locus-tag	class	description
AX769_RS00025	COG1070	Carbohydrate kinase
AX769_RS00030	COG3347	Dehydrogenase
AX769_RS00030	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS00040	COG1879	ABC-type sugar transport system periplasmic component
AX769_RS00045	COG1172	Belongs to the binding-protein-dependent transport system permease family
AX769_RS00050	COG1172	Belongs to the binding-protein-dependent transport system permease family
AX769_RS00055	COG1129	ABC transporter
AX769_RS00060	COG1609	Transcriptional regulator
AX769_RS00070	COG2814	Major facilitator Superfamily
AX769_RS00115	COG2814	Major facilitator Superfamily
AX769_RS00130	COG0477	Major facilitator Superfamily
AX769_RS00160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AX769_RS00175	COG0542	response to heat
AX769_RS00180	COG2814	Major facilitator Superfamily
AX769_RS00195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AX769_RS00210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AX769_RS00220	COG1012	belongs to the aldehyde dehydrogenase family
AX769_RS00250	COG1846	Transcriptional regulator
AX769_RS00260	COG1957	nucleoside hydrolase
AX769_RS00265	COG1012	belongs to the aldehyde dehydrogenase family
AX769_RS00300	COG1252	NADH dehydrogenase
AX769_RS00320	COG3940	Belongs to the glycosyl hydrolase 43 family
AX769_RS00325	COG1396	sequence-specific DNA binding
AX769_RS00345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AX769_RS00405	COG0667	Aldo Keto reductase
AX769_RS00415	COG0515	serine threonine protein kinase
AX769_RS00440	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AX769_RS00465	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AX769_RS00480	COG1902	pentaerythritol trinitrate reductase activity
AX769_RS00490	COG2814	Major facilitator Superfamily
AX769_RS00495	COG1609	Transcriptional regulator
AX769_RS00530	COG2272	Belongs to the type-B carboxylesterase lipase family
AX769_RS00575	COG1609	Transcriptional regulator
AX769_RS00610	COG1940	carbohydrate kinase activity
AX769_RS00620	COG2814	Major facilitator Superfamily
AX769_RS00625	COG2188	Transcriptional regulator
AX769_RS00650	COG0667	Aldo Keto reductase
AX769_RS00685	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AX769_RS00690	COG0183	Belongs to the thiolase family
AX769_RS00695	COG1414	Transcriptional regulator
AX769_RS00710	COG1454	alcohol dehydrogenase
AX769_RS00715	COG3485	protocatechuate 3,4-dioxygenase
AX769_RS00730	COG2409	Drug exporters of the RND superfamily
AX769_RS00745	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AX769_RS00760	COG1268	BioY protein
AX769_RS00765	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AX769_RS00775	COG1131	(ABC) transporter
AX769_RS00825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AX769_RS00850	COG0179	Fumarylacetoacetate (FAA) hydrolase
AX769_RS00895	COG2197	response regulator
AX769_RS00900	COG2261	transglycosylase associated protein
AX769_RS00915	COG2814	Major facilitator Superfamily
AX769_RS00920	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS00925	COG2207	Transcriptional regulator
AX769_RS00930	COG0657	acetylesterase activity
AX769_RS00950	COG1129	ABC transporter
AX769_RS00970	COG0657	acetylesterase activity
AX769_RS00985	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS01030	COG2207	Transcriptional regulator
AX769_RS01120	COG0438	transferase activity, transferring glycosyl groups
AX769_RS01140	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AX769_RS01150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AX769_RS01155	COG0477	Major facilitator Superfamily
AX769_RS01160	COG1309	transcriptional regulator
AX769_RS01170	COG1063	alcohol dehydrogenase
AX769_RS01185	COG0488	(ABC) transporter
AX769_RS01190	COG1309	transcriptional regulator
AX769_RS01215	COG1612	heme a metabolic process
AX769_RS01250	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AX769_RS01285	COG1316	TRANSCRIPTIONal
AX769_RS01295	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AX769_RS01300	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AX769_RS01340	COG0535	radical SAM domain protein
AX769_RS01350	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS01355	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS01360	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS01365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AX769_RS01400	COG1733	regulation of RNA biosynthetic process
AX769_RS01410	COG1802	Transcriptional regulator
AX769_RS01415	COG0477	Major facilitator Superfamily
AX769_RS01435	COG0515	serine threonine protein kinase
AX769_RS01440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AX769_RS01445	COG0640	Transcriptional regulator
AX769_RS01450	COG0640	Transcriptional regulator
AX769_RS01470	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS01520	COG0300	oxidoreductase activity
AX769_RS01525	COG5646	InterPro IPR014922
AX769_RS01535	COG0561	phosphatase activity
AX769_RS01540	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AX769_RS01545	COG1597	lipid kinase activity
AX769_RS01550	COG0077	Prephenate dehydratase
AX769_RS01565	COG0277	FAD linked oxidase domain protein
AX769_RS01570	COG0204	Acyl-transferase
AX769_RS01570	COG0318	PFAM AMP-dependent synthetase and ligase
AX769_RS01575	COG0300	oxidoreductase activity
AX769_RS01605	COG0714	Associated with various cellular activities
AX769_RS01635	COG0477	Major facilitator Superfamily
AX769_RS01645	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AX769_RS01660	COG0095	Lipoate-protein ligase
AX769_RS01680	COG2814	Major facilitator Superfamily
AX769_RS01700	COG1305	Transglutaminase-like
AX769_RS01710	COG2308	Evidence 4 Homologs of previously reported genes of
AX769_RS01720	COG2261	transglycosylase associated protein
AX769_RS01740	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AX769_RS01745	COG0302	gtp cyclohydrolase
AX769_RS01760	COG2084	Dehydrogenase
AX769_RS01780	COG0514	ATP-dependent DNA helicase (RecQ)
AX769_RS01800	COG0419	ATPase involved in DNA repair
AX769_RS01805	COG0420	3'-5' exonuclease activity
AX769_RS01825	COG0601	transmembrane transport
AX769_RS01860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AX769_RS01870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AX769_RS01875	COG0438	transferase activity, transferring glycosyl groups
AX769_RS01890	COG0513	Belongs to the DEAD box helicase family
AX769_RS01895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AX769_RS01900	COG0531	amino acid
AX769_RS01905	COG1609	Transcriptional regulator
AX769_RS01920	COG0395	ABC-type sugar transport system, permease component
AX769_RS01925	COG3340	Belongs to the peptidase S51 family
AX769_RS01950	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AX769_RS01980	COG0151	Belongs to the GarS family
AX769_RS01985	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AX769_RS02010	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AX769_RS02020	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AX769_RS02035	COG1605	Chorismate mutase
AX769_RS02035	COG0287	Prephenate dehydrogenase
AX769_RS02045	COG1764	response to oxidative stress
AX769_RS02075	COG0673	inositol 2-dehydrogenase activity
AX769_RS02085	COG0673	inositol 2-dehydrogenase activity
AX769_RS02090	COG0395	ABC-type sugar transport system, permease component
AX769_RS02120	COG0673	inositol 2-dehydrogenase activity
AX769_RS02125	COG2115	Belongs to the xylose isomerase family
AX769_RS02130	COG1070	Carbohydrate kinase
AX769_RS02150	COG3336	cytochrome c oxidase
AX769_RS02155	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AX769_RS02160	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AX769_RS02170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AX769_RS02205	COG0534	Mate efflux family protein
AX769_RS02275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AX769_RS02280	COG3206	protein involved in exopolysaccharide biosynthesis
AX769_RS02280	COG0489	protein tyrosine kinase activity
AX769_RS02305	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AX769_RS02325	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AX769_RS02330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AX769_RS02350	COG0438	transferase activity, transferring glycosyl groups
AX769_RS02390	COG0673	inositol 2-dehydrogenase activity
AX769_RS02395	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AX769_RS02400	COG0542	response to heat
AX769_RS02435	COG2813	Specifically methylates the guanine in position
AX769_RS02470	COG0789	Transcriptional regulator
AX769_RS02475	COG0484	heat shock protein binding
AX769_RS02480	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AX769_RS02485	COG0443	Heat shock 70 kDa protein
AX769_RS02520	COG4552	Acetyltransferase involved in intracellular survival and related
AX769_RS02535	COG1295	ribonuclease BN
AX769_RS02575	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AX769_RS02580	COG0717	Belongs to the dCTP deaminase family
AX769_RS02585	COG0604	alcohol dehydrogenase
AX769_RS02585	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS02585	COG3321	synthase
AX769_RS02615	COG1595	DNA-templated transcription, initiation
AX769_RS02635	COG0431	NADPH-dependent FMN reductase
AX769_RS02660	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AX769_RS02690	COG0387	Pfam Sodium calcium exchanger
AX769_RS02700	COG1953	Uracil, thiamine, allantoin
AX769_RS02710	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AX769_RS02740	COG0038	chloride channel
AX769_RS02755	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AX769_RS02770	COG4152	abc transporter atp-binding protein
AX769_RS02785	COG0454	-acetyltransferase
AX769_RS02805	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AX769_RS02820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AX769_RS02825	COG3336	cytochrome c oxidase
AX769_RS02830	COG0776	regulation of translation
AX769_RS02835	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AX769_RS02840	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AX769_RS02845	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AX769_RS02855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AX769_RS02870	COG1136	(ABC) transporter
AX769_RS02870	COG0577	efflux transmembrane transporter activity
AX769_RS02875	COG1136	(ABC) transporter
AX769_RS02875	COG0577	efflux transmembrane transporter activity
AX769_RS02895	COG4585	Histidine kinase
AX769_RS02900	COG2197	response regulator
AX769_RS02905	COG1131	(ABC) transporter
AX769_RS02915	COG0508	dehydrogenase complex catalyzes the overall conversion of
AX769_RS02935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AX769_RS02940	COG1950	PFAM Membrane protein of
AX769_RS02950	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AX769_RS02990	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AX769_RS03010	COG3046	protein related to deoxyribodipyrimidine photolyase
AX769_RS03025	COG0477	Major facilitator Superfamily
AX769_RS03030	COG2267	carboxylic ester hydrolase activity
AX769_RS03040	COG0791	NLP P60 protein
AX769_RS03040	COG3883	PFAM NLP P60 protein
AX769_RS03045	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS03055	COG2315	Protein conserved in bacteria
AX769_RS03065	COG1309	transcriptional regulator
AX769_RS03070	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS03085	COG0590	tRNA wobble adenosine to inosine editing
AX769_RS03090	COG2351	hydroxyisourate hydrolase activity
AX769_RS03105	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AX769_RS03160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AX769_RS03180	COG0154	amidase activity
AX769_RS03190	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AX769_RS03205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AX769_RS03215	COG2814	Major facilitator Superfamily
AX769_RS03235	COG0583	DNA-binding transcription factor activity
AX769_RS03240	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AX769_RS03245	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AX769_RS03250	COG1854	S-ribosylhomocysteine lyase activity
AX769_RS03255	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AX769_RS03265	COG0667	Aldo Keto reductase
AX769_RS03275	COG2814	Major facilitator Superfamily
AX769_RS03285	COG1309	transcriptional regulator
AX769_RS03290	COG0166	Belongs to the GPI family
AX769_RS03295	COG2188	Transcriptional regulator
AX769_RS03440	COG2814	Major facilitator Superfamily
AX769_RS03485	COG0393	Putative heavy-metal-binding
AX769_RS03505	COG2267	carboxylic ester hydrolase activity
AX769_RS03525	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AX769_RS03535	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AX769_RS03545	COG0745	RESPONSE REGULATOR receiver
AX769_RS03570	COG3842	ATPase activity
AX769_RS03655	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AX769_RS03660	COG0823	Involved in the tonB-independent uptake of proteins
AX769_RS03670	COG0673	inositol 2-dehydrogenase activity
AX769_RS03675	COG1609	Transcriptional regulator
AX769_RS03685	COG2211	Major facilitator Superfamily
AX769_RS03690	COG0673	inositol 2-dehydrogenase activity
AX769_RS03705	COG1609	Transcriptional regulator
AX769_RS03710	COG0395	ABC-type sugar transport system, permease component
AX769_RS03715	COG1175	transmembrane transport
AX769_RS03730	COG1309	transcriptional regulator
AX769_RS03740	COG1309	transcriptional regulator
AX769_RS03745	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS03760	COG0583	DNA-binding transcription factor activity
AX769_RS03775	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AX769_RS03780	COG3052	prosthetic group binding
AX769_RS03805	COG3321	synthase
AX769_RS03805	COG0604	alcohol dehydrogenase
AX769_RS03815	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS03840	COG3619	membrane
AX769_RS03870	COG4585	Histidine kinase
AX769_RS03890	COG4585	Histidine kinase
AX769_RS03895	COG2197	response regulator
AX769_RS03900	COG3548	integral membrane protein
AX769_RS03920	COG0667	Aldo Keto reductase
AX769_RS03950	COG0395	ABC-type sugar transport system, permease component
AX769_RS03955	COG1175	transmembrane transport
AX769_RS03985	COG1472	Belongs to the glycosyl hydrolase 3 family
AX769_RS04010	COG2207	Transcriptional regulator
AX769_RS04015	COG5290	Psort location Cytoplasmic, score
AX769_RS04090	COG0305	Participates in initiation and elongation during chromosome replication
AX769_RS04095	COG0359	binds to the 23S rRNA
AX769_RS04100	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AX769_RS04110	COG0360	Binds together with S18 to 16S ribosomal RNA
AX769_RS04115	COG0617	tRNA 3'-terminal CCA addition
AX769_RS04130	COG0492	ferredoxin-NADP+ reductase activity
AX769_RS04135	COG3118	belongs to the thioredoxin family
AX769_RS04140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AX769_RS04165	COG1192	Involved in chromosome partitioning
AX769_RS04170	COG0357	Ribosomal RNA small subunit methyltransferase G
AX769_RS04180	COG0706	membrane insertase activity
AX769_RS04185	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AX769_RS04190	COG0594	ribonuclease P activity
AX769_RS04195	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AX769_RS04205	COG0592	DNA-directed DNA polymerase activity
AX769_RS04210	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AX769_RS04215	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AX769_RS04220	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
AX769_RS04225	COG0187	DNA topoisomerase II activity
AX769_RS04270	COG3764	Sortase (surface protein transpeptidase)
AX769_RS04280	COG0515	serine threonine protein kinase
AX769_RS04280	COG2815	serine threonine protein kinase
AX769_RS04285	COG0515	serine threonine protein kinase
AX769_RS04290	COG0768	penicillin binding
AX769_RS04305	COG1716	ATPase activity
AX769_RS04310	COG1716	ATPase activity
AX769_RS04335	COG1247	-acetyltransferase
AX769_RS04340	COG0321	lipoyl(octanoyl) transferase activity
AX769_RS04350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AX769_RS04355	COG0477	Major facilitator Superfamily
AX769_RS04360	COG1957	nucleoside hydrolase
AX769_RS04365	COG1609	Transcriptional regulator
AX769_RS04370	COG2267	carboxylic ester hydrolase activity
AX769_RS04415	COG0673	inositol 2-dehydrogenase activity
AX769_RS04465	COG0477	Major facilitator Superfamily
AX769_RS04470	COG0372	Belongs to the citrate synthase family
AX769_RS04475	COG0372	Belongs to the citrate synthase family
AX769_RS04490	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AX769_RS04500	COG2135	peptidase activity
AX769_RS04520	COG2807	transmembrane transport
AX769_RS04540	COG0738	Major facilitator superfamily
AX769_RS04555	COG2233	PERMEase
AX769_RS04560	COG3590	peptidase
AX769_RS04585	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AX769_RS04595	COG2130	NADP-dependent
AX769_RS04600	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AX769_RS04630	COG3253	May function as heme-dependent peroxidase
AX769_RS04635	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AX769_RS04640	COG0181	hydroxymethylbilane synthase activity
AX769_RS04650	COG0113	porphobilinogen synthase activity
AX769_RS04655	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AX769_RS04665	COG1119	ATPase activity
AX769_RS04670	COG1802	Transcriptional regulator
AX769_RS04675	COG1802	Transcriptional regulator
AX769_RS04685	COG0604	alcohol dehydrogenase
AX769_RS04715	COG1054	Belongs to the UPF0176 family
AX769_RS04745	COG1834	amidinotransferase
AX769_RS04750	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AX769_RS04770	COG0739	heme binding
AX769_RS04770	COG0741	lytic transglycosylase activity
AX769_RS04770	COG1196	nuclear chromosome segregation
AX769_RS04780	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AX769_RS04785	COG0037	tRNA processing
AX769_RS04795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AX769_RS04805	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AX769_RS04810	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AX769_RS04835	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AX769_RS04845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AX769_RS04875	COG0622	Phosphoesterase
AX769_RS04890	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AX769_RS04900	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AX769_RS04915	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AX769_RS04940	COG3328	transposase activity
AX769_RS04950	COG4974	Belongs to the 'phage' integrase family
AX769_RS04970	COG1609	Transcriptional regulator
AX769_RS04975	COG0366	Alpha amylase catalytic
AX769_RS04985	COG1175	transmembrane transport
AX769_RS04990	COG0395	ABC-type sugar transport system, permease component
AX769_RS05000	COG2814	Major facilitator Superfamily
AX769_RS05025	COG0076	glutamate decarboxylase activity
AX769_RS05035	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS05055	COG4335	DNA alkylation repair
AX769_RS05085	COG2814	Major facilitator Superfamily
AX769_RS05095	COG2072	flavoprotein involved in K transport
AX769_RS05130	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AX769_RS05135	COG0303	'Molybdopterin
AX769_RS05145	COG0746	molybdenum cofactor guanylyltransferase activity
AX769_RS05150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AX769_RS05180	COG0842	Transport permease protein
AX769_RS05185	COG4585	Histidine kinase
AX769_RS05190	COG2197	response regulator
AX769_RS05300	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AX769_RS05305	COG1201	RNA secondary structure unwinding
AX769_RS05310	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AX769_RS05315	COG0667	Aldo Keto reductase
AX769_RS05325	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS05330	COG3265	gluconokinase activity
AX769_RS05390	COG0604	alcohol dehydrogenase
AX769_RS05405	COG0513	Belongs to the DEAD box helicase family
AX769_RS05450	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AX769_RS05455	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AX769_RS05460	COG4786	Flagellar basal body rod
AX769_RS05460	COG1256	bacterial-type flagellum assembly
AX769_RS05510	COG1677	Flagellar hook-basal body complex protein FliE
AX769_RS05515	COG1766	The M ring may be actively involved in energy transduction
AX769_RS05520	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AX769_RS05530	COG1157	protein secretion by the type III secretion system
AX769_RS05535	COG0791	NLP P60 protein
AX769_RS05545	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AX769_RS05560	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AX769_RS05565	COG1360	Flagellar Motor Protein
AX769_RS05585	COG1338	Plays a role in the flagellum-specific transport system
AX769_RS05600	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AX769_RS05605	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AX769_RS05620	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AX769_RS05675	COG0596	Alpha beta hydrolase
AX769_RS05685	COG3321	synthase
AX769_RS05685	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS05685	COG0604	alcohol dehydrogenase
AX769_RS05690	COG1733	regulation of RNA biosynthetic process
AX769_RS05715	COG0477	Major facilitator Superfamily
AX769_RS05840	COG1233	COG1233 Phytoene dehydrogenase and related
AX769_RS05880	COG4221	oxidoreductase activity
AX769_RS05885	COG0300	oxidoreductase activity
AX769_RS05900	COG0085	RNA polymerase activity
AX769_RS05920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AX769_RS05930	COG1459	type II secretion system
AX769_RS05955	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AX769_RS05980	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AX769_RS05985	COG0049	tRNA binding
AX769_RS05990	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AX769_RS06015	COG0051	transcription antitermination factor activity, RNA binding
AX769_RS06025	COG0088	Forms part of the polypeptide exit tunnel
AX769_RS06030	COG0089	rRNA binding
AX769_RS06035	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AX769_RS06040	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AX769_RS06045	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AX769_RS06050	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AX769_RS06055	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AX769_RS06060	COG0255	Belongs to the universal ribosomal protein uL29 family
AX769_RS06065	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AX769_RS06070	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AX769_RS06075	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AX769_RS06080	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AX769_RS06085	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AX769_RS06090	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AX769_RS06095	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AX769_RS06100	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AX769_RS06105	COG1841	ribosomal large subunit assembly
AX769_RS06110	COG0200	Binds to the 23S rRNA
AX769_RS06120	COG0563	adenylate kinase activity
AX769_RS06125	COG0024	Methionine aminopeptidase
AX769_RS06130	COG1316	TRANSCRIPTIONal
AX769_RS06135	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AX769_RS06140	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AX769_RS06145	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AX769_RS06150	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AX769_RS06155	COG0202	RNA polymerase activity
AX769_RS06160	COG0203	ribosomal protein L17
AX769_RS06165	COG0101	tRNA pseudouridine synthase activity
AX769_RS06170	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AX769_RS06175	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AX769_RS06180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AX769_RS06205	COG1072	(Pantothenic acid kinase))
AX769_RS06210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AX769_RS06215	COG0736	holo-[acyl-carrier-protein] synthase activity
AX769_RS06220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AX769_RS06225	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AX769_RS06230	COG0802	atpase or kinase
AX769_RS06270	COG0456	acetyltransferase
AX769_RS06270	COG1214	PFAM Peptidase M22, glycoprotease
AX769_RS06275	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AX769_RS06290	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AX769_RS06315	COG0516	GMP reductase activity
AX769_RS06320	COG0475	glutathione-regulated potassium exporter activity
AX769_RS06335	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AX769_RS06335	COG0519	Catalyzes the synthesis of GMP from XMP
AX769_RS06375	COG0045	succinate-CoA ligase (ADP-forming) activity
AX769_RS06395	COG0138	bifunctional purine biosynthesis protein purh
AX769_RS06410	COG1132	(ABC) transporter
AX769_RS06415	COG1132	(ABC) transporter
AX769_RS06430	COG1940	carbohydrate kinase activity
AX769_RS06440	COG1175	transmembrane transport
AX769_RS06445	COG3833	ABC-type maltose transport systems, permease component
AX769_RS06455	COG3547	Transposase (IS116 IS110 IS902 family)
AX769_RS06465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AX769_RS06465	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AX769_RS06490	COG2838	Isocitrate dehydrogenase
AX769_RS06505	COG2182	Extracellular solute-binding protein
AX769_RS06510	COG1175	transmembrane transport
AX769_RS06515	COG3833	ABC-type maltose transport systems, permease component
AX769_RS06520	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AX769_RS06525	COG0363	glucosamine-6-phosphate deaminase activity
AX769_RS06530	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AX769_RS06535	COG1070	Carbohydrate kinase
AX769_RS06540	COG0277	FAD linked oxidase domain protein
AX769_RS06550	COG2223	nitrite transmembrane transporter activity
AX769_RS06575	COG1846	Transcriptional regulator
AX769_RS06575	COG1940	carbohydrate kinase activity
AX769_RS06585	COG1175	transmembrane transport
AX769_RS06590	COG0395	ABC-type sugar transport system, permease component
AX769_RS06595	COG1486	melibiose metabolic process
AX769_RS06610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AX769_RS06615	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AX769_RS06640	COG0477	Major facilitator Superfamily
AX769_RS06675	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AX769_RS06680	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AX769_RS06685	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AX769_RS06690	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AX769_RS06700	COG1349	DNA-binding transcription factor activity
AX769_RS06735	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AX769_RS06750	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AX769_RS06765	COG0454	-acetyltransferase
AX769_RS06765	COG0456	acetyltransferase
AX769_RS06770	COG0745	RESPONSE REGULATOR receiver
AX769_RS06780	COG4044	May play a role in the intracellular transport of hydrophobic ligands
AX769_RS06785	COG0354	folic acid binding
AX769_RS06795	COG0588	phosphoglycerate mutase activity
AX769_RS06825	COG4214	carbohydrate transport
AX769_RS06840	COG0704	Plays a role in the regulation of phosphate uptake
AX769_RS06845	COG5002	protein histidine kinase activity
AX769_RS06860	COG1329	Transcriptional regulator
AX769_RS06865	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AX769_RS06865	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AX769_RS06870	COG0215	cysteine-tRNA ligase activity
AX769_RS06885	COG3842	ATPase activity
AX769_RS06925	COG1063	alcohol dehydrogenase
AX769_RS06950	COG1309	transcriptional regulator
AX769_RS06955	COG1012	belongs to the aldehyde dehydrogenase family
AX769_RS06960	COG0179	Fumarylacetoacetate (FAA) hydrolase
AX769_RS06980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AX769_RS06985	COG0492	ferredoxin-NADP+ reductase activity
AX769_RS07000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AX769_RS07010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AX769_RS07035	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AX769_RS07055	COG1278	Cold shock
AX769_RS07060	COG0459	protein refolding
AX769_RS07065	COG5002	protein histidine kinase activity
AX769_RS07065	COG5000	phosphorelay sensor kinase activity
AX769_RS07070	COG0745	RESPONSE REGULATOR receiver
AX769_RS07090	COG1278	Cold shock
AX769_RS07100	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AX769_RS07110	COG0791	NLP P60 protein
AX769_RS07125	COG0149	triose-phosphate isomerase activity
AX769_RS07130	COG0667	Aldo Keto reductase
AX769_RS07140	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS07180	COG0640	Transcriptional regulator
AX769_RS07200	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AX769_RS07240	COG1137	ATPase activity
AX769_RS07255	COG1309	transcriptional regulator
AX769_RS07260	COG1960	acyl-CoA dehydrogenase activity
AX769_RS07275	COG1024	Enoyl-CoA hydratase
AX769_RS07285	COG0318	PFAM AMP-dependent synthetase and ligase
AX769_RS07300	COG0183	Belongs to the thiolase family
AX769_RS07305	COG1946	Acyl-CoA thioesterase
AX769_RS07315	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AX769_RS07340	COG1129	ABC transporter
AX769_RS07345	COG1172	Belongs to the binding-protein-dependent transport system permease family
AX769_RS07365	COG1012	belongs to the aldehyde dehydrogenase family
AX769_RS07390	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AX769_RS07395	COG2079	MmgE PrpD family protein
AX769_RS07440	COG2837	iron assimilation
AX769_RS07445	COG2822	iron ion transport
AX769_RS07470	COG2188	Transcriptional regulator
AX769_RS07475	COG1942	4-Oxalocrotonate Tautomerase
AX769_RS07480	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AX769_RS07485	COG1082	Xylose isomerase domain protein TIM barrel
AX769_RS07500	COG3962	Belongs to the TPP enzyme family
AX769_RS07520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AX769_RS07525	COG0673	inositol 2-dehydrogenase activity
AX769_RS07580	COG2197	response regulator
AX769_RS07585	COG0583	DNA-binding transcription factor activity
AX769_RS07610	COG0402	S-adenosylhomocysteine deaminase activity
AX769_RS07615	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AX769_RS07655	COG2197	response regulator
AX769_RS07680	COG0393	Putative heavy-metal-binding
AX769_RS07695	COG1090	epimerase
AX769_RS07705	COG3422	double-strand break repair
AX769_RS07725	COG2205	protein histidine kinase activity
AX769_RS07730	COG0745	RESPONSE REGULATOR receiver
AX769_RS07745	COG1136	(ABC) transporter
AX769_RS07755	COG1970	mechanosensitive ion channel activity
AX769_RS07770	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AX769_RS07800	COG2890	protein-(glutamine-N5) methyltransferase activity
AX769_RS07810	COG0328	RNA-DNA hybrid ribonuclease activity
AX769_RS07815	COG0656	L-ascorbic acid biosynthetic process
AX769_RS07840	COG1609	Transcriptional regulator
AX769_RS07870	COG0395	ABC-type sugar transport system, permease component
AX769_RS07880	COG1780	Probably involved in ribonucleotide reductase function
AX769_RS07885	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AX769_RS07890	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AX769_RS07910	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AX769_RS07935	COG0765	amino acid transport
AX769_RS07940	COG1126	abc transporter atp-binding protein
AX769_RS07945	COG3328	transposase activity
AX769_RS07955	COG1175	transmembrane transport
AX769_RS07960	COG0395	ABC-type sugar transport system, permease component
AX769_RS07990	COG1609	Transcriptional regulator
AX769_RS07995	COG1643	Atp-dependent helicase
AX769_RS08015	COG0318	PFAM AMP-dependent synthetase and ligase
AX769_RS08020	COG1331	Highly conserved protein containing a thioredoxin domain
AX769_RS08035	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AX769_RS08045	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AX769_RS08060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AX769_RS08080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AX769_RS08085	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AX769_RS08110	COG3585	molybdate ion transport
AX769_RS08135	COG0745	RESPONSE REGULATOR receiver
AX769_RS08140	COG2205	protein histidine kinase activity
AX769_RS08160	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AX769_RS08175	COG0521	Mo-molybdopterin cofactor biosynthetic process
AX769_RS08180	COG0314	molybdopterin synthase activity
AX769_RS08210	COG1309	transcriptional regulator
AX769_RS08275	COG1595	DNA-templated transcription, initiation
AX769_RS08355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AX769_RS08360	COG0004	ammonium transporteR
AX769_RS08380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AX769_RS08395	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AX769_RS08400	COG0363	glucosamine-6-phosphate deaminase activity
AX769_RS08405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AX769_RS08420	COG2188	Transcriptional regulator
AX769_RS08440	COG4608	Belongs to the ABC transporter superfamily
AX769_RS08460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AX769_RS08465	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AX769_RS08475	COG2814	Major facilitator Superfamily
AX769_RS08480	COG2207	Transcriptional regulator
AX769_RS08490	COG1129	ABC transporter
AX769_RS08495	COG1172	Belongs to the binding-protein-dependent transport system permease family
AX769_RS08500	COG0457	Tetratricopeptide repeat
AX769_RS08505	COG1063	alcohol dehydrogenase
AX769_RS08520	COG2814	Major facilitator Superfamily
AX769_RS08525	COG2936	dipeptidyl-peptidase activity
AX769_RS08550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AX769_RS08565	COG2814	Major facilitator Superfamily
AX769_RS08575	COG1846	Transcriptional regulator
AX769_RS08580	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AX769_RS08585	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AX769_RS08610	COG1116	anion transmembrane transporter activity
AX769_RS08620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AX769_RS08625	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AX769_RS08635	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AX769_RS08640	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AX769_RS08645	COG0193	aminoacyl-tRNA hydrolase activity
AX769_RS08655	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AX769_RS08670	COG0148	phosphopyruvate hydratase activity
AX769_RS08700	COG0501	Belongs to the peptidase M48B family
AX769_RS08705	COG1704	LemA family
AX769_RS08720	COG0745	RESPONSE REGULATOR receiver
AX769_RS08725	COG5002	protein histidine kinase activity
AX769_RS08730	COG3214	Protein conserved in bacteria
AX769_RS08740	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AX769_RS08745	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AX769_RS08755	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AX769_RS08770	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AX769_RS08780	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AX769_RS08805	COG1722	exodeoxyribonuclease VII activity
AX769_RS08810	COG1570	exodeoxyribonuclease VII activity
AX769_RS08815	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AX769_RS08825	COG0191	fructose-bisphosphate aldolase activity
AX769_RS08845	COG1322	Protein conserved in bacteria
AX769_RS08910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AX769_RS08925	COG2409	Drug exporters of the RND superfamily
AX769_RS08965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AX769_RS08980	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AX769_RS09010	COG1902	pentaerythritol trinitrate reductase activity
AX769_RS09030	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AX769_RS09035	COG0509	glycine decarboxylation via glycine cleavage system
AX769_RS09060	COG0601	transmembrane transport
AX769_RS09065	COG0444	Belongs to the ABC transporter superfamily
AX769_RS09070	COG4608	Belongs to the ABC transporter superfamily
AX769_RS09075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AX769_RS09080	COG1217	gtp-binding protein TYPA
AX769_RS09085	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AX769_RS09130	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AX769_RS09145	COG2239	Acts as a magnesium transporter
AX769_RS09150	COG0006	proline dipeptidase activity
AX769_RS09165	COG0513	Belongs to the DEAD box helicase family
AX769_RS09190	COG0210	DNA helicase
AX769_RS09205	COG0210	DNA helicase
AX769_RS09215	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AX769_RS09220	COG1615	UPF0182 protein
AX769_RS09230	COG0800	Aldolase
AX769_RS09245	COG0673	inositol 2-dehydrogenase activity
AX769_RS09250	COG1940	carbohydrate kinase activity
AX769_RS09255	COG4821	SIS domain
AX769_RS09265	COG1735	metal-dependent hydrolase with the TIM-barrel fold
AX769_RS09275	COG1653	transport
AX769_RS09280	COG1175	transmembrane transport
AX769_RS09315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AX769_RS09365	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AX769_RS09370	COG1131	(ABC) transporter
AX769_RS09390	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AX769_RS09395	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AX769_RS09400	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AX769_RS09415	COG0482	sulfurtransferase activity
AX769_RS09430	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AX769_RS09435	COG0154	amidase activity
AX769_RS09460	COG1335	isochorismatase
AX769_RS09465	COG2197	response regulator
AX769_RS09485	COG2755	lipolytic protein G-D-S-L family
AX769_RS09490	COG0590	tRNA wobble adenosine to inosine editing
AX769_RS09525	COG0246	Mannitol dehydrogenase
AX769_RS09535	COG0673	inositol 2-dehydrogenase activity
AX769_RS09545	COG0395	ABC-type sugar transport system, permease component
AX769_RS09560	COG1609	Transcriptional regulator
AX769_RS09565	COG1904	glucuronate isomerase
AX769_RS09575	COG4221	oxidoreductase activity
AX769_RS09605	COG2353	YceI-like domain
AX769_RS09610	COG0667	Aldo Keto reductase
AX769_RS09630	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AX769_RS09685	COG4721	ABC-type cobalt transport system, permease component
AX769_RS09690	COG4172	Belongs to the ABC transporter superfamily
AX769_RS09700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AX769_RS09715	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AX769_RS09740	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AX769_RS09765	COG3961	Belongs to the TPP enzyme family
AX769_RS09770	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AX769_RS09795	COG1946	Acyl-CoA thioesterase
AX769_RS09815	COG0668	transmembrane transport
AX769_RS09840	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AX769_RS09845	COG0698	ribose 5-phosphate isomerase
AX769_RS09925	COG0544	peptidyl-prolyl cis-trans isomerase activity
AX769_RS09930	COG0740	serine-type endopeptidase activity
AX769_RS09935	COG0740	serine-type endopeptidase activity
AX769_RS09940	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AX769_RS10020	COG1285	pathogenesis
AX769_RS10030	COG0659	secondary active sulfate transmembrane transporter activity
AX769_RS10035	COG1733	regulation of RNA biosynthetic process
AX769_RS10040	COG0667	Aldo Keto reductase
AX769_RS10090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AX769_RS10100	COG4166	transmembrane transport
AX769_RS10105	COG0477	Major facilitator Superfamily
AX769_RS10115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AX769_RS10130	COG1309	transcriptional regulator
AX769_RS10155	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AX769_RS10160	COG0285	dihydrofolate synthase activity
AX769_RS10170	COG0105	UTP biosynthetic process
AX769_RS10185	COG1530	ribonuclease E activity
AX769_RS10205	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AX769_RS10210	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AX769_RS10215	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AX769_RS10220	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AX769_RS10225	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AX769_RS10235	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AX769_RS10245	COG0799	negative regulation of ribosome biogenesis
AX769_RS10265	COG0489	protein tyrosine kinase activity
AX769_RS10270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AX769_RS10310	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS10325	COG0110	maltose O-acetyltransferase activity
AX769_RS10335	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AX769_RS10340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AX769_RS10360	COG1316	TRANSCRIPTIONal
AX769_RS10375	COG0406	alpha-ribazole phosphatase activity
AX769_RS10400	COG0702	epimerase
AX769_RS10405	COG2030	dehydratase
AX769_RS10405	COG1012	belongs to the aldehyde dehydrogenase family
AX769_RS10445	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS10450	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AX769_RS10460	COG3387	PFAM Glycoside hydrolase 15-related
AX769_RS10475	COG0783	Belongs to the Dps family
AX769_RS10500	COG0723	plastoquinol--plastocyanin reductase activity
AX769_RS10505	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AX769_RS10530	COG0028	Belongs to the TPP enzyme family
AX769_RS10570	COG0494	nUDIX hydrolase
AX769_RS10615	COG0025	NhaP-type Na H and K H
AX769_RS10620	COG2272	Belongs to the type-B carboxylesterase lipase family
AX769_RS10655	COG4591	ABC-type transport system involved in lipoprotein release permease component
AX769_RS10655	COG1136	(ABC) transporter
AX769_RS10660	COG0577	efflux transmembrane transporter activity
AX769_RS10680	COG1063	alcohol dehydrogenase
AX769_RS10695	COG1027	Aspartate ammonia-lyase
AX769_RS10715	COG0545	Peptidyl-prolyl cis-trans isomerase
AX769_RS10740	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AX769_RS10760	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AX769_RS10765	COG2271	Major facilitator Superfamily
AX769_RS10775	COG0318	PFAM AMP-dependent synthetase and ligase
AX769_RS10785	COG1185	polyribonucleotide nucleotidyltransferase activity
AX769_RS10790	COG0667	Aldo Keto reductase
AX769_RS10795	COG1309	transcriptional regulator
AX769_RS10800	COG0612	Peptidase, M16
AX769_RS10805	COG0406	alpha-ribazole phosphatase activity
AX769_RS10815	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AX769_RS10830	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AX769_RS10835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AX769_RS10840	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AX769_RS10845	COG1674	ftsk spoiiie
AX769_RS10855	COG1546	Belongs to the CinA family
AX769_RS10855	COG1058	Belongs to the CinA family
AX769_RS10860	COG1396	sequence-specific DNA binding
AX769_RS10870	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AX769_RS10875	COG2137	regulation of response to DNA damage stimulus
AX769_RS10880	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AX769_RS10885	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AX769_RS10890	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AX769_RS10895	COG2813	Specifically methylates the guanine in position
AX769_RS10900	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AX769_RS10910	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AX769_RS10920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AX769_RS10925	COG0131	Imidazoleglycerol-phosphate dehydratase
AX769_RS10930	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AX769_RS10935	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AX769_RS10950	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AX769_RS10955	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AX769_RS10960	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AX769_RS10975	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AX769_RS10980	COG0072	phenylalanine-tRNA ligase activity
AX769_RS10980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AX769_RS10990	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AX769_RS10995	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AX769_RS11005	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AX769_RS11010	COG0165	Argininosuccinate lyase
AX769_RS11015	COG2094	Belongs to the DNA glycosylase MPG family
AX769_RS11020	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AX769_RS11045	COG0647	UMP catabolic process
AX769_RS11055	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AX769_RS11060	COG0497	DNA recombination
AX769_RS11065	COG0395	ABC-type sugar transport system, permease component
AX769_RS11085	COG1609	Transcriptional regulator
AX769_RS11090	COG0504	CTP synthase activity
AX769_RS11095	COG0494	nUDIX hydrolase
AX769_RS11115	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AX769_RS11130	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AX769_RS11135	COG1160	GTP binding
AX769_RS11225	COG0514	ATP-dependent DNA helicase (RecQ)
AX769_RS11240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AX769_RS11250	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AX769_RS11315	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AX769_RS11350	COG2314	TM2 domain
AX769_RS11355	COG4221	oxidoreductase activity
AX769_RS11365	COG3328	transposase activity
AX769_RS11405	COG3654	unkown
AX769_RS11415	COG1397	ADP-ribosylglycohydrolase
AX769_RS11435	COG1131	(ABC) transporter
AX769_RS11475	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS11480	COG2272	Belongs to the type-B carboxylesterase lipase family
AX769_RS11505	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AX769_RS11505	COG2308	Evidence 4 Homologs of previously reported genes of
AX769_RS11510	COG0367	asparagine synthase
AX769_RS11550	COG1793	dna ligase
AX769_RS11580	COG0318	PFAM AMP-dependent synthetase and ligase
AX769_RS11595	COG1960	acyl-CoA dehydrogenase activity
AX769_RS11600	COG0183	Belongs to the thiolase family
AX769_RS11635	COG0318	PFAM AMP-dependent synthetase and ligase
AX769_RS11640	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS11650	COG0640	Transcriptional regulator
AX769_RS11705	COG0656	L-ascorbic acid biosynthetic process
AX769_RS11775	COG0667	Aldo Keto reductase
AX769_RS11790	COG0667	Aldo Keto reductase
AX769_RS11795	COG0667	Aldo Keto reductase
AX769_RS11810	COG0371	Dehydrogenase
AX769_RS11815	COG0484	heat shock protein binding
AX769_RS11840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AX769_RS11845	COG1716	ATPase activity
AX769_RS11860	COG1192	Involved in chromosome partitioning
AX769_RS11865	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AX769_RS11880	COG1940	carbohydrate kinase activity
AX769_RS11890	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AX769_RS11895	COG2815	serine threonine protein kinase
AX769_RS11895	COG0515	serine threonine protein kinase
AX769_RS11900	COG3942	CHAP domain
AX769_RS11900	COG1388	LysM domain
AX769_RS11910	COG0142	geranyltranstransferase activity
AX769_RS11920	COG2001	Belongs to the MraZ family
AX769_RS11925	COG0275	rRNA processing
AX769_RS11935	COG0768	penicillin binding
AX769_RS11940	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AX769_RS11950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AX769_RS11955	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AX769_RS11965	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AX769_RS11970	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AX769_RS11975	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AX769_RS11985	COG1799	cell septum assembly
AX769_RS11995	COG3599	regulation of cell shape
AX769_RS12000	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AX769_RS12010	COG0587	DNA-directed DNA polymerase activity
AX769_RS12015	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AX769_RS12020	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AX769_RS12025	COG0167	dihydroorotate dehydrogenase activity
AX769_RS12035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AX769_RS12045	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AX769_RS12050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AX769_RS12060	COG0656	L-ascorbic acid biosynthetic process
AX769_RS12065	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AX769_RS12070	COG0723	plastoquinol--plastocyanin reductase activity
AX769_RS12075	COG2010	Cytochrome c
AX769_RS12080	COG1845	cytochrome c oxidase, subunit III
AX769_RS12085	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AX769_RS12095	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AX769_RS12100	COG2376	Dihydroxyacetone kinase
AX769_RS12115	COG3012	SEC-C Motif Domain Protein
AX769_RS12135	COG0671	phosphoesterase, PA-phosphatase related
AX769_RS12140	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AX769_RS12165	COG0477	Major facilitator Superfamily
AX769_RS12175	COG1309	transcriptional regulator
AX769_RS12190	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS12215	COG0300	oxidoreductase activity
AX769_RS12240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AX769_RS12255	COG0745	RESPONSE REGULATOR receiver
AX769_RS12260	COG2205	protein histidine kinase activity
AX769_RS12285	COG1309	transcriptional regulator
AX769_RS12295	COG2197	response regulator
AX769_RS12315	COG0463	Glycosyl transferase, family 2
AX769_RS12320	COG1051	belongs to the nudix hydrolase family
AX769_RS12325	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS12350	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AX769_RS12355	COG4581	dead DEAH box helicase
AX769_RS12360	COG0805	protein transport
AX769_RS12380	COG0545	Peptidyl-prolyl cis-trans isomerase
AX769_RS12390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AX769_RS12405	COG0215	cysteine-tRNA ligase activity
AX769_RS12410	COG1968	undecaprenyl-diphosphatase activity
AX769_RS12415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AX769_RS12465	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AX769_RS12475	COG2267	carboxylic ester hydrolase activity
AX769_RS12490	COG2197	response regulator
AX769_RS12500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AX769_RS12510	COG2376	Dihydroxyacetone kinase
AX769_RS12515	COG0667	Aldo Keto reductase
AX769_RS12520	COG1252	NADH dehydrogenase
AX769_RS12530	COG0438	transferase activity, transferring glycosyl groups
AX769_RS12560	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AX769_RS12570	COG2755	lipolytic protein G-D-S-L family
AX769_RS12605	COG0366	Alpha amylase catalytic
AX769_RS12615	COG1396	sequence-specific DNA binding
AX769_RS12625	COG0254	rRNA binding
AX769_RS12630	COG1119	ATPase activity
AX769_RS12635	COG0297	glycogen (starch) synthase activity
AX769_RS12640	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AX769_RS12645	COG3830	Belongs to the UPF0237 family
AX769_RS12645	COG0560	Phosphoserine phosphatase
AX769_RS12675	COG0488	(ABC) transporter
AX769_RS12680	COG1268	BioY protein
AX769_RS12685	COG2151	metal-sulfur cluster biosynthetic enzyme
AX769_RS12690	COG0396	ATPase activity
AX769_RS12720	COG0109	protoheme IX farnesyltransferase activity
AX769_RS12730	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AX769_RS12735	COG0166	Belongs to the GPI family
AX769_RS12750	COG0363	glucosamine-6-phosphate deaminase activity
AX769_RS12760	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AX769_RS12770	COG0126	phosphoglycerate kinase activity
AX769_RS12785	COG1481	regulation of sporulation
AX769_RS12790	COG1660	Displays ATPase and GTPase activities
AX769_RS12795	COG0322	excinuclease ABC activity
AX769_RS12810	COG0556	nucleotide-excision repair
AX769_RS12815	COG0237	dephospho-CoA kinase activity
AX769_RS12820	COG0539	negative regulation of cytoplasmic translation
AX769_RS12840	COG2050	protein possibly involved in aromatic compounds catabolism
AX769_RS12855	COG1278	Cold shock
AX769_RS12880	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AX769_RS12885	COG0159	tryptophan synthase activity
AX769_RS12890	COG0133	tryptophan synthase activity
AX769_RS12895	COG0134	indole-3-glycerol-phosphate synthase activity
AX769_RS12915	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AX769_RS12920	COG0107	imidazoleglycerol-phosphate synthase activity
AX769_RS12925	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AX769_RS12930	COG0140	phosphoribosyl-ATP diphosphatase activity
AX769_RS12935	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AX769_RS12955	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AX769_RS12960	COG1758	RNA polymerase activity
AX769_RS12965	COG0194	GDP metabolic process
AX769_RS12970	COG0284	orotidine-5'-phosphate decarboxylase activity
AX769_RS12975	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AX769_RS12980	COG0505	Belongs to the CarA family
AX769_RS12990	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AX769_RS12995	COG0540	Belongs to the ATCase OTCase family
AX769_RS13000	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AX769_RS13005	COG1764	response to oxidative stress
AX769_RS13010	COG1846	Transcriptional regulator
AX769_RS13020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AX769_RS13025	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AX769_RS13050	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS13070	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AX769_RS13075	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AX769_RS13080	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AX769_RS13085	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AX769_RS13100	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AX769_RS13105	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AX769_RS13115	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AX769_RS13130	COG1196	nuclear chromosome segregation
AX769_RS13140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AX769_RS13150	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AX769_RS13155	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AX769_RS13165	COG2255	four-way junction helicase activity
AX769_RS13170	COG0632	four-way junction helicase activity
AX769_RS13175	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AX769_RS13180	COG0217	transcriptional regulatory protein
AX769_RS13185	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AX769_RS13200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AX769_RS13210	COG0702	epimerase
AX769_RS13235	COG0740	serine-type endopeptidase activity
AX769_RS13240	COG0740	serine-type endopeptidase activity
AX769_RS13325	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AX769_RS13340	COG0756	dUTP diphosphatase activity
AX769_RS13360	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AX769_RS13365	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AX769_RS13370	COG1960	acyl-CoA dehydrogenase activity
AX769_RS13375	COG0187	DNA topoisomerase II activity
AX769_RS13390	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AX769_RS13395	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AX769_RS13405	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AX769_RS13410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AX769_RS13415	COG0508	dehydrogenase complex catalyzes the overall conversion of
AX769_RS13445	COG4221	oxidoreductase activity
AX769_RS13450	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AX769_RS13460	COG1215	transferase activity, transferring glycosyl groups
AX769_RS13475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AX769_RS13475	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AX769_RS13510	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AX769_RS13540	COG0277	FAD linked oxidase domain protein
AX769_RS13550	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AX769_RS13550	COG0456	acetyltransferase
AX769_RS13565	COG0442	prolyl-tRNA aminoacylation
AX769_RS13570	COG0488	(ABC) transporter
AX769_RS13580	COG1012	belongs to the aldehyde dehydrogenase family
AX769_RS13600	COG0076	glutamate decarboxylase activity
AX769_RS13605	COG0531	amino acid
AX769_RS13615	COG0531	amino acid
AX769_RS13620	COG2235	arginine
AX769_RS13625	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AX769_RS13680	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AX769_RS13700	COG2838	Isocitrate dehydrogenase
AX769_RS13720	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AX769_RS13735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AX769_RS13740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AX769_RS13745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AX769_RS13780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AX769_RS13790	COG1609	Transcriptional regulator
AX769_RS13810	COG2814	Major facilitator Superfamily
AX769_RS13815	COG1846	Transcriptional regulator
AX769_RS13835	COG1674	ftsk spoiiie
AX769_RS13890	COG4977	sequence-specific DNA binding
AX769_RS13900	COG0138	bifunctional purine biosynthesis protein purh
AX769_RS13995	COG0714	Associated with various cellular activities
AX769_RS14005	COG2815	serine threonine protein kinase
AX769_RS14005	COG0515	serine threonine protein kinase
AX769_RS14030	COG0297	glycogen (starch) synthase activity
AX769_RS14040	COG0242	peptide deformylase activity
AX769_RS14050	COG4585	Histidine kinase
AX769_RS14055	COG2197	response regulator
AX769_RS14070	COG4608	Belongs to the ABC transporter superfamily
AX769_RS14075	COG0358	DNA primase activity
AX769_RS14110	COG0423	glycine-tRNA ligase activity
AX769_RS14130	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AX769_RS14135	COG1381	Involved in DNA repair and RecF pathway recombination
AX769_RS14140	COG2860	membrane
AX769_RS14145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AX769_RS14150	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AX769_RS14160	COG2197	response regulator
AX769_RS14165	COG4585	Histidine kinase
AX769_RS14170	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AX769_RS14180	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AX769_RS14190	COG0537	adenosine 5'-monophosphoramidase activity
AX769_RS14200	COG0484	heat shock protein binding
AX769_RS14205	COG1420	regulation of RNA biosynthetic process
AX769_RS14220	COG4762	Protein conserved in bacteria
AX769_RS14225	COG0481	GTPase activity
AX769_RS14230	COG0436	Aminotransferase
AX769_RS14235	COG0268	Binds directly to 16S ribosomal RNA
AX769_RS14260	COG1596	polysaccharide export
AX769_RS14260	COG1555	photosystem II stabilization
AX769_RS14265	COG0495	leucyl-tRNA aminoacylation
AX769_RS14295	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AX769_RS14300	COG4988	ABC transporter
AX769_RS14305	COG1294	oxidase, subunit
AX769_RS14310	COG1271	oxidase subunit
AX769_RS14320	COG1174	glycine betaine transport
AX769_RS14325	COG1174	glycine betaine transport
AX769_RS14340	COG2135	peptidase activity
AX769_RS14365	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AX769_RS14375	COG3387	PFAM Glycoside hydrolase 15-related
AX769_RS14380	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AX769_RS14385	COG0587	DNA-directed DNA polymerase activity
AX769_RS14390	COG0435	Glutathione S-transferase
AX769_RS14420	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AX769_RS14425	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AX769_RS14455	COG0196	riboflavin kinase activity
AX769_RS14470	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AX769_RS14485	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AX769_RS14490	COG3266	domain, Protein
AX769_RS14490	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AX769_RS14505	COG0442	prolyl-tRNA aminoacylation
AX769_RS14535	COG0714	Associated with various cellular activities
AX769_RS14540	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AX769_RS14545	COG0750	zinc metalloprotease
AX769_RS14585	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AX769_RS14590	COG0545	Peptidyl-prolyl cis-trans isomerase
AX769_RS14625	COG0714	Associated with various cellular activities
AX769_RS14640	COG0631	protein serine/threonine phosphatase activity
AX769_RS14650	COG3022	response to hydroperoxide
AX769_RS14655	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AX769_RS14660	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AX769_RS14665	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AX769_RS14670	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AX769_RS14675	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AX769_RS14680	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AX769_RS14685	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AX769_RS14690	COG0356	it plays a direct role in the translocation of protons across the membrane
AX769_RS14700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AX769_RS14710	COG2890	protein-(glutamine-N5) methyltransferase activity
AX769_RS14715	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AX769_RS14735	COG0460	homoserine dehydrogenase
AX769_RS14750	COG0018	arginyl-trna synthetase
AX769_RS14760	COG0259	pyridoxamine-phosphate oxidase activity
AX769_RS14780	COG1842	Phage shock protein A
AX769_RS14795	COG3237	CsbD-like
AX769_RS14820	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AX769_RS14830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AX769_RS14835	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AX769_RS14840	COG1120	ATPase activity
AX769_RS14885	COG0747	negative chemotaxis
AX769_RS14890	COG0601	transmembrane transport
AX769_RS14895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AX769_RS14980	COG3340	Belongs to the peptidase S51 family
AX769_RS14985	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AX769_RS14995	COG0277	FAD linked oxidase domain protein
AX769_RS15010	COG1305	Transglutaminase-like
AX769_RS15045	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AX769_RS15055	COG1609	Transcriptional regulator
AX769_RS15060	COG1175	transmembrane transport
AX769_RS15065	COG0395	ABC-type sugar transport system, permease component
AX769_RS15105	COG2814	Major facilitator Superfamily
AX769_RS15130	COG1902	pentaerythritol trinitrate reductase activity
AX769_RS15140	COG1253	flavin adenine dinucleotide binding
AX769_RS15150	COG0508	dehydrogenase complex catalyzes the overall conversion of
AX769_RS15150	COG0567	Dehydrogenase, E1 component
AX769_RS15165	COG1595	DNA-templated transcription, initiation
AX769_RS15170	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AX769_RS15185	COG0701	Predicted permease
AX769_RS15190	COG0745	RESPONSE REGULATOR receiver
AX769_RS15195	COG2205	protein histidine kinase activity
AX769_RS15210	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AX769_RS15215	COG2177	Part of the ABC transporter FtsEX involved in
AX769_RS15220	COG2884	Cell division ATP-binding protein ftsE
AX769_RS15225	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AX769_RS15250	COG0366	Alpha amylase catalytic
AX769_RS15255	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AX769_RS15260	COG2409	Drug exporters of the RND superfamily
AX769_RS15265	COG3118	belongs to the thioredoxin family
AX769_RS15280	COG0628	permease
AX769_RS15310	COG0233	cytoplasmic translational termination
AX769_RS15315	COG0528	UMP kinase activity
AX769_RS15320	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AX769_RS15325	COG0052	Belongs to the universal ribosomal protein uS2 family
AX769_RS15330	COG0477	Major facilitator Superfamily
AX769_RS15340	COG4974	Belongs to the 'phage' integrase family
AX769_RS15360	COG0792	nuclease activity
AX769_RS15370	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AX769_RS15375	COG0681	Belongs to the peptidase S26 family
AX769_RS15380	COG0335	large ribosomal subunit rRNA binding
AX769_RS15385	COG0024	Methionine aminopeptidase
AX769_RS15390	COG0336	Belongs to the RNA methyltransferase TrmD family
AX769_RS15395	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AX769_RS15400	COG1837	Belongs to the UPF0109 family
AX769_RS15405	COG0228	four-way junction DNA binding
AX769_RS15425	COG1960	acyl-CoA dehydrogenase activity
AX769_RS15435	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AX769_RS15440	COG0583	DNA-binding transcription factor activity
AX769_RS15445	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS15470	COG0406	alpha-ribazole phosphatase activity
AX769_RS15490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AX769_RS15495	COG0571	ribonuclease III activity
AX769_RS15500	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AX769_RS15505	COG1399	metal-binding, possibly nucleic acid-binding protein
AX769_RS15525	COG0714	Associated with various cellular activities
AX769_RS15530	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AX769_RS15565	COG1181	Belongs to the D-alanine--D-alanine ligase family
AX769_RS15570	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AX769_RS15580	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AX769_RS15590	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AX769_RS15640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AX769_RS15645	COG0473	3-isopropylmalate dehydrogenase activity
AX769_RS15665	COG0246	Mannitol dehydrogenase
AX769_RS15675	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AX769_RS15680	COG0440	acetolactate synthase activity
AX769_RS15685	COG0028	Belongs to the TPP enzyme family
AX769_RS15690	COG0129	dihydroxy-acid dehydratase activity
AX769_RS15715	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AX769_RS15725	COG0598	Magnesium transport protein CorA
AX769_RS15760	COG0386	Belongs to the glutathione peroxidase family
AX769_RS15765	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AX769_RS15770	COG2814	Major facilitator Superfamily
AX769_RS15780	COG4106	trans-aconitate 2-methyltransferase activity
AX769_RS15790	COG0477	Major facilitator Superfamily
AX769_RS15795	COG2367	Beta-lactamase
AX769_RS15810	COG0596	Alpha beta hydrolase
AX769_RS15830	COG0604	alcohol dehydrogenase
AX769_RS15830	COG3321	synthase
AX769_RS15850	COG0656	L-ascorbic acid biosynthetic process
AX769_RS15905	COG2723	6-phospho-beta-galactosidase activity
AX769_RS15910	COG4172	Belongs to the ABC transporter superfamily
AX769_RS15920	COG0601	transmembrane transport
AX769_RS15930	COG1609	Transcriptional regulator
AX769_RS15935	COG0366	Alpha amylase catalytic
AX769_RS15945	COG1177	transmembrane transport
AX769_RS15950	COG1176	ABC-type spermidine putrescine transport system, permease component I
AX769_RS15960	COG3842	ATPase activity
AX769_RS15965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AX769_RS15980	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS15985	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AX769_RS16005	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS16020	COG0300	oxidoreductase activity
AX769_RS16030	COG0667	Aldo Keto reductase
AX769_RS16035	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AX769_RS16050	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AX769_RS16070	COG4221	oxidoreductase activity
AX769_RS16075	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AX769_RS16095	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AX769_RS16100	COG1674	ftsk spoiiie
AX769_RS16105	COG1584	GPR1 FUN34 yaaH family protein
AX769_RS16130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AX769_RS16135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AX769_RS16140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AX769_RS16145	COG4172	Belongs to the ABC transporter superfamily
AX769_RS16160	COG0747	negative chemotaxis
AX769_RS16175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AX769_RS16190	COG3118	belongs to the thioredoxin family
AX769_RS16230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AX769_RS16250	COG0747	negative chemotaxis
AX769_RS16255	COG0765	amino acid transport
AX769_RS16260	COG1126	abc transporter atp-binding protein
AX769_RS16290	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AX769_RS16300	COG0686	Belongs to the AlaDH PNT family
AX769_RS16305	COG2364	Membrane
AX769_RS16360	COG0640	Transcriptional regulator
AX769_RS16375	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS16390	COG1802	Transcriptional regulator
AX769_RS16405	COG1175	transmembrane transport
AX769_RS16410	COG0395	ABC-type sugar transport system, permease component
AX769_RS16420	COG2814	Major facilitator Superfamily
AX769_RS16425	COG0667	Aldo Keto reductase
AX769_RS16445	COG0596	Alpha beta hydrolase
AX769_RS16460	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS16485	COG0500	methyltransferase
AX769_RS16505	COG0277	FAD linked oxidase domain protein
AX769_RS16565	COG3152	Membrane
AX769_RS16610	COG0596	Alpha beta hydrolase
AX769_RS16615	COG1609	Transcriptional regulator
AX769_RS16625	COG0395	ABC-type sugar transport system, permease component
AX769_RS16630	COG1175	transmembrane transport
AX769_RS16635	COG2182	Extracellular solute-binding protein
AX769_RS16655	COG0189	ligase activity
AX769_RS16680	COG1609	Transcriptional regulator
AX769_RS16685	COG1064	alcohol dehydrogenase
AX769_RS16690	COG0076	glutamate decarboxylase activity
AX769_RS16695	COG1136	(ABC) transporter
AX769_RS16700	COG1136	(ABC) transporter
AX769_RS16745	COG0768	penicillin binding
AX769_RS16760	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS16765	COG0667	Aldo Keto reductase
AX769_RS16805	COG2378	regulation of single-species biofilm formation
AX769_RS16820	COG2409	Drug exporters of the RND superfamily
AX769_RS16830	COG1673	EVE domain
AX769_RS16835	COG4221	oxidoreductase activity
AX769_RS16845	COG3158	transport of potassium into the cell
AX769_RS16860	COG0477	Major facilitator Superfamily
AX769_RS16875	COG1136	(ABC) transporter
AX769_RS16915	COG0667	Aldo Keto reductase
AX769_RS16925	COG3537	Alpha-1,2-mannosidase
AX769_RS16990	COG2378	regulation of single-species biofilm formation
AX769_RS17000	COG0791	NLP P60 protein
AX769_RS17010	COG0667	Aldo Keto reductase
AX769_RS17040	COG2723	6-phospho-beta-galactosidase activity
AX769_RS17045	COG0667	Aldo Keto reductase
AX769_RS17065	COG0823	Involved in the tonB-independent uptake of proteins
AX769_RS17070	COG2860	membrane
AX769_RS17110	COG1309	transcriptional regulator
AX769_RS17115	COG1309	transcriptional regulator
AX769_RS17125	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AX769_RS17140	COG0583	DNA-binding transcription factor activity
AX769_RS17155	COG2826	transposase and inactivated derivatives, IS30 family
AX769_RS17160	COG3328	transposase activity
AX769_RS17240	COG2826	transposase and inactivated derivatives, IS30 family
AX769_RS17295	COG0395	ABC-type sugar transport system, permease component
AX769_RS17300	COG1175	transmembrane transport
AX769_RS17320	COG2188	Transcriptional regulator
AX769_RS17325	COG0747	negative chemotaxis
AX769_RS17340	COG2376	Dihydroxyacetone kinase
AX769_RS17345	COG0698	ribose 5-phosphate isomerase
AX769_RS17365	COG0667	Aldo Keto reductase
AX769_RS17375	COG1846	Transcriptional regulator
AX769_RS17385	COG3340	Belongs to the peptidase S51 family
AX769_RS17390	COG2186	Transcriptional regulator
AX769_RS17395	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS17400	COG0179	Fumarylacetoacetate (FAA) hydrolase
AX769_RS17435	COG0395	ABC-type sugar transport system, permease component
AX769_RS17440	COG2084	Dehydrogenase
AX769_RS17465	COG1609	Transcriptional regulator
AX769_RS17470	COG0656	L-ascorbic acid biosynthetic process
AX769_RS17480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AX769_RS17490	COG1609	Transcriptional regulator
AX769_RS17515	COG4948	Mandelate Racemase Muconate Lactonizing
AX769_RS17535	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS17565	COG0395	ABC-type sugar transport system, permease component
AX769_RS17570	COG1175	transmembrane transport
AX769_RS17580	COG0673	inositol 2-dehydrogenase activity
AX769_RS17585	COG1349	DNA-binding transcription factor activity
AX769_RS17590	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AX769_RS17600	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AX769_RS17605	COG1105	Belongs to the carbohydrate kinase PfkB family
AX769_RS17625	COG0346	lactoylglutathione lyase activity
AX769_RS17660	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AX769_RS17700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AX769_RS17705	COG1402	creatininase
AX769_RS17715	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AX769_RS17745	COG2362	D-Aminopeptidase
AX769_RS17750	COG4608	Belongs to the ABC transporter superfamily
AX769_RS17755	COG0444	Belongs to the ABC transporter superfamily
AX769_RS17760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AX769_RS17780	COG0456	acetyltransferase
AX769_RS17785	COG1316	TRANSCRIPTIONal
AX769_RS17790	COG0745	RESPONSE REGULATOR receiver
AX769_RS17800	COG2205	protein histidine kinase activity
AX769_RS17805	COG4221	oxidoreductase activity
AX769_RS17815	COG2188	Transcriptional regulator
AX769_RS17820	COG1131	(ABC) transporter
AX769_RS17825	COG0366	Alpha amylase catalytic
AX769_RS17845	COG1609	Transcriptional regulator
AX769_RS17925	COG0653	protein targeting
AX769_RS17930	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AX769_RS17935	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AX769_RS17940	COG5401	PFAM Sporulation and spore germination
AX769_RS17945	COG5002	protein histidine kinase activity
AX769_RS17950	COG0745	RESPONSE REGULATOR receiver
AX769_RS17960	COG1937	Protein conserved in bacteria
AX769_RS17965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AX769_RS18000	COG4977	sequence-specific DNA binding
AX769_RS18005	COG1482	cell wall glycoprotein biosynthetic process
AX769_RS18060	COG0463	Glycosyl transferase, family 2
AX769_RS18120	COG0438	transferase activity, transferring glycosyl groups
AX769_RS18135	COG0686	Belongs to the AlaDH PNT family
AX769_RS18155	COG1335	isochorismatase
AX769_RS18160	COG4989	oxidoreductase activity
AX769_RS18185	COG1879	ABC-type sugar transport system periplasmic component
AX769_RS18190	COG1172	Belongs to the binding-protein-dependent transport system permease family
AX769_RS18200	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AX769_RS18220	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AX769_RS18245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AX769_RS18250	COG0424	maF-like protein
AX769_RS18255	COG4770	biotin carboxylase activity
AX769_RS18275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AX769_RS18290	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AX769_RS18305	COG1079	Belongs to the binding-protein-dependent transport system permease family
AX769_RS18310	COG4603	Belongs to the binding-protein-dependent transport system permease family
AX769_RS18315	COG3845	ABC transporter
AX769_RS18320	COG1744	ABC transporter substrate-binding protein PnrA-like
AX769_RS18335	COG2009	succinate dehydrogenase
AX769_RS18350	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AX769_RS18375	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AX769_RS18385	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AX769_RS18400	COG0708	Exodeoxyribonuclease III
AX769_RS18405	COG0180	Tryptophanyl-tRNA synthetase
AX769_RS18425	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AX769_RS18425	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AX769_RS18430	COG0477	Major facilitator Superfamily
AX769_RS18435	COG1132	(ABC) transporter
AX769_RS18440	COG1335	isochorismatase
AX769_RS18460	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AX769_RS18490	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AX769_RS18495	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AX769_RS18495	COG1754	DNA topoisomerase type I activity
AX769_RS18525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AX769_RS18535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AX769_RS18560	COG1435	thymidine kinase activity
AX769_RS18580	COG0579	oxidoreductase
AX769_RS18595	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AX769_RS18620	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AX769_RS18645	COG0433	COG0433 Predicted ATPase
AX769_RS18675	COG3264	Mechanosensitive ion channel
AX769_RS18675	COG1511	domain protein
AX769_RS18685	COG1132	(ABC) transporter
AX769_RS18690	COG2197	response regulator
AX769_RS18700	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AX769_RS18705	COG2205	protein histidine kinase activity
AX769_RS18710	COG0745	RESPONSE REGULATOR receiver
AX769_RS18720	COG1136	(ABC) transporter
AX769_RS18745	COG0395	ABC-type sugar transport system, permease component
AX769_RS18775	COG3321	synthase
AX769_RS18775	COG0604	alcohol dehydrogenase
AX769_RS18780	COG0081	regulation of translation
AX769_RS18785	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AX769_RS18810	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AX769_RS18820	COG2030	dehydratase
AX769_RS18840	COG3424	synthase
AX769_RS18850	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AX769_RS18865	COG1960	acyl-CoA dehydrogenase activity
AX769_RS18895	COG0318	PFAM AMP-dependent synthetase and ligase
AX769_RS18905	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS18910	COG1012	belongs to the aldehyde dehydrogenase family
AX769_RS18930	COG1960	acyl-CoA dehydrogenase activity
AX769_RS18940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AX769_RS18945	COG1024	Enoyl-CoA hydratase
AX769_RS18950	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS18955	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS18960	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AX769_RS18970	COG1024	Enoyl-CoA hydratase
AX769_RS18980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AX769_RS18985	COG0427	acetyl-CoA hydrolase
AX769_RS18990	COG0183	Belongs to the thiolase family
AX769_RS18995	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS19005	COG1960	acyl-CoA dehydrogenase activity
AX769_RS19010	COG2186	Transcriptional regulator
AX769_RS19020	COG1960	acyl-CoA dehydrogenase activity
AX769_RS19035	COG1024	Enoyl-CoA hydratase
AX769_RS19050	COG1960	acyl-CoA dehydrogenase activity
AX769_RS19055	COG0318	PFAM AMP-dependent synthetase and ligase
AX769_RS19090	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS19125	COG0366	Alpha amylase catalytic
AX769_RS19130	COG0739	heme binding
AX769_RS19150	COG1666	GTP binding
AX769_RS19160	COG0142	geranyltranstransferase activity
AX769_RS19165	COG2226	methyltransferase
AX769_RS19170	COG1169	isochorismate synthase
AX769_RS19175	COG2326	polyphosphate kinase activity
AX769_RS19180	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AX769_RS19210	COG4948	Mandelate Racemase Muconate Lactonizing
AX769_RS19215	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AX769_RS19225	COG0785	Cytochrome C biogenesis protein
AX769_RS19235	COG0406	alpha-ribazole phosphatase activity
AX769_RS19240	COG0017	Asparaginyl-tRNA synthetase
AX769_RS19265	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AX769_RS19270	COG0569	domain protein
AX769_RS19285	COG0590	tRNA wobble adenosine to inosine editing
AX769_RS19290	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AX769_RS19295	COG0745	RESPONSE REGULATOR receiver
AX769_RS19305	COG0415	Belongs to the DNA photolyase family
AX769_RS19310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AX769_RS19330	COG0412	Dienelactone hydrolase
AX769_RS19350	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AX769_RS19370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AX769_RS19375	COG1760	l-serine dehydratase
AX769_RS19380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AX769_RS19385	COG1902	pentaerythritol trinitrate reductase activity
AX769_RS19400	COG4608	Belongs to the ABC transporter superfamily
AX769_RS19405	COG0444	Belongs to the ABC transporter superfamily
AX769_RS19410	COG0747	negative chemotaxis
AX769_RS19425	COG1609	Transcriptional regulator
AX769_RS19445	COG0667	Aldo Keto reductase
AX769_RS19450	COG1254	Belongs to the acylphosphatase family
AX769_RS19460	COG0519	Catalyzes the synthesis of GMP from XMP
AX769_RS19470	COG4221	oxidoreductase activity
AX769_RS19505	COG3152	Membrane
AX769_RS19515	COG0745	RESPONSE REGULATOR receiver
AX769_RS19550	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AX769_RS19565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AX769_RS19570	COG2271	Major facilitator Superfamily
AX769_RS19580	COG3537	Alpha-1,2-mannosidase
AX769_RS19595	COG2267	carboxylic ester hydrolase activity
AX769_RS19615	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AX769_RS19620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AX769_RS19625	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS19635	COG1362	aminopeptidase activity
AX769_RS19655	COG0386	Belongs to the glutathione peroxidase family
AX769_RS19680	COG1064	alcohol dehydrogenase
AX769_RS19700	COG0598	Magnesium transport protein CorA
AX769_RS19740	COG0477	Major facilitator Superfamily
AX769_RS19760	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS19775	COG2188	Transcriptional regulator
AX769_RS19780	COG2873	o-acetylhomoserine
AX769_RS19800	COG2160	L-arabinose isomerase activity
AX769_RS19820	COG1609	Transcriptional regulator
AX769_RS19825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AX769_RS19830	COG1397	ADP-ribosylglycohydrolase
AX769_RS19835	COG2890	protein-(glutamine-N5) methyltransferase activity
AX769_RS19850	COG1215	transferase activity, transferring glycosyl groups
AX769_RS19860	COG0438	transferase activity, transferring glycosyl groups
AX769_RS19930	COG1329	Transcriptional regulator
AX769_RS19955	COG1131	(ABC) transporter
AX769_RS19970	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AX769_RS19985	COG1309	transcriptional regulator
AX769_RS20000	COG2197	response regulator
AX769_RS20005	COG4585	Histidine kinase
AX769_RS20030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AX769_RS20055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AX769_RS20060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AX769_RS20080	COG0438	transferase activity, transferring glycosyl groups
AX769_RS20095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AX769_RS20115	COG1349	DNA-binding transcription factor activity
AX769_RS20125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AX769_RS20125	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AX769_RS20125	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AX769_RS20130	COG1104	cysteine desulfurase activity
AX769_RS20140	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AX769_RS20145	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AX769_RS20160	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS20185	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AX769_RS20190	COG0710	3-dehydroquinate dehydratase activity
AX769_RS20215	COG0673	inositol 2-dehydrogenase activity
AX769_RS20225	COG3386	PFAM SMP-30 Gluconolaconase
AX769_RS20235	COG0789	Transcriptional regulator
AX769_RS20240	COG1607	acyl-coa hydrolase
AX769_RS20275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AX769_RS20290	COG0444	Belongs to the ABC transporter superfamily
AX769_RS20295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AX769_RS20300	COG0601	transmembrane transport
AX769_RS20305	COG0747	negative chemotaxis
AX769_RS20310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AX769_RS20385	COG1045	serine acetyltransferase
AX769_RS20420	COG1309	transcriptional regulator
AX769_RS20430	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AX769_RS20465	COG0395	ABC-type sugar transport system, permease component
AX769_RS20470	COG1175	transmembrane transport
AX769_RS20485	COG1609	Transcriptional regulator
AX769_RS20500	COG2188	Transcriptional regulator
AX769_RS20515	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AX769_RS20560	COG2957	Belongs to the agmatine deiminase family
AX769_RS20580	COG0667	Aldo Keto reductase
AX769_RS20595	COG1846	Transcriptional regulator
AX769_RS20600	COG0667	Aldo Keto reductase
AX769_RS20615	COG0702	epimerase
AX769_RS20675	COG1064	alcohol dehydrogenase
AX769_RS20760	COG0395	ABC-type sugar transport system, permease component
AX769_RS20765	COG0667	Aldo Keto reductase
AX769_RS20780	COG3250	beta-galactosidase activity
AX769_RS20825	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AX769_RS20835	COG2963	transposase activity
AX769_RS20840	COG2801	Transposase and inactivated derivatives
AX769_RS20855	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS20865	COG4804	nuclease activity
AX769_RS20920	COG2801	Transposase and inactivated derivatives
AX769_RS20945	COG2378	regulation of single-species biofilm formation
AX769_RS20970	COG3548	integral membrane protein
AX769_RS20975	COG2197	response regulator
AX769_RS20980	COG4585	Histidine kinase
AX769_RS21025	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AX769_RS21050	COG1595	DNA-templated transcription, initiation
AX769_RS21055	COG1595	DNA-templated transcription, initiation
AX769_RS21080	COG2017	converts alpha-aldose to the beta-anomer
AX769_RS21125	COG2801	Transposase and inactivated derivatives
AX769_RS21185	COG2017	converts alpha-aldose to the beta-anomer
AX769_RS21260	COG1192	Involved in chromosome partitioning
AX769_RS21275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AX769_RS21280	COG3387	PFAM Glycoside hydrolase 15-related
AX769_RS21315	COG3328	transposase activity
AX769_RS21320	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AX769_RS21330	COG0531	amino acid
AX769_RS21365	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AX769_RS21375	COG0406	alpha-ribazole phosphatase activity
AX769_RS21435	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AX769_RS21465	COG0589	response to stress
AX769_RS21475	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AX769_RS21555	COG1012	belongs to the aldehyde dehydrogenase family
AX769_RS21580	COG2826	transposase and inactivated derivatives, IS30 family
AX769_RS21590	COG2963	transposase activity
AX769_RS21600	COG2826	transposase and inactivated derivatives, IS30 family
AX769_RS21605	COG0829	nickel cation binding
AX769_RS21610	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AX769_RS21625	COG0832	Belongs to the urease beta subunit family
AX769_RS21630	COG0831	urea catabolic process
AX769_RS21635	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AX769_RS21640	COG3547	Transposase (IS116 IS110 IS902 family)
AX769_RS21645	COG2826	transposase and inactivated derivatives, IS30 family
AX769_RS21660	COG3119	arylsulfatase activity
AX769_RS21665	COG0477	Major facilitator Superfamily
AX769_RS21670	COG1609	Transcriptional regulator
AX769_RS21675	COG1609	Transcriptional regulator
AX769_RS21680	COG2801	Transposase and inactivated derivatives
AX769_RS21695	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS21750	COG1595	DNA-templated transcription, initiation
AX769_RS21755	COG1595	DNA-templated transcription, initiation
AX769_RS21790	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AX769_RS21815	COG2801	Transposase and inactivated derivatives
AX769_RS21820	COG2963	transposase activity
AX769_RS22085	COG2801	Transposase and inactivated derivatives
AX769_RS22130	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AX769_RS22135	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AX769_RS22270	COG1595	DNA-templated transcription, initiation
AX769_RS22290	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS22300	COG2801	Transposase and inactivated derivatives
AX769_RS22310	COG1070	Carbohydrate kinase
AX769_RS22315	COG1028	Short-chain dehydrogenase reductase Sdr
AX769_RS22315	COG3347	Dehydrogenase
AX769_RS22325	COG1609	Transcriptional regulator
AX769_RS22335	COG3250	beta-galactosidase activity
AX769_RS22340	COG0395	ABC-type sugar transport system, permease component
AX769_RS22345	COG1175	transmembrane transport
AX769_RS22360	COG3507	Belongs to the glycosyl hydrolase 43 family
AX769_RS22380	COG1082	Xylose isomerase domain protein TIM barrel
AX769_RS22555	COG1192	Involved in chromosome partitioning
AX769_RS22570	COG2801	Transposase and inactivated derivatives
AX769_RS22575	COG2826	transposase and inactivated derivatives, IS30 family
AX769_RS22630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AX769_RS22635	COG0004	ammonium transporteR
AX769_RS22655	COG0701	Predicted permease
AX769_RS22665	COG2066	Belongs to the glutaminase family
AX769_RS22670	COG0531	amino acid
AX769_RS22675	COG0076	glutamate decarboxylase activity
AX769_RS22685	COG0589	response to stress
AX769_RS22710	COG0732	type I restriction modification DNA specificity domain