locus-tag	class	description
HUE47_RS00080	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HUE47_RS00085	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HUE47_RS00090	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HUE47_RS00095	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HUE47_RS00100	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
HUE47_RS00110	COG0305	Participates in initiation and elongation during chromosome replication
HUE47_RS00115	COG0825	malonyl-CoA metabolic process
HUE47_RS00130	COG0343	queuine tRNA-ribosyltransferase activity
HUE47_RS00140	COG3958	Transketolase
HUE47_RS00145	COG0156	8-amino-7-oxononanoate synthase activity
HUE47_RS00155	COG1132	(ABC) transporter
HUE47_RS00165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUE47_RS00175	COG1862	Preprotein translocase
HUE47_RS00230	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUE47_RS00235	COG0542	response to heat
HUE47_RS00240	COG0189	ligase activity
HUE47_RS00240	COG4067	protein conserved in archaea
HUE47_RS00245	COG2323	membrane
HUE47_RS00255	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HUE47_RS00270	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HUE47_RS00290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUE47_RS00315	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUE47_RS00335	COG0531	amino acid
HUE47_RS00340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUE47_RS00350	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HUE47_RS00355	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HUE47_RS00365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUE47_RS00370	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUE47_RS00375	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUE47_RS00380	COG0542	response to heat
HUE47_RS00390	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HUE47_RS00405	COG0259	pyridoxamine-phosphate oxidase activity
HUE47_RS00410	COG1234	tRNA 3'-trailer cleavage
HUE47_RS00420	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HUE47_RS00445	COG0540	Belongs to the ATCase OTCase family
HUE47_RS00450	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HUE47_RS00460	COG2211	Major facilitator Superfamily
HUE47_RS00465	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HUE47_RS00475	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HUE47_RS00480	COG2270	Major facilitator Superfamily
HUE47_RS00495	COG1022	Amp-dependent synthetase and ligase
HUE47_RS00500	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HUE47_RS00505	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUE47_RS00510	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HUE47_RS00515	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUE47_RS00520	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HUE47_RS00520	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HUE47_RS00525	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUE47_RS00530	COG1078	dGTPase activity
HUE47_RS00535	COG3590	peptidase
HUE47_RS00540	COG2204	response regulator
HUE47_RS00545	COG0802	atpase or kinase
HUE47_RS00550	COG0686	Belongs to the AlaDH PNT family
HUE47_RS00565	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HUE47_RS00570	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HUE47_RS00575	COG1505	serine-type exopeptidase activity
HUE47_RS00580	COG4771	TonB-dependent receptor
HUE47_RS00600	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HUE47_RS00610	COG1234	tRNA 3'-trailer cleavage
HUE47_RS00640	COG0306	phosphate transporter
HUE47_RS00650	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUE47_RS00665	COG1252	NADH dehydrogenase
HUE47_RS00675	COG0037	tRNA processing
HUE47_RS00690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUE47_RS00700	COG3956	TIGRFAM MazG family protein
HUE47_RS00710	COG0242	peptide deformylase activity
HUE47_RS00715	COG0579	oxidoreductase
HUE47_RS00720	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HUE47_RS00725	COG2171	N-acyltransferase activity
HUE47_RS00735	COG0463	Glycosyl transferase, family 2
HUE47_RS00745	COG0463	Glycosyl transferase, family 2
HUE47_RS00765	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUE47_RS00775	COG3842	ATPase activity
HUE47_RS00780	COG4977	sequence-specific DNA binding
HUE47_RS00790	COG2885	chlorophyll binding
HUE47_RS00800	COG0326	Molecular chaperone. Has ATPase activity
HUE47_RS00805	COG1278	Cold shock
HUE47_RS00825	COG0784	Response regulator, receiver
HUE47_RS00825	COG2205	protein histidine kinase activity
HUE47_RS00850	COG0277	FAD linked oxidase domain protein
HUE47_RS00870	COG1703	isobutyryl-CoA mutase activity
HUE47_RS00890	COG2304	oxidoreductase activity
HUE47_RS00895	COG0488	(ABC) transporter
HUE47_RS00905	COG0405	Gamma-glutamyltransferase
HUE47_RS00920	COG2204	response regulator
HUE47_RS00925	COG1668	transmembrane transport
HUE47_RS00930	COG4152	abc transporter atp-binding protein
HUE47_RS00935	COG0484	heat shock protein binding
HUE47_RS00940	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HUE47_RS00985	COG1695	Transcriptional regulator
HUE47_RS01025	COG0492	ferredoxin-NADP+ reductase activity
HUE47_RS01030	COG0552	protein localization to endoplasmic reticulum
HUE47_RS01040	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUE47_RS01045	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUE47_RS01050	COG1058	Belongs to the CinA family
HUE47_RS01050	COG1546	Belongs to the CinA family
HUE47_RS01060	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUE47_RS01070	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUE47_RS01085	COG0488	(ABC) transporter
HUE47_RS01100	COG3118	belongs to the thioredoxin family
HUE47_RS01110	COG1136	(ABC) transporter
HUE47_RS01115	COG0612	Peptidase, M16
HUE47_RS01120	COG2096	Adenosyltransferase
HUE47_RS01130	COG0653	protein targeting
HUE47_RS01205	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
HUE47_RS01210	COG0436	Aminotransferase
HUE47_RS01215	COG1192	Involved in chromosome partitioning
HUE47_RS01220	COG1475	DNA binding
HUE47_RS01230	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HUE47_RS01235	COG0681	Belongs to the peptidase S26 family
HUE47_RS01260	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HUE47_RS01265	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HUE47_RS01275	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUE47_RS01280	COG3118	belongs to the thioredoxin family
HUE47_RS01290	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HUE47_RS01295	COG1215	transferase activity, transferring glycosyl groups
HUE47_RS01385	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUE47_RS01395	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUE47_RS01405	COG0336	Belongs to the RNA methyltransferase TrmD family
HUE47_RS01410	COG0300	oxidoreductase activity
HUE47_RS01425	COG0335	large ribosomal subunit rRNA binding
HUE47_RS01455	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUE47_RS01460	COG0517	IMP dehydrogenase activity
HUE47_RS01465	COG3015	lipoprotein NlpE involved in copper resistance
HUE47_RS01490	COG0556	nucleotide-excision repair
HUE47_RS01500	COG0018	arginyl-trna synthetase
HUE47_RS01530	COG4974	Belongs to the 'phage' integrase family
HUE47_RS01555	COG2801	Transposase and inactivated derivatives
HUE47_RS01565	COG2963	transposase activity
HUE47_RS01720	COG1482	cell wall glycoprotein biosynthetic process
HUE47_RS01725	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HUE47_RS01735	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HUE47_RS01740	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
HUE47_RS01775	COG1881	PFAM PEBP family protein
HUE47_RS01795	COG4206	TonB-dependent receptor
HUE47_RS01810	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HUE47_RS01815	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HUE47_RS01825	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
HUE47_RS01840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUE47_RS01845	COG1120	ATPase activity
HUE47_RS01855	COG1187	pseudouridine synthase activity
HUE47_RS01870	COG1322	Protein conserved in bacteria
HUE47_RS01885	COG1607	acyl-coa hydrolase
HUE47_RS01910	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUE47_RS01920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUE47_RS01925	COG0038	chloride channel
HUE47_RS01930	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUE47_RS01935	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HUE47_RS01970	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUE47_RS01975	COG1027	Aspartate ammonia-lyase
HUE47_RS01985	COG0254	rRNA binding
HUE47_RS01995	COG0463	Glycosyl transferase, family 2
HUE47_RS02000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUE47_RS02005	COG1132	(ABC) transporter
HUE47_RS02020	COG0739	heme binding
HUE47_RS02035	COG1418	mRNA catabolic process
HUE47_RS02040	COG2205	protein histidine kinase activity
HUE47_RS02060	COG1678	Uncharacterized ACR, COG1678
HUE47_RS02065	COG0776	regulation of translation
HUE47_RS02070	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUE47_RS02075	COG0514	ATP-dependent DNA helicase (RecQ)
HUE47_RS02095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUE47_RS02100	COG0730	response to heat
HUE47_RS02120	COG4974	Belongs to the 'phage' integrase family
HUE47_RS02125	COG0124	histidyl-tRNA synthetase
HUE47_RS02130	COG0577	efflux transmembrane transporter activity
HUE47_RS02130	COG1136	(ABC) transporter
HUE47_RS02135	COG2890	protein-(glutamine-N5) methyltransferase activity
HUE47_RS02140	COG0456	acetyltransferase
HUE47_RS02145	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUE47_RS02145	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUE47_RS02150	COG1011	Hydrolase
HUE47_RS02155	COG1739	Uncharacterized protein family UPF0029
HUE47_RS02160	COG0824	Thioesterase
HUE47_RS02165	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HUE47_RS02170	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUE47_RS02175	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HUE47_RS02185	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HUE47_RS02195	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HUE47_RS02200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUE47_RS02230	COG0791	NLP P60 protein
HUE47_RS02230	COG1388	LysM domain
HUE47_RS02240	COG1515	deoxyribonuclease V activity
HUE47_RS02330	COG0714	Associated with various cellular activities
HUE47_RS02340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUE47_RS02345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUE47_RS02380	COG0784	Response regulator, receiver
HUE47_RS02380	COG2198	Histidine kinase
HUE47_RS02380	COG5002	protein histidine kinase activity
HUE47_RS02385	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HUE47_RS02400	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HUE47_RS02405	COG0085	RNA polymerase activity
HUE47_RS02410	COG0222	ribosome binding
HUE47_RS02415	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HUE47_RS02420	COG0081	regulation of translation
HUE47_RS02425	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HUE47_RS02445	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HUE47_RS02470	COG4974	Belongs to the 'phage' integrase family
HUE47_RS02475	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HUE47_RS02480	COG0492	ferredoxin-NADP+ reductase activity
HUE47_RS02485	COG1960	acyl-CoA dehydrogenase activity
HUE47_RS02520	COG4771	TonB-dependent receptor
HUE47_RS02525	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HUE47_RS02530	COG0321	lipoyl(octanoyl) transferase activity
HUE47_RS02545	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUE47_RS02560	COG4774	siderophore transport
HUE47_RS02570	COG1858	cytochrome C peroxidase
HUE47_RS02625	COG4263	nitrous-oxide reductase activity
HUE47_RS02635	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUE47_RS02645	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HUE47_RS02665	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HUE47_RS02675	COG2346	COG2346, Truncated hemoglobins
HUE47_RS02680	COG3186	Phenylalanine-4-hydroxylase
HUE47_RS02685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUE47_RS02710	COG1132	(ABC) transporter
HUE47_RS02735	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HUE47_RS02755	COG1160	GTP binding
HUE47_RS02765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUE47_RS02770	COG3938	Belongs to the proline racemase family
HUE47_RS02780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUE47_RS02795	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HUE47_RS02805	COG1704	LemA family
HUE47_RS02815	COG4942	peptidase
HUE47_RS02820	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUE47_RS02830	COG1215	transferase activity, transferring glycosyl groups
HUE47_RS02835	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUE47_RS02890	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HUE47_RS02895	COG0295	cytidine deaminase activity
HUE47_RS02910	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUE47_RS02915	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HUE47_RS02965	COG4974	Belongs to the 'phage' integrase family
HUE47_RS02980	COG4974	Belongs to the 'phage' integrase family
HUE47_RS03085	COG1363	Peptidase, m42
HUE47_RS03115	COG3335	DDE superfamily endonuclease
HUE47_RS03135	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HUE47_RS03140	COG1017	nitric oxide dioxygenase activity
HUE47_RS03140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUE47_RS03145	COG1959	2 iron, 2 sulfur cluster binding
HUE47_RS03160	COG1702	phosphate starvation-inducible protein PhoH
HUE47_RS03190	COG0513	Belongs to the DEAD box helicase family
HUE47_RS03230	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HUE47_RS03240	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HUE47_RS03245	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HUE47_RS03330	COG2801	Transposase and inactivated derivatives
HUE47_RS03335	COG2963	transposase activity
HUE47_RS03355	COG0514	ATP-dependent DNA helicase (RecQ)
HUE47_RS03360	COG0517	IMP dehydrogenase activity
HUE47_RS03360	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HUE47_RS03365	COG0805	protein transport
HUE47_RS03375	COG1137	ATPase activity
HUE47_RS03430	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HUE47_RS03445	COG0438	transferase activity, transferring glycosyl groups
HUE47_RS03470	COG0297	glycogen (starch) synthase activity
HUE47_RS03470	COG0438	transferase activity, transferring glycosyl groups
HUE47_RS03485	COG2089	acid synthase
HUE47_RS03490	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HUE47_RS03515	COG0438	transferase activity, transferring glycosyl groups
HUE47_RS03530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUE47_RS03535	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HUE47_RS03555	COG4464	protein tyrosine phosphatase activity
HUE47_RS03575	COG1086	Polysaccharide biosynthesis protein
HUE47_RS03580	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HUE47_RS03590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HUE47_RS03605	COG0367	asparagine synthase
HUE47_RS03625	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HUE47_RS03635	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUE47_RS03640	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HUE47_RS03650	COG0489	protein tyrosine kinase activity
HUE47_RS03650	COG3206	protein involved in exopolysaccharide biosynthesis
HUE47_RS03660	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HUE47_RS03670	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUE47_RS03675	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUE47_RS03685	COG2095	MarC family integral membrane protein
HUE47_RS03695	COG0010	Belongs to the arginase family
HUE47_RS03735	COG0358	DNA primase activity
HUE47_RS03740	COG4974	Belongs to the 'phage' integrase family
HUE47_RS03770	COG0148	phosphopyruvate hydratase activity
HUE47_RS03780	COG0203	ribosomal protein L17
HUE47_RS03785	COG0202	RNA polymerase activity
HUE47_RS03790	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HUE47_RS03795	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HUE47_RS03800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HUE47_RS03805	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HUE47_RS03810	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HUE47_RS03820	COG0200	Binds to the 23S rRNA
HUE47_RS03825	COG1841	ribosomal large subunit assembly
HUE47_RS03830	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HUE47_RS03840	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HUE47_RS03845	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HUE47_RS03850	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUE47_RS03855	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HUE47_RS03860	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HUE47_RS03865	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HUE47_RS03870	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HUE47_RS03875	COG0255	Belongs to the universal ribosomal protein uL29 family
HUE47_RS03880	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HUE47_RS03885	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HUE47_RS03890	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HUE47_RS03895	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HUE47_RS03900	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HUE47_RS03905	COG0089	rRNA binding
HUE47_RS03910	COG0088	Forms part of the polypeptide exit tunnel
HUE47_RS03915	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HUE47_RS03920	COG0051	transcription antitermination factor activity, RNA binding
HUE47_RS03925	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUE47_RS03930	COG0049	tRNA binding
HUE47_RS03935	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HUE47_RS03945	COG4206	TonB-dependent receptor
HUE47_RS03945	COG1629	transport
HUE47_RS03955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUE47_RS03965	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HUE47_RS03985	COG1011	Hydrolase
HUE47_RS04000	COG1136	(ABC) transporter
HUE47_RS04005	COG2003	Belongs to the UPF0758 family
HUE47_RS04030	COG0076	glutamate decarboxylase activity
HUE47_RS04035	COG3486	L-lysine 6-monooxygenase (NADPH) activity
HUE47_RS04065	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUE47_RS04075	COG3591	Belongs to the peptidase S1B family
HUE47_RS04120	COG2234	aminopeptidase activity
HUE47_RS04120	COG4935	Belongs to the peptidase S8 family
HUE47_RS04130	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HUE47_RS04135	COG1253	flavin adenine dinucleotide binding
HUE47_RS04140	COG0563	adenylate kinase activity
HUE47_RS04150	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HUE47_RS04155	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HUE47_RS04165	COG2949	membrane
HUE47_RS04170	COG1510	regulation of RNA biosynthetic process
HUE47_RS04210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUE47_RS04225	COG4953	penicillin-binding protein 1C
HUE47_RS04230	COG2373	Large extracellular alpha-helical protein
HUE47_RS04235	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUE47_RS04235	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUE47_RS04240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUE47_RS04340	COG3586	endonuclease activity
HUE47_RS04390	COG0076	glutamate decarboxylase activity
HUE47_RS04395	COG0277	FAD linked oxidase domain protein
HUE47_RS04395	COG0247	lactate metabolic process
HUE47_RS04400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUE47_RS04415	COG1522	sequence-specific DNA binding
HUE47_RS04425	COG3420	alginic acid biosynthetic process
HUE47_RS04435	COG0488	(ABC) transporter
HUE47_RS04490	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUE47_RS04505	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUE47_RS04535	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HUE47_RS04540	COG0459	protein refolding
HUE47_RS04615	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HUE47_RS04645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUE47_RS04660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUE47_RS04670	COG0842	Transport permease protein
HUE47_RS04675	COG1131	(ABC) transporter
HUE47_RS04695	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HUE47_RS04700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUE47_RS04715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUE47_RS04725	COG1028	Short-chain dehydrogenase reductase Sdr
HUE47_RS04765	COG0659	secondary active sulfate transmembrane transporter activity
HUE47_RS04770	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUE47_RS04775	COG3002	Belongs to the UPF0753 family
HUE47_RS04785	COG0586	Pfam SNARE associated Golgi protein
HUE47_RS04790	COG0288	reversible hydration of carbon dioxide
HUE47_RS04800	COG0659	secondary active sulfate transmembrane transporter activity
HUE47_RS04840	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HUE47_RS04845	COG1185	polyribonucleotide nucleotidyltransferase activity
HUE47_RS04850	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUE47_RS04935	COG1610	YqeY-like protein
HUE47_RS04940	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HUE47_RS04955	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUE47_RS04960	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HUE47_RS04965	COG0772	Belongs to the SEDS family
HUE47_RS04970	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HUE47_RS04975	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUE47_RS04980	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HUE47_RS04985	COG0768	penicillin binding
HUE47_RS04995	COG0275	rRNA processing
HUE47_RS05000	COG2001	Belongs to the MraZ family
HUE47_RS05010	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HUE47_RS05020	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HUE47_RS05040	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HUE47_RS05055	COG0358	DNA primase activity
HUE47_RS05075	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HUE47_RS05085	COG0646	methionine synthase
HUE47_RS05085	COG1410	methionine synthase
HUE47_RS05090	COG0460	homoserine dehydrogenase
HUE47_RS05090	COG0527	aspartate kinase activity
HUE47_RS05120	COG3335	DDE superfamily endonuclease
HUE47_RS05140	COG1215	transferase activity, transferring glycosyl groups
HUE47_RS05160	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HUE47_RS05170	COG1428	Deoxynucleoside kinase
HUE47_RS05175	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HUE47_RS05185	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HUE47_RS05195	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HUE47_RS05200	COG2086	electron transfer activity
HUE47_RS05205	COG0022	dehydrogenase e1 component
HUE47_RS05205	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUE47_RS05215	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HUE47_RS05220	COG2226	methyltransferase
HUE47_RS05245	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HUE47_RS05250	COG0577	efflux transmembrane transporter activity
HUE47_RS05250	COG1136	(ABC) transporter
HUE47_RS05255	COG0138	bifunctional purine biosynthesis protein purh
HUE47_RS05265	COG0450	alkyl hydroperoxide reductase
HUE47_RS05270	COG1077	Cell shape determining protein MreB Mrl
HUE47_RS05285	COG0768	penicillin binding
HUE47_RS05290	COG0772	Belongs to the SEDS family
HUE47_RS05330	COG3104	oligopeptide transport
HUE47_RS05340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUE47_RS05345	COG2333	competence protein COMEC
HUE47_RS05345	COG0658	competence protein
HUE47_RS05350	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUE47_RS05360	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HUE47_RS05365	COG0793	Belongs to the peptidase S41A family
HUE47_RS05375	COG3335	DDE superfamily endonuclease
HUE47_RS05400	COG1187	pseudouridine synthase activity
HUE47_RS05420	COG2081	HI0933 family
HUE47_RS05445	COG0460	homoserine dehydrogenase
HUE47_RS05445	COG0527	aspartate kinase activity
HUE47_RS05455	COG0501	Belongs to the peptidase M48B family
HUE47_RS05460	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HUE47_RS05480	COG3179	chitinase
HUE47_RS05490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUE47_RS05510	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HUE47_RS05560	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HUE47_RS05570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUE47_RS05575	COG1428	Deoxynucleoside kinase
HUE47_RS05580	COG0616	signal peptide processing
HUE47_RS05600	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HUE47_RS05605	COG0740	serine-type endopeptidase activity
HUE47_RS05610	COG0544	peptidyl-prolyl cis-trans isomerase activity
HUE47_RS05625	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HUE47_RS05635	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUE47_RS05645	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUE47_RS05665	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HUE47_RS05670	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HUE47_RS05685	COG0668	transmembrane transport
HUE47_RS05690	COG1214	PFAM Peptidase M22, glycoprotease
HUE47_RS05695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUE47_RS05715	COG2322	membrane
HUE47_RS05720	COG1999	signal sequence binding
HUE47_RS05740	COG1845	cytochrome c oxidase, subunit III
HUE47_RS05745	COG0109	protoheme IX farnesyltransferase activity
HUE47_RS05770	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HUE47_RS05780	COG0509	glycine decarboxylation via glycine cleavage system
HUE47_RS05790	COG0632	four-way junction helicase activity
HUE47_RS05800	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HUE47_RS05805	COG2255	four-way junction helicase activity
HUE47_RS05810	COG0531	amino acid
HUE47_RS05815	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HUE47_RS05820	COG0195	Participates in both transcription termination and antitermination
HUE47_RS05820	COG2251	uridine kinase activity
HUE47_RS05825	COG0779	Required for maturation of 30S ribosomal subunits
HUE47_RS05830	COG0589	response to stress
HUE47_RS05860	COG2095	MarC family integral membrane protein
HUE47_RS05875	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUE47_RS05875	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HUE47_RS05890	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HUE47_RS05900	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUE47_RS05905	COG0590	tRNA wobble adenosine to inosine editing
HUE47_RS05910	COG1278	Cold shock
HUE47_RS05930	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HUE47_RS05960	COG0228	four-way junction DNA binding
HUE47_RS05965	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HUE47_RS05970	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HUE47_RS05975	COG3185	4-Hydroxyphenylpyruvate dioxygenase
HUE47_RS05980	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HUE47_RS05990	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUE47_RS06000	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HUE47_RS06005	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HUE47_RS06015	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUE47_RS06020	COG0196	riboflavin kinase activity
HUE47_RS06040	COG0346	lactoylglutathione lyase activity
HUE47_RS06045	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HUE47_RS06055	COG1960	acyl-CoA dehydrogenase activity
HUE47_RS06090	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUE47_RS06095	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HUE47_RS06100	COG0193	aminoacyl-tRNA hydrolase activity
HUE47_RS06125	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HUE47_RS06130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUE47_RS06155	COG2315	Protein conserved in bacteria
HUE47_RS06165	COG0166	Belongs to the GPI family
HUE47_RS06170	COG3483	tryptophan 2,3-dioxygenase activity
HUE47_RS06180	COG0180	Tryptophanyl-tRNA synthetase
HUE47_RS06220	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HUE47_RS06240	COG2801	Transposase and inactivated derivatives
HUE47_RS06340	COG1459	type II secretion system
HUE47_RS06405	COG0542	response to heat
HUE47_RS06520	COG1028	Short-chain dehydrogenase reductase Sdr
HUE47_RS06535	COG3540	Alkaline phosphatase
HUE47_RS06540	COG2814	Major facilitator Superfamily
HUE47_RS06555	COG0567	Dehydrogenase, E1 component
HUE47_RS06560	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUE47_RS06565	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HUE47_RS06585	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUE47_RS06600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUE47_RS06605	COG2963	transposase activity
HUE47_RS06610	COG2801	Transposase and inactivated derivatives
HUE47_RS06620	COG2239	Acts as a magnesium transporter
HUE47_RS06625	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUE47_RS06640	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HUE47_RS06655	COG0756	dUTP diphosphatase activity
HUE47_RS06660	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HUE47_RS06695	COG1418	mRNA catabolic process
HUE47_RS06700	COG1024	Enoyl-CoA hydratase
HUE47_RS06705	COG5000	phosphorelay sensor kinase activity
HUE47_RS06710	COG1981	membrane
HUE47_RS06715	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HUE47_RS06725	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HUE47_RS06730	COG0181	hydroxymethylbilane synthase activity
HUE47_RS06740	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HUE47_RS06750	COG0408	coproporphyrinogen oxidase activity
HUE47_RS06760	COG0113	porphobilinogen synthase activity
HUE47_RS06770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUE47_RS06805	COG1914	H( )-stimulated, divalent metal cation uptake system
HUE47_RS06815	COG4771	TonB-dependent receptor
HUE47_RS06915	COG3209	COG3209 Rhs family protein
HUE47_RS06930	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HUE47_RS06935	COG0423	glycine-tRNA ligase activity
HUE47_RS06955	COG1876	peptidase activity
HUE47_RS06975	COG3621	Patatin-like phospholipase
HUE47_RS07020	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUE47_RS07025	COG1053	succinate dehydrogenase
HUE47_RS07045	COG0006	proline dipeptidase activity
HUE47_RS07055	COG2267	carboxylic ester hydrolase activity
HUE47_RS07070	COG0156	8-amino-7-oxononanoate synthase activity
HUE47_RS07075	COG1074	ATP-dependent DNA helicase activity
HUE47_RS07085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HUE47_RS07090	COG0322	excinuclease ABC activity
HUE47_RS07095	COG1752	Esterase of the alpha-beta hydrolase superfamily
HUE47_RS07100	COG0531	amino acid
HUE47_RS07105	COG0481	GTPase activity
HUE47_RS07110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HUE47_RS07125	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HUE47_RS07130	COG2363	Small membrane protein
HUE47_RS07140	COG1522	sequence-specific DNA binding
HUE47_RS07150	COG0793	Belongs to the peptidase S41A family
HUE47_RS07165	COG3852	Histidine kinase
HUE47_RS07170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUE47_RS07180	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HUE47_RS07200	COG0501	Belongs to the peptidase M48B family
HUE47_RS07205	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HUE47_RS07215	COG2022	thiamine diphosphate biosynthetic process
HUE47_RS07220	COG0352	thiamine-phosphate diphosphorylase activity
HUE47_RS07230	COG0352	thiamine-phosphate diphosphorylase activity
HUE47_RS07235	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HUE47_RS07245	COG0519	Catalyzes the synthesis of GMP from XMP
HUE47_RS07255	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HUE47_RS07260	COG1968	undecaprenyl-diphosphatase activity
HUE47_RS07270	COG2177	Part of the ABC transporter FtsEX involved in
HUE47_RS07280	COG0671	phosphoesterase, PA-phosphatase related
HUE47_RS07285	COG0495	leucyl-tRNA aminoacylation
HUE47_RS07305	COG2153	protein acetylation
HUE47_RS07310	COG0791	NLP P60 protein
HUE47_RS07310	COG1388	LysM domain
HUE47_RS07315	COG0126	phosphoglycerate kinase activity
HUE47_RS07350	COG0470	DNA polymerase III
HUE47_RS07370	COG0445	tRNA wobble uridine modification
HUE47_RS07375	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HUE47_RS07385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUE47_RS07400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUE47_RS07440	COG0557	exoribonuclease II activity
HUE47_RS07455	COG2860	membrane
HUE47_RS07525	COG0137	argininosuccinate synthase activity
HUE47_RS07530	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HUE47_RS07545	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HUE47_RS07555	COG0165	Argininosuccinate lyase
HUE47_RS07560	COG1522	sequence-specific DNA binding
HUE47_RS07565	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUE47_RS07615	COG0758	DNA mediated transformation
HUE47_RS07615	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUE47_RS07625	COG1607	acyl-coa hydrolase
HUE47_RS07635	COG0697	spore germination
HUE47_RS07655	COG0629	single-stranded DNA binding
HUE47_RS07660	COG0662	Cupin 2, conserved barrel domain protein
HUE47_RS07660	COG2207	Transcriptional regulator
HUE47_RS07670	COG1131	(ABC) transporter
HUE47_RS07680	COG1054	Belongs to the UPF0176 family
HUE47_RS07685	COG0826	peptidase U32
HUE47_RS07695	COG1774	PSP1 C-terminal conserved region
HUE47_RS07705	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HUE47_RS07710	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HUE47_RS07730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HUE47_RS07735	COG0745	RESPONSE REGULATOR receiver
HUE47_RS07780	COG3279	Response regulator of the LytR AlgR family
HUE47_RS07790	COG2205	protein histidine kinase activity
HUE47_RS07800	COG5002	protein histidine kinase activity
HUE47_RS07810	COG0784	Response regulator, receiver
HUE47_RS07820	COG1528	Iron-storage protein
HUE47_RS07825	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUE47_RS07825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUE47_RS07830	COG1619	proteins homologs of microcin C7 resistance protein MccF
HUE47_RS07835	COG0792	nuclease activity
HUE47_RS07845	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HUE47_RS07890	COG0750	zinc metalloprotease
HUE47_RS07900	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HUE47_RS07900	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HUE47_RS07910	COG1999	signal sequence binding
HUE47_RS07915	COG3590	peptidase
HUE47_RS07950	COG1215	transferase activity, transferring glycosyl groups
HUE47_RS07960	COG0151	Belongs to the GarS family
HUE47_RS07975	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HUE47_RS07995	COG1017	nitric oxide dioxygenase activity
HUE47_RS07995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUE47_RS08025	COG0356	it plays a direct role in the translocation of protons across the membrane
HUE47_RS08030	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUE47_RS08035	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HUE47_RS08040	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUE47_RS08045	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HUE47_RS08050	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HUE47_RS08055	COG0307	riboflavin synthase, alpha
HUE47_RS08060	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HUE47_RS08070	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HUE47_RS08075	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUE47_RS08080	COG0511	ligase activity, forming carbon-carbon bonds
HUE47_RS08085	COG0439	Biotin carboxylase
HUE47_RS08115	COG4206	TonB-dependent receptor
HUE47_RS08115	COG1629	transport
HUE47_RS08120	COG0745	RESPONSE REGULATOR receiver
HUE47_RS08125	COG5002	protein histidine kinase activity
HUE47_RS08155	COG2824	Alkylphosphonate utilization operon protein PhnA
HUE47_RS08165	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUE47_RS08190	COG0594	ribonuclease P activity
HUE47_RS08200	COG2217	Heavy metal translocating P-type atpase
HUE47_RS08210	COG0492	ferredoxin-NADP+ reductase activity
HUE47_RS08220	COG0489	protein tyrosine kinase activity
HUE47_RS08240	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HUE47_RS08315	COG2137	regulation of response to DNA damage stimulus
HUE47_RS08320	COG4771	TonB-dependent receptor
HUE47_RS08330	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HUE47_RS08345	COG0156	8-amino-7-oxononanoate synthase activity
HUE47_RS08350	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUE47_RS08380	COG0194	GDP metabolic process
HUE47_RS08390	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HUE47_RS08425	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HUE47_RS08460	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUE47_RS08465	COG1056	cytidyltransferase-related domain
HUE47_RS08465	COG1051	belongs to the nudix hydrolase family
HUE47_RS08470	COG1979	alcohol dehydrogenase
HUE47_RS08480	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HUE47_RS08490	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HUE47_RS08505	COG0719	Fe-S assembly protein
HUE47_RS08515	COG0396	ATPase activity
HUE47_RS08520	COG0655	NAD(P)H dehydrogenase (quinone) activity
HUE47_RS08525	COG0719	Fe-S assembly protein
HUE47_RS08530	COG0316	Belongs to the HesB IscA family
HUE47_RS08540	COG0501	Belongs to the peptidase M48B family
HUE47_RS08545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUE47_RS08570	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUE47_RS08600	COG1012	belongs to the aldehyde dehydrogenase family
HUE47_RS08605	COG0626	cystathionine gamma-synthase activity
HUE47_RS08615	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUE47_RS08630	COG1381	Involved in DNA repair and RecF pathway recombination
HUE47_RS08645	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HUE47_RS08655	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HUE47_RS08670	COG0328	RNA-DNA hybrid ribonuclease activity
HUE47_RS08675	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUE47_RS08680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUE47_RS08685	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUE47_RS08690	COG0571	ribonuclease III activity
HUE47_RS08700	COG0714	Associated with various cellular activities
HUE47_RS08720	COG2304	oxidoreductase activity
HUE47_RS08760	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUE47_RS08770	COG2166	iron-sulfur cluster assembly
HUE47_RS08775	COG2151	metal-sulfur cluster biosynthetic enzyme
HUE47_RS08790	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HUE47_RS08795	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUE47_RS08805	COG0469	pyruvate kinase activity
HUE47_RS08810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUE47_RS08815	COG2954	triphosphatase activity
HUE47_RS08820	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HUE47_RS08835	COG0708	Exodeoxyribonuclease III
HUE47_RS08840	COG1360	Flagellar Motor Protein
HUE47_RS08845	COG0667	Aldo Keto reductase
HUE47_RS08855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUE47_RS08865	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HUE47_RS08880	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HUE47_RS08885	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HUE47_RS08890	COG0297	glycogen (starch) synthase activity
HUE47_RS08900	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUE47_RS08905	COG0823	Involved in the tonB-independent uptake of proteins
HUE47_RS08905	COG1506	peptidase
HUE47_RS08915	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HUE47_RS08930	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUE47_RS08935	COG0463	Glycosyl transferase, family 2
HUE47_RS08965	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HUE47_RS08975	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HUE47_RS08990	COG3335	DDE superfamily endonuclease
HUE47_RS09015	COG0252	asparaginase activity
HUE47_RS09025	COG0084	hydrolase, TatD family'
HUE47_RS09040	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HUE47_RS09045	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HUE47_RS09050	COG0720	synthase
HUE47_RS09080	COG0629	single-stranded DNA binding
HUE47_RS09085	COG1194	a g-specific adenine glycosylase
HUE47_RS09090	COG0776	regulation of translation
HUE47_RS09095	COG1530	ribonuclease E activity
HUE47_RS09100	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUE47_RS09105	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUE47_RS09110	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUE47_RS09115	COG0649	NAD binding
HUE47_RS09120	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HUE47_RS09130	COG1034	ATP synthesis coupled electron transport
HUE47_RS09135	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUE47_RS09140	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUE47_RS09145	COG0839	Belongs to the complex I subunit 6 family
HUE47_RS09150	COG0713	ATP synthesis coupled electron transport
HUE47_RS09155	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUE47_RS09160	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUE47_RS09165	COG1007	ATP synthesis coupled electron transport
HUE47_RS09180	COG0437	4 iron, 4 sulfur cluster binding
HUE47_RS09205	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HUE47_RS09210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUE47_RS09250	COG0475	glutathione-regulated potassium exporter activity
HUE47_RS09265	COG0017	Asparaginyl-tRNA synthetase
HUE47_RS09280	COG2217	Heavy metal translocating P-type atpase
HUE47_RS09300	COG0427	acetyl-CoA hydrolase
HUE47_RS09315	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUE47_RS09325	COG2967	ApaG domain
HUE47_RS09330	COG1012	belongs to the aldehyde dehydrogenase family
HUE47_RS09340	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HUE47_RS09360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUE47_RS09370	COG3541	Predicted nucleotidyltransferase
HUE47_RS09375	COG1690	Belongs to the RtcB family
HUE47_RS09390	COG0436	Aminotransferase
HUE47_RS09395	COG3239	Fatty acid desaturase
HUE47_RS09400	COG0357	Ribosomal RNA small subunit methyltransferase G
HUE47_RS09415	COG0826	peptidase U32
HUE47_RS09440	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HUE47_RS09455	COG0840	transmembrane signaling receptor activity
HUE47_RS09460	COG0528	UMP kinase activity
HUE47_RS09465	COG0233	cytoplasmic translational termination
HUE47_RS09520	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HUE47_RS09525	COG0052	Belongs to the universal ribosomal protein uS2 family
HUE47_RS09530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HUE47_RS09540	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUE47_RS09540	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUE47_RS09610	COG4717	serine-type aminopeptidase activity
HUE47_RS09615	COG3275	phosphorelay sensor kinase activity
HUE47_RS09620	COG3279	Response regulator of the LytR AlgR family
HUE47_RS09630	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HUE47_RS09630	COG1519	Transferase
HUE47_RS09640	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUE47_RS09645	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HUE47_RS09665	COG2989	Protein conserved in bacteria
HUE47_RS09675	COG3340	Belongs to the peptidase S51 family
HUE47_RS09700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUE47_RS09705	COG0671	phosphoesterase, PA-phosphatase related
HUE47_RS09710	COG4122	O-methyltransferase activity
HUE47_RS09715	COG2022	thiamine diphosphate biosynthetic process
HUE47_RS09720	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HUE47_RS09735	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HUE47_RS09740	COG1162	GTPase activity
HUE47_RS09745	COG1490	D-aminoacyl-tRNA deacylase activity
HUE47_RS09755	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUE47_RS09760	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HUE47_RS09780	COG3844	kynureninase activity
HUE47_RS09790	COG0010	Belongs to the arginase family
HUE47_RS09800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUE47_RS09810	COG0433	COG0433 Predicted ATPase
HUE47_RS09825	COG0848	biopolymer transport protein
HUE47_RS09850	COG0602	queuosine metabolic process
HUE47_RS09870	COG0840	transmembrane signaling receptor activity
HUE47_RS09875	COG3876	Protein conserved in bacteria
HUE47_RS09970	COG2801	Transposase and inactivated derivatives
HUE47_RS09985	COG0012	GTP binding
HUE47_RS10010	COG4804	nuclease activity
HUE47_RS10030	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HUE47_RS10035	COG0322	excinuclease ABC activity
HUE47_RS10040	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HUE47_RS10060	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUE47_RS10065	COG4804	nuclease activity
HUE47_RS10070	COG0673	inositol 2-dehydrogenase activity
HUE47_RS10075	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HUE47_RS10080	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HUE47_RS10085	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUE47_RS10090	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HUE47_RS10095	COG1404	Belongs to the peptidase S8 family
HUE47_RS10105	COG0531	amino acid
HUE47_RS10110	COG1690	Belongs to the RtcB family
HUE47_RS10120	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUE47_RS10140	COG0494	nUDIX hydrolase
HUE47_RS10145	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUE47_RS10145	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUE47_RS10150	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUE47_RS10165	COG0572	uridine kinase
HUE47_RS10175	COG0149	triose-phosphate isomerase activity
HUE47_RS10180	COG3118	belongs to the thioredoxin family
HUE47_RS10195	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HUE47_RS10210	COG1132	(ABC) transporter
HUE47_RS10215	COG0101	tRNA pseudouridine synthase activity
HUE47_RS10225	COG0424	maF-like protein
HUE47_RS10235	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HUE47_RS10250	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUE47_RS10250	COG1333	cytochrome c biogenesis protein
HUE47_RS10255	COG0386	Belongs to the glutathione peroxidase family
HUE47_RS10260	COG0386	Belongs to the glutathione peroxidase family
HUE47_RS10275	COG1028	Short-chain dehydrogenase reductase Sdr
HUE47_RS10280	COG0702	epimerase
HUE47_RS10310	COG0415	Belongs to the DNA photolyase family
HUE47_RS10335	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUE47_RS10350	COG0442	prolyl-tRNA aminoacylation
HUE47_RS10370	COG0268	Binds directly to 16S ribosomal RNA
HUE47_RS10375	COG1217	gtp-binding protein TYPA
HUE47_RS10395	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HUE47_RS10400	COG0105	UTP biosynthetic process
HUE47_RS10420	COG2264	protein methyltransferase activity
HUE47_RS10425	COG1247	-acetyltransferase
HUE47_RS10435	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HUE47_RS10445	COG2996	Protein conserved in bacteria
HUE47_RS10460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUE47_RS10490	COG1858	cytochrome C peroxidase
HUE47_RS10500	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUE47_RS10525	COG2962	Rard protein
HUE47_RS10540	COG0443	Heat shock 70 kDa protein
HUE47_RS10560	COG2247	cell wall binding repeat
HUE47_RS10560	COG0860	N-Acetylmuramoyl-L-alanine amidase
HUE47_RS10570	COG2181	nitrate reductase activity
HUE47_RS10570	COG0247	lactate metabolic process
HUE47_RS10575	COG2181	nitrate reductase activity
HUE47_RS10575	COG0247	lactate metabolic process
HUE47_RS10585	COG1472	Belongs to the glycosyl hydrolase 3 family
HUE47_RS10590	COG0438	transferase activity, transferring glycosyl groups
HUE47_RS10595	COG0737	Belongs to the 5'-nucleotidase family
HUE47_RS10600	COG0737	Belongs to the 5'-nucleotidase family
HUE47_RS10610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUE47_RS10635	COG0497	DNA recombination
HUE47_RS10640	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HUE47_RS10695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUE47_RS10715	COG0583	DNA-binding transcription factor activity
HUE47_RS10770	COG2378	regulation of single-species biofilm formation
HUE47_RS10800	COG0116	Belongs to the methyltransferase superfamily
HUE47_RS10805	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUE47_RS10815	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HUE47_RS10835	COG0861	Integral membrane protein TerC family
HUE47_RS10840	COG2234	aminopeptidase activity
HUE47_RS10845	COG0564	pseudouridine synthase activity
HUE47_RS10855	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUE47_RS10860	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HUE47_RS10875	COG1136	(ABC) transporter
HUE47_RS10875	COG0577	efflux transmembrane transporter activity
HUE47_RS10880	COG1136	(ABC) transporter
HUE47_RS10885	COG1733	regulation of RNA biosynthetic process
HUE47_RS10900	COG0513	Belongs to the DEAD box helicase family
HUE47_RS10910	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HUE47_RS10920	COG0367	asparagine synthase
HUE47_RS10925	COG0187	DNA topoisomerase II activity
HUE47_RS10935	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUE47_RS10940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUE47_RS10955	COG2814	Major facilitator Superfamily
HUE47_RS10975	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HUE47_RS10990	COG1228	amidohydrolase
HUE47_RS10995	COG0598	Magnesium transport protein CorA
HUE47_RS11010	COG1393	Belongs to the ArsC family
HUE47_RS11015	COG1266	CAAX protease self-immunity
HUE47_RS11030	COG0010	Belongs to the arginase family
HUE47_RS11035	COG0513	Belongs to the DEAD box helicase family
HUE47_RS11060	COG2321	neutral zinc metallopeptidase
HUE47_RS11070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUE47_RS11085	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HUE47_RS11095	COG0205	6-phosphofructokinase activity
HUE47_RS11110	COG1803	Methylglyoxal synthase
HUE47_RS11125	COG1136	(ABC) transporter
HUE47_RS11155	COG0628	permease
HUE47_RS11180	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HUE47_RS11220	COG2217	Heavy metal translocating P-type atpase
HUE47_RS11230	COG3278	Belongs to the heme-copper respiratory oxidase family
HUE47_RS11240	COG2010	Cytochrome c
HUE47_RS11245	COG0348	domain, Protein
HUE47_RS11265	COG1960	acyl-CoA dehydrogenase activity
HUE47_RS11270	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HUE47_RS11285	COG0606	chelatase, subunit chli
HUE47_RS11290	COG0804	urea catabolic process
HUE47_RS11295	COG1228	amidohydrolase
HUE47_RS11300	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HUE47_RS11305	COG3047	cAMP biosynthetic process
HUE47_RS11305	COG2885	chlorophyll binding
HUE47_RS11315	COG0284	orotidine-5'-phosphate decarboxylase activity
HUE47_RS11320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUE47_RS11375	COG0183	Belongs to the thiolase family
HUE47_RS11380	COG0791	NLP P60 protein
HUE47_RS11385	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HUE47_RS11405	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HUE47_RS11530	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUE47_RS11535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUE47_RS11565	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUE47_RS11570	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HUE47_RS11575	COG1301	dicarboxylic acid transport
HUE47_RS11580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUE47_RS11615	COG0693	protein deglycase activity
HUE47_RS11620	COG0346	lactoylglutathione lyase activity
HUE47_RS11630	COG0022	dehydrogenase e1 component
HUE47_RS11640	COG2234	aminopeptidase activity
HUE47_RS11645	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUE47_RS11675	COG3118	belongs to the thioredoxin family
HUE47_RS11695	COG1960	acyl-CoA dehydrogenase activity
HUE47_RS11705	COG0183	Belongs to the thiolase family
HUE47_RS11710	COG1024	Enoyl-CoA hydratase
HUE47_RS11710	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUE47_RS11715	COG1846	Transcriptional regulator
HUE47_RS11730	COG0482	sulfurtransferase activity
HUE47_RS11735	COG1404	Belongs to the peptidase S8 family
HUE47_RS11745	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUE47_RS11750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUE47_RS11765	COG1522	sequence-specific DNA binding
HUE47_RS11790	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUE47_RS11790	COG1703	isobutyryl-CoA mutase activity
HUE47_RS11790	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUE47_RS11800	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUE47_RS11800	COG0519	Catalyzes the synthesis of GMP from XMP
HUE47_RS11810	COG1388	LysM domain
HUE47_RS11810	COG3942	CHAP domain
HUE47_RS11820	COG3530	Putative quorum-sensing-regulated virulence factor
HUE47_RS11825	COG0504	CTP synthase activity
HUE47_RS11830	COG0706	membrane insertase activity
HUE47_RS11855	COG0754	glutathionylspermidine amidase activity
HUE47_RS11860	COG1216	Glycosyl transferase, family 2
HUE47_RS11885	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HUE47_RS11890	COG0167	dihydroorotate dehydrogenase activity
HUE47_RS11935	COG3275	phosphorelay sensor kinase activity
HUE47_RS11950	COG3279	Response regulator of the LytR AlgR family
HUE47_RS11965	COG0668	transmembrane transport
HUE47_RS11995	COG0488	(ABC) transporter
HUE47_RS12005	COG2342	PFAM TM1410 hypothetical-related protein
HUE47_RS12010	COG1309	transcriptional regulator
HUE47_RS12020	COG1764	response to oxidative stress
HUE47_RS12035	COG0753	catalase activity
HUE47_RS12040	COG0753	catalase activity
HUE47_RS12045	COG0450	alkyl hydroperoxide reductase
HUE47_RS12050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUE47_RS12075	COG0640	Transcriptional regulator
HUE47_RS12080	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HUE47_RS12090	COG1674	ftsk spoiiie
HUE47_RS12105	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUE47_RS12105	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUE47_RS12120	COG0671	phosphoesterase, PA-phosphatase related
HUE47_RS12205	COG1797	cobyrinic acid a,c-diamide synthase activity
HUE47_RS12215	COG1492	cobalamin metabolic process
HUE47_RS12220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUE47_RS12235	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HUE47_RS12245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUE47_RS12245	COG1648	precorrin-2 dehydrogenase activity
HUE47_RS12250	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
HUE47_RS12265	COG0778	Nitroreductase
HUE47_RS12285	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HUE47_RS12300	COG2096	Adenosyltransferase
HUE47_RS12325	COG0848	biopolymer transport protein
HUE47_RS12335	COG0285	dihydrofolate synthase activity
HUE47_RS12380	COG0248	Ppx GppA phosphatase
HUE47_RS12390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUE47_RS12410	COG1858	cytochrome C peroxidase
HUE47_RS12415	COG1028	Short-chain dehydrogenase reductase Sdr
HUE47_RS12425	COG2195	Cleaves the N-terminal amino acid of tripeptides
HUE47_RS12445	COG1575	Belongs to the MenA family. Type 1 subfamily
HUE47_RS12495	COG3335	DDE superfamily endonuclease
HUE47_RS12500	COG3012	SEC-C Motif Domain Protein
HUE47_RS12515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUE47_RS12515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUE47_RS12520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUE47_RS12520	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUE47_RS12535	COG0517	IMP dehydrogenase activity
HUE47_RS12535	COG0516	GMP reductase activity
HUE47_RS12555	COG2963	transposase activity
HUE47_RS12575	COG0009	L-threonylcarbamoyladenylate synthase
HUE47_RS12580	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HUE47_RS12600	COG1607	acyl-coa hydrolase
HUE47_RS12610	COG0799	negative regulation of ribosome biogenesis
HUE47_RS12615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUE47_RS12625	COG4589	Belongs to the CDS family
HUE47_RS12630	COG0688	phosphatidylethanolamine metabolic process
HUE47_RS12685	COG0746	molybdenum cofactor guanylyltransferase activity
HUE47_RS12705	COG0315	cyclic pyranopterin monophosphate synthase activity
HUE47_RS12705	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUE47_RS12710	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HUE47_RS12730	COG0243	molybdopterin cofactor binding
HUE47_RS12735	COG0437	4 iron, 4 sulfur cluster binding
HUE47_RS12770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUE47_RS12800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUE47_RS12805	COG2176	DNA-directed DNA polymerase activity
HUE47_RS12825	COG3158	transport of potassium into the cell
HUE47_RS12830	COG3781	membrane
HUE47_RS12860	COG0488	(ABC) transporter
HUE47_RS12870	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HUE47_RS12930	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HUE47_RS12945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUE47_RS12950	COG1595	DNA-templated transcription, initiation
HUE47_RS12990	COG2195	Cleaves the N-terminal amino acid of tripeptides
HUE47_RS12995	COG0022	dehydrogenase e1 component
HUE47_RS13010	COG0813	purine-nucleoside phosphorylase activity
HUE47_RS13040	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HUE47_RS13050	COG1696	Membrane protein involved in D-alanine export
HUE47_RS13060	COG1705	Flagellar rod assembly protein muramidase FlgJ
HUE47_RS13065	COG1193	negative regulation of DNA recombination
HUE47_RS13070	COG3011	Protein conserved in bacteria
HUE47_RS13080	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HUE47_RS13100	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HUE47_RS13115	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HUE47_RS13155	COG4585	Histidine kinase
HUE47_RS13175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUE47_RS13190	COG2010	Cytochrome c
HUE47_RS13195	COG3256	nitric oxide reductase
HUE47_RS13210	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUE47_RS13210	COG0515	serine threonine protein kinase
HUE47_RS13215	COG1999	signal sequence binding
HUE47_RS13220	COG0714	Associated with various cellular activities
HUE47_RS13230	COG1845	cytochrome c oxidase, subunit III
HUE47_RS13245	COG0436	Aminotransferase
HUE47_RS13250	COG0302	gtp cyclohydrolase
HUE47_RS13255	COG0215	cysteine-tRNA ligase activity
HUE47_RS13260	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HUE47_RS13270	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUE47_RS13280	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HUE47_RS13285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUE47_RS13295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUE47_RS13360	COG1012	belongs to the aldehyde dehydrogenase family
HUE47_RS13365	COG0564	pseudouridine synthase activity
HUE47_RS13370	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HUE47_RS13375	COG1970	mechanosensitive ion channel activity
HUE47_RS13380	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUE47_RS13385	COG1435	thymidine kinase activity
HUE47_RS13395	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HUE47_RS13405	COG3335	DDE superfamily endonuclease
HUE47_RS13420	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUE47_RS13430	COG0359	binds to the 23S rRNA
HUE47_RS13435	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUE47_RS13440	COG0360	Binds together with S18 to 16S ribosomal RNA
HUE47_RS13445	COG3279	Response regulator of the LytR AlgR family
HUE47_RS13450	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HUE47_RS13500	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HUE47_RS13505	COG3022	response to hydroperoxide
HUE47_RS13565	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HUE47_RS13565	COG0617	tRNA 3'-terminal CCA addition
HUE47_RS13565	COG0517	IMP dehydrogenase activity
HUE47_RS13570	COG1612	heme a metabolic process
HUE47_RS13575	COG2884	Cell division ATP-binding protein ftsE
HUE47_RS13585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUE47_RS13595	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HUE47_RS13605	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUE47_RS13610	COG0823	Involved in the tonB-independent uptake of proteins
HUE47_RS13610	COG1506	peptidase
HUE47_RS13615	COG1522	sequence-specific DNA binding
HUE47_RS13625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUE47_RS13670	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUE47_RS13690	COG1187	pseudouridine synthase activity
HUE47_RS13705	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HUE47_RS13710	COG1663	tetraacyldisaccharide 4'-kinase activity
HUE47_RS13730	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HUE47_RS13755	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUE47_RS13760	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HUE47_RS13760	COG0512	Glutamine amidotransferase of anthranilate synthase
HUE47_RS13765	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HUE47_RS13770	COG0134	indole-3-glycerol-phosphate synthase activity
HUE47_RS13775	COG0135	phosphoribosylanthranilate isomerase activity
HUE47_RS13780	COG0133	tryptophan synthase activity
HUE47_RS13785	COG0159	tryptophan synthase activity
HUE47_RS13815	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUE47_RS13830	COG1770	oligopeptidase
HUE47_RS13835	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HUE47_RS13845	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HUE47_RS13845	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HUE47_RS13855	COG1760	l-serine dehydratase
HUE47_RS13860	COG1368	sulfuric ester hydrolase activity
HUE47_RS13870	COG0045	succinate-CoA ligase (ADP-forming) activity
HUE47_RS13875	COG0019	diaminopimelate decarboxylase activity
HUE47_RS13885	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HUE47_RS13905	COG1611	Belongs to the LOG family
HUE47_RS13915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUE47_RS13925	COG2356	endonuclease I
HUE47_RS13930	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUE47_RS13930	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HUE47_RS13935	COG1309	transcriptional regulator
HUE47_RS13955	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HUE47_RS13960	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUE47_RS13965	COG0300	oxidoreductase activity
HUE47_RS13970	COG4948	Mandelate Racemase Muconate Lactonizing
HUE47_RS13985	COG0564	pseudouridine synthase activity
HUE47_RS13990	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HUE47_RS14010	COG0494	nUDIX hydrolase
HUE47_RS14035	COG0778	Nitroreductase
HUE47_RS14040	COG2353	YceI-like domain
HUE47_RS14045	COG2986	histidine ammonia-lyase
HUE47_RS14050	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HUE47_RS14055	COG0584	glycerophosphoryl diester phosphodiesterase
HUE47_RS14060	COG1104	cysteine desulfurase activity
HUE47_RS14070	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUE47_RS14075	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUE47_RS14095	COG0783	Belongs to the Dps family
HUE47_RS14105	COG0525	valine-tRNA ligase activity
HUE47_RS14115	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HUE47_RS14130	COG0116	Belongs to the methyltransferase superfamily
HUE47_RS14130	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HUE47_RS14135	COG0217	transcriptional regulatory protein
HUE47_RS14140	COG2963	transposase activity