locus-tag	class	description
F7308_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
F7308_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
F7308_RS00020	ENOG4107QTZ	amino acid
F7308_RS00060	ENOG4105BZU	Histidine kinase
F7308_RS00075	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
F7308_RS00090	ENOG4105C44	Serine transporter
F7308_RS00095	ENOG4105CXT	aspartate transcarbamylase
F7308_RS00100	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
F7308_RS00120	ENOG4105CD3	dihydroorotase
F7308_RS00125	ENOG4107U2T	alpha beta
F7308_RS00140	ENOG4107V40	secretion protein, HlyD family
F7308_RS00150	ENOG4105SKE	transcriptional Regulator LysR family
F7308_RS00170	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
F7308_RS00185	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
F7308_RS00190	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
F7308_RS00210	ENOG4107R3K	hydrolase
F7308_RS00215	ENOG4105DUX	Transporter
F7308_RS00220	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
F7308_RS00225	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
F7308_RS00230	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
F7308_RS00235	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
F7308_RS00240	ENOG4105CM2	brancheD-chain amino acid aminotransferase
F7308_RS00250	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
F7308_RS00260	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
F7308_RS00270	ENOG4105D1S	lipid A biosynthesis
F7308_RS00275	ENOG4105D1S	lipid A biosynthesis
F7308_RS00280	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
F7308_RS00285	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
F7308_RS00300	ENOG4105E2X	shikimate dehydrogenase
F7308_RS00305	ENOG4105DFU	Cell wall formation (By similarity)
F7308_RS00310	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
F7308_RS00335	ENOG41081QV	Universal stress protein
F7308_RS00340	ENOG4105CSH	Transporter
F7308_RS00355	ENOG4107R7A	Allophanate hydrolase subunit 2
F7308_RS00360	ENOG4105DIJ	Phosphoethanolamine transferase
F7308_RS00365	ENOG41080IJ	Diacylglycerol kinase
F7308_RS00380	ENOG4105HSS	phospholipase C
F7308_RS00395	ENOG4105CPW	cytochrome b561
F7308_RS00415	ENOG4105E0U	tyrosine-specific transport protein
F7308_RS00420	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
F7308_RS00425	ENOG4105DFA	alanine racemase domain protein
F7308_RS00435	ENOG4105JQN	Transcriptional regulator
F7308_RS00440	ENOG4105C2C	drug resistance transporter, Bcr CflA
F7308_RS00445	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
F7308_RS00450	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
F7308_RS00465	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
F7308_RS00475	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
F7308_RS00485	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
F7308_RS00495	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
F7308_RS00500	ENOG4108R6K	riboflavin synthase, subunit alpha
F7308_RS00505	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
F7308_RS00510	ENOG4105EEQ	Na H antiporter
F7308_RS00515	ENOG4107RA9	decarboxylase
F7308_RS00535	ENOG4107YZP	Rhodanese domain protein
F7308_RS00545	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
F7308_RS00550	ENOG410691R	Modulates RecA activity (By similarity)
F7308_RS00555	ENOG4108UUM	single-stranded DNA-binding protein
F7308_RS00565	ENOG4105C6K	Malic enzyme
F7308_RS00570	ENOG4105C26	Dehydrogenase
F7308_RS00590	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
F7308_RS00600	ENOG4105C9M	aspartyl-trna synthetase
F7308_RS00605	ENOG4108ST3	glycosyltransferase
F7308_RS00620	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
F7308_RS00625	ENOG4107PI4	Protein CrcB homolog
F7308_RS00645	ENOG4105F38	ABC transporter, permease
F7308_RS00680	ENOG4108Z0R	Transferase
F7308_RS00690	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
F7308_RS00705	ENOG4108VIA	integral membrane protein
F7308_RS00715	ENOG4105F38	ABC transporter, permease
F7308_RS00720	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
F7308_RS00725	ENOG4106HNH	Acyl-transferase
F7308_RS00735	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
F7308_RS00740	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
F7308_RS00745	ENOG4108Z6B	deaminase
F7308_RS00750	ENOG4105CPF	Cell wall formation (By similarity)
F7308_RS00755	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
F7308_RS00760	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
F7308_RS00765	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
F7308_RS00780	ENOG4107QMP	dna polymerase iii subunits gamma and tau
F7308_RS00785	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
F7308_RS00790	ENOG4105CRK	lysyL-tRNA synthetase
F7308_RS00800	ENOG4108TEB	UPF0114 protein
F7308_RS00805	ENOG4105CSV	Glutaminase
F7308_RS00810	ENOG4107R5B	glutamine synthetase
F7308_RS00820	ENOG4105QNF	Outer membrane lipoprotein
F7308_RS00825	ENOG4105C44	Serine transporter
F7308_RS00830	ENOG4105DC1	bifunctional purine biosynthesis protein purh
F7308_RS00835	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
F7308_RS00855	ENOG4108JJB	ABC transporter
F7308_RS00865	ENOG4108SC4	)-transporter
F7308_RS00875	ENOG4105CS1	NAD(P)H quinone oxidoreductase
F7308_RS00880	ENOG4107S2Z	UPF0761 membrane protein
F7308_RS00890	ENOG4105C25	Primosomal protein n'
F7308_RS00900	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
F7308_RS00905	ENOG4105C4M	(Ubiquinol oxidase) subunit I
F7308_RS00910	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F7308_RS00920	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
F7308_RS00930	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
F7308_RS00950	ENOG4107QVM	von Willebrand factor, type A
F7308_RS00965	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
F7308_RS00985	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
F7308_RS00990	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
F7308_RS01010	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
F7308_RS01030	ENOG4108RCM	Nitroreductase
F7308_RS01040	ENOG4105C9Q	fumarate hydratase class II
F7308_RS01045	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
F7308_RS01070	ENOG4105D7W	serine acetyltransferase
F7308_RS01080	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
F7308_RS01085	ENOG4105CE9	30S ribosomal protein S2
F7308_RS01090	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
F7308_RS01100	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
F7308_RS01105	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
F7308_RS01110	ENOG4105KNE	Phosphatidate cytidylyltransferase
F7308_RS01115	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
F7308_RS01120	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
F7308_RS01130	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
F7308_RS01135	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
F7308_RS01140	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
F7308_RS01145	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
F7308_RS01150	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
F7308_RS01155	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
F7308_RS01160	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
F7308_RS01165	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
F7308_RS01170	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
F7308_RS01180	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
F7308_RS01200	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
F7308_RS01210	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
F7308_RS01215	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
F7308_RS01220	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
F7308_RS01225	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
F7308_RS01235	ENOG4105VPB	50S ribosomal protein L30
F7308_RS01240	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
F7308_RS01245	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
F7308_RS01255	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F7308_RS01265	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
F7308_RS01280	ENOG4105EYW	Ion transport protein
F7308_RS01285	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
F7308_RS01290	ENOG4105DBV	ornithine carbamoyltransferase
F7308_RS01295	ENOG4105CAS	nag kinase
F7308_RS01300	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
F7308_RS01315	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
F7308_RS01320	ENOG4105CH7	arginosuccinase
F7308_RS01325	ENOG4105CDH	Citrulline--aspartate ligase
F7308_RS01330	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
F7308_RS01345	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
F7308_RS01350	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
F7308_RS01355	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
F7308_RS01360	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
F7308_RS01365	ENOG4105K8N	protein family UPF0079, ATPase
F7308_RS01375	ENOG4105CJR	Integral membrane protein (MviN
F7308_RS01380	ENOG4105D9M	gamma-glutamylcysteine synthetase
F7308_RS01415	ENOG4105W7K	Transcriptional regulator
F7308_RS01475	ENOG4105CVR	type I restriction-modification system
F7308_RS01485	ENOG4105EKX	Restriction modification system DNA (Specificity
F7308_RS01490	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
F7308_RS01500	ENOG4105DZR	Type I site-specific deoxyribonuclease
F7308_RS01510	ENOG4108YYH	Nadph-dependent fmn reductase
F7308_RS01515	ENOG4108UXE	Protein tyrosine phosphatase
F7308_RS01525	ENOG4105D6J	arsenicaL-resistance protein
F7308_RS01550	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
F7308_RS01570	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
F7308_RS01575	ENOG4105CNU	cell division protein FtsK
F7308_RS01585	ENOG4108IQI	permease
F7308_RS01590	ENOG4105DHZ	alpha beta
F7308_RS01595	ENOG4105CBT	Fructose-1,6-bisphosphatase
F7308_RS01600	ENOG4105CK7	Sodium proline symporter
F7308_RS01610	ENOG4105C37	(CBS) domain
F7308_RS01655	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
F7308_RS01660	ENOG4107QNK	)-transporter
F7308_RS01665	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
F7308_RS01685	ENOG4107QTZ	amino acid
F7308_RS01700	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
F7308_RS01710	ENOG4105DWY	Agmatine deiminase
F7308_RS01730	ENOG4107PE3	Mammalian cell entry related domain protein
F7308_RS01735	ENOG4105CY3	ABC transporter, permease
F7308_RS01740	ENOG4105DHJ	ABC, transporter
F7308_RS01750	ENOG4107QMS	site-determining protein
F7308_RS01755	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
F7308_RS01760	ENOG4105W0E	50S ribosomal protein L33
F7308_RS01765	ENOG4105KDC	50s ribosomal protein l28
F7308_RS01775	ENOG4105CB5	ATP-dependent DNA helicase recG
F7308_RS01785	ENOG4107GFK	fumarate
F7308_RS01800	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
F7308_RS01810	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
F7308_RS01825	ENOG4105C7N	Xanthine uracil vitamin C permease
F7308_RS01835	ENOG4105D0C	transport protein
F7308_RS01840	ENOG4105C79	DNA protecting protein DprA
F7308_RS01855	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
F7308_RS01860	ENOG4105KHN	chorismate mutase
F7308_RS01865	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
F7308_RS01875	ENOG4105E02	MotA TolQ exbB proton channel
F7308_RS01880	ENOG4105M8F	Biopolymer transport protein exbD tolR
F7308_RS01900	ENOG4105UYK	outer membrane protein a
F7308_RS01905	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
F7308_RS01920	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
F7308_RS01925	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
F7308_RS01930	ENOG4105C09	Bile acid
F7308_RS01935	ENOG4108SGR	YheO domain-containing protein
F7308_RS01965	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
F7308_RS01975	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
F7308_RS01995	ENOG4105D0M	Protease HtpX homolog
F7308_RS02000	ENOG4108V0P	LemA family
F7308_RS02005	ENOG4105DUM	transcriptional regulator, lysR family
F7308_RS02025	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
F7308_RS02035	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
F7308_RS02065	ENOG4105E0X	reductase
F7308_RS02080	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
F7308_RS02085	ENOG4107QPD	alcohol dehydrogenase
F7308_RS02090	ENOG4105CHM	Aminotransferase
F7308_RS02095	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
F7308_RS02110	ENOG4105KHS	type IV fimbrial pilin protein
F7308_RS02115	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
F7308_RS02120	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
F7308_RS02125	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
F7308_RS02130	ENOG4105C8V	SAICAR synthetase
F7308_RS02135	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
F7308_RS02140	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
F7308_RS02145	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
F7308_RS02150	ENOG41082RQ	UPF0102 protein
F7308_RS02155	ENOG4105DGW	oligopeptidase A
F7308_RS02195	ENOG4107QJE	Chromosome Partitioning Protein
F7308_RS02200	ENOG4105FA0	parb-like partition protein
F7308_RS02205	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
F7308_RS02215	ENOG4105R1U	AraC Family Transcriptional Regulator
F7308_RS02220	ENOG4105DJ2	Major Facilitator Superfamily
F7308_RS02225	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
F7308_RS02240	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
F7308_RS02245	ENOG4105DTN	riboflavin biosynthesis protein ribF
F7308_RS02250	ENOG4105C6K	Malic enzyme
F7308_RS02265	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
F7308_RS02270	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
F7308_RS02275	ENOG4105D4A	Cell wall formation (By similarity)
F7308_RS02285	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
F7308_RS02290	ENOG4105MJ2	Competence protein
F7308_RS02295	ENOG4107YU2	histidine triad (hIT) protein
F7308_RS02300	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
F7308_RS02310	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
F7308_RS02315	ENOG4105CHC	glucokinase (EC 2.7.1.2)
F7308_RS02325	ENOG4107835	probably involved in intracellular septation (By similarity)
F7308_RS02330	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
F7308_RS02335	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
F7308_RS02340	ENOG4108I5G	Major Facilitator superfamily
F7308_RS02385	ENOG4105CXY	transporter
F7308_RS02395	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
F7308_RS02400	ENOG4105KVH	Transcriptional regulator
F7308_RS02405	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
F7308_RS02415	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
F7308_RS02420	ENOG4105C08	Histidine kinase
F7308_RS02435	ENOG4105E0U	tyrosine-specific transport protein
F7308_RS02440	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
F7308_RS02445	ENOG4105C0X	amino acid
F7308_RS02450	ENOG4105CQ0	ABC transporter
F7308_RS02470	ENOG4105CFP	Peptidase U32
F7308_RS02485	ENOG4105ETT	transcriptional Regulator, LysR family
F7308_RS02495	ENOG4105DFG	type I secretion outer membrane protein
F7308_RS02510	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
F7308_RS02515	ENOG4108ETH	Formylglycinamide ribotide synthetase
F7308_RS02540	ENOG4105C83	adenylosuccinate lyase
F7308_RS02555	ENOG4106FEW	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
F7308_RS02560	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
F7308_RS02585	ENOG4105EYM	Major Facilitator superfamily
F7308_RS02610	ENOG4105DY8	decarboxylase
F7308_RS02620	ENOG4105CFH	Aspartokinase
F7308_RS02625	ENOG41090R7	Ferric uptake
F7308_RS02630	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
F7308_RS02640	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
F7308_RS02645	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
F7308_RS02655	ENOG4107QIZ	NADH dehydrogenase
F7308_RS02660	ENOG4108IEH	NADH dehydrogenase subunit g
F7308_RS02665	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
F7308_RS02670	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
F7308_RS02675	ENOG4105DF2	NADH dehydrogenase subunit j
F7308_RS02690	ENOG4105C8S	subunit m
F7308_RS02700	ENOG4105W0Z	cytoplasmic protein
F7308_RS02705	ENOG4105C0P	Mg chelatase subunit ChlI
F7308_RS02710	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
F7308_RS02720	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
F7308_RS02725	ENOG4105CHV	Transcription elongation factor NusA
F7308_RS02735	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
F7308_RS02740	ENOG4108IUR	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
F7308_RS02750	ENOG4105D6Z	AFG1 family ATPase
F7308_RS02755	ENOG4105EI2	Pseudouridine synthase
F7308_RS02780	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
F7308_RS02785	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
F7308_RS02790	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
F7308_RS02800	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
F7308_RS02805	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
F7308_RS02815	ENOG4105M2J	Glutaredoxin
F7308_RS02820	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
F7308_RS02830	ENOG4105EYM	Major Facilitator superfamily
F7308_RS02835	ENOG4105BZN	citrate synthase
F7308_RS02840	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
F7308_RS02845	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
F7308_RS02850	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
F7308_RS02855	ENOG4105E33	succinate dehydrogenase
F7308_RS02860	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
F7308_RS02865	ENOG4105C7S	Dehydrogenase
F7308_RS02870	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
F7308_RS02875	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
F7308_RS02880	ENOG4105CP7	Triose-phosphate isomerase
F7308_RS02885	ENOG4105NTZ	Preprotein translocase subunit SecG
F7308_RS02895	ENOG4105DFP	Integrase
F7308_RS02955	ENOG4105CSA	Coproporphyrinogen iii oxidase
F7308_RS02970	ENOG4108I0Z	Aconitate hydratase
F7308_RS02975	ENOG4105CZX	twitching motility protein
F7308_RS02990	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
F7308_RS02995	ENOG4105C4M	(Ubiquinol oxidase) subunit I
F7308_RS03000	ENOG4105ECP	epimerase
F7308_RS03005	ENOG4105DHQ	Histidine kinase
F7308_RS03030	ENOG4105BZS	acriflavin resistance protein
F7308_RS03035	ENOG410624X	efflux transporter, rnd family, mfp subunit
F7308_RS03050	ENOG4105BZ1	(ABC) transporter
F7308_RS03055	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
F7308_RS03060	ENOG4105C2M	dna polymerase I
F7308_RS03070	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
F7308_RS03075	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
F7308_RS03080	ENOG4105D9N	nucleoside
F7308_RS03085	ENOG4105D9N	nucleoside
F7308_RS03090	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
F7308_RS03095	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
F7308_RS03105	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
F7308_RS03110	ENOG4105C4R	Atp-dependent dna helicase
F7308_RS03130	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
F7308_RS03140	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
F7308_RS03155	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
F7308_RS03185	ENOG4105PM1	preprotein translocase subunit SecE
F7308_RS03190	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
F7308_RS03195	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
F7308_RS03200	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
F7308_RS03205	ENOG4108VZM	50s ribosomal protein L10
F7308_RS03215	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
F7308_RS03220	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
F7308_RS03230	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
F7308_RS03240	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
F7308_RS03250	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
F7308_RS03255	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
F7308_RS03260	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
F7308_RS03265	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
F7308_RS03290	ENOG4105EMU	Dehydrogenase
F7308_RS03300	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
F7308_RS03315	ENOG4105CEM	UPF0597 protein
F7308_RS03325	ENOG4105C2C	drug resistance transporter, Bcr CflA
F7308_RS03330	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
F7308_RS03340	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
F7308_RS03345	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
F7308_RS03350	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
F7308_RS03355	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
F7308_RS03360	ENOG4105D1Q	UPF0246 protein
F7308_RS03395	ENOG4105CKK	Glycosyl transferase, family 2
F7308_RS03420	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
F7308_RS03435	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
F7308_RS03445	ENOG4105C2D	reductase
F7308_RS03450	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
F7308_RS03465	ENOG4105CE1	Ferrous iron transport protein b
F7308_RS03470	ENOG4105XFK	Ferrous iron transport protein A
F7308_RS03490	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
F7308_RS03495	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
F7308_RS03505	ENOG4105E1F	short-chain dehydrogenase reductase
F7308_RS03510	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
F7308_RS03525	ENOG4105CBX	hi0933 family
F7308_RS03535	ENOG4105D82	Glutamate dehydrogenase
F7308_RS03550	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
F7308_RS03555	ENOG4105E5D	amino acid
F7308_RS03560	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
F7308_RS03565	ENOG4108RSN	SNARE associated Golgi
F7308_RS03605	ENOG4105CIC	tryptophan-specific transport protein
F7308_RS03615	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
F7308_RS03635	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
F7308_RS03640	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
F7308_RS03645	ENOG4105E0U	tyrosine-specific transport protein
F7308_RS03655	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
F7308_RS03660	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
F7308_RS03680	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
F7308_RS03690	ENOG4105EEQ	Na H antiporter
F7308_RS03700	ENOG4105C31	Tryptophanyl-tRNA synthetase
F7308_RS03720	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
F7308_RS03730	ENOG4108JA1	polyketide synthase
F7308_RS03735	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
F7308_RS03745	ENOG41084CK	capsule polysaccharide
F7308_RS03750	ENOG4107FW0	short-chain dehydrogenase reductase
F7308_RS03755	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F7308_RS03760	ENOG4105E12	capsule polysaccharide
F7308_RS03765	ENOG4107V1M	polysaccharide export protein
F7308_RS03805	ENOG4107V1M	polysaccharide export protein
F7308_RS03815	ENOG4107S6X	Glycosyl transferase, family 2
F7308_RS03820	ENOG4107QQG	Dehydrogenase
F7308_RS03840	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
F7308_RS03900	ENOG4105E12	capsule polysaccharide
F7308_RS03910	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
F7308_RS03920	ENOG4107QN2	dihydrolipoyl dehydrogenase
F7308_RS03925	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
F7308_RS03940	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F7308_RS03950	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F7308_RS03965	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
F7308_RS03970	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F7308_RS03975	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F7308_RS03990	ENOG4105CSR	polyphosphate kinase 2
F7308_RS03995	ENOG4105VE1	Phosphatidylcholine synthase
F7308_RS04000	ENOG4105CTB	Polyprenyl synthetase
F7308_RS04005	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
F7308_RS04010	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
F7308_RS04015	ENOG4105II7	pyrroline-5-carboxylate reductase
F7308_RS04020	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
F7308_RS04025	ENOG4105C3F	Signal peptidase i
F7308_RS04030	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
F7308_RS04035	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
F7308_RS04040	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
F7308_RS04065	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
F7308_RS04080	ENOG4105GR3	Histidine kinase
F7308_RS04100	ENOG4108WF3	methyltransferase
F7308_RS04130	ENOG4105CYW	agmatinase
F7308_RS04145	ENOG4107QNK	)-transporter
F7308_RS04155	ENOG4105CHU	acetyl-coa acetyltransferase
F7308_RS04165	ENOG4107QPN	acyl-Coa dehydrogenase
F7308_RS04170	ENOG4105CEY	Amp-dependent synthetase and ligase
F7308_RS04175	ENOG4105K89	arsenate reductase
F7308_RS04180	ENOG4105E9K	Isocitrate dehydrogenase
F7308_RS04185	ENOG4105CQ7	ATP-dependent helicase
F7308_RS04190	ENOG4105C5E	polysaccharide biosynthesis protein
F7308_RS04210	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
F7308_RS04215	ENOG4105C30	Nad-dependent epimerase dehydratase
F7308_RS04220	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
F7308_RS04225	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
F7308_RS04235	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
F7308_RS04245	ENOG4108UT6	Transferase hexapeptide repeat containing protein
F7308_RS04260	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
F7308_RS04280	ENOG4105CKK	Glycosyl transferase, family 2
F7308_RS04300	ENOG4108T5R	
F7308_RS04325	ENOG4105W2C	Glycosyl transferase
F7308_RS04330	ENOG4105W2C	Glycosyl transferase
F7308_RS04345	ENOG4105EXC	Acyl-transferase
F7308_RS04355	ENOG4105EY8	ABC transporter
F7308_RS04360	ENOG4105ECJ	Glycosyl Transferase
F7308_RS04370	ENOG4107TYR	Glycosyl Transferase
F7308_RS04390	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
F7308_RS04395	ENOG4105K63	Thioredoxin
F7308_RS04400	ENOG4105C9X	ppx gppa phosphatase
F7308_RS04405	ENOG4105D1H	recombination factor protein RarA
F7308_RS04515	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
F7308_RS04525	ENOG4105F8V	Hydrolase, tatD family
F7308_RS04530	ENOG4105EGS	Mechanosensitive ion channel
F7308_RS04545	ENOG4105EJ9	Membrane
F7308_RS04555	ENOG4105DA5	(ABC) transporter
F7308_RS04560	ENOG4105E3A	(ABC) transporter
F7308_RS04575	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
F7308_RS04580	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
F7308_RS04595	ENOG4105CE4	GlcNAc 6-P deacetylase
F7308_RS04600	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
F7308_RS04610	ENOG41080HT	Transcriptional regulator, arsr family
F7308_RS04615	ENOG4108V62	Rhodanese domain protein
F7308_RS04620	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
F7308_RS04645	ENOG4108ZZ3	UPF0260 protein
F7308_RS04655	ENOG4107YIM	Involved in the transcription termination process (By similarity)
F7308_RS04670	ENOG4105CHM	Aminotransferase
F7308_RS04675	ENOG4105EXC	Acyl-transferase
F7308_RS04685	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
F7308_RS04700	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
F7308_RS04720	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
F7308_RS04750	ENOG4105SBG	acid phosphatase
F7308_RS04770	ENOG4105CBC	glutamate synthase
F7308_RS04775	ENOG4105DSY	exodeoxyribonuclease V, gamma
F7308_RS04785	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
F7308_RS04800	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
F7308_RS04815	ENOG4107QKA	exodeoxyribonuclease V beta
F7308_RS04820	ENOG4107QYX	exodeoxyribonuclease v alpha
F7308_RS04825	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
F7308_RS04830	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
F7308_RS04835	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
F7308_RS04850	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
F7308_RS04870	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
F7308_RS04880	ENOG4105HMI	Membrane
F7308_RS04890	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
F7308_RS04900	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
F7308_RS04905	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
F7308_RS04910	ENOG4105CHR	reductase
F7308_RS04915	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
F7308_RS04925	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
F7308_RS04930	ENOG4105VGS	50s ribosomal protein l32
F7308_RS04935	ENOG4105KNH	Nucleic acid-binding protein
F7308_RS04940	ENOG4105CV1	Transketolase (EC 2.2.1.1)
F7308_RS04950	ENOG4105BZA	Phosphoglycerate kinase
F7308_RS04955	ENOG4105CA9	Pyruvate kinase
F7308_RS04960	ENOG4105D2N	Aldolase
F7308_RS04965	ENOG4105E53	ec 3.2.1.28
F7308_RS05085	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
F7308_RS05100	ENOG4105GZI	Transcriptional regulator
F7308_RS05110	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
F7308_RS05120	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
F7308_RS05130	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
F7308_RS05135	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
F7308_RS05175	ENOG4108UJD	30S ribosomal protein S9
F7308_RS05180	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
F7308_RS05195	ENOG4105CA3	membrane-bound lytic murein transglycosylase
F7308_RS05200	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F7308_RS05205	ENOG4105CFG	Acts as a chaperone (By similarity)
F7308_RS05210	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
F7308_RS05220	ENOG4105C4K	Nad synthetase
F7308_RS05230	ENOG4105CW7	secretion protein, HlyD family
F7308_RS05235	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
F7308_RS05245	ENOG4105CEY	Amp-dependent synthetase and ligase
F7308_RS05255	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
F7308_RS05275	ENOG4105DHJ	ABC, transporter
F7308_RS05290	ENOG4105C34	Pseudouridine synthase
F7308_RS05295	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F7308_RS05300	ENOG4105DNP	FAD linked oxidase domain protein
F7308_RS05300	ENOG4105DNP	FAD linked oxidase domain protein
F7308_RS05305	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
F7308_RS05310	ENOG4105N42	UPF0307 protein
F7308_RS05340	ENOG4105DUX	Transporter
F7308_RS05345	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
F7308_RS05350	ENOG4108JQ1	Dehydrogenase
F7308_RS05355	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
F7308_RS05360	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
F7308_RS05365	ENOG4105C03	ribonuclease
F7308_RS05385	ENOG4105DQR	SNARE associated Golgi
F7308_RS05390	ENOG4105DQR	SNARE associated Golgi
F7308_RS05405	ENOG4105E07	UPF0149 protein
F7308_RS05415	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
F7308_RS05420	ENOG4105SBG	acid phosphatase
F7308_RS05430	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
F7308_RS05440	ENOG4108X4Q	Hydrolase
F7308_RS05465	ENOG4108UYE	Lactoylglutathione lyase
F7308_RS05475	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
F7308_RS05485	ENOG4108URH	decarboxylase
F7308_RS05490	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
F7308_RS05505	ENOG4105E18	UPF0276 protein
F7308_RS05520	ENOG4105C2X	Arabinose 5-phosphate isomerase
F7308_RS05525	ENOG4105DJV	ribulose-phosphate 3-epimerase
F7308_RS05545	ENOG4105CMR	udp-glucose 4-epimerase
F7308_RS05555	ENOG4105BZ1	(ABC) transporter
F7308_RS05590	ENOG4105DE4	1-phosphofructokinase
F7308_RS05630	ENOG4105CSH	Transporter
F7308_RS05650	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
F7308_RS05655	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
F7308_RS05660	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
F7308_RS05665	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
F7308_RS05670	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
F7308_RS05680	ENOG4108M1A	Chitin-binding protein
F7308_RS05685	ENOG4105C22	threonyL-tRNA synthetase
F7308_RS05690	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
F7308_RS05695	ENOG41082NX	50s ribosomal protein l35
F7308_RS05715	ENOG4105E66	phosphoriboisomerase A
F7308_RS05730	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
F7308_RS05750	ENOG4105EMU	Dehydrogenase
F7308_RS05755	ENOG4105CJB	Exodeoxyribonuclease I
F7308_RS05765	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
F7308_RS05780	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
F7308_RS05800	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
F7308_RS05805	ENOG4105D06	uba thif-type nad fad binding protein
F7308_RS05810	ENOG4105CSH	Transporter
F7308_RS05815	ENOG4105CSH	Transporter
F7308_RS05855	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
F7308_RS05885	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
F7308_RS05890	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
F7308_RS05895	ENOG4105CIH	Imidazole acetol-phosphate transaminase
F7308_RS05900	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
F7308_RS05910	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
F7308_RS05915	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
F7308_RS05920	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
F7308_RS05930	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
F7308_RS05935	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
F7308_RS05940	ENOG4108Z1B	Cyclase dehydrase
F7308_RS05945	ENOG4105VDB	UPF0125 protein
F7308_RS05955	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
F7308_RS05960	ENOG410903C	(LipO)protein
F7308_RS05965	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
F7308_RS05970	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
F7308_RS05985	ENOG4105K6H	D-cysteine desulfhydrase
F7308_RS05990	ENOG4105VCQ	rubredoxin
F7308_RS06000	ENOG4105CNG	UPF0061 protein
F7308_RS06010	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
F7308_RS06015	ENOG4107QNK	)-transporter
F7308_RS06020	ENOG4105E2D	ec 3.2.1.52
F7308_RS06025	ENOG4107QNR	UPF0135 protein
F7308_RS06035	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
F7308_RS06070	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
F7308_RS06075	ENOG4108JU5	Magnesium and cobalt efflux protein
F7308_RS06080	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
F7308_RS06085	ENOG4105C9A	Phoh family
F7308_RS06090	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
F7308_RS06095	ENOG4108VQJ	O-methyltransferase
F7308_RS06105	ENOG4107104	thymidine kinase
F7308_RS06115	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
F7308_RS06120	ENOG41072GX	Peptidase M22 Glycoprotease
F7308_RS06130	ENOG4105CHM	Aminotransferase
F7308_RS06135	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
F7308_RS06145	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
F7308_RS06155	ENOG4105CQB	FAD linked oxidase domain protein
F7308_RS06160	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
F7308_RS06185	ENOG4105E4G	Type IV pilus
F7308_RS06190	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
F7308_RS06210	ENOG4107KD5	Flavinator of succinate dehydrogenase
F7308_RS06215	ENOG4105C26	Dehydrogenase
F7308_RS06220	ENOG4107QTZ	amino acid
F7308_RS06225	ENOG4107RGD	Major Facilitator superfamily
F7308_RS06230	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
F7308_RS06235	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
F7308_RS06245	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
F7308_RS06265	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
F7308_RS06270	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
F7308_RS06300	ENOG4105C5H	ABC transporter
F7308_RS06305	ENOG4107QNK	)-transporter
F7308_RS06320	ENOG41090BQ	Glutaredoxin
F7308_RS06330	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
F7308_RS06340	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
F7308_RS06350	ENOG4105CUZ	uba thif-type nad fad binding protein
F7308_RS06365	ENOG4105D3R	alkyl hydroperoxide reductase
F7308_RS06375	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
F7308_RS06390	ENOG4108JDX	DNA polymerase iii, epsilon subunit
F7308_RS06395	ENOG4108VXD	carboxy-peptidase
F7308_RS06410	ENOG4105C26	Dehydrogenase
F7308_RS06420	ENOG4105C5Q	Transcriptional regulator
F7308_RS06435	ENOG4105CH6	catalase
F7308_RS06450	ENOG4105CAT	Cytidine monophosphate kinase
F7308_RS06455	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
F7308_RS06460	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
F7308_RS06465	ENOG4105C72	UPF0176 protein
F7308_RS06490	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
F7308_RS06495	ENOG4105KPY	Small multidrug resistance protein
F7308_RS06500	ENOG4105D6J	arsenicaL-resistance protein
F7308_RS06505	ENOG41082YX	Transcriptional regulator, arsr family
F7308_RS06515	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
F7308_RS06520	ENOG4105D7Z	glutathione synthase
F7308_RS06525	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
F7308_RS06530	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
F7308_RS06535	ENOG4105KPV	Transcriptional regulator
F7308_RS06540	ENOG4108DEF	Globin
F7308_RS06545	ENOG4105D17	glycoside hydrolase, family 3 domain protein
F7308_RS06570	ENOG4105E2R	ROK family
F7308_RS06575	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
F7308_RS06580	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
F7308_RS06585	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
F7308_RS06590	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
F7308_RS06595	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
F7308_RS06600	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
F7308_RS06615	ENOG4105EEI	dihydropteroate synthase
F7308_RS06625	ENOG4105CEY	Amp-dependent synthetase and ligase
F7308_RS06635	ENOG4105DDQ	anthranilate synthase
F7308_RS06645	ENOG4105CPC	Aldo Keto reductase
F7308_RS06650	ENOG4105CPC	Aldo Keto reductase
F7308_RS06670	ENOG4105EUJ	GTP cyclohydrolase i
F7308_RS06675	ENOG4105C1J	atp-dependent rna helicase
F7308_RS06680	ENOG4105DUX	Transporter
F7308_RS06685	ENOG41082CH	UPF0145 protein
F7308_RS06690	ENOG4105DC8	reductase
F7308_RS06710	ENOG4105CGK	Exodeoxyribonuclease III
F7308_RS06720	ENOG4105NF4	modulator of drug activity
F7308_RS06740	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
F7308_RS06745	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F7308_RS06770	ENOG4105E5D	amino acid
F7308_RS06775	ENOG4105C1A	potassium transporter peripheral membrane
F7308_RS06790	ENOG4105C3K	feS assembly ATPase SufC
F7308_RS06795	ENOG4105JRK	feS assembly protein SufD
F7308_RS06805	ENOG4105K63	Thioredoxin
F7308_RS06815	ENOG4108IQI	permease
F7308_RS06825	ENOG4105M6F	mutator MutT protein
F7308_RS06830	ENOG4108UJU	UPF0301 protein
F7308_RS06835	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
F7308_RS06840	ENOG4105C8T	Leucyl-tRNA synthetase
F7308_RS06850	ENOG4105CUY	Mechanosensitive ion channel
F7308_RS06855	ENOG4105DHP	deoxycytidine triphosphate deaminase
F7308_RS06870	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
F7308_RS06890	ENOG4105CKI	cobalamin synthesis protein
F7308_RS06895	ENOG4105MYN	Zinc uptake regulation protein
F7308_RS06910	ENOG4105HF0	Membrane
F7308_RS06915	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
F7308_RS06920	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
F7308_RS06925	ENOG4108TVT	permease
F7308_RS06930	ENOG4105DUX	Transporter
F7308_RS06935	ENOG4105CT4	transporter
F7308_RS06945	ENOG4105DEI	Mannitol dehydrogenase
F7308_RS06950	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
F7308_RS06955	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
F7308_RS06960	ENOG4108UHU	Aldolase
F7308_RS06970	ENOG4107QNK	)-transporter
F7308_RS07000	ENOG4105VMP	Transcriptional regulator
F7308_RS07010	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
F7308_RS07025	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
F7308_RS07030	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
F7308_RS07035	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
F7308_RS07040	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
F7308_RS07050	ENOG4108IUZ	ABC transporter
F7308_RS07065	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
F7308_RS07070	ENOG4105F0N	pyrophosphate phospho-hydrolase
F7308_RS07075	ENOG4105DZ1	carboxypeptidase
F7308_RS07080	ENOG4108Z43	UPF0250 protein
F7308_RS07100	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
F7308_RS07105	ENOG4105KTH	gatB Yqey
F7308_RS07110	ENOG4105VCC	30S ribosomal protein S21
F7308_RS07115	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
F7308_RS07130	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
F7308_RS07140	ENOG4105EAH	synthase
F7308_RS07165	ENOG4105FE9	pseudouridine synthase
F7308_RS07175	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
F7308_RS07180	ENOG4105CDU	Replicative dna helicase
F7308_RS07185	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
F7308_RS07190	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
F7308_RS07195	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
F7308_RS07200	ENOG4105QNR	S1 RNA binding domain protein
F7308_RS07215	ENOG4105C4R	Atp-dependent dna helicase
F7308_RS07220	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
F7308_RS07230	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
F7308_RS07235	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
F7308_RS07245	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
F7308_RS07255	ENOG4105C4R	Atp-dependent dna helicase
F7308_RS07285	ENOG4105C2C	drug resistance transporter, Bcr CflA
F7308_RS07290	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
F7308_RS07295	ENOG4105KAV	tspo and mbr like protein
F7308_RS07300	ENOG4105C94	Transporter
F7308_RS07315	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
F7308_RS07335	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
F7308_RS07350	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
F7308_RS07370	ENOG4105DTQ	mandelate racemase muconate lactonizing
F7308_RS07380	ENOG4108V06	Glutathione peroxidase
F7308_RS07395	ENOG4108IYU	L-aspartate oxidase
F7308_RS07400	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
F7308_RS07405	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
F7308_RS07415	ENOG4105C1J	atp-dependent rna helicase
F7308_RS07420	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
F7308_RS07425	ENOG4107QNK	)-transporter
F7308_RS07430	ENOG4107QNK	)-transporter
F7308_RS07435	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
F7308_RS07440	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
F7308_RS07460	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
F7308_RS07465	ENOG4105W49	UPF0434 protein
F7308_RS07475	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
F7308_RS07485	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
F7308_RS07495	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
F7308_RS07500	ENOG4105C2C	drug resistance transporter, Bcr CflA
F7308_RS07510	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
F7308_RS07515	ENOG4105EYA	deoxyribonuclease
F7308_RS07520	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
F7308_RS07545	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
F7308_RS07550	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
F7308_RS07585	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
F7308_RS07610	ENOG4105EWK	phytoene
F7308_RS07620	ENOG4105VEJ	Heat shock protein
F7308_RS07625	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
F7308_RS07630	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
F7308_RS07640	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
F7308_RS07645	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
F7308_RS07650	ENOG4105DUX	Transporter
F7308_RS07655	ENOG4107SVH	Potassium channel protein
F7308_RS07660	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
F7308_RS07680	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
F7308_RS07685	ENOG4105C3G	gtp-binding protein
F7308_RS07695	ENOG4108JU6	CBS domain protein
F7308_RS07700	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
F7308_RS07705	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
F7308_RS07720	ENOG4105D2S	major facilitator superfamily
F7308_RS07730	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
F7308_RS07750	ENOG4105CGY	Dna recombination protein
F7308_RS07770	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
F7308_RS07775	ENOG4105CDY	transcriptional regulatory protein
F7308_RS07780	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
F7308_RS07785	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
F7308_RS07790	ENOG41090A1	ferritin
F7308_RS07795	ENOG4105DUX	Transporter
F7308_RS07805	ENOG4105E9S	glutaredoxin 2
F7308_RS07810	ENOG4108R3D	Electron transport complex
F7308_RS07815	ENOG4105CSM	endonuclease III
F7308_RS07830	ENOG4108MN8	Membrane
F7308_RS07835	ENOG4108JA2	transcriptioN-repair coupling factor
F7308_RS07845	ENOG4105C7K	acetolactate synthase
F7308_RS07850	ENOG4105C01	Dihydroxy-acid dehydratase
F7308_RS07855	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
F7308_RS07860	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
F7308_RS07865	ENOG4105KJF	protein tyrosine phosphatase
F7308_RS07870	ENOG4105EPW	hflc protein
F7308_RS07885	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
F7308_RS07895	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
F7308_RS07905	ENOG4105K70	DNA-binding protein
F7308_RS07910	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
F7308_RS07915	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
F7308_RS07920	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
F7308_RS07925	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
F7308_RS07935	ENOG41077A9	carbonic anhydrase
F7308_RS07940	ENOG4105HDK	L-asparaginase
F7308_RS07945	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
F7308_RS07960	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F7308_RS07970	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
F7308_RS07975	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
F7308_RS07980	ENOG4105VIE	preprotein translocase, subunit YajC
F7308_RS07985	ENOG4108T88	
F7308_RS07995	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
F7308_RS08005	ENOG4105ETT	transcriptional Regulator, LysR family
F7308_RS08010	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
F7308_RS08015	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
F7308_RS08020	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
F7308_RS08025	ENOG4105D01	(LipO)protein
F7308_RS08030	ENOG4105E0U	tyrosine-specific transport protein
F7308_RS08035	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
F7308_RS08040	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
F7308_RS08045	ENOG4105D9M	gamma-glutamylcysteine synthetase
F7308_RS08050	ENOG4105D9M	gamma-glutamylcysteine synthetase
F7308_RS08065	ENOG4107QHF	type ii secretion system protein e
F7308_RS08075	ENOG4105CDV	Ompa motb domain protein
F7308_RS08080	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
F7308_RS08085	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
F7308_RS08090	ENOG4105VG1	fes assembly suf system protein
F7308_RS08095	ENOG4108Z4V	iron-sulfur cluster assembly
F7308_RS08100	ENOG4105C9B	Cysteine desulfurase
F7308_RS08105	ENOG4105EJQ	L-serine dehydratase
F7308_RS08115	ENOG4105CGH	5'-nucleotidase
F7308_RS08120	ENOG4105CQC	Prephenate dehydratase
F7308_RS08125	ENOG4107QTZ	amino acid
F7308_RS08130	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
F7308_RS08135	ENOG4105DUX	Transporter
F7308_RS08155	ENOG4105EAC	phosphoserine phosphatase
F7308_RS08180	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
F7308_RS08185	ENOG4105F38	ABC transporter, permease
F7308_RS08190	ENOG4105D38	putrescine abc transporter
F7308_RS08200	ENOG4105K46	50S ribosomal protein l27
F7308_RS08205	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
F7308_RS08210	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
F7308_RS08230	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
F7308_RS08235	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
F7308_RS08240	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
F7308_RS08245	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
F7308_RS08255	ENOG4107QP8	phosphohexose isomerase
F7308_RS08265	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
F7308_RS08280	ENOG4108M8S	permease YjgP YjgQ family protein
F7308_RS08285	ENOG4108K5H	permease YjgP YjgQ family protein
F7308_RS08300	ENOG4106H78	methyltransferase
F7308_RS08305	ENOG4105DUM	transcriptional regulator, lysR family
F7308_RS08310	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
F7308_RS08315	ENOG4105C26	Dehydrogenase
F7308_RS08320	ENOG4107QTZ	amino acid
F7308_RS08325	ENOG4105EN6	Membrane
F7308_RS08330	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
F7308_RS08335	ENOG4108I5U	Uridine phosphorylase
F7308_RS08340	ENOG4105KG3	cytidine deaminase
F7308_RS08345	ENOG4105DUX	Transporter
F7308_RS08360	ENOG4105CQB	FAD linked oxidase domain protein
F7308_RS08365	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
F7308_RS08370	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
F7308_RS08385	ENOG4105EVU	fructokinase
F7308_RS08410	ENOG4108JJ9	ABC, transporter
F7308_RS08415	ENOG4108JJ8	(ABC) transporter
F7308_RS08430	ENOG4105KME	endoribonuclease L-psp
F7308_RS08435	ENOG4105CHH	sulfate transporter
F7308_RS08440	ENOG4107QWP	ABC-2 type transporter
F7308_RS08445	ENOG4105CJ1	ABC, transporter
F7308_RS08455	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
F7308_RS08460	ENOG4105CXY	transporter
F7308_RS08470	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
F7308_RS08505	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
F7308_RS08510	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
F7308_RS08515	ENOG4105CSH	Transporter
F7308_RS08525	ENOG4107R73	Mate efflux family protein
F7308_RS08535	ENOG4105CIY	formyltetrahydrofolate deformylase
F7308_RS08540	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
F7308_RS08550	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
F7308_RS08555	ENOG4105CPQ	Dehydrogenase
F7308_RS08560	ENOG4105C44	Serine transporter
F7308_RS08565	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
F7308_RS08570	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
F7308_RS08585	ENOG4107XDY	Nicotinamide Mononucleotide Transporter
F7308_RS08595	ENOG4105DKQ	ROK family
F7308_RS08615	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
F7308_RS08620	ENOG4105DBI	uridine monophosphokinase
F7308_RS08625	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
F7308_RS08630	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
F7308_RS08635	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
F7308_RS08640	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
F7308_RS08645	ENOG4105CJN	penicillin-binding protein
F7308_RS08655	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
F7308_RS08660	ENOG4105CEY	Amp-dependent synthetase and ligase
F7308_RS08665	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
F7308_RS08670	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
F7308_RS08675	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
F7308_RS08680	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F7308_RS08710	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
F7308_RS08715	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
F7308_RS08725	ENOG4105E1F	short-chain dehydrogenase reductase
F7308_RS08730	ENOG4105IPI	Membrane
F7308_RS08740	ENOG4105DUX	Transporter
F7308_RS08760	ENOG4106N3A	copper homeostasis protein cutc
F7308_RS08765	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
F7308_RS08770	ENOG4105C3M	thioredoxin reductase
F7308_RS08785	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
F7308_RS08800	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
F7308_RS08805	ENOG4108HM4	ABC transporter
F7308_RS08810	ENOG4105E5D	amino acid
F7308_RS08820	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
F7308_RS08825	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
F7308_RS08830	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
F7308_RS08835	ENOG4105D64	Mechanosensitive ion channel
F7308_RS08845	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
F7308_RS08850	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
F7308_RS08855	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
F7308_RS08860	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
F7308_RS08865	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
F7308_RS08870	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
F7308_RS08885	ENOG4105DUX	Transporter
F7308_RS08890	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
F7308_RS08900	ENOG4105HBR	Rna-binding protein
F7308_RS08905	ENOG4107QRG	dna polymerase iii
F7308_RS08910	ENOG4105ERU	peptidase
F7308_RS08915	ENOG4107MKT	Stringent starvation protein a
F7308_RS08920	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
F7308_RS08925	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
F7308_RS08930	ENOG4105CNI	cell division protein FtsW
F7308_RS08935	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
F7308_RS08940	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
F7308_RS08950	ENOG4105CX6	glutaminyL-tRNA synthetase
F7308_RS08955	ENOG4105DUX	Transporter
F7308_RS08960	ENOG4105C5H	ABC transporter
F7308_RS08975	ENOG4105C2N	RNA methyltransferase TrmH family group 3
F7308_RS08980	ENOG4105DFU	Cell wall formation (By similarity)
F7308_RS08985	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
F7308_RS08995	ENOG4105D98	threonine synthase
F7308_RS09005	ENOG4105CFH	Aspartokinase
F7308_RS09010	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
F7308_RS09020	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
F7308_RS09035	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
F7308_RS09040	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
F7308_RS09055	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
F7308_RS09060	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
F7308_RS09065	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
F7308_RS09070	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
F7308_RS09075	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
F7308_RS09080	ENOG4108IUM	Glycogen debranching enzyme
F7308_RS09110	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F7308_RS09115	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F7308_RS09125	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
F7308_RS09130	ENOG4105CXN	decarboxylase
F7308_RS09150	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
F7308_RS09155	ENOG4105EXC	Acyl-transferase
F7308_RS09170	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
F7308_RS09170	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
F7308_RS09185	ENOG4105C0B	DNA polymerase III (alpha subunit)
F7308_RS09190	ENOG4105D64	Mechanosensitive ion channel
F7308_RS09205	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
F7308_RS09215	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
F7308_RS09220	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F7308_RS09230	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
F7308_RS09235	ENOG4105EMY	transcriptional regulator
F7308_RS09240	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
F7308_RS09250	ENOG4105VEQ	Cold shock protein
F7308_RS09265	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
F7308_RS09270	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
F7308_RS09285	ENOG4105DJ4	phosphatidylserine decarboxylase
F7308_RS09295	ENOG4108Z4T	Peptidase M50
F7308_RS09335	ENOG4105CHM	Aminotransferase
F7308_RS09345	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
F7308_RS09350	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
F7308_RS09355	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
F7308_RS09360	ENOG4105CFH	Aspartokinase
F7308_RS09395	ENOG4105CMQ	Chloride channel
F7308_RS09560	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
F7308_RS09565	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
F7308_RS09575	ENOG4107XDY	Nicotinamide Mononucleotide Transporter
F7308_RS09585	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
F7308_RS09615	ENOG4108Z4U	Ferredoxin
F7308_RS09625	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
F7308_RS09660	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
F7308_RS09665	ENOG4107RSS	Hydrogenase accessory protein HypB
F7308_RS09690	ENOG4105CQS	hydrogenase expression formation protein HypD
F7308_RS09720	ENOG4105D9G	High-affinity
F7308_RS09730	ENOG4105D52	delta-aminolevulinic acid dehydratase
F7308_RS09750	ENOG4105C5H	ABC transporter
F7308_RS09775	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
F7308_RS09795	ENOG4108RVA	ribokinase
F7308_RS09800	ENOG4105CD8	aminopeptidase N
F7308_RS09805	ENOG4105DK0	Indole-3-glycerol phosphate synthase
F7308_RS09825	ENOG4108I0Q	anthranilate phosphoribosyltransferase
F7308_RS09830	ENOG4105DDQ	anthranilate synthase
F7308_RS09835	ENOG4105CRQ	synthase (Component I)
F7308_RS09855	ENOG4105C03	ribonuclease
F7308_RS09880	ENOG4105SBG	acid phosphatase
F7308_RS09890	ENOG4105VTR	Integrase
F7308_RS09895	ENOG4108M1A	Chitin-binding protein
F7308_RS09900	ENOG4105K64	Glycosyl transferase, family 2
F7308_RS09915	ENOG4108W5M	transcriptional regulator
F7308_RS09920	ENOG4105CC0	LysR family Transcriptional regulator
F7308_RS09935	ENOG4105C2C	drug resistance transporter, Bcr CflA
F7308_RS09975	ENOG4108M1A	Chitin-binding protein
F7308_RS10050	ENOG4107TXC	Transcriptional regulator
