locus-tag	class	description
HOS65_gp01	COG0582	viral genome integration into host DNA
HOS65_gp03	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HOS65_gp14	COG1061	Type III restriction enzyme res subunit
HOS65_gp16	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HOS65_gp18	COG3728	DNA packaging
HOS65_gp18	COG5484	DNA packaging
HOS65_gp39	COG3757	hydrolase, family 25