locus-tag	class	description
FTS_RS00015	COG0477	Major facilitator Superfamily
FTS_RS00030	COG3961	Belongs to the TPP enzyme family
FTS_RS00050	COG0425	Belongs to the sulfur carrier protein TusA family
FTS_RS00050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FTS_RS00065	COG2137	regulation of response to DNA damage stimulus
FTS_RS00070	COG0629	single-stranded DNA binding
FTS_RS00080	COG0857	belongs to the CobB CobQ family
FTS_RS00080	COG0280	phosphate acetyltransferase
FTS_RS00090	COG3335	DDE superfamily endonuclease
FTS_RS00125	COG3335	DDE superfamily endonuclease
FTS_RS00130	COG0814	amino acid
FTS_RS00145	COG0540	Belongs to the ATCase OTCase family
FTS_RS00150	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FTS_RS00155	COG0505	Belongs to the CarA family
FTS_RS00200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FTS_RS00210	COG0583	DNA-binding transcription factor activity
FTS_RS00235	COG0284	orotidine-5'-phosphate decarboxylase activity
FTS_RS00245	COG1605	Chorismate mutase
FTS_RS00245	COG0287	Prephenate dehydrogenase
FTS_RS00250	COG0287	Prephenate dehydrogenase
FTS_RS00250	COG1605	Chorismate mutase
FTS_RS00265	COG1621	beta-fructofuranosidase activity
FTS_RS00270	COG1621	beta-fructofuranosidase activity
FTS_RS00275	COG3335	DDE superfamily endonuclease
FTS_RS00295	COG0778	Nitroreductase
FTS_RS00305	COG0814	amino acid
FTS_RS00330	COG2814	Major facilitator Superfamily
FTS_RS00340	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FTS_RS00345	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FTS_RS00370	COG0242	peptide deformylase activity
FTS_RS00380	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FTS_RS00380	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FTS_RS00390	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FTS_RS00390	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FTS_RS00400	COG3335	DDE superfamily endonuclease
FTS_RS00435	COG0204	Acyl-transferase
FTS_RS00445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FTS_RS00470	COG0542	response to heat
FTS_RS00495	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FTS_RS00520	COG3201	nicotinamide mononucleotide transporter
FTS_RS00530	COG3335	DDE superfamily endonuclease
FTS_RS00535	COG0738	Major facilitator superfamily
FTS_RS00665	COG3335	DDE superfamily endonuclease
FTS_RS00680	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FTS_RS00680	COG0574	Belongs to the PEP-utilizing enzyme family
FTS_RS00685	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FTS_RS00695	COG3335	DDE superfamily endonuclease
FTS_RS00720	COG0557	exoribonuclease II activity
FTS_RS00765	COG1116	anion transmembrane transporter activity
FTS_RS00780	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FTS_RS00810	COG3335	DDE superfamily endonuclease
FTS_RS00845	COG1984	allophanate hydrolase subunit 2
FTS_RS00870	COG3335	DDE superfamily endonuclease
FTS_RS00885	COG0589	response to stress
FTS_RS00910	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FTS_RS00920	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FTS_RS00935	COG0594	ribonuclease P activity
FTS_RS00950	COG1560	Kdo2-lipid A biosynthetic process
FTS_RS00955	COG1560	Kdo2-lipid A biosynthetic process
FTS_RS00985	COG3335	DDE superfamily endonuclease
FTS_RS00990	COG2814	Major facilitator Superfamily
FTS_RS00995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FTS_RS01005	COG1294	oxidase, subunit
FTS_RS01010	COG1271	oxidase subunit
FTS_RS01015	COG2814	Major facilitator Superfamily
FTS_RS01020	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FTS_RS01025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FTS_RS01035	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FTS_RS01055	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FTS_RS01065	COG0714	Associated with various cellular activities
FTS_RS01085	COG2304	oxidoreductase activity
FTS_RS01100	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FTS_RS01115	COG0525	valine-tRNA ligase activity
FTS_RS01135	COG1304	FMN binding
FTS_RS01150	COG0114	fumarate hydratase activity
FTS_RS01170	COG0531	amino acid
FTS_RS01185	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FTS_RS01210	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FTS_RS01215	COG0575	Belongs to the CDS family
FTS_RS01225	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FTS_RS01350	COG0201	protein transport
FTS_RS01400	COG3335	DDE superfamily endonuclease
FTS_RS01415	COG3335	DDE superfamily endonuclease
FTS_RS01425	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FTS_RS01445	COG0531	amino acid
