locus-tag	class	description
UMN179_RS00040	COG1940	carbohydrate kinase activity
UMN179_RS00045	COG0673	inositol 2-dehydrogenase activity
UMN179_RS00055	COG0307	riboflavin synthase, alpha
UMN179_RS00065	COG2801	Transposase and inactivated derivatives
UMN179_RS00090	COG0134	indole-3-glycerol-phosphate synthase activity
UMN179_RS00090	COG0135	phosphoribosylanthranilate isomerase activity
UMN179_RS00095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
UMN179_RS00100	COG0512	Glutamine amidotransferase of anthranilate synthase
UMN179_RS00105	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
UMN179_RS00110	COG0301	tRNA thio-modification
UMN179_RS00110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
UMN179_RS00115	COG1722	exodeoxyribonuclease VII activity
UMN179_RS00120	COG0142	geranyltranstransferase activity
UMN179_RS00140	COG0469	pyruvate kinase activity
UMN179_RS00145	COG2062	phosphohistidine phosphatase, SixA
UMN179_RS00150	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
UMN179_RS00155	COG0024	Methionine aminopeptidase
UMN179_RS00160	COG0316	Belongs to the HesB IscA family
UMN179_RS00170	COG0814	amino acid
UMN179_RS00175	COG1760	l-serine dehydratase
UMN179_RS00185	COG0440	acetolactate synthase activity
UMN179_RS00190	COG0028	Belongs to the TPP enzyme family
UMN179_RS00195	COG1757	Na H antiporter
UMN179_RS00205	COG0297	glycogen (starch) synthase activity
UMN179_RS00215	COG1523	belongs to the glycosyl hydrolase 13 family
UMN179_RS00220	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
UMN179_RS00225	COG1335	isochorismatase
UMN179_RS00235	COG2840	Smr protein MutS2
UMN179_RS00245	COG0402	S-adenosylhomocysteine deaminase activity
UMN179_RS00250	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
UMN179_RS00255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
UMN179_RS00260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
UMN179_RS00265	COG1074	ATP-dependent DNA helicase activity
UMN179_RS00270	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
UMN179_RS00275	COG2252	PERMEase
UMN179_RS00280	COG3593	DNA synthesis involved in DNA repair
UMN179_RS00285	COG2431	L-lysine efflux transmembrane transporter activity
UMN179_RS00290	COG1280	lysine exporter protein (LysE YggA)
UMN179_RS00295	COG0628	permease
UMN179_RS00300	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
UMN179_RS00315	COG2358	TRAP transporter, solute receptor (TAXI family
UMN179_RS00325	COG3098	single-species biofilm formation
UMN179_RS00330	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
UMN179_RS00340	COG1611	Belongs to the LOG family
UMN179_RS00345	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
UMN179_RS00350	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
UMN179_RS00350	COG2885	chlorophyll binding
UMN179_RS00360	COG0277	FAD linked oxidase domain protein
UMN179_RS00360	COG0247	lactate metabolic process
UMN179_RS00380	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
UMN179_RS00385	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
UMN179_RS00390	COG2249	NAD(P)H dehydrogenase (quinone) activity
UMN179_RS00395	COG1846	Transcriptional regulator
UMN179_RS00400	COG1566	PFAM secretion protein HlyD family protein
UMN179_RS00405	COG2814	Major facilitator Superfamily
UMN179_RS00415	COG0500	methyltransferase
UMN179_RS00425	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
UMN179_RS00435	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
UMN179_RS00440	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
UMN179_RS00450	COG1286	toxin biosynthetic process
UMN179_RS00460	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
UMN179_RS00475	COG1704	LemA family
UMN179_RS00480	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
UMN179_RS00485	COG2823	Periplasmic or secreted lipoprotein
UMN179_RS00490	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
UMN179_RS00495	COG0792	nuclease activity
UMN179_RS00525	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
UMN179_RS00530	COG0517	IMP dehydrogenase activity
UMN179_RS00530	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
UMN179_RS00535	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
UMN179_RS00540	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
UMN179_RS00545	COG0328	RNA-DNA hybrid ribonuclease activity
UMN179_RS00555	COG0826	peptidase U32
UMN179_RS00575	COG0659	secondary active sulfate transmembrane transporter activity
UMN179_RS00580	COG1454	alcohol dehydrogenase
UMN179_RS00585	COG0583	DNA-binding transcription factor activity
UMN179_RS00595	COG0791	NLP P60 protein
UMN179_RS00605	COG3381	protein complex oligomerization
UMN179_RS00610	COG1114	Component of the transport system for branched-chain amino acids
UMN179_RS00615	COG1022	Amp-dependent synthetase and ligase
UMN179_RS00620	COG4608	Belongs to the ABC transporter superfamily
UMN179_RS00630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
UMN179_RS00635	COG0601	transmembrane transport
UMN179_RS00660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
UMN179_RS00665	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
UMN179_RS00670	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
UMN179_RS00675	COG1280	lysine exporter protein (LysE YggA)
UMN179_RS00685	COG1434	Gram-negative-bacterium-type cell wall biogenesis
UMN179_RS00690	COG0616	signal peptide processing
UMN179_RS00695	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
UMN179_RS00705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UMN179_RS00710	COG0577	efflux transmembrane transporter activity
UMN179_RS00710	COG1136	(ABC) transporter
UMN179_RS00715	COG1538	Outer membrane efflux protein
UMN179_RS00720	COG1278	Cold shock
UMN179_RS00725	COG2925	Exonuclease
UMN179_RS00735	COG3842	ATPase activity
UMN179_RS00740	COG1176	ABC-type spermidine putrescine transport system, permease component I
UMN179_RS00745	COG1177	transmembrane transport
UMN179_RS00785	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
UMN179_RS00810	COG2249	NAD(P)H dehydrogenase (quinone) activity
UMN179_RS00815	COG0583	DNA-binding transcription factor activity
UMN179_RS00825	COG0656	L-ascorbic acid biosynthetic process
UMN179_RS00830	COG0583	DNA-binding transcription factor activity
UMN179_RS00840	COG1560	Kdo2-lipid A biosynthetic process
UMN179_RS00845	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
UMN179_RS00845	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
UMN179_RS00850	COG0708	Exodeoxyribonuclease III
UMN179_RS00855	COG1946	Acyl-CoA thioesterase
UMN179_RS00860	COG0058	SHG alpha-glucan phosphorylase activity
UMN179_RS00865	COG0285	dihydrofolate synthase activity
UMN179_RS00870	COG0697	spore germination
UMN179_RS00880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UMN179_RS00885	COG0616	signal peptide processing
UMN179_RS00890	COG0778	Nitroreductase
UMN179_RS00895	COG0287	Prephenate dehydrogenase
UMN179_RS00895	COG1605	Chorismate mutase
UMN179_RS00900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
UMN179_RS00905	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
UMN179_RS00915	COG0582	viral genome integration into host DNA
UMN179_RS00920	COG3328	transposase activity
UMN179_RS00980	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
UMN179_RS01060	COG5301	cellulose 1,4-beta-cellobiosidase activity
UMN179_RS01090	COG0675	Transposase, IS605 OrfB family
UMN179_RS01185	COG4695	Portal protein
UMN179_RS01190	COG0582	viral genome integration into host DNA
UMN179_RS01205	COG1368	sulfuric ester hydrolase activity
UMN179_RS01210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
UMN179_RS01215	COG3108	Peptidase M15
UMN179_RS01220	COG2989	Protein conserved in bacteria
UMN179_RS01225	COG0793	Belongs to the peptidase S41A family
UMN179_RS01235	COG2995	paraquat-inducible protein a
UMN179_RS01240	COG3008	intermembrane lipid transfer
UMN179_RS01245	COG0488	(ABC) transporter
UMN179_RS01250	COG4607	ABC-type enterochelin transport system periplasmic component
UMN179_RS01255	COG4604	ABC transporter, ATP-binding protein
UMN179_RS01260	COG4605	iron ion homeostasis
UMN179_RS01265	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UMN179_RS01270	COG0725	ABC transporter, periplasmic molybdate-binding protein
UMN179_RS01275	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
UMN179_RS01280	COG4149	molybdate abc transporter
UMN179_RS01285	COG0842	Transport permease protein
UMN179_RS01290	COG1131	(ABC) transporter
UMN179_RS01295	COG0288	reversible hydration of carbon dioxide
UMN179_RS01300	COG3101	peptidyl-lysine hydroxylation
UMN179_RS01330	COG0494	nUDIX hydrolase
UMN179_RS01350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
UMN179_RS01360	COG1438	arginine binding
UMN179_RS01365	COG1090	epimerase
UMN179_RS01370	COG1944	ATP diphosphatase activity
UMN179_RS01375	COG0714	Associated with various cellular activities
UMN179_RS01385	COG1289	transmembrane transporter activity
UMN179_RS01390	COG3304	Inner membrane component domain
UMN179_RS01405	COG1254	Belongs to the acylphosphatase family
UMN179_RS01410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
UMN179_RS01415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
UMN179_RS01420	COG1121	(ABC) transporter
UMN179_RS01425	COG0803	Belongs to the bacterial solute-binding protein 9 family
UMN179_RS01430	COG2920	part of a sulfur-relay system
UMN179_RS01435	COG0670	Belongs to the BI1 family
UMN179_RS01445	COG2951	lytic endotransglycosylase activity
UMN179_RS01470	COG3100	YcgL domain-containing protein
UMN179_RS01480	COG1368	sulfuric ester hydrolase activity
UMN179_RS01490	COG1216	Glycosyl transferase, family 2
UMN179_RS01495	COG0438	transferase activity, transferring glycosyl groups
UMN179_RS01505	COG1216	Glycosyl transferase, family 2
UMN179_RS01510	COG5039	Polysaccharide pyruvyl transferase
UMN179_RS01535	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
UMN179_RS01540	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
UMN179_RS01540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
UMN179_RS01545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
UMN179_RS01835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
UMN179_RS01875	COG0305	Participates in initiation and elongation during chromosome replication
UMN179_RS01890	COG2707	UPF0756 membrane protein
UMN179_RS01895	COG0583	DNA-binding transcription factor activity
UMN179_RS01905	COG1530	ribonuclease E activity
UMN179_RS01930	COG0815	Transfers the fatty acyl group on membrane lipoproteins
UMN179_RS01935	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
UMN179_RS01940	COG0045	succinate-CoA ligase (ADP-forming) activity
UMN179_RS01945	COG0508	dehydrogenase complex catalyzes the overall conversion of
UMN179_RS01950	COG0567	Dehydrogenase, E1 component
UMN179_RS01955	COG0372	Belongs to the citrate synthase family
UMN179_RS01960	COG1309	transcriptional regulator
UMN179_RS01965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UMN179_RS01970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
UMN179_RS01975	COG1077	Cell shape determining protein MreB Mrl
UMN179_RS01980	COG1792	Involved in formation and maintenance of cell shape
UMN179_RS01985	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
UMN179_RS02000	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
UMN179_RS02010	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
UMN179_RS02020	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
UMN179_RS02040	COG0861	Integral membrane protein TerC family
UMN179_RS02050	COG2831	hemolysin activation secretion protein
UMN179_RS02055	COG3210	domain, Protein
UMN179_RS02090	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
UMN179_RS02100	COG2814	Major facilitator Superfamily
UMN179_RS02105	COG0563	adenylate kinase activity
UMN179_RS02185	COG3063	Type IV pilus biogenesis stability protein PilW
UMN179_RS02190	COG1426	Protein conserved in bacteria
UMN179_RS02200	COG0124	histidyl-tRNA synthetase
UMN179_RS02205	COG2976	Protein conserved in bacteria
UMN179_RS02215	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
UMN179_RS02220	COG0291	Belongs to the bacterial ribosomal protein bL35 family
UMN179_RS02230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
UMN179_RS02240	COG1862	Preprotein translocase
UMN179_RS02245	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
UMN179_RS02250	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
UMN179_RS02255	COG1522	sequence-specific DNA binding
UMN179_RS02280	COG2315	Protein conserved in bacteria
UMN179_RS02295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
UMN179_RS02300	COG1840	ABC-type Fe3 transport system, periplasmic component
UMN179_RS02305	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
UMN179_RS02310	COG3842	ATPase activity
UMN179_RS02320	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
UMN179_RS02325	COG0849	cell division
UMN179_RS02330	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
UMN179_RS02340	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
UMN179_RS02355	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
UMN179_RS02365	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
UMN179_RS02375	COG0768	penicillin binding
UMN179_RS02380	COG3116	cell division
UMN179_RS02385	COG0275	rRNA processing
UMN179_RS02390	COG2001	Belongs to the MraZ family
UMN179_RS02395	COG1802	Transcriptional regulator
UMN179_RS02400	COG1063	alcohol dehydrogenase
UMN179_RS02405	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
UMN179_RS02415	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
UMN179_RS02415	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
UMN179_RS02425	COG2721	sulfolactate sulfo-lyase activity
UMN179_RS02430	COG0187	DNA topoisomerase II activity
UMN179_RS02450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
UMN179_RS02455	COG0762	integral membrane protein
UMN179_RS02490	COG0084	hydrolase, TatD family'
UMN179_RS02495	COG0470	DNA polymerase III
UMN179_RS02500	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
UMN179_RS02505	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
UMN179_RS02510	COG0626	cystathionine gamma-synthase activity
UMN179_RS02550	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
UMN179_RS02555	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
UMN179_RS02570	COG0745	RESPONSE REGULATOR receiver
UMN179_RS02590	COG0538	isocitrate dehydrogenase activity
UMN179_RS02605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
UMN179_RS02615	COG2828	Protein conserved in bacteria
UMN179_RS02620	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
UMN179_RS02625	COG0372	Belongs to the citrate synthase family
UMN179_RS02630	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
UMN179_RS02640	COG0753	catalase activity
UMN179_RS02645	COG0493	'glutamate synthase
UMN179_RS02650	COG0070	glutamate synthase
UMN179_RS02650	COG0067	glutamate synthase
UMN179_RS02650	COG0069	glutamate synthase activity
UMN179_RS02655	COG0673	inositol 2-dehydrogenase activity
UMN179_RS02665	COG1175	transmembrane transport
UMN179_RS02670	COG1653	transport
UMN179_RS02675	COG3842	ATPase activity
UMN179_RS02680	COG2186	Transcriptional regulator
UMN179_RS02685	COG0673	inositol 2-dehydrogenase activity
UMN179_RS02690	COG1858	cytochrome C peroxidase
UMN179_RS02695	COG0471	metal ion transport
UMN179_RS02700	COG2990	Protein conserved in bacteria
UMN179_RS02705	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
UMN179_RS02705	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
UMN179_RS02715	COG0720	synthase
UMN179_RS02720	COG0602	queuosine metabolic process
UMN179_RS02730	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
UMN179_RS02735	COG4137	Cytochrome C assembly protein
UMN179_RS02740	COG4536	flavin adenine dinucleotide binding
UMN179_RS02745	COG2801	Transposase and inactivated derivatives
UMN179_RS02760	COG1476	TRANSCRIPTIONal
UMN179_RS02765	COG2801	Transposase and inactivated derivatives
UMN179_RS02770	COG2963	transposase activity
UMN179_RS02775	COG0783	Belongs to the Dps family
UMN179_RS02780	COG0512	Glutamine amidotransferase of anthranilate synthase
UMN179_RS02790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
UMN179_RS02795	COG1620	l-lactate permease
UMN179_RS02800	COG0247	lactate metabolic process
UMN179_RS02805	COG1139	Iron-sulfur cluster binding protein
UMN179_RS02810	COG1556	Lactate utilization protein
UMN179_RS02815	COG1070	Carbohydrate kinase
UMN179_RS02825	COG4213	ABC transporter substrate-binding protein
UMN179_RS02830	COG1129	ABC transporter
UMN179_RS02835	COG4214	carbohydrate transport
UMN179_RS02850	COG0741	lytic transglycosylase activity
UMN179_RS02860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
UMN179_RS02870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
UMN179_RS02875	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
UMN179_RS02890	COG1534	Rna-binding protein
UMN179_RS02895	COG0778	Nitroreductase
UMN179_RS02955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UMN179_RS02960	COG0737	Belongs to the 5'-nucleotidase family
UMN179_RS02965	COG0561	phosphatase activity
UMN179_RS02970	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
UMN179_RS02985	COG0280	phosphate acetyltransferase
UMN179_RS02985	COG0281	malic enzyme
UMN179_RS02990	COG1187	pseudouridine synthase activity
UMN179_RS02995	COG2814	Major facilitator Superfamily
UMN179_RS03015	COG0484	heat shock protein binding
UMN179_RS03020	COG0443	Heat shock 70 kDa protein
UMN179_RS03030	COG5339	Protein conserved in bacteria
UMN179_RS03045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
UMN179_RS03055	COG1959	2 iron, 2 sulfur cluster binding
UMN179_RS03060	COG0366	Alpha amylase catalytic
UMN179_RS03075	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
UMN179_RS03080	COG0204	Acyl-transferase
UMN179_RS03085	COG2132	Multicopper oxidase
UMN179_RS03090	COG0789	Transcriptional regulator
UMN179_RS03095	COG2217	Heavy metal translocating P-type atpase
UMN179_RS03100	COG2217	Heavy metal translocating P-type atpase
UMN179_RS03110	COG0675	Transposase, IS605 OrfB family
UMN179_RS03120	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
UMN179_RS03125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
UMN179_RS03130	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
UMN179_RS03140	COG3077	Addiction module antitoxin, RelB DinJ family
UMN179_RS03145	COG2610	gluconate transmembrane transporter activity
UMN179_RS03150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
UMN179_RS03155	COG3622	Belongs to the hyi family
UMN179_RS03160	COG0235	Class ii aldolase
UMN179_RS03165	COG3395	kinase activity
UMN179_RS03170	COG2084	Dehydrogenase
UMN179_RS03175	COG1349	DNA-binding transcription factor activity
UMN179_RS03200	COG0330	HflC and HflK could
UMN179_RS03205	COG0330	HflC and HflK could
