locus-tag	class	description
FOC70_RS00020	ENOG4108VB1	regulatoR
FOC70_RS00030	ENOG4108URH	decarboxylase
FOC70_RS00050	ENOG4108URH	decarboxylase
FOC70_RS00065	ENOG4108JJB	ABC transporter
FOC70_RS00085	ENOG4105BZ1	(ABC) transporter
FOC70_RS00090	ENOG4105BZ1	(ABC) transporter
FOC70_RS00100	ENOG4105MZU	cell filamentation protein
FOC70_RS00120	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FOC70_RS00125	ENOG410804D	Sensor Signal Transduction Histidine Kinase
FOC70_RS00140	ENOG4108JJB	ABC transporter
FOC70_RS00155	ENOG4105BZ1	(ABC) transporter
FOC70_RS00170	ENOG4105BZ1	(ABC) transporter
FOC70_RS00175	ENOG4105BZ1	(ABC) transporter
FOC70_RS00225	ENOG4108C33	Resolvase
FOC70_RS00235	ENOG4108R6W	Transcriptional regulator, ARAC family
FOC70_RS00240	ENOG4108JJB	ABC transporter
FOC70_RS00255	ENOG4105BZ1	(ABC) transporter
FOC70_RS00260	ENOG4105BZ1	(ABC) transporter
FOC70_RS00310	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
FOC70_RS00315	ENOG4105BZ1	(ABC) transporter
FOC70_RS00330	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
FOC70_RS00365	ENOG4105DWD	nucleoside recognition domain protein
FOC70_RS00375	ENOG4105MPN	Membrane
FOC70_RS00390	ENOG4105DZW	Dipeptidase
FOC70_RS00400	ENOG4108JJB	ABC transporter
FOC70_RS00405	ENOG4108JJB	ABC transporter
FOC70_RS00445	ENOG4105DBI	uridine monophosphokinase
FOC70_RS00450	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
FOC70_RS00455	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
FOC70_RS00470	ENOG4105JFG	SpoIID LytB domain protein
FOC70_RS00475	ENOG4107RA4	Glycosyl transferase (Group 1
FOC70_RS00505	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
FOC70_RS00510	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FOC70_RS00515	ENOG4105CIN	aminoacyl-histidine dipeptidase
FOC70_RS00530	ENOG4105C87	Aminotransferase class I and II
FOC70_RS00535	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
FOC70_RS00550	ENOG4105C94	Transporter
FOC70_RS00575	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
FOC70_RS00580	ENOG4108UJD	30S ribosomal protein S9
FOC70_RS00585	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
FOC70_RS00595	ENOG4105MJ6	selenium-dependent hydroxylase accessory protein YqeC
FOC70_RS00625	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
FOC70_RS00650	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
FOC70_RS00675	ENOG4105CGZ	zinc metallopeptidase
FOC70_RS00685	ENOG4105C7H	Helicase, RecD TraA family
FOC70_RS00690	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
FOC70_RS00715	ENOG4105JFG	SpoIID LytB domain protein
FOC70_RS00720	ENOG4105BZ1	(ABC) transporter
FOC70_RS00735	ENOG4108NEV	two component transcriptional regulator, LytTR family
FOC70_RS00745	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FOC70_RS00795	ENOG4105DZP	Membrane-associated zinc metalloprotease
FOC70_RS00810	ENOG4105N5T	Radical SAM Protein
FOC70_RS00815	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOC70_RS00820	ENOG4108KP7	hydrolase
FOC70_RS00825	ENOG41068XD	UPF0473 protein
FOC70_RS00830	ENOG4105CIN	aminoacyl-histidine dipeptidase
FOC70_RS00840	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FOC70_RS00855	ENOG4105EKX	Restriction modification system DNA (Specificity
FOC70_RS00860	ENOG4105DZR	Type I site-specific deoxyribonuclease
FOC70_RS00885	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
FOC70_RS00895	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
FOC70_RS00910	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
FOC70_RS00925	ENOG4105CSR	polyphosphate kinase 2
FOC70_RS00930	ENOG4105DEN	Luciferase family
FOC70_RS00970	ENOG4105DA5	(ABC) transporter
FOC70_RS01000	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
FOC70_RS01030	ENOG4108Z66	YbaK ebsC protein
FOC70_RS01060	ENOG4108UK2	deaminase
FOC70_RS01085	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
FOC70_RS01110	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
FOC70_RS01125	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FOC70_RS01160	ENOG4108RAC	Rubrerythrin
FOC70_RS01170	ENOG4108KCW	iron-sulfur cluster binding
FOC70_RS01210	ENOG4105C8J	)-transporter
FOC70_RS01220	ENOG4105EZ5	reductase
FOC70_RS01230	ENOG4105EPI	acetyltransferase, (GNAT) family
FOC70_RS01240	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
FOC70_RS01245	ENOG4108RS6	transposase
FOC70_RS01260	ENOG4108IJ2	phosphate acetyltransferase
FOC70_RS01270	ENOG4105C3J	Cysteine desulfurase
FOC70_RS01280	ENOG4105FA0	parb-like partition protein
FOC70_RS01285	ENOG4107QJE	Chromosome Partitioning Protein
FOC70_RS01290	ENOG4105CEV	competence damage-inducible protein
FOC70_RS01295	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
FOC70_RS01300	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
FOC70_RS01305	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
FOC70_RS01310	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
FOC70_RS01315	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FOC70_RS01320	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
FOC70_RS01325	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
FOC70_RS01330	ENOG4105VG0	50S ribosomal protein l34
FOC70_RS01335	ENOG41085FC	arsR family transcriptional regulator
FOC70_RS01350	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
FOC70_RS01360	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FOC70_RS01370	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FOC70_RS01375	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FOC70_RS01380	ENOG4105WN5	stage II sporulation protein
FOC70_RS01395	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
FOC70_RS01400	ENOG4105C4B	ABC transporter, permease
FOC70_RS01405	ENOG4105C9Q	fumarate hydratase class II
FOC70_RS01455	ENOG4105DSE	periplasmic solute binding protein
FOC70_RS01460	ENOG4105FDK	ABC transporter
FOC70_RS01480	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
FOC70_RS01510	ENOG4105DQ6	Transposase
FOC70_RS01535	ENOG4105DPN	Oligoendopeptidase f
FOC70_RS01540	ENOG4108JJB	ABC transporter
FOC70_RS01555	ENOG4108YZ8	Superoxide reductase
FOC70_RS01575	ENOG4106CVF	DNA replication protein
FOC70_RS01600	ENOG4105DA5	(ABC) transporter
FOC70_RS01660	ENOG4105DFS	Conserved Protein
FOC70_RS01695	ENOG4105EKQ	RNA-directed DNA polymerase
FOC70_RS01760	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FOC70_RS01775	ENOG4105EKQ	RNA-directed DNA polymerase
FOC70_RS01790	ENOG4105CJA	serine threonine protein kinase
FOC70_RS01820	ENOG4105BZ1	(ABC) transporter
FOC70_RS01825	ENOG4105MU5	relaxase mobilization nuclease domain protein
FOC70_RS01850	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
FOC70_RS01875	ENOG4108MIW	Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions
FOC70_RS01890	ENOG4108JJB	ABC transporter
FOC70_RS01895	ENOG4105BZ1	(ABC) transporter
FOC70_RS01900	ENOG4105BZ1	(ABC) transporter
FOC70_RS01955	ENOG4105EKQ	RNA-directed DNA polymerase
FOC70_RS01970	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
FOC70_RS01985	ENOG4105C59	p-type ATPase
FOC70_RS02010	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
FOC70_RS02020	ENOG4105DFS	Conserved Protein
FOC70_RS02030	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
FOC70_RS02050	ENOG4105C0P	Mg chelatase subunit ChlI
FOC70_RS02070	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
FOC70_RS02100	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FOC70_RS02105	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
FOC70_RS02125	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
FOC70_RS02145	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
FOC70_RS02150	ENOG4105CDU	Replicative dna helicase
FOC70_RS02170	ENOG4107U9W	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX (By similarity)
FOC70_RS02205	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
FOC70_RS02215	ENOG4105DZ1	carboxypeptidase
FOC70_RS02250	ENOG4105DQ6	Transposase
FOC70_RS02275	ENOG4108Z86	Glutamine amidotransferase
FOC70_RS02290	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
FOC70_RS02315	ENOG4105C8U	phosphate abc transporter
FOC70_RS02325	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FOC70_RS02330	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FOC70_RS02345	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FOC70_RS02350	ENOG4108IUW	ABC transporter
FOC70_RS02375	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
FOC70_RS02395	ENOG4105DER	m42 family
FOC70_RS02405	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FOC70_RS02415	ENOG4105DIK	(ABC) transporter
FOC70_RS02430	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FOC70_RS02435	ENOG4105DQ6	Transposase
FOC70_RS02460	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
FOC70_RS02475	ENOG4105C8N	cysteinyl-tRNA synthetase
FOC70_RS02485	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
FOC70_RS02495	ENOG4105UQX	Mate efflux family protein
FOC70_RS02505	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
FOC70_RS02510	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
FOC70_RS02515	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
FOC70_RS02520	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
FOC70_RS02525	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FOC70_RS02530	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
FOC70_RS02535	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
FOC70_RS02540	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
FOC70_RS02545	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
FOC70_RS02550	ENOG41082SA	50s ribosomal protein l29
FOC70_RS02555	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
FOC70_RS02560	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
FOC70_RS02565	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
FOC70_RS02570	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FOC70_RS02575	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
FOC70_RS02580	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
FOC70_RS02585	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
FOC70_RS02590	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
FOC70_RS02595	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
FOC70_RS02600	ENOG4105VPB	50S ribosomal protein L30
FOC70_RS02605	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
FOC70_RS02615	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
FOC70_RS02630	ENOG41067V7	50S ribosomal protein L36
FOC70_RS02635	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOC70_RS02640	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
FOC70_RS02645	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FOC70_RS02650	ENOG4108ZT0	50S ribosomal protein l17
FOC70_RS02660	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
FOC70_RS02780	ENOG4105DQ6	Transposase
FOC70_RS02795	ENOG4108YYD	acetyltransferase
FOC70_RS02805	ENOG4105MZU	cell filamentation protein
FOC70_RS02835	ENOG4105BZ1	(ABC) transporter
FOC70_RS02840	ENOG4105BZ1	(ABC) transporter
FOC70_RS02845	ENOG4108IUJ	4-alpha-glucanotransferase
FOC70_RS02850	ENOG4105DWF	phosphomethylpyrimidine kinase
FOC70_RS02855	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FOC70_RS02870	ENOG4105CEM	UPF0597 protein
FOC70_RS02875	ENOG4105JHY	Membrane
FOC70_RS02880	ENOG4105CIN	aminoacyl-histidine dipeptidase
FOC70_RS02885	ENOG4105CHM	Aminotransferase
FOC70_RS02890	ENOG4105DZS	Phenylacetate-CoA ligase
FOC70_RS02895	ENOG4105DDK	oxidoreductase, beta subunit
FOC70_RS02900	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
FOC70_RS02910	ENOG4105EJ5	oxidoreductase gamma subunit
FOC70_RS02925	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FOC70_RS02935	ENOG4105CFF	transcriptional regulator
FOC70_RS02945	ENOG4105DSE	periplasmic solute binding protein
FOC70_RS02950	ENOG4105FDK	ABC transporter
FOC70_RS02955	ENOG4105FAV	ABC, transporter
FOC70_RS02980	ENOG4108KCW	iron-sulfur cluster binding
FOC70_RS02985	ENOG4108N5C	SNARE associated Golgi protein-related protein
FOC70_RS02995	ENOG4105CJ1	ABC, transporter
FOC70_RS03010	ENOG4107QQ0	gntp family
FOC70_RS03015	ENOG4105BZW	Glycerate kinase
FOC70_RS03020	ENOG4107VHA	regulatoR
FOC70_RS03025	ENOG4107U9T	Pfam:Ribonuclease_BN
FOC70_RS03030	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
FOC70_RS03040	ENOG4105BZ1	(ABC) transporter
FOC70_RS03050	ENOG4107QHF	type ii secretion system protein e
FOC70_RS03055	ENOG4105D7Q	type ii secretion system
FOC70_RS03070	ENOG4105CGK	Exodeoxyribonuclease III
FOC70_RS03085	ENOG4108N5C	SNARE associated Golgi protein-related protein
FOC70_RS03090	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
FOC70_RS03095	ENOG4105CPF	Cell wall formation (By similarity)
FOC70_RS03110	ENOG4105D7N	magnesium and cobalt transport protein CorA
FOC70_RS03120	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
FOC70_RS03130	ENOG4105DE4	1-phosphofructokinase
FOC70_RS03140	ENOG4108JQ7	(ABC) transporter
FOC70_RS03145	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FOC70_RS03165	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FOC70_RS03170	ENOG4105K7K	Transcriptional regulator
FOC70_RS03180	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
FOC70_RS03190	ENOG4107QYV	phosphohexose isomerase
FOC70_RS03200	ENOG4105D7A	ATP-binding protein
FOC70_RS03205	ENOG4108RS6	transposase
FOC70_RS03225	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FOC70_RS03230	ENOG4105WPN	DNA integration recombination invertion protein
FOC70_RS03245	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FOC70_RS03250	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
FOC70_RS03260	ENOG4108TVT	permease
FOC70_RS03265	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
FOC70_RS03275	ENOG4108RCR	degv family
FOC70_RS03280	ENOG4107QX9	Thiol disulfide interChange protein
FOC70_RS03295	ENOG4105C72	UPF0176 protein
FOC70_RS03325	ENOG4105DZ0	fad dependent oxidoreductase
FOC70_RS03330	ENOG4105DE4	1-phosphofructokinase
FOC70_RS03335	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FOC70_RS03340	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
FOC70_RS03345	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
FOC70_RS03350	ENOG4105C5H	ABC transporter
FOC70_RS03355	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FOC70_RS03380	ENOG4105CFH	Aspartokinase
FOC70_RS03385	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
FOC70_RS03390	ENOG4105D6E	homoserine dehydrogenase
FOC70_RS03395	ENOG4107QID	Threonine synthase
FOC70_RS03400	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
FOC70_RS03415	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
FOC70_RS03455	ENOG41066A3	ATP guanido phosphotransferase
FOC70_RS03465	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
FOC70_RS03480	ENOG4105CCI	Myosin-Cross-Reactive Antigen
FOC70_RS03490	ENOG4105J8Z	peptidase S8 and S53, subtilisin, kexin, sedolisin
FOC70_RS03520	ENOG4108YZG	isomerase
FOC70_RS03525	ENOG4105C2M	dna polymerase I
FOC70_RS03530	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
FOC70_RS03545	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
FOC70_RS03550	ENOG4105D6A	Electron transport complex
FOC70_RS03555	ENOG41080WF	Electron transport complex, RnfABCDGE type, G subunit
FOC70_RS03560	ENOG4105DZB	Electron transport complex
FOC70_RS03565	ENOG4105DGN	Electron transport complex
FOC70_RS03605	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
FOC70_RS03620	ENOG4105W5Q	DNA repair protein (RadC
FOC70_RS03625	ENOG4105DFF	Rod shape-determining protein mreb
FOC70_RS03640	ENOG4105CJN	penicillin-binding protein
FOC70_RS03650	ENOG4107QQB	Ribonuclease E
FOC70_RS03655	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
FOC70_RS03665	ENOG4105K46	50S ribosomal protein l27
FOC70_RS03670	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOC70_RS03680	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
FOC70_RS03685	ENOG4108WF2	Metal Dependent Phosphohydrolase
FOC70_RS03695	ENOG4105KME	endoribonuclease L-psp
FOC70_RS03700	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
FOC70_RS03705	ENOG4105C3G	gtp-binding protein
FOC70_RS03710	ENOG4105DC7	peptidase M24
FOC70_RS03715	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
FOC70_RS03725	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
FOC70_RS03730	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FOC70_RS03750	ENOG4107TT5	NLP P60 protein
FOC70_RS03755	ENOG41069ER	domain protein
FOC70_RS03760	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
FOC70_RS03765	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
FOC70_RS03780	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
FOC70_RS03790	ENOG4105NBU	tryptophan transport protein
FOC70_RS03795	ENOG4108I5U	Uridine phosphorylase
FOC70_RS03805	ENOG4105C2N	RNA methyltransferase TrmH family group 3
FOC70_RS03815	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FOC70_RS03820	ENOG4108JU6	CBS domain protein
FOC70_RS03825	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
FOC70_RS03830	ENOG4105DAP	Nicotinate phosphoribosyltransferase
FOC70_RS03835	ENOG4105C59	p-type ATPase
FOC70_RS03845	ENOG4105VPX	protein, conserved in bacteria
FOC70_RS03855	ENOG4108RS6	transposase
FOC70_RS03865	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
FOC70_RS03870	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
FOC70_RS03880	ENOG4105C5I	Dehydrogenase
FOC70_RS03900	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
FOC70_RS03905	ENOG4108RS6	transposase
FOC70_RS03915	ENOG4105UQX	Mate efflux family protein
FOC70_RS03920	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FOC70_RS03925	ENOG4105C8N	cysteinyl-tRNA synthetase
FOC70_RS03935	ENOG4105EPR	degv family
FOC70_RS03945	ENOG4107R6U	sodium dicarboxylate symporter
FOC70_RS03955	ENOG4105DFU	Cell wall formation (By similarity)
FOC70_RS03990	ENOG4105EZ5	reductase
FOC70_RS03995	ENOG41080XV	Thioredoxin
FOC70_RS04010	ENOG4108K88	Membrane
FOC70_RS04025	ENOG4105BZG	amino acid carrier protein
FOC70_RS04030	ENOG4108RS6	transposase
FOC70_RS04050	ENOG4105C9X	ppx gppa phosphatase
FOC70_RS04055	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
FOC70_RS04065	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FOC70_RS04080	ENOG4105CMQ	Chloride channel
FOC70_RS04100	ENOG4105D8X	mechanosensitive ion channel
FOC70_RS04105	ENOG4105VDK	protein, conserved in bacteria
FOC70_RS04125	ENOG4105CEU	Arginine dihydrolase
FOC70_RS04130	ENOG4105DBV	ornithine carbamoyltransferase
FOC70_RS04140	ENOG4105Q2H	domain protein
FOC70_RS04145	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
FOC70_RS04155	ENOG4105CKU	formyltetrahydrofolate synthetase
FOC70_RS04160	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
FOC70_RS04165	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
FOC70_RS04170	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOC70_RS04175	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOC70_RS04185	ENOG4105C0H	protease
FOC70_RS04195	ENOG4105C3K	feS assembly ATPase SufC
FOC70_RS04200	ENOG4105DIW	FeS assembly protein SUFB
FOC70_RS04215	ENOG4107YH3	SUF system FeS assembly protein, NifU family
FOC70_RS04220	ENOG4108RS6	transposase
