locus-tag	class	description
QI37_RS00005	COG4948	Mandelate Racemase Muconate Lactonizing
QI37_RS00050	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
QI37_RS00065	COG4536	flavin adenine dinucleotide binding
QI37_RS00085	COG0193	aminoacyl-tRNA hydrolase activity
QI37_RS00100	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
QI37_RS00105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
QI37_RS00110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
QI37_RS00115	COG3104	oligopeptide transport
QI37_RS00125	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
QI37_RS00135	COG0814	amino acid
QI37_RS00145	COG0095	Lipoate-protein ligase
QI37_RS00150	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
QI37_RS00155	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
QI37_RS00175	COG0582	viral genome integration into host DNA
QI37_RS00255	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
QI37_RS00275	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
QI37_RS00280	COG1210	Utp--glucose-1-phosphate uridylyltransferase
QI37_RS00285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
QI37_RS00295	COG0815	Transfers the fatty acyl group on membrane lipoproteins
QI37_RS00300	COG4535	Mg2 and Co2 transporter CorC
QI37_RS00305	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
QI37_RS00310	COG1702	phosphate starvation-inducible protein PhoH
QI37_RS00315	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
QI37_RS00320	COG4122	O-methyltransferase activity
QI37_RS00335	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
QI37_RS00340	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
QI37_RS00345	COG1214	PFAM Peptidase M22, glycoprotease
QI37_RS00355	COG0436	Aminotransferase
QI37_RS00360	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
QI37_RS00380	COG1649	PFAM Uncharacterised BCR, COG1649
QI37_RS00425	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
QI37_RS00440	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
QI37_RS00460	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
QI37_RS00465	COG0415	Belongs to the DNA photolyase family
QI37_RS00480	COG2264	protein methyltransferase activity
QI37_RS00490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
QI37_RS00495	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
QI37_RS00505	COG0488	(ABC) transporter
QI37_RS00520	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
QI37_RS00540	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
QI37_RS00550	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
QI37_RS00570	COG0450	alkyl hydroperoxide reductase
QI37_RS00580	COG2824	Alkylphosphonate utilization operon protein PhnA
QI37_RS00600	COG1876	peptidase activity
QI37_RS00620	COG1012	belongs to the aldehyde dehydrogenase family
QI37_RS00630	COG1937	Protein conserved in bacteria
QI37_RS00640	COG2132	Multicopper oxidase
QI37_RS00645	COG0583	DNA-binding transcription factor activity
QI37_RS00660	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
QI37_RS00665	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
QI37_RS00675	COG0360	Binds together with S18 to 16S ribosomal RNA
QI37_RS00680	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
QI37_RS00685	COG0359	binds to the 23S rRNA
QI37_RS00705	COG1187	pseudouridine synthase activity
QI37_RS00730	COG0142	geranyltranstransferase activity
QI37_RS00740	COG0037	tRNA processing
QI37_RS00755	COG2027	D-alanyl-D-alanine carboxypeptidase
QI37_RS00765	COG1610	YqeY-like protein
QI37_RS00770	COG0358	DNA primase activity
QI37_RS00780	COG1252	NADH dehydrogenase
QI37_RS00795	COG1028	Short-chain dehydrogenase reductase Sdr
QI37_RS00820	COG2921	Belongs to the UPF0250 family
QI37_RS00825	COG1686	Belongs to the peptidase S11 family
QI37_RS00830	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
QI37_RS00835	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
QI37_RS00850	COG1137	ATPase activity
QI37_RS00860	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
QI37_RS00865	COG0101	tRNA pseudouridine synthase activity
QI37_RS00880	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
QI37_RS00895	COG1028	Short-chain dehydrogenase reductase Sdr
QI37_RS00900	COG2255	four-way junction helicase activity
QI37_RS00915	COG1937	Protein conserved in bacteria
QI37_RS00935	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
QI37_RS00945	COG1904	glucuronate isomerase
QI37_RS00950	COG0800	Aldolase
QI37_RS00955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
QI37_RS00965	COG0246	Mannitol dehydrogenase
QI37_RS00975	COG2211	Major facilitator Superfamily
QI37_RS00990	COG3104	oligopeptide transport
QI37_RS00995	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
QI37_RS01000	COG0072	phenylalanine-tRNA ligase activity
QI37_RS01000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
QI37_RS01015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
QI37_RS01025	COG0477	Major facilitator Superfamily
QI37_RS01040	COG0668	transmembrane transport
QI37_RS01050	COG0495	leucyl-tRNA aminoacylation
QI37_RS01055	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
QI37_RS01060	COG1678	Uncharacterized ACR, COG1678
QI37_RS01065	COG0494	nUDIX hydrolase
QI37_RS01080	COG1472	Belongs to the glycosyl hydrolase 3 family
QI37_RS01085	COG0833	amino acid
QI37_RS01115	COG0719	Fe-S assembly protein
QI37_RS01120	COG0396	ATPase activity
QI37_RS01125	COG0719	Fe-S assembly protein
QI37_RS01130	COG1959	2 iron, 2 sulfur cluster binding
QI37_RS01135	COG0569	domain protein
QI37_RS01140	COG0531	amino acid
QI37_RS01165	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
QI37_RS01170	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
QI37_RS01180	COG2249	NAD(P)H dehydrogenase (quinone) activity
QI37_RS01190	COG3104	oligopeptide transport
QI37_RS01195	COG0708	Exodeoxyribonuclease III
QI37_RS01215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
QI37_RS01230	COG0513	Belongs to the DEAD box helicase family
QI37_RS01235	COG0302	gtp cyclohydrolase
QI37_RS01245	COG1979	alcohol dehydrogenase
QI37_RS01255	COG0667	Aldo Keto reductase
QI37_RS01260	COG0667	Aldo Keto reductase
QI37_RS01275	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
QI37_RS01275	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
QI37_RS01280	COG0657	acetylesterase activity
QI37_RS01300	COG4689	acetoacetate decarboxylase
QI37_RS01310	COG1028	Short-chain dehydrogenase reductase Sdr
QI37_RS01315	COG1472	Belongs to the glycosyl hydrolase 3 family
QI37_RS01320	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
QI37_RS01325	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
QI37_RS01330	COG0189	ligase activity
QI37_RS01350	COG0116	Belongs to the methyltransferase superfamily
QI37_RS01350	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
QI37_RS01375	COG1278	Cold shock
QI37_RS01670	COG2974	May be involved in recombination
QI37_RS01685	COG2996	Protein conserved in bacteria
QI37_RS01700	COG0745	RESPONSE REGULATOR receiver
QI37_RS01740	COG0210	DNA helicase
QI37_RS01745	COG0354	folic acid binding
QI37_RS01755	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
QI37_RS01760	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
QI37_RS01770	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
QI37_RS01780	COG0210	DNA helicase
QI37_RS01790	COG0799	negative regulation of ribosome biogenesis
QI37_RS01810	COG2814	Major facilitator Superfamily
QI37_RS01820	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
QI37_RS01825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
QI37_RS01830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
QI37_RS01840	COG2988	succinylglutamate desuccinylase activity
QI37_RS01860	COG3240	lipase activity
QI37_RS01865	COG0535	radical SAM domain protein
QI37_RS01920	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
QI37_RS01920	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
QI37_RS01945	COG0386	Belongs to the glutathione peroxidase family
QI37_RS01955	COG0077	Prephenate dehydratase
QI37_RS01955	COG1605	Chorismate mutase
QI37_RS01970	COG0402	S-adenosylhomocysteine deaminase activity
QI37_RS01975	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
QI37_RS01985	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
QI37_RS01995	COG0513	Belongs to the DEAD box helicase family
QI37_RS02000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
QI37_RS02010	COG2814	Major facilitator Superfamily
QI37_RS02020	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
QI37_RS02025	COG2835	tetraacyldisaccharide 4'-kinase activity
QI37_RS02035	COG0482	sulfurtransferase activity
QI37_RS02055	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
QI37_RS02060	COG2814	Major facilitator Superfamily
QI37_RS02065	COG0751	glycine-tRNA ligase activity
QI37_RS02070	COG0084	hydrolase, TatD family'
QI37_RS02075	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
QI37_RS02125	COG1496	oxidoreductase activity
QI37_RS02140	COG2814	Major facilitator Superfamily
QI37_RS02145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
QI37_RS02165	COG1773	rubredoxin
QI37_RS02170	COG2515	1-aminocyclopropane-1-carboxylate deaminase
QI37_RS02190	COG1028	Short-chain dehydrogenase reductase Sdr
QI37_RS02200	COG0405	Gamma-glutamyltransferase
QI37_RS02205	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
QI37_RS02205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
QI37_RS02210	COG1943	Transposase
QI37_RS02215	COG2914	Belongs to the UPF0125 (RnfH) family
QI37_RS02220	COG2867	negative regulation of translational initiation
QI37_RS02225	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
QI37_RS02230	COG0037	tRNA processing
QI37_RS02235	COG4106	trans-aconitate 2-methyltransferase activity
QI37_RS02240	COG0477	Major facilitator Superfamily
QI37_RS02255	COG0795	lipopolysaccharide-transporting ATPase activity
QI37_RS02260	COG0795	lipopolysaccharide-transporting ATPase activity
QI37_RS02265	COG0612	Peptidase, M16
QI37_RS02275	COG0742	ribosomal rna small subunit methyltransferase
QI37_RS02280	COG2860	membrane
QI37_RS02295	COG1570	exodeoxyribonuclease VII activity
QI37_RS02310	COG0477	Major facilitator Superfamily
QI37_RS02315	COG0531	amino acid
QI37_RS02330	COG0556	nucleotide-excision repair
QI37_RS02335	COG2925	Exonuclease
QI37_RS02340	COG4221	oxidoreductase activity
QI37_RS02360	COG0445	tRNA wobble uridine modification
QI37_RS02375	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
QI37_RS02405	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
QI37_RS02420	COG0509	glycine decarboxylation via glycine cleavage system
QI37_RS02430	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
QI37_RS02440	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
QI37_RS02460	COG0477	Major facilitator Superfamily
QI37_RS02535	COG2856	Zn peptidase
QI37_RS02570	COG1446	asparaginase
QI37_RS02580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
QI37_RS02600	COG1442	glycosyl transferase family 8
QI37_RS02600	COG1216	Glycosyl transferase, family 2
QI37_RS02615	COG2244	polysaccharide biosynthetic process
QI37_RS02620	COG1216	Glycosyl transferase, family 2
QI37_RS02620	COG1442	glycosyl transferase family 8
QI37_RS02640	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
QI37_RS02645	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
QI37_RS02650	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
QI37_RS02655	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
QI37_RS02655	COG0517	IMP dehydrogenase activity
QI37_RS02670	COG3220	belongs to the UPF0276 family
QI37_RS02690	COG1611	Belongs to the LOG family
QI37_RS02705	COG0346	lactoylglutathione lyase activity
QI37_RS02710	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
QI37_RS02720	COG0561	phosphatase activity
QI37_RS02725	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
QI37_RS02730	COG2852	Protein conserved in bacteria
QI37_RS02745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
QI37_RS02755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
QI37_RS02760	COG3079	Belongs to the UPF0149 family
QI37_RS02795	COG0586	Pfam SNARE associated Golgi protein
QI37_RS02800	COG0586	Pfam SNARE associated Golgi protein
QI37_RS02815	COG1104	cysteine desulfurase activity
QI37_RS02820	COG1530	ribonuclease E activity
QI37_RS02830	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
QI37_RS02835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
QI37_RS02865	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
QI37_RS02870	COG1088	dTDP-glucose 4,6-dehydratase activity
QI37_RS02945	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
QI37_RS02950	COG0564	pseudouridine synthase activity
QI37_RS02955	COG2992	FlgJ-related protein
QI37_RS02960	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
QI37_RS02965	COG1127	ABC transporter
QI37_RS02985	COG1385	rRNA (uridine-N3-)-methyltransferase activity
QI37_RS02995	COG0318	PFAM AMP-dependent synthetase and ligase
QI37_RS03005	COG0477	Major facilitator Superfamily
QI37_RS03020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
QI37_RS03035	COG0443	Heat shock 70 kDa protein
QI37_RS03040	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
QI37_RS03045	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
QI37_RS03055	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
QI37_RS03060	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
QI37_RS03075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
QI37_RS03400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
QI37_RS03425	COG3723	Recombinational DNA repair protein, rece pathway
QI37_RS03475	COG0583	DNA-binding transcription factor activity
QI37_RS03485	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
QI37_RS03490	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
QI37_RS03495	COG1758	RNA polymerase activity
QI37_RS03510	COG0316	Belongs to the HesB IscA family
QI37_RS03520	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
QI37_RS03530	COG3116	cell division
QI37_RS03545	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
QI37_RS03560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
QI37_RS03575	COG0045	succinate-CoA ligase (ADP-forming) activity
QI37_RS03580	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
QI37_RS03600	COG0628	permease
QI37_RS03610	COG3104	oligopeptide transport
QI37_RS03615	COG1446	asparaginase
QI37_RS03640	COG0546	phosphoglycolate phosphatase activity
QI37_RS03645	COG0492	ferredoxin-NADP+ reductase activity
QI37_RS03655	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
QI37_RS03675	COG3104	oligopeptide transport
QI37_RS03690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
QI37_RS03700	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
QI37_RS03715	COG0439	Biotin carboxylase
QI37_RS03730	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
QI37_RS03740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
QI37_RS03750	COG0531	amino acid
QI37_RS03760	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
QI37_RS03765	COG0113	porphobilinogen synthase activity
QI37_RS03770	COG1534	Rna-binding protein
QI37_RS03775	COG0470	DNA polymerase III
QI37_RS03780	COG0616	signal peptide processing
QI37_RS03785	COG0625	glutathione transferase activity
QI37_RS03790	COG2920	part of a sulfur-relay system
QI37_RS03795	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
QI37_RS03800	COG0772	Belongs to the SEDS family
QI37_RS03815	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
QI37_RS03820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
QI37_RS03825	COG3104	oligopeptide transport
QI37_RS03830	COG0488	(ABC) transporter
QI37_RS03845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
QI37_RS03850	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
QI37_RS03855	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
QI37_RS03865	COG3104	oligopeptide transport
QI37_RS03875	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
QI37_RS03890	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
QI37_RS03910	COG1640	4-alpha-glucanotransferase
QI37_RS03915	COG0058	SHG alpha-glucan phosphorylase activity
QI37_RS03930	COG0033	Phosphoglucomutase
QI37_RS03935	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
QI37_RS03940	COG1523	belongs to the glycosyl hydrolase 13 family
QI37_RS03955	COG3706	GGDEF domain
QI37_RS03960	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
QI37_RS03965	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
QI37_RS03975	COG0404	The glycine cleavage system catalyzes the degradation of glycine
QI37_RS03995	COG0242	peptide deformylase activity
QI37_RS04000	COG0587	DNA-directed DNA polymerase activity
QI37_RS04010	COG0741	lytic transglycosylase activity
QI37_RS04020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
QI37_RS04035	COG0024	Methionine aminopeptidase
QI37_RS04070	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
QI37_RS04075	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
QI37_RS04080	COG1056	cytidyltransferase-related domain
QI37_RS04080	COG1051	belongs to the nudix hydrolase family
QI37_RS04100	COG1994	Peptidase M50
QI37_RS04105	COG3104	oligopeptide transport
QI37_RS04190	COG2271	Major facilitator Superfamily
QI37_RS04195	COG1739	Uncharacterized protein family UPF0029
QI37_RS04200	COG0009	L-threonylcarbamoyladenylate synthase
QI37_RS04205	COG2917	probably involved in intracellular septation
QI37_RS04215	COG0837	glucose binding
QI37_RS04220	COG2226	methyltransferase
QI37_RS04230	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
QI37_RS04235	COG0537	adenosine 5'-monophosphoramidase activity
QI37_RS04240	COG1040	competence protein
QI37_RS04275	COG2226	methyltransferase
QI37_RS04285	COG0812	UDP-N-acetylmuramate dehydrogenase activity
QI37_RS04290	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
QI37_RS04315	COG0281	malic enzyme
QI37_RS04320	COG0196	riboflavin kinase activity
QI37_RS04330	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
QI37_RS04360	COG3240	lipase activity
QI37_RS04365	COG0519	Catalyzes the synthesis of GMP from XMP
QI37_RS04370	COG1475	DNA binding
QI37_RS04375	COG1192	Involved in chromosome partitioning
QI37_RS04415	COG0339	signal peptide processing
QI37_RS04420	COG0792	nuclease activity
QI37_RS04450	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
QI37_RS04460	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
QI37_RS04465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
QI37_RS04470	COG0671	phosphoesterase, PA-phosphatase related
QI37_RS04475	COG4969	Belongs to the N-Me-Phe pilin family
QI37_RS04485	COG0497	DNA recombination
QI37_RS04490	COG0436	Aminotransferase
QI37_RS04500	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
QI37_RS04505	COG0662	Cupin 2, conserved barrel domain protein
QI37_RS04505	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
QI37_RS04510	COG0833	amino acid
QI37_RS04520	COG0753	catalase activity
QI37_RS04525	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
QI37_RS04525	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
QI37_RS04615	COG0583	DNA-binding transcription factor activity
QI37_RS04620	COG1704	LemA family
QI37_RS04675	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
QI37_RS04685	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
QI37_RS04710	COG0730	response to heat
QI37_RS04730	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
QI37_RS04760	COG0811	peptide transport
QI37_RS04770	COG1183	phosphatidylcholine synthase activity
QI37_RS04795	COG0758	DNA mediated transformation
QI37_RS04800	COG2252	PERMEase
QI37_RS04815	COG2095	MarC family integral membrane protein
QI37_RS04820	COG1051	belongs to the nudix hydrolase family
QI37_RS04825	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
QI37_RS04850	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
QI37_RS04865	COG0227	Belongs to the bacterial ribosomal protein bL28 family
QI37_RS04870	COG0267	Belongs to the bacterial ribosomal protein bL33 family
QI37_RS04875	COG0850	regulation of cytokinetic process
QI37_RS04885	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
QI37_RS04890	COG1127	ABC transporter
QI37_RS04895	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
QI37_RS04900	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
QI37_RS04935	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
QI37_RS04945	COG0531	amino acid
QI37_RS04955	COG2890	protein-(glutamine-N5) methyltransferase activity
QI37_RS04995	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
QI37_RS05000	COG2814	Major facilitator Superfamily
QI37_RS05030	COG1131	(ABC) transporter
QI37_RS05035	COG0842	Transport permease protein
QI37_RS05040	COG0494	nUDIX hydrolase
QI37_RS05070	COG4974	Belongs to the 'phage' integrase family
QI37_RS05075	COG0335	large ribosomal subunit rRNA binding
QI37_RS05080	COG0336	Belongs to the RNA methyltransferase TrmD family
QI37_RS05085	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
QI37_RS05095	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
QI37_RS05110	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
QI37_RS05120	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
QI37_RS05140	COG0081	regulation of translation
QI37_RS05145	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
QI37_RS05155	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
QI37_RS05190	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
QI37_RS05205	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
QI37_RS05215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
QI37_RS05240	COG0210	DNA helicase
QI37_RS05250	COG0668	transmembrane transport
QI37_RS05255	COG0552	protein localization to endoplasmic reticulum
QI37_RS05265	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
QI37_RS05275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
QI37_RS05280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
QI37_RS05285	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
QI37_RS05300	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
QI37_RS05300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
QI37_RS05305	COG1663	tetraacyldisaccharide 4'-kinase activity
QI37_RS05325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
QI37_RS05330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
QI37_RS05370	COG1271	oxidase subunit
QI37_RS05375	COG1294	oxidase, subunit
QI37_RS05410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
QI37_RS05430	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
QI37_RS05435	COG0149	triose-phosphate isomerase activity
QI37_RS05460	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
QI37_RS05465	COG1053	succinate dehydrogenase
QI37_RS05470	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
QI37_RS05475	COG2009	succinate dehydrogenase
QI37_RS05485	COG2223	nitrite transmembrane transporter activity
QI37_RS05495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
QI37_RS05500	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
QI37_RS05510	COG0355	proton-transporting ATP synthase activity, rotational mechanism
QI37_RS05520	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
QI37_RS05560	COG0564	pseudouridine synthase activity
QI37_RS05565	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
QI37_RS05590	COG0195	Participates in both transcription termination and antitermination
QI37_RS05590	COG2251	uridine kinase activity
QI37_RS05595	COG0779	Required for maturation of 30S ribosomal subunits
QI37_RS05605	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
QI37_RS05610	COG0606	chelatase, subunit chli
QI37_RS05625	COG2610	gluconate transmembrane transporter activity
QI37_RS05630	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
QI37_RS05650	COG0713	ATP synthesis coupled electron transport
QI37_RS05655	COG0839	Belongs to the complex I subunit 6 family
QI37_RS05665	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
QI37_RS05670	COG1034	ATP synthesis coupled electron transport
QI37_RS05680	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
QI37_RS05685	COG0649	NAD binding
QI37_RS05700	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
QI37_RS05710	COG4264	IucA IucC family
QI37_RS05720	COG0019	diaminopimelate decarboxylase activity
QI37_RS05725	COG2814	Major facilitator Superfamily
QI37_RS05745	COG0154	amidase activity
QI37_RS05750	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
QI37_RS05765	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
QI37_RS05790	COG0047	phosphoribosylformylglycinamidine synthase activity
QI37_RS05790	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
QI37_RS05795	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
QI37_RS05800	COG0076	glutamate decarboxylase activity
QI37_RS05820	COG0826	peptidase U32
QI37_RS05825	COG2814	Major facilitator Superfamily
QI37_RS05835	COG4178	(ABC) transporter
QI37_RS05840	COG0531	amino acid
QI37_RS05845	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
QI37_RS05850	COG0814	amino acid
QI37_RS05925	COG0505	Belongs to the CarA family
QI37_RS05930	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
QI37_RS05945	COG0814	amino acid
QI37_RS05950	COG0531	amino acid
QI37_RS05965	COG0592	DNA-directed DNA polymerase activity
QI37_RS05975	COG1530	ribonuclease E activity
QI37_RS05995	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
QI37_RS06000	COG0512	Glutamine amidotransferase of anthranilate synthase
QI37_RS06005	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
QI37_RS06015	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
QI37_RS06015	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
QI37_RS06030	COG0134	indole-3-glycerol-phosphate synthase activity
QI37_RS06030	COG0135	phosphoribosylanthranilate isomerase activity
QI37_RS06035	COG0308	aminopeptidase N
QI37_RS06045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
QI37_RS06070	COG0488	(ABC) transporter
QI37_RS06085	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
QI37_RS06095	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
QI37_RS06120	COG0298	carbon dioxide binding
QI37_RS06125	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
QI37_RS06135	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
QI37_RS06150	COG0375	protein maturation
QI37_RS06155	COG0477	Major facilitator Superfamily
QI37_RS06185	COG1012	belongs to the aldehyde dehydrogenase family
QI37_RS06195	COG0204	Acyl-transferase
QI37_RS06205	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
QI37_RS06240	COG0542	response to heat
QI37_RS06350	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
QI37_RS06370	COG2988	succinylglutamate desuccinylase activity
QI37_RS06375	COG2095	MarC family integral membrane protein
QI37_RS06380	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
QI37_RS06405	COG3201	nicotinamide mononucleotide transporter
QI37_RS06415	COG0284	orotidine-5'-phosphate decarboxylase activity
QI37_RS06435	COG0287	Prephenate dehydrogenase
QI37_RS06435	COG1605	Chorismate mutase
QI37_RS06445	COG3104	oligopeptide transport
QI37_RS06450	COG0473	3-isopropylmalate dehydrogenase activity
QI37_RS06460	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
QI37_RS06465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
QI37_RS06470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
QI37_RS06475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
QI37_RS06475	COG0574	Belongs to the PEP-utilizing enzyme family
QI37_RS06480	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
QI37_RS06505	COG1560	Kdo2-lipid A biosynthetic process
QI37_RS06510	COG1560	Kdo2-lipid A biosynthetic process
QI37_RS06515	COG0706	membrane insertase activity
QI37_RS06520	COG0594	ribonuclease P activity
QI37_RS06530	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
QI37_RS06580	COG0589	response to stress
QI37_RS06590	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
QI37_RS06600	COG1984	allophanate hydrolase subunit 2
QI37_RS06605	COG2194	sulfuric ester hydrolase activity
QI37_RS06610	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
QI37_RS06640	COG0114	fumarate hydratase activity
QI37_RS06650	COG0814	amino acid
QI37_RS06660	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
QI37_RS06665	COG0583	DNA-binding transcription factor activity
QI37_RS06680	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
QI37_RS06700	COG0482	sulfurtransferase activity
QI37_RS06710	COG0242	peptide deformylase activity
QI37_RS06720	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
QI37_RS06720	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
QI37_RS06725	COG0307	riboflavin synthase, alpha
QI37_RS06730	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
QI37_RS06730	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
QI37_RS06740	COG3104	oligopeptide transport
QI37_RS06750	COG0616	signal peptide processing
QI37_RS06760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
QI37_RS06770	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
QI37_RS06780	COG0629	single-stranded DNA binding
QI37_RS06815	COG0280	phosphate acetyltransferase
QI37_RS06815	COG0857	belongs to the CobB CobQ family
QI37_RS06835	COG1597	lipid kinase activity
QI37_RS06840	COG1012	belongs to the aldehyde dehydrogenase family
QI37_RS06850	COG3153	acetyltransferase
QI37_RS06850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
QI37_RS06860	COG0557	exoribonuclease II activity
QI37_RS06900	COG1116	anion transmembrane transporter activity
QI37_RS06915	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
QI37_RS06925	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
QI37_RS06945	COG0762	integral membrane protein
QI37_RS06955	COG4067	protein conserved in archaea
QI37_RS06955	COG0189	ligase activity
QI37_RS06980	COG0204	Acyl-transferase
QI37_RS06990	COG0009	L-threonylcarbamoyladenylate synthase
QI37_RS07005	COG1181	Belongs to the D-alanine--D-alanine ligase family
QI37_RS07010	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
QI37_RS07035	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
QI37_RS07050	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
QI37_RS07060	COG2862	Uncharacterized protein family, UPF0114
QI37_RS07080	COG2066	Belongs to the glutaminase family
QI37_RS07095	COG3040	lipid binding
QI37_RS07100	COG0814	amino acid
QI37_RS07105	COG0138	bifunctional purine biosynthesis protein purh
QI37_RS07130	COG1121	(ABC) transporter
QI37_RS07155	COG1295	ribonuclease BN
QI37_RS07165	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
QI37_RS07175	COG2814	Major facilitator Superfamily
QI37_RS07180	COG1294	oxidase, subunit
QI37_RS07190	COG2814	Major facilitator Superfamily
QI37_RS07195	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
QI37_RS07200	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
QI37_RS07210	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
QI37_RS07230	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
QI37_RS07240	COG0714	Associated with various cellular activities
QI37_RS07295	COG0525	valine-tRNA ligase activity
QI37_RS07305	COG2184	nucleotidyltransferase activity
QI37_RS07315	COG1304	FMN binding
QI37_RS07360	COG1288	antiporter activity
QI37_RS07375	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
QI37_RS07400	COG0233	cytoplasmic translational termination
QI37_RS07405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
QI37_RS07410	COG0575	Belongs to the CDS family
QI37_RS07415	COG0756	dUTP diphosphatase activity
QI37_RS07420	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
QI37_RS07435	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
QI37_RS07445	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
QI37_RS07450	COG0088	Forms part of the polypeptide exit tunnel
QI37_RS07465	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
QI37_RS07470	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
QI37_RS07480	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
QI37_RS07500	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
QI37_RS07510	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
QI37_RS07515	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
QI37_RS07545	COG0201	protein transport
QI37_RS07555	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
QI37_RS07565	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
QI37_RS07580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
QI37_RS07610	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
QI37_RS07615	COG0285	dihydrofolate synthase activity
QI37_RS07620	COG0802	atpase or kinase
QI37_RS07635	COG2918	glutathione biosynthetic process
QI37_RS07665	COG2814	Major facilitator Superfamily
QI37_RS07670	COG1621	beta-fructofuranosidase activity
QI37_RS07705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
QI37_RS07720	COG1674	ftsk spoiiie
QI37_RS07760	COG0833	amino acid
QI37_RS07765	COG2945	thiolester hydrolase activity
QI37_RS07770	COG1494	fructose-1,6-bisphosphatase
QI37_RS07785	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
QI37_RS07795	COG1253	flavin adenine dinucleotide binding
QI37_RS07860	COG0215	cysteine-tRNA ligase activity
QI37_RS07865	COG2890	protein-(glutamine-N5) methyltransferase activity
QI37_RS07880	COG3328	transposase activity
QI37_RS07895	COG3022	response to hydroperoxide
QI37_RS07900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
QI37_RS07905	COG2814	Major facilitator Superfamily
QI37_RS07910	COG2814	Major facilitator Superfamily
QI37_RS07925	COG0596	Alpha beta hydrolase
QI37_RS07930	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
QI37_RS07950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
QI37_RS07955	COG1028	Short-chain dehydrogenase reductase Sdr
QI37_RS07970	COG2081	HI0933 family
QI37_RS07975	COG1741	Belongs to the pirin family
QI37_RS07985	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
QI37_RS08000	COG0531	amino acid
QI37_RS08015	COG0398	Pfam SNARE associated Golgi protein
QI37_RS08020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
QI37_RS08045	COG0814	amino acid
QI37_RS08055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
QI37_RS08080	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
QI37_RS08085	COG0814	amino acid
QI37_RS08135	COG0531	amino acid
QI37_RS08175	COG0237	dephospho-CoA kinase activity
QI37_RS08195	COG0508	dehydrogenase complex catalyzes the overall conversion of
QI37_RS08200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
QI37_RS08225	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
QI37_RS08240	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
QI37_RS08250	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
QI37_RS08275	COG1183	phosphatidylcholine synthase activity
QI37_RS08280	COG0142	geranyltranstransferase activity
QI37_RS08285	COG1519	Transferase
QI37_RS08290	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
QI37_RS08295	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
QI37_RS08305	COG0681	Belongs to the peptidase S26 family
QI37_RS08310	COG0571	ribonuclease III activity
QI37_RS08320	COG0557	exoribonuclease II activity
QI37_RS08350	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
QI37_RS08365	COG5002	protein histidine kinase activity
QI37_RS08385	COG0500	methyltransferase
QI37_RS08425	COG1834	amidinotransferase
QI37_RS08430	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
QI37_RS08440	COG2814	Major facilitator Superfamily
QI37_RS08450	COG0183	Belongs to the thiolase family
QI37_RS08455	COG1250	3-hydroxyacyl-CoA dehydrogenase
QI37_RS08455	COG1024	Enoyl-CoA hydratase
QI37_RS08460	COG1960	acyl-CoA dehydrogenase activity
QI37_RS08465	COG0318	PFAM AMP-dependent synthetase and ligase
QI37_RS08470	COG1393	Belongs to the ArsC family
QI37_RS08490	COG1643	Atp-dependent helicase
QI37_RS08495	COG1086	Polysaccharide biosynthesis protein
QI37_RS08500	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
QI37_RS08505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
QI37_RS08530	COG1215	transferase activity, transferring glycosyl groups
QI37_RS08545	COG3475	LICD family
QI37_RS08550	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
QI37_RS08575	COG3118	belongs to the thioredoxin family
QI37_RS08580	COG0248	Ppx GppA phosphatase
QI37_RS08585	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
QI37_RS08605	COG0084	hydrolase, TatD family'
QI37_RS08615	COG0730	response to heat
QI37_RS08620	COG1131	(ABC) transporter
QI37_RS08625	COG0842	Transport permease protein
QI37_RS08630	COG0463	Glycosyl transferase, family 2
QI37_RS08645	COG1280	lysine exporter protein (LysE YggA)
QI37_RS08665	COG0640	Transcriptional regulator
QI37_RS08670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
QI37_RS08675	COG0446	pyridine nucleotide-disulphide oxidoreductase
QI37_RS08680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
QI37_RS08695	COG2983	Belongs to the UPF0260 family
QI37_RS08705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
QI37_RS08715	COG0436	Aminotransferase
QI37_RS08745	COG2166	iron-sulfur cluster assembly
QI37_RS08765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
QI37_RS08805	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
QI37_RS08825	COG1074	ATP-dependent DNA helicase activity
QI37_RS08830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
QI37_RS08840	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
QI37_RS08860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
QI37_RS08860	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
QI37_RS08865	COG0483	inositol monophosphate 1-phosphatase activity
QI37_RS08870	COG2855	membrane
QI37_RS08880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
QI37_RS08880	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
QI37_RS08890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
QI37_RS08895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
QI37_RS08900	COG1028	Short-chain dehydrogenase reductase Sdr
QI37_RS08905	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
QI37_RS08915	COG0416	fatty acid biosynthetic process
QI37_RS08920	COG0333	Belongs to the bacterial ribosomal protein bL32 family
QI37_RS08925	COG1399	metal-binding, possibly nucleic acid-binding protein
QI37_RS08940	COG0126	phosphoglycerate kinase activity
QI37_RS08950	COG0191	fructose-bisphosphate aldolase activity
QI37_RS08970	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
QI37_RS08990	COG0477	Major facilitator Superfamily
QI37_RS08995	COG0232	Belongs to the dGTPase family. Type 2 subfamily
QI37_RS09000	COG0137	argininosuccinate synthase activity
QI37_RS09005	COG0165	Argininosuccinate lyase
QI37_RS09010	COG1438	arginine binding
QI37_RS09020	COG1028	Short-chain dehydrogenase reductase Sdr
QI37_RS09025	COG2271	Major facilitator Superfamily
QI37_RS09030	COG0659	secondary active sulfate transmembrane transporter activity
QI37_RS09035	COG0251	oxidation-reduction process
QI37_RS09050	COG3240	lipase activity
QI37_RS09055	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
QI37_RS09060	COG4988	ABC transporter
QI37_RS09090	COG1940	carbohydrate kinase activity
QI37_RS09105	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
QI37_RS09115	COG0277	FAD linked oxidase domain protein
QI37_RS09115	COG0247	lactate metabolic process
QI37_RS09125	COG3104	oligopeptide transport
QI37_RS09135	COG0295	cytidine deaminase activity
QI37_RS09145	COG1472	Belongs to the glycosyl hydrolase 3 family
QI37_RS09155	COG0517	IMP dehydrogenase activity
QI37_RS09155	COG0516	GMP reductase activity
QI37_RS09215	COG0813	purine-nucleoside phosphorylase activity
QI37_RS09220	COG3104	oligopeptide transport
QI37_RS09240	COG0519	Catalyzes the synthesis of GMP from XMP
QI37_RS09245	COG2271	Major facilitator Superfamily
QI37_RS09250	COG0261	This protein binds to 23S rRNA in the presence of protein L20
QI37_RS09255	COG0211	Belongs to the bacterial ribosomal protein bL27 family
QI37_RS09265	COG0477	Major facilitator Superfamily
QI37_RS09270	COG1177	transmembrane transport
QI37_RS09275	COG1176	ABC-type spermidine putrescine transport system, permease component I
QI37_RS09280	COG3842	ATPase activity
QI37_RS09315	COG0531	amino acid
QI37_RS09320	COG0077	Prephenate dehydratase
QI37_RS09320	COG1605	Chorismate mutase
QI37_RS09335	COG1760	l-serine dehydratase
QI37_RS09340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
QI37_RS09345	COG0316	Belongs to the HesB IscA family
QI37_RS09350	COG2151	metal-sulfur cluster biosynthetic enzyme
QI37_RS09365	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
QI37_RS09380	COG0017	Asparaginyl-tRNA synthetase
QI37_RS09390	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
QI37_RS09400	COG1546	Belongs to the CinA family
QI37_RS09400	COG1058	Belongs to the CinA family
QI37_RS09405	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
QI37_RS09405	COG0189	ligase activity
QI37_RS09410	COG1181	Belongs to the D-alanine--D-alanine ligase family
QI37_RS09410	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
QI37_RS09425	COG1464	Belongs to the NlpA lipoprotein family
QI37_RS09435	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
QI37_RS09440	COG0343	queuine tRNA-ribosyltransferase activity
QI37_RS09465	COG1940	carbohydrate kinase activity
QI37_RS09490	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
QI37_RS09495	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
QI37_RS09500	COG0814	amino acid
QI37_RS09510	COG0156	8-amino-7-oxononanoate synthase activity
QI37_RS09555	COG1862	Preprotein translocase
QI37_RS09560	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
QI37_RS09565	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
QI37_RS09575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
QI37_RS09585	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
QI37_RS09600	COG0252	asparaginase activity
QI37_RS09605	COG0288	reversible hydration of carbon dioxide
QI37_RS09635	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
QI37_RS09645	COG0544	peptidyl-prolyl cis-trans isomerase activity
QI37_RS09650	COG0740	serine-type endopeptidase activity
QI37_RS09655	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
QI37_RS09660	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
QI37_RS09675	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
QI37_RS09690	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
QI37_RS09705	COG0330	HflC and HflK could
QI37_RS09710	COG0330	HflC and HflK could
QI37_RS09715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
QI37_RS09725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
QI37_RS09730	COG0670	Belongs to the BI1 family
QI37_RS09745	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
QI37_RS09750	COG2878	Part of a membrane complex involved in electron transport
QI37_RS09755	COG2999	glutathione oxidoreductase activity
QI37_RS09770	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
QI37_RS09775	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
QI37_RS09785	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
QI37_RS09800	COG1322	Protein conserved in bacteria
QI37_RS09840	COG0477	Major facilitator Superfamily
QI37_RS09845	COG0515	serine threonine protein kinase
QI37_RS09860	COG3397	chitin binding
QI37_RS09870	COG3646	Phage regulatory protein
QI37_RS09870	COG3645	SOS response
QI37_RS09875	COG1215	transferase activity, transferring glycosyl groups
QI37_RS09890	COG1215	transferase activity, transferring glycosyl groups
QI37_RS09890	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
QI37_RS09940	COG0582	viral genome integration into host DNA
QI37_RS10015	COG0789	Transcriptional regulator
QI37_RS10025	COG2865	translation initiation factor activity