locus-tag	class	description
FSYMDG_RS00010	COG1847	R3H domain protein
FSYMDG_RS00015	COG0706	membrane insertase activity
FSYMDG_RS00020	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FSYMDG_RS00025	COG0594	ribonuclease P activity
FSYMDG_RS00030	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FSYMDG_RS00035	COG0592	DNA-directed DNA polymerase activity
FSYMDG_RS00040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FSYMDG_RS00045	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FSYMDG_RS00050	COG0187	DNA topoisomerase II activity
FSYMDG_RS00055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FSYMDG_RS00100	COG0574	Belongs to the PEP-utilizing enzyme family
FSYMDG_RS00100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FSYMDG_RS00140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FSYMDG_RS00155	COG0586	Pfam SNARE associated Golgi protein
FSYMDG_RS00160	COG1881	PFAM PEBP family protein
FSYMDG_RS00175	COG1120	ATPase activity
FSYMDG_RS00180	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FSYMDG_RS00185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FSYMDG_RS00190	COG4607	ABC-type enterochelin transport system periplasmic component
FSYMDG_RS00205	COG3251	PFAM MbtH domain protein
FSYMDG_RS00210	COG1132	(ABC) transporter
FSYMDG_RS00225	COG1132	(ABC) transporter
FSYMDG_RS00240	COG4974	Belongs to the 'phage' integrase family
FSYMDG_RS00295	COG2801	Transposase and inactivated derivatives
FSYMDG_RS00300	COG2963	transposase activity
FSYMDG_RS00320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FSYMDG_RS00330	COG2963	transposase activity
FSYMDG_RS00335	COG2801	Transposase and inactivated derivatives
FSYMDG_RS00360	COG0242	peptide deformylase activity
FSYMDG_RS00405	COG4974	Belongs to the 'phage' integrase family
FSYMDG_RS00460	COG1674	ftsk spoiiie
FSYMDG_RS00475	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FSYMDG_RS00490	COG0791	NLP P60 protein
FSYMDG_RS00490	COG3883	PFAM NLP P60 protein
FSYMDG_RS00500	COG2963	transposase activity
FSYMDG_RS00505	COG2801	Transposase and inactivated derivatives
FSYMDG_RS00555	COG2801	Transposase and inactivated derivatives
FSYMDG_RS00560	COG2963	transposase activity
FSYMDG_RS00620	COG0494	nUDIX hydrolase
FSYMDG_RS00645	COG3328	transposase activity
FSYMDG_RS00650	COG2963	transposase activity
FSYMDG_RS00655	COG2801	Transposase and inactivated derivatives
FSYMDG_RS00675	COG1960	acyl-CoA dehydrogenase activity
FSYMDG_RS00680	COG2197	response regulator
FSYMDG_RS00685	COG3385	transposase activity
FSYMDG_RS00690	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
FSYMDG_RS00720	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
FSYMDG_RS00740	COG0644	oxidoreductase
FSYMDG_RS00760	COG0047	phosphoribosylformylglycinamidine synthase activity
FSYMDG_RS00775	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FSYMDG_RS00790	COG2814	Major facilitator Superfamily
FSYMDG_RS00800	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FSYMDG_RS00805	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FSYMDG_RS00810	COG1278	Cold shock
FSYMDG_RS00825	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FSYMDG_RS00830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FSYMDG_RS00845	COG0018	arginyl-trna synthetase
FSYMDG_RS00880	COG1716	ATPase activity
FSYMDG_RS00895	COG0768	penicillin binding
FSYMDG_RS00900	COG0515	serine threonine protein kinase
FSYMDG_RS00905	COG2815	serine threonine protein kinase
FSYMDG_RS00905	COG0515	serine threonine protein kinase
FSYMDG_RS00915	COG0318	PFAM AMP-dependent synthetase and ligase
FSYMDG_RS01025	COG2801	Transposase and inactivated derivatives
FSYMDG_RS01035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FSYMDG_RS01045	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FSYMDG_RS01060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSYMDG_RS01155	COG1691	(AIR) carboxylase
FSYMDG_RS01195	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FSYMDG_RS01240	COG1573	uracil-dna glycosylase
FSYMDG_RS01255	COG0259	pyridoxamine-phosphate oxidase activity
FSYMDG_RS01265	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FSYMDG_RS01270	COG0372	Belongs to the citrate synthase family
FSYMDG_RS01275	COG0667	Aldo Keto reductase
FSYMDG_RS01310	COG1116	anion transmembrane transporter activity
FSYMDG_RS01315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FSYMDG_RS01320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSYMDG_RS01325	COG0431	NADPH-dependent FMN reductase
FSYMDG_RS01335	COG1960	acyl-CoA dehydrogenase activity
FSYMDG_RS01365	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FSYMDG_RS01400	COG0579	oxidoreductase
FSYMDG_RS01425	COG1487	ribonuclease activity
FSYMDG_RS01450	COG2267	carboxylic ester hydrolase activity
FSYMDG_RS01460	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FSYMDG_RS01495	COG0745	RESPONSE REGULATOR receiver
FSYMDG_RS01500	COG5002	protein histidine kinase activity
FSYMDG_RS01505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FSYMDG_RS01515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS01540	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FSYMDG_RS01545	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FSYMDG_RS01550	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FSYMDG_RS01590	COG2272	Belongs to the type-B carboxylesterase lipase family
FSYMDG_RS01625	COG1131	(ABC) transporter
FSYMDG_RS01635	COG0582	viral genome integration into host DNA
FSYMDG_RS01675	COG2801	Transposase and inactivated derivatives
FSYMDG_RS01685	COG1595	DNA-templated transcription, initiation
FSYMDG_RS01720	COG3467	pyridoxamine 5'-phosphate
FSYMDG_RS01760	COG2076	Multidrug Resistance protein
FSYMDG_RS01770	COG1024	Enoyl-CoA hydratase
FSYMDG_RS01795	COG0318	PFAM AMP-dependent synthetase and ligase
FSYMDG_RS01845	COG1846	Transcriptional regulator
FSYMDG_RS01850	COG0477	Major facilitator Superfamily
FSYMDG_RS01860	COG2402	Toxic component of a toxin-antitoxin (TA) module. An RNase
FSYMDG_RS01865	COG3304	Inner membrane component domain
FSYMDG_RS01870	COG0596	Alpha beta hydrolase
FSYMDG_RS01875	COG2026	Addiction module toxin, RelE StbE family
FSYMDG_RS01890	COG0747	negative chemotaxis
FSYMDG_RS01900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FSYMDG_RS01905	COG4172	Belongs to the ABC transporter superfamily
FSYMDG_RS01915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS01920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS01925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS01945	COG2365	Tyrosine phosphatase family
FSYMDG_RS01955	COG2963	transposase activity
FSYMDG_RS01960	COG2801	Transposase and inactivated derivatives
FSYMDG_RS01965	COG0346	lactoylglutathione lyase activity
FSYMDG_RS01995	COG2186	Transcriptional regulator
FSYMDG_RS02015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSYMDG_RS02035	COG3321	synthase
FSYMDG_RS02035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FSYMDG_RS02045	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
FSYMDG_RS02080	COG3842	ATPase activity
FSYMDG_RS02120	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FSYMDG_RS02135	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FSYMDG_RS02140	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FSYMDG_RS02145	COG0235	Class ii aldolase
FSYMDG_RS02145	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FSYMDG_RS02155	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FSYMDG_RS02230	COG2801	Transposase and inactivated derivatives
FSYMDG_RS02295	COG0842	Transport permease protein
FSYMDG_RS02295	COG1131	(ABC) transporter
FSYMDG_RS02295	COG1716	ATPase activity
FSYMDG_RS02300	COG1192	Involved in chromosome partitioning
FSYMDG_RS02320	COG1028	Short-chain dehydrogenase reductase Sdr
FSYMDG_RS02330	COG3385	transposase activity
FSYMDG_RS02375	COG0297	glycogen (starch) synthase activity
FSYMDG_RS02380	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FSYMDG_RS02390	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FSYMDG_RS02435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FSYMDG_RS02450	COG2867	negative regulation of translational initiation
FSYMDG_RS02485	COG2018	Roadblock/LC7 domain
FSYMDG_RS02495	COG0515	serine threonine protein kinase
FSYMDG_RS02495	COG2815	serine threonine protein kinase
FSYMDG_RS02515	COG1131	(ABC) transporter
FSYMDG_RS02525	COG2301	Belongs to the HpcH HpaI aldolase family
FSYMDG_RS02535	COG0641	radical SAM
FSYMDG_RS02585	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FSYMDG_RS02615	COG2205	protein histidine kinase activity
FSYMDG_RS02615	COG4999	Histidine kinase
FSYMDG_RS02615	COG3437	response regulator, receiver
FSYMDG_RS02615	COG3850	Histidine kinase
FSYMDG_RS02620	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FSYMDG_RS02625	COG0640	Transcriptional regulator
FSYMDG_RS02640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FSYMDG_RS02645	COG2197	response regulator
FSYMDG_RS02660	COG2963	transposase activity
FSYMDG_RS02665	COG2801	Transposase and inactivated derivatives
FSYMDG_RS02680	COG3655	Transcriptional regulator
FSYMDG_RS02700	COG0346	lactoylglutathione lyase activity
FSYMDG_RS02710	COG2197	response regulator
FSYMDG_RS02735	COG1595	DNA-templated transcription, initiation
FSYMDG_RS02755	COG3385	transposase activity
FSYMDG_RS02760	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
FSYMDG_RS02770	COG3385	transposase activity
FSYMDG_RS02805	COG1271	oxidase subunit
FSYMDG_RS02810	COG1294	oxidase, subunit
FSYMDG_RS02835	COG0745	RESPONSE REGULATOR receiver
FSYMDG_RS02840	COG2205	protein histidine kinase activity
FSYMDG_RS02845	COG3119	arylsulfatase activity
FSYMDG_RS02850	COG0667	Aldo Keto reductase
FSYMDG_RS02865	COG1278	Cold shock
FSYMDG_RS02870	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FSYMDG_RS02900	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FSYMDG_RS02905	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FSYMDG_RS02980	COG1652	LysM domain
FSYMDG_RS03000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FSYMDG_RS03015	COG2409	Drug exporters of the RND superfamily
FSYMDG_RS03020	COG2313	pseudouridylate synthase activity
FSYMDG_RS03025	COG0542	response to heat
FSYMDG_RS03030	COG0789	Transcriptional regulator
FSYMDG_RS03035	COG0484	heat shock protein binding
FSYMDG_RS03040	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FSYMDG_RS03045	COG0443	Heat shock 70 kDa protein
FSYMDG_RS03055	COG2181	nitrate reductase activity
FSYMDG_RS03055	COG0247	lactate metabolic process
FSYMDG_RS03060	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FSYMDG_RS03060	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FSYMDG_RS03075	COG0717	Belongs to the dCTP deaminase family
FSYMDG_RS03090	COG1487	ribonuclease activity
FSYMDG_RS03100	COG1028	Short-chain dehydrogenase reductase Sdr
FSYMDG_RS03120	COG3483	tryptophan 2,3-dioxygenase activity
FSYMDG_RS03165	COG0598	Magnesium transport protein CorA
FSYMDG_RS03215	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FSYMDG_RS03290	COG0561	phosphatase activity
FSYMDG_RS03295	COG0140	phosphoribosyl-ATP diphosphatase activity
FSYMDG_RS03300	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FSYMDG_RS03305	COG0302	gtp cyclohydrolase
FSYMDG_RS03315	COG0037	tRNA processing
FSYMDG_RS03325	COG2027	D-alanyl-D-alanine carboxypeptidase
FSYMDG_RS03330	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FSYMDG_RS03345	COG0745	RESPONSE REGULATOR receiver
FSYMDG_RS03355	COG1774	PSP1 C-terminal conserved region
FSYMDG_RS03395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS03425	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FSYMDG_RS03425	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FSYMDG_RS03455	COG1215	transferase activity, transferring glycosyl groups
FSYMDG_RS03465	COG2409	Drug exporters of the RND superfamily
FSYMDG_RS03475	COG0174	glutamine synthetase
FSYMDG_RS03515	COG0019	diaminopimelate decarboxylase activity
FSYMDG_RS03530	COG5002	protein histidine kinase activity
FSYMDG_RS03530	COG2205	protein histidine kinase activity
FSYMDG_RS03530	COG0784	Response regulator, receiver
FSYMDG_RS03560	COG3387	PFAM Glycoside hydrolase 15-related
FSYMDG_RS03605	COG0084	hydrolase, TatD family'
FSYMDG_RS03610	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FSYMDG_RS03625	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FSYMDG_RS03630	COG0488	(ABC) transporter
FSYMDG_RS03645	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FSYMDG_RS03650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FSYMDG_RS03655	COG1742	UPF0060 membrane protein
FSYMDG_RS03660	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FSYMDG_RS03665	COG0193	aminoacyl-tRNA hydrolase activity
FSYMDG_RS03695	COG0616	signal peptide processing
FSYMDG_RS03700	COG0148	phosphopyruvate hydratase activity
FSYMDG_RS03735	COG2801	Transposase and inactivated derivatives
FSYMDG_RS03745	COG1252	NADH dehydrogenase
FSYMDG_RS03780	COG3447	MASE1 domain protein
FSYMDG_RS03780	COG5001	Diguanylate cyclase
FSYMDG_RS03780	COG5002	protein histidine kinase activity
FSYMDG_RS03795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FSYMDG_RS03805	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FSYMDG_RS03820	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FSYMDG_RS03830	COG0495	leucyl-tRNA aminoacylation
FSYMDG_RS03840	COG1331	Highly conserved protein containing a thioredoxin domain
FSYMDG_RS03855	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FSYMDG_RS03860	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FSYMDG_RS03865	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FSYMDG_RS03875	COG0778	Nitroreductase
FSYMDG_RS03930	COG0114	fumarate hydratase activity
FSYMDG_RS03955	COG1722	exodeoxyribonuclease VII activity
FSYMDG_RS03960	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FSYMDG_RS03970	COG2337	Toxic component of a toxin-antitoxin (TA) module
FSYMDG_RS04000	COG1570	exodeoxyribonuclease VII activity
FSYMDG_RS04005	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FSYMDG_RS04020	COG0438	transferase activity, transferring glycosyl groups
FSYMDG_RS04035	COG0438	transferase activity, transferring glycosyl groups
FSYMDG_RS04055	COG1322	Protein conserved in bacteria
FSYMDG_RS04060	COG0012	GTP binding
FSYMDG_RS04075	COG0494	nUDIX hydrolase
FSYMDG_RS04080	COG1217	gtp-binding protein TYPA
FSYMDG_RS04105	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FSYMDG_RS04125	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FSYMDG_RS04140	COG2171	N-acyltransferase activity
FSYMDG_RS04145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FSYMDG_RS04155	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FSYMDG_RS04165	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FSYMDG_RS04180	COG1595	DNA-templated transcription, initiation
FSYMDG_RS04190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FSYMDG_RS04195	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FSYMDG_RS04205	COG1846	Transcriptional regulator
FSYMDG_RS04210	COG0613	PHP domain protein
FSYMDG_RS04215	COG3540	Alkaline phosphatase
FSYMDG_RS04220	COG1597	lipid kinase activity
FSYMDG_RS04235	COG1012	belongs to the aldehyde dehydrogenase family
FSYMDG_RS04245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FSYMDG_RS04250	COG1993	acr, cog1993
FSYMDG_RS04255	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FSYMDG_RS04315	COG1960	acyl-CoA dehydrogenase activity
FSYMDG_RS04325	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
FSYMDG_RS04335	COG2239	Acts as a magnesium transporter
FSYMDG_RS04375	COG1253	flavin adenine dinucleotide binding
FSYMDG_RS04385	COG1192	Involved in chromosome partitioning
FSYMDG_RS04395	COG0513	Belongs to the DEAD box helicase family
FSYMDG_RS04420	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FSYMDG_RS04465	COG0180	Tryptophanyl-tRNA synthetase
FSYMDG_RS04480	COG0612	Peptidase, M16
FSYMDG_RS04530	COG2124	cytochrome p450
FSYMDG_RS04535	COG2124	cytochrome p450
FSYMDG_RS04545	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FSYMDG_RS04585	COG1615	UPF0182 protein
FSYMDG_RS04685	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FSYMDG_RS04690	COG1012	belongs to the aldehyde dehydrogenase family
FSYMDG_RS04710	COG0483	inositol monophosphate 1-phosphatase activity
FSYMDG_RS04720	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FSYMDG_RS04735	COG1595	DNA-templated transcription, initiation
FSYMDG_RS04740	COG5662	AntiSigma factor
FSYMDG_RS04760	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FSYMDG_RS04770	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FSYMDG_RS04775	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FSYMDG_RS04780	COG0156	8-amino-7-oxononanoate synthase activity
FSYMDG_RS04795	COG1597	lipid kinase activity
FSYMDG_RS04810	COG2172	sigma factor antagonist activity
FSYMDG_RS04825	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FSYMDG_RS04840	COG0604	alcohol dehydrogenase
FSYMDG_RS04845	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSYMDG_RS04845	COG0567	Dehydrogenase, E1 component
FSYMDG_RS04860	COG3385	transposase activity
FSYMDG_RS04870	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FSYMDG_RS04885	COG2009	succinate dehydrogenase
FSYMDG_RS04895	COG0515	serine threonine protein kinase
FSYMDG_RS04895	COG2815	serine threonine protein kinase
FSYMDG_RS04915	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FSYMDG_RS04920	COG2818	Glycosylase
FSYMDG_RS04930	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FSYMDG_RS04935	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FSYMDG_RS04940	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSYMDG_RS04960	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSYMDG_RS04960	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSYMDG_RS04980	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FSYMDG_RS04985	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FSYMDG_RS04990	COG1473	amidohydrolase
FSYMDG_RS04990	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FSYMDG_RS04995	COG2409	Drug exporters of the RND superfamily
FSYMDG_RS05020	COG4770	biotin carboxylase activity
FSYMDG_RS05025	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FSYMDG_RS05060	COG1316	TRANSCRIPTIONal
FSYMDG_RS05065	COG1316	TRANSCRIPTIONal
FSYMDG_RS05085	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSYMDG_RS05100	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FSYMDG_RS05115	COG2963	transposase activity
FSYMDG_RS05120	COG2801	Transposase and inactivated derivatives
FSYMDG_RS05220	COG2226	methyltransferase
FSYMDG_RS05230	COG0438	transferase activity, transferring glycosyl groups
FSYMDG_RS05245	COG2902	Dehydrogenase
FSYMDG_RS05250	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FSYMDG_RS05260	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
FSYMDG_RS05260	COG0778	Nitroreductase
FSYMDG_RS05265	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FSYMDG_RS05280	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FSYMDG_RS05320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSYMDG_RS05325	COG2835	tetraacyldisaccharide 4'-kinase activity
FSYMDG_RS05335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSYMDG_RS05350	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FSYMDG_RS05370	COG0714	Associated with various cellular activities
FSYMDG_RS05395	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FSYMDG_RS05400	COG2197	response regulator
FSYMDG_RS05410	COG0653	protein targeting
FSYMDG_RS05460	COG1012	belongs to the aldehyde dehydrogenase family
FSYMDG_RS05505	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FSYMDG_RS05530	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FSYMDG_RS05555	COG1648	precorrin-2 dehydrogenase activity
FSYMDG_RS05555	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FSYMDG_RS05560	COG4129	membrane
FSYMDG_RS05570	COG2133	pyrroloquinoline quinone binding
FSYMDG_RS05580	COG2884	Cell division ATP-binding protein ftsE
FSYMDG_RS05590	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FSYMDG_RS05600	COG3226	Transcriptional regulator
FSYMDG_RS05605	COG0596	Alpha beta hydrolase
FSYMDG_RS05625	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FSYMDG_RS05635	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FSYMDG_RS05645	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FSYMDG_RS05675	COG2409	Drug exporters of the RND superfamily
FSYMDG_RS05690	COG0300	oxidoreductase activity
FSYMDG_RS05705	COG1233	COG1233 Phytoene dehydrogenase and related
FSYMDG_RS05715	COG1657	PFAM Prenyltransferase squalene oxidase
FSYMDG_RS05765	COG2801	Transposase and inactivated derivatives
FSYMDG_RS05770	COG2963	transposase activity
FSYMDG_RS05785	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FSYMDG_RS05815	COG0804	urea catabolic process
FSYMDG_RS05820	COG0832	Belongs to the urease beta subunit family
FSYMDG_RS05825	COG0831	urea catabolic process
FSYMDG_RS05830	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FSYMDG_RS05855	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FSYMDG_RS05865	COG4266	Belongs to the allantoicase family
FSYMDG_RS06035	COG5001	Diguanylate cyclase
FSYMDG_RS06045	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FSYMDG_RS06075	COG1234	tRNA 3'-trailer cleavage
FSYMDG_RS06080	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FSYMDG_RS06085	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FSYMDG_RS06120	COG2963	transposase activity
FSYMDG_RS06125	COG2801	Transposase and inactivated derivatives
FSYMDG_RS06150	COG2801	Transposase and inactivated derivatives
FSYMDG_RS06170	COG2963	transposase activity
FSYMDG_RS06175	COG2801	Transposase and inactivated derivatives
FSYMDG_RS06195	COG2188	Transcriptional regulator
FSYMDG_RS06235	COG0741	lytic transglycosylase activity
FSYMDG_RS06310	COG0500	methyltransferase
FSYMDG_RS06340	COG0753	catalase activity
FSYMDG_RS06350	COG0386	Belongs to the glutathione peroxidase family
FSYMDG_RS06450	COG0596	Alpha beta hydrolase
FSYMDG_RS06455	COG1819	glycosyl
FSYMDG_RS06460	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FSYMDG_RS06470	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FSYMDG_RS06485	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FSYMDG_RS06490	COG1960	acyl-CoA dehydrogenase activity
FSYMDG_RS06495	COG1960	acyl-CoA dehydrogenase activity
FSYMDG_RS06505	COG0277	FAD linked oxidase domain protein
FSYMDG_RS06525	COG1716	ATPase activity
FSYMDG_RS06525	COG0842	Transport permease protein
FSYMDG_RS06525	COG1131	(ABC) transporter
FSYMDG_RS06540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS06560	COG1271	oxidase subunit
FSYMDG_RS06565	COG1294	oxidase, subunit
FSYMDG_RS06570	COG4988	ABC transporter
FSYMDG_RS06610	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FSYMDG_RS06645	COG2801	Transposase and inactivated derivatives
FSYMDG_RS06660	COG2963	transposase activity
FSYMDG_RS06665	COG2801	Transposase and inactivated derivatives
FSYMDG_RS06730	COG0477	Major facilitator Superfamily
FSYMDG_RS06740	COG2801	Transposase and inactivated derivatives
FSYMDG_RS06750	COG2801	Transposase and inactivated derivatives
FSYMDG_RS06755	COG2963	transposase activity
FSYMDG_RS06815	COG1674	ftsk spoiiie
FSYMDG_RS06840	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FSYMDG_RS06920	COG2801	Transposase and inactivated derivatives
FSYMDG_RS06940	COG1028	Short-chain dehydrogenase reductase Sdr
FSYMDG_RS06950	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FSYMDG_RS06965	COG1929	Belongs to the glycerate kinase type-1 family
FSYMDG_RS06970	COG2755	lipolytic protein G-D-S-L family
FSYMDG_RS07005	COG2022	thiamine diphosphate biosynthetic process
FSYMDG_RS07015	COG2022	thiamine diphosphate biosynthetic process
FSYMDG_RS07015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FSYMDG_RS07025	COG0726	polysaccharide deacetylase
FSYMDG_RS07030	COG1012	belongs to the aldehyde dehydrogenase family
FSYMDG_RS07035	COG2197	response regulator
FSYMDG_RS07040	COG1253	flavin adenine dinucleotide binding
FSYMDG_RS07060	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FSYMDG_RS07075	COG1741	Belongs to the pirin family
FSYMDG_RS07085	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FSYMDG_RS07090	COG0156	8-amino-7-oxononanoate synthase activity
FSYMDG_RS07115	COG0514	ATP-dependent DNA helicase (RecQ)
FSYMDG_RS07125	COG2378	regulation of single-species biofilm formation
FSYMDG_RS07135	COG2815	serine threonine protein kinase
FSYMDG_RS07135	COG0515	serine threonine protein kinase
FSYMDG_RS07160	COG2963	transposase activity
FSYMDG_RS07165	COG2801	Transposase and inactivated derivatives
FSYMDG_RS07175	COG0246	Mannitol dehydrogenase
FSYMDG_RS07245	COG0366	Alpha amylase catalytic
FSYMDG_RS07260	COG0668	transmembrane transport
FSYMDG_RS07265	COG0745	RESPONSE REGULATOR receiver
FSYMDG_RS07270	COG2205	protein histidine kinase activity
FSYMDG_RS07325	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FSYMDG_RS07330	COG0698	ribose 5-phosphate isomerase
FSYMDG_RS07340	COG0463	Glycosyl transferase, family 2
FSYMDG_RS07375	COG1131	(ABC) transporter
FSYMDG_RS07420	COG0544	peptidyl-prolyl cis-trans isomerase activity
FSYMDG_RS07425	COG0740	serine-type endopeptidase activity
FSYMDG_RS07430	COG0740	serine-type endopeptidase activity
FSYMDG_RS07435	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FSYMDG_RS07440	COG0285	dihydrofolate synthase activity
FSYMDG_RS07445	COG0105	UTP biosynthetic process
FSYMDG_RS07450	COG1077	Cell shape determining protein MreB Mrl
FSYMDG_RS07465	COG0768	penicillin binding
FSYMDG_RS07470	COG0772	Belongs to the SEDS family
FSYMDG_RS07485	COG1530	ribonuclease E activity
FSYMDG_RS07495	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FSYMDG_RS07500	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FSYMDG_RS07505	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FSYMDG_RS07510	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FSYMDG_RS07520	COG0420	3'-5' exonuclease activity
FSYMDG_RS07525	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FSYMDG_RS07560	COG2084	Dehydrogenase
FSYMDG_RS07565	COG0542	response to heat
FSYMDG_RS07585	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FSYMDG_RS07590	COG0799	negative regulation of ribosome biogenesis
FSYMDG_RS07595	COG0406	alpha-ribazole phosphatase activity
FSYMDG_RS07610	COG2801	Transposase and inactivated derivatives
FSYMDG_RS07615	COG2963	transposase activity
FSYMDG_RS07645	COG1968	undecaprenyl-diphosphatase activity
FSYMDG_RS07650	COG0745	RESPONSE REGULATOR receiver
FSYMDG_RS07655	COG2205	protein histidine kinase activity
FSYMDG_RS07675	COG1028	Short-chain dehydrogenase reductase Sdr
FSYMDG_RS07680	COG0667	Aldo Keto reductase
FSYMDG_RS07685	COG0583	DNA-binding transcription factor activity
FSYMDG_RS07695	COG0596	Alpha beta hydrolase
FSYMDG_RS07695	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSYMDG_RS07700	COG1846	Transcriptional regulator
FSYMDG_RS07705	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSYMDG_RS07710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS07725	COG1129	ABC transporter
FSYMDG_RS07730	COG1172	Belongs to the binding-protein-dependent transport system permease family
FSYMDG_RS07790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FSYMDG_RS07795	COG1609	Transcriptional regulator
FSYMDG_RS07825	COG2135	peptidase activity
FSYMDG_RS07840	COG2353	YceI-like domain
FSYMDG_RS07850	COG1555	photosystem II stabilization
FSYMDG_RS07850	COG1596	polysaccharide export
FSYMDG_RS07870	COG0268	Binds directly to 16S ribosomal RNA
FSYMDG_RS07875	COG0481	GTPase activity
FSYMDG_RS07890	COG1420	regulation of RNA biosynthetic process
FSYMDG_RS07895	COG0484	heat shock protein binding
FSYMDG_RS07910	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FSYMDG_RS07925	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FSYMDG_RS07930	COG0346	lactoylglutathione lyase activity
FSYMDG_RS07950	COG1381	Involved in DNA repair and RecF pathway recombination
FSYMDG_RS07955	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FSYMDG_RS07965	COG0423	glycine-tRNA ligase activity
FSYMDG_RS07990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FSYMDG_RS07990	COG0574	Belongs to the PEP-utilizing enzyme family
FSYMDG_RS08010	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FSYMDG_RS08015	COG0358	DNA primase activity
FSYMDG_RS08020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FSYMDG_RS08025	COG3764	Sortase (surface protein transpeptidase)
FSYMDG_RS08055	COG2801	Transposase and inactivated derivatives
FSYMDG_RS08105	COG2801	Transposase and inactivated derivatives
FSYMDG_RS08120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FSYMDG_RS08140	COG0438	transferase activity, transferring glycosyl groups
FSYMDG_RS08150	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
FSYMDG_RS08180	COG2963	transposase activity
FSYMDG_RS08185	COG2801	Transposase and inactivated derivatives
FSYMDG_RS08195	COG0673	inositol 2-dehydrogenase activity
FSYMDG_RS08205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FSYMDG_RS08215	COG0297	glycogen (starch) synthase activity
FSYMDG_RS08235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FSYMDG_RS08260	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FSYMDG_RS08265	COG0126	phosphoglycerate kinase activity
FSYMDG_RS08270	COG0149	triose-phosphate isomerase activity
FSYMDG_RS08275	COG4166	transmembrane transport
FSYMDG_RS08280	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FSYMDG_RS08295	COG0363	glucosamine-6-phosphate deaminase activity
FSYMDG_RS08310	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FSYMDG_RS08315	COG0109	protoheme IX farnesyltransferase activity
FSYMDG_RS08320	COG1612	heme a metabolic process
FSYMDG_RS08350	COG0719	Fe-S assembly protein
FSYMDG_RS08360	COG0396	ATPase activity
FSYMDG_RS08365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FSYMDG_RS08370	COG0822	iron-sulfur transferase activity
FSYMDG_RS08390	COG2963	transposase activity
FSYMDG_RS08410	COG2801	Transposase and inactivated derivatives
FSYMDG_RS08430	COG0583	DNA-binding transcription factor activity
FSYMDG_RS08445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS08450	COG1960	acyl-CoA dehydrogenase activity
FSYMDG_RS08455	COG0747	negative chemotaxis
FSYMDG_RS08485	COG2963	transposase activity
FSYMDG_RS08490	COG2801	Transposase and inactivated derivatives
FSYMDG_RS08495	COG1305	Transglutaminase-like
FSYMDG_RS08510	COG0488	(ABC) transporter
FSYMDG_RS08535	COG1132	(ABC) transporter
FSYMDG_RS08575	COG0579	oxidoreductase
FSYMDG_RS08580	COG3387	PFAM Glycoside hydrolase 15-related
FSYMDG_RS08605	COG0475	glutathione-regulated potassium exporter activity
FSYMDG_RS08610	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FSYMDG_RS08630	COG1872	DUF167
FSYMDG_RS08640	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FSYMDG_RS08660	COG0438	transferase activity, transferring glycosyl groups
FSYMDG_RS08670	COG0277	FAD linked oxidase domain protein
FSYMDG_RS08675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSYMDG_RS08700	COG1376	ErfK ybiS ycfS ynhG family protein
FSYMDG_RS08715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FSYMDG_RS08735	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FSYMDG_RS08740	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FSYMDG_RS08765	COG1160	GTP binding
FSYMDG_RS08795	COG0525	valine-tRNA ligase activity
FSYMDG_RS08805	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FSYMDG_RS08820	COG0756	dUTP diphosphatase activity
FSYMDG_RS08835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FSYMDG_RS08840	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FSYMDG_RS08870	COG0183	Belongs to the thiolase family
FSYMDG_RS08895	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FSYMDG_RS08900	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FSYMDG_RS08905	COG3253	May function as heme-dependent peroxidase
FSYMDG_RS08945	COG5634	Uncharacterized conserved protein (DUF2278)
FSYMDG_RS08950	COG3385	transposase activity
FSYMDG_RS08955	COG5634	Uncharacterized conserved protein (DUF2278)
FSYMDG_RS08985	COG1218	3'(2'),5'-bisphosphate nucleotidase
FSYMDG_RS08990	COG0175	sulfate reduction
FSYMDG_RS09025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FSYMDG_RS09035	COG1116	anion transmembrane transporter activity
FSYMDG_RS09040	COG0667	Aldo Keto reductase
FSYMDG_RS09050	COG0019	diaminopimelate decarboxylase activity
FSYMDG_RS09070	COG1032	radical SAM domain protein
FSYMDG_RS09075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FSYMDG_RS09130	COG1120	ATPase activity
FSYMDG_RS09190	COG1012	belongs to the aldehyde dehydrogenase family
FSYMDG_RS09200	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FSYMDG_RS09235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FSYMDG_RS09240	COG0569	domain protein
FSYMDG_RS09265	COG0698	ribose 5-phosphate isomerase
FSYMDG_RS09285	COG1309	transcriptional regulator
FSYMDG_RS09330	COG1028	Short-chain dehydrogenase reductase Sdr
FSYMDG_RS09350	COG2838	Isocitrate dehydrogenase
FSYMDG_RS09360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FSYMDG_RS09370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS09375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS09380	COG0747	negative chemotaxis
FSYMDG_RS09395	COG0477	Major facilitator Superfamily
FSYMDG_RS09400	COG0657	acetylesterase activity
FSYMDG_RS09455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FSYMDG_RS09465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS09470	COG2124	cytochrome p450
FSYMDG_RS09490	COG2197	response regulator
FSYMDG_RS09530	COG0069	glutamate synthase activity
FSYMDG_RS09570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS09580	COG0444	Belongs to the ABC transporter superfamily
FSYMDG_RS09590	COG0601	transmembrane transport
FSYMDG_RS09605	COG2963	transposase activity
FSYMDG_RS09630	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FSYMDG_RS09655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FSYMDG_RS09660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FSYMDG_RS09675	COG2963	transposase activity
FSYMDG_RS09680	COG2801	Transposase and inactivated derivatives
FSYMDG_RS09715	COG2801	Transposase and inactivated derivatives
FSYMDG_RS09720	COG2963	transposase activity
FSYMDG_RS09725	COG2801	Transposase and inactivated derivatives
FSYMDG_RS09735	COG3467	pyridoxamine 5'-phosphate
FSYMDG_RS09740	COG0740	serine-type endopeptidase activity
FSYMDG_RS09750	COG2172	sigma factor antagonist activity
FSYMDG_RS09750	COG1366	Belongs to the anti-sigma-factor antagonist family
FSYMDG_RS09750	COG2208	phosphoserine phosphatase activity
FSYMDG_RS09775	COG0492	ferredoxin-NADP+ reductase activity
FSYMDG_RS09780	COG2197	response regulator
FSYMDG_RS09785	COG0318	PFAM AMP-dependent synthetase and ligase
FSYMDG_RS09795	COG2197	response regulator
FSYMDG_RS09810	COG0318	PFAM AMP-dependent synthetase and ligase
FSYMDG_RS09820	COG2030	dehydratase
FSYMDG_RS09825	COG1960	acyl-CoA dehydrogenase activity
FSYMDG_RS09830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FSYMDG_RS09835	COG2186	Transcriptional regulator
FSYMDG_RS09840	COG1960	acyl-CoA dehydrogenase activity
FSYMDG_RS09850	COG1028	Short-chain dehydrogenase reductase Sdr
FSYMDG_RS09855	COG0183	Belongs to the thiolase family
FSYMDG_RS09860	COG0427	acetyl-CoA hydrolase
FSYMDG_RS09865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FSYMDG_RS09875	COG1024	Enoyl-CoA hydratase
FSYMDG_RS09900	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FSYMDG_RS09915	COG0633	Ferredoxin
FSYMDG_RS09950	COG2267	carboxylic ester hydrolase activity
FSYMDG_RS09965	COG1028	Short-chain dehydrogenase reductase Sdr
FSYMDG_RS09970	COG3971	2-oxopent-4-enoate hydratase activity
FSYMDG_RS09975	COG4569	acetaldehyde dehydrogenase (acetylating) activity
FSYMDG_RS09985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FSYMDG_RS09990	COG2197	response regulator
FSYMDG_RS09995	COG1960	acyl-CoA dehydrogenase activity
FSYMDG_RS10015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FSYMDG_RS10025	COG1024	Enoyl-CoA hydratase
FSYMDG_RS10060	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FSYMDG_RS10105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSYMDG_RS10120	COG1309	transcriptional regulator
FSYMDG_RS10150	COG0318	PFAM AMP-dependent synthetase and ligase
FSYMDG_RS10155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSYMDG_RS10160	COG1012	belongs to the aldehyde dehydrogenase family
FSYMDG_RS10165	COG0183	Belongs to the thiolase family
FSYMDG_RS10185	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FSYMDG_RS10215	COG1309	transcriptional regulator
FSYMDG_RS10235	COG2801	Transposase and inactivated derivatives
FSYMDG_RS10255	COG0726	polysaccharide deacetylase
FSYMDG_RS10260	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FSYMDG_RS10270	COG2826	transposase and inactivated derivatives, IS30 family
FSYMDG_RS10300	COG2801	Transposase and inactivated derivatives
FSYMDG_RS10315	COG2963	transposase activity
FSYMDG_RS10320	COG2801	Transposase and inactivated derivatives
FSYMDG_RS10325	COG2814	Major facilitator Superfamily
FSYMDG_RS10355	COG2409	Drug exporters of the RND superfamily
FSYMDG_RS10360	COG1309	transcriptional regulator
FSYMDG_RS10365	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FSYMDG_RS10370	COG1024	Enoyl-CoA hydratase
FSYMDG_RS10385	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FSYMDG_RS10395	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FSYMDG_RS10440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS10465	COG2050	protein possibly involved in aromatic compounds catabolism
FSYMDG_RS10475	COG5001	Diguanylate cyclase
FSYMDG_RS10475	COG3300	MHYT domain
FSYMDG_RS10495	COG2226	methyltransferase
FSYMDG_RS10500	COG0539	negative regulation of cytoplasmic translation
FSYMDG_RS10515	COG0237	dephospho-CoA kinase activity
FSYMDG_RS10520	COG0556	nucleotide-excision repair
FSYMDG_RS10545	COG4106	trans-aconitate 2-methyltransferase activity
FSYMDG_RS10555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FSYMDG_RS10570	COG0137	argininosuccinate synthase activity
FSYMDG_RS10595	COG0704	Plays a role in the regulation of phosphate uptake
FSYMDG_RS10610	COG0181	hydroxymethylbilane synthase activity
FSYMDG_RS10615	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FSYMDG_RS10615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FSYMDG_RS10620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FSYMDG_RS10625	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FSYMDG_RS10635	COG0322	excinuclease ABC activity
FSYMDG_RS10640	COG1660	Displays ATPase and GTPase activities
FSYMDG_RS10645	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FSYMDG_RS10650	COG1481	regulation of sporulation
FSYMDG_RS10655	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FSYMDG_RS10675	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FSYMDG_RS10680	COG0509	glycine decarboxylation via glycine cleavage system
FSYMDG_RS10720	COG1674	ftsk spoiiie
FSYMDG_RS10810	COG2963	transposase activity
FSYMDG_RS10815	COG2801	Transposase and inactivated derivatives
FSYMDG_RS10845	COG2124	cytochrome p450
FSYMDG_RS10860	COG0805	protein transport
FSYMDG_RS10865	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FSYMDG_RS10870	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FSYMDG_RS10880	COG3408	Glycogen debranching enzyme
FSYMDG_RS10880	COG3119	arylsulfatase activity
FSYMDG_RS10885	COG3119	arylsulfatase activity
FSYMDG_RS10885	COG3408	Glycogen debranching enzyme
FSYMDG_RS10905	COG0545	Peptidyl-prolyl cis-trans isomerase
FSYMDG_RS10910	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FSYMDG_RS10920	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FSYMDG_RS10925	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
FSYMDG_RS10945	COG4122	O-methyltransferase activity
FSYMDG_RS10950	COG1222	aaa ATPase
FSYMDG_RS10965	COG1994	Peptidase M50
FSYMDG_RS10965	COG0517	IMP dehydrogenase activity
FSYMDG_RS10975	COG0577	efflux transmembrane transporter activity
FSYMDG_RS10975	COG1136	(ABC) transporter
FSYMDG_RS10980	COG0577	efflux transmembrane transporter activity
FSYMDG_RS11000	COG2963	transposase activity
FSYMDG_RS11005	COG2801	Transposase and inactivated derivatives
FSYMDG_RS11080	COG0494	nUDIX hydrolase
FSYMDG_RS11150	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSYMDG_RS11155	COG1968	undecaprenyl-diphosphatase activity
FSYMDG_RS11170	COG0215	cysteine-tRNA ligase activity
FSYMDG_RS11185	COG0646	methionine synthase
FSYMDG_RS11185	COG1410	methionine synthase
FSYMDG_RS11215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FSYMDG_RS11220	COG2814	Major facilitator Superfamily
FSYMDG_RS11235	COG1733	regulation of RNA biosynthetic process
FSYMDG_RS11240	COG3261	NADH dehydrogenase
FSYMDG_RS11240	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FSYMDG_RS11245	COG0651	ATP synthesis coupled electron transport
FSYMDG_RS11255	COG0650	Formate hydrogenlyase subunit 4
FSYMDG_RS11265	COG3260	NADH ubiquinone oxidoreductase 20
FSYMDG_RS11280	COG2963	transposase activity
FSYMDG_RS11325	COG2963	transposase activity
FSYMDG_RS11330	COG2801	Transposase and inactivated derivatives
FSYMDG_RS11335	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FSYMDG_RS11340	COG1492	cobalamin metabolic process
FSYMDG_RS11370	COG2197	response regulator
FSYMDG_RS11415	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FSYMDG_RS11420	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FSYMDG_RS11430	COG1088	dTDP-glucose 4,6-dehydratase activity
FSYMDG_RS11435	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FSYMDG_RS11465	COG0477	Major facilitator Superfamily
FSYMDG_RS11475	COG2197	response regulator
FSYMDG_RS11490	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FSYMDG_RS11490	COG0825	malonyl-CoA metabolic process
FSYMDG_RS11495	COG0511	ligase activity, forming carbon-carbon bonds
FSYMDG_RS11520	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FSYMDG_RS11540	COG1797	cobyrinic acid a,c-diamide synthase activity
FSYMDG_RS11570	COG3385	transposase activity
FSYMDG_RS11590	COG2801	Transposase and inactivated derivatives
FSYMDG_RS11625	COG1063	alcohol dehydrogenase
FSYMDG_RS11630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FSYMDG_RS11635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FSYMDG_RS11640	COG1522	sequence-specific DNA binding
FSYMDG_RS11645	COG1228	amidohydrolase
FSYMDG_RS11675	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FSYMDG_RS11680	COG0318	PFAM AMP-dependent synthetase and ligase
FSYMDG_RS11685	COG3404	Formiminotransferase-cyclodeaminase
FSYMDG_RS11690	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FSYMDG_RS11700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FSYMDG_RS11705	COG2261	transglycosylase associated protein
FSYMDG_RS11735	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FSYMDG_RS11740	COG3629	intracellular signal transduction
FSYMDG_RS11765	COG1132	(ABC) transporter
FSYMDG_RS11780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FSYMDG_RS11795	COG0789	Transcriptional regulator
FSYMDG_RS11835	COG0477	Major facilitator Superfamily
FSYMDG_RS11850	COG1131	(ABC) transporter
FSYMDG_RS11855	COG2197	response regulator
FSYMDG_RS11860	COG4585	Histidine kinase
FSYMDG_RS11870	COG1937	Protein conserved in bacteria
FSYMDG_RS11965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FSYMDG_RS11980	COG1278	Cold shock
FSYMDG_RS12025	COG2963	transposase activity
FSYMDG_RS12050	COG2963	transposase activity
FSYMDG_RS12055	COG2801	Transposase and inactivated derivatives
FSYMDG_RS12085	COG3629	intracellular signal transduction
FSYMDG_RS12105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS12125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FSYMDG_RS12135	COG0747	negative chemotaxis
FSYMDG_RS12140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSYMDG_RS12155	COG0409	Hydrogenase expression formation protein
FSYMDG_RS12170	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FSYMDG_RS12180	COG0298	carbon dioxide binding
FSYMDG_RS12185	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FSYMDG_RS12195	COG0375	protein maturation
FSYMDG_RS12220	COG0657	acetylesterase activity
FSYMDG_RS12230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FSYMDG_RS12235	COG0740	serine-type endopeptidase activity
FSYMDG_RS12260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FSYMDG_RS12305	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FSYMDG_RS12310	COG0131	Imidazoleglycerol-phosphate dehydratase
FSYMDG_RS12315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FSYMDG_RS12320	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FSYMDG_RS12345	COG2161	toxin-antitoxin pair type II binding
FSYMDG_RS12350	COG4115	mRNA cleavage
FSYMDG_RS12430	COG0432	Pfam Uncharacterised protein family UPF0047
FSYMDG_RS12435	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FSYMDG_RS12460	COG1832	CoA-binding protein
FSYMDG_RS12475	COG1024	Enoyl-CoA hydratase
FSYMDG_RS12475	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FSYMDG_RS12520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FSYMDG_RS12525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FSYMDG_RS12535	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FSYMDG_RS12540	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FSYMDG_RS12545	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FSYMDG_RS12555	COG2255	four-way junction helicase activity
FSYMDG_RS12560	COG0632	four-way junction helicase activity
FSYMDG_RS12565	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FSYMDG_RS12575	COG0217	transcriptional regulatory protein
FSYMDG_RS12580	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FSYMDG_RS12585	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FSYMDG_RS12600	COG1560	Kdo2-lipid A biosynthetic process
FSYMDG_RS12605	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FSYMDG_RS12635	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FSYMDG_RS12660	COG0860	N-Acetylmuramoyl-L-alanine amidase
FSYMDG_RS12705	COG4608	Belongs to the ABC transporter superfamily
FSYMDG_RS12720	COG2963	transposase activity
FSYMDG_RS12725	COG2801	Transposase and inactivated derivatives
FSYMDG_RS12745	COG0477	Major facilitator Superfamily
FSYMDG_RS12755	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FSYMDG_RS12765	COG0560	Phosphoserine phosphatase
FSYMDG_RS12790	COG2267	carboxylic ester hydrolase activity
FSYMDG_RS12805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FSYMDG_RS12820	COG3424	synthase
FSYMDG_RS12865	COG2070	2-Nitropropane dioxygenase
FSYMDG_RS12885	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FSYMDG_RS12895	COG1940	carbohydrate kinase activity
FSYMDG_RS12910	COG1028	Short-chain dehydrogenase reductase Sdr
FSYMDG_RS12915	COG1834	amidinotransferase
FSYMDG_RS12945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FSYMDG_RS12980	COG1028	Short-chain dehydrogenase reductase Sdr
FSYMDG_RS13015	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FSYMDG_RS13030	COG2801	Transposase and inactivated derivatives
FSYMDG_RS13040	COG3744	PilT protein domain protein
FSYMDG_RS13080	COG2130	NADP-dependent
FSYMDG_RS13095	COG0644	oxidoreductase
FSYMDG_RS13100	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FSYMDG_RS13120	COG0535	radical SAM domain protein
FSYMDG_RS13130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FSYMDG_RS13155	COG0411	ABC transporter
FSYMDG_RS13165	COG2963	transposase activity
FSYMDG_RS13195	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FSYMDG_RS13255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS13295	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FSYMDG_RS13300	COG2079	MmgE PrpD family protein
FSYMDG_RS13315	COG1845	cytochrome c oxidase, subunit III
FSYMDG_RS13325	COG1028	Short-chain dehydrogenase reductase Sdr
FSYMDG_RS13330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS13335	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FSYMDG_RS13340	COG2124	cytochrome p450
FSYMDG_RS13365	COG1012	belongs to the aldehyde dehydrogenase family
FSYMDG_RS13445	COG2183	response to ionizing radiation
FSYMDG_RS13460	COG3385	transposase activity
FSYMDG_RS13475	COG2801	Transposase and inactivated derivatives
FSYMDG_RS13520	COG2801	Transposase and inactivated derivatives
FSYMDG_RS13540	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FSYMDG_RS13550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS13555	COG0747	negative chemotaxis
FSYMDG_RS13560	COG0601	transmembrane transport
FSYMDG_RS13570	COG0444	Belongs to the ABC transporter superfamily
FSYMDG_RS13575	COG4608	Belongs to the ABC transporter superfamily
FSYMDG_RS13580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS13590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS13610	COG2963	transposase activity
FSYMDG_RS13615	COG2801	Transposase and inactivated derivatives
FSYMDG_RS13650	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FSYMDG_RS13670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FSYMDG_RS13695	COG0439	Biotin carboxylase
FSYMDG_RS13700	COG0511	ligase activity, forming carbon-carbon bonds
FSYMDG_RS13705	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FSYMDG_RS13705	COG0825	malonyl-CoA metabolic process
FSYMDG_RS13715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSYMDG_RS13730	COG1028	Short-chain dehydrogenase reductase Sdr
FSYMDG_RS13745	COG3385	transposase activity
FSYMDG_RS13755	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FSYMDG_RS13785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FSYMDG_RS13835	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
FSYMDG_RS13850	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
FSYMDG_RS13860	COG1013	pyruvate-flavodoxin oxidoreductase activity
FSYMDG_RS13865	COG0674	pyruvate-flavodoxin oxidoreductase activity
FSYMDG_RS13865	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FSYMDG_RS13885	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FSYMDG_RS13895	COG0070	glutamate synthase
FSYMDG_RS13895	COG0069	glutamate synthase activity
FSYMDG_RS13895	COG0067	glutamate synthase
FSYMDG_RS13900	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FSYMDG_RS13905	COG0159	tryptophan synthase activity
FSYMDG_RS13910	COG0133	tryptophan synthase activity
FSYMDG_RS13915	COG0134	indole-3-glycerol-phosphate synthase activity
FSYMDG_RS13925	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FSYMDG_RS13930	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FSYMDG_RS13940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FSYMDG_RS13970	COG1132	(ABC) transporter
FSYMDG_RS13975	COG1132	(ABC) transporter
FSYMDG_RS13980	COG0107	imidazoleglycerol-phosphate synthase activity
FSYMDG_RS13985	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FSYMDG_RS14010	COG2963	transposase activity
FSYMDG_RS14015	COG2801	Transposase and inactivated derivatives
FSYMDG_RS14040	COG1131	(ABC) transporter
FSYMDG_RS14050	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FSYMDG_RS14110	COG2124	cytochrome p450
FSYMDG_RS14120	COG0583	DNA-binding transcription factor activity
FSYMDG_RS14130	COG3842	ATPase activity
FSYMDG_RS14140	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FSYMDG_RS14150	COG2801	Transposase and inactivated derivatives
FSYMDG_RS14155	COG0395	ABC-type sugar transport system, permease component
FSYMDG_RS14180	COG2124	cytochrome p450
FSYMDG_RS14185	COG2124	cytochrome p450
FSYMDG_RS14225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSYMDG_RS14225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSYMDG_RS14240	COG1960	acyl-CoA dehydrogenase activity
FSYMDG_RS14270	COG0318	PFAM AMP-dependent synthetase and ligase
FSYMDG_RS14275	COG0439	Biotin carboxylase
FSYMDG_RS14280	COG0511	ligase activity, forming carbon-carbon bonds
FSYMDG_RS14285	COG0825	malonyl-CoA metabolic process
FSYMDG_RS14285	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FSYMDG_RS14290	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FSYMDG_RS14290	COG2070	2-Nitropropane dioxygenase
FSYMDG_RS14325	COG2963	transposase activity
FSYMDG_RS14330	COG2801	Transposase and inactivated derivatives
FSYMDG_RS14345	COG0644	oxidoreductase
FSYMDG_RS14350	COG1022	Amp-dependent synthetase and ligase
FSYMDG_RS14355	COG0477	Major facilitator Superfamily
FSYMDG_RS14375	COG1011	Hydrolase
FSYMDG_RS14385	COG0318	PFAM AMP-dependent synthetase and ligase
FSYMDG_RS14440	COG2409	Drug exporters of the RND superfamily
FSYMDG_RS14455	COG2733	membrane
FSYMDG_RS14510	COG0488	(ABC) transporter
FSYMDG_RS14530	COG2130	NADP-dependent
FSYMDG_RS14615	COG1011	Hydrolase
FSYMDG_RS14620	COG3385	transposase activity
FSYMDG_RS14680	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FSYMDG_RS14685	COG4326	sporulation control protein
FSYMDG_RS14735	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FSYMDG_RS14735	COG2308	Evidence 4 Homologs of previously reported genes of
FSYMDG_RS14740	COG1764	response to oxidative stress
FSYMDG_RS14750	COG1946	Acyl-CoA thioesterase
FSYMDG_RS14755	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FSYMDG_RS14760	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FSYMDG_RS14765	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FSYMDG_RS14785	COG1960	acyl-CoA dehydrogenase activity
FSYMDG_RS14795	COG0318	PFAM AMP-dependent synthetase and ligase
FSYMDG_RS14800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSYMDG_RS14815	COG0318	PFAM AMP-dependent synthetase and ligase
FSYMDG_RS14850	COG0183	Belongs to the thiolase family
FSYMDG_RS14855	COG1024	Enoyl-CoA hydratase
FSYMDG_RS14890	COG2885	chlorophyll binding
FSYMDG_RS14890	COG3047	cAMP biosynthetic process
FSYMDG_RS14915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FSYMDG_RS14915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FSYMDG_RS14915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FSYMDG_RS14915	COG3321	synthase
FSYMDG_RS14915	COG1028	Short-chain dehydrogenase reductase Sdr
FSYMDG_RS14925	COG2124	cytochrome p450
FSYMDG_RS14930	COG0318	PFAM AMP-dependent synthetase and ligase
FSYMDG_RS14940	COG2124	cytochrome p450
FSYMDG_RS14960	COG1695	Transcriptional regulator
FSYMDG_RS14990	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FSYMDG_RS15025	COG0463	Glycosyl transferase, family 2
FSYMDG_RS15040	COG3903	Transcriptional regulator
FSYMDG_RS15040	COG3629	intracellular signal transduction
FSYMDG_RS15055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FSYMDG_RS15060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FSYMDG_RS15065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FSYMDG_RS15070	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FSYMDG_RS15075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FSYMDG_RS15080	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FSYMDG_RS15085	COG1028	Short-chain dehydrogenase reductase Sdr
FSYMDG_RS15090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FSYMDG_RS15095	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FSYMDG_RS15105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FSYMDG_RS15125	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FSYMDG_RS15130	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FSYMDG_RS15150	COG1799	cell septum assembly
FSYMDG_RS15165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FSYMDG_RS15185	COG2337	Toxic component of a toxin-antitoxin (TA) module
FSYMDG_RS15195	COG1674	ftsk spoiiie
FSYMDG_RS15210	COG2801	Transposase and inactivated derivatives
FSYMDG_RS15300	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FSYMDG_RS15305	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FSYMDG_RS15310	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FSYMDG_RS15315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FSYMDG_RS15365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FSYMDG_RS15375	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FSYMDG_RS15380	COG0768	penicillin binding
FSYMDG_RS15390	COG0275	rRNA processing
FSYMDG_RS15395	COG2001	Belongs to the MraZ family
FSYMDG_RS15400	COG0714	Associated with various cellular activities
FSYMDG_RS15410	COG1305	Transglutaminase-like
FSYMDG_RS15450	COG0714	Associated with various cellular activities
FSYMDG_RS15460	COG2304	oxidoreductase activity
FSYMDG_RS15465	COG1278	Cold shock
FSYMDG_RS15485	COG0352	thiamine-phosphate diphosphorylase activity
FSYMDG_RS15505	COG2815	serine threonine protein kinase
FSYMDG_RS15505	COG0515	serine threonine protein kinase
FSYMDG_RS15515	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FSYMDG_RS15520	COG0205	6-phosphofructokinase activity
FSYMDG_RS15565	COG1940	carbohydrate kinase activity
FSYMDG_RS15595	COG0438	transferase activity, transferring glycosyl groups
FSYMDG_RS15680	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FSYMDG_RS15685	COG0723	plastoquinol--plastocyanin reductase activity
FSYMDG_RS15690	COG2010	Cytochrome c
FSYMDG_RS15695	COG1845	cytochrome c oxidase, subunit III
FSYMDG_RS15710	COG1592	Rubrerythrin
FSYMDG_RS15725	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FSYMDG_RS15740	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FSYMDG_RS15765	COG0425	Belongs to the sulfur carrier protein TusA family
FSYMDG_RS15770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FSYMDG_RS15780	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FSYMDG_RS15790	COG0667	Aldo Keto reductase
FSYMDG_RS15810	COG0590	tRNA wobble adenosine to inosine editing
FSYMDG_RS15815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS15820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS15835	COG4221	oxidoreductase activity
FSYMDG_RS15850	COG0596	Alpha beta hydrolase
FSYMDG_RS15865	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FSYMDG_RS15870	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FSYMDG_RS15875	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FSYMDG_RS15880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FSYMDG_RS15895	COG0515	serine threonine protein kinase
FSYMDG_RS15900	COG3340	Belongs to the peptidase S51 family
FSYMDG_RS15905	COG0321	lipoyl(octanoyl) transferase activity
FSYMDG_RS15910	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FSYMDG_RS15945	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FSYMDG_RS15960	COG0174	glutamine synthetase
FSYMDG_RS15965	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FSYMDG_RS15965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FSYMDG_RS15970	COG1309	transcriptional regulator
FSYMDG_RS15975	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FSYMDG_RS15985	COG2963	transposase activity
FSYMDG_RS15990	COG2801	Transposase and inactivated derivatives
FSYMDG_RS16000	COG2801	Transposase and inactivated derivatives
FSYMDG_RS16035	COG0494	nUDIX hydrolase
FSYMDG_RS16040	COG0504	CTP synthase activity
FSYMDG_RS16045	COG0778	Nitroreductase
FSYMDG_RS16055	COG0497	DNA recombination
FSYMDG_RS16060	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FSYMDG_RS16080	COG0647	UMP catabolic process
FSYMDG_RS16110	COG1733	regulation of RNA biosynthetic process
FSYMDG_RS16115	COG1733	regulation of RNA biosynthetic process
FSYMDG_RS16160	COG0165	Argininosuccinate lyase
FSYMDG_RS16165	COG0137	argininosuccinate synthase activity
FSYMDG_RS16170	COG1438	arginine binding
FSYMDG_RS16175	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FSYMDG_RS16180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FSYMDG_RS16185	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FSYMDG_RS16190	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FSYMDG_RS16195	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FSYMDG_RS16215	COG3220	belongs to the UPF0276 family
FSYMDG_RS16225	COG0072	phenylalanine-tRNA ligase activity
FSYMDG_RS16225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSYMDG_RS16230	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FSYMDG_RS16235	COG5002	protein histidine kinase activity
FSYMDG_RS16240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSYMDG_RS16245	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FSYMDG_RS16250	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FSYMDG_RS16255	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FSYMDG_RS16275	COG0477	Major facilitator Superfamily
FSYMDG_RS16285	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FSYMDG_RS16290	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FSYMDG_RS16290	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FSYMDG_RS16305	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FSYMDG_RS16330	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FSYMDG_RS16335	COG0242	peptide deformylase activity
FSYMDG_RS16340	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FSYMDG_RS16350	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FSYMDG_RS16360	COG1758	RNA polymerase activity
FSYMDG_RS16365	COG0194	GDP metabolic process
FSYMDG_RS16375	COG0284	orotidine-5'-phosphate decarboxylase activity
FSYMDG_RS16380	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FSYMDG_RS16385	COG0505	Belongs to the CarA family
FSYMDG_RS16395	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FSYMDG_RS16400	COG0540	Belongs to the ATCase OTCase family
FSYMDG_RS16405	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FSYMDG_RS16415	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FSYMDG_RS16420	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FSYMDG_RS16425	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FSYMDG_RS16430	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FSYMDG_RS16435	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FSYMDG_RS16440	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FSYMDG_RS16455	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FSYMDG_RS16460	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FSYMDG_RS16515	COG1028	Short-chain dehydrogenase reductase Sdr
FSYMDG_RS16535	COG2124	cytochrome p450
FSYMDG_RS16550	COG1960	acyl-CoA dehydrogenase activity
FSYMDG_RS16565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FSYMDG_RS16570	COG3835	regulator
FSYMDG_RS16580	COG1129	ABC transporter
FSYMDG_RS16595	COG0587	DNA-directed DNA polymerase activity
FSYMDG_RS16660	COG4585	Histidine kinase
FSYMDG_RS16685	COG1028	Short-chain dehydrogenase reductase Sdr
FSYMDG_RS16690	COG0747	negative chemotaxis
FSYMDG_RS16700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FSYMDG_RS16745	COG3842	ATPase activity
FSYMDG_RS16750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FSYMDG_RS16760	COG2801	Transposase and inactivated derivatives
FSYMDG_RS16770	COG3328	transposase activity
FSYMDG_RS16790	COG0523	cobalamin synthesis protein
FSYMDG_RS16805	COG2337	Toxic component of a toxin-antitoxin (TA) module
FSYMDG_RS16835	COG0583	DNA-binding transcription factor activity
FSYMDG_RS16885	COG2814	Major facilitator Superfamily
FSYMDG_RS16900	COG3629	intracellular signal transduction
FSYMDG_RS16900	COG3903	Transcriptional regulator
FSYMDG_RS16950	COG0671	phosphoesterase, PA-phosphatase related
FSYMDG_RS16970	COG2026	Addiction module toxin, RelE StbE family
FSYMDG_RS16995	COG3842	ATPase activity
FSYMDG_RS17000	COG1653	transport
FSYMDG_RS17005	COG2365	Tyrosine phosphatase family
FSYMDG_RS17020	COG0395	ABC-type sugar transport system, permease component
FSYMDG_RS17075	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FSYMDG_RS17175	COG0183	Belongs to the thiolase family
FSYMDG_RS17195	COG1012	belongs to the aldehyde dehydrogenase family
FSYMDG_RS17205	COG3629	intracellular signal transduction
FSYMDG_RS17205	COG3903	Transcriptional regulator
FSYMDG_RS17215	COG0745	RESPONSE REGULATOR receiver
FSYMDG_RS17230	COG1968	undecaprenyl-diphosphatase activity
FSYMDG_RS17240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FSYMDG_RS17250	COG0586	Pfam SNARE associated Golgi protein
FSYMDG_RS17310	COG0477	Major facilitator Superfamily
FSYMDG_RS17340	COG2361	Protein of unknown function DUF86
FSYMDG_RS17355	COG2801	Transposase and inactivated derivatives
FSYMDG_RS17375	COG0346	lactoylglutathione lyase activity
FSYMDG_RS17380	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FSYMDG_RS17445	COG1643	Atp-dependent helicase
FSYMDG_RS17450	COG0667	Aldo Keto reductase
FSYMDG_RS17480	COG3385	transposase activity
FSYMDG_RS17530	COG0484	heat shock protein binding
FSYMDG_RS17535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FSYMDG_RS17540	COG0659	secondary active sulfate transmembrane transporter activity
FSYMDG_RS17550	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FSYMDG_RS17560	COG0489	protein tyrosine kinase activity
FSYMDG_RS17570	COG2365	Tyrosine phosphatase family
FSYMDG_RS17590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FSYMDG_RS17595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FSYMDG_RS17610	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSYMDG_RS17620	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSYMDG_RS17660	COG0746	molybdenum cofactor guanylyltransferase activity
FSYMDG_RS17665	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FSYMDG_RS17690	COG1316	TRANSCRIPTIONal
FSYMDG_RS17695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FSYMDG_RS17700	COG0006	proline dipeptidase activity
FSYMDG_RS17715	COG1119	ATPase activity
FSYMDG_RS17725	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FSYMDG_RS17730	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FSYMDG_RS17740	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FSYMDG_RS17745	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FSYMDG_RS17755	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FSYMDG_RS17760	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FSYMDG_RS17765	COG2199	diguanylate cyclase activity
FSYMDG_RS17765	COG2200	EAL domain
FSYMDG_RS17765	COG2203	Gaf domain
FSYMDG_RS17770	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FSYMDG_RS17785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FSYMDG_RS17790	COG1418	mRNA catabolic process
FSYMDG_RS17795	COG2137	regulation of response to DNA damage stimulus
FSYMDG_RS17800	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FSYMDG_RS17810	COG1201	RNA secondary structure unwinding
FSYMDG_RS17820	COG1842	Phage shock protein A
FSYMDG_RS17825	COG1396	sequence-specific DNA binding
FSYMDG_RS17830	COG1058	Belongs to the CinA family
FSYMDG_RS17830	COG1546	Belongs to the CinA family
FSYMDG_RS17840	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FSYMDG_RS17860	COG1674	ftsk spoiiie
FSYMDG_RS17865	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FSYMDG_RS17870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FSYMDG_RS17880	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FSYMDG_RS17890	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FSYMDG_RS17900	COG0443	Heat shock 70 kDa protein
FSYMDG_RS17910	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FSYMDG_RS17915	COG0612	Peptidase, M16
FSYMDG_RS17920	COG1185	polyribonucleotide nucleotidyltransferase activity
FSYMDG_RS17925	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FSYMDG_RS17935	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FSYMDG_RS17940	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FSYMDG_RS17945	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FSYMDG_RS17955	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FSYMDG_RS17965	COG0779	Required for maturation of 30S ribosomal subunits
FSYMDG_RS17990	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FSYMDG_RS18005	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FSYMDG_RS18015	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FSYMDG_RS18025	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FSYMDG_RS18035	COG0233	cytoplasmic translational termination
FSYMDG_RS18040	COG0528	UMP kinase activity
FSYMDG_RS18045	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FSYMDG_RS18050	COG0052	Belongs to the universal ribosomal protein uS2 family
FSYMDG_RS18085	COG0792	nuclease activity
FSYMDG_RS18095	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FSYMDG_RS18105	COG0335	large ribosomal subunit rRNA binding
FSYMDG_RS18110	COG0336	Belongs to the RNA methyltransferase TrmD family
FSYMDG_RS18115	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FSYMDG_RS18125	COG0228	four-way junction DNA binding
FSYMDG_RS18145	COG1254	Belongs to the acylphosphatase family
FSYMDG_RS18160	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FSYMDG_RS18165	COG0571	ribonuclease III activity
FSYMDG_RS18170	COG0416	fatty acid biosynthetic process
FSYMDG_RS18190	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FSYMDG_RS18195	COG0742	ribosomal rna small subunit methyltransferase
FSYMDG_RS18205	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FSYMDG_RS18210	COG0351	phosphomethylpyrimidine kinase
FSYMDG_RS18230	COG1181	Belongs to the D-alanine--D-alanine ligase family
FSYMDG_RS18235	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FSYMDG_RS18240	COG1920	GTP binding
FSYMDG_RS18250	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FSYMDG_RS18255	COG0776	regulation of translation
FSYMDG_RS18260	COG0066	3-isopropylmalate dehydratase activity
FSYMDG_RS18265	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FSYMDG_RS18270	COG1414	Transcriptional regulator
FSYMDG_RS18275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FSYMDG_RS18285	COG2205	protein histidine kinase activity
FSYMDG_RS18305	COG2816	NAD+ diphosphatase activity
FSYMDG_RS18370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FSYMDG_RS18370	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FSYMDG_RS18400	COG0179	Fumarylacetoacetate (FAA) hydrolase
FSYMDG_RS18430	COG2226	methyltransferase
FSYMDG_RS18435	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FSYMDG_RS18465	COG1968	undecaprenyl-diphosphatase activity
FSYMDG_RS18470	COG0586	Pfam SNARE associated Golgi protein
FSYMDG_RS18495	COG0473	3-isopropylmalate dehydrogenase activity
FSYMDG_RS18500	COG2199	diguanylate cyclase activity
FSYMDG_RS18500	COG2200	EAL domain
FSYMDG_RS18505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FSYMDG_RS18520	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FSYMDG_RS18535	COG3328	transposase activity
FSYMDG_RS18550	COG0768	penicillin binding
FSYMDG_RS18555	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FSYMDG_RS18565	COG0154	amidase activity
FSYMDG_RS18570	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FSYMDG_RS18575	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FSYMDG_RS18585	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FSYMDG_RS18595	COG0482	sulfurtransferase activity
FSYMDG_RS18630	COG1703	isobutyryl-CoA mutase activity
FSYMDG_RS18630	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSYMDG_RS18630	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSYMDG_RS18635	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FSYMDG_RS18670	COG0501	Belongs to the peptidase M48B family
FSYMDG_RS18675	COG0110	maltose O-acetyltransferase activity
FSYMDG_RS18705	COG0058	SHG alpha-glucan phosphorylase activity
FSYMDG_RS18710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FSYMDG_RS18750	COG0443	Heat shock 70 kDa protein
FSYMDG_RS18775	COG0366	Alpha amylase catalytic
FSYMDG_RS18785	COG3281	Trehalose synthase
FSYMDG_RS18790	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FSYMDG_RS18805	COG2198	Histidine kinase
FSYMDG_RS18805	COG0784	Response regulator, receiver
FSYMDG_RS18805	COG2205	protein histidine kinase activity
FSYMDG_RS18815	COG0183	Belongs to the thiolase family
FSYMDG_RS18820	COG0346	lactoylglutathione lyase activity
FSYMDG_RS18865	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
FSYMDG_RS18875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FSYMDG_RS18880	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSYMDG_RS18880	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSYMDG_RS18900	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FSYMDG_RS18910	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FSYMDG_RS18915	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FSYMDG_RS18920	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FSYMDG_RS18925	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FSYMDG_RS18930	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FSYMDG_RS18935	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FSYMDG_RS18940	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FSYMDG_RS18945	COG0356	it plays a direct role in the translocation of protons across the membrane
FSYMDG_RS18965	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FSYMDG_RS18970	COG0009	L-threonylcarbamoyladenylate synthase
FSYMDG_RS18975	COG2890	protein-(glutamine-N5) methyltransferase activity
FSYMDG_RS18980	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FSYMDG_RS18985	COG0254	rRNA binding
FSYMDG_RS19000	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FSYMDG_RS19005	COG0460	homoserine dehydrogenase
FSYMDG_RS19010	COG0018	arginyl-trna synthetase
FSYMDG_RS19030	COG1131	(ABC) transporter
FSYMDG_RS19040	COG0697	spore germination
FSYMDG_RS19045	COG0535	radical SAM domain protein
FSYMDG_RS19050	COG0010	Belongs to the arginase family
FSYMDG_RS19055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FSYMDG_RS19065	COG2340	Cysteine-rich secretory protein family
FSYMDG_RS19080	COG0500	methyltransferase
FSYMDG_RS19100	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FSYMDG_RS19105	COG1686	Belongs to the peptidase S11 family
FSYMDG_RS19120	COG0644	oxidoreductase
FSYMDG_RS19145	COG0138	bifunctional purine biosynthesis protein purh
FSYMDG_RS19170	COG0045	succinate-CoA ligase (ADP-forming) activity
FSYMDG_RS19175	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSYMDG_RS19185	COG0739	heme binding
FSYMDG_RS19195	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FSYMDG_RS19200	COG0519	Catalyzes the synthesis of GMP from XMP
FSYMDG_RS19200	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FSYMDG_RS19210	COG2018	Roadblock/LC7 domain
FSYMDG_RS19240	COG0516	GMP reductase activity
FSYMDG_RS19265	COG0459	protein refolding
FSYMDG_RS19270	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FSYMDG_RS19275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FSYMDG_RS19285	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FSYMDG_RS19300	COG0802	atpase or kinase
FSYMDG_RS19310	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FSYMDG_RS19325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FSYMDG_RS19330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSYMDG_RS19335	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FSYMDG_RS19340	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FSYMDG_RS19350	COG0101	tRNA pseudouridine synthase activity
FSYMDG_RS19360	COG0203	ribosomal protein L17
FSYMDG_RS19365	COG0202	RNA polymerase activity
FSYMDG_RS19370	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FSYMDG_RS19375	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FSYMDG_RS19380	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FSYMDG_RS19385	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FSYMDG_RS19390	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FSYMDG_RS19400	COG0563	adenylate kinase activity
FSYMDG_RS19410	COG0200	Binds to the 23S rRNA
FSYMDG_RS19415	COG1841	ribosomal large subunit assembly
FSYMDG_RS19420	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FSYMDG_RS19425	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FSYMDG_RS19430	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FSYMDG_RS19435	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FSYMDG_RS19440	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FSYMDG_RS19445	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FSYMDG_RS19450	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FSYMDG_RS19455	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FSYMDG_RS19460	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FSYMDG_RS19465	COG0255	Belongs to the universal ribosomal protein uL29 family
FSYMDG_RS19470	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FSYMDG_RS19475	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FSYMDG_RS19480	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FSYMDG_RS19485	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FSYMDG_RS19490	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FSYMDG_RS19495	COG0089	rRNA binding
FSYMDG_RS19500	COG0088	Forms part of the polypeptide exit tunnel
FSYMDG_RS19505	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FSYMDG_RS19510	COG0051	transcription antitermination factor activity, RNA binding
FSYMDG_RS19515	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FSYMDG_RS19520	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FSYMDG_RS19525	COG0049	tRNA binding
FSYMDG_RS19530	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FSYMDG_RS19550	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FSYMDG_RS19555	COG0085	RNA polymerase activity
FSYMDG_RS19560	COG0222	ribosome binding
FSYMDG_RS19565	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FSYMDG_RS19570	COG0081	regulation of translation
FSYMDG_RS19575	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FSYMDG_RS19580	COG0250	Participates in transcription elongation, termination and antitermination
FSYMDG_RS19585	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FSYMDG_RS19595	COG0436	Aminotransferase
FSYMDG_RS19605	COG2030	dehydratase
FSYMDG_RS19610	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FSYMDG_RS19640	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FSYMDG_RS19655	COG1666	GTP binding
FSYMDG_RS19660	COG0501	Belongs to the peptidase M48B family
FSYMDG_RS19670	COG0674	pyruvate-flavodoxin oxidoreductase activity
FSYMDG_RS19670	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FSYMDG_RS19675	COG1013	pyruvate-flavodoxin oxidoreductase activity
FSYMDG_RS19685	COG0142	geranyltranstransferase activity
FSYMDG_RS19690	COG1007	ATP synthesis coupled electron transport
FSYMDG_RS19705	COG0713	ATP synthesis coupled electron transport
FSYMDG_RS19710	COG0839	Belongs to the complex I subunit 6 family
FSYMDG_RS19715	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSYMDG_RS19720	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FSYMDG_RS19725	COG1034	ATP synthesis coupled electron transport
FSYMDG_RS19740	COG0649	NAD binding
FSYMDG_RS19745	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSYMDG_RS19750	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSYMDG_RS19770	COG2226	methyltransferase
FSYMDG_RS19775	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FSYMDG_RS19780	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FSYMDG_RS19785	COG0492	ferredoxin-NADP+ reductase activity
FSYMDG_RS19795	COG1648	precorrin-2 dehydrogenase activity
FSYMDG_RS19795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FSYMDG_RS19800	COG0175	sulfate reduction
FSYMDG_RS19810	COG2197	response regulator
FSYMDG_RS19820	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FSYMDG_RS19835	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FSYMDG_RS19850	COG0163	prenyltransferase activity
FSYMDG_RS19860	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FSYMDG_RS19870	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FSYMDG_RS19880	COG0785	Cytochrome C biogenesis protein
FSYMDG_RS19885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSYMDG_RS19895	COG2963	transposase activity
FSYMDG_RS19900	COG2801	Transposase and inactivated derivatives
FSYMDG_RS19915	COG0406	alpha-ribazole phosphatase activity
FSYMDG_RS19920	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FSYMDG_RS19955	COG0113	porphobilinogen synthase activity
FSYMDG_RS19960	COG1648	precorrin-2 dehydrogenase activity
FSYMDG_RS19960	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FSYMDG_RS19965	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FSYMDG_RS19970	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FSYMDG_RS19985	COG1595	DNA-templated transcription, initiation
FSYMDG_RS20010	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FSYMDG_RS20020	COG2226	methyltransferase
FSYMDG_RS20025	COG1082	Xylose isomerase domain protein TIM barrel
FSYMDG_RS20030	COG0248	Ppx GppA phosphatase
FSYMDG_RS20040	COG5002	protein histidine kinase activity
FSYMDG_RS20050	COG0588	phosphoglycerate mutase activity
FSYMDG_RS20060	COG0354	folic acid binding
FSYMDG_RS20080	COG1196	nuclear chromosome segregation
FSYMDG_RS20095	COG0667	Aldo Keto reductase
FSYMDG_RS20105	COG0438	transferase activity, transferring glycosyl groups
FSYMDG_RS20115	COG4044	May play a role in the intracellular transport of hydrophobic ligands
FSYMDG_RS20160	COG0745	RESPONSE REGULATOR receiver
FSYMDG_RS20170	COG0456	acetyltransferase
FSYMDG_RS20175	COG0745	RESPONSE REGULATOR receiver
FSYMDG_RS20180	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FSYMDG_RS20200	COG1366	Belongs to the anti-sigma-factor antagonist family
FSYMDG_RS20225	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FSYMDG_RS20245	COG0783	Belongs to the Dps family
FSYMDG_RS20265	COG3385	transposase activity
FSYMDG_RS20310	COG2963	transposase activity
FSYMDG_RS20315	COG2801	Transposase and inactivated derivatives
FSYMDG_RS20325	COG0124	histidyl-tRNA synthetase
FSYMDG_RS20330	COG0563	adenylate kinase activity
FSYMDG_RS20345	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FSYMDG_RS20355	COG0315	cyclic pyranopterin monophosphate synthase activity
FSYMDG_RS20360	COG0315	cyclic pyranopterin monophosphate synthase activity
FSYMDG_RS20360	COG0521	Mo-molybdopterin cofactor biosynthetic process
FSYMDG_RS20365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FSYMDG_RS20400	COG0640	Transcriptional regulator
FSYMDG_RS20430	COG1320	monovalent cation:proton antiporter activity
FSYMDG_RS20450	COG3385	transposase activity
FSYMDG_RS20455	COG2801	Transposase and inactivated derivatives
FSYMDG_RS20460	COG2963	transposase activity
FSYMDG_RS20560	COG2205	protein histidine kinase activity
FSYMDG_RS20565	COG0745	RESPONSE REGULATOR receiver
FSYMDG_RS20600	COG2890	protein-(glutamine-N5) methyltransferase activity
FSYMDG_RS20615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FSYMDG_RS20620	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FSYMDG_RS20635	COG2814	Major facilitator Superfamily
FSYMDG_RS20655	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSYMDG_RS20685	COG1129	ABC transporter
FSYMDG_RS20710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FSYMDG_RS20715	COG1121	(ABC) transporter
FSYMDG_RS20720	COG0803	Belongs to the bacterial solute-binding protein 9 family
FSYMDG_RS20730	COG1028	Short-chain dehydrogenase reductase Sdr
FSYMDG_RS20735	COG1733	regulation of RNA biosynthetic process
FSYMDG_RS20760	COG2801	Transposase and inactivated derivatives
FSYMDG_RS20765	COG2124	cytochrome p450
FSYMDG_RS20780	COG2208	phosphoserine phosphatase activity
FSYMDG_RS20780	COG1366	Belongs to the anti-sigma-factor antagonist family
FSYMDG_RS20780	COG2172	sigma factor antagonist activity
FSYMDG_RS20795	COG1960	acyl-CoA dehydrogenase activity
FSYMDG_RS20825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FSYMDG_RS20850	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FSYMDG_RS20870	COG2814	Major facilitator Superfamily
FSYMDG_RS20890	COG1309	transcriptional regulator
FSYMDG_RS20905	COG3511	phospholipase C
FSYMDG_RS20910	COG1126	abc transporter atp-binding protein
FSYMDG_RS20915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FSYMDG_RS20920	COG0765	amino acid transport
FSYMDG_RS20925	COG0765	amino acid transport
FSYMDG_RS20930	COG2175	clavaminate synthase activity
FSYMDG_RS20955	COG1136	(ABC) transporter
FSYMDG_RS20960	COG1136	(ABC) transporter
FSYMDG_RS20960	COG0577	efflux transmembrane transporter activity
FSYMDG_RS21000	COG1556	Lactate utilization protein
FSYMDG_RS21010	COG0247	lactate metabolic process
FSYMDG_RS21040	COG0215	cysteine-tRNA ligase activity
FSYMDG_RS21050	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FSYMDG_RS21060	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FSYMDG_RS21065	COG1329	Transcriptional regulator
FSYMDG_RS21080	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FSYMDG_RS21085	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FSYMDG_RS21090	COG1194	a g-specific adenine glycosylase
FSYMDG_RS21100	COG0442	prolyl-tRNA aminoacylation
FSYMDG_RS21125	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FSYMDG_RS21155	COG1111	helicase
FSYMDG_RS21155	COG1205	dead DEAH box helicase
FSYMDG_RS21205	COG0596	Alpha beta hydrolase
FSYMDG_RS21245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FSYMDG_RS21270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSYMDG_RS21280	COG1408	metallophosphoesterase
FSYMDG_RS21335	COG1366	Belongs to the anti-sigma-factor antagonist family
FSYMDG_RS21345	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FSYMDG_RS21350	COG1754	DNA topoisomerase type I activity
FSYMDG_RS21350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FSYMDG_RS21355	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FSYMDG_RS21365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FSYMDG_RS21375	COG0598	Magnesium transport protein CorA
FSYMDG_RS21390	COG1388	LysM domain
FSYMDG_RS21390	COG0791	NLP P60 protein
FSYMDG_RS21390	COG3103	Sh3 type 3 domain protein
FSYMDG_RS21400	COG1846	Transcriptional regulator
FSYMDG_RS21405	COG1492	cobalamin metabolic process
FSYMDG_RS21410	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FSYMDG_RS21420	COG0590	tRNA wobble adenosine to inosine editing
FSYMDG_RS21465	COG0494	nUDIX hydrolase
FSYMDG_RS21535	COG0076	glutamate decarboxylase activity
FSYMDG_RS21545	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FSYMDG_RS21560	COG0151	Belongs to the GarS family
FSYMDG_RS21570	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FSYMDG_RS21575	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FSYMDG_RS21580	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FSYMDG_RS21585	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FSYMDG_RS21590	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FSYMDG_RS21600	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FSYMDG_RS21615	COG1999	signal sequence binding
FSYMDG_RS21630	COG0463	Glycosyl transferase, family 2
FSYMDG_RS21635	COG4303	Ethanolamine ammonia lyase large subunit
FSYMDG_RS21815	COG1215	transferase activity, transferring glycosyl groups
FSYMDG_RS21825	COG3385	transposase activity
FSYMDG_RS21845	COG0459	protein refolding
FSYMDG_RS21940	COG1121	(ABC) transporter
FSYMDG_RS21965	COG0022	dehydrogenase e1 component
FSYMDG_RS21970	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSYMDG_RS21980	COG1960	acyl-CoA dehydrogenase activity
FSYMDG_RS22010	COG0166	Belongs to the GPI family
FSYMDG_RS22020	COG0515	serine threonine protein kinase
FSYMDG_RS22020	COG2815	serine threonine protein kinase
FSYMDG_RS22025	COG0741	lytic transglycosylase activity
FSYMDG_RS22025	COG1196	nuclear chromosome segregation
FSYMDG_RS22025	COG0739	heme binding
FSYMDG_RS22100	COG3572	ergothioneine biosynthetic process
FSYMDG_RS22105	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FSYMDG_RS22115	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FSYMDG_RS22120	COG0129	dihydroxy-acid dehydratase activity
FSYMDG_RS22160	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FSYMDG_RS22165	COG1595	DNA-templated transcription, initiation
FSYMDG_RS22175	COG0305	Participates in initiation and elongation during chromosome replication
FSYMDG_RS22180	COG0359	binds to the 23S rRNA
FSYMDG_RS22185	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FSYMDG_RS22195	COG0360	Binds together with S18 to 16S ribosomal RNA
FSYMDG_RS22235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSYMDG_RS22245	COG1695	Transcriptional regulator
FSYMDG_RS22270	COG0617	tRNA 3'-terminal CCA addition
FSYMDG_RS22285	COG0728	peptidoglycan biosynthetic process
FSYMDG_RS22305	COG0492	ferredoxin-NADP+ reductase activity
FSYMDG_RS22310	COG3118	belongs to the thioredoxin family
FSYMDG_RS22315	COG3409	Peptidoglycan-binding domain 1 protein
FSYMDG_RS22315	COG0860	N-Acetylmuramoyl-L-alanine amidase
FSYMDG_RS22330	COG1192	Involved in chromosome partitioning
FSYMDG_RS22335	COG0357	Ribosomal RNA small subunit methyltransferase G
FSYMDG_RS22405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FSYMDG_RS22455	COG0745	RESPONSE REGULATOR receiver
FSYMDG_RS22465	COG5001	Diguanylate cyclase
FSYMDG_RS22465	COG3300	MHYT domain
FSYMDG_RS22480	COG1309	transcriptional regulator
FSYMDG_RS22505	COG3173	Aminoglycoside phosphotransferase
FSYMDG_RS22535	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FSYMDG_RS22615	COG2340	Cysteine-rich secretory protein family
FSYMDG_RS22630	COG0515	serine threonine protein kinase
FSYMDG_RS22715	COG0443	Heat shock 70 kDa protein
FSYMDG_RS22765	COG0515	serine threonine protein kinase
FSYMDG_RS22770	COG0829	nickel cation binding
FSYMDG_RS22820	COG3321	synthase
FSYMDG_RS22820	COG1028	Short-chain dehydrogenase reductase Sdr
FSYMDG_RS22820	COG0604	alcohol dehydrogenase
FSYMDG_RS22855	COG2815	serine threonine protein kinase
FSYMDG_RS22855	COG0515	serine threonine protein kinase
FSYMDG_RS22865	COG0629	single-stranded DNA binding
FSYMDG_RS22890	COG0419	ATPase involved in DNA repair
FSYMDG_RS22900	COG2319	Wd-40 repeat
FSYMDG_RS22900	COG5635	Nacht domain
FSYMDG_RS22910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FSYMDG_RS22930	COG2151	metal-sulfur cluster biosynthetic enzyme
FSYMDG_RS22980	COG2046	Belongs to the sulfate adenylyltransferase family
FSYMDG_RS22980	COG0529	Catalyzes the synthesis of activated sulfate
FSYMDG_RS23005	COG3311	Transcriptional regulator
FSYMDG_RS23015	COG1396	sequence-specific DNA binding
FSYMDG_RS23035	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FSYMDG_RS23035	COG0574	Belongs to the PEP-utilizing enzyme family
FSYMDG_RS23095	COG0438	transferase activity, transferring glycosyl groups
FSYMDG_RS23120	COG0791	NLP P60 protein
FSYMDG_RS23135	COG0444	Belongs to the ABC transporter superfamily
FSYMDG_RS23195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSYMDG_RS23205	COG1902	pentaerythritol trinitrate reductase activity
FSYMDG_RS23205	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSYMDG_RS23255	COG2197	response regulator
FSYMDG_RS23260	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FSYMDG_RS23275	COG0515	serine threonine protein kinase
FSYMDG_RS23275	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FSYMDG_RS23305	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FSYMDG_RS23360	COG2094	Belongs to the DNA glycosylase MPG family
FSYMDG_RS23395	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FSYMDG_RS23400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSYMDG_RS23405	COG1846	Transcriptional regulator
FSYMDG_RS23415	COG1136	(ABC) transporter
FSYMDG_RS23435	COG0515	serine threonine protein kinase
FSYMDG_RS23440	COG0083	homoserine kinase activity
FSYMDG_RS23455	COG1132	(ABC) transporter
FSYMDG_RS23465	COG0506	proline dehydrogenase activity
FSYMDG_RS23530	COG2172	sigma factor antagonist activity
FSYMDG_RS23590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain