locus-tag	class	description
F0T65_RS00005	COG0457	Tetratricopeptide repeat
F0T65_RS00015	COG5434	Belongs to the glycosyl hydrolase 28 family
F0T65_RS00025	COG0673	inositol 2-dehydrogenase activity
F0T65_RS00045	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F0T65_RS00045	COG0519	Catalyzes the synthesis of GMP from XMP
F0T65_RS00060	COG0484	heat shock protein binding
F0T65_RS00075	COG0038	chloride channel
F0T65_RS00080	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
F0T65_RS00090	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F0T65_RS00095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F0T65_RS00140	COG3537	Alpha-1,2-mannosidase
F0T65_RS00155	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
F0T65_RS00165	COG0174	glutamine synthetase
F0T65_RS00250	COG1703	isobutyryl-CoA mutase activity
F0T65_RS00250	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F0T65_RS00250	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F0T65_RS00290	COG0788	formyltetrahydrofolate deformylase activity
F0T65_RS00300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F0T65_RS00305	COG0284	orotidine-5'-phosphate decarboxylase activity
F0T65_RS00310	COG0783	Belongs to the Dps family
F0T65_RS00325	COG0784	Response regulator, receiver
F0T65_RS00330	COG4251	negative regulation of phosphorylation
F0T65_RS00370	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
F0T65_RS00495	COG2223	nitrite transmembrane transporter activity
F0T65_RS00500	COG4771	TonB-dependent receptor
F0T65_RS00530	COG0525	valine-tRNA ligase activity
F0T65_RS00545	COG2885	chlorophyll binding
F0T65_RS00570	COG0302	gtp cyclohydrolase
F0T65_RS00580	COG0215	cysteine-tRNA ligase activity
F0T65_RS00585	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
F0T65_RS00590	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
F0T65_RS00600	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F0T65_RS00605	COG0039	L-malate dehydrogenase activity
F0T65_RS00610	COG0187	DNA topoisomerase II activity
F0T65_RS00615	COG0367	asparagine synthase
F0T65_RS00620	COG0367	asparagine synthase
F0T65_RS00630	COG3153	acetyltransferase
F0T65_RS00640	COG0384	phenazine biosynthesis protein PhzF
F0T65_RS00650	COG2884	Cell division ATP-binding protein ftsE
F0T65_RS00660	COG0463	Glycosyl transferase, family 2
F0T65_RS00660	COG1216	Glycosyl transferase, family 2
F0T65_RS00675	COG1216	Glycosyl transferase, family 2
F0T65_RS00695	COG2860	membrane
F0T65_RS00730	COG0714	Associated with various cellular activities
F0T65_RS00755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F0T65_RS00760	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F0T65_RS00770	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
F0T65_RS00775	COG0494	nUDIX hydrolase
F0T65_RS00810	COG0516	GMP reductase activity
F0T65_RS00810	COG0517	IMP dehydrogenase activity
F0T65_RS00845	COG0167	dihydroorotate dehydrogenase activity
F0T65_RS00870	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F0T65_RS00875	COG2195	Cleaves the N-terminal amino acid of tripeptides
F0T65_RS00885	COG1862	Preprotein translocase
F0T65_RS00890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F0T65_RS00900	COG1132	(ABC) transporter
F0T65_RS00920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0T65_RS00935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F0T65_RS00945	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F0T65_RS00950	COG2814	Major facilitator Superfamily
F0T65_RS00980	COG0336	Belongs to the RNA methyltransferase TrmD family
F0T65_RS00995	COG0335	large ribosomal subunit rRNA binding
F0T65_RS01040	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
F0T65_RS01050	COG0596	Alpha beta hydrolase
F0T65_RS01070	COG4948	Mandelate Racemase Muconate Lactonizing
F0T65_RS01085	COG0045	succinate-CoA ligase (ADP-forming) activity
F0T65_RS01090	COG0067	glutamate synthase
F0T65_RS01090	COG0070	glutamate synthase
F0T65_RS01090	COG0069	glutamate synthase activity
F0T65_RS01240	COG0758	DNA mediated transformation
F0T65_RS01340	COG3179	chitinase
F0T65_RS01460	COG1191	sigma factor activity
F0T65_RS01485	COG0673	inositol 2-dehydrogenase activity
F0T65_RS01490	COG0004	ammonium transporteR
F0T65_RS01500	COG0037	tRNA processing
F0T65_RS01505	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F0T65_RS01520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F0T65_RS01545	COG0531	amino acid
F0T65_RS01545	COG0531	amino acid
F0T65_RS01550	COG0247	lactate metabolic process
F0T65_RS01550	COG0277	FAD linked oxidase domain protein
F0T65_RS01565	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
F0T65_RS01570	COG1649	PFAM Uncharacterised BCR, COG1649
F0T65_RS01575	COG2211	Major facilitator Superfamily
F0T65_RS01590	COG1472	Belongs to the glycosyl hydrolase 3 family
F0T65_RS01595	COG0450	alkyl hydroperoxide reductase
F0T65_RS01620	COG1674	ftsk spoiiie
F0T65_RS01635	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F0T65_RS01635	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F0T65_RS01650	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
F0T65_RS01655	COG0346	lactoylglutathione lyase activity
F0T65_RS01660	COG4221	oxidoreductase activity
F0T65_RS01710	COG2091	lysine biosynthetic process via aminoadipic acid
F0T65_RS01715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0T65_RS01735	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
F0T65_RS01775	COG0463	Glycosyl transferase, family 2
F0T65_RS01800	COG3537	Alpha-1,2-mannosidase
F0T65_RS01820	COG4771	TonB-dependent receptor
F0T65_RS01835	COG1785	Belongs to the alkaline phosphatase family
F0T65_RS01840	COG0702	epimerase
F0T65_RS01845	COG4771	TonB-dependent receptor
F0T65_RS01860	COG0456	acetyltransferase
F0T65_RS01860	COG1846	Transcriptional regulator
F0T65_RS01985	COG1876	peptidase activity
F0T65_RS02040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0T65_RS02045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0T65_RS02055	COG4206	TonB-dependent receptor
F0T65_RS02055	COG1629	transport
F0T65_RS02075	COG0583	DNA-binding transcription factor activity
F0T65_RS02080	COG2115	Belongs to the xylose isomerase family
F0T65_RS02100	COG1028	Short-chain dehydrogenase reductase Sdr
F0T65_RS02105	COG1881	PFAM PEBP family protein
F0T65_RS02160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0T65_RS02170	COG3655	Transcriptional regulator
F0T65_RS02175	COG1131	(ABC) transporter
F0T65_RS02190	COG2204	response regulator
F0T65_RS02205	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
F0T65_RS02210	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
F0T65_RS02215	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
F0T65_RS02225	COG2205	protein histidine kinase activity
F0T65_RS02245	COG0671	phosphoesterase, PA-phosphatase related
F0T65_RS02250	COG1396	sequence-specific DNA binding
F0T65_RS02255	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F0T65_RS02260	COG0587	DNA-directed DNA polymerase activity
F0T65_RS02265	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F0T65_RS02265	COG1199	ATP-dependent helicase activity
F0T65_RS02285	COG0531	amino acid
F0T65_RS02295	COG4106	trans-aconitate 2-methyltransferase activity
F0T65_RS02300	COG5002	protein histidine kinase activity
F0T65_RS02310	COG0791	NLP P60 protein
F0T65_RS02320	COG1049	propionate catabolic process, 2-methylcitrate cycle
F0T65_RS02325	COG0714	Associated with various cellular activities
F0T65_RS02330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0T65_RS02335	COG1874	Beta-galactosidase
F0T65_RS02335	COG0366	Alpha amylase catalytic
F0T65_RS02340	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
F0T65_RS02355	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
F0T65_RS02360	COG0085	RNA polymerase activity
F0T65_RS02365	COG0222	ribosome binding
F0T65_RS02370	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
F0T65_RS02375	COG0081	regulation of translation
F0T65_RS02380	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
F0T65_RS02400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
F0T65_RS02425	COG4974	Belongs to the 'phage' integrase family
F0T65_RS02430	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F0T65_RS02435	COG1960	acyl-CoA dehydrogenase activity
F0T65_RS02445	COG0531	amino acid
F0T65_RS02460	COG2176	DNA-directed DNA polymerase activity
F0T65_RS02480	COG4771	TonB-dependent receptor
F0T65_RS02485	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
F0T65_RS02495	COG0321	lipoyl(octanoyl) transferase activity
F0T65_RS02515	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
F0T65_RS02525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F0T65_RS02540	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
F0T65_RS02545	COG0791	NLP P60 protein
F0T65_RS02545	COG1388	LysM domain
F0T65_RS02550	COG2515	1-aminocyclopropane-1-carboxylate deaminase
F0T65_RS02575	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F0T65_RS02595	COG3186	Phenylalanine-4-hydroxylase
F0T65_RS02660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F0T65_RS02665	COG0739	heme binding
F0T65_RS02670	COG0789	Transcriptional regulator
F0T65_RS02675	COG1704	LemA family
F0T65_RS02690	COG1959	2 iron, 2 sulfur cluster binding
F0T65_RS02715	COG1160	GTP binding
F0T65_RS02720	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F0T65_RS02765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F0T65_RS02785	COG1028	Short-chain dehydrogenase reductase Sdr
F0T65_RS02820	COG0252	asparaginase activity
F0T65_RS02850	COG2267	carboxylic ester hydrolase activity
F0T65_RS02915	COG4221	oxidoreductase activity
F0T65_RS02955	COG1597	lipid kinase activity
F0T65_RS02965	COG0488	(ABC) transporter
F0T65_RS03000	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F0T65_RS03015	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F0T65_RS03045	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
F0T65_RS03055	COG0459	protein refolding
F0T65_RS03065	COG0659	secondary active sulfate transmembrane transporter activity
F0T65_RS03115	COG3279	Response regulator of the LytR AlgR family
F0T65_RS03155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F0T65_RS03160	COG1395	domain, Protein
F0T65_RS03165	COG2207	Transcriptional regulator
F0T65_RS03185	COG1610	YqeY-like protein
F0T65_RS03190	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F0T65_RS03205	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F0T65_RS03215	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
F0T65_RS03220	COG0772	Belongs to the SEDS family
F0T65_RS03225	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
F0T65_RS03230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F0T65_RS03235	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F0T65_RS03240	COG0768	penicillin binding
F0T65_RS03250	COG0275	rRNA processing
F0T65_RS03255	COG2001	Belongs to the MraZ family
F0T65_RS03265	COG0218	Necessary for normal cell division and for the maintenance of normal septation
F0T65_RS03285	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
F0T65_RS03295	COG0358	DNA primase activity
F0T65_RS03325	COG0820	rRNA (adenine-C2-)-methyltransferase activity
F0T65_RS03355	COG4122	O-methyltransferase activity
F0T65_RS03365	COG0671	phosphoesterase, PA-phosphatase related
F0T65_RS03370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F0T65_RS03400	COG3340	Belongs to the peptidase S51 family
F0T65_RS03420	COG2989	Protein conserved in bacteria
F0T65_RS03430	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
F0T65_RS03435	COG2733	membrane
F0T65_RS03455	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
F0T65_RS03465	COG2967	ApaG domain
F0T65_RS03470	COG1012	belongs to the aldehyde dehydrogenase family
F0T65_RS03480	COG0357	Ribosomal RNA small subunit methyltransferase G
F0T65_RS03485	COG3239	Fatty acid desaturase
F0T65_RS03490	COG0436	Aminotransferase
F0T65_RS03505	COG0826	peptidase U32
F0T65_RS03515	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
F0T65_RS03530	COG2224	Isocitrate lyase
F0T65_RS03535	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F0T65_RS03550	COG1741	Belongs to the pirin family
F0T65_RS03560	COG2353	YceI-like domain
F0T65_RS03575	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F0T65_RS03590	COG0697	spore germination
F0T65_RS03595	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F0T65_RS03630	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
F0T65_RS03640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F0T65_RS03650	COG1428	Deoxynucleoside kinase
F0T65_RS03655	COG0616	signal peptide processing
F0T65_RS03695	COG0560	Phosphoserine phosphatase
F0T65_RS03695	COG3830	Belongs to the UPF0237 family
F0T65_RS03725	COG1917	Cupin 2, conserved barrel domain protein
F0T65_RS03725	COG4977	sequence-specific DNA binding
F0T65_RS03730	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
F0T65_RS03740	COG0544	peptidyl-prolyl cis-trans isomerase activity
F0T65_RS03745	COG1950	PFAM Membrane protein of
F0T65_RS03750	COG0596	Alpha beta hydrolase
F0T65_RS03770	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F0T65_RS03780	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
F0T65_RS03790	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F0T65_RS03810	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
F0T65_RS03840	COG3275	phosphorelay sensor kinase activity
F0T65_RS03850	COG3279	Response regulator of the LytR AlgR family
F0T65_RS03855	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F0T65_RS03880	COG1214	PFAM Peptidase M22, glycoprotease
F0T65_RS03900	COG0577	efflux transmembrane transporter activity
F0T65_RS03900	COG1136	(ABC) transporter
F0T65_RS03905	COG0577	efflux transmembrane transporter activity
F0T65_RS03905	COG1136	(ABC) transporter
F0T65_RS03910	COG0577	efflux transmembrane transporter activity
F0T65_RS03910	COG1136	(ABC) transporter
F0T65_RS03925	COG2322	membrane
F0T65_RS03930	COG1999	signal sequence binding
F0T65_RS03945	COG1845	cytochrome c oxidase, subunit III
F0T65_RS03950	COG1845	cytochrome c oxidase, subunit III
F0T65_RS03955	COG0109	protoheme IX farnesyltransferase activity
F0T65_RS03965	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
F0T65_RS03975	COG0509	glycine decarboxylation via glycine cleavage system
F0T65_RS03985	COG0632	four-way junction helicase activity
F0T65_RS03995	COG0517	IMP dehydrogenase activity
F0T65_RS04015	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F0T65_RS04025	COG2255	four-way junction helicase activity
F0T65_RS04030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F0T65_RS04035	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F0T65_RS04060	COG0437	4 iron, 4 sulfur cluster binding
F0T65_RS04075	COG0671	phosphoesterase, PA-phosphatase related
F0T65_RS04080	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
F0T65_RS04085	COG2251	uridine kinase activity
F0T65_RS04085	COG0195	Participates in both transcription termination and antitermination
F0T65_RS04090	COG0779	Required for maturation of 30S ribosomal subunits
F0T65_RS04130	COG3118	belongs to the thioredoxin family
F0T65_RS04145	COG3850	Histidine kinase
F0T65_RS04145	COG5002	protein histidine kinase activity
F0T65_RS04150	COG0745	RESPONSE REGULATOR receiver
F0T65_RS04160	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F0T65_RS04160	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F0T65_RS04185	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
F0T65_RS04190	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F0T65_RS04195	COG0052	Belongs to the universal ribosomal protein uS2 family
F0T65_RS04200	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
F0T65_RS04205	COG0339	signal peptide processing
F0T65_RS04210	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
F0T65_RS04220	COG0519	Catalyzes the synthesis of GMP from XMP
F0T65_RS04240	COG0351	phosphomethylpyrimidine kinase
F0T65_RS04245	COG0352	thiamine-phosphate diphosphorylase activity
F0T65_RS04250	COG2022	thiamine diphosphate biosynthetic process
F0T65_RS04260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F0T65_RS04270	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
F0T65_RS04280	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F0T65_RS04295	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F0T65_RS04325	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
F0T65_RS04330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F0T65_RS04350	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
F0T65_RS04355	COG1752	Esterase of the alpha-beta hydrolase superfamily
F0T65_RS04370	COG3177	Filamentation induced by cAMP protein fic
F0T65_RS04380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F0T65_RS04420	COG1472	Belongs to the glycosyl hydrolase 3 family
F0T65_RS04465	COG1629	transport
F0T65_RS04480	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F0T65_RS04485	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F0T65_RS04500	COG0295	cytidine deaminase activity
F0T65_RS04505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F0T65_RS04550	COG0211	Belongs to the bacterial ribosomal protein bL27 family
F0T65_RS04555	COG0261	This protein binds to 23S rRNA in the presence of protein L20
F0T65_RS04565	COG0612	Peptidase, M16
F0T65_RS04595	COG1194	a g-specific adenine glycosylase
F0T65_RS04600	COG0776	regulation of translation
F0T65_RS04615	COG4953	penicillin-binding protein 1C
F0T65_RS04625	COG0590	tRNA wobble adenosine to inosine editing
F0T65_RS04630	COG3177	Filamentation induced by cAMP protein fic
F0T65_RS04640	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
F0T65_RS04650	COG0232	Belongs to the dGTPase family. Type 2 subfamily
F0T65_RS04660	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
F0T65_RS04685	COG1301	dicarboxylic acid transport
F0T65_RS04695	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
F0T65_RS04705	COG4804	nuclease activity
F0T65_RS04710	COG0646	methionine synthase
F0T65_RS04710	COG1410	methionine synthase
F0T65_RS04715	COG0492	ferredoxin-NADP+ reductase activity
F0T65_RS04725	COG1648	precorrin-2 dehydrogenase activity
F0T65_RS04725	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F0T65_RS04730	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F0T65_RS04740	COG0175	sulfate reduction
F0T65_RS04750	COG0730	response to heat
F0T65_RS04755	COG0730	response to heat
F0T65_RS04760	COG1959	2 iron, 2 sulfur cluster binding
F0T65_RS04780	COG1765	OsmC-like protein
F0T65_RS04790	COG0527	aspartate kinase activity
F0T65_RS04790	COG0460	homoserine dehydrogenase
F0T65_RS04795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F0T65_RS04805	COG0460	homoserine dehydrogenase
F0T65_RS04805	COG0527	aspartate kinase activity
F0T65_RS04825	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
F0T65_RS04850	COG1428	Deoxynucleoside kinase
F0T65_RS04865	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
F0T65_RS04870	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F0T65_RS04875	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
F0T65_RS04885	COG0022	dehydrogenase e1 component
F0T65_RS04885	COG0508	dehydrogenase complex catalyzes the overall conversion of
F0T65_RS04890	COG2086	electron transfer activity
F0T65_RS04895	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
F0T65_RS04905	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
F0T65_RS04920	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
F0T65_RS04925	COG2226	methyltransferase
F0T65_RS04970	COG0138	bifunctional purine biosynthesis protein purh
F0T65_RS04990	COG0768	penicillin binding
F0T65_RS04995	COG0772	Belongs to the SEDS family
F0T65_RS05045	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
F0T65_RS05050	COG1185	polyribonucleotide nucleotidyltransferase activity
F0T65_RS05110	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F0T65_RS05115	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F0T65_RS05135	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
F0T65_RS05145	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F0T65_RS05150	COG0791	NLP P60 protein
F0T65_RS05155	COG0658	competence protein
F0T65_RS05155	COG2333	competence protein COMEC
F0T65_RS05170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0T65_RS05175	COG3104	oligopeptide transport
F0T65_RS05185	COG0823	Involved in the tonB-independent uptake of proteins
F0T65_RS05185	COG1506	peptidase
F0T65_RS05205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0T65_RS05210	COG1253	flavin adenine dinucleotide binding
F0T65_RS05230	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
F0T65_RS05250	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
F0T65_RS05265	COG4206	TonB-dependent receptor
F0T65_RS05265	COG1629	transport
F0T65_RS05275	COG2190	(PTS) system
F0T65_RS05275	COG2211	Major facilitator Superfamily
F0T65_RS05280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F0T65_RS05285	COG1554	hydrolase, family 65, central catalytic
F0T65_RS05290	COG1082	Xylose isomerase domain protein TIM barrel
F0T65_RS05295	COG0366	Alpha amylase catalytic
F0T65_RS05300	COG0366	Alpha amylase catalytic
F0T65_RS05305	COG0584	glycerophosphoryl diester phosphodiesterase
F0T65_RS05310	COG2081	HI0933 family
F0T65_RS05315	COG0546	phosphoglycolate phosphatase activity
F0T65_RS05345	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
F0T65_RS05380	COG1187	pseudouridine synthase activity
F0T65_RS05415	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
F0T65_RS05425	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F0T65_RS05450	COG2315	Protein conserved in bacteria
F0T65_RS05475	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
F0T65_RS05480	COG2363	Small membrane protein
F0T65_RS05555	COG4977	sequence-specific DNA binding
F0T65_RS05555	COG1917	Cupin 2, conserved barrel domain protein
F0T65_RS05595	COG4206	TonB-dependent receptor
F0T65_RS05640	COG0004	ammonium transporteR
F0T65_RS05645	COG0220	tRNA (guanine-N7-)-methyltransferase activity
F0T65_RS05665	COG2204	response regulator
F0T65_RS05675	COG0577	efflux transmembrane transporter activity
F0T65_RS05675	COG1136	(ABC) transporter
F0T65_RS05690	COG0489	protein tyrosine kinase activity
F0T65_RS05715	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F0T65_RS05720	COG1970	mechanosensitive ion channel activity
F0T65_RS05725	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F0T65_RS05745	COG4771	TonB-dependent receptor
F0T65_RS05750	COG1505	serine-type exopeptidase activity
F0T65_RS05755	COG0673	inositol 2-dehydrogenase activity
F0T65_RS05770	COG0300	oxidoreductase activity
F0T65_RS05775	COG4977	sequence-specific DNA binding
F0T65_RS05775	COG1917	Cupin 2, conserved barrel domain protein
F0T65_RS05780	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
F0T65_RS05785	COG0066	3-isopropylmalate dehydratase activity
F0T65_RS05810	COG0228	four-way junction DNA binding
F0T65_RS05815	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
F0T65_RS05825	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
F0T65_RS05885	COG1960	acyl-CoA dehydrogenase activity
F0T65_RS05910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F0T65_RS05965	COG0583	DNA-binding transcription factor activity
F0T65_RS05975	COG0252	asparaginase activity
F0T65_RS05985	COG0084	hydrolase, TatD family'
F0T65_RS06080	COG0567	Dehydrogenase, E1 component
F0T65_RS06090	COG4771	TonB-dependent receptor
F0T65_RS06120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0T65_RS06125	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
F0T65_RS06130	COG1278	Cold shock
F0T65_RS06135	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0T65_RS06140	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0T65_RS06145	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0T65_RS06150	COG0649	NAD binding
F0T65_RS06155	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
F0T65_RS06165	COG1034	ATP synthesis coupled electron transport
F0T65_RS06170	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
F0T65_RS06175	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0T65_RS06180	COG0839	Belongs to the complex I subunit 6 family
F0T65_RS06185	COG0713	ATP synthesis coupled electron transport
F0T65_RS06190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F0T65_RS06195	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0T65_RS06200	COG1007	ATP synthesis coupled electron transport
F0T65_RS06215	COG1012	belongs to the aldehyde dehydrogenase family
F0T65_RS06245	COG1619	proteins homologs of microcin C7 resistance protein MccF
F0T65_RS06250	COG0792	nuclease activity
F0T65_RS06265	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F0T65_RS06275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0T65_RS06315	COG1876	peptidase activity
F0T65_RS06335	COG1404	Belongs to the peptidase S8 family
F0T65_RS06360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0T65_RS06370	COG0316	Belongs to the HesB IscA family
F0T65_RS06375	COG0719	Fe-S assembly protein
F0T65_RS06380	COG0655	NAD(P)H dehydrogenase (quinone) activity
F0T65_RS06385	COG0396	ATPase activity
F0T65_RS06395	COG0719	Fe-S assembly protein
F0T65_RS06410	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F0T65_RS06420	COG2166	iron-sulfur cluster assembly
F0T65_RS06425	COG2151	metal-sulfur cluster biosynthetic enzyme
F0T65_RS06440	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F0T65_RS06465	COG0673	inositol 2-dehydrogenase activity
F0T65_RS06540	COG3119	arylsulfatase activity
F0T65_RS06550	COG3119	arylsulfatase activity
F0T65_RS06565	COG0571	ribonuclease III activity
F0T65_RS06570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F0T65_RS06575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0T65_RS06580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F0T65_RS06585	COG0328	RNA-DNA hybrid ribonuclease activity
F0T65_RS06595	COG1595	DNA-templated transcription, initiation
F0T65_RS06630	COG0193	aminoacyl-tRNA hydrolase activity
F0T65_RS06635	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
F0T65_RS06640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F0T65_RS06665	COG2160	L-arabinose isomerase activity
F0T65_RS06675	COG1069	ribulokinase activity
F0T65_RS06680	COG3940	Belongs to the glycosyl hydrolase 43 family
F0T65_RS06690	COG3507	Belongs to the glycosyl hydrolase 43 family
F0T65_RS06695	COG3507	Belongs to the glycosyl hydrolase 43 family
F0T65_RS06700	COG3507	Belongs to the glycosyl hydrolase 43 family
F0T65_RS06710	COG3507	Belongs to the glycosyl hydrolase 43 family
F0T65_RS06715	COG0702	epimerase
F0T65_RS06720	COG4771	TonB-dependent receptor
F0T65_RS06740	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
F0T65_RS06745	COG1085	galactose-1-phosphate uridylyltransferase
F0T65_RS06760	COG2207	Transcriptional regulator
F0T65_RS06765	COG2721	sulfolactate sulfo-lyase activity
F0T65_RS06770	COG1028	Short-chain dehydrogenase reductase Sdr
F0T65_RS06775	COG0179	Fumarylacetoacetate (FAA) hydrolase
F0T65_RS06805	COG1028	Short-chain dehydrogenase reductase Sdr
F0T65_RS06810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F0T65_RS06815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0T65_RS06830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F0T65_RS06860	COG1131	(ABC) transporter
F0T65_RS06865	COG0842	Transport permease protein
F0T65_RS06875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F0T65_RS06890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0T65_RS06895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F0T65_RS06930	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F0T65_RS06960	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
F0T65_RS06980	COG0534	Mate efflux family protein
F0T65_RS06990	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
F0T65_RS06995	COG0517	IMP dehydrogenase activity
F0T65_RS07000	COG1629	transport
F0T65_RS07005	COG0702	epimerase
F0T65_RS07025	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F0T65_RS07030	COG0756	dUTP diphosphatase activity
F0T65_RS07045	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
F0T65_RS07050	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
F0T65_RS07055	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
F0T65_RS07060	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
F0T65_RS07065	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
F0T65_RS07070	COG0356	it plays a direct role in the translocation of protons across the membrane
F0T65_RS07095	COG4152	abc transporter atp-binding protein
F0T65_RS07120	COG0859	PFAM glycosyl transferase family 9
F0T65_RS07130	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
F0T65_RS07145	COG0151	Belongs to the GarS family
F0T65_RS07165	COG1215	transferase activity, transferring glycosyl groups
F0T65_RS07170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F0T65_RS07225	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F0T65_RS07245	COG0698	ribose 5-phosphate isomerase
F0T65_RS07255	COG0557	exoribonuclease II activity
F0T65_RS07290	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F0T65_RS07325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F0T65_RS07325	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
F0T65_RS07335	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
F0T65_RS07340	COG0445	tRNA wobble uridine modification
F0T65_RS07345	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F0T65_RS07355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F0T65_RS07375	COG0758	DNA mediated transformation
F0T65_RS07380	COG0180	Tryptophanyl-tRNA synthetase
F0T65_RS07390	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
F0T65_RS07395	COG1607	acyl-coa hydrolase
F0T65_RS07405	COG0470	DNA polymerase III
F0T65_RS07445	COG0126	phosphoglycerate kinase activity
F0T65_RS07450	COG1705	Flagellar rod assembly protein muramidase FlgJ
F0T65_RS07450	COG1388	LysM domain
F0T65_RS07475	COG2885	chlorophyll binding
F0T65_RS07480	COG0793	Belongs to the peptidase S41A family
F0T65_RS07490	COG0594	ribonuclease P activity
F0T65_RS07505	COG1418	mRNA catabolic process
F0T65_RS07510	COG2267	carboxylic ester hydrolase activity
F0T65_RS07530	COG1999	signal sequence binding
F0T65_RS07535	COG3590	peptidase
F0T65_RS07545	COG0113	porphobilinogen synthase activity
F0T65_RS07560	COG3588	fructose-bisphosphate aldolase
F0T65_RS07570	COG0408	coproporphyrinogen oxidase activity
F0T65_RS07590	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
F0T65_RS07600	COG0181	hydroxymethylbilane synthase activity
F0T65_RS07610	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
F0T65_RS07625	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
F0T65_RS07635	COG1981	membrane
F0T65_RS07640	COG5000	phosphorelay sensor kinase activity
F0T65_RS07645	COG1024	Enoyl-CoA hydratase
F0T65_RS07660	COG1914	H( )-stimulated, divalent metal cation uptake system
F0T65_RS07680	COG4771	TonB-dependent receptor
F0T65_RS07715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0T65_RS07720	COG2326	polyphosphate kinase activity
F0T65_RS07740	COG0826	peptidase U32
F0T65_RS07765	COG1774	PSP1 C-terminal conserved region
F0T65_RS07775	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F0T65_RS07780	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F0T65_RS07815	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F0T65_RS07820	COG4566	intracellular signal transduction
F0T65_RS07840	COG0700	Nucleoside recognition
F0T65_RS07870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0T65_RS07880	COG0583	DNA-binding transcription factor activity
F0T65_RS07910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F0T65_RS07910	COG3153	acetyltransferase
F0T65_RS07915	COG0629	single-stranded DNA binding
F0T65_RS07930	COG1528	Iron-storage protein
F0T65_RS07935	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F0T65_RS07935	COG2885	chlorophyll binding
F0T65_RS07965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0T65_RS07965	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0T65_RS07970	COG3507	Belongs to the glycosyl hydrolase 43 family
F0T65_RS07985	COG0384	phenazine biosynthesis protein PhzF
F0T65_RS08005	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
F0T65_RS08010	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
F0T65_RS08025	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F0T65_RS08030	COG2239	Acts as a magnesium transporter
F0T65_RS08035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F0T65_RS08045	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F0T65_RS08050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F0T65_RS08075	COG0708	Exodeoxyribonuclease III
F0T65_RS08085	COG0667	Aldo Keto reductase
F0T65_RS08090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F0T65_RS08095	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
F0T65_RS08105	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
F0T65_RS08110	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
F0T65_RS08115	COG0297	glycogen (starch) synthase activity
F0T65_RS08125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F0T65_RS08140	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
F0T65_RS08160	COG0156	8-amino-7-oxononanoate synthase activity
F0T65_RS08200	COG0196	riboflavin kinase activity
F0T65_RS08210	COG1040	competence protein
F0T65_RS08215	COG0423	glycine-tRNA ligase activity
F0T65_RS08220	COG2201	protein-glutamate methylesterase activity
F0T65_RS08240	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
F0T65_RS08250	COG2318	DinB family
F0T65_RS08255	COG2378	regulation of single-species biofilm formation
F0T65_RS08305	COG0481	GTPase activity
F0T65_RS08325	COG4771	TonB-dependent receptor
F0T65_RS08340	COG3250	beta-galactosidase activity
F0T65_RS08345	COG1501	Belongs to the glycosyl hydrolase 31 family
F0T65_RS08350	COG1082	Xylose isomerase domain protein TIM barrel
F0T65_RS08360	COG1472	Belongs to the glycosyl hydrolase 3 family
F0T65_RS08365	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
F0T65_RS08395	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
F0T65_RS08405	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
F0T65_RS08410	COG1979	alcohol dehydrogenase
F0T65_RS08435	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F0T65_RS08450	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
F0T65_RS08470	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
F0T65_RS08475	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
F0T65_RS08480	COG0194	GDP metabolic process
F0T65_RS08485	COG1561	YicC-like family, N-terminal region
F0T65_RS08500	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F0T65_RS08510	COG4771	TonB-dependent receptor
F0T65_RS08515	COG0166	Belongs to the GPI family
F0T65_RS08530	COG2207	Transcriptional regulator
F0T65_RS08530	COG0662	Cupin 2, conserved barrel domain protein
F0T65_RS08555	COG3185	4-Hydroxyphenylpyruvate dioxygenase
F0T65_RS08560	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
F0T65_RS08565	COG1752	Esterase of the alpha-beta hydrolase superfamily
F0T65_RS08570	COG0322	excinuclease ABC activity
F0T65_RS08585	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F0T65_RS08590	COG2304	oxidoreductase activity
F0T65_RS08610	COG2304	oxidoreductase activity
F0T65_RS08615	COG2304	oxidoreductase activity
F0T65_RS08630	COG0714	Associated with various cellular activities
F0T65_RS08635	COG4989	oxidoreductase activity
F0T65_RS08650	COG4221	oxidoreductase activity
F0T65_RS08665	COG0626	cystathionine gamma-synthase activity
F0T65_RS08685	COG1381	Involved in DNA repair and RecF pathway recombination
F0T65_RS08690	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
F0T65_RS08715	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
F0T65_RS08720	COG1074	ATP-dependent DNA helicase activity
F0T65_RS08740	COG3842	ATPase activity
F0T65_RS08755	COG2267	carboxylic ester hydrolase activity
F0T65_RS08780	COG0006	proline dipeptidase activity
F0T65_RS08790	COG1214	PFAM Peptidase M22, glycoprotease
F0T65_RS08790	COG0456	acetyltransferase
F0T65_RS08815	COG3425	synthase
F0T65_RS08825	COG1053	succinate dehydrogenase
F0T65_RS08830	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F0T65_RS08835	COG1349	DNA-binding transcription factor activity
F0T65_RS08840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F0T65_RS08865	COG0346	lactoylglutathione lyase activity
F0T65_RS08905	COG0307	riboflavin synthase, alpha
F0T65_RS08910	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F0T65_RS08920	COG0333	Belongs to the bacterial ribosomal protein bL32 family
F0T65_RS08925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F0T65_RS08930	COG0511	ligase activity, forming carbon-carbon bonds
F0T65_RS08935	COG0439	Biotin carboxylase
F0T65_RS08965	COG2204	response regulator
F0T65_RS08975	COG1506	peptidase
F0T65_RS08975	COG0823	Involved in the tonB-independent uptake of proteins
F0T65_RS09030	COG0720	synthase
F0T65_RS09035	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F0T65_RS09060	COG0596	Alpha beta hydrolase
F0T65_RS09065	COG2211	Major facilitator Superfamily
F0T65_RS09070	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
F0T65_RS09070	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F0T65_RS09085	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
F0T65_RS09095	COG1435	thymidine kinase activity
F0T65_RS09110	COG0017	Asparaginyl-tRNA synthetase
F0T65_RS09130	COG3279	Response regulator of the LytR AlgR family
F0T65_RS09135	COG0475	glutathione-regulated potassium exporter activity
F0T65_RS09145	COG0233	cytoplasmic translational termination
F0T65_RS09150	COG0528	UMP kinase activity
F0T65_RS09160	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
F0T65_RS09165	COG1968	undecaprenyl-diphosphatase activity
F0T65_RS09175	COG2177	Part of the ABC transporter FtsEX involved in
F0T65_RS09185	COG4773	Receptor
F0T65_RS09190	COG4206	TonB-dependent receptor
F0T65_RS09200	COG0495	leucyl-tRNA aminoacylation
F0T65_RS09225	COG4585	Histidine kinase
F0T65_RS09230	COG2197	response regulator
F0T65_RS09240	COG1522	sequence-specific DNA binding
F0T65_RS09260	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
F0T65_RS09270	COG1090	epimerase
F0T65_RS09275	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F0T65_RS09305	COG5002	protein histidine kinase activity
F0T65_RS09345	COG0527	aspartate kinase activity
F0T65_RS09355	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
F0T65_RS09375	COG0793	Belongs to the peptidase S41A family
F0T65_RS09400	COG2095	MarC family integral membrane protein
F0T65_RS09420	COG0077	Prephenate dehydratase
F0T65_RS09425	COG0436	Aminotransferase
F0T65_RS09430	COG0287	Prephenate dehydrogenase
F0T65_RS09435	COG2877	3-deoxy-8-phosphooctulonate synthase activity
F0T65_RS09440	COG1629	transport
F0T65_RS09445	COG1162	GTPase activity
F0T65_RS09455	COG1490	D-aminoacyl-tRNA deacylase activity
F0T65_RS09485	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
F0T65_RS09490	COG3844	kynureninase activity
F0T65_RS09520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F0T65_RS09540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0T65_RS09545	COG0433	COG0433 Predicted ATPase
F0T65_RS09560	COG0848	biopolymer transport protein
F0T65_RS09565	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
F0T65_RS09585	COG0602	queuosine metabolic process
F0T65_RS09590	COG2318	DinB family
F0T65_RS09690	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F0T65_RS09695	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
F0T65_RS09720	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F0T65_RS09725	COG0563	adenylate kinase activity
F0T65_RS09755	COG0285	dihydrofolate synthase activity
F0T65_RS09760	COG0811	peptide transport
F0T65_RS09765	COG0848	biopolymer transport protein
F0T65_RS09785	COG1960	acyl-CoA dehydrogenase activity
F0T65_RS09795	COG1028	Short-chain dehydrogenase reductase Sdr
F0T65_RS09805	COG1127	ABC transporter
F0T65_RS09810	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F0T65_RS09815	COG1215	transferase activity, transferring glycosyl groups
F0T65_RS09830	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F0T65_RS09830	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F0T65_RS09850	COG1090	epimerase
F0T65_RS09870	COG1510	regulation of RNA biosynthetic process
F0T65_RS09880	COG2949	membrane
F0T65_RS09890	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F0T65_RS09895	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F0T65_RS09910	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
F0T65_RS09915	COG0563	adenylate kinase activity
F0T65_RS09920	COG1253	flavin adenine dinucleotide binding
F0T65_RS09925	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
F0T65_RS09930	COG3591	Belongs to the peptidase S1B family
F0T65_RS09935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F0T65_RS09940	COG2003	Belongs to the UPF0758 family
F0T65_RS09945	COG1011	Hydrolase
F0T65_RS09955	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F0T65_RS09975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F0T65_RS09995	COG4206	TonB-dependent receptor
F0T65_RS09995	COG1629	transport
F0T65_RS10005	COG4771	TonB-dependent receptor
F0T65_RS10015	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
F0T65_RS10020	COG0049	tRNA binding
F0T65_RS10025	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F0T65_RS10030	COG0051	transcription antitermination factor activity, RNA binding
F0T65_RS10035	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
F0T65_RS10040	COG0088	Forms part of the polypeptide exit tunnel
F0T65_RS10045	COG0089	rRNA binding
F0T65_RS10050	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
F0T65_RS10055	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F0T65_RS10060	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
F0T65_RS10065	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
F0T65_RS10070	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
F0T65_RS10075	COG0255	Belongs to the universal ribosomal protein uL29 family
F0T65_RS10080	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
F0T65_RS10085	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
F0T65_RS10090	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
F0T65_RS10095	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
F0T65_RS10100	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
F0T65_RS10105	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
F0T65_RS10110	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
F0T65_RS10115	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
F0T65_RS10120	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
F0T65_RS10125	COG1841	ribosomal large subunit assembly
F0T65_RS10130	COG0200	Binds to the 23S rRNA
F0T65_RS10135	COG0201	protein transport
F0T65_RS10140	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
F0T65_RS10145	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F0T65_RS10150	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F0T65_RS10155	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
F0T65_RS10160	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
F0T65_RS10165	COG0202	RNA polymerase activity
F0T65_RS10170	COG0203	ribosomal protein L17
F0T65_RS10175	COG0505	Belongs to the CarA family
F0T65_RS10180	COG0148	phosphopyruvate hydratase activity
F0T65_RS10200	COG2095	MarC family integral membrane protein
F0T65_RS10210	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
F0T65_RS10220	COG3206	protein involved in exopolysaccharide biosynthesis
F0T65_RS10220	COG0489	protein tyrosine kinase activity
F0T65_RS10225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0T65_RS10230	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
F0T65_RS10240	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
F0T65_RS10245	COG0662	Cupin 2, conserved barrel domain protein
F0T65_RS10245	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
F0T65_RS10290	COG1216	Glycosyl transferase, family 2
F0T65_RS10305	COG0438	transferase activity, transferring glycosyl groups
F0T65_RS10310	COG0110	maltose O-acetyltransferase activity
F0T65_RS10320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0T65_RS10325	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
F0T65_RS10330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0T65_RS10345	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F0T65_RS10380	COG0110	maltose O-acetyltransferase activity
F0T65_RS10395	COG1215	transferase activity, transferring glycosyl groups
F0T65_RS10400	COG1216	Glycosyl transferase, family 2
F0T65_RS10420	COG0463	Glycosyl transferase, family 2
F0T65_RS10430	COG1216	Glycosyl transferase, family 2
F0T65_RS10435	COG1696	Membrane protein involved in D-alanine export
F0T65_RS10445	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
F0T65_RS10450	COG2089	acid synthase
F0T65_RS10490	COG0438	transferase activity, transferring glycosyl groups
F0T65_RS10490	COG0297	glycogen (starch) synthase activity
F0T65_RS10540	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F0T65_RS10555	COG1183	phosphatidylcholine synthase activity
F0T65_RS10565	COG1137	ATPase activity
F0T65_RS10570	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F0T65_RS10575	COG0805	protein transport
F0T65_RS10580	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F0T65_RS10580	COG0517	IMP dehydrogenase activity
F0T65_RS10585	COG0514	ATP-dependent DNA helicase (RecQ)
F0T65_RS10595	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
F0T65_RS10620	COG0006	proline dipeptidase activity
F0T65_RS10630	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F0T65_RS10635	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F0T65_RS10640	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
F0T65_RS10650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F0T65_RS10655	COG1482	cell wall glycoprotein biosynthetic process
F0T65_RS10695	COG0326	Molecular chaperone. Has ATPase activity
F0T65_RS10705	COG2885	chlorophyll binding
F0T65_RS10710	COG3842	ATPase activity
F0T65_RS10715	COG1506	peptidase
F0T65_RS10720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F0T65_RS10730	COG3142	Participates in the control of copper homeostasis
F0T65_RS10745	COG1629	transport
F0T65_RS10780	COG3942	CHAP domain
F0T65_RS10780	COG1388	LysM domain
F0T65_RS10785	COG1696	Membrane protein involved in D-alanine export
F0T65_RS10790	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F0T65_RS10795	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
F0T65_RS10800	COG0598	Magnesium transport protein CorA
F0T65_RS10825	COG1187	pseudouridine synthase activity
F0T65_RS10845	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F0T65_RS10855	COG4115	mRNA cleavage
F0T65_RS10860	COG1663	tetraacyldisaccharide 4'-kinase activity
F0T65_RS10870	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F0T65_RS10875	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F0T65_RS10880	COG0501	Belongs to the peptidase M48B family
F0T65_RS10915	COG2808	Putative FMN-binding domain
F0T65_RS10925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
F0T65_RS10945	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
F0T65_RS10955	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
F0T65_RS10965	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
F0T65_RS10995	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
F0T65_RS11005	COG1475	DNA binding
F0T65_RS11010	COG1192	Involved in chromosome partitioning
F0T65_RS11070	COG2132	Multicopper oxidase
F0T65_RS11075	COG2217	Heavy metal translocating P-type atpase
F0T65_RS11100	COG2814	Major facilitator Superfamily
F0T65_RS11105	COG4771	TonB-dependent receptor
F0T65_RS11110	COG0702	epimerase
F0T65_RS11140	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F0T65_RS11155	COG3250	beta-galactosidase activity
F0T65_RS11200	COG0589	response to stress
F0T65_RS11200	COG0475	glutathione-regulated potassium exporter activity
F0T65_RS11205	COG0456	acetyltransferase
F0T65_RS11210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0T65_RS11250	COG1678	Uncharacterized ACR, COG1678
F0T65_RS11260	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F0T65_RS11265	COG0514	ATP-dependent DNA helicase (RecQ)
F0T65_RS11295	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F0T65_RS11300	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F0T65_RS11305	COG4771	TonB-dependent receptor
F0T65_RS11310	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
F0T65_RS11335	COG4974	Belongs to the 'phage' integrase family
F0T65_RS11345	COG1418	mRNA catabolic process
F0T65_RS11360	COG0739	heme binding
F0T65_RS11405	COG1132	(ABC) transporter
F0T65_RS11410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F0T65_RS11415	COG0463	Glycosyl transferase, family 2
F0T65_RS11425	COG0254	rRNA binding
F0T65_RS11440	COG0488	(ABC) transporter
F0T65_RS11450	COG0471	metal ion transport
F0T65_RS11470	COG0230	Belongs to the bacterial ribosomal protein bL34 family
F0T65_RS11475	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F0T65_RS11480	COG4682	membrane
F0T65_RS11505	COG0793	Belongs to the peptidase S41A family
F0T65_RS11515	COG4206	TonB-dependent receptor
F0T65_RS11525	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
F0T65_RS11530	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
F0T65_RS11535	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
F0T65_RS11550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0T65_RS11555	COG1120	ATPase activity
F0T65_RS11570	COG1187	pseudouridine synthase activity
F0T65_RS11585	COG1028	Short-chain dehydrogenase reductase Sdr
F0T65_RS11615	COG1607	acyl-coa hydrolase
F0T65_RS11635	COG1090	epimerase
F0T65_RS11645	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F0T65_RS11650	COG0415	Belongs to the DNA photolyase family
F0T65_RS11715	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F0T65_RS11720	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
F0T65_RS11735	COG3958	Transketolase
F0T65_RS11740	COG3959	Transketolase, thiamine diphosphate binding domain
F0T65_RS11765	COG0343	queuine tRNA-ribosyltransferase activity
F0T65_RS11800	COG4585	Histidine kinase
F0T65_RS11805	COG2197	response regulator
F0T65_RS11835	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F0T65_RS11845	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
F0T65_RS11850	COG0291	Belongs to the bacterial ribosomal protein bL35 family
F0T65_RS11855	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
F0T65_RS11860	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
F0T65_RS11895	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
F0T65_RS11900	COG0686	Belongs to the AlaDH PNT family
F0T65_RS11915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F0T65_RS11920	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
F0T65_RS11930	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F0T65_RS11940	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F0T65_RS11940	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F0T65_RS11950	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F0T65_RS11950	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F0T65_RS11965	COG1028	Short-chain dehydrogenase reductase Sdr
F0T65_RS11970	COG0436	Aminotransferase
F0T65_RS11985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F0T65_RS11990	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
F0T65_RS11995	COG0824	Thioesterase
F0T65_RS12000	COG1739	Uncharacterized protein family UPF0029
F0T65_RS12005	COG1011	Hydrolase
F0T65_RS12010	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F0T65_RS12010	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F0T65_RS12020	COG2890	protein-(glutamine-N5) methyltransferase activity
F0T65_RS12030	COG0124	histidyl-tRNA synthetase
F0T65_RS12040	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F0T65_RS12045	COG0484	heat shock protein binding
F0T65_RS12050	COG4152	abc transporter atp-binding protein
F0T65_RS12060	COG2204	response regulator
F0T65_RS12065	COG0513	Belongs to the DEAD box helicase family
F0T65_RS12070	COG1073	alpha beta
F0T65_RS12080	COG0561	phosphatase activity
F0T65_RS12095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F0T65_RS12105	COG0300	oxidoreductase activity
F0T65_RS12115	COG2304	oxidoreductase activity
F0T65_RS12140	COG2326	polyphosphate kinase activity
F0T65_RS12150	COG3279	Response regulator of the LytR AlgR family
F0T65_RS12165	COG0534	Mate efflux family protein
F0T65_RS12175	COG1368	sulfuric ester hydrolase activity
F0T65_RS12180	COG1703	isobutyryl-CoA mutase activity
F0T65_RS12210	COG0450	alkyl hydroperoxide reductase
F0T65_RS12215	COG4651	solute:proton antiporter activity
F0T65_RS12215	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F0T65_RS12230	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
F0T65_RS12235	COG0529	Catalyzes the synthesis of activated sulfate
F0T65_RS12260	COG4206	TonB-dependent receptor
F0T65_RS12270	COG0653	protein targeting
F0T65_RS12285	COG1136	(ABC) transporter
F0T65_RS12305	COG0488	(ABC) transporter
F0T65_RS12325	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
F0T65_RS12330	COG2244	polysaccharide biosynthetic process
F0T65_RS12355	COG1045	serine acetyltransferase
F0T65_RS12385	COG4464	protein tyrosine phosphatase activity
F0T65_RS12410	COG0508	dehydrogenase complex catalyzes the overall conversion of
F0T65_RS12420	COG0179	Fumarylacetoacetate (FAA) hydrolase
F0T65_RS12430	COG1546	Belongs to the CinA family
F0T65_RS12430	COG1058	Belongs to the CinA family
F0T65_RS12435	COG0227	Belongs to the bacterial ribosomal protein bL28 family
F0T65_RS12440	COG0267	Belongs to the bacterial ribosomal protein bL33 family
F0T65_RS12450	COG0552	protein localization to endoplasmic reticulum
F0T65_RS12470	COG0105	UTP biosynthetic process
F0T65_RS12480	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
F0T65_RS12485	COG0477	Major facilitator Superfamily
F0T65_RS12490	COG0640	Transcriptional regulator
F0T65_RS12495	COG5658	integral membrane protein
F0T65_RS12545	COG2755	lipolytic protein G-D-S-L family
F0T65_RS12565	COG0667	Aldo Keto reductase
F0T65_RS12580	COG2942	2-epimerase
F0T65_RS12585	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
F0T65_RS12590	COG2211	Major facilitator Superfamily
F0T65_RS12595	COG4124	Belongs to the glycosyl hydrolase 26 family
F0T65_RS12600	COG2169	Transcriptional regulator
F0T65_RS12605	COG4771	TonB-dependent receptor
F0T65_RS12610	COG0561	phosphatase activity
F0T65_RS12620	COG3345	alpha-galactosidase
F0T65_RS12645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F0T65_RS12660	COG0442	prolyl-tRNA aminoacylation
F0T65_RS12675	COG0268	Binds directly to 16S ribosomal RNA
F0T65_RS12680	COG2201	protein-glutamate methylesterase activity
F0T65_RS12685	COG3850	Histidine kinase
F0T65_RS12685	COG5002	protein histidine kinase activity
F0T65_RS12690	COG1217	gtp-binding protein TYPA
F0T65_RS12705	COG1131	(ABC) transporter
F0T65_RS12735	COG1028	Short-chain dehydrogenase reductase Sdr
F0T65_RS12740	COG1309	transcriptional regulator
F0T65_RS12765	COG0038	chloride channel
F0T65_RS12770	COG0346	lactoylglutathione lyase activity
F0T65_RS12775	COG0110	maltose O-acetyltransferase activity
F0T65_RS12810	COG3275	phosphorelay sensor kinase activity
F0T65_RS12835	COG3279	Response regulator of the LytR AlgR family
F0T65_RS12840	COG1612	heme a metabolic process
F0T65_RS12845	COG0517	IMP dehydrogenase activity
F0T65_RS12845	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
F0T65_RS12845	COG0617	tRNA 3'-terminal CCA addition
F0T65_RS12855	COG3022	response to hydroperoxide
F0T65_RS12875	COG1309	transcriptional regulator
F0T65_RS12885	COG0159	tryptophan synthase activity
F0T65_RS12900	COG0133	tryptophan synthase activity
F0T65_RS12905	COG0135	phosphoribosylanthranilate isomerase activity
F0T65_RS12910	COG0134	indole-3-glycerol-phosphate synthase activity
F0T65_RS12915	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F0T65_RS12925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F0T65_RS12925	COG0512	Glutamine amidotransferase of anthranilate synthase
F0T65_RS12935	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F0T65_RS12950	COG0778	Nitroreductase
F0T65_RS12960	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F0T65_RS12980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0T65_RS12980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F0T65_RS12990	COG1271	oxidase subunit
F0T65_RS12995	COG1294	oxidase, subunit
F0T65_RS13010	COG1395	domain, Protein
F0T65_RS13095	COG1349	DNA-binding transcription factor activity
F0T65_RS13120	COG2723	6-phospho-beta-galactosidase activity
F0T65_RS13170	COG4251	negative regulation of phosphorylation
F0T65_RS13175	COG0784	Response regulator, receiver
F0T65_RS13180	COG1215	transferase activity, transferring glycosyl groups
F0T65_RS13185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F0T65_RS13190	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F0T65_RS13240	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F0T65_RS13260	COG2011	ABC-type metal ion transport system permease component
F0T65_RS13280	COG1472	Belongs to the glycosyl hydrolase 3 family
F0T65_RS13290	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
F0T65_RS13295	COG3876	Protein conserved in bacteria
F0T65_RS13305	COG4771	TonB-dependent receptor
F0T65_RS13310	COG1349	DNA-binding transcription factor activity
F0T65_RS13315	COG0277	FAD linked oxidase domain protein
F0T65_RS13315	COG0247	lactate metabolic process
F0T65_RS13320	COG2382	esterase
F0T65_RS13320	COG3693	PFAM glycoside hydrolase, family 10
F0T65_RS13330	COG1649	PFAM Uncharacterised BCR, COG1649
F0T65_RS13340	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F0T65_RS13345	COG4206	TonB-dependent receptor
F0T65_RS13355	COG4251	negative regulation of phosphorylation
F0T65_RS13360	COG0784	Response regulator, receiver
F0T65_RS13360	COG2198	Histidine kinase
F0T65_RS13360	COG0643	Histidine kinase
F0T65_RS13365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0T65_RS13400	COG0628	permease
F0T65_RS13410	COG2814	Major facilitator Superfamily
F0T65_RS13440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F0T65_RS13465	COG1393	Belongs to the ArsC family
F0T65_RS13480	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F0T65_RS13480	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F0T65_RS13485	COG3158	transport of potassium into the cell
F0T65_RS13510	COG1595	DNA-templated transcription, initiation
F0T65_RS13530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F0T65_RS13545	COG0583	DNA-binding transcription factor activity
F0T65_RS13565	COG0288	reversible hydration of carbon dioxide
F0T65_RS13605	COG1960	acyl-CoA dehydrogenase activity
F0T65_RS13615	COG0183	Belongs to the thiolase family
F0T65_RS13620	COG1024	Enoyl-CoA hydratase
F0T65_RS13620	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0T65_RS13645	COG1690	Belongs to the RtcB family
F0T65_RS13655	COG0326	Molecular chaperone. Has ATPase activity
F0T65_RS13730	COG2356	endonuclease I
F0T65_RS13750	COG1169	isochorismate synthase
F0T65_RS13755	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
F0T65_RS13765	COG2321	neutral zinc metallopeptidase
F0T65_RS13770	COG0784	Response regulator, receiver
F0T65_RS13770	COG2205	protein histidine kinase activity
F0T65_RS13780	COG1012	belongs to the aldehyde dehydrogenase family
F0T65_RS13785	COG0564	pseudouridine synthase activity
F0T65_RS13795	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
F0T65_RS13805	COG1760	l-serine dehydratase
F0T65_RS13810	COG0475	glutathione-regulated potassium exporter activity
F0T65_RS13810	COG0589	response to stress
F0T65_RS13825	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F0T65_RS13825	COG2755	lipolytic protein G-D-S-L family
F0T65_RS13835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0T65_RS13865	COG2706	6-phosphogluconolactonase activity
F0T65_RS13910	COG3655	Transcriptional regulator
F0T65_RS13950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F0T65_RS13970	COG1629	transport
F0T65_RS13970	COG4206	TonB-dependent receptor
F0T65_RS13980	COG3275	phosphorelay sensor kinase activity
F0T65_RS13985	COG1132	(ABC) transporter
F0T65_RS14025	COG2234	aminopeptidase activity
F0T65_RS14040	COG1522	sequence-specific DNA binding
F0T65_RS14045	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F0T65_RS14055	COG2855	membrane
F0T65_RS14060	COG3119	arylsulfatase activity
F0T65_RS14065	COG0492	ferredoxin-NADP+ reductase activity
F0T65_RS14065	COG3118	belongs to the thioredoxin family
F0T65_RS14080	COG0702	epimerase
F0T65_RS14085	COG4771	TonB-dependent receptor
F0T65_RS14110	COG0243	molybdopterin cofactor binding
F0T65_RS14115	COG0437	4 iron, 4 sulfur cluster binding
F0T65_RS14130	COG0303	'Molybdopterin
F0T65_RS14140	COG0746	molybdenum cofactor guanylyltransferase activity
F0T65_RS14155	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F0T65_RS14165	COG0315	cyclic pyranopterin monophosphate synthase activity
F0T65_RS14165	COG0521	Mo-molybdopterin cofactor biosynthetic process
F0T65_RS14185	COG0243	molybdopterin cofactor binding
F0T65_RS14250	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F0T65_RS14270	COG0583	DNA-binding transcription factor activity
F0T65_RS14275	COG4106	trans-aconitate 2-methyltransferase activity
F0T65_RS14295	COG2249	NAD(P)H dehydrogenase (quinone) activity
F0T65_RS14300	COG0667	Aldo Keto reductase
F0T65_RS14310	COG0791	NLP P60 protein
F0T65_RS14315	COG0183	Belongs to the thiolase family
F0T65_RS14405	COG0628	permease
F0T65_RS14425	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F0T65_RS14430	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
F0T65_RS14440	COG0205	6-phosphofructokinase activity
F0T65_RS14460	COG0251	oxidation-reduction process
F0T65_RS14470	COG0860	N-Acetylmuramoyl-L-alanine amidase
F0T65_RS14470	COG1388	LysM domain
F0T65_RS14480	COG2181	nitrate reductase activity
F0T65_RS14480	COG0247	lactate metabolic process
F0T65_RS14485	COG2181	nitrate reductase activity
F0T65_RS14485	COG0247	lactate metabolic process
F0T65_RS14495	COG1335	isochorismatase
F0T65_RS14505	COG0438	transferase activity, transferring glycosyl groups
F0T65_RS14525	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
F0T65_RS14530	COG1301	dicarboxylic acid transport
F0T65_RS14535	COG0784	Response regulator, receiver
F0T65_RS14535	COG2198	Histidine kinase
F0T65_RS14535	COG5002	protein histidine kinase activity
F0T65_RS14540	COG0513	Belongs to the DEAD box helicase family
F0T65_RS14545	COG0010	Belongs to the arginase family
F0T65_RS14555	COG1228	amidohydrolase
F0T65_RS14570	COG0300	oxidoreductase activity
F0T65_RS14575	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F0T65_RS14590	COG3279	Response regulator of the LytR AlgR family
F0T65_RS14595	COG3275	phosphorelay sensor kinase activity
F0T65_RS14600	COG1629	transport
F0T65_RS14610	COG0363	glucosamine-6-phosphate deaminase activity
F0T65_RS14615	COG3525	Glycosyl hydrolase, family 20, catalytic domain
F0T65_RS14620	COG3325	Belongs to the glycosyl hydrolase 18 family
F0T65_RS14620	COG3469	chitinase activity
F0T65_RS14635	COG0488	(ABC) transporter
F0T65_RS14645	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
F0T65_RS14650	COG0540	Belongs to the ATCase OTCase family
F0T65_RS14660	COG1234	tRNA 3'-trailer cleavage
F0T65_RS14665	COG0259	pyridoxamine-phosphate oxidase activity
F0T65_RS14675	COG2885	chlorophyll binding
F0T65_RS14695	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
F0T65_RS14700	COG0248	Ppx GppA phosphatase
F0T65_RS14725	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F0T65_RS14760	COG1301	dicarboxylic acid transport
F0T65_RS14800	COG3384	dioxygenase
F0T65_RS14810	COG2226	methyltransferase
F0T65_RS14815	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
F0T65_RS14820	COG0022	dehydrogenase e1 component
F0T65_RS14830	COG1611	Belongs to the LOG family
F0T65_RS14835	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F0T65_RS14850	COG0405	Gamma-glutamyltransferase
F0T65_RS14860	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F0T65_RS14870	COG1560	Kdo2-lipid A biosynthetic process
F0T65_RS14885	COG5002	protein histidine kinase activity
F0T65_RS14915	COG1131	(ABC) transporter
F0T65_RS14920	COG1131	(ABC) transporter
F0T65_RS14925	COG0842	Transport permease protein
F0T65_RS14930	COG0842	Transport permease protein
F0T65_RS14930	COG1129	ABC transporter
F0T65_RS14935	COG0477	Major facilitator Superfamily
F0T65_RS14940	COG2423	ornithine cyclodeaminase activity
F0T65_RS14965	COG0484	heat shock protein binding
F0T65_RS14985	COG3012	SEC-C Motif Domain Protein
F0T65_RS15000	COG0697	spore germination
F0T65_RS15005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F0T65_RS15030	COG4206	TonB-dependent receptor
F0T65_RS15030	COG1629	transport
F0T65_RS15045	COG1082	Xylose isomerase domain protein TIM barrel
F0T65_RS15060	COG0534	Mate efflux family protein
F0T65_RS15090	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F0T65_RS15110	COG1127	ABC transporter
F0T65_RS15115	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F0T65_RS15120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F0T65_RS15170	COG1538	Outer membrane efflux protein
F0T65_RS15180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0T65_RS15245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0T65_RS15265	COG3279	Response regulator of the LytR AlgR family
F0T65_RS15275	COG1028	Short-chain dehydrogenase reductase Sdr
F0T65_RS15280	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
F0T65_RS15305	COG4771	TonB-dependent receptor
F0T65_RS15320	COG0657	acetylesterase activity
F0T65_RS15320	COG2755	lipolytic protein G-D-S-L family
F0T65_RS15325	COG2271	Major facilitator Superfamily
F0T65_RS15330	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
F0T65_RS15335	COG1028	Short-chain dehydrogenase reductase Sdr
F0T65_RS15340	COG1904	glucuronate isomerase
F0T65_RS15355	COG0246	Mannitol dehydrogenase
F0T65_RS15360	COG2721	sulfolactate sulfo-lyase activity
F0T65_RS15365	COG1609	Transcriptional regulator
F0T65_RS15375	COG4771	TonB-dependent receptor
F0T65_RS15385	COG0657	acetylesterase activity
F0T65_RS15395	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
F0T65_RS15400	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
F0T65_RS15410	COG4677	pectinesterase activity
F0T65_RS15420	COG2755	lipolytic protein G-D-S-L family
F0T65_RS15445	COG2188	Transcriptional regulator
F0T65_RS15455	COG3347	Dehydrogenase
F0T65_RS15455	COG1028	Short-chain dehydrogenase reductase Sdr
F0T65_RS15460	COG4952	isomerase
F0T65_RS15470	COG0247	lactate metabolic process
F0T65_RS15475	COG1139	Iron-sulfur cluster binding protein
F0T65_RS15480	COG1556	Lactate utilization protein
F0T65_RS15505	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
F0T65_RS15515	COG1104	cysteine desulfurase activity
F0T65_RS15520	COG2080	2 iron, 2 sulfur cluster binding
F0T65_RS15525	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
F0T65_RS15530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F0T65_RS15545	COG3250	beta-galactosidase activity
F0T65_RS15550	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
F0T65_RS15555	COG0702	epimerase
F0T65_RS15560	COG4771	TonB-dependent receptor
F0T65_RS15565	COG2205	protein histidine kinase activity
F0T65_RS15565	COG0745	RESPONSE REGULATOR receiver
F0T65_RS15565	COG3292	Two component regulator propeller
F0T65_RS15575	COG1312	Catalyzes the dehydration of D-mannonate
F0T65_RS15580	COG1028	Short-chain dehydrogenase reductase Sdr
F0T65_RS15585	COG0800	Aldolase
F0T65_RS15600	COG4677	pectinesterase activity
F0T65_RS15605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F0T65_RS15630	COG1546	Belongs to the CinA family
F0T65_RS15630	COG1058	Belongs to the CinA family
F0T65_RS15640	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
F0T65_RS15665	COG2133	pyrroloquinoline quinone binding
F0T65_RS15675	COG3279	Response regulator of the LytR AlgR family
F0T65_RS15680	COG3275	phosphorelay sensor kinase activity
F0T65_RS15685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0T65_RS15705	COG0738	Major facilitator superfamily
F0T65_RS15725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0T65_RS15740	COG0179	Fumarylacetoacetate (FAA) hydrolase
F0T65_RS15745	COG1063	alcohol dehydrogenase
F0T65_RS15785	COG2223	nitrite transmembrane transporter activity
F0T65_RS15810	COG3250	beta-galactosidase activity
F0T65_RS15820	COG3940	Belongs to the glycosyl hydrolase 43 family
F0T65_RS15850	COG1629	transport
F0T65_RS15850	COG4206	TonB-dependent receptor
F0T65_RS15855	COG0702	epimerase
F0T65_RS15900	COG3408	Glycogen debranching enzyme
F0T65_RS15920	COG3408	Glycogen debranching enzyme
F0T65_RS15950	COG3250	beta-galactosidase activity
F0T65_RS15980	COG0363	glucosamine-6-phosphate deaminase activity
F0T65_RS15985	COG3279	Response regulator of the LytR AlgR family
F0T65_RS15995	COG3537	Alpha-1,2-mannosidase
F0T65_RS16005	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
F0T65_RS16020	COG1446	asparaginase
F0T65_RS16025	COG3525	Glycosyl hydrolase, family 20, catalytic domain
F0T65_RS16045	COG1472	Belongs to the glycosyl hydrolase 3 family
F0T65_RS16050	COG4771	TonB-dependent receptor
F0T65_RS16110	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F0T65_RS16120	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F0T65_RS16130	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
F0T65_RS16140	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
F0T65_RS16150	COG4974	Belongs to the 'phage' integrase family
F0T65_RS16165	COG2003	Belongs to the UPF0758 family
F0T65_RS16215	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
F0T65_RS16220	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
F0T65_RS16225	COG3177	Filamentation induced by cAMP protein fic
F0T65_RS16280	COG1484	DNA-dependent DNA replication
F0T65_RS16285	COG3279	Response regulator of the LytR AlgR family
F0T65_RS16290	COG2972	Histidine kinase
F0T65_RS16310	COG1082	Xylose isomerase domain protein TIM barrel
F0T65_RS16320	COG1629	transport
F0T65_RS16320	COG4206	TonB-dependent receptor
F0T65_RS16325	COG0702	epimerase
F0T65_RS16350	COG0366	Alpha amylase catalytic
F0T65_RS16415	COG4251	negative regulation of phosphorylation
F0T65_RS16425	COG0071	Belongs to the small heat shock protein (HSP20) family
F0T65_RS16435	COG3177	Filamentation induced by cAMP protein fic
F0T65_RS16440	COG0745	RESPONSE REGULATOR receiver
F0T65_RS16470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0T65_RS16550	COG1506	peptidase
F0T65_RS16550	COG0823	Involved in the tonB-independent uptake of proteins
F0T65_RS16560	COG1629	transport
F0T65_RS16640	COG1595	DNA-templated transcription, initiation
F0T65_RS16675	COG2824	Alkylphosphonate utilization operon protein PhnA
F0T65_RS16685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F0T65_RS16705	COG1794	racemase activity, acting on amino acids and derivatives
F0T65_RS16715	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0T65_RS16830	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F0T65_RS16835	COG1472	Belongs to the glycosyl hydrolase 3 family
F0T65_RS16840	COG1609	Transcriptional regulator
F0T65_RS16845	COG3661	Belongs to the glycosyl hydrolase 67 family
F0T65_RS16850	COG1028	Short-chain dehydrogenase reductase Sdr
F0T65_RS16855	COG1312	Catalyzes the dehydration of D-mannonate
F0T65_RS16870	COG2211	Major facilitator Superfamily
F0T65_RS16890	COG2115	Belongs to the xylose isomerase family
F0T65_RS16895	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F0T65_RS16900	COG1629	transport
F0T65_RS16905	COG0702	epimerase
F0T65_RS16920	COG2382	esterase
F0T65_RS16935	COG3507	Belongs to the glycosyl hydrolase 43 family
F0T65_RS16940	COG1082	Xylose isomerase domain protein TIM barrel
F0T65_RS16945	COG1501	Belongs to the glycosyl hydrolase 31 family
F0T65_RS16950	COG1501	Belongs to the glycosyl hydrolase 31 family
F0T65_RS16955	COG3507	Belongs to the glycosyl hydrolase 43 family
F0T65_RS16960	COG3507	Belongs to the glycosyl hydrolase 43 family
F0T65_RS16970	COG4771	TonB-dependent receptor
F0T65_RS16980	COG1629	transport
F0T65_RS16980	COG4206	TonB-dependent receptor
F0T65_RS16985	COG0702	epimerase
F0T65_RS17000	COG4771	TonB-dependent receptor
F0T65_RS17020	COG2382	esterase
F0T65_RS17020	COG3693	PFAM glycoside hydrolase, family 10
F0T65_RS17055	COG0561	phosphatase activity
F0T65_RS17060	COG4771	TonB-dependent receptor
F0T65_RS17065	COG3292	Two component regulator propeller
F0T65_RS17065	COG2205	protein histidine kinase activity
F0T65_RS17065	COG0745	RESPONSE REGULATOR receiver
F0T65_RS17070	COG1472	Belongs to the glycosyl hydrolase 3 family
F0T65_RS17085	COG4771	TonB-dependent receptor
F0T65_RS17090	COG0561	phosphatase activity
F0T65_RS17100	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
F0T65_RS17115	COG3250	beta-galactosidase activity
F0T65_RS17120	COG3250	beta-galactosidase activity
F0T65_RS17125	COG1082	Xylose isomerase domain protein TIM barrel
F0T65_RS17130	COG2755	lipolytic protein G-D-S-L family
F0T65_RS17130	COG0657	acetylesterase activity
F0T65_RS17135	COG4948	Mandelate Racemase Muconate Lactonizing
F0T65_RS17140	COG1472	Belongs to the glycosyl hydrolase 3 family
F0T65_RS17145	COG3507	Belongs to the glycosyl hydrolase 43 family
F0T65_RS17150	COG3250	beta-galactosidase activity
F0T65_RS17155	COG3507	Belongs to the glycosyl hydrolase 43 family
F0T65_RS17155	COG3693	PFAM glycoside hydrolase, family 10
F0T65_RS17155	COG2382	esterase
F0T65_RS17160	COG3693	PFAM glycoside hydrolase, family 10
F0T65_RS17160	COG3507	Belongs to the glycosyl hydrolase 43 family
F0T65_RS17160	COG2382	esterase
F0T65_RS17165	COG3292	Two component regulator propeller
F0T65_RS17165	COG2205	protein histidine kinase activity
F0T65_RS17165	COG0745	RESPONSE REGULATOR receiver
F0T65_RS17175	COG1874	Beta-galactosidase
F0T65_RS17180	COG1501	Belongs to the glycosyl hydrolase 31 family
F0T65_RS17190	COG1501	Belongs to the glycosyl hydrolase 31 family
F0T65_RS17240	COG2205	protein histidine kinase activity
F0T65_RS17240	COG0784	Response regulator, receiver
F0T65_RS17320	COG0076	glutamate decarboxylase activity
F0T65_RS17370	COG3279	Response regulator of the LytR AlgR family
F0T65_RS17370	COG5000	phosphorelay sensor kinase activity
F0T65_RS17380	COG0831	urea catabolic process
F0T65_RS17385	COG0832	Belongs to the urease beta subunit family
F0T65_RS17390	COG0804	urea catabolic process
F0T65_RS17400	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
F0T65_RS17405	COG0830	nickel cation binding
F0T65_RS17410	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
F0T65_RS17415	COG0829	nickel cation binding
F0T65_RS17425	COG4413	Urea transporter
F0T65_RS17450	COG1917	Cupin 2, conserved barrel domain protein
F0T65_RS17450	COG4977	sequence-specific DNA binding
F0T65_RS17455	COG0402	S-adenosylhomocysteine deaminase activity
F0T65_RS17460	COG0666	response to abiotic stimulus
F0T65_RS17480	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F0T65_RS17485	COG4977	sequence-specific DNA binding
F0T65_RS17535	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
F0T65_RS17555	COG4771	TonB-dependent receptor
F0T65_RS17575	COG4771	TonB-dependent receptor
F0T65_RS17595	COG3250	beta-galactosidase activity
F0T65_RS17610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0T65_RS17620	COG3938	Belongs to the proline racemase family
F0T65_RS17625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0T65_RS17630	COG0006	proline dipeptidase activity
F0T65_RS17640	COG4771	TonB-dependent receptor
F0T65_RS17655	COG0006	proline dipeptidase activity
F0T65_RS17680	COG0668	transmembrane transport
F0T65_RS17690	COG2197	response regulator
F0T65_RS17705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0T65_RS17715	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F0T65_RS17755	COG0438	transferase activity, transferring glycosyl groups
F0T65_RS17765	COG4771	TonB-dependent receptor
F0T65_RS17775	COG1028	Short-chain dehydrogenase reductase Sdr
F0T65_RS17780	COG1309	transcriptional regulator
F0T65_RS17795	COG2972	Histidine kinase
F0T65_RS17800	COG3279	Response regulator of the LytR AlgR family
F0T65_RS17810	COG2985	domain, Protein
F0T65_RS17835	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
F0T65_RS17840	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F0T65_RS17845	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
F0T65_RS17900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F0T65_RS17915	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F0T65_RS17940	COG1511	domain protein
F0T65_RS17940	COG3264	Mechanosensitive ion channel
F0T65_RS17950	COG1733	regulation of RNA biosynthetic process
F0T65_RS17970	COG4716	Myosin-crossreactive antigen
F0T65_RS17980	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
F0T65_RS17985	COG0592	DNA-directed DNA polymerase activity
F0T65_RS18005	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
F0T65_RS18010	COG1702	phosphate starvation-inducible protein PhoH
F0T65_RS18025	COG0561	phosphatase activity
F0T65_RS18035	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
F0T65_RS18075	COG2205	protein histidine kinase activity
F0T65_RS18080	COG0745	RESPONSE REGULATOR receiver
F0T65_RS18085	COG1363	Peptidase, m42
F0T65_RS18150	COG0297	glycogen (starch) synthase activity
F0T65_RS18155	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
F0T65_RS18160	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
F0T65_RS18175	COG2270	Major facilitator Superfamily
F0T65_RS18195	COG1595	DNA-templated transcription, initiation
F0T65_RS18200	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F0T65_RS18215	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
F0T65_RS18220	COG2211	Major facilitator Superfamily
F0T65_RS18255	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
F0T65_RS18260	COG5006	permease, DMT superfamily
F0T65_RS18280	COG4771	TonB-dependent receptor
F0T65_RS18305	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F0T65_RS18365	COG0628	permease
F0T65_RS18375	COG0424	maF-like protein
F0T65_RS18385	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
F0T65_RS18395	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F0T65_RS18395	COG1333	cytochrome c biogenesis protein
F0T65_RS18415	COG1595	DNA-templated transcription, initiation
F0T65_RS18420	COG0386	Belongs to the glutathione peroxidase family
F0T65_RS18425	COG0456	acetyltransferase
F0T65_RS18435	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
F0T65_RS18445	COG2996	Protein conserved in bacteria
F0T65_RS18455	COG1575	Belongs to the MenA family. Type 1 subfamily
F0T65_RS18460	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
F0T65_RS18480	COG2954	triphosphatase activity
F0T65_RS18485	COG0492	ferredoxin-NADP+ reductase activity
F0T65_RS18490	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
F0T65_RS18550	COG1522	sequence-specific DNA binding
F0T65_RS18555	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
F0T65_RS18565	COG0514	ATP-dependent DNA helicase (RecQ)
F0T65_RS18585	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
F0T65_RS18615	COG0681	Belongs to the peptidase S26 family
F0T65_RS18620	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
F0T65_RS18635	COG1595	DNA-templated transcription, initiation
F0T65_RS18660	COG1045	serine acetyltransferase
F0T65_RS18690	COG0640	Transcriptional regulator
F0T65_RS18700	COG0488	(ABC) transporter
F0T65_RS18735	COG0813	purine-nucleoside phosphorylase activity
F0T65_RS18760	COG0604	alcohol dehydrogenase
F0T65_RS18785	COG0668	transmembrane transport
F0T65_RS18810	COG1252	NADH dehydrogenase
F0T65_RS18820	COG2814	Major facilitator Superfamily
F0T65_RS18850	COG2176	DNA-directed DNA polymerase activity
F0T65_RS18860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F0T65_RS18865	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
F0T65_RS18870	COG0440	acetolactate synthase activity
F0T65_RS18875	COG0028	Belongs to the TPP enzyme family
F0T65_RS18880	COG0129	dihydroxy-acid dehydratase activity
F0T65_RS18890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F0T65_RS18910	COG0140	phosphoribosyl-ATP diphosphatase activity
F0T65_RS18910	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F0T65_RS18915	COG0107	imidazoleglycerol-phosphate synthase activity
F0T65_RS18920	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
F0T65_RS18930	COG0131	Imidazoleglycerol-phosphate dehydratase
F0T65_RS18935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F0T65_RS18940	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F0T65_RS18945	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
F0T65_RS18950	COG5002	protein histidine kinase activity
F0T65_RS18955	COG0745	RESPONSE REGULATOR receiver
F0T65_RS18960	COG1368	sulfuric ester hydrolase activity
F0T65_RS18975	COG2855	membrane
F0T65_RS18980	COG0583	DNA-binding transcription factor activity
F0T65_RS19000	COG1028	Short-chain dehydrogenase reductase Sdr
F0T65_RS19025	COG4771	TonB-dependent receptor
F0T65_RS19050	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F0T65_RS19060	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F0T65_RS19065	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
F0T65_RS19070	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F0T65_RS19075	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
F0T65_RS19075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F0T65_RS19080	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F0T65_RS19085	COG1078	dGTPase activity
F0T65_RS19090	COG2204	response regulator
F0T65_RS19095	COG0802	atpase or kinase
F0T65_RS19100	COG0686	Belongs to the AlaDH PNT family
F0T65_RS19110	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
F0T65_RS19115	COG1193	negative regulation of DNA recombination
F0T65_RS19125	COG3011	Protein conserved in bacteria
F0T65_RS19130	COG0488	(ABC) transporter
F0T65_RS19160	COG0009	L-threonylcarbamoyladenylate synthase
F0T65_RS19175	COG0730	response to heat
F0T65_RS19190	COG0308	aminopeptidase N
F0T65_RS19230	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F0T65_RS19235	COG0840	transmembrane signaling receptor activity
F0T65_RS19255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0T65_RS19260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0T65_RS19270	COG3781	membrane
F0T65_RS19275	COG1917	Cupin 2, conserved barrel domain protein
F0T65_RS19275	COG4977	sequence-specific DNA binding
F0T65_RS19290	COG1012	belongs to the aldehyde dehydrogenase family
F0T65_RS19315	COG4585	Histidine kinase
F0T65_RS19325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
F0T65_RS19345	COG0640	Transcriptional regulator
F0T65_RS19350	COG1247	-acetyltransferase
F0T65_RS19365	COG0798	PFAM Bile acid sodium symporter
F0T65_RS19380	COG1595	DNA-templated transcription, initiation
F0T65_RS19420	COG3119	arylsulfatase activity
F0T65_RS19425	COG3119	arylsulfatase activity
F0T65_RS19430	COG0640	Transcriptional regulator
F0T65_RS19585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F0T65_RS19610	COG1113	amino acid transport
F0T65_RS19685	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F0T65_RS19690	COG3069	C4-dicarboxylate transmembrane transporter activity
F0T65_RS19695	COG0656	L-ascorbic acid biosynthetic process
F0T65_RS19720	COG3275	phosphorelay sensor kinase activity
F0T65_RS19725	COG3279	Response regulator of the LytR AlgR family
F0T65_RS19750	COG0247	lactate metabolic process
F0T65_RS19755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F0T65_RS19765	COG3408	Glycogen debranching enzyme
F0T65_RS19765	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
F0T65_RS19770	COG0702	epimerase
F0T65_RS19775	COG1629	transport
F0T65_RS19775	COG4206	TonB-dependent receptor
F0T65_RS19780	COG1012	belongs to the aldehyde dehydrogenase family
F0T65_RS19800	COG0583	DNA-binding transcription factor activity
F0T65_RS19830	COG2885	chlorophyll binding
F0T65_RS19835	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
F0T65_RS19845	COG1733	regulation of RNA biosynthetic process
F0T65_RS19870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0T65_RS19875	COG3119	arylsulfatase activity
F0T65_RS19890	COG0252	asparaginase activity
F0T65_RS19910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0T65_RS19920	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
F0T65_RS19935	COG3604	Transcriptional regulator
F0T65_RS19985	COG4771	TonB-dependent receptor
F0T65_RS20015	COG1858	cytochrome C peroxidase
F0T65_RS20050	COG1335	isochorismatase
F0T65_RS20075	COG0783	Belongs to the Dps family
F0T65_RS20100	COG0346	lactoylglutathione lyase activity
F0T65_RS20135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F0T65_RS20155	COG3275	phosphorelay sensor kinase activity
F0T65_RS20165	COG1764	response to oxidative stress
F0T65_RS20190	COG1764	response to oxidative stress
F0T65_RS20200	COG0583	DNA-binding transcription factor activity
F0T65_RS20220	COG1028	Short-chain dehydrogenase reductase Sdr
F0T65_RS20225	COG1733	regulation of RNA biosynthetic process
F0T65_RS20235	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
F0T65_RS20240	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F0T65_RS20245	COG0363	glucosamine-6-phosphate deaminase activity
F0T65_RS20300	COG2076	Multidrug Resistance protein
F0T65_RS20305	COG2153	protein acetylation
F0T65_RS20310	COG0583	DNA-binding transcription factor activity
F0T65_RS20335	COG0577	efflux transmembrane transporter activity
F0T65_RS20335	COG1136	(ABC) transporter
F0T65_RS20350	COG3059	membrane
F0T65_RS20355	COG2207	Transcriptional regulator
F0T65_RS20355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F0T65_RS20365	COG3852	Histidine kinase
F0T65_RS20370	COG2197	response regulator
F0T65_RS20390	COG2205	protein histidine kinase activity
F0T65_RS20390	COG0784	Response regulator, receiver
F0T65_RS20395	COG0784	Response regulator, receiver
F0T65_RS20395	COG2205	protein histidine kinase activity
F0T65_RS20400	COG0702	epimerase
F0T65_RS20420	COG2070	2-Nitropropane dioxygenase
F0T65_RS20490	COG2885	chlorophyll binding
F0T65_RS20495	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F0T65_RS20520	COG0456	acetyltransferase
F0T65_RS20530	COG0730	response to heat
F0T65_RS20550	COG0183	Belongs to the thiolase family
F0T65_RS20555	COG1053	succinate dehydrogenase
F0T65_RS20560	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F0T65_RS20565	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
F0T65_RS20590	COG2217	Heavy metal translocating P-type atpase
F0T65_RS20630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
F0T65_RS20635	COG4999	Histidine kinase
F0T65_RS20635	COG2205	protein histidine kinase activity
F0T65_RS20635	COG3437	response regulator, receiver
F0T65_RS20635	COG3850	Histidine kinase
F0T65_RS20640	COG0784	Response regulator, receiver
F0T65_RS20640	COG2205	protein histidine kinase activity
F0T65_RS20645	COG4251	negative regulation of phosphorylation
F0T65_RS20660	COG0784	Response regulator, receiver
F0T65_RS20700	COG0667	Aldo Keto reductase
F0T65_RS20705	COG1064	alcohol dehydrogenase
F0T65_RS20720	COG3250	beta-galactosidase activity
F0T65_RS20730	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F0T65_RS20735	COG0640	Transcriptional regulator
F0T65_RS20740	COG1902	pentaerythritol trinitrate reductase activity
F0T65_RS20755	COG1472	Belongs to the glycosyl hydrolase 3 family
F0T65_RS20775	COG0300	oxidoreductase activity
F0T65_RS20790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0T65_RS20795	COG3781	membrane
F0T65_RS20805	COG5002	protein histidine kinase activity
F0T65_RS20810	COG0745	RESPONSE REGULATOR receiver
F0T65_RS20825	COG1027	Aspartate ammonia-lyase
F0T65_RS20840	COG0516	GMP reductase activity
F0T65_RS20850	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
F0T65_RS20865	COG2957	Belongs to the agmatine deiminase family
F0T65_RS20880	COG0815	Transfers the fatty acyl group on membrane lipoproteins
F0T65_RS20895	COG2354	Protein conserved in bacteria
F0T65_RS20900	COG0542	response to heat
F0T65_RS20925	COG0165	Argininosuccinate lyase
F0T65_RS20935	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F0T65_RS20940	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
F0T65_RS20950	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
F0T65_RS20960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F0T65_RS20965	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
F0T65_RS20970	COG0137	argininosuccinate synthase activity
F0T65_RS21000	COG4628	conserved protein (DUF2132)
F0T65_RS21010	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
F0T65_RS21025	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F0T65_RS21035	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0T65_RS21050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F0T65_RS21055	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
F0T65_RS21070	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
F0T65_RS21075	COG1690	Belongs to the RtcB family
F0T65_RS21095	COG0237	dephospho-CoA kinase activity
F0T65_RS21105	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F0T65_RS21110	COG0497	DNA recombination
F0T65_RS21135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0T65_RS21145	COG0737	Belongs to the 5'-nucleotidase family
F0T65_RS21150	COG0737	Belongs to the 5'-nucleotidase family
F0T65_RS21160	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F0T65_RS21165	COG2885	chlorophyll binding
F0T65_RS21185	COG0359	binds to the 23S rRNA
F0T65_RS21190	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
F0T65_RS21195	COG0360	Binds together with S18 to 16S ribosomal RNA
F0T65_RS21200	COG3279	Response regulator of the LytR AlgR family
F0T65_RS21205	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F0T65_RS21230	COG4335	DNA alkylation repair
F0T65_RS21240	COG1741	Belongs to the pirin family
F0T65_RS21260	COG2329	Antibiotic biosynthesis monooxygenase
F0T65_RS21265	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
F0T65_RS21280	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F0T65_RS21300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0T65_RS21305	COG0149	triose-phosphate isomerase activity
F0T65_RS21320	COG2264	protein methyltransferase activity
F0T65_RS21350	COG0789	Transcriptional regulator
F0T65_RS21365	COG2877	3-deoxy-8-phosphooctulonate synthase activity
F0T65_RS21375	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
F0T65_RS21390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F0T65_RS21420	COG0702	epimerase
F0T65_RS21425	COG4771	TonB-dependent receptor
F0T65_RS21435	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F0T65_RS21440	COG0280	phosphate acetyltransferase
F0T65_RS21440	COG0857	belongs to the CobB CobQ family
F0T65_RS21445	COG0598	Magnesium transport protein CorA
F0T65_RS21590	COG4771	TonB-dependent receptor
F0T65_RS21650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F0T65_RS21655	COG0587	DNA-directed DNA polymerase activity
F0T65_RS21685	COG1793	dna ligase
F0T65_RS21685	COG3285	dna ligase
F0T65_RS21710	COG1074	ATP-dependent DNA helicase activity
F0T65_RS21740	COG2003	Belongs to the UPF0758 family
F0T65_RS21780	COG4974	Belongs to the 'phage' integrase family
F0T65_RS21790	COG0443	Heat shock 70 kDa protein
F0T65_RS21800	COG0025	NhaP-type Na H and K H
F0T65_RS21830	COG2267	carboxylic ester hydrolase activity
F0T65_RS21850	COG1119	ATPase activity
F0T65_RS21860	COG0564	pseudouridine synthase activity
F0T65_RS21870	COG1181	Belongs to the D-alanine--D-alanine ligase family
F0T65_RS21875	COG2323	membrane
F0T65_RS21880	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
F0T65_RS21885	COG2824	Alkylphosphonate utilization operon protein PhnA
F0T65_RS21895	COG0513	Belongs to the DEAD box helicase family
F0T65_RS21910	COG1051	belongs to the nudix hydrolase family
F0T65_RS21915	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
F0T65_RS21930	COG0799	negative regulation of ribosome biogenesis
F0T65_RS21935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F0T65_RS21945	COG4589	Belongs to the CDS family
F0T65_RS21950	COG0688	phosphatidylethanolamine metabolic process
F0T65_RS21960	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F0T65_RS21965	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
F0T65_RS21970	COG1523	belongs to the glycosyl hydrolase 13 family
F0T65_RS21980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F0T65_RS21990	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F0T65_RS22005	COG1764	response to oxidative stress
F0T65_RS22020	COG0542	response to heat
F0T65_RS22025	COG0189	ligase activity
F0T65_RS22025	COG4067	protein conserved in archaea
F0T65_RS22030	COG2323	membrane
F0T65_RS22040	COG0306	phosphate transporter
F0T65_RS22050	COG2986	histidine ammonia-lyase
F0T65_RS22060	COG0083	homoserine kinase activity
F0T65_RS22065	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F0T65_RS22130	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F0T65_RS22135	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F0T65_RS22140	COG0793	Belongs to the peptidase S41A family
F0T65_RS22145	COG0217	transcriptional regulatory protein
F0T65_RS22230	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
F0T65_RS22245	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F0T65_RS22255	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F0T65_RS22275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F0T65_RS22290	COG0348	domain, Protein
F0T65_RS22305	COG3278	Belongs to the heme-copper respiratory oxidase family
F0T65_RS22325	COG3956	TIGRFAM MazG family protein
F0T65_RS22335	COG0242	peptide deformylase activity
F0T65_RS22340	COG1289	transmembrane transporter activity
F0T65_RS22345	COG0579	oxidoreductase
F0T65_RS22350	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
F0T65_RS22365	COG0840	transmembrane signaling receptor activity
F0T65_RS22400	COG1216	Glycosyl transferase, family 2
F0T65_RS22420	COG1028	Short-chain dehydrogenase reductase Sdr
F0T65_RS22425	COG4638	Rieske (2fe-2S)
F0T65_RS22430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F0T65_RS22450	COG1104	cysteine desulfurase activity
F0T65_RS22475	COG1045	serine acetyltransferase
F0T65_RS22485	COG0667	Aldo Keto reductase
F0T65_RS22495	COG2205	protein histidine kinase activity
F0T65_RS22500	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F0T65_RS22515	COG1794	racemase activity, acting on amino acids and derivatives
F0T65_RS22525	COG0116	Belongs to the methyltransferase superfamily
F0T65_RS22525	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
F0T65_RS22530	COG2226	methyltransferase
F0T65_RS22550	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
F0T65_RS22580	COG1733	regulation of RNA biosynthetic process
F0T65_RS22615	COG1858	cytochrome C peroxidase
F0T65_RS22640	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
F0T65_RS22655	COG1295	ribonuclease BN
F0T65_RS22670	COG4206	TonB-dependent receptor
F0T65_RS22670	COG1629	transport
F0T65_RS22680	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F0T65_RS22690	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
F0T65_RS22695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F0T65_RS22740	COG0513	Belongs to the DEAD box helicase family
F0T65_RS22745	COG2706	6-phosphogluconolactonase activity
F0T65_RS22755	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
F0T65_RS22780	COG1335	isochorismatase
F0T65_RS22795	COG1234	tRNA 3'-trailer cleavage
F0T65_RS22805	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F0T65_RS22810	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F0T65_RS22820	COG1595	DNA-templated transcription, initiation
F0T65_RS22825	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F0T65_RS22875	COG0156	8-amino-7-oxononanoate synthase activity
F0T65_RS22885	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F0T65_RS22890	COG1999	signal sequence binding
F0T65_RS22900	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
F0T65_RS22910	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
F0T65_RS22915	COG1959	2 iron, 2 sulfur cluster binding
F0T65_RS22925	COG0069	glutamate synthase activity
F0T65_RS22940	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
F0T65_RS22945	COG2205	protein histidine kinase activity
F0T65_RS22950	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
F0T65_RS22955	COG0513	Belongs to the DEAD box helicase family
F0T65_RS22970	COG2195	Cleaves the N-terminal amino acid of tripeptides
F0T65_RS23020	COG0482	sulfurtransferase activity
F0T65_RS23045	COG0504	CTP synthase activity
F0T65_RS23055	COG3530	Putative quorum-sensing-regulated virulence factor
F0T65_RS23060	COG0363	glucosamine-6-phosphate deaminase activity
F0T65_RS23090	COG4771	TonB-dependent receptor
F0T65_RS23095	COG0702	epimerase
F0T65_RS23105	COG3258	Cytochrome c