locus-tag	class	description
HX109_RS00010	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HX109_RS00020	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HX109_RS00030	ENOG4105C84	Histidine ammonia-lyase
HX109_RS00035	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HX109_RS00040	ENOG4105CFH	Aspartokinase
HX109_RS00045	ENOG4107RDY	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HX109_RS00050	ENOG4105D98	threonine synthase
HX109_RS00070	ENOG4105D64	Mechanosensitive ion channel
HX109_RS00075	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HX109_RS00105	ENOG4105ER2	Ompa motb domain protein
HX109_RS00110	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HX109_RS00120	ENOG4105CJ1	ABC, transporter
HX109_RS00125	ENOG4107QWP	ABC-2 type transporter
HX109_RS00130	ENOG4105CJ1	ABC, transporter
HX109_RS00135	ENOG4105CJ1	ABC, transporter
HX109_RS00140	ENOG4105D0S	secretion protein (HlyD
HX109_RS00160	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HX109_RS00180	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HX109_RS00185	ENOG4107XI7	Tetr family transcriptional regulator
HX109_RS00205	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HX109_RS00220	ENOG4105E0X	reductase
HX109_RS00255	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
HX109_RS00260	ENOG4105FFC	UPF0187 protein
HX109_RS00275	ENOG4105CUT	histidyl-tRNA synthetase
HX109_RS00285	ENOG4108KPZ	tonB-dependent Receptor
HX109_RS00290	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HX109_RS00295	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HX109_RS00300	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
HX109_RS00305	ENOG4108NEV	two component transcriptional regulator, LytTR family
HX109_RS00310	ENOG4105C25	Primosomal protein n'
HX109_RS00320	ENOG4105DXN	mazG family
HX109_RS00345	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HX109_RS00355	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HX109_RS00360	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HX109_RS00365	ENOG4106WTF	Glycosyl transferase, family 2
HX109_RS00370	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HX109_RS00380	ENOG4107SJB	teichoic acid biosynthesis
HX109_RS00395	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HX109_RS00425	ENOG4107QI6	Cysteine desulfurase
HX109_RS00455	ENOG4105C8Y	Acetylornithine aminotransferase
HX109_RS00480	ENOG4108UB4	uncharacterized protein ygjQ
HX109_RS00485	ENOG4105C1G	acyl-Coa dehydrogenase
HX109_RS00490	ENOG4105CHU	acetyl-coa acetyltransferase
HX109_RS00510	ENOG4108IQE	Amp-dependent synthetase and ligase
HX109_RS00515	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
HX109_RS00530	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HX109_RS00555	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HX109_RS00560	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
HX109_RS00565	ENOG41075SV	phosphoribosyltransferase
HX109_RS00570	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HX109_RS00580	ENOG4108RWN	rrna methyltransferase
HX109_RS00595	ENOG4105CI2	imidazolone-5-propionate hydrolase
HX109_RS00605	ENOG4105CIN	aminoacyl-histidine dipeptidase
HX109_RS00610	ENOG4105BZU	Histidine kinase
HX109_RS00650	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HX109_RS00680	ENOG4107VIJ	nudix hydrolase
HX109_RS00685	ENOG4105BZP	glycoside hydrolase 15-related
HX109_RS00690	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
HX109_RS00760	ENOG4107SFQ	iron-sulfur binding
HX109_RS00775	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HX109_RS00795	ENOG4105EXW	epimerase dehydratase
HX109_RS00805	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HX109_RS00820	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HX109_RS00825	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HX109_RS00830	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HX109_RS00850	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HX109_RS00870	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
HX109_RS00930	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HX109_RS00945	ENOG4105ENH	Sulfatase
HX109_RS00950	ENOG4105ENH	Sulfatase
HX109_RS00980	ENOG4105EMN	RNA polymerase sigma factor
HX109_RS01010	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HX109_RS01015	ENOG4105CAQ	asparagine synthetase
HX109_RS01030	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HX109_RS01035	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
HX109_RS01040	ENOG4105D7Z	glutathione synthase
HX109_RS01050	ENOG4105BZU	Histidine kinase
HX109_RS01065	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
HX109_RS01085	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HX109_RS01095	ENOG4108CSZ	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HX109_RS01115	ENOG4105DY9	regulatoR
HX109_RS01130	ENOG4108HRK	Histidine kinase
HX109_RS01140	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
HX109_RS01155	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HX109_RS01160	ENOG4105C2X	Arabinose 5-phosphate isomerase
HX109_RS01165	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HX109_RS01175	ENOG4108IUZ	ABC transporter
HX109_RS01180	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
HX109_RS01195	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HX109_RS01200	ENOG4107RDT	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HX109_RS01205	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HX109_RS01210	ENOG4105VG0	50S ribosomal protein l34
HX109_RS01225	ENOG4105CSR	polyphosphate kinase 2
HX109_RS01245	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HX109_RS01255	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HX109_RS01290	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HX109_RS01295	ENOG4108MJ3	acetyltransferase
HX109_RS01300	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HX109_RS01310	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HX109_RS01320	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HX109_RS01340	ENOG4105HHA	aminodeoxychorismate lyase
HX109_RS01350	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HX109_RS01355	ENOG4105C0H	protease
HX109_RS01380	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HX109_RS01385	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HX109_RS01390	ENOG4105E9K	Isocitrate dehydrogenase
HX109_RS01405	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HX109_RS01425	ENOG4105CPK	Glycosyl transferase (Group 1
HX109_RS01440	ENOG4105DF6	Fe-S oxidoreductase
HX109_RS01450	ENOG4105DF6	Fe-S oxidoreductase
HX109_RS01460	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
HX109_RS01475	ENOG4105E98	transcriptional regulator DeoR family
HX109_RS01490	ENOG4105F32	YngK protein
HX109_RS01505	ENOG4105CTQ	phosphohexokinase
HX109_RS01515	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HX109_RS01545	ENOG4105EFZ	amidohydrolase
HX109_RS01590	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
HX109_RS01600	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HX109_RS01615	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HX109_RS01620	ENOG4105EFX	secretion protein, HlyD family
HX109_RS01630	ENOG4107QTF	adenylosuccinate lyase
HX109_RS01645	ENOG4105KPY	Small multidrug resistance protein
HX109_RS01660	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HX109_RS01670	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HX109_RS01675	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HX109_RS01685	ENOG41083ND	50S ribosomal protein L33
HX109_RS01690	ENOG4105KDC	50s ribosomal protein l28
HX109_RS01695	ENOG4105CEV	competence damage-inducible protein
HX109_RS01710	ENOG4108IRC	dna polymerase iii
HX109_RS01720	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HX109_RS01725	ENOG4107RJ1	sodium solute
HX109_RS01800	ENOG4105VUH	addiction module killer protein
HX109_RS01810	ENOG4105CDU	Replicative dna helicase
HX109_RS01815	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HX109_RS01830	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HX109_RS01835	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HX109_RS01840	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HX109_RS01855	ENOG4105VEJ	Heat shock protein
HX109_RS01860	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HX109_RS01865	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HX109_RS01895	ENOG4106CC8	Bacterial inner membrane protein
HX109_RS01905	ENOG41061CK	Antibiotic biosynthesis monooxygenase
HX109_RS01910	ENOG4105CI3	gtp-binding protein typa
HX109_RS01915	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HX109_RS01955	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HX109_RS01960	ENOG4105VJV	50s ribosomal protein L35
HX109_RS01965	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HX109_RS01970	ENOG4105C22	threonyL-tRNA synthetase
HX109_RS02035	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HX109_RS02040	ENOG4105D5P	Methylmalonyl-coA mutase
HX109_RS02055	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
HX109_RS02060	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HX109_RS02080	ENOG4107R5B	glutamine synthetase
HX109_RS02090	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HX109_RS02120	ENOG4105DJV	ribulose-phosphate 3-epimerase
HX109_RS02125	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
HX109_RS02145	ENOG4105E2D	ec 3.2.1.52
HX109_RS02175	ENOG4105C9F	isomerase
HX109_RS02185	ENOG4105DMF	Dehydrogenase
HX109_RS02190	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HX109_RS02200	ENOG410605W	Major Facilitator
HX109_RS02210	ENOG41089UC	methyltransferase, type 11
HX109_RS02240	ENOG4105C5H	ABC transporter
HX109_RS02250	ENOG4108WBT	adenosyltransferase
HX109_RS02260	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HX109_RS02275	ENOG4105EMN	RNA polymerase sigma factor
HX109_RS02300	ENOG4105EMN	RNA polymerase sigma factor
HX109_RS02305	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HX109_RS02310	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HX109_RS02320	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HX109_RS02330	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HX109_RS02340	ENOG4105CKK	Glycosyl transferase, family 2
HX109_RS02345	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HX109_RS02375	ENOG4107QN2	dihydrolipoyl dehydrogenase
HX109_RS02385	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HX109_RS02400	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HX109_RS02410	ENOG4105WZW	rhodanese family
HX109_RS02430	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HX109_RS02435	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HX109_RS02500	ENOG4105R48	this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase
HX109_RS02525	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HX109_RS02530	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HX109_RS02540	ENOG4105KNE	Phosphatidate cytidylyltransferase
HX109_RS02545	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
HX109_RS02555	ENOG41082BM	Transcriptional regulator, arsr family
HX109_RS02565	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HX109_RS02575	ENOG4105DZP	Membrane-associated zinc metalloprotease
HX109_RS02580	ENOG4105CHM	Aminotransferase
HX109_RS02585	ENOG4107R0I	Cell wall formation (By similarity)
HX109_RS02590	ENOG4105K6V	RNA polymerase
HX109_RS02605	ENOG4108JJA	ABC, transporter
HX109_RS02630	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HX109_RS02640	ENOG4105UQX	Mate efflux family protein
HX109_RS02655	ENOG4105C75	arginyL-tRNA synthetase
HX109_RS02665	ENOG4105C94	Transporter
HX109_RS02710	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HX109_RS02715	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HX109_RS02720	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HX109_RS02725	ENOG4108ZT0	50S ribosomal protein l17
HX109_RS02730	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HX109_RS02735	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HX109_RS02740	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HX109_RS02745	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HX109_RS02750	ENOG410864M	50S ribosomal protein L36
HX109_RS02755	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HX109_RS02760	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HX109_RS02765	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HX109_RS02770	ENOG41084HK	50S ribosomal protein L30
HX109_RS02775	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HX109_RS02780	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HX109_RS02785	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HX109_RS02790	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HX109_RS02795	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HX109_RS02800	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HX109_RS02805	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HX109_RS02810	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HX109_RS02815	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HX109_RS02820	ENOG4105WNB	50s ribosomal protein l29
HX109_RS02825	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HX109_RS02830	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HX109_RS02835	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HX109_RS02840	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HX109_RS02845	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HX109_RS02850	ENOG41082S5	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HX109_RS02855	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HX109_RS02860	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HX109_RS02865	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HX109_RS02870	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HX109_RS02875	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HX109_RS02880	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HX109_RS02885	ENOG4105C27	TonB-dependent Receptor Plug
HX109_RS02915	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HX109_RS02925	ENOG4105D1H	recombination factor protein RarA
HX109_RS02955	ENOG4105W5Q	DNA repair protein (RadC
HX109_RS02975	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
HX109_RS02980	ENOG4105DFU	Cell wall formation (By similarity)
HX109_RS02995	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HX109_RS03000	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HX109_RS03010	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HX109_RS03040	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HX109_RS03045	ENOG4105DGW	oligopeptidase A
HX109_RS03075	ENOG4105CGP	Urocanate hydratase
HX109_RS03090	ENOG4105K6H	D-cysteine desulfhydrase
HX109_RS03100	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HX109_RS03115	ENOG41083X6	30S ribosomal protein S21
HX109_RS03120	ENOG4105VEQ	Cold shock protein
HX109_RS03125	ENOG4105CH6	catalase
HX109_RS03140	ENOG4105C59	p-type ATPase
HX109_RS03165	ENOG4105C58	cytochrome c oxidase accessory protein ccog
HX109_RS03180	ENOG4105D4P	Coproporphyrinogen iii oxidase
HX109_RS03210	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HX109_RS03240	ENOG4105EPC	oxidoreductase
HX109_RS03275	ENOG4105C5H	ABC transporter
HX109_RS03285	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HX109_RS03305	ENOG4105E6M	Sulphatase-modifying factor protein
HX109_RS03330	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HX109_RS03355	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HX109_RS03360	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HX109_RS03370	ENOG4105EUB	pirin domain protein
HX109_RS03380	ENOG4108ZGC	gaf domain protein
HX109_RS03385	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HX109_RS03390	ENOG4105DFF	Rod shape-determining protein mreb
HX109_RS03400	ENOG4107RVG	penicillin-binding protein
HX109_RS03405	ENOG4105CNI	cell division protein FtsW
HX109_RS03410	ENOG4105CN1	protease
HX109_RS03420	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HX109_RS03430	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HX109_RS03435	ENOG4107TT5	NLP P60 protein
HX109_RS03440	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
HX109_RS03445	ENOG4105DUX	Transporter
HX109_RS03450	ENOG4105C5Z	peptidase
HX109_RS03455	ENOG4105D78	K07001 NTE family protein
HX109_RS03460	ENOG4107EEU	hydroxymethylglutaryL-CoA reductase
HX109_RS03485	ENOG4108JU5	Magnesium and cobalt efflux protein
HX109_RS03510	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HX109_RS03545	ENOG4107QJZ	Glycosyl transferase, family 2
HX109_RS03555	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HX109_RS03565	ENOG4105BZU	Histidine kinase
HX109_RS03570	ENOG4105DZP	Membrane-associated zinc metalloprotease
HX109_RS03580	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HX109_RS03585	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HX109_RS03595	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HX109_RS03635	ENOG4105CAY	ferredoxin--nadp reductase
HX109_RS03640	ENOG4108ZIT	Ferredoxin, 2FE-2S
HX109_RS03655	ENOG4105DZG	Dehydrogenase
HX109_RS03695	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HX109_RS03720	ENOG4105C26	Dehydrogenase
HX109_RS03725	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
HX109_RS03730	ENOG4108VVK	transcriptional Regulator, AsnC
HX109_RS03735	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HX109_RS03740	ENOG4105DWY	Agmatine deiminase
HX109_RS03750	ENOG4107S6Z	Na H antiporter
HX109_RS03800	ENOG4107RJ9	Cell division protein FtsX
HX109_RS03810	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HX109_RS03815	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HX109_RS03830	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HX109_RS03835	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HX109_RS03845	ENOG4107XC4	flavin reductase domain protein, FMN-binding
HX109_RS03850	ENOG4108HWS	Histidine kinase
HX109_RS03865	ENOG4105K63	Thioredoxin
HX109_RS03875	ENOG4106210	phosphatase activity
HX109_RS03890	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HX109_RS03900	ENOG4105CMR	udp-glucose 4-epimerase
HX109_RS03905	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HX109_RS03920	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
HX109_RS03925	ENOG4108JA2	transcriptioN-repair coupling factor
HX109_RS03940	ENOG41080R2	UPF0102 protein
HX109_RS03955	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HX109_RS03960	ENOG4105DGU	Histone deacetylase
HX109_RS03975	ENOG41090A1	ferritin
HX109_RS03985	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
HX109_RS04005	ENOG4107SRH	Nad-dependent epimerase dehydratase
HX109_RS04015	ENOG4105C9K	Endothelin-converting enzyme 1
HX109_RS04025	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HX109_RS04030	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
HX109_RS04045	ENOG4105D06	uba thif-type nad fad binding protein
HX109_RS04050	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HX109_RS04060	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HX109_RS04075	ENOG4108HKT	sucrose-6-phosphate hydrolase
HX109_RS04100	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
HX109_RS04105	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HX109_RS04115	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HX109_RS04120	ENOG4105CBG	Sulfatase
HX109_RS04130	ENOG4107QZF	nitrite reductase NADPH large subunit
HX109_RS04160	ENOG4105FE9	pseudouridine synthase
HX109_RS04175	ENOG4105CDV	Ompa motb domain protein
HX109_RS04225	ENOG4105KAV	tspo and mbr like protein
HX109_RS04230	ENOG4105CBX	hi0933 family
HX109_RS04260	ENOG4108IUK	alpha amylase, catalytic
HX109_RS04275	ENOG4107URF	beta-phospho-glucomutase
HX109_RS04295	ENOG4105ETE	Transcriptional regulator (LacI family
HX109_RS04300	ENOG4105C27	TonB-dependent Receptor Plug
HX109_RS04385	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HX109_RS04395	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HX109_RS04400	ENOG4107RWD	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HX109_RS04405	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HX109_RS04420	ENOG4105SF0	DinB family
HX109_RS04440	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HX109_RS04450	ENOG4105FAA	peptidase M23
HX109_RS04455	ENOG4105CPC	Aldo Keto reductase
HX109_RS04460	ENOG4105ER2	Ompa motb domain protein
HX109_RS04465	ENOG4105CGK	Exodeoxyribonuclease III
HX109_RS04485	ENOG4105K63	Thioredoxin
HX109_RS04490	ENOG4107RN3	metallophosphoesterase
HX109_RS04495	ENOG4105C2M	dna polymerase I
HX109_RS04520	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HX109_RS04525	ENOG4108UJD	30S ribosomal protein S9
HX109_RS04530	ENOG4105CE9	30S ribosomal protein S2
HX109_RS04535	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HX109_RS04540	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HX109_RS04545	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HX109_RS04560	ENOG4105C5S	asparaginyl-tRNA synthetase
HX109_RS04565	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HX109_RS04605	ENOG4105HDK	L-asparaginase
HX109_RS04615	ENOG4105F8V	Hydrolase, tatD family
HX109_RS04625	ENOG4105C7S	Dehydrogenase
HX109_RS04630	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HX109_RS04655	ENOG4105EAA	nucleoside
HX109_RS04685	ENOG41061MV	Arylsulfatase
HX109_RS04700	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HX109_RS04705	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HX109_RS04710	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HX109_RS04715	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HX109_RS04720	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HX109_RS04735	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HX109_RS04750	ENOG4105BZS	acriflavin resistance protein
HX109_RS04765	ENOG4105XEA	Tetr family transcriptional regulator
HX109_RS04800	ENOG4105CE1	Ferrous iron transport protein b
HX109_RS04815	ENOG4108KF3	Electron transport protein SCO1 SenC
HX109_RS04820	ENOG4105DZP	Membrane-associated zinc metalloprotease
HX109_RS04850	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HX109_RS04990	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HX109_RS05000	ENOG4105D05	Receptor
HX109_RS05050	ENOG4105DEN	Luciferase family
HX109_RS05065	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HX109_RS05075	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HX109_RS05080	ENOG4108ZG0	Ompa motb domain protein
HX109_RS05120	ENOG4107YB6	acetyltransferase, (GNAT) family
HX109_RS05145	ENOG4105KRF	dihydroneopterin aldolase
HX109_RS05150	ENOG4105D41	biosynthesis protein thiH
HX109_RS05155	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HX109_RS05160	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HX109_RS05165	ENOG4105DWF	phosphomethylpyrimidine kinase
HX109_RS05175	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HX109_RS05185	ENOG4105SXS	Protein of unknown function (DUF456)
HX109_RS05195	ENOG4105WXV	50S ribosomal protein L32
HX109_RS05200	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HX109_RS05205	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HX109_RS05210	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HX109_RS05215	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HX109_RS05235	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HX109_RS05240	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HX109_RS05245	ENOG4107Z4P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HX109_RS05250	ENOG4107Z65	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
HX109_RS05255	ENOG4105VHG	atp synthase
HX109_RS05260	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
HX109_RS05290	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HX109_RS05300	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
HX109_RS05305	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HX109_RS05315	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HX109_RS05330	ENOG4105CTU	Proline racemase
HX109_RS05335	ENOG4107QMZ	Dehydrogenase
HX109_RS05345	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HX109_RS05350	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HX109_RS05370	ENOG4105CSA	Coproporphyrinogen iii oxidase
HX109_RS05430	ENOG4107QRT	dEAD DEAH box helicase
HX109_RS05435	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
HX109_RS05440	ENOG4107T0X	DNA ligase
HX109_RS05445	ENOG4105K5M	30s ribosomal protein S16
HX109_RS05450	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HX109_RS05455	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
HX109_RS05475	ENOG4105C1G	acyl-Coa dehydrogenase
HX109_RS05485	ENOG4108IPT	Naphthoate synthase
HX109_RS05520	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HX109_RS05525	ENOG4107SN7	NLP P60 protein
HX109_RS05530	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HX109_RS05555	ENOG4105C8F	Beta-lactamase domain protein
HX109_RS05570	ENOG4105WG6	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HX109_RS05575	ENOG4105CN1	protease
HX109_RS05600	ENOG4105CD3	dihydroorotase
HX109_RS05605	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
HX109_RS05625	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HX109_RS05630	ENOG4105UYK	outer membrane protein a
HX109_RS05645	ENOG4107QRG	dna polymerase iii
HX109_RS05650	ENOG4105BZA	Phosphoglycerate kinase
HX109_RS05655	ENOG4107X35	defense response to bacterium
HX109_RS05665	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HX109_RS05670	ENOG41063SB	peptidase
HX109_RS05700	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HX109_RS05715	ENOG4108Z4V	iron-sulfur cluster assembly
HX109_RS05750	ENOG4105C34	Pseudouridine synthase
HX109_RS05770	ENOG4105C9B	Cysteine desulfurase
HX109_RS05785	ENOG4105C8T	Leucyl-tRNA synthetase
HX109_RS05790	ENOG4105DCF	alanine dehydrogenase
HX109_RS05800	ENOG4108VVK	transcriptional Regulator, AsnC
HX109_RS05815	ENOG4105M08	Membrane
HX109_RS05825	ENOG4108R6K	riboflavin synthase, subunit alpha
HX109_RS05830	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HX109_RS05840	ENOG4105CCN	Peptidase M56
HX109_RS05855	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HX109_RS05865	ENOG4105PGM	cation diffusion facilitator family transporter
HX109_RS05870	ENOG4108YZG	isomerase
HX109_RS05880	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HX109_RS05915	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HX109_RS05920	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HX109_RS05930	ENOG4105EEF	Alkane 1-monooxygenase
HX109_RS05985	ENOG4105CKW	Inner membrane protein yedI
HX109_RS05990	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HX109_RS06015	ENOG4105CX6	glutaminyL-tRNA synthetase
HX109_RS06045	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HX109_RS06050	ENOG4108ZVT	methylmalonyl-coA epimerase
HX109_RS06055	ENOG41082IR	Excinuclease ABC C subunit domain protein
HX109_RS06090	ENOG4105E18	UPF0276 protein
HX109_RS06095	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HX109_RS06125	ENOG4105C31	Tryptophanyl-tRNA synthetase
HX109_RS06140	ENOG4105NAU	thioesterase Superfamily protein
HX109_RS06175	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HX109_RS06210	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HX109_RS06215	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HX109_RS06225	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HX109_RS06230	ENOG4107T8J	thymidine kinase
HX109_RS06255	ENOG4108RG0	uracil-dna glycosylase
HX109_RS06265	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HX109_RS06270	ENOG4105E0X	reductase
HX109_RS06275	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HX109_RS06280	ENOG4105CNG	UPF0061 protein
HX109_RS06300	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HX109_RS06310	ENOG4105EYW	Ion transport protein
HX109_RS06315	ENOG4107S9D	Alpha beta hydrolase
HX109_RS06320	ENOG4105EVH	UPF0753 protein
HX109_RS06325	ENOG4105D65	subunit l
HX109_RS06335	ENOG4105DUM	transcriptional regulator, lysR family
HX109_RS06340	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HX109_RS06345	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
HX109_RS06360	ENOG4105C72	UPF0176 protein
HX109_RS06365	ENOG4105MA4	psp1 domain protein
HX109_RS06370	ENOG410647Z	gliding motility-associated lipoprotein GldH
HX109_RS06375	ENOG4108JQC	penicillin-binding protein 1A
HX109_RS06380	ENOG4108RWI	nicotinamidase
HX109_RS06390	ENOG4105CPN	adenine deaminase
HX109_RS06395	ENOG4107QP7	CoA-transferase subunit A
HX109_RS06400	ENOG4107QNJ	CoA-transferase subunit B
HX109_RS06415	ENOG4107QN1	sodium solute
HX109_RS06420	ENOG4105E33	succinate dehydrogenase
HX109_RS06440	ENOG4107RAQ	aminopeptidase
HX109_RS06455	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HX109_RS06460	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HX109_RS06465	ENOG4105VG1	fes assembly suf system protein
HX109_RS06490	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HX109_RS06530	ENOG4105D52	delta-aminolevulinic acid dehydratase
HX109_RS06540	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HX109_RS06555	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HX109_RS06575	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HX109_RS06580	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HX109_RS06595	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HX109_RS06600	ENOG4107QMU	Mate efflux family protein
HX109_RS06620	ENOG4105CN1	protease
HX109_RS06640	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HX109_RS06650	ENOG4108Y6J	UPF0403 protein
HX109_RS06710	ENOG4105E39	Enoyl-CoA hydratase
HX109_RS06715	ENOG4108HWS	Histidine kinase
HX109_RS06730	ENOG41081FY	multiple antibiotic resistance (MarC)-related
HX109_RS06750	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HX109_RS06785	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HX109_RS06795	ENOG4108Z6B	deaminase
HX109_RS06805	ENOG4105VEQ	Cold shock protein
HX109_RS06830	ENOG4105C9M	aspartyl-trna synthetase
HX109_RS06840	ENOG4105DSJ	YicC domain protein
HX109_RS06845	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HX109_RS06855	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HX109_RS06860	ENOG4109066	lysm domain bon superfamily protein
HX109_RS06865	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HX109_RS06890	ENOG4105ENE	Histidine kinase
HX109_RS06925	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HX109_RS06930	ENOG4108JQB	penicillin-binding protein 1C
HX109_RS06935	ENOG4105DN3	alpha-2-macroglobulin domain protein
HX109_RS06940	ENOG4105D44	asparaginase
HX109_RS06950	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
HX109_RS06965	ENOG4105C26	Dehydrogenase
HX109_RS06985	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HX109_RS07000	ENOG4105EMU	Dehydrogenase
HX109_RS07005	ENOG4107QM2	Aldo Keto reductase
HX109_RS07015	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HX109_RS07030	ENOG4107QVM	von Willebrand factor, type A
HX109_RS07035	ENOG4107QVM	von Willebrand factor, type A
HX109_RS07065	ENOG41077A9	carbonic anhydrase
HX109_RS07075	ENOG4105CGD	Nad-dependent epimerase dehydratase
HX109_RS07080	ENOG4105E96	Colicin v production protein
HX109_RS07090	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HX109_RS07100	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HX109_RS07115	ENOG410624X	efflux transporter, rnd family, mfp subunit
HX109_RS07125	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HX109_RS07130	ENOG4105HFZ	Membrane
HX109_RS07140	ENOG4105W2Z	cytochrome C, class I
HX109_RS07145	ENOG4105DNZ	Alpha Beta Hydrolase
HX109_RS07175	ENOG4105C28	cystathionine
HX109_RS07180	ENOG4107R37	Glutamate dehydrogenase
HX109_RS07190	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
HX109_RS07195	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HX109_RS07210	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HX109_RS07215	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HX109_RS07230	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HX109_RS07240	ENOG4105F1J	Homogentisate 1,2-dioxygenase
HX109_RS07245	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
HX109_RS07265	ENOG4107QP8	phosphohexose isomerase
HX109_RS07315	ENOG4105MJ2	Competence protein
HX109_RS07325	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
HX109_RS07335	ENOG4105BZU	Histidine kinase
HX109_RS07350	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HX109_RS07375	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
HX109_RS07380	ENOG4105CHV	Transcription elongation factor NusA
HX109_RS07385	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HX109_RS07400	ENOG4107SFQ	iron-sulfur binding
HX109_RS07405	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HX109_RS07425	ENOG4105E2S	oxidase) subunit II
HX109_RS07430	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HX109_RS07440	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HX109_RS07455	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
HX109_RS07475	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HX109_RS07485	ENOG4107RY6	amino acid
HX109_RS07515	ENOG4105DVT	helicase
HX109_RS07525	ENOG4105C6Z	Gluconate
HX109_RS07550	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HX109_RS07560	ENOG4105DQ4	alcohol dehydrogenase
HX109_RS07565	ENOG4105C03	ribonuclease
HX109_RS07580	ENOG4108UUM	single-stranded DNA-binding protein
HX109_RS07585	ENOG4108JU5	Magnesium and cobalt efflux protein
HX109_RS07620	ENOG4105D05	Receptor
HX109_RS07640	ENOG4105C1V	Peptidase, M16
HX109_RS07655	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HX109_RS07660	ENOG4105K46	50S ribosomal protein l27
HX109_RS07680	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HX109_RS07690	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HX109_RS07705	ENOG4105C6K	Malic enzyme
HX109_RS07710	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HX109_RS07720	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HX109_RS07740	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HX109_RS07750	ENOG4105CCU	oxidase (Subunit III)
HX109_RS07765	ENOG4108KF3	Electron transport protein SCO1 SenC
HX109_RS07770	ENOG4108SJC	Membrane
HX109_RS07780	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HX109_RS07785	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HX109_RS07790	ENOG4107RBB	ABC transporter, permease
HX109_RS07795	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HX109_RS07805	ENOG41072GX	Peptidase M22 Glycoprotease
HX109_RS07810	ENOG4105D64	Mechanosensitive ion channel
HX109_RS07830	ENOG41083MR	nifu domain-containing protein
HX109_RS07840	ENOG4108Z0R	Transferase
HX109_RS07845	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HX109_RS07865	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
HX109_RS07875	ENOG4105E9M	CRISPR-associated protein, Csn1 family
HX109_RS07950	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HX109_RS07965	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HX109_RS07970	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HX109_RS07975	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HX109_RS07990	ENOG4105DTN	riboflavin biosynthesis protein ribF
HX109_RS08010	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HX109_RS08025	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HX109_RS08030	ENOG4105CJW	magnesium transporter
HX109_RS08040	ENOG4108JQ1	Dehydrogenase
HX109_RS08065	ENOG4105CFH	Aspartokinase
HX109_RS08075	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HX109_RS08090	ENOG4105C0B	DNA polymerase III (alpha subunit)
HX109_RS08105	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HX109_RS08135	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
HX109_RS08160	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HX109_RS08165	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HX109_RS08170	ENOG4105BZU	Histidine kinase
HX109_RS08175	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HX109_RS08200	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HX109_RS08205	ENOG4105C94	Transporter
HX109_RS08215	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
HX109_RS08225	ENOG4105DG6	mannose-6-phosphate isomerase
HX109_RS08245	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HX109_RS08290	ENOG4105C1G	acyl-Coa dehydrogenase
HX109_RS08295	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HX109_RS08300	ENOG4105D82	Glutamate dehydrogenase
HX109_RS08305	ENOG4105DN9	Na H antiporter
HX109_RS08315	ENOG4109015	Biopolymer transport protein exbD tolR
HX109_RS08325	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HX109_RS08340	ENOG4108UT2	hemolysin iii
HX109_RS08355	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HX109_RS08385	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HX109_RS08405	ENOG4105C5Q	Transcriptional regulator
HX109_RS08420	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HX109_RS08450	ENOG4105EN6	Membrane
HX109_RS08455	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HX109_RS08485	ENOG4105CEP	NADH dehydrogenase
HX109_RS08490	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HX109_RS08500	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HX109_RS08505	ENOG41086DT	Membrane protein of unknown function
HX109_RS08525	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HX109_RS08535	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HX109_RS08545	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HX109_RS08550	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HX109_RS08565	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HX109_RS08580	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HX109_RS08690	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
HX109_RS08695	ENOG4105E6M	Sulphatase-modifying factor protein
HX109_RS08735	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
HX109_RS08750	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HX109_RS08755	ENOG41062IR	nudix hydrolase
HX109_RS08765	ENOG4105CHH	sulfate transporter
HX109_RS08770	ENOG4105WH1	Two component transcriptional regulator luxr family
HX109_RS08780	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HX109_RS08785	ENOG4105CPF	Cell wall formation (By similarity)
HX109_RS08790	ENOG4105D9P	serine threonine protein kinase
HX109_RS08795	ENOG4105C34	Pseudouridine synthase
HX109_RS08800	ENOG4105D1Q	UPF0246 protein
HX109_RS08820	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HX109_RS08825	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HX109_RS08830	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HX109_RS08835	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HX109_RS08845	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HX109_RS08855	ENOG4105DDQ	anthranilate synthase
HX109_RS08860	ENOG4105CRQ	synthase (Component I)
HX109_RS08865	ENOG4108YYC	ycei family
HX109_RS08870	ENOG4108RCM	Nitroreductase
HX109_RS08880	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HX109_RS08910	ENOG4105BZG	amino acid carrier protein
HX109_RS08920	ENOG4105C1G	acyl-Coa dehydrogenase
HX109_RS08925	ENOG41083X6	30S ribosomal protein S21
HX109_RS08930	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HX109_RS08935	ENOG4105MS2	ribosomal subunit Interface protein
HX109_RS08960	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HX109_RS08980	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HX109_RS08985	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HX109_RS08990	ENOG4107VNI	ribosomal protein l10
HX109_RS08995	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HX109_RS09000	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HX109_RS09005	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HX109_RS09025	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HX109_RS09030	ENOG4105BZ1	(ABC) transporter
HX109_RS09080	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
HX109_RS09105	ENOG4105EGD	dinuclear metal center protein, YbgI family
HX109_RS09110	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HX109_RS09115	ENOG4105BZU	Histidine kinase
HX109_RS09120	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HX109_RS09125	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HX109_RS09130	ENOG4105K3M	)-transporter
HX109_RS09150	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HX109_RS09155	ENOG41061MV	Arylsulfatase
HX109_RS09160	ENOG4107QZ2	Sulfatase
HX109_RS09165	ENOG4105CBG	Sulfatase
HX109_RS09180	ENOG4107S6Z	Na H antiporter
HX109_RS09185	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HX109_RS09190	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HX109_RS09200	ENOG4105HA9	of methanol dehydrogenase type
HX109_RS09210	ENOG4108V0P	LemA family
HX109_RS09220	ENOG4105DR5	peptidase
HX109_RS09225	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HX109_RS09245	ENOG4105CRK	lysyL-tRNA synthetase
HX109_RS09250	ENOG4105VPI	YqaE family transport protein
HX109_RS09260	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HX109_RS09270	ENOG4105C27	TonB-dependent Receptor Plug
HX109_RS09285	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HX109_RS09310	ENOG41067HS	methyltransferase
HX109_RS09315	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
HX109_RS09320	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HX109_RS09330	ENOG4105D9N	nucleoside
HX109_RS09340	ENOG4105C10	Electron transfer flavoprotein
HX109_RS09345	ENOG4105BZJ	Electron transfer flavoprotein
HX109_RS09350	ENOG4105CPP	Dehydrogenase, E1 component
HX109_RS09360	ENOG4105F0N	pyrophosphate phospho-hydrolase
HX109_RS09365	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HX109_RS09370	ENOG4105VTW	prevent-host-death family
HX109_RS09375	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
HX109_RS09380	ENOG4105ZMH	deoxynucleoside kinase
HX109_RS09385	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HX109_RS09395	ENOG4105CFH	Aspartokinase
HX109_RS09400	ENOG4105C28	cystathionine
HX109_RS09410	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HX109_RS09415	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HX109_RS09420	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HX109_RS09425	ENOG4105CAY	ferredoxin--nadp reductase
HX109_RS09435	ENOG4105C3R	Methionine synthase
HX109_RS09440	ENOG4105C3R	Methionine synthase
HX109_RS09445	ENOG4105SYT	Methylenetetrahydrofolate reductase
HX109_RS09460	ENOG4105CEP	NADH dehydrogenase
HX109_RS09480	ENOG4107RH7	Nicotinate phosphoribosyltransferase
HX109_RS09485	ENOG4105CQC	Prephenate dehydratase
HX109_RS09490	ENOG4105CHM	Aminotransferase
HX109_RS09500	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
HX109_RS09505	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HX109_RS09510	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HX109_RS09530	ENOG4107S18	3-phosphoshikimate 1-carboxyvinyltransferase
HX109_RS09545	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HX109_RS09550	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HX109_RS09560	ENOG4105EMN	RNA polymerase sigma factor
HX109_RS09575	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HX109_RS09580	ENOG4107ZHV	Transcriptional regulator
HX109_RS09585	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
HX109_RS09605	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HX109_RS09615	ENOG4107YM1	mraZ protein
HX109_RS09620	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HX109_RS09630	ENOG4105CJN	penicillin-binding protein
HX109_RS09635	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HX109_RS09640	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HX109_RS09645	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HX109_RS09650	ENOG4105CNI	cell division protein FtsW
