locus-tag	class	description
MY04_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MY04_RS00070	COG1217	gtp-binding protein TYPA
MY04_RS00095	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MY04_RS00100	COG0151	Belongs to the GarS family
MY04_RS00130	COG0688	phosphatidylethanolamine metabolic process
MY04_RS00135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MY04_RS00135	COG0321	lipoyl(octanoyl) transferase activity
MY04_RS00160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MY04_RS00165	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MY04_RS00180	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MY04_RS00190	COG2217	Heavy metal translocating P-type atpase
MY04_RS00225	COG1858	cytochrome C peroxidase
MY04_RS00230	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MY04_RS00240	COG4221	oxidoreductase activity
MY04_RS00250	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MY04_RS00260	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MY04_RS00285	COG3250	beta-galactosidase activity
MY04_RS00300	COG5434	Belongs to the glycosyl hydrolase 28 family
MY04_RS00305	COG4771	TonB-dependent receptor
MY04_RS00320	COG0745	RESPONSE REGULATOR receiver
MY04_RS00320	COG3292	Two component regulator propeller
MY04_RS00320	COG2205	protein histidine kinase activity
MY04_RS00330	COG0191	fructose-bisphosphate aldolase activity
MY04_RS00335	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MY04_RS00340	COG0772	Belongs to the SEDS family
MY04_RS00345	COG1752	Esterase of the alpha-beta hydrolase superfamily
MY04_RS00350	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MY04_RS00365	COG0745	RESPONSE REGULATOR receiver
MY04_RS00415	COG4771	TonB-dependent receptor
MY04_RS00420	COG0612	Peptidase, M16
MY04_RS00460	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MY04_RS00460	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MY04_RS00465	COG2329	Antibiotic biosynthesis monooxygenase
MY04_RS00480	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MY04_RS00490	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MY04_RS00505	COG4717	serine-type aminopeptidase activity
MY04_RS00510	COG0681	Belongs to the peptidase S26 family
MY04_RS00515	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MY04_RS00525	COG1475	DNA binding
MY04_RS00530	COG1192	Involved in chromosome partitioning
MY04_RS00535	COG0726	polysaccharide deacetylase
MY04_RS00545	COG0129	dihydroxy-acid dehydratase activity
MY04_RS00550	COG0028	Belongs to the TPP enzyme family
MY04_RS00555	COG0440	acetolactate synthase activity
MY04_RS00560	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MY04_RS00600	COG0564	pseudouridine synthase activity
MY04_RS00615	COG0367	asparagine synthase
MY04_RS00640	COG0860	N-Acetylmuramoyl-L-alanine amidase
MY04_RS00645	COG0805	protein transport
MY04_RS00650	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MY04_RS00660	COG1091	dTDP-4-dehydrorhamnose reductase activity
MY04_RS00690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MY04_RS00700	COG2050	protein possibly involved in aromatic compounds catabolism
MY04_RS00710	COG5000	phosphorelay sensor kinase activity
MY04_RS00735	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MY04_RS00790	COG1363	Peptidase, m42
MY04_RS00795	COG1335	isochorismatase
MY04_RS00800	COG1528	Iron-storage protein
MY04_RS00805	COG2086	electron transfer activity
MY04_RS00810	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MY04_RS00820	COG1196	nuclear chromosome segregation
MY04_RS00835	COG0439	Biotin carboxylase
MY04_RS00875	COG0175	sulfate reduction
MY04_RS00905	COG1703	isobutyryl-CoA mutase activity
MY04_RS00905	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MY04_RS00905	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MY04_RS00910	COG0745	RESPONSE REGULATOR receiver
MY04_RS00910	COG2972	Histidine kinase
MY04_RS00940	COG4771	TonB-dependent receptor
MY04_RS00945	COG0275	rRNA processing
MY04_RS00955	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MY04_RS00965	COG0281	malic enzyme
MY04_RS00975	COG1136	(ABC) transporter
MY04_RS00975	COG0577	efflux transmembrane transporter activity
MY04_RS00985	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
MY04_RS00990	COG1607	acyl-coa hydrolase
MY04_RS01015	COG3069	C4-dicarboxylate transmembrane transporter activity
MY04_RS01040	COG0105	UTP biosynthetic process
MY04_RS01045	COG1132	(ABC) transporter
MY04_RS01050	COG2719	SpoVR family
MY04_RS01055	COG2718	Belongs to the UPF0229 family
MY04_RS01060	COG2766	serine protein kinase
MY04_RS01070	COG2197	response regulator
MY04_RS01105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MY04_RS01115	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MY04_RS01125	COG4249	Peptidase C14 caspase catalytic subunit p20
MY04_RS01125	COG2319	Wd-40 repeat
MY04_RS01140	COG1705	Flagellar rod assembly protein muramidase FlgJ
MY04_RS01140	COG1388	LysM domain
MY04_RS01215	COG3604	Transcriptional regulator
MY04_RS01220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MY04_RS01225	COG0544	peptidyl-prolyl cis-trans isomerase activity
MY04_RS01230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MY04_RS01245	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
MY04_RS01250	COG0259	pyridoxamine-phosphate oxidase activity
MY04_RS01255	COG0004	ammonium transporteR
MY04_RS01265	COG0739	heme binding
MY04_RS01270	COG0492	ferredoxin-NADP+ reductase activity
MY04_RS01285	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MY04_RS01290	COG1610	YqeY-like protein
MY04_RS01300	COG0512	Glutamine amidotransferase of anthranilate synthase
MY04_RS01315	COG1012	belongs to the aldehyde dehydrogenase family
MY04_RS01320	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MY04_RS01330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MY04_RS01335	COG0714	Associated with various cellular activities
MY04_RS01355	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MY04_RS01365	COG1053	succinate dehydrogenase
MY04_RS01370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MY04_RS01395	COG4206	TonB-dependent receptor
MY04_RS01415	COG1136	(ABC) transporter
MY04_RS01415	COG0577	efflux transmembrane transporter activity
MY04_RS01425	COG0017	Asparaginyl-tRNA synthetase
MY04_RS01450	COG0456	acetyltransferase
MY04_RS01455	COG0429	hydrolase of the alpha beta-hydrolase fold
MY04_RS01465	COG0366	Alpha amylase catalytic
MY04_RS01475	COG0483	inositol monophosphate 1-phosphatase activity
MY04_RS01485	COG2249	NAD(P)H dehydrogenase (quinone) activity
MY04_RS01490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MY04_RS01505	COG2949	membrane
MY04_RS01550	COG1482	cell wall glycoprotein biosynthetic process
MY04_RS01565	COG2207	Transcriptional regulator
MY04_RS01595	COG0335	large ribosomal subunit rRNA binding
MY04_RS01650	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MY04_RS01670	COG1131	(ABC) transporter
MY04_RS01675	COG0656	L-ascorbic acid biosynthetic process
MY04_RS01690	COG1674	ftsk spoiiie
MY04_RS01715	COG0420	3'-5' exonuclease activity
MY04_RS01720	COG0419	ATPase involved in DNA repair
MY04_RS01725	COG1272	protein, Hemolysin III
MY04_RS01735	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MY04_RS01740	COG2177	Part of the ABC transporter FtsEX involved in
MY04_RS01755	COG0415	Belongs to the DNA photolyase family
MY04_RS01765	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MY04_RS01770	COG1561	YicC-like family, N-terminal region
MY04_RS01785	COG1028	Short-chain dehydrogenase reductase Sdr
MY04_RS01835	COG0343	queuine tRNA-ribosyltransferase activity
MY04_RS01855	COG4770	biotin carboxylase activity
MY04_RS01895	COG1131	(ABC) transporter
MY04_RS01905	COG1725	Transcriptional regulator
MY04_RS01915	COG0793	Belongs to the peptidase S41A family
MY04_RS01935	COG3119	arylsulfatase activity
MY04_RS01945	COG0484	heat shock protein binding
MY04_RS01950	COG1242	4 iron, 4 sulfur cluster binding
MY04_RS01975	COG0824	Thioesterase
MY04_RS01980	COG1073	alpha beta
MY04_RS02015	COG0006	proline dipeptidase activity
MY04_RS02020	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MY04_RS02050	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MY04_RS02070	COG1546	Belongs to the CinA family
MY04_RS02070	COG1058	Belongs to the CinA family
MY04_RS02090	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MY04_RS02115	COG3842	ATPase activity
MY04_RS02125	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MY04_RS02155	COG2040	homocysteine
MY04_RS02160	COG1022	Amp-dependent synthetase and ligase
MY04_RS02195	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MY04_RS02200	COG1012	belongs to the aldehyde dehydrogenase family
MY04_RS02215	COG0778	Nitroreductase
MY04_RS02240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MY04_RS02245	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
MY04_RS02245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MY04_RS02250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MY04_RS02255	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MY04_RS02265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MY04_RS02315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MY04_RS02320	COG0484	heat shock protein binding
MY04_RS02335	COG4172	Belongs to the ABC transporter superfamily
MY04_RS02380	COG1216	Glycosyl transferase, family 2
MY04_RS02385	COG0018	arginyl-trna synthetase
MY04_RS02420	COG0113	porphobilinogen synthase activity
MY04_RS02435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MY04_RS02440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MY04_RS02445	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MY04_RS02450	COG1216	Glycosyl transferase, family 2
MY04_RS02455	COG0110	maltose O-acetyltransferase activity
MY04_RS02510	COG0438	transferase activity, transferring glycosyl groups
MY04_RS02515	COG2327	Polysaccharide pyruvyl transferase
MY04_RS02530	COG0543	2 iron, 2 sulfur cluster binding
MY04_RS02530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MY04_RS02560	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MY04_RS02590	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MY04_RS02605	COG0459	protein refolding
MY04_RS02610	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MY04_RS02620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MY04_RS02620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MY04_RS02640	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MY04_RS02665	COG3781	membrane
MY04_RS02670	COG1218	3'(2'),5'-bisphosphate nucleotidase
MY04_RS02680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MY04_RS02685	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MY04_RS02690	COG4106	trans-aconitate 2-methyltransferase activity
MY04_RS02705	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MY04_RS02745	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MY04_RS02750	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MY04_RS02760	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MY04_RS02775	COG1716	ATPase activity
MY04_RS02775	COG0842	Transport permease protein
MY04_RS02775	COG1131	(ABC) transporter
MY04_RS02800	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MY04_RS02805	COG1349	DNA-binding transcription factor activity
MY04_RS02810	COG4771	TonB-dependent receptor
MY04_RS02820	COG4771	TonB-dependent receptor
MY04_RS02835	COG3142	Participates in the control of copper homeostasis
MY04_RS02870	COG1082	Xylose isomerase domain protein TIM barrel
MY04_RS02895	COG2837	iron assimilation
MY04_RS02900	COG0110	maltose O-acetyltransferase activity
MY04_RS02910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MY04_RS02925	COG0101	tRNA pseudouridine synthase activity
MY04_RS02935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MY04_RS02955	COG0488	(ABC) transporter
MY04_RS02965	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MY04_RS02975	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MY04_RS02985	COG0357	Ribosomal RNA small subunit methyltransferase G
MY04_RS02995	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MY04_RS03030	COG0494	nUDIX hydrolase
MY04_RS03035	COG0534	Mate efflux family protein
MY04_RS03060	COG3275	phosphorelay sensor kinase activity
MY04_RS03065	COG3279	Response regulator of the LytR AlgR family
MY04_RS03070	COG0617	tRNA 3'-terminal CCA addition
MY04_RS03070	COG0517	IMP dehydrogenase activity
MY04_RS03070	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MY04_RS03075	COG2353	YceI-like domain
MY04_RS03090	COG1136	(ABC) transporter
MY04_RS03100	COG1609	Transcriptional regulator
MY04_RS03105	COG4206	TonB-dependent receptor
MY04_RS03105	COG1629	transport
MY04_RS03110	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MY04_RS03125	COG0366	Alpha amylase catalytic
MY04_RS03130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MY04_RS03135	COG2885	chlorophyll binding
MY04_RS03155	COG0737	Belongs to the 5'-nucleotidase family
MY04_RS03160	COG2072	flavoprotein involved in K transport
MY04_RS03195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MY04_RS03215	COG0659	secondary active sulfate transmembrane transporter activity
MY04_RS03220	COG1132	(ABC) transporter
MY04_RS03260	COG1595	DNA-templated transcription, initiation
MY04_RS03275	COG4206	TonB-dependent receptor
MY04_RS03275	COG1629	transport
MY04_RS03340	COG1943	Transposase
MY04_RS03380	COG1584	GPR1 FUN34 yaaH family protein
MY04_RS03395	COG0514	ATP-dependent DNA helicase (RecQ)
MY04_RS03405	COG4804	nuclease activity
MY04_RS03425	COG0732	type I restriction modification DNA specificity domain
MY04_RS03430	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MY04_RS03450	COG1629	transport
MY04_RS03470	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MY04_RS03505	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MY04_RS03515	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MY04_RS03540	COG2176	DNA-directed DNA polymerase activity
MY04_RS03555	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MY04_RS03565	COG0702	epimerase
MY04_RS03570	COG4771	TonB-dependent receptor
MY04_RS03600	COG1505	serine-type exopeptidase activity
MY04_RS03620	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MY04_RS03655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MY04_RS03670	COG1733	regulation of RNA biosynthetic process
MY04_RS03755	COG0385	Bile acid
MY04_RS03760	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MY04_RS03765	COG1250	3-hydroxyacyl-CoA dehydrogenase
MY04_RS03795	COG0405	Gamma-glutamyltransferase
MY04_RS03805	COG3781	membrane
MY04_RS03815	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MY04_RS03820	COG1595	DNA-templated transcription, initiation
MY04_RS03830	COG1129	ABC transporter
MY04_RS03830	COG0842	Transport permease protein
MY04_RS03835	COG0842	Transport permease protein
MY04_RS03840	COG1131	(ABC) transporter
MY04_RS03845	COG1131	(ABC) transporter
MY04_RS03850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MY04_RS03860	COG1309	transcriptional regulator
MY04_RS03870	COG0667	Aldo Keto reductase
MY04_RS03875	COG1187	pseudouridine synthase activity
MY04_RS03880	COG1960	acyl-CoA dehydrogenase activity
MY04_RS03905	COG0628	permease
MY04_RS03935	COG3279	Response regulator of the LytR AlgR family
MY04_RS03965	COG0540	Belongs to the ATCase OTCase family
MY04_RS03970	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MY04_RS03975	COG1051	belongs to the nudix hydrolase family
MY04_RS04000	COG0495	leucyl-tRNA aminoacylation
MY04_RS04020	COG0019	diaminopimelate decarboxylase activity
MY04_RS04115	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MY04_RS04130	COG5002	protein histidine kinase activity
MY04_RS04135	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MY04_RS04145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MY04_RS04160	COG0649	NAD binding
MY04_RS04185	COG0300	oxidoreductase activity
MY04_RS04200	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MY04_RS04205	COG0514	ATP-dependent DNA helicase (RecQ)
MY04_RS04210	COG0167	dihydroorotate dehydrogenase activity
MY04_RS04225	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MY04_RS04360	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MY04_RS04375	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MY04_RS04405	COG2353	YceI-like domain
MY04_RS04415	COG1640	4-alpha-glucanotransferase
MY04_RS04450	COG0386	Belongs to the glutathione peroxidase family
MY04_RS04460	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MY04_RS04500	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MY04_RS04505	COG0617	tRNA 3'-terminal CCA addition
MY04_RS04505	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MY04_RS04505	COG0517	IMP dehydrogenase activity
MY04_RS04530	COG0438	transferase activity, transferring glycosyl groups
MY04_RS04540	COG2081	HI0933 family
MY04_RS04565	COG1388	LysM domain
MY04_RS04565	COG3942	CHAP domain
MY04_RS04570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MY04_RS04580	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MY04_RS04580	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MY04_RS04585	COG0038	chloride channel
MY04_RS04600	COG0778	Nitroreductase
MY04_RS04620	COG4372	Transposase
MY04_RS04625	COG0217	transcriptional regulatory protein
MY04_RS04635	COG1940	carbohydrate kinase activity
MY04_RS04645	COG1393	Belongs to the ArsC family
MY04_RS04650	COG1703	isobutyryl-CoA mutase activity
MY04_RS04655	COG0346	lactoylglutathione lyase activity
MY04_RS04660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MY04_RS04675	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
MY04_RS04680	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MY04_RS04685	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MY04_RS04685	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MY04_RS04695	COG1028	Short-chain dehydrogenase reductase Sdr
MY04_RS04705	COG1629	transport
MY04_RS04705	COG4206	TonB-dependent receptor
MY04_RS04715	COG1629	transport
MY04_RS04715	COG4206	TonB-dependent receptor
MY04_RS04725	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MY04_RS04735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MY04_RS04755	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MY04_RS04760	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
MY04_RS04770	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MY04_RS04800	COG0424	maF-like protein
MY04_RS04805	COG4399	Belongs to the UPF0754 family
MY04_RS04815	COG0564	pseudouridine synthase activity
MY04_RS04850	COG0523	cobalamin synthesis protein
MY04_RS04855	COG0360	Binds together with S18 to 16S ribosomal RNA
MY04_RS04860	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MY04_RS04865	COG0359	binds to the 23S rRNA
MY04_RS04870	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MY04_RS04875	COG1446	asparaginase
MY04_RS04880	COG3537	Alpha-1,2-mannosidase
MY04_RS04885	COG3525	Glycosyl hydrolase, family 20, catalytic domain
MY04_RS04890	COG3537	Alpha-1,2-mannosidase
MY04_RS04915	COG0545	Peptidyl-prolyl cis-trans isomerase
MY04_RS04930	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MY04_RS04935	COG1575	Belongs to the MenA family. Type 1 subfamily
MY04_RS04945	COG1570	exodeoxyribonuclease VII activity
MY04_RS04950	COG1722	exodeoxyribonuclease VII activity
MY04_RS04965	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
MY04_RS04975	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MY04_RS05010	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MY04_RS05010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MY04_RS05050	COG1929	Belongs to the glycerate kinase type-1 family
MY04_RS05055	COG0758	DNA mediated transformation
MY04_RS05055	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MY04_RS05060	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MY04_RS05070	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MY04_RS05080	COG0735	belongs to the Fur family
MY04_RS05090	COG0813	purine-nucleoside phosphorylase activity
MY04_RS05095	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MY04_RS05100	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MY04_RS05110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MY04_RS05135	COG4864	UPF0365 protein
MY04_RS05140	COG0826	peptidase U32
MY04_RS05145	COG1301	dicarboxylic acid transport
MY04_RS05150	COG1506	peptidase
MY04_RS05150	COG0823	Involved in the tonB-independent uptake of proteins
MY04_RS05170	COG2195	Cleaves the N-terminal amino acid of tripeptides
MY04_RS05175	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MY04_RS05185	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MY04_RS05190	COG0602	queuosine metabolic process
MY04_RS05195	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MY04_RS05200	COG1803	Methylglyoxal synthase
MY04_RS05215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MY04_RS05225	COG1132	(ABC) transporter
MY04_RS05295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MY04_RS05300	COG1183	phosphatidylcholine synthase activity
MY04_RS05315	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MY04_RS05320	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MY04_RS05330	COG0427	acetyl-CoA hydrolase
MY04_RS05335	COG0124	histidyl-tRNA synthetase
MY04_RS05345	COG1363	Peptidase, m42
MY04_RS05370	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MY04_RS05380	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MY04_RS05385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MY04_RS05390	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MY04_RS05400	COG0439	Biotin carboxylase
MY04_RS05415	COG1760	l-serine dehydratase
MY04_RS05420	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MY04_RS05425	COG0589	response to stress
MY04_RS05445	COG0469	pyruvate kinase activity
MY04_RS05450	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MY04_RS05455	COG0513	Belongs to the DEAD box helicase family
MY04_RS05460	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MY04_RS05470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MY04_RS05475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MY04_RS05480	COG0179	Fumarylacetoacetate (FAA) hydrolase
MY04_RS05495	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MY04_RS05510	COG0791	NLP P60 protein
MY04_RS05520	COG0569	domain protein
MY04_RS05525	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MY04_RS05530	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MY04_RS05535	COG0305	Participates in initiation and elongation during chromosome replication
MY04_RS05545	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MY04_RS05550	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MY04_RS05620	COG0156	8-amino-7-oxononanoate synthase activity
MY04_RS05635	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MY04_RS05650	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MY04_RS05670	COG0746	molybdenum cofactor guanylyltransferase activity
MY04_RS05685	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MY04_RS05695	COG1137	ATPase activity
MY04_RS05705	COG0788	formyltetrahydrofolate deformylase activity
MY04_RS05710	COG5016	pyruvate
MY04_RS05710	COG0511	ligase activity, forming carbon-carbon bonds
MY04_RS05715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MY04_RS05735	COG1663	tetraacyldisaccharide 4'-kinase activity
MY04_RS05740	COG0045	succinate-CoA ligase (ADP-forming) activity
MY04_RS05745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MY04_RS05745	COG1754	DNA topoisomerase type I activity
MY04_RS05770	COG2884	Cell division ATP-binding protein ftsE
MY04_RS05780	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MY04_RS05785	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MY04_RS05790	COG0039	L-malate dehydrogenase activity
MY04_RS05795	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MY04_RS05800	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MY04_RS05815	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MY04_RS05815	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MY04_RS05825	COG3186	Phenylalanine-4-hydroxylase
MY04_RS05835	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MY04_RS05850	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MY04_RS05855	COG0756	dUTP diphosphatase activity
MY04_RS05865	COG1024	Enoyl-CoA hydratase
MY04_RS05875	COG1360	Flagellar Motor Protein
MY04_RS05890	COG0187	DNA topoisomerase II activity
MY04_RS05895	COG1560	Kdo2-lipid A biosynthetic process
MY04_RS05910	COG1028	Short-chain dehydrogenase reductase Sdr
MY04_RS05930	COG1231	oxidoreductase activity
MY04_RS05995	COG4372	Transposase
MY04_RS06090	COG4399	Belongs to the UPF0754 family
MY04_RS06120	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
MY04_RS06125	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MY04_RS06125	COG0047	phosphoribosylformylglycinamidine synthase activity
MY04_RS06135	COG0616	signal peptide processing
MY04_RS06170	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
MY04_RS06190	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MY04_RS06200	COG0217	transcriptional regulatory protein
MY04_RS06205	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MY04_RS06210	COG2239	Acts as a magnesium transporter
MY04_RS06275	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MY04_RS06280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MY04_RS06285	COG0180	Tryptophanyl-tRNA synthetase
MY04_RS06300	COG1120	ATPase activity
MY04_RS06305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MY04_RS06310	COG0546	phosphoglycolate phosphatase activity
MY04_RS06315	COG2366	antibiotic biosynthetic process
MY04_RS06330	COG4372	Transposase
MY04_RS06355	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MY04_RS06360	COG5000	phosphorelay sensor kinase activity
MY04_RS06370	COG2322	membrane
MY04_RS06385	COG1845	cytochrome c oxidase, subunit III
MY04_RS06390	COG1845	cytochrome c oxidase, subunit III
MY04_RS06395	COG0109	protoheme IX farnesyltransferase activity
MY04_RS06410	COG0037	tRNA processing
MY04_RS06425	COG1522	sequence-specific DNA binding
MY04_RS06435	COG0527	aspartate kinase activity
MY04_RS06455	COG0251	oxidation-reduction process
MY04_RS06460	COG0280	phosphate acetyltransferase
MY04_RS06460	COG0857	belongs to the CobB CobQ family
MY04_RS06465	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MY04_RS06475	COG0415	Belongs to the DNA photolyase family
MY04_RS06480	COG3046	protein related to deoxyribodipyrimidine photolyase
MY04_RS06490	COG0513	Belongs to the DEAD box helicase family
MY04_RS06505	COG1380	Effector of murein hydrolase LrgA
MY04_RS06510	COG1346	cytolysis
MY04_RS06540	COG0527	aspartate kinase activity
MY04_RS06545	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MY04_RS06550	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MY04_RS06560	COG1629	transport
MY04_RS06570	COG1629	transport
MY04_RS06585	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MY04_RS06620	COG0148	phosphopyruvate hydratase activity
MY04_RS06625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MY04_RS06640	COG0848	biopolymer transport protein
MY04_RS06645	COG0811	peptide transport
MY04_RS06665	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MY04_RS06670	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MY04_RS06675	COG2095	MarC family integral membrane protein
MY04_RS06690	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MY04_RS06720	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MY04_RS06730	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MY04_RS06735	COG2224	Isocitrate lyase
MY04_RS06745	COG0488	(ABC) transporter
MY04_RS06750	COG2885	chlorophyll binding
MY04_RS06755	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MY04_RS06760	COG1696	Membrane protein involved in D-alanine export
MY04_RS06815	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MY04_RS06820	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MY04_RS06825	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MY04_RS06830	COG0488	(ABC) transporter
MY04_RS06865	COG4145	pantothenate transmembrane transporter activity
MY04_RS06875	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MY04_RS06880	COG1917	Cupin 2, conserved barrel domain protein
MY04_RS06880	COG2169	Transcriptional regulator
MY04_RS06910	COG3876	Protein conserved in bacteria
MY04_RS06915	COG1472	Belongs to the glycosyl hydrolase 3 family
MY04_RS06935	COG0719	Fe-S assembly protein
MY04_RS06940	COG0396	ATPase activity
MY04_RS06950	COG3781	membrane
MY04_RS06960	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MY04_RS06965	COG0242	peptide deformylase activity
MY04_RS06975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MY04_RS06990	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MY04_RS07000	COG0297	glycogen (starch) synthase activity
MY04_RS07005	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MY04_RS07020	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MY04_RS07030	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MY04_RS07035	COG5002	protein histidine kinase activity
MY04_RS07035	COG2198	Histidine kinase
MY04_RS07035	COG0784	Response regulator, receiver
MY04_RS07040	COG1007	ATP synthesis coupled electron transport
MY04_RS07045	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MY04_RS07050	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MY04_RS07055	COG0713	ATP synthesis coupled electron transport
MY04_RS07075	COG2124	cytochrome p450
MY04_RS07080	COG1228	amidohydrolase
MY04_RS07085	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MY04_RS07090	COG2986	histidine ammonia-lyase
MY04_RS07110	COG2197	response regulator
MY04_RS07115	COG0738	Major facilitator superfamily
MY04_RS07120	COG4399	Belongs to the UPF0754 family
MY04_RS07190	COG2181	nitrate reductase activity
MY04_RS07190	COG0247	lactate metabolic process
MY04_RS07195	COG2181	nitrate reductase activity
MY04_RS07195	COG0247	lactate metabolic process
MY04_RS07205	COG3340	Belongs to the peptidase S51 family
MY04_RS07210	COG0484	heat shock protein binding
MY04_RS07215	COG0148	phosphopyruvate hydratase activity
MY04_RS07220	COG3604	Transcriptional regulator
MY04_RS07255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MY04_RS07260	COG0508	dehydrogenase complex catalyzes the overall conversion of
MY04_RS07280	COG0792	nuclease activity
MY04_RS07290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MY04_RS07315	COG1136	(ABC) transporter
MY04_RS07320	COG1136	(ABC) transporter
MY04_RS07320	COG0577	efflux transmembrane transporter activity
MY04_RS07325	COG0577	efflux transmembrane transporter activity
MY04_RS07325	COG1136	(ABC) transporter
MY04_RS07335	COG2204	response regulator
MY04_RS07340	COG4191	Histidine kinase
MY04_RS07345	COG0673	inositol 2-dehydrogenase activity
MY04_RS07360	COG2211	Major facilitator Superfamily
MY04_RS07365	COG5434	Belongs to the glycosyl hydrolase 28 family
MY04_RS07370	COG0673	inositol 2-dehydrogenase activity
MY04_RS07375	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
MY04_RS07395	COG4771	TonB-dependent receptor
MY04_RS07410	COG1028	Short-chain dehydrogenase reductase Sdr
MY04_RS07420	COG1028	Short-chain dehydrogenase reductase Sdr
MY04_RS07430	COG0318	PFAM AMP-dependent synthetase and ligase
MY04_RS07450	COG0686	Belongs to the AlaDH PNT family
MY04_RS07455	COG1012	belongs to the aldehyde dehydrogenase family
MY04_RS07460	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MY04_RS07465	COG1012	belongs to the aldehyde dehydrogenase family
MY04_RS07485	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MY04_RS07490	COG0859	PFAM glycosyl transferase family 9
MY04_RS07500	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MY04_RS07520	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MY04_RS07520	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MY04_RS07555	COG1842	Phage shock protein A
MY04_RS07570	COG1960	acyl-CoA dehydrogenase activity
MY04_RS07575	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MY04_RS07580	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MY04_RS07590	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MY04_RS07610	COG1233	COG1233 Phytoene dehydrogenase and related
MY04_RS07615	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
MY04_RS07635	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MY04_RS07645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MY04_RS07690	COG0706	membrane insertase activity
MY04_RS07695	COG0504	CTP synthase activity
MY04_RS07715	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MY04_RS07745	COG2197	response regulator
MY04_RS07760	COG3781	membrane
MY04_RS07770	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MY04_RS07775	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MY04_RS07780	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MY04_RS07785	COG3185	4-Hydroxyphenylpyruvate dioxygenase
MY04_RS07795	COG0632	four-way junction helicase activity
MY04_RS07820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MY04_RS07825	COG0860	N-Acetylmuramoyl-L-alanine amidase
MY04_RS07830	COG0010	Belongs to the arginase family
MY04_RS07860	COG0183	Belongs to the thiolase family
MY04_RS07880	COG2116	formate transmembrane transporter activity
MY04_RS07895	COG0534	Mate efflux family protein
MY04_RS07900	COG5002	protein histidine kinase activity
MY04_RS07915	COG5002	protein histidine kinase activity
MY04_RS07980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MY04_RS07985	COG0745	RESPONSE REGULATOR receiver
MY04_RS07990	COG5002	protein histidine kinase activity
MY04_RS07995	COG0564	pseudouridine synthase activity
MY04_RS08035	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MY04_RS08040	COG1454	alcohol dehydrogenase
MY04_RS08050	COG0493	'glutamate synthase
MY04_RS08055	COG0070	glutamate synthase
MY04_RS08055	COG0069	glutamate synthase activity
MY04_RS08055	COG0067	glutamate synthase
MY04_RS08060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MY04_RS08065	COG0037	tRNA processing
MY04_RS08085	COG4249	Peptidase C14 caspase catalytic subunit p20
MY04_RS08085	COG2319	Wd-40 repeat
MY04_RS08095	COG0656	L-ascorbic acid biosynthetic process
MY04_RS08100	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MY04_RS08105	COG0516	GMP reductase activity
MY04_RS08105	COG0517	IMP dehydrogenase activity
MY04_RS08130	COG0579	oxidoreductase
MY04_RS08135	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MY04_RS08140	COG1115	amino acid carrier protein
MY04_RS08145	COG1193	negative regulation of DNA recombination
MY04_RS08160	COG2171	N-acyltransferase activity
MY04_RS08170	COG1649	PFAM Uncharacterised BCR, COG1649
MY04_RS08190	COG2210	Belongs to the sulfur carrier protein TusA family
MY04_RS08200	COG0604	alcohol dehydrogenase
MY04_RS08230	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MY04_RS08255	COG0525	valine-tRNA ligase activity
MY04_RS08265	COG3800	Transcriptional regulator
MY04_RS08265	COG1396	sequence-specific DNA binding
MY04_RS08270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MY04_RS08285	COG3011	Protein conserved in bacteria
MY04_RS08325	COG0720	synthase
MY04_RS08340	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MY04_RS08345	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MY04_RS08355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MY04_RS08360	COG0107	imidazoleglycerol-phosphate synthase activity
MY04_RS08365	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MY04_RS08395	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MY04_RS08400	COG1629	transport
MY04_RS08400	COG4206	TonB-dependent receptor
MY04_RS08405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MY04_RS08420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MY04_RS08430	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MY04_RS08460	COG1122	ATPase activity
MY04_RS08475	COG1605	Chorismate mutase
MY04_RS08475	COG0077	Prephenate dehydratase
MY04_RS08495	COG2205	protein histidine kinase activity
MY04_RS08495	COG0784	Response regulator, receiver
MY04_RS08500	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MY04_RS08510	COG4251	negative regulation of phosphorylation
MY04_RS08520	COG0494	nUDIX hydrolase
MY04_RS08540	COG0175	sulfate reduction
MY04_RS08545	COG0529	Catalyzes the synthesis of activated sulfate
MY04_RS08555	COG4191	Histidine kinase
MY04_RS08555	COG2205	protein histidine kinase activity
MY04_RS08555	COG0745	RESPONSE REGULATOR receiver
MY04_RS08560	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MY04_RS08565	COG0668	transmembrane transport
MY04_RS08575	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MY04_RS08590	COG0303	'Molybdopterin
MY04_RS08595	COG0315	cyclic pyranopterin monophosphate synthase activity
MY04_RS08600	COG0315	cyclic pyranopterin monophosphate synthase activity
MY04_RS08600	COG0746	molybdenum cofactor guanylyltransferase activity
MY04_RS08625	COG1648	precorrin-2 dehydrogenase activity
MY04_RS08625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MY04_RS08630	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MY04_RS08645	COG1595	DNA-templated transcription, initiation
MY04_RS08660	COG4585	Histidine kinase
MY04_RS08665	COG2197	response regulator
MY04_RS08670	COG0243	molybdopterin cofactor binding
MY04_RS08685	COG0314	molybdopterin synthase activity
MY04_RS08695	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MY04_RS08700	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MY04_RS08705	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MY04_RS08710	COG1805	sodium ion transport
MY04_RS08715	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MY04_RS08750	COG0243	molybdopterin cofactor binding
MY04_RS08760	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MY04_RS08785	COG0501	Belongs to the peptidase M48B family
MY04_RS08790	COG1959	2 iron, 2 sulfur cluster binding
MY04_RS08800	COG2319	Wd-40 repeat
MY04_RS08800	COG4249	Peptidase C14 caspase catalytic subunit p20
MY04_RS08810	COG0009	L-threonylcarbamoyladenylate synthase
MY04_RS08815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MY04_RS08815	COG0784	Response regulator, receiver
MY04_RS08815	COG2205	protein histidine kinase activity
MY04_RS08815	COG2198	Histidine kinase
MY04_RS08825	COG0166	Belongs to the GPI family
MY04_RS08835	COG2204	response regulator
MY04_RS08860	COG0116	Belongs to the methyltransferase superfamily
MY04_RS08875	COG0497	DNA recombination
MY04_RS08885	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MY04_RS08890	COG1366	Belongs to the anti-sigma-factor antagonist family
MY04_RS08895	COG1234	tRNA 3'-trailer cleavage
MY04_RS08915	COG1322	Protein conserved in bacteria
MY04_RS08940	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MY04_RS08945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MY04_RS08950	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MY04_RS08955	COG0772	Belongs to the SEDS family
MY04_RS08970	COG1858	cytochrome C peroxidase
MY04_RS08975	COG2824	Alkylphosphonate utilization operon protein PhnA
MY04_RS08990	COG0793	Belongs to the peptidase S41A family
MY04_RS09000	COG0784	Response regulator, receiver
MY04_RS09000	COG2205	protein histidine kinase activity
MY04_RS09010	COG1032	radical SAM domain protein
MY04_RS09020	COG3682	Transcriptional regulator
MY04_RS09055	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MY04_RS09075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MY04_RS09130	COG3022	response to hydroperoxide
MY04_RS09135	COG1054	Belongs to the UPF0176 family
MY04_RS09140	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MY04_RS09150	COG1902	pentaerythritol trinitrate reductase activity
MY04_RS09155	COG1917	Cupin 2, conserved barrel domain protein
MY04_RS09155	COG2169	Transcriptional regulator
MY04_RS09160	COG5002	protein histidine kinase activity
MY04_RS09165	COG0719	Fe-S assembly protein
MY04_RS09170	COG3361	conserved protein (COG2071)
MY04_RS09175	COG0346	lactoylglutathione lyase activity
MY04_RS09200	COG3959	Transketolase, thiamine diphosphate binding domain
MY04_RS09205	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MY04_RS09210	COG1215	transferase activity, transferring glycosyl groups
MY04_RS09220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MY04_RS09225	COG2208	phosphoserine phosphatase activity
MY04_RS09230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MY04_RS09240	COG2045	Belongs to the ComB family
MY04_RS09245	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MY04_RS09250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MY04_RS09255	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MY04_RS09285	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MY04_RS09290	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MY04_RS09295	COG1496	oxidoreductase activity
MY04_RS09345	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MY04_RS09350	COG0280	phosphate acetyltransferase
MY04_RS09350	COG0281	malic enzyme
MY04_RS09370	COG1288	antiporter activity
MY04_RS09385	COG1522	sequence-specific DNA binding
MY04_RS09395	COG0450	alkyl hydroperoxide reductase
MY04_RS09405	COG0300	oxidoreductase activity
MY04_RS09420	COG1619	proteins homologs of microcin C7 resistance protein MccF
MY04_RS09425	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MY04_RS09445	COG2153	protein acetylation
MY04_RS09465	COG0667	Aldo Keto reductase
MY04_RS09470	COG3119	arylsulfatase activity
MY04_RS09480	COG1116	anion transmembrane transporter activity
MY04_RS09485	COG1116	anion transmembrane transporter activity
MY04_RS09485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MY04_RS09490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MY04_RS09495	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MY04_RS09495	COG1116	anion transmembrane transporter activity
MY04_RS09510	COG0004	ammonium transporteR
MY04_RS09525	COG0579	oxidoreductase
MY04_RS09535	COG0779	Required for maturation of 30S ribosomal subunits
MY04_RS09540	COG0195	Participates in both transcription termination and antitermination
MY04_RS09545	COG5180	pathogenesis
MY04_RS09545	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MY04_RS09560	COG1131	(ABC) transporter
MY04_RS09575	COG1472	Belongs to the glycosyl hydrolase 3 family
MY04_RS09590	COG4771	TonB-dependent receptor
MY04_RS09600	COG0316	Belongs to the HesB IscA family
MY04_RS09605	COG0339	signal peptide processing
MY04_RS09610	COG1678	Uncharacterized ACR, COG1678
MY04_RS09625	COG0492	ferredoxin-NADP+ reductase activity
MY04_RS09650	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MY04_RS09650	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MY04_RS09660	COG0519	Catalyzes the synthesis of GMP from XMP
MY04_RS09660	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MY04_RS09675	COG1272	protein, Hemolysin III
MY04_RS09685	COG2871	sodium ion transport
MY04_RS09695	COG1668	transmembrane transport
MY04_RS09700	COG4152	abc transporter atp-binding protein
MY04_RS09715	COG0564	pseudouridine synthase activity
MY04_RS09735	COG3590	peptidase
MY04_RS09745	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MY04_RS09750	COG0436	Aminotransferase
MY04_RS09765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MY04_RS09800	COG0408	coproporphyrinogen oxidase activity
MY04_RS09815	COG0534	Mate efflux family protein
MY04_RS09820	COG3657	addiction module killer protein
MY04_RS09830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MY04_RS09840	COG0285	dihydrofolate synthase activity
MY04_RS09845	COG4912	Dna alkylation repair
MY04_RS09850	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MY04_RS09850	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MY04_RS09855	COG0564	pseudouridine synthase activity
MY04_RS09875	COG0484	heat shock protein binding
MY04_RS09890	COG1045	serine acetyltransferase
MY04_RS09900	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MY04_RS09930	COG2885	chlorophyll binding
MY04_RS09945	COG2706	6-phosphogluconolactonase activity
MY04_RS09975	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MY04_RS10000	COG4974	Belongs to the 'phage' integrase family
MY04_RS10025	COG0140	phosphoribosyl-ATP diphosphatase activity
MY04_RS10025	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MY04_RS10065	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MY04_RS10070	COG3177	Filamentation induced by cAMP protein fic
MY04_RS10125	COG0513	Belongs to the DEAD box helicase family
MY04_RS10130	COG4895	conserved protein (DUF2196)
MY04_RS10140	COG1047	Peptidyl-prolyl cis-trans
MY04_RS10160	COG0534	Mate efflux family protein
MY04_RS10180	COG2249	NAD(P)H dehydrogenase (quinone) activity
MY04_RS10185	COG1858	cytochrome C peroxidase
MY04_RS10205	COG0513	Belongs to the DEAD box helicase family
MY04_RS10235	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MY04_RS10245	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MY04_RS10250	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MY04_RS10255	COG0137	argininosuccinate synthase activity
MY04_RS10265	COG1523	belongs to the glycosyl hydrolase 13 family
MY04_RS10270	COG0431	NADPH-dependent FMN reductase
MY04_RS10290	COG0811	peptide transport
MY04_RS10295	COG0252	asparaginase activity
MY04_RS10300	COG0084	hydrolase, TatD family'
MY04_RS10310	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MY04_RS10315	COG0601	transmembrane transport
MY04_RS10330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MY04_RS10335	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MY04_RS10350	COG1181	Belongs to the D-alanine--D-alanine ligase family
MY04_RS10360	COG2234	aminopeptidase activity
MY04_RS10370	COG0386	Belongs to the glutathione peroxidase family
MY04_RS10400	COG1418	mRNA catabolic process
MY04_RS10420	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MY04_RS10425	COG1187	pseudouridine synthase activity
MY04_RS10445	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MY04_RS10460	COG0633	Ferredoxin
MY04_RS10465	COG2124	cytochrome p450
MY04_RS10470	COG1073	alpha beta
MY04_RS10515	COG0488	(ABC) transporter
MY04_RS10520	COG0523	cobalamin synthesis protein
MY04_RS10565	COG0784	Response regulator, receiver
MY04_RS10570	COG4251	negative regulation of phosphorylation
MY04_RS10585	COG1228	amidohydrolase
MY04_RS10615	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MY04_RS10635	COG0457	Tetratricopeptide repeat
MY04_RS10665	COG5002	protein histidine kinase activity
MY04_RS10690	COG0583	DNA-binding transcription factor activity
MY04_RS10695	COG2855	membrane
MY04_RS10705	COG0432	Pfam Uncharacterised protein family UPF0047
MY04_RS10715	COG0326	Molecular chaperone. Has ATPase activity
MY04_RS10720	COG0513	Belongs to the DEAD box helicase family
MY04_RS10745	COG0126	phosphoglycerate kinase activity
MY04_RS10750	COG1028	Short-chain dehydrogenase reductase Sdr
MY04_RS10765	COG3119	arylsulfatase activity
MY04_RS10775	COG3119	arylsulfatase activity
MY04_RS10785	COG3119	arylsulfatase activity
MY04_RS10790	COG3119	arylsulfatase activity
MY04_RS10800	COG1477	protein flavinylation
MY04_RS10830	COG2223	nitrite transmembrane transporter activity
MY04_RS10850	COG4251	negative regulation of phosphorylation
MY04_RS10855	COG2201	protein-glutamate methylesterase activity
MY04_RS10860	COG4251	negative regulation of phosphorylation
MY04_RS10865	COG4251	negative regulation of phosphorylation
MY04_RS10875	COG1741	Belongs to the pirin family
MY04_RS10900	COG0653	protein targeting
MY04_RS10915	COG1472	Belongs to the glycosyl hydrolase 3 family
MY04_RS10925	COG1704	LemA family
MY04_RS10940	COG0561	phosphatase activity
MY04_RS10955	COG1695	Transcriptional regulator
MY04_RS11055	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MY04_RS11055	COG2070	2-Nitropropane dioxygenase
MY04_RS11060	COG3321	synthase
MY04_RS11060	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MY04_RS11060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MY04_RS11065	COG0604	alcohol dehydrogenase
MY04_RS11065	COG3321	synthase
MY04_RS11095	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MY04_RS11315	COG1328	CTP reductase activity
MY04_RS11315	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MY04_RS11320	COG4251	negative regulation of phosphorylation
MY04_RS11350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MY04_RS11355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MY04_RS11360	COG0571	ribonuclease III activity
MY04_RS11365	COG0791	NLP P60 protein
MY04_RS11385	COG1739	Uncharacterized protein family UPF0029
MY04_RS11400	COG0671	phosphoesterase, PA-phosphatase related
MY04_RS11415	COG4372	Transposase
MY04_RS11420	COG4372	Transposase
MY04_RS11455	COG0481	GTPase activity
MY04_RS11475	COG3459	Glycosyltransferase 36 associated
MY04_RS11480	COG2211	Major facilitator Superfamily
MY04_RS11490	COG1472	Belongs to the glycosyl hydrolase 3 family
MY04_RS11495	COG0702	epimerase
MY04_RS11500	COG4771	TonB-dependent receptor
MY04_RS11520	COG2890	protein-(glutamine-N5) methyltransferase activity
MY04_RS11550	COG1597	lipid kinase activity
MY04_RS11570	COG1368	sulfuric ester hydrolase activity
MY04_RS11575	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MY04_RS11580	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MY04_RS11585	COG2183	response to ionizing radiation
MY04_RS11590	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MY04_RS11605	COG0233	cytoplasmic translational termination
MY04_RS11610	COG0528	UMP kinase activity
MY04_RS11625	COG3850	Histidine kinase
MY04_RS11625	COG5002	protein histidine kinase activity
MY04_RS11630	COG2197	response regulator
MY04_RS11640	COG3341	Caulimovirus viroplasmin
MY04_RS11640	COG0328	RNA-DNA hybrid ribonuclease activity
MY04_RS11645	COG2326	polyphosphate kinase activity
MY04_RS11690	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MY04_RS11710	COG4251	negative regulation of phosphorylation
MY04_RS11715	COG0784	Response regulator, receiver
MY04_RS11720	COG0784	Response regulator, receiver
MY04_RS11720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MY04_RS11720	COG2198	Histidine kinase
MY04_RS11720	COG2205	protein histidine kinase activity
MY04_RS11725	COG0745	RESPONSE REGULATOR receiver
MY04_RS11730	COG0514	ATP-dependent DNA helicase (RecQ)
MY04_RS11735	COG0339	signal peptide processing
MY04_RS11740	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MY04_RS11750	COG2267	carboxylic ester hydrolase activity
MY04_RS11760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MY04_RS11770	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MY04_RS11800	COG1515	deoxyribonuclease V activity
MY04_RS11815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MY04_RS11825	COG2182	Extracellular solute-binding protein
MY04_RS11830	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MY04_RS11835	COG1063	alcohol dehydrogenase
MY04_RS11840	COG1028	Short-chain dehydrogenase reductase Sdr
MY04_RS11870	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MY04_RS11895	COG1012	belongs to the aldehyde dehydrogenase family
MY04_RS11905	COG0148	phosphopyruvate hydratase activity
MY04_RS11925	COG0352	thiamine-phosphate diphosphorylase activity
MY04_RS11925	COG0351	phosphomethylpyrimidine kinase
MY04_RS11930	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MY04_RS11930	COG0352	thiamine-phosphate diphosphorylase activity
MY04_RS11930	COG0351	phosphomethylpyrimidine kinase
MY04_RS11945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MY04_RS11955	COG1012	belongs to the aldehyde dehydrogenase family
MY04_RS11960	COG1024	Enoyl-CoA hydratase
MY04_RS12010	COG1404	Belongs to the peptidase S8 family
MY04_RS12015	COG0006	proline dipeptidase activity
MY04_RS12030	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MY04_RS12035	COG0489	protein tyrosine kinase activity
MY04_RS12045	COG0366	Alpha amylase catalytic
MY04_RS12050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MY04_RS12060	COG2115	Belongs to the xylose isomerase family
MY04_RS12080	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MY04_RS12105	COG1138	Cytochrome C-type biogenesis protein
MY04_RS12155	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MY04_RS12165	COG4953	penicillin-binding protein 1C
MY04_RS12170	COG3263	regulation of cellular component size
MY04_RS12175	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MY04_RS12220	COG0437	4 iron, 4 sulfur cluster binding
MY04_RS12235	COG1607	acyl-coa hydrolase
MY04_RS12240	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MY04_RS12255	COG0116	Belongs to the methyltransferase superfamily
MY04_RS12255	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MY04_RS12265	COG0280	phosphate acetyltransferase
MY04_RS12290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MY04_RS12295	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MY04_RS12310	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MY04_RS12310	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MY04_RS12315	COG2363	Small membrane protein
MY04_RS12330	COG4771	TonB-dependent receptor
MY04_RS12340	COG1472	Belongs to the glycosyl hydrolase 3 family
MY04_RS12390	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MY04_RS12400	COG0477	Major facilitator Superfamily
MY04_RS12410	COG0019	diaminopimelate decarboxylase activity
MY04_RS12425	COG0590	tRNA wobble adenosine to inosine editing
MY04_RS12430	COG1028	Short-chain dehydrogenase reductase Sdr
MY04_RS12515	COG0450	alkyl hydroperoxide reductase
MY04_RS12520	COG0450	alkyl hydroperoxide reductase
MY04_RS12525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MY04_RS12525	COG2207	Transcriptional regulator
MY04_RS12550	COG0069	glutamate synthase activity
MY04_RS12600	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MY04_RS12635	COG0346	lactoylglutathione lyase activity
MY04_RS12680	COG1063	alcohol dehydrogenase
MY04_RS12695	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MY04_RS12705	COG1609	Transcriptional regulator
MY04_RS12725	COG4771	TonB-dependent receptor
MY04_RS12730	COG0800	Aldolase
MY04_RS12745	COG1028	Short-chain dehydrogenase reductase Sdr
MY04_RS12750	COG2271	Major facilitator Superfamily
MY04_RS12775	COG1902	pentaerythritol trinitrate reductase activity
MY04_RS12790	COG1278	Cold shock
MY04_RS12810	COG2755	lipolytic protein G-D-S-L family
MY04_RS12810	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MY04_RS12815	COG1216	Glycosyl transferase, family 2
MY04_RS12815	COG1442	glycosyl transferase family 8
MY04_RS12840	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MY04_RS12855	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MY04_RS12890	COG1418	mRNA catabolic process
MY04_RS12905	COG1082	Xylose isomerase domain protein TIM barrel
MY04_RS12915	COG0366	Alpha amylase catalytic
MY04_RS12915	COG1874	Beta-galactosidase
MY04_RS12920	COG0659	secondary active sulfate transmembrane transporter activity
MY04_RS12925	COG3590	peptidase
MY04_RS12985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MY04_RS12990	COG1011	Hydrolase
MY04_RS12995	COG0508	dehydrogenase complex catalyzes the overall conversion of
MY04_RS13015	COG0159	tryptophan synthase activity
MY04_RS13020	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MY04_RS13030	COG2885	chlorophyll binding
MY04_RS13050	COG0123	including yeast histone deacetylase and acetoin utilization protein
MY04_RS13055	COG1283	sodium-dependent phosphate transmembrane transporter activity
MY04_RS13060	COG0825	malonyl-CoA metabolic process
MY04_RS13085	COG1595	DNA-templated transcription, initiation
MY04_RS13090	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MY04_RS13125	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MY04_RS13130	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MY04_RS13135	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MY04_RS13140	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MY04_RS13145	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MY04_RS13150	COG0356	it plays a direct role in the translocation of protons across the membrane
MY04_RS13165	COG4942	peptidase
MY04_RS13175	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MY04_RS13205	COG1629	transport
MY04_RS13210	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MY04_RS13220	COG0612	Peptidase, M16
MY04_RS13225	COG2255	four-way junction helicase activity
MY04_RS13235	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MY04_RS13240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MY04_RS13255	COG0561	phosphatase activity
MY04_RS13260	COG1629	transport
MY04_RS13275	COG1501	Belongs to the glycosyl hydrolase 31 family
MY04_RS13280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MY04_RS13285	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MY04_RS13315	COG5002	protein histidine kinase activity
MY04_RS13320	COG0826	peptidase U32
MY04_RS13345	COG2860	membrane
MY04_RS13350	COG0523	cobalamin synthesis protein
MY04_RS13355	COG1228	amidohydrolase
MY04_RS13395	COG0668	transmembrane transport
MY04_RS13400	COG0668	transmembrane transport
MY04_RS13405	COG2198	Histidine kinase
MY04_RS13405	COG0784	Response regulator, receiver
MY04_RS13405	COG5002	protein histidine kinase activity
MY04_RS13425	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MY04_RS13440	COG0358	DNA primase activity
MY04_RS13445	COG0175	sulfate reduction
MY04_RS13470	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MY04_RS13475	COG1388	LysM domain
MY04_RS13475	COG0791	NLP P60 protein
MY04_RS13480	COG0154	amidase activity
MY04_RS13485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MY04_RS13490	COG1132	(ABC) transporter
MY04_RS13505	COG5520	Belongs to the glycosyl hydrolase 30 family
MY04_RS13510	COG5520	Belongs to the glycosyl hydrolase 30 family
MY04_RS13520	COG0702	epimerase
MY04_RS13525	COG4771	TonB-dependent receptor
MY04_RS13535	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MY04_RS13550	COG0575	Belongs to the CDS family
MY04_RS13565	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MY04_RS13595	COG1702	phosphate starvation-inducible protein PhoH
MY04_RS13610	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MY04_RS13615	COG4974	Belongs to the 'phage' integrase family
MY04_RS13640	COG4591	ABC-type transport system involved in lipoprotein release permease component
MY04_RS13645	COG1473	amidohydrolase
MY04_RS13650	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MY04_RS13655	COG0484	heat shock protein binding
MY04_RS13675	COG1983	PspC domain protein
MY04_RS13680	COG1960	acyl-CoA dehydrogenase activity
MY04_RS13685	COG2234	aminopeptidase activity
MY04_RS13695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MY04_RS13710	COG2860	membrane
MY04_RS13755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MY04_RS13765	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MY04_RS13765	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MY04_RS13770	COG0750	zinc metalloprotease
MY04_RS13775	COG0572	uridine kinase
MY04_RS13780	COG0569	domain protein
MY04_RS13785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MY04_RS13790	COG1595	DNA-templated transcription, initiation
MY04_RS13820	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MY04_RS13830	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MY04_RS13835	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MY04_RS13860	COG0584	glycerophosphoryl diester phosphodiesterase
MY04_RS13905	COG0471	metal ion transport
MY04_RS13905	COG3273	potassium ion transport
MY04_RS13910	COG0730	response to heat
MY04_RS13935	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MY04_RS13975	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MY04_RS13985	COG0351	phosphomethylpyrimidine kinase
MY04_RS13990	COG0352	thiamine-phosphate diphosphorylase activity
MY04_RS13995	COG2022	thiamine diphosphate biosynthetic process
MY04_RS14000	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MY04_RS14005	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MY04_RS14015	COG0463	Glycosyl transferase, family 2
MY04_RS14020	COG0562	UDP-galactopyranose mutase
MY04_RS14055	COG1132	(ABC) transporter
MY04_RS14060	COG0702	epimerase
MY04_RS14095	COG0183	Belongs to the thiolase family
MY04_RS14100	COG1250	3-hydroxyacyl-CoA dehydrogenase
MY04_RS14100	COG1024	Enoyl-CoA hydratase
MY04_RS14110	COG1132	(ABC) transporter
MY04_RS14120	COG0563	adenylate kinase activity
MY04_RS14125	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MY04_RS14130	COG0783	Belongs to the Dps family
MY04_RS14160	COG2208	phosphoserine phosphatase activity
MY04_RS14170	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MY04_RS14200	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MY04_RS14205	COG1984	allophanate hydrolase subunit 2
MY04_RS14210	COG1012	belongs to the aldehyde dehydrogenase family
MY04_RS14220	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MY04_RS14255	COG0482	sulfurtransferase activity
MY04_RS14290	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MY04_RS14295	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MY04_RS14305	COG0463	Glycosyl transferase, family 2
MY04_RS14315	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MY04_RS14370	COG2089	acid synthase
MY04_RS14390	COG2030	dehydratase
MY04_RS14395	COG1083	cytidylyl-transferase
MY04_RS14400	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MY04_RS14405	COG1086	Polysaccharide biosynthesis protein
MY04_RS14435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MY04_RS14440	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MY04_RS14445	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
MY04_RS14445	COG0662	Cupin 2, conserved barrel domain protein
MY04_RS14455	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MY04_RS14475	COG2755	lipolytic protein G-D-S-L family
MY04_RS14510	COG1956	GAF domain-containing protein
MY04_RS14515	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MY04_RS14540	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MY04_RS14555	COG0071	Belongs to the small heat shock protein (HSP20) family
MY04_RS14560	COG0071	Belongs to the small heat shock protein (HSP20) family
MY04_RS14575	COG1247	-acetyltransferase
MY04_RS14580	COG0288	reversible hydration of carbon dioxide
MY04_RS14590	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MY04_RS14595	COG2264	protein methyltransferase activity
MY04_RS14610	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MY04_RS14615	COG0784	Response regulator, receiver
MY04_RS14620	COG4251	negative regulation of phosphorylation
MY04_RS14625	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MY04_RS14640	COG2197	response regulator
MY04_RS14660	COG0501	Belongs to the peptidase M48B family
MY04_RS14670	COG3119	arylsulfatase activity
MY04_RS14675	COG1694	Mazg nucleotide pyrophosphohydrolase
MY04_RS14680	COG0702	epimerase
MY04_RS14685	COG0714	Associated with various cellular activities
MY04_RS14705	COG2304	oxidoreductase activity
MY04_RS14725	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MY04_RS14730	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MY04_RS14735	COG0049	tRNA binding
MY04_RS14740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MY04_RS14745	COG0051	transcription antitermination factor activity, RNA binding
MY04_RS14760	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
MY04_RS14765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MY04_RS14765	COG1017	nitric oxide dioxygenase activity
MY04_RS14775	COG2333	competence protein COMEC
MY04_RS14775	COG0658	competence protein
MY04_RS14780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MY04_RS14785	COG1104	cysteine desulfurase activity
MY04_RS14790	COG0438	transferase activity, transferring glycosyl groups
MY04_RS14795	COG3118	belongs to the thioredoxin family
MY04_RS14810	COG3279	Response regulator of the LytR AlgR family
MY04_RS14835	COG1028	Short-chain dehydrogenase reductase Sdr
MY04_RS14845	COG0653	protein targeting
MY04_RS14860	COG0545	Peptidyl-prolyl cis-trans isomerase
MY04_RS14865	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MY04_RS14870	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MY04_RS14880	COG0463	Glycosyl transferase, family 2
MY04_RS14895	COG0745	RESPONSE REGULATOR receiver
MY04_RS14895	COG2205	protein histidine kinase activity
MY04_RS14895	COG3292	Two component regulator propeller
MY04_RS14905	COG4771	TonB-dependent receptor
MY04_RS14915	COG3279	Response regulator of the LytR AlgR family
MY04_RS14965	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MY04_RS14975	COG2239	Acts as a magnesium transporter
MY04_RS14985	COG3279	Response regulator of the LytR AlgR family
MY04_RS14990	COG4067	protein conserved in archaea
MY04_RS14990	COG0189	ligase activity
MY04_RS15010	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MY04_RS15015	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MY04_RS15025	COG0606	chelatase, subunit chli
MY04_RS15065	COG4181	ATPase activity
MY04_RS15085	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MY04_RS15095	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MY04_RS15105	COG3591	Belongs to the peptidase S1B family
MY04_RS15125	COG2273	Hydrolase Family 16
MY04_RS15130	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MY04_RS15135	COG1185	polyribonucleotide nucleotidyltransferase activity
MY04_RS15140	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MY04_RS15155	COG3275	phosphorelay sensor kinase activity
MY04_RS15160	COG3279	Response regulator of the LytR AlgR family
MY04_RS15165	COG1757	Na H antiporter
MY04_RS15175	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MY04_RS15180	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MY04_RS15185	COG0066	3-isopropylmalate dehydratase activity
MY04_RS15215	COG0405	Gamma-glutamyltransferase
MY04_RS15230	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MY04_RS15245	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MY04_RS15250	COG1136	(ABC) transporter
MY04_RS15250	COG0577	efflux transmembrane transporter activity
MY04_RS15265	COG1960	acyl-CoA dehydrogenase activity
MY04_RS15270	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
MY04_RS15270	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MY04_RS15275	COG2312	Erythromycin esterase
MY04_RS15300	COG0501	Belongs to the peptidase M48B family
MY04_RS15305	COG0228	four-way junction DNA binding
MY04_RS15330	COG0629	single-stranded DNA binding
MY04_RS15350	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MY04_RS15365	COG1360	Flagellar Motor Protein
MY04_RS15375	COG2715	membrane protein required for spore maturation
MY04_RS15390	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MY04_RS15395	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MY04_RS15405	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MY04_RS15410	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MY04_RS15440	COG2814	Major facilitator Superfamily
MY04_RS15460	COG2814	Major facilitator Superfamily
MY04_RS15480	COG1846	Transcriptional regulator
MY04_RS15485	COG1115	amino acid carrier protein
MY04_RS15520	COG0542	response to heat
MY04_RS15545	COG2255	four-way junction helicase activity
MY04_RS15570	COG1595	DNA-templated transcription, initiation
MY04_RS15585	COG1595	DNA-templated transcription, initiation
MY04_RS15595	COG2373	Large extracellular alpha-helical protein
MY04_RS15610	COG0488	(ABC) transporter
MY04_RS15615	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MY04_RS15620	COG2154	pterin-4-alpha-carbinolamine dehydratase
MY04_RS15630	COG0138	bifunctional purine biosynthesis protein purh
MY04_RS15635	COG0237	dephospho-CoA kinase activity
MY04_RS15660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MY04_RS15670	COG1040	competence protein
MY04_RS15680	COG0708	Exodeoxyribonuclease III
MY04_RS15700	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MY04_RS15705	COG0445	tRNA wobble uridine modification
MY04_RS15725	COG4682	membrane
MY04_RS15735	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MY04_RS15735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MY04_RS15775	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MY04_RS15830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MY04_RS15835	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MY04_RS15850	COG1629	transport
MY04_RS15850	COG4206	TonB-dependent receptor
MY04_RS15875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MY04_RS15905	COG1136	(ABC) transporter
MY04_RS15920	COG1131	(ABC) transporter
MY04_RS15930	COG1725	Transcriptional regulator
MY04_RS15945	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MY04_RS15950	COG2204	response regulator
MY04_RS15975	COG5002	protein histidine kinase activity
MY04_RS15985	COG1595	DNA-templated transcription, initiation
MY04_RS15990	COG0194	GDP metabolic process
MY04_RS16010	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MY04_RS16035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MY04_RS16040	COG0085	RNA polymerase activity
MY04_RS16050	COG4251	negative regulation of phosphorylation
MY04_RS16055	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MY04_RS16055	COG1796	DNA polymerase
MY04_RS16060	COG1028	Short-chain dehydrogenase reductase Sdr
MY04_RS16065	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MY04_RS16070	COG0564	pseudouridine synthase activity
MY04_RS16130	COG1809	phosphosulfolactate synthase activity
MY04_RS16140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MY04_RS16175	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MY04_RS16195	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MY04_RS16200	COG0514	ATP-dependent DNA helicase (RecQ)
MY04_RS16205	COG2201	protein-glutamate methylesterase activity
MY04_RS16235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MY04_RS16250	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MY04_RS16265	COG4206	TonB-dependent receptor
MY04_RS16265	COG1629	transport
MY04_RS16285	COG0366	Alpha amylase catalytic
MY04_RS16285	COG1874	Beta-galactosidase
MY04_RS16315	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MY04_RS16325	COG3951	Flagellar rod assembly protein muramidase FlgJ
MY04_RS16325	COG1705	Flagellar rod assembly protein muramidase FlgJ
MY04_RS16335	COG1136	(ABC) transporter
MY04_RS16370	COG3507	Belongs to the glycosyl hydrolase 43 family
MY04_RS16370	COG2382	esterase
MY04_RS16370	COG3693	PFAM glycoside hydrolase, family 10
MY04_RS16375	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MY04_RS16380	COG0557	exoribonuclease II activity
MY04_RS16390	COG0295	cytidine deaminase activity
MY04_RS16400	COG1490	D-aminoacyl-tRNA deacylase activity
MY04_RS16420	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MY04_RS16440	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MY04_RS16450	COG0052	Belongs to the universal ribosomal protein uS2 family
MY04_RS16455	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MY04_RS16460	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MY04_RS16470	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MY04_RS16485	COG0254	rRNA binding
MY04_RS16505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MY04_RS16525	COG3118	belongs to the thioredoxin family
MY04_RS16555	COG2095	MarC family integral membrane protein
MY04_RS16565	COG0527	aspartate kinase activity
MY04_RS16565	COG0460	homoserine dehydrogenase
MY04_RS16570	COG0083	homoserine kinase activity
MY04_RS16590	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MY04_RS16590	COG4651	solute:proton antiporter activity
MY04_RS16605	COG1022	Amp-dependent synthetase and ligase
MY04_RS16610	COG2264	protein methyltransferase activity
MY04_RS16630	COG1733	regulation of RNA biosynthetic process
MY04_RS16635	COG0778	Nitroreductase
MY04_RS16645	COG0456	acetyltransferase
MY04_RS16650	COG3291	Pkd domain containing protein
MY04_RS16655	COG1629	transport
MY04_RS16685	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MY04_RS16715	COG0149	triose-phosphate isomerase activity
MY04_RS16730	COG1228	amidohydrolase
MY04_RS16740	COG1090	epimerase
MY04_RS16745	COG4206	TonB-dependent receptor
MY04_RS16745	COG1629	transport
MY04_RS16755	COG4206	TonB-dependent receptor
MY04_RS16755	COG1629	transport
MY04_RS16765	COG1629	transport
MY04_RS16765	COG4206	TonB-dependent receptor
MY04_RS16775	COG1629	transport
MY04_RS16810	COG0519	Catalyzes the synthesis of GMP from XMP
MY04_RS16810	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MY04_RS16880	COG4372	Transposase
MY04_RS16890	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MY04_RS16895	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MY04_RS16900	COG0181	hydroxymethylbilane synthase activity
MY04_RS16905	COG0640	Transcriptional regulator
MY04_RS16920	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MY04_RS16930	COG0009	L-threonylcarbamoyladenylate synthase
MY04_RS16945	COG0321	lipoyl(octanoyl) transferase activity
MY04_RS16950	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MY04_RS16955	COG2095	MarC family integral membrane protein
MY04_RS16965	COG0131	Imidazoleglycerol-phosphate dehydratase
MY04_RS16985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MY04_RS16990	COG0322	excinuclease ABC activity
MY04_RS17000	COG4989	oxidoreductase activity
MY04_RS17005	COG3852	Histidine kinase
MY04_RS17030	COG0776	regulation of translation
MY04_RS17040	COG1530	ribonuclease E activity
MY04_RS17045	COG3118	belongs to the thioredoxin family
MY04_RS17060	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MY04_RS17070	COG0509	glycine decarboxylation via glycine cleavage system
MY04_RS17075	COG1051	belongs to the nudix hydrolase family
MY04_RS17125	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MY04_RS17130	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MY04_RS17135	COG0552	protein localization to endoplasmic reticulum
MY04_RS17145	COG0205	6-phosphofructokinase activity
MY04_RS17150	COG0659	secondary active sulfate transmembrane transporter activity
MY04_RS17170	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MY04_RS17205	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MY04_RS17235	COG0542	response to heat
MY04_RS17245	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MY04_RS17250	COG1192	Involved in chromosome partitioning
MY04_RS17260	COG2954	triphosphatase activity
MY04_RS17265	COG0626	cystathionine gamma-synthase activity
MY04_RS17280	COG1611	Belongs to the LOG family
MY04_RS17285	COG0741	lytic transglycosylase activity
MY04_RS17285	COG1388	LysM domain
MY04_RS17290	COG1160	GTP binding
MY04_RS17300	COG2234	aminopeptidase activity
MY04_RS17315	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MY04_RS17325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MY04_RS17330	COG1940	carbohydrate kinase activity
MY04_RS17340	COG1940	carbohydrate kinase activity
MY04_RS17350	COG1629	transport
MY04_RS17365	COG0793	Belongs to the peptidase S41A family
MY04_RS17370	COG3264	Mechanosensitive ion channel
MY04_RS17370	COG1511	domain protein
MY04_RS17415	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MY04_RS17450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MY04_RS17460	COG1428	Deoxynucleoside kinase
MY04_RS17465	COG1428	Deoxynucleoside kinase
MY04_RS17470	COG0572	uridine kinase
MY04_RS17475	COG0594	ribonuclease P activity
MY04_RS17485	COG2425	protein containing a von Willebrand factor type A (vWA) domain
MY04_RS17490	COG0714	Associated with various cellular activities
MY04_RS17500	COG1609	Transcriptional regulator
MY04_RS17510	COG1028	Short-chain dehydrogenase reductase Sdr
MY04_RS17520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MY04_RS17555	COG4677	pectinesterase activity
MY04_RS17565	COG1028	Short-chain dehydrogenase reductase Sdr
MY04_RS17570	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MY04_RS17585	COG0802	atpase or kinase
MY04_RS17595	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MY04_RS17615	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MY04_RS17625	COG2814	Major facilitator Superfamily
MY04_RS17630	COG3507	Belongs to the glycosyl hydrolase 43 family
MY04_RS17635	COG4771	TonB-dependent receptor
MY04_RS17655	COG0300	oxidoreductase activity
MY04_RS17680	COG2115	Belongs to the xylose isomerase family
MY04_RS17685	COG2814	Major facilitator Superfamily
MY04_RS17685	COG0477	Major facilitator Superfamily
MY04_RS17695	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MY04_RS17700	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MY04_RS17725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MY04_RS17740	COG0443	Heat shock 70 kDa protein
MY04_RS17750	COG0686	Belongs to the AlaDH PNT family
MY04_RS17800	COG2226	methyltransferase
MY04_RS17805	COG2885	chlorophyll binding
MY04_RS17820	COG2151	metal-sulfur cluster biosynthetic enzyme
MY04_RS17825	COG2166	iron-sulfur cluster assembly
MY04_RS17830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MY04_RS17850	COG1136	(ABC) transporter
MY04_RS17855	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MY04_RS17865	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MY04_RS17870	COG0134	indole-3-glycerol-phosphate synthase activity
MY04_RS17885	COG0135	phosphoribosylanthranilate isomerase activity
MY04_RS17890	COG0133	tryptophan synthase activity
MY04_RS17900	COG3613	nucleoside 2-deoxyribosyltransferase
MY04_RS17935	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MY04_RS17940	COG1917	Cupin 2, conserved barrel domain protein
MY04_RS17940	COG4977	sequence-specific DNA binding
MY04_RS17980	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MY04_RS18000	COG2814	Major facilitator Superfamily
MY04_RS18005	COG1649	PFAM Uncharacterised BCR, COG1649
MY04_RS18030	COG1162	GTPase activity
MY04_RS18035	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MY04_RS18105	COG0346	lactoylglutathione lyase activity
MY04_RS18120	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
MY04_RS18125	COG1979	alcohol dehydrogenase
MY04_RS18130	COG0300	oxidoreductase activity
MY04_RS18140	COG0643	Histidine kinase
MY04_RS18140	COG0784	Response regulator, receiver
MY04_RS18140	COG2198	Histidine kinase
MY04_RS18150	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MY04_RS18155	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MY04_RS18155	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MY04_RS18160	COG0436	Aminotransferase
MY04_RS18180	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MY04_RS18185	COG1192	Involved in chromosome partitioning
MY04_RS18195	COG0835	chemotaxis
MY04_RS18200	COG2201	protein-glutamate methylesterase activity
MY04_RS18205	COG0643	Histidine kinase
MY04_RS18205	COG2198	Histidine kinase
MY04_RS18220	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MY04_RS18225	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MY04_RS18230	COG0714	Associated with various cellular activities
MY04_RS18255	COG1476	TRANSCRIPTIONal
MY04_RS18285	COG3956	TIGRFAM MazG family protein
MY04_RS18295	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MY04_RS18310	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MY04_RS18315	COG0255	Belongs to the universal ribosomal protein uL29 family
MY04_RS18320	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MY04_RS18325	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MY04_RS18330	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MY04_RS18335	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MY04_RS18340	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MY04_RS18345	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MY04_RS18350	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MY04_RS18355	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MY04_RS18360	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MY04_RS18365	COG1841	ribosomal large subunit assembly
MY04_RS18370	COG0200	Binds to the 23S rRNA
MY04_RS18375	COG0201	protein transport
MY04_RS18385	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MY04_RS18390	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MY04_RS18395	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MY04_RS18400	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MY04_RS18405	COG0202	RNA polymerase activity
MY04_RS18410	COG0203	ribosomal protein L17
MY04_RS18415	COG0505	Belongs to the CarA family
MY04_RS18430	COG0612	Peptidase, M16
MY04_RS18445	COG0222	ribosome binding
MY04_RS18450	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MY04_RS18455	COG0081	regulation of translation
MY04_RS18460	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MY04_RS18465	COG0250	Participates in transcription elongation, termination and antitermination
MY04_RS18520	COG0191	fructose-bisphosphate aldolase activity
MY04_RS18530	COG0248	Ppx GppA phosphatase
MY04_RS18550	COG0556	nucleotide-excision repair
MY04_RS18560	COG0511	ligase activity, forming carbon-carbon bonds
MY04_RS18565	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
MY04_RS18615	COG0698	ribose 5-phosphate isomerase
MY04_RS18630	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MY04_RS18635	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MY04_RS18640	COG0088	Forms part of the polypeptide exit tunnel
MY04_RS18645	COG0089	rRNA binding
MY04_RS18650	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MY04_RS18655	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MY04_RS18660	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MY04_RS18665	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MY04_RS18670	COG0733	neurotransmitter:sodium symporter activity
MY04_RS18675	COG0423	glycine-tRNA ligase activity
MY04_RS18680	COG3951	Flagellar rod assembly protein muramidase FlgJ
MY04_RS18680	COG1705	Flagellar rod assembly protein muramidase FlgJ
MY04_RS18695	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MY04_RS18710	COG0730	response to heat
MY04_RS18715	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MY04_RS18720	COG0268	Binds directly to 16S ribosomal RNA
MY04_RS18730	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MY04_RS18740	COG0442	prolyl-tRNA aminoacylation
MY04_RS18755	COG1078	dGTPase activity
MY04_RS18760	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MY04_RS18765	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MY04_RS18765	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MY04_RS18770	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MY04_RS18775	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MY04_RS18785	COG1301	dicarboxylic acid transport
MY04_RS18825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MY04_RS18860	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MY04_RS18870	COG0193	aminoacyl-tRNA hydrolase activity
MY04_RS18880	COG0596	Alpha beta hydrolase
MY04_RS18890	COG3876	Protein conserved in bacteria
MY04_RS18895	COG0363	glucosamine-6-phosphate deaminase activity
MY04_RS18900	COG4535	Mg2 and Co2 transporter CorC
MY04_RS18905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MY04_RS18915	COG0336	Belongs to the RNA methyltransferase TrmD family
MY04_RS18920	COG0470	DNA polymerase III
MY04_RS18925	COG0740	serine-type endopeptidase activity
MY04_RS18930	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MY04_RS18935	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MY04_RS18955	COG3119	arylsulfatase activity
MY04_RS18960	COG0667	Aldo Keto reductase
MY04_RS18965	COG0508	dehydrogenase complex catalyzes the overall conversion of
MY04_RS18965	COG0022	dehydrogenase e1 component
MY04_RS18980	COG0101	tRNA pseudouridine synthase activity
MY04_RS19050	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MY04_RS19055	COG1214	PFAM Peptidase M22, glycoprotease
MY04_RS19060	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MY04_RS19075	COG1028	Short-chain dehydrogenase reductase Sdr
MY04_RS19080	COG2195	Cleaves the N-terminal amino acid of tripeptides
MY04_RS19095	COG3119	arylsulfatase activity
MY04_RS19105	COG4585	Histidine kinase
MY04_RS19175	COG0584	glycerophosphoryl diester phosphodiesterase
MY04_RS19195	COG0302	gtp cyclohydrolase
MY04_RS19200	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MY04_RS19245	COG2249	NAD(P)H dehydrogenase (quinone) activity
MY04_RS19290	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
MY04_RS19305	COG1032	radical SAM domain protein
MY04_RS19335	COG4206	TonB-dependent receptor
MY04_RS19410	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MY04_RS19420	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MY04_RS19430	COG0739	heme binding
MY04_RS19445	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MY04_RS19455	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MY04_RS19495	COG1127	ABC transporter
MY04_RS19500	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MY04_RS19510	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MY04_RS19525	COG0668	transmembrane transport
MY04_RS19530	COG1216	Glycosyl transferase, family 2
MY04_RS19540	COG2204	response regulator
MY04_RS19555	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MY04_RS19565	COG1231	oxidoreductase activity
MY04_RS19595	COG1192	Involved in chromosome partitioning
MY04_RS19630	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MY04_RS19670	COG2233	PERMEase
MY04_RS19685	COG2205	protein histidine kinase activity
MY04_RS19690	COG1408	metallophosphoesterase
MY04_RS19710	COG2759	Belongs to the formate--tetrahydrofolate ligase family
MY04_RS19715	COG1028	Short-chain dehydrogenase reductase Sdr
MY04_RS19720	COG0583	DNA-binding transcription factor activity
MY04_RS19740	COG0300	oxidoreductase activity
MY04_RS19760	COG1752	Esterase of the alpha-beta hydrolase superfamily
MY04_RS19765	COG2176	DNA-directed DNA polymerase activity
MY04_RS19790	COG0215	cysteine-tRNA ligase activity
MY04_RS19805	COG0277	FAD linked oxidase domain protein
MY04_RS19805	COG0247	lactate metabolic process
MY04_RS19830	COG0302	gtp cyclohydrolase
MY04_RS19850	COG2003	Belongs to the UPF0758 family
MY04_RS19870	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MY04_RS19885	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MY04_RS19890	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MY04_RS19915	COG1774	PSP1 C-terminal conserved region
MY04_RS19920	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MY04_RS19935	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MY04_RS19945	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MY04_RS19960	COG1162	GTPase activity
MY04_RS19970	COG1595	DNA-templated transcription, initiation
MY04_RS19975	COG0300	oxidoreductase activity
MY04_RS19995	COG1293	RNA-binding protein homologous to eukaryotic snRNP
MY04_RS20005	COG1968	undecaprenyl-diphosphatase activity
MY04_RS20010	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MY04_RS20015	COG0196	riboflavin kinase activity
MY04_RS20045	COG0366	Alpha amylase catalytic
MY04_RS20075	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MY04_RS20090	COG3292	Two component regulator propeller
MY04_RS20090	COG3292	Two component regulator propeller
MY04_RS20090	COG2205	protein histidine kinase activity
MY04_RS20090	COG0745	RESPONSE REGULATOR receiver
MY04_RS20090	COG2205	protein histidine kinase activity
MY04_RS20090	COG0745	RESPONSE REGULATOR receiver
MY04_RS20095	COG0702	epimerase
MY04_RS20100	COG4771	TonB-dependent receptor
MY04_RS20135	COG0004	ammonium transporteR
MY04_RS20155	COG0577	efflux transmembrane transporter activity
MY04_RS20155	COG1136	(ABC) transporter
MY04_RS20160	COG1136	(ABC) transporter
MY04_RS20160	COG0577	efflux transmembrane transporter activity
MY04_RS20175	COG0612	Peptidase, M16
MY04_RS20190	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MY04_RS20205	COG3279	Response regulator of the LytR AlgR family
MY04_RS20210	COG2972	Histidine kinase
MY04_RS20220	COG1136	(ABC) transporter
MY04_RS20260	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MY04_RS20265	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MY04_RS21155	COG0105	UTP biosynthetic process
MY04_RS21575	COG1674	ftsk spoiiie
MY04_RS22980	COG4206	TonB-dependent receptor
MY04_RS22980	COG1629	transport
MY04_RS23455	COG4771	TonB-dependent receptor
MY04_RS24035	COG0012	GTP binding
MY04_RS24225	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MY04_RS24625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MY04_RS24865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MY04_RS25355	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MY04_RS25590	COG0047	phosphoribosylformylglycinamidine synthase activity
MY04_RS25590	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MY04_RS25935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MY04_RS26380	COG3250	beta-galactosidase activity
MY04_RS26985	COG1388	LysM domain
MY04_RS26985	COG1705	Flagellar rod assembly protein muramidase FlgJ
MY04_RS27015	COG0070	glutamate synthase
MY04_RS27015	COG0069	glutamate synthase activity
MY04_RS27015	COG0067	glutamate synthase
MY04_RS27245	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MY04_RS27320	COG4206	TonB-dependent receptor
MY04_RS27320	COG1629	transport
MY04_RS27570	COG0784	Response regulator, receiver
MY04_RS27570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MY04_RS27570	COG2198	Histidine kinase
MY04_RS27570	COG2205	protein histidine kinase activity