FTS_RS01455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FTS_RS01460	COG0398	Pfam SNARE associated Golgi protein
FTS_RS01465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FTS_RS01470	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FTS_RS01480	COG0531	amino acid
FTS_RS01495	COG0814	amino acid
FTS_RS01505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FTS_RS01530	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FTS_RS01535	COG0814	amino acid
FTS_RS01615	COG0180	Tryptophanyl-tRNA synthetase
FTS_RS01630	COG0237	dephospho-CoA kinase activity
FTS_RS01645	COG0508	dehydrogenase complex catalyzes the overall conversion of
FTS_RS01650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FTS_RS01660	COG3335	DDE superfamily endonuclease
FTS_RS01665	COG1051	belongs to the nudix hydrolase family
FTS_RS01720	COG4401	Chorismate mutase type I
FTS_RS01725	COG1183	phosphatidylcholine synthase activity
FTS_RS01735	COG0811	peptide transport
FTS_RS01770	COG0456	acetyltransferase
FTS_RS01780	COG3335	DDE superfamily endonuclease
FTS_RS01790	COG0415	Belongs to the DNA photolyase family
FTS_RS01795	COG0415	Belongs to the DNA photolyase family
FTS_RS01800	COG3046	protein related to deoxyribodipyrimidine photolyase
FTS_RS01810	COG0385	Bile acid
FTS_RS01840	COG2363	Small membrane protein
FTS_RS01845	COG3335	DDE superfamily endonuclease
FTS_RS01895	COG1704	LemA family
FTS_RS01975	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FTS_RS01975	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FTS_RS01990	COG0833	amino acid
FTS_RS02005	COG0436	Aminotransferase
FTS_RS02015	COG0497	DNA recombination
FTS_RS02035	COG4969	Belongs to the N-Me-Phe pilin family
FTS_RS02040	COG0671	phosphoesterase, PA-phosphatase related
FTS_RS02050	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FTS_RS02060	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FTS_RS02080	COG0009	L-threonylcarbamoyladenylate synthase
FTS_RS02085	COG2917	probably involved in intracellular septation
FTS_RS02095	COG0837	glucose binding
FTS_RS02110	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FTS_RS02115	COG0537	adenosine 5'-monophosphoramidase activity
FTS_RS02125	COG1040	competence protein
FTS_RS02130	COG2226	methyltransferase
FTS_RS02140	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FTS_RS02145	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FTS_RS02175	COG0339	signal peptide processing
FTS_RS02215	COG1192	Involved in chromosome partitioning
FTS_RS02220	COG1475	DNA binding
FTS_RS02225	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FTS_RS02225	COG0519	Catalyzes the synthesis of GMP from XMP
FTS_RS02260	COG0196	riboflavin kinase activity
FTS_RS02265	COG0281	malic enzyme
FTS_RS02285	COG3335	DDE superfamily endonuclease
FTS_RS02300	COG1739	Uncharacterized protein family UPF0029
FTS_RS02305	COG2271	Major facilitator Superfamily
FTS_RS02365	COG1994	Peptidase M50
FTS_RS02385	COG1051	belongs to the nudix hydrolase family
FTS_RS02385	COG1056	cytidyltransferase-related domain
FTS_RS02395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FTS_RS02435	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FTS_RS02440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FTS_RS02455	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FTS_RS02485	COG0587	DNA-directed DNA polymerase activity
FTS_RS02490	COG0242	peptide deformylase activity
FTS_RS02510	COG1982	Orn Lys Arg decarboxylase major
FTS_RS02520	COG0509	glycine decarboxylation via glycine cleavage system
FTS_RS02540	COG1523	belongs to the glycosyl hydrolase 13 family
FTS_RS02550	COG0033	Phosphoglucomutase
FTS_RS02565	COG0058	SHG alpha-glucan phosphorylase activity
FTS_RS02570	COG1640	4-alpha-glucanotransferase
FTS_RS02580	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FTS_RS02590	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FTS_RS02600	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FTS_RS02615	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FTS_RS02620	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FTS_RS02645	COG3335	DDE superfamily endonuclease
FTS_RS02665	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FTS_RS02670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FTS_RS02675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FTS_RS02680	COG3335	DDE superfamily endonuclease
FTS_RS02710	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FTS_RS02715	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FTS_RS02720	COG1127	ABC transporter
FTS_RS02735	COG0850	regulation of cytokinetic process
FTS_RS02755	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FTS_RS02765	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FTS_RS02815	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FTS_RS02835	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FTS_RS02855	COG1472	Belongs to the glycosyl hydrolase 3 family
FTS_RS02870	COG1183	phosphatidylcholine synthase activity
FTS_RS02875	COG0142	geranyltranstransferase activity
FTS_RS02880	COG1519	Transferase
FTS_RS02885	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FTS_RS02890	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FTS_RS02895	COG2828	Protein conserved in bacteria
FTS_RS02905	COG0681	Belongs to the peptidase S26 family
FTS_RS02920	COG0557	exoribonuclease II activity
FTS_RS02945	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FTS_RS02965	COG5002	protein histidine kinase activity
FTS_RS03055	COG0183	Belongs to the thiolase family
FTS_RS03060	COG1024	Enoyl-CoA hydratase
FTS_RS03060	COG1250	3-hydroxyacyl-CoA dehydrogenase
FTS_RS03065	COG1960	acyl-CoA dehydrogenase activity
FTS_RS03070	COG0318	PFAM AMP-dependent synthetase and ligase
FTS_RS03075	COG1393	Belongs to the ArsC family
FTS_RS03090	COG1643	Atp-dependent helicase
FTS_RS03100	COG1086	Polysaccharide biosynthesis protein
FTS_RS03105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FTS_RS03125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FTS_RS03140	COG0367	asparagine synthase
FTS_RS03160	COG1215	transferase activity, transferring glycosyl groups
FTS_RS03165	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FTS_RS03170	COG1088	dTDP-glucose 4,6-dehydratase activity
FTS_RS03180	COG3335	DDE superfamily endonuclease
FTS_RS03185	COG0662	Cupin 2, conserved barrel domain protein
FTS_RS03185	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FTS_RS03200	COG3118	belongs to the thioredoxin family
FTS_RS03205	COG0248	Ppx GppA phosphatase
FTS_RS03220	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FTS_RS03245	COG0084	hydrolase, TatD family'
FTS_RS03255	COG0730	response to heat
FTS_RS03265	COG1131	(ABC) transporter
FTS_RS03270	COG0842	Transport permease protein
FTS_RS03275	COG0463	Glycosyl transferase, family 2
FTS_RS03285	COG1280	lysine exporter protein (LysE YggA)
FTS_RS03305	COG3335	DDE superfamily endonuclease
FTS_RS03320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FTS_RS03345	COG2983	Belongs to the UPF0260 family
FTS_RS03415	COG2166	iron-sulfur cluster assembly
FTS_RS03480	COG0697	spore germination
FTS_RS03485	COG0069	glutamate synthase activity
FTS_RS03490	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FTS_RS03505	COG1074	ATP-dependent DNA helicase activity
FTS_RS03510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FTS_RS03550	COG3335	DDE superfamily endonuclease
FTS_RS03560	COG1177	transmembrane transport
FTS_RS03565	COG1176	ABC-type spermidine putrescine transport system, permease component I
FTS_RS03570	COG3842	ATPase activity
FTS_RS03575	COG3335	DDE superfamily endonuclease
FTS_RS03590	COG0655	NAD(P)H dehydrogenase (quinone) activity
FTS_RS03600	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FTS_RS03615	COG0477	Major facilitator Superfamily
FTS_RS03625	COG0318	PFAM AMP-dependent synthetase and ligase
FTS_RS03635	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FTS_RS03655	COG1127	ABC transporter
FTS_RS03660	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FTS_RS03665	COG2992	FlgJ-related protein
FTS_RS03670	COG0564	pseudouridine synthase activity
FTS_RS03675	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FTS_RS03695	COG3028	Belongs to the UPF0307 family
FTS_RS03740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FTS_RS03755	COG1530	ribonuclease E activity
FTS_RS03775	COG0586	Pfam SNARE associated Golgi protein
FTS_RS03780	COG0586	Pfam SNARE associated Golgi protein
FTS_RS03795	COG3079	Belongs to the UPF0149 family
FTS_RS03800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FTS_RS03805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FTS_RS03820	COG0561	phosphatase activity
FTS_RS03825	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FTS_RS03830	COG0346	lactoylglutathione lyase activity
FTS_RS03845	COG3335	DDE superfamily endonuclease
FTS_RS03850	COG3590	peptidase
FTS_RS03895	COG4221	oxidoreductase activity
FTS_RS03900	COG2925	Exonuclease
FTS_RS03905	COG0556	nucleotide-excision repair
FTS_RS03920	COG0477	Major facilitator Superfamily
FTS_RS03945	COG1473	amidohydrolase
FTS_RS03980	COG2867	negative regulation of translational initiation
FTS_RS03985	COG2914	Belongs to the UPF0125 (RnfH) family
FTS_RS03990	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FTS_RS03990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FTS_RS04000	COG0405	Gamma-glutamyltransferase
FTS_RS04010	COG1217	gtp-binding protein TYPA
FTS_RS04045	COG0732	type I restriction modification DNA specificity domain
FTS_RS04060	COG3335	DDE superfamily endonuclease
FTS_RS04080	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FTS_RS04085	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FTS_RS04090	COG1214	PFAM Peptidase M22, glycoprotease
FTS_RS04100	COG0436	Aminotransferase
FTS_RS04105	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FTS_RS04175	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FTS_RS04185	COG0531	amino acid
FTS_RS04190	COG2814	Major facilitator Superfamily
FTS_RS04195	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FTS_RS04215	COG1028	Short-chain dehydrogenase reductase Sdr
FTS_RS04275	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FTS_RS04290	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FTS_RS04290	COG0189	ligase activity
FTS_RS04295	COG1181	Belongs to the D-alanine--D-alanine ligase family
FTS_RS04295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FTS_RS04305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FTS_RS04315	COG0814	amino acid
FTS_RS04320	COG1464	Belongs to the NlpA lipoprotein family
FTS_RS04355	COG0583	DNA-binding transcription factor activity
FTS_RS04365	COG1335	isochorismatase
FTS_RS04375	COG1862	Preprotein translocase
FTS_RS04380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FTS_RS04385	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FTS_RS04395	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FTS_RS04400	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FTS_RS04415	COG0252	asparaginase activity
FTS_RS04420	COG0288	reversible hydration of carbon dioxide
FTS_RS04430	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FTS_RS04435	COG1773	rubredoxin
FTS_RS04455	COG1823	symporter activity
FTS_RS04460	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FTS_RS04465	COG2814	Major facilitator Superfamily
FTS_RS04520	COG1496	oxidoreductase activity
FTS_RS04550	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FTS_RS04555	COG4535	Mg2 and Co2 transporter CorC
FTS_RS04565	COG1702	phosphate starvation-inducible protein PhoH
FTS_RS04575	COG4122	O-methyltransferase activity
FTS_RS04605	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FTS_RS04610	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FTS_RS04635	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FTS_RS04645	COG0330	HflC and HflK could
FTS_RS04650	COG0330	HflC and HflK could
FTS_RS04655	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FTS_RS04670	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FTS_RS04680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FTS_RS04700	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FTS_RS04705	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FTS_RS04710	COG0670	Belongs to the BI1 family
FTS_RS04725	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FTS_RS04730	COG2878	Part of a membrane complex involved in electron transport
FTS_RS04735	COG2999	glutathione oxidoreductase activity
FTS_RS04745	COG1528	Iron-storage protein
FTS_RS04755	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FTS_RS04805	COG0076	glutamate decarboxylase activity
FTS_RS04865	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FTS_RS04875	COG4536	flavin adenine dinucleotide binding
FTS_RS04890	COG0012	GTP binding
FTS_RS04910	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FTS_RS04925	COG3104	oligopeptide transport
FTS_RS04935	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FTS_RS04945	COG0095	Lipoate-protein ligase
FTS_RS04950	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FTS_RS04960	COG3335	DDE superfamily endonuclease
FTS_RS04975	COG3961	Belongs to the TPP enzyme family
FTS_RS04980	COG0277	FAD linked oxidase domain protein
FTS_RS04990	COG1979	alcohol dehydrogenase
FTS_RS04995	COG2264	protein methyltransferase activity
FTS_RS05000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FTS_RS05005	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FTS_RS05010	COG2852	Protein conserved in bacteria
FTS_RS05035	COG0488	(ABC) transporter
FTS_RS05045	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FTS_RS05075	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FTS_RS05085	COG3335	DDE superfamily endonuclease
FTS_RS05090	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FTS_RS05105	COG0450	alkyl hydroperoxide reductase
FTS_RS05145	COG1876	peptidase activity
FTS_RS05160	COG1012	belongs to the aldehyde dehydrogenase family
FTS_RS05170	COG1937	Protein conserved in bacteria
FTS_RS05175	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FTS_RS05180	COG0583	DNA-binding transcription factor activity
FTS_RS05200	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FTS_RS05215	COG3335	DDE superfamily endonuclease
FTS_RS05265	COG1187	pseudouridine synthase activity
FTS_RS05325	COG0142	geranyltranstransferase activity
FTS_RS05350	COG2027	D-alanyl-D-alanine carboxypeptidase
FTS_RS05360	COG1610	YqeY-like protein
FTS_RS05365	COG0358	DNA primase activity
FTS_RS05375	COG1252	NADH dehydrogenase
FTS_RS05380	COG1501	Belongs to the glycosyl hydrolase 31 family
FTS_RS05385	COG1501	Belongs to the glycosyl hydrolase 31 family
FTS_RS05390	COG1501	Belongs to the glycosyl hydrolase 31 family
FTS_RS05395	COG1501	Belongs to the glycosyl hydrolase 31 family
FTS_RS05410	COG2921	Belongs to the UPF0250 family
FTS_RS05415	COG1686	Belongs to the peptidase S11 family
FTS_RS05420	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FTS_RS05425	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FTS_RS05440	COG1137	ATPase activity
FTS_RS05445	COG0179	Fumarylacetoacetate (FAA) hydrolase
FTS_RS05450	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FTS_RS05490	COG1028	Short-chain dehydrogenase reductase Sdr
FTS_RS05510	COG3655	Transcriptional regulator
FTS_RS05555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FTS_RS05565	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FTS_RS05570	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FTS_RS05635	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FTS_RS05640	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FTS_RS05670	COG0354	folic acid binding
FTS_RS05675	COG0210	DNA helicase
FTS_RS05680	COG2996	Protein conserved in bacteria
FTS_RS05690	COG2974	May be involved in recombination
FTS_RS05735	COG3550	peptidyl-serine autophosphorylation
FTS_RS05740	COG1396	sequence-specific DNA binding
FTS_RS05750	COG3335	DDE superfamily endonuclease
FTS_RS05775	COG0483	inositol monophosphate 1-phosphatase activity
FTS_RS05780	COG2855	membrane
FTS_RS05790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FTS_RS05790	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FTS_RS05800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FTS_RS05805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FTS_RS05810	COG1028	Short-chain dehydrogenase reductase Sdr
FTS_RS05815	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FTS_RS05855	COG0469	pyruvate kinase activity
FTS_RS05860	COG0191	fructose-bisphosphate aldolase activity
FTS_RS05865	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FTS_RS05880	COG3335	DDE superfamily endonuclease
FTS_RS05885	COG0738	Major facilitator superfamily
FTS_RS06005	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FTS_RS06020	COG0583	DNA-binding transcription factor activity
FTS_RS06080	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FTS_RS06095	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FTS_RS06115	COG0583	DNA-binding transcription factor activity
FTS_RS06130	COG3335	DDE superfamily endonuclease
FTS_RS06135	COG0697	spore germination
FTS_RS06145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FTS_RS06145	COG0072	phenylalanine-tRNA ligase activity
FTS_RS06150	COG0735	belongs to the Fur family
FTS_RS06155	COG0523	cobalamin synthesis protein
FTS_RS06170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FTS_RS06175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FTS_RS06185	COG0489	protein tyrosine kinase activity
FTS_RS06250	COG0833	amino acid
FTS_RS06285	COG0719	Fe-S assembly protein
FTS_RS06290	COG0396	ATPase activity
FTS_RS06295	COG0719	Fe-S assembly protein
FTS_RS06305	COG0569	domain protein
FTS_RS06310	COG0531	amino acid
FTS_RS06340	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FTS_RS06345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FTS_RS06350	COG3335	DDE superfamily endonuclease
FTS_RS06370	COG0708	Exodeoxyribonuclease III
FTS_RS06375	COG1028	Short-chain dehydrogenase reductase Sdr
FTS_RS06390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FTS_RS06405	COG3104	oligopeptide transport
FTS_RS06410	COG0513	Belongs to the DEAD box helicase family
FTS_RS06415	COG0302	gtp cyclohydrolase
FTS_RS06440	COG0667	Aldo Keto reductase
FTS_RS06445	COG2271	Major facilitator Superfamily
FTS_RS06455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FTS_RS06455	COG0512	Glutamine amidotransferase of anthranilate synthase
FTS_RS06460	COG0512	Glutamine amidotransferase of anthranilate synthase
FTS_RS06460	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FTS_RS06470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FTS_RS06475	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FTS_RS06475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FTS_RS06495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FTS_RS06505	COG0156	8-amino-7-oxononanoate synthase activity
FTS_RS06520	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FTS_RS06520	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FTS_RS06540	COG1028	Short-chain dehydrogenase reductase Sdr
FTS_RS06545	COG1028	Short-chain dehydrogenase reductase Sdr
FTS_RS06550	COG1472	Belongs to the glycosyl hydrolase 3 family
FTS_RS06560	COG0189	ligase activity
FTS_RS06595	COG3335	DDE superfamily endonuclease
FTS_RS06605	COG2081	HI0933 family
FTS_RS06615	COG0300	oxidoreductase activity
FTS_RS06635	COG3335	DDE superfamily endonuclease
FTS_RS06665	COG2918	glutathione biosynthetic process
FTS_RS06670	COG0728	peptidoglycan biosynthetic process
FTS_RS06680	COG0802	atpase or kinase
FTS_RS06685	COG0285	dihydrofolate synthase activity
FTS_RS06690	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FTS_RS06705	COG1288	antiporter activity
FTS_RS06710	COG1288	antiporter activity
FTS_RS06730	COG3335	DDE superfamily endonuclease
FTS_RS06785	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FTS_RS06795	COG2151	metal-sulfur cluster biosynthetic enzyme
FTS_RS06800	COG0316	Belongs to the HesB IscA family
FTS_RS06805	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FTS_RS06810	COG1760	l-serine dehydratase
FTS_RS06820	COG0077	Prephenate dehydratase
FTS_RS06820	COG1605	Chorismate mutase
FTS_RS06835	COG3104	oligopeptide transport
FTS_RS06880	COG0751	glycine-tRNA ligase activity
FTS_RS06885	COG0084	hydrolase, TatD family'
FTS_RS06910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FTS_RS06915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FTS_RS06920	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FTS_RS06925	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FTS_RS06955	COG1278	Cold shock
FTS_RS06960	COG1509	lysine 2,3-aminomutase activity
FTS_RS06995	COG3335	DDE superfamily endonuclease
FTS_RS07035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FTS_RS07040	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FTS_RS07040	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FTS_RS07070	COG0386	Belongs to the glutathione peroxidase family
FTS_RS07110	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FTS_RS07120	COG0513	Belongs to the DEAD box helicase family
FTS_RS07125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FTS_RS07130	COG2814	Major facilitator Superfamily
FTS_RS07135	COG2814	Major facilitator Superfamily
FTS_RS07140	COG1085	galactose-1-phosphate uridylyltransferase
FTS_RS07170	COG3335	DDE superfamily endonuclease
FTS_RS07210	COG3397	chitin binding
FTS_RS07220	COG0509	glycine decarboxylation via glycine cleavage system
FTS_RS07240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FTS_RS07260	COG0477	Major facilitator Superfamily
FTS_RS07290	COG1446	asparaginase
FTS_RS07310	COG0438	transferase activity, transferring glycosyl groups
FTS_RS07315	COG1442	glycosyl transferase family 8
FTS_RS07315	COG1216	Glycosyl transferase, family 2
FTS_RS07320	COG1442	glycosyl transferase family 8
FTS_RS07320	COG1216	Glycosyl transferase, family 2
FTS_RS07325	COG3475	LICD family
FTS_RS07340	COG1132	(ABC) transporter
FTS_RS07350	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FTS_RS07355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FTS_RS07360	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FTS_RS07365	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FTS_RS07365	COG0517	IMP dehydrogenase activity
FTS_RS07380	COG3220	belongs to the UPF0276 family
FTS_RS07405	COG1611	Belongs to the LOG family
FTS_RS07435	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FTS_RS07440	COG2814	Major facilitator Superfamily
FTS_RS07485	COG0813	purine-nucleoside phosphorylase activity
FTS_RS07490	COG3335	DDE superfamily endonuclease
FTS_RS07505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FTS_RS07525	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FTS_RS07550	COG0517	IMP dehydrogenase activity
FTS_RS07550	COG0516	GMP reductase activity
FTS_RS07560	COG0795	lipopolysaccharide-transporting ATPase activity
FTS_RS07565	COG0795	lipopolysaccharide-transporting ATPase activity
FTS_RS07580	COG0742	ribosomal rna small subunit methyltransferase
FTS_RS07585	COG2860	membrane
FTS_RS07595	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FTS_RS07600	COG0295	cytidine deaminase activity
FTS_RS07610	COG0247	lactate metabolic process
FTS_RS07610	COG0277	FAD linked oxidase domain protein
FTS_RS07625	COG1940	carbohydrate kinase activity
FTS_RS07645	COG4988	ABC transporter
FTS_RS07650	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FTS_RS07660	COG0251	oxidation-reduction process
FTS_RS07665	COG0659	secondary active sulfate transmembrane transporter activity
FTS_RS07680	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FTS_RS07690	COG3335	DDE superfamily endonuclease
FTS_RS07710	COG2271	Major facilitator Superfamily
FTS_RS07715	COG0584	glycerophosphoryl diester phosphodiesterase
FTS_RS07725	COG1131	(ABC) transporter
FTS_RS07760	COG0156	8-amino-7-oxononanoate synthase activity
FTS_RS07770	COG0814	amino acid
FTS_RS07775	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FTS_RS07780	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FTS_RS07800	COG1940	carbohydrate kinase activity
FTS_RS07855	COG3116	cell division
FTS_RS07865	COG0318	PFAM AMP-dependent synthetase and ligase
FTS_RS07865	COG0204	Acyl-transferase
FTS_RS07870	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FTS_RS07880	COG3335	DDE superfamily endonuclease
FTS_RS07905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FTS_RS07935	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FTS_RS07945	COG0628	permease
FTS_RS07980	COG2814	Major facilitator Superfamily
FTS_RS07985	COG0583	DNA-binding transcription factor activity
FTS_RS07990	COG0546	phosphoglycolate phosphatase activity
FTS_RS07995	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FTS_RS08000	COG0492	ferredoxin-NADP+ reductase activity
FTS_RS08020	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FTS_RS08035	COG1162	GTPase activity
FTS_RS08050	COG0531	amino acid
FTS_RS08060	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FTS_RS08065	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FTS_RS08065	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FTS_RS08095	COG0439	Biotin carboxylase
FTS_RS08110	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FTS_RS08120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FTS_RS08140	COG0252	asparaginase activity
FTS_RS08145	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FTS_RS08150	COG0113	porphobilinogen synthase activity
FTS_RS08160	COG0470	DNA polymerase III
FTS_RS08165	COG0616	signal peptide processing
FTS_RS08170	COG0625	glutathione transferase activity
FTS_RS08175	COG2920	part of a sulfur-relay system
FTS_RS08185	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FTS_RS08190	COG3335	DDE superfamily endonuclease
FTS_RS08200	COG0463	Glycosyl transferase, family 2
FTS_RS08210	COG0772	Belongs to the SEDS family
FTS_RS08225	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FTS_RS08230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FTS_RS08245	COG0488	(ABC) transporter
FTS_RS08260	COG2814	Major facilitator Superfamily
FTS_RS08280	COG3335	DDE superfamily endonuclease
FTS_RS08290	COG3335	DDE superfamily endonuclease
FTS_RS08315	COG0583	DNA-binding transcription factor activity
FTS_RS08335	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FTS_RS08350	COG0531	amino acid
FTS_RS08370	COG3335	DDE superfamily endonuclease
FTS_RS08390	COG2814	Major facilitator Superfamily
FTS_RS08395	COG0444	Belongs to the ABC transporter superfamily
FTS_RS08410	COG4166	transmembrane transport
FTS_RS08425	COG0210	DNA helicase
FTS_RS08430	COG0552	protein localization to endoplasmic reticulum
FTS_RS08450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FTS_RS08455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FTS_RS08460	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FTS_RS08465	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FTS_RS08475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FTS_RS08475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FTS_RS08500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FTS_RS08505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FTS_RS08525	COG1619	proteins homologs of microcin C7 resistance protein MccF
FTS_RS08540	COG3335	DDE superfamily endonuclease
FTS_RS08555	COG2890	protein-(glutamine-N5) methyltransferase activity
FTS_RS08560	COG2814	Major facilitator Superfamily
FTS_RS08565	COG0456	acetyltransferase
FTS_RS08575	COG3335	DDE superfamily endonuclease
FTS_RS08630	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FTS_RS08635	COG1494	fructose-1,6-bisphosphatase
FTS_RS08640	COG2945	thiolester hydrolase activity
FTS_RS08645	COG0833	amino acid
FTS_RS08655	COG1674	ftsk spoiiie
FTS_RS08670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FTS_RS08695	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FTS_RS08705	COG3335	DDE superfamily endonuclease
FTS_RS08735	COG3335	DDE superfamily endonuclease
FTS_RS08750	COG2890	protein-(glutamine-N5) methyltransferase activity
FTS_RS08770	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FTS_RS08775	COG2814	Major facilitator Superfamily
FTS_RS08785	COG3023	N-Acetylmuramoyl-L-alanine amidase
FTS_RS08830	COG4974	Belongs to the 'phage' integrase family
FTS_RS08910	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FTS_RS08940	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FTS_RS08955	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FTS_RS08970	COG3335	DDE superfamily endonuclease
FTS_RS08995	COG1090	epimerase
FTS_RS09005	COG1271	oxidase subunit
FTS_RS09010	COG1294	oxidase, subunit
FTS_RS09020	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
FTS_RS09055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FTS_RS09080	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FTS_RS09115	COG1053	succinate dehydrogenase
FTS_RS09120	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FTS_RS09135	COG2223	nitrite transmembrane transporter activity
FTS_RS09150	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FTS_RS09210	COG0564	pseudouridine synthase activity
FTS_RS09215	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FTS_RS09240	COG2251	uridine kinase activity
FTS_RS09240	COG0195	Participates in both transcription termination and antitermination
FTS_RS09265	COG3335	DDE superfamily endonuclease
FTS_RS09300	COG0839	Belongs to the complex I subunit 6 family
FTS_RS09315	COG1034	ATP synthesis coupled electron transport
FTS_RS09325	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FTS_RS09345	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FTS_RS09355	COG4264	IucA IucC family
FTS_RS09360	COG2814	Major facilitator Superfamily
FTS_RS09365	COG0019	diaminopimelate decarboxylase activity
FTS_RS09370	COG2814	Major facilitator Superfamily
FTS_RS09405	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FTS_RS09425	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FTS_RS09475	COG0047	phosphoribosylformylglycinamidine synthase activity
FTS_RS09475	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FTS_RS09480	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FTS_RS09495	COG1538	Outer membrane efflux protein
FTS_RS09505	COG0826	peptidase U32
FTS_RS09515	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FTS_RS09525	COG0531	amino acid
FTS_RS09535	COG0814	amino acid
FTS_RS09565	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FTS_RS09585	COG3335	DDE superfamily endonuclease
FTS_RS09605	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FTS_RS09615	COG3335	DDE superfamily endonuclease
FTS_RS09635	COG3040	lipid binding
FTS_RS09650	COG2066	Belongs to the glutaminase family
FTS_RS09660	COG2862	Uncharacterized protein family, UPF0114
FTS_RS09665	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FTS_RS09675	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FTS_RS09695	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FTS_RS09715	COG0009	L-threonylcarbamoyladenylate synthase
FTS_RS09725	COG0204	Acyl-transferase
FTS_RS09730	COG0658	competence protein
FTS_RS09730	COG2333	competence protein COMEC
FTS_RS09740	COG1181	Belongs to the D-alanine--D-alanine ligase family
FTS_RS09755	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FTS_RS09775	COG3335	DDE superfamily endonuclease
FTS_RS09785	COG3293	Transposase
FTS_RS09795	COG0138	bifunctional purine biosynthesis protein purh
FTS_RS09820	COG1121	(ABC) transporter
FTS_RS09845	COG1295	ribonuclease BN
FTS_RS09855	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FTS_RS09865	COG3335	DDE superfamily endonuclease
FTS_RS09875	COG0488	(ABC) transporter
FTS_RS09920	COG0308	aminopeptidase N
FTS_RS09925	COG0071	Belongs to the small heat shock protein (HSP20) family
FTS_RS09930	COG0135	phosphoribosylanthranilate isomerase activity
FTS_RS09930	COG0134	indole-3-glycerol-phosphate synthase activity
FTS_RS09940	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FTS_RS09965	COG0512	Glutamine amidotransferase of anthranilate synthase
FTS_RS09970	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia