locus-tag	class	description
OOM_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OOM_RS00050	COG0814	amino acid
OOM_RS00060	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OOM_RS00065	COG0505	Belongs to the CarA family
OOM_RS00105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OOM_RS00150	COG1490	D-aminoacyl-tRNA deacylase activity
OOM_RS00205	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OOM_RS00205	COG0574	Belongs to the PEP-utilizing enzyme family
OOM_RS00215	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OOM_RS00225	COG1560	Kdo2-lipid A biosynthetic process
OOM_RS00230	COG1560	Kdo2-lipid A biosynthetic process
OOM_RS00235	COG0706	membrane insertase activity
OOM_RS00260	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OOM_RS00265	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OOM_RS00270	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OOM_RS00295	COG0589	response to stress
OOM_RS00345	COG3038	cytochrome b561
OOM_RS00365	COG0814	amino acid
OOM_RS00370	COG0357	Ribosomal RNA small subunit methyltransferase G
OOM_RS00375	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OOM_RS00390	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OOM_RS00395	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OOM_RS00405	COG0268	Binds directly to 16S ribosomal RNA
OOM_RS00410	COG0481	GTPase activity
OOM_RS00415	COG0482	sulfurtransferase activity
OOM_RS00425	COG0242	peptide deformylase activity
OOM_RS00435	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OOM_RS00435	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OOM_RS00445	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OOM_RS00445	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OOM_RS00490	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OOM_RS00500	COG0629	single-stranded DNA binding
OOM_RS00510	COG0280	phosphate acetyltransferase
OOM_RS00510	COG0857	belongs to the CobB CobQ family
OOM_RS00515	COG1012	belongs to the aldehyde dehydrogenase family
OOM_RS00525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OOM_RS00525	COG3153	acetyltransferase
OOM_RS00530	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OOM_RS00540	COG0557	exoribonuclease II activity
OOM_RS00550	COG0181	hydroxymethylbilane synthase activity
OOM_RS00555	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OOM_RS00575	COG1116	anion transmembrane transporter activity
OOM_RS00590	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OOM_RS00600	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OOM_RS00635	COG4067	protein conserved in archaea
OOM_RS00635	COG0189	ligase activity
OOM_RS00650	COG0204	Acyl-transferase
OOM_RS00660	COG0009	L-threonylcarbamoyladenylate synthase
OOM_RS00670	COG0590	tRNA wobble adenosine to inosine editing
OOM_RS00675	COG1181	Belongs to the D-alanine--D-alanine ligase family
OOM_RS00680	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OOM_RS00710	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OOM_RS00730	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OOM_RS00740	COG2862	Uncharacterized protein family, UPF0114
OOM_RS00745	COG2066	Belongs to the glutaminase family
OOM_RS00760	COG3040	lipid binding
OOM_RS00765	COG0814	amino acid
OOM_RS00770	COG0138	bifunctional purine biosynthesis protein purh
OOM_RS00775	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OOM_RS00820	COG1295	ribonuclease BN
OOM_RS00830	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OOM_RS00835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OOM_RS00840	COG1294	oxidase, subunit
OOM_RS00845	COG1271	oxidase subunit
OOM_RS00860	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
OOM_RS00870	COG0714	Associated with various cellular activities
OOM_RS00890	COG2304	oxidoreductase activity
OOM_RS00925	COG0525	valine-tRNA ligase activity
OOM_RS00965	COG0804	urea catabolic process
OOM_RS00970	COG0832	Belongs to the urease beta subunit family
OOM_RS00975	COG0831	urea catabolic process
OOM_RS00985	COG1304	FMN binding
OOM_RS01005	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OOM_RS01025	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OOM_RS01030	COG0052	Belongs to the universal ribosomal protein uS2 family
OOM_RS01035	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OOM_RS01045	COG0233	cytoplasmic translational termination
OOM_RS01050	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OOM_RS01055	COG4589	Belongs to the CDS family
OOM_RS01060	COG0756	dUTP diphosphatase activity
OOM_RS01065	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OOM_RS01075	COG0049	tRNA binding
OOM_RS01080	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OOM_RS01090	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OOM_RS01095	COG0088	Forms part of the polypeptide exit tunnel
OOM_RS01100	COG0089	rRNA binding
OOM_RS01105	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OOM_RS01110	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OOM_RS01115	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OOM_RS01140	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OOM_RS01145	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OOM_RS01150	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OOM_RS01155	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OOM_RS01160	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OOM_RS01165	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OOM_RS01170	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OOM_RS01185	COG0200	Binds to the 23S rRNA
OOM_RS01190	COG0201	protein transport
OOM_RS01200	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OOM_RS01210	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OOM_RS01220	COG0203	ribosomal protein L17
OOM_RS01230	COG0326	Molecular chaperone. Has ATPase activity
OOM_RS01245	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OOM_RS01250	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OOM_RS01255	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OOM_RS01270	COG1438	arginine binding
OOM_RS01275	COG0165	Argininosuccinate lyase
OOM_RS01280	COG0137	argininosuccinate synthase activity
OOM_RS01290	COG0504	CTP synthase activity
OOM_RS01295	COG0105	UTP biosynthetic process
OOM_RS01300	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OOM_RS01305	COG0285	dihydrofolate synthase activity
OOM_RS01310	COG0802	atpase or kinase
OOM_RS01360	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
OOM_RS01370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OOM_RS01390	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OOM_RS01405	COG0833	amino acid
OOM_RS01415	COG1494	fructose-1,6-bisphosphatase
OOM_RS01420	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OOM_RS01465	COG0215	cysteine-tRNA ligase activity
OOM_RS01470	COG2890	protein-(glutamine-N5) methyltransferase activity
OOM_RS01480	COG0456	acetyltransferase
OOM_RS01490	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OOM_RS01545	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OOM_RS01550	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OOM_RS01555	COG1127	ABC transporter
OOM_RS01560	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
OOM_RS01570	COG0850	regulation of cytokinetic process
OOM_RS01575	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OOM_RS01580	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OOM_RS01590	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OOM_RS01615	COG1051	belongs to the nudix hydrolase family
OOM_RS01645	COG2985	domain, Protein
OOM_RS01655	COG2885	chlorophyll binding
OOM_RS01665	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OOM_RS01670	COG4401	Chorismate mutase type I
OOM_RS01775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OOM_RS01830	COG0352	thiamine-phosphate diphosphorylase activity
OOM_RS01835	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OOM_RS01840	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OOM_RS01850	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OOM_RS01870	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OOM_RS01880	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OOM_RS01900	COG0501	Belongs to the peptidase M48B family
OOM_RS01905	COG1704	LemA family
OOM_RS01910	COG0583	DNA-binding transcription factor activity
OOM_RS01930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OOM_RS01970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OOM_RS01970	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OOM_RS01985	COG0833	amino acid
OOM_RS01990	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
OOM_RS01990	COG0662	Cupin 2, conserved barrel domain protein
OOM_RS02000	COG0436	Aminotransferase
OOM_RS02005	COG0497	DNA recombination
OOM_RS02020	COG4969	Belongs to the N-Me-Phe pilin family
OOM_RS02030	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OOM_RS02035	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OOM_RS02045	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OOM_RS02065	COG0792	nuclease activity
OOM_RS02070	COG0339	signal peptide processing
OOM_RS02110	COG1192	Involved in chromosome partitioning
OOM_RS02115	COG1475	DNA binding
OOM_RS02120	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OOM_RS02120	COG0519	Catalyzes the synthesis of GMP from XMP
OOM_RS02130	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
OOM_RS02145	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OOM_RS02155	COG0196	riboflavin kinase activity
OOM_RS02160	COG0281	malic enzyme
OOM_RS02175	COG1160	GTP binding
OOM_RS02180	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OOM_RS02185	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OOM_RS02195	COG4106	trans-aconitate 2-methyltransferase activity
OOM_RS02210	COG0537	adenosine 5'-monophosphoramidase activity
OOM_RS02215	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OOM_RS02225	COG2226	methyltransferase
OOM_RS02230	COG0837	glucose binding
OOM_RS02240	COG2917	probably involved in intracellular septation
OOM_RS02245	COG0009	L-threonylcarbamoyladenylate synthase
OOM_RS02290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OOM_RS02300	COG0583	DNA-binding transcription factor activity
OOM_RS02310	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OOM_RS02365	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OOM_RS02370	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OOM_RS02385	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
OOM_RS02390	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OOM_RS02395	COG0443	Heat shock 70 kDa protein
OOM_RS02400	COG0484	heat shock protein binding
OOM_RS02415	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OOM_RS02430	COG0477	Major facilitator Superfamily
OOM_RS02450	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OOM_RS02470	COG1127	ABC transporter
OOM_RS02475	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OOM_RS02485	COG0564	pseudouridine synthase activity
OOM_RS02490	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OOM_RS02550	COG1538	Outer membrane efflux protein
OOM_RS02565	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OOM_RS02570	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OOM_RS02570	COG0047	phosphoribosylformylglycinamidine synthase activity
OOM_RS02580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OOM_RS02595	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OOM_RS02600	COG0154	amidase activity
OOM_RS02655	COG0076	glutamate decarboxylase activity
OOM_RS02675	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OOM_RS02685	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OOM_RS02695	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
OOM_RS02705	COG1034	ATP synthesis coupled electron transport
OOM_RS02710	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OOM_RS02715	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OOM_RS02720	COG0839	Belongs to the complex I subunit 6 family
OOM_RS02725	COG0713	ATP synthesis coupled electron transport
OOM_RS02755	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OOM_RS02765	COG0779	Required for maturation of 30S ribosomal subunits
OOM_RS02770	COG0195	Participates in both transcription termination and antitermination
OOM_RS02770	COG2251	uridine kinase activity
OOM_RS02775	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OOM_RS02780	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OOM_RS02785	COG0124	histidyl-tRNA synthetase
OOM_RS02795	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OOM_RS02800	COG0564	pseudouridine synthase activity
OOM_RS02825	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OOM_RS02830	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OOM_RS02835	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OOM_RS02840	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OOM_RS02845	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OOM_RS02850	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OOM_RS02860	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OOM_RS02865	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OOM_RS02875	COG2223	nitrite transmembrane transporter activity
OOM_RS02885	COG2009	succinate dehydrogenase
OOM_RS02890	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OOM_RS02895	COG1053	succinate dehydrogenase
OOM_RS02900	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OOM_RS02915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OOM_RS02920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OOM_RS02925	COG0149	triose-phosphate isomerase activity
OOM_RS02930	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OOM_RS02955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OOM_RS02995	COG1294	oxidase, subunit
OOM_RS03010	COG1090	epimerase
OOM_RS03015	COG0642	Histidine kinase
OOM_RS03040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OOM_RS03045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OOM_RS03065	COG1663	tetraacyldisaccharide 4'-kinase activity
OOM_RS03070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OOM_RS03070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OOM_RS03080	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
OOM_RS03085	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OOM_RS03090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OOM_RS03100	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OOM_RS03115	COG0552	protein localization to endoplasmic reticulum
OOM_RS03120	COG0210	DNA helicase
OOM_RS03145	COG2814	Major facilitator Superfamily
OOM_RS03160	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OOM_RS03165	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OOM_RS03170	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OOM_RS03205	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OOM_RS03215	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OOM_RS03225	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OOM_RS03230	COG0081	regulation of translation
OOM_RS03235	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OOM_RS03240	COG0222	ribosome binding
OOM_RS03245	COG0085	RNA polymerase activity
OOM_RS03250	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OOM_RS03260	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OOM_RS03270	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OOM_RS03275	COG0228	four-way junction DNA binding
OOM_RS03280	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OOM_RS03285	COG0336	Belongs to the RNA methyltransferase TrmD family
OOM_RS03290	COG0335	large ribosomal subunit rRNA binding
OOM_RS03295	COG4974	Belongs to the 'phage' integrase family
OOM_RS03330	COG0494	nUDIX hydrolase
OOM_RS03350	COG0814	amino acid
OOM_RS03360	COG2814	Major facilitator Superfamily
OOM_RS03365	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OOM_RS03375	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OOM_RS03380	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OOM_RS03385	COG2890	protein-(glutamine-N5) methyltransferase activity
OOM_RS03390	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OOM_RS03395	COG3022	response to hydroperoxide
OOM_RS03435	COG0463	Glycosyl transferase, family 2
OOM_RS03455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OOM_RS03460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OOM_RS03475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OOM_RS03485	COG1028	Short-chain dehydrogenase reductase Sdr
OOM_RS03490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OOM_RS03505	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OOM_RS03510	COG1918	ferrous iron import across plasma membrane
OOM_RS03525	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OOM_RS03530	COG0459	protein refolding
OOM_RS03540	COG0300	oxidoreductase activity
OOM_RS03560	COG2081	HI0933 family
OOM_RS03570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OOM_RS03585	COG0531	amino acid
OOM_RS03600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OOM_RS03625	COG0814	amino acid
OOM_RS03635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OOM_RS03655	COG0742	ribosomal rna small subunit methyltransferase
OOM_RS03660	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OOM_RS03665	COG0814	amino acid
OOM_RS03675	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OOM_RS03680	COG0825	malonyl-CoA metabolic process
OOM_RS03700	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OOM_RS03725	COG0180	Tryptophanyl-tRNA synthetase
OOM_RS03745	COG0237	dephospho-CoA kinase activity
OOM_RS03760	COG0508	dehydrogenase complex catalyzes the overall conversion of
OOM_RS03765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OOM_RS03775	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OOM_RS03825	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OOM_RS03830	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OOM_RS03835	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OOM_RS03885	COG1183	phosphatidylcholine synthase activity
OOM_RS03890	COG0142	geranyltranstransferase activity
OOM_RS03895	COG1519	Transferase
OOM_RS03900	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OOM_RS03905	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OOM_RS03910	COG0745	RESPONSE REGULATOR receiver
OOM_RS03915	COG0681	Belongs to the peptidase S26 family
OOM_RS03920	COG0571	ribonuclease III activity
OOM_RS03930	COG0557	exoribonuclease II activity
OOM_RS03940	COG1028	Short-chain dehydrogenase reductase Sdr
OOM_RS03985	COG0500	methyltransferase
OOM_RS04015	COG0010	Belongs to the arginase family
OOM_RS04040	COG0183	Belongs to the thiolase family
OOM_RS04045	COG1024	Enoyl-CoA hydratase
OOM_RS04045	COG1250	3-hydroxyacyl-CoA dehydrogenase
OOM_RS04050	COG1960	acyl-CoA dehydrogenase activity
OOM_RS04055	COG0318	PFAM AMP-dependent synthetase and ligase
OOM_RS04075	COG1086	Polysaccharide biosynthesis protein
OOM_RS04080	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OOM_RS04095	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
OOM_RS04100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OOM_RS04120	COG1088	dTDP-glucose 4,6-dehydratase activity
OOM_RS04135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OOM_RS04155	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OOM_RS04200	COG1028	Short-chain dehydrogenase reductase Sdr
OOM_RS04245	COG1216	Glycosyl transferase, family 2
OOM_RS04245	COG1442	glycosyl transferase family 8
OOM_RS04255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OOM_RS04255	COG2755	lipolytic protein G-D-S-L family
OOM_RS04265	COG1682	transport, permease protein
OOM_RS04275	COG1216	Glycosyl transferase, family 2
OOM_RS04315	COG0248	Ppx GppA phosphatase
OOM_RS04320	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OOM_RS04340	COG0084	hydrolase, TatD family'
OOM_RS04355	COG3264	Mechanosensitive ion channel
OOM_RS04355	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
OOM_RS04370	COG0730	response to heat
OOM_RS04380	COG1131	(ABC) transporter
OOM_RS04385	COG0842	Transport permease protein
OOM_RS04390	COG0463	Glycosyl transferase, family 2
OOM_RS04405	COG1280	lysine exporter protein (LysE YggA)
OOM_RS04410	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OOM_RS04430	COG0640	Transcriptional regulator
OOM_RS04465	COG2983	Belongs to the UPF0260 family
OOM_RS04490	COG0436	Aminotransferase
OOM_RS04505	COG0442	prolyl-tRNA aminoacylation
OOM_RS04520	COG2166	iron-sulfur cluster assembly
OOM_RS04540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OOM_RS04585	COG0069	glutamate synthase activity
OOM_RS04590	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OOM_RS04615	COG1074	ATP-dependent DNA helicase activity
OOM_RS04620	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OOM_RS04635	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OOM_RS04650	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OOM_RS04665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OOM_RS04665	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OOM_RS04670	COG0483	inositol monophosphate 1-phosphatase activity
OOM_RS04675	COG2855	membrane
OOM_RS04695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OOM_RS04700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OOM_RS04705	COG1028	Short-chain dehydrogenase reductase Sdr
OOM_RS04710	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OOM_RS04720	COG0416	fatty acid biosynthetic process
OOM_RS04725	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OOM_RS04730	COG1399	metal-binding, possibly nucleic acid-binding protein
OOM_RS04750	COG0469	pyruvate kinase activity
OOM_RS04755	COG0191	fructose-bisphosphate aldolase activity
OOM_RS04860	COG3655	Transcriptional regulator
OOM_RS04870	COG2255	four-way junction helicase activity
OOM_RS04885	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OOM_RS04890	COG0519	Catalyzes the synthesis of GMP from XMP
OOM_RS04890	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OOM_RS04895	COG0101	tRNA pseudouridine synthase activity
OOM_RS04910	COG1137	ATPase activity
OOM_RS04925	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OOM_RS04930	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OOM_RS04935	COG1686	Belongs to the peptidase S11 family
OOM_RS04940	COG2921	Belongs to the UPF0250 family
OOM_RS04965	COG1610	YqeY-like protein
OOM_RS04975	COG2027	D-alanyl-D-alanine carboxypeptidase
OOM_RS04990	COG0037	tRNA processing
OOM_RS05000	COG0142	geranyltranstransferase activity
OOM_RS05025	COG1187	pseudouridine synthase activity
OOM_RS05035	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OOM_RS05045	COG0359	binds to the 23S rRNA
OOM_RS05050	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OOM_RS05055	COG0360	Binds together with S18 to 16S ribosomal RNA
OOM_RS05060	COG2996	Protein conserved in bacteria
OOM_RS05065	COG0210	DNA helicase
OOM_RS05070	COG0354	folic acid binding
OOM_RS05085	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OOM_RS05095	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OOM_RS05105	COG0210	DNA helicase
OOM_RS05135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OOM_RS05150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OOM_RS05215	COG0386	Belongs to the glutathione peroxidase family
OOM_RS05240	COG0583	DNA-binding transcription factor activity
OOM_RS05270	COG1876	peptidase activity
OOM_RS05300	COG0450	alkyl hydroperoxide reductase
OOM_RS05315	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OOM_RS05325	COG1994	Peptidase M50
OOM_RS05335	COG0688	phosphatidylethanolamine metabolic process
OOM_RS05345	COG1056	cytidyltransferase-related domain
OOM_RS05345	COG1051	belongs to the nudix hydrolase family
OOM_RS05350	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OOM_RS05355	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OOM_RS05380	COG0024	Methionine aminopeptidase
OOM_RS05395	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OOM_RS05405	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
OOM_RS05420	COG0668	transmembrane transport
OOM_RS05425	COG0587	DNA-directed DNA polymerase activity
OOM_RS05465	COG1982	Orn Lys Arg decarboxylase major
OOM_RS05470	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OOM_RS05480	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OOM_RS05515	COG1523	belongs to the glycosyl hydrolase 13 family
OOM_RS05520	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OOM_RS05525	COG0033	Phosphoglucomutase
OOM_RS05530	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OOM_RS05535	COG0297	glycogen (starch) synthase activity
OOM_RS05540	COG0058	SHG alpha-glucan phosphorylase activity
OOM_RS05545	COG1640	4-alpha-glucanotransferase
OOM_RS05560	COG0752	glycyl-tRNA synthetase alpha subunit
OOM_RS05575	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OOM_RS05585	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OOM_RS05590	COG0460	homoserine dehydrogenase
OOM_RS05590	COG0527	aspartate kinase activity
OOM_RS05600	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OOM_RS05615	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OOM_RS05620	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OOM_RS05645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OOM_RS05650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OOM_RS05690	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OOM_RS05695	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OOM_RS05705	COG0772	Belongs to the SEDS family
OOM_RS05715	COG0463	Glycosyl transferase, family 2
OOM_RS05725	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
OOM_RS05735	COG0625	glutathione transferase activity
OOM_RS05740	COG0616	signal peptide processing
OOM_RS05745	COG0470	DNA polymerase III
OOM_RS05755	COG0113	porphobilinogen synthase activity
OOM_RS05760	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OOM_RS05795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OOM_RS05800	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OOM_RS05805	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OOM_RS05810	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OOM_RS05820	COG0439	Biotin carboxylase
OOM_RS05830	COG0668	transmembrane transport
OOM_RS05840	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OOM_RS05840	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OOM_RS05845	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OOM_RS05855	COG0531	amino acid
OOM_RS05885	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OOM_RS05900	COG0492	ferredoxin-NADP+ reductase activity
OOM_RS05965	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OOM_RS05970	COG0045	succinate-CoA ligase (ADP-forming) activity
OOM_RS05985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OOM_RS06000	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OOM_RS06005	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OOM_RS06010	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OOM_RS06015	COG0318	PFAM AMP-dependent synthetase and ligase
OOM_RS06015	COG0204	Acyl-transferase
OOM_RS06020	COG0275	rRNA processing
OOM_RS06025	COG3116	cell division
OOM_RS06035	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OOM_RS06040	COG1185	polyribonucleotide nucleotidyltransferase activity
OOM_RS06045	COG0316	Belongs to the HesB IscA family
OOM_RS06050	COG2877	3-deoxy-8-phosphooctulonate synthase activity
OOM_RS06055	COG0572	uridine kinase
OOM_RS06060	COG1758	RNA polymerase activity
OOM_RS06115	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OOM_RS06120	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OOM_RS06125	COG0814	amino acid
OOM_RS06135	COG0156	8-amino-7-oxononanoate synthase activity
OOM_RS06140	COG0534	Mate efflux family protein
OOM_RS06150	COG0477	Major facilitator Superfamily
OOM_RS06155	COG0232	Belongs to the dGTPase family. Type 2 subfamily
OOM_RS06160	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
OOM_RS06170	COG2271	Major facilitator Superfamily
OOM_RS06175	COG0584	glycerophosphoryl diester phosphodiesterase
OOM_RS06190	COG1131	(ABC) transporter
OOM_RS06205	COG0251	oxidation-reduction process
OOM_RS06230	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OOM_RS06235	COG4988	ABC transporter
OOM_RS06260	COG1940	carbohydrate kinase activity
OOM_RS06285	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OOM_RS06290	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OOM_RS06295	COG0277	FAD linked oxidase domain protein
OOM_RS06295	COG0247	lactate metabolic process
OOM_RS06310	COG0295	cytidine deaminase activity
OOM_RS06315	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
OOM_RS06325	COG2860	membrane
OOM_RS06330	COG0742	ribosomal rna small subunit methyltransferase
OOM_RS06340	COG0612	Peptidase, M16
OOM_RS06345	COG0795	lipopolysaccharide-transporting ATPase activity
OOM_RS06350	COG0795	lipopolysaccharide-transporting ATPase activity
OOM_RS06355	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OOM_RS06360	COG0517	IMP dehydrogenase activity
OOM_RS06360	COG0516	GMP reductase activity
OOM_RS06370	COG0166	Belongs to the GPI family
OOM_RS06380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OOM_RS06385	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OOM_RS06395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OOM_RS06400	COG0813	purine-nucleoside phosphorylase activity
OOM_RS06415	COG0653	protein targeting
OOM_RS06420	COG0519	Catalyzes the synthesis of GMP from XMP
OOM_RS06425	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OOM_RS06430	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OOM_RS06440	COG1177	transmembrane transport
OOM_RS06445	COG1176	ABC-type spermidine putrescine transport system, permease component I
OOM_RS06450	COG3842	ATPase activity
OOM_RS06485	COG3104	oligopeptide transport
OOM_RS06490	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OOM_RS06495	COG0531	amino acid
OOM_RS06500	COG1605	Chorismate mutase
OOM_RS06500	COG0077	Prephenate dehydratase
OOM_RS06515	COG1760	l-serine dehydratase
OOM_RS06520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OOM_RS06525	COG0316	Belongs to the HesB IscA family
OOM_RS06530	COG2151	metal-sulfur cluster biosynthetic enzyme
OOM_RS06535	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OOM_RS06540	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OOM_RS06565	COG1058	Belongs to the CinA family
OOM_RS06565	COG1546	Belongs to the CinA family
OOM_RS06570	COG0189	ligase activity
OOM_RS06570	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OOM_RS06575	COG1181	Belongs to the D-alanine--D-alanine ligase family
OOM_RS06575	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OOM_RS06580	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OOM_RS06585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OOM_RS06590	COG0814	amino acid
OOM_RS06595	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OOM_RS06600	COG0343	queuine tRNA-ribosyltransferase activity
OOM_RS06615	COG1335	isochorismatase
OOM_RS06635	COG1862	Preprotein translocase
OOM_RS06640	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OOM_RS06645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OOM_RS06655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OOM_RS06670	COG0328	RNA-DNA hybrid ribonuclease activity
OOM_RS06675	COG0252	asparaginase activity
OOM_RS06680	COG0288	reversible hydration of carbon dioxide
OOM_RS06700	COG0740	serine-type endopeptidase activity
OOM_RS06705	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OOM_RS06710	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OOM_RS06725	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OOM_RS06730	COG1923	regulation of RNA biosynthetic process
OOM_RS06735	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OOM_RS06745	COG0330	HflC and HflK could
OOM_RS06750	COG0330	HflC and HflK could
OOM_RS06755	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OOM_RS06760	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OOM_RS06785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OOM_RS06815	COG0670	Belongs to the BI1 family
OOM_RS06830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OOM_RS06835	COG2878	Part of a membrane complex involved in electron transport
OOM_RS06840	COG2999	glutathione oxidoreductase activity
OOM_RS06850	COG1528	Iron-storage protein
OOM_RS06855	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OOM_RS06860	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
OOM_RS06865	COG0217	transcriptional regulatory protein
OOM_RS06870	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OOM_RS06875	COG2271	Major facilitator Superfamily
OOM_RS06885	COG1322	Protein conserved in bacteria
OOM_RS06930	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OOM_RS06935	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OOM_RS06940	COG4536	flavin adenine dinucleotide binding
OOM_RS06955	COG0193	aminoacyl-tRNA hydrolase activity
OOM_RS06970	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OOM_RS06980	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OOM_RS06990	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OOM_RS06995	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OOM_RS07005	COG0095	Lipoate-protein ligase
OOM_RS07010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OOM_RS07025	COG2301	Belongs to the HpcH HpaI aldolase family
OOM_RS07035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OOM_RS07050	COG1566	PFAM secretion protein HlyD family protein
OOM_RS07065	COG1509	lysine 2,3-aminomutase activity
OOM_RS07075	COG1278	Cold shock
OOM_RS07100	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OOM_RS07105	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OOM_RS07110	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OOM_RS07145	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OOM_RS07150	COG0084	hydrolase, TatD family'
OOM_RS07155	COG0751	glycine-tRNA ligase activity
OOM_RS07165	COG2814	Major facilitator Superfamily
OOM_RS07195	COG0301	tRNA thio-modification
OOM_RS07205	COG2835	tetraacyldisaccharide 4'-kinase activity
OOM_RS07210	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OOM_RS07240	COG2814	Major facilitator Superfamily
OOM_RS07250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OOM_RS07255	COG0513	Belongs to the DEAD box helicase family
OOM_RS07265	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OOM_RS07275	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OOM_RS07290	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OOM_RS07295	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OOM_RS07300	COG0408	coproporphyrinogen oxidase activity
OOM_RS07420	COG3321	synthase
OOM_RS07420	COG4221	oxidoreductase activity
OOM_RS07420	COG1028	Short-chain dehydrogenase reductase Sdr
OOM_RS07420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OOM_RS07475	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OOM_RS07475	COG0116	Belongs to the methyltransferase superfamily
OOM_RS07480	COG2076	Multidrug Resistance protein
OOM_RS07495	COG0640	Transcriptional regulator
OOM_RS07505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OOM_RS07510	COG0189	ligase activity
OOM_RS07515	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OOM_RS07530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OOM_RS07530	COG1017	nitric oxide dioxygenase activity
OOM_RS07535	COG1472	Belongs to the glycosyl hydrolase 3 family
OOM_RS07555	COG1940	carbohydrate kinase activity
OOM_RS07580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OOM_RS07580	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OOM_RS07595	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OOM_RS07595	COG0512	Glutamine amidotransferase of anthranilate synthase
OOM_RS07600	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OOM_RS07600	COG0512	Glutamine amidotransferase of anthranilate synthase
OOM_RS07640	COG3104	oligopeptide transport
OOM_RS07650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OOM_RS07670	COG0708	Exodeoxyribonuclease III
OOM_RS07690	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OOM_RS07695	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OOM_RS07705	COG0730	response to heat
OOM_RS07720	COG0531	amino acid
OOM_RS07725	COG0569	domain protein
OOM_RS07735	COG0719	Fe-S assembly protein
OOM_RS07740	COG0396	ATPase activity
OOM_RS07745	COG0719	Fe-S assembly protein
OOM_RS07755	COG3118	belongs to the thioredoxin family
OOM_RS07765	COG0833	amino acid
OOM_RS07780	COG0494	nUDIX hydrolase
OOM_RS07785	COG1678	Uncharacterized ACR, COG1678
OOM_RS07790	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OOM_RS07795	COG0495	leucyl-tRNA aminoacylation
OOM_RS07805	COG0668	transmembrane transport
OOM_RS07810	COG0717	Belongs to the dCTP deaminase family
OOM_RS07815	COG0489	protein tyrosine kinase activity
OOM_RS07830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OOM_RS07850	COG0735	belongs to the Fur family
OOM_RS07865	COG0730	response to heat
OOM_RS07870	COG0072	phenylalanine-tRNA ligase activity
OOM_RS07870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OOM_RS07875	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OOM_RS07895	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OOM_RS07900	COG3028	Belongs to the UPF0307 family
OOM_RS07930	COG3104	oligopeptide transport
OOM_RS07935	COG0037	tRNA processing
OOM_RS07940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OOM_RS07945	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OOM_RS07950	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OOM_RS07955	COG1530	ribonuclease E activity
OOM_RS07960	COG1104	cysteine desulfurase activity
OOM_RS07970	COG1381	Involved in DNA repair and RecF pathway recombination
OOM_RS07975	COG0586	Pfam SNARE associated Golgi protein
OOM_RS07980	COG0586	Pfam SNARE associated Golgi protein
OOM_RS07995	COG3079	Belongs to the UPF0149 family
OOM_RS08000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OOM_RS08005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OOM_RS08020	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OOM_RS08045	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OOM_RS08050	COG0346	lactoylglutathione lyase activity
OOM_RS08070	COG1611	Belongs to the LOG family
OOM_RS08090	COG3220	belongs to the UPF0276 family
OOM_RS08105	COG0517	IMP dehydrogenase activity
OOM_RS08105	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OOM_RS08110	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OOM_RS08120	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OOM_RS08140	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OOM_RS08150	COG1083	cytidylyl-transferase
OOM_RS08175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OOM_RS08205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OOM_RS08215	COG1446	asparaginase
OOM_RS08265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OOM_RS08270	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OOM_RS08275	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OOM_RS08280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OOM_RS08285	COG0509	glycine decarboxylation via glycine cleavage system
OOM_RS08300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OOM_RS08315	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OOM_RS08340	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
OOM_RS08355	COG0445	tRNA wobble uridine modification
OOM_RS08375	COG4221	oxidoreductase activity
OOM_RS08380	COG2925	Exonuclease
OOM_RS08385	COG0556	nucleotide-excision repair
OOM_RS08400	COG0477	Major facilitator Superfamily
OOM_RS08435	COG1570	exodeoxyribonuclease VII activity
OOM_RS08470	COG0140	phosphoribosyl-ATP diphosphatase activity
OOM_RS08470	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OOM_RS08480	COG0076	glutamate decarboxylase activity
OOM_RS08490	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OOM_RS08495	COG2867	negative regulation of translational initiation
OOM_RS08500	COG2914	Belongs to the UPF0125 (RnfH) family
OOM_RS08505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OOM_RS08505	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
OOM_RS08515	COG0405	Gamma-glutamyltransferase
OOM_RS08550	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OOM_RS08565	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OOM_RS08570	COG1823	symporter activity
OOM_RS08575	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OOM_RS08580	COG2814	Major facilitator Superfamily
OOM_RS08630	COG0815	Transfers the fatty acyl group on membrane lipoproteins
OOM_RS08635	COG4535	Mg2 and Co2 transporter CorC
OOM_RS08640	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OOM_RS08650	COG1702	phosphate starvation-inducible protein PhoH
OOM_RS08655	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OOM_RS08660	COG4122	O-methyltransferase activity
OOM_RS08675	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OOM_RS08685	COG1214	PFAM Peptidase M22, glycoprotease
OOM_RS08695	COG0436	Aminotransferase
OOM_RS08700	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OOM_RS08705	COG0277	FAD linked oxidase domain protein
OOM_RS08710	COG0563	adenylate kinase activity
OOM_RS08740	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OOM_RS08760	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OOM_RS08775	COG2814	Major facilitator Superfamily
OOM_RS08780	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OOM_RS08795	COG0415	Belongs to the DNA photolyase family
OOM_RS08820	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OOM_RS08860	COG0488	(ABC) transporter
OOM_RS08875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OOM_RS08880	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OOM_RS08890	COG0039	L-malate dehydrogenase activity
OOM_RS08900	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
OOM_RS08920	COG2814	Major facilitator Superfamily
OOM_RS08925	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OOM_RS08930	COG4178	(ABC) transporter
OOM_RS08935	COG0531	amino acid
OOM_RS08940	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OOM_RS08945	COG0814	amino acid
OOM_RS08965	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
OOM_RS08970	COG1733	regulation of RNA biosynthetic process
OOM_RS08985	COG2271	Major facilitator Superfamily
OOM_RS09025	COG0084	hydrolase, TatD family'
OOM_RS09030	COG3201	nicotinamide mononucleotide transporter
OOM_RS09075	COG0542	response to heat
OOM_RS09100	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OOM_RS09110	COG0204	Acyl-transferase
OOM_RS09135	COG0545	Peptidyl-prolyl cis-trans isomerase
OOM_RS09155	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OOM_RS09205	COG0488	(ABC) transporter
OOM_RS09265	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OOM_RS09275	COG0512	Glutamine amidotransferase of anthranilate synthase
OOM_RS09400	COG2132	Multicopper oxidase
OOM_RS09595	COG3104	oligopeptide transport
OOM_RS09600	COG3104	oligopeptide transport
OOM_RS09605	COG0402	S-adenosylhomocysteine deaminase activity
OOM_RS09660	COG0653	protein targeting
OOM_RS09755	COG2089	acid synthase
OOM_RS09765	COG3525	Glycosyl hydrolase, family 20, catalytic domain
OOM_RS09785	COG0745	RESPONSE REGULATOR receiver
OOM_RS09800	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OOM_RS09860	COG0270	DNA (cytosine-5-)-methyltransferase activity
OOM_RS09985	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane