication
H9Q80_RS01365	COG0359	binds to the 23S rRNA
H9Q80_RS01380	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H9Q80_RS01385	COG0629	single-stranded DNA binding
H9Q80_RS01390	COG0360	Binds together with S18 to 16S ribosomal RNA
H9Q80_RS01405	COG4279	zinc finger
H9Q80_RS01410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H9Q80_RS01470	COG1215	transferase activity, transferring glycosyl groups
H9Q80_RS01505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H9Q80_RS01555	COG0534	Mate efflux family protein
H9Q80_RS01575	COG2801	Transposase and inactivated derivatives
H9Q80_RS01580	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
H9Q80_RS01585	COG0006	proline dipeptidase activity
H9Q80_RS01605	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS01615	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS01620	COG1737	Transcriptional regulator
H9Q80_RS01625	COG4221	oxidoreductase activity
H9Q80_RS01635	COG2239	Acts as a magnesium transporter
H9Q80_RS01655	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H9Q80_RS01660	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H9Q80_RS01670	COG0280	phosphate acetyltransferase
H9Q80_RS01690	COG3022	response to hydroperoxide
H9Q80_RS01700	COG1316	TRANSCRIPTIONal
H9Q80_RS01730	COG1216	Glycosyl transferase, family 2
H9Q80_RS01730	COG1442	glycosyl transferase family 8
H9Q80_RS01740	COG0438	transferase activity, transferring glycosyl groups
H9Q80_RS01760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H9Q80_RS01770	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H9Q80_RS01780	COG2890	protein-(glutamine-N5) methyltransferase activity
H9Q80_RS01785	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H9Q80_RS01790	COG1435	thymidine kinase activity
H9Q80_RS01795	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
H9Q80_RS01800	COG1518	maintenance of DNA repeat elements
H9Q80_RS01805	COG1468	defense response to virus
H9Q80_RS01860	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H9Q80_RS01875	COG4447	cellulose binding
H9Q80_RS01890	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
H9Q80_RS01895	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H9Q80_RS01900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9Q80_RS01905	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H9Q80_RS01915	COG3290	protein histidine kinase activity
H9Q80_RS01925	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
H9Q80_RS01930	COG1074	ATP-dependent DNA helicase activity
H9Q80_RS01935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H9Q80_RS01945	COG2207	Transcriptional regulator
H9Q80_RS01945	COG3708	Transcriptional regulator
H9Q80_RS01970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9Q80_RS01975	COG0445	tRNA wobble uridine modification
H9Q80_RS01985	COG0534	Mate efflux family protein
H9Q80_RS01995	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H9Q80_RS02000	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
H9Q80_RS02005	COG0037	tRNA processing
H9Q80_RS02135	COG3728	DNA packaging
H9Q80_RS02135	COG5484	DNA packaging
H9Q80_RS02170	COG0629	single-stranded DNA binding
H9Q80_RS02210	COG0175	sulfate reduction
H9Q80_RS02265	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H9Q80_RS02305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H9Q80_RS02320	COG2207	Transcriptional regulator
H9Q80_RS02320	COG4753	response regulator
H9Q80_RS02325	COG2972	Histidine kinase
H9Q80_RS02365	COG3279	Response regulator of the LytR AlgR family
H9Q80_RS02380	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H9Q80_RS02385	COG3457	Alanine racemase
H9Q80_RS02390	COG0626	cystathionine gamma-synthase activity
H9Q80_RS02400	COG1735	metal-dependent hydrolase with the TIM-barrel fold
H9Q80_RS02420	COG2188	Transcriptional regulator
H9Q80_RS02435	COG0681	Belongs to the peptidase S26 family
H9Q80_RS02440	COG5001	Diguanylate cyclase
H9Q80_RS02455	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H9Q80_RS02460	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H9Q80_RS02465	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H9Q80_RS02475	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H9Q80_RS02485	COG0356	it plays a direct role in the translocation of protons across the membrane
H9Q80_RS02515	COG1131	(ABC) transporter
H9Q80_RS02605	COG1131	(ABC) transporter
H9Q80_RS02620	COG3279	Response regulator of the LytR AlgR family
H9Q80_RS02630	COG1131	(ABC) transporter
H9Q80_RS02665	COG0745	RESPONSE REGULATOR receiver
H9Q80_RS02670	COG1136	(ABC) transporter
H9Q80_RS02675	COG0577	efflux transmembrane transporter activity
H9Q80_RS02675	COG1136	(ABC) transporter
H9Q80_RS02705	COG1609	Transcriptional regulator
H9Q80_RS02720	COG5492	domain, Protein
H9Q80_RS02725	COG3716	PTS system mannose fructose sorbose family IID component
H9Q80_RS02730	COG3715	PTS system
H9Q80_RS02735	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS02740	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H9Q80_RS02745	COG0800	Aldolase
H9Q80_RS02755	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q80_RS02785	COG0018	arginyl-trna synthetase
H9Q80_RS02795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9Q80_RS02815	COG0784	Response regulator, receiver
H9Q80_RS02815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9Q80_RS02815	COG2205	protein histidine kinase activity
H9Q80_RS02815	COG2198	Histidine kinase
H9Q80_RS02820	COG5001	Diguanylate cyclase
H9Q80_RS02825	COG3870	Protein conserved in bacteria
H9Q80_RS02850	COG1473	amidohydrolase
H9Q80_RS02870	COG0012	GTP binding
H9Q80_RS02900	COG1476	TRANSCRIPTIONal
H9Q80_RS02910	COG4481	Protein conserved in bacteria
H9Q80_RS02915	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H9Q80_RS02920	COG1490	D-aminoacyl-tRNA deacylase activity
H9Q80_RS02930	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS02935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS02935	COG1263	PTS System
H9Q80_RS02935	COG2190	(PTS) system
H9Q80_RS02940	COG0024	Methionine aminopeptidase
H9Q80_RS02945	COG0733	neurotransmitter:sodium symporter activity
H9Q80_RS02950	COG3385	transposase activity
H9Q80_RS02955	COG3300	MHYT domain
H9Q80_RS02955	COG5001	Diguanylate cyclase
H9Q80_RS02975	COG1136	(ABC) transporter
H9Q80_RS02985	COG1475	DNA binding
H9Q80_RS02990	COG1192	Involved in chromosome partitioning
H9Q80_RS02995	COG1475	DNA binding
H9Q80_RS03035	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS03040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS03040	COG2190	(PTS) system
H9Q80_RS03040	COG1263	PTS System
H9Q80_RS03045	COG1737	Transcriptional regulator
H9Q80_RS03105	COG1476	TRANSCRIPTIONal
H9Q80_RS03115	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H9Q80_RS03125	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
H9Q80_RS03130	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H9Q80_RS03135	COG0287	Prephenate dehydrogenase
H9Q80_RS03195	COG4608	Belongs to the ABC transporter superfamily
H9Q80_RS03200	COG0444	Belongs to the ABC transporter superfamily
H9Q80_RS03205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9Q80_RS03210	COG0601	transmembrane transport
H9Q80_RS03220	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
H9Q80_RS03230	COG1737	Transcriptional regulator
H9Q80_RS03240	COG1309	transcriptional regulator
H9Q80_RS03420	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H9Q80_RS03425	COG3959	Transketolase, thiamine diphosphate binding domain
H9Q80_RS03430	COG0800	Aldolase
H9Q80_RS03440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9Q80_RS03445	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H9Q80_RS03445	COG0517	IMP dehydrogenase activity
H9Q80_RS03465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q80_RS03470	COG3711	transcriptional antiterminator
H9Q80_RS03470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q80_RS03520	COG3275	phosphorelay sensor kinase activity
H9Q80_RS03525	COG0745	RESPONSE REGULATOR receiver
H9Q80_RS03535	COG1136	(ABC) transporter
H9Q80_RS03545	COG1396	sequence-specific DNA binding
H9Q80_RS03555	COG3843	relaxase mobilization nuclease domain protein
H9Q80_RS03580	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS03585	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H9Q80_RS03595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H9Q80_RS03600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9Q80_RS03605	COG0434	BtpA family
H9Q80_RS03610	COG0434	BtpA family
H9Q80_RS03615	COG3716	PTS system mannose fructose sorbose family IID component
H9Q80_RS03625	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS03655	COG1876	peptidase activity
H9Q80_RS03660	COG0203	ribosomal protein L17
H9Q80_RS03665	COG0202	RNA polymerase activity
H9Q80_RS03670	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H9Q80_RS03675	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H9Q80_RS03690	COG0024	Methionine aminopeptidase
H9Q80_RS03695	COG0563	adenylate kinase activity
H9Q80_RS03700	COG0201	protein transport
H9Q80_RS03705	COG0200	Binds to the 23S rRNA
H9Q80_RS03710	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H9Q80_RS03715	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H9Q80_RS03730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9Q80_RS03730	COG0551	DNA topoisomerase type I activity
H9Q80_RS03830	COG3328	transposase activity
H9Q80_RS03880	COG3843	relaxase mobilization nuclease domain protein
H9Q80_RS03920	COG3177	Filamentation induced by cAMP protein fic
H9Q80_RS04000	COG0358	DNA primase activity
H9Q80_RS04050	COG2003	Belongs to the UPF0758 family
H9Q80_RS04170	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H9Q80_RS04175	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H9Q80_RS04180	COG3716	PTS system mannose fructose sorbose family IID component
H9Q80_RS04185	COG3715	PTS system
H9Q80_RS04285	COG0582	viral genome integration into host DNA
H9Q80_RS04315	COG1131	(ABC) transporter
H9Q80_RS04380	COG2197	response regulator
H9Q80_RS04395	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H9Q80_RS04405	COG1971	Probably functions as a manganese efflux pump
H9Q80_RS04420	COG0714	Associated with various cellular activities
H9Q80_RS04425	COG2425	protein containing a von Willebrand factor type A (vWA) domain
H9Q80_RS04430	COG3552	Protein containing von Willebrand factor type A (VWA) domain
H9Q80_RS04435	COG1131	(ABC) transporter
H9Q80_RS04445	COG3385	transposase activity
H9Q80_RS04460	COG1131	(ABC) transporter
H9Q80_RS04520	COG1725	Transcriptional regulator
H9Q80_RS04525	COG4106	trans-aconitate 2-methyltransferase activity
H9Q80_RS04540	COG0494	nUDIX hydrolase
H9Q80_RS04545	COG1373	ATPase (AAA superfamily
H9Q80_RS04555	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q80_RS04555	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS04575	COG3715	PTS system
H9Q80_RS04580	COG2188	Transcriptional regulator
H9Q80_RS04600	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS04605	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS04610	COG4978	Transcriptional regulator
H9Q80_RS04610	COG0789	Transcriptional regulator
H9Q80_RS04625	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS04630	COG3711	transcriptional antiterminator
H9Q80_RS04645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS04650	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS04665	COG1695	Transcriptional regulator
H9Q80_RS04700	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H9Q80_RS04705	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H9Q80_RS04715	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H9Q80_RS04720	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H9Q80_RS04745	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS04750	COG1263	PTS System
H9Q80_RS04750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS04750	COG2190	(PTS) system
H9Q80_RS04755	COG3711	transcriptional antiterminator
H9Q80_RS04765	COG0561	phosphatase activity
H9Q80_RS04800	COG1605	Chorismate mutase
H9Q80_RS04800	COG0077	Prephenate dehydratase
H9Q80_RS04805	COG2390	Transcriptional regulator
H9Q80_RS04810	COG3119	arylsulfatase activity
H9Q80_RS04825	COG0655	NAD(P)H dehydrogenase (quinone) activity
H9Q80_RS04845	COG1979	alcohol dehydrogenase
H9Q80_RS04855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9Q80_RS04855	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9Q80_RS04860	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9Q80_RS04865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q80_RS04865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9Q80_RS04865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9Q80_RS04870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q80_RS04870	COG3711	transcriptional antiterminator
H9Q80_RS04875	COG0129	dihydroxy-acid dehydratase activity
H9Q80_RS04885	COG1609	Transcriptional regulator
H9Q80_RS04895	COG0800	Aldolase
H9Q80_RS04900	COG1312	Catalyzes the dehydration of D-mannonate
H9Q80_RS04910	COG2226	methyltransferase
H9Q80_RS04920	COG1486	melibiose metabolic process
H9Q80_RS04925	COG1263	PTS System
H9Q80_RS04925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS04955	COG1263	PTS System
H9Q80_RS04955	COG2190	(PTS) system
H9Q80_RS04955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS04975	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
H9Q80_RS04990	COG3716	PTS system mannose fructose sorbose family IID component
H9Q80_RS04995	COG3715	PTS system
H9Q80_RS05015	COG3933	PFAM sigma-54 factor interaction domain-containing protein
H9Q80_RS05015	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H9Q80_RS05030	COG0561	phosphatase activity
H9Q80_RS05035	COG3958	Transketolase
H9Q80_RS05040	COG3959	Transketolase, thiamine diphosphate binding domain
H9Q80_RS05050	COG0235	Class ii aldolase
H9Q80_RS05065	COG3037	sugar-specific permease SgaT UlaA
H9Q80_RS05085	COG1349	DNA-binding transcription factor activity
H9Q80_RS05095	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q80_RS05100	COG3037	sugar-specific permease SgaT UlaA
H9Q80_RS05110	COG3119	arylsulfatase activity
H9Q80_RS05115	COG2390	Transcriptional regulator
H9Q80_RS05125	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS05135	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS05145	COG3711	transcriptional antiterminator
H9Q80_RS05170	COG3037	sugar-specific permease SgaT UlaA
H9Q80_RS05175	COG1349	DNA-binding transcription factor activity
H9Q80_RS05185	COG1349	DNA-binding transcription factor activity
H9Q80_RS05200	COG1263	PTS System
H9Q80_RS05200	COG2190	(PTS) system
H9Q80_RS05200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS05205	COG3711	transcriptional antiterminator
H9Q80_RS05210	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q80_RS05220	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS05230	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS05235	COG1447	Phosphotransferase system cellobiose-specific component IIA
H9Q80_RS05245	COG3394	polysaccharide catabolic process
H9Q80_RS05250	COG1263	PTS System
H9Q80_RS05250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS05250	COG2190	(PTS) system
H9Q80_RS05285	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS05290	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS05295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS05295	COG1263	PTS System
H9Q80_RS05305	COG3711	transcriptional antiterminator
H9Q80_RS05325	COG0534	Mate efflux family protein
H9Q80_RS05335	COG1854	S-ribosylhomocysteine lyase activity
H9Q80_RS05365	COG5263	repeat protein
H9Q80_RS05365	COG4193	domain, Protein
H9Q80_RS05380	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H9Q80_RS05395	COG1475	DNA binding
H9Q80_RS05515	COG1388	LysM domain
H9Q80_RS05515	COG0791	NLP P60 protein
H9Q80_RS05580	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H9Q80_RS05590	COG1592	Rubrerythrin
H9Q80_RS05610	COG0006	proline dipeptidase activity
H9Q80_RS05625	COG3104	oligopeptide transport
H9Q80_RS05640	COG1136	(ABC) transporter
H9Q80_RS05665	COG0602	queuosine metabolic process
H9Q80_RS05670	COG1328	CTP reductase activity
H9Q80_RS05675	COG0561	phosphatase activity
H9Q80_RS05680	COG1686	Belongs to the peptidase S11 family
H9Q80_RS05705	COG5002	protein histidine kinase activity
H9Q80_RS05710	COG0745	RESPONSE REGULATOR receiver
H9Q80_RS05720	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H9Q80_RS05725	COG1774	PSP1 C-terminal conserved region
H9Q80_RS05730	COG0470	DNA polymerase III
H9Q80_RS05735	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H9Q80_RS05750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS05785	COG1486	melibiose metabolic process
H9Q80_RS05815	COG1733	regulation of RNA biosynthetic process
H9Q80_RS05820	COG1881	PFAM PEBP family protein
H9Q80_RS05855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS05855	COG1263	PTS System
H9Q80_RS05865	COG1486	melibiose metabolic process
H9Q80_RS05870	COG2190	(PTS) system
H9Q80_RS05880	COG2201	protein-glutamate methylesterase activity
H9Q80_RS05890	COG1737	Transcriptional regulator
H9Q80_RS05910	COG3711	transcriptional antiterminator
H9Q80_RS05910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q80_RS05915	COG1373	ATPase (AAA superfamily
H9Q80_RS05920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS05965	COG4152	abc transporter atp-binding protein
H9Q80_RS05975	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS05985	COG1940	carbohydrate kinase activity
H9Q80_RS05990	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS05995	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS06010	COG0701	Predicted permease
H9Q80_RS06025	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H9Q80_RS06030	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H9Q80_RS06035	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H9Q80_RS06045	COG0772	Belongs to the SEDS family
H9Q80_RS06050	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H9Q80_RS06055	COG4116	CYTH
H9Q80_RS06070	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H9Q80_RS06075	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H9Q80_RS06080	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H9Q80_RS06085	COG0590	tRNA wobble adenosine to inosine editing
H9Q80_RS06095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H9Q80_RS06100	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H9Q80_RS06105	COG0187	DNA topoisomerase II activity
H9Q80_RS06110	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H9Q80_RS06170	COG3620	sequence-specific DNA binding
H9Q80_RS06175	COG0745	RESPONSE REGULATOR receiver
H9Q80_RS06180	COG1136	(ABC) transporter
H9Q80_RS06195	COG5002	protein histidine kinase activity
H9Q80_RS06200	COG0745	RESPONSE REGULATOR receiver
H9Q80_RS06205	COG0745	RESPONSE REGULATOR receiver
H9Q80_RS06235	COG0741	lytic transglycosylase activity
H9Q80_RS06235	COG0791	NLP P60 protein
H9Q80_RS06285	COG2946	Replication initiation factor
H9Q80_RS06290	COG1674	ftsk spoiiie
H9Q80_RS06295	COG3620	sequence-specific DNA binding
H9Q80_RS06320	COG0592	DNA-directed DNA polymerase activity
H9Q80_RS06325	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H9Q80_RS06350	COG1847	R3H domain protein
H9Q80_RS06355	COG3706	GGDEF domain
H9Q80_RS06360	COG0745	RESPONSE REGULATOR receiver
H9Q80_RS06375	COG5002	protein histidine kinase activity
H9Q80_RS06400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS06400	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS06405	COG1447	Phosphotransferase system cellobiose-specific component IIA
H9Q80_RS06410	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS06455	COG0193	aminoacyl-tRNA hydrolase activity
H9Q80_RS06460	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H9Q80_RS06470	COG1136	(ABC) transporter
H9Q80_RS06480	COG3620	sequence-specific DNA binding
H9Q80_RS06600	COG0791	NLP P60 protein
H9Q80_RS06600	COG0741	lytic transglycosylase activity
H9Q80_RS06650	COG2946	Replication initiation factor
H9Q80_RS06655	COG1674	ftsk spoiiie
H9Q80_RS06720	COG2002	toxin-antitoxin pair type II binding
H9Q80_RS06725	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H9Q80_RS06820	COG1917	Cupin 2, conserved barrel domain protein
H9Q80_RS06820	COG2207	Transcriptional regulator
H9Q80_RS06825	COG0697	spore germination
H9Q80_RS06845	COG1395	domain, Protein
H9Q80_RS06855	COG3620	sequence-specific DNA binding
H9Q80_RS06890	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS06895	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS06900	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS06950	COG1511	domain protein
H9Q80_RS06955	COG1136	(ABC) transporter
H9Q80_RS06955	COG0577	efflux transmembrane transporter activity
H9Q80_RS06975	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H9Q80_RS06980	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H9Q80_RS06980	COG3933	PFAM sigma-54 factor interaction domain-containing protein
H9Q80_RS06995	COG3715	PTS system
H9Q80_RS07000	COG3716	PTS system mannose fructose sorbose family IID component
H9Q80_RS07015	COG2222	sugar isomerase
H9Q80_RS07025	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H9Q80_RS07045	COG2199	diguanylate cyclase activity
H9Q80_RS07045	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
H9Q80_RS07050	COG0745	RESPONSE REGULATOR receiver
H9Q80_RS07075	COG1136	(ABC) transporter
H9Q80_RS07110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9Q80_RS07135	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H9Q80_RS07140	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H9Q80_RS07145	COG0745	RESPONSE REGULATOR receiver
H9Q80_RS07150	COG5002	protein histidine kinase activity
H9Q80_RS07150	COG0642	Histidine kinase
H9Q80_RS07155	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H9Q80_RS07160	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H9Q80_RS07195	COG0084	hydrolase, TatD family'
H9Q80_RS07205	COG1690	Belongs to the RtcB family
H9Q80_RS07230	COG1393	Belongs to the ArsC family
H9Q80_RS07235	COG2015	COG2015, Alkyl sulfatase and related hydrolases
H9Q80_RS07240	COG0456	acetyltransferase
H9Q80_RS07245	COG4608	Belongs to the ABC transporter superfamily
H9Q80_RS07250	COG0444	Belongs to the ABC transporter superfamily
H9Q80_RS07255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9Q80_RS07260	COG0601	transmembrane transport
H9Q80_RS07265	COG4166	transmembrane transport
H9Q80_RS07270	COG0673	inositol 2-dehydrogenase activity
H9Q80_RS07275	COG0494	nUDIX hydrolase
H9Q80_RS07280	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H9Q80_RS07285	COG1078	dGTPase activity
H9Q80_RS07290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9Q80_RS07315	COG3976	FMN-binding domain protein
H9Q80_RS07315	COG1053	succinate dehydrogenase
H9Q80_RS07325	COG1733	regulation of RNA biosynthetic process
H9Q80_RS07330	COG0785	Cytochrome C biogenesis protein
H9Q80_RS07335	COG3118	belongs to the thioredoxin family
H9Q80_RS07340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9Q80_RS07365	COG3620	sequence-specific DNA binding
H9Q80_RS07375	COG0561	phosphatase activity
H9Q80_RS07380	COG0514	ATP-dependent DNA helicase (RecQ)
H9Q80_RS07405	COG1737	Transcriptional regulator
H9Q80_RS07410	COG2190	(PTS) system
H9Q80_RS07410	COG1263	PTS System
H9Q80_RS07410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS07435	COG1136	(ABC) transporter
H9Q80_RS07460	COG5002	protein histidine kinase activity
H9Q80_RS07500	COG1309	transcriptional regulator
H9Q80_RS07510	COG0791	NLP P60 protein
H9Q80_RS07510	COG0741	lytic transglycosylase activity
H9Q80_RS07545	COG0596	Alpha beta hydrolase
H9Q80_RS07560	COG2946	Replication initiation factor
H9Q80_RS07570	COG1674	ftsk spoiiie
H9Q80_RS07595	COG1486	melibiose metabolic process
H9Q80_RS07600	COG1263	PTS System
H9Q80_RS07600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS07605	COG2188	Transcriptional regulator
H9Q80_RS07615	COG1263	PTS System
H9Q80_RS07615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS07620	COG0366	Alpha amylase catalytic
H9Q80_RS07640	COG3546	catalase activity
H9Q80_RS07675	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H9Q80_RS07680	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H9Q80_RS07710	COG0151	Belongs to the GarS family
H9Q80_RS07720	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q80_RS07745	COG1263	PTS System
H9Q80_RS07745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS07745	COG2190	(PTS) system
H9Q80_RS07755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q80_RS07765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9Q80_RS07770	COG0235	Class ii aldolase
H9Q80_RS07775	COG2213	PTS system mannitol-specific
H9Q80_RS07775	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q80_RS07785	COG3775	system Galactitol-specific IIC component
H9Q80_RS07800	COG0647	UMP catabolic process
H9Q80_RS07805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9Q80_RS07820	COG3959	Transketolase, thiamine diphosphate binding domain
H9Q80_RS07825	COG3958	Transketolase
H9Q80_RS07845	COG2190	(PTS) system
H9Q80_RS07845	COG1263	PTS System
H9Q80_RS07845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS07860	COG3711	transcriptional antiterminator
H9Q80_RS07895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H9Q80_RS07910	COG1263	PTS System
H9Q80_RS07910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS07925	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS07930	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS07950	COG0583	DNA-binding transcription factor activity
H9Q80_RS07955	COG0655	NAD(P)H dehydrogenase (quinone) activity
H9Q80_RS07960	COG2827	Endonuclease containing a URI domain
H9Q80_RS07985	COG1131	(ABC) transporter
H9Q80_RS08000	COG4716	Myosin-crossreactive antigen
H9Q80_RS08020	COG1609	Transcriptional regulator
H9Q80_RS08025	COG1263	PTS System
H9Q80_RS08025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS08030	COG1621	beta-fructofuranosidase activity
H9Q80_RS08035	COG3711	transcriptional antiterminator
H9Q80_RS08040	COG2190	(PTS) system
H9Q80_RS08040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS08040	COG1263	PTS System
H9Q80_RS08045	COG0363	glucosamine-6-phosphate deaminase activity
H9Q80_RS08080	COG2188	Transcriptional regulator
H9Q80_RS08100	COG3716	PTS system mannose fructose sorbose family IID component
H9Q80_RS08160	COG3708	Transcriptional regulator
H9Q80_RS08160	COG2207	Transcriptional regulator
H9Q80_RS08165	COG0778	Nitroreductase
H9Q80_RS08170	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS08195	COG0009	L-threonylcarbamoyladenylate synthase
H9Q80_RS08205	COG0698	ribose 5-phosphate isomerase
H9Q80_RS08225	COG0534	Mate efflux family protein
H9Q80_RS08235	COG1263	PTS System
H9Q80_RS08235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS08235	COG2190	(PTS) system
H9Q80_RS08240	COG3711	transcriptional antiterminator
H9Q80_RS08265	COG0534	Mate efflux family protein
H9Q80_RS08280	COG0352	thiamine-phosphate diphosphorylase activity
H9Q80_RS08290	COG3620	sequence-specific DNA binding
H9Q80_RS08300	COG0513	Belongs to the DEAD box helicase family
H9Q80_RS08315	COG0789	Transcriptional regulator
H9Q80_RS08325	COG0436	Aminotransferase
H9Q80_RS08330	COG1522	sequence-specific DNA binding
H9Q80_RS08365	COG1739	Uncharacterized protein family UPF0029
H9Q80_RS08385	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H9Q80_RS08400	COG0019	diaminopimelate decarboxylase activity
H9Q80_RS08440	COG0531	amino acid
H9Q80_RS08445	COG1362	aminopeptidase activity
H9Q80_RS08485	COG0285	dihydrofolate synthase activity
H9Q80_RS08490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9Q80_RS08500	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
H9Q80_RS08510	COG3588	fructose-bisphosphate aldolase
H9Q80_RS08525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H9Q80_RS08530	COG1213	nucleotidyl transferase
H9Q80_RS08540	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
H9Q80_RS08545	COG0081	regulation of translation
H9Q80_RS08550	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H9Q80_RS08560	COG2813	Specifically methylates the guanine in position
H9Q80_RS08565	COG0085	RNA polymerase activity
H9Q80_RS08570	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H9Q80_RS08595	COG1114	Component of the transport system for branched-chain amino acids
H9Q80_RS08600	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H9Q80_RS08605	COG0049	tRNA binding
H9Q80_RS08615	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H9Q80_RS08625	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H9Q80_RS08630	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H9Q80_RS08635	COG0051	transcription antitermination factor activity, RNA binding
H9Q80_RS08640	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H9Q80_RS08645	COG0088	Forms part of the polypeptide exit tunnel
H9Q80_RS08655	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H9Q80_RS08670	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H9Q80_RS08675	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H9Q80_RS08690	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
H9Q80_RS08695	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H9Q80_RS08700	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H9Q80_RS08705	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H9Q80_RS08720	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H9Q80_RS08730	COG0200	Binds to the 23S rRNA
H9Q80_RS08740	COG0563	adenylate kinase activity
H9Q80_RS08745	COG0024	Methionine aminopeptidase
H9Q80_RS08760	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H9Q80_RS08765	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H9Q80_RS08770	COG0202	RNA polymerase activity
H9Q80_RS08775	COG0203	ribosomal protein L17
H9Q80_RS08790	COG1876	peptidase activity
H9Q80_RS08795	COG2843	Capsule synthesis protein
H9Q80_RS08800	COG4122	O-methyltransferase activity
H9Q80_RS08815	COG1131	(ABC) transporter
H9Q80_RS08835	COG1122	ATPase activity
H9Q80_RS08840	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H9Q80_RS08845	COG0101	tRNA pseudouridine synthase activity
H9Q80_RS08855	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H9Q80_RS08955	COG0343	queuine tRNA-ribosyltransferase activity
H9Q80_RS09015	COG0583	DNA-binding transcription factor activity
H9Q80_RS09020	COG2706	6-phosphogluconolactonase activity
H9Q80_RS09025	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H9Q80_RS09030	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H9Q80_RS09060	COG1363	Peptidase, m42
H9Q80_RS09065	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9Q80_RS09065	COG2247	cell wall binding repeat
H9Q80_RS09075	COG1131	(ABC) transporter
H9Q80_RS09115	COG3290	protein histidine kinase activity
H9Q80_RS09120	COG3279	Response regulator of the LytR AlgR family
H9Q80_RS09125	COG1131	(ABC) transporter
H9Q80_RS09190	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS09195	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS09205	COG1363	Peptidase, m42
H9Q80_RS09210	COG1363	Peptidase, m42
H9Q80_RS09270	COG1164	Oligoendopeptidase f
H9Q80_RS09275	COG1447	Phosphotransferase system cellobiose-specific component IIA
H9Q80_RS09280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS09305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q80_RS09305	COG3711	transcriptional antiterminator
H9Q80_RS09315	COG1447	Phosphotransferase system cellobiose-specific component IIA
H9Q80_RS09320	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS09325	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS09335	COG1373	ATPase (AAA superfamily
H9Q80_RS09340	COG3177	Filamentation induced by cAMP protein fic
H9Q80_RS09360	COG1131	(ABC) transporter
H9Q80_RS09405	COG3385	transposase activity
H9Q80_RS09420	COG1363	Peptidase, m42
H9Q80_RS09425	COG1447	Phosphotransferase system cellobiose-specific component IIA
H9Q80_RS09430	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS09440	COG0006	proline dipeptidase activity
H9Q80_RS09445	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H9Q80_RS09460	COG1446	asparaginase
H9Q80_RS09465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9Q80_RS09470	COG3142	Participates in the control of copper homeostasis
H9Q80_RS09490	COG0366	Alpha amylase catalytic
H9Q80_RS09505	COG1940	carbohydrate kinase activity
H9Q80_RS09525	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS09540	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS09560	COG0366	Alpha amylase catalytic
H9Q80_RS09565	COG0714	Associated with various cellular activities
H9Q80_RS09585	COG1396	sequence-specific DNA binding
H9Q80_RS09600	COG3385	transposase activity
H9Q80_RS09610	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
H9Q80_RS09615	COG3878	Protein conserved in bacteria
H9Q80_RS09620	COG1253	flavin adenine dinucleotide binding
H9Q80_RS09625	COG1476	TRANSCRIPTIONal
H9Q80_RS09645	COG0640	Transcriptional regulator
H9Q80_RS09680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9Q80_RS09685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9Q80_RS09690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9Q80_RS09695	COG1120	ATPase activity
H9Q80_RS09700	COG0745	RESPONSE REGULATOR receiver
H9Q80_RS09705	COG2205	protein histidine kinase activity
H9Q80_RS09710	COG1136	(ABC) transporter
H9Q80_RS09730	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H9Q80_RS09750	COG1136	(ABC) transporter
H9Q80_RS09760	COG0726	polysaccharide deacetylase
H9Q80_RS09765	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H9Q80_RS09770	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H9Q80_RS09795	COG1192	Involved in chromosome partitioning
H9Q80_RS09935	COG0741	lytic transglycosylase activity
H9Q80_RS09945	COG1959	2 iron, 2 sulfur cluster binding
H9Q80_RS10065	COG0791	NLP P60 protein
H9Q80_RS10065	COG0741	lytic transglycosylase activity
H9Q80_RS10080	COG0551	DNA topoisomerase type I activity
H9Q80_RS10080	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9Q80_RS10100	COG3843	relaxase mobilization nuclease domain protein
H9Q80_RS10120	COG1129	ABC transporter
H9Q80_RS10130	COG1132	(ABC) transporter
H9Q80_RS10130	COG2375	cellular response to nickel ion
H9Q80_RS10135	COG1132	(ABC) transporter
H9Q80_RS10175	COG2203	Gaf domain
H9Q80_RS10175	COG2199	diguanylate cyclase activity
H9Q80_RS10185	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H9Q80_RS10195	COG4946	Tricorn protease homolog
H9Q80_RS10195	COG1506	peptidase
H9Q80_RS10195	COG0823	Involved in the tonB-independent uptake of proteins
H9Q80_RS10210	COG2199	diguanylate cyclase activity
H9Q80_RS10230	COG1263	PTS System
H9Q80_RS10230	COG2190	(PTS) system
H9Q80_RS10230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS10245	COG1070	Carbohydrate kinase
H9Q80_RS10250	COG4806	L-rhamnose isomerase
H9Q80_RS10255	COG0235	Class ii aldolase
H9Q80_RS10260	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS10275	COG0588	phosphoglycerate mutase activity
H9Q80_RS10310	COG1959	2 iron, 2 sulfur cluster binding
H9Q80_RS10315	COG5002	protein histidine kinase activity
H9Q80_RS10315	COG3447	MASE1 domain protein
H9Q80_RS10315	COG5001	Diguanylate cyclase
H9Q80_RS10330	COG5001	Diguanylate cyclase
H9Q80_RS10330	COG4251	negative regulation of phosphorylation
H9Q80_RS10330	COG2203	Gaf domain
H9Q80_RS10330	COG3706	GGDEF domain
H9Q80_RS10335	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
H9Q80_RS10350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9Q80_RS10360	COG3069	C4-dicarboxylate transmembrane transporter activity
H9Q80_RS10365	COG3069	C4-dicarboxylate transmembrane transporter activity
H9Q80_RS10370	COG3959	Transketolase, thiamine diphosphate binding domain
H9Q80_RS10375	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H9Q80_RS10470	COG2203	Gaf domain
H9Q80_RS10470	COG2199	diguanylate cyclase activity
H9Q80_RS10480	COG1653	transport
H9Q80_RS10485	COG0784	Response regulator, receiver
H9Q80_RS10485	COG2205	protein histidine kinase activity
H9Q80_RS10485	COG5002	protein histidine kinase activity
H9Q80_RS10490	COG3437	response regulator, receiver
H9Q80_RS10500	COG1027	Aspartate ammonia-lyase
H9Q80_RS10510	COG3279	Response regulator of the LytR AlgR family
H9Q80_RS10540	COG1609	Transcriptional regulator
H9Q80_RS10550	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
H9Q80_RS10600	COG0393	Putative heavy-metal-binding
H9Q80_RS10605	COG1077	Cell shape determining protein MreB Mrl
H9Q80_RS10610	COG2078	PFAM AMMECR1 domain protein
H9Q80_RS10610	COG3885	ferrous iron binding
H9Q80_RS10655	COG0460	homoserine dehydrogenase
H9Q80_RS10660	COG0527	aspartate kinase activity
H9Q80_RS10665	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H9Q80_RS10715	COG2177	Part of the ABC transporter FtsEX involved in
H9Q80_RS10725	COG1194	a g-specific adenine glycosylase
H9Q80_RS10755	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H9Q80_RS10760	COG2337	Toxic component of a toxin-antitoxin (TA) module
H9Q80_RS10825	COG1309	transcriptional regulator
H9Q80_RS10840	COG0789	Transcriptional regulator
H9Q80_RS10860	COG0406	alpha-ribazole phosphatase activity
H9Q80_RS10870	COG1136	(ABC) transporter
H9Q80_RS10910	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H9Q80_RS10915	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
H9Q80_RS10925	COG5002	protein histidine kinase activity
H9Q80_RS10930	COG0745	RESPONSE REGULATOR receiver
H9Q80_RS10955	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS10960	COG1263	PTS System
H9Q80_RS10960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS10960	COG2190	(PTS) system
H9Q80_RS10965	COG1011	Hydrolase
H9Q80_RS10975	COG1597	lipid kinase activity
H9Q80_RS10980	COG2966	Psort location CytoplasmicMembrane, score
H9Q80_RS10990	COG0826	peptidase U32
H9Q80_RS11025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9Q80_RS11025	COG0723	plastoquinol--plastocyanin reductase activity
H9Q80_RS11045	COG2205	protein histidine kinase activity
H9Q80_RS11050	COG0488	(ABC) transporter
H9Q80_RS11055	COG1228	amidohydrolase
H9Q80_RS11065	COG1846	Transcriptional regulator
H9Q80_RS11085	COG3711	transcriptional antiterminator
H9Q80_RS11090	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q80_RS11090	COG2213	PTS system mannitol-specific
H9Q80_RS11095	COG1105	Belongs to the carbohydrate kinase PfkB family
H9Q80_RS11100	COG1063	alcohol dehydrogenase
H9Q80_RS11135	COG1362	aminopeptidase activity
H9Q80_RS11150	COG1609	Transcriptional regulator
H9Q80_RS11155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS11160	COG3959	Transketolase, thiamine diphosphate binding domain
H9Q80_RS11165	COG3958	Transketolase
H9Q80_RS11170	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H9Q80_RS11195	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS11200	COG1447	Phosphotransferase system cellobiose-specific component IIA
H9Q80_RS11210	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H9Q80_RS11220	COG1773	rubredoxin
H9Q80_RS11225	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9Q80_RS11235	COG0488	(ABC) transporter
H9Q80_RS11300	COG3842	ATPase activity
H9Q80_RS11310	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H9Q80_RS11315	COG1687	branched-chain amino acid
H9Q80_RS11330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H9Q80_RS11335	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9Q80_RS11345	COG1131	(ABC) transporter
H9Q80_RS11365	COG0561	phosphatase activity
H9Q80_RS11380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9Q80_RS11385	COG0745	RESPONSE REGULATOR receiver
H9Q80_RS11390	COG2205	protein histidine kinase activity
H9Q80_RS11390	COG2770	Histidine kinase
H9Q80_RS11395	COG1472	Belongs to the glycosyl hydrolase 3 family
H9Q80_RS11405	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H9Q80_RS11410	COG1181	Belongs to the D-alanine--D-alanine ligase family
H9Q80_RS11415	COG2207	Transcriptional regulator
H9Q80_RS11415	COG1917	Cupin 2, conserved barrel domain protein
H9Q80_RS11420	COG5426	von Willebrand factor, type A
H9Q80_RS11425	COG3119	arylsulfatase activity
H9Q80_RS11435	COG1175	transmembrane transport
H9Q80_RS11440	COG0395	ABC-type sugar transport system, permease component
H9Q80_RS11455	COG3842	ATPase activity
H9Q80_RS11460	COG0789	Transcriptional regulator
H9Q80_RS11460	COG4978	Transcriptional regulator
H9Q80_RS11465	COG1509	lysine 2,3-aminomutase activity
H9Q80_RS11480	COG1278	Cold shock
H9Q80_RS11495	COG4193	domain, Protein
H9Q80_RS11495	COG5263	repeat protein
H9Q80_RS11505	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9Q80_RS11525	COG2183	response to ionizing radiation
H9Q80_RS11535	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS11545	COG3959	Transketolase, thiamine diphosphate binding domain
H9Q80_RS11550	COG3958	Transketolase
H9Q80_RS11570	COG0124	histidyl-tRNA synthetase
H9Q80_RS11575	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H9Q80_RS11580	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H9Q80_RS11585	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H9Q80_RS11590	COG0131	Imidazoleglycerol-phosphate dehydratase
H9Q80_RS11600	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H9Q80_RS11605	COG0107	imidazoleglycerol-phosphate synthase activity
H9Q80_RS11610	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H9Q80_RS11615	COG0140	phosphoribosyl-ATP diphosphatase activity
H9Q80_RS11635	COG2199	diguanylate cyclase activity
H9Q80_RS11645	COG1115	amino acid carrier protein
H9Q80_RS11650	COG1929	Belongs to the glycerate kinase type-1 family
H9Q80_RS11655	COG0640	Transcriptional regulator
H9Q80_RS11660	COG2226	methyltransferase
H9Q80_RS11665	COG2217	Heavy metal translocating P-type atpase
H9Q80_RS11695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9Q80_RS11720	COG1191	sigma factor activity
H9Q80_RS11735	COG0358	DNA primase activity
H9Q80_RS11770	COG0110	maltose O-acetyltransferase activity
H9Q80_RS11800	COG0519	Catalyzes the synthesis of GMP from XMP
H9Q80_RS11865	COG3620	sequence-specific DNA binding
H9Q80_RS11875	COG1748	Saccharopine dehydrogenase
H9Q80_RS11885	COG0232	Belongs to the dGTPase family. Type 2 subfamily
H9Q80_RS11890	COG3870	Protein conserved in bacteria
H9Q80_RS11940	COG2217	Heavy metal translocating P-type atpase
H9Q80_RS11950	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H9Q80_RS11955	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H9Q80_RS11970	COG0628	permease
H9Q80_RS11975	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H9Q80_RS11985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9Q80_RS12000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H9Q80_RS12010	COG3191	aminopeptidase activity
H9Q80_RS12045	COG1592	Rubrerythrin
H9Q80_RS12045	COG1773	rubredoxin
H9Q80_RS12065	COG0789	Transcriptional regulator
H9Q80_RS12100	COG0443	Heat shock 70 kDa protein
H9Q80_RS12105	COG0488	(ABC) transporter
H9Q80_RS12125	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H9Q80_RS12135	COG2815	serine threonine protein kinase
H9Q80_RS12135	COG0515	serine threonine protein kinase
H9Q80_RS12140	COG1162	GTPase activity
H9Q80_RS12155	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H9Q80_RS12160	COG1597	lipid kinase activity
H9Q80_RS12165	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H9Q80_RS12170	COG5263	repeat protein
H9Q80_RS12170	COG4193	domain, Protein
H9Q80_RS12180	COG0849	cell division
H9Q80_RS12185	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H9Q80_RS12210	COG0535	radical SAM domain protein
H9Q80_RS12250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H9Q80_RS12255	COG0569	domain protein
H9Q80_RS12285	COG1328	CTP reductase activity
H9Q80_RS12285	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H9Q80_RS12335	COG1609	Transcriptional regulator
H9Q80_RS12340	COG2203	Gaf domain
H9Q80_RS12340	COG3706	GGDEF domain
H9Q80_RS12340	COG4251	negative regulation of phosphorylation
H9Q80_RS12340	COG5001	Diguanylate cyclase
H9Q80_RS12345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS12345	COG1263	PTS System
H9Q80_RS12350	COG1621	beta-fructofuranosidase activity
H9Q80_RS12355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9Q80_RS12365	COG0366	Alpha amylase catalytic
H9Q80_RS12385	COG1131	(ABC) transporter
H9Q80_RS12410	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H9Q80_RS12430	COG3842	ATPase activity
H9Q80_RS12495	COG4335	DNA alkylation repair
H9Q80_RS12500	COG1213	nucleotidyl transferase
H9Q80_RS12510	COG2608	mercury ion transmembrane transporter activity
H9Q80_RS12525	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H9Q80_RS12535	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9Q80_RS12535	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H9Q80_RS12555	COG0312	modulator of DNA gyrase
H9Q80_RS12570	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H9Q80_RS12590	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q80_RS12595	COG1725	Transcriptional regulator
H9Q80_RS12615	COG1131	(ABC) transporter
H9Q80_RS12645	COG4978	Transcriptional regulator
H9Q80_RS12645	COG0789	Transcriptional regulator
H9Q80_RS12655	COG1132	(ABC) transporter
H9Q80_RS12665	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q80_RS12670	COG1447	Phosphotransferase system cellobiose-specific component IIA
H9Q80_RS12695	COG2188	Transcriptional regulator
H9Q80_RS12705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9Q80_RS12715	COG0105	UTP biosynthetic process
H9Q80_RS12730	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H9Q80_RS12745	COG1410	methionine synthase
H9Q80_RS12745	COG0646	methionine synthase
H9Q80_RS12760	COG3711	transcriptional antiterminator
H9Q80_RS12765	COG2190	(PTS) system
H9Q80_RS12765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS12765	COG1263	PTS System
H9Q80_RS12770	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS12790	COG3711	transcriptional antiterminator
H9Q80_RS12795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS12795	COG1263	PTS System
H9Q80_RS12795	COG2190	(PTS) system
H9Q80_RS12800	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS12820	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H9Q80_RS12820	COG0116	Belongs to the methyltransferase superfamily
H9Q80_RS12825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H9Q80_RS12840	COG1132	(ABC) transporter
H9Q80_RS12845	COG1316	TRANSCRIPTIONal
H9Q80_RS12850	COG0210	DNA helicase
H9Q80_RS12855	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H9Q80_RS12865	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H9Q80_RS12870	COG0154	amidase activity
H9Q80_RS12875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H9Q80_RS12940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS12940	COG1263	PTS System
H9Q80_RS12940	COG2190	(PTS) system
H9Q80_RS12945	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS12990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS12990	COG2190	(PTS) system
H9Q80_RS12990	COG1263	PTS System
H9Q80_RS12995	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS13000	COG3711	transcriptional antiterminator
H9Q80_RS13005	COG2814	Major facilitator Superfamily
H9Q80_RS13010	COG0205	6-phosphofructokinase activity
H9Q80_RS13025	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H9Q80_RS13050	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H9Q80_RS13060	COG0157	Belongs to the NadC ModD family
H9Q80_RS13065	COG1827	regulation of RNA biosynthetic process
H9Q80_RS13095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9Q80_RS13105	COG0439	Biotin carboxylase
H9Q80_RS13115	COG0825	malonyl-CoA metabolic process
H9Q80_RS13120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9Q80_RS13125	COG2070	2-Nitropropane dioxygenase
H9Q80_RS13135	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H9Q80_RS13140	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q80_RS13145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H9Q80_RS13150	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H9Q80_RS13160	COG0736	holo-[acyl-carrier-protein] synthase activity
H9Q80_RS13190	COG1301	dicarboxylic acid transport
H9Q80_RS13195	COG4989	oxidoreductase activity
H9Q80_RS13205	COG0210	DNA helicase
H9Q80_RS13235	COG0252	asparaginase activity
H9Q80_RS13250	COG0745	RESPONSE REGULATOR receiver
H9Q80_RS13255	COG2205	protein histidine kinase activity
H9Q80_RS13260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H9Q80_RS13265	COG0569	domain protein
H9Q80_RS13270	COG0569	domain protein
H9Q80_RS13280	COG0281	malic enzyme
H9Q80_RS13285	COG0114	fumarate hydratase activity
H9Q80_RS13335	COG0058	SHG alpha-glucan phosphorylase activity
H9Q80_RS13340	COG1640	4-alpha-glucanotransferase
H9Q80_RS13345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9Q80_RS13390	COG0071	Belongs to the small heat shock protein (HSP20) family
H9Q80_RS13405	COG0582	viral genome integration into host DNA
H9Q80_RS13450	COG1131	(ABC) transporter
H9Q80_RS13480	COG0741	lytic transglycosylase activity
H9Q80_RS13480	COG0791	NLP P60 protein
H9Q80_RS13530	COG2946	Replication initiation factor
H9Q80_RS13535	COG1674	ftsk spoiiie
H9Q80_RS13540	COG1683	Conserved Protein
H9Q80_RS13560	COG2207	Transcriptional regulator
H9Q80_RS13560	COG1917	Cupin 2, conserved barrel domain protein
H9Q80_RS13625	COG0791	NLP P60 protein
H9Q80_RS13625	COG0741	lytic transglycosylase activity
H9Q80_RS13655	COG2946	Replication initiation factor
H9Q80_RS13665	COG1674	ftsk spoiiie
H9Q80_RS13690	COG1309	transcriptional regulator
H9Q80_RS13710	COG0488	(ABC) transporter
H9Q80_RS13735	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
H9Q80_RS13750	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9Q80_RS13755	COG2270	Major facilitator Superfamily
H9Q80_RS13770	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H9Q80_RS13775	COG0372	Belongs to the citrate synthase family
H9Q80_RS13780	COG0473	3-isopropylmalate dehydrogenase activity
H9Q80_RS13785	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H9Q80_RS13795	COG0326	Molecular chaperone. Has ATPase activity
H9Q80_RS13810	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9Q80_RS13825	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H9Q80_RS13835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9Q80_RS13855	COG0242	peptide deformylase activity
H9Q80_RS13865	COG5001	Diguanylate cyclase
H9Q80_RS13865	COG3300	MHYT domain
H9Q80_RS13880	COG1012	belongs to the aldehyde dehydrogenase family
H9Q80_RS13885	COG0726	polysaccharide deacetylase
H9Q80_RS13925	COG0475	glutathione-regulated potassium exporter activity
H9Q80_RS13940	COG1269	ATP hydrolysis coupled proton transport
H9Q80_RS13960	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
H9Q80_RS13970	COG1394	ATPase activity, coupled to movement of substances
H9Q80_RS14010	COG0583	DNA-binding transcription factor activity
H9Q80_RS14020	COG1132	(ABC) transporter
H9Q80_RS14030	COG0446	pyridine nucleotide-disulphide oxidoreductase
H9Q80_RS14040	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
H9Q80_RS14050	COG0628	permease
H9Q80_RS14085	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H9Q80_RS14105	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H9Q80_RS14135	COG2946	Replication initiation factor
H9Q80_RS14160	COG3475	LICD family
H9Q80_RS14180	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H9Q80_RS14190	COG1213	nucleotidyl transferase
H9Q80_RS14210	COG0443	Heat shock 70 kDa protein
H9Q80_RS14220	COG1136	(ABC) transporter
H9Q80_RS14220	COG0577	efflux transmembrane transporter activity
H9Q80_RS14250	COG1373	ATPase (AAA superfamily
H9Q80_RS14260	COG3706	GGDEF domain
H9Q80_RS14265	COG0564	pseudouridine synthase activity
H9Q80_RS14270	COG2033	superoxide reductase activity
H9Q80_RS14275	COG0778	Nitroreductase
H9Q80_RS14290	COG2084	Dehydrogenase
H9Q80_RS14300	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H9Q80_RS14320	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H9Q80_RS14330	COG0726	polysaccharide deacetylase
H9Q80_RS14350	COG1074	ATP-dependent DNA helicase activity
H9Q80_RS14360	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H9Q80_RS14365	COG0514	ATP-dependent DNA helicase (RecQ)
H9Q80_RS14410	COG1104	cysteine desulfurase activity
H9Q80_RS14430	COG1518	maintenance of DNA repeat elements
H9Q80_RS14465	COG0280	phosphate acetyltransferase
H9Q80_RS14470	COG2155	Conserved Protein
H9Q80_RS14475	COG2190	(PTS) system
H9Q80_RS14480	COG2188	Transcriptional regulator
H9Q80_RS14485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS14485	COG1263	PTS System
H9Q80_RS14490	COG0366	Alpha amylase catalytic
H9Q80_RS14510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H9Q80_RS14515	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H9Q80_RS14520	COG0066	3-isopropylmalate dehydratase activity
H9Q80_RS14525	COG0473	3-isopropylmalate dehydrogenase activity
H9Q80_RS14530	COG1373	ATPase (AAA superfamily
H9Q80_RS14555	COG0598	Magnesium transport protein CorA
H9Q80_RS14560	COG1136	(ABC) transporter
H9Q80_RS14560	COG0577	efflux transmembrane transporter activity
H9Q80_RS14565	COG3279	Response regulator of the LytR AlgR family
H9Q80_RS14580	COG2884	Cell division ATP-binding protein ftsE
H9Q80_RS14585	COG2884	Cell division ATP-binding protein ftsE
H9Q80_RS14605	COG1380	Effector of murein hydrolase LrgA
H9Q80_RS14610	COG1346	cytolysis
H9Q80_RS14625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H9Q80_RS14650	COG0488	(ABC) transporter
H9Q80_RS14655	COG0519	Catalyzes the synthesis of GMP from XMP
H9Q80_RS14675	COG0544	peptidyl-prolyl cis-trans isomerase activity
H9Q80_RS14685	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H9Q80_RS14695	COG0640	Transcriptional regulator
H9Q80_RS14715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9Q80_RS14730	COG1966	Carbon starvation protein
H9Q80_RS14735	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H9Q80_RS14750	COG4656	Part of a membrane complex involved in electron transport
H9Q80_RS14755	COG4658	electron transport chain
H9Q80_RS14765	COG4660	Part of a membrane complex involved in electron transport
H9Q80_RS14770	COG4657	Part of a membrane complex involved in electron transport
H9Q80_RS14780	COG2878	Part of a membrane complex involved in electron transport
H9Q80_RS14800	COG1131	(ABC) transporter
H9Q80_RS14810	COG1131	(ABC) transporter
H9Q80_RS14830	COG1725	Transcriptional regulator
H9Q80_RS14860	COG3385	transposase activity
H9Q80_RS14870	COG1293	RNA-binding protein homologous to eukaryotic snRNP
H9Q80_RS14875	COG0194	GDP metabolic process
H9Q80_RS14880	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H9Q80_RS14905	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H9Q80_RS14940	COG3620	sequence-specific DNA binding
H9Q80_RS14960	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H9Q80_RS14965	COG2011	ABC-type metal ion transport system permease component
H9Q80_RS14970	COG1464	Belongs to the NlpA lipoprotein family
H9Q80_RS14975	COG1473	amidohydrolase
H9Q80_RS14985	COG0420	3'-5' exonuclease activity
H9Q80_RS14990	COG0419	ATPase involved in DNA repair
H9Q80_RS14995	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H9Q80_RS15060	COG2894	cell division
H9Q80_RS15075	COG1994	Peptidase M50
H9Q80_RS15090	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H9Q80_RS15105	COG1484	DNA-dependent DNA replication
H9Q80_RS15110	COG0205	6-phosphofructokinase activity
H9Q80_RS15125	COG1940	carbohydrate kinase activity
H9Q80_RS15130	COG2309	aminopeptidase activity
H9Q80_RS15135	COG1704	LemA family
H9Q80_RS15150	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H9Q80_RS15175	COG0459	protein refolding
H9Q80_RS15180	COG2199	diguanylate cyclase activity
H9Q80_RS15195	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H9Q80_RS15200	COG0561	phosphatase activity
H9Q80_RS15205	COG1609	Transcriptional regulator
H9Q80_RS15250	COG0540	Belongs to the ATCase OTCase family
H9Q80_RS15255	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H9Q80_RS15260	COG0505	Belongs to the CarA family
H9Q80_RS15265	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H9Q80_RS15270	COG0543	2 iron, 2 sulfur cluster binding
H9Q80_RS15275	COG0167	dihydroorotate dehydrogenase activity
H9Q80_RS15280	COG0284	orotidine-5'-phosphate decarboxylase activity
H9Q80_RS15285	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H9Q80_RS15310	COG2199	diguanylate cyclase activity
H9Q80_RS15365	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H9Q80_RS15370	COG0028	Belongs to the TPP enzyme family
H9Q80_RS15375	COG0440	acetolactate synthase activity
H9Q80_RS15380	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H9Q80_RS15385	COG0129	dihydroxy-acid dehydratase activity
H9Q80_RS15400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9Q80_RS15410	COG1285	pathogenesis
H9Q80_RS15420	COG0745	RESPONSE REGULATOR receiver
H9Q80_RS15435	COG1136	(ABC) transporter
H9Q80_RS15440	COG0577	efflux transmembrane transporter activity
H9Q80_RS15445	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H9Q80_RS15475	COG1132	(ABC) transporter
H9Q80_RS15480	COG1132	(ABC) transporter
H9Q80_RS15490	COG3711	transcriptional antiterminator
H9Q80_RS15495	COG1263	PTS System
H9Q80_RS15495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS15495	COG2190	(PTS) system
H9Q80_RS15510	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS15515	COG0756	dUTP diphosphatase activity
H9Q80_RS15520	COG2188	Transcriptional regulator
H9Q80_RS15560	COG1979	alcohol dehydrogenase
H9Q80_RS15565	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H9Q80_RS15570	COG0564	pseudouridine synthase activity
H9Q80_RS15585	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H9Q80_RS15595	COG1193	negative regulation of DNA recombination
H9Q80_RS15600	COG0322	excinuclease ABC activity
H9Q80_RS15605	COG2197	response regulator
H9Q80_RS15615	COG1876	peptidase activity
H9Q80_RS15620	COG5401	PFAM Sporulation and spore germination
H9Q80_RS15645	COG5001	Diguanylate cyclase
H9Q80_RS15645	COG1716	ATPase activity
H9Q80_RS15655	COG1191	sigma factor activity
H9Q80_RS15660	COG2190	(PTS) system
H9Q80_RS15660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS15660	COG1263	PTS System
H9Q80_RS15670	COG1263	PTS System
H9Q80_RS15670	COG2190	(PTS) system
H9Q80_RS15670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q80_RS15675	COG3711	transcriptional antiterminator
H9Q80_RS15680	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
H9Q80_RS15685	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H9Q80_RS15695	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H9Q80_RS15700	COG0799	negative regulation of ribosome biogenesis
H9Q80_RS15705	COG2226	methyltransferase
H9Q80_RS15710	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H9Q80_RS15725	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H9Q80_RS15735	COG3331	DNA recombination
H9Q80_RS15755	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H9Q80_RS15760	COG1058	Belongs to the CinA family
H9Q80_RS15760	COG1546	Belongs to the CinA family
H9Q80_RS15765	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H9Q80_RS15775	COG1692	metallophosphoesterase
H9Q80_RS15790	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H9Q80_RS15800	COG0612	Peptidase, M16
H9Q80_RS15805	COG0612	Peptidase, M16
H9Q80_RS15820	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
H9Q80_RS15825	COG1104	cysteine desulfurase activity
H9Q80_RS15850	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H9Q80_RS15870	COG0336	Belongs to the RNA methyltransferase TrmD family
H9Q80_RS15875	COG0335	large ribosomal subunit rRNA binding
H9Q80_RS15880	COG0681	Belongs to the peptidase S26 family
H9Q80_RS15885	COG0681	Belongs to the peptidase S26 family
H9Q80_RS15895	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H9Q80_RS15915	COG0758	DNA mediated transformation
H9Q80_RS15920	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9Q80_RS15925	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
H9Q80_RS15930	COG4974	Belongs to the 'phage' integrase family
H9Q80_RS15935	COG0052	Belongs to the universal ribosomal protein uS2 family
H9Q80_RS15940	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H9Q80_RS15945	COG0528	UMP kinase activity
H9Q80_RS15950	COG0233	cytoplasmic translational termination
H9Q80_RS15955	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H9Q80_RS15960	COG4589	Belongs to the CDS family
H9Q80_RS15965	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H9Q80_RS15970	COG0750	zinc metalloprotease
H9Q80_RS15980	COG0268	Binds directly to 16S ribosomal RNA
H9Q80_RS16000	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H9Q80_RS16005	COG0481	GTPase activity
H9Q80_RS16010	COG4565	transcriptional regulatory protein
H9Q80_RS16015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H9Q80_RS16025	COG0582	viral genome integration into host DNA
H9Q80_RS16085	COG3584	3D domain protein
H9Q80_RS16100	COG5377	YqaJ viral recombinase family
H9Q80_RS16115	COG3723	Recombinational DNA repair protein, rece pathway
H9Q80_RS16185	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H9Q80_RS16195	COG0629	single-stranded DNA binding
H9Q80_RS16400	COG0534	Mate efflux family protein
H9Q80_RS16420	COG0482	sulfurtransferase activity
H9Q80_RS16425	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H9Q80_RS16435	COG0628	permease
H9Q80_RS16440	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H9Q80_RS16445	COG4472	Bacterial protein of unknown function (DUF965)
H9Q80_RS16450	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H9Q80_RS16455	COG3906	Belongs to the UPF0473 family
H9Q80_RS16460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H9Q80_RS16465	COG0572	uridine kinase
H9Q80_RS16470	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9Q80_RS16475	COG1596	polysaccharide export
H9Q80_RS16475	COG1555	photosystem II stabilization
H9Q80_RS16480	COG2333	competence protein COMEC
H9Q80_RS16480	COG0658	competence protein
H9Q80_RS16485	COG1466	dna polymerase III delta subunit
H9Q80_RS16490	COG1760	l-serine dehydratase
H9Q80_RS16505	COG0552	protein localization to endoplasmic reticulum
H9Q80_RS16510	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
H9Q80_RS16515	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H9Q80_RS16520	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H9Q80_RS16530	COG0587	DNA-directed DNA polymerase activity
H9Q80_RS16540	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H9Q80_RS16545	COG2868	ribosomal protein
H9Q80_RS16550	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H9Q80_RS16555	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H9Q80_RS16570	COG0515	serine threonine protein kinase
H9Q80_RS16570	COG2815	serine threonine protein kinase
H9Q80_RS16575	COG0515	serine threonine protein kinase
H9Q80_RS16575	COG2815	serine threonine protein kinase
H9Q80_RS16585	COG0708	Exodeoxyribonuclease III
H9Q80_RS16605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9Q80_RS16610	COG1120	ATPase activity
H9Q80_RS16625	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H9Q80_RS16625	COG2080	2 iron, 2 sulfur cluster binding
H9Q80_RS16645	COG0534	Mate efflux family protein
H9Q80_RS16650	COG0632	four-way junction helicase activity
H9Q80_RS16655	COG2255	four-way junction helicase activity
H9Q80_RS16665	COG2323	membrane
H9Q80_RS16670	COG2244	polysaccharide biosynthetic process
H9Q80_RS16680	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9Q80_RS16680	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9Q80_RS16685	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H9Q80_RS16685	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H9Q80_RS16690	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H9Q80_RS16695	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H9Q80_RS16705	COG3620	sequence-specific DNA binding
H9Q80_RS16715	COG1323	Belongs to the UPF0348 family
H9Q80_RS16725	COG1399	metal-binding, possibly nucleic acid-binding protein
H9Q80_RS16730	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H9Q80_RS16745	COG0195	Participates in both transcription termination and antitermination
H9Q80_RS16750	COG2740	Nucleic-acid-binding protein implicated in transcription termination
H9Q80_RS16760	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H9Q80_RS16765	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H9Q80_RS16775	COG2197	response regulator
H9Q80_RS16780	COG4585	Histidine kinase
H9Q80_RS16785	COG1131	(ABC) transporter
H9Q80_RS16800	COG2723	6-phospho-beta-galactosidase activity
H9Q80_RS16820	COG4464	protein tyrosine phosphatase activity
H9Q80_RS16845	COG1088	dTDP-glucose 4,6-dehydratase activity
H9Q80_RS16850	COG1091	dTDP-4-dehydrorhamnose reductase activity
H9Q80_RS16855	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
H9Q80_RS16875	COG1215	transferase activity, transferring glycosyl groups
H9Q80_RS16890	COG0110	maltose O-acetyltransferase activity
H9Q80_RS16920	COG3385	transposase activity
H9Q80_RS16925	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H9Q80_RS16940	COG0488	(ABC) transporter
H9Q80_RS16955	COG0531	amino acid
H9Q80_RS16960	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H9Q80_RS16965	COG0187	DNA topoisomerase II activity
H9Q80_RS16970	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H9Q80_RS17005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9Q80_RS17015	COG0697	spore germination
H9Q80_RS17040	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H9Q80_RS17045	COG0745	RESPONSE REGULATOR receiver
H9Q80_RS17050	COG5002	protein histidine kinase activity
H9Q80_RS17070	COG1983	PspC domain protein
H9Q80_RS17075	COG0659	secondary active sulfate transmembrane transporter activity
H9Q80_RS17085	COG1686	Belongs to the peptidase S11 family
H9Q80_RS17090	COG2715	membrane protein required for spore maturation
H9Q80_RS17095	COG0700	Nucleoside recognition
H9Q80_RS17120	COG1131	(ABC) transporter
H9Q80_RS17130	COG1187	pseudouridine synthase activity
H9Q80_RS17135	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H9Q80_RS17145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9Q80_RS17150	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H9Q80_RS17165	COG1126	abc transporter atp-binding protein
H9Q80_RS17185	COG1702	phosphate starvation-inducible protein PhoH
H9Q80_RS17190	COG0745	RESPONSE REGULATOR receiver
H9Q80_RS17195	COG5002	protein histidine kinase activity
H9Q80_RS17205	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H9Q80_RS17215	COG0581	inorganic phosphate transmembrane transporter activity
H9Q80_RS17220	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H9Q80_RS17235	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H9Q80_RS17240	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H9Q80_RS17245	COG0295	cytidine deaminase activity
H9Q80_RS17250	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H9Q80_RS17255	COG1381	Involved in DNA repair and RecF pathway recombination
H9Q80_RS17265	COG0358	DNA primase activity
H9Q80_RS17265	COG0305	Participates in initiation and elongation during chromosome replication
H9Q80_RS17270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H9Q80_RS17280	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H9Q80_RS17285	COG0513	Belongs to the DEAD box helicase family
H9Q80_RS17310	COG0768	penicillin binding
H9Q80_RS17315	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H9Q80_RS17320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9Q80_RS17330	COG4537	Required for transformation and DNA binding
H9Q80_RS17360	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H9Q80_RS17370	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H9Q80_RS17375	COG1160	GTP binding
H9Q80_RS17380	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H9Q80_RS17385	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H9Q80_RS17395	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H9Q80_RS17400	COG0776	regulation of translation
H9Q80_RS17405	COG2738	Putative neutral zinc metallopeptidase
H9Q80_RS17425	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H9Q80_RS17430	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H9Q80_RS17435	COG0504	CTP synthase activity
H9Q80_RS17445	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H9Q80_RS17465	COG2264	protein methyltransferase activity
H9Q80_RS17485	COG0750	zinc metalloprotease
H9Q80_RS17490	COG0497	DNA recombination
H9Q80_RS17495	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
H9Q80_RS17500	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H9Q80_RS17505	COG0142	geranyltranstransferase activity
H9Q80_RS17510	COG1722	exodeoxyribonuclease VII activity
H9Q80_RS17520	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9Q80_RS17550	COG0196	riboflavin kinase activity
H9Q80_RS17555	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H9Q80_RS17570	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
H9Q80_RS17585	COG1136	(ABC) transporter
H9Q80_RS17590	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
H9Q80_RS17595	COG0124	histidyl-tRNA synthetase
H9Q80_RS17605	COG0217	transcriptional regulatory protein
H9Q80_RS17615	COG0495	leucyl-tRNA aminoacylation
H9Q80_RS17625	COG0493	'glutamate synthase
H9Q80_RS17625	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H9Q80_RS17640	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H9Q80_RS17645	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
H9Q80_RS17650	COG2205	protein histidine kinase activity
H9Q80_RS17655	COG1307	EDD domain protein, DegV family
H9Q80_RS17665	COG1242	4 iron, 4 sulfur cluster binding
H9Q80_RS17670	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H9Q80_RS17680	COG0647	UMP catabolic process
H9Q80_RS17720	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H9Q80_RS17725	COG1187	pseudouridine synthase activity
H9Q80_RS17730	COG2244	polysaccharide biosynthetic process
H9Q80_RS17750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9Q80_RS17765	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H9Q80_RS17770	COG1609	Transcriptional regulator
H9Q80_RS17785	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H9Q80_RS17795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9Q80_RS17800	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H9Q80_RS17805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9Q80_RS17815	COG1185	polyribonucleotide nucleotidyltransferase activity
H9Q80_RS17820	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H9Q80_RS17825	COG0733	neurotransmitter:sodium symporter activity
H9Q80_RS17830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9Q80_RS17835	COG3763	UPF0154 protein
H9Q80_RS17865	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H9Q80_RS17870	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H9Q80_RS17875	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H9Q80_RS17880	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H9Q80_RS17885	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H9Q80_RS17890	COG0165	Argininosuccinate lyase
H9Q80_RS17900	COG0137	argininosuccinate synthase activity
H9Q80_RS17920	COG0561	phosphatase activity
H9Q80_RS17930	COG0717	Belongs to the dCTP deaminase family
H9Q80_RS17940	COG1024	Enoyl-CoA hydratase
H9Q80_RS17945	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9Q80_RS17950	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H9Q80_RS17955	COG2086	electron transfer activity
H9Q80_RS17960	COG1960	acyl-CoA dehydrogenase activity
H9Q80_RS17965	COG0183	Belongs to the thiolase family
H9Q80_RS17985	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H9Q80_RS17995	COG2203	Gaf domain
H9Q80_RS17995	COG2199	diguanylate cyclase activity
H9Q80_RS18015	COG2873	o-acetylhomoserine
H9Q80_RS18085	COG1595	DNA-templated transcription, initiation
H9Q80_RS18120	COG3409	Peptidoglycan-binding domain 1 protein
H9Q80_RS18120	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9Q80_RS18135	COG1131	(ABC) transporter
H9Q80_RS18145	COG1396	sequence-specific DNA binding
H9Q80_RS18150	COG0561	phosphatase activity
H9Q80_RS18160	COG1131	(ABC) transporter
H9Q80_RS18175	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H9Q80_RS18180	COG0719	Fe-S assembly protein
H9Q80_RS18185	COG0822	iron-sulfur transferase activity
H9Q80_RS18190	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H9Q80_RS18195	COG0719	Fe-S assembly protein
H9Q80_RS18200	COG0396	ATPase activity
H9Q80_RS18215	COG0537	adenosine 5'-monophosphoramidase activity
H9Q80_RS18230	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H9Q80_RS18235	COG0742	ribosomal rna small subunit methyltransferase
H9Q80_RS18240	COG0772	Belongs to the SEDS family
H9Q80_RS18250	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H9Q80_RS18255	COG1408	metallophosphoesterase
H9Q80_RS18270	COG0072	phenylalanine-tRNA ligase activity
H9Q80_RS18270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9Q80_RS18275	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H9Q80_RS18320	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H9Q80_RS18360	COG1131	(ABC) transporter
H9Q80_RS18395	COG2814	Major facilitator Superfamily
H9Q80_RS18400	COG4977	sequence-specific DNA binding
H9Q80_RS18410	COG0741	lytic transglycosylase activity
H9Q80_RS18410	COG0791	NLP P60 protein
H9Q80_RS18460	COG2946	Replication initiation factor
H9Q80_RS18465	COG1674	ftsk spoiiie
H9Q80_RS18470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9Q80_RS18505	COG0456	acetyltransferase
H9Q80_RS18515	COG1131	(ABC) transporter
H9Q80_RS18535	COG1136	(ABC) transporter
H9Q80_RS18540	COG0768	penicillin binding
H9Q80_RS18555	COG1288	antiporter activity
H9Q80_RS18565	COG1136	(ABC) transporter
H9Q80_RS18570	COG5002	protein histidine kinase activity
H9Q80_RS18575	COG0745	RESPONSE REGULATOR receiver
H9Q80_RS18580	COG1131	(ABC) transporter
H9Q80_RS18590	COG0346	lactoylglutathione lyase activity
H9Q80_RS18615	COG1307	EDD domain protein, DegV family
H9Q80_RS18625	COG2378	regulation of single-species biofilm formation
H9Q80_RS18635	COG0456	acetyltransferase
H9Q80_RS18665	COG1272	protein, Hemolysin III
H9Q80_RS18670	COG1307	EDD domain protein, DegV family
H9Q80_RS18680	COG1132	(ABC) transporter
H9Q80_RS18685	COG1132	(ABC) transporter
H9Q80_RS18695	COG1690	Belongs to the RtcB family
H9Q80_RS18700	COG0745	RESPONSE REGULATOR receiver
H9Q80_RS18705	COG5002	protein histidine kinase activity
H9Q80_RS18745	COG2207	Transcriptional regulator
H9Q80_RS18745	COG4753	response regulator
H9Q80_RS18750	COG3275	phosphorelay sensor kinase activity
H9Q80_RS18765	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H9Q80_RS18765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9Q80_RS18780	COG3842	ATPase activity
H9Q80_RS18790	COG0523	cobalamin synthesis protein
H9Q80_RS18805	COG1131	(ABC) transporter
H9Q80_RS18820	COG1115	amino acid carrier protein
H9Q80_RS18845	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H9Q80_RS18855	COG4120	Belongs to the binding-protein-dependent transport system permease family
H9Q80_RS18865	COG0493	'glutamate synthase
H9Q80_RS18865	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H9Q80_RS18900	COG0519	Catalyzes the synthesis of GMP from XMP
H9Q80_RS18900	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H9Q80_RS18905	COG2252	PERMEase
H9Q80_RS18915	COG0436	Aminotransferase
H9Q80_RS18920	COG3706	GGDEF domain
H9Q80_RS19000	COG5002	protein histidine kinase activity
H9Q80_RS19000	COG0784	Response regulator, receiver
H9Q80_RS19000	COG2198	Histidine kinase
H9Q80_RS19185	COG0110	maltose O-acetyltransferase activity
H9Q80_RS19200	COG1918	ferrous iron import across plasma membrane
H9Q80_RS19200	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H9Q80_RS19225	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H9Q80_RS19230	COG0557	exoribonuclease II activity
H9Q80_RS19235	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H9Q80_RS19245	COG0643	Histidine kinase
H9Q80_RS19245	COG2198	Histidine kinase
H9Q80_RS19250	COG0745	RESPONSE REGULATOR receiver
H9Q80_RS19255	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
H9Q80_RS19260	COG1776	CheC inhibitor of MCP methylation
H9Q80_RS19265	COG2201	protein-glutamate methylesterase activity
H9Q80_RS19270	COG0840	transmembrane signaling receptor activity
H9Q80_RS19275	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
H9Q80_RS19285	COG2201	protein-glutamate methylesterase activity
H9Q80_RS19290	COG2201	protein-glutamate methylesterase activity
H9Q80_RS19325	COG0250	Participates in transcription elongation, termination and antitermination
H9Q80_RS19335	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H9Q80_RS19345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9Q80_RS19350	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
H9Q80_RS19355	COG0215	cysteine-tRNA ligase activity
H9Q80_RS19375	COG0740	serine-type endopeptidase activity
H9Q80_RS19380	COG5001	Diguanylate cyclase
H9Q80_RS19380	COG3300	MHYT domain