locus-tag	class	description
LROSRS0_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LROSRS0_RS00010	COG0592	DNA-directed DNA polymerase activity
LROSRS0_RS00015	COG2501	S4 domain
LROSRS0_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LROSRS0_RS00025	COG0187	DNA topoisomerase II activity
LROSRS0_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LROSRS0_RS00035	COG0393	Putative heavy-metal-binding
LROSRS0_RS00040	COG0360	Binds together with S18 to 16S ribosomal RNA
LROSRS0_RS00045	COG0629	single-stranded DNA binding
LROSRS0_RS00050	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LROSRS0_RS00060	COG0359	binds to the 23S rRNA
LROSRS0_RS00065	COG0305	Participates in initiation and elongation during chromosome replication
LROSRS0_RS00075	COG2814	Major facilitator Superfamily
LROSRS0_RS00100	COG1028	Short-chain dehydrogenase reductase Sdr
LROSRS0_RS00125	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LROSRS0_RS00155	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LROSRS0_RS00165	COG0438	transferase activity, transferring glycosyl groups
LROSRS0_RS00195	COG1917	Cupin 2, conserved barrel domain protein
LROSRS0_RS00195	COG4977	sequence-specific DNA binding
LROSRS0_RS00225	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LROSRS0_RS00230	COG1177	transmembrane transport
LROSRS0_RS00275	COG1063	alcohol dehydrogenase
LROSRS0_RS00300	COG0477	Major facilitator Superfamily
LROSRS0_RS00305	COG1114	Component of the transport system for branched-chain amino acids
LROSRS0_RS00350	COG2814	Major facilitator Superfamily
LROSRS0_RS00370	COG4989	oxidoreductase activity
LROSRS0_RS00390	COG0419	ATPase involved in DNA repair
LROSRS0_RS00400	COG4335	DNA alkylation repair
LROSRS0_RS00405	COG2378	regulation of single-species biofilm formation
LROSRS0_RS00415	COG2226	methyltransferase
LROSRS0_RS00420	COG1695	Transcriptional regulator
LROSRS0_RS00445	COG1511	domain protein
LROSRS0_RS00465	COG2249	NAD(P)H dehydrogenase (quinone) activity
LROSRS0_RS00470	COG0540	Belongs to the ATCase OTCase family
LROSRS0_RS00480	COG0505	Belongs to the CarA family
LROSRS0_RS00485	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LROSRS0_RS00495	COG1518	maintenance of DNA repeat elements
LROSRS0_RS00515	COG0697	spore germination
LROSRS0_RS00545	COG4166	transmembrane transport
LROSRS0_RS00560	COG4555	ABC transporter
LROSRS0_RS00565	COG0028	Belongs to the TPP enzyme family
LROSRS0_RS00575	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LROSRS0_RS00575	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LROSRS0_RS00580	COG0307	riboflavin synthase, alpha
LROSRS0_RS00590	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LROSRS0_RS00595	COG0386	Belongs to the glutathione peroxidase family
LROSRS0_RS00600	COG2261	transglycosylase associated protein
LROSRS0_RS00635	COG1028	Short-chain dehydrogenase reductase Sdr
LROSRS0_RS00640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LROSRS0_RS00645	COG1609	Transcriptional regulator
LROSRS0_RS00670	COG0488	(ABC) transporter
LROSRS0_RS00700	COG0765	amino acid transport
LROSRS0_RS00705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LROSRS0_RS00710	COG1733	regulation of RNA biosynthetic process
LROSRS0_RS00715	COG0656	L-ascorbic acid biosynthetic process
LROSRS0_RS00720	COG1609	Transcriptional regulator
LROSRS0_RS00730	COG0366	Alpha amylase catalytic
LROSRS0_RS00750	COG2814	Major facilitator Superfamily
LROSRS0_RS00755	COG0004	ammonium transporteR
LROSRS0_RS00770	COG0656	L-ascorbic acid biosynthetic process
LROSRS0_RS00780	COG0477	Major facilitator Superfamily
LROSRS0_RS00785	COG0583	DNA-binding transcription factor activity
LROSRS0_RS00795	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LROSRS0_RS00805	COG0024	Methionine aminopeptidase
LROSRS0_RS00810	COG0656	L-ascorbic acid biosynthetic process
LROSRS0_RS00850	COG0039	L-malate dehydrogenase activity
LROSRS0_RS00855	COG0114	fumarate hydratase activity
LROSRS0_RS00895	COG2186	Transcriptional regulator
LROSRS0_RS00900	COG0667	Aldo Keto reductase
LROSRS0_RS00925	COG3052	prosthetic group binding
LROSRS0_RS00940	COG0583	DNA-binding transcription factor activity
LROSRS0_RS00945	COG0583	DNA-binding transcription factor activity
LROSRS0_RS00950	COG0583	DNA-binding transcription factor activity
LROSRS0_RS00960	COG0163	prenyltransferase activity
LROSRS0_RS00970	COG1668	transmembrane transport
LROSRS0_RS00975	COG4152	abc transporter atp-binding protein
LROSRS0_RS00985	COG0604	alcohol dehydrogenase
LROSRS0_RS00990	COG1028	Short-chain dehydrogenase reductase Sdr
LROSRS0_RS00995	COG0789	Transcriptional regulator
LROSRS0_RS01005	COG2814	Major facilitator Superfamily
LROSRS0_RS01020	COG1113	amino acid transport
LROSRS0_RS01030	COG3479	Phenolic acid decarboxylase
LROSRS0_RS01035	COG1695	Transcriptional regulator
LROSRS0_RS01045	COG0277	FAD linked oxidase domain protein
LROSRS0_RS01055	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LROSRS0_RS01070	COG0730	response to heat
LROSRS0_RS01075	COG0446	pyridine nucleotide-disulphide oxidoreductase
LROSRS0_RS01090	COG2205	protein histidine kinase activity
LROSRS0_RS01095	COG0745	RESPONSE REGULATOR receiver
LROSRS0_RS01100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LROSRS0_RS01105	COG1216	Glycosyl transferase, family 2
LROSRS0_RS01110	COG0738	Major facilitator superfamily
LROSRS0_RS01115	COG0583	DNA-binding transcription factor activity
LROSRS0_RS01120	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LROSRS0_RS01125	COG0738	Major facilitator superfamily
LROSRS0_RS01130	COG0710	3-dehydroquinate dehydratase activity
LROSRS0_RS01140	COG1053	succinate dehydrogenase
LROSRS0_RS01140	COG3976	FMN-binding domain protein
LROSRS0_RS01140	COG0431	NADPH-dependent FMN reductase
LROSRS0_RS01165	COG2217	Heavy metal translocating P-type atpase
LROSRS0_RS01205	COG0667	Aldo Keto reductase
LROSRS0_RS01210	COG0300	oxidoreductase activity
LROSRS0_RS01215	COG1309	transcriptional regulator
LROSRS0_RS01230	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LROSRS0_RS01240	COG1957	nucleoside hydrolase
LROSRS0_RS01245	COG0604	alcohol dehydrogenase
LROSRS0_RS01250	COG4702	Belongs to the UPF0303 family
LROSRS0_RS01255	COG0673	inositol 2-dehydrogenase activity
LROSRS0_RS01260	COG2814	Major facilitator Superfamily
LROSRS0_RS01265	COG0673	inositol 2-dehydrogenase activity
LROSRS0_RS01270	COG1082	Xylose isomerase domain protein TIM barrel
LROSRS0_RS01275	COG0673	inositol 2-dehydrogenase activity
LROSRS0_RS01280	COG0673	inositol 2-dehydrogenase activity
LROSRS0_RS01285	COG2814	Major facilitator Superfamily
LROSRS0_RS01290	COG1737	Transcriptional regulator
LROSRS0_RS01295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LROSRS0_RS01320	COG1609	Transcriptional regulator
LROSRS0_RS01325	COG1869	D-ribose catabolic process
LROSRS0_RS01335	COG1172	Belongs to the binding-protein-dependent transport system permease family
LROSRS0_RS01340	COG1879	ABC-type sugar transport system periplasmic component
LROSRS0_RS01345	COG0800	Aldolase
LROSRS0_RS01350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LROSRS0_RS01355	COG1028	Short-chain dehydrogenase reductase Sdr
LROSRS0_RS01360	COG3775	system Galactitol-specific IIC component
LROSRS0_RS01365	COG1414	Transcriptional regulator
LROSRS0_RS01370	COG3835	regulator
LROSRS0_RS01375	COG2610	gluconate transmembrane transporter activity
LROSRS0_RS01380	COG1929	Belongs to the glycerate kinase type-1 family
LROSRS0_RS01485	COG0531	amino acid
LROSRS0_RS01490	COG1757	Na H antiporter
LROSRS0_RS01495	COG4475	Protein of unknown function (DUF436)
LROSRS0_RS01565	COG2814	Major facilitator Superfamily
LROSRS0_RS01570	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LROSRS0_RS01580	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LROSRS0_RS01585	COG0537	adenosine 5'-monophosphoramidase activity
LROSRS0_RS01605	COG0583	DNA-binding transcription factor activity
LROSRS0_RS01630	COG0438	transferase activity, transferring glycosyl groups
LROSRS0_RS01645	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LROSRS0_RS01650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LROSRS0_RS01650	COG1522	sequence-specific DNA binding
LROSRS0_RS01655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LROSRS0_RS01660	COG0135	phosphoribosylanthranilate isomerase activity
LROSRS0_RS01675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LROSRS0_RS01695	COG1874	Beta-galactosidase
LROSRS0_RS01715	COG0662	Cupin 2, conserved barrel domain protein
LROSRS0_RS01715	COG2207	Transcriptional regulator
LROSRS0_RS01730	COG3940	Belongs to the glycosyl hydrolase 43 family
LROSRS0_RS01740	COG2017	converts alpha-aldose to the beta-anomer
LROSRS0_RS01765	COG2160	L-arabinose isomerase activity
LROSRS0_RS01770	COG0110	maltose O-acetyltransferase activity
LROSRS0_RS01775	COG1136	(ABC) transporter
LROSRS0_RS01780	COG0577	efflux transmembrane transporter activity
LROSRS0_RS01790	COG0667	Aldo Keto reductase
LROSRS0_RS01820	COG3152	Membrane
LROSRS0_RS01845	COG0668	transmembrane transport
LROSRS0_RS01865	COG3583	domain protein
LROSRS0_RS01865	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LROSRS0_RS01865	COG3064	Membrane
LROSRS0_RS01870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LROSRS0_RS01875	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LROSRS0_RS01885	COG3639	organic phosphonate transmembrane transporter activity
LROSRS0_RS01940	COG0095	Lipoate-protein ligase
LROSRS0_RS01955	COG1045	serine acetyltransferase
LROSRS0_RS01960	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LROSRS0_RS01965	COG1846	Transcriptional regulator
LROSRS0_RS01980	COG1194	a g-specific adenine glycosylase
LROSRS0_RS01985	COG0328	RNA-DNA hybrid ribonuclease activity
LROSRS0_RS02010	COG2226	methyltransferase
LROSRS0_RS02015	COG3275	phosphorelay sensor kinase activity
LROSRS0_RS02030	COG1346	cytolysis
LROSRS0_RS02040	COG1346	cytolysis
LROSRS0_RS02050	COG0546	phosphoglycolate phosphatase activity
LROSRS0_RS02080	COG0308	aminopeptidase N
LROSRS0_RS02100	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LROSRS0_RS02115	COG2365	Tyrosine phosphatase family
LROSRS0_RS02125	COG2910	NAD(P)H-binding
LROSRS0_RS02135	COG2814	Major facilitator Superfamily
LROSRS0_RS02145	COG0589	response to stress
LROSRS0_RS02150	COG1914	H( )-stimulated, divalent metal cation uptake system
LROSRS0_RS02165	COG0776	regulation of translation
LROSRS0_RS02190	COG0561	phosphatase activity
LROSRS0_RS02200	COG2807	transmembrane transport
LROSRS0_RS02205	COG2226	methyltransferase
LROSRS0_RS02215	COG1063	alcohol dehydrogenase
LROSRS0_RS02220	COG3759	membrane
LROSRS0_RS02230	COG0586	Pfam SNARE associated Golgi protein
LROSRS0_RS02240	COG2814	Major facilitator Superfamily
LROSRS0_RS02250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LROSRS0_RS02255	COG4619	ABC transporter
LROSRS0_RS02260	COG0390	transport system, permease component
LROSRS0_RS02290	COG0438	transferase activity, transferring glycosyl groups
LROSRS0_RS02305	COG1136	(ABC) transporter
LROSRS0_RS02305	COG0577	efflux transmembrane transporter activity
LROSRS0_RS02320	COG0095	Lipoate-protein ligase
LROSRS0_RS02335	COG0583	DNA-binding transcription factor activity
LROSRS0_RS02340	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LROSRS0_RS02350	COG0357	Ribosomal RNA small subunit methyltransferase G
LROSRS0_RS02360	COG1192	Involved in chromosome partitioning
LROSRS0_RS02365	COG1475	DNA binding
LROSRS0_RS02370	COG4481	Protein conserved in bacteria
LROSRS0_RS02375	COG0012	GTP binding
LROSRS0_RS02395	COG1511	domain protein
LROSRS0_RS02395	COG1511	domain protein
LROSRS0_RS02405	COG0582	viral genome integration into host DNA
LROSRS0_RS02430	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LROSRS0_RS02440	COG0628	permease
LROSRS0_RS02445	COG0588	phosphoglycerate mutase activity
LROSRS0_RS02460	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LROSRS0_RS02500	COG3775	system Galactitol-specific IIC component
LROSRS0_RS02505	COG3414	Phosphotransferase system galactitol-specific IIB component
LROSRS0_RS02520	COG1136	(ABC) transporter
LROSRS0_RS02530	COG1131	(ABC) transporter
LROSRS0_RS02565	COG0583	DNA-binding transcription factor activity
LROSRS0_RS02570	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LROSRS0_RS02575	COG4166	transmembrane transport
LROSRS0_RS02585	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
LROSRS0_RS02600	COG0596	Alpha beta hydrolase
LROSRS0_RS02605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LROSRS0_RS02610	COG1942	4-Oxalocrotonate Tautomerase
LROSRS0_RS02620	COG2826	transposase and inactivated derivatives, IS30 family
LROSRS0_RS02625	COG0583	DNA-binding transcription factor activity
LROSRS0_RS02640	COG0110	maltose O-acetyltransferase activity
LROSRS0_RS02645	COG4221	oxidoreductase activity
LROSRS0_RS02650	COG3549	Plasmid maintenance system killer
LROSRS0_RS02670	COG1979	alcohol dehydrogenase
LROSRS0_RS02675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LROSRS0_RS02680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LROSRS0_RS02695	COG0702	epimerase
LROSRS0_RS02700	COG1959	2 iron, 2 sulfur cluster binding
LROSRS0_RS02710	COG0110	maltose O-acetyltransferase activity
LROSRS0_RS02720	COG3041	Addiction module toxin RelE StbE family
LROSRS0_RS02730	COG2217	Heavy metal translocating P-type atpase
LROSRS0_RS02735	COG2814	Major facilitator Superfamily
LROSRS0_RS02740	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LROSRS0_RS02745	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
LROSRS0_RS02750	COG0110	maltose O-acetyltransferase activity
LROSRS0_RS02755	COG0640	Transcriptional regulator
LROSRS0_RS02760	COG3321	synthase
LROSRS0_RS02760	COG0604	alcohol dehydrogenase
LROSRS0_RS02770	COG1028	Short-chain dehydrogenase reductase Sdr
LROSRS0_RS02775	COG3613	nucleoside 2-deoxyribosyltransferase
LROSRS0_RS02780	COG1063	alcohol dehydrogenase
LROSRS0_RS02810	COG1302	Protein conserved in bacteria
LROSRS0_RS02825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LROSRS0_RS02865	COG2826	transposase and inactivated derivatives, IS30 family
LROSRS0_RS02870	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LROSRS0_RS02880	COG1902	pentaerythritol trinitrate reductase activity
LROSRS0_RS02890	COG1131	(ABC) transporter
LROSRS0_RS02900	COG1309	transcriptional regulator
LROSRS0_RS02905	COG1846	Transcriptional regulator
LROSRS0_RS02915	COG0534	Mate efflux family protein
LROSRS0_RS02925	COG1131	(ABC) transporter
LROSRS0_RS02945	COG1113	amino acid transport
LROSRS0_RS02955	COG2017	converts alpha-aldose to the beta-anomer
LROSRS0_RS02960	COG3507	Belongs to the glycosyl hydrolase 43 family
LROSRS0_RS02965	COG2211	Major facilitator Superfamily
LROSRS0_RS02990	COG0110	maltose O-acetyltransferase activity
LROSRS0_RS03020	COG2211	Major facilitator Superfamily
LROSRS0_RS03035	COG0242	peptide deformylase activity
LROSRS0_RS03055	COG2252	PERMEase
LROSRS0_RS03105	COG0105	UTP biosynthetic process
LROSRS0_RS03120	COG0446	pyridine nucleotide-disulphide oxidoreductase
LROSRS0_RS03125	COG4720	Psort location CytoplasmicMembrane, score
LROSRS0_RS03130	COG1122	ATPase activity
LROSRS0_RS03135	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LROSRS0_RS03145	COG0561	phosphatase activity
LROSRS0_RS03150	COG1609	Transcriptional regulator
LROSRS0_RS03165	COG3118	belongs to the thioredoxin family
LROSRS0_RS03175	COG1937	Protein conserved in bacteria
LROSRS0_RS03185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LROSRS0_RS03190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LROSRS0_RS03220	COG0789	Transcriptional regulator
LROSRS0_RS03235	COG4221	oxidoreductase activity
LROSRS0_RS03240	COG1335	isochorismatase
LROSRS0_RS03255	COG1132	(ABC) transporter
LROSRS0_RS03275	COG0110	maltose O-acetyltransferase activity
LROSRS0_RS03350	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LROSRS0_RS03360	COG1125	glycine betaine transport
LROSRS0_RS03360	COG0517	IMP dehydrogenase activity
LROSRS0_RS03375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LROSRS0_RS03390	COG3973	AAA domain
LROSRS0_RS03415	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LROSRS0_RS03430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LROSRS0_RS03430	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LROSRS0_RS03435	COG0084	hydrolase, TatD family'
LROSRS0_RS03440	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LROSRS0_RS03445	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LROSRS0_RS03450	COG4466	Protein conserved in bacteria
LROSRS0_RS03455	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LROSRS0_RS03465	COG0488	(ABC) transporter
LROSRS0_RS03475	COG1121	(ABC) transporter
LROSRS0_RS03485	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LROSRS0_RS03490	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LROSRS0_RS03495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LROSRS0_RS03510	COG0561	phosphatase activity
LROSRS0_RS03515	COG1078	dGTPase activity
LROSRS0_RS03520	COG0095	Lipoate-protein ligase
LROSRS0_RS03530	COG3343	RNA polymerase activity
LROSRS0_RS03535	COG0504	CTP synthase activity
LROSRS0_RS03540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LROSRS0_RS03545	COG0254	rRNA binding
LROSRS0_RS03550	COG2814	Major facilitator Superfamily
LROSRS0_RS03555	COG2814	Major facilitator Superfamily
LROSRS0_RS03560	COG3764	Sortase (surface protein transpeptidase)
LROSRS0_RS03565	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LROSRS0_RS03570	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LROSRS0_RS03580	COG0736	holo-[acyl-carrier-protein] synthase activity
LROSRS0_RS03585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LROSRS0_RS03595	COG2337	Toxic component of a toxin-antitoxin (TA) module
LROSRS0_RS03610	COG0039	L-malate dehydrogenase activity
LROSRS0_RS03615	COG0193	aminoacyl-tRNA hydrolase activity
LROSRS0_RS03620	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LROSRS0_RS03625	COG2244	polysaccharide biosynthetic process
LROSRS0_RS03630	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LROSRS0_RS03640	COG1098	S1 RNA binding domain
LROSRS0_RS03645	COG0037	tRNA processing
LROSRS0_RS03650	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LROSRS0_RS03660	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LROSRS0_RS03665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LROSRS0_RS03670	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LROSRS0_RS03700	COG3104	oligopeptide transport
LROSRS0_RS03720	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LROSRS0_RS03725	COG4946	Tricorn protease homolog
LROSRS0_RS03725	COG1506	peptidase
LROSRS0_RS03725	COG0823	Involved in the tonB-independent uptake of proteins
LROSRS0_RS03730	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LROSRS0_RS03730	COG2169	Transcriptional regulator
LROSRS0_RS03735	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LROSRS0_RS03745	COG2188	Transcriptional regulator
LROSRS0_RS03750	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LROSRS0_RS03770	COG3091	SprT-like family
LROSRS0_RS03775	COG0628	permease
LROSRS0_RS03790	COG2814	Major facilitator Superfamily
LROSRS0_RS03810	COG4221	oxidoreductase activity
LROSRS0_RS03815	COG1316	TRANSCRIPTIONal
LROSRS0_RS03820	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LROSRS0_RS03825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LROSRS0_RS03845	COG3715	PTS system
LROSRS0_RS03850	COG3716	PTS system mannose fructose sorbose family IID component
LROSRS0_RS03870	COG0588	phosphoglycerate mutase activity
LROSRS0_RS03875	COG5002	protein histidine kinase activity
LROSRS0_RS03880	COG0745	RESPONSE REGULATOR receiver
LROSRS0_RS03920	COG1959	2 iron, 2 sulfur cluster binding
LROSRS0_RS03925	COG0833	amino acid
LROSRS0_RS03930	COG1428	Deoxynucleoside kinase
LROSRS0_RS03935	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LROSRS0_RS03965	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LROSRS0_RS03980	COG0697	spore germination
LROSRS0_RS03990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LROSRS0_RS03995	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LROSRS0_RS04000	COG4463	regulation of RNA biosynthetic process
LROSRS0_RS04005	COG0542	response to heat
LROSRS0_RS04010	COG1309	transcriptional regulator
LROSRS0_RS04015	COG0085	RNA polymerase activity
LROSRS0_RS04020	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LROSRS0_RS04025	COG4716	Myosin-crossreactive antigen
LROSRS0_RS04030	COG0640	Transcriptional regulator
LROSRS0_RS04040	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LROSRS0_RS04045	COG0049	tRNA binding
LROSRS0_RS04050	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LROSRS0_RS04060	COG1335	isochorismatase
LROSRS0_RS04065	COG0051	transcription antitermination factor activity, RNA binding
LROSRS0_RS04070	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LROSRS0_RS04080	COG0089	rRNA binding
LROSRS0_RS04085	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LROSRS0_RS04090	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LROSRS0_RS04095	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LROSRS0_RS04100	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LROSRS0_RS04105	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LROSRS0_RS04110	COG0255	Belongs to the universal ribosomal protein uL29 family
LROSRS0_RS04115	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LROSRS0_RS04120	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LROSRS0_RS04125	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LROSRS0_RS04130	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LROSRS0_RS04135	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LROSRS0_RS04140	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LROSRS0_RS04145	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LROSRS0_RS04150	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LROSRS0_RS04155	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LROSRS0_RS04160	COG1841	ribosomal large subunit assembly
LROSRS0_RS04165	COG0200	Binds to the 23S rRNA
LROSRS0_RS04185	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LROSRS0_RS04190	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LROSRS0_RS04195	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LROSRS0_RS04200	COG0202	RNA polymerase activity
LROSRS0_RS04205	COG0203	ribosomal protein L17
LROSRS0_RS04215	COG1122	ATPase activity
LROSRS0_RS04230	COG0101	tRNA pseudouridine synthase activity
LROSRS0_RS04235	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LROSRS0_RS04250	COG0464	growth
LROSRS0_RS04270	COG0531	amino acid
LROSRS0_RS04275	COG0076	glutamate decarboxylase activity
LROSRS0_RS04280	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LROSRS0_RS04295	COG1136	(ABC) transporter
LROSRS0_RS04300	COG0531	amino acid
LROSRS0_RS04305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LROSRS0_RS04310	COG1271	oxidase subunit
LROSRS0_RS04315	COG1294	oxidase, subunit
LROSRS0_RS04320	COG4988	ABC transporter
LROSRS0_RS04325	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LROSRS0_RS04350	COG0142	geranyltranstransferase activity
LROSRS0_RS04360	COG1705	Flagellar rod assembly protein muramidase FlgJ
LROSRS0_RS04375	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LROSRS0_RS04380	COG4851	CamS sex pheromone cAM373 precursor
LROSRS0_RS04395	COG0154	amidase activity
LROSRS0_RS04400	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LROSRS0_RS04405	COG1597	lipid kinase activity
LROSRS0_RS04410	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LROSRS0_RS04415	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LROSRS0_RS04420	COG0646	methionine synthase
LROSRS0_RS04420	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LROSRS0_RS04430	COG1476	TRANSCRIPTIONal
LROSRS0_RS04450	COG2610	gluconate transmembrane transporter activity
LROSRS0_RS04460	COG1737	Transcriptional regulator
LROSRS0_RS04505	COG0673	inositol 2-dehydrogenase activity
LROSRS0_RS04510	COG0513	Belongs to the DEAD box helicase family
LROSRS0_RS04515	COG1942	4-Oxalocrotonate Tautomerase
LROSRS0_RS04530	COG0351	phosphomethylpyrimidine kinase
LROSRS0_RS04535	COG1846	Transcriptional regulator
LROSRS0_RS04550	COG2246	polysaccharide biosynthetic process
LROSRS0_RS04560	COG2246	polysaccharide biosynthetic process
LROSRS0_RS04565	COG0716	FMN binding
LROSRS0_RS04575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LROSRS0_RS04600	COG1215	transferase activity, transferring glycosyl groups
LROSRS0_RS04600	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LROSRS0_RS04610	COG0562	UDP-galactopyranose mutase
LROSRS0_RS04620	COG0628	permease
LROSRS0_RS04625	COG1705	Flagellar rod assembly protein muramidase FlgJ
LROSRS0_RS04645	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LROSRS0_RS04700	COG3942	CHAP domain
LROSRS0_RS04700	COG1388	LysM domain
LROSRS0_RS04705	COG0501	Belongs to the peptidase M48B family
LROSRS0_RS04710	COG1704	LemA family
LROSRS0_RS04725	COG0456	acetyltransferase
LROSRS0_RS04750	COG4842	Belongs to the WXG100 family
LROSRS0_RS04860	COG4974	Belongs to the 'phage' integrase family
LROSRS0_RS04890	COG0542	response to heat
LROSRS0_RS04900	COG0463	Glycosyl transferase, family 2
LROSRS0_RS04910	COG2826	transposase and inactivated derivatives, IS30 family
LROSRS0_RS04915	COG1368	sulfuric ester hydrolase activity
LROSRS0_RS04940	COG0438	transferase activity, transferring glycosyl groups
LROSRS0_RS04945	COG0438	transferase activity, transferring glycosyl groups
LROSRS0_RS04960	COG1368	sulfuric ester hydrolase activity
LROSRS0_RS05090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LROSRS0_RS05115	COG2818	Glycosylase
LROSRS0_RS05120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LROSRS0_RS05135	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LROSRS0_RS05140	COG0477	Major facilitator Superfamily
LROSRS0_RS05150	COG0671	phosphoesterase, PA-phosphatase related
LROSRS0_RS05155	COG0495	leucyl-tRNA aminoacylation
LROSRS0_RS05160	COG2244	polysaccharide biosynthetic process
LROSRS0_RS05165	COG1187	pseudouridine synthase activity
LROSRS0_RS05170	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LROSRS0_RS05175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LROSRS0_RS05180	COG1428	Deoxynucleoside kinase
LROSRS0_RS05185	COG1970	mechanosensitive ion channel activity
LROSRS0_RS05190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LROSRS0_RS05195	COG0561	phosphatase activity
LROSRS0_RS05210	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LROSRS0_RS05230	COG1983	PspC domain protein
LROSRS0_RS05250	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LROSRS0_RS05250	COG0302	gtp cyclohydrolase
LROSRS0_RS05255	COG0302	gtp cyclohydrolase
LROSRS0_RS05265	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LROSRS0_RS05270	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LROSRS0_RS05285	COG0534	Mate efflux family protein
LROSRS0_RS05300	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LROSRS0_RS05305	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LROSRS0_RS05310	COG1464	Belongs to the NlpA lipoprotein family
LROSRS0_RS05330	COG1113	amino acid transport
LROSRS0_RS05345	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LROSRS0_RS05350	COG1012	belongs to the aldehyde dehydrogenase family
LROSRS0_RS05380	COG0018	arginyl-trna synthetase
LROSRS0_RS05385	COG1438	arginine binding
LROSRS0_RS05390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LROSRS0_RS05400	COG0420	3'-5' exonuclease activity
LROSRS0_RS05405	COG4717	serine-type aminopeptidase activity
LROSRS0_RS05410	COG3481	metal-dependent phosphohydrolase, HD sub domain
LROSRS0_RS05415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LROSRS0_RS05425	COG0537	adenosine 5'-monophosphoramidase activity
LROSRS0_RS05430	COG1131	(ABC) transporter
LROSRS0_RS05440	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LROSRS0_RS05445	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LROSRS0_RS05445	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LROSRS0_RS05465	COG1674	ftsk spoiiie
LROSRS0_RS05470	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LROSRS0_RS05475	COG2814	Major facilitator Superfamily
LROSRS0_RS05480	COG0670	Belongs to the BI1 family
LROSRS0_RS05485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LROSRS0_RS05485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LROSRS0_RS05490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LROSRS0_RS05495	COG0237	dephospho-CoA kinase activity
LROSRS0_RS05500	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LROSRS0_RS05510	COG1484	DNA-dependent DNA replication
LROSRS0_RS05515	COG2252	PERMEase
LROSRS0_RS05520	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LROSRS0_RS05535	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LROSRS0_RS05540	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LROSRS0_RS05550	COG0517	IMP dehydrogenase activity
LROSRS0_RS05550	COG0516	GMP reductase activity
LROSRS0_RS05560	COG0789	Transcriptional regulator
LROSRS0_RS05575	COG1309	transcriptional regulator
LROSRS0_RS05605	COG0463	Glycosyl transferase, family 2
LROSRS0_RS05620	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LROSRS0_RS05625	COG0564	pseudouridine synthase activity
LROSRS0_RS05635	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LROSRS0_RS05645	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LROSRS0_RS05650	COG1713	HD superfamily hydrolase involved in NAD metabolism
LROSRS0_RS05655	COG0799	negative regulation of ribosome biogenesis
LROSRS0_RS05660	COG2226	methyltransferase
LROSRS0_RS05665	COG1323	Belongs to the UPF0348 family
LROSRS0_RS05670	COG1399	metal-binding, possibly nucleic acid-binding protein
LROSRS0_RS05675	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LROSRS0_RS05685	COG0745	RESPONSE REGULATOR receiver
LROSRS0_RS05690	COG5002	protein histidine kinase activity
LROSRS0_RS05695	COG0706	membrane insertase activity
LROSRS0_RS05700	COG1254	Belongs to the acylphosphatase family
LROSRS0_RS05705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LROSRS0_RS05715	COG1733	regulation of RNA biosynthetic process
LROSRS0_RS05720	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LROSRS0_RS05725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LROSRS0_RS05725	COG0072	phenylalanine-tRNA ligase activity
LROSRS0_RS05730	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LROSRS0_RS05735	COG0572	uridine kinase
LROSRS0_RS05740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LROSRS0_RS05750	COG4841	protein insertion into membrane
LROSRS0_RS05760	COG0768	penicillin binding
LROSRS0_RS05765	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LROSRS0_RS05770	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LROSRS0_RS05775	COG0705	Rhomboid family
LROSRS0_RS05775	COG0457	Tetratricopeptide repeat
LROSRS0_RS05785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LROSRS0_RS05795	COG0584	glycerophosphoryl diester phosphodiesterase
LROSRS0_RS05800	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LROSRS0_RS05805	COG0789	Transcriptional regulator
LROSRS0_RS05845	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LROSRS0_RS05855	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LROSRS0_RS05860	COG0006	proline dipeptidase activity
LROSRS0_RS05865	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LROSRS0_RS05870	COG1302	Protein conserved in bacteria
LROSRS0_RS05875	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LROSRS0_RS05880	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LROSRS0_RS05885	COG1570	exodeoxyribonuclease VII activity
LROSRS0_RS05890	COG1722	exodeoxyribonuclease VII activity
LROSRS0_RS05900	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LROSRS0_RS05905	COG1438	arginine binding
LROSRS0_RS05910	COG0497	DNA recombination
LROSRS0_RS05920	COG0194	GDP metabolic process
LROSRS0_RS05925	COG1758	RNA polymerase activity
LROSRS0_RS05930	COG0561	phosphatase activity
LROSRS0_RS05935	COG1881	PFAM PEBP family protein
LROSRS0_RS05940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LROSRS0_RS05945	COG1554	hydrolase, family 65, central catalytic
LROSRS0_RS05950	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LROSRS0_RS05955	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LROSRS0_RS05960	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LROSRS0_RS05960	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LROSRS0_RS05965	COG0631	protein serine/threonine phosphatase activity
LROSRS0_RS05970	COG2815	serine threonine protein kinase
LROSRS0_RS05970	COG0515	serine threonine protein kinase
LROSRS0_RS05975	COG1162	GTPase activity
LROSRS0_RS05980	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LROSRS0_RS05985	COG1564	THIamine pyrophosphokinase
LROSRS0_RS05990	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LROSRS0_RS05995	COG1302	Protein conserved in bacteria
LROSRS0_RS06000	COG1461	Dihydroxyacetone kinase
LROSRS0_RS06005	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LROSRS0_RS06010	COG0416	fatty acid biosynthetic process
LROSRS0_RS06015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LROSRS0_RS06020	COG0571	ribonuclease III activity
LROSRS0_RS06025	COG1196	nuclear chromosome segregation
LROSRS0_RS06030	COG0552	protein localization to endoplasmic reticulum
LROSRS0_RS06045	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LROSRS0_RS06050	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LROSRS0_RS06065	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LROSRS0_RS06075	COG1278	Cold shock
LROSRS0_RS06095	COG0228	four-way junction DNA binding
LROSRS0_RS06100	COG1837	Belongs to the UPF0109 family
LROSRS0_RS06110	COG0336	Belongs to the RNA methyltransferase TrmD family
LROSRS0_RS06115	COG0335	large ribosomal subunit rRNA binding
LROSRS0_RS06120	COG0531	amino acid
LROSRS0_RS06130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LROSRS0_RS06135	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LROSRS0_RS06140	COG0697	spore germination
LROSRS0_RS06150	COG0561	phosphatase activity
LROSRS0_RS06155	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LROSRS0_RS06155	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LROSRS0_RS06160	COG1304	FMN binding
LROSRS0_RS06180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LROSRS0_RS06180	COG1199	ATP-dependent helicase activity
LROSRS0_RS06190	COG0017	Asparaginyl-tRNA synthetase
LROSRS0_RS06205	COG3331	DNA recombination
LROSRS0_RS06210	COG4474	Belongs to the UPF0398 family
LROSRS0_RS06215	COG3599	regulation of cell shape
LROSRS0_RS06225	COG0116	Belongs to the methyltransferase superfamily
LROSRS0_RS06245	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LROSRS0_RS06250	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LROSRS0_RS06255	COG0564	pseudouridine synthase activity
LROSRS0_RS06260	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LROSRS0_RS06265	COG0505	Belongs to the CarA family
LROSRS0_RS06270	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LROSRS0_RS06275	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LROSRS0_RS06285	COG1307	EDD domain protein, DegV family
LROSRS0_RS06310	COG0656	L-ascorbic acid biosynthetic process
LROSRS0_RS06315	COG0519	Catalyzes the synthesis of GMP from XMP
LROSRS0_RS06325	COG0656	L-ascorbic acid biosynthetic process
LROSRS0_RS06335	COG0589	response to stress
LROSRS0_RS06380	COG1472	Belongs to the glycosyl hydrolase 3 family
LROSRS0_RS06385	COG2197	response regulator
LROSRS0_RS06390	COG4585	Histidine kinase
LROSRS0_RS06400	COG1131	(ABC) transporter
LROSRS0_RS06410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LROSRS0_RS06415	COG4166	transmembrane transport
LROSRS0_RS06430	COG0352	thiamine-phosphate diphosphorylase activity
LROSRS0_RS06435	COG0351	phosphomethylpyrimidine kinase
LROSRS0_RS06440	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LROSRS0_RS06450	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LROSRS0_RS06465	COG1227	inorganic diphosphatase activity
LROSRS0_RS06470	COG0583	DNA-binding transcription factor activity
LROSRS0_RS06480	COG0187	DNA topoisomerase II activity
LROSRS0_RS06485	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LROSRS0_RS06495	COG4974	Belongs to the 'phage' integrase family
LROSRS0_RS06500	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LROSRS0_RS06505	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LROSRS0_RS06510	COG0758	DNA mediated transformation
LROSRS0_RS06515	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LROSRS0_RS06530	COG1070	Carbohydrate kinase
LROSRS0_RS06540	COG0738	Major facilitator superfamily
LROSRS0_RS06600	COG1396	sequence-specific DNA binding
LROSRS0_RS06605	COG4479	Belongs to the UPF0346 family
LROSRS0_RS06610	COG4698	Protein conserved in bacteria
LROSRS0_RS06615	COG2755	lipolytic protein G-D-S-L family
LROSRS0_RS06620	COG1307	EDD domain protein, DegV family
LROSRS0_RS06625	COG1272	protein, Hemolysin III
LROSRS0_RS06630	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LROSRS0_RS06635	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LROSRS0_RS06640	COG0488	(ABC) transporter
LROSRS0_RS06645	COG0617	tRNA 3'-terminal CCA addition
LROSRS0_RS06650	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LROSRS0_RS06660	COG0457	Tetratricopeptide repeat
LROSRS0_RS06670	COG1160	GTP binding
LROSRS0_RS06675	COG0539	negative regulation of cytoplasmic translation
LROSRS0_RS06680	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LROSRS0_RS06690	COG0514	ATP-dependent DNA helicase (RecQ)
LROSRS0_RS06700	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LROSRS0_RS06705	COG1187	pseudouridine synthase activity
LROSRS0_RS06710	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LROSRS0_RS06715	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LROSRS0_RS06730	COG2996	Protein conserved in bacteria
LROSRS0_RS06740	COG0587	DNA-directed DNA polymerase activity
LROSRS0_RS06760	COG2384	SAM-dependent methyltransferase
LROSRS0_RS06765	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LROSRS0_RS06770	COG0358	DNA primase activity
LROSRS0_RS06780	COG0751	glycine-tRNA ligase activity
LROSRS0_RS06785	COG0752	glycyl-tRNA synthetase alpha subunit
LROSRS0_RS06790	COG1381	Involved in DNA repair and RecF pathway recombination
LROSRS0_RS06795	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LROSRS0_RS06800	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LROSRS0_RS06805	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LROSRS0_RS06810	COG1702	phosphate starvation-inducible protein PhoH
LROSRS0_RS06815	COG1610	YqeY-like protein
LROSRS0_RS06820	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LROSRS0_RS06825	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LROSRS0_RS06830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LROSRS0_RS06840	COG0431	NADPH-dependent FMN reductase
LROSRS0_RS06840	COG1053	succinate dehydrogenase
LROSRS0_RS06840	COG3976	FMN-binding domain protein
LROSRS0_RS06850	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LROSRS0_RS06855	COG0124	histidyl-tRNA synthetase
LROSRS0_RS06860	COG0860	N-Acetylmuramoyl-L-alanine amidase
LROSRS0_RS06865	COG3001	Fructosamine kinase
LROSRS0_RS06870	COG1490	D-aminoacyl-tRNA deacylase activity
LROSRS0_RS06875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LROSRS0_RS06885	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LROSRS0_RS06890	COG2264	protein methyltransferase activity
LROSRS0_RS06895	COG0604	alcohol dehydrogenase
LROSRS0_RS06905	COG0481	GTPase activity
LROSRS0_RS06910	COG0484	heat shock protein binding
LROSRS0_RS06915	COG0443	Heat shock 70 kDa protein
LROSRS0_RS06920	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LROSRS0_RS06925	COG1420	regulation of RNA biosynthetic process
LROSRS0_RS06930	COG0196	riboflavin kinase activity
LROSRS0_RS06935	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LROSRS0_RS06940	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LROSRS0_RS06945	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LROSRS0_RS06945	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LROSRS0_RS06955	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LROSRS0_RS06960	COG0195	Participates in both transcription termination and antitermination
LROSRS0_RS06970	COG0346	lactoylglutathione lyase activity
LROSRS0_RS06975	COG2176	DNA-directed DNA polymerase activity
LROSRS0_RS06980	COG0442	prolyl-tRNA aminoacylation
LROSRS0_RS06985	COG0750	zinc metalloprotease
LROSRS0_RS06990	COG4589	Belongs to the CDS family
LROSRS0_RS06995	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LROSRS0_RS07005	COG0528	UMP kinase activity
LROSRS0_RS07010	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LROSRS0_RS07020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LROSRS0_RS07025	COG2827	Endonuclease containing a URI domain
LROSRS0_RS07030	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LROSRS0_RS07035	COG0204	Acyl-transferase
LROSRS0_RS07040	COG1132	(ABC) transporter
LROSRS0_RS07045	COG1132	(ABC) transporter
LROSRS0_RS07050	COG3763	UPF0154 protein
LROSRS0_RS07055	COG4224	UPF0291 protein
LROSRS0_RS07060	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LROSRS0_RS07075	COG3425	synthase
LROSRS0_RS07085	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LROSRS0_RS07100	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LROSRS0_RS07100	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LROSRS0_RS07105	COG5416	Lipopolysaccharide assembly protein A domain
LROSRS0_RS07110	COG0300	oxidoreductase activity
LROSRS0_RS07115	COG1234	tRNA 3'-trailer cleavage
LROSRS0_RS07125	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LROSRS0_RS07125	COG2755	lipolytic protein G-D-S-L family
LROSRS0_RS07130	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LROSRS0_RS07135	COG0322	excinuclease ABC activity
LROSRS0_RS07140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LROSRS0_RS07145	COG1126	abc transporter atp-binding protein
LROSRS0_RS07150	COG0765	amino acid transport
LROSRS0_RS07165	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LROSRS0_RS07170	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LROSRS0_RS07175	COG0544	peptidyl-prolyl cis-trans isomerase activity
LROSRS0_RS07180	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LROSRS0_RS07195	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LROSRS0_RS07200	COG0268	Binds directly to 16S ribosomal RNA
LROSRS0_RS07205	COG1466	dna polymerase III delta subunit
LROSRS0_RS07210	COG2333	competence protein COMEC
LROSRS0_RS07210	COG0658	competence protein
LROSRS0_RS07215	COG2131	deaminase
LROSRS0_RS07220	COG1596	polysaccharide export
LROSRS0_RS07220	COG1555	photosystem II stabilization
LROSRS0_RS07225	COG3480	Lon protease (S16) C-terminal proteolytic domain
LROSRS0_RS07230	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LROSRS0_RS07235	COG0742	ribosomal rna small subunit methyltransferase
LROSRS0_RS07240	COG4471	UPF0298 protein
LROSRS0_RS07245	COG0772	Belongs to the SEDS family
LROSRS0_RS07250	COG1217	gtp-binding protein TYPA
LROSRS0_RS07255	COG0483	inositol monophosphate 1-phosphatase activity
LROSRS0_RS07260	COG4476	Belongs to the UPF0223 family
LROSRS0_RS07290	COG0242	peptide deformylase activity
LROSRS0_RS07305	COG5503	Protein of unknown function (DUF1447)
LROSRS0_RS07310	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LROSRS0_RS07315	COG1597	lipid kinase activity
LROSRS0_RS07330	COG0791	NLP P60 protein
LROSRS0_RS07335	COG1028	Short-chain dehydrogenase reductase Sdr
LROSRS0_RS07355	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LROSRS0_RS07380	COG2267	carboxylic ester hydrolase activity
LROSRS0_RS07385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LROSRS0_RS07390	COG3290	protein histidine kinase activity
LROSRS0_RS07395	COG4565	transcriptional regulatory protein
LROSRS0_RS07400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LROSRS0_RS07410	COG4720	Psort location CytoplasmicMembrane, score
LROSRS0_RS07415	COG4475	Protein of unknown function (DUF436)
LROSRS0_RS07435	COG0124	histidyl-tRNA synthetase
LROSRS0_RS07440	COG4720	Psort location CytoplasmicMembrane, score
LROSRS0_RS07445	COG4475	Protein of unknown function (DUF436)
LROSRS0_RS07460	COG0351	phosphomethylpyrimidine kinase
LROSRS0_RS07465	COG0531	amino acid
LROSRS0_RS07475	COG1609	Transcriptional regulator
LROSRS0_RS07560	COG2957	Belongs to the agmatine deiminase family
LROSRS0_RS07565	COG0531	amino acid
LROSRS0_RS07570	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LROSRS0_RS07575	COG0235	Class ii aldolase
LROSRS0_RS07580	COG2826	transposase and inactivated derivatives, IS30 family
LROSRS0_RS07585	COG3623	hexulose-6-phosphate isomerase
LROSRS0_RS07590	COG1070	Carbohydrate kinase
LROSRS0_RS07600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LROSRS0_RS07610	COG3775	system Galactitol-specific IIC component
LROSRS0_RS07635	COG1609	Transcriptional regulator
LROSRS0_RS07645	COG0018	arginyl-trna synthetase
LROSRS0_RS07650	COG0833	amino acid
LROSRS0_RS07655	COG1438	arginine binding
LROSRS0_RS07670	COG0436	Aminotransferase
LROSRS0_RS07680	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LROSRS0_RS07685	COG2235	arginine
LROSRS0_RS07695	COG1288	antiporter activity
LROSRS0_RS07705	COG3192	ethanolamine utilization protein
LROSRS0_RS07720	COG4302	ethanolamine ammonia-lyase activity
LROSRS0_RS07725	COG4303	Ethanolamine ammonia lyase large subunit
LROSRS0_RS07745	COG1454	alcohol dehydrogenase
LROSRS0_RS07745	COG1012	belongs to the aldehyde dehydrogenase family
LROSRS0_RS07770	COG0483	inositol monophosphate 1-phosphatase activity
LROSRS0_RS07790	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LROSRS0_RS07795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LROSRS0_RS07805	COG1012	belongs to the aldehyde dehydrogenase family
LROSRS0_RS07820	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
LROSRS0_RS07830	COG0849	cell division
LROSRS0_RS07835	COG4869	propanediol catabolic process
LROSRS0_RS07895	COG1053	succinate dehydrogenase
LROSRS0_RS07895	COG0431	NADPH-dependent FMN reductase
LROSRS0_RS07895	COG3976	FMN-binding domain protein
LROSRS0_RS07910	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LROSRS0_RS07915	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
LROSRS0_RS07925	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LROSRS0_RS07935	COG0181	hydroxymethylbilane synthase activity
LROSRS0_RS07940	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LROSRS0_RS07945	COG1648	precorrin-2 dehydrogenase activity
LROSRS0_RS07945	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LROSRS0_RS07950	COG1492	cobalamin metabolic process
LROSRS0_RS07955	COG1122	ATPase activity
LROSRS0_RS07970	COG0310	cobalt ion transport
LROSRS0_RS07985	COG1587	Uroporphyrinogen-III synthase
LROSRS0_RS07985	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LROSRS0_RS08020	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
LROSRS0_RS08035	COG1797	cobyrinic acid a,c-diamide synthase activity
LROSRS0_RS08040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LROSRS0_RS08050	COG2096	Adenosyltransferase
LROSRS0_RS08055	COG0406	alpha-ribazole phosphatase activity
LROSRS0_RS08060	COG0716	FMN binding
LROSRS0_RS08080	COG0738	Major facilitator superfamily
LROSRS0_RS08085	COG1869	D-ribose catabolic process
LROSRS0_RS08095	COG1053	succinate dehydrogenase
LROSRS0_RS08100	COG0583	DNA-binding transcription factor activity
LROSRS0_RS08115	COG1609	Transcriptional regulator
LROSRS0_RS08150	COG2390	Transcriptional regulator
LROSRS0_RS08155	COG0813	purine-nucleoside phosphorylase activity
LROSRS0_RS08160	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LROSRS0_RS08165	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LROSRS0_RS08175	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LROSRS0_RS08185	COG0561	phosphatase activity
LROSRS0_RS08190	COG3527	Alpha-acetolactate decarboxylase
LROSRS0_RS08195	COG0028	Belongs to the TPP enzyme family
LROSRS0_RS08200	COG0402	S-adenosylhomocysteine deaminase activity
LROSRS0_RS08205	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LROSRS0_RS08230	COG2011	ABC-type metal ion transport system permease component
LROSRS0_RS08235	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LROSRS0_RS08245	COG0667	Aldo Keto reductase
LROSRS0_RS08250	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LROSRS0_RS08260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LROSRS0_RS08270	COG0406	alpha-ribazole phosphatase activity
LROSRS0_RS08275	COG0482	sulfurtransferase activity
LROSRS0_RS08285	COG1104	cysteine desulfurase activity
LROSRS0_RS08290	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LROSRS0_RS08300	COG0494	nUDIX hydrolase
LROSRS0_RS08305	COG1278	Cold shock
LROSRS0_RS08320	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LROSRS0_RS08325	COG3599	regulation of cell shape
LROSRS0_RS08335	COG0762	integral membrane protein
LROSRS0_RS08340	COG1799	cell septum assembly
LROSRS0_RS08355	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LROSRS0_RS08360	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LROSRS0_RS08365	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LROSRS0_RS08370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LROSRS0_RS08375	COG0768	penicillin binding
LROSRS0_RS08385	COG0275	rRNA processing
LROSRS0_RS08390	COG2001	Belongs to the MraZ family
LROSRS0_RS08410	COG1674	ftsk spoiiie
LROSRS0_RS08415	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LROSRS0_RS08425	COG0628	permease
LROSRS0_RS08430	COG2706	6-phosphogluconolactonase activity
LROSRS0_RS08435	COG3142	Participates in the control of copper homeostasis
LROSRS0_RS08440	COG0564	pseudouridine synthase activity
LROSRS0_RS08445	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LROSRS0_RS08450	COG2357	RelA SpoT domain protein
LROSRS0_RS08460	COG1164	Oligoendopeptidase f
LROSRS0_RS08495	COG4862	establishment of competence for transformation
LROSRS0_RS08500	COG1393	Belongs to the ArsC family
LROSRS0_RS08505	COG1234	tRNA 3'-trailer cleavage
LROSRS0_RS08635	COG0539	negative regulation of cytoplasmic translation
LROSRS0_RS08645	COG0586	Pfam SNARE associated Golgi protein
LROSRS0_RS08655	COG0647	UMP catabolic process
LROSRS0_RS08660	COG4470	Protein conserved in bacteria
LROSRS0_RS08670	COG1113	amino acid transport
LROSRS0_RS08675	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LROSRS0_RS08680	COG0827	DNA restriction-modification system
LROSRS0_RS08705	COG4537	Required for transformation and DNA binding
LROSRS0_RS08715	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LROSRS0_RS08720	COG0217	transcriptional regulatory protein
LROSRS0_RS08735	COG1609	Transcriptional regulator
LROSRS0_RS08740	COG0006	proline dipeptidase activity
LROSRS0_RS08760	COG0667	Aldo Keto reductase
LROSRS0_RS08770	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LROSRS0_RS08780	COG1719	4-vinyl reductase, 4VR
LROSRS0_RS08785	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LROSRS0_RS08790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LROSRS0_RS08795	COG1696	Membrane protein involved in D-alanine export
LROSRS0_RS08800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LROSRS0_RS08810	COG3118	belongs to the thioredoxin family
LROSRS0_RS08815	COG1193	negative regulation of DNA recombination
LROSRS0_RS08825	COG3906	Belongs to the UPF0473 family
LROSRS0_RS08830	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LROSRS0_RS08835	COG4472	Bacterial protein of unknown function (DUF965)
LROSRS0_RS08840	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LROSRS0_RS08845	COG0513	Belongs to the DEAD box helicase family
LROSRS0_RS08850	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LROSRS0_RS08855	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LROSRS0_RS08860	COG1862	Preprotein translocase
LROSRS0_RS08865	COG2255	four-way junction helicase activity
LROSRS0_RS08870	COG0632	four-way junction helicase activity
LROSRS0_RS08875	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LROSRS0_RS08880	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LROSRS0_RS08885	COG1418	mRNA catabolic process
LROSRS0_RS08895	COG1131	(ABC) transporter
LROSRS0_RS08910	COG1136	(ABC) transporter
LROSRS0_RS08915	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LROSRS0_RS08920	COG1546	Belongs to the CinA family
LROSRS0_RS08920	COG1058	Belongs to the CinA family
LROSRS0_RS08925	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LROSRS0_RS08930	COG1426	Protein conserved in bacteria
LROSRS0_RS08935	COG0612	Peptidase, M16
LROSRS0_RS08940	COG0612	Peptidase, M16
LROSRS0_RS08945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LROSRS0_RS08950	COG1126	abc transporter atp-binding protein
LROSRS0_RS08955	COG0765	amino acid transport
LROSRS0_RS08970	COG1077	Cell shape determining protein MreB Mrl
LROSRS0_RS08975	COG2003	Belongs to the UPF0758 family
LROSRS0_RS08980	COG0285	dihydrofolate synthase activity
LROSRS0_RS08985	COG0525	valine-tRNA ligase activity
LROSRS0_RS08990	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LROSRS0_RS09010	COG0301	tRNA thio-modification
LROSRS0_RS09015	COG1104	cysteine desulfurase activity
LROSRS0_RS09020	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LROSRS0_RS09025	COG1956	GAF domain-containing protein
LROSRS0_RS09030	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LROSRS0_RS09040	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LROSRS0_RS09070	COG1181	Belongs to the D-alanine--D-alanine ligase family
LROSRS0_RS09080	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LROSRS0_RS09085	COG0509	glycine decarboxylation via glycine cleavage system
LROSRS0_RS09090	COG0772	Belongs to the SEDS family
LROSRS0_RS09105	COG1077	Cell shape determining protein MreB Mrl
LROSRS0_RS09110	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LROSRS0_RS09120	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LROSRS0_RS09125	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LROSRS0_RS09130	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LROSRS0_RS09135	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LROSRS0_RS09140	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LROSRS0_RS09145	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LROSRS0_RS09150	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LROSRS0_RS09155	COG0356	it plays a direct role in the translocation of protons across the membrane
LROSRS0_RS09165	COG2801	Transposase and inactivated derivatives
LROSRS0_RS09170	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LROSRS0_RS09175	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LROSRS0_RS09180	COG0009	L-threonylcarbamoyladenylate synthase
LROSRS0_RS09185	COG2890	protein-(glutamine-N5) methyltransferase activity
LROSRS0_RS09190	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LROSRS0_RS09195	COG1435	thymidine kinase activity
LROSRS0_RS09200	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LROSRS0_RS09205	COG3442	glutamine amidotransferase
LROSRS0_RS09215	COG1113	amino acid transport
LROSRS0_RS09225	COG1482	cell wall glycoprotein biosynthetic process
LROSRS0_RS09230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LROSRS0_RS09235	COG1174	glycine betaine transport
LROSRS0_RS09240	COG1732	Glycine betaine
LROSRS0_RS09260	COG1609	Transcriptional regulator
LROSRS0_RS09270	COG1063	alcohol dehydrogenase
LROSRS0_RS09275	COG1940	carbohydrate kinase activity
LROSRS0_RS09285	COG0346	lactoylglutathione lyase activity
LROSRS0_RS09290	COG1968	undecaprenyl-diphosphatase activity
LROSRS0_RS09310	COG2826	transposase and inactivated derivatives, IS30 family
LROSRS0_RS09710	COG0025	NhaP-type Na H and K H
LROSRS0_RS09735	COG4975	Glucose uptake
LROSRS0_RS09740	COG1940	carbohydrate kinase activity
LROSRS0_RS09775	COG1250	3-hydroxyacyl-CoA dehydrogenase
LROSRS0_RS09790	COG0363	glucosamine-6-phosphate deaminase activity
LROSRS0_RS09795	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LROSRS0_RS09800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LROSRS0_RS09815	COG0025	NhaP-type Na H and K H
LROSRS0_RS09820	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LROSRS0_RS09825	COG0708	Exodeoxyribonuclease III
LROSRS0_RS09830	COG2176	DNA-directed DNA polymerase activity
LROSRS0_RS09840	COG0802	atpase or kinase
LROSRS0_RS09845	COG0280	phosphate acetyltransferase
LROSRS0_RS09850	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LROSRS0_RS09865	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LROSRS0_RS09870	COG0557	exoribonuclease II activity
LROSRS0_RS09880	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LROSRS0_RS09890	COG1309	transcriptional regulator
LROSRS0_RS09895	COG0148	phosphopyruvate hydratase activity
LROSRS0_RS09900	COG0149	triose-phosphate isomerase activity
LROSRS0_RS09915	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LROSRS0_RS09925	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LROSRS0_RS09930	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LROSRS0_RS09935	COG2190	(PTS) system
LROSRS0_RS09935	COG2211	Major facilitator Superfamily
LROSRS0_RS09945	COG2017	converts alpha-aldose to the beta-anomer
LROSRS0_RS09950	COG0602	queuosine metabolic process
LROSRS0_RS10040	COG0735	belongs to the Fur family
LROSRS0_RS10045	COG2814	Major facilitator Superfamily
LROSRS0_RS10060	COG2508	Transcriptional regulator
LROSRS0_RS10065	COG0778	Nitroreductase
LROSRS0_RS10085	COG1757	Na H antiporter
LROSRS0_RS10095	COG0740	serine-type endopeptidase activity
LROSRS0_RS10100	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LROSRS0_RS10105	COG1309	transcriptional regulator
LROSRS0_RS10115	COG1481	regulation of sporulation
LROSRS0_RS10120	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LROSRS0_RS10125	COG1660	Displays ATPase and GTPase activities
LROSRS0_RS10140	COG0531	amino acid
LROSRS0_RS10145	COG0531	amino acid
LROSRS0_RS10150	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LROSRS0_RS10155	COG0556	nucleotide-excision repair
LROSRS0_RS10160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LROSRS0_RS10165	COG0492	ferredoxin-NADP+ reductase activity
LROSRS0_RS10170	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LROSRS0_RS10175	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LROSRS0_RS10180	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LROSRS0_RS10185	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LROSRS0_RS10190	COG1950	PFAM Membrane protein of
LROSRS0_RS10200	COG0704	Plays a role in the regulation of phosphate uptake
LROSRS0_RS10205	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LROSRS0_RS10210	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LROSRS0_RS10215	COG0581	inorganic phosphate transmembrane transporter activity
LROSRS0_RS10220	COG0573	inorganic phosphate transmembrane transporter activity
LROSRS0_RS10230	COG5002	protein histidine kinase activity
LROSRS0_RS10235	COG0745	RESPONSE REGULATOR receiver
LROSRS0_RS10245	COG0653	protein targeting
LROSRS0_RS10255	COG1040	competence protein
LROSRS0_RS10260	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LROSRS0_RS10265	COG1739	Uncharacterized protein family UPF0029
LROSRS0_RS10270	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LROSRS0_RS10275	COG0531	amino acid
LROSRS0_RS10285	COG0459	protein refolding
LROSRS0_RS10290	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LROSRS0_RS10295	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LROSRS0_RS10300	COG0488	(ABC) transporter
LROSRS0_RS10305	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LROSRS0_RS10310	COG0456	acetyltransferase
LROSRS0_RS10320	COG1214	PFAM Peptidase M22, glycoprotease
LROSRS0_RS10325	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LROSRS0_RS10340	COG4467	Involved in initiation control of chromosome replication
LROSRS0_RS10345	COG0470	DNA polymerase III
LROSRS0_RS10350	COG3870	Protein conserved in bacteria
LROSRS0_RS10355	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LROSRS0_RS10360	COG1705	Flagellar rod assembly protein muramidase FlgJ
LROSRS0_RS10370	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LROSRS0_RS10375	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LROSRS0_RS10380	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LROSRS0_RS10395	COG2813	Specifically methylates the guanine in position
LROSRS0_RS10400	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LROSRS0_RS10405	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LROSRS0_RS10410	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LROSRS0_RS10415	COG1611	Belongs to the LOG family
LROSRS0_RS10420	COG0392	lysyltransferase activity
LROSRS0_RS10420	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LROSRS0_RS10430	COG0222	ribosome binding
LROSRS0_RS10440	COG0081	regulation of translation
LROSRS0_RS10475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LROSRS0_RS10480	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LROSRS0_RS10485	COG0215	cysteine-tRNA ligase activity
LROSRS0_RS10495	COG4956	integral membrane protein (PIN domain superfamily)
LROSRS0_RS10515	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LROSRS0_RS10550	COG1278	Cold shock
LROSRS0_RS10560	COG1230	cation diffusion facilitator family transporter
LROSRS0_RS10570	COG3250	beta-galactosidase activity
LROSRS0_RS10580	COG2814	Major facilitator Superfamily
LROSRS0_RS10610	COG1072	(Pantothenic acid kinase))
LROSRS0_RS10615	COG3973	AAA domain
LROSRS0_RS10620	COG0586	Pfam SNARE associated Golgi protein
LROSRS0_RS10625	COG0588	phosphoglycerate mutase activity
LROSRS0_RS10665	COG0657	acetylesterase activity
LROSRS0_RS10670	COG4608	Belongs to the ABC transporter superfamily
LROSRS0_RS10675	COG0444	Belongs to the ABC transporter superfamily
LROSRS0_RS10680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LROSRS0_RS10685	COG0601	transmembrane transport
LROSRS0_RS10690	COG4166	transmembrane transport
LROSRS0_RS10710	COG4166	transmembrane transport
LROSRS0_RS10715	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LROSRS0_RS10730	COG1396	sequence-specific DNA binding
LROSRS0_RS10735	COG1396	sequence-specific DNA binding
LROSRS0_RS10780	COG2826	transposase and inactivated derivatives, IS30 family
LROSRS0_RS10795	COG0601	transmembrane transport
LROSRS0_RS10800	COG4608	Belongs to the ABC transporter superfamily
LROSRS0_RS10815	COG4555	ABC transporter
LROSRS0_RS10820	COG0765	amino acid transport
LROSRS0_RS10825	COG0765	amino acid transport
LROSRS0_RS10830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LROSRS0_RS10850	COG0735	belongs to the Fur family
LROSRS0_RS10855	COG0194	GDP metabolic process
LROSRS0_RS10860	COG0531	amino acid
LROSRS0_RS10885	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LROSRS0_RS10890	COG1177	transmembrane transport
LROSRS0_RS10905	COG4166	transmembrane transport
LROSRS0_RS10910	COG2936	dipeptidyl-peptidase activity
LROSRS0_RS10935	COG1028	Short-chain dehydrogenase reductase Sdr
LROSRS0_RS10955	COG2267	carboxylic ester hydrolase activity
LROSRS0_RS10960	COG0488	(ABC) transporter
LROSRS0_RS10970	COG1114	Component of the transport system for branched-chain amino acids
LROSRS0_RS10985	COG0604	alcohol dehydrogenase
LROSRS0_RS10990	COG1733	regulation of RNA biosynthetic process
LROSRS0_RS11005	COG0514	ATP-dependent DNA helicase (RecQ)
LROSRS0_RS11025	COG3590	peptidase
LROSRS0_RS11030	COG3590	peptidase
LROSRS0_RS11035	COG0702	epimerase
LROSRS0_RS11050	COG0494	nUDIX hydrolase
LROSRS0_RS11055	COG1051	belongs to the nudix hydrolase family
LROSRS0_RS11060	COG1309	transcriptional regulator
LROSRS0_RS11065	COG0300	oxidoreductase activity
LROSRS0_RS11095	COG1846	Transcriptional regulator
LROSRS0_RS11105	COG0625	glutathione transferase activity
LROSRS0_RS11110	COG0640	Transcriptional regulator
LROSRS0_RS11130	COG0488	(ABC) transporter
LROSRS0_RS11165	COG1263	PTS System
LROSRS0_RS11165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LROSRS0_RS11165	COG2190	(PTS) system
LROSRS0_RS11170	COG2826	transposase and inactivated derivatives, IS30 family
LROSRS0_RS11175	COG1307	EDD domain protein, DegV family
LROSRS0_RS11180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LROSRS0_RS11185	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LROSRS0_RS11210	COG4120	Belongs to the binding-protein-dependent transport system permease family
LROSRS0_RS11220	COG1216	Glycosyl transferase, family 2
LROSRS0_RS11225	COG2826	transposase and inactivated derivatives, IS30 family
LROSRS0_RS11245	COG2084	Dehydrogenase
LROSRS0_RS11250	COG0537	adenosine 5'-monophosphoramidase activity
LROSRS0_RS11265	COG0789	Transcriptional regulator
LROSRS0_RS11270	COG1393	Belongs to the ArsC family
LROSRS0_RS11280	COG4221	oxidoreductase activity
LROSRS0_RS11285	COG1733	regulation of RNA biosynthetic process
LROSRS0_RS11295	COG3118	belongs to the thioredoxin family
LROSRS0_RS11300	COG1304	FMN binding
LROSRS0_RS11305	COG0861	Integral membrane protein TerC family
LROSRS0_RS11310	COG0564	pseudouridine synthase activity
LROSRS0_RS11315	COG0028	Belongs to the TPP enzyme family
LROSRS0_RS11325	COG1846	Transcriptional regulator
LROSRS0_RS11350	COG2801	Transposase and inactivated derivatives
LROSRS0_RS11360	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
LROSRS0_RS11365	COG3548	integral membrane protein
LROSRS0_RS11370	COG0789	Transcriptional regulator
LROSRS0_RS11380	COG0588	phosphoglycerate mutase activity
LROSRS0_RS11385	COG1368	sulfuric ester hydrolase activity
LROSRS0_RS11400	COG0681	Belongs to the peptidase S26 family
LROSRS0_RS11405	COG0492	ferredoxin-NADP+ reductase activity
LROSRS0_RS11445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LROSRS0_RS11455	COG2217	Heavy metal translocating P-type atpase
LROSRS0_RS11485	COG1957	nucleoside hydrolase
LROSRS0_RS11495	COG4684	Psort location CytoplasmicMembrane, score
LROSRS0_RS11505	COG1122	ATPase activity
LROSRS0_RS11570	COG1846	Transcriptional regulator
LROSRS0_RS11580	COG0346	lactoylglutathione lyase activity
LROSRS0_RS11595	COG0586	Pfam SNARE associated Golgi protein
LROSRS0_RS11615	COG0095	Lipoate-protein ligase
LROSRS0_RS11620	COG0589	response to stress
LROSRS0_RS11625	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LROSRS0_RS11630	COG0463	Glycosyl transferase, family 2
LROSRS0_RS11635	COG1307	EDD domain protein, DegV family
LROSRS0_RS11650	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LROSRS0_RS11655	COG2188	Transcriptional regulator
LROSRS0_RS11660	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LROSRS0_RS11670	COG1418	mRNA catabolic process
LROSRS0_RS11675	COG3279	Response regulator of the LytR AlgR family
LROSRS0_RS11680	COG1131	(ABC) transporter
LROSRS0_RS11700	COG2814	Major facilitator Superfamily
LROSRS0_RS11715	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LROSRS0_RS11715	COG0248	Ppx GppA phosphatase
LROSRS0_RS11720	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LROSRS0_RS11730	COG2326	polyphosphate kinase activity
LROSRS0_RS11735	COG0561	phosphatase activity
LROSRS0_RS11755	COG0778	Nitroreductase
LROSRS0_RS11755	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
LROSRS0_RS11765	COG1454	alcohol dehydrogenase
LROSRS0_RS11765	COG1012	belongs to the aldehyde dehydrogenase family
LROSRS0_RS11790	COG2137	regulation of response to DNA damage stimulus
LROSRS0_RS11805	COG0071	Belongs to the small heat shock protein (HSP20) family
LROSRS0_RS11815	COG1253	flavin adenine dinucleotide binding
LROSRS0_RS11820	COG2368	4-hydroxyphenylacetate
LROSRS0_RS11825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LROSRS0_RS11840	COG2814	Major facilitator Superfamily
LROSRS0_RS11845	COG1064	alcohol dehydrogenase
LROSRS0_RS11865	COG2801	Transposase and inactivated derivatives
LROSRS0_RS11875	COG2826	transposase and inactivated derivatives, IS30 family
LROSRS0_RS11895	COG0702	epimerase
LROSRS0_RS11900	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LROSRS0_RS11905	COG2252	PERMEase
LROSRS0_RS11910	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LROSRS0_RS11925	COG0657	acetylesterase activity
LROSRS0_RS11945	COG0577	efflux transmembrane transporter activity
LROSRS0_RS11945	COG1136	(ABC) transporter
LROSRS0_RS11955	COG1136	(ABC) transporter
LROSRS0_RS11995	COG2183	response to ionizing radiation
LROSRS0_RS12000	COG2814	Major facilitator Superfamily
LROSRS0_RS12030	COG1193	negative regulation of DNA recombination
LROSRS0_RS12050	COG0446	pyridine nucleotide-disulphide oxidoreductase
LROSRS0_RS12070	COG1033	growth of symbiont in host cell
LROSRS0_RS12070	COG2409	Drug exporters of the RND superfamily
LROSRS0_RS12075	COG1959	2 iron, 2 sulfur cluster binding
LROSRS0_RS12105	COG0583	DNA-binding transcription factor activity
LROSRS0_RS12120	COG1012	belongs to the aldehyde dehydrogenase family
LROSRS0_RS12155	COG0183	Belongs to the thiolase family
LROSRS0_RS12160	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LROSRS0_RS12230	COG1307	EDD domain protein, DegV family
LROSRS0_RS12245	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LROSRS0_RS12270	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LROSRS0_RS12275	COG0436	Aminotransferase
LROSRS0_RS12280	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LROSRS0_RS12285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LROSRS0_RS12290	COG1473	amidohydrolase
LROSRS0_RS12295	COG2171	N-acyltransferase activity
LROSRS0_RS12300	COG0019	diaminopimelate decarboxylase activity
LROSRS0_RS12305	COG0527	aspartate kinase activity
LROSRS0_RS12310	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LROSRS0_RS12315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LROSRS0_RS12325	COG1132	(ABC) transporter
LROSRS0_RS12330	COG1132	(ABC) transporter
LROSRS0_RS12380	COG2801	Transposase and inactivated derivatives
LROSRS0_RS12415	COG1174	glycine betaine transport
LROSRS0_RS12420	COG0517	IMP dehydrogenase activity
LROSRS0_RS12420	COG1125	glycine betaine transport
LROSRS0_RS12425	COG0604	alcohol dehydrogenase
LROSRS0_RS12440	COG3842	ATPase activity
LROSRS0_RS12445	COG1175	transmembrane transport
LROSRS0_RS12450	COG0395	ABC-type sugar transport system, permease component
LROSRS0_RS12465	COG0737	Belongs to the 5'-nucleotidase family
LROSRS0_RS12470	COG1252	NADH dehydrogenase
LROSRS0_RS12560	COG1215	transferase activity, transferring glycosyl groups
LROSRS0_RS12580	COG0446	pyridine nucleotide-disulphide oxidoreductase
LROSRS0_RS12595	COG1132	(ABC) transporter
LROSRS0_RS12615	COG0516	GMP reductase activity
LROSRS0_RS12625	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LROSRS0_RS12635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LROSRS0_RS12680	COG0463	Glycosyl transferase, family 2
LROSRS0_RS12685	COG0586	Pfam SNARE associated Golgi protein
LROSRS0_RS12690	COG3850	Histidine kinase
LROSRS0_RS12690	COG5002	protein histidine kinase activity
LROSRS0_RS12695	COG0745	RESPONSE REGULATOR receiver
LROSRS0_RS12720	COG0789	Transcriptional regulator
LROSRS0_RS12740	COG0640	Transcriptional regulator
LROSRS0_RS12745	COG1131	(ABC) transporter
LROSRS0_RS12750	COG0842	Transport permease protein
LROSRS0_RS12760	COG2226	methyltransferase
LROSRS0_RS12765	COG0531	amino acid
LROSRS0_RS12800	COG3022	response to hydroperoxide
LROSRS0_RS12810	COG1045	serine acetyltransferase
LROSRS0_RS12855	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LROSRS0_RS12860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LROSRS0_RS12865	COG1733	regulation of RNA biosynthetic process
LROSRS0_RS12870	COG4975	Glucose uptake
LROSRS0_RS12880	COG1902	pentaerythritol trinitrate reductase activity
LROSRS0_RS12890	COG1733	regulation of RNA biosynthetic process
LROSRS0_RS12905	COG1028	Short-chain dehydrogenase reductase Sdr
LROSRS0_RS12910	COG1309	transcriptional regulator
LROSRS0_RS12915	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LROSRS0_RS12930	COG5002	protein histidine kinase activity
LROSRS0_RS12935	COG0745	RESPONSE REGULATOR receiver
LROSRS0_RS12985	COG0235	Class ii aldolase
LROSRS0_RS12990	COG3623	hexulose-6-phosphate isomerase
LROSRS0_RS13010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LROSRS0_RS13020	COG1349	DNA-binding transcription factor activity
LROSRS0_RS13055	COG2197	response regulator
LROSRS0_RS13075	COG0719	Fe-S assembly protein
LROSRS0_RS13085	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LROSRS0_RS13090	COG0719	Fe-S assembly protein
LROSRS0_RS13095	COG0396	ATPase activity
LROSRS0_RS13115	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LROSRS0_RS13115	COG0167	dihydroorotate dehydrogenase activity
LROSRS0_RS13120	COG0493	'glutamate synthase
LROSRS0_RS13125	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LROSRS0_RS13135	COG3842	ATPase activity
LROSRS0_RS13145	COG1176	ABC-type spermidine putrescine transport system, permease component I
LROSRS0_RS13150	COG0436	Aminotransferase
LROSRS0_RS13155	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LROSRS0_RS13175	COG2814	Major facilitator Superfamily
LROSRS0_RS13180	COG0284	orotidine-5'-phosphate decarboxylase activity
LROSRS0_RS13185	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LROSRS0_RS13190	COG0167	dihydroorotate dehydrogenase activity
LROSRS0_RS13200	COG1033	growth of symbiont in host cell
LROSRS0_RS13200	COG2409	Drug exporters of the RND superfamily
LROSRS0_RS13210	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LROSRS0_RS13220	COG1442	glycosyl transferase family 8
LROSRS0_RS13225	COG1442	glycosyl transferase family 8
LROSRS0_RS13235	COG0445	tRNA wobble uridine modification
LROSRS0_RS13240	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LROSRS0_RS13250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LROSRS0_RS13265	COG0706	membrane insertase activity
LROSRS0_RS13270	COG0594	ribonuclease P activity
LROSRS0_RS13275	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LROSRS0_RS13325	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LROSRS0_RS13335	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LROSRS0_RS13365	COG3942	CHAP domain
LROSRS0_RS13365	COG1388	LysM domain
LROSRS0_RS13435	COG0542	response to heat
LROSRS0_RS13580	COG1192	Involved in chromosome partitioning
LROSRS0_RS13590	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LROSRS0_RS13600	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LROSRS0_RS13685	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LROSRS0_RS13715	COG2217	Heavy metal translocating P-type atpase
LROSRS0_RS13735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LROSRS0_RS13740	COG2017	converts alpha-aldose to the beta-anomer
LROSRS0_RS13795	COG2826	transposase and inactivated derivatives, IS30 family
LROSRS0_RS13955	COG2826	transposase and inactivated derivatives, IS30 family