locus-tag	class	description
H9Q81_RS00030	COG1129	ABC transporter
H9Q81_RS00040	COG1940	carbohydrate kinase activity
H9Q81_RS00045	COG0180	Tryptophanyl-tRNA synthetase
H9Q81_RS00060	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H9Q81_RS00065	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H9Q81_RS00070	COG0484	heat shock protein binding
H9Q81_RS00085	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
H9Q81_RS00090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H9Q81_RS00095	COG0295	cytidine deaminase activity
H9Q81_RS00115	COG1940	carbohydrate kinase activity
H9Q81_RS00120	COG1482	cell wall glycoprotein biosynthetic process
H9Q81_RS00135	COG0446	pyridine nucleotide-disulphide oxidoreductase
H9Q81_RS00145	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H9Q81_RS00150	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H9Q81_RS00165	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H9Q81_RS00170	COG0534	Mate efflux family protein
H9Q81_RS00175	COG0561	phosphatase activity
H9Q81_RS00180	COG1342	Belongs to the UPF0251 family
H9Q81_RS00190	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
H9Q81_RS00195	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H9Q81_RS00215	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H9Q81_RS00220	COG0653	protein targeting
H9Q81_RS00235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9Q81_RS00240	COG1968	undecaprenyl-diphosphatase activity
H9Q81_RS00245	COG1525	nuclease
H9Q81_RS00250	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H9Q81_RS00260	COG1704	LemA family
H9Q81_RS00265	COG2188	Transcriptional regulator
H9Q81_RS00275	COG0644	oxidoreductase
H9Q81_RS00285	COG2801	Transposase and inactivated derivatives
H9Q81_RS00310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H9Q81_RS00325	COG0488	(ABC) transporter
H9Q81_RS00340	COG0477	Major facilitator Superfamily
H9Q81_RS00360	COG1620	l-lactate permease
H9Q81_RS00365	COG0277	FAD linked oxidase domain protein
H9Q81_RS00380	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H9Q81_RS00390	COG1280	lysine exporter protein (LysE YggA)
H9Q81_RS00395	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H9Q81_RS00400	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
H9Q81_RS00405	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
H9Q81_RS00415	COG1234	tRNA 3'-trailer cleavage
H9Q81_RS00425	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H9Q81_RS00430	COG0217	transcriptional regulatory protein
H9Q81_RS00435	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H9Q81_RS00440	COG1882	Formate acetyltransferase
H9Q81_RS00445	COG1592	Rubrerythrin
H9Q81_RS00450	COG1739	Uncharacterized protein family UPF0029
H9Q81_RS00455	COG1994	Peptidase M50
H9Q81_RS00460	COG0658	competence protein
H9Q81_RS00460	COG2333	competence protein COMEC
H9Q81_RS00465	COG2211	Major facilitator Superfamily
H9Q81_RS00470	COG1323	Belongs to the UPF0348 family
H9Q81_RS00475	COG0534	Mate efflux family protein
H9Q81_RS00485	COG0254	rRNA binding
H9Q81_RS00515	COG1132	(ABC) transporter
H9Q81_RS00520	COG1132	(ABC) transporter
H9Q81_RS00530	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
H9Q81_RS00540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9Q81_RS00545	COG0492	ferredoxin-NADP+ reductase activity
H9Q81_RS00550	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H9Q81_RS00555	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9Q81_RS00560	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H9Q81_RS00570	COG1137	ATPase activity
H9Q81_RS00575	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H9Q81_RS00580	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H9Q81_RS00585	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9Q81_RS00590	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9Q81_RS00595	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H9Q81_RS00600	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H9Q81_RS00620	COG0612	Peptidase, M16
H9Q81_RS00625	COG0756	dUTP diphosphatase activity
H9Q81_RS00630	COG0772	Belongs to the SEDS family
H9Q81_RS00635	COG0564	pseudouridine synthase activity
H9Q81_RS00640	COG2252	PERMEase
H9Q81_RS00645	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H9Q81_RS00660	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H9Q81_RS00665	COG0825	malonyl-CoA metabolic process
H9Q81_RS00670	COG0205	6-phosphofructokinase activity
H9Q81_RS00675	COG2926	Belongs to the UPF0265 family
H9Q81_RS00680	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H9Q81_RS00685	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
H9Q81_RS00705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H9Q81_RS00710	COG1555	photosystem II stabilization
H9Q81_RS00710	COG1596	polysaccharide export
H9Q81_RS00715	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H9Q81_RS00720	COG0084	hydrolase, TatD family'
H9Q81_RS00725	COG2226	methyltransferase
H9Q81_RS00730	COG0736	holo-[acyl-carrier-protein] synthase activity
H9Q81_RS00745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H9Q81_RS00750	COG0776	regulation of translation
H9Q81_RS00760	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H9Q81_RS00765	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H9Q81_RS00770	COG1506	peptidase
H9Q81_RS00770	COG4946	Tricorn protease homolog
H9Q81_RS00770	COG0823	Involved in the tonB-independent uptake of proteins
H9Q81_RS00780	COG1283	sodium-dependent phosphate transmembrane transporter activity
H9Q81_RS00785	COG2801	Transposase and inactivated derivatives
H9Q81_RS00800	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H9Q81_RS00805	COG1183	phosphatidylcholine synthase activity
H9Q81_RS00825	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H9Q81_RS00840	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H9Q81_RS00845	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9Q81_RS00860	COG1132	(ABC) transporter
H9Q81_RS00865	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
H9Q81_RS00870	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H9Q81_RS00875	COG2364	Membrane
H9Q81_RS00880	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H9Q81_RS00895	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H9Q81_RS00900	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H9Q81_RS00925	COG1924	4 iron, 4 sulfur cluster binding
H9Q81_RS00945	COG1564	THIamine pyrophosphokinase
H9Q81_RS00960	COG2233	PERMEase
H9Q81_RS00965	COG1164	Oligoendopeptidase f
H9Q81_RS00980	COG0488	(ABC) transporter
H9Q81_RS01005	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H9Q81_RS01020	COG4149	molybdate abc transporter
H9Q81_RS01025	COG0725	ABC transporter, periplasmic molybdate-binding protein
H9Q81_RS01030	COG1027	Aspartate ammonia-lyase
H9Q81_RS01035	COG1199	ATP-dependent helicase activity
H9Q81_RS01040	COG1480	7TM receptor with intracellular HD hydrolase
H9Q81_RS01045	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H9Q81_RS01050	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H9Q81_RS01060	COG0183	Belongs to the thiolase family
H9Q81_RS01065	COG1024	Enoyl-CoA hydratase
H9Q81_RS01070	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9Q81_RS01075	COG0592	DNA-directed DNA polymerase activity
H9Q81_RS01090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9Q81_RS01105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H9Q81_RS01110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H9Q81_RS01135	COG0850	regulation of cytokinetic process
H9Q81_RS01140	COG2894	cell division
H9Q81_RS01145	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
H9Q81_RS01155	COG0716	FMN binding
H9Q81_RS01165	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
H9Q81_RS01315	COG0740	serine-type endopeptidase activity
H9Q81_RS01475	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H9Q81_RS01475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9Q81_RS01480	COG0326	Molecular chaperone. Has ATPase activity
H9Q81_RS01490	COG0561	phosphatase activity
H9Q81_RS01500	COG0789	Transcriptional regulator
H9Q81_RS01500	COG4978	Transcriptional regulator
H9Q81_RS01505	COG2059	Chromate
H9Q81_RS01515	COG0237	dephospho-CoA kinase activity
H9Q81_RS01520	COG0826	peptidase U32
H9Q81_RS01530	COG1546	Belongs to the CinA family
H9Q81_RS01530	COG1058	Belongs to the CinA family
H9Q81_RS01540	COG1461	Dihydroxyacetone kinase
H9Q81_RS01545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9Q81_RS01545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9Q81_RS01545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q81_RS01550	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H9Q81_RS01555	COG0482	sulfurtransferase activity
H9Q81_RS01560	COG0281	malic enzyme
H9Q81_RS01570	COG2966	Psort location CytoplasmicMembrane, score
H9Q81_RS01575	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H9Q81_RS01580	COG2610	gluconate transmembrane transporter activity
H9Q81_RS01585	COG0583	DNA-binding transcription factor activity
H9Q81_RS01595	COG2030	dehydratase
H9Q81_RS01600	COG1960	acyl-CoA dehydrogenase activity
H9Q81_RS01605	COG2086	electron transfer activity
H9Q81_RS01610	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H9Q81_RS01630	COG0612	Peptidase, M16
H9Q81_RS01650	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
H9Q81_RS01660	COG0514	ATP-dependent DNA helicase (RecQ)
H9Q81_RS01665	COG2373	Large extracellular alpha-helical protein
H9Q81_RS01670	COG4953	penicillin-binding protein 1C
H9Q81_RS01675	COG4591	ABC-type transport system involved in lipoprotein release permease component
H9Q81_RS01680	COG1136	(ABC) transporter
H9Q81_RS01690	COG1752	Esterase of the alpha-beta hydrolase superfamily
H9Q81_RS01695	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H9Q81_RS01700	COG0285	dihydrofolate synthase activity
H9Q81_RS01710	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
H9Q81_RS01725	COG1799	cell septum assembly
H9Q81_RS01730	COG0730	response to heat
H9Q81_RS01735	COG0859	PFAM glycosyl transferase family 9
H9Q81_RS01740	COG2364	Membrane
H9Q81_RS01745	COG1492	cobalamin metabolic process
H9Q81_RS01755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q81_RS01760	COG1304	FMN binding
H9Q81_RS01765	COG0252	asparaginase activity
H9Q81_RS01775	COG1185	polyribonucleotide nucleotidyltransferase activity
H9Q81_RS01780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9Q81_RS01785	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H9Q81_RS01795	COG0275	rRNA processing
H9Q81_RS01805	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9Q81_RS01810	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H9Q81_RS01815	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H9Q81_RS01830	COG2249	NAD(P)H dehydrogenase (quinone) activity
H9Q81_RS01840	COG0481	GTPase activity
H9Q81_RS01850	COG0632	four-way junction helicase activity
H9Q81_RS01865	COG1757	Na H antiporter
H9Q81_RS01875	COG0826	peptidase U32
H9Q81_RS01880	COG0305	Participates in initiation and elongation during chromosome replication
H9Q81_RS01885	COG0359	binds to the 23S rRNA
H9Q81_RS01895	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H9Q81_RS01910	COG0848	biopolymer transport protein
H9Q81_RS01915	COG0811	peptide transport
H9Q81_RS01935	COG1435	thymidine kinase activity
H9Q81_RS01945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H9Q81_RS01945	COG0574	Belongs to the PEP-utilizing enzyme family
H9Q81_RS01950	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
H9Q81_RS01965	COG1115	amino acid carrier protein
H9Q81_RS01975	COG1799	cell septum assembly
H9Q81_RS01980	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H9Q81_RS01985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H9Q81_RS01990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9Q81_RS01995	COG0786	glutamate:sodium symporter activity
H9Q81_RS02000	COG0616	signal peptide processing
H9Q81_RS02005	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H9Q81_RS02020	COG2715	membrane protein required for spore maturation
H9Q81_RS02025	COG0700	Nucleoside recognition
H9Q81_RS02030	COG2027	D-alanyl-D-alanine carboxypeptidase
H9Q81_RS02035	COG1619	proteins homologs of microcin C7 resistance protein MccF
H9Q81_RS02045	COG1846	Transcriptional regulator
H9Q81_RS02050	COG0534	Mate efflux family protein
H9Q81_RS02055	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9Q81_RS02060	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H9Q81_RS02065	COG0569	domain protein
H9Q81_RS02070	COG0445	tRNA wobble uridine modification
H9Q81_RS02075	COG0357	Ribosomal RNA small subunit methyltransferase G
H9Q81_RS02085	COG0729	surface antigen
H9Q81_RS02095	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9Q81_RS02105	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H9Q81_RS02115	COG0191	fructose-bisphosphate aldolase activity
H9Q81_RS02125	COG3023	N-Acetylmuramoyl-L-alanine amidase
H9Q81_RS02130	COG1278	Cold shock
H9Q81_RS02145	COG0537	adenosine 5'-monophosphoramidase activity
H9Q81_RS02150	COG0698	ribose 5-phosphate isomerase
H9Q81_RS02155	COG1047	Peptidyl-prolyl cis-trans
H9Q81_RS02160	COG0693	protein deglycase activity
H9Q81_RS02165	COG1982	Orn Lys Arg decarboxylase major
H9Q81_RS02175	COG0668	transmembrane transport
H9Q81_RS02180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9Q81_RS02185	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H9Q81_RS02190	COG4221	oxidoreductase activity
H9Q81_RS02215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9Q81_RS02240	COG0288	reversible hydration of carbon dioxide
H9Q81_RS02250	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H9Q81_RS02255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H9Q81_RS02260	COG2885	chlorophyll binding
H9Q81_RS02305	COG0482	sulfurtransferase activity
H9Q81_RS02315	COG0006	proline dipeptidase activity
H9Q81_RS02320	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H9Q81_RS02340	COG0542	response to heat
H9Q81_RS02345	COG1053	succinate dehydrogenase
H9Q81_RS02360	COG1151	hydroxylamine reductase activity
H9Q81_RS02385	COG2080	2 iron, 2 sulfur cluster binding
H9Q81_RS02385	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H9Q81_RS02390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H9Q81_RS02395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9Q81_RS02400	COG0765	amino acid transport
H9Q81_RS02405	COG1126	abc transporter atp-binding protein
H9Q81_RS02425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H9Q81_RS02430	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H9Q81_RS02445	COG2188	Transcriptional regulator
H9Q81_RS02455	COG1115	amino acid carrier protein
H9Q81_RS02460	COG0697	spore germination
H9Q81_RS02465	COG1253	flavin adenine dinucleotide binding
H9Q81_RS02470	COG0534	Mate efflux family protein
H9Q81_RS02495	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
H9Q81_RS02515	COG2996	Protein conserved in bacteria
H9Q81_RS02520	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H9Q81_RS02535	COG0561	phosphatase activity
H9Q81_RS02540	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H9Q81_RS02540	COG0519	Catalyzes the synthesis of GMP from XMP
H9Q81_RS02550	COG1737	Transcriptional regulator
H9Q81_RS02580	COG2197	response regulator
H9Q81_RS02585	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H9Q81_RS02590	COG2223	nitrite transmembrane transporter activity
H9Q81_RS02595	COG2936	dipeptidyl-peptidase activity
H9Q81_RS02610	COG0758	DNA mediated transformation
H9Q81_RS02615	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H9Q81_RS02625	COG1078	dGTPase activity
H9Q81_RS02635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H9Q81_RS02640	COG1177	transmembrane transport
H9Q81_RS02645	COG1176	ABC-type spermidine putrescine transport system, permease component I
H9Q81_RS02650	COG3842	ATPase activity
H9Q81_RS02665	COG3608	succinylglutamate desuccinylase aspartoacylase
H9Q81_RS02665	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
H9Q81_RS02675	COG0251	oxidation-reduction process
H9Q81_RS02680	COG0708	Exodeoxyribonuclease III
H9Q81_RS02715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9Q81_RS02730	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H9Q81_RS02740	COG0017	Asparaginyl-tRNA synthetase
H9Q81_RS02745	COG4224	UPF0291 protein
H9Q81_RS02765	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H9Q81_RS02780	COG0598	Magnesium transport protein CorA
H9Q81_RS02790	COG0728	peptidoglycan biosynthetic process
H9Q81_RS02800	COG0196	riboflavin kinase activity
H9Q81_RS02810	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9Q81_RS02810	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9Q81_RS02815	COG0629	single-stranded DNA binding
H9Q81_RS02820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9Q81_RS02825	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H9Q81_RS02830	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H9Q81_RS02885	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H9Q81_RS02925	COG0582	viral genome integration into host DNA
H9Q81_RS02965	COG5564	TIM-barrel signal transduction protein
H9Q81_RS02975	COG5564	TIM-barrel signal transduction protein
H9Q81_RS03025	COG0714	Associated with various cellular activities
H9Q81_RS03055	COG5434	Belongs to the glycosyl hydrolase 28 family
H9Q81_RS03080	COG0683	leucine binding
H9Q81_RS03095	COG1363	Peptidase, m42
H9Q81_RS03120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9Q81_RS03125	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H9Q81_RS03140	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
H9Q81_RS03155	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
H9Q81_RS03165	COG2271	Major facilitator Superfamily
H9Q81_RS03175	COG1115	amino acid carrier protein
H9Q81_RS03180	COG1349	DNA-binding transcription factor activity
H9Q81_RS03215	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
H9Q81_RS03235	COG2801	Transposase and inactivated derivatives
H9Q81_RS03250	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H9Q81_RS03260	COG1187	pseudouridine synthase activity
H9Q81_RS03265	COG4974	Belongs to the 'phage' integrase family
H9Q81_RS03270	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H9Q81_RS03275	COG0363	glucosamine-6-phosphate deaminase activity
H9Q81_RS03280	COG1737	Transcriptional regulator
H9Q81_RS03285	COG1242	4 iron, 4 sulfur cluster binding
H9Q81_RS03295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9Q81_RS03305	COG0765	amino acid transport
H9Q81_RS03310	COG0436	Aminotransferase
H9Q81_RS03315	COG2099	Precorrin-6x reductase
H9Q81_RS03350	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
H9Q81_RS03360	COG1797	cobyrinic acid a,c-diamide synthase activity
H9Q81_RS03365	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H9Q81_RS03375	COG1492	cobalamin metabolic process
H9Q81_RS03390	COG0352	thiamine-phosphate diphosphorylase activity
H9Q81_RS03400	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H9Q81_RS03405	COG2022	thiamine diphosphate biosynthetic process
H9Q81_RS03435	COG0617	tRNA 3'-terminal CCA addition
H9Q81_RS03440	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H9Q81_RS03450	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H9Q81_RS03455	COG0284	orotidine-5'-phosphate decarboxylase activity
H9Q81_RS03460	COG0167	dihydroorotate dehydrogenase activity
H9Q81_RS03465	COG0543	2 iron, 2 sulfur cluster binding
H9Q81_RS03470	COG0540	Belongs to the ATCase OTCase family
H9Q81_RS03485	COG4822	anaerobic cobalamin biosynthetic process
H9Q81_RS03490	COG1301	dicarboxylic acid transport
H9Q81_RS03500	COG1473	amidohydrolase
H9Q81_RS03505	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H9Q81_RS03510	COG0019	diaminopimelate decarboxylase activity
H9Q81_RS03525	COG4771	TonB-dependent receptor
H9Q81_RS03530	COG1362	aminopeptidase activity
H9Q81_RS03585	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H9Q81_RS03590	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H9Q81_RS03595	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H9Q81_RS03600	COG3842	ATPase activity
H9Q81_RS03610	COG2217	Heavy metal translocating P-type atpase
H9Q81_RS03615	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H9Q81_RS03625	COG0475	glutathione-regulated potassium exporter activity
H9Q81_RS03630	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q81_RS03640	COG3051	citrate lyase alpha subunit
H9Q81_RS03650	COG3052	prosthetic group binding
H9Q81_RS03655	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
H9Q81_RS03660	COG0511	ligase activity, forming carbon-carbon bonds
H9Q81_RS03680	COG1802	Transcriptional regulator
H9Q81_RS03685	COG1288	antiporter activity
H9Q81_RS03695	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
H9Q81_RS03695	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
H9Q81_RS03700	COG1840	ABC-type Fe3 transport system, periplasmic component
H9Q81_RS03705	COG3842	ATPase activity
H9Q81_RS03710	COG1176	ABC-type spermidine putrescine transport system, permease component I
H9Q81_RS03715	COG0151	Belongs to the GarS family
H9Q81_RS03725	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H9Q81_RS03730	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H9Q81_RS03735	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H9Q81_RS03740	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H9Q81_RS03745	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H9Q81_RS03750	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H9Q81_RS03755	COG2759	Belongs to the formate--tetrahydrofolate ligase family
H9Q81_RS03760	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H9Q81_RS03765	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H9Q81_RS03770	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H9Q81_RS03775	COG0772	Belongs to the SEDS family
H9Q81_RS03800	COG2337	Toxic component of a toxin-antitoxin (TA) module
H9Q81_RS03805	COG2336	PFAM SpoVT AbrB
H9Q81_RS03825	COG0726	polysaccharide deacetylase
H9Q81_RS03830	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
H9Q81_RS03850	COG1293	RNA-binding protein homologous to eukaryotic snRNP
H9Q81_RS03860	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H9Q81_RS03865	COG1162	GTPase activity
H9Q81_RS03870	COG2815	serine threonine protein kinase
H9Q81_RS03870	COG0515	serine threonine protein kinase
H9Q81_RS03880	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
H9Q81_RS03885	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H9Q81_RS03895	COG1837	Belongs to the UPF0109 family
H9Q81_RS03900	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H9Q81_RS03905	COG0336	Belongs to the RNA methyltransferase TrmD family
H9Q81_RS03915	COG4752	Belongs to the RNA methyltransferase TrmD family
H9Q81_RS03925	COG0776	regulation of translation
H9Q81_RS03940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9Q81_RS03950	COG1489	DNA binding
H9Q81_RS03960	COG3872	metal-dependent enzyme
H9Q81_RS03965	COG2208	phosphoserine phosphatase activity
H9Q81_RS03975	COG0322	excinuclease ABC activity
H9Q81_RS03980	COG1660	Displays ATPase and GTPase activities
H9Q81_RS03985	COG0731	radical SAM domain protein
H9Q81_RS04000	COG0674	pyruvate-flavodoxin oxidoreductase activity
H9Q81_RS04000	COG1013	pyruvate-flavodoxin oxidoreductase activity
H9Q81_RS04000	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
H9Q81_RS04000	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H9Q81_RS04005	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H9Q81_RS04010	COG0280	phosphate acetyltransferase
H9Q81_RS04015	COG0552	protein localization to endoplasmic reticulum
H9Q81_RS04030	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H9Q81_RS04035	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
H9Q81_RS04040	COG4974	Belongs to the 'phage' integrase family
H9Q81_RS04045	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
H9Q81_RS04050	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9Q81_RS04055	COG0758	DNA mediated transformation
H9Q81_RS04065	COG1570	exodeoxyribonuclease VII activity
H9Q81_RS04070	COG0556	nucleotide-excision repair
H9Q81_RS04085	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H9Q81_RS04090	COG1774	PSP1 C-terminal conserved region
H9Q81_RS04095	COG2003	Belongs to the UPF0758 family
H9Q81_RS04100	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H9Q81_RS04110	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
H9Q81_RS04115	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
H9Q81_RS04125	COG1518	maintenance of DNA repeat elements
H9Q81_RS04150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9Q81_RS04155	COG1295	ribonuclease BN
H9Q81_RS04165	COG0501	Belongs to the peptidase M48B family
H9Q81_RS04170	COG0248	Ppx GppA phosphatase
H9Q81_RS04170	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H9Q81_RS04185	COG1921	L-seryl-tRNASec selenium transferase activity
H9Q81_RS04210	COG0531	amino acid
H9Q81_RS04215	COG0076	glutamate decarboxylase activity
H9Q81_RS04235	COG0318	PFAM AMP-dependent synthetase and ligase
H9Q81_RS04245	COG1022	Amp-dependent synthetase and ligase
H9Q81_RS04255	COG0745	RESPONSE REGULATOR receiver
H9Q81_RS04265	COG0037	tRNA processing
H9Q81_RS04275	COG1196	nuclear chromosome segregation
H9Q81_RS04280	COG1663	tetraacyldisaccharide 4'-kinase activity
H9Q81_RS04295	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H9Q81_RS04300	COG0622	Phosphoesterase
H9Q81_RS04305	COG0513	Belongs to the DEAD box helicase family
H9Q81_RS04340	COG0446	pyridine nucleotide-disulphide oxidoreductase
H9Q81_RS04345	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H9Q81_RS04355	COG0210	DNA helicase
H9Q81_RS04375	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H9Q81_RS04390	COG3842	ATPase activity
H9Q81_RS04400	COG1840	ABC-type Fe3 transport system, periplasmic component
H9Q81_RS04415	COG1053	succinate dehydrogenase
H9Q81_RS04415	COG3976	FMN-binding domain protein
H9Q81_RS04420	COG1346	cytolysis
H9Q81_RS04430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H9Q81_RS04450	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H9Q81_RS04455	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H9Q81_RS04460	COG0741	lytic transglycosylase activity
H9Q81_RS04465	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H9Q81_RS04465	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H9Q81_RS04475	COG4608	Belongs to the ABC transporter superfamily
H9Q81_RS04480	COG0444	Belongs to the ABC transporter superfamily
H9Q81_RS04485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9Q81_RS04490	COG0601	transmembrane transport
H9Q81_RS04495	COG0747	negative chemotaxis
H9Q81_RS04500	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H9Q81_RS04505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H9Q81_RS04510	COG0037	tRNA processing
H9Q81_RS04520	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H9Q81_RS04530	COG1960	acyl-CoA dehydrogenase activity
H9Q81_RS04535	COG0343	queuine tRNA-ribosyltransferase activity
H9Q81_RS04540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H9Q81_RS04545	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H9Q81_RS04560	COG4536	flavin adenine dinucleotide binding
H9Q81_RS04565	COG0511	ligase activity, forming carbon-carbon bonds
H9Q81_RS04570	COG4492	Belongs to the UPF0735 family
H9Q81_RS04575	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H9Q81_RS04580	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H9Q81_RS04585	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H9Q81_RS04590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9Q81_RS04590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9Q81_RS04590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q81_RS04595	COG1381	Involved in DNA repair and RecF pathway recombination
H9Q81_RS04610	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9Q81_RS04660	COG1494	fructose-1,6-bisphosphatase
H9Q81_RS04670	COG0242	peptide deformylase activity
H9Q81_RS04675	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H9Q81_RS04680	COG0768	penicillin binding
H9Q81_RS04690	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H9Q81_RS04690	COG1918	ferrous iron import across plasma membrane
H9Q81_RS04710	COG1328	CTP reductase activity
H9Q81_RS04710	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H9Q81_RS04720	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H9Q81_RS04725	COG4120	Belongs to the binding-protein-dependent transport system permease family
H9Q81_RS04745	COG4807	Protein conserved in bacteria
H9Q81_RS04750	COG1122	ATPase activity
H9Q81_RS04755	COG4120	Belongs to the binding-protein-dependent transport system permease family
H9Q81_RS04770	COG0426	domain, Protein
H9Q81_RS04770	COG1773	rubredoxin
H9Q81_RS04775	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
H9Q81_RS04785	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H9Q81_RS04795	COG0116	Belongs to the methyltransferase superfamily
H9Q81_RS04810	COG0688	phosphatidylethanolamine metabolic process
H9Q81_RS04820	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H9Q81_RS04825	COG1490	D-aminoacyl-tRNA deacylase activity
H9Q81_RS04830	COG0429	hydrolase of the alpha beta-hydrolase fold
H9Q81_RS04865	COG4978	Transcriptional regulator
H9Q81_RS04865	COG0789	Transcriptional regulator
H9Q81_RS04895	COG2205	protein histidine kinase activity
H9Q81_RS04900	COG0745	RESPONSE REGULATOR receiver
H9Q81_RS04905	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H9Q81_RS04910	COG0154	amidase activity
H9Q81_RS04915	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H9Q81_RS04920	COG1187	pseudouridine synthase activity
H9Q81_RS04925	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H9Q81_RS04935	COG1077	Cell shape determining protein MreB Mrl
H9Q81_RS04940	COG0424	maF-like protein
H9Q81_RS04955	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H9Q81_RS04975	COG0494	nUDIX hydrolase
H9Q81_RS04980	COG0513	Belongs to the DEAD box helicase family
H9Q81_RS04995	COG0824	Thioesterase
H9Q81_RS05000	COG1683	Conserved Protein
H9Q81_RS05005	COG3976	FMN-binding domain protein
H9Q81_RS05005	COG1053	succinate dehydrogenase
H9Q81_RS05010	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H9Q81_RS05020	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H9Q81_RS05025	COG1285	pathogenesis
H9Q81_RS05040	COG1757	Na H antiporter
H9Q81_RS05045	COG2385	sporulation resulting in formation of a cellular spore
H9Q81_RS05050	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
H9Q81_RS05085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9Q81_RS05095	COG3290	protein histidine kinase activity
H9Q81_RS05100	COG4565	transcriptional regulatory protein
H9Q81_RS05115	COG2848	UPF0210 protein
H9Q81_RS05125	COG0346	lactoylglutathione lyase activity
H9Q81_RS05130	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q81_RS05135	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H9Q81_RS05145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9Q81_RS05150	COG1120	ATPase activity
H9Q81_RS05160	COG1285	pathogenesis
H9Q81_RS05165	COG0745	RESPONSE REGULATOR receiver
H9Q81_RS05170	COG5002	protein histidine kinase activity
H9Q81_RS05175	COG4771	TonB-dependent receptor
H9Q81_RS05180	COG1285	pathogenesis
H9Q81_RS05185	COG3181	Tripartite tricarboxylate transporter family receptor
H9Q81_RS05200	COG0018	arginyl-trna synthetase
H9Q81_RS05205	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
H9Q81_RS05210	COG0124	histidyl-tRNA synthetase
H9Q81_RS05215	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H9Q81_RS05225	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
H9Q81_RS05230	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H9Q81_RS05235	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H9Q81_RS05245	COG3118	belongs to the thioredoxin family
H9Q81_RS05250	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H9Q81_RS05255	COG1214	PFAM Peptidase M22, glycoprotease
H9Q81_RS05260	COG0802	atpase or kinase
H9Q81_RS05265	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
H9Q81_RS05265	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H9Q81_RS05275	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H9Q81_RS05280	COG0785	Cytochrome C biogenesis protein
H9Q81_RS05285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9Q81_RS05295	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H9Q81_RS05300	COG1217	gtp-binding protein TYPA
H9Q81_RS05335	COG2095	MarC family integral membrane protein
H9Q81_RS05340	COG0747	negative chemotaxis
H9Q81_RS05350	COG2095	MarC family integral membrane protein
H9Q81_RS05355	COG0534	Mate efflux family protein
H9Q81_RS05360	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H9Q81_RS05365	COG0716	FMN binding
H9Q81_RS05370	COG0427	acetyl-CoA hydrolase
H9Q81_RS05380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9Q81_RS05380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9Q81_RS05385	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H9Q81_RS05395	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H9Q81_RS05400	COG2868	ribosomal protein
H9Q81_RS05405	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H9Q81_RS05410	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
H9Q81_RS05415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H9Q81_RS05420	COG0228	four-way junction DNA binding
H9Q81_RS05425	COG2183	response to ionizing radiation
H9Q81_RS05435	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H9Q81_RS05440	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H9Q81_RS05445	COG0752	glycyl-tRNA synthetase alpha subunit
H9Q81_RS05450	COG0751	glycine-tRNA ligase activity
H9Q81_RS05455	COG0302	gtp cyclohydrolase
H9Q81_RS05460	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H9Q81_RS05460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H9Q81_RS05465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H9Q81_RS05485	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
H9Q81_RS05490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9Q81_RS05505	COG0848	biopolymer transport protein
H9Q81_RS05510	COG0811	peptide transport
H9Q81_RS05525	COG1285	pathogenesis
H9Q81_RS05530	COG1115	amino acid carrier protein
H9Q81_RS05535	COG0584	glycerophosphoryl diester phosphodiesterase
H9Q81_RS05540	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
H9Q81_RS05545	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
H9Q81_RS05555	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H9Q81_RS05560	COG1519	Transferase
H9Q81_RS05560	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H9Q81_RS05565	COG1519	Transferase
H9Q81_RS05565	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H9Q81_RS05570	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H9Q81_RS05575	COG2264	protein methyltransferase activity
H9Q81_RS05580	COG1692	metallophosphoesterase
H9Q81_RS05595	COG2031	fatty acid transporter
H9Q81_RS05600	COG1115	amino acid carrier protein
H9Q81_RS05610	COG0438	transferase activity, transferring glycosyl groups
H9Q81_RS05620	COG0110	maltose O-acetyltransferase activity
H9Q81_RS05625	COG1216	Glycosyl transferase, family 2
H9Q81_RS05625	COG0463	Glycosyl transferase, family 2
H9Q81_RS05640	COG1442	glycosyl transferase family 8
H9Q81_RS05645	COG1597	lipid kinase activity
H9Q81_RS05650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H9Q81_RS05655	COG0442	prolyl-tRNA aminoacylation
H9Q81_RS05660	COG0786	glutamate:sodium symporter activity
H9Q81_RS05665	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H9Q81_RS05670	COG4868	Belongs to the UPF0371 family
H9Q81_RS05690	COG0742	ribosomal rna small subunit methyltransferase
H9Q81_RS05695	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H9Q81_RS05700	COG2890	protein-(glutamine-N5) methyltransferase activity
H9Q81_RS05705	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H9Q81_RS05720	COG1595	DNA-templated transcription, initiation
H9Q81_RS05725	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
H9Q81_RS05730	COG0739	heme binding
H9Q81_RS05735	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H9Q81_RS05740	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9Q81_RS05760	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H9Q81_RS05760	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H9Q81_RS05765	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H9Q81_RS05775	COG0655	NAD(P)H dehydrogenase (quinone) activity
H9Q81_RS05790	COG0534	Mate efflux family protein
H9Q81_RS05795	COG1418	mRNA catabolic process
H9Q81_RS05800	COG1366	Belongs to the anti-sigma-factor antagonist family
H9Q81_RS05815	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H9Q81_RS05820	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H9Q81_RS05825	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
H9Q81_RS05835	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
H9Q81_RS05840	COG1301	dicarboxylic acid transport
H9Q81_RS05845	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
H9Q81_RS05850	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H9Q81_RS05855	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H9Q81_RS05860	COG1530	ribonuclease E activity
H9Q81_RS05870	COG0571	ribonuclease III activity
H9Q81_RS05875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H9Q81_RS05880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9Q81_RS05885	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H9Q81_RS05890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9Q81_RS05895	COG0416	fatty acid biosynthetic process
H9Q81_RS05900	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H9Q81_RS05910	COG0012	GTP binding
H9Q81_RS05925	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H9Q81_RS05930	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H9Q81_RS05935	COG0793	Belongs to the peptidase S41A family
H9Q81_RS05940	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
H9Q81_RS05950	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H9Q81_RS05955	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
H9Q81_RS05960	COG1534	Rna-binding protein
H9Q81_RS05965	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H9Q81_RS05970	COG0768	penicillin binding
H9Q81_RS05985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9Q81_RS06000	COG2255	four-way junction helicase activity
H9Q81_RS06005	COG4399	Belongs to the UPF0754 family
H9Q81_RS06020	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H9Q81_RS06035	COG0583	DNA-binding transcription factor activity
H9Q81_RS06040	COG1960	acyl-CoA dehydrogenase activity
H9Q81_RS06045	COG2990	Protein conserved in bacteria
H9Q81_RS06050	COG0006	proline dipeptidase activity
H9Q81_RS06055	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H9Q81_RS06060	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H9Q81_RS06065	COG2086	electron transfer activity
H9Q81_RS06070	COG1960	acyl-CoA dehydrogenase activity
H9Q81_RS06085	COG0439	Biotin carboxylase
H9Q81_RS06090	COG1302	Protein conserved in bacteria
H9Q81_RS06105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9Q81_RS06120	COG1733	regulation of RNA biosynthetic process
H9Q81_RS06130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9Q81_RS06150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H9Q81_RS06170	COG0446	pyridine nucleotide-disulphide oxidoreductase
H9Q81_RS06175	COG1115	amino acid carrier protein
H9Q81_RS06180	COG2066	Belongs to the glutaminase family
H9Q81_RS06190	COG1496	oxidoreductase activity
H9Q81_RS06195	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
H9Q81_RS06230	COG1609	Transcriptional regulator
H9Q81_RS06235	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
H9Q81_RS06305	COG5002	protein histidine kinase activity
H9Q81_RS06310	COG0745	RESPONSE REGULATOR receiver
H9Q81_RS06320	COG0573	inorganic phosphate transmembrane transporter activity
H9Q81_RS06325	COG0581	inorganic phosphate transmembrane transporter activity
H9Q81_RS06330	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H9Q81_RS06335	COG0704	Plays a role in the regulation of phosphate uptake
H9Q81_RS06340	COG4145	pantothenate transmembrane transporter activity
H9Q81_RS06355	COG1940	carbohydrate kinase activity
H9Q81_RS06360	COG1263	PTS System
H9Q81_RS06360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q81_RS06375	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H9Q81_RS06390	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
H9Q81_RS06395	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H9Q81_RS06400	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H9Q81_RS06405	COG4206	TonB-dependent receptor
H9Q81_RS06420	COG1971	Probably functions as a manganese efflux pump
H9Q81_RS06430	COG0606	chelatase, subunit chli
H9Q81_RS06435	COG1473	amidohydrolase
H9Q81_RS06440	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9Q81_RS06465	COG3422	double-strand break repair
H9Q81_RS06470	COG1966	Carbon starvation protein
H9Q81_RS06475	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
H9Q81_RS06480	COG3275	phosphorelay sensor kinase activity
H9Q81_RS06485	COG3279	Response regulator of the LytR AlgR family
H9Q81_RS06495	COG3142	Participates in the control of copper homeostasis
H9Q81_RS06510	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9Q81_RS06515	COG1446	asparaginase
H9Q81_RS06520	COG1447	Phosphotransferase system cellobiose-specific component IIA
H9Q81_RS06535	COG1228	amidohydrolase
H9Q81_RS06540	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
H9Q81_RS06545	COG2986	histidine ammonia-lyase
H9Q81_RS06550	COG2056	Na+-H+ antiporter family
H9Q81_RS06585	COG1802	Transcriptional regulator
H9Q81_RS06605	COG0246	Mannitol dehydrogenase
H9Q81_RS06610	COG1312	Catalyzes the dehydration of D-mannonate
H9Q81_RS06620	COG0557	exoribonuclease II activity
H9Q81_RS06625	COG1713	HD superfamily hydrolase involved in NAD metabolism
H9Q81_RS06655	COG0443	Heat shock 70 kDa protein
H9Q81_RS06665	COG1420	regulation of RNA biosynthetic process
H9Q81_RS06670	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H9Q81_RS06675	COG0390	transport system, permease component
H9Q81_RS06680	COG5002	protein histidine kinase activity
H9Q81_RS06685	COG0745	RESPONSE REGULATOR receiver
H9Q81_RS06690	COG0463	Glycosyl transferase, family 2
H9Q81_RS06710	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H9Q81_RS06715	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H9Q81_RS06720	COG0534	Mate efflux family protein
H9Q81_RS06735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9Q81_RS06745	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H9Q81_RS06755	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H9Q81_RS06790	COG2226	methyltransferase
H9Q81_RS06795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9Q81_RS06805	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H9Q81_RS06815	COG0681	Belongs to the peptidase S26 family
H9Q81_RS06820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9Q81_RS06825	COG0335	large ribosomal subunit rRNA binding
H9Q81_RS06850	COG1686	Belongs to the peptidase S11 family
H9Q81_RS06855	COG3119	arylsulfatase activity
H9Q81_RS06865	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H9Q81_RS06875	COG1115	amino acid carrier protein
H9Q81_RS06880	COG0822	iron-sulfur transferase activity
H9Q81_RS06885	COG1104	cysteine desulfurase activity
H9Q81_RS06890	COG0352	thiamine-phosphate diphosphorylase activity
H9Q81_RS06890	COG0351	phosphomethylpyrimidine kinase
H9Q81_RS06895	COG0352	thiamine-phosphate diphosphorylase activity
H9Q81_RS06900	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
H9Q81_RS06905	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H9Q81_RS06925	COG0733	neurotransmitter:sodium symporter activity
H9Q81_RS06930	COG0546	phosphoglycolate phosphatase activity
H9Q81_RS06935	COG1687	branched-chain amino acid
H9Q81_RS06940	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H9Q81_RS06950	COG0148	phosphopyruvate hydratase activity
H9Q81_RS06960	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
H9Q81_RS06965	COG2731	YhcH YjgK YiaL family protein
H9Q81_RS06975	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H9Q81_RS06975	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H9Q81_RS06995	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9Q81_RS07000	COG0428	transporter
H9Q81_RS07020	COG1278	Cold shock
H9Q81_RS07025	COG1477	protein flavinylation
H9Q81_RS07030	COG1758	RNA polymerase activity
H9Q81_RS07035	COG0194	GDP metabolic process
H9Q81_RS07040	COG2052	Domain of unknown function (DUF370)
H9Q81_RS07045	COG1561	YicC-like family, N-terminal region
H9Q81_RS07050	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H9Q81_RS07055	COG0085	RNA polymerase activity
H9Q81_RS07060	COG0222	ribosome binding
H9Q81_RS07065	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H9Q81_RS07070	COG0081	regulation of translation
H9Q81_RS07075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
H9Q81_RS07125	COG0495	leucyl-tRNA aminoacylation
H9Q81_RS07130	COG1595	DNA-templated transcription, initiation
H9Q81_RS07140	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H9Q81_RS07175	COG4464	protein tyrosine phosphatase activity
H9Q81_RS07210	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H9Q81_RS07220	COG2137	regulation of response to DNA damage stimulus
H9Q81_RS07225	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H9Q81_RS07250	COG0463	Glycosyl transferase, family 2
H9Q81_RS07255	COG0726	polysaccharide deacetylase
H9Q81_RS07265	COG1773	rubredoxin
H9Q81_RS07270	COG2033	superoxide reductase activity
H9Q81_RS07275	COG0735	belongs to the Fur family
H9Q81_RS07285	COG0101	tRNA pseudouridine synthase activity
H9Q81_RS07320	COG2885	chlorophyll binding
H9Q81_RS07340	COG0531	amino acid
H9Q81_RS07375	COG3475	LICD family
H9Q81_RS07410	COG1086	Polysaccharide biosynthesis protein
H9Q81_RS07425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H9Q81_RS07435	COG1086	Polysaccharide biosynthesis protein
H9Q81_RS07445	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
H9Q81_RS07460	COG1245	4Fe-4S binding domain
H9Q81_RS07460	COG2878	Part of a membrane complex involved in electron transport
H9Q81_RS07465	COG4657	Part of a membrane complex involved in electron transport
H9Q81_RS07470	COG4660	Part of a membrane complex involved in electron transport
H9Q81_RS07480	COG4658	electron transport chain
H9Q81_RS07485	COG4656	Part of a membrane complex involved in electron transport
H9Q81_RS07490	COG0193	aminoacyl-tRNA hydrolase activity
H9Q81_RS07495	COG1760	l-serine dehydratase
H9Q81_RS07510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9Q81_RS07510	COG0072	phenylalanine-tRNA ligase activity
H9Q81_RS07515	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H9Q81_RS07530	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H9Q81_RS07535	COG0187	DNA topoisomerase II activity
H9Q81_RS07555	COG1187	pseudouridine synthase activity
H9Q81_RS07565	COG1979	alcohol dehydrogenase
H9Q81_RS07585	COG0583	DNA-binding transcription factor activity
H9Q81_RS07590	COG1970	mechanosensitive ion channel activity
H9Q81_RS07595	COG0166	Belongs to the GPI family
H9Q81_RS07615	COG1263	PTS System
H9Q81_RS07615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q81_RS07630	COG1263	PTS System
H9Q81_RS07630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q81_RS07635	COG0647	UMP catabolic process
H9Q81_RS07640	COG2088	sporulation resulting in formation of a cellular spore
H9Q81_RS07645	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H9Q81_RS07650	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H9Q81_RS07655	COG3956	TIGRFAM MazG family protein
H9Q81_RS07660	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H9Q81_RS07665	COG0446	pyridine nucleotide-disulphide oxidoreductase
H9Q81_RS07680	COG2801	Transposase and inactivated derivatives
H9Q81_RS07695	COG0800	Aldolase
H9Q81_RS07720	COG1674	ftsk spoiiie
H9Q81_RS07730	COG2946	Replication initiation factor
H9Q81_RS07760	COG0741	lytic transglycosylase activity
H9Q81_RS07760	COG0791	NLP P60 protein
H9Q81_RS07790	COG0488	(ABC) transporter
H9Q81_RS07800	COG0445	tRNA wobble uridine modification
H9Q81_RS07805	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
H9Q81_RS07810	COG1847	R3H domain protein
H9Q81_RS07815	COG0706	membrane insertase activity
H9Q81_RS07820	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H9Q81_RS07825	COG0594	ribonuclease P activity
H9Q81_RS07870	COG1760	l-serine dehydratase
H9Q81_RS07880	COG4443	Transcriptional Coactivator p15 (PC4)
H9Q81_RS07890	COG3681	Belongs to the UPF0597 family
H9Q81_RS07895	COG3829	transcription factor binding
H9Q81_RS07905	COG0583	DNA-binding transcription factor activity
H9Q81_RS07920	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H9Q81_RS07920	COG1648	precorrin-2 dehydrogenase activity
H9Q81_RS07925	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H9Q81_RS07930	COG0113	porphobilinogen synthase activity
H9Q81_RS07950	COG0181	hydroxymethylbilane synthase activity
H9Q81_RS07955	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H9Q81_RS07960	COG0564	pseudouridine synthase activity
H9Q81_RS07970	COG0126	phosphoglycerate kinase activity
H9Q81_RS08005	COG1362	aminopeptidase activity
H9Q81_RS08015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9Q81_RS08020	COG4771	TonB-dependent receptor
H9Q81_RS08100	COG0572	uridine kinase
H9Q81_RS08140	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H9Q81_RS08145	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H9Q81_RS08150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H9Q81_RS08155	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H9Q81_RS08160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H9Q81_RS08165	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H9Q81_RS08170	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H9Q81_RS08175	COG1181	Belongs to the D-alanine--D-alanine ligase family
H9Q81_RS08190	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H9Q81_RS08195	COG0360	Binds together with S18 to 16S ribosomal RNA
H9Q81_RS08200	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H9Q81_RS08210	COG1609	Transcriptional regulator
H9Q81_RS08235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H9Q81_RS08240	COG1193	negative regulation of DNA recombination
H9Q81_RS08245	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
H9Q81_RS08260	COG0215	cysteine-tRNA ligase activity
H9Q81_RS08265	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
H9Q81_RS08270	COG1077	Cell shape determining protein MreB Mrl
H9Q81_RS08275	COG0470	DNA polymerase III
H9Q81_RS08310	COG1869	D-ribose catabolic process
H9Q81_RS08315	COG1129	ABC transporter
H9Q81_RS08320	COG1172	Belongs to the binding-protein-dependent transport system permease family
H9Q81_RS08335	COG3775	system Galactitol-specific IIC component
H9Q81_RS08345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9Q81_RS08350	COG0391	Required for morphogenesis under gluconeogenic growth conditions
H9Q81_RS08355	COG0731	radical SAM domain protein
H9Q81_RS08355	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H9Q81_RS08375	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H9Q81_RS08380	COG0051	transcription antitermination factor activity, RNA binding
H9Q81_RS08385	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H9Q81_RS08390	COG0088	Forms part of the polypeptide exit tunnel
H9Q81_RS08395	COG0089	rRNA binding
H9Q81_RS08400	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H9Q81_RS08405	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H9Q81_RS08410	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H9Q81_RS08415	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H9Q81_RS08420	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H9Q81_RS08425	COG0255	Belongs to the universal ribosomal protein uL29 family
H9Q81_RS08430	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H9Q81_RS08435	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
H9Q81_RS08445	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H9Q81_RS08450	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H9Q81_RS08455	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H9Q81_RS08460	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H9Q81_RS08465	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H9Q81_RS08470	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H9Q81_RS08475	COG1841	ribosomal large subunit assembly
H9Q81_RS08480	COG0200	Binds to the 23S rRNA
H9Q81_RS08485	COG0201	protein transport
H9Q81_RS08500	COG0395	ABC-type sugar transport system, permease component
H9Q81_RS08525	COG0563	adenylate kinase activity
H9Q81_RS08535	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H9Q81_RS08545	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H9Q81_RS08550	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H9Q81_RS08555	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H9Q81_RS08560	COG0202	RNA polymerase activity
H9Q81_RS08565	COG0203	ribosomal protein L17
H9Q81_RS08575	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H9Q81_RS08585	COG2855	membrane
H9Q81_RS08595	COG2211	Major facilitator Superfamily
H9Q81_RS08610	COG1609	Transcriptional regulator
H9Q81_RS08615	COG1272	protein, Hemolysin III
H9Q81_RS08620	COG1335	isochorismatase
H9Q81_RS08625	COG0052	Belongs to the universal ribosomal protein uS2 family
H9Q81_RS08630	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H9Q81_RS08635	COG0528	UMP kinase activity
H9Q81_RS08640	COG0233	cytoplasmic translational termination
H9Q81_RS08645	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H9Q81_RS08650	COG4589	Belongs to the CDS family
H9Q81_RS08655	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H9Q81_RS08660	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H9Q81_RS08665	COG0750	zinc metalloprotease
H9Q81_RS08670	COG2204	response regulator
H9Q81_RS08675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9Q81_RS08680	COG0358	DNA primase activity
H9Q81_RS08685	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H9Q81_RS08690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H9Q81_RS08740	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H9Q81_RS08750	COG0747	negative chemotaxis
H9Q81_RS08760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9Q81_RS08765	COG0444	Belongs to the ABC transporter superfamily
H9Q81_RS08770	COG4608	Belongs to the ABC transporter superfamily
H9Q81_RS08775	COG1473	amidohydrolase
H9Q81_RS08805	COG2827	Endonuclease containing a URI domain
H9Q81_RS08920	COG3304	Inner membrane component domain
H9Q81_RS08925	COG2239	Acts as a magnesium transporter
H9Q81_RS08940	COG1940	carbohydrate kinase activity
H9Q81_RS08960	COG4221	oxidoreductase activity
H9Q81_RS08965	COG1773	rubredoxin
H9Q81_RS08965	COG1592	Rubrerythrin
H9Q81_RS08970	COG1733	regulation of RNA biosynthetic process
H9Q81_RS09015	COG3647	Membrane
H9Q81_RS09040	COG1288	antiporter activity
H9Q81_RS09045	COG1752	Esterase of the alpha-beta hydrolase superfamily
H9Q81_RS09050	COG0488	(ABC) transporter
H9Q81_RS09055	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H9Q81_RS09060	COG0049	tRNA binding
H9Q81_RS09065	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H9Q81_RS09070	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H9Q81_RS09080	COG3959	Transketolase, thiamine diphosphate binding domain
H9Q81_RS09085	COG3958	Transketolase
H9Q81_RS09100	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H9Q81_RS09105	COG0497	DNA recombination
H9Q81_RS09110	COG4974	Belongs to the 'phage' integrase family
H9Q81_RS09115	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H9Q81_RS09120	COG1132	(ABC) transporter
H9Q81_RS09140	COG0848	biopolymer transport protein
H9Q81_RS09145	COG0811	peptide transport
H9Q81_RS09165	COG2832	Protein of unknown function (DUF454)
H9Q81_RS09170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H9Q81_RS09190	COG1288	antiporter activity
H9Q81_RS09195	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9Q81_RS09200	COG1263	PTS System
H9Q81_RS09200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9Q81_RS09200	COG2190	(PTS) system
H9Q81_RS09215	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H9Q81_RS09220	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H9Q81_RS09225	COG2011	ABC-type metal ion transport system permease component
H9Q81_RS09240	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H9Q81_RS09245	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
H9Q81_RS09245	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H9Q81_RS09280	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H9Q81_RS09290	COG1459	type II secretion system
H9Q81_RS09295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H9Q81_RS09310	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H9Q81_RS09325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9Q81_RS09340	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H9Q81_RS09345	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H9Q81_RS09360	COG0514	ATP-dependent DNA helicase (RecQ)
H9Q81_RS09365	COG0514	ATP-dependent DNA helicase (RecQ)
H9Q81_RS09405	COG1518	maintenance of DNA repeat elements
H9Q81_RS09410	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
H9Q81_RS09420	COG1105	Belongs to the carbohydrate kinase PfkB family
H9Q81_RS09430	COG2222	sugar isomerase
H9Q81_RS09435	COG1940	carbohydrate kinase activity
H9Q81_RS09445	COG3119	arylsulfatase activity
H9Q81_RS09450	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H9Q81_RS09455	COG2188	Transcriptional regulator
H9Q81_RS09460	COG0641	radical SAM
H9Q81_RS09465	COG5492	domain, Protein
H9Q81_RS09470	COG1028	Short-chain dehydrogenase reductase Sdr
H9Q81_RS09475	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
H9Q81_RS09480	COG3842	ATPase activity
H9Q81_RS09485	COG4209	transmembrane transport
H9Q81_RS09490	COG0395	ABC-type sugar transport system, permease component
H9Q81_RS09495	COG1653	transport
H9Q81_RS09505	COG5492	domain, Protein
H9Q81_RS09510	COG3119	arylsulfatase activity
H9Q81_RS09515	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H9Q81_RS09520	COG2211	Major facilitator Superfamily
H9Q81_RS09540	COG1653	transport
H9Q81_RS09565	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
H9Q81_RS09580	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
H9Q81_RS09585	COG3829	transcription factor binding
H9Q81_RS09590	COG0402	S-adenosylhomocysteine deaminase activity
H9Q81_RS09595	COG2233	PERMEase
H9Q81_RS09600	COG0167	dihydroorotate dehydrogenase activity
H9Q81_RS09615	COG0251	oxidation-reduction process
H9Q81_RS09625	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H9Q81_RS09630	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H9Q81_RS09635	COG0302	gtp cyclohydrolase
H9Q81_RS09640	COG0602	queuosine metabolic process
H9Q81_RS09645	COG0720	synthase
H9Q81_RS09655	COG5002	protein histidine kinase activity
H9Q81_RS09675	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H9Q81_RS09680	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H9Q81_RS09685	COG1393	Belongs to the ArsC family
H9Q81_RS09690	COG1114	Component of the transport system for branched-chain amino acids
H9Q81_RS09695	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
H9Q81_RS09710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9Q81_RS09715	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H9Q81_RS09730	COG0668	transmembrane transport
H9Q81_RS09735	COG0517	IMP dehydrogenase activity
H9Q81_RS09735	COG0516	GMP reductase activity
H9Q81_RS09745	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H9Q81_RS09760	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H9Q81_RS09770	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H9Q81_RS09775	COG2877	3-deoxy-8-phosphooctulonate synthase activity
H9Q81_RS09780	COG0517	IMP dehydrogenase activity
H9Q81_RS09780	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H9Q81_RS09790	COG1349	DNA-binding transcription factor activity
H9Q81_RS09795	COG1105	Belongs to the carbohydrate kinase PfkB family
H9Q81_RS09800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9Q81_RS09800	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9Q81_RS09800	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9Q81_RS09820	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9Q81_RS09830	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
H9Q81_RS09835	COG5002	protein histidine kinase activity
H9Q81_RS09840	COG0745	RESPONSE REGULATOR receiver
H9Q81_RS09845	COG1937	Protein conserved in bacteria
H9Q81_RS09850	COG2217	Heavy metal translocating P-type atpase
H9Q81_RS09855	COG2608	mercury ion transmembrane transporter activity
H9Q81_RS09885	COG0564	pseudouridine synthase activity
H9Q81_RS09890	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H9Q81_RS09895	COG0792	nuclease activity
H9Q81_RS09905	COG1040	competence protein
H9Q81_RS09915	COG0149	triose-phosphate isomerase activity
H9Q81_RS09925	COG5012	cobalamin binding
H9Q81_RS09930	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
H9Q81_RS09935	COG1193	negative regulation of DNA recombination
H9Q81_RS09945	COG1509	lysine 2,3-aminomutase activity
H9Q81_RS09950	COG0604	alcohol dehydrogenase
H9Q81_RS09955	COG3246	L-lysine catabolic process to acetate
H9Q81_RS09960	COG1607	acyl-coa hydrolase
H9Q81_RS09965	COG1757	Na H antiporter
H9Q81_RS09975	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H9Q81_RS09980	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H9Q81_RS09990	COG0521	Mo-molybdopterin cofactor biosynthetic process
H9Q81_RS09995	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H9Q81_RS10000	COG0268	Binds directly to 16S ribosomal RNA
H9Q81_RS10025	COG0058	SHG alpha-glucan phosphorylase activity
H9Q81_RS10030	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H9Q81_RS10035	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H9Q81_RS10040	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H9Q81_RS10045	COG0297	glycogen (starch) synthase activity
H9Q81_RS10050	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
H9Q81_RS10060	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
H9Q81_RS10065	COG0583	DNA-binding transcription factor activity
H9Q81_RS10070	COG0561	phosphatase activity
H9Q81_RS10080	COG0525	valine-tRNA ligase activity
H9Q81_RS10085	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H9Q81_RS10090	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H9Q81_RS10095	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H9Q81_RS10100	COG0740	serine-type endopeptidase activity
H9Q81_RS10105	COG0544	peptidyl-prolyl cis-trans isomerase activity
H9Q81_RS10110	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H9Q81_RS10110	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H9Q81_RS10115	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H9Q81_RS10120	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H9Q81_RS10130	COG0195	Participates in both transcription termination and antitermination
H9Q81_RS10135	COG0779	Required for maturation of 30S ribosomal subunits
H9Q81_RS10140	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H9Q81_RS10175	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H9Q81_RS10185	COG1160	GTP binding
H9Q81_RS10190	COG1032	radical SAM domain protein