UMN179_RS03215	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
UMN179_RS03220	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
UMN179_RS03225	COG0778	Nitroreductase
UMN179_RS03235	COG2833	Protein of unknown function (DUF455)
UMN179_RS03245	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
UMN179_RS03250	COG0732	type I restriction modification DNA specificity domain
UMN179_RS03270	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
UMN179_RS03300	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
UMN179_RS03305	COG2011	ABC-type metal ion transport system permease component
UMN179_RS03310	COG1464	Belongs to the NlpA lipoprotein family
UMN179_RS03315	COG1956	GAF domain-containing protein
UMN179_RS03320	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
UMN179_RS03325	COG0583	DNA-binding transcription factor activity
UMN179_RS03330	COG1309	transcriptional regulator
UMN179_RS03335	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
UMN179_RS03340	COG0322	excinuclease ABC activity
UMN179_RS03350	COG2835	tetraacyldisaccharide 4'-kinase activity
UMN179_RS03360	COG1132	(ABC) transporter
UMN179_RS03365	COG2333	competence protein COMEC
UMN179_RS03365	COG0658	competence protein
UMN179_RS03375	COG0617	tRNA 3'-terminal CCA addition
UMN179_RS03380	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
UMN179_RS03390	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
UMN179_RS03400	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
UMN179_RS03415	COG1444	tRNA N-acetyltransferase activity
UMN179_RS03420	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
UMN179_RS03425	COG1702	phosphate starvation-inducible protein PhoH
UMN179_RS03430	COG2918	glutathione biosynthetic process
UMN179_RS03430	COG1181	Belongs to the D-alanine--D-alanine ligase family
UMN179_RS03440	COG1385	rRNA (uridine-N3-)-methyltransferase activity
UMN179_RS03445	COG1678	Uncharacterized ACR, COG1678
UMN179_RS03455	COG4160	amino acid transport
UMN179_RS03460	COG4215	(ABC) transporter
UMN179_RS03465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UMN179_RS03470	COG1126	abc transporter atp-binding protein
UMN179_RS03490	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
UMN179_RS03500	COG0138	bifunctional purine biosynthesis protein purh
UMN179_RS03505	COG3105	Protein conserved in bacteria
UMN179_RS03525	COG0305	Participates in initiation and elongation during chromosome replication
UMN179_RS03535	COG0583	DNA-binding transcription factor activity
UMN179_RS03540	COG2363	Small membrane protein
UMN179_RS03545	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
UMN179_RS03555	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
UMN179_RS03560	COG1349	DNA-binding transcription factor activity
UMN179_RS03565	COG5295	Hep Hag repeat protein
UMN179_RS03570	COG0633	Ferredoxin
UMN179_RS03575	COG0515	serine threonine protein kinase
UMN179_RS03590	COG1940	carbohydrate kinase activity
UMN179_RS03605	COG1393	Belongs to the ArsC family
UMN179_RS03610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
UMN179_RS03615	COG1876	peptidase activity
UMN179_RS03620	COG3021	interspecies interaction between organisms
UMN179_RS03635	COG0539	negative regulation of cytoplasmic translation
UMN179_RS03640	COG0776	regulation of translation
UMN179_RS03645	COG2364	Membrane
UMN179_RS03665	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
UMN179_RS03670	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
UMN179_RS03675	COG0284	orotidine-5'-phosphate decarboxylase activity
UMN179_RS03680	COG0023	Translation Initiation Factor
UMN179_RS03685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
UMN179_RS03690	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
UMN179_RS03700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
UMN179_RS03710	COG0747	negative chemotaxis
UMN179_RS03715	COG0601	transmembrane transport
UMN179_RS03720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
UMN179_RS03725	COG0444	Belongs to the ABC transporter superfamily
UMN179_RS03730	COG4608	Belongs to the ABC transporter superfamily
UMN179_RS03745	COG0129	dihydroxy-acid dehydratase activity
UMN179_RS03750	COG3265	gluconokinase activity
UMN179_RS03775	COG4224	UPF0291 protein
UMN179_RS03780	COG1733	regulation of RNA biosynthetic process
UMN179_RS03810	COG1482	cell wall glycoprotein biosynthetic process
UMN179_RS03820	COG3716	PTS system mannose fructose sorbose family IID component
UMN179_RS03825	COG3715	PTS system
UMN179_RS03830	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
UMN179_RS03830	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
UMN179_RS03835	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
UMN179_RS03845	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
UMN179_RS03850	COG1053	succinate dehydrogenase
UMN179_RS03865	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
UMN179_RS03880	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
UMN179_RS03885	COG5002	protein histidine kinase activity
UMN179_RS03885	COG2198	Histidine kinase
UMN179_RS03885	COG0784	Response regulator, receiver
UMN179_RS03890	COG2267	carboxylic ester hydrolase activity
UMN179_RS03900	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
UMN179_RS03905	COG0675	Transposase, IS605 OrfB family
UMN179_RS03935	COG2852	Protein conserved in bacteria
UMN179_RS03940	COG4804	nuclease activity
UMN179_RS03945	COG4545	Glutaredoxin-related protein
UMN179_RS03960	COG0363	glucosamine-6-phosphate deaminase activity
UMN179_RS03965	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
UMN179_RS03995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
UMN179_RS04000	COG3038	cytochrome b561
UMN179_RS04010	COG0740	serine-type endopeptidase activity
UMN179_RS04015	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
UMN179_RS04025	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
UMN179_RS04030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
UMN179_RS04030	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
UMN179_RS04035	COG1105	Belongs to the carbohydrate kinase PfkB family
UMN179_RS04040	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
UMN179_RS04040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
UMN179_RS04040	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
UMN179_RS04045	COG0583	DNA-binding transcription factor activity
UMN179_RS04050	COG2259	Doxx family
UMN179_RS04065	COG0675	Transposase, IS605 OrfB family
UMN179_RS04070	COG0668	transmembrane transport
UMN179_RS04080	COG0367	asparagine synthase
UMN179_RS04085	COG0675	Transposase, IS605 OrfB family
UMN179_RS04120	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
UMN179_RS04160	COG4245	von Willebrand factor, type A
UMN179_RS04170	COG4245	von Willebrand factor, type A
UMN179_RS04185	COG0459	protein refolding
UMN179_RS04190	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
UMN179_RS04195	COG1027	Aspartate ammonia-lyase
UMN179_RS04200	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
UMN179_RS04200	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
UMN179_RS04205	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
UMN179_RS04210	COG1522	sequence-specific DNA binding
UMN179_RS04215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
UMN179_RS04220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
UMN179_RS04225	COG0006	proline dipeptidase activity
UMN179_RS04235	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
UMN179_RS04240	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
UMN179_RS04245	COG1530	ribonuclease E activity
UMN179_RS04255	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
UMN179_RS04260	COG0592	DNA-directed DNA polymerase activity
UMN179_RS04265	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
UMN179_RS04270	COG0230	Belongs to the bacterial ribosomal protein bL34 family
UMN179_RS04275	COG0594	ribonuclease P activity
UMN179_RS04290	COG1115	amino acid carrier protein
UMN179_RS04295	COG0527	aspartate kinase activity
UMN179_RS04295	COG0460	homoserine dehydrogenase
UMN179_RS04335	COG2841	Protein conserved in bacteria
UMN179_RS04340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
UMN179_RS04345	COG1280	lysine exporter protein (LysE YggA)
UMN179_RS04350	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
UMN179_RS04360	COG2860	membrane
UMN179_RS04365	COG3097	Belongs to the UPF0267 family
UMN179_RS04370	COG1793	dna ligase
UMN179_RS04385	COG2116	formate transmembrane transporter activity
UMN179_RS04395	COG2853	Lipoprotein
UMN179_RS04425	COG2252	PERMEase
UMN179_RS04430	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
UMN179_RS04435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
UMN179_RS04460	COG3068	Protein conserved in bacteria
UMN179_RS04465	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
UMN179_RS04470	COG2816	NAD+ diphosphatase activity
UMN179_RS04480	COG3070	regulator of competence-specific genes
UMN179_RS04485	COG2369	cell adhesion
UMN179_RS04490	COG5005	Phage virion morphogenesis
UMN179_RS04520	COG3161	chorismate lyase activity
UMN179_RS04525	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
UMN179_RS04530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
UMN179_RS04545	COG2095	MarC family integral membrane protein
UMN179_RS04550	COG0488	(ABC) transporter
UMN179_RS04570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
UMN179_RS04580	COG0246	Mannitol dehydrogenase
UMN179_RS04590	COG0583	DNA-binding transcription factor activity
UMN179_RS04600	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
UMN179_RS04605	COG0672	)-iron permease
UMN179_RS04610	COG2837	iron assimilation
UMN179_RS04615	COG2822	iron ion transport
UMN179_RS04635	COG0210	DNA helicase
UMN179_RS04640	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
UMN179_RS04650	COG0049	tRNA binding
UMN179_RS04660	COG2168	tRNA wobble position uridine thiolation
UMN179_RS04665	COG2923	Belongs to the DsrF TusC family
UMN179_RS04670	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
UMN179_RS04675	COG2964	Protein conserved in bacteria
UMN179_RS04680	COG0545	Peptidyl-prolyl cis-trans isomerase
UMN179_RS04685	COG2900	Belongs to the SlyX family
UMN179_RS04695	COG3956	TIGRFAM MazG family protein
UMN179_RS04700	COG1132	(ABC) transporter
UMN179_RS04705	COG2194	sulfuric ester hydrolase activity
UMN179_RS04710	COG3119	arylsulfatase activity
UMN179_RS04715	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
UMN179_RS04720	COG0641	radical SAM
UMN179_RS04725	COG0730	response to heat
UMN179_RS04730	COG1940	carbohydrate kinase activity
UMN179_RS04735	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
UMN179_RS04740	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
UMN179_RS04745	COG1253	flavin adenine dinucleotide binding
UMN179_RS04755	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
UMN179_RS04760	COG1575	Belongs to the MenA family. Type 1 subfamily
UMN179_RS04765	COG1720	tRNA m6t6A37 methyltransferase activity
UMN179_RS04770	COG2226	methyltransferase
UMN179_RS04785	COG1309	transcriptional regulator
UMN179_RS04795	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
UMN179_RS04810	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
UMN179_RS04830	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
UMN179_RS04865	COG2183	response to ionizing radiation
UMN179_RS04875	COG2814	Major facilitator Superfamily
UMN179_RS04905	COG0545	Peptidyl-prolyl cis-trans isomerase
UMN179_RS04910	COG0688	phosphatidylethanolamine metabolic process
UMN179_RS04915	COG1399	metal-binding, possibly nucleic acid-binding protein
UMN179_RS04920	COG0333	Belongs to the bacterial ribosomal protein bL32 family
UMN179_RS04925	COG0416	fatty acid biosynthetic process
UMN179_RS04930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
UMN179_RS04935	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
UMN179_RS04940	COG1028	Short-chain dehydrogenase reductase Sdr
UMN179_RS04950	COG2962	Rard protein
UMN179_RS04955	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
UMN179_RS04975	COG0142	geranyltranstransferase activity
UMN179_RS04980	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
UMN179_RS04990	COG1322	Protein conserved in bacteria
UMN179_RS04995	COG0424	maF-like protein
UMN179_RS05025	COG0557	exoribonuclease II activity
UMN179_RS05030	COG1045	serine acetyltransferase
UMN179_RS05035	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
UMN179_RS05040	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
UMN179_RS05045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
UMN179_RS05050	COG0588	phosphoglycerate mutase activity
UMN179_RS05055	COG4942	peptidase
UMN179_RS05060	COG2861	carbohydrate metabolic process
UMN179_RS05065	COG0729	surface antigen
UMN179_RS05070	COG2911	Protein conserved in bacteria
UMN179_RS05105	COG4795	General secretion pathway protein
UMN179_RS05115	COG2969	positive regulation of protein catabolic process
UMN179_RS05125	COG3283	Transcriptional regulator of aromatic amino acids metabolism
UMN179_RS05130	COG1011	Hydrolase
UMN179_RS05140	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
UMN179_RS05145	COG2137	regulation of response to DNA damage stimulus
UMN179_RS05165	COG0251	oxidation-reduction process
UMN179_RS05170	COG1979	alcohol dehydrogenase
UMN179_RS05190	COG0786	glutamate:sodium symporter activity
UMN179_RS05215	COG1230	cation diffusion facilitator family transporter
UMN179_RS05225	COG1122	ATPase activity
UMN179_RS05230	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
UMN179_RS05245	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
UMN179_RS05260	COG0656	L-ascorbic acid biosynthetic process
UMN179_RS05270	COG2272	Belongs to the type-B carboxylesterase lipase family
UMN179_RS05410	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
UMN179_RS05460	COG0675	Transposase, IS605 OrfB family
UMN179_RS05465	COG0210	DNA helicase
UMN179_RS05470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
UMN179_RS05495	COG0745	RESPONSE REGULATOR receiver
UMN179_RS05500	COG5002	protein histidine kinase activity
UMN179_RS05505	COG0564	pseudouridine synthase activity
UMN179_RS05515	COG3201	nicotinamide mononucleotide transporter
UMN179_RS05555	COG0733	neurotransmitter:sodium symporter activity
UMN179_RS05565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
UMN179_RS05570	COG1621	beta-fructofuranosidase activity
UMN179_RS05590	COG2991	Protein conserved in bacteria
UMN179_RS05595	COG1477	protein flavinylation
UMN179_RS05605	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
UMN179_RS05610	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
UMN179_RS05615	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
UMN179_RS05625	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
UMN179_RS05630	COG0271	Belongs to the BolA IbaG family
UMN179_RS05635	COG3056	Lipoprotein
UMN179_RS05640	COG0800	Aldolase
UMN179_RS05650	COG4178	(ABC) transporter
UMN179_RS05655	COG1737	Transcriptional regulator
UMN179_RS05660	COG1879	ABC-type sugar transport system periplasmic component
UMN179_RS05665	COG1129	ABC transporter
UMN179_RS05670	COG1172	Belongs to the binding-protein-dependent transport system permease family
UMN179_RS05675	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
UMN179_RS05680	COG1940	carbohydrate kinase activity
UMN179_RS05685	COG0698	ribose 5-phosphate isomerase
UMN179_RS05690	COG2502	aspartate--ammonia ligase
UMN179_RS05695	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
UMN179_RS05700	COG0126	phosphoglycerate kinase activity
UMN179_RS05705	COG0191	fructose-bisphosphate aldolase activity
UMN179_RS05720	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
UMN179_RS05725	COG0203	ribosomal protein L17
UMN179_RS05730	COG0202	RNA polymerase activity
UMN179_RS05735	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
UMN179_RS05740	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
UMN179_RS05755	COG0201	protein transport
UMN179_RS05765	COG1841	ribosomal large subunit assembly
UMN179_RS05780	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
UMN179_RS05785	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
UMN179_RS05790	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
UMN179_RS05795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
UMN179_RS05820	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
UMN179_RS05830	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
UMN179_RS05835	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
UMN179_RS05840	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
UMN179_RS05850	COG0088	Forms part of the polypeptide exit tunnel
UMN179_RS05860	COG0051	transcription antitermination factor activity, RNA binding
UMN179_RS05870	COG1012	belongs to the aldehyde dehydrogenase family
UMN179_RS05880	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
UMN179_RS05885	COG1414	Transcriptional regulator
UMN179_RS05930	COG0681	Belongs to the peptidase S26 family
UMN179_RS05935	COG0481	GTPase activity
UMN179_RS05945	COG0316	Belongs to the HesB IscA family
UMN179_RS05945	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
UMN179_RS05950	COG1040	competence protein
UMN179_RS05955	COG0561	phosphatase activity
UMN179_RS05960	COG3958	Transketolase
UMN179_RS05970	COG3037	sugar-specific permease SgaT UlaA
UMN179_RS05980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
UMN179_RS05985	COG1609	Transcriptional regulator
UMN179_RS05990	COG0604	alcohol dehydrogenase
UMN179_RS05995	COG0742	ribosomal rna small subunit methyltransferase
UMN179_RS06000	COG0552	protein localization to endoplasmic reticulum
UMN179_RS06005	COG2884	Cell division ATP-binding protein ftsE
UMN179_RS06010	COG2177	Part of the ABC transporter FtsEX involved in
UMN179_RS06020	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
UMN179_RS06020	COG2221	Nitrite and sulphite reductase 4Fe-4S
UMN179_RS06025	COG3381	protein complex oligomerization
UMN179_RS06030	COG3302	dmso reductase anchor subunit
UMN179_RS06035	COG0437	4 iron, 4 sulfur cluster binding
UMN179_RS06040	COG0243	molybdopterin cofactor binding
UMN179_RS06095	COG0357	Ribosomal RNA small subunit methyltransferase G
UMN179_RS06115	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
UMN179_RS06130	COG1388	LysM domain
UMN179_RS06130	COG4942	peptidase
UMN179_RS06135	COG1238	metal cluster binding
UMN179_RS06145	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
UMN179_RS06165	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
UMN179_RS06170	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
UMN179_RS06170	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
UMN179_RS06175	COG0569	domain protein
UMN179_RS06180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
UMN179_RS06195	COG1921	L-seryl-tRNASec selenium transferase activity
UMN179_RS06200	COG3276	selenocysteine insertion sequence binding
UMN179_RS06210	COG2274	protein secretion by the type I secretion system
UMN179_RS06225	COG3676	manually curated
UMN179_RS06230	COG0758	DNA mediated transformation
UMN179_RS06245	COG1349	DNA-binding transcription factor activity
UMN179_RS06250	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
UMN179_RS06255	COG1070	Carbohydrate kinase
UMN179_RS06265	COG0235	Class ii aldolase
UMN179_RS06270	COG0738	Major facilitator superfamily
UMN179_RS06275	COG3850	Histidine kinase
UMN179_RS06280	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
UMN179_RS06285	COG3062	negative regulation of establishment of protein localization
UMN179_RS06295	COG0437	4 iron, 4 sulfur cluster binding
UMN179_RS06300	COG0348	domain, Protein
UMN179_RS06305	COG3043	anaerobic respiration
UMN179_RS06310	COG3005	denitrification pathway
UMN179_RS06315	COG0165	Argininosuccinate lyase
UMN179_RS06335	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
UMN179_RS06350	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
UMN179_RS06400	COG1840	ABC-type Fe3 transport system, periplasmic component
UMN179_RS06405	COG4771	TonB-dependent receptor
UMN179_RS06415	COG0675	Transposase, IS605 OrfB family
UMN179_RS06420	COG0748	coenzyme F420 binding
UMN179_RS06425	COG2129	metallophosphoesterase
UMN179_RS06430	COG3172	ATPase kinase involved in NAD metabolism
UMN179_RS06435	COG2960	long-chain fatty acid transporting porin activity
UMN179_RS06465	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
UMN179_RS06495	COG1194	a g-specific adenine glycosylase
UMN179_RS06500	COG0220	tRNA (guanine-N7-)-methyltransferase activity
UMN179_RS06505	COG3171	Protein conserved in bacteria
UMN179_RS06510	COG0218	Necessary for normal cell division and for the maintenance of normal septation
UMN179_RS06540	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
UMN179_RS06545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
UMN179_RS06555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
UMN179_RS06595	COG2132	Multicopper oxidase
UMN179_RS06600	COG2801	Transposase and inactivated derivatives
UMN179_RS06605	COG2963	transposase activity
UMN179_RS06620	COG2217	Heavy metal translocating P-type atpase
UMN179_RS06630	COG0789	Transcriptional regulator
UMN179_RS06640	COG2801	Transposase and inactivated derivatives
UMN179_RS06660	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
UMN179_RS06690	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
UMN179_RS06715	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
UMN179_RS06720	COG2249	NAD(P)H dehydrogenase (quinone) activity
UMN179_RS06725	COG2267	carboxylic ester hydrolase activity
UMN179_RS06735	COG0705	Rhomboid family
UMN179_RS06740	COG1349	DNA-binding transcription factor activity
UMN179_RS06760	COG1739	Uncharacterized protein family UPF0029
UMN179_RS06775	COG0728	peptidoglycan biosynthetic process
UMN179_RS06780	COG0196	riboflavin kinase activity
UMN179_RS06790	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
UMN179_RS06800	COG1263	PTS System
UMN179_RS06800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
UMN179_RS06810	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
UMN179_RS06815	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
UMN179_RS06825	COG1381	Involved in DNA repair and RecF pathway recombination
UMN179_RS06830	COG0675	Transposase, IS605 OrfB family
UMN179_RS06845	COG0606	chelatase, subunit chli
UMN179_RS06855	COG0321	lipoyl(octanoyl) transferase activity
UMN179_RS06860	COG2921	Belongs to the UPF0250 family
UMN179_RS06865	COG1686	Belongs to the peptidase S11 family
UMN179_RS06875	COG0772	Belongs to the SEDS family
UMN179_RS06880	COG0768	penicillin binding
UMN179_RS06890	COG0799	negative regulation of ribosome biogenesis
UMN179_RS06905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
UMN179_RS06910	COG1151	hydroxylamine reductase activity
UMN179_RS06920	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
UMN179_RS06925	COG2814	Major facilitator Superfamily
UMN179_RS06930	COG2966	Psort location CytoplasmicMembrane, score
UMN179_RS06935	COG3610	response to peptide
UMN179_RS06940	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
UMN179_RS06950	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
UMN179_RS06975	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
UMN179_RS06985	COG1494	fructose-1,6-bisphosphatase
UMN179_RS06990	COG3074	FtsZ-dependent cytokinesis
UMN179_RS06995	COG3468	outer membrane autotransporter barrel domain protein
UMN179_RS07015	COG0504	CTP synthase activity
UMN179_RS07020	COG0390	transport system, permease component
UMN179_RS07025	COG1126	abc transporter atp-binding protein
UMN179_RS07040	COG0471	metal ion transport
UMN179_RS07045	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
UMN179_RS07050	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
UMN179_RS07055	COG0247	lactate metabolic process
UMN179_RS07085	COG1605	Chorismate mutase
UMN179_RS07085	COG0077	Prephenate dehydratase
UMN179_RS07090	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
UMN179_RS07100	COG0561	phosphatase activity
UMN179_RS07110	COG3978	acetolactate synthase activity
UMN179_RS07115	COG0129	dihydroxy-acid dehydratase activity
UMN179_RS07125	COG1012	belongs to the aldehyde dehydrogenase family
UMN179_RS07125	COG1454	alcohol dehydrogenase
UMN179_RS07135	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
UMN179_RS07140	COG0551	DNA topoisomerase type I activity
UMN179_RS07155	COG1741	Belongs to the pirin family
UMN179_RS07160	COG0675	Transposase, IS605 OrfB family
UMN179_RS07165	COG1741	Belongs to the pirin family
UMN179_RS07190	COG1169	isochorismate synthase
UMN179_RS07195	COG0436	Aminotransferase
UMN179_RS07200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
UMN179_RS07215	COG0227	Belongs to the bacterial ribosomal protein bL28 family
UMN179_RS07225	COG0697	spore germination
UMN179_RS07230	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
UMN179_RS07235	COG2814	Major facilitator Superfamily
UMN179_RS07245	COG2974	May be involved in recombination
UMN179_RS07255	COG4785	May be involved in cell division
UMN179_RS07260	COG0513	Belongs to the DEAD box helicase family
UMN179_RS07265	COG0354	folic acid binding
UMN179_RS07270	COG1561	YicC-like family, N-terminal region
UMN179_RS07275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
UMN179_RS07280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
UMN179_RS07285	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
UMN179_RS07290	COG0587	DNA-directed DNA polymerase activity
UMN179_RS07295	COG5007	Belongs to the BolA IbaG family
UMN179_RS07300	COG3113	response to antibiotic
UMN179_RS07305	COG2854	intermembrane phospholipid transfer
UMN179_RS07310	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
UMN179_RS07315	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
UMN179_RS07320	COG1127	ABC transporter
UMN179_RS07325	COG3117	lipopolysaccharide transmembrane transporter activity
UMN179_RS07330	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
UMN179_RS07335	COG1137	ATPase activity
UMN179_RS07340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
UMN179_RS07345	COG1660	Displays ATPase and GTPase activities
UMN179_RS07355	COG0590	tRNA wobble adenosine to inosine editing
UMN179_RS07360	COG0121	glutamine amidotransferase
UMN179_RS07375	COG0823	Involved in the tonB-independent uptake of proteins
UMN179_RS07385	COG3718	enzyme involved in inositol metabolism
UMN179_RS07400	COG4178	(ABC) transporter
UMN179_RS07430	COG0439	Biotin carboxylase
UMN179_RS07435	COG0511	ligase activity, forming carbon-carbon bonds
UMN179_RS07445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
UMN179_RS07460	COG0183	Belongs to the thiolase family
UMN179_RS07465	COG1250	3-hydroxyacyl-CoA dehydrogenase
UMN179_RS07465	COG1024	Enoyl-CoA hydratase
UMN179_RS07475	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
UMN179_RS07480	COG0494	nUDIX hydrolase
UMN179_RS07495	COG0495	leucyl-tRNA aminoacylation
UMN179_RS07500	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
UMN179_RS07505	COG1466	dna polymerase III delta subunit
UMN179_RS07510	COG0494	nUDIX hydrolase
UMN179_RS07530	COG0338	D12 class N6 adenine-specific DNA methyltransferase
UMN179_RS07535	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
UMN179_RS07545	COG4796	Type ii and iii secretion system protein
UMN179_RS07565	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
UMN179_RS07570	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
UMN179_RS07575	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
UMN179_RS07610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
UMN179_RS07625	COG0859	PFAM glycosyl transferase family 9
UMN179_RS07640	COG1519	Transferase
UMN179_RS07645	COG0463	Glycosyl transferase, family 2
UMN179_RS07650	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
UMN179_RS07655	COG1509	lysine 2,3-aminomutase activity
UMN179_RS07660	COG3061	Opacity-associated protein A
UMN179_RS07660	COG3266	domain, Protein
UMN179_RS07665	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
UMN179_RS07670	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
UMN179_RS07675	COG0742	ribosomal rna small subunit methyltransferase
UMN179_RS07680	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
UMN179_RS07700	COG1854	S-ribosylhomocysteine lyase activity
UMN179_RS07725	COG1172	Belongs to the binding-protein-dependent transport system permease family
UMN179_RS07730	COG1879	ABC-type sugar transport system periplasmic component
UMN179_RS07735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
UMN179_RS07745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
UMN179_RS07780	COG0019	diaminopimelate decarboxylase activity
UMN179_RS07810	COG3924	membrane
UMN179_RS07815	COG4145	pantothenate transmembrane transporter activity
UMN179_RS07820	COG2264	protein methyltransferase activity
UMN179_RS07825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UMN179_RS07840	COG3732	PTS system glucitol sorbitol-specific
UMN179_RS07850	COG1028	Short-chain dehydrogenase reductase Sdr
UMN179_RS07855	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
UMN179_RS07860	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
UMN179_RS07865	COG1349	DNA-binding transcription factor activity
UMN179_RS07880	COG0335	large ribosomal subunit rRNA binding
UMN179_RS07890	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
UMN179_RS07895	COG0228	four-way junction DNA binding
UMN179_RS07925	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
UMN179_RS07945	COG0163	prenyltransferase activity
UMN179_RS07965	COG1210	Utp--glucose-1-phosphate uridylyltransferase
UMN179_RS07970	COG2271	Major facilitator Superfamily
UMN179_RS07975	COG0584	glycerophosphoryl diester phosphodiesterase
UMN179_RS07980	COG1555	photosystem II stabilization
UMN179_RS07995	COG3250	beta-galactosidase activity
UMN179_RS08015	COG0765	amino acid transport
UMN179_RS08020	COG1126	abc transporter atp-binding protein
UMN179_RS08065	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
UMN179_RS08080	COG3423	Transcriptional regulator
UMN179_RS08085	COG2801	Transposase and inactivated derivatives
UMN179_RS08095	COG2842	Transposition protein
UMN179_RS08105	COG4396	Host-nuclease inhibitor protein Gam
UMN179_RS08115	COG4382	Mu-like prophage protein Gp16
UMN179_RS08130	COG3023	N-Acetylmuramoyl-L-alanine amidase
UMN179_RS08155	COG0640	Transcriptional regulator
UMN179_RS08295	COG4974	Belongs to the 'phage' integrase family
UMN179_RS08310	COG3392	D12 class N6 adenine-specific DNA methyltransferase
UMN179_RS08330	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
UMN179_RS08335	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
UMN179_RS08340	COG0363	glucosamine-6-phosphate deaminase activity
UMN179_RS08345	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
UMN179_RS08350	COG1218	3'(2'),5'-bisphosphate nucleotidase
UMN179_RS08355	COG0494	nUDIX hydrolase
UMN179_RS08360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
UMN179_RS08380	COG3026	antisigma factor binding
UMN179_RS08385	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
UMN179_RS08390	COG1595	DNA-templated transcription, initiation
UMN179_RS08405	COG3256	nitric oxide reductase
UMN179_RS08410	COG0842	Transport permease protein
UMN179_RS08415	COG0842	Transport permease protein
UMN179_RS08420	COG1131	(ABC) transporter
UMN179_RS08425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UMN179_RS08435	COG0513	Belongs to the DEAD box helicase family
UMN179_RS08460	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
UMN179_RS08480	COG0733	neurotransmitter:sodium symporter activity
UMN179_RS08485	COG0402	S-adenosylhomocysteine deaminase activity
UMN179_RS08495	COG2271	Major facilitator Superfamily
UMN179_RS08500	COG0483	inositol monophosphate 1-phosphatase activity
UMN179_RS08505	COG0673	inositol 2-dehydrogenase activity
UMN179_RS08515	COG3962	Belongs to the TPP enzyme family
UMN179_RS08520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
UMN179_RS08545	COG1609	Transcriptional regulator
UMN179_RS08550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
UMN179_RS08560	COG0339	signal peptide processing
UMN179_RS08565	COG1115	amino acid carrier protein
UMN179_RS08570	COG2205	protein histidine kinase activity
UMN179_RS08575	COG0745	RESPONSE REGULATOR receiver
UMN179_RS08580	COG0450	alkyl hydroperoxide reductase
UMN179_RS08585	COG0626	cystathionine gamma-synthase activity
UMN179_RS08590	COG4235	cytochrome complex assembly
UMN179_RS08595	COG4235	cytochrome complex assembly
UMN179_RS08595	COG3088	subunit of a heme lyase
UMN179_RS08605	COG1138	Cytochrome C-type biogenesis protein
UMN179_RS08610	COG3301	Polysulphide reductase, NrfD
UMN179_RS08615	COG0437	4 iron, 4 sulfur cluster binding
UMN179_RS08620	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
UMN179_RS08630	COG2207	Transcriptional regulator
UMN179_RS08630	COG1609	Transcriptional regulator
UMN179_RS08640	COG2850	peptidyl-arginine hydroxylation
UMN179_RS08645	COG2914	Belongs to the UPF0125 (RnfH) family
UMN179_RS08650	COG2867	negative regulation of translational initiation
UMN179_RS08655	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
UMN179_RS08655	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
UMN179_RS08660	COG0193	aminoacyl-tRNA hydrolase activity
UMN179_RS08665	COG0012	GTP binding
UMN179_RS08680	COG3133	Outer membrane lipoprotein
UMN179_RS08685	COG3102	Protein conserved in bacteria
UMN179_RS08700	COG0733	neurotransmitter:sodium symporter activity
UMN179_RS08705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
UMN179_RS08720	COG4658	electron transport chain
UMN179_RS08735	COG4657	Part of a membrane complex involved in electron transport
UMN179_RS08740	COG2949	membrane
UMN179_RS08750	COG0730	response to heat
UMN179_RS08770	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
UMN179_RS08775	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
UMN179_RS08780	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
UMN179_RS08790	COG1138	Cytochrome C-type biogenesis protein
UMN179_RS08810	COG1763	Mo-molybdopterin cofactor biosynthetic process
UMN179_RS08815	COG2814	Major facilitator Superfamily
UMN179_RS08820	COG0747	negative chemotaxis
UMN179_RS08825	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
UMN179_RS08835	COG2226	methyltransferase
UMN179_RS08840	COG0814	amino acid
UMN179_RS08845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
UMN179_RS08855	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
UMN179_RS08860	COG0813	purine-nucleoside phosphorylase activity
UMN179_RS08865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
UMN179_RS08870	COG0076	glutamate decarboxylase activity
UMN179_RS08890	COG3084	Protein conserved in bacteria
UMN179_RS08895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
UMN179_RS08900	COG3085	chromosome segregation
UMN179_RS08915	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
UMN179_RS08930	COG1349	DNA-binding transcription factor activity
UMN179_RS08945	COG1028	Short-chain dehydrogenase reductase Sdr
UMN179_RS08955	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
UMN179_RS08970	COG2186	Transcriptional regulator
UMN179_RS08980	COG2994	toxin metabolic process
UMN179_RS08985	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
UMN179_RS08995	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
UMN179_RS09000	COG1959	2 iron, 2 sulfur cluster binding
UMN179_RS09010	COG0822	iron-sulfur transferase activity
UMN179_RS09020	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
UMN179_RS09025	COG0443	Heat shock 70 kDa protein
UMN179_RS09030	COG0633	Ferredoxin
UMN179_RS09035	COG2975	iron-sulfur cluster assembly
UMN179_RS09040	COG3119	arylsulfatase activity
UMN179_RS09060	COG1609	Transcriptional regulator
UMN179_RS09065	COG1217	gtp-binding protein TYPA
UMN179_RS09070	COG0174	glutamine synthetase
UMN179_RS09075	COG2999	glutathione oxidoreductase activity
UMN179_RS09085	COG0131	Imidazoleglycerol-phosphate dehydratase
UMN179_RS09085	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
UMN179_RS09090	COG4804	nuclease activity
UMN179_RS09100	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
UMN179_RS09105	COG0107	imidazoleglycerol-phosphate synthase activity
UMN179_RS09120	COG0351	phosphomethylpyrimidine kinase
UMN179_RS09130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
UMN179_RS09135	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
UMN179_RS09140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
UMN179_RS09145	COG1116	anion transmembrane transporter activity
UMN179_RS09160	COG0038	chloride channel
UMN179_RS09170	COG3023	N-Acetylmuramoyl-L-alanine amidase
UMN179_RS09175	COG4969	Belongs to the N-Me-Phe pilin family
UMN179_RS09180	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
UMN179_RS09185	COG1459	type II secretion system
UMN179_RS09190	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
UMN179_RS09195	COG0675	Transposase, IS605 OrfB family
UMN179_RS09200	COG0237	dephospho-CoA kinase activity
UMN179_RS09200	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
UMN179_RS09235	COG2864	formate dehydrogenase
UMN179_RS09240	COG0437	4 iron, 4 sulfur cluster binding
UMN179_RS09245	COG0243	molybdopterin cofactor binding
UMN179_RS09245	COG3383	formate dehydrogenase (NAD+) activity
UMN179_RS09250	COG0243	molybdopterin cofactor binding
UMN179_RS09250	COG3383	formate dehydrogenase (NAD+) activity
UMN179_RS09255	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
UMN179_RS09260	COG0561	phosphatase activity
UMN179_RS09265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UMN179_RS09270	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
UMN179_RS09295	COG1607	acyl-coa hydrolase
UMN179_RS09300	COG2350	Protein conserved in bacteria
UMN179_RS09305	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
UMN179_RS09310	COG1011	Hydrolase
UMN179_RS09375	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
UMN179_RS09385	COG4991	sh3 domain protein
UMN179_RS09390	COG0306	phosphate transporter
UMN179_RS09395	COG1392	Phosphate transport regulator
UMN179_RS09400	COG3025	triphosphatase activity
UMN179_RS09405	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
UMN179_RS09410	COG0052	Belongs to the universal ribosomal protein uS2 family
UMN179_RS09420	COG0528	UMP kinase activity
UMN179_RS09440	COG0575	Belongs to the CDS family
UMN179_RS09455	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
UMN179_RS09470	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
UMN179_RS09485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
UMN179_RS09490	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
UMN179_RS09495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
UMN179_RS09520	COG0460	homoserine dehydrogenase
UMN179_RS09520	COG0527	aspartate kinase activity
UMN179_RS09530	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
UMN179_RS09555	COG2017	converts alpha-aldose to the beta-anomer
UMN179_RS09565	COG1085	galactose-1-phosphate uridylyltransferase
UMN179_RS09570	COG1609	Transcriptional regulator
UMN179_RS09575	COG1879	ABC-type sugar transport system periplasmic component
UMN179_RS09580	COG1129	ABC transporter
UMN179_RS09585	COG4211	Belongs to the binding-protein-dependent transport system permease family
UMN179_RS09620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UMN179_RS09625	COG1126	abc transporter atp-binding protein
UMN179_RS09630	COG0765	amino acid transport
UMN179_RS09635	COG0765	amino acid transport
UMN179_RS09640	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
UMN179_RS09645	COG1882	Formate acetyltransferase
UMN179_RS09650	COG2116	formate transmembrane transporter activity
UMN179_RS09655	COG0537	adenosine 5'-monophosphoramidase activity
UMN179_RS09670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
UMN179_RS09720	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
UMN179_RS09730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
UMN179_RS09735	COG0859	PFAM glycosyl transferase family 9
UMN179_RS09740	COG1408	metallophosphoesterase
UMN179_RS09745	COG2081	HI0933 family
UMN179_RS09760	COG3083	sulfuric ester hydrolase activity
UMN179_RS09770	COG3081	Nucleoid-associated protein
UMN179_RS09775	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
UMN179_RS09780	COG0254	rRNA binding
UMN179_RS09785	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
UMN179_RS09790	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
UMN179_RS09795	COG3835	regulator
UMN179_RS09800	COG2610	gluconate transmembrane transporter activity
UMN179_RS09805	COG1929	Belongs to the glycerate kinase type-1 family
UMN179_RS09810	COG0405	Gamma-glutamyltransferase
UMN179_RS09840	COG0640	Transcriptional regulator
UMN179_RS09860	COG0583	DNA-binding transcription factor activity
UMN179_RS09870	COG0405	Gamma-glutamyltransferase
UMN179_RS09875	COG1923	regulation of RNA biosynthetic process
UMN179_RS09890	COG0860	N-Acetylmuramoyl-L-alanine amidase
UMN179_RS09890	COG1388	LysM domain
UMN179_RS09895	COG0802	atpase or kinase
UMN179_RS09900	COG0583	DNA-binding transcription factor activity
UMN179_RS09905	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
UMN179_RS09910	COG5383	Protein conserved in bacteria
UMN179_RS09915	COG1012	belongs to the aldehyde dehydrogenase family
UMN179_RS09920	COG1757	Na H antiporter
UMN179_RS09925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
UMN179_RS09935	COG1584	GPR1 FUN34 yaaH family protein
UMN179_RS09940	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
UMN179_RS09950	COG3630	sodium ion export across plasma membrane
UMN179_RS09955	COG1914	H( )-stimulated, divalent metal cation uptake system
UMN179_RS09960	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
UMN179_RS09965	COG1984	allophanate hydrolase subunit 2
UMN179_RS09970	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
UMN179_RS09975	COG0675	Transposase, IS605 OrfB family
UMN179_RS09995	COG1162	GTPase activity
UMN179_RS10000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
UMN179_RS10005	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
UMN179_RS10010	COG2190	(PTS) system
UMN179_RS10015	COG0277	FAD linked oxidase domain protein
UMN179_RS10020	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
UMN179_RS10020	COG1328	CTP reductase activity
UMN179_RS10025	COG0602	queuosine metabolic process
UMN179_RS10030	COG1966	Carbon starvation protein
UMN179_RS10035	COG3094	Invasion gene expression up-regulator, SirB
UMN179_RS10040	COG0084	hydrolase, TatD family'
UMN179_RS10045	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
UMN179_RS10065	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
UMN179_RS10080	COG0521	Mo-molybdopterin cofactor biosynthetic process
UMN179_RS10085	COG0735	belongs to the Fur family
UMN179_RS10090	COG0716	FMN binding
UMN179_RS10100	COG0596	Alpha beta hydrolase
UMN179_RS10105	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
UMN179_RS10110	COG0318	PFAM AMP-dependent synthetase and ligase
UMN179_RS10115	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
UMN179_RS10115	COG3264	Mechanosensitive ion channel
UMN179_RS10120	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
UMN179_RS10125	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
UMN179_RS10130	COG0730	response to heat
UMN179_RS10135	COG1560	Kdo2-lipid A biosynthetic process
UMN179_RS10145	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
UMN179_RS10160	COG2927	DNA polymerase III (CHI subunit)
UMN179_RS10165	COG2153	protein acetylation
UMN179_RS10200	COG1496	oxidoreductase activity
UMN179_RS10205	COG0564	pseudouridine synthase activity
UMN179_RS10215	COG4166	transmembrane transport
UMN179_RS10220	COG2095	MarC family integral membrane protein
UMN179_RS10225	COG0251	oxidation-reduction process
UMN179_RS10235	COG0187	DNA topoisomerase II activity
UMN179_RS10240	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
UMN179_RS10250	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
UMN179_RS10255	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
UMN179_RS10260	COG1845	cytochrome c oxidase, subunit III
UMN179_RS10265	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
UMN179_RS10275	COG2814	Major facilitator Superfamily
UMN179_RS10285	COG1271	oxidase subunit
UMN179_RS10290	COG1294	oxidase, subunit
UMN179_RS10300	COG0824	Thioesterase
UMN179_RS10305	COG0811	peptide transport
UMN179_RS10310	COG0848	biopolymer transport protein
UMN179_RS10315	COG3064	Membrane
UMN179_RS10330	COG0425	Belongs to the sulfur carrier protein TusA family
UMN179_RS10340	COG0346	lactoylglutathione lyase activity
UMN179_RS10365	COG2926	Belongs to the UPF0265 family
UMN179_RS10375	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
UMN179_RS10380	COG1393	Belongs to the ArsC family
UMN179_RS10385	COG3036	rescue of stalled ribosome
UMN179_RS10390	COG1305	Transglutaminase-like
UMN179_RS10400	COG2608	mercury ion transmembrane transporter activity
UMN179_RS10405	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
UMN179_RS10410	COG0303	'Molybdopterin
UMN179_RS10420	COG0330	HflC and HflK could
UMN179_RS10440	COG3022	response to hydroperoxide
UMN179_RS10460	COG0642	Histidine kinase
UMN179_RS10470	COG2194	sulfuric ester hydrolase activity
UMN179_RS10485	COG2195	Cleaves the N-terminal amino acid of tripeptides
UMN179_RS10505	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
UMN179_RS10510	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
UMN179_RS10515	COG0805	protein transport
UMN179_RS10525	COG1573	uracil-dna glycosylase
UMN179_RS10530	COG3700	Belongs to the class B bacterial acid phosphatase family
UMN179_RS10535	COG3842	ATPase activity
UMN179_RS10545	COG1840	ABC-type Fe3 transport system, periplasmic component
UMN179_RS10550	COG1902	pentaerythritol trinitrate reductase activity
UMN179_RS10555	COG2056	Na+-H+ antiporter family
UMN179_RS10560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
UMN179_RS10565	COG0346	lactoylglutathione lyase activity
UMN179_RS10580	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
UMN179_RS10585	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
UMN179_RS10590	COG3028	Belongs to the UPF0307 family
UMN179_RS10595	COG0312	modulator of DNA gyrase
UMN179_RS10600	COG0385	Bile acid
UMN179_RS10605	COG0825	malonyl-CoA metabolic process
UMN179_RS10620	COG0584	glycerophosphoryl diester phosphodiesterase
UMN179_RS10625	COG3842	ATPase activity
UMN179_RS10635	COG1176	ABC-type spermidine putrescine transport system, permease component I
UMN179_RS10660	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
UMN179_RS10665	COG1178	ABC-type Fe3 transport system permease component
UMN179_RS10670	COG4143	(ABC) transporter
UMN179_RS10690	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
UMN179_RS10690	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
UMN179_RS10695	COG0489	protein tyrosine kinase activity
UMN179_RS10725	COG2026	Addiction module toxin, RelE StbE family
UMN179_RS10740	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
UMN179_RS10755	COG1216	Glycosyl transferase, family 2
UMN179_RS10755	COG1442	glycosyl transferase family 8
UMN179_RS10765	COG2244	polysaccharide biosynthetic process
UMN179_RS10780	COG0562	UDP-galactopyranose mutase
UMN179_RS10785	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
UMN179_RS10795	COG1088	dTDP-glucose 4,6-dehydratase activity
UMN179_RS10810	COG0675	Transposase, IS605 OrfB family
UMN179_RS10815	COG2027	D-alanyl-D-alanine carboxypeptidase
UMN179_RS10820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
UMN179_RS10825	COG0318	PFAM AMP-dependent synthetase and ligase
UMN179_RS10830	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
UMN179_RS10835	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
UMN179_RS10840	COG3691	Protein conserved in bacteria
UMN179_RS10855	COG2830	Protein of unknown function (DUF452)
UMN179_RS10860	COG0500	methyltransferase
UMN179_RS10870	COG0779	Required for maturation of 30S ribosomal subunits
UMN179_RS10875	COG0195	Participates in both transcription termination and antitermination
UMN179_RS10885	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
UMN179_RS10945	COG0560	Phosphoserine phosphatase
UMN179_RS10955	COG0795	lipopolysaccharide-transporting ATPase activity
UMN179_RS10960	COG0795	lipopolysaccharide-transporting ATPase activity
UMN179_RS10965	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
UMN179_RS10970	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
UMN179_RS10970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
UMN179_RS10980	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
UMN179_RS10985	COG0508	dehydrogenase complex catalyzes the overall conversion of
UMN179_RS10990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
UMN179_RS10995	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
UMN179_RS11000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
UMN179_RS11005	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
UMN179_RS11010	COG1643	Atp-dependent helicase
UMN179_RS11020	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
UMN179_RS11020	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
UMN179_RS11025	COG0456	acetyltransferase
UMN179_RS11030	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
UMN179_RS11050	COG2166	iron-sulfur cluster assembly
UMN179_RS11060	COG1525	nuclease
UMN179_RS11065	COG1380	Effector of murein hydrolase LrgA
UMN179_RS11070	COG1346	cytolysis
UMN179_RS11075	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
UMN179_RS11075	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
UMN179_RS11080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
UMN179_RS11085	COG0527	aspartate kinase activity
UMN179_RS11090	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
UMN179_RS11095	COG3047	cAMP biosynthetic process
UMN179_RS11100	COG3189	MarR family transcriptional regulator
UMN179_RS11105	COG2268	Band 7 protein
UMN179_RS11110	COG2197	response regulator
UMN179_RS11120	COG0181	hydroxymethylbilane synthase activity
UMN179_RS11130	COG2959	enzyme of heme biosynthesis
UMN179_RS11135	COG3071	HemY protein
UMN179_RS11150	COG0814	amino acid
UMN179_RS11175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
UMN179_RS11180	COG4591	ABC-type transport system involved in lipoprotein release permease component
UMN179_RS11185	COG1136	(ABC) transporter
UMN179_RS11190	COG4591	ABC-type transport system involved in lipoprotein release permease component
UMN179_RS11195	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
UMN179_RS11200	COG1214	PFAM Peptidase M22, glycoprotease
UMN179_RS11205	COG1199	ATP-dependent helicase activity
UMN179_RS11210	COG0676	glucose-6-phosphate 1-epimerase activity
UMN179_RS11215	COG3099	Belongs to the UPF0263 family
UMN179_RS11245	COG3210	domain, Protein
UMN179_RS11275	COG3210	domain, Protein
UMN179_RS11280	COG2831	hemolysin activation secretion protein
UMN179_RS11285	COG1448	Aminotransferase
UMN179_RS11290	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
UMN179_RS11295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
UMN179_RS11300	COG0308	aminopeptidase N
UMN179_RS11315	COG0613	PHP domain protein
UMN179_RS11320	COG0009	L-threonylcarbamoyladenylate synthase
UMN179_RS11325	COG1187	pseudouridine synthase activity
UMN179_RS11330	COG0583	DNA-binding transcription factor activity
UMN179_RS11345	COG2731	YhcH YjgK YiaL family protein
UMN179_RS11350	COG1737	Transcriptional regulator
UMN179_RS11370	COG4771	TonB-dependent receptor
UMN179_RS11375	COG3721	Heme iron utilization protein
UMN179_RS11380	COG0748	coenzyme F420 binding
UMN179_RS11400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
UMN179_RS11405	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
UMN179_RS11410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
UMN179_RS11420	COG0295	cytidine deaminase activity
UMN179_RS11425	COG0564	pseudouridine synthase activity
UMN179_RS11445	COG0791	NLP P60 protein
UMN179_RS11455	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
UMN179_RS11475	COG1337	RAMP superfamily
UMN179_RS11530	COG1518	maintenance of DNA repeat elements
UMN179_RS11535	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
UMN179_RS11545	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
UMN179_RS11555	COG0497	DNA recombination
UMN179_RS11560	COG0488	(ABC) transporter
UMN179_RS11565	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
UMN179_RS11580	COG0811	peptide transport
UMN179_RS11585	COG0848	biopolymer transport protein
UMN179_RS11600	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
UMN179_RS11605	COG2153	protein acetylation
UMN179_RS11615	COG2807	transmembrane transport
UMN179_RS11620	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
UMN179_RS11625	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
UMN179_RS11635	COG3106	COG3106 Predicted ATPase
UMN179_RS11650	COG3477	response to acidic pH
UMN179_RS11655	COG4166	transmembrane transport
UMN179_RS11660	COG4168	peptide transport system, permease
UMN179_RS11665	COG4171	peptide transport system, permease
UMN179_RS11670	COG4172	Belongs to the ABC transporter superfamily
UMN179_RS11675	COG4172	Belongs to the ABC transporter superfamily
UMN179_RS11680	COG0668	transmembrane transport
UMN179_RS11690	COG1067	ATP-dependent peptidase activity
UMN179_RS11695	COG3118	belongs to the thioredoxin family
UMN179_RS11700	COG0492	ferredoxin-NADP+ reductase activity
UMN179_RS11705	COG4988	ABC transporter
UMN179_RS11710	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
UMN179_RS11740	COG0004	ammonium transporteR
UMN179_RS11745	COG0347	Belongs to the P(II) protein family
UMN179_RS11750	COG0633	Ferredoxin
UMN179_RS11750	COG3217	Mosc domain protein beta barrel domain protein
UMN179_RS11755	COG2814	Major facilitator Superfamily
UMN179_RS11795	COG2801	Transposase and inactivated derivatives
UMN179_RS11855	COG3617	BRO family, N-terminal domain
UMN179_RS11865	COG3093	addiction module antidote protein HigA
UMN179_RS11870	COG3549	Plasmid maintenance system killer
UMN179_RS11975	COG0740	serine-type endopeptidase activity
UMN179_RS12065	COG3093	addiction module antidote protein HigA
UMN179_RS12095	COG0518	GMP synthase (glutamine-hydrolyzing) activity
UMN179_RS12095	COG0519	Catalyzes the synthesis of GMP from XMP
UMN179_RS12100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
UMN179_RS12110	COG2837	iron assimilation
UMN179_RS12120	COG0675	Transposase, IS605 OrfB family
UMN179_RS12125	COG0582	viral genome integration into host DNA
UMN179_RS12155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
UMN179_RS12160	COG1121	(ABC) transporter
UMN179_RS12165	COG0739	heme binding
UMN179_RS12170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
UMN179_RS12175	COG0659	secondary active sulfate transmembrane transporter activity
UMN179_RS12190	COG2963	transposase activity
UMN179_RS12200	COG0101	tRNA pseudouridine synthase activity
UMN179_RS12205	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
UMN179_RS12210	COG0586	Pfam SNARE associated Golgi protein
UMN179_RS12215	COG3210	domain, Protein
UMN179_RS12255	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
UMN179_RS12260	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
UMN179_RS12265	COG1119	ATPase activity
UMN179_RS12270	COG2932	Transcriptional regulator
UMN179_RS12280	COG4221	oxidoreductase activity
UMN179_RS12285	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
UMN179_RS12290	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
UMN179_RS12295	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
UMN179_RS12310	COG0589	response to stress
UMN179_RS12320	COG1528	Iron-storage protein
UMN179_RS12325	COG1528	Iron-storage protein
UMN179_RS12335	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
UMN179_RS12350	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
UMN179_RS12355	COG0314	molybdopterin synthase activity
UMN179_RS12365	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
UMN179_RS12370	COG0280	phosphate acetyltransferase
UMN179_RS12370	COG0857	belongs to the CobB CobQ family
UMN179_RS12375	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
UMN179_RS12380	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
UMN179_RS12395	COG4695	Portal protein
UMN179_RS12515	COG3392	D12 class N6 adenine-specific DNA methyltransferase
UMN179_RS12605	COG0582	viral genome integration into host DNA
UMN179_RS12675	COG0697	spore germination
UMN179_RS12700	COG5301	cellulose 1,4-beta-cellobiosidase activity