locus-tag	class	description
FIP56_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FIP56_RS00015	COG0477	Major facilitator Superfamily
FIP56_RS00020	COG0531	amino acid
FIP56_RS00035	COG3676	manually curated
FIP56_RS00050	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FIP56_RS00070	COG0814	amino acid
FIP56_RS00080	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FIP56_RS00085	COG0505	Belongs to the CarA family
FIP56_RS00130	COG1396	sequence-specific DNA binding
FIP56_RS00175	COG1605	Chorismate mutase
FIP56_RS00175	COG0287	Prephenate dehydrogenase
FIP56_RS00180	COG1490	D-aminoacyl-tRNA deacylase activity
FIP56_RS00190	COG1621	beta-fructofuranosidase activity
FIP56_RS00195	COG3104	oligopeptide transport
FIP56_RS00200	COG0473	3-isopropylmalate dehydrogenase activity
FIP56_RS00210	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FIP56_RS00215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FIP56_RS00225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FIP56_RS00225	COG0574	Belongs to the PEP-utilizing enzyme family
FIP56_RS00235	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FIP56_RS00260	COG1560	Kdo2-lipid A biosynthetic process
FIP56_RS00265	COG1560	Kdo2-lipid A biosynthetic process
FIP56_RS00270	COG1560	Kdo2-lipid A biosynthetic process
FIP56_RS00275	COG0706	membrane insertase activity
FIP56_RS00285	COG0594	ribonuclease P activity
FIP56_RS00300	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FIP56_RS00310	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FIP56_RS00335	COG0589	response to stress
FIP56_RS00345	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FIP56_RS00355	COG1984	allophanate hydrolase subunit 2
FIP56_RS00370	COG3038	cytochrome b561
FIP56_RS00380	COG0778	Nitroreductase
FIP56_RS00385	COG0114	fumarate hydratase activity
FIP56_RS00395	COG0814	amino acid
FIP56_RS00400	COG0357	Ribosomal RNA small subunit methyltransferase G
FIP56_RS00405	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FIP56_RS00415	COG2814	Major facilitator Superfamily
FIP56_RS00420	COG2814	Major facilitator Superfamily
FIP56_RS00425	COG2814	Major facilitator Superfamily
FIP56_RS00440	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FIP56_RS00445	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIP56_RS00455	COG0481	GTPase activity
FIP56_RS00470	COG0242	peptide deformylase activity
FIP56_RS00480	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIP56_RS00480	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FIP56_RS00490	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIP56_RS00490	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FIP56_RS00525	COG3961	Belongs to the TPP enzyme family
FIP56_RS00535	COG0616	signal peptide processing
FIP56_RS00565	COG0629	single-stranded DNA binding
FIP56_RS00575	COG0857	belongs to the CobB CobQ family
FIP56_RS00575	COG0280	phosphate acetyltransferase
FIP56_RS00580	COG1012	belongs to the aldehyde dehydrogenase family
FIP56_RS00595	COG0626	cystathionine gamma-synthase activity
FIP56_RS00605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIP56_RS00605	COG3153	acetyltransferase
FIP56_RS00615	COG0557	exoribonuclease II activity
FIP56_RS00625	COG0181	hydroxymethylbilane synthase activity
FIP56_RS00630	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FIP56_RS00655	COG1116	anion transmembrane transporter activity
FIP56_RS00675	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FIP56_RS00685	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FIP56_RS00700	COG0762	integral membrane protein
FIP56_RS00705	COG0456	acetyltransferase
FIP56_RS00710	COG0189	ligase activity
FIP56_RS00710	COG4067	protein conserved in archaea
FIP56_RS00715	COG0658	competence protein
FIP56_RS00715	COG2333	competence protein COMEC
FIP56_RS00720	COG0204	Acyl-transferase
FIP56_RS00735	COG0009	L-threonylcarbamoyladenylate synthase
FIP56_RS00755	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FIP56_RS00775	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FIP56_RS00785	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FIP56_RS00795	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FIP56_RS00805	COG2862	Uncharacterized protein family, UPF0114
FIP56_RS00815	COG2066	Belongs to the glutaminase family
FIP56_RS00830	COG3040	lipid binding
FIP56_RS00835	COG0814	amino acid
FIP56_RS00840	COG0138	bifunctional purine biosynthesis protein purh
FIP56_RS00845	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FIP56_RS00870	COG0803	Belongs to the bacterial solute-binding protein 9 family
FIP56_RS00890	COG1295	ribonuclease BN
FIP56_RS00900	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FIP56_RS00920	COG1294	oxidase, subunit
FIP56_RS00930	COG2814	Major facilitator Superfamily
FIP56_RS00935	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FIP56_RS00940	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FIP56_RS00945	COG1845	cytochrome c oxidase, subunit III
FIP56_RS00950	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FIP56_RS00970	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FIP56_RS00980	COG0714	Associated with various cellular activities
FIP56_RS01035	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FIP56_RS01035	COG2755	lipolytic protein G-D-S-L family
FIP56_RS01040	COG0525	valine-tRNA ligase activity
FIP56_RS01050	COG1304	FMN binding
FIP56_RS01080	COG0735	belongs to the Fur family
FIP56_RS01090	COG0531	amino acid
FIP56_RS01115	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FIP56_RS01130	COG0052	Belongs to the universal ribosomal protein uS2 family
FIP56_RS01145	COG0233	cytoplasmic translational termination
FIP56_RS01150	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FIP56_RS01155	COG4589	Belongs to the CDS family
FIP56_RS01160	COG0756	dUTP diphosphatase activity
FIP56_RS01165	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FIP56_RS01180	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FIP56_RS01190	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FIP56_RS01195	COG0088	Forms part of the polypeptide exit tunnel
FIP56_RS01205	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FIP56_RS01210	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FIP56_RS01215	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FIP56_RS01225	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FIP56_RS01245	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FIP56_RS01255	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FIP56_RS01260	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FIP56_RS01290	COG0201	protein transport
FIP56_RS01300	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FIP56_RS01310	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FIP56_RS01325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FIP56_RS01330	COG0326	Molecular chaperone. Has ATPase activity
FIP56_RS01340	COG2988	succinylglutamate desuccinylase activity
FIP56_RS01350	COG3387	PFAM Glycoside hydrolase 15-related
FIP56_RS01355	COG1438	arginine binding
FIP56_RS01360	COG0165	Argininosuccinate lyase
FIP56_RS01365	COG0137	argininosuccinate synthase activity
FIP56_RS01370	COG1288	antiporter activity
FIP56_RS01375	COG3397	chitin binding
FIP56_RS01390	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FIP56_RS01405	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FIP56_RS01410	COG0285	dihydrofolate synthase activity
FIP56_RS01415	COG0802	atpase or kinase
FIP56_RS01425	COG0728	peptidoglycan biosynthetic process
FIP56_RS01430	COG2918	glutathione biosynthetic process
FIP56_RS01445	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FIP56_RS01460	COG0330	HflC and HflK could
FIP56_RS01470	COG2217	Heavy metal translocating P-type atpase
FIP56_RS01480	COG0583	DNA-binding transcription factor activity
FIP56_RS01490	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FIP56_RS01500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIP56_RS01505	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FIP56_RS01535	COG1674	ftsk spoiiie
FIP56_RS01545	COG0436	Aminotransferase
FIP56_RS01550	COG0527	aspartate kinase activity
FIP56_RS01555	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FIP56_RS01560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIP56_RS01570	COG0019	diaminopimelate decarboxylase activity
FIP56_RS01575	COG0833	amino acid
FIP56_RS01585	COG1494	fructose-1,6-bisphosphatase
FIP56_RS01595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIP56_RS01605	COG1253	flavin adenine dinucleotide binding
FIP56_RS01670	COG0531	amino acid
FIP56_RS01680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FIP56_RS01685	COG2853	Lipoprotein
FIP56_RS01710	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIP56_RS01715	COG1127	ABC transporter
FIP56_RS01730	COG0850	regulation of cytokinetic process
FIP56_RS01735	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FIP56_RS01740	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FIP56_RS01765	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FIP56_RS01785	COG1051	belongs to the nudix hydrolase family
FIP56_RS01790	COG2095	MarC family integral membrane protein
FIP56_RS01810	COG0758	DNA mediated transformation
FIP56_RS01825	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FIP56_RS01845	COG0811	peptide transport
FIP56_RS01870	COG2885	chlorophyll binding
FIP56_RS01875	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FIP56_RS01890	COG0415	Belongs to the DNA photolyase family
FIP56_RS01895	COG3046	protein related to deoxyribodipyrimidine photolyase
FIP56_RS01910	COG0385	Bile acid
FIP56_RS01920	COG0730	response to heat
FIP56_RS01945	COG0246	Mannitol dehydrogenase
FIP56_RS01955	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FIP56_RS01965	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FIP56_RS01975	COG0501	Belongs to the peptidase M48B family
FIP56_RS01980	COG1704	LemA family
FIP56_RS01985	COG0583	DNA-binding transcription factor activity
FIP56_RS02040	COG1268	BioY protein
FIP56_RS02050	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIP56_RS02050	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIP56_RS02065	COG0833	amino acid
FIP56_RS02075	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FIP56_RS02085	COG0436	Aminotransferase
FIP56_RS02090	COG0497	DNA recombination
FIP56_RS02105	COG0671	phosphoesterase, PA-phosphatase related
FIP56_RS02115	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FIP56_RS02125	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FIP56_RS02140	COG1028	Short-chain dehydrogenase reductase Sdr
FIP56_RS02150	COG0339	signal peptide processing
FIP56_RS02185	COG3676	manually curated
FIP56_RS02200	COG1192	Involved in chromosome partitioning
FIP56_RS02205	COG1475	DNA binding
FIP56_RS02210	COG0519	Catalyzes the synthesis of GMP from XMP
FIP56_RS02220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FIP56_RS02230	COG2207	Transcriptional regulator
FIP56_RS02235	COG2807	transmembrane transport
FIP56_RS02255	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FIP56_RS02260	COG0196	riboflavin kinase activity
FIP56_RS02265	COG0281	malic enzyme
FIP56_RS02285	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FIP56_RS02290	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FIP56_RS02300	COG4106	trans-aconitate 2-methyltransferase activity
FIP56_RS02305	COG3300	MHYT domain
FIP56_RS02305	COG5001	Diguanylate cyclase
FIP56_RS02310	COG2203	Gaf domain
FIP56_RS02310	COG2199	diguanylate cyclase activity
FIP56_RS02320	COG0463	Glycosyl transferase, family 2
FIP56_RS02330	COG2200	EAL domain
FIP56_RS02330	COG2202	Pas domain
FIP56_RS02330	COG2199	diguanylate cyclase activity
FIP56_RS02335	COG1040	competence protein
FIP56_RS02340	COG0537	adenosine 5'-monophosphoramidase activity
FIP56_RS02345	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FIP56_RS02355	COG2226	methyltransferase
FIP56_RS02360	COG0837	glucose binding
FIP56_RS02380	COG0009	L-threonylcarbamoyladenylate synthase
FIP56_RS02385	COG1739	Uncharacterized protein family UPF0029
FIP56_RS02390	COG2271	Major facilitator Superfamily
FIP56_RS02430	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIP56_RS02450	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIP56_RS02465	COG0583	DNA-binding transcription factor activity
FIP56_RS02485	COG1183	phosphatidylcholine synthase activity
FIP56_RS02490	COG0142	geranyltranstransferase activity
FIP56_RS02495	COG1519	Transferase
FIP56_RS02500	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FIP56_RS02505	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FIP56_RS02515	COG0681	Belongs to the peptidase S26 family
FIP56_RS02520	COG0571	ribonuclease III activity
FIP56_RS02530	COG0557	exoribonuclease II activity
FIP56_RS02535	COG4989	oxidoreductase activity
FIP56_RS02545	COG2211	Major facilitator Superfamily
FIP56_RS02570	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FIP56_RS02590	COG0745	RESPONSE REGULATOR receiver
FIP56_RS02605	COG0500	methyltransferase
FIP56_RS02615	COG3676	manually curated
FIP56_RS02650	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FIP56_RS02660	COG2814	Major facilitator Superfamily
FIP56_RS02670	COG0183	Belongs to the thiolase family
FIP56_RS02675	COG1250	3-hydroxyacyl-CoA dehydrogenase
FIP56_RS02675	COG1024	Enoyl-CoA hydratase
FIP56_RS02680	COG1960	acyl-CoA dehydrogenase activity
FIP56_RS02685	COG0318	PFAM AMP-dependent synthetase and ligase
FIP56_RS02690	COG1393	Belongs to the ArsC family
FIP56_RS02700	COG1643	Atp-dependent helicase
FIP56_RS02705	COG1086	Polysaccharide biosynthesis protein
FIP56_RS02710	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FIP56_RS02715	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FIP56_RS02725	COG1063	alcohol dehydrogenase
FIP56_RS02740	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FIP56_RS02755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FIP56_RS02775	COG0579	oxidoreductase
FIP56_RS02780	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FIP56_RS02785	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FIP56_RS02790	COG0367	asparagine synthase
FIP56_RS02795	COG0110	maltose O-acetyltransferase activity
FIP56_RS02805	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FIP56_RS02820	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FIP56_RS02825	COG2030	dehydratase
FIP56_RS02835	COG2244	polysaccharide biosynthetic process
FIP56_RS02840	COG0367	asparagine synthase
FIP56_RS02850	COG0438	transferase activity, transferring glycosyl groups
FIP56_RS02855	COG0367	asparagine synthase
FIP56_RS02860	COG0297	glycogen (starch) synthase activity
FIP56_RS02860	COG0438	transferase activity, transferring glycosyl groups
FIP56_RS02875	COG0662	Cupin 2, conserved barrel domain protein
FIP56_RS02875	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FIP56_RS02900	COG0248	Ppx GppA phosphatase
FIP56_RS02905	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FIP56_RS02975	COG3676	manually curated
FIP56_RS03050	COG0745	RESPONSE REGULATOR receiver
FIP56_RS03055	COG0642	Histidine kinase
FIP56_RS03130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FIP56_RS03170	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FIP56_RS03175	COG0531	amino acid
FIP56_RS03185	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FIP56_RS03210	COG0439	Biotin carboxylase
FIP56_RS03215	COG0511	ligase activity, forming carbon-carbon bonds
FIP56_RS03225	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FIP56_RS03255	COG3104	oligopeptide transport
FIP56_RS03265	COG1940	carbohydrate kinase activity
FIP56_RS03270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIP56_RS03295	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FIP56_RS03310	COG0492	ferredoxin-NADP+ reductase activity
FIP56_RS03330	COG0583	DNA-binding transcription factor activity
FIP56_RS03335	COG2814	Major facilitator Superfamily
FIP56_RS03340	COG2249	NAD(P)H dehydrogenase (quinone) activity
FIP56_RS03365	COG1446	asparaginase
FIP56_RS03370	COG3104	oligopeptide transport
FIP56_RS03380	COG0628	permease
FIP56_RS03400	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FIP56_RS03455	COG1619	proteins homologs of microcin C7 resistance protein MccF
FIP56_RS03470	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FIP56_RS03475	COG0204	Acyl-transferase
FIP56_RS03475	COG0318	PFAM AMP-dependent synthetase and ligase
FIP56_RS03485	COG3116	cell division
FIP56_RS03495	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FIP56_RS03510	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FIP56_RS03515	COG0572	uridine kinase
FIP56_RS03520	COG1758	RNA polymerase activity
FIP56_RS03540	COG1940	carbohydrate kinase activity
FIP56_RS03545	COG1940	carbohydrate kinase activity
FIP56_RS03565	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FIP56_RS03570	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FIP56_RS03575	COG0814	amino acid
FIP56_RS03585	COG0156	8-amino-7-oxononanoate synthase activity
FIP56_RS03625	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FIP56_RS03700	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FIP56_RS03705	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FIP56_RS03720	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FIP56_RS03725	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FIP56_RS03730	COG0443	Heat shock 70 kDa protein
FIP56_RS03745	COG2814	Major facilitator Superfamily
FIP56_RS03750	COG2814	Major facilitator Superfamily
FIP56_RS03760	COG0673	inositol 2-dehydrogenase activity
FIP56_RS03775	COG2252	PERMEase
FIP56_RS03780	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FIP56_RS03800	COG0477	Major facilitator Superfamily
FIP56_RS03815	COG3104	oligopeptide transport
FIP56_RS03820	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FIP56_RS03840	COG1127	ABC transporter
FIP56_RS03845	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FIP56_RS03850	COG1388	LysM domain
FIP56_RS03850	COG1705	Flagellar rod assembly protein muramidase FlgJ
FIP56_RS03855	COG0564	pseudouridine synthase activity
FIP56_RS03880	COG3028	Belongs to the UPF0307 family
FIP56_RS03885	COG3676	manually curated
FIP56_RS03895	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FIP56_RS03935	COG3104	oligopeptide transport
FIP56_RS03940	COG0697	spore germination
FIP56_RS03950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FIP56_RS03955	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FIP56_RS03965	COG1530	ribonuclease E activity
FIP56_RS03970	COG1104	cysteine desulfurase activity
FIP56_RS03985	COG0586	Pfam SNARE associated Golgi protein
FIP56_RS03990	COG0586	Pfam SNARE associated Golgi protein
FIP56_RS04010	COG0519	Catalyzes the synthesis of GMP from XMP
FIP56_RS04025	COG1929	Belongs to the glycerate kinase type-1 family
FIP56_RS04030	COG2271	Major facilitator Superfamily
FIP56_RS04035	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FIP56_RS04040	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FIP56_RS04045	COG0477	Major facilitator Superfamily
FIP56_RS04055	COG1177	transmembrane transport
FIP56_RS04060	COG1176	ABC-type spermidine putrescine transport system, permease component I
FIP56_RS04065	COG3842	ATPase activity
FIP56_RS04100	COG0531	amino acid
FIP56_RS04105	COG1605	Chorismate mutase
FIP56_RS04105	COG0077	Prephenate dehydratase
FIP56_RS04115	COG1760	l-serine dehydratase
FIP56_RS04125	COG0316	Belongs to the HesB IscA family
FIP56_RS04130	COG2151	metal-sulfur cluster biosynthetic enzyme
FIP56_RS04140	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FIP56_RS04150	COG0017	Asparaginyl-tRNA synthetase
FIP56_RS04160	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FIP56_RS04175	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FIP56_RS04175	COG0189	ligase activity
FIP56_RS04180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FIP56_RS04180	COG1181	Belongs to the D-alanine--D-alanine ligase family
FIP56_RS04195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIP56_RS04200	COG0814	amino acid
FIP56_RS04205	COG1464	Belongs to the NlpA lipoprotein family
FIP56_RS04225	COG0583	DNA-binding transcription factor activity
FIP56_RS04245	COG1501	Belongs to the glycosyl hydrolase 31 family
FIP56_RS04255	COG1862	Preprotein translocase
FIP56_RS04260	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIP56_RS04265	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FIP56_RS04275	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FIP56_RS04285	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FIP56_RS04295	COG0328	RNA-DNA hybrid ribonuclease activity
FIP56_RS04300	COG0252	asparaginase activity
FIP56_RS04305	COG0288	reversible hydration of carbon dioxide
FIP56_RS04320	COG0544	peptidyl-prolyl cis-trans isomerase activity
FIP56_RS04325	COG0740	serine-type endopeptidase activity
FIP56_RS04330	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FIP56_RS04335	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FIP56_RS04350	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FIP56_RS04365	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FIP56_RS04375	COG0330	HflC and HflK could
FIP56_RS04380	COG0330	HflC and HflK could
FIP56_RS04385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FIP56_RS04390	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FIP56_RS04400	COG0129	dihydroxy-acid dehydratase activity
FIP56_RS04405	COG0028	Belongs to the TPP enzyme family
FIP56_RS04415	COG2308	Evidence 4 Homologs of previously reported genes of
FIP56_RS04430	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FIP56_RS04450	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FIP56_RS04455	COG2878	Part of a membrane complex involved in electron transport
FIP56_RS04460	COG2999	glutathione oxidoreductase activity
FIP56_RS04465	COG3104	oligopeptide transport
FIP56_RS04470	COG1528	Iron-storage protein
FIP56_RS04475	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FIP56_RS04480	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FIP56_RS04495	COG2271	Major facilitator Superfamily
FIP56_RS04505	COG1322	Protein conserved in bacteria
FIP56_RS04520	COG0679	Auxin Efflux Carrier
FIP56_RS04540	COG4948	Mandelate Racemase Muconate Lactonizing
FIP56_RS04570	COG2271	Major facilitator Superfamily
FIP56_RS04585	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FIP56_RS04595	COG4536	flavin adenine dinucleotide binding
FIP56_RS04610	COG0193	aminoacyl-tRNA hydrolase activity
FIP56_RS04625	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FIP56_RS04630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIP56_RS04635	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FIP56_RS04650	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FIP56_RS04675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FIP56_RS04685	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FIP56_RS04695	COG0095	Lipoate-protein ligase
FIP56_RS04700	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FIP56_RS04710	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FIP56_RS04730	COG1566	PFAM secretion protein HlyD family protein
FIP56_RS04770	COG0348	domain, Protein
FIP56_RS04805	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FIP56_RS04810	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FIP56_RS04815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FIP56_RS04825	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FIP56_RS04830	COG4535	Mg2 and Co2 transporter CorC
FIP56_RS04835	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FIP56_RS04845	COG1702	phosphate starvation-inducible protein PhoH
FIP56_RS04875	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FIP56_RS04880	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FIP56_RS04885	COG1214	PFAM Peptidase M22, glycoprotease
FIP56_RS04895	COG0436	Aminotransferase
FIP56_RS04900	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FIP56_RS04945	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FIP56_RS04960	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FIP56_RS04975	COG2814	Major facilitator Superfamily
FIP56_RS04980	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FIP56_RS04995	COG0148	phosphopyruvate hydratase activity
FIP56_RS05000	COG0415	Belongs to the DNA photolyase family
FIP56_RS05025	COG2264	protein methyltransferase activity
FIP56_RS05030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FIP56_RS05050	COG3676	manually curated
FIP56_RS05065	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FIP56_RS05085	COG0488	(ABC) transporter
FIP56_RS05090	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FIP56_RS05095	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FIP56_RS05115	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FIP56_RS05130	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FIP56_RS05145	COG0450	alkyl hydroperoxide reductase
FIP56_RS05155	COG2824	Alkylphosphonate utilization operon protein PhnA
FIP56_RS05180	COG1876	peptidase activity
FIP56_RS05200	COG0477	Major facilitator Superfamily
FIP56_RS05220	COG0156	8-amino-7-oxononanoate synthase activity
FIP56_RS05225	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FIP56_RS05255	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FIP56_RS05260	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FIP56_RS05265	COG0318	PFAM AMP-dependent synthetase and ligase
FIP56_RS05275	COG0512	Glutamine amidotransferase of anthranilate synthase
FIP56_RS05285	COG0667	Aldo Keto reductase
FIP56_RS05290	COG0667	Aldo Keto reductase
FIP56_RS05295	COG0667	Aldo Keto reductase
FIP56_RS05300	COG0667	Aldo Keto reductase
FIP56_RS05320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FIP56_RS05325	COG0601	transmembrane transport
FIP56_RS05330	COG4166	transmembrane transport
FIP56_RS05340	COG3550	peptidyl-serine autophosphorylation
FIP56_RS05345	COG1396	sequence-specific DNA binding
FIP56_RS05445	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FIP56_RS05465	COG0582	viral genome integration into host DNA
FIP56_RS05480	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FIP56_RS05480	COG0116	Belongs to the methyltransferase superfamily
FIP56_RS05495	COG0189	ligase activity
FIP56_RS05505	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FIP56_RS05515	COG1017	nitric oxide dioxygenase activity
FIP56_RS05515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FIP56_RS05520	COG1472	Belongs to the glycosyl hydrolase 3 family
FIP56_RS05530	COG1028	Short-chain dehydrogenase reductase Sdr
FIP56_RS05535	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FIP56_RS05545	COG0477	Major facilitator Superfamily
FIP56_RS05550	COG0489	protein tyrosine kinase activity
FIP56_RS05565	COG0668	transmembrane transport
FIP56_RS05575	COG0495	leucyl-tRNA aminoacylation
FIP56_RS05580	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FIP56_RS05585	COG1678	Uncharacterized ACR, COG1678
FIP56_RS05590	COG0494	nUDIX hydrolase
FIP56_RS05600	COG1472	Belongs to the glycosyl hydrolase 3 family
FIP56_RS05605	COG0833	amino acid
FIP56_RS05630	COG0719	Fe-S assembly protein
FIP56_RS05635	COG0396	ATPase activity
FIP56_RS05640	COG0719	Fe-S assembly protein
FIP56_RS05650	COG0569	domain protein
FIP56_RS05655	COG0531	amino acid
FIP56_RS05670	COG0730	response to heat
FIP56_RS05675	COG0708	Exodeoxyribonuclease III
FIP56_RS05680	COG1028	Short-chain dehydrogenase reductase Sdr
FIP56_RS05700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIP56_RS05725	COG0513	Belongs to the DEAD box helicase family
FIP56_RS05730	COG0302	gtp cyclohydrolase
FIP56_RS05735	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FIP56_RS05745	COG0179	Fumarylacetoacetate (FAA) hydrolase
FIP56_RS05750	COG0072	phenylalanine-tRNA ligase activity
FIP56_RS05750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FIP56_RS05760	COG0697	spore germination
FIP56_RS05765	COG3104	oligopeptide transport
FIP56_RS05770	COG2211	Major facilitator Superfamily
FIP56_RS05780	COG0246	Mannitol dehydrogenase
FIP56_RS05790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIP56_RS05795	COG0800	Aldolase
FIP56_RS05800	COG1904	glucuronate isomerase
FIP56_RS05805	COG2814	Major facilitator Superfamily
FIP56_RS05830	COG3655	Transcriptional regulator
FIP56_RS05855	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FIP56_RS05890	COG0813	purine-nucleoside phosphorylase activity
FIP56_RS05895	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FIP56_RS05905	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FIP56_RS05910	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FIP56_RS05930	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FIP56_RS05940	COG1137	ATPase activity
FIP56_RS05955	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FIP56_RS05960	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FIP56_RS05965	COG1686	Belongs to the peptidase S11 family
FIP56_RS05970	COG2921	Belongs to the UPF0250 family
FIP56_RS05985	COG0730	response to heat
FIP56_RS05995	COG0358	DNA primase activity
FIP56_RS06000	COG1610	YqeY-like protein
FIP56_RS06010	COG2027	D-alanyl-D-alanine carboxypeptidase
FIP56_RS06025	COG0037	tRNA processing
FIP56_RS06035	COG0142	geranyltranstransferase activity
FIP56_RS06050	COG0456	acetyltransferase
FIP56_RS06060	COG1187	pseudouridine synthase activity
FIP56_RS06070	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FIP56_RS06080	COG0359	binds to the 23S rRNA
FIP56_RS06110	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FIP56_RS06115	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FIP56_RS06130	COG0583	DNA-binding transcription factor activity
FIP56_RS06140	COG1012	belongs to the aldehyde dehydrogenase family
FIP56_RS06155	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FIP56_RS06160	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FIP56_RS06180	COG2974	May be involved in recombination
FIP56_RS06195	COG2996	Protein conserved in bacteria
FIP56_RS06205	COG0210	DNA helicase
FIP56_RS06210	COG0354	folic acid binding
FIP56_RS06220	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FIP56_RS06225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FIP56_RS06245	COG0210	DNA helicase
FIP56_RS06255	COG0799	negative regulation of ribosome biogenesis
FIP56_RS06275	COG2814	Major facilitator Superfamily
FIP56_RS06280	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIP56_RS06285	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FIP56_RS06290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FIP56_RS06295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIP56_RS06335	COG0535	radical SAM domain protein
FIP56_RS06350	COG2827	Endonuclease containing a URI domain
FIP56_RS06365	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FIP56_RS06365	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FIP56_RS06395	COG0386	Belongs to the glutathione peroxidase family
FIP56_RS06405	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FIP56_RS06420	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FIP56_RS06435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FIP56_RS06440	COG2814	Major facilitator Superfamily
FIP56_RS06445	COG2814	Major facilitator Superfamily
FIP56_RS06450	COG1085	galactose-1-phosphate uridylyltransferase
FIP56_RS06455	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FIP56_RS06475	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FIP56_RS06480	COG2835	tetraacyldisaccharide 4'-kinase activity
FIP56_RS06490	COG0482	sulfurtransferase activity
FIP56_RS06515	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FIP56_RS06520	COG2814	Major facilitator Superfamily
FIP56_RS06530	COG0751	glycine-tRNA ligase activity
FIP56_RS06535	COG0084	hydrolase, TatD family'
FIP56_RS06540	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FIP56_RS06590	COG1496	oxidoreductase activity
FIP56_RS06610	COG2814	Major facilitator Superfamily
FIP56_RS06615	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FIP56_RS06620	COG1823	symporter activity
FIP56_RS06625	COG4969	Belongs to the N-Me-Phe pilin family
FIP56_RS06640	COG1773	rubredoxin
FIP56_RS06645	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FIP56_RS06675	COG0405	Gamma-glutamyltransferase
FIP56_RS06685	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FIP56_RS06685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIP56_RS06690	COG1943	Transposase
FIP56_RS06695	COG2914	Belongs to the UPF0125 (RnfH) family
FIP56_RS06700	COG2867	negative regulation of translational initiation
FIP56_RS06705	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FIP56_RS06710	COG0037	tRNA processing
FIP56_RS06730	COG0140	phosphoribosyl-ATP diphosphatase activity
FIP56_RS06730	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FIP56_RS06735	COG0107	imidazoleglycerol-phosphate synthase activity
FIP56_RS06740	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FIP56_RS06750	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FIP56_RS06750	COG0131	Imidazoleglycerol-phosphate dehydratase
FIP56_RS06755	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FIP56_RS06760	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FIP56_RS06775	COG0477	Major facilitator Superfamily
FIP56_RS06800	COG1570	exodeoxyribonuclease VII activity
FIP56_RS06815	COG0477	Major facilitator Superfamily
FIP56_RS06830	COG0556	nucleotide-excision repair
FIP56_RS06835	COG2925	Exonuclease
FIP56_RS06845	COG4221	oxidoreductase activity
FIP56_RS06880	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FIP56_RS06885	COG2814	Major facilitator Superfamily
FIP56_RS06890	COG1741	Belongs to the pirin family
FIP56_RS06900	COG0028	Belongs to the TPP enzyme family
FIP56_RS06925	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FIP56_RS06940	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FIP56_RS06950	COG0509	glycine decarboxylation via glycine cleavage system
FIP56_RS06970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FIP56_RS06990	COG0477	Major facilitator Superfamily
FIP56_RS07020	COG1446	asparaginase
FIP56_RS07040	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FIP56_RS07045	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FIP56_RS07050	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FIP56_RS07050	COG0517	IMP dehydrogenase activity
FIP56_RS07060	COG1611	Belongs to the LOG family
FIP56_RS07070	COG2226	methyltransferase
FIP56_RS07090	COG0346	lactoylglutathione lyase activity
FIP56_RS07095	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FIP56_RS07105	COG0561	phosphatase activity
FIP56_RS07110	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FIP56_RS07115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIP56_RS07120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIP56_RS07125	COG3079	Belongs to the UPF0149 family
FIP56_RS07130	COG0517	IMP dehydrogenase activity
FIP56_RS07130	COG0516	GMP reductase activity
FIP56_RS07135	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FIP56_RS07140	COG0795	lipopolysaccharide-transporting ATPase activity
FIP56_RS07145	COG0795	lipopolysaccharide-transporting ATPase activity
FIP56_RS07160	COG0742	ribosomal rna small subunit methyltransferase
FIP56_RS07165	COG2860	membrane
FIP56_RS07180	COG0295	cytidine deaminase activity
FIP56_RS07190	COG2271	Major facilitator Superfamily
FIP56_RS07200	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FIP56_RS07205	COG4988	ABC transporter
FIP56_RS07230	COG1940	carbohydrate kinase activity
FIP56_RS07240	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FIP56_RS07250	COG0477	Major facilitator Superfamily
FIP56_RS07255	COG0277	FAD linked oxidase domain protein
FIP56_RS07255	COG0247	lactate metabolic process
FIP56_RS07275	COG0251	oxidation-reduction process
FIP56_RS07280	COG0659	secondary active sulfate transmembrane transporter activity
FIP56_RS07285	COG0842	Transport permease protein
FIP56_RS07290	COG1131	(ABC) transporter
FIP56_RS07300	COG0584	glycerophosphoryl diester phosphodiesterase
FIP56_RS07305	COG0584	glycerophosphoryl diester phosphodiesterase
FIP56_RS07310	COG2271	Major facilitator Superfamily
FIP56_RS07315	COG2027	D-alanyl-D-alanine carboxypeptidase
FIP56_RS07320	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FIP56_RS07325	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FIP56_RS07335	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FIP56_RS07340	COG0477	Major facilitator Superfamily
FIP56_RS07350	COG0534	Mate efflux family protein
FIP56_RS07360	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FIP56_RS07455	COG0191	fructose-bisphosphate aldolase activity
FIP56_RS07465	COG0126	phosphoglycerate kinase activity
FIP56_RS07485	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FIP56_RS07490	COG0416	fatty acid biosynthetic process
FIP56_RS07495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FIP56_RS07500	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FIP56_RS07505	COG1028	Short-chain dehydrogenase reductase Sdr
FIP56_RS07510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FIP56_RS07515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FIP56_RS07525	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FIP56_RS07525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FIP56_RS07535	COG2855	membrane
FIP56_RS07540	COG0483	inositol monophosphate 1-phosphatase activity
FIP56_RS07545	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FIP56_RS07545	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FIP56_RS07595	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FIP56_RS07600	COG1074	ATP-dependent DNA helicase activity
FIP56_RS07625	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FIP56_RS07645	COG0305	Participates in initiation and elongation during chromosome replication
FIP56_RS07650	COG2378	regulation of single-species biofilm formation
FIP56_RS07670	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FIP56_RS07690	COG0069	glutamate synthase activity
FIP56_RS07705	COG0814	amino acid
FIP56_RS07720	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FIP56_RS07795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIP56_RS07815	COG2166	iron-sulfur cluster assembly
FIP56_RS07840	COG0436	Aminotransferase
FIP56_RS07865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FIP56_RS07875	COG2983	Belongs to the UPF0260 family
FIP56_RS07885	COG1104	cysteine desulfurase activity
FIP56_RS07900	COG3453	Protein conserved in bacteria
FIP56_RS07900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FIP56_RS07905	COG0446	pyridine nucleotide-disulphide oxidoreductase
FIP56_RS07910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FIP56_RS07915	COG0640	Transcriptional regulator
FIP56_RS07920	COG1285	pathogenesis
FIP56_RS07935	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FIP56_RS07940	COG1280	lysine exporter protein (LysE YggA)
FIP56_RS07955	COG0842	Transport permease protein
FIP56_RS07960	COG1131	(ABC) transporter
FIP56_RS07965	COG0730	response to heat
FIP56_RS07975	COG0084	hydrolase, TatD family'
FIP56_RS07980	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FIP56_RS07995	COG0113	porphobilinogen synthase activity
FIP56_RS08005	COG0470	DNA polymerase III
FIP56_RS08010	COG0616	signal peptide processing
FIP56_RS08015	COG0625	glutathione transferase activity
FIP56_RS08020	COG2920	part of a sulfur-relay system
FIP56_RS08030	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FIP56_RS08035	COG0463	Glycosyl transferase, family 2
FIP56_RS08045	COG3394	polysaccharide catabolic process
FIP56_RS08050	COG0463	Glycosyl transferase, family 2
FIP56_RS08055	COG0772	Belongs to the SEDS family
FIP56_RS08070	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FIP56_RS08075	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FIP56_RS08080	COG3104	oligopeptide transport
FIP56_RS08085	COG0488	(ABC) transporter
FIP56_RS08100	COG2814	Major facilitator Superfamily
FIP56_RS08110	COG2814	Major facilitator Superfamily
FIP56_RS08115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FIP56_RS08120	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FIP56_RS08125	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FIP56_RS08140	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FIP56_RS08150	COG0460	homoserine dehydrogenase
FIP56_RS08150	COG0527	aspartate kinase activity
FIP56_RS08155	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FIP56_RS08165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FIP56_RS08185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FIP56_RS08195	COG1640	4-alpha-glucanotransferase
FIP56_RS08200	COG0058	SHG alpha-glucan phosphorylase activity
FIP56_RS08215	COG0033	Phosphoglucomutase
FIP56_RS08225	COG1523	belongs to the glycosyl hydrolase 13 family
FIP56_RS08275	COG0509	glycine decarboxylation via glycine cleavage system
FIP56_RS08280	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FIP56_RS08285	COG1982	Orn Lys Arg decarboxylase major
FIP56_RS08325	COG0242	peptide deformylase activity
FIP56_RS08345	COG0814	amino acid
FIP56_RS08350	COG1794	racemase activity, acting on amino acids and derivatives
FIP56_RS08355	COG0587	DNA-directed DNA polymerase activity
FIP56_RS08365	COG0668	transmembrane transport
FIP56_RS08375	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FIP56_RS08390	COG1196	nuclear chromosome segregation
FIP56_RS08390	COG0741	lytic transglycosylase activity
FIP56_RS08390	COG0739	heme binding
FIP56_RS08395	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FIP56_RS08400	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FIP56_RS08410	COG0024	Methionine aminopeptidase
FIP56_RS08420	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FIP56_RS08450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FIP56_RS08460	COG1051	belongs to the nudix hydrolase family
FIP56_RS08460	COG1056	cytidyltransferase-related domain
FIP56_RS08470	COG0688	phosphatidylethanolamine metabolic process
FIP56_RS08480	COG1994	Peptidase M50
FIP56_RS08530	COG1509	lysine 2,3-aminomutase activity
FIP56_RS08535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FIP56_RS08540	COG0508	dehydrogenase complex catalyzes the overall conversion of
FIP56_RS08555	COG0237	dephospho-CoA kinase activity
FIP56_RS08570	COG0180	Tryptophanyl-tRNA synthetase
FIP56_RS08620	COG0825	malonyl-CoA metabolic process
FIP56_RS08635	COG0814	amino acid
FIP56_RS08640	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FIP56_RS08665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FIP56_RS08680	COG0814	amino acid
FIP56_RS08705	COG0531	amino acid
FIP56_RS08720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FIP56_RS08725	COG2081	HI0933 family
FIP56_RS08745	COG1028	Short-chain dehydrogenase reductase Sdr
FIP56_RS08765	COG0459	protein refolding
FIP56_RS08775	COG0596	Alpha beta hydrolase
FIP56_RS08780	COG2814	Major facilitator Superfamily
FIP56_RS08795	COG2814	Major facilitator Superfamily
FIP56_RS08800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FIP56_RS08810	COG3022	response to hydroperoxide
FIP56_RS08825	COG0456	acetyltransferase
FIP56_RS08835	COG2814	Major facilitator Superfamily
FIP56_RS08840	COG2890	protein-(glutamine-N5) methyltransferase activity
FIP56_RS08845	COG0215	cysteine-tRNA ligase activity
FIP56_RS08865	COG2890	protein-(glutamine-N5) methyltransferase activity
FIP56_RS08885	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FIP56_RS08890	COG2814	Major facilitator Superfamily
FIP56_RS08900	COG0477	Major facilitator Superfamily
FIP56_RS08925	COG4221	oxidoreductase activity
FIP56_RS08950	COG4974	Belongs to the 'phage' integrase family
FIP56_RS08955	COG0335	large ribosomal subunit rRNA binding
FIP56_RS08960	COG0336	Belongs to the RNA methyltransferase TrmD family
FIP56_RS08965	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FIP56_RS09010	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FIP56_RS09015	COG0081	regulation of translation
FIP56_RS09020	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FIP56_RS09030	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FIP56_RS09040	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FIP56_RS09060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FIP56_RS09080	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FIP56_RS09090	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FIP56_RS09110	COG1566	PFAM secretion protein HlyD family protein
FIP56_RS09115	COG0210	DNA helicase
FIP56_RS09125	COG3104	oligopeptide transport
FIP56_RS09135	COG0552	protein localization to endoplasmic reticulum
FIP56_RS09155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FIP56_RS09160	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FIP56_RS09165	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FIP56_RS09175	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIP56_RS09175	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FIP56_RS09205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FIP56_RS09220	COG2095	MarC family integral membrane protein
FIP56_RS09240	COG1090	epimerase
FIP56_RS09245	COG1271	oxidase subunit
FIP56_RS09250	COG1294	oxidase, subunit
FIP56_RS09290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FIP56_RS09310	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FIP56_RS09315	COG0149	triose-phosphate isomerase activity
FIP56_RS09325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FIP56_RS09340	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FIP56_RS09345	COG1053	succinate dehydrogenase
FIP56_RS09350	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FIP56_RS09355	COG2009	succinate dehydrogenase
FIP56_RS09365	COG2223	nitrite transmembrane transporter activity
FIP56_RS09375	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FIP56_RS09380	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FIP56_RS09390	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FIP56_RS09400	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FIP56_RS09405	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FIP56_RS09440	COG0564	pseudouridine synthase activity
FIP56_RS09445	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FIP56_RS09460	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FIP56_RS09470	COG2251	uridine kinase activity
FIP56_RS09470	COG0195	Participates in both transcription termination and antitermination
FIP56_RS09485	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FIP56_RS09490	COG0606	chelatase, subunit chli
FIP56_RS09495	COG2960	long-chain fatty acid transporting porin activity
FIP56_RS09515	COG0713	ATP synthesis coupled electron transport
FIP56_RS09520	COG0839	Belongs to the complex I subunit 6 family
FIP56_RS09525	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIP56_RS09535	COG1034	ATP synthesis coupled electron transport
FIP56_RS09545	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FIP56_RS09550	COG0649	NAD binding
FIP56_RS09555	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIP56_RS09565	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FIP56_RS09575	COG0527	aspartate kinase activity
FIP56_RS09585	COG0076	glutamate decarboxylase activity
FIP56_RS09610	COG2814	Major facilitator Superfamily
FIP56_RS09640	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FIP56_RS09655	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FIP56_RS09690	COG0047	phosphoribosylformylglycinamidine synthase activity
FIP56_RS09690	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FIP56_RS09695	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FIP56_RS09705	COG0076	glutamate decarboxylase activity
FIP56_RS09715	COG1538	Outer membrane efflux protein
FIP56_RS09720	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FIP56_RS09725	COG0583	DNA-binding transcription factor activity
FIP56_RS09735	COG2814	Major facilitator Superfamily
FIP56_RS09755	COG0826	peptidase U32
FIP56_RS09770	COG4178	(ABC) transporter
FIP56_RS09775	COG0531	amino acid
FIP56_RS09780	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FIP56_RS09800	COG0814	amino acid
FIP56_RS09820	COG2205	protein histidine kinase activity
FIP56_RS09825	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FIP56_RS09840	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FIP56_RS09845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FIP56_RS09850	COG4558	Periplasmic binding protein
FIP56_RS09930	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FIP56_RS09935	COG0133	tryptophan synthase activity
FIP56_RS09950	COG3676	manually curated
FIP56_RS09970	COG0542	response to heat
FIP56_RS09985	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FIP56_RS10045	COG0477	Major facilitator Superfamily
FIP56_RS10050	COG0375	protein maturation
FIP56_RS10065	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FIP56_RS10075	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FIP56_RS10080	COG0298	carbon dioxide binding
FIP56_RS10105	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
FIP56_RS10115	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FIP56_RS10145	COG4753	response regulator
FIP56_RS10145	COG2207	Transcriptional regulator
FIP56_RS10165	COG0488	(ABC) transporter
FIP56_RS10170	COG3676	manually curated
FIP56_RS10190	COG2814	Major facilitator Superfamily
FIP56_RS10195	COG1309	transcriptional regulator
FIP56_RS10220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FIP56_RS10235	COG3676	manually curated
FIP56_RS10245	COG0308	aminopeptidase N
FIP56_RS10250	COG0071	Belongs to the small heat shock protein (HSP20) family
FIP56_RS10255	COG0134	indole-3-glycerol-phosphate synthase activity
FIP56_RS10255	COG0135	phosphoribosylanthranilate isomerase activity
FIP56_RS10265	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FIP56_RS10275	COG0512	Glutamine amidotransferase of anthranilate synthase
FIP56_RS10280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia