locus-tag	class	description
GS03_RS00020	COG1418	mRNA catabolic process
GS03_RS00025	COG0784	Response regulator, receiver
GS03_RS00025	COG0643	Histidine kinase
GS03_RS00025	COG2198	Histidine kinase
GS03_RS00030	COG4974	Belongs to the 'phage' integrase family
GS03_RS00045	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GS03_RS00070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GS03_RS00090	COG0514	ATP-dependent DNA helicase (RecQ)
GS03_RS00095	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GS03_RS00105	COG1678	Uncharacterized ACR, COG1678
GS03_RS00130	COG0124	histidyl-tRNA synthetase
GS03_RS00140	COG2890	protein-(glutamine-N5) methyltransferase activity
GS03_RS00145	COG0456	acetyltransferase
GS03_RS00150	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GS03_RS00150	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GS03_RS00160	COG1739	Uncharacterized protein family UPF0029
GS03_RS00170	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GS03_RS00180	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GS03_RS00195	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GS03_RS00205	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GS03_RS00210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GS03_RS00230	COG2755	lipolytic protein G-D-S-L family
GS03_RS00230	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GS03_RS00250	COG0714	Associated with various cellular activities
GS03_RS00255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GS03_RS00270	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GS03_RS00285	COG4251	negative regulation of phosphorylation
GS03_RS00290	COG0784	Response regulator, receiver
GS03_RS00300	COG0784	Response regulator, receiver
GS03_RS00305	COG4251	negative regulation of phosphorylation
GS03_RS00315	COG3279	Response regulator of the LytR AlgR family
GS03_RS00345	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GS03_RS00350	COG0085	RNA polymerase activity
GS03_RS00355	COG0222	ribosome binding
GS03_RS00360	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GS03_RS00365	COG0081	regulation of translation
GS03_RS00370	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GS03_RS00390	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GS03_RS00415	COG4974	Belongs to the 'phage' integrase family
GS03_RS00420	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GS03_RS00425	COG1960	acyl-CoA dehydrogenase activity
GS03_RS00470	COG0561	phosphatase activity
GS03_RS00475	COG4771	TonB-dependent receptor
GS03_RS00480	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GS03_RS00485	COG0321	lipoyl(octanoyl) transferase activity
GS03_RS00490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GS03_RS00505	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GS03_RS00510	COG1705	Flagellar rod assembly protein muramidase FlgJ
GS03_RS00510	COG1388	LysM domain
GS03_RS00515	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GS03_RS00540	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GS03_RS00550	COG0022	dehydrogenase e1 component
GS03_RS00555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GS03_RS00560	COG0508	dehydrogenase complex catalyzes the overall conversion of
GS03_RS00575	COG2030	dehydratase
GS03_RS00575	COG1012	belongs to the aldehyde dehydrogenase family
GS03_RS00580	COG0183	Belongs to the thiolase family
GS03_RS00590	COG1250	3-hydroxyacyl-CoA dehydrogenase
GS03_RS00595	COG1024	Enoyl-CoA hydratase
GS03_RS00600	COG2151	metal-sulfur cluster biosynthetic enzyme
GS03_RS00605	COG3396	Phenylacetate-CoA oxygenase
GS03_RS00610	COG3460	Phenylacetate-CoA oxygenase
GS03_RS00615	COG3396	Phenylacetate-CoA oxygenase
GS03_RS00620	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GS03_RS00630	COG2197	response regulator
GS03_RS00640	COG4585	Histidine kinase
GS03_RS00670	COG1132	(ABC) transporter
GS03_RS00680	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GS03_RS00690	COG0789	Transcriptional regulator
GS03_RS00690	COG4978	Transcriptional regulator
GS03_RS00695	COG1704	LemA family
GS03_RS00705	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GS03_RS00710	COG0473	3-isopropylmalate dehydrogenase activity
GS03_RS00715	COG0066	3-isopropylmalate dehydratase activity
GS03_RS00720	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GS03_RS00725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GS03_RS00745	COG1160	GTP binding
GS03_RS00750	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GS03_RS00780	COG0484	heat shock protein binding
GS03_RS00800	COG0488	(ABC) transporter
GS03_RS00845	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GS03_RS00880	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GS03_RS00885	COG0459	protein refolding
GS03_RS00890	COG0586	Pfam SNARE associated Golgi protein
GS03_RS00915	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GS03_RS00935	COG1956	GAF domain-containing protein
GS03_RS00940	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GS03_RS00945	COG1185	polyribonucleotide nucleotidyltransferase activity
GS03_RS00965	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GS03_RS00970	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GS03_RS00980	COG1610	YqeY-like protein
GS03_RS00985	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GS03_RS01000	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GS03_RS01005	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GS03_RS01010	COG0772	Belongs to the SEDS family
GS03_RS01015	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GS03_RS01020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GS03_RS01025	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GS03_RS01030	COG0768	penicillin binding
GS03_RS01040	COG0275	rRNA processing
GS03_RS01045	COG2001	Belongs to the MraZ family
GS03_RS01055	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GS03_RS01070	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GS03_RS01080	COG0358	DNA primase activity
GS03_RS01110	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GS03_RS01115	COG4122	O-methyltransferase activity
GS03_RS01120	COG0671	phosphoesterase, PA-phosphatase related
GS03_RS01125	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GS03_RS01135	COG3340	Belongs to the peptidase S51 family
GS03_RS01155	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GS03_RS01160	COG0427	acetyl-CoA hydrolase
GS03_RS01175	COG0612	Peptidase, M16
GS03_RS01185	COG2967	ApaG domain
GS03_RS01190	COG1012	belongs to the aldehyde dehydrogenase family
GS03_RS01200	COG0357	Ribosomal RNA small subunit methyltransferase G
GS03_RS01205	COG3239	Fatty acid desaturase
GS03_RS01210	COG0436	Aminotransferase
GS03_RS01225	COG1741	Belongs to the pirin family
GS03_RS01250	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GS03_RS01265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GS03_RS01275	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GS03_RS01275	COG1519	Transferase
GS03_RS01280	COG4717	serine-type aminopeptidase activity
GS03_RS01300	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GS03_RS01310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GS03_RS01315	COG1428	Deoxynucleoside kinase
GS03_RS01340	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GS03_RS01350	COG0544	peptidyl-prolyl cis-trans isomerase activity
GS03_RS01355	COG1950	PFAM Membrane protein of
GS03_RS01360	COG0596	Alpha beta hydrolase
GS03_RS01365	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GS03_RS01375	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GS03_RS01405	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GS03_RS01410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GS03_RS01425	COG1331	Highly conserved protein containing a thioredoxin domain
GS03_RS01435	COG0668	transmembrane transport
GS03_RS01440	COG1214	PFAM Peptidase M22, glycoprotease
GS03_RS01465	COG2322	membrane
GS03_RS01470	COG1999	signal sequence binding
GS03_RS01495	COG0109	protoheme IX farnesyltransferase activity
GS03_RS01510	COG0509	glycine decarboxylation via glycine cleavage system
GS03_RS01520	COG0632	four-way junction helicase activity
GS03_RS01525	COG0280	phosphate acetyltransferase
GS03_RS01525	COG0281	malic enzyme
GS03_RS01530	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GS03_RS01540	COG2255	four-way junction helicase activity
GS03_RS01545	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GS03_RS01550	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GS03_RS01575	COG0437	4 iron, 4 sulfur cluster binding
GS03_RS01595	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GS03_RS01600	COG0195	Participates in both transcription termination and antitermination
GS03_RS01600	COG2251	uridine kinase activity
GS03_RS01605	COG0779	Required for maturation of 30S ribosomal subunits
GS03_RS01610	COG0589	response to stress
GS03_RS01640	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GS03_RS01640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GS03_RS01645	COG0640	Transcriptional regulator
GS03_RS01650	COG5658	integral membrane protein
GS03_RS01675	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GS03_RS01700	COG2226	methyltransferase
GS03_RS01715	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GS03_RS01715	COG2755	lipolytic protein G-D-S-L family
GS03_RS01725	COG2264	protein methyltransferase activity
GS03_RS01740	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GS03_RS01745	COG0052	Belongs to the universal ribosomal protein uS2 family
GS03_RS01750	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GS03_RS01770	COG2197	response regulator
GS03_RS01775	COG0519	Catalyzes the synthesis of GMP from XMP
GS03_RS01780	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GS03_RS01790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GS03_RS01810	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GS03_RS01840	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GS03_RS01855	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GS03_RS01870	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GS03_RS01875	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GS03_RS01880	COG0612	Peptidase, M16
GS03_RS01890	COG0697	spore germination
GS03_RS01915	COG1194	a g-specific adenine glycosylase
GS03_RS01920	COG0776	regulation of translation
GS03_RS01925	COG1530	ribonuclease E activity
GS03_RS01940	COG0590	tRNA wobble adenosine to inosine editing
GS03_RS01945	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GS03_RS01950	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GS03_RS01970	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GS03_RS01970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GS03_RS01990	COG0527	aspartate kinase activity
GS03_RS02000	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GS03_RS02020	COG0793	Belongs to the peptidase S41A family
GS03_RS02035	COG2095	MarC family integral membrane protein
GS03_RS02055	COG0720	synthase
GS03_RS02060	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GS03_RS02070	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GS03_RS02070	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GS03_RS02075	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GS03_RS02080	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GS03_RS02090	COG1435	thymidine kinase activity
GS03_RS02095	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GS03_RS02100	COG1970	mechanosensitive ion channel activity
GS03_RS02105	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GS03_RS02115	COG4771	TonB-dependent receptor
GS03_RS02125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GS03_RS02140	COG0823	Involved in the tonB-independent uptake of proteins
GS03_RS02140	COG1506	peptidase
GS03_RS02145	COG0439	Biotin carboxylase
GS03_RS02150	COG0511	ligase activity, forming carbon-carbon bonds
GS03_RS02155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GS03_RS02160	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GS03_RS02170	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GS03_RS02190	COG0346	lactoylglutathione lyase activity
GS03_RS02195	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GS03_RS02220	COG0481	GTPase activity
GS03_RS02225	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GS03_RS02245	COG3850	Histidine kinase
GS03_RS02280	COG0423	glycine-tRNA ligase activity
GS03_RS02300	COG3537	Alpha-1,2-mannosidase
GS03_RS02305	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GS03_RS02310	COG1053	succinate dehydrogenase
GS03_RS02330	COG0006	proline dipeptidase activity
GS03_RS02340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GS03_RS02355	COG0156	8-amino-7-oxononanoate synthase activity
GS03_RS02360	COG1074	ATP-dependent DNA helicase activity
GS03_RS02370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GS03_RS02385	COG0328	RNA-DNA hybrid ribonuclease activity
GS03_RS02395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GS03_RS02400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GS03_RS02405	COG0571	ribonuclease III activity
GS03_RS02415	COG0469	pyruvate kinase activity
GS03_RS02425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GS03_RS02430	COG2954	triphosphatase activity
GS03_RS02435	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GS03_RS02445	COG0166	Belongs to the GPI family
GS03_RS02465	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GS03_RS02470	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GS03_RS02475	COG0531	amino acid
GS03_RS02480	COG1752	Esterase of the alpha-beta hydrolase superfamily
GS03_RS02485	COG0322	excinuclease ABC activity
GS03_RS02490	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GS03_RS02495	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GS03_RS02515	COG1381	Involved in DNA repair and RecF pathway recombination
GS03_RS02530	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GS03_RS02540	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GS03_RS02590	COG1012	belongs to the aldehyde dehydrogenase family
GS03_RS02600	COG2824	Alkylphosphonate utilization operon protein PhnA
GS03_RS02620	COG4989	oxidoreductase activity
GS03_RS02625	COG0714	Associated with various cellular activities
GS03_RS02640	COG2304	oxidoreductase activity
GS03_RS02670	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GS03_RS02685	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GS03_RS02690	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GS03_RS02695	COG0194	GDP metabolic process
GS03_RS02710	COG1393	Belongs to the ArsC family
GS03_RS02720	COG0626	cystathionine gamma-synthase activity
GS03_RS02735	COG2151	metal-sulfur cluster biosynthetic enzyme
GS03_RS02740	COG2166	iron-sulfur cluster assembly
GS03_RS02750	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GS03_RS02765	COG0719	Fe-S assembly protein
GS03_RS02770	COG0396	ATPase activity
GS03_RS02775	COG0719	Fe-S assembly protein
GS03_RS02780	COG0316	Belongs to the HesB IscA family
GS03_RS02785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GS03_RS02805	COG0594	ribonuclease P activity
GS03_RS02815	COG0793	Belongs to the peptidase S41A family
GS03_RS02825	COG2153	protein acetylation
GS03_RS02835	COG1705	Flagellar rod assembly protein muramidase FlgJ
GS03_RS02835	COG1388	LysM domain
GS03_RS02840	COG0126	phosphoglycerate kinase activity
GS03_RS02845	COG0470	DNA polymerase III
GS03_RS02855	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GS03_RS02865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GS03_RS02870	COG0445	tRNA wobble uridine modification
GS03_RS02875	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GS03_RS02885	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
GS03_RS02885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GS03_RS02915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GS03_RS02945	COG0557	exoribonuclease II activity
GS03_RS02950	COG0698	ribose 5-phosphate isomerase
GS03_RS02960	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GS03_RS02970	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GS03_RS02975	COG1388	LysM domain
GS03_RS02975	COG4942	peptidase
GS03_RS03025	COG0438	transferase activity, transferring glycosyl groups
GS03_RS03060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GS03_RS03070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GS03_RS03115	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GS03_RS03135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GS03_RS03145	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GS03_RS03170	COG0356	it plays a direct role in the translocation of protons across the membrane
GS03_RS03175	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GS03_RS03180	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GS03_RS03185	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GS03_RS03190	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GS03_RS03195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GS03_RS03210	COG0756	dUTP diphosphatase activity
GS03_RS03215	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GS03_RS03245	COG1607	acyl-coa hydrolase
GS03_RS03255	COG0758	DNA mediated transformation
GS03_RS03290	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GS03_RS03305	COG1418	mRNA catabolic process
GS03_RS03310	COG1024	Enoyl-CoA hydratase
GS03_RS03320	COG1981	membrane
GS03_RS03330	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GS03_RS03340	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GS03_RS03345	COG0181	hydroxymethylbilane synthase activity
GS03_RS03355	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GS03_RS03360	COG0408	coproporphyrinogen oxidase activity
GS03_RS03365	COG0113	porphobilinogen synthase activity
GS03_RS03390	COG0700	Nucleoside recognition
GS03_RS03410	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GS03_RS03415	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GS03_RS03425	COG1774	PSP1 C-terminal conserved region
GS03_RS03435	COG1054	Belongs to the UPF0176 family
GS03_RS03445	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GS03_RS03445	COG0140	phosphoribosyl-ATP diphosphatase activity
GS03_RS03450	COG0107	imidazoleglycerol-phosphate synthase activity
GS03_RS03455	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GS03_RS03465	COG0131	Imidazoleglycerol-phosphate dehydratase
GS03_RS03470	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GS03_RS03475	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GS03_RS03480	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GS03_RS03495	COG1914	H( )-stimulated, divalent metal cation uptake system
GS03_RS03520	COG1999	signal sequence binding
GS03_RS03525	COG3590	peptidase
GS03_RS03550	COG0629	single-stranded DNA binding
GS03_RS03570	COG1528	Iron-storage protein
GS03_RS03575	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GS03_RS03575	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GS03_RS03580	COG1619	proteins homologs of microcin C7 resistance protein MccF
GS03_RS03585	COG0792	nuclease activity
GS03_RS03595	COG0596	Alpha beta hydrolase
GS03_RS03600	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GS03_RS03610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GS03_RS03630	COG2989	Protein conserved in bacteria
GS03_RS03645	COG1085	galactose-1-phosphate uridylyltransferase
GS03_RS03650	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GS03_RS03655	COG3250	beta-galactosidase activity
GS03_RS03675	COG3590	peptidase
GS03_RS03680	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GS03_RS03685	COG1012	belongs to the aldehyde dehydrogenase family
GS03_RS03695	COG1012	belongs to the aldehyde dehydrogenase family
GS03_RS03705	COG1953	Uracil, thiamine, allantoin
GS03_RS03720	COG0493	'glutamate synthase
GS03_RS03720	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GS03_RS03735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GS03_RS03765	COG0501	Belongs to the peptidase M48B family
GS03_RS03780	COG1007	ATP synthesis coupled electron transport
GS03_RS03785	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GS03_RS03790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GS03_RS03795	COG0713	ATP synthesis coupled electron transport
GS03_RS03800	COG0839	Belongs to the complex I subunit 6 family
GS03_RS03805	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GS03_RS03810	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GS03_RS03815	COG1034	ATP synthesis coupled electron transport
GS03_RS03825	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GS03_RS03830	COG0649	NAD binding
GS03_RS03835	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GS03_RS03840	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GS03_RS03845	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GS03_RS03850	COG1278	Cold shock
GS03_RS03855	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GS03_RS03860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GS03_RS03870	COG0708	Exodeoxyribonuclease III
GS03_RS03875	COG1360	Flagellar Motor Protein
GS03_RS03880	COG0667	Aldo Keto reductase
GS03_RS03890	COG1629	transport
GS03_RS03890	COG4206	TonB-dependent receptor
GS03_RS03905	COG3275	phosphorelay sensor kinase activity
GS03_RS03915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GS03_RS03925	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GS03_RS03940	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GS03_RS03945	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GS03_RS03950	COG0297	glycogen (starch) synthase activity
GS03_RS03960	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GS03_RS03975	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GS03_RS03980	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GS03_RS03985	COG0156	8-amino-7-oxononanoate synthase activity
GS03_RS03995	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GS03_RS04000	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GS03_RS04030	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GS03_RS04040	COG0196	riboflavin kinase activity
GS03_RS04055	COG0193	aminoacyl-tRNA hydrolase activity
GS03_RS04060	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GS03_RS04065	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GS03_RS04075	COG1621	beta-fructofuranosidase activity
GS03_RS04080	COG2239	Acts as a magnesium transporter
GS03_RS04085	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GS03_RS04100	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GS03_RS04165	COG0071	Belongs to the small heat shock protein (HSP20) family
GS03_RS04210	COG0567	Dehydrogenase, E1 component
GS03_RS04220	COG0508	dehydrogenase complex catalyzes the overall conversion of
GS03_RS04225	COG2972	Histidine kinase
GS03_RS04260	COG0084	hydrolase, TatD family'
GS03_RS04270	COG0252	asparaginase activity
GS03_RS04295	COG0017	Asparaginyl-tRNA synthetase
GS03_RS04305	COG0475	glutathione-regulated potassium exporter activity
GS03_RS04320	COG0233	cytoplasmic translational termination
GS03_RS04325	COG0528	UMP kinase activity
GS03_RS04340	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GS03_RS04345	COG1968	undecaprenyl-diphosphatase activity
GS03_RS04355	COG2177	Part of the ABC transporter FtsEX involved in
GS03_RS04360	COG0495	leucyl-tRNA aminoacylation
GS03_RS04380	COG1522	sequence-specific DNA binding
GS03_RS04400	COG2363	Small membrane protein
GS03_RS04405	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GS03_RS04420	COG0463	Glycosyl transferase, family 2
GS03_RS04425	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GS03_RS04435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GS03_RS04440	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GS03_RS04470	COG0745	RESPONSE REGULATOR receiver
GS03_RS04475	COG5002	protein histidine kinase activity
GS03_RS04480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GS03_RS04485	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GS03_RS04505	COG0489	protein tyrosine kinase activity
GS03_RS04515	COG0492	ferredoxin-NADP+ reductase activity
GS03_RS04520	COG0633	Ferredoxin
GS03_RS04540	COG1960	acyl-CoA dehydrogenase activity
GS03_RS04550	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GS03_RS04555	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GS03_RS04560	COG0228	four-way junction DNA binding
GS03_RS04580	COG3250	beta-galactosidase activity
GS03_RS04585	COG3250	beta-galactosidase activity
GS03_RS04590	COG3118	belongs to the thioredoxin family
GS03_RS04620	COG1215	transferase activity, transferring glycosyl groups
GS03_RS04630	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GS03_RS04640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GS03_RS04655	COG2315	Protein conserved in bacteria
GS03_RS04700	COG1187	pseudouridine synthase activity
GS03_RS04710	COG3850	Histidine kinase
GS03_RS04710	COG5002	protein histidine kinase activity
GS03_RS04725	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GS03_RS04745	COG2081	HI0933 family
GS03_RS04750	COG0584	glycerophosphoryl diester phosphodiesterase
GS03_RS04755	COG0366	Alpha amylase catalytic
GS03_RS04760	COG1501	Belongs to the glycosyl hydrolase 31 family
GS03_RS04765	COG0366	Alpha amylase catalytic
GS03_RS04775	COG1554	hydrolase, family 65, central catalytic
GS03_RS04780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GS03_RS04785	COG2211	Major facilitator Superfamily
GS03_RS04785	COG2190	(PTS) system
GS03_RS04790	COG1609	Transcriptional regulator
GS03_RS04795	COG1629	transport
GS03_RS04795	COG4206	TonB-dependent receptor
GS03_RS04800	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GS03_RS04810	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GS03_RS04830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GS03_RS04835	COG1253	flavin adenine dinucleotide binding
GS03_RS04860	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GS03_RS04870	COG3104	oligopeptide transport
GS03_RS04875	COG3104	oligopeptide transport
GS03_RS04880	COG3104	oligopeptide transport
GS03_RS04890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GS03_RS04895	COG0658	competence protein
GS03_RS04895	COG2333	competence protein COMEC
GS03_RS04900	COG0791	NLP P60 protein
GS03_RS04910	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GS03_RS04925	COG0772	Belongs to the SEDS family
GS03_RS04930	COG0768	penicillin binding
GS03_RS04945	COG1077	Cell shape determining protein MreB Mrl
GS03_RS04950	COG0138	bifunctional purine biosynthesis protein purh
GS03_RS04960	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GS03_RS04965	COG0191	fructose-bisphosphate aldolase activity
GS03_RS04975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GS03_RS04985	COG2226	methyltransferase
GS03_RS04990	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GS03_RS05005	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GS03_RS05015	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GS03_RS05025	COG0508	dehydrogenase complex catalyzes the overall conversion of
GS03_RS05025	COG0022	dehydrogenase e1 component
GS03_RS05035	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GS03_RS05040	COG0463	Glycosyl transferase, family 2
GS03_RS05045	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GS03_RS05055	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GS03_RS05060	COG1446	asparaginase
GS03_RS05065	COG3142	Participates in the control of copper homeostasis
GS03_RS05080	COG1428	Deoxynucleoside kinase
GS03_RS05105	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GS03_RS05110	COG0626	cystathionine gamma-synthase activity
GS03_RS05125	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GS03_RS05130	COG0460	homoserine dehydrogenase
GS03_RS05130	COG0527	aspartate kinase activity
GS03_RS05135	COG0646	methionine synthase
GS03_RS05135	COG1410	methionine synthase
GS03_RS05170	COG0077	Prephenate dehydratase
GS03_RS05175	COG0436	Aminotransferase
GS03_RS05180	COG0287	Prephenate dehydrogenase
GS03_RS05185	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GS03_RS05200	COG1162	GTPase activity
GS03_RS05205	COG1490	D-aminoacyl-tRNA deacylase activity
GS03_RS05230	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GS03_RS05235	COG3844	kynureninase activity
GS03_RS05245	COG0010	Belongs to the arginase family
GS03_RS05300	COG3609	addiction module antidote protein, CC2985 family
GS03_RS05310	COG4974	Belongs to the 'phage' integrase family
GS03_RS05330	COG2366	antibiotic biosynthetic process
GS03_RS05335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GS03_RS05360	COG0433	COG0433 Predicted ATPase
GS03_RS05375	COG0848	biopolymer transport protein
GS03_RS05380	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GS03_RS05400	COG0602	queuosine metabolic process
GS03_RS05410	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GS03_RS05415	COG2318	DinB family
GS03_RS05420	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GS03_RS05440	COG3876	Protein conserved in bacteria
GS03_RS05485	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GS03_RS05490	COG0295	cytidine deaminase activity
GS03_RS05505	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GS03_RS05515	COG0175	sulfate reduction
GS03_RS05520	COG0175	sulfate reduction
GS03_RS05525	COG2895	sulfate adenylyltransferase (ATP) activity
GS03_RS05530	COG1045	serine acetyltransferase
GS03_RS05540	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GS03_RS05540	COG1648	precorrin-2 dehydrogenase activity
GS03_RS05545	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GS03_RS05555	COG4771	TonB-dependent receptor
GS03_RS05565	COG0730	response to heat
GS03_RS05570	COG1765	OsmC-like protein
GS03_RS05590	COG0811	peptide transport
GS03_RS05625	COG1960	acyl-CoA dehydrogenase activity
GS03_RS05670	COG1028	Short-chain dehydrogenase reductase Sdr
GS03_RS05695	COG1127	ABC transporter
GS03_RS05700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GS03_RS05705	COG1215	transferase activity, transferring glycosyl groups
GS03_RS05715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GS03_RS05725	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GS03_RS05725	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GS03_RS05760	COG1510	regulation of RNA biosynthetic process
GS03_RS05770	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GS03_RS05775	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GS03_RS05790	COG0563	adenylate kinase activity
GS03_RS05795	COG1253	flavin adenine dinucleotide binding
GS03_RS05800	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GS03_RS05825	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GS03_RS05835	COG3738	Protein conserved in bacteria
GS03_RS05840	COG2003	Belongs to the UPF0758 family
GS03_RS05845	COG1011	Hydrolase
GS03_RS05855	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GS03_RS05865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GS03_RS05875	COG4771	TonB-dependent receptor
GS03_RS05885	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GS03_RS05890	COG0049	tRNA binding
GS03_RS05895	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GS03_RS05900	COG0051	transcription antitermination factor activity, RNA binding
GS03_RS05905	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GS03_RS05910	COG0088	Forms part of the polypeptide exit tunnel
GS03_RS05915	COG0089	rRNA binding
GS03_RS05920	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GS03_RS05925	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GS03_RS05930	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GS03_RS05935	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GS03_RS05940	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GS03_RS05945	COG0255	Belongs to the universal ribosomal protein uL29 family
GS03_RS05950	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GS03_RS05955	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GS03_RS05960	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GS03_RS05965	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GS03_RS05970	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GS03_RS05975	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GS03_RS05980	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GS03_RS05990	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GS03_RS05995	COG1841	ribosomal large subunit assembly
GS03_RS06000	COG0200	Binds to the 23S rRNA
GS03_RS06005	COG0201	protein transport
GS03_RS06010	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GS03_RS06015	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GS03_RS06020	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GS03_RS06025	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GS03_RS06030	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GS03_RS06035	COG0202	RNA polymerase activity
GS03_RS06040	COG0203	ribosomal protein L17
GS03_RS06050	COG0505	Belongs to the CarA family
GS03_RS06060	COG0148	phosphopyruvate hydratase activity
GS03_RS06075	COG1131	(ABC) transporter
GS03_RS06080	COG0519	Catalyzes the synthesis of GMP from XMP
GS03_RS06080	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GS03_RS06095	COG3530	Putative quorum-sensing-regulated virulence factor
GS03_RS06100	COG0504	CTP synthase activity
GS03_RS06105	COG0706	membrane insertase activity
GS03_RS06110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GS03_RS06115	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GS03_RS06125	COG0482	sulfurtransferase activity
GS03_RS06130	COG1404	Belongs to the peptidase S8 family
GS03_RS06150	COG2885	chlorophyll binding
GS03_RS06155	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
GS03_RS06190	COG0019	diaminopimelate decarboxylase activity
GS03_RS06200	COG0067	glutamate synthase
GS03_RS06200	COG0070	glutamate synthase
GS03_RS06200	COG0069	glutamate synthase activity
GS03_RS06225	COG1611	Belongs to the LOG family
GS03_RS06235	COG0038	chloride channel
GS03_RS06260	COG0405	Gamma-glutamyltransferase
GS03_RS06270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GS03_RS06275	COG1473	amidohydrolase
GS03_RS06345	COG0174	glutamine synthetase
GS03_RS06370	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GS03_RS06395	COG3384	dioxygenase
GS03_RS06415	COG2264	protein methyltransferase activity
GS03_RS06425	COG0149	triose-phosphate isomerase activity
GS03_RS06450	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GS03_RS06460	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GS03_RS06480	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GS03_RS06495	COG3279	Response regulator of the LytR AlgR family
GS03_RS06500	COG3275	phosphorelay sensor kinase activity
GS03_RS06505	COG1523	belongs to the glycosyl hydrolase 13 family
GS03_RS06525	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GS03_RS06540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GS03_RS06550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GS03_RS06570	COG0110	maltose O-acetyltransferase activity
GS03_RS06575	COG2244	polysaccharide biosynthetic process
GS03_RS06590	COG0438	transferase activity, transferring glycosyl groups
GS03_RS06600	COG1216	Glycosyl transferase, family 2
GS03_RS06600	COG0463	Glycosyl transferase, family 2
GS03_RS06620	COG2884	Cell division ATP-binding protein ftsE
GS03_RS06640	COG0367	asparagine synthase
GS03_RS06645	COG0187	DNA topoisomerase II activity
GS03_RS06655	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GS03_RS06680	COG2204	response regulator
GS03_RS06695	COG3590	peptidase
GS03_RS06720	COG2095	MarC family integral membrane protein
GS03_RS06730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GS03_RS06735	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GS03_RS06745	COG0489	protein tyrosine kinase activity
GS03_RS06745	COG3206	protein involved in exopolysaccharide biosynthesis
GS03_RS06755	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GS03_RS06760	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GS03_RS06830	COG0438	transferase activity, transferring glycosyl groups
GS03_RS06830	COG0297	glycogen (starch) synthase activity
GS03_RS06840	COG0438	transferase activity, transferring glycosyl groups
GS03_RS06870	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GS03_RS06880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GS03_RS06885	COG1086	Polysaccharide biosynthesis protein
GS03_RS06895	COG0489	protein tyrosine kinase activity
GS03_RS06945	COG1083	cytidylyl-transferase
GS03_RS06950	COG2089	acid synthase
GS03_RS07000	COG0463	Glycosyl transferase, family 2
GS03_RS07015	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GS03_RS07040	COG0438	transferase activity, transferring glycosyl groups
GS03_RS07055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GS03_RS07075	COG1137	ATPase activity
GS03_RS07080	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GS03_RS07085	COG0805	protein transport
GS03_RS07090	COG0517	IMP dehydrogenase activity
GS03_RS07090	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GS03_RS07095	COG0514	ATP-dependent DNA helicase (RecQ)
GS03_RS07110	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GS03_RS07120	COG1595	DNA-templated transcription, initiation
GS03_RS07140	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GS03_RS07150	COG0688	phosphatidylethanolamine metabolic process
GS03_RS07155	COG4589	Belongs to the CDS family
GS03_RS07165	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GS03_RS07170	COG0799	negative regulation of ribosome biogenesis
GS03_RS07185	COG0045	succinate-CoA ligase (ADP-forming) activity
GS03_RS07195	COG0463	Glycosyl transferase, family 2
GS03_RS07205	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GS03_RS07205	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GS03_RS07210	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GS03_RS07220	COG0450	alkyl hydroperoxide reductase
GS03_RS07225	COG1482	cell wall glycoprotein biosynthetic process
GS03_RS07240	COG0590	tRNA wobble adenosine to inosine editing
GS03_RS07275	COG4266	Belongs to the allantoicase family
GS03_RS07280	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GS03_RS07285	COG3279	Response regulator of the LytR AlgR family
GS03_RS07290	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GS03_RS07290	COG3608	succinylglutamate desuccinylase aspartoacylase
GS03_RS07295	COG0303	'Molybdopterin
GS03_RS07300	COG0730	response to heat
GS03_RS07315	COG0314	molybdopterin synthase activity
GS03_RS07325	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GS03_RS07390	COG0784	Response regulator, receiver
GS03_RS07390	COG2205	protein histidine kinase activity
GS03_RS07390	COG5002	protein histidine kinase activity
GS03_RS07400	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GS03_RS07415	COG0442	prolyl-tRNA aminoacylation
GS03_RS07425	COG0268	Binds directly to 16S ribosomal RNA
GS03_RS07435	COG2202	Pas domain
GS03_RS07435	COG3920	Histidine kinase
GS03_RS07440	COG1217	gtp-binding protein TYPA
GS03_RS07445	COG3507	Belongs to the glycosyl hydrolase 43 family
GS03_RS07445	COG3693	PFAM glycoside hydrolase, family 10
GS03_RS07445	COG2382	esterase
GS03_RS07465	COG1131	(ABC) transporter
GS03_RS07505	COG3275	phosphorelay sensor kinase activity
GS03_RS07525	COG3279	Response regulator of the LytR AlgR family
GS03_RS07530	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GS03_RS07550	COG1612	heme a metabolic process
GS03_RS07555	COG0517	IMP dehydrogenase activity
GS03_RS07555	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GS03_RS07555	COG0617	tRNA 3'-terminal CCA addition
GS03_RS07570	COG1216	Glycosyl transferase, family 2
GS03_RS07585	COG0297	glycogen (starch) synthase activity
GS03_RS07590	COG2171	N-acyltransferase activity
GS03_RS07595	COG3015	lipoprotein NlpE involved in copper resistance
GS03_RS07600	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GS03_RS07605	COG0242	peptide deformylase activity
GS03_RS07615	COG3956	TIGRFAM MazG family protein
GS03_RS07620	COG0531	amino acid
GS03_RS07625	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GS03_RS07630	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GS03_RS07640	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GS03_RS07645	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GS03_RS07650	COG1187	pseudouridine synthase activity
GS03_RS07655	COG4242	Belongs to the peptidase S51 family
GS03_RS07660	COG1446	asparaginase
GS03_RS07675	COG2311	Membrane
GS03_RS07685	COG2311	Membrane
GS03_RS07720	COG0612	Peptidase, M16
GS03_RS07725	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GS03_RS07730	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GS03_RS07735	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GS03_RS07740	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GS03_RS07780	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GS03_RS07790	COG0366	Alpha amylase catalytic
GS03_RS07795	COG3281	Trehalose synthase
GS03_RS07800	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GS03_RS07815	COG2270	Major facilitator Superfamily
GS03_RS07825	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GS03_RS07835	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GS03_RS07840	COG2211	Major facilitator Superfamily
GS03_RS07850	COG1301	dicarboxylic acid transport
GS03_RS07865	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GS03_RS07870	COG1584	GPR1 FUN34 yaaH family protein
GS03_RS07890	COG3781	membrane
GS03_RS07900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GS03_RS07905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GS03_RS07910	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GS03_RS07925	COG0784	Response regulator, receiver
GS03_RS07925	COG2205	protein histidine kinase activity
GS03_RS07930	COG1476	TRANSCRIPTIONal
GS03_RS07940	COG0606	chelatase, subunit chli
GS03_RS07945	COG3425	synthase
GS03_RS07950	COG2321	neutral zinc metallopeptidase
GS03_RS07955	COG2205	protein histidine kinase activity
GS03_RS07955	COG3437	response regulator, receiver
GS03_RS07955	COG3850	Histidine kinase
GS03_RS07955	COG4999	Histidine kinase
GS03_RS07960	COG1012	belongs to the aldehyde dehydrogenase family
GS03_RS07970	COG0564	pseudouridine synthase activity
GS03_RS07980	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GS03_RS07985	COG2204	response regulator
GS03_RS08010	COG0488	(ABC) transporter
GS03_RS08020	COG2326	polyphosphate kinase activity
GS03_RS08045	COG1703	isobutyryl-CoA mutase activity
GS03_RS08055	COG0277	FAD linked oxidase domain protein
GS03_RS08085	COG0653	protein targeting
GS03_RS08095	COG2096	Adenosyltransferase
GS03_RS08105	COG1136	(ABC) transporter
GS03_RS08120	COG0488	(ABC) transporter
GS03_RS08130	COG0508	dehydrogenase complex catalyzes the overall conversion of
GS03_RS08150	COG0179	Fumarylacetoacetate (FAA) hydrolase
GS03_RS08160	COG1546	Belongs to the CinA family
GS03_RS08160	COG1058	Belongs to the CinA family
GS03_RS08165	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GS03_RS08170	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GS03_RS08180	COG0552	protein localization to endoplasmic reticulum
GS03_RS08205	COG0494	nUDIX hydrolase
GS03_RS08220	COG2267	carboxylic ester hydrolase activity
GS03_RS08235	COG2996	Protein conserved in bacteria
GS03_RS08240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GS03_RS08260	COG2808	Putative FMN-binding domain
GS03_RS08265	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GS03_RS08290	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GS03_RS08300	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GS03_RS08305	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GS03_RS08335	COG0681	Belongs to the peptidase S26 family
GS03_RS08340	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GS03_RS08350	COG1475	DNA binding
GS03_RS08355	COG1192	Involved in chromosome partitioning
GS03_RS08360	COG1028	Short-chain dehydrogenase reductase Sdr
GS03_RS08375	COG0436	Aminotransferase
GS03_RS08395	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GS03_RS08400	COG0540	Belongs to the ATCase OTCase family
GS03_RS08410	COG2356	endonuclease I
GS03_RS08420	COG3158	transport of potassium into the cell
GS03_RS08440	COG1595	DNA-templated transcription, initiation
GS03_RS08465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GS03_RS08470	COG0673	inositol 2-dehydrogenase activity
GS03_RS08475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GS03_RS08510	COG0583	DNA-binding transcription factor activity
GS03_RS08530	COG0288	reversible hydration of carbon dioxide
GS03_RS08545	COG2032	superoxide dismutase activity
GS03_RS08565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GS03_RS08575	COG3022	response to hydroperoxide
GS03_RS08585	COG2814	Major facilitator Superfamily
GS03_RS08600	COG1309	transcriptional regulator
GS03_RS08605	COG0159	tryptophan synthase activity
GS03_RS08610	COG0133	tryptophan synthase activity
GS03_RS08615	COG0135	phosphoribosylanthranilate isomerase activity
GS03_RS08620	COG0134	indole-3-glycerol-phosphate synthase activity
GS03_RS08625	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GS03_RS08635	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GS03_RS08640	COG2353	YceI-like domain
GS03_RS08645	COG0778	Nitroreductase
GS03_RS08695	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GS03_RS08705	COG0205	6-phosphofructokinase activity
GS03_RS08720	COG1803	Methylglyoxal synthase
GS03_RS08760	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GS03_RS08770	COG0025	NhaP-type Na H and K H
GS03_RS08785	COG0251	oxidation-reduction process
GS03_RS08795	COG0860	N-Acetylmuramoyl-L-alanine amidase
GS03_RS08800	COG2247	cell wall binding repeat
GS03_RS08800	COG0860	N-Acetylmuramoyl-L-alanine amidase
GS03_RS08810	COG0247	lactate metabolic process
GS03_RS08810	COG2181	nitrate reductase activity
GS03_RS08820	COG2181	nitrate reductase activity
GS03_RS08820	COG0247	lactate metabolic process
GS03_RS08825	COG0671	phosphoesterase, PA-phosphatase related
GS03_RS08835	COG1472	Belongs to the glycosyl hydrolase 3 family
GS03_RS08860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GS03_RS08870	COG1082	Xylose isomerase domain protein TIM barrel
GS03_RS08885	COG2234	aminopeptidase activity
GS03_RS08890	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GS03_RS08900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GS03_RS08905	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GS03_RS08915	COG1234	tRNA 3'-trailer cleavage
GS03_RS08940	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GS03_RS08950	COG0513	Belongs to the DEAD box helicase family
GS03_RS08990	COG0302	gtp cyclohydrolase
GS03_RS09010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GS03_RS09015	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GS03_RS09030	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GS03_RS09050	COG0012	GTP binding
GS03_RS09085	COG2132	Multicopper oxidase
GS03_RS09095	COG2226	methyltransferase
GS03_RS09110	COG0861	Integral membrane protein TerC family
GS03_RS09135	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GS03_RS09160	COG2226	methyltransferase
GS03_RS09165	COG0116	Belongs to the methyltransferase superfamily
GS03_RS09165	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GS03_RS09200	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GS03_RS09215	COG1764	response to oxidative stress
GS03_RS09225	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GS03_RS09250	COG2195	Cleaves the N-terminal amino acid of tripeptides
GS03_RS09270	COG4774	siderophore transport
GS03_RS09285	COG0038	chloride channel
GS03_RS09290	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GS03_RS09305	COG4251	negative regulation of phosphorylation
GS03_RS09310	COG0784	Response regulator, receiver
GS03_RS09320	COG0284	orotidine-5'-phosphate decarboxylase activity
GS03_RS09325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GS03_RS09335	COG0788	formyltetrahydrofolate deformylase activity
GS03_RS09340	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GS03_RS09340	COG1703	isobutyryl-CoA mutase activity
GS03_RS09340	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GS03_RS09345	COG1629	transport
GS03_RS09360	COG0156	8-amino-7-oxononanoate synthase activity
GS03_RS09365	COG2198	Histidine kinase
GS03_RS09365	COG0784	Response regulator, receiver
GS03_RS09365	COG5002	protein histidine kinase activity
GS03_RS09370	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GS03_RS09375	COG0513	Belongs to the DEAD box helicase family
GS03_RS09385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GS03_RS09395	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GS03_RS09410	COG0004	ammonium transporteR
GS03_RS09415	COG0517	IMP dehydrogenase activity
GS03_RS09415	COG0516	GMP reductase activity
GS03_RS09425	COG0167	dihydroorotate dehydrogenase activity
GS03_RS09445	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GS03_RS09450	COG3279	Response regulator of the LytR AlgR family
GS03_RS09455	COG0360	Binds together with S18 to 16S ribosomal RNA
GS03_RS09460	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GS03_RS09465	COG0359	binds to the 23S rRNA
GS03_RS09475	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GS03_RS09490	COG0737	Belongs to the 5'-nucleotidase family
GS03_RS09505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GS03_RS09530	COG0497	DNA recombination
GS03_RS09535	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GS03_RS09545	COG1216	Glycosyl transferase, family 2
GS03_RS09545	COG0463	Glycosyl transferase, family 2
GS03_RS09550	COG0237	dephospho-CoA kinase activity
GS03_RS09570	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GS03_RS09575	COG0322	excinuclease ABC activity
GS03_RS09590	COG1250	3-hydroxyacyl-CoA dehydrogenase
GS03_RS09595	COG0673	inositol 2-dehydrogenase activity
GS03_RS09600	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GS03_RS09610	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GS03_RS09620	COG4628	conserved protein (DUF2132)
GS03_RS09625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GS03_RS09660	COG0668	transmembrane transport
GS03_RS09665	COG1607	acyl-coa hydrolase
GS03_RS09690	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GS03_RS09715	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GS03_RS09720	COG2382	esterase
GS03_RS09730	COG5002	protein histidine kinase activity
GS03_RS09735	COG0745	RESPONSE REGULATOR receiver
GS03_RS09740	COG1368	sulfuric ester hydrolase activity
GS03_RS09750	COG0443	Heat shock 70 kDa protein
GS03_RS09775	COG0101	tRNA pseudouridine synthase activity
GS03_RS09780	COG1132	(ABC) transporter
GS03_RS09785	COG3647	Membrane
GS03_RS09790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GS03_RS09815	COG0183	Belongs to the thiolase family
GS03_RS09820	COG0791	NLP P60 protein
GS03_RS09825	COG0366	Alpha amylase catalytic
GS03_RS09835	COG1104	cysteine desulfurase activity
GS03_RS09845	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GS03_RS09855	COG0105	UTP biosynthetic process
GS03_RS09870	COG0525	valine-tRNA ligase activity
GS03_RS09885	COG0436	Aminotransferase
GS03_RS09895	COG0302	gtp cyclohydrolase
GS03_RS09900	COG0215	cysteine-tRNA ligase activity
GS03_RS09905	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GS03_RS09910	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GS03_RS09915	COG0564	pseudouridine synthase activity
GS03_RS09925	COG1181	Belongs to the D-alanine--D-alanine ligase family
GS03_RS09935	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GS03_RS09960	COG0513	Belongs to the DEAD box helicase family
GS03_RS09980	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GS03_RS09990	COG1368	sulfuric ester hydrolase activity
GS03_RS09995	COG1022	Amp-dependent synthetase and ligase
GS03_RS10000	COG2267	carboxylic ester hydrolase activity
GS03_RS10030	COG5002	protein histidine kinase activity
GS03_RS10030	COG2198	Histidine kinase
GS03_RS10030	COG0784	Response regulator, receiver
GS03_RS10060	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GS03_RS10065	COG1127	ABC transporter
GS03_RS10110	COG2353	YceI-like domain
GS03_RS10130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GS03_RS10135	COG1309	transcriptional regulator
GS03_RS10155	COG3422	double-strand break repair
GS03_RS10180	COG1846	Transcriptional regulator
GS03_RS10185	COG1250	3-hydroxyacyl-CoA dehydrogenase
GS03_RS10185	COG1024	Enoyl-CoA hydratase
GS03_RS10190	COG0183	Belongs to the thiolase family
GS03_RS10195	COG1960	acyl-CoA dehydrogenase activity
GS03_RS10205	COG1228	amidohydrolase
GS03_RS10215	COG1760	l-serine dehydratase
GS03_RS10225	COG3158	transport of potassium into the cell
GS03_RS10235	COG2205	protein histidine kinase activity
GS03_RS10240	COG1668	transmembrane transport
GS03_RS10245	COG4152	abc transporter atp-binding protein
GS03_RS10250	COG0484	heat shock protein binding
GS03_RS10255	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GS03_RS10260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GS03_RS10320	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GS03_RS10325	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GS03_RS10325	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GS03_RS10375	COG1704	LemA family
GS03_RS10390	COG0488	(ABC) transporter
GS03_RS10400	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GS03_RS10405	COG0300	oxidoreductase activity
GS03_RS10410	COG4948	Mandelate Racemase Muconate Lactonizing
GS03_RS10460	COG0022	dehydrogenase e1 component
GS03_RS10480	COG0813	purine-nucleoside phosphorylase activity
GS03_RS10490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GS03_RS10515	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GS03_RS10520	COG1193	negative regulation of DNA recombination
GS03_RS10525	COG3011	Protein conserved in bacteria
GS03_RS10535	COG1301	dicarboxylic acid transport
GS03_RS10540	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GS03_RS10565	COG0438	transferase activity, transferring glycosyl groups
GS03_RS10575	COG1028	Short-chain dehydrogenase reductase Sdr
GS03_RS10580	COG1595	DNA-templated transcription, initiation
GS03_RS10600	COG1858	cytochrome C peroxidase
GS03_RS10610	COG1858	cytochrome C peroxidase
GS03_RS10635	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GS03_RS10640	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GS03_RS10645	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GS03_RS10650	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GS03_RS10650	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GS03_RS10655	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GS03_RS10660	COG1078	dGTPase activity
GS03_RS10665	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GS03_RS10675	COG0154	amidase activity
GS03_RS10685	COG0386	Belongs to the glutathione peroxidase family
GS03_RS10690	COG1595	DNA-templated transcription, initiation
GS03_RS10700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GS03_RS10700	COG1333	cytochrome c biogenesis protein
GS03_RS10720	COG0424	maF-like protein
GS03_RS10765	COG1028	Short-chain dehydrogenase reductase Sdr
GS03_RS10770	COG0415	Belongs to the DNA photolyase family
GS03_RS10790	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GS03_RS10795	COG2311	Membrane
GS03_RS10815	COG2814	Major facilitator Superfamily
GS03_RS10865	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GS03_RS10880	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GS03_RS10885	COG0793	Belongs to the peptidase S41A family
GS03_RS10890	COG0217	transcriptional regulatory protein
GS03_RS10895	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GS03_RS10950	COG0306	phosphate transporter
GS03_RS10960	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GS03_RS10985	COG1393	Belongs to the ArsC family
GS03_RS11005	COG0259	pyridoxamine-phosphate oxidase activity
GS03_RS11010	COG1234	tRNA 3'-trailer cleavage
GS03_RS11035	COG0542	response to heat
GS03_RS11070	COG2986	histidine ammonia-lyase
GS03_RS11075	COG0460	homoserine dehydrogenase
GS03_RS11075	COG0527	aspartate kinase activity
GS03_RS11080	COG0083	homoserine kinase activity
GS03_RS11085	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GS03_RS11105	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GS03_RS11115	COG0542	response to heat
GS03_RS11120	COG2197	response regulator
GS03_RS11130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GS03_RS11140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GS03_RS11180	COG0179	Fumarylacetoacetate (FAA) hydrolase
GS03_RS11185	COG4106	trans-aconitate 2-methyltransferase activity
GS03_RS11190	COG3473	Maleate cis-trans isomerase
GS03_RS11210	COG0702	epimerase
GS03_RS11215	COG0415	Belongs to the DNA photolyase family
GS03_RS11220	COG3046	protein related to deoxyribodipyrimidine photolyase
GS03_RS11230	COG0415	Belongs to the DNA photolyase family
GS03_RS11250	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GS03_RS11290	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GS03_RS11295	COG1522	sequence-specific DNA binding
GS03_RS11315	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GS03_RS11325	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GS03_RS11360	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GS03_RS11370	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GS03_RS11390	COG2885	chlorophyll binding
GS03_RS11405	COG2885	chlorophyll binding
GS03_RS11410	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GS03_RS11420	COG0598	Magnesium transport protein CorA
GS03_RS11425	COG1228	amidohydrolase
GS03_RS11440	COG0513	Belongs to the DEAD box helicase family
GS03_RS11450	COG0488	(ABC) transporter
GS03_RS11460	COG2885	chlorophyll binding
GS03_RS11490	COG1064	alcohol dehydrogenase
GS03_RS11500	COG0791	NLP P60 protein
GS03_RS11525	COG0009	L-threonylcarbamoyladenylate synthase
GS03_RS11530	COG0210	DNA helicase
GS03_RS11545	COG2154	pterin-4-alpha-carbinolamine dehydratase
GS03_RS11550	COG4232	protein-disulfide reductase activity
GS03_RS11555	COG0037	tRNA processing
GS03_RS11575	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GS03_RS11580	COG0531	amino acid
GS03_RS11590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GS03_RS11600	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GS03_RS11615	COG0640	Transcriptional regulator
GS03_RS11630	COG1674	ftsk spoiiie
GS03_RS11645	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GS03_RS11645	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GS03_RS11655	COG0137	argininosuccinate synthase activity
GS03_RS11660	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GS03_RS11675	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GS03_RS11680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GS03_RS11685	COG0165	Argininosuccinate lyase
GS03_RS11715	COG0732	type I restriction modification DNA specificity domain
GS03_RS11745	COG2827	Endonuclease containing a URI domain
GS03_RS11900	COG2755	lipolytic protein G-D-S-L family
GS03_RS11910	COG4677	pectinesterase activity
GS03_RS11915	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GS03_RS11965	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GS03_RS11970	COG0702	epimerase
GS03_RS11975	COG4771	TonB-dependent receptor
GS03_RS11985	COG1609	Transcriptional regulator
GS03_RS11990	COG2721	sulfolactate sulfo-lyase activity
GS03_RS11995	COG0246	Mannitol dehydrogenase
GS03_RS12000	COG0800	Aldolase
GS03_RS12025	COG1904	glucuronate isomerase
GS03_RS12030	COG1028	Short-chain dehydrogenase reductase Sdr
GS03_RS12035	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GS03_RS12040	COG2271	Major facilitator Superfamily
GS03_RS12045	COG2755	lipolytic protein G-D-S-L family
GS03_RS12045	COG0657	acetylesterase activity
GS03_RS12090	COG2211	Major facilitator Superfamily
GS03_RS12105	COG0019	diaminopimelate decarboxylase activity
GS03_RS12150	COG2313	pseudouridylate synthase activity
GS03_RS12155	COG1105	Belongs to the carbohydrate kinase PfkB family
GS03_RS12160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GS03_RS12185	COG0348	domain, Protein
GS03_RS12200	COG3278	Belongs to the heme-copper respiratory oxidase family
GS03_RS12260	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GS03_RS12285	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GS03_RS12305	COG4452	Inner membrane protein CreD
GS03_RS12320	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GS03_RS12325	COG1575	Belongs to the MenA family. Type 1 subfamily
GS03_RS12340	COG0477	Major facilitator Superfamily
GS03_RS12345	COG3279	Response regulator of the LytR AlgR family
GS03_RS12350	COG2972	Histidine kinase
GS03_RS12355	COG2972	Histidine kinase
GS03_RS12375	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GS03_RS12390	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GS03_RS12395	COG1663	tetraacyldisaccharide 4'-kinase activity
GS03_RS12405	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GS03_RS12440	COG1028	Short-chain dehydrogenase reductase Sdr
GS03_RS12455	COG0305	Participates in initiation and elongation during chromosome replication
GS03_RS12460	COG0825	malonyl-CoA metabolic process
GS03_RS12475	COG0343	queuine tRNA-ribosyltransferase activity
GS03_RS12480	COG2201	protein-glutamate methylesterase activity
GS03_RS12485	COG3959	Transketolase, thiamine diphosphate binding domain
GS03_RS12495	COG3958	Transketolase
GS03_RS12525	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GS03_RS12530	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GS03_RS12595	COG4206	TonB-dependent receptor
GS03_RS12610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GS03_RS12615	COG1120	ATPase activity
GS03_RS12620	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GS03_RS12625	COG1187	pseudouridine synthase activity
GS03_RS12705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GS03_RS12725	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GS03_RS12725	COG0047	phosphoribosylformylglycinamidine synthase activity
GS03_RS12780	COG1363	Peptidase, m42
GS03_RS12795	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GS03_RS12800	COG1702	phosphate starvation-inducible protein PhoH
GS03_RS12825	COG0592	DNA-directed DNA polymerase activity
GS03_RS12840	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GS03_RS12845	COG4191	Histidine kinase
GS03_RS12845	COG2205	protein histidine kinase activity
GS03_RS12845	COG0745	RESPONSE REGULATOR receiver
GS03_RS12860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GS03_RS12860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GS03_RS12870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GS03_RS12925	COG4585	Histidine kinase
GS03_RS12930	COG2197	response regulator
GS03_RS12940	COG2195	Cleaves the N-terminal amino acid of tripeptides
GS03_RS12960	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GS03_RS12970	COG1132	(ABC) transporter
GS03_RS12980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GS03_RS12985	COG0297	glycogen (starch) synthase activity
GS03_RS12990	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GS03_RS13000	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GS03_RS13010	COG0336	Belongs to the RNA methyltransferase TrmD family
GS03_RS13015	COG0673	inositol 2-dehydrogenase activity
GS03_RS13020	COG0335	large ribosomal subunit rRNA binding
GS03_RS13025	COG0538	isocitrate dehydrogenase activity
GS03_RS13050	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GS03_RS13055	COG0494	nUDIX hydrolase
GS03_RS13080	COG0556	nucleotide-excision repair
GS03_RS13115	COG2819	hydrolase of the alpha beta superfamily
GS03_RS13130	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GS03_RS13135	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GS03_RS13165	COG0018	arginyl-trna synthetase
GS03_RS13180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GS03_RS13195	COG2885	chlorophyll binding
GS03_RS13205	COG0326	Molecular chaperone. Has ATPase activity
GS03_RS13215	COG3548	integral membrane protein
GS03_RS13220	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GS03_RS13225	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GS03_RS13235	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GS03_RS13240	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GS03_RS13250	COG0028	Belongs to the TPP enzyme family
GS03_RS13280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GS03_RS13295	COG0254	rRNA binding
GS03_RS13305	COG0463	Glycosyl transferase, family 2
GS03_RS13310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GS03_RS13315	COG1132	(ABC) transporter