HX109_RS09655	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HX109_RS09660	ENOG4105DFU	Cell wall formation (By similarity)
HX109_RS09670	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HX109_RS09675	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HX109_RS09680	ENOG4105KTH	gatB Yqey
HX109_RS09695	ENOG41075H3	AraC family transcriptional regulator
HX109_RS09710	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HX109_RS09730	ENOG4107414	GntR family transcriptional regulator
HX109_RS09735	ENOG4105CGS	Alpha-glucosidase
HX109_RS09760	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HX109_RS09770	ENOG410667J	hydrolase
HX109_RS09775	ENOG41066YJ	Beta-lactamase
HX109_RS09795	ENOG4105EZV	Transcriptional regulator
HX109_RS09845	ENOG4105J7I	hydrolase
HX109_RS09850	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
HX109_RS09865	ENOG4105C12	Phosphoribosylglycinamide synthetase
HX109_RS09895	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HX109_RS09900	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HX109_RS09910	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HX109_RS09915	ENOG4105D2N	Aldolase
HX109_RS09925	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HX109_RS09935	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HX109_RS09940	ENOG4105C1A	potassium transporter peripheral membrane
HX109_RS09945	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HX109_RS09960	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HX109_RS09970	ENOG4105C26	Dehydrogenase
HX109_RS09975	ENOG4105NWN	ApaG protein
HX109_RS09990	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HX109_RS09995	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HX109_RS10000	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HX109_RS10005	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HX109_RS10010	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HX109_RS10015	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
HX109_RS10025	ENOG4105CJ2	(LipO)protein
HX109_RS10030	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HX109_RS10055	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
HX109_RS10060	ENOG4105FE9	pseudouridine synthase
HX109_RS10070	ENOG410830R	acetyltransferase
HX109_RS10075	ENOG4108Z1Z	gCN5-related N-acetyltransferase
HX109_RS10100	ENOG4105D44	asparaginase
HX109_RS10110	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
HX109_RS10125	ENOG4108R6W	Transcriptional regulator, ARAC family
HX109_RS10135	ENOG4105CMG	Carbohydrate kinase
HX109_RS10140	ENOG4105C93	Xylose Isomerase
HX109_RS10150	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
HX109_RS10155	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HX109_RS10160	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HX109_RS10165	ENOG4108YZG	isomerase
HX109_RS10175	ENOG4105E6M	Sulphatase-modifying factor protein
HX109_RS10185	ENOG4107QWR	cellulase (EC 3.2.1.4)
HX109_RS10190	ENOG4105CAK	Cell division ATP-binding protein ftsE
HX109_RS10220	ENOG4107QWK	SAICAR synthetase
HX109_RS10225	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HX109_RS10245	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HX109_RS10250	ENOG4107QQG	Dehydrogenase
HX109_RS10255	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HX109_RS10270	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HX109_RS10305	ENOG4105EEI	dihydropteroate synthase
HX109_RS10315	ENOG4105EWK	phytoene
HX109_RS10340	ENOG4105D7A	ATP-binding protein
HX109_RS10345	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HX109_RS10355	ENOG4107QZC	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HX109_RS10360	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HX109_RS10370	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HX109_RS10380	ENOG4105EHZ	conserved protein UCP016719
HX109_RS10395	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HX109_RS10400	ENOG4105EA8	2-Nitropropane dioxygenase
HX109_RS10405	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HX109_RS10420	ENOG4105VCQ	rubredoxin
HX109_RS10425	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HX109_RS10430	ENOG4107RNU	major facilitator superfamily MFS_1
HX109_RS10435	ENOG4105WH1	Two component transcriptional regulator luxr family
HX109_RS10440	ENOG4105BZU	Histidine kinase
HX109_RS10455	ENOG4107QZF	nitrite reductase NADPH large subunit
HX109_RS10500	ENOG4105HY2	Glycosidase related protein
HX109_RS10510	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
HX109_RS10540	ENOG4105CK5	oxidoreductase
HX109_RS10550	ENOG4105CHU	acetyl-coa acetyltransferase
HX109_RS10555	ENOG4105CTJ	Metal Dependent Phosphohydrolase
HX109_RS10580	ENOG4108UUM	single-stranded DNA-binding protein
HX109_RS10585	ENOG4105W5Q	DNA repair protein (RadC
HX109_RS10865	ENOG41067QW	Transcriptional regulator
HX109_RS10880	ENOG4106855	Competence protein
HX109_RS10890	ENOG4107QHF	type ii secretion system protein e
HX109_RS10990	ENOG4105D7Q	type ii secretion system
HX109_RS11050	ENOG4107WTH	Galactitol-1-phosphate dehydrogenase
HX109_RS11065	ENOG4105MVE	transcriptional regulator
HX109_RS11070	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HX109_RS11085	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HX109_RS11110	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HX109_RS11130	ENOG4105EMN	RNA polymerase sigma factor
HX109_RS11135	ENOG4105C8N	cysteinyl-tRNA synthetase
HX109_RS11140	ENOG4105EUJ	GTP cyclohydrolase i
HX109_RS11155	ENOG4105FFC	UPF0187 protein
HX109_RS11175	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HX109_RS11190	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
HX109_RS11195	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
HX109_RS11205	ENOG4105D3R	alkyl hydroperoxide reductase
HX109_RS11220	ENOG4108Z7R	Chaperone CsaA
HX109_RS11230	ENOG4105BZ1	(ABC) transporter
HX109_RS11240	ENOG4107R6T	Involved in the transcription termination process (By similarity)
HX109_RS11250	ENOG4105VIE	preprotein translocase, subunit YajC
HX109_RS11260	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HX109_RS11265	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HX109_RS11275	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
HX109_RS11305	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HX109_RS11310	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HX109_RS11335	ENOG4105D05	Receptor
HX109_RS11355	ENOG4105C3F	Signal peptidase i
HX109_RS11360	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HX109_RS11370	ENOG4105FA0	parb-like partition protein
HX109_RS11375	ENOG4107QJE	Chromosome Partitioning Protein
HX109_RS11380	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
HX109_RS11385	ENOG4105D5P	Methylmalonyl-coA mutase
HX109_RS11400	ENOG4105DBI	uridine monophosphokinase
HX109_RS11435	ENOG4105CJ1	ABC, transporter
HX109_RS11445	ENOG4105KWG	Pfam:DUF1696
HX109_RS11460	ENOG4108YZA	Nitrogen regulatory protein pii
HX109_RS11485	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HX109_RS11495	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HX109_RS11510	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HX109_RS11515	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HX109_RS11520	ENOG4108IUX	(ABC) transporter
HX109_RS11525	ENOG4105RHA	ABC transporter, permease
HX109_RS11530	ENOG4105EGS	Mechanosensitive ion channel
HX109_RS11545	ENOG4105BZ1	(ABC) transporter
HX109_RS11555	ENOG4105CKK	Glycosyl transferase, family 2
HX109_RS11565	ENOG41081WG	50s ribosomal protein l31
HX109_RS11575	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HX109_RS11595	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HX109_RS11600	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HX109_RS11610	ENOG4107RNH	Outer membrane receptor FepA
HX109_RS11615	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HX109_RS11660	ENOG4105DTQ	mandelate racemase muconate lactonizing
HX109_RS11695	ENOG4105DMW	Dehydrogenase reductase
HX109_RS11760	ENOG41061MV	Arylsulfatase
HX109_RS11780	ENOG4105ID8	Transcriptional regulator, ARAC family
HX109_RS11795	ENOG4105CWX	Alpha-1,2-mannosidase
HX109_RS11800	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HX109_RS11805	ENOG4105CXK	mandelate racemase muconate lactonizing
HX109_RS11820	ENOG4105DKQ	ROK family
HX109_RS11825	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HX109_RS11830	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
HX109_RS11845	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
HX109_RS11885	ENOG4108UJU	UPF0301 protein
HX109_RS11895	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HX109_RS11900	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HX109_RS11920	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HX109_RS11925	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HX109_RS11930	ENOG4105CXT	aspartate transcarbamylase
HX109_RS11940	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HX109_RS11945	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HX109_RS11950	ENOG4105K4I	Scp-like extracellular
HX109_RS11975	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HX109_RS11995	ENOG4108S4H	thioesterase Superfamily protein
HX109_RS12000	ENOG4105CGY	Dna recombination protein
HX109_RS12035	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
HX109_RS12045	ENOG4105CBG	Sulfatase
HX109_RS12055	ENOG4105E0A	ABC, transporter
HX109_RS12065	ENOG4105EHG	Permease protein
HX109_RS12075	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HX109_RS12085	ENOG4105GFR	rna polymerase sigma factor
HX109_RS12110	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HX109_RS12125	ENOG4108K8S	endonuclease I
HX109_RS12130	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HX109_RS12135	ENOG4105E2X	shikimate dehydrogenase
HX109_RS12155	ENOG4105C8Y	Acetylornithine aminotransferase
HX109_RS12165	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HX109_RS12170	ENOG41090R7	Ferric uptake
HX109_RS12185	ENOG4105D8V	Glucose sorbosone dehydrogenase
HX109_RS12190	ENOG4105F27	Major Facilitator
HX109_RS12200	ENOG4105DKW	ABC transporter
HX109_RS12235	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
HX109_RS12250	ENOG4105VDW	Csbd family
HX109_RS12260	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HX109_RS12275	ENOG4105VN1	Heat shock protein
HX109_RS12290	ENOG4105CJ1	ABC, transporter
HX109_RS12340	ENOG4105E2D	ec 3.2.1.52
HX109_RS12350	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HX109_RS12365	ENOG4108HRK	Histidine kinase
HX109_RS12370	ENOG4105DY9	regulatoR
HX109_RS12380	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HX109_RS12385	ENOG4105VRS	hydrolase family 18
HX109_RS12415	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HX109_RS12425	ENOG4105C26	Dehydrogenase
HX109_RS12430	ENOG4105C01	Dihydroxy-acid dehydratase
HX109_RS12435	ENOG4105C7K	acetolactate synthase
HX109_RS12440	ENOG4108ZP8	Acetolactate synthase small subunit
HX109_RS12445	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HX109_RS12450	ENOG4105C7B	Threonine dehydratase
HX109_RS12455	ENOG4105C26	Dehydrogenase
HX109_RS12475	ENOG4105IIU	Aminopeptidase
HX109_RS12490	ENOG4105UYK	outer membrane protein a
HX109_RS12520	ENOG4105C34	Pseudouridine synthase
HX109_RS12525	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HX109_RS12535	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HX109_RS12545	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
HX109_RS12550	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HX109_RS12555	ENOG4105VC4	domain protein
HX109_RS12605	ENOG4108IJ1	Dehydrogenase
HX109_RS12610	ENOG4107QQG	Dehydrogenase
HX109_RS12615	ENOG4105J5G	Transferase hexapeptide repeat containing protein
HX109_RS12620	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HX109_RS12625	ENOG4107R5Z	Oxidoreductase domain protein
HX109_RS12650	ENOG4105CK5	oxidoreductase
HX109_RS12685	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
HX109_RS12690	ENOG41080ET	plasmid maintenance system killer protein
HX109_RS12755	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
HX109_RS12760	ENOG41080ET	plasmid maintenance system killer protein
HX109_RS12770	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HX109_RS12775	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HX109_RS12780	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HX109_RS12785	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HX109_RS12795	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
HX109_RS12810	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HX109_RS12820	ENOG4105CGH	5'-nucleotidase
HX109_RS12825	ENOG4105CGH	5'-nucleotidase
HX109_RS12835	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HX109_RS12855	ENOG4107TCE	N-acetyltransferase
HX109_RS12860	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HX109_RS12870	ENOG41074B2	UPF0747 protein
HX109_RS12940	ENOG41061MV	Arylsulfatase
HX109_RS12955	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
HX109_RS12990	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HX109_RS13015	ENOG4105E0M	Sulfatase
HX109_RS13020	ENOG4105ETE	Transcriptional regulator (LacI family
HX109_RS13045	ENOG4107TYG	Oxidoreductase domain-containing protein
HX109_RS13050	ENOG4105C1G	acyl-Coa dehydrogenase
HX109_RS13110	ENOG4105E39	Enoyl-CoA hydratase
HX109_RS13115	ENOG4107R0K	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
HX109_RS13120	ENOG4105C26	Dehydrogenase
HX109_RS13125	ENOG4105CWX	Alpha-1,2-mannosidase
HX109_RS13140	ENOG4105CWX	Alpha-1,2-mannosidase
HX109_RS13155	ENOG4107TRN	Xylose isomerase domain protein TIM barrel
HX109_RS13185	ENOG4105CBG	Sulfatase
HX109_RS13190	ENOG4105D8V	Glucose sorbosone dehydrogenase
HX109_RS13215	ENOG4108RCM	Nitroreductase
HX109_RS13220	ENOG4105KVH	Transcriptional regulator
HX109_RS13225	ENOG4105DQ6	Transposase
HX109_RS13230	ENOG4105CMM	transposase
HX109_RS13255	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HX109_RS13260	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HX109_RS13275	ENOG4105CNU	cell division protein FtsK
HX109_RS13285	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HX109_RS13300	ENOG4105D3R	alkyl hydroperoxide reductase
HX109_RS13305	ENOG4105DFD	Na H antiporter
HX109_RS13310	ENOG4105C28	cystathionine
HX109_RS13315	ENOG4105J0Q	Transcriptional regulator
HX109_RS13320	ENOG4107QN2	dihydrolipoyl dehydrogenase
HX109_RS13330	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HX109_RS13345	ENOG4105CD3	dihydroorotase
HX109_RS13365	ENOG4105CA0	peroxidase
HX109_RS13375	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HX109_RS13390	ENOG4105D7W	serine acetyltransferase
HX109_RS13395	ENOG4105D3Q	Sugar transferase
HX109_RS13435	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HX109_RS13445	ENOG4105CFG	Acts as a chaperone (By similarity)
HX109_RS13450	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HX109_RS13460	ENOG4105KA0	thioesterase Superfamily protein
HX109_RS13470	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
HX109_RS13480	ENOG4105QNR	S1 RNA binding domain protein
HX109_RS13495	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HX109_RS13500	ENOG41074H6	response regulator
HX109_RS13505	ENOG41080WS	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HX109_RS13525	ENOG4105E1F	short-chain dehydrogenase reductase
HX109_RS13530	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HX109_RS13595	ENOG4105CSM	endonuclease III
HX109_RS13600	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HX109_RS13635	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HX109_RS13645	ENOG4105DU1	integral membrane protein, terc
HX109_RS13650	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HX109_RS13665	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
HX109_RS13670	ENOG4105DF5	DNA topoisomerase IV, subunit A
HX109_RS13695	ENOG4108VVK	transcriptional Regulator, AsnC
HX109_RS13700	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HX109_RS13725	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HX109_RS13735	ENOG4105C5H	ABC transporter
HX109_RS13750	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HX109_RS13755	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HX109_RS13760	ENOG4107U9T	Pfam:Ribonuclease_BN
HX109_RS13770	ENOG4105D29	Helix-turn-helix type 11 domain protein
HX109_RS13790	ENOG4108V06	Glutathione peroxidase
HX109_RS13795	ENOG4105CZ9	Domain of unknown function (DU1801)
HX109_RS13810	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HX109_RS13815	ENOG4108ZAF	Molybdopterin
HX109_RS13820	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
HX109_RS13830	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HX109_RS13860	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HX109_RS13885	ENOG4105S64	Formate nitrite transporter
HX109_RS13900	ENOG4108TM9	integral membrane protein
HX109_RS13905	ENOG4105VPI	YqaE family transport protein
HX109_RS13920	ENOG4105K63	Thioredoxin
HX109_RS13935	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HX109_RS13940	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HX109_RS13945	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HX109_RS13950	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
HX109_RS13955	ENOG41065KQ	synthase
HX109_RS13965	ENOG4108IYU	L-aspartate oxidase
HX109_RS13975	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HX109_RS14000	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
HX109_RS14005	ENOG4107QKZ	Ompa motb domain protein
HX109_RS14015	ENOG4105CPP	Dehydrogenase, E1 component
HX109_RS14045	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HX109_RS14050	ENOG4105C98	muts2 protein
HX109_RS14080	ENOG4105D6J	arsenicaL-resistance protein
HX109_RS14100	ENOG41081QV	Universal stress protein
HX109_RS14135	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HX109_RS14140	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HX109_RS14150	ENOG4105CQB	FAD linked oxidase domain protein
HX109_RS14160	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HX109_RS14165	ENOG4105C0B	DNA polymerase III (alpha subunit)
HX109_RS14170	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HX109_RS14175	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HX109_RS14185	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HX109_RS14190	ENOG4108JQ1	Dehydrogenase
HX109_RS14220	ENOG4105D1S	lipid A biosynthesis
HX109_RS14225	ENOG4105CAT	Cytidine monophosphate kinase
HX109_RS14230	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HX109_RS14245	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HX109_RS14265	ENOG4105CBC	glutamate synthase
HX109_RS14290	ENOG4108Z03	MAF-like protein
HX109_RS14310	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
HX109_RS14335	ENOG4105C9A	Phoh family
HX109_RS14355	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HX109_RS14365	ENOG4105D64	Mechanosensitive ion channel
HX109_RS14370	ENOG4108RMU	ferritin dps family protein
HX109_RS14375	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HX109_RS14415	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HX109_RS14430	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HX109_RS14480	ENOG4105CDH	Citrulline--aspartate ligase
HX109_RS14485	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HX109_RS14495	ENOG4105C8Y	Acetylornithine aminotransferase
HX109_RS14505	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HX109_RS14520	ENOG4107T6X	nag kinase
HX109_RS14530	ENOG4105CH7	arginosuccinase
HX109_RS14550	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HX109_RS14560	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HX109_RS14570	ENOG4105DFA	alanine racemase domain protein
HX109_RS14580	ENOG4105EYW	Ion transport protein
HX109_RS14585	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HX109_RS14610	ENOG4105C3G	gtp-binding protein
HX109_RS14615	ENOG4108JYZ	YitT family
HX109_RS14620	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
HX109_RS14635	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
HX109_RS14640	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HX109_RS14645	ENOG4108JQC	penicillin-binding protein 1A
HX109_RS14650	ENOG4105CUY	Mechanosensitive ion channel
HX109_RS14685	ENOG4105D7W	serine acetyltransferase
HX109_RS14690	ENOG4105C6T	cysteine synthase
HX109_RS14700	ENOG4105D7N	magnesium and cobalt transport protein CorA
HX109_RS14705	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HX109_RS14710	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HX109_RS14715	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HX109_RS14720	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HX109_RS14725	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HX109_RS14730	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HX109_RS14735	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HX109_RS14740	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HX109_RS14745	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HX109_RS14765	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HX109_RS14775	ENOG4105CHR	reductase
HX109_RS14785	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HX109_RS14795	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HX109_RS14800	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HX109_RS14805	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HX109_RS14810	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HX109_RS14815	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HX109_RS14820	ENOG4105DCI	Phosphohydrolase
HX109_RS14885	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
HX109_RS14895	ENOG4105D75	Capsular exopolysaccharide family
HX109_RS14910	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HX109_RS14915	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HX109_RS14930	ENOG4105K64	Glycosyl transferase, family 2
HX109_RS14940	ENOG4105K64	Glycosyl transferase, family 2
HX109_RS14955	ENOG4107QRS	glycosyltransferase group 2 family protein
HX109_RS14970	ENOG4108IJF	Heavy metal efflux pump, CzcA
HX109_RS14985	ENOG4108M4U	conserved membrane protein
HX109_RS14990	ENOG4105C59	p-type ATPase
HX109_RS15005	ENOG4105D49	3-dehydroquinate synthase
HX109_RS15030	ENOG4107RKG	DJ-1/PfpI family
HX109_RS15045	ENOG4105CPP	Dehydrogenase, E1 component
HX109_RS15055	ENOG4105CP7	Triose-phosphate isomerase
HX109_RS15060	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HX109_RS15075	ENOG4107TPS	domain protein
HX109_RS15080	ENOG4108VCT	Sulfite exporter TauE/SafE
HX109_RS15095	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
HX109_RS15160	ENOG4107XVH	Transcriptional regulator
HX109_RS15175	ENOG410900G	Protein of unknown function (DUF421)
HX109_RS15205	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HX109_RS15275	ENOG4105C3M	thioredoxin reductase
HX109_RS15460	ENOG4105CAR	Terminase, large subunit
HX109_RS15475	ENOG4105CDU	Replicative dna helicase
HX109_RS15490	ENOG4106GRJ	chromatin binding
HX109_RS15550	ENOG4105FJR	Lmbe family
HX109_RS15555	ENOG4105C28	cystathionine
HX109_RS15565	ENOG4105CRE	cytochrome C
HX109_RS15610	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HX109_RS15620	ENOG4105C26	Dehydrogenase
HX109_RS15640	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HX109_RS15645	ENOG4105C5H	ABC transporter
HX109_RS15655	ENOG4107QX3	carboxylase
HX109_RS15660	ENOG4105C5I	Dehydrogenase
HX109_RS15675	ENOG4105DTQ	mandelate racemase muconate lactonizing
HX109_RS15680	ENOG4107W2A	UPF0173 metal-dependent hydrolase
HX109_RS15715	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
HX109_RS15720	ENOG4105K89	arsenate reductase
HX109_RS15735	ENOG4105C9Q	fumarate hydratase class II
HX109_RS15750	ENOG4105SFS	phosphoesterase RecJ domain protein
HX109_RS15760	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
HX109_RS15765	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HX109_RS15770	ENOG4105HMI	Membrane
HX109_RS15775	ENOG4105DUM	transcriptional regulator, lysR family
HX109_RS15785	ENOG4105DY8	decarboxylase
HX109_RS15790	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HX109_RS15795	ENOG4105KZX	Pterin carbinolamine dehydratase
HX109_RS15800	ENOG4105CDY	transcriptional regulatory protein
HX109_RS15810	ENOG4107RJC	Iron-containing alcohol dehydrogenase
HX109_RS15820	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HX109_RS15830	ENOG4105C7H	Helicase, RecD TraA family
HX109_RS15845	ENOG4106H78	methyltransferase
HX109_RS15870	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HX109_RS15875	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HX109_RS15880	ENOG4105VRT	cytoplasmic protein
HX109_RS15900	ENOG4107QKV	phosphomannomutase
HX109_RS15910	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HX109_RS15920	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HX109_RS15925	ENOG4108URH	decarboxylase
HX109_RS15930	ENOG4105WH1	Two component transcriptional regulator luxr family
HX109_RS15935	ENOG4105BZU	Histidine kinase
HX109_RS15970	ENOG4107R7A	Allophanate hydrolase subunit 2
HX109_RS15975	ENOG4105P4J	Allophanate hydrolase, subunit 1
HX109_RS15985	ENOG4105C0P	Mg chelatase subunit ChlI
HX109_RS16005	ENOG4107ZQV	short-chain dehydrogenase reductase
HX109_RS16010	ENOG4105EJQ	L-serine dehydratase
HX109_RS16015	ENOG410662T	chitinase
HX109_RS16020	ENOG4105C1J	atp-dependent rna helicase
HX109_RS16070	ENOG4105D05	Receptor
HX109_RS16080	ENOG4105EUJ	GTP cyclohydrolase i
HX109_RS16090	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
HX109_RS16095	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HX109_RS16100	ENOG4105C6K	Malic enzyme
HX109_RS16105	ENOG4105CI2	imidazolone-5-propionate hydrolase
HX109_RS16130	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HX109_RS16135	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
HX109_RS16140	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HX109_RS16170	ENOG4107KJX	Transcriptional regulator
HX109_RS16185	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
HX109_RS16190	ENOG4105D2H	Uronic isomerase
HX109_RS16205	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HX109_RS16210	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
HX109_RS16215	ENOG4105CG6	trap dicarboxylate transporter dctm subunit