FOC70_RS04225	ENOG4105E3H	phosphoglycerate mutase
FOC70_RS04230	ENOG4107QPK	)-transporter
FOC70_RS04235	ENOG4107RSM	transcriptional regulator
FOC70_RS04255	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
FOC70_RS04260	ENOG4108JA2	transcriptioN-repair coupling factor
FOC70_RS04270	ENOG4105K70	DNA-binding protein
FOC70_RS04280	ENOG4108JYZ	YitT family
FOC70_RS04285	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
FOC70_RS04295	ENOG4107RN3	metallophosphoesterase
FOC70_RS04310	ENOG4108WUZ	(ABC) transporter
FOC70_RS04315	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
FOC70_RS04320	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
FOC70_RS04325	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FOC70_RS04330	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FOC70_RS04360	ENOG4105DA5	(ABC) transporter
FOC70_RS04375	ENOG4105C6K	Malic enzyme
FOC70_RS04380	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
FOC70_RS04385	ENOG4105E5D	amino acid
FOC70_RS04390	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
FOC70_RS04405	ENOG4107YV9	domain protein
FOC70_RS04410	ENOG4105C7W	Xanthine dehydrogenase
FOC70_RS04415	ENOG4105CK2	sodium dicarboxylate symporter
FOC70_RS04420	ENOG4105C3F	Signal peptidase i
FOC70_RS04425	ENOG4108RS6	transposase
FOC70_RS04430	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
FOC70_RS04445	ENOG4105C6E	dna polymerase iii
FOC70_RS04450	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
FOC70_RS04455	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
FOC70_RS04470	ENOG4107QY8	reductase
FOC70_RS04475	ENOG4105EGD	dinuclear metal center protein, YbgI family
FOC70_RS04485	ENOG4105CBX	hi0933 family
FOC70_RS04495	ENOG4108IJ0	Aspartate ammonia-lyase
FOC70_RS04505	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
FOC70_RS04510	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
FOC70_RS04520	ENOG4105K5M	30s ribosomal protein S16
FOC70_RS04525	ENOG4105VB6	UPF0109 protein
FOC70_RS04530	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
FOC70_RS04535	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
FOC70_RS04540	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
FOC70_RS04545	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
FOC70_RS04550	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FOC70_RS04555	ENOG4105VFF	UPF0102 protein
FOC70_RS04560	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
FOC70_RS04565	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
FOC70_RS04570	ENOG4105WDJ	50S ribosomal protein L33
FOC70_RS04575	ENOG4105PM1	preprotein translocase subunit SecE
FOC70_RS04580	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
FOC70_RS04585	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
FOC70_RS04590	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
FOC70_RS04595	ENOG4105C02	permease
FOC70_RS04600	ENOG4108VZM	50s ribosomal protein L10
FOC70_RS04605	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
FOC70_RS04610	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
FOC70_RS04615	ENOG4105F8V	Hydrolase, tatD family
FOC70_RS04625	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FOC70_RS04640	ENOG4105CJW	magnesium transporter
FOC70_RS04655	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
FOC70_RS04665	ENOG4105DFM	M18 family aminopeptidase
FOC70_RS04995	ENOG4105IEH	endo-beta-N-acetylglucosaminidase
FOC70_RS05245	ENOG4105IEH	endo-beta-N-acetylglucosaminidase
FOC70_RS05305	ENOG4105C3J	Cysteine desulfurase
FOC70_RS05310	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
FOC70_RS05315	ENOG4108V0P	LemA family
FOC70_RS05330	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FOC70_RS05335	ENOG4105F38	ABC transporter, permease
FOC70_RS05340	ENOG4105D38	putrescine abc transporter
FOC70_RS05345	ENOG4107RUE	extracellular solute-binding protein family 1
FOC70_RS05355	ENOG4105C4R	Atp-dependent dna helicase
FOC70_RS05360	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
FOC70_RS05370	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
FOC70_RS05375	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FOC70_RS05380	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
FOC70_RS05395	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
FOC70_RS05400	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
FOC70_RS05405	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
FOC70_RS05430	ENOG4105J5G	Transferase hexapeptide repeat containing protein
FOC70_RS05435	ENOG4107QQG	Dehydrogenase
FOC70_RS05455	ENOG4105VBF	alkaline shock protein
FOC70_RS05460	ENOG4105EPR	degv family
FOC70_RS05465	ENOG4105BZU	Histidine kinase
FOC70_RS05470	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FOC70_RS05480	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FOC70_RS05485	ENOG4105E2Z	phosphate ABC transporter (Permease
FOC70_RS05490	ENOG4105C8U	phosphate abc transporter
FOC70_RS05500	ENOG4105HDK	L-asparaginase
FOC70_RS05515	ENOG4105EI2	Pseudouridine synthase
FOC70_RS05520	ENOG4105C22	threonyL-tRNA synthetase
FOC70_RS05525	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FOC70_RS05530	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
FOC70_RS05535	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FOC70_RS05540	ENOG4105BZU	Histidine kinase
FOC70_RS05575	ENOG4108V6E	Cell division protein mraZ
FOC70_RS05580	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
FOC70_RS05590	ENOG4105CJN	penicillin-binding protein
FOC70_RS05595	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
FOC70_RS05605	ENOG4105CNI	cell division protein FtsW
FOC70_RS05610	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
FOC70_RS05620	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
FOC70_RS05625	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
FOC70_RS05635	ENOG4105C5S	asparaginyl-tRNA synthetase
FOC70_RS05640	ENOG4105C8T	Leucyl-tRNA synthetase
FOC70_RS05645	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
FOC70_RS05650	ENOG4105C02	permease
FOC70_RS05655	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
FOC70_RS05660	ENOG4105VBH	UPF0297 protein
FOC70_RS05675	ENOG4105I3K	Ferric uptake regulator, Fur family
FOC70_RS05680	ENOG4105CN5	Metallo-Beta-Lactamase
FOC70_RS05695	ENOG4105CFP	Peptidase U32
FOC70_RS05705	ENOG4105DFA	alanine racemase domain protein
FOC70_RS05710	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
