locus-tag	class	description
FNO75_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FNO75_RS00055	COG0814	amino acid
FNO75_RS00065	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FNO75_RS00070	COG0505	Belongs to the CarA family
FNO75_RS00110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNO75_RS00165	COG1490	D-aminoacyl-tRNA deacylase activity
FNO75_RS00210	COG0574	Belongs to the PEP-utilizing enzyme family
FNO75_RS00210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNO75_RS00220	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FNO75_RS00230	COG1560	Kdo2-lipid A biosynthetic process
FNO75_RS00235	COG1560	Kdo2-lipid A biosynthetic process
FNO75_RS00240	COG0706	membrane insertase activity
FNO75_RS00265	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FNO75_RS00270	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FNO75_RS00275	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FNO75_RS00300	COG0589	response to stress
FNO75_RS00350	COG3038	cytochrome b561
FNO75_RS00370	COG0814	amino acid
FNO75_RS00375	COG0357	Ribosomal RNA small subunit methyltransferase G
FNO75_RS00380	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FNO75_RS00400	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FNO75_RS00405	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNO75_RS00415	COG0268	Binds directly to 16S ribosomal RNA
FNO75_RS00420	COG0481	GTPase activity
FNO75_RS00425	COG0482	sulfurtransferase activity
FNO75_RS00435	COG0242	peptide deformylase activity
FNO75_RS00445	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNO75_RS00445	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNO75_RS00455	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNO75_RS00455	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNO75_RS00495	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FNO75_RS00505	COG0629	single-stranded DNA binding
FNO75_RS00515	COG0857	belongs to the CobB CobQ family
FNO75_RS00515	COG0280	phosphate acetyltransferase
FNO75_RS00520	COG1012	belongs to the aldehyde dehydrogenase family
FNO75_RS00530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FNO75_RS00530	COG3153	acetyltransferase
FNO75_RS00535	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FNO75_RS00545	COG0557	exoribonuclease II activity
FNO75_RS00555	COG0181	hydroxymethylbilane synthase activity
FNO75_RS00560	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FNO75_RS00590	COG1116	anion transmembrane transporter activity
FNO75_RS00605	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FNO75_RS00615	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FNO75_RS00650	COG4067	protein conserved in archaea
FNO75_RS00650	COG0189	ligase activity
FNO75_RS00665	COG0204	Acyl-transferase
FNO75_RS00675	COG0009	L-threonylcarbamoyladenylate synthase
FNO75_RS00685	COG0590	tRNA wobble adenosine to inosine editing
FNO75_RS00690	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNO75_RS00695	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FNO75_RS00725	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FNO75_RS00745	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FNO75_RS00755	COG2862	Uncharacterized protein family, UPF0114
FNO75_RS00760	COG2066	Belongs to the glutaminase family
FNO75_RS00775	COG3040	lipid binding
FNO75_RS00780	COG0814	amino acid
FNO75_RS00785	COG0138	bifunctional purine biosynthesis protein purh
FNO75_RS00790	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FNO75_RS00835	COG1295	ribonuclease BN
FNO75_RS00845	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FNO75_RS00850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNO75_RS00860	COG1294	oxidase, subunit
FNO75_RS00865	COG1271	oxidase subunit
FNO75_RS00880	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FNO75_RS00890	COG0714	Associated with various cellular activities
FNO75_RS00910	COG2304	oxidoreductase activity
FNO75_RS00945	COG0525	valine-tRNA ligase activity
FNO75_RS00985	COG0804	urea catabolic process
FNO75_RS00995	COG0831	urea catabolic process
FNO75_RS01005	COG1304	FMN binding
FNO75_RS01025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FNO75_RS01045	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNO75_RS01050	COG0052	Belongs to the universal ribosomal protein uS2 family
FNO75_RS01055	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FNO75_RS01065	COG0233	cytoplasmic translational termination
FNO75_RS01070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FNO75_RS01075	COG4589	Belongs to the CDS family
FNO75_RS01080	COG0756	dUTP diphosphatase activity
FNO75_RS01085	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FNO75_RS01095	COG0049	tRNA binding
FNO75_RS01100	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FNO75_RS01110	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FNO75_RS01115	COG0088	Forms part of the polypeptide exit tunnel
FNO75_RS01120	COG0089	rRNA binding
FNO75_RS01125	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FNO75_RS01130	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FNO75_RS01135	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FNO75_RS01160	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FNO75_RS01165	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FNO75_RS01170	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FNO75_RS01175	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FNO75_RS01180	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FNO75_RS01185	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FNO75_RS01190	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FNO75_RS01205	COG0200	Binds to the 23S rRNA
FNO75_RS01210	COG0201	protein transport
FNO75_RS01220	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FNO75_RS01230	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FNO75_RS01240	COG0203	ribosomal protein L17
FNO75_RS01250	COG0326	Molecular chaperone. Has ATPase activity
FNO75_RS01260	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FNO75_RS01265	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FNO75_RS01270	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FNO75_RS01285	COG1438	arginine binding
FNO75_RS01290	COG0165	Argininosuccinate lyase
FNO75_RS01295	COG0137	argininosuccinate synthase activity
FNO75_RS01305	COG0504	CTP synthase activity
FNO75_RS01310	COG0105	UTP biosynthetic process
FNO75_RS01315	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FNO75_RS01320	COG0285	dihydrofolate synthase activity
FNO75_RS01325	COG0802	atpase or kinase
FNO75_RS01375	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FNO75_RS01385	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FNO75_RS01405	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FNO75_RS01420	COG0833	amino acid
FNO75_RS01425	COG2945	thiolester hydrolase activity
FNO75_RS01430	COG1494	fructose-1,6-bisphosphatase
FNO75_RS01435	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNO75_RS01475	COG0215	cysteine-tRNA ligase activity
FNO75_RS01480	COG2890	protein-(glutamine-N5) methyltransferase activity
FNO75_RS01490	COG0456	acetyltransferase
FNO75_RS01500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FNO75_RS01555	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FNO75_RS01560	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FNO75_RS01565	COG1127	ABC transporter
FNO75_RS01570	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FNO75_RS01580	COG0850	regulation of cytokinetic process
FNO75_RS01585	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FNO75_RS01590	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FNO75_RS01600	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FNO75_RS01625	COG1051	belongs to the nudix hydrolase family
FNO75_RS01655	COG2985	domain, Protein
FNO75_RS01665	COG2885	chlorophyll binding
FNO75_RS01675	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FNO75_RS01680	COG4401	Chorismate mutase type I
FNO75_RS01795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNO75_RS01860	COG0352	thiamine-phosphate diphosphorylase activity
FNO75_RS01865	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FNO75_RS01870	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FNO75_RS01880	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FNO75_RS01905	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FNO75_RS01915	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FNO75_RS01930	COG0501	Belongs to the peptidase M48B family
FNO75_RS01935	COG1704	LemA family
FNO75_RS01940	COG0583	DNA-binding transcription factor activity
FNO75_RS01960	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FNO75_RS02000	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNO75_RS02000	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNO75_RS02015	COG0833	amino acid
FNO75_RS02020	COG0662	Cupin 2, conserved barrel domain protein
FNO75_RS02020	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FNO75_RS02030	COG0436	Aminotransferase
FNO75_RS02035	COG0497	DNA recombination
FNO75_RS02050	COG4969	Belongs to the N-Me-Phe pilin family
FNO75_RS02060	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FNO75_RS02065	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FNO75_RS02075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FNO75_RS02095	COG0792	nuclease activity
FNO75_RS02100	COG0339	signal peptide processing
FNO75_RS02140	COG1192	Involved in chromosome partitioning
FNO75_RS02145	COG1475	DNA binding
FNO75_RS02150	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FNO75_RS02150	COG0519	Catalyzes the synthesis of GMP from XMP
FNO75_RS02160	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FNO75_RS02175	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FNO75_RS02185	COG0196	riboflavin kinase activity
FNO75_RS02190	COG0281	malic enzyme
FNO75_RS02205	COG1160	GTP binding
FNO75_RS02210	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FNO75_RS02215	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FNO75_RS02225	COG4106	trans-aconitate 2-methyltransferase activity
FNO75_RS02235	COG0537	adenosine 5'-monophosphoramidase activity
FNO75_RS02240	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FNO75_RS02250	COG2226	methyltransferase
FNO75_RS02255	COG0837	glucose binding
FNO75_RS02265	COG2917	probably involved in intracellular septation
FNO75_RS02270	COG0009	L-threonylcarbamoyladenylate synthase
FNO75_RS02330	COG1994	Peptidase M50
FNO75_RS02340	COG0688	phosphatidylethanolamine metabolic process
FNO75_RS02350	COG1056	cytidyltransferase-related domain
FNO75_RS02350	COG1051	belongs to the nudix hydrolase family
FNO75_RS02355	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FNO75_RS02360	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNO75_RS02385	COG0024	Methionine aminopeptidase
FNO75_RS02400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FNO75_RS02410	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FNO75_RS02425	COG0668	transmembrane transport
FNO75_RS02430	COG0587	DNA-directed DNA polymerase activity
FNO75_RS02475	COG1982	Orn Lys Arg decarboxylase major
FNO75_RS02480	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FNO75_RS02490	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FNO75_RS02510	COG2873	o-acetylhomoserine
FNO75_RS02525	COG1523	belongs to the glycosyl hydrolase 13 family
FNO75_RS02530	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FNO75_RS02535	COG0033	Phosphoglucomutase
FNO75_RS02540	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FNO75_RS02545	COG0297	glycogen (starch) synthase activity
FNO75_RS02550	COG0058	SHG alpha-glucan phosphorylase activity
FNO75_RS02555	COG1640	4-alpha-glucanotransferase
FNO75_RS02570	COG0752	glycyl-tRNA synthetase alpha subunit
FNO75_RS02585	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FNO75_RS02595	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FNO75_RS02600	COG0527	aspartate kinase activity
FNO75_RS02600	COG0460	homoserine dehydrogenase
FNO75_RS02610	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FNO75_RS02625	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FNO75_RS02630	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FNO75_RS02645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FNO75_RS02650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNO75_RS02675	COG0488	(ABC) transporter
FNO75_RS02685	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FNO75_RS02690	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FNO75_RS02695	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNO75_RS02700	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FNO75_RS02705	COG0772	Belongs to the SEDS family
FNO75_RS02715	COG0463	Glycosyl transferase, family 2
FNO75_RS02725	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FNO75_RS02735	COG0625	glutathione transferase activity
FNO75_RS02740	COG0616	signal peptide processing
FNO75_RS02745	COG0470	DNA polymerase III
FNO75_RS02755	COG0113	porphobilinogen synthase activity
FNO75_RS02760	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FNO75_RS02785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FNO75_RS02790	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FNO75_RS02795	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FNO75_RS02800	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FNO75_RS02810	COG0439	Biotin carboxylase
FNO75_RS02820	COG0668	transmembrane transport
FNO75_RS02825	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FNO75_RS02830	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FNO75_RS02830	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FNO75_RS02835	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FNO75_RS02845	COG0531	amino acid
FNO75_RS02875	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FNO75_RS02890	COG0492	ferredoxin-NADP+ reductase activity
FNO75_RS02960	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FNO75_RS02965	COG0045	succinate-CoA ligase (ADP-forming) activity
FNO75_RS02980	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FNO75_RS02995	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FNO75_RS03000	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FNO75_RS03005	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FNO75_RS03010	COG0204	Acyl-transferase
FNO75_RS03010	COG0318	PFAM AMP-dependent synthetase and ligase
FNO75_RS03015	COG0275	rRNA processing
FNO75_RS03020	COG3116	cell division
FNO75_RS03030	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FNO75_RS03035	COG1185	polyribonucleotide nucleotidyltransferase activity
FNO75_RS03040	COG0316	Belongs to the HesB IscA family
FNO75_RS03045	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FNO75_RS03050	COG0572	uridine kinase
FNO75_RS03055	COG1758	RNA polymerase activity
FNO75_RS03105	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FNO75_RS03110	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FNO75_RS03115	COG0814	amino acid
FNO75_RS03120	COG1063	alcohol dehydrogenase
FNO75_RS03125	COG0156	8-amino-7-oxononanoate synthase activity
FNO75_RS03130	COG0534	Mate efflux family protein
FNO75_RS03140	COG0477	Major facilitator Superfamily
FNO75_RS03145	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FNO75_RS03150	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FNO75_RS03160	COG2271	Major facilitator Superfamily
FNO75_RS03165	COG0584	glycerophosphoryl diester phosphodiesterase
FNO75_RS03190	COG0251	oxidation-reduction process
FNO75_RS03225	COG0653	protein targeting
FNO75_RS03230	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FNO75_RS03235	COG4988	ABC transporter
FNO75_RS03260	COG1940	carbohydrate kinase activity
FNO75_RS03280	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FNO75_RS03285	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FNO75_RS03290	COG0247	lactate metabolic process
FNO75_RS03290	COG0277	FAD linked oxidase domain protein
FNO75_RS03305	COG0295	cytidine deaminase activity
FNO75_RS03310	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FNO75_RS03320	COG2860	membrane
FNO75_RS03325	COG0742	ribosomal rna small subunit methyltransferase
FNO75_RS03335	COG0612	Peptidase, M16
FNO75_RS03340	COG0795	lipopolysaccharide-transporting ATPase activity
FNO75_RS03345	COG0795	lipopolysaccharide-transporting ATPase activity
FNO75_RS03350	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FNO75_RS03355	COG0517	IMP dehydrogenase activity
FNO75_RS03355	COG0516	GMP reductase activity
FNO75_RS03365	COG0166	Belongs to the GPI family
FNO75_RS03375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FNO75_RS03380	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FNO75_RS03390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FNO75_RS03395	COG0813	purine-nucleoside phosphorylase activity
FNO75_RS03410	COG0653	protein targeting
FNO75_RS03415	COG0519	Catalyzes the synthesis of GMP from XMP
FNO75_RS03425	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FNO75_RS03430	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FNO75_RS03440	COG1177	transmembrane transport
FNO75_RS03445	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNO75_RS03450	COG3842	ATPase activity
FNO75_RS03480	COG3104	oligopeptide transport
FNO75_RS03485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FNO75_RS03490	COG0531	amino acid
FNO75_RS03495	COG1605	Chorismate mutase
FNO75_RS03495	COG0077	Prephenate dehydratase
FNO75_RS03510	COG1760	l-serine dehydratase
FNO75_RS03515	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FNO75_RS03520	COG0316	Belongs to the HesB IscA family
FNO75_RS03525	COG2151	metal-sulfur cluster biosynthetic enzyme
FNO75_RS03530	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FNO75_RS03535	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FNO75_RS03560	COG1058	Belongs to the CinA family
FNO75_RS03560	COG1546	Belongs to the CinA family
FNO75_RS03565	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FNO75_RS03565	COG0189	ligase activity
FNO75_RS03570	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNO75_RS03570	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FNO75_RS03575	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FNO75_RS03580	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FNO75_RS03585	COG0814	amino acid
FNO75_RS03595	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FNO75_RS03600	COG0343	queuine tRNA-ribosyltransferase activity
FNO75_RS03615	COG1335	isochorismatase
FNO75_RS03635	COG1862	Preprotein translocase
FNO75_RS03640	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FNO75_RS03645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FNO75_RS03655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FNO75_RS03670	COG0328	RNA-DNA hybrid ribonuclease activity
FNO75_RS03675	COG0252	asparaginase activity
FNO75_RS03680	COG0288	reversible hydration of carbon dioxide
FNO75_RS03695	COG0544	peptidyl-prolyl cis-trans isomerase activity
FNO75_RS03700	COG0740	serine-type endopeptidase activity
FNO75_RS03705	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FNO75_RS03710	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FNO75_RS03725	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FNO75_RS03730	COG1923	regulation of RNA biosynthetic process
FNO75_RS03735	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FNO75_RS03745	COG0330	HflC and HflK could
FNO75_RS03750	COG0330	HflC and HflK could
FNO75_RS03755	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNO75_RS03760	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FNO75_RS03775	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNO75_RS03800	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FNO75_RS03805	COG0670	Belongs to the BI1 family
FNO75_RS03820	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FNO75_RS03825	COG2878	Part of a membrane complex involved in electron transport
FNO75_RS03830	COG2999	glutathione oxidoreductase activity
FNO75_RS03840	COG1528	Iron-storage protein
FNO75_RS03845	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FNO75_RS03850	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FNO75_RS03855	COG0217	transcriptional regulatory protein
FNO75_RS03860	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FNO75_RS03865	COG2271	Major facilitator Superfamily
FNO75_RS03875	COG1322	Protein conserved in bacteria
FNO75_RS03925	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FNO75_RS03930	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FNO75_RS03935	COG4536	flavin adenine dinucleotide binding
FNO75_RS03950	COG0193	aminoacyl-tRNA hydrolase activity
FNO75_RS03965	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FNO75_RS03975	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FNO75_RS03985	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FNO75_RS03990	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FNO75_RS04000	COG0095	Lipoate-protein ligase
FNO75_RS04005	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FNO75_RS04025	COG2301	Belongs to the HpcH HpaI aldolase family
FNO75_RS04040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FNO75_RS04055	COG1566	PFAM secretion protein HlyD family protein
FNO75_RS04070	COG1509	lysine 2,3-aminomutase activity
FNO75_RS04080	COG1278	Cold shock
FNO75_RS04105	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FNO75_RS04110	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FNO75_RS04115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNO75_RS04155	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FNO75_RS04160	COG0084	hydrolase, TatD family'
FNO75_RS04165	COG0751	glycine-tRNA ligase activity
FNO75_RS04175	COG2814	Major facilitator Superfamily
FNO75_RS04200	COG0301	tRNA thio-modification
FNO75_RS04210	COG2835	tetraacyldisaccharide 4'-kinase activity
FNO75_RS04215	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FNO75_RS04235	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FNO75_RS04245	COG2814	Major facilitator Superfamily
FNO75_RS04250	COG2814	Major facilitator Superfamily
FNO75_RS04255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FNO75_RS04260	COG0513	Belongs to the DEAD box helicase family
FNO75_RS04270	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FNO75_RS04280	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FNO75_RS04295	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FNO75_RS04300	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FNO75_RS04305	COG0408	coproporphyrinogen oxidase activity
FNO75_RS04310	COG1054	Belongs to the UPF0176 family
FNO75_RS04435	COG3321	synthase
FNO75_RS04435	COG4221	oxidoreductase activity
FNO75_RS04435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNO75_RS04435	COG1028	Short-chain dehydrogenase reductase Sdr
FNO75_RS04490	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FNO75_RS04490	COG0116	Belongs to the methyltransferase superfamily
FNO75_RS04495	COG2076	Multidrug Resistance protein
FNO75_RS04510	COG0640	Transcriptional regulator
FNO75_RS04520	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FNO75_RS04525	COG0189	ligase activity
FNO75_RS04530	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNO75_RS04545	COG1017	nitric oxide dioxygenase activity
FNO75_RS04545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FNO75_RS04550	COG1472	Belongs to the glycosyl hydrolase 3 family
FNO75_RS04570	COG1940	carbohydrate kinase activity
FNO75_RS04590	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FNO75_RS04590	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FNO75_RS04600	COG0512	Glutamine amidotransferase of anthranilate synthase
FNO75_RS04600	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FNO75_RS04605	COG0512	Glutamine amidotransferase of anthranilate synthase
FNO75_RS04605	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FNO75_RS04645	COG3104	oligopeptide transport
FNO75_RS04655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNO75_RS04675	COG0708	Exodeoxyribonuclease III
FNO75_RS04700	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FNO75_RS04705	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FNO75_RS04715	COG0730	response to heat
FNO75_RS04730	COG0531	amino acid
FNO75_RS04735	COG0569	domain protein
FNO75_RS04745	COG0719	Fe-S assembly protein
FNO75_RS04750	COG0396	ATPase activity
FNO75_RS04755	COG0719	Fe-S assembly protein
FNO75_RS04765	COG3118	belongs to the thioredoxin family
FNO75_RS04775	COG0833	amino acid
FNO75_RS04780	COG0494	nUDIX hydrolase
FNO75_RS04785	COG1678	Uncharacterized ACR, COG1678
FNO75_RS04790	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FNO75_RS04795	COG0495	leucyl-tRNA aminoacylation
FNO75_RS04805	COG0668	transmembrane transport
FNO75_RS04810	COG0717	Belongs to the dCTP deaminase family
FNO75_RS04815	COG0489	protein tyrosine kinase activity
FNO75_RS04830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FNO75_RS04850	COG0735	belongs to the Fur family
FNO75_RS04865	COG0730	response to heat
FNO75_RS04870	COG0072	phenylalanine-tRNA ligase activity
FNO75_RS04870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNO75_RS04875	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FNO75_RS04910	COG3655	Transcriptional regulator
FNO75_RS04925	COG2255	four-way junction helicase activity
FNO75_RS04940	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FNO75_RS04945	COG0519	Catalyzes the synthesis of GMP from XMP
FNO75_RS04945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FNO75_RS04950	COG0101	tRNA pseudouridine synthase activity
FNO75_RS04965	COG1137	ATPase activity
FNO75_RS04980	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FNO75_RS04985	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FNO75_RS04990	COG1686	Belongs to the peptidase S11 family
FNO75_RS04995	COG2921	Belongs to the UPF0250 family
FNO75_RS05020	COG1610	YqeY-like protein
FNO75_RS05030	COG2027	D-alanyl-D-alanine carboxypeptidase
FNO75_RS05045	COG0037	tRNA processing
FNO75_RS05055	COG0142	geranyltranstransferase activity
FNO75_RS05080	COG1187	pseudouridine synthase activity
FNO75_RS05090	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FNO75_RS05100	COG0359	binds to the 23S rRNA
FNO75_RS05105	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FNO75_RS05110	COG0360	Binds together with S18 to 16S ribosomal RNA
FNO75_RS05115	COG2996	Protein conserved in bacteria
FNO75_RS05120	COG0210	DNA helicase
FNO75_RS05125	COG0354	folic acid binding
FNO75_RS05140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FNO75_RS05150	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FNO75_RS05160	COG0210	DNA helicase
FNO75_RS05200	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNO75_RS05215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNO75_RS05275	COG0386	Belongs to the glutathione peroxidase family
FNO75_RS05300	COG0583	DNA-binding transcription factor activity
FNO75_RS05310	COG2132	Multicopper oxidase
FNO75_RS05330	COG1876	peptidase activity
FNO75_RS05365	COG0450	alkyl hydroperoxide reductase
FNO75_RS05380	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FNO75_RS05410	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FNO75_RS05420	COG0039	L-malate dehydrogenase activity
FNO75_RS05430	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FNO75_RS05435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNO75_RS05450	COG0488	(ABC) transporter
FNO75_RS05495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FNO75_RS05500	COG2264	protein methyltransferase activity
FNO75_RS05520	COG0415	Belongs to the DNA photolyase family
FNO75_RS05525	COG0148	phosphopyruvate hydratase activity
FNO75_RS05535	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FNO75_RS05540	COG2814	Major facilitator Superfamily
FNO75_RS05555	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FNO75_RS05575	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FNO75_RS05605	COG0563	adenylate kinase activity
FNO75_RS05610	COG0277	FAD linked oxidase domain protein
FNO75_RS05620	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FNO75_RS05625	COG0436	Aminotransferase
FNO75_RS05635	COG1214	PFAM Peptidase M22, glycoprotease
FNO75_RS05645	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FNO75_RS05660	COG4122	O-methyltransferase activity
FNO75_RS05665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNO75_RS05670	COG1702	phosphate starvation-inducible protein PhoH
FNO75_RS05680	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FNO75_RS05685	COG4535	Mg2 and Co2 transporter CorC
FNO75_RS05690	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FNO75_RS05715	COG1496	oxidoreductase activity
FNO75_RS05740	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FNO75_RS05745	COG2814	Major facilitator Superfamily
FNO75_RS05750	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNO75_RS05755	COG1823	symporter activity
FNO75_RS05760	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FNO75_RS05775	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FNO75_RS05785	COG1217	gtp-binding protein TYPA
FNO75_RS05810	COG0405	Gamma-glutamyltransferase
FNO75_RS05820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNO75_RS05820	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FNO75_RS05825	COG2914	Belongs to the UPF0125 (RnfH) family
FNO75_RS05830	COG2867	negative regulation of translational initiation
FNO75_RS05835	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FNO75_RS05840	COG0037	tRNA processing
FNO75_RS05845	COG0076	glutamate decarboxylase activity
FNO75_RS05900	COG1570	exodeoxyribonuclease VII activity
FNO75_RS05935	COG0477	Major facilitator Superfamily
FNO75_RS05950	COG0556	nucleotide-excision repair
FNO75_RS05955	COG2925	Exonuclease
FNO75_RS05960	COG4221	oxidoreductase activity
FNO75_RS05980	COG0445	tRNA wobble uridine modification
FNO75_RS05995	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FNO75_RS06020	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FNO75_RS06030	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FNO75_RS06035	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FNO75_RS06050	COG0509	glycine decarboxylation via glycine cleavage system
FNO75_RS06055	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FNO75_RS06060	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FNO75_RS06065	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FNO75_RS06070	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FNO75_RS06120	COG1446	asparaginase
FNO75_RS06130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNO75_RS06160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNO75_RS06185	COG2089	acid synthase
FNO75_RS06190	COG1083	cytidylyl-transferase
FNO75_RS06200	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FNO75_RS06220	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FNO75_RS06230	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FNO75_RS06235	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FNO75_RS06235	COG0517	IMP dehydrogenase activity
FNO75_RS06250	COG3220	belongs to the UPF0276 family
FNO75_RS06270	COG1611	Belongs to the LOG family
FNO75_RS06290	COG0346	lactoylglutathione lyase activity
FNO75_RS06295	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FNO75_RS06320	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FNO75_RS06335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNO75_RS06340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNO75_RS06345	COG3079	Belongs to the UPF0149 family
FNO75_RS06365	COG0586	Pfam SNARE associated Golgi protein
FNO75_RS06370	COG0586	Pfam SNARE associated Golgi protein
FNO75_RS06375	COG1381	Involved in DNA repair and RecF pathway recombination
FNO75_RS06385	COG1104	cysteine desulfurase activity
FNO75_RS06390	COG1530	ribonuclease E activity
FNO75_RS06395	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FNO75_RS06400	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FNO75_RS06405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNO75_RS06410	COG0037	tRNA processing
FNO75_RS06415	COG3104	oligopeptide transport
FNO75_RS06445	COG3028	Belongs to the UPF0307 family
FNO75_RS06450	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNO75_RS06465	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNO75_RS06470	COG0564	pseudouridine synthase activity
FNO75_RS06480	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FNO75_RS06485	COG1127	ABC transporter
FNO75_RS06505	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FNO75_RS06525	COG0477	Major facilitator Superfamily
FNO75_RS06540	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FNO75_RS06555	COG0484	heat shock protein binding
FNO75_RS06560	COG0443	Heat shock 70 kDa protein
FNO75_RS06565	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FNO75_RS06570	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FNO75_RS06585	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FNO75_RS06590	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FNO75_RS06625	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FNO75_RS06650	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FNO75_RS06660	COG0583	DNA-binding transcription factor activity
FNO75_RS06670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNO75_RS06810	COG0191	fructose-bisphosphate aldolase activity
FNO75_RS06815	COG0469	pyruvate kinase activity
FNO75_RS06820	COG0126	phosphoglycerate kinase activity
FNO75_RS06835	COG1399	metal-binding, possibly nucleic acid-binding protein
FNO75_RS06840	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FNO75_RS06845	COG0416	fatty acid biosynthetic process
FNO75_RS06855	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FNO75_RS06860	COG1028	Short-chain dehydrogenase reductase Sdr
FNO75_RS06865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNO75_RS06870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNO75_RS06890	COG2855	membrane
FNO75_RS06895	COG0483	inositol monophosphate 1-phosphatase activity
FNO75_RS06900	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FNO75_RS06900	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FNO75_RS06915	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FNO75_RS06930	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FNO75_RS06945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FNO75_RS06950	COG1074	ATP-dependent DNA helicase activity
FNO75_RS06980	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FNO75_RS06985	COG0069	glutamate synthase activity
FNO75_RS07030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNO75_RS07050	COG2166	iron-sulfur cluster assembly
FNO75_RS07065	COG0442	prolyl-tRNA aminoacylation
FNO75_RS07080	COG0436	Aminotransferase
FNO75_RS07110	COG2983	Belongs to the UPF0260 family
FNO75_RS07150	COG0402	S-adenosylhomocysteine deaminase activity
FNO75_RS07165	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FNO75_RS07170	COG1280	lysine exporter protein (LysE YggA)
FNO75_RS07180	COG0463	Glycosyl transferase, family 2
FNO75_RS07185	COG0842	Transport permease protein
FNO75_RS07190	COG1131	(ABC) transporter
FNO75_RS07200	COG0730	response to heat
FNO75_RS07215	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FNO75_RS07215	COG3264	Mechanosensitive ion channel
FNO75_RS07230	COG0084	hydrolase, TatD family'
FNO75_RS07250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FNO75_RS07255	COG0248	Ppx GppA phosphatase
FNO75_RS07295	COG1216	Glycosyl transferase, family 2
FNO75_RS07305	COG1682	transport, permease protein
FNO75_RS07315	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNO75_RS07315	COG2755	lipolytic protein G-D-S-L family
FNO75_RS07325	COG1216	Glycosyl transferase, family 2
FNO75_RS07325	COG1442	glycosyl transferase family 8
FNO75_RS07370	COG1028	Short-chain dehydrogenase reductase Sdr
FNO75_RS07410	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FNO75_RS07430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNO75_RS07445	COG1088	dTDP-glucose 4,6-dehydratase activity
FNO75_RS07465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNO75_RS07470	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FNO75_RS07475	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FNO75_RS07475	COG0662	Cupin 2, conserved barrel domain protein
FNO75_RS07485	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FNO75_RS07490	COG1086	Polysaccharide biosynthesis protein
FNO75_RS07495	COG1643	Atp-dependent helicase
FNO75_RS07510	COG0318	PFAM AMP-dependent synthetase and ligase
FNO75_RS07515	COG1960	acyl-CoA dehydrogenase activity
FNO75_RS07520	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNO75_RS07520	COG1024	Enoyl-CoA hydratase
FNO75_RS07525	COG0183	Belongs to the thiolase family
FNO75_RS07550	COG0010	Belongs to the arginase family
FNO75_RS07580	COG0500	methyltransferase
FNO75_RS07625	COG1028	Short-chain dehydrogenase reductase Sdr
FNO75_RS07635	COG0557	exoribonuclease II activity
FNO75_RS07645	COG0571	ribonuclease III activity
FNO75_RS07650	COG0681	Belongs to the peptidase S26 family
FNO75_RS07660	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FNO75_RS07665	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FNO75_RS07670	COG1519	Transferase
FNO75_RS07675	COG0142	geranyltranstransferase activity
FNO75_RS07680	COG1183	phosphatidylcholine synthase activity
FNO75_RS07730	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FNO75_RS07735	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FNO75_RS07740	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FNO75_RS07790	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FNO75_RS07795	COG3104	oligopeptide transport
FNO75_RS07800	COG3104	oligopeptide transport
FNO75_RS07805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNO75_RS07810	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNO75_RS07825	COG0237	dephospho-CoA kinase activity
FNO75_RS07845	COG0180	Tryptophanyl-tRNA synthetase
FNO75_RS07870	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FNO75_RS07890	COG0825	malonyl-CoA metabolic process
FNO75_RS07895	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FNO75_RS07905	COG0814	amino acid
FNO75_RS07910	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FNO75_RS07915	COG0742	ribosomal rna small subunit methyltransferase
FNO75_RS07935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FNO75_RS07950	COG0814	amino acid
FNO75_RS07980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNO75_RS07985	COG0398	Pfam SNARE associated Golgi protein
FNO75_RS07995	COG0531	amino acid
FNO75_RS08010	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FNO75_RS08020	COG2081	HI0933 family
FNO75_RS08035	COG0300	oxidoreductase activity
FNO75_RS08045	COG0459	protein refolding
FNO75_RS08050	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FNO75_RS08065	COG1918	ferrous iron import across plasma membrane
FNO75_RS08070	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FNO75_RS08085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNO75_RS08090	COG1028	Short-chain dehydrogenase reductase Sdr
FNO75_RS08100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNO75_RS08115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNO75_RS08120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNO75_RS08140	COG0463	Glycosyl transferase, family 2
FNO75_RS08180	COG3022	response to hydroperoxide
FNO75_RS08185	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FNO75_RS08190	COG2890	protein-(glutamine-N5) methyltransferase activity
FNO75_RS08195	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FNO75_RS08200	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FNO75_RS08210	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNO75_RS08215	COG2814	Major facilitator Superfamily
FNO75_RS08225	COG0814	amino acid
FNO75_RS08245	COG0494	nUDIX hydrolase
FNO75_RS08280	COG4974	Belongs to the 'phage' integrase family
FNO75_RS08285	COG0335	large ribosomal subunit rRNA binding
FNO75_RS08290	COG0336	Belongs to the RNA methyltransferase TrmD family
FNO75_RS08295	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FNO75_RS08300	COG0228	four-way junction DNA binding
FNO75_RS08305	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FNO75_RS08315	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FNO75_RS08325	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FNO75_RS08330	COG0085	RNA polymerase activity
FNO75_RS08335	COG0222	ribosome binding
FNO75_RS08340	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FNO75_RS08345	COG0081	regulation of translation
FNO75_RS08350	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FNO75_RS08360	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FNO75_RS08370	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FNO75_RS08405	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FNO75_RS08410	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FNO75_RS08415	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNO75_RS08430	COG2814	Major facilitator Superfamily
FNO75_RS08455	COG0210	DNA helicase
FNO75_RS08460	COG0552	protein localization to endoplasmic reticulum
FNO75_RS08470	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FNO75_RS08475	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FNO75_RS08485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FNO75_RS08490	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FNO75_RS08495	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FNO75_RS08505	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNO75_RS08505	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNO75_RS08510	COG1663	tetraacyldisaccharide 4'-kinase activity
FNO75_RS08530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNO75_RS08535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNO75_RS08565	COG0642	Histidine kinase
FNO75_RS08570	COG1090	epimerase
FNO75_RS08575	COG1271	oxidase subunit
FNO75_RS08585	COG1294	oxidase, subunit
FNO75_RS08620	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FNO75_RS08640	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FNO75_RS08645	COG0149	triose-phosphate isomerase activity
FNO75_RS08650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNO75_RS08655	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FNO75_RS08670	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FNO75_RS08675	COG1053	succinate dehydrogenase
FNO75_RS08680	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FNO75_RS08685	COG2009	succinate dehydrogenase
FNO75_RS08695	COG2223	nitrite transmembrane transporter activity
FNO75_RS08700	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FNO75_RS08705	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FNO75_RS08715	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FNO75_RS08720	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FNO75_RS08725	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FNO75_RS08730	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FNO75_RS08735	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FNO75_RS08740	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FNO75_RS08765	COG0564	pseudouridine synthase activity
FNO75_RS08770	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FNO75_RS08780	COG0124	histidyl-tRNA synthetase
FNO75_RS08785	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FNO75_RS08790	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FNO75_RS08795	COG2251	uridine kinase activity
FNO75_RS08795	COG0195	Participates in both transcription termination and antitermination
FNO75_RS08800	COG0779	Required for maturation of 30S ribosomal subunits
FNO75_RS08810	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FNO75_RS08840	COG0713	ATP synthesis coupled electron transport
FNO75_RS08845	COG0839	Belongs to the complex I subunit 6 family
FNO75_RS08850	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNO75_RS08855	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FNO75_RS08860	COG1034	ATP synthesis coupled electron transport
FNO75_RS08870	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FNO75_RS08875	COG0649	NAD binding
FNO75_RS08880	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNO75_RS08890	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNO75_RS08960	COG0154	amidase activity
FNO75_RS08965	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FNO75_RS08980	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FNO75_RS08990	COG0270	DNA (cytosine-5-)-methyltransferase activity
FNO75_RS08995	COG0047	phosphoribosylformylglycinamidine synthase activity
FNO75_RS08995	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FNO75_RS09000	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FNO75_RS09015	COG1538	Outer membrane efflux protein
FNO75_RS09025	COG0826	peptidase U32
FNO75_RS09040	COG2814	Major facilitator Superfamily
FNO75_RS09045	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FNO75_RS09050	COG4178	(ABC) transporter
FNO75_RS09055	COG0531	amino acid
FNO75_RS09060	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FNO75_RS09065	COG0814	amino acid
FNO75_RS09085	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FNO75_RS09090	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FNO75_RS09095	COG1733	regulation of RNA biosynthetic process
FNO75_RS09110	COG2271	Major facilitator Superfamily
FNO75_RS09175	COG0084	hydrolase, TatD family'
FNO75_RS09180	COG3201	nicotinamide mononucleotide transporter
FNO75_RS09225	COG0542	response to heat
FNO75_RS09250	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FNO75_RS09260	COG0204	Acyl-transferase
FNO75_RS09285	COG0545	Peptidyl-prolyl cis-trans isomerase
FNO75_RS09305	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FNO75_RS09355	COG0488	(ABC) transporter
FNO75_RS09415	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNO75_RS09425	COG0512	Glutamine amidotransferase of anthranilate synthase