locus-tag	class	description
EI427_RS00005	COG2198	Histidine kinase
EI427_RS00005	COG0784	Response regulator, receiver
EI427_RS00005	COG0643	Histidine kinase
EI427_RS00020	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EI427_RS00025	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EI427_RS00030	COG0714	Associated with various cellular activities
EI427_RS00080	COG3956	TIGRFAM MazG family protein
EI427_RS00090	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EI427_RS00105	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EI427_RS00110	COG0255	Belongs to the universal ribosomal protein uL29 family
EI427_RS00115	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EI427_RS00120	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EI427_RS00125	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EI427_RS00130	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EI427_RS00135	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EI427_RS00140	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EI427_RS00145	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EI427_RS00150	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EI427_RS00155	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EI427_RS00160	COG1841	ribosomal large subunit assembly
EI427_RS00165	COG0200	Binds to the 23S rRNA
EI427_RS00170	COG0201	protein transport
EI427_RS00180	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EI427_RS00185	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EI427_RS00190	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EI427_RS00195	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EI427_RS00200	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EI427_RS00205	COG0202	RNA polymerase activity
EI427_RS00210	COG0203	ribosomal protein L17
EI427_RS00215	COG0505	Belongs to the CarA family
EI427_RS00255	COG1538	Outer membrane efflux protein
EI427_RS00270	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EI427_RS00280	COG2255	four-way junction helicase activity
EI427_RS00295	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EI427_RS00300	COG4771	TonB-dependent receptor
EI427_RS00315	COG1404	Belongs to the peptidase S8 family
EI427_RS00340	COG4942	peptidase
EI427_RS00360	COG0356	it plays a direct role in the translocation of protons across the membrane
EI427_RS00365	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EI427_RS00370	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EI427_RS00375	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EI427_RS00380	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EI427_RS00385	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EI427_RS00400	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EI427_RS00430	COG0825	malonyl-CoA metabolic process
EI427_RS00435	COG1283	sodium-dependent phosphate transmembrane transporter activity
EI427_RS00440	COG0123	including yeast histone deacetylase and acetoin utilization protein
EI427_RS00450	COG0492	ferredoxin-NADP+ reductase activity
EI427_RS00490	COG2885	chlorophyll binding
EI427_RS00495	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EI427_RS00500	COG0159	tryptophan synthase activity
EI427_RS00520	COG0508	dehydrogenase complex catalyzes the overall conversion of
EI427_RS00530	COG1011	Hydrolase
EI427_RS00535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EI427_RS00550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EI427_RS00580	COG2207	Transcriptional regulator
EI427_RS00610	COG3590	peptidase
EI427_RS00615	COG0659	secondary active sulfate transmembrane transporter activity
EI427_RS00680	COG0583	DNA-binding transcription factor activity
EI427_RS00685	COG2226	methyltransferase
EI427_RS00690	COG1874	Beta-galactosidase
EI427_RS00690	COG0366	Alpha amylase catalytic
EI427_RS00700	COG1082	Xylose isomerase domain protein TIM barrel
EI427_RS00730	COG3279	Response regulator of the LytR AlgR family
EI427_RS00735	COG3275	phosphorelay sensor kinase activity
EI427_RS00800	COG3119	arylsulfatase activity
EI427_RS00820	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EI427_RS00835	COG1607	acyl-coa hydrolase
EI427_RS00845	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EI427_RS00905	COG1418	mRNA catabolic process
EI427_RS00910	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EI427_RS00925	COG1253	flavin adenine dinucleotide binding
EI427_RS00930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EI427_RS00935	COG0336	Belongs to the RNA methyltransferase TrmD family
EI427_RS00940	COG0470	DNA polymerase III
EI427_RS00950	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EI427_RS00955	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EI427_RS00980	COG0022	dehydrogenase e1 component
EI427_RS00980	COG0508	dehydrogenase complex catalyzes the overall conversion of
EI427_RS00990	COG0101	tRNA pseudouridine synthase activity
EI427_RS01030	COG2010	Cytochrome c
EI427_RS01050	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EI427_RS01080	COG1131	(ABC) transporter
EI427_RS01105	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EI427_RS01110	COG1214	PFAM Peptidase M22, glycoprotease
EI427_RS01115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EI427_RS01130	COG1028	Short-chain dehydrogenase reductase Sdr
EI427_RS01135	COG2195	Cleaves the N-terminal amino acid of tripeptides
EI427_RS01165	COG4372	Transposase
EI427_RS01215	COG0069	glutamate synthase activity
EI427_RS01220	COG0628	permease
EI427_RS01230	COG0235	Class ii aldolase
EI427_RS01240	COG0450	alkyl hydroperoxide reductase
EI427_RS01245	COG3250	beta-galactosidase activity
EI427_RS01255	COG1917	Cupin 2, conserved barrel domain protein
EI427_RS01255	COG4977	sequence-specific DNA binding
EI427_RS01270	COG4771	TonB-dependent receptor
EI427_RS01285	COG0668	transmembrane transport
EI427_RS01325	COG0653	protein targeting
EI427_RS01340	COG0189	ligase activity
EI427_RS01365	COG3279	Response regulator of the LytR AlgR family
EI427_RS01390	COG0596	Alpha beta hydrolase
EI427_RS01400	COG1231	oxidoreductase activity
EI427_RS01405	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EI427_RS01410	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EI427_RS01435	COG0739	heme binding
EI427_RS01465	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EI427_RS01515	COG1127	ABC transporter
EI427_RS01520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EI427_RS01530	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EI427_RS01545	COG0668	transmembrane transport
EI427_RS01550	COG1216	Glycosyl transferase, family 2
EI427_RS01560	COG2204	response regulator
EI427_RS01580	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EI427_RS01625	COG1192	Involved in chromosome partitioning
EI427_RS01635	COG1309	transcriptional regulator
EI427_RS01655	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EI427_RS01710	COG1408	metallophosphoesterase
EI427_RS01725	COG1024	Enoyl-CoA hydratase
EI427_RS01730	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EI427_RS01750	COG1752	Esterase of the alpha-beta hydrolase superfamily
EI427_RS01760	COG2176	DNA-directed DNA polymerase activity
EI427_RS01775	COG1573	uracil-dna glycosylase
EI427_RS01790	COG0215	cysteine-tRNA ligase activity
EI427_RS01805	COG0247	lactate metabolic process
EI427_RS01805	COG0277	FAD linked oxidase domain protein
EI427_RS01815	COG0583	DNA-binding transcription factor activity
EI427_RS01825	COG0302	gtp cyclohydrolase
EI427_RS01850	COG2003	Belongs to the UPF0758 family
EI427_RS01885	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EI427_RS01895	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EI427_RS01900	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EI427_RS01905	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EI427_RS01915	COG1022	Amp-dependent synthetase and ligase
EI427_RS01935	COG1774	PSP1 C-terminal conserved region
EI427_RS01940	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EI427_RS01955	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EI427_RS01965	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EI427_RS01980	COG1162	GTPase activity
EI427_RS01990	COG1595	DNA-templated transcription, initiation
EI427_RS02000	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EI427_RS02010	COG1968	undecaprenyl-diphosphatase activity
EI427_RS02015	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EI427_RS02020	COG0196	riboflavin kinase activity
EI427_RS02025	COG1073	alpha beta
EI427_RS02030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EI427_RS02050	COG0366	Alpha amylase catalytic
EI427_RS02060	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EI427_RS02105	COG0004	ammonium transporteR
EI427_RS02125	COG1136	(ABC) transporter
EI427_RS02125	COG0577	efflux transmembrane transporter activity
EI427_RS02145	COG0612	Peptidase, M16
EI427_RS02150	COG2066	Belongs to the glutaminase family
EI427_RS02175	COG4206	TonB-dependent receptor
EI427_RS02195	COG2972	Histidine kinase
EI427_RS02210	COG1136	(ABC) transporter
EI427_RS02215	COG4591	ABC-type transport system involved in lipoprotein release permease component
EI427_RS02250	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EI427_RS02255	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EI427_RS02265	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EI427_RS02330	COG1217	gtp-binding protein TYPA
EI427_RS02350	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EI427_RS02385	COG0688	phosphatidylethanolamine metabolic process
EI427_RS02390	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EI427_RS02390	COG0321	lipoyl(octanoyl) transferase activity
EI427_RS02415	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EI427_RS02420	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EI427_RS02435	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EI427_RS02445	COG2217	Heavy metal translocating P-type atpase
EI427_RS02465	COG1858	cytochrome C peroxidase
EI427_RS02470	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EI427_RS02480	COG4221	oxidoreductase activity
EI427_RS02485	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EI427_RS02490	COG1366	Belongs to the anti-sigma-factor antagonist family
EI427_RS02495	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EI427_RS02510	COG0191	fructose-bisphosphate aldolase activity
EI427_RS02515	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EI427_RS02520	COG0772	Belongs to the SEDS family
EI427_RS02525	COG1752	Esterase of the alpha-beta hydrolase superfamily
EI427_RS02530	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EI427_RS02545	COG0745	RESPONSE REGULATOR receiver
EI427_RS02555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EI427_RS02600	COG0583	DNA-binding transcription factor activity
EI427_RS02610	COG1309	transcriptional regulator
EI427_RS02615	COG3119	arylsulfatase activity
EI427_RS02625	COG3119	arylsulfatase activity
EI427_RS02635	COG0714	Associated with various cellular activities
EI427_RS02655	COG2304	oxidoreductase activity
EI427_RS02700	COG3119	arylsulfatase activity
EI427_RS02710	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EI427_RS02710	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EI427_RS02740	COG0024	Methionine aminopeptidase
EI427_RS02750	COG1028	Short-chain dehydrogenase reductase Sdr
EI427_RS02770	COG0488	(ABC) transporter
EI427_RS02820	COG0488	(ABC) transporter
EI427_RS02825	COG2353	YceI-like domain
EI427_RS02840	COG0076	glutamate decarboxylase activity
EI427_RS02855	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EI427_RS02860	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EI427_RS02875	COG1187	pseudouridine synthase activity
EI427_RS02880	COG1252	NADH dehydrogenase
EI427_RS02885	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EI427_RS02910	COG0519	Catalyzes the synthesis of GMP from XMP
EI427_RS02915	COG1418	mRNA catabolic process
EI427_RS02945	COG0386	Belongs to the glutathione peroxidase family
EI427_RS02955	COG2234	aminopeptidase activity
EI427_RS02970	COG1181	Belongs to the D-alanine--D-alanine ligase family
EI427_RS02985	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EI427_RS02990	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EI427_RS03005	COG0601	transmembrane transport
EI427_RS03010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EI427_RS03020	COG0084	hydrolase, TatD family'
EI427_RS03025	COG0252	asparaginase activity
EI427_RS03030	COG0811	peptide transport
EI427_RS03050	COG1523	belongs to the glycosyl hydrolase 13 family
EI427_RS03060	COG0137	argininosuccinate synthase activity
EI427_RS03065	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EI427_RS03070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EI427_RS03080	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EI427_RS03090	COG0165	Argininosuccinate lyase
EI427_RS03115	COG0662	Cupin 2, conserved barrel domain protein
EI427_RS03115	COG2207	Transcriptional regulator
EI427_RS03150	COG0335	large ribosomal subunit rRNA binding
EI427_RS03210	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EI427_RS03230	COG1131	(ABC) transporter
EI427_RS03235	COG0656	L-ascorbic acid biosynthetic process
EI427_RS03250	COG1595	DNA-templated transcription, initiation
EI427_RS03260	COG0513	Belongs to the DEAD box helicase family
EI427_RS03270	COG2318	DinB family
EI427_RS03275	COG0456	acetyltransferase
EI427_RS03280	COG4106	trans-aconitate 2-methyltransferase activity
EI427_RS03305	COG4895	conserved protein (DUF2196)
EI427_RS03310	COG0513	Belongs to the DEAD box helicase family
EI427_RS03315	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EI427_RS03355	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EI427_RS03355	COG0140	phosphoribosyl-ATP diphosphatase activity
EI427_RS03370	COG0135	phosphoribosylanthranilate isomerase activity
EI427_RS03380	COG4974	Belongs to the 'phage' integrase family
EI427_RS03405	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EI427_RS03445	COG1070	Carbohydrate kinase
EI427_RS03450	COG0277	FAD linked oxidase domain protein
EI427_RS03455	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EI427_RS03475	COG2706	6-phosphogluconolactonase activity
EI427_RS03485	COG3250	beta-galactosidase activity
EI427_RS03490	COG0745	RESPONSE REGULATOR receiver
EI427_RS03490	COG2205	protein histidine kinase activity
EI427_RS03490	COG3292	Two component regulator propeller
EI427_RS03495	COG3119	arylsulfatase activity
EI427_RS03500	COG3119	arylsulfatase activity
EI427_RS03520	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EI427_RS03530	COG4221	oxidoreductase activity
EI427_RS03535	COG1045	serine acetyltransferase
EI427_RS03550	COG0484	heat shock protein binding
EI427_RS03555	COG0318	PFAM AMP-dependent synthetase and ligase
EI427_RS03570	COG0564	pseudouridine synthase activity
EI427_RS03580	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EI427_RS03580	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EI427_RS03590	COG4912	Dna alkylation repair
EI427_RS03630	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EI427_RS03635	COG1959	2 iron, 2 sulfur cluster binding
EI427_RS03645	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EI427_RS03670	COG0436	Aminotransferase
EI427_RS03680	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EI427_RS03690	COG3590	peptidase
EI427_RS03710	COG0564	pseudouridine synthase activity
EI427_RS03725	COG4152	abc transporter atp-binding protein
EI427_RS03730	COG1668	transmembrane transport
EI427_RS03735	COG2871	sodium ion transport
EI427_RS03740	COG1272	protein, Hemolysin III
EI427_RS03755	COG0519	Catalyzes the synthesis of GMP from XMP
EI427_RS03760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EI427_RS03760	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EI427_RS03785	COG0492	ferredoxin-NADP+ reductase activity
EI427_RS03800	COG1678	Uncharacterized ACR, COG1678
EI427_RS03805	COG0339	signal peptide processing
EI427_RS03810	COG0316	Belongs to the HesB IscA family
EI427_RS03820	COG4771	TonB-dependent receptor
EI427_RS03835	COG1472	Belongs to the glycosyl hydrolase 3 family
EI427_RS03850	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EI427_RS03850	COG5180	pathogenesis
EI427_RS03855	COG0195	Participates in both transcription termination and antitermination
EI427_RS03860	COG0779	Required for maturation of 30S ribosomal subunits
EI427_RS03870	COG0579	oxidoreductase
EI427_RS03885	COG0004	ammonium transporteR
EI427_RS03900	COG1116	anion transmembrane transporter activity
EI427_RS03900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EI427_RS03905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EI427_RS03910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EI427_RS03910	COG1116	anion transmembrane transporter activity
EI427_RS03915	COG1116	anion transmembrane transporter activity
EI427_RS03940	COG0667	Aldo Keto reductase
EI427_RS03950	COG0745	RESPONSE REGULATOR receiver
EI427_RS03950	COG2205	protein histidine kinase activity
EI427_RS03950	COG3292	Two component regulator propeller
EI427_RS03960	COG4771	TonB-dependent receptor
EI427_RS03965	COG0702	epimerase
EI427_RS03970	COG3250	beta-galactosidase activity
EI427_RS03990	COG3458	cephalosporin-C deacetylase activity
EI427_RS03995	COG2755	lipolytic protein G-D-S-L family
EI427_RS03995	COG0657	acetylesterase activity
EI427_RS04015	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EI427_RS04020	COG1619	proteins homologs of microcin C7 resistance protein MccF
EI427_RS04040	COG0300	oxidoreductase activity
EI427_RS04045	COG4206	TonB-dependent receptor
EI427_RS04045	COG1629	transport
EI427_RS04065	COG0450	alkyl hydroperoxide reductase
EI427_RS04085	COG1522	sequence-specific DNA binding
EI427_RS04100	COG1288	antiporter activity
EI427_RS04120	COG0281	malic enzyme
EI427_RS04120	COG0280	phosphate acetyltransferase
EI427_RS04125	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EI427_RS04145	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EI427_RS04165	COG1496	oxidoreductase activity
EI427_RS04170	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EI427_RS04195	COG0647	UMP catabolic process
EI427_RS04205	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EI427_RS04210	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EI427_RS04215	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EI427_RS04220	COG2045	Belongs to the ComB family
EI427_RS04230	COG0531	amino acid
EI427_RS04240	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EI427_RS04245	COG2208	phosphoserine phosphatase activity
EI427_RS04250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EI427_RS04265	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EI427_RS04270	COG3959	Transketolase, thiamine diphosphate binding domain
EI427_RS04275	COG4251	negative regulation of phosphorylation
EI427_RS04290	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EI427_RS04300	COG1193	negative regulation of DNA recombination
EI427_RS04310	COG4771	TonB-dependent receptor
EI427_RS04315	COG0702	epimerase
EI427_RS04335	COG2040	homocysteine
EI427_RS04340	COG1022	Amp-dependent synthetase and ligase
EI427_RS04355	COG3119	arylsulfatase activity
EI427_RS04360	COG3119	arylsulfatase activity
EI427_RS04390	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EI427_RS04395	COG1012	belongs to the aldehyde dehydrogenase family
EI427_RS04435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EI427_RS04440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EI427_RS04440	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EI427_RS04455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EI427_RS04460	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EI427_RS04495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EI427_RS04500	COG0484	heat shock protein binding
EI427_RS04515	COG4172	Belongs to the ABC transporter superfamily
EI427_RS04535	COG1858	cytochrome C peroxidase
EI427_RS04545	COG0717	Belongs to the dCTP deaminase family
EI427_RS04565	COG0018	arginyl-trna synthetase
EI427_RS04590	COG0113	porphobilinogen synthase activity
EI427_RS04615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EI427_RS04620	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EI427_RS04630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EI427_RS04635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EI427_RS04640	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EI427_RS04655	COG0297	glycogen (starch) synthase activity
EI427_RS04655	COG0438	transferase activity, transferring glycosyl groups
EI427_RS04700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EI427_RS04715	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EI427_RS04720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EI427_RS04720	COG0543	2 iron, 2 sulfur cluster binding
EI427_RS04725	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EI427_RS04730	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EI427_RS04735	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EI427_RS04780	COG0720	synthase
EI427_RS04810	COG3011	Protein conserved in bacteria
EI427_RS04820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EI427_RS04845	COG0489	protein tyrosine kinase activity
EI427_RS04890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EI427_RS04895	COG0284	orotidine-5'-phosphate decarboxylase activity
EI427_RS04900	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EI427_RS04910	COG3119	arylsulfatase activity
EI427_RS04940	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EI427_RS04945	COG1233	COG1233 Phytoene dehydrogenase and related
EI427_RS04965	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EI427_RS04975	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EI427_RS04980	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EI427_RS04985	COG1960	acyl-CoA dehydrogenase activity
EI427_RS05000	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EI427_RS05005	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EI427_RS05010	COG1349	DNA-binding transcription factor activity
EI427_RS05015	COG1629	transport
EI427_RS05075	COG1082	Xylose isomerase domain protein TIM barrel
EI427_RS05090	COG2837	iron assimilation
EI427_RS05095	COG0110	maltose O-acetyltransferase activity
EI427_RS05105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EI427_RS05120	COG0101	tRNA pseudouridine synthase activity
EI427_RS05130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EI427_RS05145	COG0488	(ABC) transporter
EI427_RS05155	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EI427_RS05165	COG2205	protein histidine kinase activity
EI427_RS05165	COG0784	Response regulator, receiver
EI427_RS05170	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EI427_RS05180	COG0357	Ribosomal RNA small subunit methyltransferase G
EI427_RS05190	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EI427_RS05245	COG0494	nUDIX hydrolase
EI427_RS05250	COG0534	Mate efflux family protein
EI427_RS05275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EI427_RS05295	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EI427_RS05295	COG0617	tRNA 3'-terminal CCA addition
EI427_RS05295	COG0517	IMP dehydrogenase activity
EI427_RS05315	COG1136	(ABC) transporter
EI427_RS05325	COG1609	Transcriptional regulator
EI427_RS05330	COG4206	TonB-dependent receptor
EI427_RS05330	COG1629	transport
EI427_RS05335	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EI427_RS05355	COG0366	Alpha amylase catalytic
EI427_RS05360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EI427_RS05380	COG0737	Belongs to the 5'-nucleotidase family
EI427_RS05385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EI427_RS05390	COG2072	flavoprotein involved in K transport
EI427_RS05435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EI427_RS05475	COG1132	(ABC) transporter
EI427_RS05520	COG1595	DNA-templated transcription, initiation
EI427_RS05540	COG1584	GPR1 FUN34 yaaH family protein
EI427_RS05560	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EI427_RS05565	COG0732	type I restriction modification DNA specificity domain
EI427_RS05585	COG1943	Transposase
EI427_RS05590	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EI427_RS05600	COG1401	restriction endodeoxyribonuclease activity
EI427_RS05665	COG1629	transport
EI427_RS05670	COG1629	transport
EI427_RS05685	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EI427_RS05720	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EI427_RS05730	COG3842	ATPase activity
EI427_RS05780	COG0488	(ABC) transporter
EI427_RS05785	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EI427_RS05790	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EI427_RS05795	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EI427_RS05825	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EI427_RS05840	COG3757	hydrolase, family 25
EI427_RS05845	COG2204	response regulator
EI427_RS05850	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EI427_RS05860	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EI427_RS05875	COG0649	NAD binding
EI427_RS05930	COG0386	Belongs to the glutathione peroxidase family
EI427_RS05940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EI427_RS05950	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EI427_RS05950	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EI427_RS05955	COG0038	chloride channel
EI427_RS05970	COG0778	Nitroreductase
EI427_RS05975	COG3118	belongs to the thioredoxin family
EI427_RS05985	COG0217	transcriptional regulatory protein
EI427_RS05990	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EI427_RS06005	COG1393	Belongs to the ArsC family
EI427_RS06010	COG1703	isobutyryl-CoA mutase activity
EI427_RS06015	COG0346	lactoylglutathione lyase activity
EI427_RS06020	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EI427_RS06035	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EI427_RS06040	COG0427	acetyl-CoA hydrolase
EI427_RS06045	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EI427_RS06050	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EI427_RS06050	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EI427_RS06055	COG2382	esterase
EI427_RS06065	COG1629	transport
EI427_RS06065	COG4206	TonB-dependent receptor
EI427_RS06075	COG1629	transport
EI427_RS06075	COG4206	TonB-dependent receptor
EI427_RS06085	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EI427_RS06095	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EI427_RS06115	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EI427_RS06120	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
EI427_RS06130	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EI427_RS06160	COG0424	maF-like protein
EI427_RS06175	COG0564	pseudouridine synthase activity
EI427_RS06215	COG0523	cobalamin synthesis protein
EI427_RS06220	COG0360	Binds together with S18 to 16S ribosomal RNA
EI427_RS06225	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EI427_RS06230	COG0359	binds to the 23S rRNA
EI427_RS06255	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EI427_RS06270	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EI427_RS06285	COG1346	cytolysis
EI427_RS06290	COG1380	Effector of murein hydrolase LrgA
EI427_RS06305	COG0513	Belongs to the DEAD box helicase family
EI427_RS06310	COG2259	Doxx family
EI427_RS06315	COG1629	transport
EI427_RS06315	COG4771	TonB-dependent receptor
EI427_RS06320	COG3046	protein related to deoxyribodipyrimidine photolyase
EI427_RS06325	COG0415	Belongs to the DNA photolyase family
EI427_RS06335	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EI427_RS06340	COG0280	phosphate acetyltransferase
EI427_RS06340	COG0857	belongs to the CobB CobQ family
EI427_RS06345	COG0251	oxidation-reduction process
EI427_RS06365	COG0527	aspartate kinase activity
EI427_RS06375	COG1522	sequence-specific DNA binding
EI427_RS06385	COG3292	Two component regulator propeller
EI427_RS06385	COG0745	RESPONSE REGULATOR receiver
EI427_RS06385	COG2205	protein histidine kinase activity
EI427_RS06390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EI427_RS06395	COG0148	phosphopyruvate hydratase activity
EI427_RS06430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EI427_RS06450	COG1629	transport
EI427_RS06450	COG4206	TonB-dependent receptor
EI427_RS06460	COG1629	transport
EI427_RS06470	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EI427_RS06475	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EI427_RS06480	COG0527	aspartate kinase activity
EI427_RS06490	COG1803	Methylglyoxal synthase
EI427_RS06505	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EI427_RS06525	COG1132	(ABC) transporter
EI427_RS06575	COG1216	Glycosyl transferase, family 2
EI427_RS06590	COG0367	asparagine synthase
EI427_RS06615	COG1216	Glycosyl transferase, family 2
EI427_RS06615	COG0463	Glycosyl transferase, family 2
EI427_RS06655	COG1570	exodeoxyribonuclease VII activity
EI427_RS06660	COG1722	exodeoxyribonuclease VII activity
EI427_RS06670	COG3657	addiction module killer protein
EI427_RS06685	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EI427_RS06695	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EI427_RS06720	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EI427_RS06720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EI427_RS06770	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EI427_RS06770	COG0758	DNA mediated transformation
EI427_RS06775	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EI427_RS06795	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EI427_RS06820	COG0813	purine-nucleoside phosphorylase activity
EI427_RS06825	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EI427_RS06830	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EI427_RS06835	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EI427_RS06840	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EI427_RS06850	COG4948	Mandelate Racemase Muconate Lactonizing
EI427_RS06865	COG4864	UPF0365 protein
EI427_RS06870	COG0826	peptidase U32
EI427_RS06880	COG0823	Involved in the tonB-independent uptake of proteins
EI427_RS06880	COG1506	peptidase
EI427_RS06890	COG2195	Cleaves the N-terminal amino acid of tripeptides
EI427_RS06895	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EI427_RS06900	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EI427_RS06905	COG0602	queuosine metabolic process
EI427_RS06910	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EI427_RS06925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EI427_RS06930	COG1183	phosphatidylcholine synthase activity
EI427_RS06945	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EI427_RS06960	COG0124	histidyl-tRNA synthetase
EI427_RS06965	COG1363	Peptidase, m42
EI427_RS06990	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EI427_RS07000	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EI427_RS07005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EI427_RS07010	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EI427_RS07015	COG0511	ligase activity, forming carbon-carbon bonds
EI427_RS07020	COG0439	Biotin carboxylase
EI427_RS07040	COG1760	l-serine dehydratase
EI427_RS07050	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EI427_RS07055	COG0589	response to stress
EI427_RS07075	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EI427_RS07080	COG0513	Belongs to the DEAD box helicase family
EI427_RS07085	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EI427_RS07095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EI427_RS07100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EI427_RS07105	COG0179	Fumarylacetoacetate (FAA) hydrolase
EI427_RS07120	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EI427_RS07140	COG1560	Kdo2-lipid A biosynthetic process
EI427_RS07145	COG0187	DNA topoisomerase II activity
EI427_RS07160	COG2885	chlorophyll binding
EI427_RS07170	COG1024	Enoyl-CoA hydratase
EI427_RS07180	COG0756	dUTP diphosphatase activity
EI427_RS07185	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EI427_RS07200	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EI427_RS07210	COG3186	Phenylalanine-4-hydroxylase
EI427_RS07220	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EI427_RS07220	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EI427_RS07230	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EI427_RS07235	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EI427_RS07240	COG0039	L-malate dehydrogenase activity
EI427_RS07250	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EI427_RS07260	COG2884	Cell division ATP-binding protein ftsE
EI427_RS07285	COG1754	DNA topoisomerase type I activity
EI427_RS07285	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EI427_RS07290	COG0045	succinate-CoA ligase (ADP-forming) activity
EI427_RS07295	COG1663	tetraacyldisaccharide 4'-kinase activity
EI427_RS07315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EI427_RS07320	COG0788	formyltetrahydrofolate deformylase activity
EI427_RS07330	COG1137	ATPase activity
EI427_RS07340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EI427_RS07375	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EI427_RS07380	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EI427_RS07385	COG0537	adenosine 5'-monophosphoramidase activity
EI427_RS07390	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EI427_RS07405	COG0156	8-amino-7-oxononanoate synthase activity
EI427_RS07425	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EI427_RS07430	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EI427_RS07430	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EI427_RS07440	COG0501	Belongs to the peptidase M48B family
EI427_RS07445	COG0305	Participates in initiation and elongation during chromosome replication
EI427_RS07450	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EI427_RS07455	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EI427_RS07460	COG0569	domain protein
EI427_RS07470	COG0791	NLP P60 protein
EI427_RS07480	COG0531	amino acid
EI427_RS07490	COG4399	Belongs to the UPF0754 family
EI427_RS07500	COG1228	amidohydrolase
EI427_RS07520	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EI427_RS07520	COG0047	phosphoribosylformylglycinamidine synthase activity
EI427_RS07535	COG0616	signal peptide processing
EI427_RS07565	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EI427_RS07585	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EI427_RS07600	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EI427_RS07605	COG2239	Acts as a magnesium transporter
EI427_RS07645	COG0793	Belongs to the peptidase S41A family
EI427_RS07665	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EI427_RS07670	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EI427_RS07675	COG0180	Tryptophanyl-tRNA synthetase
EI427_RS07690	COG3537	Alpha-1,2-mannosidase
EI427_RS07695	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EI427_RS07700	COG3537	Alpha-1,2-mannosidase
EI427_RS07705	COG1446	asparaginase
EI427_RS07710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EI427_RS07725	COG0848	biopolymer transport protein
EI427_RS07730	COG0811	peptide transport
EI427_RS07750	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EI427_RS07755	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EI427_RS07770	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EI427_RS07800	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EI427_RS07810	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EI427_RS07815	COG2224	Isocitrate lyase
EI427_RS07825	COG0488	(ABC) transporter
EI427_RS07835	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EI427_RS07840	COG1696	Membrane protein involved in D-alanine export
EI427_RS07900	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EI427_RS07910	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EI427_RS07915	COG0167	dihydroorotate dehydrogenase activity
EI427_RS07925	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EI427_RS07940	COG1028	Short-chain dehydrogenase reductase Sdr
EI427_RS07975	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EI427_RS08000	COG1120	ATPase activity
EI427_RS08005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EI427_RS08010	COG0546	phosphoglycolate phosphatase activity
EI427_RS08015	COG2366	antibiotic biosynthetic process
EI427_RS08025	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EI427_RS08030	COG5000	phosphorelay sensor kinase activity
EI427_RS08040	COG2322	membrane
EI427_RS08045	COG1999	signal sequence binding
EI427_RS08055	COG1845	cytochrome c oxidase, subunit III
EI427_RS08065	COG0109	protoheme IX farnesyltransferase activity
EI427_RS08070	COG1612	heme a metabolic process
EI427_RS08080	COG0037	tRNA processing
EI427_RS08090	COG1575	Belongs to the MenA family. Type 1 subfamily
EI427_RS08095	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EI427_RS08135	COG1640	4-alpha-glucanotransferase
EI427_RS08145	COG2217	Heavy metal translocating P-type atpase
EI427_RS08155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EI427_RS08165	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EI427_RS08180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EI427_RS08190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EI427_RS08210	COG0471	metal ion transport
EI427_RS08240	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
EI427_RS08250	COG0697	spore germination
EI427_RS08275	COG2081	HI0933 family
EI427_RS08315	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EI427_RS08315	COG0617	tRNA 3'-terminal CCA addition
EI427_RS08315	COG0517	IMP dehydrogenase activity
EI427_RS08320	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EI427_RS08355	COG0019	diaminopimelate decarboxylase activity
EI427_RS08365	COG0495	leucyl-tRNA aminoacylation
EI427_RS08380	COG1051	belongs to the nudix hydrolase family
EI427_RS08385	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EI427_RS08390	COG0540	Belongs to the ATCase OTCase family
EI427_RS08395	COG3279	Response regulator of the LytR AlgR family
EI427_RS08430	COG0628	permease
EI427_RS08445	COG2311	Membrane
EI427_RS08470	COG0667	Aldo Keto reductase
EI427_RS08485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EI427_RS08490	COG1131	(ABC) transporter
EI427_RS08495	COG1131	(ABC) transporter
EI427_RS08500	COG0842	Transport permease protein
EI427_RS08505	COG0842	Transport permease protein
EI427_RS08520	COG1595	DNA-templated transcription, initiation
EI427_RS08525	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EI427_RS08540	COG0405	Gamma-glutamyltransferase
EI427_RS08565	COG1250	3-hydroxyacyl-CoA dehydrogenase
EI427_RS08570	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EI427_RS08575	COG0385	Bile acid
EI427_RS08615	COG2755	lipolytic protein G-D-S-L family
EI427_RS08615	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EI427_RS08620	COG3119	arylsulfatase activity
EI427_RS08650	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EI427_RS08660	COG1505	serine-type exopeptidase activity
EI427_RS08710	COG4771	TonB-dependent receptor
EI427_RS08715	COG0702	epimerase
EI427_RS08725	COG1404	Belongs to the peptidase S8 family
EI427_RS08730	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EI427_RS08755	COG4145	pantothenate transmembrane transporter activity
EI427_RS08760	COG1595	DNA-templated transcription, initiation
EI427_RS08800	COG3876	Protein conserved in bacteria
EI427_RS08805	COG1472	Belongs to the glycosyl hydrolase 3 family
EI427_RS08825	COG0719	Fe-S assembly protein
EI427_RS08830	COG0396	ATPase activity
EI427_RS08840	COG3781	membrane
EI427_RS08850	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EI427_RS08855	COG0242	peptide deformylase activity
EI427_RS08865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EI427_RS08880	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EI427_RS08890	COG0297	glycogen (starch) synthase activity
EI427_RS08895	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EI427_RS08910	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EI427_RS08925	COG5002	protein histidine kinase activity
EI427_RS08925	COG2198	Histidine kinase
EI427_RS08925	COG0784	Response regulator, receiver
EI427_RS08930	COG1007	ATP synthesis coupled electron transport
EI427_RS08940	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EI427_RS08945	COG0713	ATP synthesis coupled electron transport
EI427_RS08965	COG2124	cytochrome p450
EI427_RS08975	COG1228	amidohydrolase
EI427_RS08980	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EI427_RS08985	COG2986	histidine ammonia-lyase
EI427_RS09005	COG2197	response regulator
EI427_RS09010	COG0738	Major facilitator superfamily
EI427_RS09065	COG2181	nitrate reductase activity
EI427_RS09065	COG0247	lactate metabolic process
EI427_RS09070	COG0247	lactate metabolic process
EI427_RS09070	COG2181	nitrate reductase activity
EI427_RS09080	COG3340	Belongs to the peptidase S51 family
EI427_RS09085	COG0484	heat shock protein binding
EI427_RS09100	COG3604	Transcriptional regulator
EI427_RS09120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EI427_RS09125	COG0508	dehydrogenase complex catalyzes the overall conversion of
EI427_RS09135	COG0567	Dehydrogenase, E1 component
EI427_RS09145	COG0792	nuclease activity
EI427_RS09155	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EI427_RS09175	COG2211	Major facilitator Superfamily
EI427_RS09185	COG0859	PFAM glycosyl transferase family 9
EI427_RS09195	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EI427_RS09215	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EI427_RS09215	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EI427_RS09250	COG1842	Phage shock protein A
EI427_RS09270	COG0842	Transport permease protein
EI427_RS09270	COG1716	ATPase activity
EI427_RS09270	COG1131	(ABC) transporter
EI427_RS09285	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EI427_RS09290	COG4206	TonB-dependent receptor
EI427_RS09290	COG1629	transport
EI427_RS09295	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EI427_RS09300	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EI427_RS09340	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EI427_RS09355	COG4106	trans-aconitate 2-methyltransferase activity
EI427_RS09360	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EI427_RS09365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EI427_RS09375	COG1218	3'(2'),5'-bisphosphate nucleotidase
EI427_RS09380	COG3781	membrane
EI427_RS09390	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EI427_RS09405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EI427_RS09405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EI427_RS09415	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EI427_RS09420	COG0459	protein refolding
EI427_RS09440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EI427_RS09445	COG0706	membrane insertase activity
EI427_RS09450	COG0504	CTP synthase activity
EI427_RS09480	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EI427_RS09505	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EI427_RS09540	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EI427_RS09545	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EI427_RS09550	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EI427_RS09555	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EI427_RS09570	COG0632	four-way junction helicase activity
EI427_RS09600	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EI427_RS09610	COG0010	Belongs to the arginase family
EI427_RS09640	COG0183	Belongs to the thiolase family
EI427_RS09650	COG4585	Histidine kinase
EI427_RS09665	COG1289	transmembrane transporter activity
EI427_RS09670	COG1882	Formate acetyltransferase
EI427_RS09675	COG2116	formate transmembrane transporter activity
EI427_RS09690	COG0534	Mate efflux family protein
EI427_RS09710	COG2205	protein histidine kinase activity
EI427_RS09740	COG1595	DNA-templated transcription, initiation
EI427_RS09765	COG0745	RESPONSE REGULATOR receiver
EI427_RS09770	COG5002	protein histidine kinase activity
EI427_RS09775	COG0564	pseudouridine synthase activity
EI427_RS09790	COG3584	3D domain protein
EI427_RS09790	COG1388	LysM domain
EI427_RS09795	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EI427_RS09800	COG1454	alcohol dehydrogenase
EI427_RS09815	COG0493	'glutamate synthase
EI427_RS09820	COG0070	glutamate synthase
EI427_RS09820	COG0069	glutamate synthase activity
EI427_RS09820	COG0067	glutamate synthase
EI427_RS09825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EI427_RS09830	COG0037	tRNA processing
EI427_RS09850	COG2319	Wd-40 repeat
EI427_RS09850	COG4249	Peptidase C14 caspase catalytic subunit p20
EI427_RS09860	COG0656	L-ascorbic acid biosynthetic process
EI427_RS09865	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EI427_RS09870	COG0516	GMP reductase activity
EI427_RS09870	COG0517	IMP dehydrogenase activity
EI427_RS09915	COG0579	oxidoreductase
EI427_RS09920	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EI427_RS09925	COG1115	amino acid carrier protein
EI427_RS09940	COG1193	negative regulation of DNA recombination
EI427_RS09950	COG2171	N-acyltransferase activity
EI427_RS09960	COG1649	PFAM Uncharacterised BCR, COG1649
EI427_RS09980	COG2210	Belongs to the sulfur carrier protein TusA family
EI427_RS09995	COG0604	alcohol dehydrogenase
EI427_RS10025	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EI427_RS10035	COG0525	valine-tRNA ligase activity
EI427_RS10060	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EI427_RS10065	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EI427_RS10080	COG0107	imidazoleglycerol-phosphate synthase activity
EI427_RS10085	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EI427_RS10095	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EI427_RS10095	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EI427_RS10110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EI427_RS10115	COG2315	Protein conserved in bacteria
EI427_RS10125	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EI427_RS10130	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EI427_RS10160	COG0842	Transport permease protein
EI427_RS10160	COG1131	(ABC) transporter
EI427_RS10160	COG1716	ATPase activity
EI427_RS10175	COG1605	Chorismate mutase
EI427_RS10175	COG0077	Prephenate dehydratase
EI427_RS10195	COG0784	Response regulator, receiver
EI427_RS10195	COG2205	protein histidine kinase activity
EI427_RS10200	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EI427_RS10215	COG2895	sulfate adenylyltransferase (ATP) activity
EI427_RS10220	COG0175	sulfate reduction
EI427_RS10225	COG0529	Catalyzes the synthesis of activated sulfate
EI427_RS10235	COG0745	RESPONSE REGULATOR receiver
EI427_RS10235	COG4191	Histidine kinase
EI427_RS10235	COG2205	protein histidine kinase activity
EI427_RS10240	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EI427_RS10245	COG0668	transmembrane transport
EI427_RS10250	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EI427_RS10265	COG0303	'Molybdopterin
EI427_RS10275	COG0315	cyclic pyranopterin monophosphate synthase activity
EI427_RS10275	COG0746	molybdenum cofactor guanylyltransferase activity
EI427_RS10305	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EI427_RS10320	COG4585	Histidine kinase
EI427_RS10325	COG2197	response regulator
EI427_RS10330	COG0243	molybdopterin cofactor binding
EI427_RS10340	COG0314	molybdopterin synthase activity
EI427_RS10350	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EI427_RS10355	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EI427_RS10365	COG1805	sodium ion transport
EI427_RS10370	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EI427_RS10405	COG0243	molybdopterin cofactor binding
EI427_RS10420	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EI427_RS10435	COG1074	ATP-dependent DNA helicase activity
EI427_RS10440	COG3279	Response regulator of the LytR AlgR family
EI427_RS10445	COG0501	Belongs to the peptidase M48B family
EI427_RS10450	COG1959	2 iron, 2 sulfur cluster binding
EI427_RS10475	COG2205	protein histidine kinase activity
EI427_RS10475	COG2198	Histidine kinase
EI427_RS10475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EI427_RS10475	COG0784	Response regulator, receiver
EI427_RS10485	COG0166	Belongs to the GPI family
EI427_RS10520	COG0116	Belongs to the methyltransferase superfamily
EI427_RS10540	COG0497	DNA recombination
EI427_RS10550	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EI427_RS10555	COG1366	Belongs to the anti-sigma-factor antagonist family
EI427_RS10560	COG1234	tRNA 3'-trailer cleavage
EI427_RS10575	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EI427_RS10580	COG1322	Protein conserved in bacteria
EI427_RS10585	COG4106	trans-aconitate 2-methyltransferase activity
EI427_RS10610	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EI427_RS10615	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EI427_RS10620	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EI427_RS10625	COG0772	Belongs to the SEDS family
EI427_RS10640	COG1858	cytochrome C peroxidase
EI427_RS10645	COG2824	Alkylphosphonate utilization operon protein PhnA
EI427_RS10660	COG1705	Flagellar rod assembly protein muramidase FlgJ
EI427_RS10660	COG1388	LysM domain
EI427_RS10680	COG0784	Response regulator, receiver
EI427_RS10680	COG2205	protein histidine kinase activity
EI427_RS10690	COG1032	radical SAM domain protein
EI427_RS10710	COG3682	Transcriptional regulator
EI427_RS10725	COG4682	membrane
EI427_RS10795	COG3022	response to hydroperoxide
EI427_RS10800	COG1054	Belongs to the UPF0176 family
EI427_RS10815	COG2201	protein-glutamate methylesterase activity
EI427_RS10825	COG0719	Fe-S assembly protein
EI427_RS10835	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EI427_RS10855	COG2205	protein histidine kinase activity
EI427_RS10855	COG0745	RESPONSE REGULATOR receiver
EI427_RS10855	COG3292	Two component regulator propeller
EI427_RS10880	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EI427_RS10895	COG1472	Belongs to the glycosyl hydrolase 3 family
EI427_RS10900	COG1554	hydrolase, family 65, central catalytic
EI427_RS10905	COG0702	epimerase
EI427_RS10910	COG4771	TonB-dependent receptor
EI427_RS10915	COG1546	Belongs to the CinA family
EI427_RS10915	COG1058	Belongs to the CinA family
EI427_RS10920	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EI427_RS10935	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EI427_RS10940	COG1803	Methylglyoxal synthase
EI427_RS10940	COG1597	lipid kinase activity
EI427_RS11050	COG0445	tRNA wobble uridine modification
EI427_RS11060	COG3119	arylsulfatase activity
EI427_RS11095	COG1028	Short-chain dehydrogenase reductase Sdr
EI427_RS11100	COG2271	Major facilitator Superfamily
EI427_RS11120	COG0702	epimerase
EI427_RS11125	COG1629	transport
EI427_RS11130	COG2186	Transcriptional regulator
EI427_RS11135	COG0006	proline dipeptidase activity
EI427_RS11160	COG1073	alpha beta
EI427_RS11165	COG0824	Thioesterase
EI427_RS11180	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EI427_RS11190	COG1242	4 iron, 4 sulfur cluster binding
EI427_RS11195	COG0484	heat shock protein binding
EI427_RS11200	COG3781	membrane
EI427_RS11215	COG3119	arylsulfatase activity
EI427_RS11225	COG1725	Transcriptional regulator
EI427_RS11235	COG1131	(ABC) transporter
EI427_RS11270	COG0408	coproporphyrinogen oxidase activity
EI427_RS11280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EI427_RS11285	COG0534	Mate efflux family protein
EI427_RS11290	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EI427_RS11315	COG0343	queuine tRNA-ribosyltransferase activity
EI427_RS11360	COG1561	YicC-like family, N-terminal region
EI427_RS11365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EI427_RS11375	COG0415	Belongs to the DNA photolyase family
EI427_RS11385	COG2177	Part of the ABC transporter FtsEX involved in
EI427_RS11390	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EI427_RS11400	COG1272	protein, Hemolysin III
EI427_RS11410	COG0420	3'-5' exonuclease activity
EI427_RS11485	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EI427_RS11490	COG1674	ftsk spoiiie
EI427_RS11505	COG1482	cell wall glycoprotein biosynthetic process
EI427_RS11560	COG2949	membrane
EI427_RS11575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EI427_RS11580	COG2249	NAD(P)H dehydrogenase (quinone) activity
EI427_RS11600	COG1846	Transcriptional regulator
EI427_RS11615	COG1278	Cold shock
EI427_RS11630	COG0483	inositol monophosphate 1-phosphatase activity
EI427_RS11640	COG0366	Alpha amylase catalytic
EI427_RS11685	COG0017	Asparaginyl-tRNA synthetase
EI427_RS11695	COG1136	(ABC) transporter
EI427_RS11695	COG0577	efflux transmembrane transporter activity
EI427_RS11715	COG4771	TonB-dependent receptor
EI427_RS11720	COG2314	TM2 domain
EI427_RS11735	COG1053	succinate dehydrogenase
EI427_RS11745	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EI427_RS11765	COG0714	Associated with various cellular activities
EI427_RS11770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EI427_RS11780	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EI427_RS11785	COG1012	belongs to the aldehyde dehydrogenase family
EI427_RS11790	COG3279	Response regulator of the LytR AlgR family
EI427_RS11800	COG0512	Glutamine amidotransferase of anthranilate synthase
EI427_RS11810	COG1610	YqeY-like protein
EI427_RS11815	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EI427_RS11820	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EI427_RS11825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EI427_RS11830	COG0492	ferredoxin-NADP+ reductase activity
EI427_RS11835	COG0739	heme binding
EI427_RS11845	COG0004	ammonium transporteR
EI427_RS11850	COG0259	pyridoxamine-phosphate oxidase activity
EI427_RS11855	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EI427_RS11870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EI427_RS11880	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EI427_RS11885	COG3604	Transcriptional regulator
EI427_RS11905	COG2153	protein acetylation
EI427_RS11915	COG0105	UTP biosynthetic process
EI427_RS11920	COG1132	(ABC) transporter
EI427_RS11925	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EI427_RS11935	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EI427_RS11940	COG3005	denitrification pathway
EI427_RS11945	COG2719	SpoVR family
EI427_RS11950	COG2718	Belongs to the UPF0229 family
EI427_RS11955	COG2766	serine protein kinase
EI427_RS11975	COG2252	PERMEase
EI427_RS11980	COG2197	response regulator
EI427_RS11985	COG2197	response regulator
EI427_RS12015	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EI427_RS12040	COG1388	LysM domain
EI427_RS12040	COG3942	CHAP domain
EI427_RS12050	COG1030	water channel activity
EI427_RS12055	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EI427_RS12060	COG1595	DNA-templated transcription, initiation
EI427_RS12065	COG1011	Hydrolase
EI427_RS12080	COG0346	lactoylglutathione lyase activity
EI427_RS12095	COG0577	efflux transmembrane transporter activity
EI427_RS12095	COG1136	(ABC) transporter
EI427_RS12125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EI427_RS12130	COG5002	protein histidine kinase activity
EI427_RS12135	COG0275	rRNA processing
EI427_RS12165	COG0745	RESPONSE REGULATOR receiver
EI427_RS12165	COG2972	Histidine kinase
EI427_RS12170	COG1703	isobutyryl-CoA mutase activity
EI427_RS12170	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EI427_RS12170	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EI427_RS12200	COG0175	sulfate reduction
EI427_RS12235	COG0439	Biotin carboxylase
EI427_RS12250	COG1196	nuclear chromosome segregation
EI427_RS12260	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EI427_RS12265	COG2086	electron transfer activity
EI427_RS12270	COG1528	Iron-storage protein
EI427_RS12275	COG1335	isochorismatase
EI427_RS12280	COG1363	Peptidase, m42
EI427_RS12330	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EI427_RS12350	COG0157	Belongs to the NadC ModD family
EI427_RS12365	COG2050	protein possibly involved in aromatic compounds catabolism
EI427_RS12375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EI427_RS12405	COG1091	dTDP-4-dehydrorhamnose reductase activity
EI427_RS12415	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EI427_RS12420	COG0805	protein transport
EI427_RS12425	COG0860	N-Acetylmuramoyl-L-alanine amidase
EI427_RS12450	COG0367	asparagine synthase
EI427_RS12465	COG0564	pseudouridine synthase activity
EI427_RS12505	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EI427_RS12510	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EI427_RS12515	COG0440	acetolactate synthase activity
EI427_RS12520	COG0028	Belongs to the TPP enzyme family
EI427_RS12525	COG0129	dihydroxy-acid dehydratase activity
EI427_RS12535	COG0726	polysaccharide deacetylase
EI427_RS12540	COG1192	Involved in chromosome partitioning
EI427_RS12545	COG1475	DNA binding
EI427_RS12555	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EI427_RS12560	COG0681	Belongs to the peptidase S26 family
EI427_RS12565	COG4717	serine-type aminopeptidase activity
EI427_RS12570	COG1705	Flagellar rod assembly protein muramidase FlgJ
EI427_RS12580	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EI427_RS12590	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EI427_RS12595	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EI427_RS12610	COG0457	Tetratricopeptide repeat
EI427_RS12640	COG5002	protein histidine kinase activity
EI427_RS12670	COG0583	DNA-binding transcription factor activity
EI427_RS12675	COG2855	membrane
EI427_RS12690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EI427_RS12695	COG0326	Molecular chaperone. Has ATPase activity
EI427_RS12700	COG0513	Belongs to the DEAD box helicase family
EI427_RS12705	COG4585	Histidine kinase
EI427_RS12710	COG2197	response regulator
EI427_RS12725	COG0126	phosphoglycerate kinase activity
EI427_RS12745	COG1477	protein flavinylation
EI427_RS12750	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
EI427_RS12770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EI427_RS12775	COG2223	nitrite transmembrane transporter activity
EI427_RS12790	COG0653	protein targeting
EI427_RS12825	COG2312	Erythromycin esterase
EI427_RS12850	COG2070	2-Nitropropane dioxygenase
EI427_RS12850	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EI427_RS12855	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EI427_RS12855	COG3321	synthase
EI427_RS12855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EI427_RS12860	COG0604	alcohol dehydrogenase
EI427_RS12860	COG3321	synthase
EI427_RS12865	COG0415	Belongs to the DNA photolyase family
EI427_RS12900	COG4771	TonB-dependent receptor
EI427_RS12915	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EI427_RS13000	COG3344	reverse transcriptase
EI427_RS13015	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EI427_RS13055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EI427_RS13060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EI427_RS13065	COG0571	ribonuclease III activity
EI427_RS13100	COG1739	Uncharacterized protein family UPF0029
EI427_RS13135	COG0481	GTPase activity
EI427_RS13165	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EI427_RS13170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EI427_RS13185	COG2890	protein-(glutamine-N5) methyltransferase activity
EI427_RS13190	COG2304	oxidoreductase activity
EI427_RS13210	COG1368	sulfuric ester hydrolase activity
EI427_RS13215	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EI427_RS13220	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EI427_RS13225	COG2183	response to ionizing radiation
EI427_RS13230	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EI427_RS13240	COG0233	cytoplasmic translational termination
EI427_RS13245	COG0528	UMP kinase activity
EI427_RS13265	COG2197	response regulator
EI427_RS13275	COG3341	Caulimovirus viroplasmin
EI427_RS13275	COG0328	RNA-DNA hybrid ribonuclease activity
EI427_RS13305	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EI427_RS13320	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EI427_RS13325	COG4251	negative regulation of phosphorylation
EI427_RS13330	COG0784	Response regulator, receiver
EI427_RS13335	COG0784	Response regulator, receiver
EI427_RS13335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EI427_RS13335	COG2205	protein histidine kinase activity
EI427_RS13335	COG2198	Histidine kinase
EI427_RS13340	COG0745	RESPONSE REGULATOR receiver
EI427_RS13365	COG0339	signal peptide processing
EI427_RS13370	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EI427_RS13380	COG2267	carboxylic ester hydrolase activity
EI427_RS13400	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EI427_RS13415	COG1515	deoxyribonuclease V activity
EI427_RS13420	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EI427_RS13425	COG0612	Peptidase, M16
EI427_RS13470	COG0006	proline dipeptidase activity
EI427_RS13480	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EI427_RS13485	COG0489	protein tyrosine kinase activity
EI427_RS13495	COG0366	Alpha amylase catalytic
EI427_RS13500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EI427_RS13525	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EI427_RS13550	COG1138	Cytochrome C-type biogenesis protein
EI427_RS13600	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EI427_RS13610	COG4953	penicillin-binding protein 1C
EI427_RS13615	COG0025	NhaP-type Na H and K H
EI427_RS13620	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EI427_RS13665	COG0437	4 iron, 4 sulfur cluster binding
EI427_RS13680	COG1607	acyl-coa hydrolase
EI427_RS13685	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EI427_RS13690	COG1047	Peptidyl-prolyl cis-trans
EI427_RS13700	COG1570	exodeoxyribonuclease VII activity
EI427_RS13710	COG0280	phosphate acetyltransferase
EI427_RS13730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EI427_RS13735	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EI427_RS13750	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EI427_RS13750	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EI427_RS13755	COG2363	Small membrane protein
EI427_RS13760	COG2070	2-Nitropropane dioxygenase
EI427_RS13765	COG1131	(ABC) transporter
EI427_RS13785	COG3119	arylsulfatase activity
EI427_RS13790	COG4977	sequence-specific DNA binding
EI427_RS13790	COG1917	Cupin 2, conserved barrel domain protein
EI427_RS13825	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EI427_RS13840	COG0019	diaminopimelate decarboxylase activity
EI427_RS13865	COG1028	Short-chain dehydrogenase reductase Sdr
EI427_RS13870	COG0010	Belongs to the arginase family
EI427_RS13915	COG2972	Histidine kinase
EI427_RS13920	COG3279	Response regulator of the LytR AlgR family
EI427_RS13945	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EI427_RS13950	COG0302	gtp cyclohydrolase
EI427_RS13960	COG2801	Transposase and inactivated derivatives
EI427_RS13985	COG3177	Filamentation induced by cAMP protein fic
EI427_RS14010	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EI427_RS14025	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EI427_RS14030	COG0363	glucosamine-6-phosphate deaminase activity
EI427_RS14035	COG3876	Protein conserved in bacteria
EI427_RS14065	COG0193	aminoacyl-tRNA hydrolase activity
EI427_RS14075	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EI427_RS14105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EI427_RS14115	COG0745	RESPONSE REGULATOR receiver
EI427_RS14115	COG2205	protein histidine kinase activity
EI427_RS14115	COG3292	Two component regulator propeller
EI427_RS14115	COG3292	Two component regulator propeller
EI427_RS14115	COG2205	protein histidine kinase activity
EI427_RS14115	COG0745	RESPONSE REGULATOR receiver
EI427_RS14145	COG1301	dicarboxylic acid transport
EI427_RS14155	COG3842	ATPase activity
EI427_RS14160	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EI427_RS14165	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EI427_RS14165	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EI427_RS14170	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EI427_RS14175	COG1078	dGTPase activity
EI427_RS14190	COG0442	prolyl-tRNA aminoacylation
EI427_RS14200	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EI427_RS14210	COG0268	Binds directly to 16S ribosomal RNA
EI427_RS14215	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EI427_RS14220	COG0730	response to heat
EI427_RS14230	COG1283	sodium-dependent phosphate transmembrane transporter activity
EI427_RS14235	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EI427_RS14240	COG2234	aminopeptidase activity
EI427_RS14255	COG0423	glycine-tRNA ligase activity
EI427_RS14260	COG0733	neurotransmitter:sodium symporter activity
EI427_RS14265	COG0733	neurotransmitter:sodium symporter activity
EI427_RS14270	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EI427_RS14275	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EI427_RS14280	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EI427_RS14285	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EI427_RS14290	COG0089	rRNA binding
EI427_RS14295	COG0088	Forms part of the polypeptide exit tunnel
EI427_RS14300	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EI427_RS14305	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EI427_RS14320	COG0698	ribose 5-phosphate isomerase
EI427_RS14355	COG0556	nucleotide-excision repair
EI427_RS14375	COG0248	Ppx GppA phosphatase
EI427_RS14420	COG0250	Participates in transcription elongation, termination and antitermination
EI427_RS14425	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EI427_RS14430	COG0081	regulation of translation
EI427_RS14435	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EI427_RS14440	COG0222	ribosome binding
EI427_RS14460	COG1501	Belongs to the glycosyl hydrolase 31 family
EI427_RS14465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EI427_RS14470	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EI427_RS14495	COG5002	protein histidine kinase activity
EI427_RS14505	COG0826	peptidase U32
EI427_RS14535	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EI427_RS14535	COG3608	succinylglutamate desuccinylase aspartoacylase
EI427_RS14555	COG0668	transmembrane transport
EI427_RS14560	COG0668	transmembrane transport
EI427_RS14565	COG0784	Response regulator, receiver
EI427_RS14565	COG5002	protein histidine kinase activity
EI427_RS14565	COG2198	Histidine kinase
EI427_RS14585	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EI427_RS14595	COG1381	Involved in DNA repair and RecF pathway recombination
EI427_RS14600	COG0358	DNA primase activity
EI427_RS14630	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EI427_RS14640	COG0154	amidase activity
EI427_RS14645	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EI427_RS14650	COG1132	(ABC) transporter
EI427_RS14660	COG2267	carboxylic ester hydrolase activity
EI427_RS14670	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EI427_RS14685	COG0575	Belongs to the CDS family
EI427_RS14700	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EI427_RS14735	COG1702	phosphate starvation-inducible protein PhoH
EI427_RS14750	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EI427_RS14755	COG4974	Belongs to the 'phage' integrase family
EI427_RS14780	COG4591	ABC-type transport system involved in lipoprotein release permease component
EI427_RS14785	COG1473	amidohydrolase
EI427_RS14790	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EI427_RS14795	COG0484	heat shock protein binding
EI427_RS14820	COG1960	acyl-CoA dehydrogenase activity
EI427_RS14825	COG2234	aminopeptidase activity
EI427_RS14830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EI427_RS14845	COG2860	membrane
EI427_RS14865	COG2095	MarC family integral membrane protein
EI427_RS14925	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EI427_RS14935	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EI427_RS14935	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EI427_RS14945	COG0572	uridine kinase
EI427_RS14950	COG0569	domain protein
EI427_RS14955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EI427_RS14990	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EI427_RS15005	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EI427_RS15015	COG0584	glycerophosphoryl diester phosphodiesterase
EI427_RS15060	COG0471	metal ion transport
EI427_RS15060	COG3273	potassium ion transport
EI427_RS15075	COG0730	response to heat
EI427_RS15080	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EI427_RS15095	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EI427_RS15105	COG0351	phosphomethylpyrimidine kinase
EI427_RS15110	COG0352	thiamine-phosphate diphosphorylase activity
EI427_RS15115	COG2022	thiamine diphosphate biosynthetic process
EI427_RS15120	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EI427_RS15135	COG0463	Glycosyl transferase, family 2
EI427_RS15140	COG0562	UDP-galactopyranose mutase
EI427_RS15185	COG1132	(ABC) transporter
EI427_RS15190	COG0702	epimerase
EI427_RS15220	COG0183	Belongs to the thiolase family
EI427_RS15225	COG1250	3-hydroxyacyl-CoA dehydrogenase
EI427_RS15225	COG1024	Enoyl-CoA hydratase
EI427_RS15235	COG1132	(ABC) transporter
EI427_RS15245	COG0563	adenylate kinase activity
EI427_RS15250	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EI427_RS15255	COG0783	Belongs to the Dps family
EI427_RS15285	COG2208	phosphoserine phosphatase activity
EI427_RS15290	COG2351	hydroxyisourate hydrolase activity
EI427_RS15300	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EI427_RS15305	COG0670	Belongs to the BI1 family
EI427_RS15330	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EI427_RS15340	COG1012	belongs to the aldehyde dehydrogenase family
EI427_RS15375	COG0482	sulfurtransferase activity
EI427_RS15405	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EI427_RS15410	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EI427_RS15425	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EI427_RS15435	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EI427_RS15465	COG1045	serine acetyltransferase
EI427_RS15470	COG3250	beta-galactosidase activity
EI427_RS15485	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EI427_RS15490	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EI427_RS15495	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EI427_RS15525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EI427_RS15530	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EI427_RS15545	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EI427_RS15610	COG1956	GAF domain-containing protein
EI427_RS15615	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EI427_RS15640	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EI427_RS15645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EI427_RS15655	COG0071	Belongs to the small heat shock protein (HSP20) family
EI427_RS15680	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EI427_RS15685	COG2264	protein methyltransferase activity
EI427_RS15700	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EI427_RS15710	COG1566	PFAM secretion protein HlyD family protein
EI427_RS15720	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EI427_RS15725	COG1694	Mazg nucleotide pyrophosphohydrolase
EI427_RS15730	COG0702	epimerase
EI427_RS15735	COG0714	Associated with various cellular activities
EI427_RS15750	COG2304	oxidoreductase activity
EI427_RS15770	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EI427_RS15775	COG0049	tRNA binding
EI427_RS15780	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EI427_RS15785	COG0051	transcription antitermination factor activity, RNA binding
EI427_RS15805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EI427_RS15820	COG2333	competence protein COMEC
EI427_RS15820	COG0658	competence protein
EI427_RS15825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EI427_RS15830	COG1104	cysteine desulfurase activity
EI427_RS15835	COG0148	phosphopyruvate hydratase activity
EI427_RS15840	COG0438	transferase activity, transferring glycosyl groups
EI427_RS15855	COG1028	Short-chain dehydrogenase reductase Sdr
EI427_RS15865	COG0653	protein targeting
EI427_RS15870	COG0545	Peptidyl-prolyl cis-trans isomerase
EI427_RS15880	COG0545	Peptidyl-prolyl cis-trans isomerase
EI427_RS15885	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EI427_RS15890	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EI427_RS15900	COG0463	Glycosyl transferase, family 2
EI427_RS15915	COG4771	TonB-dependent receptor
EI427_RS15920	COG2972	Histidine kinase
EI427_RS15925	COG3279	Response regulator of the LytR AlgR family
EI427_RS15970	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EI427_RS15980	COG2239	Acts as a magnesium transporter
EI427_RS15990	COG3279	Response regulator of the LytR AlgR family
EI427_RS16000	COG1733	regulation of RNA biosynthetic process
EI427_RS16020	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EI427_RS16025	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EI427_RS16035	COG0606	chelatase, subunit chli
EI427_RS16075	COG1136	(ABC) transporter
EI427_RS16090	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EI427_RS16105	COG2249	NAD(P)H dehydrogenase (quinone) activity
EI427_RS16110	COG3591	Belongs to the peptidase S1B family
EI427_RS16120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EI427_RS16125	COG1185	polyribonucleotide nucleotidyltransferase activity
EI427_RS16130	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EI427_RS16140	COG1757	Na H antiporter
EI427_RS16150	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EI427_RS16155	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EI427_RS16160	COG0066	3-isopropylmalate dehydratase activity
EI427_RS16165	COG0473	3-isopropylmalate dehydrogenase activity
EI427_RS16245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EI427_RS16275	COG4771	TonB-dependent receptor
EI427_RS16280	COG2267	carboxylic ester hydrolase activity
EI427_RS16290	COG1028	Short-chain dehydrogenase reductase Sdr
EI427_RS16300	COG1609	Transcriptional regulator
EI427_RS16305	COG4771	TonB-dependent receptor
EI427_RS16355	COG3119	arylsulfatase activity
EI427_RS16395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EI427_RS16465	COG2207	Transcriptional regulator
EI427_RS16465	COG0662	Cupin 2, conserved barrel domain protein
EI427_RS16530	COG2205	protein histidine kinase activity
EI427_RS16530	COG0745	RESPONSE REGULATOR receiver
EI427_RS16530	COG3292	Two component regulator propeller
EI427_RS16560	COG5434	Belongs to the glycosyl hydrolase 28 family
EI427_RS16565	COG3250	beta-galactosidase activity
EI427_RS16570	COG3119	arylsulfatase activity
EI427_RS16645	COG3119	arylsulfatase activity
EI427_RS16660	COG3119	arylsulfatase activity
EI427_RS16680	COG0300	oxidoreductase activity
EI427_RS16745	COG0433	COG0433 Predicted ATPase
EI427_RS16770	COG2249	NAD(P)H dehydrogenase (quinone) activity
EI427_RS16805	COG0800	Aldolase
EI427_RS16815	COG1012	belongs to the aldehyde dehydrogenase family
EI427_RS16820	COG4948	Mandelate Racemase Muconate Lactonizing
EI427_RS16830	COG3119	arylsulfatase activity
EI427_RS16835	COG3250	beta-galactosidase activity
EI427_RS16845	COG3119	arylsulfatase activity
EI427_RS16865	COG1629	transport
EI427_RS16885	COG0501	Belongs to the peptidase M48B family
EI427_RS16895	COG0667	Aldo Keto reductase
EI427_RS16910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EI427_RS16930	COG0243	molybdopterin cofactor binding
EI427_RS16945	COG0437	4 iron, 4 sulfur cluster binding
EI427_RS16975	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
EI427_RS16980	COG3119	arylsulfatase activity
EI427_RS16995	COG4206	TonB-dependent receptor
EI427_RS16995	COG1629	transport
EI427_RS17010	COG3537	Alpha-1,2-mannosidase
EI427_RS17020	COG2814	Major facilitator Superfamily
EI427_RS17025	COG1940	carbohydrate kinase activity
EI427_RS17030	COG2188	Transcriptional regulator
EI427_RS17035	COG1917	Cupin 2, conserved barrel domain protein
EI427_RS17035	COG2169	Transcriptional regulator
EI427_RS17050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EI427_RS17060	COG0596	Alpha beta hydrolase
EI427_RS17100	COG3507	Belongs to the glycosyl hydrolase 43 family
EI427_RS17105	COG1366	Belongs to the anti-sigma-factor antagonist family
EI427_RS17165	COG0798	PFAM Bile acid sodium symporter
EI427_RS17200	COG0596	Alpha beta hydrolase
EI427_RS17225	COG1192	Involved in chromosome partitioning
EI427_RS17255	COG3119	arylsulfatase activity
EI427_RS17260	COG3119	arylsulfatase activity
EI427_RS17265	COG3119	arylsulfatase activity
EI427_RS17280	COG1629	transport
EI427_RS17300	COG5434	Belongs to the glycosyl hydrolase 28 family
EI427_RS17305	COG1764	response to oxidative stress
EI427_RS17315	COG1846	Transcriptional regulator
EI427_RS17380	COG3119	arylsulfatase activity
EI427_RS17385	COG3250	beta-galactosidase activity
EI427_RS17390	COG3119	arylsulfatase activity
EI427_RS17430	COG1733	regulation of RNA biosynthetic process
EI427_RS17465	COG3250	beta-galactosidase activity
EI427_RS17475	COG3119	arylsulfatase activity
EI427_RS17480	COG5434	Belongs to the glycosyl hydrolase 28 family
EI427_RS17485	COG3292	Two component regulator propeller
EI427_RS17485	COG2205	protein histidine kinase activity
EI427_RS17485	COG0745	RESPONSE REGULATOR receiver
EI427_RS17490	COG5434	Belongs to the glycosyl hydrolase 28 family
EI427_RS17495	COG3119	arylsulfatase activity
EI427_RS17495	COG3408	Glycogen debranching enzyme
EI427_RS17500	COG3119	arylsulfatase activity
EI427_RS17535	COG3119	arylsulfatase activity
EI427_RS17550	COG2207	Transcriptional regulator
EI427_RS17560	COG2205	protein histidine kinase activity
EI427_RS17560	COG3292	Two component regulator propeller
EI427_RS17560	COG0745	RESPONSE REGULATOR receiver
EI427_RS17575	COG0702	epimerase
EI427_RS17580	COG4771	TonB-dependent receptor
EI427_RS17590	COG4124	Belongs to the glycosyl hydrolase 26 family
EI427_RS17600	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
EI427_RS17605	COG2942	2-epimerase
EI427_RS17615	COG3119	arylsulfatase activity
EI427_RS17655	COG3401	FG-GAP repeat protein
EI427_RS17670	COG3250	beta-galactosidase activity
EI427_RS17675	COG3408	Glycogen debranching enzyme
EI427_RS17675	COG3119	arylsulfatase activity
EI427_RS17680	COG3401	FG-GAP repeat protein
EI427_RS17690	COG0702	epimerase
EI427_RS17695	COG4771	TonB-dependent receptor
EI427_RS17700	COG2205	protein histidine kinase activity
EI427_RS17700	COG0745	RESPONSE REGULATOR receiver
EI427_RS17700	COG3292	Two component regulator propeller
EI427_RS17715	COG2207	Transcriptional regulator
EI427_RS17715	COG1917	Cupin 2, conserved barrel domain protein
EI427_RS17730	COG3119	arylsulfatase activity
EI427_RS17735	COG3119	arylsulfatase activity
EI427_RS17745	COG4249	Peptidase C14 caspase catalytic subunit p20
EI427_RS17745	COG2319	Wd-40 repeat
EI427_RS17765	COG1131	(ABC) transporter
EI427_RS17880	COG0477	Major facilitator Superfamily
EI427_RS17930	COG3867	Arabinogalactan endo-beta-1,4-galactanase
EI427_RS17945	COG0653	protein targeting
EI427_RS18010	COG1366	Belongs to the anti-sigma-factor antagonist family
EI427_RS18075	COG3119	arylsulfatase activity
EI427_RS18085	COG3291	Pkd domain containing protein
EI427_RS18090	COG2207	Transcriptional regulator
EI427_RS18090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EI427_RS18130	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EI427_RS18145	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EI427_RS18150	COG1136	(ABC) transporter
EI427_RS18150	COG0577	efflux transmembrane transporter activity
EI427_RS18175	COG1960	acyl-CoA dehydrogenase activity
EI427_RS18180	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EI427_RS18180	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EI427_RS18195	COG0228	four-way junction DNA binding
EI427_RS18210	COG1194	a g-specific adenine glycosylase
EI427_RS18220	COG4535	Mg2 and Co2 transporter CorC
EI427_RS18230	COG0745	RESPONSE REGULATOR receiver
EI427_RS18260	COG0700	Nucleoside recognition
EI427_RS18275	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EI427_RS18280	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EI427_RS18295	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EI427_RS18305	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EI427_RS18355	COG2201	protein-glutamate methylesterase activity
EI427_RS18360	COG0514	ATP-dependent DNA helicase (RecQ)
EI427_RS18365	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EI427_RS18385	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EI427_RS18410	COG3206	protein involved in exopolysaccharide biosynthesis
EI427_RS18410	COG0489	protein tyrosine kinase activity
EI427_RS18430	COG1809	phosphosulfolactate synthase activity
EI427_RS18435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EI427_RS18445	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EI427_RS18455	COG0564	pseudouridine synthase activity
EI427_RS18460	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EI427_RS18465	COG4221	oxidoreductase activity
EI427_RS18470	COG1796	DNA polymerase
EI427_RS18470	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EI427_RS18480	COG0085	RNA polymerase activity
EI427_RS18485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EI427_RS18510	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EI427_RS18525	COG0194	GDP metabolic process
EI427_RS18530	COG1595	DNA-templated transcription, initiation
EI427_RS18540	COG3852	Histidine kinase
EI427_RS18545	COG2204	response regulator
EI427_RS18570	COG1131	(ABC) transporter
EI427_RS18585	COG1136	(ABC) transporter
EI427_RS18605	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EI427_RS18610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EI427_RS18700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EI427_RS18700	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EI427_RS18720	COG0445	tRNA wobble uridine modification
EI427_RS18725	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EI427_RS18740	COG0747	negative chemotaxis
EI427_RS18745	COG0708	Exodeoxyribonuclease III
EI427_RS18755	COG1040	competence protein
EI427_RS18765	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EI427_RS18780	COG1862	Preprotein translocase
EI427_RS18790	COG0237	dephospho-CoA kinase activity
EI427_RS18795	COG0138	bifunctional purine biosynthesis protein purh
EI427_RS18800	COG2154	pterin-4-alpha-carbinolamine dehydratase
EI427_RS18805	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EI427_RS18810	COG0488	(ABC) transporter
EI427_RS18825	COG2373	Large extracellular alpha-helical protein
EI427_RS18835	COG1595	DNA-templated transcription, initiation
EI427_RS18850	COG1595	DNA-templated transcription, initiation
EI427_RS18875	COG2255	four-way junction helicase activity
EI427_RS18895	COG0542	response to heat
EI427_RS18930	COG1115	amino acid carrier protein
EI427_RS18950	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EI427_RS18960	COG3951	Flagellar rod assembly protein muramidase FlgJ
EI427_RS18960	COG1705	Flagellar rod assembly protein muramidase FlgJ
EI427_RS18970	COG1136	(ABC) transporter
EI427_RS18970	COG0577	efflux transmembrane transporter activity
EI427_RS19005	COG0776	regulation of translation
EI427_RS19015	COG1530	ribonuclease E activity
EI427_RS19020	COG3118	belongs to the thioredoxin family
EI427_RS19035	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EI427_RS19045	COG0509	glycine decarboxylation via glycine cleavage system
EI427_RS19100	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EI427_RS19105	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EI427_RS19115	COG0552	protein localization to endoplasmic reticulum
EI427_RS19125	COG0205	6-phosphofructokinase activity
EI427_RS19130	COG0659	secondary active sulfate transmembrane transporter activity
EI427_RS19140	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EI427_RS19145	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EI427_RS19170	COG2819	hydrolase of the alpha beta superfamily
EI427_RS19175	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EI427_RS19180	COG0557	exoribonuclease II activity
EI427_RS19190	COG0295	cytidine deaminase activity
EI427_RS19200	COG1490	D-aminoacyl-tRNA deacylase activity
EI427_RS19220	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EI427_RS19240	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EI427_RS19250	COG0052	Belongs to the universal ribosomal protein uS2 family
EI427_RS19255	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EI427_RS19260	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EI427_RS19270	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EI427_RS19285	COG0254	rRNA binding
EI427_RS19320	COG5492	domain, Protein
EI427_RS19335	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EI427_RS19345	COG2207	Transcriptional regulator
EI427_RS19360	COG2267	carboxylic ester hydrolase activity
EI427_RS19430	COG2095	MarC family integral membrane protein
EI427_RS19440	COG2197	response regulator
EI427_RS19445	COG4585	Histidine kinase
EI427_RS19470	COG0460	homoserine dehydrogenase
EI427_RS19470	COG0527	aspartate kinase activity
EI427_RS19475	COG0083	homoserine kinase activity
EI427_RS19485	COG2197	response regulator
EI427_RS19505	COG1022	Amp-dependent synthetase and ligase
EI427_RS19535	COG2312	Erythromycin esterase
EI427_RS19540	COG1733	regulation of RNA biosynthetic process
EI427_RS19545	COG0778	Nitroreductase
EI427_RS19565	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EI427_RS19595	COG0149	triose-phosphate isomerase activity
EI427_RS19610	COG1228	amidohydrolase
EI427_RS19620	COG1090	epimerase
EI427_RS19625	COG4771	TonB-dependent receptor
EI427_RS19635	COG4771	TonB-dependent receptor
EI427_RS19645	COG4771	TonB-dependent receptor
EI427_RS19655	COG4771	TonB-dependent receptor
EI427_RS19665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EI427_RS19665	COG0519	Catalyzes the synthesis of GMP from XMP
EI427_RS19670	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EI427_RS19675	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EI427_RS19680	COG0181	hydroxymethylbilane synthase activity
EI427_RS19690	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EI427_RS19700	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EI427_RS19710	COG0009	L-threonylcarbamoyladenylate synthase
EI427_RS19715	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EI427_RS19720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EI427_RS19730	COG0321	lipoyl(octanoyl) transferase activity
EI427_RS19740	COG2095	MarC family integral membrane protein
EI427_RS19750	COG0131	Imidazoleglycerol-phosphate dehydratase
EI427_RS19750	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EI427_RS19765	COG0322	excinuclease ABC activity
EI427_RS19775	COG4989	oxidoreductase activity
EI427_RS19810	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EI427_RS19825	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EI427_RS19840	COG0542	response to heat
EI427_RS19850	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EI427_RS19855	COG1192	Involved in chromosome partitioning
EI427_RS19860	COG2954	triphosphatase activity
EI427_RS19865	COG0626	cystathionine gamma-synthase activity
EI427_RS19880	COG1611	Belongs to the LOG family
EI427_RS19885	COG1388	LysM domain
EI427_RS19885	COG0741	lytic transglycosylase activity
EI427_RS19890	COG1160	GTP binding
EI427_RS19905	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EI427_RS19915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EI427_RS19920	COG1940	carbohydrate kinase activity
EI427_RS19930	COG1940	carbohydrate kinase activity
EI427_RS19940	COG4206	TonB-dependent receptor
EI427_RS19940	COG1629	transport
EI427_RS19955	COG0793	Belongs to the peptidase S41A family
EI427_RS19960	COG3264	Mechanosensitive ion channel
EI427_RS19960	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EI427_RS19970	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EI427_RS19980	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EI427_RS19990	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EI427_RS20025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EI427_RS20035	COG1428	Deoxynucleoside kinase
EI427_RS20040	COG1428	Deoxynucleoside kinase
EI427_RS20045	COG0572	uridine kinase
EI427_RS20050	COG1280	lysine exporter protein (LysE YggA)
EI427_RS20055	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EI427_RS20060	COG0594	ribonuclease P activity
EI427_RS20065	COG3951	Flagellar rod assembly protein muramidase FlgJ
EI427_RS20065	COG1705	Flagellar rod assembly protein muramidase FlgJ
EI427_RS20075	COG0714	Associated with various cellular activities
EI427_RS20085	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EI427_RS20110	COG0456	acetyltransferase
EI427_RS20115	COG0686	Belongs to the AlaDH PNT family
EI427_RS20125	COG1331	Highly conserved protein containing a thioredoxin domain
EI427_RS20135	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EI427_RS20180	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EI427_RS20185	COG0443	Heat shock 70 kDa protein
EI427_RS20195	COG0686	Belongs to the AlaDH PNT family
EI427_RS20200	COG4942	peptidase
EI427_RS20240	COG2226	methyltransferase
EI427_RS20250	COG2885	chlorophyll binding
EI427_RS20250	COG3047	cAMP biosynthetic process
EI427_RS20260	COG2151	metal-sulfur cluster biosynthetic enzyme
EI427_RS20265	COG2166	iron-sulfur cluster assembly
EI427_RS20270	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EI427_RS20305	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EI427_RS20315	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EI427_RS20320	COG0134	indole-3-glycerol-phosphate synthase activity
EI427_RS20330	COG0135	phosphoribosylanthranilate isomerase activity
EI427_RS20335	COG0133	tryptophan synthase activity
EI427_RS20340	COG3613	nucleoside 2-deoxyribosyltransferase
EI427_RS20345	COG4251	negative regulation of phosphorylation
EI427_RS20410	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EI427_RS20425	COG1649	PFAM Uncharacterised BCR, COG1649
EI427_RS20455	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EI427_RS20460	COG2010	Cytochrome c
EI427_RS20525	COG1979	alcohol dehydrogenase
EI427_RS20530	COG1028	Short-chain dehydrogenase reductase Sdr
EI427_RS20535	COG2197	response regulator
EI427_RS20545	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EI427_RS20550	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EI427_RS20550	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EI427_RS20555	COG0436	Aminotransferase
EI427_RS20575	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EI427_RS20580	COG1192	Involved in chromosome partitioning
EI427_RS20590	COG0835	chemotaxis
EI427_RS20595	COG2201	protein-glutamate methylesterase activity
EI427_RS20605	COG0484	heat shock protein binding
EI427_RS20660	COG1132	(ABC) transporter
EI427_RS20705	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EI427_RS20710	COG1333	cytochrome c biogenesis protein
EI427_RS20710	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EI427_RS20740	COG2249	NAD(P)H dehydrogenase (quinone) activity
EI427_RS20765	COG4452	Inner membrane protein CreD
EI427_RS20795	COG3119	arylsulfatase activity
EI427_RS20805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EI427_RS20815	COG1538	Outer membrane efflux protein
EI427_RS20820	COG3275	phosphorelay sensor kinase activity
EI427_RS20845	COG1136	(ABC) transporter
EI427_RS20850	COG0577	efflux transmembrane transporter activity
EI427_RS20860	COG2204	response regulator
EI427_RS20885	COG5492	domain, Protein
EI427_RS20905	COG3250	beta-galactosidase activity
EI427_RS20920	COG3119	arylsulfatase activity
EI427_RS20935	COG0714	Associated with various cellular activities
EI427_RS20975	COG3275	phosphorelay sensor kinase activity
EI427_RS20980	COG3279	Response regulator of the LytR AlgR family
EI427_RS21120	COG2837	iron assimilation
EI427_RS21165	COG0517	IMP dehydrogenase activity
EI427_RS21180	COG1881	PFAM PEBP family protein
EI427_RS21230	COG1136	(ABC) transporter
EI427_RS21240	COG0577	efflux transmembrane transporter activity
EI427_RS21240	COG1136	(ABC) transporter
EI427_RS21260	COG1131	(ABC) transporter
EI427_RS21300	COG3119	arylsulfatase activity
EI427_RS21330	COG2205	protein histidine kinase activity
EI427_RS21330	COG3292	Two component regulator propeller
EI427_RS21330	COG0745	RESPONSE REGULATOR receiver
EI427_RS21340	COG4771	TonB-dependent receptor
EI427_RS21345	COG0702	epimerase
EI427_RS21370	COG3119	arylsulfatase activity
EI427_RS21385	COG0189	ligase activity
EI427_RS21390	COG4067	protein conserved in archaea
EI427_RS21390	COG0189	ligase activity
EI427_RS21420	COG4977	sequence-specific DNA binding
EI427_RS21455	COG4771	TonB-dependent receptor
EI427_RS21475	COG3119	arylsulfatase activity
EI427_RS21480	COG3250	beta-galactosidase activity
EI427_RS21490	COG3119	arylsulfatase activity
EI427_RS21495	COG3119	arylsulfatase activity
EI427_RS21505	COG4771	TonB-dependent receptor
EI427_RS21515	COG3292	Two component regulator propeller
EI427_RS21515	COG0745	RESPONSE REGULATOR receiver
EI427_RS21515	COG2205	protein histidine kinase activity
EI427_RS21520	COG3250	beta-galactosidase activity
EI427_RS21530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EI427_RS21665	COG3119	arylsulfatase activity
EI427_RS21685	COG3119	arylsulfatase activity
EI427_RS21690	COG3119	arylsulfatase activity
EI427_RS21695	COG3119	arylsulfatase activity
EI427_RS21705	COG1472	Belongs to the glycosyl hydrolase 3 family
EI427_RS21710	COG1629	transport
EI427_RS21720	COG3119	arylsulfatase activity
EI427_RS21730	COG0745	RESPONSE REGULATOR receiver
EI427_RS21730	COG3292	Two component regulator propeller
EI427_RS21730	COG2205	protein histidine kinase activity
EI427_RS21760	COG0561	phosphatase activity
EI427_RS21780	COG3119	arylsulfatase activity
EI427_RS21785	COG3119	arylsulfatase activity
EI427_RS21790	COG3119	arylsulfatase activity
EI427_RS21805	COG1472	Belongs to the glycosyl hydrolase 3 family
EI427_RS21840	COG3867	Arabinogalactan endo-beta-1,4-galactanase
EI427_RS21855	COG3867	Arabinogalactan endo-beta-1,4-galactanase
EI427_RS21865	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EI427_RS21870	COG4206	TonB-dependent receptor
EI427_RS21870	COG1629	transport
EI427_RS21900	COG3250	beta-galactosidase activity
EI427_RS21905	COG2205	protein histidine kinase activity
EI427_RS21905	COG3292	Two component regulator propeller
EI427_RS21905	COG0745	RESPONSE REGULATOR receiver
EI427_RS21925	COG0702	epimerase
EI427_RS21930	COG1629	transport
EI427_RS21950	COG0800	Aldolase
EI427_RS21955	COG3734	2-keto-3-deoxy-galactonokinase
EI427_RS21960	COG1012	belongs to the aldehyde dehydrogenase family
EI427_RS21965	COG4948	Mandelate Racemase Muconate Lactonizing
EI427_RS22000	COG2814	Major facilitator Superfamily
EI427_RS22070	COG3012	SEC-C Motif Domain Protein
EI427_RS22100	COG3291	Pkd domain containing protein
EI427_RS22145	COG0598	Magnesium transport protein CorA
EI427_RS22155	COG0101	tRNA pseudouridine synthase activity
EI427_RS22160	COG1683	Conserved Protein
EI427_RS22265	COG3781	membrane
EI427_RS22275	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
EI427_RS22280	COG1070	Carbohydrate kinase
EI427_RS22290	COG1943	Transposase
EI427_RS22295	COG1012	belongs to the aldehyde dehydrogenase family
EI427_RS22300	COG0235	Class ii aldolase
EI427_RS22305	COG0247	lactate metabolic process
EI427_RS22310	COG1139	Iron-sulfur cluster binding protein
EI427_RS22330	COG0738	Major facilitator superfamily
EI427_RS22340	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EI427_RS22345	COG2197	response regulator
EI427_RS22365	COG1472	Belongs to the glycosyl hydrolase 3 family
EI427_RS22370	COG4206	TonB-dependent receptor
EI427_RS22370	COG1629	transport
EI427_RS22375	COG0702	epimerase
EI427_RS22405	COG3119	arylsulfatase activity
EI427_RS22410	COG3250	beta-galactosidase activity
EI427_RS22425	COG3119	arylsulfatase activity
EI427_RS22450	COG2304	oxidoreductase activity
EI427_RS22490	COG2095	MarC family integral membrane protein
EI427_RS22540	COG1629	transport
EI427_RS22545	COG0702	epimerase
EI427_RS22575	COG1063	alcohol dehydrogenase
EI427_RS22580	COG0156	8-amino-7-oxononanoate synthase activity
EI427_RS22610	COG0673	inositol 2-dehydrogenase activity
EI427_RS22630	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EI427_RS22670	COG3292	Two component regulator propeller
EI427_RS22670	COG0745	RESPONSE REGULATOR receiver
EI427_RS22670	COG2205	protein histidine kinase activity
EI427_RS22680	COG4771	TonB-dependent receptor
EI427_RS22685	COG0702	epimerase
EI427_RS22695	COG1082	Xylose isomerase domain protein TIM barrel
EI427_RS22725	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EI427_RS22770	COG1538	Outer membrane efflux protein
EI427_RS22780	COG3119	arylsulfatase activity
EI427_RS22830	COG4771	TonB-dependent receptor
EI427_RS22835	COG0702	epimerase
EI427_RS22865	COG2925	Exonuclease
EI427_RS22925	COG1950	PFAM Membrane protein of
EI427_RS22960	COG3681	Belongs to the UPF0597 family
EI427_RS22995	COG1012	belongs to the aldehyde dehydrogenase family
EI427_RS23005	COG0596	Alpha beta hydrolase
EI427_RS23020	COG1785	Belongs to the alkaline phosphatase family
EI427_RS23060	COG4657	Part of a membrane complex involved in electron transport
EI427_RS23065	COG4660	Part of a membrane complex involved in electron transport
EI427_RS23070	COG4659	FMN binding
EI427_RS23075	COG4658	electron transport chain
EI427_RS23080	COG4656	Part of a membrane complex involved in electron transport
EI427_RS23085	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EI427_RS23085	COG1013	pyruvate-flavodoxin oxidoreductase activity
EI427_RS23085	COG0674	pyruvate-flavodoxin oxidoreductase activity
EI427_RS23085	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EI427_RS23130	COG3119	arylsulfatase activity
EI427_RS23135	COG3119	arylsulfatase activity
EI427_RS23140	COG3250	beta-galactosidase activity
EI427_RS23145	COG3119	arylsulfatase activity
EI427_RS23170	COG3292	Two component regulator propeller
EI427_RS23170	COG0745	RESPONSE REGULATOR receiver
EI427_RS23170	COG2205	protein histidine kinase activity
EI427_RS23180	COG3459	Glycosyltransferase 36 associated
EI427_RS23185	COG2211	Major facilitator Superfamily
EI427_RS23190	COG1472	Belongs to the glycosyl hydrolase 3 family
EI427_RS23200	COG0668	transmembrane transport
EI427_RS23210	COG4771	TonB-dependent receptor
EI427_RS23220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EI427_RS23275	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EI427_RS23280	COG0659	secondary active sulfate transmembrane transporter activity
EI427_RS23315	COG3119	arylsulfatase activity
EI427_RS23345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EI427_RS23365	COG0446	pyridine nucleotide-disulphide oxidoreductase
EI427_RS23390	COG3292	Two component regulator propeller
EI427_RS23390	COG2205	protein histidine kinase activity
EI427_RS23390	COG0745	RESPONSE REGULATOR receiver
EI427_RS23395	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EI427_RS23405	COG1595	DNA-templated transcription, initiation
EI427_RS23520	COG0657	acetylesterase activity
EI427_RS23520	COG2755	lipolytic protein G-D-S-L family
EI427_RS23540	COG2814	Major facilitator Superfamily
EI427_RS23550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EI427_RS23560	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EI427_RS23565	COG2354	Protein conserved in bacteria
EI427_RS23575	COG0513	Belongs to the DEAD box helicase family
EI427_RS23625	COG1028	Short-chain dehydrogenase reductase Sdr
EI427_RS23655	COG1294	oxidase, subunit
EI427_RS23660	COG1271	oxidase subunit
EI427_RS23670	COG0308	aminopeptidase N
EI427_RS23700	COG0531	amino acid
EI427_RS23705	COG0038	chloride channel
EI427_RS23720	COG0688	phosphatidylethanolamine metabolic process
EI427_RS23820	COG3292	Two component regulator propeller
EI427_RS23820	COG2205	protein histidine kinase activity
EI427_RS23820	COG0745	RESPONSE REGULATOR receiver
EI427_RS23835	COG2207	Transcriptional regulator
EI427_RS23835	COG1917	Cupin 2, conserved barrel domain protein
EI427_RS23845	COG3250	beta-galactosidase activity
EI427_RS23855	COG1629	transport
EI427_RS23895	COG2197	response regulator
EI427_RS23965	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EI427_RS23975	COG3275	phosphorelay sensor kinase activity
EI427_RS23980	COG3279	Response regulator of the LytR AlgR family
EI427_RS23985	COG1227	inorganic diphosphatase activity
EI427_RS23990	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
EI427_RS24020	COG0438	transferase activity, transferring glycosyl groups
EI427_RS24065	COG0110	maltose O-acetyltransferase activity
EI427_RS24075	COG1215	transferase activity, transferring glycosyl groups
EI427_RS24110	COG2252	PERMEase
EI427_RS24120	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EI427_RS24135	COG0534	Mate efflux family protein
EI427_RS24145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EI427_RS24150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EI427_RS24160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EI427_RS24175	COG1028	Short-chain dehydrogenase reductase Sdr
EI427_RS24195	COG0445	tRNA wobble uridine modification
EI427_RS24200	COG3119	arylsulfatase activity
EI427_RS24205	COG3119	arylsulfatase activity
EI427_RS24210	COG3119	arylsulfatase activity
EI427_RS24215	COG3119	arylsulfatase activity
EI427_RS24225	COG2169	Transcriptional regulator
EI427_RS24230	COG3119	arylsulfatase activity
EI427_RS24240	COG2226	methyltransferase
EI427_RS24250	COG1770	oligopeptidase
EI427_RS24265	COG1770	oligopeptidase
EI427_RS24355	COG3119	arylsulfatase activity
EI427_RS24375	COG1643	Atp-dependent helicase
EI427_RS24400	COG1017	nitric oxide dioxygenase activity
EI427_RS24400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EI427_RS24430	COG4628	conserved protein (DUF2132)
EI427_RS24445	COG3537	Alpha-1,2-mannosidase
EI427_RS24460	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EI427_RS24465	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EI427_RS24525	COG3344	reverse transcriptase
EI427_RS24540	COG0517	IMP dehydrogenase activity
EI427_RS24570	COG4974	Belongs to the 'phage' integrase family
EI427_RS24575	COG2205	protein histidine kinase activity
EI427_RS24600	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EI427_RS24630	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EI427_RS24640	COG1136	(ABC) transporter
EI427_RS24690	COG4977	sequence-specific DNA binding
EI427_RS24695	COG0076	glutamate decarboxylase activity
EI427_RS24700	COG3486	L-lysine 6-monooxygenase (NADPH) activity
EI427_RS24725	COG0668	transmembrane transport
EI427_RS24750	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EI427_RS24755	COG2897	thiosulfate sulfurtransferase activity
EI427_RS24770	COG2918	glutathione biosynthetic process
EI427_RS24770	COG0189	ligase activity
EI427_RS24775	COG0534	Mate efflux family protein
EI427_RS24800	COG0702	epimerase
EI427_RS24805	COG4206	TonB-dependent receptor
EI427_RS24805	COG1629	transport
EI427_RS24825	COG3537	Alpha-1,2-mannosidase
EI427_RS24865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EI427_RS24875	COG1028	Short-chain dehydrogenase reductase Sdr
EI427_RS24880	COG0583	DNA-binding transcription factor activity
EI427_RS24900	COG0039	L-malate dehydrogenase activity
EI427_RS24915	COG1492	cobalamin metabolic process
EI427_RS24940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EI427_RS24980	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
EI427_RS25000	COG1797	cobyrinic acid a,c-diamide synthase activity
EI427_RS25005	COG2096	Adenosyltransferase
EI427_RS25095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EI427_RS25105	COG0202	RNA polymerase activity
EI427_RS25110	COG1022	Amp-dependent synthetase and ligase
EI427_RS25200	COG0483	inositol monophosphate 1-phosphatase activity
EI427_RS25225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EI427_RS25230	COG1522	sequence-specific DNA binding
EI427_RS25330	COG1609	Transcriptional regulator
EI427_RS25335	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EI427_RS25345	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EI427_RS25395	COG4948	Mandelate Racemase Muconate Lactonizing
EI427_RS25400	COG1012	belongs to the aldehyde dehydrogenase family
EI427_RS25405	COG1028	Short-chain dehydrogenase reductase Sdr
EI427_RS25410	COG1063	alcohol dehydrogenase
EI427_RS25415	COG3250	beta-galactosidase activity
EI427_RS25425	COG0702	epimerase
EI427_RS25430	COG4771	TonB-dependent receptor
EI427_RS25465	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EI427_RS25500	COG4771	TonB-dependent receptor
EI427_RS25695	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EI427_RS25725	COG4935	Belongs to the peptidase S8 family
EI427_RS25725	COG1404	Belongs to the peptidase S8 family
EI427_RS25790	COG2312	Erythromycin esterase