FOC70_RS05720	ENOG4105DBK	s4 domain protein
FOC70_RS05725	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
FOC70_RS05735	ENOG4105C34	Pseudouridine synthase
FOC70_RS05740	ENOG4105EPR	degv family
FOC70_RS05750	ENOG4105IEH	endo-beta-N-acetylglucosaminidase
FOC70_RS05780	ENOG4105D3R	alkyl hydroperoxide reductase
FOC70_RS05785	ENOG4105ENA	helicase
FOC70_RS05795	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
FOC70_RS05800	ENOG4105E0C	molybdate abc transporter
FOC70_RS05810	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
FOC70_RS05825	ENOG4105DSJ	YicC domain protein
FOC70_RS05830	ENOG4105KC4	UPF0296 protein
FOC70_RS05835	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
FOC70_RS05840	ENOG41067UH	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
FOC70_RS05845	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
FOC70_RS05850	ENOG4105C25	Primosomal protein n'
FOC70_RS05855	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FOC70_RS05860	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
FOC70_RS05870	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
FOC70_RS05875	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
FOC70_RS05885	ENOG4105D9P	serine threonine protein kinase
FOC70_RS05890	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
FOC70_RS05895	ENOG4105DJV	ribulose-phosphate 3-epimerase
FOC70_RS05910	ENOG4105VB9	50S ribosomal protein l28
FOC70_RS05925	ENOG4105CB5	ATP-dependent DNA helicase recG
FOC70_RS05930	ENOG4106H78	methyltransferase
FOC70_RS05935	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
FOC70_RS05945	ENOG4108Z29	Flavodoxin
FOC70_RS05960	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FOC70_RS05975	ENOG4105CDE	UPF0348 protein
FOC70_RS06015	ENOG4105CUT	histidyl-tRNA synthetase
FOC70_RS06020	ENOG4105C22	threonyL-tRNA synthetase
FOC70_RS06025	ENOG4105BZ1	(ABC) transporter
FOC70_RS06030	ENOG4105BZ1	(ABC) transporter
FOC70_RS06040	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
FOC70_RS06045	ENOG4105VJV	50s ribosomal protein L35
FOC70_RS06050	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
FOC70_RS06060	ENOG4108B02	Modulates RecA activity (By similarity)
FOC70_RS06090	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
FOC70_RS06095	ENOG4105CE9	30S ribosomal protein S2
FOC70_RS06100	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
FOC70_RS06105	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
FOC70_RS06110	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
FOC70_RS06115	ENOG4105K4H	Nlp p60 protein
FOC70_RS06120	ENOG4105KQC	Competence protein
FOC70_RS06125	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
FOC70_RS06130	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FOC70_RS06135	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
FOC70_RS06140	ENOG4107104	thymidine kinase
FOC70_RS06145	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
FOC70_RS06150	ENOG4105CNI	cell division protein FtsW
FOC70_RS06155	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
FOC70_RS06160	ENOG4105CSM	endonuclease III
FOC70_RS06165	ENOG4105CXT	aspartate transcarbamylase
FOC70_RS06180	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
FOC70_RS06185	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
FOC70_RS06190	ENOG4107W93	Dihydroorotate dehydrogenase
FOC70_RS06195	ENOG4107XPQ	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
FOC70_RS06200	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
FOC70_RS06205	ENOG4105KNE	Phosphatidate cytidylyltransferase
FOC70_RS06210	ENOG4105DZP	Membrane-associated zinc metalloprotease
FOC70_RS06220	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
FOC70_RS06225	ENOG4105C9A	Phoh family
FOC70_RS06230	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
FOC70_RS06235	ENOG4107YR5	Diacylglycerol kinase
FOC70_RS06255	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
FOC70_RS06260	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
FOC70_RS06270	ENOG41080P2	Phosphatase
FOC70_RS06275	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FOC70_RS06280	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
FOC70_RS06285	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
FOC70_RS06290	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
FOC70_RS06295	ENOG4105CXI	aluminum resistance protein
FOC70_RS06300	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
FOC70_RS06310	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FOC70_RS06320	ENOG4105DB7	PHP domain protein
FOC70_RS06325	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
FOC70_RS06340	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FOC70_RS06350	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
FOC70_RS06355	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
FOC70_RS06365	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
FOC70_RS06370	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FOC70_RS06375	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
FOC70_RS06380	ENOG4105DTN	riboflavin biosynthesis protein ribF
FOC70_RS06385	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
FOC70_RS06390	ENOG4105SFS	phosphoesterase RecJ domain protein
FOC70_RS06395	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
FOC70_RS06400	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
FOC70_RS06405	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
FOC70_RS06410	ENOG4105CHV	Transcription elongation factor NusA
FOC70_RS06415	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
FOC70_RS06425	ENOG4105DI5	UPF0365 protein
FOC70_RS06435	ENOG4105VCC	30S ribosomal protein S21
FOC70_RS06440	ENOG4107YU2	histidine triad (hIT) protein
FOC70_RS06445	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FOC70_RS06460	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FOC70_RS06465	ENOG4105CFG	Acts as a chaperone (By similarity)
FOC70_RS06475	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
FOC70_RS06480	ENOG4105CSA	Coproporphyrinogen iii oxidase
FOC70_RS06485	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
FOC70_RS06495	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
FOC70_RS06505	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
FOC70_RS06510	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
FOC70_RS06520	ENOG4105CP7	Triose-phosphate isomerase
FOC70_RS06525	ENOG4105BZA	Phosphoglycerate kinase
FOC70_RS06540	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
FOC70_RS06545	ENOG4105CV1	Transketolase (EC 2.2.1.1)
FOC70_RS06550	ENOG4105C79	DNA protecting protein DprA
FOC70_RS06565	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
FOC70_RS06570	ENOG4108TV1	Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity)
FOC70_RS06580	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
FOC70_RS06585	ENOG4105VEQ	Cold shock protein
FOC70_RS06595	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
FOC70_RS06600	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
FOC70_RS06605	ENOG4105C5X	domain protein
FOC70_RS06610	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
FOC70_RS06615	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FOC70_RS06620	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
FOC70_RS06625	ENOG4105VIE	preprotein translocase, subunit YajC
FOC70_RS06630	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
FOC70_RS06635	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
FOC70_RS06640	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
FOC70_RS06645	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
FOC70_RS06650	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
FOC70_RS06655	ENOG4105CHR	reductase
FOC70_RS06660	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FOC70_RS06665	ENOG4108YBA	Histidine kinase
FOC70_RS06685	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FOC70_RS06690	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
FOC70_RS06695	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
FOC70_RS06700	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FOC70_RS06705	ENOG4105F6E	Acyl-transferase
FOC70_RS06715	ENOG4105CBX	hi0933 family
FOC70_RS06730	ENOG4105FE9	pseudouridine synthase
FOC70_RS06735	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
FOC70_RS06740	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
FOC70_RS06745	ENOG4108Z4T	Peptidase M50
FOC70_RS06750	ENOG4108YZ4	nudix hydrolase
FOC70_RS06755	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
FOC70_RS06760	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
FOC70_RS06765	ENOG4105DX0	Hemolysin A
FOC70_RS06775	ENOG41086MA	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FOC70_RS06780	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FOC70_RS06785	ENOG4105M7K	Involved in the transcription termination process (By similarity)
FOC70_RS06795	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FOC70_RS06810	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
FOC70_RS06815	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FOC70_RS06820	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
FOC70_RS06825	ENOG41067VY	50S ribosomal protein L32
FOC70_RS06830	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
FOC70_RS06835	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
FOC70_RS06840	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
FOC70_RS06845	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
FOC70_RS06855	ENOG4105CUZ	uba thif-type nad fad binding protein
FOC70_RS06860	ENOG4105C9M	aspartyl-trna synthetase
FOC70_RS06865	ENOG4105CJR	Integral membrane protein (MviN
FOC70_RS06885	ENOG4105C75	arginyL-tRNA synthetase
FOC70_RS06890	ENOG4105C98	muts2 protein
FOC70_RS06895	ENOG4105CFP	Peptidase U32
FOC70_RS06905	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
FOC70_RS06910	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
FOC70_RS06915	ENOG4108RWN	rrna methyltransferase
FOC70_RS06925	ENOG4105CZN	Potassium uptake protein
FOC70_RS06930	ENOG4105CU9	asparagine synthetase A
FOC70_RS06935	ENOG4105K4W	Could be involved in septation (By similarity)
FOC70_RS06940	ENOG4105W2C	Glycosyl transferase
FOC70_RS06950	ENOG4105BZF	Glycosyl transferase (Group 1
FOC70_RS06970	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOC70_RS06975	ENOG4105EEI	dihydropteroate synthase
FOC70_RS06980	ENOG4105KFW	domain protein
FOC70_RS06985	ENOG4105EUJ	GTP cyclohydrolase i
FOC70_RS06995	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
FOC70_RS07000	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FOC70_RS07005	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FOC70_RS07015	ENOG4105D82	Glutamate dehydrogenase
FOC70_RS07020	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
FOC70_RS07030	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
FOC70_RS07035	ENOG4105CDY	transcriptional regulatory protein
FOC70_RS07040	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
FOC70_RS07045	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
FOC70_RS07050	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
FOC70_RS07075	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
FOC70_RS07085	ENOG4105JFG	SpoIID LytB domain protein
FOC70_RS07090	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
FOC70_RS07100	ENOG4108JYZ	YitT family
FOC70_RS07110	ENOG4105FDK	ABC transporter
FOC70_RS07115	ENOG4105DSE	periplasmic solute binding protein
FOC70_RS07125	ENOG4105BZU	Histidine kinase
FOC70_RS07130	ENOG4105ETX	regulatoR
FOC70_RS07135	ENOG4107WD8	ABC transporter, permease
FOC70_RS07145	ENOG4107WD8	ABC transporter, permease
FOC70_RS07155	ENOG4108RG0	uracil-dna glycosylase
FOC70_RS07175	ENOG4105EHG	Permease protein
FOC70_RS07180	ENOG4105DVA	methyltransferase
FOC70_RS07195	ENOG4108JJB	ABC transporter
FOC70_RS07210	ENOG4105YA8	Transcriptional regulator
FOC70_RS07220	ENOG4105MU5	relaxase mobilization nuclease domain protein
FOC70_RS07225	ENOG4108JJB	ABC transporter
FOC70_RS07245	ENOG4105BZ1	(ABC) transporter
FOC70_RS07295	ENOG4105CE1	Ferrous iron transport protein b
FOC70_RS07305	ENOG4105BZ1	(ABC) transporter
FOC70_RS07310	ENOG4105BZ1	(ABC) transporter
FOC70_RS07315	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
FOC70_RS07330	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FOC70_RS07345	ENOG4105M6F	mutator MutT protein
FOC70_RS07375	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
FOC70_RS07410	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FOC70_RS07465	ENOG4105EKQ	RNA-directed DNA polymerase
FOC70_RS07530	ENOG4105BZ1	(ABC) transporter
FOC70_RS07535	ENOG4105BZ1	(ABC) transporter
FOC70_RS07540	ENOG4108JJB	ABC transporter
FOC70_RS07555	ENOG4108IG5	Transcriptional regulator
FOC70_RS07580	ENOG4106CVF	DNA replication protein
FOC70_RS07590	ENOG4105CRK	lysyL-tRNA synthetase
FOC70_RS07595	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FOC70_RS07600	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
FOC70_RS07605	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
FOC70_RS07610	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
FOC70_RS07625	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FOC70_RS07630	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
FOC70_RS07635	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
FOC70_RS07640	ENOG41060GV	RNA binding s1 domain protein
FOC70_RS07650	ENOG41082I2	s4 domain protein
FOC70_RS07655	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
FOC70_RS07665	ENOG4105CTQ	phosphohexokinase
FOC70_RS07670	ENOG4105C0B	DNA polymerase III (alpha subunit)
FOC70_RS07675	ENOG4105CIE	May be required for sporulation (By similarity)
FOC70_RS07680	ENOG41062IR	nudix hydrolase
FOC70_RS07710	ENOG4105UIB	(ABC) transporter
FOC70_RS07715	ENOG4108JQ9	ABC transporter
FOC70_RS07720	ENOG4105DIH	basic membrane
FOC70_RS07725	ENOG4107QN2	dihydrolipoyl dehydrogenase
FOC70_RS07730	ENOG4105C2W	permease
FOC70_RS07750	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
FOC70_RS07755	ENOG4105KZ7	phosphocarrier protein hpr
FOC70_RS07760	ENOG4105ETE	Transcriptional regulator (LacI family
FOC70_RS07765	ENOG4105CBD	Diacylglycerol kinase
FOC70_RS07790	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
FOC70_RS07795	ENOG4105CJN	penicillin-binding protein
FOC70_RS07810	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
FOC70_RS07825	ENOG4108IUM	Glycogen debranching enzyme
FOC70_RS07835	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
FOC70_RS07840	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
FOC70_RS07845	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
FOC70_RS07850	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
FOC70_RS07855	ENOG4105CY0	Metallo-Beta-Lactamase
FOC70_RS07860	ENOG4105KGF	protein, YerC YecD
FOC70_RS07865	ENOG4105CI3	gtp-binding protein typa
FOC70_RS07875	ENOG4105VCQ	rubredoxin
FOC70_RS07880	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
FOC70_RS07885	ENOG41090A1	ferritin
FOC70_RS07910	ENOG4105K56	Transcriptional regulator
FOC70_RS07915	ENOG4107Z5F	Aminotransferase class IV
FOC70_RS07920	ENOG4105CRQ	synthase (Component I)
FOC70_RS07925	ENOG4105DDQ	anthranilate synthase
FOC70_RS07930	ENOG4107RBB	ABC transporter, permease
FOC70_RS07935	ENOG4105C19	ABC transporter
FOC70_RS07945	ENOG4105CIN	aminoacyl-histidine dipeptidase
FOC70_RS07950	ENOG4105KTH	gatB Yqey
FOC70_RS07965	ENOG4105CEV	competence damage-inducible protein
FOC70_RS07985	ENOG4105CJZ	response regulator
FOC70_RS07990	ENOG4105C2W	permease
FOC70_RS07995	ENOG4107XWZ	ferric uptake regulator
FOC70_RS08005	ENOG4105D1Q	UPF0246 protein
FOC70_RS08010	ENOG4105BZ1	(ABC) transporter
FOC70_RS08015	ENOG4108JJ9	ABC, transporter
FOC70_RS08020	ENOG4105VXR	cytoplasmic protein
FOC70_RS08025	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FOC70_RS08030	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
FOC70_RS08040	ENOG4105KXQ	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FOC70_RS08050	ENOG41083MH	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FOC70_RS08070	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
FOC70_RS08075	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FOC70_RS08085	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
FOC70_RS08090	ENOG4105DCG	PHP domain protein
FOC70_RS08095	ENOG4105D4A	Cell wall formation (By similarity)
FOC70_RS08100	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
FOC70_RS08105	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
FOC70_RS08110	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
FOC70_RS08115	ENOG4105CBJ	Metal-dependent enzyme
FOC70_RS08120	ENOG41082DI	50s ribosomal protein l31
FOC70_RS08125	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
FOC70_RS08130	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
FOC70_RS08180	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FOC70_RS08185	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FOC70_RS08195	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FOC70_RS08205	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FOC70_RS08240	ENOG4105CDA	abc transporter atp-binding protein
FOC70_RS08245	ENOG4105E5Q	amino acid AbC transporter
FOC70_RS08250	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FOC70_RS08255	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
FOC70_RS08260	ENOG4108JJB	ABC transporter
FOC70_RS08265	ENOG4108JJB	ABC transporter
FOC70_RS08270	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FOC70_RS08275	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FOC70_RS08295	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
FOC70_RS08300	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
FOC70_RS08310	ENOG4105MA4	psp1 domain protein
FOC70_RS08315	ENOG4105FA2	dna polymerase iii
FOC70_RS08320	ENOG4105X0R	protein from nitrogen regulatory protein P-II
FOC70_RS08325	ENOG4105X0R	protein from nitrogen regulatory protein P-II
FOC70_RS08330	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
FOC70_RS08335	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
FOC70_RS08345	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
FOC70_RS08350	ENOG4105C59	p-type ATPase
FOC70_RS08365	ENOG4108VXD	carboxy-peptidase
FOC70_RS08375	ENOG4105CM2	brancheD-chain amino acid aminotransferase
FOC70_RS08380	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
FOC70_RS08390	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
FOC70_RS08400	ENOG4105VKD	bioY protein
FOC70_RS08405	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
FOC70_RS08415	ENOG4105CIZ	coA-substrate-specific enzyme activase
FOC70_RS08420	ENOG4105N5T	Radical SAM Protein
FOC70_RS08425	ENOG4108Z6B	deaminase
FOC70_RS08430	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FOC70_RS08435	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FOC70_RS08440	ENOG4105EKQ	RNA-directed DNA polymerase
FOC70_RS08460	ENOG4107QIZ	NADH dehydrogenase
FOC70_RS08465	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
FOC70_RS08470	ENOG4105EM7	Selenocysteine-specific translation elongation factor
FOC70_RS08480	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
FOC70_RS08490	ENOG4108IUX	(ABC) transporter
FOC70_RS08495	ENOG4108UYE	Lactoylglutathione lyase
FOC70_RS08500	ENOG4105DPN	Oligoendopeptidase f
FOC70_RS08520	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FOC70_RS08525	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
FOC70_RS08530	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
FOC70_RS08550	ENOG4107WUB	V-type ATPase 116 kDa subunit
FOC70_RS08585	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
FOC70_RS08590	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
FOC70_RS08615	ENOG4105E4C	Lytic transglycosylase catalytic
FOC70_RS08620	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
FOC70_RS08625	ENOG4105CAK	Cell division ATP-binding protein ftsE
FOC70_RS08630	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
FOC70_RS08635	ENOG4105CJ1	ABC, transporter
FOC70_RS08655	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
FOC70_RS08660	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FOC70_RS08665	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
FOC70_RS08695	ENOG4105CIZ	coA-substrate-specific enzyme activase
FOC70_RS08705	ENOG4105C7N	Xanthine uracil vitamin C permease
FOC70_RS08710	ENOG4105C5H	ABC transporter
FOC70_RS08715	ENOG4108RE9	Phosphodiesterase
FOC70_RS08720	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FOC70_RS08725	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
FOC70_RS08730	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
FOC70_RS08735	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
FOC70_RS08740	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOC70_RS08760	ENOG4105CE1	Ferrous iron transport protein b
FOC70_RS08770	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FOC70_RS08780	ENOG41072GX	Peptidase M22 Glycoprotease
FOC70_RS08785	ENOG4105K8N	protein family UPF0079, ATPase
FOC70_RS08795	ENOG4105DFM	M18 family aminopeptidase
FOC70_RS08805	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
FOC70_RS08810	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
FOC70_RS08825	ENOG4105C8B	TIGR00159 family
FOC70_RS08830	ENOG41080Z8	PHOSPHOCARRIER protein
FOC70_RS08835	ENOG4108RAC	Rubrerythrin
FOC70_RS08840	ENOG4105DFF	Rod shape-determining protein mreb
FOC70_RS08845	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
FOC70_RS08850	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
FOC70_RS08855	ENOG4105CTP	PilT protein domain protein
FOC70_RS08860	ENOG4108VJ1	Transcriptional regulator (CarD family
FOC70_RS08865	ENOG41069ER	domain protein
FOC70_RS08875	ENOG4105D4P	Coproporphyrinogen iii oxidase
FOC70_RS08880	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FOC70_RS08885	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
FOC70_RS08890	ENOG4105E2X	shikimate dehydrogenase
FOC70_RS08895	ENOG4105CQC	Prephenate dehydratase
FOC70_RS08905	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
FOC70_RS08915	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
FOC70_RS08935	ENOG4108JQ7	(ABC) transporter
FOC70_RS08945	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FOC70_RS08950	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FOC70_RS08955	ENOG4108J59	Extracellular solute-binding protein, family 5
FOC70_RS08995	ENOG4107RCV	ABC transporter, permease
FOC70_RS09035	ENOG4107QID	Threonine synthase
FOC70_RS09040	ENOG4107QW4	alcohol dehydrogenase
FOC70_RS09045	ENOG4105C5H	ABC transporter
FOC70_RS09065	ENOG4105DQ6	Transposase
FOC70_RS09080	ENOG4108IUW	ABC transporter
FOC70_RS09130	ENOG4105BZ1	(ABC) transporter
FOC70_RS09135	ENOG4105BZ1	(ABC) transporter
FOC70_RS09145	ENOG4105D5G	Transposase
FOC70_RS09150	ENOG4105D5G	Transposase
FOC70_RS09155	ENOG4108JJB	ABC transporter
FOC70_RS09180	ENOG4105C0W	non-ribosomal peptide synthetase
FOC70_RS09185	ENOG4105C0W	non-ribosomal peptide synthetase
FOC70_RS09190	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
FOC70_RS09205	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
FOC70_RS09210	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
FOC70_RS09215	ENOG4105E2X	shikimate dehydrogenase
FOC70_RS09220	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
FOC70_RS09225	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
FOC70_RS09230	ENOG4105D49	3-dehydroquinate synthase
FOC70_RS09270	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FOC70_RS09370	ENOG4105DFS	Conserved Protein
FOC70_RS09430	ENOG4105DA5	(ABC) transporter
FOC70_RS09455	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
FOC70_RS09470	ENOG4105BZ1	(ABC) transporter
FOC70_RS09485	ENOG4105CXN	decarboxylase
FOC70_RS09490	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
FOC70_RS09495	ENOG4105CZV	ABC transporter
FOC70_RS09510	ENOG4105CAH	Chromate
FOC70_RS09525	ENOG4105DM4	PTS System
FOC70_RS09530	ENOG4105DE4	1-phosphofructokinase
FOC70_RS09540	ENOG4105EWC	Purine nucleoside phosphorylase
FOC70_RS09545	ENOG4105HMI	Membrane
FOC70_RS09555	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
FOC70_RS09560	ENOG4105DF9	Lipoate-protein, ligase
FOC70_RS09585	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
FOC70_RS09640	ENOG4108IUW	ABC transporter
FOC70_RS09660	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FOC70_RS09670	ENOG4105D01	(LipO)protein
FOC70_RS09675	ENOG4108UMI	ABC transporter, permease
FOC70_RS09690	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FOC70_RS09695	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FOC70_RS09705	ENOG4108UQV	Membrane
FOC70_RS09715	ENOG4105EPD	Oligopeptide transporter, Opt family
FOC70_RS09755	ENOG4105C26	Dehydrogenase
FOC70_RS09760	ENOG4107YJ4	chain length determinant protein
FOC70_RS09770	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
FOC70_RS09805	ENOG4107YB6	acetyltransferase, (GNAT) family
FOC70_RS09845	ENOG4105VEQ	Cold shock protein
FOC70_RS09875	ENOG4105D3W	isochorismatase
FOC70_RS09880	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
FOC70_RS09890	ENOG4105DQ6	Transposase
FOC70_RS09900	ENOG4105DUM	transcriptional regulator, lysR family
FOC70_RS09910	ENOG4105DQ6	Transposase
FOC70_RS09920	ENOG4105C83	adenylosuccinate lyase
FOC70_RS09925	ENOG4107QNG	Phosphoribosylglycinamide synthetase
FOC70_RS09935	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
FOC70_RS09945	ENOG4105C8V	SAICAR synthetase
FOC70_RS09970	ENOG4108QEG	Membrane
FOC70_RS09985	ENOG4105KT7	mgtC SapB transporter
FOC70_RS10020	ENOG41089UC	methyltransferase, type 11