locus-tag	class	description
HER31_RS00010	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HER31_RS00025	ENOG4105F0N	pyrophosphate phospho-hydrolase
HER31_RS00030	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HER31_RS00035	ENOG4105DFD	Na H antiporter
HER31_RS00040	ENOG4105DFU	Cell wall formation (By similarity)
HER31_RS00045	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HER31_RS00050	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HER31_RS00055	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HER31_RS00060	ENOG4105C34	Pseudouridine synthase
HER31_RS00065	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HER31_RS00070	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HER31_RS00100	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
HER31_RS00105	ENOG4105BZU	Histidine kinase
HER31_RS00110	ENOG41065U4	response regulator
HER31_RS00115	ENOG4105CFH	Aspartokinase
HER31_RS00120	ENOG4108VVK	transcriptional Regulator, AsnC
HER31_RS00125	ENOG4105CU9	asparagine synthetase A
HER31_RS00130	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
HER31_RS00135	ENOG4105D3G	Pseudouridine synthase
HER31_RS00165	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HER31_RS00170	ENOG4105F7P	transcriptional regulator AsnC family
HER31_RS00175	ENOG4105DVH	amino acid
HER31_RS00180	ENOG4105I08	Pseudouridine synthase
HER31_RS00195	ENOG4106CC8	Bacterial inner membrane protein
HER31_RS00200	ENOG41086KC	Transcriptional regulator
HER31_RS00205	ENOG41086KC	Transcriptional regulator
HER31_RS00230	ENOG4105E0U	tyrosine-specific transport protein
HER31_RS00235	ENOG4105CZH	peptidase
HER31_RS00245	ENOG4107ZT5	Thiol disulfide interchange protein
HER31_RS00250	ENOG4108DMF	Cytochrome C biogenesis protein
HER31_RS00255	ENOG4105DA4	cytochrome c-type biogenesis protein
HER31_RS00260	ENOG4105V2T	cytochrome C
HER31_RS00270	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HER31_RS00280	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HER31_RS00285	ENOG4105DVI	reductase, NrfD
HER31_RS00290	ENOG4105V2T	cytochrome C
HER31_RS00300	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HER31_RS00310	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HER31_RS00315	ENOG4105DVI	reductase, NrfD
HER31_RS00330	ENOG4105CIG	ABC transporter
HER31_RS00335	ENOG4108T0W	nitrous oxide maturation protein NosY
HER31_RS00345	ENOG4107SIQ	Naphthoate synthase
HER31_RS00350	ENOG4105M6F	mutator MutT protein
HER31_RS00360	ENOG4107QP8	phosphohexose isomerase
HER31_RS00365	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HER31_RS00375	ENOG4105D1Q	UPF0246 protein
HER31_RS00385	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HER31_RS00390	ENOG4105CJR	Integral membrane protein (MviN
HER31_RS00395	ENOG4105DTN	riboflavin biosynthesis protein ribF
HER31_RS00400	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HER31_RS00405	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HER31_RS00410	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
HER31_RS00415	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HER31_RS00445	ENOG4105CWU	Biogenesis protein
HER31_RS00450	ENOG4106855	Competence protein
HER31_RS00455	ENOG4105C4K	Nad synthetase
HER31_RS00460	ENOG4108YZA	Nitrogen regulatory protein pii
HER31_RS00465	ENOG4105DA5	(ABC) transporter
HER31_RS00470	ENOG4105E3A	(ABC) transporter
HER31_RS00475	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HER31_RS00520	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HER31_RS00525	ENOG4105BZU	Histidine kinase
HER31_RS00535	ENOG4105D7Z	glutathione synthase
HER31_RS00540	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HER31_RS00550	ENOG4105GPY	SprT protein
HER31_RS00560	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HER31_RS00570	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HER31_RS00585	ENOG4105KA0	thioesterase Superfamily protein
HER31_RS00595	ENOG4108JU6	CBS domain protein
HER31_RS00600	ENOG4106KVJ	cytochrome C assembly protein
HER31_RS00605	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HER31_RS00615	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HER31_RS00620	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HER31_RS00625	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HER31_RS00630	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HER31_RS00635	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
HER31_RS00675	ENOG4105PDP	Short chain dehydrogenase
HER31_RS00680	ENOG4105CQC	Prephenate dehydratase
HER31_RS00685	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
HER31_RS00700	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
HER31_RS00710	ENOG4105R2J	Conserved Protein
HER31_RS00715	ENOG4105BZU	Histidine kinase
HER31_RS00720	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HER31_RS00725	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HER31_RS00730	ENOG4105DXN	mazG family
HER31_RS00735	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HER31_RS00745	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HER31_RS00750	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HER31_RS00755	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HER31_RS00770	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HER31_RS00785	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HER31_RS00790	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HER31_RS00795	ENOG4105Y3E	Modulates RecA activity (By similarity)
HER31_RS00810	ENOG4105CIZ	coA-substrate-specific enzyme activase
HER31_RS00815	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
HER31_RS00820	ENOG4105C9B	Cysteine desulfurase
HER31_RS00825	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HER31_RS00830	ENOG4105CFH	Aspartokinase
HER31_RS00835	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
HER31_RS00875	ENOG4105KPV	Transcriptional regulator
HER31_RS00880	ENOG4105W39	Membrane
HER31_RS00890	ENOG4105D9M	gamma-glutamylcysteine synthetase
HER31_RS00895	ENOG410829K	Lysine exporter protein (Lyse ygga)
HER31_RS00905	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HER31_RS00910	ENOG4105CTB	Polyprenyl synthetase
HER31_RS00915	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HER31_RS00920	ENOG4105E14	MotA TolQ exbB proton channel
HER31_RS00925	ENOG4106VK6	Flagellar motor protein
HER31_RS00930	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
HER31_RS00940	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HER31_RS00945	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HER31_RS00955	ENOG4108VPT	UPF0234 protein
HER31_RS00965	ENOG4108MR7	Arylsulfotransferase
HER31_RS00970	ENOG4105EYM	Major Facilitator superfamily
HER31_RS00985	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HER31_RS00995	ENOG4105M85	Bola protein
HER31_RS01005	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HER31_RS01010	ENOG4105CH5	extracellular solute-binding protein, family 7
HER31_RS01020	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HER31_RS01025	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HER31_RS01035	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HER31_RS01040	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HER31_RS01045	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
HER31_RS01050	ENOG4105CJ2	(LipO)protein
HER31_RS01055	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HER31_RS01060	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HER31_RS01080	ENOG4105D3R	alkyl hydroperoxide reductase
HER31_RS01085	ENOG4108JU3	Alkyl hydroperoxide reductase
HER31_RS01095	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HER31_RS01100	ENOG4105BZS	acriflavin resistance protein
HER31_RS01105	ENOG4105ETX	regulatoR
HER31_RS01110	ENOG4107WP9	Histidine kinase
HER31_RS01120	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HER31_RS01150	ENOG4107QNJ	CoA-transferase subunit B
HER31_RS01155	ENOG4105D6N	CoA-transferase, subunit a
HER31_RS01170	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HER31_RS01180	ENOG4105E39	Enoyl-CoA hydratase
HER31_RS01185	ENOG4107QX3	carboxylase
HER31_RS01190	ENOG4105C1G	acyl-Coa dehydrogenase
HER31_RS01195	ENOG4108Z6Z	Transcriptional regulator
HER31_RS01200	ENOG4105YGK	Pfam:UPF0157
HER31_RS01205	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HER31_RS01210	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HER31_RS01215	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
HER31_RS01220	ENOG4105C29	acyl-CoA thioesterase
HER31_RS01225	ENOG4105BZG	amino acid carrier protein
HER31_RS01235	ENOG4107RGM	aldo keto reductase
HER31_RS01240	ENOG4105EIF	outer membrane protein W
HER31_RS01245	ENOG4108JQ1	Dehydrogenase
HER31_RS01250	ENOG4107Z3H	Transcriptional regulator, TetR family
HER31_RS01255	ENOG4107RGH	Aldehyde dehydrogenase
HER31_RS01265	ENOG4105E66	phosphoriboisomerase A
HER31_RS01270	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HER31_RS01275	ENOG4108ZNX	Heat shock protein
HER31_RS01290	ENOG4105C1J	atp-dependent rna helicase
HER31_RS01295	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
HER31_RS01300	ENOG4105BZU	Histidine kinase
HER31_RS01315	ENOG410903C	(LipO)protein
HER31_RS01320	ENOG4105I93	response regulator
HER31_RS01330	ENOG4108PTX	LysR family Transcriptional regulator
HER31_RS01350	ENOG4105EUZ	Beta-lactamase domain protein
HER31_RS01355	ENOG4105HEI	LysR family (Transcriptional regulator
HER31_RS01365	ENOG4105T0Z	Conserved Protein
HER31_RS01395	ENOG4105CKI	cobalamin synthesis protein
HER31_RS01405	ENOG4105K6V	RNA polymerase
HER31_RS01415	ENOG4105EMU	Dehydrogenase
HER31_RS01430	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HER31_RS01450	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HER31_RS01455	ENOG4108VWS	Yaeq family
HER31_RS01465	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HER31_RS01475	ENOG4105C1J	atp-dependent rna helicase
HER31_RS01490	ENOG410904A	RNA polymerase
HER31_RS01525	ENOG4105CUB	amino acid
HER31_RS01535	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
HER31_RS01540	ENOG4106D67	ethanolamine utilization protein
HER31_RS01550	ENOG4105CPD	ethanolamine ammonia-lyase
HER31_RS01555	ENOG4105DYY	Reactivating factor for ethanolamine ammonia lyase
HER31_RS01560	ENOG4105C0A	alcohol dehydrogenase
HER31_RS01565	ENOG4107YMV	ethanolamine utilization protein
HER31_RS01570	ENOG4108EKI	Dehydrogenase
HER31_RS01575	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
HER31_RS01580	ENOG4105KNY	Microcompartments protein
HER31_RS01585	ENOG4105KNY	Microcompartments protein
HER31_RS01590	ENOG4107WUY	phosphate acetyltransferase
HER31_RS01595	ENOG4108PFF	ethanolamine utilization cobalamin adenosyltransferase
HER31_RS01600	ENOG4105NDK	ethanolamine utilization protein
HER31_RS01610	ENOG4108VJN	May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place
HER31_RS01620	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
HER31_RS01630	ENOG4105CEN	a g-specific adenine glycosylase
HER31_RS01635	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HER31_RS01655	ENOG4105JQN	Transcriptional regulator
HER31_RS01665	ENOG4105CSA	Coproporphyrinogen iii oxidase
HER31_RS01670	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HER31_RS01685	ENOG4105VZ9	UPF0235 protein
HER31_RS01690	ENOG4108VIA	integral membrane protein
HER31_RS01695	ENOG4105II7	pyrroline-5-carboxylate reductase
HER31_RS01700	ENOG4105DFA	alanine racemase domain protein
HER31_RS01705	ENOG4105CZX	twitching motility protein
HER31_RS01710	ENOG4105CZX	twitching motility protein
HER31_RS01735	ENOG4105EFX	secretion protein, HlyD family
HER31_RS01740	ENOG4105HEE	Binding Domain protein
HER31_RS01745	ENOG4105CUW	cytochrome C-TYPE protein
HER31_RS01760	ENOG4105CC0	LysR family Transcriptional regulator
HER31_RS01765	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HER31_RS01770	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
HER31_RS01780	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
HER31_RS01790	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HER31_RS01795	ENOG4105DKQ	ROK family
HER31_RS01810	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
HER31_RS01870	ENOG4105D5G	Transposase
HER31_RS01935	ENOG4105V2T	cytochrome C
HER31_RS01940	ENOG41062JF	Transcriptional regulator
HER31_RS01970	ENOG4105CHR	reductase
HER31_RS02015	ENOG4105VJY	transcriptional regulator
HER31_RS02025	ENOG4105FB9	CRISPR-associated protein
HER31_RS02045	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
HER31_RS02070	ENOG4107QY8	reductase
HER31_RS02075	ENOG4105QAX	Iron-sulfur
HER31_RS02080	ENOG4108NEM	leader-binding protein dmsD
HER31_RS02100	ENOG4108IG5	Transcriptional regulator
HER31_RS02125	ENOG4108MR7	Arylsulfotransferase
HER31_RS02130	ENOG4105EJC	lysr family transcriptional regulator
HER31_RS02135	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
HER31_RS02150	ENOG4105CGZ	zinc metallopeptidase
HER31_RS02160	ENOG4105CYM	Glutathione S-transferase
HER31_RS02165	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HER31_RS02185	ENOG4105CYM	Glutathione S-transferase
HER31_RS02205	ENOG4105HEI	LysR family (Transcriptional regulator
HER31_RS02215	ENOG4105EUZ	Beta-lactamase domain protein
HER31_RS02225	ENOG4105EYW	Ion transport protein
HER31_RS02245	ENOG4108JQ2	peptide transport system atp-binding protein
HER31_RS02250	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
HER31_RS02255	ENOG4108EU3	peptide transport system, permease
HER31_RS02260	ENOG4108EKA	peptide transport system, permease
HER31_RS02265	ENOG4105DEF	Extracellular solute-binding protein, family 5
HER31_RS02270	ENOG4105E51	psp operon transcriptional activator
HER31_RS02275	ENOG41087YS	Phage shock protein A
HER31_RS02285	ENOG4105FM1	phage shock protein C
HER31_RS02290	ENOG4105CM6	amino acid regulated cytosolic protein
HER31_RS02295	ENOG4106K28	UPF0283 membrane protein
HER31_RS02300	ENOG4105C28	cystathionine
HER31_RS02305	ENOG4105MIR	Phenylalanine 4-monooxygenase
HER31_RS02310	ENOG41090A4	Pterin carbinolamine dehydratase
HER31_RS02320	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
HER31_RS02330	ENOG4108RXX	maleylacetoacetate isomerase
HER31_RS02335	ENOG4105C5Q	Transcriptional regulator
HER31_RS02465	ENOG4108UJV	acyl-CoA thioesterase i
HER31_RS02470	ENOG4108I0Y	(ABC) transporter
HER31_RS02475	ENOG4105CV6	ABC transporter, permease
HER31_RS02480	ENOG4105ECP	epimerase
HER31_RS02485	ENOG4105KKP	D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
HER31_RS02490	ENOG4105DSF	transport protein
HER31_RS02495	ENOG4105DR4	Methyltransferase
HER31_RS02505	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HER31_RS02535	ENOG4108DNC	Involved in acetate metabolism (By similarity)
HER31_RS02540	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HER31_RS02550	ENOG4105F1A	Pyruvate formate-lyase
HER31_RS02555	ENOG4105C6N	Formate acetyltransferase
HER31_RS02570	ENOG4108IA2	Sodium pantothenate symporter
HER31_RS02580	ENOG4105CGK	Exodeoxyribonuclease III
HER31_RS02585	ENOG4105K9H	YciI-like protein
HER31_RS02590	ENOG4105FCD	Major Facilitator
HER31_RS02595	ENOG4107835	probably involved in intracellular septation (By similarity)
HER31_RS02600	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HER31_RS02605	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HER31_RS02610	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HER31_RS02620	ENOG4105DDQ	anthranilate synthase
HER31_RS02625	ENOG4105CRQ	synthase (Component I)
HER31_RS02630	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
HER31_RS02635	ENOG4105DB7	PHP domain protein
HER31_RS02640	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HER31_RS02645	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HER31_RS02650	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HER31_RS02660	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
HER31_RS02665	ENOG4105UBK	short-chain dehydrogenase reductase
HER31_RS02675	ENOG4105ERU	peptidase
HER31_RS02680	ENOG4105CK2	sodium dicarboxylate symporter
HER31_RS02685	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
HER31_RS02690	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HER31_RS02700	ENOG4107R11	Transcriptional regulator
HER31_RS02705	ENOG4105EJQ	L-serine dehydratase
HER31_RS02710	ENOG4105D0Y	UPF0227 protein
HER31_RS02720	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
HER31_RS02730	ENOG4105E18	UPF0276 protein
HER31_RS02740	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HER31_RS02745	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HER31_RS02750	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HER31_RS02755	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HER31_RS02760	ENOG41088T4	Helicase IV
HER31_RS02770	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HER31_RS02775	ENOG4108Z1B	Cyclase dehydrase
HER31_RS02785	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HER31_RS02790	ENOG4105C0A	alcohol dehydrogenase
HER31_RS02795	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HER31_RS02800	ENOG4108W6C	Dehydrogenase
HER31_RS02805	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HER31_RS02810	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HER31_RS02820	ENOG4105EMU	Dehydrogenase
HER31_RS02825	ENOG4106NZI	LysR family Transcriptional regulator
HER31_RS02835	ENOG4105CFG	Acts as a chaperone (By similarity)
HER31_RS02840	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HER31_RS02850	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HER31_RS02855	ENOG4105D0M	Protease HtpX homolog
HER31_RS02860	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HER31_RS02865	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HER31_RS02870	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HER31_RS02875	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HER31_RS02880	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HER31_RS02890	ENOG4105HBR	Rna-binding protein
HER31_RS02895	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HER31_RS02900	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HER31_RS02905	ENOG4105EEI	dihydropteroate synthase
HER31_RS02910	ENOG4105CP7	Triose-phosphate isomerase
HER31_RS02915	ENOG4105NTZ	Preprotein translocase subunit SecG
HER31_RS02935	ENOG4105CHV	Transcription elongation factor NusA
HER31_RS02940	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HER31_RS02950	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HER31_RS02955	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HER31_RS02960	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HER31_RS02980	ENOG4105CE4	GlcNAc 6-P deacetylase
HER31_RS02995	ENOG4105EYA	deoxyribonuclease
HER31_RS03000	ENOG4105D9N	nucleoside
HER31_RS03010	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HER31_RS03020	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
HER31_RS03025	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HER31_RS03035	ENOG4105EAC	phosphoserine phosphatase
HER31_RS03045	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HER31_RS03060	ENOG4105BZU	Histidine kinase
HER31_RS03070	ENOG4105C0Z	ABC transporter
HER31_RS03075	ENOG4105CEY	Amp-dependent synthetase and ligase
HER31_RS03095	ENOG4108IV0	ABC, transporter
HER31_RS03110	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HER31_RS03115	ENOG4108JU5	Magnesium and cobalt efflux protein
HER31_RS03120	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HER31_RS03125	ENOG4105C9A	Phoh family
HER31_RS03130	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HER31_RS03135	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HER31_RS03150	ENOG4105FQ6	thiopurine methyltransferase
HER31_RS03155	ENOG4105BZU	Histidine kinase
HER31_RS03160	ENOG4105ETX	regulatoR
HER31_RS03175	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HER31_RS03190	ENOG4108VA1	ABC transporter
HER31_RS03195	ENOG4107T9Q	phosphonate abc transporter
HER31_RS03200	ENOG4108UYB	regulatoR
HER31_RS03215	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
HER31_RS03225	ENOG4108JA2	transcriptioN-repair coupling factor
HER31_RS03235	ENOG4105D60	lipoprotein releasing system transmembrane protein
HER31_RS03240	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HER31_RS03245	ENOG4105D60	lipoprotein releasing system transmembrane protein
HER31_RS03250	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
HER31_RS03265	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
HER31_RS03270	ENOG4105BZ1	(ABC) transporter
HER31_RS03275	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HER31_RS03280	ENOG4105W49	UPF0434 protein
HER31_RS03285	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HER31_RS03295	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HER31_RS03315	ENOG4105BZN	citrate synthase
HER31_RS03320	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
HER31_RS03325	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
HER31_RS03330	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HER31_RS03335	ENOG4105E33	succinate dehydrogenase
HER31_RS03340	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HER31_RS03345	ENOG4105C7S	Dehydrogenase
HER31_RS03350	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HER31_RS03355	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HER31_RS03365	ENOG4105C8Q	Methyl-accepting chemotaxis
HER31_RS03380	ENOG4105CKU	formyltetrahydrofolate synthetase
HER31_RS03400	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HER31_RS03405	ENOG4105C5X	domain protein
HER31_RS03415	ENOG4105BZW	Glycerate kinase
HER31_RS03450	ENOG4105CUW	cytochrome C-TYPE protein
HER31_RS03455	ENOG4105CX6	glutaminyL-tRNA synthetase
HER31_RS03460	ENOG4105CT3	Monooxygenase
HER31_RS03465	ENOG41090R7	Ferric uptake
HER31_RS03470	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HER31_RS03475	ENOG4105C8Y	Acetylornithine aminotransferase
HER31_RS03480	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HER31_RS03485	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HER31_RS03495	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HER31_RS03505	ENOG4105D0M	Protease HtpX homolog
HER31_RS03510	ENOG4106XZB	Cytochrome C3
HER31_RS03515	ENOG4106XZB	Cytochrome C3
HER31_RS03520	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HER31_RS03525	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
HER31_RS03535	ENOG4105E0X	reductase
HER31_RS03540	ENOG4105KJF	protein tyrosine phosphatase
HER31_RS03545	ENOG4105CZQ	inner membrane transport protein YdhC
HER31_RS03550	ENOG4105F52	Transcriptional regulator
HER31_RS03555	ENOG4105C03	ribonuclease
HER31_RS03560	ENOG4105EI2	Pseudouridine synthase
HER31_RS03565	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HER31_RS03575	ENOG4108UHJ	MAF-like protein
HER31_RS03580	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HER31_RS03585	ENOG4105VGS	50s ribosomal protein l32
HER31_RS03595	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HER31_RS03600	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HER31_RS03605	ENOG4105CHR	reductase
HER31_RS03610	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HER31_RS03615	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HER31_RS03620	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HER31_RS03625	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
HER31_RS03630	ENOG4105CJB	Exodeoxyribonuclease I
HER31_RS03635	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HER31_RS03640	ENOG4105F8C	transglutaminase domain-containing protein
HER31_RS03650	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HER31_RS03655	ENOG4107SC1	transglycosylase
HER31_RS03660	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HER31_RS03665	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
HER31_RS03675	ENOG4108YYI	Protein of unknown function (DUF2810)
HER31_RS03695	ENOG4105VYW	UPF0251 protein
HER31_RS03705	ENOG4105CSU	acyl-Coa dehydrogenase
HER31_RS03720	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HER31_RS03725	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HER31_RS03735	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HER31_RS03745	ENOG4105EMU	Dehydrogenase
HER31_RS03775	ENOG4105C3Q	Glycosyl transferase, family 2
HER31_RS03780	ENOG4107QW3	Sucrose phosphorylase
HER31_RS03785	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HER31_RS03800	ENOG4105CFU	surface antigen
HER31_RS03805	ENOG4105D44	asparaginase
HER31_RS03815	ENOG4105D7W	serine acetyltransferase
HER31_RS03855	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HER31_RS03860	ENOG4105C5H	ABC transporter
HER31_RS03865	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HER31_RS03880	ENOG4105EG6	Saccharopine dehydrogenase
HER31_RS03885	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HER31_RS03935	ENOG4107NA1	Endonuclease Exonuclease phosphatase
HER31_RS03940	ENOG4105C9K	Endothelin-converting enzyme 1
HER31_RS03950	ENOG4108IPJ	Membrane
HER31_RS03960	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HER31_RS03965	ENOG4105BZU	Histidine kinase
HER31_RS03970	ENOG41077A9	carbonic anhydrase
HER31_RS03985	ENOG4105K59	histidine triad (HIT) protein
HER31_RS04010	ENOG4108ESX	Receptor
HER31_RS04020	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
HER31_RS04045	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HER31_RS04050	ENOG41069NU	Nitroreductase
HER31_RS04070	ENOG4105HMI	Membrane
HER31_RS04085	ENOG4105C8U	phosphate abc transporter
HER31_RS04090	ENOG4105E2Z	phosphate ABC transporter (Permease
HER31_RS04095	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HER31_RS04105	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HER31_RS04130	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HER31_RS04135	ENOG4105DK2	UPF0207 protein
HER31_RS04140	ENOG4105CHM	Aminotransferase
HER31_RS04150	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
HER31_RS04155	ENOG4105NNH	LexA regulated protein
HER31_RS04165	ENOG4105EV9	Alpha Beta Hydrolase
HER31_RS04170	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
HER31_RS04175	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
HER31_RS04180	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
HER31_RS04185	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HER31_RS04190	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
HER31_RS04195	ENOG4107R0V	Pyruvate dehydrogenase
HER31_RS04200	ENOG4105CPP	Dehydrogenase, E1 component
HER31_RS04210	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HER31_RS04225	ENOG4105R8A	Heat shock protein
HER31_RS04235	ENOG4105CUJ	penicillin amidase
HER31_RS04240	ENOG4108UQ5	membrane protein YcdZ
HER31_RS04250	ENOG4105E68	Sulfatase
HER31_RS04260	ENOG4106V8H	Nucleoid-associated protein
HER31_RS04265	ENOG4105DWD	nucleoside recognition domain protein
HER31_RS04270	ENOG4105K8R	UPF0145 protein
HER31_RS04275	ENOG4105K8R	UPF0145 protein
HER31_RS04280	ENOG4105ERG	peptidase m48, ste24p
HER31_RS04295	ENOG4107QPN	acyl-Coa dehydrogenase
HER31_RS04300	ENOG4105E7A	Glutamine amidotransferase
HER31_RS04315	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
HER31_RS04340	ENOG4105BZU	Histidine kinase
HER31_RS04350	ENOG4105K56	Transcriptional regulator
HER31_RS04360	ENOG4106032	Glutathionylspermidine synthase
HER31_RS04365	ENOG4105F1G	UPF0441 protein
HER31_RS04405	ENOG4105CF7	AraC family transcriptional regulator
HER31_RS04425	ENOG4105CSM	endonuclease III
HER31_RS04430	ENOG4105DZB	Electron transport complex
HER31_RS04440	ENOG4105D6A	Electron transport complex
HER31_RS04445	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
HER31_RS04450	ENOG4108R3D	Electron transport complex
HER31_RS04455	ENOG4105DGN	Electron transport complex
HER31_RS04460	ENOG4107XTP	(EAL) domain protein
HER31_RS04475	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HER31_RS04480	ENOG4105EHG	Permease protein
HER31_RS04490	ENOG4106GFD	transport protein
HER31_RS04495	ENOG41090AP	transport protein
HER31_RS04505	ENOG4105D4P	Coproporphyrinogen iii oxidase
HER31_RS04510	ENOG41090JE	Utilization Protein
HER31_RS04515	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
HER31_RS04520	ENOG4105BZ1	(ABC) transporter
HER31_RS04565	ENOG4108MR7	Arylsulfotransferase
HER31_RS04580	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
HER31_RS04585	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HER31_RS04590	ENOG4107TDF	Formate hydrogenlyase subunit 4
HER31_RS04595	ENOG4105D65	subunit l
HER31_RS04600	ENOG4107WQX	hydrogenase 4 membrane subunit
HER31_RS04605	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HER31_RS04610	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HER31_RS04620	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
HER31_RS04625	ENOG4105I6X	formate hydrogenlyase maturation
HER31_RS04630	ENOG4108MG9	hydrogenase 3 maturation protease
HER31_RS04635	ENOG4108RC0	Electron transport protein
HER31_RS04645	ENOG4108JUA	Transcriptional regulator
HER31_RS04650	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HER31_RS04655	ENOG4105TMB	Formate nitrite transporter
HER31_RS04665	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
HER31_RS04670	ENOG4105EM7	Selenocysteine-specific translation elongation factor
HER31_RS04675	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
HER31_RS04765	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HER31_RS04770	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HER31_RS04775	ENOG4105EHG	Permease protein
HER31_RS04780	ENOG4108YZT	Adenosylcobinamide kinase
HER31_RS04785	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HER31_RS04795	ENOG4105CVJ	phosphoglycerate mutase
HER31_RS04805	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HER31_RS04810	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HER31_RS04815	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
HER31_RS04820	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HER31_RS04825	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HER31_RS04840	ENOG4108UQV	Membrane
HER31_RS04870	ENOG4105CR8	Transcriptional regulator
HER31_RS04880	ENOG4107EFR	Flavocytochrome c
HER31_RS04935	ENOG4105QAX	Iron-sulfur
HER31_RS04940	ENOG4107QY8	reductase
HER31_RS04945	ENOG4108NEM	leader-binding protein dmsD
HER31_RS04950	ENOG4105QAX	Iron-sulfur
HER31_RS04955	ENOG4107QY8	reductase
HER31_RS04975	ENOG4105QAX	Iron-sulfur
HER31_RS04980	ENOG4107QY8	reductase
HER31_RS05000	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
HER31_RS05005	ENOG4105EFT	decarboxylase
HER31_RS05015	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
HER31_RS05020	ENOG41081F0	Precorrin-8x methylmutase
HER31_RS05025	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
HER31_RS05030	ENOG4105DVK	Precorrin-2 c20-methyltransferase
HER31_RS05035	ENOG4108P62	biosynthesis protein (CbiG)
HER31_RS05045	ENOG4107PPM	cobalt chelatase
HER31_RS05050	ENOG4105E4R	Precorrin-3B C17-methyltransferase
HER31_RS05055	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
HER31_RS05060	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HER31_RS05065	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HER31_RS05070	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HER31_RS05075	ENOG4107RRN	ABC transporter substrate-binding protein
HER31_RS05080	ENOG4105C3U	ABC transporter
HER31_RS05090	ENOG4107R73	Mate efflux family protein
HER31_RS05170	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HER31_RS05185	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HER31_RS05195	ENOG4105VRT	cytoplasmic protein
HER31_RS05235	ENOG4105BZU	Histidine kinase
HER31_RS05255	ENOG4105WH1	Two component transcriptional regulator luxr family
HER31_RS05260	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HER31_RS05320	ENOG4105E09	nadh pyrophosphatase
HER31_RS05325	ENOG41082IR	Excinuclease ABC C subunit domain protein
HER31_RS05330	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
HER31_RS05345	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HER31_RS05350	ENOG4108XFH	Transcriptional regulator
HER31_RS05355	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HER31_RS05375	ENOG4107YD3	Thioesterase
HER31_RS05380	ENOG4105E02	MotA TolQ exbB proton channel
HER31_RS05385	ENOG4105M8F	Biopolymer transport protein exbD tolR
HER31_RS05395	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HER31_RS05400	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HER31_RS05405	ENOG4105UFD	tol-pal system protein YbgF
HER31_RS05475	ENOG4105K64	Glycosyl transferase, family 2
HER31_RS05480	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HER31_RS05485	ENOG4105BZU	Histidine kinase
HER31_RS05525	ENOG4108SHN	Glycosyl transferase, family 2
HER31_RS05545	ENOG41090BQ	Glutaredoxin
HER31_RS05550	ENOG4105CFI	type iii restriction protein res subunit
HER31_RS05555	ENOG4105D3Y	Na H antiporter
HER31_RS05560	ENOG4105D3R	alkyl hydroperoxide reductase
HER31_RS05570	ENOG4105EIY	sodium-type flagellar protein motY
HER31_RS05575	ENOG4105CD3	dihydroorotase
HER31_RS05585	ENOG4105C87	Aminotransferase class I and II
HER31_RS05595	ENOG4108RE9	Phosphodiesterase
HER31_RS05605	ENOG4105VEQ	Cold shock protein
HER31_RS05610	ENOG4105VEQ	Cold shock protein
HER31_RS05615	ENOG4105DR4	Methyltransferase
HER31_RS05620	ENOG4106371	Methyltransferase
HER31_RS05645	ENOG4105DR5	peptidase
HER31_RS05655	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HER31_RS05660	ENOG4105BZU	Histidine kinase
HER31_RS05675	ENOG4105DIH	basic membrane
HER31_RS05680	ENOG4108JQ9	ABC transporter
HER31_RS05695	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
HER31_RS05710	ENOG4105CY0	Metallo-Beta-Lactamase
HER31_RS05735	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HER31_RS05740	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HER31_RS05745	ENOG4105CQB	FAD linked oxidase domain protein
HER31_RS05755	ENOG4105ETT	transcriptional Regulator, LysR family
HER31_RS05770	ENOG4107R1I	NAD-dependent malic enzyme
HER31_RS05785	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HER31_RS05790	ENOG4105BZS	acriflavin resistance protein
HER31_RS05795	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HER31_RS05825	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HER31_RS05830	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HER31_RS05840	ENOG4105E3S	small subunit
HER31_RS05845	ENOG4105DPX	Hydrogenase, large subunit
HER31_RS05850	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
HER31_RS05855	ENOG4108USZ	hydrogenase
HER31_RS05860	ENOG4108P97	
HER31_RS05865	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
HER31_RS05870	ENOG4105C8H	hydrogenase maturation protein Hypf
HER31_RS05880	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
HER31_RS05885	ENOG4107RSS	Hydrogenase accessory protein HypB
HER31_RS05895	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HER31_RS05900	ENOG4105BZG	amino acid carrier protein
HER31_RS05915	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HER31_RS05920	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HER31_RS05930	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HER31_RS05935	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
HER31_RS05940	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
HER31_RS05965	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HER31_RS05990	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HER31_RS06000	ENOG4108IEG	Formate dehydrogenase Alpha subunit
HER31_RS06005	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
HER31_RS06015	ENOG4108UT2	hemolysin iii
HER31_RS06025	ENOG4105MEW	serine threonine protein phosphatase
HER31_RS06030	ENOG4105G6Z	alkaline phosphatase
HER31_RS06035	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HER31_RS06040	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HER31_RS06095	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HER31_RS06115	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HER31_RS06130	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
HER31_RS06135	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HER31_RS06155	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
HER31_RS06160	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
HER31_RS06165	ENOG4108MN8	Membrane
HER31_RS06180	ENOG4105C8U	phosphate abc transporter
HER31_RS06185	ENOG4105E2Z	phosphate ABC transporter (Permease
HER31_RS06190	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HER31_RS06195	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
HER31_RS06200	ENOG4105C1J	atp-dependent rna helicase
HER31_RS06215	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HER31_RS06220	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HER31_RS06225	ENOG4105EHG	Permease protein
HER31_RS06230	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HER31_RS06235	ENOG4108JJ7	ABC transporter
HER31_RS06245	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
HER31_RS06255	ENOG4105D9P	serine threonine protein kinase
HER31_RS06260	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HER31_RS06285	ENOG4105BZU	Histidine kinase
HER31_RS06320	ENOG4105SKE	transcriptional Regulator LysR family
HER31_RS06325	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HER31_RS06330	ENOG4105CTD	carboxy-peptidase
HER31_RS06350	ENOG4107QI1	Mate efflux family protein
HER31_RS06355	ENOG4108R6K	riboflavin synthase, subunit alpha
HER31_RS06375	ENOG4105C22	threonyL-tRNA synthetase
HER31_RS06380	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HER31_RS06385	ENOG41082NX	50s ribosomal protein l35
HER31_RS06390	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HER31_RS06405	ENOG4105C5I	Dehydrogenase
HER31_RS06410	ENOG4107QNR	UPF0135 protein
HER31_RS06420	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HER31_RS06440	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
HER31_RS06480	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HER31_RS06485	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HER31_RS06490	ENOG4105D1F	ATP-binding protein
HER31_RS06495	ENOG4105DBI	uridine monophosphokinase
HER31_RS06510	ENOG4105HHA	aminodeoxychorismate lyase
HER31_RS06515	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HER31_RS06520	ENOG4107QRG	dna polymerase iii
HER31_RS06530	ENOG4105F8V	Hydrolase, tatD family
HER31_RS06535	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HER31_RS06540	ENOG4108JIC	nucleoside recognition domain protein
HER31_RS06545	ENOG4105DY2	Paraquat-inducible protein b
HER31_RS06550	ENOG4105H2K	paraquat-inducible protein a
HER31_RS06555	ENOG4105F1S	paraquat-inducible protein a
HER31_RS06570	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
HER31_RS06575	ENOG4105CN1	protease
HER31_RS06580	ENOG4105C8J	)-transporter
HER31_RS06585	ENOG4105CD8	aminopeptidase N
HER31_RS06600	ENOG4105D25	secreted protein
HER31_RS06610	ENOG4107R13	MMPL domain protein
HER31_RS06615	ENOG4105C7I	Dehydrogenase
HER31_RS06620	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HER31_RS06625	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
HER31_RS06630	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HER31_RS06640	ENOG4105C5H	ABC transporter
HER31_RS06650	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
HER31_RS06655	ENOG4108V06	Glutathione peroxidase
HER31_RS06660	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
HER31_RS06665	ENOG4105DAN	ATP-dependent protease
HER31_RS06695	ENOG4105EGS	Mechanosensitive ion channel
HER31_RS06705	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
HER31_RS06730	ENOG4105C59	p-type ATPase
HER31_RS06745	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HER31_RS06750	ENOG4105Q9Y	Universal stress protein
HER31_RS06755	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HER31_RS06780	ENOG4105D38	putrescine abc transporter
HER31_RS06785	ENOG4108HM4	ABC transporter
HER31_RS06790	ENOG4105CGF	Aromatic amino acid aminotransferase
HER31_RS06815	ENOG4105JIM	Phosphatidylserine synthase
HER31_RS06820	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
HER31_RS06830	ENOG4105CSU	acyl-Coa dehydrogenase
HER31_RS06835	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
HER31_RS06840	ENOG4105CFV	Tetratricopeptide repeat protein
HER31_RS06850	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HER31_RS06855	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HER31_RS06860	ENOG4105CAT	Cytidine monophosphate kinase
HER31_RS06865	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HER31_RS06870	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HER31_RS06875	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HER31_RS06880	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HER31_RS06885	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HER31_RS06890	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HER31_RS06895	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HER31_RS06900	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HER31_RS06905	ENOG4105XPH	Ferredoxin
HER31_RS06920	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HER31_RS06925	ENOG4105D07	Signal peptide peptidase, SppA
HER31_RS06930	ENOG4105HDK	L-asparaginase
HER31_RS06935	ENOG4105VUT	cytoplasmic protein
HER31_RS06955	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HER31_RS07000	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HER31_RS07005	ENOG4105EGI	Transcriptional regulator
HER31_RS07025	ENOG4108UHU	Aldolase
HER31_RS07030	ENOG4105C01	Dihydroxy-acid dehydratase
HER31_RS07035	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
HER31_RS07040	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HER31_RS07045	ENOG4106KNT	transcriptional regulator
HER31_RS07050	ENOG4105CA9	Pyruvate kinase
HER31_RS07055	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HER31_RS07060	ENOG4105WMR	Protein CrcB homolog
HER31_RS07065	ENOG4105D1H	recombination factor protein RarA
HER31_RS07075	ENOG4105CNU	cell division protein FtsK
HER31_RS07080	ENOG4105EW9	transcriptional regulator AsnC family
HER31_RS07085	ENOG4105DCF	alanine dehydrogenase
HER31_RS07090	ENOG4105C3M	thioredoxin reductase
HER31_RS07095	ENOG4108JJ9	ABC, transporter
HER31_RS07100	ENOG4108JJ8	(ABC) transporter
HER31_RS07110	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HER31_RS07115	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
HER31_RS07120	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HER31_RS07125	ENOG4105MRR	Transcriptional regulator (By similarity)
HER31_RS07130	ENOG4105DEF	Extracellular solute-binding protein, family 5
HER31_RS07140	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HER31_RS07145	ENOG4108JQ5	ABC transporter
HER31_RS07150	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HER31_RS07155	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HER31_RS07160	ENOG4105VEQ	Cold shock protein
HER31_RS07165	ENOG4108HMX	isocitrate dehydrogenase (NADP)
HER31_RS07170	ENOG4108R99	pseudouridine synthase
HER31_RS07175	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HER31_RS07180	ENOG41075W9	High frequency lysogenization protein HflD homolog
HER31_RS07185	ENOG4107QTF	adenylosuccinate lyase
HER31_RS07190	ENOG4105EZE	Cupin 4 family protein
HER31_RS07200	ENOG4107RDP	Dehydrogenase
HER31_RS07205	ENOG4108RMJ	sensory transduction regulator
HER31_RS07215	ENOG4108UYE	Lactoylglutathione lyase
HER31_RS07240	ENOG4105DR9	pseudouridine synthase
HER31_RS07255	ENOG4109015	Biopolymer transport protein exbD tolR
HER31_RS07275	ENOG4105CI2	imidazolone-5-propionate hydrolase
HER31_RS07290	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HER31_RS07310	ENOG4105C8Q	Methyl-accepting chemotaxis
HER31_RS07315	ENOG4105C8Q	Methyl-accepting chemotaxis
HER31_RS07320	ENOG4105CQ7	ATP-dependent helicase
HER31_RS07325	ENOG4105EUJ	GTP cyclohydrolase i
HER31_RS07335	ENOG4105F1J	Homogentisate 1,2-dioxygenase
HER31_RS07345	ENOG4108B1Q	Ribonuclease
HER31_RS07350	ENOG4105C0A	alcohol dehydrogenase
HER31_RS07355	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
HER31_RS07360	ENOG4105D9U	N-acetyltransferase
HER31_RS07370	ENOG4105X5C	UPF0181 protein
HER31_RS07405	ENOG4105C8Q	Methyl-accepting chemotaxis
HER31_RS07420	ENOG4108R5S	membrane
HER31_RS07425	ENOG4105BZU	Histidine kinase
HER31_RS07430	ENOG4105BZ1	(ABC) transporter
HER31_RS07435	ENOG4105BZ1	(ABC) transporter
HER31_RS07445	ENOG4105CRQ	synthase (Component I)
HER31_RS07450	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HER31_RS07455	ENOG4105P8F	nudix hydrolase
HER31_RS07475	ENOG4105CJ2	(LipO)protein
HER31_RS07490	ENOG4105VXR	cytoplasmic protein
HER31_RS07500	ENOG4105M2J	Glutaredoxin
HER31_RS07505	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HER31_RS07510	ENOG4105CYN	Serine protein kinase
HER31_RS07515	ENOG4106AKX	UPF0229 protein
HER31_RS07520	ENOG4105ED1	spovr family
HER31_RS07535	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HER31_RS07540	ENOG4108ZZ3	UPF0260 protein
HER31_RS07545	ENOG4105CVE	Lytic murein transglycosylase
HER31_RS07550	ENOG4105VNG	YcgL domain-containing protein
HER31_RS07555	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HER31_RS07560	ENOG4107QMS	site-determining protein
HER31_RS07565	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HER31_RS07570	ENOG4105CEY	Amp-dependent synthetase and ligase
HER31_RS07575	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
HER31_RS07580	ENOG4105CEY	Amp-dependent synthetase and ligase
HER31_RS07600	ENOG41072GX	Peptidase M22 Glycoprotease
HER31_RS07605	ENOG4105DVT	helicase
HER31_RS07610	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HER31_RS07615	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HER31_RS07620	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HER31_RS07625	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HER31_RS07630	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HER31_RS07635	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HER31_RS07640	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HER31_RS07645	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HER31_RS07655	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HER31_RS07660	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HER31_RS07665	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HER31_RS07670	ENOG4108N3W	hemolysin secretion protein
HER31_RS07690	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
HER31_RS07710	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HER31_RS07715	ENOG4105DUM	transcriptional regulator, lysR family
HER31_RS07725	ENOG4105BZ1	(ABC) transporter
HER31_RS07735	ENOG4105X2V	dna damage-inducible protein
HER31_RS07745	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HER31_RS07750	ENOG410804D	Sensor Signal Transduction Histidine Kinase
HER31_RS07770	ENOG4105DTJ	flagellar hook-associated protein
HER31_RS07775	ENOG4105E1Q	flagellar hook-associated protein
HER31_RS07780	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HER31_RS07785	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HER31_RS07790	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HER31_RS07795	ENOG4105CGA	flagellar basal-body rod protein FlgG
HER31_RS07800	ENOG4108KPB	Flagellar basal-body rod protein FlgF
HER31_RS07805	ENOG4105BZE	flagellar hook protein, FlgE
HER31_RS07815	ENOG4108ZC9	flagellar basal-body rod protein flgc
HER31_RS07820	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HER31_RS07830	ENOG4105DD5	Flagellar motor switch protein
HER31_RS07840	ENOG4105ER2	Ompa motb domain protein
HER31_RS07845	ENOG4107RD7	Flagellar Motor Protein, MotA
HER31_RS07870	ENOG4105MQ3	flagellar protein FliS
HER31_RS07875	ENOG4105DTS	flagellar hook-associated
HER31_RS07880	ENOG4105I03	Flagellin
HER31_RS07900	ENOG4108JIR	Flagellum-specific ATP synthase
HER31_RS07910	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HER31_RS07915	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HER31_RS07920	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
HER31_RS07930	ENOG4105UYK	outer membrane protein a
HER31_RS07955	ENOG4105CN7	Flagellar biosynthetic protein FliP
HER31_RS07960	ENOG4105VS8	Flagellar biosynthetic protein fliq
HER31_RS07965	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HER31_RS07970	ENOG4105D00	flagellar biosynthetic protein flhB
HER31_RS08000	ENOG4108Z3N	Transcriptional regulator
HER31_RS08050	ENOG4107RZZ	dna polymerase iii epsilon subunit
HER31_RS08055	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HER31_RS08060	ENOG4105D1A	Methyltransferase
HER31_RS08065	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HER31_RS08070	ENOG4105E9H	Lytic Murein transglycosylase
HER31_RS08075	ENOG4108SDH	ABC, transporter
HER31_RS08080	ENOG4108IUW	ABC transporter
HER31_RS08100	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HER31_RS08110	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HER31_RS08170	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HER31_RS08180	ENOG4108UMI	ABC transporter, permease
HER31_RS08185	ENOG4105D01	(LipO)protein
HER31_RS08190	ENOG4108V0P	LemA family
HER31_RS08195	ENOG4105D0M	Protease HtpX homolog
HER31_RS08200	ENOG4105DSB	aldose 1-epimerase
HER31_RS08210	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HER31_RS08225	ENOG4108IRC	dna polymerase iii
HER31_RS08230	ENOG4105C2X	Arabinose 5-phosphate isomerase
HER31_RS08250	ENOG4107QN1	sodium solute
HER31_RS08270	ENOG4107SRH	Nad-dependent epimerase dehydratase
HER31_RS08275	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HER31_RS08280	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
HER31_RS08285	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HER31_RS08290	ENOG4105EXN	Sulfate transport protein CysZ
HER31_RS08305	ENOG4108J2P	Alpha beta hydrolase fold
HER31_RS08325	ENOG4105C6T	cysteine synthase
HER31_RS08330	ENOG4105KZ7	phosphocarrier protein hpr
HER31_RS08335	ENOG4105C5Y	PTS System
HER31_RS08340	ENOG4105KUZ	arsenate reductase
HER31_RS08345	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HER31_RS08355	ENOG4105D6S	protein involved in catabolism of external DNA
HER31_RS08370	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
HER31_RS08390	ENOG4107QYX	exodeoxyribonuclease v alpha
HER31_RS08395	ENOG4107QKA	exodeoxyribonuclease V beta
HER31_RS08400	ENOG4105DSY	exodeoxyribonuclease V, gamma
HER31_RS08405	ENOG4105DUX	Transporter
HER31_RS08415	ENOG4105HEI	LysR family (Transcriptional regulator
HER31_RS08440	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HER31_RS08475	ENOG4105BZS	acriflavin resistance protein
HER31_RS08485	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HER31_RS08490	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HER31_RS08495	ENOG4105RH4	Glycine cleavage system transcriptional repressor
HER31_RS08500	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HER31_RS08520	ENOG4105ERG	peptidase m48, ste24p
HER31_RS08545	ENOG4108WUH	Transcriptional regulator, TetR family
HER31_RS08555	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HER31_RS08560	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HER31_RS08575	ENOG4105HEI	LysR family (Transcriptional regulator
HER31_RS08595	ENOG4105C2W	permease
HER31_RS08600	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HER31_RS08605	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HER31_RS08610	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HER31_RS08615	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HER31_RS08620	ENOG4108JQB	penicillin-binding protein 1C
HER31_RS08625	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
HER31_RS08635	ENOG4107QRI	Phosphoketolase
HER31_RS08645	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
HER31_RS08660	ENOG4105CAQ	asparagine synthetase
HER31_RS08670	ENOG4105EEQ	Na H antiporter
HER31_RS08675	ENOG4108Z66	YbaK ebsC protein
HER31_RS08680	ENOG4105MVE	transcriptional regulator
HER31_RS08685	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HER31_RS08690	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HER31_RS08715	ENOG4105CXT	aspartate transcarbamylase
HER31_RS08720	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
HER31_RS08725	ENOG4105MSB	protein, conserved in bacteria
HER31_RS08730	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
HER31_RS08740	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HER31_RS08745	ENOG4105CSU	acyl-Coa dehydrogenase
HER31_RS08750	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
HER31_RS08760	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
HER31_RS08770	ENOG4106428	Protein of unknown function (DUF2496)
HER31_RS08780	ENOG4105N1F	Hnh endonuclease
HER31_RS08820	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HER31_RS08825	ENOG4105BZU	Histidine kinase
HER31_RS08830	ENOG4105CJ2	(LipO)protein
HER31_RS08835	ENOG4107EFR	Flavocytochrome c
HER31_RS08855	ENOG4105CQB	FAD linked oxidase domain protein
HER31_RS08860	ENOG4105DAA	L-lactate
HER31_RS08865	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HER31_RS08870	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HER31_RS08875	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HER31_RS08880	ENOG4105BZU	Histidine kinase
HER31_RS08885	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HER31_RS08890	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HER31_RS08895	ENOG4105N21	Membrane
HER31_RS08900	ENOG4105CUT	histidyl-tRNA synthetase
HER31_RS08905	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HER31_RS08910	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
HER31_RS08920	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HER31_RS08930	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HER31_RS08940	ENOG4105WVQ	Fe-S assembly protein IscX
HER31_RS08945	ENOG4108ZIT	Ferredoxin, 2FE-2S
HER31_RS08950	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
HER31_RS08955	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
HER31_RS08960	ENOG4108Z4V	iron-sulfur cluster assembly
HER31_RS08965	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
HER31_RS08970	ENOG4105C3J	Cysteine desulfurase
HER31_RS08975	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HER31_RS08985	ENOG4105ECY	inositol monophosphatase
HER31_RS09005	ENOG4108HRK	Histidine kinase
HER31_RS09010	ENOG4108NEV	two component transcriptional regulator, LytTR family
HER31_RS09015	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HER31_RS09030	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HER31_RS09040	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HER31_RS09045	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HER31_RS09050	ENOG4105VIE	preprotein translocase, subunit YajC
HER31_RS09055	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HER31_RS09060	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HER31_RS09075	ENOG4107RET	Isocitrate lyase
HER31_RS09080	ENOG4107QP3	malate synthase g
HER31_RS09085	ENOG4105CSR	polyphosphate kinase 2
HER31_RS09100	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HER31_RS09105	ENOG4105BZU	Histidine kinase
HER31_RS09110	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HER31_RS09115	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HER31_RS09120	ENOG4105E2Z	phosphate ABC transporter (Permease
HER31_RS09125	ENOG4105C8U	phosphate abc transporter
HER31_RS09130	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HER31_RS09135	ENOG4105C9X	ppx gppa phosphatase
HER31_RS09140	ENOG4105DJH	phosphate
HER31_RS09145	ENOG4105BZU	Histidine kinase
HER31_RS09150	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HER31_RS09160	ENOG4105DH7	May be involved in recombination (By similarity)
HER31_RS09170	ENOG4105BZU	Histidine kinase
HER31_RS09175	ENOG4105EWT	decarboxylase family
HER31_RS09180	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
HER31_RS09185	ENOG4108RU0	short-chain dehydrogenase reductase
HER31_RS09195	ENOG4108MR7	Arylsulfotransferase
HER31_RS09215	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
HER31_RS09225	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HER31_RS09230	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HER31_RS09250	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
HER31_RS09265	ENOG4105ETT	transcriptional Regulator, LysR family
HER31_RS09275	ENOG410624X	efflux transporter, rnd family, mfp subunit
HER31_RS09280	ENOG4105BZS	acriflavin resistance protein
HER31_RS09285	ENOG4105JQN	Transcriptional regulator
HER31_RS09315	ENOG4105DZP	Membrane-associated zinc metalloprotease
HER31_RS09320	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HER31_RS09360	ENOG4105FDK	ABC transporter
HER31_RS09365	ENOG41080V6	ABC-3 protein
HER31_RS09375	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HER31_RS09405	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HER31_RS09415	ENOG4108YY7	Invasion gene expression up-regulator SirB
HER31_RS09420	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HER31_RS09425	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HER31_RS09430	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HER31_RS09440	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HER31_RS09450	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HER31_RS09455	ENOG4105CGH	5'-nucleotidase
HER31_RS09460	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HER31_RS09465	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HER31_RS09470	ENOG4105C3G	gtp-binding protein
HER31_RS09540	ENOG4108JGH	Tetr family transcriptional regulator
HER31_RS09550	ENOG4105BZS	acriflavin resistance protein
HER31_RS09560	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HER31_RS09565	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HER31_RS09605	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HER31_RS09610	ENOG4108Z6B	deaminase
HER31_RS09625	ENOG4105E18	UPF0276 protein
HER31_RS09640	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HER31_RS09645	ENOG4105ETE	Transcriptional regulator (LacI family
HER31_RS09650	ENOG4108RVA	ribokinase
HER31_RS09655	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HER31_RS09660	ENOG4105CNN	ABC, transporter
HER31_RS09665	ENOG4105C2J	ABC transporter
HER31_RS09670	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
HER31_RS09675	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HER31_RS09710	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HER31_RS09715	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
HER31_RS09720	ENOG4105C1J	atp-dependent rna helicase
HER31_RS09730	ENOG4105CHR	reductase
HER31_RS09740	ENOG4107QR9	Iron-sulfur cluster binding protein
HER31_RS09745	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HER31_RS09750	ENOG4107RE1	Inosine-guanosine kinase
HER31_RS09760	ENOG4107R7A	Allophanate hydrolase subunit 2
HER31_RS09765	ENOG4105E7W	lamb ycsf family protein
HER31_RS09785	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HER31_RS09790	ENOG4105BZU	Histidine kinase
HER31_RS09805	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HER31_RS09810	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HER31_RS09815	ENOG4107QR8	Thioredoxin
HER31_RS09820	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HER31_RS09845	ENOG4105P8Q	Curli production assembly transport component CsgG
HER31_RS09860	ENOG41086KC	Transcriptional regulator
HER31_RS09865	ENOG4107RH8	nuclease SbcCD subunit D
HER31_RS09870	ENOG4105EYH	Exonuclease
HER31_RS09875	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HER31_RS09880	ENOG4108UJU	UPF0301 protein
HER31_RS09885	ENOG4108ZJT	translation initiation factor, Sui1
HER31_RS09905	ENOG4105EIN	peptidylprolyl cis-trans isomerase
HER31_RS09910	ENOG4105K70	DNA-binding protein
HER31_RS09915	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HER31_RS09920	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HER31_RS09925	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HER31_RS09950	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HER31_RS09955	ENOG4105C8N	cysteinyl-tRNA synthetase
HER31_RS09960	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HER31_RS09965	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HER31_RS09970	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
HER31_RS09980	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HER31_RS09985	ENOG4105E96	Colicin v production protein
HER31_RS09990	ENOG4108S3P	Sporulation domain protein
HER31_RS09995	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HER31_RS10000	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HER31_RS10005	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HER31_RS10015	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HER31_RS10020	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
HER31_RS10025	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HER31_RS10055	ENOG4109015	Biopolymer transport protein exbD tolR
HER31_RS10090	ENOG4105ZIT	Porin Gram-negative type
HER31_RS10095	ENOG4105CQ2	DNA polymerase
HER31_RS10100	ENOG4105DVT	helicase
HER31_RS10105	ENOG4105EJ9	Membrane
HER31_RS10120	ENOG4105DGU	Histone deacetylase
HER31_RS10145	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HER31_RS10155	ENOG4105CNW	domain protein
HER31_RS10160	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
HER31_RS10170	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HER31_RS10180	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
HER31_RS10200	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HER31_RS10205	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HER31_RS10210	ENOG4108DG9	Smr protein MutS2
HER31_RS10215	ENOG4108BY2	phosphohistidine phosphatase
HER31_RS10220	ENOG4107QXK	peptidase
HER31_RS10225	ENOG4105BZU	Histidine kinase
HER31_RS10230	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HER31_RS10235	ENOG4105CHU	acetyl-coa acetyltransferase
HER31_RS10245	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HER31_RS10305	ENOG4105CK7	Sodium proline symporter
HER31_RS10310	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
HER31_RS10320	ENOG4105D78	K07001 NTE family protein
HER31_RS10325	ENOG4105CHH	sulfate transporter
HER31_RS10345	ENOG4105C1J	atp-dependent rna helicase
HER31_RS10355	ENOG4105E1Q	flagellar hook-associated protein
HER31_RS10360	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HER31_RS10365	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HER31_RS10375	ENOG4105CGA	flagellar basal-body rod protein FlgG
HER31_RS10380	ENOG4105CGA	flagellar basal-body rod protein FlgG
HER31_RS10385	ENOG4105BZE	flagellar hook protein, FlgE
HER31_RS10390	ENOG410822I	Flagellar hook capping protein
HER31_RS10395	ENOG4108ZC9	flagellar basal-body rod protein flgc
HER31_RS10400	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HER31_RS10405	ENOG4105BZU	Histidine kinase
HER31_RS10480	ENOG4105DVF	Cytosine-specific methyltransferase
HER31_RS10490	ENOG4108QBF	Transcriptional regulator
HER31_RS10495	ENOG4107EFR	Flavocytochrome c
HER31_RS10520	ENOG4105EJC	lysr family transcriptional regulator
HER31_RS10530	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HER31_RS10570	ENOG4105KWG	Pfam:DUF1696
HER31_RS10585	ENOG4105CA0	peroxidase
HER31_RS10590	ENOG4105C1G	acyl-Coa dehydrogenase
HER31_RS10595	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HER31_RS10600	ENOG4105CHU	acetyl-coa acetyltransferase
HER31_RS10605	ENOG4108ZX5	transcriptional regulator
HER31_RS10610	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HER31_RS10640	ENOG4105CEY	Amp-dependent synthetase and ligase
HER31_RS10645	ENOG4105D05	Receptor
HER31_RS10650	ENOG4108JJB	ABC transporter
HER31_RS10675	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HER31_RS10685	ENOG4107RKG	DJ-1/PfpI family
HER31_RS10695	ENOG4105C5W	Aldolase
HER31_RS10705	ENOG4105CMR	udp-glucose 4-epimerase
HER31_RS10725	ENOG4105ESV	Glycosyl transferase, family 4
HER31_RS10735	ENOG4105D5G	Transposase
HER31_RS10765	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HER31_RS10785	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HER31_RS10790	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
HER31_RS10795	ENOG4105D2T	synthase
HER31_RS10810	ENOG4107V1M	polysaccharide export protein
HER31_RS10815	ENOG4105DUX	Transporter
HER31_RS10820	ENOG4108YXG	UPF0502 protein
HER31_RS10825	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HER31_RS10830	ENOG4108UK5	Transposase
HER31_RS10855	ENOG4108V3W	Chemotaxis protein, CheW
HER31_RS10865	ENOG4107QJE	Chromosome Partitioning Protein
HER31_RS10885	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
HER31_RS10890	ENOG4108VYJ	response regulator receiver protein
HER31_RS10895	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HER31_RS10905	ENOG4105FZW	flagellar biosynthesis regulator FlhF
HER31_RS10910	ENOG4105D7B	Flagellar biosynthesis protein flha
HER31_RS10915	ENOG4105D00	flagellar biosynthetic protein flhB
HER31_RS10920	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HER31_RS10925	ENOG4105VS8	Flagellar biosynthetic protein fliq
HER31_RS10930	ENOG4105CN7	Flagellar biosynthetic protein FliP
HER31_RS10935	ENOG4105VTB	flagellar biosynthesis protein fliO
HER31_RS10940	ENOG4105DD5	Flagellar motor switch protein
HER31_RS10945	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HER31_RS10965	ENOG4108JIR	Flagellum-specific ATP synthase
HER31_RS10975	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HER31_RS10980	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HER31_RS10985	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
HER31_RS10995	ENOG4105BZU	Histidine kinase
HER31_RS11005	ENOG4105MQ3	flagellar protein FliS
HER31_RS11015	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
HER31_RS11025	ENOG4105I03	Flagellin
HER31_RS11030	ENOG4107104	thymidine kinase
HER31_RS11035	ENOG4107S6Z	Na H antiporter
HER31_RS11045	ENOG4105C10	Electron transfer flavoprotein
HER31_RS11050	ENOG4105BZJ	Electron transfer flavoprotein
HER31_RS11055	ENOG4108YX2	DNA-binding protein
HER31_RS11060	ENOG4105CI2	imidazolone-5-propionate hydrolase
HER31_RS11075	ENOG4108R96	Methyltransferase, YaeB family
HER31_RS11080	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HER31_RS11085	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HER31_RS11100	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HER31_RS11105	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HER31_RS11110	ENOG4105C0B	DNA polymerase III (alpha subunit)
HER31_RS11115	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HER31_RS11120	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HER31_RS11125	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HER31_RS11135	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HER31_RS11145	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HER31_RS11150	ENOG4105DZP	Membrane-associated zinc metalloprotease
HER31_RS11155	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HER31_RS11160	ENOG4105KNE	Phosphatidate cytidylyltransferase
HER31_RS11165	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HER31_RS11170	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HER31_RS11175	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HER31_RS11180	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HER31_RS11190	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HER31_RS11195	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HER31_RS11200	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HER31_RS11205	ENOG4105CSU	acyl-Coa dehydrogenase
HER31_RS11210	ENOG4105CI1	PTS System
HER31_RS11215	ENOG4105QDK	Flavodoxin
HER31_RS11220	ENOG4105DR9	pseudouridine synthase
HER31_RS11250	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
HER31_RS11255	ENOG4105C26	Dehydrogenase
HER31_RS11260	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
HER31_RS11275	ENOG4105CFP	Peptidase U32
HER31_RS11280	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HER31_RS11305	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HER31_RS11310	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HER31_RS11315	ENOG4105C7N	Xanthine uracil vitamin C permease
HER31_RS11320	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HER31_RS11325	ENOG4105CIN	aminoacyl-histidine dipeptidase
HER31_RS11330	ENOG4105CKW	Inner membrane protein yedI
HER31_RS11340	ENOG4105CHR	reductase
HER31_RS11345	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HER31_RS11350	ENOG4105E39	Enoyl-CoA hydratase
HER31_RS11355	ENOG4105C1G	acyl-Coa dehydrogenase
HER31_RS11360	ENOG4105C26	Dehydrogenase
HER31_RS11365	ENOG4105CHU	acetyl-coa acetyltransferase
HER31_RS11370	ENOG4105CVG	Homoserine O-transsuccinylase
HER31_RS11380	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HER31_RS11390	ENOG4105DP0	ferredoxin-NADP reductase
HER31_RS11395	ENOG4107QJT	sodium dicarboxylate symporter
HER31_RS11405	ENOG4105HDD	phospholipase
HER31_RS11415	ENOG4105CRK	lysyL-tRNA synthetase
HER31_RS11425	ENOG4107S6Z	Na H antiporter
HER31_RS11430	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HER31_RS11460	ENOG4106MAR	Phosphate-selective porin O and P
HER31_RS11480	ENOG4105T95	Thiol disulfide interChange protein
HER31_RS11485	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HER31_RS11490	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HER31_RS11495	ENOG4105BZS	acriflavin resistance protein
HER31_RS11505	ENOG4105C87	Aminotransferase class I and II
HER31_RS11510	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HER31_RS11515	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
HER31_RS11520	ENOG4105C1J	atp-dependent rna helicase
HER31_RS11535	ENOG4105D2N	Aldolase
HER31_RS11540	ENOG4105BZA	Phosphoglycerate kinase
HER31_RS11545	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HER31_RS11550	ENOG4105I08	Pseudouridine synthase
HER31_RS11560	ENOG4105N14	lysine exporter protein LysE YggA
HER31_RS11565	ENOG4105MDZ	Transcriptional activator rfaH
HER31_RS11570	ENOG4105CIY	formyltetrahydrofolate deformylase
HER31_RS11580	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HER31_RS11590	ENOG4105C1J	atp-dependent rna helicase
HER31_RS11605	ENOG4108MR7	Arylsulfotransferase
HER31_RS11615	ENOG4108N92	Thiol disulfide Interchange Protein
HER31_RS11620	ENOG4108PSN	Required for disulfide bond formation in some proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT (By similarity)
HER31_RS11660	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HER31_RS11680	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HER31_RS11690	ENOG4107WI4	Aldose-1-epimerase
HER31_RS11705	ENOG4107RUZ	Sss sodium solute transporter superfamily
HER31_RS11710	ENOG4105ETE	Transcriptional regulator (LacI family
HER31_RS11715	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HER31_RS11720	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HER31_RS11725	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
HER31_RS11730	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HER31_RS11735	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HER31_RS11740	ENOG4105C3F	Signal peptidase i
HER31_RS11745	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HER31_RS11755	ENOG4105VQK	sigma E regulatory protein, MucB RseB
HER31_RS11765	ENOG4105EMN	RNA polymerase sigma factor
HER31_RS11770	ENOG4108IYU	L-aspartate oxidase
HER31_RS11775	ENOG4105Y75	tpr repeat protein
HER31_RS11780	ENOG4105C2C	drug resistance transporter, Bcr CflA
HER31_RS11785	ENOG41063Z6	transcriptional regulator, lysR family
HER31_RS11800	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HER31_RS11805	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HER31_RS11810	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
HER31_RS11815	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HER31_RS11820	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
HER31_RS11825	ENOG4108Q35	Adenylate
HER31_RS11860	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HER31_RS11885	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HER31_RS11890	ENOG4105DVI	reductase, NrfD
HER31_RS11895	ENOG4106XZB	Cytochrome C3
HER31_RS11910	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
HER31_RS11915	ENOG4105QNF	Outer membrane lipoprotein
HER31_RS11935	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
HER31_RS11950	ENOG41090ED	Protein with unknown function (DUF469)
HER31_RS12000	ENOG4105D98	threonine synthase
HER31_RS12005	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HER31_RS12015	ENOG4106FVC	RNA methyltransferase
HER31_RS12020	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
HER31_RS12025	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HER31_RS12070	ENOG4107QJE	Chromosome Partitioning Protein
HER31_RS12080	ENOG4108ZAI	phosphatidylglycerophosphatase a
HER31_RS12085	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HER31_RS12090	ENOG4107YIM	Involved in the transcription termination process (By similarity)
HER31_RS12095	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HER31_RS12110	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HER31_RS12115	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HER31_RS12120	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HER31_RS12125	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
HER31_RS12130	ENOG4107EFR	Flavocytochrome c
HER31_RS12145	ENOG4105C5H	ABC transporter
HER31_RS12165	ENOG4107PAI	alpha helical protein
HER31_RS12170	ENOG4105C8T	Leucyl-tRNA synthetase
HER31_RS12175	ENOG4108U2H	Rare lipoprotein B
HER31_RS12185	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HER31_RS12190	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HER31_RS12195	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HER31_RS12200	ENOG4105CJN	penicillin-binding protein
HER31_RS12205	ENOG4105CNI	cell division protein FtsW
HER31_RS12210	ENOG4105CVE	Lytic murein transglycosylase
HER31_RS12215	ENOG4105K6T	rare lipoprotein A
HER31_RS12220	ENOG4105DZ1	carboxypeptidase
HER31_RS12225	ENOG4108Z43	UPF0250 protein
HER31_RS12230	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HER31_RS12235	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HER31_RS12240	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HER31_RS12255	ENOG4105BZU	Histidine kinase
HER31_RS12260	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HER31_RS12285	ENOG4108JUA	Transcriptional regulator
HER31_RS12300	ENOG4107EFR	Flavocytochrome c
HER31_RS12310	ENOG4105DVI	reductase, NrfD
HER31_RS12315	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HER31_RS12320	ENOG4108J2R	molybdopterin oxidoreductase
HER31_RS12325	ENOG4106AFQ	Histidine kinase
HER31_RS12330	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HER31_RS12340	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HER31_RS12345	ENOG4105HEI	LysR family (Transcriptional regulator
HER31_RS12355	ENOG4105DWK	Membrane
HER31_RS12360	ENOG4107XM3	UPF0442 protein
HER31_RS12370	ENOG4105DR5	peptidase
HER31_RS12375	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HER31_RS12390	ENOG4105C8P	)-transporter
HER31_RS12395	ENOG4105DUM	transcriptional regulator, lysR family
HER31_RS12400	ENOG4107EFR	Flavocytochrome c
HER31_RS12410	ENOG4108I6A	alcohol dehydrogenase
HER31_RS12425	ENOG4106855	Competence protein
HER31_RS12430	ENOG4105CIS	alcohol dehydrogenase
HER31_RS12435	ENOG4105HEI	LysR family (Transcriptional regulator
HER31_RS12465	ENOG4105CH6	catalase
HER31_RS12480	ENOG4105BZU	Histidine kinase
HER31_RS12490	ENOG4105JQN	Transcriptional regulator
HER31_RS12495	ENOG4105ZXK	Dehydrogenase
HER31_RS12500	ENOG4105G63	Type III effector Hrp-dependent
HER31_RS12510	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
HER31_RS12515	ENOG4105C6Z	Gluconate
HER31_RS12540	ENOG4108MR7	Arylsulfotransferase
HER31_RS12560	ENOG4108RCM	Nitroreductase
HER31_RS12585	ENOG4108MR7	Arylsulfotransferase
HER31_RS12590	ENOG4108PSN	Required for disulfide bond formation in some proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT (By similarity)
HER31_RS12595	ENOG4108N92	Thiol disulfide Interchange Protein
HER31_RS12610	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HER31_RS12615	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HER31_RS12620	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HER31_RS12625	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HER31_RS12630	ENOG4105D0A	hydroxylase
HER31_RS12635	ENOG4107RAQ	aminopeptidase
HER31_RS12655	ENOG4105BZU	Histidine kinase
HER31_RS12665	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HER31_RS12675	ENOG4105PC1	Conserved Protein
HER31_RS12680	ENOG4105BZ4	penicillin-binding protein
HER31_RS12685	ENOG4105CQ7	ATP-dependent helicase
HER31_RS12700	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HER31_RS12705	ENOG4105PW4	Sugar fermentation stimulation protein homolog
HER31_RS12710	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HER31_RS12715	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HER31_RS12720	ENOG4105DJ0	Poly(A) Polymerase
HER31_RS12725	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HER31_RS12730	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HER31_RS12735	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HER31_RS12740	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HER31_RS12745	ENOG4105BZU	Histidine kinase
HER31_RS12755	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
HER31_RS12765	ENOG4107MMM	Anti-sigma-factor antagonist
HER31_RS12775	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HER31_RS12790	ENOG4105C5H	ABC transporter
HER31_RS12815	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HER31_RS12820	ENOG4108W15	Protein of unknown function (DUF1456)
HER31_RS12830	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HER31_RS12835	ENOG4107QZF	nitrite reductase NADPH large subunit
HER31_RS12840	ENOG4105WZK	nitrite reductase NADPH small subunit
HER31_RS12845	ENOG4106TNF	Periplasmic binding protein
HER31_RS12850	ENOG4105E5Q	amino acid AbC transporter
HER31_RS12855	ENOG4105CDA	abc transporter atp-binding protein
HER31_RS12880	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HER31_RS12920	ENOG4107EFR	Flavocytochrome c
HER31_RS12950	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HER31_RS12955	ENOG4105V2T	cytochrome C
HER31_RS12970	ENOG4105CFP	Peptidase U32
HER31_RS12990	ENOG4108VKG	metal-dependent hydrolase
HER31_RS13000	ENOG4105C09	Bile acid
HER31_RS13005	ENOG4108UPT	UPF0178 protein
HER31_RS13015	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
HER31_RS13035	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HER31_RS13040	ENOG4105D1S	lipid A biosynthesis
HER31_RS13045	ENOG4105HEI	LysR family (Transcriptional regulator
HER31_RS13050	ENOG4105F27	Major Facilitator
HER31_RS13055	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HER31_RS13070	ENOG4105I7R	Adenylate cyclase
HER31_RS13075	ENOG4107IX6	phosphate transport regulator
HER31_RS13080	ENOG4105CJ3	phosphate transporter
HER31_RS13090	ENOG4105C26	Dehydrogenase
HER31_RS13110	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HER31_RS13125	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HER31_RS13130	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HER31_RS13135	ENOG4105VCC	30S ribosomal protein S21
HER31_RS13145	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HER31_RS13150	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HER31_RS13155	ENOG4105E9F	Enoyl-CoA hydratase
HER31_RS13165	ENOG4105BZU	Histidine kinase
HER31_RS13185	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
HER31_RS13190	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
HER31_RS13200	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HER31_RS13205	ENOG4105DKB	L-sorbosone dehydrogenase
HER31_RS13210	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HER31_RS13215	ENOG4105IPS	esterase
HER31_RS13220	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HER31_RS13225	ENOG4108SX3	cytoplasmic protein
HER31_RS13230	ENOG41087AY	ADP-Ribose pyrophosphatase
HER31_RS13235	ENOG4105DFG	type I secretion outer membrane protein
HER31_RS13255	ENOG4105E39	Enoyl-CoA hydratase
HER31_RS13275	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HER31_RS13280	ENOG4108IQE	Amp-dependent synthetase and ligase
HER31_RS13285	ENOG4105C8V	SAICAR synthetase
HER31_RS13300	ENOG4108JQ7	(ABC) transporter
HER31_RS13305	ENOG4105C3U	ABC transporter
HER31_RS13310	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HER31_RS13315	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HER31_RS13320	ENOG4107QSI	ABC, transporter
HER31_RS13325	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
HER31_RS13330	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HER31_RS13335	ENOG4105CDU	Replicative dna helicase
HER31_RS13360	ENOG4107SXA	Phosphorylase
HER31_RS13370	ENOG4105EFX	secretion protein, HlyD family
HER31_RS13375	ENOG4105KK7	inner membrane protein YiaW
HER31_RS13385	ENOG4105EJQ	L-serine dehydratase
HER31_RS13390	ENOG4105C44	Serine transporter
HER31_RS13395	ENOG4105HF0	Membrane
HER31_RS13400	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HER31_RS13405	ENOG4107SQI	penicillin amidase
HER31_RS13410	ENOG4105C9B	Cysteine desulfurase
HER31_RS13415	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HER31_RS13420	ENOG4105CUZ	uba thif-type nad fad binding protein
HER31_RS13435	ENOG4105WD1	Membrane
HER31_RS13440	ENOG4105BZU	Histidine kinase
HER31_RS13445	ENOG4105CGH	5'-nucleotidase
HER31_RS13455	ENOG4108IAB	Phoh family
HER31_RS13460	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
HER31_RS13465	ENOG4105CJW	magnesium transporter
HER31_RS13475	ENOG4105C5I	Dehydrogenase
HER31_RS13485	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
HER31_RS13490	ENOG4108S0S	Nucleotidyl transferase
HER31_RS13495	ENOG4105EHM	Aminoglycoside phosphotransferase
HER31_RS13500	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HER31_RS13505	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HER31_RS13510	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HER31_RS13520	ENOG4105NWN	ApaG protein
HER31_RS13530	ENOG4108NVR	Methyl-accepting chemotaxis
HER31_RS13540	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HER31_RS13545	ENOG4105K46	50S ribosomal protein l27
HER31_RS13550	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HER31_RS13555	ENOG4105EAH	synthase
HER31_RS13575	ENOG4105C8Y	Acetylornithine aminotransferase
HER31_RS13580	ENOG4105F4X	arginine
HER31_RS13585	ENOG4105C26	Dehydrogenase
HER31_RS13595	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
HER31_RS13600	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
HER31_RS13610	ENOG4105DNZ	Alpha Beta Hydrolase
HER31_RS13630	ENOG4105C5H	ABC transporter
HER31_RS13635	ENOG4105VKU	nucleicacid-binding protein
HER31_RS13650	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HER31_RS13655	ENOG4105VRX	Protein slyX homolog
HER31_RS13665	ENOG4105WH1	Two component transcriptional regulator luxr family
HER31_RS13670	ENOG4105BZU	Histidine kinase
HER31_RS13675	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
HER31_RS13680	ENOG4108YZA	Nitrogen regulatory protein pii
HER31_RS13690	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HER31_RS13695	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
HER31_RS13700	ENOG4105EZR	dyp-type peroxidase family protein
HER31_RS13705	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HER31_RS13715	ENOG4107QKW	extracellular solute-binding protein family 1
HER31_RS13720	ENOG4105C10	Electron transfer flavoprotein
HER31_RS13725	ENOG4105BZJ	Electron transfer flavoprotein
HER31_RS13790	ENOG4105KB2	stringent starvation protein b
HER31_RS13795	ENOG4107MKT	Stringent starvation protein a
HER31_RS13800	ENOG4105EIX	cytochrome c1
HER31_RS13805	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HER31_RS13810	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HER31_RS13815	ENOG4108UJD	30S ribosomal protein S9
HER31_RS13820	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HER31_RS13825	ENOG4105D6Z	AFG1 family ATPase
HER31_RS13835	ENOG4105C0H	protease
HER31_RS13845	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HER31_RS13850	ENOG4105VFK	BolA family
HER31_RS13860	ENOG4105E3I	toluene tolerance
HER31_RS13865	ENOG4107PE3	Mammalian cell entry related domain protein
HER31_RS13870	ENOG4105CY3	ABC transporter, permease
HER31_RS13875	ENOG4105DHJ	ABC, transporter
HER31_RS13885	ENOG4105C2X	Arabinose 5-phosphate isomerase
HER31_RS13890	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
HER31_RS13900	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
HER31_RS13905	ENOG4108IUZ	ABC transporter
HER31_RS13910	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HER31_RS13915	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
HER31_RS13920	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HER31_RS13930	ENOG41080Z8	PHOSPHOCARRIER protein
HER31_RS13940	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HER31_RS13950	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HER31_RS13955	ENOG4105N42	UPF0307 protein
HER31_RS13970	ENOG4107KET	secretion protein, HlyD family
HER31_RS13980	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HER31_RS13995	ENOG4105C03	ribonuclease
HER31_RS14005	ENOG4105VQ7	Rod shape-determining protein MreD
HER31_RS14010	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HER31_RS14050	ENOG4108VAU	general secretion pathway protein G
HER31_RS14060	ENOG4105D7Q	type ii secretion system
HER31_RS14065	ENOG4107QHF	type ii secretion system protein e
HER31_RS14105	ENOG41062P1	Diguanylate cyclase phosphodiesterase
HER31_RS14155	ENOG4105DIA	mandelate racemase muconate lactonizing
HER31_RS14160	ENOG4105C94	Transporter
HER31_RS14185	ENOG4107XMK	single-stranded DNA-binding protein
HER31_RS14195	ENOG4107RDB	Major Facilitator
HER31_RS14200	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HER31_RS14210	ENOG4107EFR	Flavocytochrome c
HER31_RS14225	ENOG4107RZC	phospholipase d
HER31_RS14230	ENOG4105C9B	Cysteine desulfurase
HER31_RS14245	ENOG4108NVR	Methyl-accepting chemotaxis
HER31_RS14250	ENOG4105SYT	Methylenetetrahydrofolate reductase
HER31_RS14255	ENOG4105CFH	Aspartokinase
HER31_RS14260	ENOG4105C28	cystathionine
HER31_RS14265	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
HER31_RS14280	ENOG4108MR7	Arylsulfotransferase
HER31_RS14285	ENOG4105C6K	Malic enzyme
HER31_RS14290	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HER31_RS14295	ENOG4105VFB	Binds the 23S rRNA (By similarity)
HER31_RS14300	ENOG4105C25	Primosomal protein n'
HER31_RS14305	ENOG4105C75	arginyL-tRNA synthetase
HER31_RS14330	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HER31_RS14335	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HER31_RS14350	ENOG4105CGD	Nad-dependent epimerase dehydratase
HER31_RS14370	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HER31_RS14385	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HER31_RS14400	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HER31_RS14405	ENOG410887T	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HER31_RS14410	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HER31_RS14420	ENOG4105F8V	Hydrolase, tatD family
HER31_RS14425	ENOG4105D52	delta-aminolevulinic acid dehydratase
HER31_RS14435	ENOG4106KPZ	rard protein
HER31_RS14440	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
HER31_RS14460	ENOG4105C1J	atp-dependent rna helicase
HER31_RS14470	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HER31_RS14485	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HER31_RS14490	ENOG4107QK7	reductase
HER31_RS14500	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HER31_RS14510	ENOG4105QAX	Iron-sulfur
HER31_RS14515	ENOG4108IEG	Formate dehydrogenase Alpha subunit
HER31_RS14555	ENOG4105BZU	Histidine kinase
HER31_RS14560	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HER31_RS14575	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HER31_RS14580	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HER31_RS14585	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HER31_RS14590	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HER31_RS14600	ENOG4108JJA	ABC, transporter
HER31_RS14615	ENOG4105CDV	Ompa motb domain protein
HER31_RS14640	ENOG4105C4R	Atp-dependent dna helicase
HER31_RS14645	ENOG4105W0Z	cytoplasmic protein
HER31_RS14650	ENOG4105C94	Transporter
HER31_RS14655	ENOG4105C94	Transporter
HER31_RS14670	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
HER31_RS14675	ENOG4105E0C	molybdate abc transporter
HER31_RS14680	ENOG4108NEM	leader-binding protein dmsD
HER31_RS14685	ENOG4105QAX	Iron-sulfur
HER31_RS14690	ENOG4107QY8	reductase
HER31_RS14705	ENOG4105QAX	Iron-sulfur
HER31_RS14710	ENOG4107QY8	reductase
HER31_RS14730	ENOG4108MR7	Arylsulfotransferase
HER31_RS14745	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HER31_RS14750	ENOG4105C5R	Aminotransferase
HER31_RS14770	ENOG4107EFR	Flavocytochrome c
HER31_RS14780	ENOG4105BZS	acriflavin resistance protein
HER31_RS14795	ENOG4105C7B	Threonine dehydratase
HER31_RS14800	ENOG4105C01	Dihydroxy-acid dehydratase
HER31_RS14805	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HER31_RS14820	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HER31_RS14825	ENOG4105C0P	Mg chelatase subunit ChlI
HER31_RS14910	ENOG4105C0P	Mg chelatase subunit ChlI
HER31_RS14920	ENOG4106HNH	Acyl-transferase
HER31_RS14925	ENOG4106HNH	Acyl-transferase
HER31_RS14930	ENOG4108PVQ	transcriptional regulator
HER31_RS14935	ENOG4105CR4	methylisocitrate lyase
HER31_RS14940	ENOG4105BZN	citrate synthase
HER31_RS14945	ENOG4108I0Z	Aconitate hydratase
HER31_RS14950	ENOG4105C7F	AcnD-accessory protein PrpF
HER31_RS14955	ENOG4106855	Competence protein
HER31_RS14980	ENOG4108Z33	Thiol disulfide Interchange Protein
HER31_RS14985	ENOG4105E27	serine threonine protein kinase
HER31_RS14995	ENOG4105CNG	UPF0061 protein
HER31_RS15005	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
HER31_RS15010	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HER31_RS15015	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HER31_RS15020	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HER31_RS15025	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HER31_RS15035	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HER31_RS15040	ENOG4108VUY	thioesterase Superfamily protein
HER31_RS15045	ENOG4105FR1	rard protein
HER31_RS15055	ENOG4105ECF	c-methyltransferase
HER31_RS15060	ENOG41076E6	Uroporphyrinogen-III Synthase
HER31_RS15065	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HER31_RS15070	ENOG4107T0K	Adenylate cyclase
HER31_RS15075	ENOG4105XQ6	frataxin-like protein
HER31_RS15085	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HER31_RS15100	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HER31_RS15105	ENOG4105CJ2	(LipO)protein
HER31_RS15115	ENOG4105BZU	Histidine kinase
HER31_RS15125	ENOG4105BZU	Histidine kinase
HER31_RS15130	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
HER31_RS15135	ENOG4105C4R	Atp-dependent dna helicase
HER31_RS15150	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HER31_RS15155	ENOG4105E0F	Histidine kinase
HER31_RS15180	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HER31_RS15185	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
HER31_RS15200	ENOG4105KXX	peptidase s58 dmpa
HER31_RS15215	ENOG4108MR7	Arylsulfotransferase
HER31_RS15225	ENOG4108N92	Thiol disulfide Interchange Protein
HER31_RS15230	ENOG4105G2Y	Transcriptional regulator
HER31_RS15250	ENOG4108MR7	Arylsulfotransferase
HER31_RS15265	ENOG4108MR7	Arylsulfotransferase
HER31_RS15270	ENOG4105CIC	tryptophan-specific transport protein
HER31_RS15280	ENOG4108PSN	Required for disulfide bond formation in some proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT (By similarity)
HER31_RS15285	ENOG4108N92	Thiol disulfide Interchange Protein
HER31_RS15290	ENOG4108MR7	Arylsulfotransferase
HER31_RS15300	ENOG4108PSN	Required for disulfide bond formation in some proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT (By similarity)
HER31_RS15305	ENOG4108N92	Thiol disulfide Interchange Protein
HER31_RS15310	ENOG4105C94	Transporter
HER31_RS15315	ENOG4105ECR	NmrA family
HER31_RS15320	ENOG4105CDV	Ompa motb domain protein
HER31_RS15325	ENOG4108PSN	Required for disulfide bond formation in some proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT (By similarity)
HER31_RS15330	ENOG4108N92	Thiol disulfide Interchange Protein
HER31_RS15340	ENOG4108MR7	Arylsulfotransferase
HER31_RS15345	ENOG4107YNJ	LysR family Transcriptional regulator
HER31_RS15375	ENOG4105CT4	transporter
HER31_RS15380	ENOG41090A1	ferritin
HER31_RS15400	ENOG4105DGW	oligopeptidase A
HER31_RS15410	ENOG4105DC8	reductase
HER31_RS15425	ENOG4107SFQ	iron-sulfur binding
HER31_RS15445	ENOG4105R8C	Transcriptional regulator
HER31_RS15450	ENOG4107EFR	Flavocytochrome c
HER31_RS15475	ENOG4105EW9	transcriptional regulator AsnC family
HER31_RS15485	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HER31_RS15490	ENOG4105E4F	Isochorismate synthase
HER31_RS15495	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
HER31_RS15500	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
HER31_RS15515	ENOG4105CEY	Amp-dependent synthetase and ligase
HER31_RS15550	ENOG4108Z0R	Transferase
HER31_RS15555	ENOG4105SG3	Protein of unknown function (DUF1488)
HER31_RS15560	ENOG4105E2X	shikimate dehydrogenase
HER31_RS15565	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HER31_RS15570	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HER31_RS15575	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HER31_RS15580	ENOG4108WI1	Dna topoisomerase
HER31_RS15585	ENOG4108RPN	Protein smg homolog
HER31_RS15590	ENOG4105C79	DNA protecting protein DprA
HER31_RS15600	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HER31_RS15605	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HER31_RS15610	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HER31_RS15615	ENOG4105C1A	potassium transporter peripheral membrane
HER31_RS15630	ENOG41080HT	Transcriptional regulator, arsr family
HER31_RS15635	ENOG4108RR8	protoporphyrinogen oxidase
HER31_RS15640	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HER31_RS15645	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HER31_RS15655	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HER31_RS15665	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HER31_RS15670	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HER31_RS15675	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HER31_RS15680	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
HER31_RS15685	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HER31_RS15690	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HER31_RS15695	ENOG4105K8R	UPF0145 protein
HER31_RS15700	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HER31_RS15710	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HER31_RS15715	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HER31_RS15720	ENOG4105VG0	50S ribosomal protein l34
HER31_RS15725	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HER31_RS15735	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HER31_RS15740	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HER31_RS15745	ENOG4105QTB	Flavodoxin
HER31_RS15750	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HER31_RS15755	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HER31_RS15760	ENOG4107QJE	Chromosome Partitioning Protein
HER31_RS15765	ENOG4105FA0	parb-like partition protein
HER31_RS15775	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
HER31_RS15785	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HER31_RS15790	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HER31_RS15795	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HER31_RS15800	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HER31_RS15805	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HER31_RS15820	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HER31_RS15830	ENOG410804X	Transcriptional regulator
HER31_RS15835	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HER31_RS15885	ENOG4108IQE	Amp-dependent synthetase and ligase
HER31_RS15895	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
HER31_RS15900	ENOG4105CUY	Mechanosensitive ion channel
HER31_RS15910	ENOG4105CPI	Metal Dependent Phosphohydrolase
HER31_RS15915	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
HER31_RS15925	ENOG4106H78	methyltransferase
HER31_RS15930	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HER31_RS15935	ENOG4105CAK	Cell division ATP-binding protein ftsE
HER31_RS15940	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HER31_RS15945	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HER31_RS15950	ENOG4105KRS	Proteinase inhibitor
HER31_RS15965	ENOG4107QY8	reductase
HER31_RS15970	ENOG4105QAX	Iron-sulfur
HER31_RS15975	ENOG4108NEM	leader-binding protein dmsD
HER31_RS15980	ENOG4105PXI	polysaccharide deacetylase
HER31_RS15985	ENOG4105CN1	protease
HER31_RS15990	ENOG41063SB	peptidase
HER31_RS15995	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HER31_RS16000	ENOG4107YZP	Rhodanese domain protein
HER31_RS16005	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HER31_RS16010	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HER31_RS16015	ENOG4105CBX	hi0933 family
HER31_RS16025	ENOG4105DUM	transcriptional regulator, lysR family
HER31_RS16040	ENOG4105TMB	Formate nitrite transporter
HER31_RS16045	ENOG4105BZU	Histidine kinase
HER31_RS16050	ENOG4108EUD	Lysophospholipase
HER31_RS16065	ENOG4105D4P	Coproporphyrinogen iii oxidase
HER31_RS16075	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
HER31_RS16085	ENOG4106RE7	Cytochrome
HER31_RS16090	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HER31_RS16095	ENOG4105C2M	dna polymerase I
HER31_RS16100	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
HER31_RS16110	ENOG4105EST	Metal Dependent Phosphohydrolase
HER31_RS16115	ENOG4105EX9	Membrane
HER31_RS16120	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HER31_RS16125	ENOG4105D06	uba thif-type nad fad binding protein
HER31_RS16130	ENOG4105Y3U	Transglycosylase-associated protein
HER31_RS16135	ENOG4105KNA	-acetyltransferase
HER31_RS16140	ENOG4108W1A	pseudouridine synthase
HER31_RS16145	ENOG4108ZAF	Molybdopterin
HER31_RS16150	ENOG4105M00	molybdopterin converting factor, subunit 1
HER31_RS16155	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HER31_RS16160	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HER31_RS16165	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HER31_RS16170	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HER31_RS16175	ENOG4105G2Y	Transcriptional regulator
HER31_RS16180	ENOG4108MR7	Arylsulfotransferase
HER31_RS16185	ENOG4108PSN	Required for disulfide bond formation in some proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT (By similarity)
HER31_RS16190	ENOG4108N92	Thiol disulfide Interchange Protein
HER31_RS16195	ENOG4105BZU	Histidine kinase
HER31_RS16200	ENOG4108TFM	Kinase, PfkB family
HER31_RS16220	ENOG4105QAX	Iron-sulfur
HER31_RS16225	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HER31_RS16235	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HER31_RS16240	ENOG4105CUX	Signal transduction histidine kinase
HER31_RS16250	ENOG4105C5F	glutamine synthetase
HER31_RS16255	ENOG4105CI3	gtp-binding protein typa
HER31_RS16260	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HER31_RS16265	ENOG4105FE9	pseudouridine synthase
HER31_RS16280	ENOG4107S2Z	UPF0761 membrane protein
HER31_RS16285	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HER31_RS16295	ENOG4105CB5	ATP-dependent DNA helicase recG
HER31_RS16300	ENOG4108IQE	Amp-dependent synthetase and ligase
HER31_RS16305	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
HER31_RS16310	ENOG4105KME	endoribonuclease L-psp
HER31_RS16315	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HER31_RS16320	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HER31_RS16330	ENOG4105CGY	Dna recombination protein
HER31_RS16335	ENOG4105DU0	nucleoside hydrolase
HER31_RS16340	ENOG4105D6J	arsenicaL-resistance protein
HER31_RS16380	ENOG4105DSJ	YicC domain protein
HER31_RS16385	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HER31_RS16390	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HER31_RS16395	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HER31_RS16400	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HER31_RS16410	ENOG4105W5Q	DNA repair protein (RadC
HER31_RS16415	ENOG4105KDC	50s ribosomal protein l28
HER31_RS16425	ENOG4105EXC	Acyl-transferase
HER31_RS16435	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HER31_RS16440	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HER31_RS16450	ENOG4105XA0	heptosyltransferase ii
HER31_RS16460	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HER31_RS16465	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HER31_RS16470	ENOG4106WTF	Glycosyl transferase, family 2
HER31_RS16480	ENOG4108I69	Glycosyl transferases group 1
HER31_RS16485	ENOG4105CPK	Glycosyl transferase (Group 1
HER31_RS16490	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HER31_RS16500	ENOG4105DKP	glycosyl transferase, family 9
HER31_RS16505	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
HER31_RS16510	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HER31_RS16525	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HER31_RS16530	ENOG4105CPQ	Dehydrogenase
HER31_RS16535	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HER31_RS16540	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
HER31_RS16565	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
HER31_RS16570	ENOG4108IJF	Heavy metal efflux pump, CzcA
HER31_RS16575	ENOG4105CYM	Glutathione S-transferase
HER31_RS16585	ENOG4107QX8	SPFH domain, Band 7 family protein
HER31_RS16595	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
HER31_RS16630	ENOG4106IUH	DTW domain containing protein
HER31_RS16635	ENOG4105E55	glycerol-3-phosphate acyltransferase
HER31_RS16640	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HER31_RS16650	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
HER31_RS16655	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HER31_RS16660	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
HER31_RS16665	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
HER31_RS16685	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
HER31_RS16690	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HER31_RS16700	ENOG4107BJW	polysaccharide deacetylase
HER31_RS16705	ENOG4107R73	Mate efflux family protein
HER31_RS16710	ENOG4105BZU	Histidine kinase
HER31_RS16715	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
HER31_RS16720	ENOG4105MJ2	Competence protein
HER31_RS16725	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HER31_RS16735	ENOG4105BZM	domain protein
HER31_RS16740	ENOG4108RRZ	Transcription elongation factor GreB
HER31_RS16750	ENOG4105E0F	Histidine kinase
HER31_RS16755	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HER31_RS16760	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HER31_RS16765	ENOG4105VEJ	Heat shock protein
HER31_RS16770	ENOG4108XKW	General secretion pathway protein C
HER31_RS16780	ENOG4107QHF	type ii secretion system protein e
HER31_RS16785	ENOG4105D7Q	type ii secretion system
HER31_RS16790	ENOG4108VAU	general secretion pathway protein G
HER31_RS16820	ENOG4105U1E	general secretion pathway protein M
HER31_RS16825	ENOG4105PIC	general secretion pathway protein N
HER31_RS16830	ENOG4107RK2	ADP-ribose diphosphatase NudE
HER31_RS16835	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HER31_RS16840	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
HER31_RS16850	ENOG4105EJ2	Transcriptional regulator
HER31_RS16865	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
HER31_RS16895	ENOG4105D4A	Cell wall formation (By similarity)
HER31_RS16900	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HER31_RS16905	ENOG4105CS9	pantothenic acid kinase
HER31_RS16930	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HER31_RS16935	ENOG4105PM1	preprotein translocase subunit SecE
HER31_RS16940	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HER31_RS16945	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HER31_RS16950	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HER31_RS16955	ENOG4108VZM	50s ribosomal protein L10
HER31_RS16960	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HER31_RS16965	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HER31_RS16970	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HER31_RS16975	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HER31_RS16980	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HER31_RS16990	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HER31_RS16995	ENOG4105FAT	Acyl-transferase
HER31_RS17010	ENOG4105EXC	Acyl-transferase
HER31_RS17040	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
HER31_RS17045	ENOG4107QKV	phosphomannomutase
HER31_RS17050	ENOG4105D3Q	Sugar transferase
HER31_RS17070	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HER31_RS17075	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HER31_RS17080	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HER31_RS17085	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HER31_RS17095	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HER31_RS17100	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HER31_RS17105	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HER31_RS17110	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HER31_RS17115	ENOG41083MP	50s ribosomal protein l29
HER31_RS17120	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HER31_RS17125	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HER31_RS17130	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HER31_RS17135	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HER31_RS17140	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HER31_RS17145	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HER31_RS17155	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HER31_RS17160	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HER31_RS17165	ENOG4105VPB	50S ribosomal protein L30
HER31_RS17170	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HER31_RS17175	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HER31_RS17185	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HER31_RS17190	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HER31_RS17195	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HER31_RS17200	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HER31_RS17205	ENOG4108ZT0	50S ribosomal protein l17
HER31_RS17215	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
HER31_RS17225	ENOG41060IM	Heme exporter protein
HER31_RS17230	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
HER31_RS17235	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
HER31_RS17240	ENOG4105MPD	Cytochrome
HER31_RS17245	ENOG4108DMF	Cytochrome C biogenesis protein
HER31_RS17250	ENOG4105DA4	cytochrome c-type biogenesis protein
HER31_RS17255	ENOG4107QX9	Thiol disulfide interChange protein
HER31_RS17260	ENOG4105KWW	Biogenesis protein
HER31_RS17265	ENOG4107ZT5	Thiol disulfide interchange protein
HER31_RS17300	ENOG4108I62	cina-like protein
HER31_RS17310	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HER31_RS17315	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HER31_RS17320	ENOG4105CAS	nag kinase
HER31_RS17330	ENOG4105CDH	Citrulline--aspartate ligase
HER31_RS17335	ENOG4105CH7	arginosuccinase
HER31_RS17340	ENOG4108JQC	penicillin-binding protein 1A
HER31_RS17345	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HER31_RS17365	ENOG4105E4G	Type IV pilus
HER31_RS17370	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HER31_RS17375	ENOG4105D49	3-dehydroquinate synthase
HER31_RS17385	ENOG4105DFE	Dna adenine methylase
HER31_RS17400	ENOG4105DJV	ribulose-phosphate 3-epimerase
HER31_RS17405	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HER31_RS17410	ENOG4105C31	Tryptophanyl-tRNA synthetase
HER31_RS17415	ENOG4105W4M	Transport-associated protein
HER31_RS17420	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HER31_RS17425	ENOG41082RQ	UPF0102 protein
HER31_RS17430	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
HER31_RS17435	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HER31_RS17450	ENOG4108V6E	Cell division protein mraZ
HER31_RS17455	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HER31_RS17460	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HER31_RS17465	ENOG4105CJN	penicillin-binding protein
HER31_RS17470	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HER31_RS17475	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HER31_RS17480	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HER31_RS17485	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HER31_RS17490	ENOG4105CNI	cell division protein FtsW
HER31_RS17495	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HER31_RS17500	ENOG4105DFU	Cell wall formation (By similarity)
HER31_RS17505	ENOG4105CPF	Cell wall formation (By similarity)
HER31_RS17510	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HER31_RS17515	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HER31_RS17520	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HER31_RS17525	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HER31_RS17535	ENOG4105DR5	peptidase
HER31_RS17540	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HER31_RS17545	ENOG4105M6F	mutator MutT protein
HER31_RS17555	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
HER31_RS17565	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HER31_RS17570	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
HER31_RS17575	ENOG4105D7Q	type ii secretion system
HER31_RS17580	ENOG4107QHF	type ii secretion system protein e
HER31_RS17585	ENOG4105X0D	Fimbrial protein
HER31_RS17590	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HER31_RS17600	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HER31_RS17610	ENOG41073TP	transcriptional regulator
HER31_RS17615	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HER31_RS17620	ENOG4107QSN	dihydrolipoamide acetyltransferase
HER31_RS17625	ENOG4107QN2	dihydrolipoyl dehydrogenase
HER31_RS17630	ENOG4105BZU	Histidine kinase
HER31_RS17635	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
HER31_RS17640	ENOG4107QIJ	Aconitate hydratase 2
HER31_RS17645	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
HER31_RS17650	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HER31_RS17660	ENOG4105DD7	kinase (PfkB family
HER31_RS17665	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
HER31_RS17670	ENOG4108RG0	uracil-dna glycosylase
HER31_RS17675	ENOG4105BZU	Histidine kinase
HER31_RS17680	ENOG4108NRW	Phospholipase, patatin family
HER31_RS17685	ENOG4105CCT	upf0313 protein
HER31_RS17690	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HER31_RS17705	ENOG4105CQ7	ATP-dependent helicase
HER31_RS17735	ENOG4105C12	Phosphoribosylglycinamide synthetase
HER31_RS17740	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HER31_RS17760	ENOG4105DWU	Membrane
HER31_RS17775	ENOG4105C1J	atp-dependent rna helicase
HER31_RS17780	ENOG4108ZG0	Ompa motb domain protein
HER31_RS17795	ENOG4105C8P	)-transporter
HER31_RS17805	ENOG4105CDY	transcriptional regulatory protein
HER31_RS17820	ENOG4105C0D	helicase
HER31_RS17855	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
HER31_RS17860	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HER31_RS17865	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HER31_RS17875	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HER31_RS17880	ENOG4105E33	succinate dehydrogenase
HER31_RS17890	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HER31_RS17895	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HER31_RS17900	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HER31_RS17905	ENOG4108YZN	class I peptide chain release factor
HER31_RS17925	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HER31_RS17930	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HER31_RS17935	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HER31_RS17940	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HER31_RS17945	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HER31_RS17950	ENOG4105VF7	tolerance protein
HER31_RS17955	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
HER31_RS17965	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HER31_RS17970	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HER31_RS17985	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HER31_RS17995	ENOG4105CEP	NADH dehydrogenase
HER31_RS18020	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HER31_RS18025	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HER31_RS18030	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
HER31_RS18055	ENOG4108UQY	Iron-storage protein
HER31_RS18060	ENOG4105W53	bacterioferritin-associated ferredoxin
HER31_RS18065	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HER31_RS18070	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HER31_RS18075	ENOG4105EGS	Mechanosensitive ion channel
HER31_RS18080	ENOG4105DJ4	phosphatidylserine decarboxylase
HER31_RS18085	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HER31_RS18090	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HER31_RS18125	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HER31_RS18130	ENOG4105K8N	protein family UPF0079, ATPase
HER31_RS18135	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HER31_RS18145	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HER31_RS18150	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HER31_RS18155	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HER31_RS18160	ENOG4107QJR	hflk protein
HER31_RS18165	ENOG4105EPW	hflc protein
HER31_RS18175	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HER31_RS18180	ENOG4108UV7	flagellar protein motX
HER31_RS18185	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HER31_RS18190	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HER31_RS18200	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HER31_RS18210	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HER31_RS18215	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HER31_RS18230	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HER31_RS18240	ENOG4105D7T	ABC transporter
HER31_RS18265	ENOG4109015	Biopolymer transport protein exbD tolR
HER31_RS18295	ENOG4105E0A	ABC, transporter
HER31_RS18300	ENOG4105EHG	Permease protein
HER31_RS18310	ENOG4107RNH	Outer membrane receptor FepA
HER31_RS18345	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
HER31_RS18350	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
HER31_RS18355	ENOG4108RCM	Nitroreductase
HER31_RS18365	ENOG4105C5E	polysaccharide biosynthesis protein
HER31_RS18410	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HER31_RS18420	ENOG4108K5H	permease YjgP YjgQ family protein
HER31_RS18425	ENOG4108M8S	permease YjgP YjgQ family protein
HER31_RS18430	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HER31_RS18440	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HER31_RS18475	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HER31_RS18485	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HER31_RS18505	ENOG41090EX	DsrE family
HER31_RS18510	ENOG4108JJB	ABC transporter
HER31_RS18530	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HER31_RS18535	ENOG4105C45	hydrogenase expression formation protein (HypE)
HER31_RS18540	ENOG4105CQS	hydrogenase expression formation protein HypD
HER31_RS18545	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
HER31_RS18550	ENOG4105DGW	oligopeptidase A
HER31_RS18555	ENOG4108PZW	LysR family Transcriptional regulator
HER31_RS18565	ENOG4105CHR	reductase
HER31_RS18585	ENOG4105D78	K07001 NTE family protein
HER31_RS18600	ENOG4105E9F	Enoyl-CoA hydratase
HER31_RS18605	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HER31_RS18610	ENOG4105W8H	transhydrogenase (subunit alpha
HER31_RS18615	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HER31_RS18620	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HER31_RS18625	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HER31_RS18630	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HER31_RS18640	ENOG4105EN6	Membrane
HER31_RS18650	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HER31_RS18655	ENOG4105D6U	Sodium Glutamate Symporter
HER31_RS18680	ENOG4105D9P	serine threonine protein kinase
HER31_RS18685	ENOG4108ZF3	Phosphatase
HER31_RS18700	ENOG4105BZ8	glutamate synthase
HER31_RS18705	ENOG4105CBC	glutamate synthase
HER31_RS18710	ENOG4105N5T	Radical SAM Protein
HER31_RS18735	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)