locus-tag	class	description
EGX27_RS00015	COG0833	amino acid
EGX27_RS00020	COG2945	thiolester hydrolase activity
EGX27_RS00025	COG1494	fructose-1,6-bisphosphatase
EGX27_RS00030	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGX27_RS00085	COG0456	acetyltransferase
EGX27_RS00090	COG2814	Major facilitator Superfamily
EGX27_RS00095	COG2890	protein-(glutamine-N5) methyltransferase activity
EGX27_RS00125	COG1619	proteins homologs of microcin C7 resistance protein MccF
EGX27_RS00145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX27_RS00150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX27_RS00175	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX27_RS00175	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX27_RS00185	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EGX27_RS00190	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EGX27_RS00195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGX27_RS00200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGX27_RS00220	COG0552	protein localization to endoplasmic reticulum
EGX27_RS00225	COG0210	DNA helicase
EGX27_RS00245	COG0601	transmembrane transport
EGX27_RS00255	COG0444	Belongs to the ABC transporter superfamily
EGX27_RS00260	COG4608	Belongs to the ABC transporter superfamily
EGX27_RS00265	COG2814	Major facilitator Superfamily
EGX27_RS00305	COG0583	DNA-binding transcription factor activity
EGX27_RS00320	COG2853	Lipoprotein
EGX27_RS00325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EGX27_RS00340	COG0531	amino acid
EGX27_RS00395	COG0488	(ABC) transporter
EGX27_RS00410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGX27_RS00415	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EGX27_RS00430	COG0772	Belongs to the SEDS family
EGX27_RS00440	COG0463	Glycosyl transferase, family 2
EGX27_RS00455	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EGX27_RS00465	COG2920	part of a sulfur-relay system
EGX27_RS00470	COG0625	glutathione transferase activity
EGX27_RS00475	COG0616	signal peptide processing
EGX27_RS00480	COG0470	DNA polymerase III
EGX27_RS00490	COG0113	porphobilinogen synthase activity
EGX27_RS00495	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EGX27_RS00500	COG0252	asparaginase activity
EGX27_RS00520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGX27_RS00530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EGX27_RS00545	COG0439	Biotin carboxylase
EGX27_RS00575	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EGX27_RS00575	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EGX27_RS00580	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EGX27_RS00590	COG0531	amino acid
EGX27_RS00605	COG1162	GTPase activity
EGX27_RS00620	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EGX27_RS00640	COG0492	ferredoxin-NADP+ reductase activity
EGX27_RS00650	COG0546	phosphoglycolate phosphatase activity
EGX27_RS00655	COG0583	DNA-binding transcription factor activity
EGX27_RS00660	COG2814	Major facilitator Superfamily
EGX27_RS00680	COG1446	asparaginase
EGX27_RS00695	COG0628	permease
EGX27_RS00710	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EGX27_RS00740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGX27_RS00770	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EGX27_RS00775	COG0318	PFAM AMP-dependent synthetase and ligase
EGX27_RS00775	COG0204	Acyl-transferase
EGX27_RS00785	COG3116	cell division
EGX27_RS00840	COG1940	carbohydrate kinase activity
EGX27_RS00860	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EGX27_RS00865	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EGX27_RS00870	COG0814	amino acid
EGX27_RS00880	COG0156	8-amino-7-oxononanoate synthase activity
EGX27_RS00910	COG0842	Transport permease protein
EGX27_RS00920	COG1131	(ABC) transporter
EGX27_RS00930	COG0584	glycerophosphoryl diester phosphodiesterase
EGX27_RS00935	COG2271	Major facilitator Superfamily
EGX27_RS00970	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EGX27_RS00985	COG0659	secondary active sulfate transmembrane transporter activity
EGX27_RS00990	COG0251	oxidation-reduction process
EGX27_RS01000	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EGX27_RS01005	COG4988	ABC transporter
EGX27_RS01025	COG1940	carbohydrate kinase activity
EGX27_RS01040	COG0247	lactate metabolic process
EGX27_RS01040	COG0277	FAD linked oxidase domain protein
EGX27_RS01050	COG0295	cytidine deaminase activity
EGX27_RS01055	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EGX27_RS01065	COG2860	membrane
EGX27_RS01070	COG0742	ribosomal rna small subunit methyltransferase
EGX27_RS01085	COG0795	lipopolysaccharide-transporting ATPase activity
EGX27_RS01090	COG0795	lipopolysaccharide-transporting ATPase activity
EGX27_RS01100	COG0516	GMP reductase activity
EGX27_RS01100	COG0517	IMP dehydrogenase activity
EGX27_RS01125	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EGX27_RS01145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGX27_RS01160	COG0813	purine-nucleoside phosphorylase activity
EGX27_RS01210	COG2814	Major facilitator Superfamily
EGX27_RS01215	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EGX27_RS01250	COG1611	Belongs to the LOG family
EGX27_RS01275	COG3220	belongs to the UPF0276 family
EGX27_RS01290	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EGX27_RS01290	COG0517	IMP dehydrogenase activity
EGX27_RS01295	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EGX27_RS01300	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EGX27_RS01305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EGX27_RS01315	COG1132	(ABC) transporter
EGX27_RS01330	COG3475	LICD family
EGX27_RS01335	COG1216	Glycosyl transferase, family 2
EGX27_RS01335	COG1442	glycosyl transferase family 8
EGX27_RS01340	COG1442	glycosyl transferase family 8
EGX27_RS01340	COG1216	Glycosyl transferase, family 2
EGX27_RS01345	COG0438	transferase activity, transferring glycosyl groups
EGX27_RS01365	COG1446	asparaginase
EGX27_RS01395	COG0477	Major facilitator Superfamily
EGX27_RS01415	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGX27_RS01435	COG0509	glycine decarboxylation via glycine cleavage system
EGX27_RS01510	COG1085	galactose-1-phosphate uridylyltransferase
EGX27_RS01515	COG2814	Major facilitator Superfamily
EGX27_RS01520	COG2814	Major facilitator Superfamily
EGX27_RS01525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGX27_RS01530	COG0513	Belongs to the DEAD box helicase family
EGX27_RS01540	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EGX27_RS01575	COG0386	Belongs to the glutathione peroxidase family
EGX27_RS01610	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EGX27_RS01610	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EGX27_RS01615	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EGX27_RS01690	COG1509	lysine 2,3-aminomutase activity
EGX27_RS01695	COG1278	Cold shock
EGX27_RS01725	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EGX27_RS01730	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGX27_RS01760	COG0084	hydrolase, TatD family'
EGX27_RS01765	COG0751	glycine-tRNA ligase activity
EGX27_RS01815	COG3104	oligopeptide transport
EGX27_RS01835	COG0077	Prephenate dehydratase
EGX27_RS01835	COG1605	Chorismate mutase
EGX27_RS01845	COG1760	l-serine dehydratase
EGX27_RS01850	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EGX27_RS01855	COG0316	Belongs to the HesB IscA family
EGX27_RS01860	COG2151	metal-sulfur cluster biosynthetic enzyme
EGX27_RS01870	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX27_RS01940	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EGX27_RS01945	COG0285	dihydrofolate synthase activity
EGX27_RS01950	COG0802	atpase or kinase
EGX27_RS01960	COG0728	peptidoglycan biosynthetic process
EGX27_RS01965	COG2918	glutathione biosynthetic process
EGX27_RS02010	COG0300	oxidoreductase activity
EGX27_RS02020	COG2081	HI0933 family
EGX27_RS02065	COG0189	ligase activity
EGX27_RS02075	COG1472	Belongs to the glycosyl hydrolase 3 family
EGX27_RS02115	COG0156	8-amino-7-oxononanoate synthase activity
EGX27_RS02125	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EGX27_RS02145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EGX27_RS02145	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EGX27_RS02150	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EGX27_RS02160	COG0512	Glutamine amidotransferase of anthranilate synthase
EGX27_RS02160	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EGX27_RS02165	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGX27_RS02165	COG0512	Glutamine amidotransferase of anthranilate synthase
EGX27_RS02175	COG0667	Aldo Keto reductase
EGX27_RS02195	COG0302	gtp cyclohydrolase
EGX27_RS02200	COG0513	Belongs to the DEAD box helicase family
EGX27_RS02205	COG3104	oligopeptide transport
EGX27_RS02220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX27_RS02235	COG1028	Short-chain dehydrogenase reductase Sdr
EGX27_RS02240	COG0708	Exodeoxyribonuclease III
EGX27_RS02260	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EGX27_RS02265	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EGX27_RS02290	COG0531	amino acid
EGX27_RS02295	COG0569	domain protein
EGX27_RS02305	COG0719	Fe-S assembly protein
EGX27_RS02310	COG0396	ATPase activity
EGX27_RS02315	COG0719	Fe-S assembly protein
EGX27_RS02350	COG0833	amino acid
EGX27_RS02420	COG0489	protein tyrosine kinase activity
EGX27_RS02430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGX27_RS02435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGX27_RS02450	COG0523	cobalamin synthesis protein
EGX27_RS02455	COG0735	belongs to the Fur family
EGX27_RS02460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGX27_RS02460	COG0072	phenylalanine-tRNA ligase activity
EGX27_RS02470	COG0697	spore germination
EGX27_RS02485	COG0583	DNA-binding transcription factor activity
EGX27_RS02505	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EGX27_RS02520	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EGX27_RS02590	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EGX27_RS02710	COG0738	Major facilitator superfamily
EGX27_RS02730	COG0191	fructose-bisphosphate aldolase activity
EGX27_RS02735	COG0469	pyruvate kinase activity
EGX27_RS02775	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EGX27_RS02780	COG1028	Short-chain dehydrogenase reductase Sdr
EGX27_RS02785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGX27_RS02790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGX27_RS02800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGX27_RS02800	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EGX27_RS02810	COG2855	membrane
EGX27_RS02815	COG0483	inositol monophosphate 1-phosphatase activity
EGX27_RS02850	COG1396	sequence-specific DNA binding
EGX27_RS02855	COG3550	peptidyl-serine autophosphorylation
EGX27_RS02890	COG2974	May be involved in recombination
EGX27_RS02900	COG2996	Protein conserved in bacteria
EGX27_RS02905	COG0210	DNA helicase
EGX27_RS02910	COG0354	folic acid binding
EGX27_RS02945	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGX27_RS02950	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EGX27_RS03005	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGX27_RS03010	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EGX27_RS03020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX27_RS03065	COG3655	Transcriptional regulator
EGX27_RS03085	COG1028	Short-chain dehydrogenase reductase Sdr
EGX27_RS03125	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EGX27_RS03130	COG0179	Fumarylacetoacetate (FAA) hydrolase
EGX27_RS03135	COG1137	ATPase activity
EGX27_RS03150	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EGX27_RS03155	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EGX27_RS03160	COG1686	Belongs to the peptidase S11 family
EGX27_RS03165	COG2921	Belongs to the UPF0250 family
EGX27_RS03195	COG0358	DNA primase activity
EGX27_RS03200	COG1610	YqeY-like protein
EGX27_RS03210	COG2027	D-alanyl-D-alanine carboxypeptidase
EGX27_RS03235	COG0142	geranyltranstransferase activity
EGX27_RS03295	COG1187	pseudouridine synthase activity
EGX27_RS03380	COG0583	DNA-binding transcription factor activity
EGX27_RS03390	COG1937	Protein conserved in bacteria
EGX27_RS03415	COG1876	peptidase activity
EGX27_RS03450	COG0450	alkyl hydroperoxide reductase
EGX27_RS03475	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EGX27_RS03505	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EGX27_RS03515	COG0488	(ABC) transporter
EGX27_RS03540	COG2852	Protein conserved in bacteria
EGX27_RS03550	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGX27_RS03555	COG2264	protein methyltransferase activity
EGX27_RS03560	COG1979	alcohol dehydrogenase
EGX27_RS03570	COG0277	FAD linked oxidase domain protein
EGX27_RS03575	COG3961	Belongs to the TPP enzyme family
EGX27_RS03590	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EGX27_RS03595	COG0095	Lipoate-protein ligase
EGX27_RS03605	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EGX27_RS03615	COG3104	oligopeptide transport
EGX27_RS03635	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EGX27_RS03655	COG0012	GTP binding
EGX27_RS03670	COG4536	flavin adenine dinucleotide binding
EGX27_RS03680	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EGX27_RS03740	COG0076	glutamate decarboxylase activity
EGX27_RS03775	COG2271	Major facilitator Superfamily
EGX27_RS03790	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EGX27_RS03800	COG1528	Iron-storage protein
EGX27_RS03810	COG2999	glutathione oxidoreductase activity
EGX27_RS03815	COG2878	Part of a membrane complex involved in electron transport
EGX27_RS03820	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGX27_RS03835	COG0670	Belongs to the BI1 family
EGX27_RS03840	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EGX27_RS03845	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EGX27_RS03865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EGX27_RS03885	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EGX27_RS03890	COG0330	HflC and HflK could
EGX27_RS03895	COG0330	HflC and HflK could
EGX27_RS03905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EGX27_RS03930	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EGX27_RS03935	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EGX27_RS03965	COG4122	O-methyltransferase activity
EGX27_RS03975	COG1702	phosphate starvation-inducible protein PhoH
EGX27_RS03985	COG4535	Mg2 and Co2 transporter CorC
EGX27_RS03990	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EGX27_RS04020	COG1496	oxidoreductase activity
EGX27_RS04075	COG2814	Major facilitator Superfamily
EGX27_RS04080	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EGX27_RS04085	COG1823	symporter activity
EGX27_RS04105	COG1773	rubredoxin
EGX27_RS04110	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EGX27_RS04120	COG0288	reversible hydration of carbon dioxide
EGX27_RS04125	COG0252	asparaginase activity
EGX27_RS04140	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EGX27_RS04145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EGX27_RS04155	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGX27_RS04160	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGX27_RS04165	COG1862	Preprotein translocase
EGX27_RS04175	COG1335	isochorismatase
EGX27_RS04220	COG1464	Belongs to the NlpA lipoprotein family
EGX27_RS04230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGX27_RS04240	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGX27_RS04240	COG1181	Belongs to the D-alanine--D-alanine ligase family
EGX27_RS04245	COG0189	ligase activity
EGX27_RS04245	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGX27_RS04260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EGX27_RS04325	COG1028	Short-chain dehydrogenase reductase Sdr
EGX27_RS04330	COG1028	Short-chain dehydrogenase reductase Sdr
EGX27_RS04350	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EGX27_RS04355	COG2814	Major facilitator Superfamily
EGX27_RS04360	COG0531	amino acid
EGX27_RS04370	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EGX27_RS04440	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EGX27_RS04445	COG0436	Aminotransferase
EGX27_RS04455	COG1214	PFAM Peptidase M22, glycoprotease
EGX27_RS04460	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EGX27_RS04465	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EGX27_RS04530	COG1217	gtp-binding protein TYPA
EGX27_RS04540	COG0405	Gamma-glutamyltransferase
EGX27_RS04550	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EGX27_RS04550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGX27_RS04555	COG2914	Belongs to the UPF0125 (RnfH) family
EGX27_RS04560	COG2867	negative regulation of translational initiation
EGX27_RS04610	COG2308	Evidence 4 Homologs of previously reported genes of
EGX27_RS04620	COG0477	Major facilitator Superfamily
EGX27_RS04635	COG0556	nucleotide-excision repair
EGX27_RS04640	COG2925	Exonuclease
EGX27_RS04645	COG4221	oxidoreductase activity
EGX27_RS04700	COG0346	lactoylglutathione lyase activity
EGX27_RS04705	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EGX27_RS04710	COG0561	phosphatase activity
EGX27_RS04730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGX27_RS04735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGX27_RS04740	COG3079	Belongs to the UPF0149 family
EGX27_RS04760	COG0586	Pfam SNARE associated Golgi protein
EGX27_RS04765	COG0586	Pfam SNARE associated Golgi protein
EGX27_RS04785	COG1530	ribonuclease E activity
EGX27_RS04800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EGX27_RS04845	COG3028	Belongs to the UPF0307 family
EGX27_RS04865	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGX27_RS04870	COG0564	pseudouridine synthase activity
EGX27_RS04875	COG2992	FlgJ-related protein
EGX27_RS04880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGX27_RS04885	COG1127	ABC transporter
EGX27_RS04905	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EGX27_RS04915	COG0318	PFAM AMP-dependent synthetase and ligase
EGX27_RS04925	COG0477	Major facilitator Superfamily
EGX27_RS04940	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EGX27_RS04965	COG3842	ATPase activity
EGX27_RS04970	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGX27_RS04975	COG1177	transmembrane transport
EGX27_RS05025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGX27_RS05030	COG1074	ATP-dependent DNA helicase activity
EGX27_RS05045	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EGX27_RS05050	COG0069	glutamate synthase activity
EGX27_RS05055	COG0697	spore germination
EGX27_RS05120	COG2166	iron-sulfur cluster assembly
EGX27_RS05190	COG2983	Belongs to the UPF0260 family
EGX27_RS05215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGX27_RS05245	COG1280	lysine exporter protein (LysE YggA)
EGX27_RS05255	COG0463	Glycosyl transferase, family 2
EGX27_RS05260	COG0842	Transport permease protein
EGX27_RS05265	COG1131	(ABC) transporter
EGX27_RS05275	COG0730	response to heat
EGX27_RS05280	COG0084	hydrolase, TatD family'
EGX27_RS05315	COG0248	Ppx GppA phosphatase
EGX27_RS05320	COG3118	belongs to the thioredoxin family
EGX27_RS05335	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EGX27_RS05335	COG0662	Cupin 2, conserved barrel domain protein
EGX27_RS05345	COG1088	dTDP-glucose 4,6-dehydratase activity
EGX27_RS05355	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EGX27_RS05360	COG1215	transferase activity, transferring glycosyl groups
EGX27_RS05380	COG0367	asparagine synthase
EGX27_RS05395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX27_RS05415	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EGX27_RS05420	COG1086	Polysaccharide biosynthesis protein
EGX27_RS05430	COG1643	Atp-dependent helicase
EGX27_RS05445	COG1393	Belongs to the ArsC family
EGX27_RS05450	COG0318	PFAM AMP-dependent synthetase and ligase
EGX27_RS05455	COG1960	acyl-CoA dehydrogenase activity
EGX27_RS05460	COG1250	3-hydroxyacyl-CoA dehydrogenase
EGX27_RS05460	COG1024	Enoyl-CoA hydratase
EGX27_RS05465	COG0183	Belongs to the thiolase family
EGX27_RS05475	COG2814	Major facilitator Superfamily
EGX27_RS05565	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGX27_RS05590	COG0557	exoribonuclease II activity
EGX27_RS05605	COG0681	Belongs to the peptidase S26 family
EGX27_RS05615	COG2828	Protein conserved in bacteria
EGX27_RS05620	COG2828	Protein conserved in bacteria
EGX27_RS05625	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EGX27_RS05630	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EGX27_RS05635	COG1519	Transferase
EGX27_RS05640	COG0142	geranyltranstransferase activity
EGX27_RS05645	COG1183	phosphatidylcholine synthase activity
EGX27_RS05660	COG1472	Belongs to the glycosyl hydrolase 3 family
EGX27_RS05680	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGX27_RS05700	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGX27_RS05745	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EGX27_RS05755	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EGX27_RS05775	COG0850	regulation of cytokinetic process
EGX27_RS05790	COG1127	ABC transporter
EGX27_RS05795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGX27_RS05800	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGX27_RS05830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX27_RS05835	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGX27_RS05840	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EGX27_RS05880	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EGX27_RS05890	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EGX27_RS05905	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EGX27_RS05915	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EGX27_RS05925	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGX27_RS05935	COG1640	4-alpha-glucanotransferase
EGX27_RS05940	COG0058	SHG alpha-glucan phosphorylase activity
EGX27_RS05955	COG0033	Phosphoglucomutase
EGX27_RS05965	COG1523	belongs to the glycosyl hydrolase 13 family
EGX27_RS05985	COG0509	glycine decarboxylation via glycine cleavage system
EGX27_RS05995	COG1982	Orn Lys Arg decarboxylase major
EGX27_RS06015	COG0242	peptide deformylase activity
EGX27_RS06020	COG0587	DNA-directed DNA polymerase activity
EGX27_RS06045	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EGX27_RS06060	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EGX27_RS06065	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EGX27_RS06105	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EGX27_RS06115	COG1051	belongs to the nudix hydrolase family
EGX27_RS06115	COG1056	cytidyltransferase-related domain
EGX27_RS06135	COG1994	Peptidase M50
EGX27_RS06195	COG2271	Major facilitator Superfamily
EGX27_RS06200	COG1739	Uncharacterized protein family UPF0029
EGX27_RS06230	COG0281	malic enzyme
EGX27_RS06235	COG0196	riboflavin kinase activity
EGX27_RS06270	COG0519	Catalyzes the synthesis of GMP from XMP
EGX27_RS06270	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EGX27_RS06275	COG1475	DNA binding
EGX27_RS06280	COG1192	Involved in chromosome partitioning
EGX27_RS06320	COG0339	signal peptide processing
EGX27_RS06350	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EGX27_RS06355	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EGX27_RS06365	COG2226	methyltransferase
EGX27_RS06370	COG1040	competence protein
EGX27_RS06380	COG0537	adenosine 5'-monophosphoramidase activity
EGX27_RS06385	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EGX27_RS06400	COG0837	glucose binding
EGX27_RS06410	COG2917	probably involved in intracellular septation
EGX27_RS06415	COG0009	L-threonylcarbamoyladenylate synthase
EGX27_RS06435	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EGX27_RS06445	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EGX27_RS06455	COG0671	phosphoesterase, PA-phosphatase related
EGX27_RS06460	COG4969	Belongs to the N-Me-Phe pilin family
EGX27_RS06475	COG0497	DNA recombination
EGX27_RS06485	COG0436	Aminotransferase
EGX27_RS06500	COG0833	amino acid
EGX27_RS06515	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGX27_RS06515	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGX27_RS06595	COG1704	LemA family
EGX27_RS06640	COG2363	Small membrane protein
EGX27_RS06670	COG0385	Bile acid
EGX27_RS06735	COG0811	peptide transport
EGX27_RS06745	COG1183	phosphatidylcholine synthase activity
EGX27_RS06750	COG4401	Chorismate mutase type I
EGX27_RS06805	COG1051	belongs to the nudix hydrolase family
EGX27_RS06820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX27_RS06825	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGX27_RS06840	COG0237	dephospho-CoA kinase activity
EGX27_RS06855	COG0180	Tryptophanyl-tRNA synthetase
EGX27_RS06890	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EGX27_RS06935	COG0814	amino acid
EGX27_RS06940	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EGX27_RS06965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGX27_RS06980	COG0814	amino acid
EGX27_RS06995	COG0531	amino acid
EGX27_RS07005	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EGX27_RS07010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX27_RS07015	COG0398	Pfam SNARE associated Golgi protein
EGX27_RS07020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGX27_RS07030	COG0531	amino acid
EGX27_RS07050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EGX27_RS07115	COG0201	protein transport
EGX27_RS07240	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EGX27_RS07250	COG0575	Belongs to the CDS family
EGX27_RS07255	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EGX27_RS07280	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EGX27_RS07295	COG0531	amino acid
EGX27_RS07315	COG0114	fumarate hydratase activity
EGX27_RS07350	COG0525	valine-tRNA ligase activity
EGX27_RS07365	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EGX27_RS07380	COG2304	oxidoreductase activity
EGX27_RS07400	COG0714	Associated with various cellular activities
EGX27_RS07410	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EGX27_RS07430	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EGX27_RS07440	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EGX27_RS07445	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EGX27_RS07450	COG2814	Major facilitator Superfamily
EGX27_RS07455	COG1271	oxidase subunit
EGX27_RS07460	COG1294	oxidase, subunit
EGX27_RS07470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX27_RS07475	COG2814	Major facilitator Superfamily
EGX27_RS07490	COG0589	response to stress
EGX27_RS07515	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EGX27_RS07525	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EGX27_RS07540	COG0594	ribonuclease P activity
EGX27_RS07555	COG1560	Kdo2-lipid A biosynthetic process
EGX27_RS07560	COG1560	Kdo2-lipid A biosynthetic process
EGX27_RS07610	COG1984	allophanate hydrolase subunit 2
EGX27_RS07670	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EGX27_RS07685	COG1116	anion transmembrane transporter activity
EGX27_RS07730	COG0557	exoribonuclease II activity
EGX27_RS07760	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EGX27_RS07770	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGX27_RS07770	COG0574	Belongs to the PEP-utilizing enzyme family
EGX27_RS07910	COG0738	Major facilitator superfamily
EGX27_RS07925	COG3201	nicotinamide mononucleotide transporter
EGX27_RS07950	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EGX27_RS07975	COG0542	response to heat
EGX27_RS08005	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EGX27_RS08015	COG0204	Acyl-transferase
EGX27_RS08055	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGX27_RS08055	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGX27_RS08065	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGX27_RS08065	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGX27_RS08075	COG0242	peptide deformylase activity
EGX27_RS08100	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGX27_RS08105	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EGX27_RS08115	COG2814	Major facilitator Superfamily
EGX27_RS08140	COG0814	amino acid
EGX27_RS08150	COG0778	Nitroreductase
EGX27_RS08170	COG1621	beta-fructofuranosidase activity
EGX27_RS08185	COG0287	Prephenate dehydrogenase
EGX27_RS08185	COG1605	Chorismate mutase
EGX27_RS08190	COG1605	Chorismate mutase
EGX27_RS08190	COG0287	Prephenate dehydrogenase
EGX27_RS08225	COG0583	DNA-binding transcription factor activity
EGX27_RS08235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX27_RS08280	COG0505	Belongs to the CarA family
EGX27_RS08285	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EGX27_RS08290	COG0540	Belongs to the ATCase OTCase family
EGX27_RS08305	COG0814	amino acid
EGX27_RS08360	COG0857	belongs to the CobB CobQ family
EGX27_RS08360	COG0280	phosphate acetyltransferase
EGX27_RS08370	COG0629	single-stranded DNA binding
EGX27_RS08375	COG2137	regulation of response to DNA damage stimulus
EGX27_RS08390	COG0425	Belongs to the sulfur carrier protein TusA family
EGX27_RS08390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGX27_RS08425	COG0477	Major facilitator Superfamily
EGX27_RS08460	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EGX27_RS08465	COG0512	Glutamine amidotransferase of anthranilate synthase
EGX27_RS08490	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGX27_RS08500	COG0134	indole-3-glycerol-phosphate synthase activity
EGX27_RS08500	COG0135	phosphoribosylanthranilate isomerase activity
EGX27_RS08505	COG0071	Belongs to the small heat shock protein (HSP20) family
EGX27_RS08510	COG0308	aminopeptidase N
EGX27_RS08555	COG0488	(ABC) transporter
EGX27_RS08575	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EGX27_RS08585	COG1295	ribonuclease BN
EGX27_RS08610	COG1121	(ABC) transporter
EGX27_RS08635	COG0138	bifunctional purine biosynthesis protein purh
EGX27_RS08670	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EGX27_RS08690	COG0658	competence protein
EGX27_RS08690	COG2333	competence protein COMEC
EGX27_RS08695	COG0204	Acyl-transferase
EGX27_RS08705	COG0009	L-threonylcarbamoyladenylate synthase
EGX27_RS08725	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EGX27_RS08745	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EGX27_RS08755	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EGX27_RS08765	COG2862	Uncharacterized protein family, UPF0114
EGX27_RS08775	COG2066	Belongs to the glutaminase family
EGX27_RS08790	COG3040	lipid binding
EGX27_RS08800	COG0814	amino acid
EGX27_RS08825	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EGX27_RS08865	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EGX27_RS08895	COG0814	amino acid
EGX27_RS08905	COG0531	amino acid
EGX27_RS08915	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EGX27_RS08925	COG0826	peptidase U32
EGX27_RS08935	COG1538	Outer membrane efflux protein
EGX27_RS08950	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EGX27_RS08955	COG0047	phosphoribosylformylglycinamidine synthase activity
EGX27_RS08955	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EGX27_RS08995	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EGX27_RS09015	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EGX27_RS09045	COG2814	Major facilitator Superfamily
EGX27_RS09050	COG0019	diaminopimelate decarboxylase activity
EGX27_RS09055	COG2814	Major facilitator Superfamily
EGX27_RS09060	COG4264	IucA IucC family
EGX27_RS09070	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGX27_RS09090	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EGX27_RS09100	COG1034	ATP synthesis coupled electron transport
EGX27_RS09115	COG0839	Belongs to the complex I subunit 6 family
EGX27_RS09170	COG2251	uridine kinase activity
EGX27_RS09170	COG0195	Participates in both transcription termination and antitermination
EGX27_RS09195	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EGX27_RS09200	COG0564	pseudouridine synthase activity
EGX27_RS09260	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EGX27_RS09275	COG2223	nitrite transmembrane transporter activity
EGX27_RS09290	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EGX27_RS09295	COG1053	succinate dehydrogenase
EGX27_RS09330	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EGX27_RS09355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGX27_RS09390	COG1294	oxidase, subunit
EGX27_RS09400	COG1090	epimerase
EGX27_RS09445	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EGX27_RS09460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGX27_RS09490	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EGX27_RS09570	COG4974	Belongs to the 'phage' integrase family
EGX27_RS09605	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGX27_RS09615	COG2814	Major facilitator Superfamily
EGX27_RS09620	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGX27_RS09640	COG2890	protein-(glutamine-N5) methyltransferase activity
EGX27_RS09690	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EGX27_RS09715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA