locus-tag	class	description
HUE30_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HUE30_RS00015	COG0824	Thioesterase
HUE30_RS00020	COG1739	Uncharacterized protein family UPF0029
HUE30_RS00025	COG1011	Hydrolase
HUE30_RS00030	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUE30_RS00030	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUE30_RS00035	COG0456	acetyltransferase
HUE30_RS00040	COG2890	protein-(glutamine-N5) methyltransferase activity
HUE30_RS00045	COG0577	efflux transmembrane transporter activity
HUE30_RS00045	COG1136	(ABC) transporter
HUE30_RS00050	COG0124	histidyl-tRNA synthetase
HUE30_RS00055	COG4974	Belongs to the 'phage' integrase family
HUE30_RS00075	COG0730	response to heat
HUE30_RS00080	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUE30_RS00100	COG0514	ATP-dependent DNA helicase (RecQ)
HUE30_RS00105	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUE30_RS00110	COG0776	regulation of translation
HUE30_RS00115	COG1678	Uncharacterized ACR, COG1678
HUE30_RS00135	COG2205	protein histidine kinase activity
HUE30_RS00150	COG1418	mRNA catabolic process
HUE30_RS00165	COG0739	heme binding
HUE30_RS00180	COG1132	(ABC) transporter
HUE30_RS00185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUE30_RS00190	COG0463	Glycosyl transferase, family 2
HUE30_RS00200	COG0254	rRNA binding
HUE30_RS00210	COG1027	Aspartate ammonia-lyase
HUE30_RS00215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUE30_RS00255	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HUE30_RS00260	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUE30_RS00265	COG0038	chloride channel
HUE30_RS00270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUE30_RS00280	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUE30_RS00305	COG1607	acyl-coa hydrolase
HUE30_RS00320	COG1322	Protein conserved in bacteria
HUE30_RS00335	COG1187	pseudouridine synthase activity
HUE30_RS00345	COG1120	ATPase activity
HUE30_RS00350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUE30_RS00365	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
HUE30_RS00375	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HUE30_RS00380	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HUE30_RS00395	COG4206	TonB-dependent receptor
HUE30_RS00415	COG1881	PFAM PEBP family protein
HUE30_RS00450	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
HUE30_RS00455	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HUE30_RS00465	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HUE30_RS00470	COG1482	cell wall glycoprotein biosynthetic process
HUE30_RS00560	COG2963	transposase activity
HUE30_RS00570	COG2801	Transposase and inactivated derivatives
HUE30_RS00575	COG3177	Filamentation induced by cAMP protein fic
HUE30_RS00625	COG4974	Belongs to the 'phage' integrase family
HUE30_RS00650	COG0018	arginyl-trna synthetase
HUE30_RS00660	COG0556	nucleotide-excision repair
HUE30_RS00685	COG3015	lipoprotein NlpE involved in copper resistance
HUE30_RS00715	COG0572	uridine kinase
HUE30_RS00725	COG0335	large ribosomal subunit rRNA binding
HUE30_RS00745	COG0300	oxidoreductase activity
HUE30_RS00750	COG0336	Belongs to the RNA methyltransferase TrmD family
HUE30_RS00760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUE30_RS00770	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUE30_RS00820	COG0583	DNA-binding transcription factor activity
HUE30_RS00860	COG1215	transferase activity, transferring glycosyl groups
HUE30_RS00865	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HUE30_RS00875	COG3118	belongs to the thioredoxin family
HUE30_RS00880	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUE30_RS00890	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HUE30_RS00895	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HUE30_RS00920	COG0681	Belongs to the peptidase S26 family
HUE30_RS00925	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HUE30_RS00935	COG1475	DNA binding
HUE30_RS00940	COG1192	Involved in chromosome partitioning
HUE30_RS00945	COG0436	Aminotransferase
HUE30_RS00950	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
HUE30_RS01015	COG0653	protein targeting
HUE30_RS01040	COG0612	Peptidase, M16
HUE30_RS01045	COG1136	(ABC) transporter
HUE30_RS01055	COG3118	belongs to the thioredoxin family
HUE30_RS01070	COG0488	(ABC) transporter
HUE30_RS01085	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUE30_RS01095	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUE30_RS01105	COG1546	Belongs to the CinA family
HUE30_RS01105	COG1058	Belongs to the CinA family
HUE30_RS01110	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUE30_RS01115	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUE30_RS01125	COG0552	protein localization to endoplasmic reticulum
HUE30_RS01130	COG0492	ferredoxin-NADP+ reductase activity
HUE30_RS01210	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HUE30_RS01215	COG0484	heat shock protein binding
HUE30_RS01220	COG4152	abc transporter atp-binding protein
HUE30_RS01225	COG1668	transmembrane transport
HUE30_RS01230	COG2204	response regulator
HUE30_RS01245	COG0405	Gamma-glutamyltransferase
HUE30_RS01255	COG0488	(ABC) transporter
HUE30_RS01270	COG2304	oxidoreductase activity
HUE30_RS01290	COG1703	isobutyryl-CoA mutase activity
HUE30_RS01310	COG0277	FAD linked oxidase domain protein
HUE30_RS01335	COG2205	protein histidine kinase activity
HUE30_RS01335	COG0784	Response regulator, receiver
HUE30_RS01355	COG1278	Cold shock
HUE30_RS01360	COG0326	Molecular chaperone. Has ATPase activity
HUE30_RS01370	COG2885	chlorophyll binding
HUE30_RS01380	COG4977	sequence-specific DNA binding
HUE30_RS01385	COG3842	ATPase activity
HUE30_RS01395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUE30_RS01415	COG0463	Glycosyl transferase, family 2
HUE30_RS01435	COG2171	N-acyltransferase activity
HUE30_RS01440	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HUE30_RS01445	COG0579	oxidoreductase
HUE30_RS01450	COG0242	peptide deformylase activity
HUE30_RS01460	COG3956	TIGRFAM MazG family protein
HUE30_RS01470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUE30_RS01485	COG0037	tRNA processing
HUE30_RS01495	COG1252	NADH dehydrogenase
HUE30_RS01510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUE30_RS01520	COG0306	phosphate transporter
HUE30_RS01550	COG1234	tRNA 3'-trailer cleavage
HUE30_RS01560	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HUE30_RS01580	COG4771	TonB-dependent receptor
HUE30_RS01610	COG0740	serine-type endopeptidase activity
HUE30_RS01715	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HUE30_RS01720	COG3392	D12 class N6 adenine-specific DNA methyltransferase
HUE30_RS01725	COG1505	serine-type exopeptidase activity
HUE30_RS01730	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HUE30_RS01735	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HUE30_RS01750	COG0686	Belongs to the AlaDH PNT family
HUE30_RS01755	COG0802	atpase or kinase
HUE30_RS01760	COG2204	response regulator
HUE30_RS01765	COG3590	peptidase
HUE30_RS01770	COG1078	dGTPase activity
HUE30_RS01775	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUE30_RS01780	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HUE30_RS01780	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HUE30_RS01785	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUE30_RS01790	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HUE30_RS01795	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUE30_RS01800	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HUE30_RS01805	COG1022	Amp-dependent synthetase and ligase
HUE30_RS01820	COG2270	Major facilitator Superfamily
HUE30_RS01825	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HUE30_RS01835	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HUE30_RS01840	COG2211	Major facilitator Superfamily
HUE30_RS01850	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HUE30_RS01855	COG0540	Belongs to the ATCase OTCase family
HUE30_RS01880	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HUE30_RS01890	COG1234	tRNA 3'-trailer cleavage
HUE30_RS01895	COG0259	pyridoxamine-phosphate oxidase activity
HUE30_RS01910	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HUE30_RS01920	COG0542	response to heat
HUE30_RS01925	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUE30_RS01930	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUE30_RS01935	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUE30_RS01950	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HUE30_RS01955	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HUE30_RS01965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUE30_RS01970	COG0531	amino acid
HUE30_RS01980	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUE30_RS02010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUE30_RS02030	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HUE30_RS02045	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HUE30_RS02055	COG2323	membrane
HUE30_RS02060	COG4067	protein conserved in archaea
HUE30_RS02060	COG0189	ligase activity
HUE30_RS02065	COG0542	response to heat
HUE30_RS02070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUE30_RS02120	COG2801	Transposase and inactivated derivatives
HUE30_RS02130	COG2963	transposase activity
HUE30_RS02155	COG1862	Preprotein translocase
HUE30_RS02165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUE30_RS02175	COG1132	(ABC) transporter
HUE30_RS02185	COG0156	8-amino-7-oxononanoate synthase activity
HUE30_RS02190	COG3958	Transketolase
HUE30_RS02200	COG0343	queuine tRNA-ribosyltransferase activity
HUE30_RS02215	COG0825	malonyl-CoA metabolic process
HUE30_RS02220	COG0305	Participates in initiation and elongation during chromosome replication
HUE30_RS02230	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
HUE30_RS02235	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HUE30_RS02240	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HUE30_RS02245	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HUE30_RS02250	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HUE30_RS02360	COG3335	DDE superfamily endonuclease
HUE30_RS02380	COG0217	transcriptional regulatory protein
HUE30_RS02385	COG0116	Belongs to the methyltransferase superfamily
HUE30_RS02385	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HUE30_RS02400	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HUE30_RS02410	COG0525	valine-tRNA ligase activity
HUE30_RS02420	COG0783	Belongs to the Dps family
HUE30_RS02440	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUE30_RS02445	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUE30_RS02455	COG1104	cysteine desulfurase activity
HUE30_RS02465	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HUE30_RS02470	COG2986	histidine ammonia-lyase
HUE30_RS02475	COG2353	YceI-like domain
HUE30_RS02480	COG0778	Nitroreductase
HUE30_RS02500	COG3335	DDE superfamily endonuclease
HUE30_RS02515	COG0494	nUDIX hydrolase
HUE30_RS02525	COG2801	Transposase and inactivated derivatives
HUE30_RS02530	COG2963	transposase activity
HUE30_RS02540	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HUE30_RS02545	COG0564	pseudouridine synthase activity
HUE30_RS02560	COG4948	Mandelate Racemase Muconate Lactonizing
HUE30_RS02565	COG0300	oxidoreductase activity
HUE30_RS02570	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUE30_RS02575	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HUE30_RS02595	COG1309	transcriptional regulator
HUE30_RS02600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUE30_RS02600	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HUE30_RS02605	COG2356	endonuclease I
HUE30_RS02610	COG4733	cellulase activity
HUE30_RS02610	COG5297	Belongs to the glycosyl hydrolase family 6
HUE30_RS02615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUE30_RS02625	COG1611	Belongs to the LOG family
HUE30_RS02645	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HUE30_RS02655	COG0019	diaminopimelate decarboxylase activity
HUE30_RS02660	COG0045	succinate-CoA ligase (ADP-forming) activity
HUE30_RS02670	COG1368	sulfuric ester hydrolase activity
HUE30_RS02675	COG1760	l-serine dehydratase
HUE30_RS02685	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HUE30_RS02685	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HUE30_RS02690	COG2801	Transposase and inactivated derivatives
HUE30_RS02700	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HUE30_RS02705	COG1770	oligopeptidase
HUE30_RS02720	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUE30_RS02750	COG3392	D12 class N6 adenine-specific DNA methyltransferase
HUE30_RS03020	COG0159	tryptophan synthase activity
HUE30_RS03025	COG0133	tryptophan synthase activity
HUE30_RS03030	COG0135	phosphoribosylanthranilate isomerase activity
HUE30_RS03035	COG0134	indole-3-glycerol-phosphate synthase activity
HUE30_RS03040	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HUE30_RS03045	COG0512	Glutamine amidotransferase of anthranilate synthase
HUE30_RS03050	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUE30_RS03070	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HUE30_RS03090	COG1663	tetraacyldisaccharide 4'-kinase activity
HUE30_RS03095	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HUE30_RS03110	COG1187	pseudouridine synthase activity
HUE30_RS03130	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUE30_RS03155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUE30_RS03165	COG1522	sequence-specific DNA binding
HUE30_RS03170	COG0823	Involved in the tonB-independent uptake of proteins
HUE30_RS03170	COG1506	peptidase
HUE30_RS03175	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUE30_RS03185	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HUE30_RS03200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUE30_RS03210	COG2884	Cell division ATP-binding protein ftsE
HUE30_RS03215	COG1612	heme a metabolic process
HUE30_RS03220	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HUE30_RS03220	COG0617	tRNA 3'-terminal CCA addition
HUE30_RS03220	COG0517	IMP dehydrogenase activity
HUE30_RS03230	COG0110	maltose O-acetyltransferase activity
HUE30_RS03245	COG1215	transferase activity, transferring glycosyl groups
HUE30_RS03285	COG3022	response to hydroperoxide
HUE30_RS03290	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HUE30_RS03330	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HUE30_RS03335	COG3279	Response regulator of the LytR AlgR family
HUE30_RS03340	COG0360	Binds together with S18 to 16S ribosomal RNA
HUE30_RS03345	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUE30_RS03350	COG0359	binds to the 23S rRNA
HUE30_RS03360	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUE30_RS03370	COG2963	transposase activity
HUE30_RS03375	COG2801	Transposase and inactivated derivatives
HUE30_RS03385	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HUE30_RS03395	COG1435	thymidine kinase activity
HUE30_RS03400	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUE30_RS03405	COG1970	mechanosensitive ion channel activity
HUE30_RS03410	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HUE30_RS03415	COG0564	pseudouridine synthase activity
HUE30_RS03420	COG1012	belongs to the aldehyde dehydrogenase family
HUE30_RS03485	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUE30_RS03495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUE30_RS03500	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HUE30_RS03510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUE30_RS03520	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HUE30_RS03525	COG0215	cysteine-tRNA ligase activity
HUE30_RS03530	COG0302	gtp cyclohydrolase
HUE30_RS03535	COG0436	Aminotransferase
HUE30_RS03550	COG1845	cytochrome c oxidase, subunit III
HUE30_RS03560	COG0714	Associated with various cellular activities
HUE30_RS03565	COG1999	signal sequence binding
HUE30_RS03570	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUE30_RS03570	COG0515	serine threonine protein kinase
HUE30_RS03585	COG3256	nitric oxide reductase
HUE30_RS03590	COG2010	Cytochrome c
HUE30_RS03605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUE30_RS03625	COG4585	Histidine kinase
HUE30_RS03680	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HUE30_RS03700	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HUE30_RS03710	COG3011	Protein conserved in bacteria
HUE30_RS03715	COG1193	negative regulation of DNA recombination
HUE30_RS03720	COG1705	Flagellar rod assembly protein muramidase FlgJ
HUE30_RS03730	COG1696	Membrane protein involved in D-alanine export
HUE30_RS03740	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HUE30_RS03770	COG0813	purine-nucleoside phosphorylase activity
HUE30_RS03785	COG0022	dehydrogenase e1 component
HUE30_RS03790	COG2195	Cleaves the N-terminal amino acid of tripeptides
HUE30_RS03830	COG1595	DNA-templated transcription, initiation
HUE30_RS03835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUE30_RS03840	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HUE30_RS03910	COG3012	SEC-C Motif Domain Protein
HUE30_RS03925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUE30_RS03925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUE30_RS03930	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUE30_RS03930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUE30_RS03945	COG0517	IMP dehydrogenase activity
HUE30_RS03945	COG0516	GMP reductase activity
HUE30_RS03965	COG0009	L-threonylcarbamoyladenylate synthase
HUE30_RS03970	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HUE30_RS03985	COG1607	acyl-coa hydrolase
HUE30_RS03995	COG0799	negative regulation of ribosome biogenesis
HUE30_RS04000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUE30_RS04010	COG4589	Belongs to the CDS family
HUE30_RS04015	COG0688	phosphatidylethanolamine metabolic process
HUE30_RS04070	COG0746	molybdenum cofactor guanylyltransferase activity
HUE30_RS04090	COG0315	cyclic pyranopterin monophosphate synthase activity
HUE30_RS04090	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUE30_RS04095	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HUE30_RS04115	COG0243	molybdopterin cofactor binding
HUE30_RS04120	COG0437	4 iron, 4 sulfur cluster binding
HUE30_RS04155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUE30_RS04185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUE30_RS04190	COG2176	DNA-directed DNA polymerase activity
HUE30_RS04210	COG3158	transport of potassium into the cell
HUE30_RS04215	COG3781	membrane
HUE30_RS04245	COG0488	(ABC) transporter
HUE30_RS04255	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HUE30_RS04295	COG1575	Belongs to the MenA family. Type 1 subfamily
HUE30_RS04315	COG2195	Cleaves the N-terminal amino acid of tripeptides
HUE30_RS04335	COG1028	Short-chain dehydrogenase reductase Sdr
HUE30_RS04345	COG2801	Transposase and inactivated derivatives
HUE30_RS04350	COG2963	transposase activity
HUE30_RS04370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUE30_RS04380	COG0248	Ppx GppA phosphatase
HUE30_RS04390	COG2801	Transposase and inactivated derivatives
HUE30_RS04435	COG0285	dihydrofolate synthase activity
HUE30_RS04445	COG0848	biopolymer transport protein
HUE30_RS04470	COG2096	Adenosyltransferase
HUE30_RS04485	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HUE30_RS04505	COG0778	Nitroreductase
HUE30_RS04520	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
HUE30_RS04525	COG1648	precorrin-2 dehydrogenase activity
HUE30_RS04525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUE30_RS04535	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HUE30_RS04550	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUE30_RS04555	COG1492	cobalamin metabolic process
HUE30_RS04565	COG1797	cobyrinic acid a,c-diamide synthase activity
HUE30_RS04575	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUE30_RS04575	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUE30_RS04590	COG1674	ftsk spoiiie
HUE30_RS04600	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HUE30_RS04605	COG0640	Transcriptional regulator
HUE30_RS04630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUE30_RS04635	COG0450	alkyl hydroperoxide reductase
HUE30_RS04640	COG0753	catalase activity
HUE30_RS04645	COG0753	catalase activity
HUE30_RS04660	COG2801	Transposase and inactivated derivatives
HUE30_RS04665	COG2963	transposase activity
HUE30_RS04670	COG1764	response to oxidative stress
HUE30_RS04680	COG1309	transcriptional regulator
HUE30_RS04685	COG2342	PFAM TM1410 hypothetical-related protein
HUE30_RS04695	COG0488	(ABC) transporter
HUE30_RS04725	COG0668	transmembrane transport
HUE30_RS04740	COG3279	Response regulator of the LytR AlgR family
HUE30_RS04755	COG3275	phosphorelay sensor kinase activity
HUE30_RS04800	COG0167	dihydroorotate dehydrogenase activity
HUE30_RS04805	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HUE30_RS04830	COG1216	Glycosyl transferase, family 2
HUE30_RS04835	COG0754	glutathionylspermidine amidase activity
HUE30_RS04850	COG0706	membrane insertase activity
HUE30_RS04855	COG0504	CTP synthase activity
HUE30_RS04860	COG3530	Putative quorum-sensing-regulated virulence factor
HUE30_RS04870	COG1388	LysM domain
HUE30_RS04870	COG3942	CHAP domain
HUE30_RS04880	COG0519	Catalyzes the synthesis of GMP from XMP
HUE30_RS04880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUE30_RS04890	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUE30_RS04890	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUE30_RS04890	COG1703	isobutyryl-CoA mutase activity
HUE30_RS04915	COG1522	sequence-specific DNA binding
HUE30_RS04930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUE30_RS04935	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUE30_RS04945	COG1404	Belongs to the peptidase S8 family
HUE30_RS04950	COG0482	sulfurtransferase activity
HUE30_RS04965	COG1846	Transcriptional regulator
HUE30_RS04970	COG1024	Enoyl-CoA hydratase
HUE30_RS04970	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUE30_RS04975	COG0183	Belongs to the thiolase family
HUE30_RS04985	COG1960	acyl-CoA dehydrogenase activity
HUE30_RS05005	COG3118	belongs to the thioredoxin family
HUE30_RS05035	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUE30_RS05040	COG2234	aminopeptidase activity
HUE30_RS05050	COG0022	dehydrogenase e1 component
HUE30_RS05060	COG0346	lactoylglutathione lyase activity
HUE30_RS05065	COG0693	protein deglycase activity
HUE30_RS05100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUE30_RS05105	COG1301	dicarboxylic acid transport
HUE30_RS05110	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HUE30_RS05115	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUE30_RS05145	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUE30_RS05150	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUE30_RS05225	COG3645	SOS response
HUE30_RS05245	COG3177	Filamentation induced by cAMP protein fic
HUE30_RS05250	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HUE30_RS05255	COG0791	NLP P60 protein
HUE30_RS05260	COG0183	Belongs to the thiolase family
HUE30_RS05310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUE30_RS05315	COG0284	orotidine-5'-phosphate decarboxylase activity
HUE30_RS05325	COG2885	chlorophyll binding
HUE30_RS05325	COG3047	cAMP biosynthetic process
HUE30_RS05330	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HUE30_RS05335	COG1228	amidohydrolase
HUE30_RS05340	COG0804	urea catabolic process
HUE30_RS05345	COG0606	chelatase, subunit chli
HUE30_RS05360	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HUE30_RS05365	COG1960	acyl-CoA dehydrogenase activity
HUE30_RS05385	COG0348	domain, Protein
HUE30_RS05390	COG2010	Cytochrome c
HUE30_RS05400	COG3278	Belongs to the heme-copper respiratory oxidase family
HUE30_RS05410	COG2217	Heavy metal translocating P-type atpase
HUE30_RS05460	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HUE30_RS05485	COG0628	permease
HUE30_RS05515	COG1136	(ABC) transporter
HUE30_RS05530	COG1803	Methylglyoxal synthase
HUE30_RS05545	COG0205	6-phosphofructokinase activity
HUE30_RS05555	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HUE30_RS05570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUE30_RS05580	COG2321	neutral zinc metallopeptidase
HUE30_RS05605	COG0513	Belongs to the DEAD box helicase family
HUE30_RS05610	COG0010	Belongs to the arginase family
HUE30_RS05625	COG1266	CAAX protease self-immunity
HUE30_RS05630	COG1393	Belongs to the ArsC family
HUE30_RS05645	COG0598	Magnesium transport protein CorA
HUE30_RS05650	COG1228	amidohydrolase
HUE30_RS05665	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HUE30_RS05685	COG2814	Major facilitator Superfamily
HUE30_RS05700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUE30_RS05705	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUE30_RS05715	COG0187	DNA topoisomerase II activity
HUE30_RS05720	COG0367	asparagine synthase
HUE30_RS05730	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HUE30_RS05740	COG0513	Belongs to the DEAD box helicase family
HUE30_RS05755	COG1733	regulation of RNA biosynthetic process
HUE30_RS05760	COG1136	(ABC) transporter
HUE30_RS05765	COG0577	efflux transmembrane transporter activity
HUE30_RS05765	COG1136	(ABC) transporter
HUE30_RS05780	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HUE30_RS05785	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUE30_RS05795	COG0564	pseudouridine synthase activity
HUE30_RS05800	COG2234	aminopeptidase activity
HUE30_RS05805	COG0861	Integral membrane protein TerC family
HUE30_RS05825	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HUE30_RS05835	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUE30_RS05840	COG0116	Belongs to the methyltransferase superfamily
HUE30_RS05915	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HUE30_RS05920	COG0497	DNA recombination
HUE30_RS05945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUE30_RS05955	COG0737	Belongs to the 5'-nucleotidase family
HUE30_RS05960	COG0737	Belongs to the 5'-nucleotidase family
HUE30_RS05965	COG0438	transferase activity, transferring glycosyl groups
HUE30_RS05970	COG1472	Belongs to the glycosyl hydrolase 3 family
HUE30_RS05980	COG2181	nitrate reductase activity
HUE30_RS05980	COG0247	lactate metabolic process
HUE30_RS05985	COG2181	nitrate reductase activity
HUE30_RS05985	COG0247	lactate metabolic process
HUE30_RS05995	COG0860	N-Acetylmuramoyl-L-alanine amidase
HUE30_RS05995	COG2247	cell wall binding repeat
HUE30_RS06020	COG0443	Heat shock 70 kDa protein
HUE30_RS06035	COG2962	Rard protein
HUE30_RS06060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUE30_RS06070	COG1858	cytochrome C peroxidase
HUE30_RS06100	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUE30_RS06115	COG2996	Protein conserved in bacteria
HUE30_RS06125	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HUE30_RS06135	COG1247	-acetyltransferase
HUE30_RS06140	COG2264	protein methyltransferase activity
HUE30_RS06160	COG0105	UTP biosynthetic process
HUE30_RS06165	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HUE30_RS06180	COG1217	gtp-binding protein TYPA
HUE30_RS06185	COG0268	Binds directly to 16S ribosomal RNA
HUE30_RS06205	COG0442	prolyl-tRNA aminoacylation
HUE30_RS06220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUE30_RS06255	COG0415	Belongs to the DNA photolyase family
HUE30_RS06285	COG0702	epimerase
HUE30_RS06290	COG1028	Short-chain dehydrogenase reductase Sdr
HUE30_RS06305	COG0386	Belongs to the glutathione peroxidase family
HUE30_RS06310	COG0386	Belongs to the glutathione peroxidase family
HUE30_RS06315	COG1333	cytochrome c biogenesis protein
HUE30_RS06315	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUE30_RS06330	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HUE30_RS06340	COG0424	maF-like protein
HUE30_RS06350	COG0101	tRNA pseudouridine synthase activity
HUE30_RS06355	COG1132	(ABC) transporter
HUE30_RS06370	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HUE30_RS06385	COG3118	belongs to the thioredoxin family
HUE30_RS06390	COG0149	triose-phosphate isomerase activity
HUE30_RS06405	COG0572	uridine kinase
HUE30_RS06420	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUE30_RS06425	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUE30_RS06425	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUE30_RS06455	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUE30_RS06465	COG1690	Belongs to the RtcB family
HUE30_RS06470	COG0531	amino acid
HUE30_RS06480	COG1404	Belongs to the peptidase S8 family
HUE30_RS06485	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HUE30_RS06490	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUE30_RS06495	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HUE30_RS06500	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HUE30_RS06505	COG0673	inositol 2-dehydrogenase activity
HUE30_RS06520	COG4804	nuclease activity
HUE30_RS06525	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUE30_RS06540	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HUE30_RS06545	COG0322	excinuclease ABC activity
HUE30_RS06550	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HUE30_RS06570	COG4804	nuclease activity
HUE30_RS06595	COG0012	GTP binding
HUE30_RS06740	COG3876	Protein conserved in bacteria
HUE30_RS06745	COG0840	transmembrane signaling receptor activity
HUE30_RS06765	COG0602	queuosine metabolic process
HUE30_RS06790	COG0848	biopolymer transport protein
HUE30_RS06805	COG0433	COG0433 Predicted ATPase
HUE30_RS06815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUE30_RS06825	COG0010	Belongs to the arginase family
HUE30_RS06835	COG3844	kynureninase activity
HUE30_RS06845	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HUE30_RS06850	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUE30_RS06860	COG1490	D-aminoacyl-tRNA deacylase activity
HUE30_RS06865	COG1162	GTPase activity
HUE30_RS06870	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HUE30_RS06885	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HUE30_RS06890	COG2022	thiamine diphosphate biosynthetic process
HUE30_RS06895	COG4122	O-methyltransferase activity
HUE30_RS06900	COG0671	phosphoesterase, PA-phosphatase related
HUE30_RS06905	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUE30_RS06930	COG3340	Belongs to the peptidase S51 family
HUE30_RS06940	COG2989	Protein conserved in bacteria
HUE30_RS06960	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HUE30_RS06965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUE30_RS06975	COG1519	Transferase
HUE30_RS06975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HUE30_RS06985	COG3279	Response regulator of the LytR AlgR family
HUE30_RS06990	COG3275	phosphorelay sensor kinase activity
HUE30_RS06995	COG4717	serine-type aminopeptidase activity
HUE30_RS07045	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUE30_RS07045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUE30_RS07055	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HUE30_RS07060	COG0052	Belongs to the universal ribosomal protein uS2 family
HUE30_RS07065	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HUE30_RS07110	COG0233	cytoplasmic translational termination
HUE30_RS07115	COG0528	UMP kinase activity
HUE30_RS07120	COG0840	transmembrane signaling receptor activity
HUE30_RS07135	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HUE30_RS07160	COG0826	peptidase U32
HUE30_RS07170	COG0357	Ribosomal RNA small subunit methyltransferase G
HUE30_RS07175	COG3239	Fatty acid desaturase
HUE30_RS07180	COG0436	Aminotransferase
HUE30_RS07185	COG2801	Transposase and inactivated derivatives
HUE30_RS07200	COG1690	Belongs to the RtcB family
HUE30_RS07205	COG3541	Predicted nucleotidyltransferase
HUE30_RS07215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUE30_RS07235	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HUE30_RS07245	COG1012	belongs to the aldehyde dehydrogenase family
HUE30_RS07250	COG2967	ApaG domain
HUE30_RS07260	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUE30_RS07275	COG0427	acetyl-CoA hydrolase
HUE30_RS07295	COG2217	Heavy metal translocating P-type atpase
HUE30_RS07320	COG0017	Asparaginyl-tRNA synthetase
HUE30_RS07335	COG0475	glutathione-regulated potassium exporter activity
HUE30_RS07375	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUE30_RS07380	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HUE30_RS07405	COG0437	4 iron, 4 sulfur cluster binding
HUE30_RS07420	COG1007	ATP synthesis coupled electron transport
HUE30_RS07425	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUE30_RS07430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUE30_RS07435	COG0713	ATP synthesis coupled electron transport
HUE30_RS07440	COG0839	Belongs to the complex I subunit 6 family
HUE30_RS07445	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUE30_RS07450	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUE30_RS07455	COG1034	ATP synthesis coupled electron transport
HUE30_RS07475	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HUE30_RS07480	COG0649	NAD binding
HUE30_RS07485	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUE30_RS07490	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUE30_RS07495	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUE30_RS07500	COG1530	ribonuclease E activity
HUE30_RS07505	COG0776	regulation of translation
HUE30_RS07510	COG1194	a g-specific adenine glycosylase
HUE30_RS07515	COG0629	single-stranded DNA binding
HUE30_RS07545	COG0720	synthase
HUE30_RS07550	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HUE30_RS07555	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HUE30_RS07570	COG0084	hydrolase, TatD family'
HUE30_RS07580	COG0252	asparaginase activity
HUE30_RS07595	COG3335	DDE superfamily endonuclease
HUE30_RS07610	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HUE30_RS07620	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HUE30_RS07650	COG0463	Glycosyl transferase, family 2
HUE30_RS07655	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUE30_RS07670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HUE30_RS07680	COG0823	Involved in the tonB-independent uptake of proteins
HUE30_RS07680	COG1506	peptidase
HUE30_RS07685	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUE30_RS07695	COG0297	glycogen (starch) synthase activity
HUE30_RS07700	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HUE30_RS07705	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HUE30_RS07720	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HUE30_RS07730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUE30_RS07740	COG0667	Aldo Keto reductase
HUE30_RS07745	COG1360	Flagellar Motor Protein
HUE30_RS07750	COG0708	Exodeoxyribonuclease III
HUE30_RS07765	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HUE30_RS07770	COG2954	triphosphatase activity
HUE30_RS07775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUE30_RS07780	COG0469	pyruvate kinase activity
HUE30_RS07790	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUE30_RS07795	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HUE30_RS07810	COG2151	metal-sulfur cluster biosynthetic enzyme
HUE30_RS07815	COG2166	iron-sulfur cluster assembly
HUE30_RS07825	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUE30_RS07880	COG2304	oxidoreductase activity
HUE30_RS07900	COG0714	Associated with various cellular activities
HUE30_RS07910	COG0571	ribonuclease III activity
HUE30_RS07915	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUE30_RS07920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUE30_RS07925	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUE30_RS07930	COG0328	RNA-DNA hybrid ribonuclease activity
HUE30_RS07935	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HUE30_RS07945	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HUE30_RS07960	COG1381	Involved in DNA repair and RecF pathway recombination
HUE30_RS07975	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUE30_RS07985	COG0626	cystathionine gamma-synthase activity
HUE30_RS07990	COG1012	belongs to the aldehyde dehydrogenase family
HUE30_RS08020	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUE30_RS08055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUE30_RS08060	COG0501	Belongs to the peptidase M48B family
HUE30_RS08070	COG0316	Belongs to the HesB IscA family
HUE30_RS08075	COG0719	Fe-S assembly protein
HUE30_RS08080	COG0655	NAD(P)H dehydrogenase (quinone) activity
HUE30_RS08085	COG0396	ATPase activity
HUE30_RS08095	COG0719	Fe-S assembly protein
HUE30_RS08110	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HUE30_RS08120	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HUE30_RS08130	COG1979	alcohol dehydrogenase
HUE30_RS08135	COG1051	belongs to the nudix hydrolase family
HUE30_RS08135	COG1056	cytidyltransferase-related domain
HUE30_RS08140	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUE30_RS08175	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HUE30_RS08200	COG3335	DDE superfamily endonuclease
HUE30_RS08215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HUE30_RS08225	COG0194	GDP metabolic process
HUE30_RS08250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUE30_RS08255	COG0156	8-amino-7-oxononanoate synthase activity
HUE30_RS08270	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HUE30_RS08280	COG4771	TonB-dependent receptor
HUE30_RS08285	COG2137	regulation of response to DNA damage stimulus
HUE30_RS08350	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HUE30_RS08370	COG0489	protein tyrosine kinase activity
HUE30_RS08380	COG0492	ferredoxin-NADP+ reductase activity
HUE30_RS08390	COG2217	Heavy metal translocating P-type atpase
HUE30_RS08400	COG0594	ribonuclease P activity
HUE30_RS08435	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUE30_RS08445	COG2824	Alkylphosphonate utilization operon protein PhnA
HUE30_RS08475	COG5002	protein histidine kinase activity
HUE30_RS08480	COG0745	RESPONSE REGULATOR receiver
HUE30_RS08485	COG4206	TonB-dependent receptor
HUE30_RS08485	COG1629	transport
HUE30_RS08515	COG0439	Biotin carboxylase
HUE30_RS08520	COG0511	ligase activity, forming carbon-carbon bonds
HUE30_RS08525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUE30_RS08530	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HUE30_RS08540	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HUE30_RS08545	COG0307	riboflavin synthase, alpha
HUE30_RS08550	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HUE30_RS08555	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HUE30_RS08560	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUE30_RS08565	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HUE30_RS08570	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUE30_RS08575	COG0356	it plays a direct role in the translocation of protons across the membrane
HUE30_RS08605	COG1017	nitric oxide dioxygenase activity
HUE30_RS08605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUE30_RS08625	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HUE30_RS08640	COG0151	Belongs to the GarS family
HUE30_RS08650	COG1215	transferase activity, transferring glycosyl groups
HUE30_RS08685	COG3590	peptidase
HUE30_RS08690	COG1999	signal sequence binding
HUE30_RS08700	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HUE30_RS08700	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HUE30_RS08710	COG0750	zinc metalloprotease
HUE30_RS08750	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HUE30_RS08760	COG0792	nuclease activity
HUE30_RS08765	COG1619	proteins homologs of microcin C7 resistance protein MccF
HUE30_RS08770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUE30_RS08770	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUE30_RS08775	COG1528	Iron-storage protein
HUE30_RS08785	COG0784	Response regulator, receiver
HUE30_RS08795	COG5002	protein histidine kinase activity
HUE30_RS08805	COG2205	protein histidine kinase activity
HUE30_RS08815	COG3279	Response regulator of the LytR AlgR family
HUE30_RS08860	COG0745	RESPONSE REGULATOR receiver
HUE30_RS08865	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HUE30_RS08885	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HUE30_RS08890	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HUE30_RS08900	COG1774	PSP1 C-terminal conserved region
HUE30_RS08910	COG0826	peptidase U32
HUE30_RS08915	COG1054	Belongs to the UPF0176 family
HUE30_RS08920	COG2963	transposase activity
HUE30_RS08930	COG2801	Transposase and inactivated derivatives
HUE30_RS08940	COG0629	single-stranded DNA binding
HUE30_RS08955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUE30_RS08960	COG0697	spore germination
HUE30_RS08970	COG1607	acyl-coa hydrolase
HUE30_RS08980	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUE30_RS08980	COG0758	DNA mediated transformation
HUE30_RS08990	COG3179	chitinase
HUE30_RS09005	COG3335	DDE superfamily endonuclease
HUE30_RS09030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUE30_RS09035	COG1522	sequence-specific DNA binding
HUE30_RS09040	COG0165	Argininosuccinate lyase
HUE30_RS09050	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HUE30_RS09055	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUE30_RS09065	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HUE30_RS09070	COG0137	argininosuccinate synthase activity
HUE30_RS09145	COG2860	membrane
HUE30_RS09160	COG0557	exoribonuclease II activity
HUE30_RS09195	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUE30_RS09210	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUE30_RS09220	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HUE30_RS09225	COG0445	tRNA wobble uridine modification
HUE30_RS09245	COG0470	DNA polymerase III
HUE30_RS09280	COG0126	phosphoglycerate kinase activity
HUE30_RS09285	COG1388	LysM domain
HUE30_RS09285	COG0791	NLP P60 protein
HUE30_RS09290	COG2153	protein acetylation
HUE30_RS09305	COG0495	leucyl-tRNA aminoacylation
HUE30_RS09310	COG0671	phosphoesterase, PA-phosphatase related
HUE30_RS09320	COG2177	Part of the ABC transporter FtsEX involved in
HUE30_RS09330	COG1968	undecaprenyl-diphosphatase activity
HUE30_RS09335	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HUE30_RS09345	COG0519	Catalyzes the synthesis of GMP from XMP
HUE30_RS09355	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HUE30_RS09370	COG0352	thiamine-phosphate diphosphorylase activity
HUE30_RS09375	COG2022	thiamine diphosphate biosynthetic process
HUE30_RS09385	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HUE30_RS09390	COG0501	Belongs to the peptidase M48B family
HUE30_RS09410	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HUE30_RS09420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUE30_RS09425	COG3852	Histidine kinase
HUE30_RS09440	COG0793	Belongs to the peptidase S41A family
HUE30_RS09450	COG1522	sequence-specific DNA binding
HUE30_RS09460	COG2363	Small membrane protein
HUE30_RS09465	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HUE30_RS09470	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HUE30_RS09475	COG0481	GTPase activity
HUE30_RS09490	COG0531	amino acid
HUE30_RS09495	COG1752	Esterase of the alpha-beta hydrolase superfamily
HUE30_RS09500	COG0322	excinuclease ABC activity
HUE30_RS09505	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HUE30_RS09515	COG1074	ATP-dependent DNA helicase activity
HUE30_RS09520	COG0156	8-amino-7-oxononanoate synthase activity
HUE30_RS09535	COG2267	carboxylic ester hydrolase activity
HUE30_RS09545	COG0006	proline dipeptidase activity
HUE30_RS09565	COG1053	succinate dehydrogenase
HUE30_RS09570	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUE30_RS09595	COG3621	Patatin-like phospholipase
HUE30_RS09650	COG1876	peptidase activity
HUE30_RS09670	COG0423	glycine-tRNA ligase activity
HUE30_RS09675	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HUE30_RS09725	COG4104	PAAR repeat-containing protein
HUE30_RS09725	COG3209	COG3209 Rhs family protein
HUE30_RS09770	COG4771	TonB-dependent receptor
HUE30_RS09780	COG1914	H( )-stimulated, divalent metal cation uptake system
HUE30_RS09815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUE30_RS09825	COG0113	porphobilinogen synthase activity
HUE30_RS09835	COG0408	coproporphyrinogen oxidase activity
HUE30_RS09845	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HUE30_RS09855	COG0181	hydroxymethylbilane synthase activity
HUE30_RS09860	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HUE30_RS09870	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HUE30_RS09875	COG1981	membrane
HUE30_RS09880	COG5000	phosphorelay sensor kinase activity
HUE30_RS09885	COG1024	Enoyl-CoA hydratase
HUE30_RS09890	COG1418	mRNA catabolic process
HUE30_RS09925	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HUE30_RS09930	COG0756	dUTP diphosphatase activity
HUE30_RS09945	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HUE30_RS09960	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUE30_RS09965	COG2239	Acts as a magnesium transporter
HUE30_RS09970	COG2963	transposase activity
HUE30_RS09975	COG2801	Transposase and inactivated derivatives
HUE30_RS09980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUE30_RS09995	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUE30_RS10015	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HUE30_RS10020	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUE30_RS10025	COG0567	Dehydrogenase, E1 component
HUE30_RS10040	COG2814	Major facilitator Superfamily
HUE30_RS10045	COG3540	Alkaline phosphatase
HUE30_RS10060	COG1028	Short-chain dehydrogenase reductase Sdr
HUE30_RS10095	COG3335	DDE superfamily endonuclease
HUE30_RS10180	COG0542	response to heat
HUE30_RS10240	COG1459	type II secretion system
HUE30_RS10370	COG0358	DNA primase activity
HUE30_RS10400	COG0358	DNA primase activity
HUE30_RS10455	COG2801	Transposase and inactivated derivatives
HUE30_RS10525	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HUE30_RS10565	COG0180	Tryptophanyl-tRNA synthetase
HUE30_RS10575	COG3483	tryptophan 2,3-dioxygenase activity
HUE30_RS10580	COG0166	Belongs to the GPI family
HUE30_RS10590	COG2315	Protein conserved in bacteria
HUE30_RS10605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUE30_RS10610	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HUE30_RS10635	COG0193	aminoacyl-tRNA hydrolase activity
HUE30_RS10640	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HUE30_RS10645	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUE30_RS10685	COG2003	Belongs to the UPF0758 family
HUE30_RS10770	COG1960	acyl-CoA dehydrogenase activity
HUE30_RS10780	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HUE30_RS10785	COG0346	lactoylglutathione lyase activity
HUE30_RS10805	COG0196	riboflavin kinase activity
HUE30_RS10810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUE30_RS10820	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HUE30_RS10830	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HUE30_RS10840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUE30_RS10850	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
HUE30_RS10855	COG3185	4-Hydroxyphenylpyruvate dioxygenase
HUE30_RS10860	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HUE30_RS10865	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HUE30_RS10870	COG0228	four-way junction DNA binding
HUE30_RS10900	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HUE30_RS10920	COG1278	Cold shock
HUE30_RS10925	COG0590	tRNA wobble adenosine to inosine editing
HUE30_RS10930	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUE30_RS10940	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HUE30_RS10970	COG2095	MarC family integral membrane protein
HUE30_RS11000	COG0589	response to stress
HUE30_RS11005	COG0779	Required for maturation of 30S ribosomal subunits
HUE30_RS11010	COG0195	Participates in both transcription termination and antitermination
HUE30_RS11010	COG2251	uridine kinase activity
HUE30_RS11015	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HUE30_RS11020	COG0531	amino acid
HUE30_RS11025	COG2255	four-way junction helicase activity
HUE30_RS11030	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HUE30_RS11040	COG0632	four-way junction helicase activity
HUE30_RS11050	COG0509	glycine decarboxylation via glycine cleavage system
HUE30_RS11060	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HUE30_RS11085	COG0109	protoheme IX farnesyltransferase activity
HUE30_RS11090	COG1845	cytochrome c oxidase, subunit III
HUE30_RS11110	COG1999	signal sequence binding
HUE30_RS11115	COG2322	membrane
HUE30_RS11135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUE30_RS11140	COG1214	PFAM Peptidase M22, glycoprotease
HUE30_RS11145	COG0668	transmembrane transport
HUE30_RS11160	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HUE30_RS11165	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HUE30_RS11185	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUE30_RS11195	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUE30_RS11205	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HUE30_RS11220	COG0544	peptidyl-prolyl cis-trans isomerase activity
HUE30_RS11225	COG0740	serine-type endopeptidase activity
HUE30_RS11230	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HUE30_RS11250	COG0616	signal peptide processing
HUE30_RS11255	COG1428	Deoxynucleoside kinase
HUE30_RS11260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUE30_RS11270	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HUE30_RS11320	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HUE30_RS11340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUE30_RS11370	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HUE30_RS11375	COG0501	Belongs to the peptidase M48B family
HUE30_RS11385	COG0460	homoserine dehydrogenase
HUE30_RS11385	COG0527	aspartate kinase activity
HUE30_RS11410	COG2081	HI0933 family
HUE30_RS11430	COG1187	pseudouridine synthase activity
HUE30_RS11455	COG3335	DDE superfamily endonuclease
HUE30_RS11465	COG0793	Belongs to the peptidase S41A family
HUE30_RS11470	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HUE30_RS11480	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUE30_RS11485	COG2333	competence protein COMEC
HUE30_RS11485	COG0658	competence protein
HUE30_RS11500	COG3104	oligopeptide transport
HUE30_RS11540	COG0772	Belongs to the SEDS family
HUE30_RS11545	COG0768	penicillin binding
HUE30_RS11560	COG1077	Cell shape determining protein MreB Mrl
HUE30_RS11565	COG0450	alkyl hydroperoxide reductase
HUE30_RS11575	COG0138	bifunctional purine biosynthesis protein purh
HUE30_RS11580	COG1136	(ABC) transporter
HUE30_RS11580	COG0577	efflux transmembrane transporter activity
HUE30_RS11585	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HUE30_RS11610	COG2226	methyltransferase
HUE30_RS11615	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HUE30_RS11625	COG0022	dehydrogenase e1 component
HUE30_RS11625	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUE30_RS11630	COG2086	electron transfer activity
HUE30_RS11635	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HUE30_RS11645	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HUE30_RS11655	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HUE30_RS11660	COG1428	Deoxynucleoside kinase
HUE30_RS11670	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HUE30_RS11695	COG1215	transferase activity, transferring glycosyl groups
HUE30_RS11715	COG3335	DDE superfamily endonuclease
HUE30_RS11735	COG0460	homoserine dehydrogenase
HUE30_RS11735	COG0527	aspartate kinase activity
HUE30_RS11740	COG0646	methionine synthase
HUE30_RS11740	COG1410	methionine synthase
HUE30_RS11770	COG3335	DDE superfamily endonuclease
HUE30_RS11780	COG0358	DNA primase activity
HUE30_RS11795	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HUE30_RS11815	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HUE30_RS11825	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HUE30_RS11835	COG2001	Belongs to the MraZ family
HUE30_RS11840	COG0275	rRNA processing
HUE30_RS11850	COG0768	penicillin binding
HUE30_RS11855	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HUE30_RS11860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUE30_RS11865	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HUE30_RS11870	COG0772	Belongs to the SEDS family
HUE30_RS11875	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HUE30_RS11880	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUE30_RS11895	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HUE30_RS11900	COG1610	YqeY-like protein
HUE30_RS11925	COG2963	transposase activity
HUE30_RS11930	COG2801	Transposase and inactivated derivatives
HUE30_RS11985	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUE30_RS11990	COG1185	polyribonucleotide nucleotidyltransferase activity
HUE30_RS11995	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HUE30_RS12035	COG0659	secondary active sulfate transmembrane transporter activity
HUE30_RS12045	COG0288	reversible hydration of carbon dioxide
HUE30_RS12050	COG0586	Pfam SNARE associated Golgi protein
HUE30_RS12060	COG3002	Belongs to the UPF0753 family
HUE30_RS12065	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUE30_RS12070	COG0659	secondary active sulfate transmembrane transporter activity
HUE30_RS12105	COG1028	Short-chain dehydrogenase reductase Sdr
HUE30_RS12115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUE30_RS12130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUE30_RS12135	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HUE30_RS12155	COG1131	(ABC) transporter
HUE30_RS12160	COG0842	Transport permease protein
HUE30_RS12170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUE30_RS12185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUE30_RS12215	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HUE30_RS12285	COG4115	mRNA cleavage
HUE30_RS12315	COG0459	protein refolding
HUE30_RS12320	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HUE30_RS12350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUE30_RS12365	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUE30_RS12420	COG0488	(ABC) transporter
HUE30_RS12430	COG3420	alginic acid biosynthetic process
HUE30_RS12440	COG1522	sequence-specific DNA binding
HUE30_RS12455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUE30_RS12460	COG0277	FAD linked oxidase domain protein
HUE30_RS12460	COG0247	lactate metabolic process
HUE30_RS12465	COG0076	glutamate decarboxylase activity
HUE30_RS12550	COG2801	Transposase and inactivated derivatives
HUE30_RS12555	COG2963	transposase activity
HUE30_RS12560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUE30_RS12565	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUE30_RS12565	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUE30_RS12570	COG2373	Large extracellular alpha-helical protein
HUE30_RS12575	COG4953	penicillin-binding protein 1C
HUE30_RS12590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUE30_RS12620	COG1510	regulation of RNA biosynthetic process
HUE30_RS12625	COG2949	membrane
HUE30_RS12635	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HUE30_RS12650	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HUE30_RS12660	COG0563	adenylate kinase activity
HUE30_RS12665	COG1253	flavin adenine dinucleotide binding
HUE30_RS12670	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HUE30_RS12680	COG4935	Belongs to the peptidase S8 family
HUE30_RS12680	COG2234	aminopeptidase activity
HUE30_RS12715	COG3591	Belongs to the peptidase S1B family
HUE30_RS12725	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUE30_RS12755	COG3486	L-lysine 6-monooxygenase (NADPH) activity
HUE30_RS12760	COG0076	glutamate decarboxylase activity
HUE30_RS12785	COG2003	Belongs to the UPF0758 family
HUE30_RS12790	COG1136	(ABC) transporter
HUE30_RS12805	COG0546	phosphoglycolate phosphatase activity
HUE30_RS12825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HUE30_RS12835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUE30_RS12845	COG1629	transport
HUE30_RS12845	COG4206	TonB-dependent receptor
HUE30_RS12855	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HUE30_RS12860	COG0049	tRNA binding
HUE30_RS12865	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUE30_RS12870	COG0051	transcription antitermination factor activity, RNA binding
HUE30_RS12875	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HUE30_RS12880	COG0088	Forms part of the polypeptide exit tunnel
HUE30_RS12885	COG0089	rRNA binding
HUE30_RS12890	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HUE30_RS12895	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HUE30_RS12900	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HUE30_RS12905	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HUE30_RS12910	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HUE30_RS12915	COG0255	Belongs to the universal ribosomal protein uL29 family
HUE30_RS12920	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HUE30_RS12925	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HUE30_RS12930	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HUE30_RS12935	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HUE30_RS12940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUE30_RS12945	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HUE30_RS12950	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HUE30_RS12960	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HUE30_RS12965	COG1841	ribosomal large subunit assembly
HUE30_RS12970	COG0200	Binds to the 23S rRNA
HUE30_RS12980	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HUE30_RS12985	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HUE30_RS12990	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HUE30_RS12995	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HUE30_RS13000	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HUE30_RS13005	COG0202	RNA polymerase activity
HUE30_RS13010	COG0203	ribosomal protein L17
HUE30_RS13020	COG0148	phosphopyruvate hydratase activity
HUE30_RS13030	COG2963	transposase activity
HUE30_RS13035	COG2801	Transposase and inactivated derivatives
HUE30_RS13140	COG0010	Belongs to the arginase family
HUE30_RS13150	COG2095	MarC family integral membrane protein
HUE30_RS13165	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUE30_RS13175	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HUE30_RS13185	COG0489	protein tyrosine kinase activity
HUE30_RS13185	COG3206	protein involved in exopolysaccharide biosynthesis
HUE30_RS13190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUE30_RS13195	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HUE30_RS13200	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUE30_RS13220	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HUE30_RS13235	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUE30_RS13265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUE30_RS13270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HUE30_RS13275	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HUE30_RS13280	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HUE30_RS13300	COG3335	DDE superfamily endonuclease
HUE30_RS13325	COG4464	protein tyrosine phosphatase activity
HUE30_RS13345	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HUE30_RS13350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUE30_RS13365	COG0438	transferase activity, transferring glycosyl groups
HUE30_RS13390	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HUE30_RS13395	COG2089	acid synthase
HUE30_RS13410	COG0438	transferase activity, transferring glycosyl groups
HUE30_RS13410	COG0297	glycogen (starch) synthase activity
HUE30_RS13435	COG0438	transferase activity, transferring glycosyl groups
HUE30_RS13450	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HUE30_RS13505	COG1137	ATPase activity
HUE30_RS13515	COG0805	protein transport
HUE30_RS13520	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HUE30_RS13520	COG0517	IMP dehydrogenase activity
HUE30_RS13525	COG0514	ATP-dependent DNA helicase (RecQ)
HUE30_RS13540	COG3328	transposase activity
HUE30_RS13625	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HUE30_RS13630	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HUE30_RS13640	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HUE30_RS13680	COG0513	Belongs to the DEAD box helicase family
HUE30_RS13710	COG1702	phosphate starvation-inducible protein PhoH
HUE30_RS13725	COG1959	2 iron, 2 sulfur cluster binding
HUE30_RS13730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUE30_RS13730	COG1017	nitric oxide dioxygenase activity
HUE30_RS13735	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HUE30_RS13760	COG1363	Peptidase, m42
HUE30_RS13855	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HUE30_RS13860	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUE30_RS13875	COG0295	cytidine deaminase activity
HUE30_RS13880	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HUE30_RS13930	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUE30_RS13935	COG1215	transferase activity, transferring glycosyl groups
HUE30_RS13945	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUE30_RS13950	COG4942	peptidase
HUE30_RS13965	COG1704	LemA family
HUE30_RS13975	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HUE30_RS13990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUE30_RS14000	COG3938	Belongs to the proline racemase family
HUE30_RS14005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUE30_RS14015	COG1160	GTP binding
HUE30_RS14035	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HUE30_RS14060	COG1132	(ABC) transporter
HUE30_RS14085	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUE30_RS14090	COG3186	Phenylalanine-4-hydroxylase
HUE30_RS14095	COG2346	COG2346, Truncated hemoglobins
HUE30_RS14105	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HUE30_RS14125	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HUE30_RS14135	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUE30_RS14145	COG4263	nitrous-oxide reductase activity
HUE30_RS14185	COG3335	DDE superfamily endonuclease
HUE30_RS14245	COG1858	cytochrome C peroxidase
HUE30_RS14255	COG4774	siderophore transport
HUE30_RS14270	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUE30_RS14285	COG0321	lipoyl(octanoyl) transferase activity
HUE30_RS14290	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HUE30_RS14295	COG4771	TonB-dependent receptor
HUE30_RS14330	COG1960	acyl-CoA dehydrogenase activity
HUE30_RS14335	COG0492	ferredoxin-NADP+ reductase activity
HUE30_RS14340	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HUE30_RS14345	COG4974	Belongs to the 'phage' integrase family
HUE30_RS14370	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HUE30_RS14390	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HUE30_RS14395	COG0081	regulation of translation
HUE30_RS14400	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HUE30_RS14405	COG0222	ribosome binding
HUE30_RS14410	COG0085	RNA polymerase activity
HUE30_RS14415	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HUE30_RS14430	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HUE30_RS14435	COG5002	protein histidine kinase activity
HUE30_RS14435	COG2198	Histidine kinase
HUE30_RS14435	COG0784	Response regulator, receiver
HUE30_RS14470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUE30_RS14475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUE30_RS14485	COG0714	Associated with various cellular activities
HUE30_RS14525	COG1515	deoxyribonuclease V activity
HUE30_RS14535	COG1388	LysM domain
HUE30_RS14535	COG0791	NLP P60 protein
HUE30_RS14565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUE30_RS14570	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HUE30_RS14580	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HUE30_RS14590	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA