locus-tag	class	description
F92_RS00015	COG0477	Major facilitator Superfamily
F92_RS00020	COG3335	DDE superfamily endonuclease
F92_RS00035	COG3961	Belongs to the TPP enzyme family
F92_RS00055	COG0425	Belongs to the sulfur carrier protein TusA family
F92_RS00055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F92_RS00070	COG2137	regulation of response to DNA damage stimulus
F92_RS00075	COG0629	single-stranded DNA binding
F92_RS00085	COG0857	belongs to the CobB CobQ family
F92_RS00085	COG0280	phosphate acetyltransferase
F92_RS00095	COG3335	DDE superfamily endonuclease
F92_RS00130	COG3335	DDE superfamily endonuclease
F92_RS00135	COG0814	amino acid
F92_RS00150	COG0540	Belongs to the ATCase OTCase family
F92_RS00155	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F92_RS00160	COG0505	Belongs to the CarA family
F92_RS00205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F92_RS00215	COG0583	DNA-binding transcription factor activity
F92_RS00250	COG0287	Prephenate dehydrogenase
F92_RS00250	COG1605	Chorismate mutase
F92_RS00255	COG1605	Chorismate mutase
F92_RS00255	COG0287	Prephenate dehydrogenase
F92_RS00270	COG1621	beta-fructofuranosidase activity
F92_RS00275	COG3335	DDE superfamily endonuclease
F92_RS00295	COG0778	Nitroreductase
F92_RS00305	COG0814	amino acid
F92_RS00330	COG2814	Major facilitator Superfamily
F92_RS00340	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
F92_RS00345	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F92_RS00370	COG0242	peptide deformylase activity
F92_RS00380	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F92_RS00380	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F92_RS00390	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F92_RS00390	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F92_RS00400	COG3335	DDE superfamily endonuclease
F92_RS00435	COG0204	Acyl-transferase
F92_RS00445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
F92_RS00470	COG0542	response to heat
F92_RS00495	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
F92_RS00520	COG3201	nicotinamide mononucleotide transporter
F92_RS00530	COG3335	DDE superfamily endonuclease
F92_RS00535	COG0738	Major facilitator superfamily
F92_RS00665	COG3335	DDE superfamily endonuclease
F92_RS00680	COG0574	Belongs to the PEP-utilizing enzyme family
F92_RS00680	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F92_RS00685	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
F92_RS00695	COG3335	DDE superfamily endonuclease
F92_RS00720	COG0557	exoribonuclease II activity
F92_RS00765	COG1116	anion transmembrane transporter activity
F92_RS00780	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F92_RS00810	COG3335	DDE superfamily endonuclease
F92_RS00845	COG1984	allophanate hydrolase subunit 2
F92_RS00870	COG3335	DDE superfamily endonuclease
F92_RS00885	COG0589	response to stress
F92_RS00910	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
F92_RS00920	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F92_RS00935	COG0594	ribonuclease P activity
F92_RS00950	COG1560	Kdo2-lipid A biosynthetic process
F92_RS00955	COG1560	Kdo2-lipid A biosynthetic process
F92_RS00985	COG3335	DDE superfamily endonuclease
F92_RS00990	COG2814	Major facilitator Superfamily
F92_RS00995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F92_RS01005	COG1294	oxidase, subunit
F92_RS01010	COG1271	oxidase subunit
F92_RS01015	COG2814	Major facilitator Superfamily
F92_RS01020	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F92_RS01025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F92_RS01035	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F92_RS01055	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
F92_RS01065	COG0714	Associated with various cellular activities
F92_RS01085	COG2304	oxidoreductase activity
F92_RS01100	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
F92_RS01115	COG0525	valine-tRNA ligase activity
F92_RS01135	COG1304	FMN binding
F92_RS01150	COG0114	fumarate hydratase activity
F92_RS01170	COG0531	amino acid
F92_RS01185	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
F92_RS01210	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F92_RS01215	COG0575	Belongs to the CDS family
F92_RS01225	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F92_RS01350	COG0201	protein transport
F92_RS01390	COG3335	DDE superfamily endonuclease
F92_RS01400	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F92_RS01420	COG0531	amino acid
F92_RS01430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F92_RS01435	COG0398	Pfam SNARE associated Golgi protein
F92_RS01440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F92_RS01445	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F92_RS01455	COG0531	amino acid
F92_RS01480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F92_RS01505	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
F92_RS01510	COG0814	amino acid
F92_RS01555	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
F92_RS01590	COG0180	Tryptophanyl-tRNA synthetase
F92_RS01605	COG0237	dephospho-CoA kinase activity
F92_RS01620	COG0508	dehydrogenase complex catalyzes the overall conversion of
F92_RS01625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F92_RS01635	COG3335	DDE superfamily endonuclease
F92_RS01640	COG1051	belongs to the nudix hydrolase family
F92_RS01695	COG4401	Chorismate mutase type I
F92_RS01710	COG0811	peptide transport
F92_RS01745	COG0456	acetyltransferase
F92_RS01755	COG3335	DDE superfamily endonuclease
F92_RS01765	COG0415	Belongs to the DNA photolyase family
F92_RS01770	COG0415	Belongs to the DNA photolyase family
F92_RS01775	COG3046	protein related to deoxyribodipyrimidine photolyase
F92_RS01785	COG0385	Bile acid
F92_RS01815	COG2363	Small membrane protein
F92_RS01820	COG3335	DDE superfamily endonuclease
F92_RS01870	COG1704	LemA family
F92_RS01950	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F92_RS01950	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F92_RS01965	COG0833	amino acid
F92_RS01980	COG0436	Aminotransferase
F92_RS01990	COG0497	DNA recombination
F92_RS02010	COG4969	Belongs to the N-Me-Phe pilin family
F92_RS02015	COG0671	phosphoesterase, PA-phosphatase related
F92_RS02025	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
F92_RS02035	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F92_RS02055	COG0009	L-threonylcarbamoyladenylate synthase
F92_RS02060	COG2917	probably involved in intracellular septation
F92_RS02070	COG0837	glucose binding
F92_RS02085	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F92_RS02090	COG0537	adenosine 5'-monophosphoramidase activity
F92_RS02100	COG1040	competence protein
F92_RS02105	COG2226	methyltransferase
F92_RS02115	COG0812	UDP-N-acetylmuramate dehydrogenase activity
F92_RS02120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F92_RS02150	COG0339	signal peptide processing
F92_RS02190	COG1192	Involved in chromosome partitioning
F92_RS02195	COG1475	DNA binding
F92_RS02200	COG0519	Catalyzes the synthesis of GMP from XMP
F92_RS02200	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F92_RS02235	COG0196	riboflavin kinase activity
F92_RS02270	COG1739	Uncharacterized protein family UPF0029
F92_RS02275	COG2271	Major facilitator Superfamily
F92_RS02335	COG1994	Peptidase M50
F92_RS02355	COG1051	belongs to the nudix hydrolase family
F92_RS02355	COG1056	cytidyltransferase-related domain
F92_RS02365	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F92_RS02405	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F92_RS02410	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F92_RS02425	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
F92_RS02450	COG0587	DNA-directed DNA polymerase activity
F92_RS02455	COG0242	peptide deformylase activity
F92_RS02475	COG1982	Orn Lys Arg decarboxylase major
F92_RS02485	COG0509	glycine decarboxylation via glycine cleavage system
F92_RS02505	COG1523	belongs to the glycosyl hydrolase 13 family
F92_RS02515	COG0033	Phosphoglucomutase
F92_RS02530	COG0058	SHG alpha-glucan phosphorylase activity
F92_RS02545	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F92_RS02555	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F92_RS02565	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F92_RS02575	COG0083	homoserine kinase activity
F92_RS02580	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F92_RS02585	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
F92_RS02610	COG3335	DDE superfamily endonuclease
F92_RS02630	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
F92_RS02635	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F92_RS02640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F92_RS02645	COG3335	DDE superfamily endonuclease
F92_RS02675	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F92_RS02680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F92_RS02685	COG1127	ABC transporter
F92_RS02700	COG0850	regulation of cytokinetic process
F92_RS02730	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F92_RS02780	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F92_RS02800	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F92_RS02820	COG1472	Belongs to the glycosyl hydrolase 3 family
F92_RS02835	COG1183	phosphatidylcholine synthase activity
F92_RS02840	COG0142	geranyltranstransferase activity
F92_RS02845	COG1519	Transferase
F92_RS02850	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
F92_RS02855	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F92_RS02860	COG2828	Protein conserved in bacteria
F92_RS02865	COG2828	Protein conserved in bacteria
F92_RS02875	COG0681	Belongs to the peptidase S26 family
F92_RS02890	COG0557	exoribonuclease II activity
F92_RS02915	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F92_RS03020	COG2814	Major facilitator Superfamily
F92_RS03030	COG0183	Belongs to the thiolase family
F92_RS03040	COG1960	acyl-CoA dehydrogenase activity
F92_RS03045	COG0318	PFAM AMP-dependent synthetase and ligase
F92_RS03050	COG1393	Belongs to the ArsC family
F92_RS03065	COG1643	Atp-dependent helicase
F92_RS03075	COG1086	Polysaccharide biosynthesis protein
F92_RS03080	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F92_RS03100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F92_RS03115	COG0367	asparagine synthase
F92_RS03135	COG1215	transferase activity, transferring glycosyl groups
F92_RS03140	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
F92_RS03145	COG1088	dTDP-glucose 4,6-dehydratase activity
F92_RS03155	COG3335	DDE superfamily endonuclease
F92_RS03160	COG0662	Cupin 2, conserved barrel domain protein
F92_RS03160	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
F92_RS03175	COG3118	belongs to the thioredoxin family
F92_RS03180	COG0248	Ppx GppA phosphatase
F92_RS03195	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F92_RS03220	COG0084	hydrolase, TatD family'
F92_RS03230	COG0730	response to heat
F92_RS03240	COG1131	(ABC) transporter
F92_RS03245	COG0842	Transport permease protein
F92_RS03250	COG0463	Glycosyl transferase, family 2
F92_RS03260	COG1280	lysine exporter protein (LysE YggA)
F92_RS03280	COG3335	DDE superfamily endonuclease
F92_RS03295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F92_RS03320	COG2983	Belongs to the UPF0260 family
F92_RS03390	COG2166	iron-sulfur cluster assembly
F92_RS03455	COG0697	spore germination
F92_RS03460	COG0069	glutamate synthase activity
F92_RS03465	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
F92_RS03480	COG1074	ATP-dependent DNA helicase activity
F92_RS03485	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F92_RS03525	COG3335	DDE superfamily endonuclease
F92_RS03535	COG1177	transmembrane transport
F92_RS03540	COG1176	ABC-type spermidine putrescine transport system, permease component I
F92_RS03545	COG3842	ATPase activity
F92_RS03550	COG3335	DDE superfamily endonuclease
F92_RS03565	COG0655	NAD(P)H dehydrogenase (quinone) activity
F92_RS03575	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
F92_RS03590	COG0477	Major facilitator Superfamily
F92_RS03600	COG0318	PFAM AMP-dependent synthetase and ligase
F92_RS03610	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F92_RS03630	COG1127	ABC transporter
F92_RS03635	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F92_RS03640	COG2992	FlgJ-related protein
F92_RS03645	COG0564	pseudouridine synthase activity
F92_RS03650	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F92_RS03670	COG3028	Belongs to the UPF0307 family
F92_RS03715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F92_RS03730	COG1530	ribonuclease E activity
F92_RS03750	COG0586	Pfam SNARE associated Golgi protein
F92_RS03755	COG0586	Pfam SNARE associated Golgi protein
F92_RS03770	COG3079	Belongs to the UPF0149 family
F92_RS03775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F92_RS03780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F92_RS03795	COG0561	phosphatase activity
F92_RS03805	COG0346	lactoylglutathione lyase activity
F92_RS03820	COG3335	DDE superfamily endonuclease
F92_RS03825	COG3590	peptidase
F92_RS03870	COG4221	oxidoreductase activity
F92_RS03875	COG2925	Exonuclease
F92_RS03880	COG0556	nucleotide-excision repair
F92_RS03895	COG0477	Major facilitator Superfamily
F92_RS03920	COG1473	amidohydrolase
F92_RS03955	COG2867	negative regulation of translational initiation
F92_RS03960	COG2914	Belongs to the UPF0125 (RnfH) family
F92_RS03965	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
F92_RS03965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F92_RS03975	COG0405	Gamma-glutamyltransferase
F92_RS03985	COG1217	gtp-binding protein TYPA
F92_RS04030	COG3335	DDE superfamily endonuclease
F92_RS04045	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
F92_RS04050	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F92_RS04055	COG1214	PFAM Peptidase M22, glycoprotease
F92_RS04065	COG0436	Aminotransferase
F92_RS04070	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F92_RS04140	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
F92_RS04150	COG0531	amino acid
F92_RS04155	COG2814	Major facilitator Superfamily
F92_RS04160	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F92_RS04175	COG1028	Short-chain dehydrogenase reductase Sdr
F92_RS04235	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F92_RS04250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F92_RS04250	COG0189	ligase activity
F92_RS04255	COG1181	Belongs to the D-alanine--D-alanine ligase family
F92_RS04255	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F92_RS04265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F92_RS04275	COG0814	amino acid
F92_RS04280	COG1464	Belongs to the NlpA lipoprotein family
F92_RS04335	COG1862	Preprotein translocase
F92_RS04340	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F92_RS04345	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F92_RS04355	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F92_RS04360	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F92_RS04375	COG0252	asparaginase activity
F92_RS04380	COG0288	reversible hydration of carbon dioxide
F92_RS04390	COG2515	1-aminocyclopropane-1-carboxylate deaminase
F92_RS04395	COG1773	rubredoxin
F92_RS04415	COG1823	symporter activity
F92_RS04420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F92_RS04480	COG1496	oxidoreductase activity
F92_RS04510	COG0815	Transfers the fatty acyl group on membrane lipoproteins
F92_RS04515	COG4535	Mg2 and Co2 transporter CorC
F92_RS04525	COG1702	phosphate starvation-inducible protein PhoH
F92_RS04535	COG4122	O-methyltransferase activity
F92_RS04565	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
F92_RS04570	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F92_RS04595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F92_RS04605	COG0330	HflC and HflK could
F92_RS04610	COG0330	HflC and HflK could
F92_RS04615	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F92_RS04630	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F92_RS04640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F92_RS04660	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
F92_RS04665	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F92_RS04670	COG0670	Belongs to the BI1 family
F92_RS04685	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F92_RS04690	COG2878	Part of a membrane complex involved in electron transport
F92_RS04695	COG2999	glutathione oxidoreductase activity
F92_RS04705	COG1528	Iron-storage protein
F92_RS04715	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
F92_RS04730	COG2271	Major facilitator Superfamily
F92_RS04765	COG0076	glutamate decarboxylase activity
F92_RS04825	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F92_RS04835	COG4536	flavin adenine dinucleotide binding
F92_RS04850	COG0012	GTP binding
F92_RS04870	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
F92_RS04885	COG3104	oligopeptide transport
F92_RS04895	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
F92_RS04910	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F92_RS04920	COG3335	DDE superfamily endonuclease
F92_RS04935	COG3961	Belongs to the TPP enzyme family
F92_RS04940	COG0277	FAD linked oxidase domain protein
F92_RS04950	COG1979	alcohol dehydrogenase
F92_RS04955	COG2264	protein methyltransferase activity
F92_RS04960	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F92_RS04965	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
F92_RS04970	COG2852	Protein conserved in bacteria
F92_RS04995	COG0488	(ABC) transporter
F92_RS05005	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F92_RS05035	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F92_RS05045	COG3335	DDE superfamily endonuclease
F92_RS05050	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F92_RS05065	COG0450	alkyl hydroperoxide reductase
F92_RS05105	COG1876	peptidase activity
F92_RS05120	COG1012	belongs to the aldehyde dehydrogenase family
F92_RS05130	COG1937	Protein conserved in bacteria
F92_RS05140	COG0583	DNA-binding transcription factor activity
F92_RS05175	COG3335	DDE superfamily endonuclease
F92_RS05230	COG1187	pseudouridine synthase activity
F92_RS05290	COG0142	geranyltranstransferase activity
F92_RS05315	COG2027	D-alanyl-D-alanine carboxypeptidase
F92_RS05325	COG1610	YqeY-like protein
F92_RS05330	COG0358	DNA primase activity
F92_RS05360	COG2921	Belongs to the UPF0250 family
F92_RS05365	COG1686	Belongs to the peptidase S11 family
F92_RS05370	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F92_RS05375	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
F92_RS05390	COG1137	ATPase activity
F92_RS05395	COG0179	Fumarylacetoacetate (FAA) hydrolase
F92_RS05400	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
F92_RS05440	COG1028	Short-chain dehydrogenase reductase Sdr
F92_RS05460	COG3655	Transcriptional regulator
F92_RS05500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F92_RS05510	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
F92_RS05515	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F92_RS05580	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
F92_RS05585	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F92_RS05615	COG0354	folic acid binding
F92_RS05620	COG0210	DNA helicase
F92_RS05625	COG2996	Protein conserved in bacteria
F92_RS05635	COG2974	May be involved in recombination
F92_RS05670	COG3550	peptidyl-serine autophosphorylation
F92_RS05675	COG1396	sequence-specific DNA binding
F92_RS05685	COG3335	DDE superfamily endonuclease
F92_RS05710	COG0483	inositol monophosphate 1-phosphatase activity
F92_RS05715	COG2855	membrane
F92_RS05735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F92_RS05740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F92_RS05745	COG1028	Short-chain dehydrogenase reductase Sdr
F92_RS05750	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F92_RS05790	COG0469	pyruvate kinase activity
F92_RS05795	COG0191	fructose-bisphosphate aldolase activity
F92_RS05800	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
F92_RS05815	COG0738	Major facilitator superfamily
F92_RS05935	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
F92_RS05950	COG0583	DNA-binding transcription factor activity
F92_RS06010	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F92_RS06025	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
F92_RS06045	COG0583	DNA-binding transcription factor activity
F92_RS06060	COG3335	DDE superfamily endonuclease
F92_RS06075	COG0072	phenylalanine-tRNA ligase activity
F92_RS06075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F92_RS06080	COG0735	belongs to the Fur family
F92_RS06085	COG0523	cobalamin synthesis protein
F92_RS06100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F92_RS06105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F92_RS06115	COG0489	protein tyrosine kinase activity
F92_RS06180	COG0833	amino acid
F92_RS06215	COG0719	Fe-S assembly protein
F92_RS06220	COG0396	ATPase activity
F92_RS06225	COG0719	Fe-S assembly protein
F92_RS06235	COG0569	domain protein
F92_RS06240	COG0531	amino acid
F92_RS06270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F92_RS06275	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F92_RS06280	COG3335	DDE superfamily endonuclease
F92_RS06300	COG0708	Exodeoxyribonuclease III
F92_RS06305	COG1028	Short-chain dehydrogenase reductase Sdr
F92_RS06320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F92_RS06335	COG3104	oligopeptide transport
F92_RS06340	COG0513	Belongs to the DEAD box helicase family
F92_RS06345	COG0302	gtp cyclohydrolase
F92_RS06370	COG0667	Aldo Keto reductase
F92_RS06375	COG2271	Major facilitator Superfamily
F92_RS06385	COG0512	Glutamine amidotransferase of anthranilate synthase
F92_RS06385	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F92_RS06390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F92_RS06390	COG0512	Glutamine amidotransferase of anthranilate synthase
F92_RS06400	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F92_RS06405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F92_RS06405	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F92_RS06425	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F92_RS06435	COG0156	8-amino-7-oxononanoate synthase activity
F92_RS06450	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
F92_RS06450	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
F92_RS06470	COG1028	Short-chain dehydrogenase reductase Sdr
F92_RS06480	COG1472	Belongs to the glycosyl hydrolase 3 family
F92_RS06490	COG0189	ligase activity
F92_RS06525	COG3335	DDE superfamily endonuclease
F92_RS06535	COG2081	HI0933 family
F92_RS06545	COG0300	oxidoreductase activity
F92_RS06565	COG3335	DDE superfamily endonuclease
F92_RS06595	COG2918	glutathione biosynthetic process
F92_RS06600	COG0728	peptidoglycan biosynthetic process
F92_RS06610	COG0802	atpase or kinase
F92_RS06615	COG0285	dihydrofolate synthase activity
F92_RS06620	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
F92_RS06635	COG1288	antiporter activity
F92_RS06640	COG1288	antiporter activity
F92_RS06715	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F92_RS06725	COG2151	metal-sulfur cluster biosynthetic enzyme
F92_RS06730	COG0316	Belongs to the HesB IscA family
F92_RS06735	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F92_RS06740	COG1760	l-serine dehydratase
F92_RS06750	COG0077	Prephenate dehydratase
F92_RS06750	COG1605	Chorismate mutase
F92_RS06770	COG3104	oligopeptide transport
F92_RS06815	COG0751	glycine-tRNA ligase activity
F92_RS06845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F92_RS06860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F92_RS06890	COG1278	Cold shock
F92_RS06895	COG1509	lysine 2,3-aminomutase activity
F92_RS06930	COG3335	DDE superfamily endonuclease
F92_RS06975	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
F92_RS06980	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F92_RS06980	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F92_RS07010	COG0386	Belongs to the glutathione peroxidase family
F92_RS07050	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
F92_RS07060	COG0513	Belongs to the DEAD box helicase family
F92_RS07065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F92_RS07070	COG2814	Major facilitator Superfamily
F92_RS07075	COG2814	Major facilitator Superfamily
F92_RS07080	COG1085	galactose-1-phosphate uridylyltransferase
F92_RS07110	COG3335	DDE superfamily endonuclease
F92_RS07150	COG3397	chitin binding
F92_RS07160	COG0509	glycine decarboxylation via glycine cleavage system
F92_RS07180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F92_RS07200	COG0477	Major facilitator Superfamily
F92_RS07230	COG1446	asparaginase
F92_RS07250	COG0438	transferase activity, transferring glycosyl groups
F92_RS07255	COG1442	glycosyl transferase family 8
F92_RS07255	COG1216	Glycosyl transferase, family 2
F92_RS07260	COG1442	glycosyl transferase family 8
F92_RS07260	COG1216	Glycosyl transferase, family 2
F92_RS07280	COG1132	(ABC) transporter
F92_RS07290	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F92_RS07295	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F92_RS07300	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F92_RS07305	COG0517	IMP dehydrogenase activity
F92_RS07305	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F92_RS07320	COG3220	belongs to the UPF0276 family
F92_RS07345	COG1611	Belongs to the LOG family
F92_RS07375	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
F92_RS07380	COG2814	Major facilitator Superfamily
F92_RS07425	COG0813	purine-nucleoside phosphorylase activity
F92_RS07430	COG3335	DDE superfamily endonuclease
F92_RS07445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F92_RS07465	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F92_RS07490	COG0517	IMP dehydrogenase activity
F92_RS07490	COG0516	GMP reductase activity
F92_RS07500	COG0795	lipopolysaccharide-transporting ATPase activity
F92_RS07505	COG0795	lipopolysaccharide-transporting ATPase activity
F92_RS07520	COG0742	ribosomal rna small subunit methyltransferase
F92_RS07525	COG2860	membrane
F92_RS07535	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
F92_RS07540	COG0295	cytidine deaminase activity
F92_RS07550	COG0247	lactate metabolic process
F92_RS07550	COG0277	FAD linked oxidase domain protein
F92_RS07565	COG1940	carbohydrate kinase activity
F92_RS07585	COG4988	ABC transporter
F92_RS07590	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F92_RS07600	COG0251	oxidation-reduction process
F92_RS07605	COG0659	secondary active sulfate transmembrane transporter activity
F92_RS07620	COG0232	Belongs to the dGTPase family. Type 2 subfamily
F92_RS07630	COG3335	DDE superfamily endonuclease
F92_RS07650	COG2271	Major facilitator Superfamily
F92_RS07655	COG0584	glycerophosphoryl diester phosphodiesterase
F92_RS07665	COG1131	(ABC) transporter
F92_RS07700	COG0156	8-amino-7-oxononanoate synthase activity
F92_RS07710	COG0814	amino acid
F92_RS07715	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
F92_RS07720	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
F92_RS07740	COG1940	carbohydrate kinase activity
F92_RS07795	COG3116	cell division
F92_RS07805	COG0318	PFAM AMP-dependent synthetase and ligase
F92_RS07805	COG0204	Acyl-transferase
F92_RS07810	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
F92_RS07820	COG3335	DDE superfamily endonuclease
F92_RS07845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F92_RS07875	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F92_RS07900	COG1446	asparaginase
F92_RS07920	COG2814	Major facilitator Superfamily
F92_RS07925	COG0583	DNA-binding transcription factor activity
F92_RS07930	COG0546	phosphoglycolate phosphatase activity
F92_RS07940	COG0492	ferredoxin-NADP+ reductase activity
F92_RS07960	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
F92_RS07975	COG1162	GTPase activity
F92_RS07990	COG0531	amino acid
F92_RS08000	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F92_RS08005	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
F92_RS08005	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
F92_RS08035	COG0439	Biotin carboxylase
F92_RS08050	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F92_RS08060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F92_RS08080	COG0252	asparaginase activity
F92_RS08085	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F92_RS08090	COG0113	porphobilinogen synthase activity
F92_RS08100	COG0470	DNA polymerase III
F92_RS08105	COG0616	signal peptide processing
F92_RS08110	COG0625	glutathione transferase activity
F92_RS08115	COG2920	part of a sulfur-relay system
F92_RS08125	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F92_RS08130	COG3335	DDE superfamily endonuclease
F92_RS08140	COG0463	Glycosyl transferase, family 2
F92_RS08150	COG0772	Belongs to the SEDS family
F92_RS08165	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
F92_RS08170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F92_RS08185	COG0488	(ABC) transporter
F92_RS08220	COG3335	DDE superfamily endonuclease
F92_RS08230	COG3335	DDE superfamily endonuclease
F92_RS08255	COG0583	DNA-binding transcription factor activity
F92_RS08275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F92_RS08290	COG0531	amino acid
F92_RS08310	COG3335	DDE superfamily endonuclease
F92_RS08330	COG2814	Major facilitator Superfamily
F92_RS08335	COG0444	Belongs to the ABC transporter superfamily
F92_RS08350	COG4166	transmembrane transport
F92_RS08365	COG0210	DNA helicase
F92_RS08370	COG0552	protein localization to endoplasmic reticulum
F92_RS08390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F92_RS08395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F92_RS08400	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
F92_RS08405	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
F92_RS08415	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F92_RS08415	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F92_RS08440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F92_RS08445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F92_RS08465	COG1619	proteins homologs of microcin C7 resistance protein MccF
F92_RS08485	COG3335	DDE superfamily endonuclease
F92_RS08500	COG2890	protein-(glutamine-N5) methyltransferase activity
F92_RS08505	COG2814	Major facilitator Superfamily
F92_RS08510	COG0456	acetyltransferase
F92_RS08520	COG3335	DDE superfamily endonuclease
F92_RS08575	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F92_RS08580	COG1494	fructose-1,6-bisphosphatase
F92_RS08585	COG2945	thiolester hydrolase activity
F92_RS08590	COG0833	amino acid
F92_RS08600	COG1674	ftsk spoiiie
F92_RS08615	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F92_RS08640	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
F92_RS08650	COG3335	DDE superfamily endonuclease
F92_RS08680	COG3335	DDE superfamily endonuclease
F92_RS08695	COG2890	protein-(glutamine-N5) methyltransferase activity
F92_RS08715	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F92_RS08720	COG2814	Major facilitator Superfamily
F92_RS08730	COG3023	N-Acetylmuramoyl-L-alanine amidase
F92_RS08765	COG4974	Belongs to the 'phage' integrase family
F92_RS08845	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F92_RS08875	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F92_RS08890	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F92_RS08905	COG3335	DDE superfamily endonuclease
F92_RS08930	COG1090	epimerase
F92_RS08940	COG1271	oxidase subunit
F92_RS08945	COG1294	oxidase, subunit
F92_RS08955	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
F92_RS08990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F92_RS09015	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F92_RS09050	COG1053	succinate dehydrogenase
F92_RS09070	COG2223	nitrite transmembrane transporter activity
F92_RS09085	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F92_RS09145	COG0564	pseudouridine synthase activity
F92_RS09150	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F92_RS09175	COG2251	uridine kinase activity
F92_RS09175	COG0195	Participates in both transcription termination and antitermination
F92_RS09200	COG3335	DDE superfamily endonuclease
F92_RS09235	COG0839	Belongs to the complex I subunit 6 family
F92_RS09250	COG1034	ATP synthesis coupled electron transport
F92_RS09260	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
F92_RS09280	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F92_RS09290	COG4264	IucA IucC family
F92_RS09295	COG2814	Major facilitator Superfamily
F92_RS09300	COG0019	diaminopimelate decarboxylase activity
F92_RS09305	COG2814	Major facilitator Superfamily
F92_RS09340	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F92_RS09360	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F92_RS09410	COG0047	phosphoribosylformylglycinamidine synthase activity
F92_RS09410	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F92_RS09415	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
F92_RS09430	COG1538	Outer membrane efflux protein
F92_RS09440	COG0826	peptidase U32
F92_RS09450	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F92_RS09475	COG0814	amino acid
F92_RS09505	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
F92_RS09530	COG3335	DDE superfamily endonuclease
F92_RS09550	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
F92_RS09565	COG3335	DDE superfamily endonuclease
F92_RS09580	COG3040	lipid binding
F92_RS09595	COG2066	Belongs to the glutaminase family
F92_RS09605	COG2862	Uncharacterized protein family, UPF0114
F92_RS09610	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
F92_RS09620	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F92_RS09640	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F92_RS09660	COG0009	L-threonylcarbamoyladenylate synthase
F92_RS09670	COG0204	Acyl-transferase
F92_RS09675	COG0658	competence protein
F92_RS09675	COG2333	competence protein COMEC
F92_RS09685	COG1181	Belongs to the D-alanine--D-alanine ligase family
F92_RS09720	COG3335	DDE superfamily endonuclease
F92_RS09730	COG3293	Transposase
F92_RS09740	COG0138	bifunctional purine biosynthesis protein purh
F92_RS09765	COG1121	(ABC) transporter
F92_RS09800	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F92_RS09810	COG3335	DDE superfamily endonuclease
F92_RS09820	COG0488	(ABC) transporter
F92_RS09865	COG0308	aminopeptidase N
F92_RS09870	COG0071	Belongs to the small heat shock protein (HSP20) family
F92_RS09875	COG0134	indole-3-glycerol-phosphate synthase activity
F92_RS09875	COG0135	phosphoribosylanthranilate isomerase activity
F92_RS09885	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F92_RS09915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia