locus-tag	class	description
GYMC61_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GYMC61_RS00010	COG0592	DNA-directed DNA polymerase activity
GYMC61_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GYMC61_RS00025	COG0187	DNA topoisomerase II activity
GYMC61_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GYMC61_RS00035	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GYMC61_RS00075	COG0516	GMP reductase activity
GYMC61_RS00075	COG0517	IMP dehydrogenase activity
GYMC61_RS00085	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GYMC61_RS00090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GYMC61_RS00095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GYMC61_RS00105	COG3858	chitin binding
GYMC61_RS00105	COG1388	LysM domain
GYMC61_RS00110	COG0590	tRNA wobble adenosine to inosine editing
GYMC61_RS00115	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GYMC61_RS00120	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GYMC61_RS00125	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GYMC61_RS00180	COG1982	Orn Lys Arg decarboxylase major
GYMC61_RS00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GYMC61_RS00190	COG0470	DNA polymerase III
GYMC61_RS00195	COG1774	PSP1 C-terminal conserved region
GYMC61_RS00200	COG4467	Involved in initiation control of chromosome replication
GYMC61_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GYMC61_RS00210	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GYMC61_RS00215	COG2002	toxin-antitoxin pair type II binding
GYMC61_RS00225	COG0084	hydrolase, TatD family'
GYMC61_RS00230	COG3584	3D domain protein
GYMC61_RS00230	COG3583	domain protein
GYMC61_RS00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GYMC61_RS00250	COG4466	Protein conserved in bacteria
GYMC61_RS00260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GYMC61_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GYMC61_RS00270	COG0251	oxidation-reduction process
GYMC61_RS00275	COG2088	sporulation resulting in formation of a cellular spore
GYMC61_RS00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GYMC61_RS00290	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GYMC61_RS00295	COG0193	aminoacyl-tRNA hydrolase activity
GYMC61_RS00305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GYMC61_RS00310	COG2002	toxin-antitoxin pair type II binding
GYMC61_RS00315	COG2244	polysaccharide biosynthetic process
GYMC61_RS00320	COG3956	TIGRFAM MazG family protein
GYMC61_RS00325	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GYMC61_RS00345	COG1098	S1 RNA binding domain
GYMC61_RS00360	COG2208	phosphoserine phosphatase activity
GYMC61_RS00365	COG2304	oxidoreductase activity
GYMC61_RS00370	COG0515	serine threonine protein kinase
GYMC61_RS00375	COG0037	tRNA processing
GYMC61_RS00380	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GYMC61_RS00385	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GYMC61_RS00390	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GYMC61_RS00395	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GYMC61_RS00400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GYMC61_RS00405	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GYMC61_RS00410	COG0512	Glutamine amidotransferase of anthranilate synthase
GYMC61_RS00415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GYMC61_RS00420	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GYMC61_RS00425	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GYMC61_RS00430	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GYMC61_RS00435	COG1396	sequence-specific DNA binding
GYMC61_RS00445	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GYMC61_RS00525	COG3880	PFAM UvrB UvrC protein
GYMC61_RS00530	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GYMC61_RS00535	COG0542	response to heat
GYMC61_RS00540	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GYMC61_RS00545	COG4956	integral membrane protein (PIN domain superfamily)
GYMC61_RS00550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GYMC61_RS00555	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GYMC61_RS00560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GYMC61_RS00565	COG1045	serine acetyltransferase
GYMC61_RS00570	COG0215	cysteine-tRNA ligase activity
GYMC61_RS00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GYMC61_RS00585	COG3688	RNA-binding protein containing a PIN domain
GYMC61_RS00595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GYMC61_RS00600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GYMC61_RS00605	COG0250	Participates in transcription elongation, termination and antitermination
GYMC61_RS00610	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GYMC61_RS00620	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GYMC61_RS00625	COG0222	ribosome binding
GYMC61_RS00630	COG2813	Specifically methylates the guanine in position
GYMC61_RS00640	COG0085	RNA polymerase activity
GYMC61_RS00645	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GYMC61_RS00650	COG1358	cellular component organization or biogenesis
GYMC61_RS00655	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GYMC61_RS00660	COG0049	tRNA binding
GYMC61_RS00670	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GYMC61_RS00675	COG0051	transcription antitermination factor activity, RNA binding
GYMC61_RS00680	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GYMC61_RS00685	COG0088	Forms part of the polypeptide exit tunnel
GYMC61_RS00690	COG0089	rRNA binding
GYMC61_RS00695	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GYMC61_RS00700	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GYMC61_RS00705	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GYMC61_RS00710	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GYMC61_RS00715	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GYMC61_RS00725	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GYMC61_RS00740	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GYMC61_RS00745	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GYMC61_RS00750	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GYMC61_RS00760	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GYMC61_RS00765	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GYMC61_RS00770	COG1841	ribosomal large subunit assembly
GYMC61_RS00780	COG0201	protein transport
GYMC61_RS00785	COG0563	adenylate kinase activity
GYMC61_RS00790	COG0024	Methionine aminopeptidase
GYMC61_RS00795	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GYMC61_RS00800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GYMC61_RS00805	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GYMC61_RS00810	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GYMC61_RS00815	COG0202	RNA polymerase activity
GYMC61_RS00820	COG0203	ribosomal protein L17
GYMC61_RS00825	COG1122	ATPase activity
GYMC61_RS00830	COG1122	ATPase activity
GYMC61_RS00835	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GYMC61_RS00840	COG0101	tRNA pseudouridine synthase activity
GYMC61_RS00845	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GYMC61_RS00850	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GYMC61_RS00860	COG0860	N-Acetylmuramoyl-L-alanine amidase
GYMC61_RS00865	COG0489	protein tyrosine kinase activity
GYMC61_RS00875	COG2194	sulfuric ester hydrolase activity
GYMC61_RS00880	COG0726	polysaccharide deacetylase
GYMC61_RS00950	COG1595	DNA-templated transcription, initiation
GYMC61_RS00955	COG5662	AntiSigma factor
GYMC61_RS00960	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GYMC61_RS00965	COG4856	YbbR-like protein
GYMC61_RS00970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GYMC61_RS00975	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GYMC61_RS00985	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GYMC61_RS00995	COG2010	Cytochrome c
GYMC61_RS01000	COG2384	SAM-dependent methyltransferase
GYMC61_RS01005	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GYMC61_RS01010	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GYMC61_RS01025	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GYMC61_RS01035	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GYMC61_RS01040	COG1121	(ABC) transporter
GYMC61_RS01045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GYMC61_RS01050	COG0735	belongs to the Fur family
GYMC61_RS01055	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
GYMC61_RS01060	COG4709	membrane
GYMC61_RS01065	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GYMC61_RS01070	COG1388	LysM domain
GYMC61_RS01080	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GYMC61_RS01085	COG0573	inorganic phosphate transmembrane transporter activity
GYMC61_RS01090	COG0581	inorganic phosphate transmembrane transporter activity
GYMC61_RS01095	COG5521	maltodextrose utilization protein MalA
GYMC61_RS01115	COG0477	Major facilitator Superfamily
GYMC61_RS01120	COG0768	penicillin binding
GYMC61_RS01125	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GYMC61_RS01145	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GYMC61_RS01160	COG0457	Tetratricopeptide repeat
GYMC61_RS01160	COG0705	Rhomboid family
GYMC61_RS01170	COG0697	spore germination
GYMC61_RS01175	COG4483	Protein conserved in bacteria
GYMC61_RS01180	COG1940	carbohydrate kinase activity
GYMC61_RS01195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GYMC61_RS01220	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GYMC61_RS01225	COG1459	type II secretion system
GYMC61_RS01230	COG4537	Required for transformation and DNA binding
GYMC61_RS01265	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GYMC61_RS01270	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GYMC61_RS01275	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GYMC61_RS01290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GYMC61_RS01295	COG0095	Lipoate-protein ligase
GYMC61_RS01310	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GYMC61_RS01315	COG1388	LysM domain
GYMC61_RS01315	COG3858	chitin binding
GYMC61_RS01335	COG1321	iron dependent repressor
GYMC61_RS01340	COG1752	Esterase of the alpha-beta hydrolase superfamily
GYMC61_RS01350	COG3872	metal-dependent enzyme
GYMC61_RS01360	COG0006	proline dipeptidase activity
GYMC61_RS01365	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GYMC61_RS01375	COG3854	ATPases associated with a variety of cellular activities
GYMC61_RS01415	COG0511	ligase activity, forming carbon-carbon bonds
GYMC61_RS01420	COG0439	Biotin carboxylase
GYMC61_RS01425	COG1302	Protein conserved in bacteria
GYMC61_RS01430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GYMC61_RS01435	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GYMC61_RS01440	COG1570	exodeoxyribonuclease VII activity
GYMC61_RS01445	COG1722	exodeoxyribonuclease VII activity
GYMC61_RS01455	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GYMC61_RS01460	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GYMC61_RS01465	COG1438	arginine binding
GYMC61_RS01470	COG0497	DNA recombination
GYMC61_RS01475	COG0750	zinc metalloprotease
GYMC61_RS01485	COG0584	glycerophosphoryl diester phosphodiesterase
GYMC61_RS01495	COG3829	transcription factor binding
GYMC61_RS01495	COG3290	protein histidine kinase activity
GYMC61_RS01500	COG0280	phosphate acetyltransferase
GYMC61_RS01510	COG3426	butyrate kinase activity
GYMC61_RS01515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GYMC61_RS01520	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GYMC61_RS01525	COG0022	dehydrogenase e1 component
GYMC61_RS01530	COG0508	dehydrogenase complex catalyzes the overall conversion of
GYMC61_RS01550	COG3547	Transposase (IS116 IS110 IS902 family)
GYMC61_RS01565	COG0745	RESPONSE REGULATOR receiver
GYMC61_RS01570	COG5002	protein histidine kinase activity
GYMC61_RS01590	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GYMC61_RS01590	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GYMC61_RS01595	COG1703	isobutyryl-CoA mutase activity
GYMC61_RS01625	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GYMC61_RS01630	COG0732	type I restriction modification DNA specificity domain
GYMC61_RS01635	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GYMC61_RS01670	COG1131	(ABC) transporter
GYMC61_RS01700	COG4129	membrane
GYMC61_RS01705	COG1376	ErfK ybiS ycfS ynhG family protein
GYMC61_RS01710	COG0346	lactoylglutathione lyase activity
GYMC61_RS01715	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GYMC61_RS01775	COG2195	Cleaves the N-terminal amino acid of tripeptides
GYMC61_RS01780	COG0784	Response regulator, receiver
GYMC61_RS01780	COG0835	chemotaxis
GYMC61_RS01790	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GYMC61_RS01860	COG0577	efflux transmembrane transporter activity
GYMC61_RS01865	COG1136	(ABC) transporter
GYMC61_RS01870	COG0642	Histidine kinase
GYMC61_RS01875	COG0745	RESPONSE REGULATOR receiver
GYMC61_RS01885	COG2723	6-phospho-beta-galactosidase activity
GYMC61_RS01895	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GYMC61_RS01900	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GYMC61_RS01905	COG1234	tRNA 3'-trailer cleavage
GYMC61_RS01910	COG1902	pentaerythritol trinitrate reductase activity
GYMC61_RS01915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GYMC61_RS01920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GYMC61_RS01925	COG0300	oxidoreductase activity
GYMC61_RS01940	COG4918	Iron-sulphur cluster biosynthesis
GYMC61_RS01955	COG2807	transmembrane transport
GYMC61_RS01960	COG0667	Aldo Keto reductase
GYMC61_RS01965	COG0494	nUDIX hydrolase
GYMC61_RS01970	COG1379	DNA repair
GYMC61_RS01975	COG1300	Membrane
GYMC61_RS01980	COG0735	belongs to the Fur family
GYMC61_RS01990	COG4974	Belongs to the 'phage' integrase family
GYMC61_RS01995	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GYMC61_RS02010	COG1686	Belongs to the peptidase S11 family
GYMC61_RS02020	COG2172	sigma factor antagonist activity
GYMC61_RS02025	COG1191	sigma factor activity
GYMC61_RS02045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GYMC61_RS02060	COG0697	spore germination
GYMC61_RS02065	COG0019	diaminopimelate decarboxylase activity
GYMC61_RS02070	COG4086	secreted protein
GYMC61_RS02075	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GYMC61_RS02080	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GYMC61_RS02080	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GYMC61_RS02085	COG0307	riboflavin synthase, alpha
GYMC61_RS02090	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GYMC61_RS02090	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GYMC61_RS02095	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GYMC61_RS02105	COG1547	Domain of unknown function (DUF309)
GYMC61_RS02110	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GYMC61_RS02115	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GYMC61_RS02125	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GYMC61_RS02130	COG1686	Belongs to the peptidase S11 family
GYMC61_RS02135	COG2715	membrane protein required for spore maturation
GYMC61_RS02140	COG0700	Nucleoside recognition
GYMC61_RS02145	COG1187	pseudouridine synthase activity
GYMC61_RS02150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GYMC61_RS02155	COG1333	cytochrome c biogenesis protein
GYMC61_RS02160	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GYMC61_RS02165	COG0745	RESPONSE REGULATOR receiver
GYMC61_RS02170	COG5002	protein histidine kinase activity
GYMC61_RS02175	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GYMC61_RS02180	COG0363	glucosamine-6-phosphate deaminase activity
GYMC61_RS02185	COG2188	Transcriptional regulator
GYMC61_RS02190	COG1263	PTS System
GYMC61_RS02190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GYMC61_RS02200	COG3275	phosphorelay sensor kinase activity
GYMC61_RS02205	COG3279	Response regulator of the LytR AlgR family
GYMC61_RS02220	COG0531	amino acid
GYMC61_RS02230	COG2816	NAD+ diphosphatase activity
GYMC61_RS02235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GYMC61_RS02240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GYMC61_RS02245	COG1120	ATPase activity
GYMC61_RS02250	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GYMC61_RS02255	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GYMC61_RS02265	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GYMC61_RS02280	COG2096	Adenosyltransferase
GYMC61_RS02295	COG1595	DNA-templated transcription, initiation
GYMC61_RS02305	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GYMC61_RS02310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GYMC61_RS02325	COG4955	Helix-turn-helix domain
GYMC61_RS02330	COG0514	ATP-dependent DNA helicase (RecQ)
GYMC61_RS02350	COG3546	catalase activity
GYMC61_RS02370	COG4862	establishment of competence for transformation
GYMC61_RS02375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GYMC61_RS02380	COG0492	ferredoxin-NADP+ reductase activity
GYMC61_RS02390	COG2339	peptidase activity
GYMC61_RS02395	COG3409	Peptidoglycan-binding domain 1 protein
GYMC61_RS02395	COG3773	Cell wall hydrolase
GYMC61_RS02400	COG2959	enzyme of heme biosynthesis
GYMC61_RS02415	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GYMC61_RS02420	COG0204	Acyl-transferase
GYMC61_RS02425	COG0539	negative regulation of cytoplasmic translation
GYMC61_RS02445	COG1160	GTP binding
GYMC61_RS02450	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GYMC61_RS02465	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GYMC61_RS02475	COG0302	gtp cyclohydrolase
GYMC61_RS02490	COG2226	methyltransferase
GYMC61_RS02500	COG0105	UTP biosynthetic process
GYMC61_RS02505	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GYMC61_RS02510	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GYMC61_RS02515	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GYMC61_RS02520	COG4401	Chorismate mutase type I
GYMC61_RS02530	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GYMC61_RS02535	COG0134	indole-3-glycerol-phosphate synthase activity
GYMC61_RS02540	COG0135	phosphoribosylanthranilate isomerase activity
GYMC61_RS02550	COG0159	tryptophan synthase activity
GYMC61_RS02555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GYMC61_RS02560	COG0287	Prephenate dehydrogenase
GYMC61_RS02565	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GYMC61_RS02570	COG0457	Tetratricopeptide repeat
GYMC61_RS02575	COG5582	Belongs to the UPF0302 family
GYMC61_RS02600	COG4347	Protein of unknown function (DUF1405)
GYMC61_RS02610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GYMC61_RS02615	COG1694	Mazg nucleotide pyrophosphohydrolase
GYMC61_RS02620	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GYMC61_RS02625	COG1803	Methylglyoxal synthase
GYMC61_RS02630	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GYMC61_RS02635	COG0438	transferase activity, transferring glycosyl groups
GYMC61_RS02640	COG0617	tRNA 3'-terminal CCA addition
GYMC61_RS02655	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GYMC61_RS02660	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GYMC61_RS02665	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GYMC61_RS02670	COG1199	ATP-dependent helicase activity
GYMC61_RS02670	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GYMC61_RS02700	COG0017	Asparaginyl-tRNA synthetase
GYMC61_RS02705	COG3935	DnaD domain protein
GYMC61_RS02710	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GYMC61_RS02715	COG4499	WXG100 protein secretion system (Wss), protein YukC
GYMC61_RS02715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GYMC61_RS02720	COG3331	DNA recombination
GYMC61_RS02765	COG0745	RESPONSE REGULATOR receiver
GYMC61_RS02770	COG5002	protein histidine kinase activity
GYMC61_RS02775	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GYMC61_RS02780	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GYMC61_RS02790	COG2217	Heavy metal translocating P-type atpase
GYMC61_RS02815	COG3250	beta-galactosidase activity
GYMC61_RS02820	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GYMC61_RS02825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GYMC61_RS02830	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
GYMC61_RS02835	COG1609	Transcriptional regulator
GYMC61_RS02840	COG0071	Belongs to the small heat shock protein (HSP20) family
GYMC61_RS02950	COG3547	Transposase (IS116 IS110 IS902 family)
GYMC61_RS02980	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GYMC61_RS02985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GYMC61_RS02990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GYMC61_RS03010	COG1280	lysine exporter protein (LysE YggA)
GYMC61_RS03025	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GYMC61_RS03035	COG0297	glycogen (starch) synthase activity
GYMC61_RS03040	COG0058	SHG alpha-glucan phosphorylase activity
GYMC61_RS03055	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GYMC61_RS03060	COG1575	Belongs to the MenA family. Type 1 subfamily
GYMC61_RS03065	COG1169	isochorismate synthase
GYMC61_RS03070	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GYMC61_RS03075	COG0596	Alpha beta hydrolase
GYMC61_RS03080	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GYMC61_RS03085	COG0318	PFAM AMP-dependent synthetase and ligase
GYMC61_RS03115	COG1294	oxidase, subunit
GYMC61_RS03120	COG1271	oxidase subunit
GYMC61_RS03130	COG0523	cobalamin synthesis protein
GYMC61_RS03135	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GYMC61_RS03140	COG1854	S-ribosylhomocysteine lyase activity
GYMC61_RS03150	COG0783	Belongs to the Dps family
GYMC61_RS03155	COG4824	toxin secretion phage lysis holin
GYMC61_RS03165	COG0494	nUDIX hydrolase
GYMC61_RS03170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GYMC61_RS03175	COG1116	anion transmembrane transporter activity
GYMC61_RS03180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GYMC61_RS03185	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GYMC61_RS03210	COG3646	Phage regulatory protein
GYMC61_RS03215	COG2002	toxin-antitoxin pair type II binding
GYMC61_RS03235	COG5377	YqaJ viral recombinase family
GYMC61_RS03240	COG3723	Recombinational DNA repair protein, rece pathway
GYMC61_RS03245	COG1522	sequence-specific DNA binding
GYMC61_RS03310	COG4626	Terminase
GYMC61_RS03310	COG1802	Transcriptional regulator
GYMC61_RS03325	COG0740	serine-type endopeptidase activity
GYMC61_RS03375	COG3953	SLT domain
GYMC61_RS03375	COG5280	Phage tail tape measure protein TP901
GYMC61_RS03410	COG4824	toxin secretion phage lysis holin
GYMC61_RS03445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GYMC61_RS03450	COG1506	peptidase
GYMC61_RS03475	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GYMC61_RS03480	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GYMC61_RS03485	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GYMC61_RS03495	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GYMC61_RS03510	COG2814	Major facilitator Superfamily
GYMC61_RS03515	COG0495	leucyl-tRNA aminoacylation
GYMC61_RS03520	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GYMC61_RS03540	COG2081	HI0933 family
GYMC61_RS03545	COG2244	polysaccharide biosynthetic process
GYMC61_RS03555	COG1187	pseudouridine synthase activity
GYMC61_RS03560	COG1349	DNA-binding transcription factor activity
GYMC61_RS03565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GYMC61_RS03585	COG1523	belongs to the glycosyl hydrolase 13 family
GYMC61_RS03590	COG0510	thiamine kinase activity
GYMC61_RS03600	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GYMC61_RS03605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GYMC61_RS03615	COG1363	Peptidase, m42
GYMC61_RS03620	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GYMC61_RS03630	COG4848	Belongs to the UPF0354 family
GYMC61_RS03635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GYMC61_RS03640	COG1674	ftsk spoiiie
GYMC61_RS03645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GYMC61_RS03660	COG3118	belongs to the thioredoxin family
GYMC61_RS03665	COG1605	Chorismate mutase
GYMC61_RS03665	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GYMC61_RS03685	COG2814	Major facilitator Superfamily
GYMC61_RS03725	COG0123	including yeast histone deacetylase and acetoin utilization protein
GYMC61_RS03730	COG0517	IMP dehydrogenase activity
GYMC61_RS03735	COG0454	-acetyltransferase
GYMC61_RS03740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GYMC61_RS03745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GYMC61_RS03755	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GYMC61_RS03760	COG2199	diguanylate cyclase activity
GYMC61_RS03760	COG2203	Gaf domain
GYMC61_RS03765	COG1956	GAF domain-containing protein
GYMC61_RS03770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GYMC61_RS03775	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GYMC61_RS03780	COG1104	cysteine desulfurase activity
GYMC61_RS03785	COG0301	tRNA thio-modification
GYMC61_RS03795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GYMC61_RS03800	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GYMC61_RS03805	COG0616	signal peptide processing
GYMC61_RS03810	COG1714	RDD family
GYMC61_RS03820	COG3874	Sporulation protein YtfJ
GYMC61_RS03825	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GYMC61_RS03830	COG0827	DNA restriction-modification system
GYMC61_RS03835	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GYMC61_RS03850	COG0318	PFAM AMP-dependent synthetase and ligase
GYMC61_RS03855	COG1960	acyl-CoA dehydrogenase activity
GYMC61_RS03860	COG1960	acyl-CoA dehydrogenase activity
GYMC61_RS03865	COG1024	Enoyl-CoA hydratase
GYMC61_RS03870	COG1028	Short-chain dehydrogenase reductase Sdr
GYMC61_RS03900	COG1012	belongs to the aldehyde dehydrogenase family
GYMC61_RS03905	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GYMC61_RS03930	COG0521	Mo-molybdopterin cofactor biosynthetic process
GYMC61_RS03945	COG1181	Belongs to the D-alanine--D-alanine ligase family
GYMC61_RS03955	COG0640	Transcriptional regulator
GYMC61_RS03960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GYMC61_RS03975	COG0137	argininosuccinate synthase activity
GYMC61_RS03980	COG0165	Argininosuccinate lyase
GYMC61_RS03985	COG0589	response to stress
GYMC61_RS03990	COG1028	Short-chain dehydrogenase reductase Sdr
GYMC61_RS04000	COG0006	proline dipeptidase activity
GYMC61_RS04005	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GYMC61_RS04010	COG4109	DRTGG domain
GYMC61_RS04020	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GYMC61_RS04035	COG0587	DNA-directed DNA polymerase activity
GYMC61_RS04045	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GYMC61_RS04050	COG0825	malonyl-CoA metabolic process
GYMC61_RS04055	COG0205	6-phosphofructokinase activity
GYMC61_RS04065	COG0628	permease
GYMC61_RS04070	COG2707	UPF0756 membrane protein
GYMC61_RS04075	COG0372	Belongs to the citrate synthase family
GYMC61_RS04080	COG0538	isocitrate dehydrogenase activity
GYMC61_RS04085	COG0039	L-malate dehydrogenase activity
GYMC61_RS04095	COG0745	RESPONSE REGULATOR receiver
GYMC61_RS04100	COG5002	protein histidine kinase activity
GYMC61_RS04110	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GYMC61_RS04115	COG0237	dephospho-CoA kinase activity
GYMC61_RS04120	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GYMC61_RS04125	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GYMC61_RS04135	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GYMC61_RS04140	COG3611	Membrane attachment protein
GYMC61_RS04145	COG1484	DNA-dependent DNA replication
GYMC61_RS04155	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GYMC61_RS04170	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GYMC61_RS04175	COG3326	Membrane
GYMC61_RS04185	COG1363	Peptidase, m42
GYMC61_RS04205	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GYMC61_RS04210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GYMC61_RS04220	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GYMC61_RS04225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GYMC61_RS04225	COG0072	phenylalanine-tRNA ligase activity
GYMC61_RS04230	COG1910	domain protein
GYMC61_RS04235	COG0725	ABC transporter, periplasmic molybdate-binding protein
GYMC61_RS04240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GYMC61_RS04245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GYMC61_RS04250	COG1785	Belongs to the alkaline phosphatase family
GYMC61_RS04255	COG1846	Transcriptional regulator
GYMC61_RS04260	COG2409	Drug exporters of the RND superfamily
GYMC61_RS04260	COG1033	growth of symbiont in host cell
GYMC61_RS04270	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GYMC61_RS04275	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GYMC61_RS04280	COG1286	toxin biosynthetic process
GYMC61_RS04285	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GYMC61_RS04285	COG1796	DNA polymerase
GYMC61_RS04290	COG1193	negative regulation of DNA recombination
GYMC61_RS04295	COG3766	membrane
GYMC61_RS04300	COG0318	PFAM AMP-dependent synthetase and ligase
GYMC61_RS04305	COG1309	transcriptional regulator
GYMC61_RS04310	COG1024	Enoyl-CoA hydratase
GYMC61_RS04315	COG2086	electron transfer activity
GYMC61_RS04320	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GYMC61_RS04325	COG3118	belongs to the thioredoxin family
GYMC61_RS04335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GYMC61_RS04370	COG0322	excinuclease ABC activity
GYMC61_RS04375	COG1719	4-vinyl reductase, 4VR
GYMC61_RS04380	COG2009	succinate dehydrogenase
GYMC61_RS04385	COG1053	succinate dehydrogenase
GYMC61_RS04390	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GYMC61_RS04395	COG2197	response regulator
GYMC61_RS04400	COG1846	Transcriptional regulator
GYMC61_RS04405	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GYMC61_RS04410	COG5401	PFAM Sporulation and spore germination
GYMC61_RS04415	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GYMC61_RS04420	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GYMC61_RS04425	COG0622	Phosphoesterase
GYMC61_RS04430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GYMC61_RS04440	COG0028	Belongs to the TPP enzyme family
GYMC61_RS04445	COG0440	acetolactate synthase activity
GYMC61_RS04455	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GYMC61_RS04460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GYMC61_RS04465	COG0473	3-isopropylmalate dehydrogenase activity
GYMC61_RS04470	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GYMC61_RS04475	COG0066	3-isopropylmalate dehydratase activity
GYMC61_RS04485	COG0544	peptidyl-prolyl cis-trans isomerase activity
GYMC61_RS04490	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GYMC61_RS04495	COG0470	DNA polymerase III
GYMC61_RS04495	COG1067	ATP-dependent peptidase activity
GYMC61_RS04500	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GYMC61_RS04505	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GYMC61_RS04515	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GYMC61_RS04520	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GYMC61_RS04525	COG0181	hydroxymethylbilane synthase activity
GYMC61_RS04535	COG0113	porphobilinogen synthase activity
GYMC61_RS04540	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GYMC61_RS04545	COG1388	LysM domain
GYMC61_RS04545	COG1388	LysM domain
GYMC61_RS04560	COG0525	valine-tRNA ligase activity
GYMC61_RS04565	COG0285	dihydrofolate synthase activity
GYMC61_RS04570	COG5492	domain, Protein
GYMC61_RS04605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GYMC61_RS04615	COG1459	type II secretion system
GYMC61_RS04625	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GYMC61_RS04655	COG0424	maF-like protein
GYMC61_RS04660	COG2003	Belongs to the UPF0758 family
GYMC61_RS04665	COG1077	Cell shape determining protein MreB Mrl
GYMC61_RS04670	COG1792	Involved in formation and maintenance of cell shape
GYMC61_RS04680	COG0850	regulation of cytokinetic process
GYMC61_RS04685	COG2894	cell division
GYMC61_RS04690	COG0739	heme binding
GYMC61_RS04695	COG1994	Peptidase M50
GYMC61_RS04700	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GYMC61_RS04705	COG2868	ribosomal protein
GYMC61_RS04710	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GYMC61_RS04715	COG3290	protein histidine kinase activity
GYMC61_RS04725	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GYMC61_RS04730	COG4492	Belongs to the UPF0735 family
GYMC61_RS04735	COG0077	Prephenate dehydratase
GYMC61_RS04740	COG1827	regulation of RNA biosynthetic process
GYMC61_RS04745	COG1104	cysteine desulfurase activity
GYMC61_RS04750	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GYMC61_RS04755	COG0157	Belongs to the NadC ModD family
GYMC61_RS04760	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GYMC61_RS04765	COG1388	LysM domain
GYMC61_RS04775	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GYMC61_RS04785	COG0217	transcriptional regulatory protein
GYMC61_RS04795	COG0632	four-way junction helicase activity
GYMC61_RS04800	COG2255	four-way junction helicase activity
GYMC61_RS04810	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GYMC61_RS04815	COG0343	queuine tRNA-ribosyltransferase activity
GYMC61_RS04820	COG1862	Preprotein translocase
GYMC61_RS04830	COG2244	polysaccharide biosynthetic process
GYMC61_RS04840	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GYMC61_RS04840	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GYMC61_RS04845	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GYMC61_RS04850	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GYMC61_RS04850	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GYMC61_RS04855	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GYMC61_RS04860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GYMC61_RS04875	COG0450	alkyl hydroperoxide reductase
GYMC61_RS04880	COG3634	alkyl hydroperoxide reductase activity
GYMC61_RS04885	COG0124	histidyl-tRNA synthetase
GYMC61_RS04890	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GYMC61_RS04900	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GYMC61_RS04910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GYMC61_RS04915	COG1309	transcriptional regulator
GYMC61_RS04920	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GYMC61_RS04925	COG2364	Membrane
GYMC61_RS04930	COG1959	2 iron, 2 sulfur cluster binding
GYMC61_RS04935	COG1104	cysteine desulfurase activity
GYMC61_RS04940	COG0482	sulfurtransferase activity
GYMC61_RS04950	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GYMC61_RS04965	COG0628	permease
GYMC61_RS04970	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GYMC61_RS04975	COG4472	Bacterial protein of unknown function (DUF965)
GYMC61_RS04980	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GYMC61_RS04985	COG3906	Belongs to the UPF0473 family
GYMC61_RS04990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GYMC61_RS04995	COG4122	O-methyltransferase activity
GYMC61_RS05000	COG0826	peptidase U32
GYMC61_RS05005	COG0826	peptidase U32
GYMC61_RS05010	COG0572	uridine kinase
GYMC61_RS05020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GYMC61_RS05025	COG0768	penicillin binding
GYMC61_RS05040	COG2226	methyltransferase
GYMC61_RS05045	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GYMC61_RS05050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GYMC61_RS05055	COG0626	cystathionine gamma-synthase activity
GYMC61_RS05080	COG0586	Pfam SNARE associated Golgi protein
GYMC61_RS05090	COG1360	Flagellar Motor Protein
GYMC61_RS05095	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GYMC61_RS05105	COG0688	phosphatidylethanolamine metabolic process
GYMC61_RS05115	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GYMC61_RS05120	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GYMC61_RS05125	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GYMC61_RS05130	COG1534	Rna-binding protein
GYMC61_RS05135	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GYMC61_RS05140	COG1713	HD superfamily hydrolase involved in NAD metabolism
GYMC61_RS05145	COG0799	negative regulation of ribosome biogenesis
GYMC61_RS05150	COG2226	methyltransferase
GYMC61_RS05155	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GYMC61_RS05160	COG1555	photosystem II stabilization
GYMC61_RS05160	COG1596	polysaccharide export
GYMC61_RS05165	COG2131	deaminase
GYMC61_RS05170	COG2333	competence protein COMEC
GYMC61_RS05170	COG0658	competence protein
GYMC61_RS05180	COG1466	dna polymerase III delta subunit
GYMC61_RS05185	COG0268	Binds directly to 16S ribosomal RNA
GYMC61_RS05190	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GYMC61_RS05195	COG0860	N-Acetylmuramoyl-L-alanine amidase
GYMC61_RS05205	COG0481	GTPase activity
GYMC61_RS05210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GYMC61_RS05215	COG1420	regulation of RNA biosynthetic process
GYMC61_RS05220	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GYMC61_RS05225	COG0443	Heat shock 70 kDa protein
GYMC61_RS05230	COG0484	heat shock protein binding
GYMC61_RS05235	COG2264	protein methyltransferase activity
GYMC61_RS05240	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GYMC61_RS05245	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GYMC61_RS05250	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GYMC61_RS05255	COG1283	sodium-dependent phosphate transmembrane transporter activity
GYMC61_RS05260	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GYMC61_RS05265	COG1610	YqeY-like protein
GYMC61_RS05280	COG1702	phosphate starvation-inducible protein PhoH
GYMC61_RS05285	COG1480	7TM receptor with intracellular HD hydrolase
GYMC61_RS05290	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GYMC61_RS05295	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GYMC61_RS05300	COG0295	cytidine deaminase activity
GYMC61_RS05305	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GYMC61_RS05310	COG1381	Involved in DNA repair and RecF pathway recombination
GYMC61_RS05315	COG0517	IMP dehydrogenase activity
GYMC61_RS05320	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GYMC61_RS05340	COG3655	Transcriptional regulator
GYMC61_RS05345	COG3739	integral membrane protein
GYMC61_RS05350	COG2318	DinB family
GYMC61_RS05355	COG0084	hydrolase, TatD family'
GYMC61_RS05360	COG3829	transcription factor binding
GYMC61_RS05365	COG0833	amino acid
GYMC61_RS05370	COG1012	belongs to the aldehyde dehydrogenase family
GYMC61_RS05375	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GYMC61_RS05380	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GYMC61_RS05385	COG0586	Pfam SNARE associated Golgi protein
GYMC61_RS05390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GYMC61_RS05395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GYMC61_RS05400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GYMC61_RS05405	COG1120	ATPase activity
GYMC61_RS05410	COG3829	transcription factor binding
GYMC61_RS05410	COG3290	protein histidine kinase activity
GYMC61_RS05415	COG1960	acyl-CoA dehydrogenase activity
GYMC61_RS05425	COG1012	belongs to the aldehyde dehydrogenase family
GYMC61_RS05430	COG1454	alcohol dehydrogenase
GYMC61_RS05440	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GYMC61_RS05445	COG2318	DinB family
GYMC61_RS05450	COG2197	response regulator
GYMC61_RS05460	COG1131	(ABC) transporter
GYMC61_RS05475	COG0860	N-Acetylmuramoyl-L-alanine amidase
GYMC61_RS05480	COG1404	Belongs to the peptidase S8 family
GYMC61_RS05485	COG1368	sulfuric ester hydrolase activity
GYMC61_RS05490	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GYMC61_RS05495	COG0531	amino acid
GYMC61_RS05500	COG1971	Probably functions as a manganese efflux pump
GYMC61_RS05510	COG5577	PFAM Coat F domain
GYMC61_RS05515	COG1940	carbohydrate kinase activity
GYMC61_RS05520	COG1968	undecaprenyl-diphosphatase activity
GYMC61_RS05550	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GYMC61_RS05560	COG0586	Pfam SNARE associated Golgi protein
GYMC61_RS05565	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GYMC61_RS05570	COG1181	Belongs to the D-alanine--D-alanine ligase family
GYMC61_RS05575	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GYMC61_RS05585	COG0513	Belongs to the DEAD box helicase family
GYMC61_RS05590	COG0705	Rhomboid family
GYMC61_RS05595	COG0736	holo-[acyl-carrier-protein] synthase activity
GYMC61_RS05600	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GYMC61_RS05605	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GYMC61_RS05610	COG0864	Transcriptional regulator
GYMC61_RS05615	COG2337	Toxic component of a toxin-antitoxin (TA) module
GYMC61_RS05620	COG2183	response to ionizing radiation
GYMC61_RS05625	COG3091	SprT-like family
GYMC61_RS05715	COG0802	atpase or kinase
GYMC61_RS05720	COG1214	PFAM Peptidase M22, glycoprotease
GYMC61_RS05725	COG0456	acetyltransferase
GYMC61_RS05730	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GYMC61_RS05735	COG0488	(ABC) transporter
GYMC61_RS05740	COG0315	cyclic pyranopterin monophosphate synthase activity
GYMC61_RS05745	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GYMC61_RS05750	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GYMC61_RS05755	COG0805	protein transport
GYMC61_RS05770	COG1266	CAAX protease self-immunity
GYMC61_RS05775	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GYMC61_RS05780	COG0459	protein refolding
GYMC61_RS05805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GYMC61_RS05810	COG2252	PERMEase
GYMC61_RS05815	COG0519	Catalyzes the synthesis of GMP from XMP
GYMC61_RS05815	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GYMC61_RS05820	COG1305	Transglutaminase-like
GYMC61_RS05825	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GYMC61_RS05830	COG0714	Associated with various cellular activities
GYMC61_RS05835	COG0114	fumarate hydratase activity
GYMC61_RS05860	COG3335	DDE superfamily endonuclease
GYMC61_RS05875	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GYMC61_RS05880	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GYMC61_RS05885	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GYMC61_RS05890	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GYMC61_RS05895	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GYMC61_RS05900	COG0047	phosphoribosylformylglycinamidine synthase activity
GYMC61_RS05905	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GYMC61_RS05910	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GYMC61_RS05915	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GYMC61_RS05920	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GYMC61_RS05925	COG0138	bifunctional purine biosynthesis protein purh
GYMC61_RS05930	COG0151	Belongs to the GarS family
GYMC61_RS05940	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GYMC61_RS05945	COG1470	cell adhesion involved in biofilm formation
GYMC61_RS05950	COG4496	protein, YerC YecD
GYMC61_RS05955	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GYMC61_RS05965	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GYMC61_RS05970	COG4851	CamS sex pheromone cAM373 precursor
GYMC61_RS05975	COG1611	Belongs to the LOG family
GYMC61_RS05980	COG1231	oxidoreductase activity
GYMC61_RS06000	COG0154	amidase activity
GYMC61_RS06005	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GYMC61_RS06045	COG1131	(ABC) transporter
GYMC61_RS06055	COG5002	protein histidine kinase activity
GYMC61_RS06075	COG1131	(ABC) transporter
GYMC61_RS06085	COG1174	glycine betaine transport
GYMC61_RS06090	COG1125	glycine betaine transport
GYMC61_RS06090	COG0517	IMP dehydrogenase activity
GYMC61_RS06095	COG1732	Glycine betaine
GYMC61_RS06155	COG1518	maintenance of DNA repeat elements
GYMC61_RS06160	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GYMC61_RS06220	COG3344	reverse transcriptase
GYMC61_RS06225	COG2814	Major facilitator Superfamily
GYMC61_RS06255	COG1511	domain protein
GYMC61_RS06260	COG1309	transcriptional regulator
GYMC61_RS06265	COG5002	protein histidine kinase activity
GYMC61_RS06280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GYMC61_RS06315	COG2268	Band 7 protein
GYMC61_RS06320	COG1597	lipid kinase activity
GYMC61_RS06325	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GYMC61_RS06355	COG0640	Transcriptional regulator
GYMC61_RS06360	COG3832	glyoxalase III activity
GYMC61_RS06365	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GYMC61_RS06370	COG4326	sporulation control protein
GYMC61_RS06375	COG0494	nUDIX hydrolase
GYMC61_RS06385	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GYMC61_RS06390	COG0297	glycogen (starch) synthase activity
GYMC61_RS06405	COG2197	response regulator
GYMC61_RS06420	COG2208	phosphoserine phosphatase activity
GYMC61_RS06425	COG1714	RDD family
GYMC61_RS06435	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GYMC61_RS06445	COG0436	Aminotransferase
GYMC61_RS06450	COG0028	Belongs to the TPP enzyme family
GYMC61_RS06455	COG1012	belongs to the aldehyde dehydrogenase family
GYMC61_RS06465	COG2814	Major facilitator Superfamily
GYMC61_RS06470	COG0789	Transcriptional regulator
GYMC61_RS06485	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GYMC61_RS06495	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GYMC61_RS06515	COG2986	histidine ammonia-lyase
GYMC61_RS06520	COG0861	Integral membrane protein TerC family
GYMC61_RS06550	COG1556	Lactate utilization protein
GYMC61_RS06555	COG1139	Iron-sulfur cluster binding protein
GYMC61_RS06560	COG0247	lactate metabolic process
GYMC61_RS06565	COG2186	Transcriptional regulator
GYMC61_RS06570	COG1620	l-lactate permease
GYMC61_RS06575	COG1077	Cell shape determining protein MreB Mrl
GYMC61_RS06580	COG0791	NLP P60 protein
GYMC61_RS06580	COG1388	LysM domain
GYMC61_RS06585	COG5001	Diguanylate cyclase
GYMC61_RS06585	COG3300	MHYT domain
GYMC61_RS06600	COG1648	precorrin-2 dehydrogenase activity
GYMC61_RS06600	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GYMC61_RS06605	COG0384	phenazine biosynthesis protein PhzF
GYMC61_RS06615	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GYMC61_RS06620	COG0010	Belongs to the arginase family
GYMC61_RS06625	COG1254	Belongs to the acylphosphatase family
GYMC61_RS06640	COG0529	Catalyzes the synthesis of activated sulfate
GYMC61_RS06645	COG2046	Belongs to the sulfate adenylyltransferase family
GYMC61_RS06655	COG0175	sulfate reduction
GYMC61_RS06660	COG4840	Belongs to the UPF0435 family
GYMC61_RS06665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GYMC61_RS06670	COG1295	ribonuclease BN
GYMC61_RS06680	COG0477	Major facilitator Superfamily
GYMC61_RS06685	COG0387	Pfam Sodium calcium exchanger
GYMC61_RS06695	COG0535	radical SAM domain protein
GYMC61_RS06710	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GYMC61_RS06715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GYMC61_RS06740	COG4758	membrane
GYMC61_RS06745	COG4585	Histidine kinase
GYMC61_RS06750	COG2197	response regulator
GYMC61_RS06760	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GYMC61_RS06770	COG0789	Transcriptional regulator
GYMC61_RS06795	COG5609	conserved protein (DUF2294)
GYMC61_RS06800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GYMC61_RS06805	COG3002	Belongs to the UPF0753 family
GYMC61_RS06815	COG1960	acyl-CoA dehydrogenase activity
GYMC61_RS06820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GYMC61_RS06825	COG1442	glycosyl transferase family 8
GYMC61_RS06840	COG1090	epimerase
GYMC61_RS06845	COG2137	regulation of response to DNA damage stimulus
GYMC61_RS06860	COG1988	membrane-bound metal-dependent
GYMC61_RS06865	COG2427	Protein of unknown function (DUF1641)
GYMC61_RS06870	COG3383	formate dehydrogenase (NAD+) activity
GYMC61_RS06875	COG5609	conserved protein (DUF2294)
GYMC61_RS06880	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GYMC61_RS06885	COG2223	nitrite transmembrane transporter activity
GYMC61_RS06900	COG1028	Short-chain dehydrogenase reductase Sdr
GYMC61_RS06915	COG3557	Belongs to the UPF0374 family
GYMC61_RS06925	COG0747	negative chemotaxis
GYMC61_RS06930	COG0601	transmembrane transport
GYMC61_RS06935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GYMC61_RS06940	COG4129	membrane
GYMC61_RS06945	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GYMC61_RS06950	COG4555	ABC transporter
GYMC61_RS06965	COG0039	L-malate dehydrogenase activity
GYMC61_RS06975	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GYMC61_RS06980	COG0735	belongs to the Fur family
GYMC61_RS07125	COG3382	B3 4 domain protein
GYMC61_RS07145	COG2766	serine protein kinase
GYMC61_RS07170	COG3290	protein histidine kinase activity
GYMC61_RS07175	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GYMC61_RS07180	COG1301	dicarboxylic acid transport
GYMC61_RS07185	COG0656	L-ascorbic acid biosynthetic process
GYMC61_RS07190	COG2738	Putative neutral zinc metallopeptidase
GYMC61_RS07195	COG1253	flavin adenine dinucleotide binding
GYMC61_RS07200	COG0564	pseudouridine synthase activity
GYMC61_RS07215	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GYMC61_RS07220	COG0517	IMP dehydrogenase activity
GYMC61_RS07225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GYMC61_RS07240	COG0586	Pfam SNARE associated Golgi protein
GYMC61_RS07245	COG2719	SpoVR family
GYMC61_RS07265	COG2719	SpoVR family
GYMC61_RS07270	COG1271	oxidase subunit
GYMC61_RS07295	COG0861	Integral membrane protein TerC family
GYMC61_RS07305	COG1966	Carbon starvation protein
GYMC61_RS07310	COG2879	small protein
GYMC61_RS07315	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GYMC61_RS07320	COG0366	Alpha amylase catalytic
GYMC61_RS07325	COG2318	DinB family
GYMC61_RS07330	COG2814	Major facilitator Superfamily
GYMC61_RS07340	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GYMC61_RS07345	COG4721	ABC-type cobalt transport system, permease component
GYMC61_RS07350	COG1122	ATPase activity
GYMC61_RS07355	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GYMC61_RS07360	COG0352	thiamine-phosphate diphosphorylase activity
GYMC61_RS07365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GYMC61_RS07375	COG2022	thiamine diphosphate biosynthetic process
GYMC61_RS07380	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GYMC61_RS07385	COG1253	flavin adenine dinucleotide binding
GYMC61_RS07390	COG3344	reverse transcriptase
GYMC61_RS07405	COG3842	ATPase activity
GYMC61_RS07410	COG2508	Transcriptional regulator
GYMC61_RS07430	COG0189	ligase activity
GYMC61_RS07435	COG0189	ligase activity
GYMC61_RS07445	COG4399	Belongs to the UPF0754 family
GYMC61_RS07450	COG3679	Belongs to the UPF0342 family
GYMC61_RS07455	COG0561	phosphatase activity
GYMC61_RS07475	COG1131	(ABC) transporter
GYMC61_RS07505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GYMC61_RS07530	COG4152	abc transporter atp-binding protein
GYMC61_RS07535	COG1668	transmembrane transport
GYMC61_RS07540	COG3481	metal-dependent phosphohydrolase, HD sub domain
GYMC61_RS07550	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GYMC61_RS07565	COG1846	Transcriptional regulator
GYMC61_RS07580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GYMC61_RS07585	COG0537	adenosine 5'-monophosphoramidase activity
GYMC61_RS07590	COG1131	(ABC) transporter
GYMC61_RS07595	COG4473	ABC transporter
GYMC61_RS07600	COG3069	C4-dicarboxylate transmembrane transporter activity
GYMC61_RS07605	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GYMC61_RS07610	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GYMC61_RS07615	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GYMC61_RS07620	COG1309	transcriptional regulator
GYMC61_RS07625	COG1511	domain protein
GYMC61_RS07625	COG1511	domain protein
GYMC61_RS07630	COG1234	tRNA 3'-trailer cleavage
GYMC61_RS07635	COG0318	PFAM AMP-dependent synthetase and ligase
GYMC61_RS07650	COG1116	anion transmembrane transporter activity
GYMC61_RS07660	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GYMC61_RS07675	COG2224	Isocitrate lyase
GYMC61_RS07690	COG0398	Pfam SNARE associated Golgi protein
GYMC61_RS07700	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GYMC61_RS07705	COG1074	ATP-dependent DNA helicase activity
GYMC61_RS07710	COG0420	3'-5' exonuclease activity
GYMC61_RS07715	COG0419	ATPase involved in DNA repair
GYMC61_RS07760	COG0318	PFAM AMP-dependent synthetase and ligase
GYMC61_RS07765	COG2311	Membrane
GYMC61_RS07775	COG0179	Fumarylacetoacetate (FAA) hydrolase
GYMC61_RS07795	COG0367	asparagine synthase
GYMC61_RS07800	COG0534	Mate efflux family protein
GYMC61_RS07810	COG2207	Transcriptional regulator
GYMC61_RS07820	COG2182	Extracellular solute-binding protein
GYMC61_RS07825	COG1175	transmembrane transport
GYMC61_RS07830	COG3833	ABC-type maltose transport systems, permease component
GYMC61_RS07835	COG0366	Alpha amylase catalytic
GYMC61_RS07850	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GYMC61_RS07855	COG0022	dehydrogenase e1 component
GYMC61_RS07865	COG1028	Short-chain dehydrogenase reductase Sdr
GYMC61_RS07880	COG1410	methionine synthase
GYMC61_RS07880	COG0646	methionine synthase
GYMC61_RS07885	COG0646	methionine synthase
GYMC61_RS07885	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GYMC61_RS07910	COG4133	protoheme IX ABC transporter activity
GYMC61_RS07915	COG3842	ATPase activity
GYMC61_RS07920	COG1176	ABC-type spermidine putrescine transport system, permease component I
GYMC61_RS07925	COG1177	transmembrane transport
GYMC61_RS07930	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GYMC61_RS07945	COG4555	ABC transporter
GYMC61_RS07950	COG0501	Belongs to the peptidase M48B family
GYMC61_RS07955	COG1666	GTP binding
GYMC61_RS07960	COG3177	Filamentation induced by cAMP protein fic
GYMC61_RS07965	COG1307	EDD domain protein, DegV family
GYMC61_RS07975	COG0561	phosphatase activity
GYMC61_RS07980	COG1073	alpha beta
GYMC61_RS08005	COG2151	metal-sulfur cluster biosynthetic enzyme
GYMC61_RS08025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GYMC61_RS08060	COG0746	molybdenum cofactor guanylyltransferase activity
GYMC61_RS08070	COG2197	response regulator
GYMC61_RS08090	COG1131	(ABC) transporter
GYMC61_RS08100	COG1136	(ABC) transporter
GYMC61_RS08110	COG0535	radical SAM domain protein
GYMC61_RS08140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GYMC61_RS08145	COG4149	molybdate abc transporter
GYMC61_RS08150	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GYMC61_RS08160	COG0840	transmembrane signaling receptor activity
GYMC61_RS08160	COG3290	protein histidine kinase activity
GYMC61_RS08165	COG0303	'Molybdopterin
GYMC61_RS08170	COG1763	Mo-molybdopterin cofactor biosynthetic process
GYMC61_RS08175	COG0314	molybdopterin synthase activity
GYMC61_RS08180	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GYMC61_RS08195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GYMC61_RS08200	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GYMC61_RS08205	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GYMC61_RS08210	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GYMC61_RS08250	COG2267	carboxylic ester hydrolase activity
GYMC61_RS08260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GYMC61_RS08265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GYMC61_RS08270	COG5504	Zn-dependent protease
GYMC61_RS08295	COG4166	transmembrane transport
GYMC61_RS08300	COG0601	transmembrane transport
GYMC61_RS08305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GYMC61_RS08310	COG0444	Belongs to the ABC transporter superfamily
GYMC61_RS08315	COG4608	Belongs to the ABC transporter superfamily
GYMC61_RS08325	COG1393	Belongs to the ArsC family
GYMC61_RS08330	COG0861	Integral membrane protein TerC family
GYMC61_RS08335	COG4862	establishment of competence for transformation
GYMC61_RS08340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GYMC61_RS08350	COG1164	Oligoendopeptidase f
GYMC61_RS08360	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GYMC61_RS08365	COG2346	COG2346, Truncated hemoglobins
GYMC61_RS08370	COG0741	lytic transglycosylase activity
GYMC61_RS08375	COG4116	CYTH
GYMC61_RS08385	COG2357	RelA SpoT domain protein
GYMC61_RS08395	COG0564	pseudouridine synthase activity
GYMC61_RS08400	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GYMC61_RS08405	COG0772	Belongs to the SEDS family
GYMC61_RS08425	COG0438	transferase activity, transferring glycosyl groups
GYMC61_RS08430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GYMC61_RS08435	COG0438	transferase activity, transferring glycosyl groups
GYMC61_RS08440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GYMC61_RS08445	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GYMC61_RS08510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GYMC61_RS08525	COG2323	membrane
GYMC61_RS08530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GYMC61_RS08545	COG2153	protein acetylation
GYMC61_RS08550	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GYMC61_RS08555	COG2382	esterase
GYMC61_RS08560	COG0626	cystathionine gamma-synthase activity
GYMC61_RS08565	COG0626	cystathionine gamma-synthase activity
GYMC61_RS08570	COG3437	response regulator, receiver
GYMC61_RS08570	COG2770	Histidine kinase
GYMC61_RS08590	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
GYMC61_RS08595	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GYMC61_RS08600	COG0732	type I restriction modification DNA specificity domain
GYMC61_RS08605	COG0840	transmembrane signaling receptor activity
GYMC61_RS08605	COG3290	protein histidine kinase activity
GYMC61_RS08625	COG0583	DNA-binding transcription factor activity
GYMC61_RS08670	COG1937	Protein conserved in bacteria
GYMC61_RS08675	COG2217	Heavy metal translocating P-type atpase
GYMC61_RS08690	COG2132	Multicopper oxidase
GYMC61_RS08695	COG4990	cell redox homeostasis
GYMC61_RS08700	COG0367	asparagine synthase
GYMC61_RS08705	COG5002	protein histidine kinase activity
GYMC61_RS08710	COG0745	RESPONSE REGULATOR receiver
GYMC61_RS08725	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GYMC61_RS08730	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GYMC61_RS08740	COG1418	mRNA catabolic process
GYMC61_RS08765	COG0477	Major facilitator Superfamily
GYMC61_RS08775	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GYMC61_RS08780	COG1597	lipid kinase activity
GYMC61_RS08785	COG2966	Psort location CytoplasmicMembrane, score
GYMC61_RS08795	COG1473	amidohydrolase
GYMC61_RS08805	COG4948	Mandelate Racemase Muconate Lactonizing
GYMC61_RS08825	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GYMC61_RS08830	COG3162	membrane
GYMC61_RS08835	COG0531	amino acid
GYMC61_RS08855	COG1609	Transcriptional regulator
GYMC61_RS08875	COG0395	ABC-type sugar transport system, permease component
GYMC61_RS08880	COG2814	Major facilitator Superfamily
GYMC61_RS08900	COG5002	protein histidine kinase activity
GYMC61_RS08905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GYMC61_RS08910	COG4214	carbohydrate transport
GYMC61_RS08915	COG1129	ABC transporter
GYMC61_RS08920	COG1879	ABC-type sugar transport system periplasmic component
GYMC61_RS08925	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GYMC61_RS08930	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GYMC61_RS08935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GYMC61_RS08940	COG0436	Aminotransferase
GYMC61_RS08945	COG1850	ribulose-bisphosphate carboxylase activity
GYMC61_RS08950	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GYMC61_RS08955	COG0235	Class ii aldolase
GYMC61_RS08960	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GYMC61_RS08970	COG1846	Transcriptional regulator
GYMC61_RS08975	COG4869	propanediol catabolic process
GYMC61_RS08985	COG1506	peptidase
GYMC61_RS08985	COG4946	Tricorn protease homolog
GYMC61_RS08985	COG0823	Involved in the tonB-independent uptake of proteins
GYMC61_RS08990	COG0531	amino acid
GYMC61_RS09005	COG1131	(ABC) transporter
GYMC61_RS09035	COG0542	response to heat
GYMC61_RS09045	COG3949	Membrane
GYMC61_RS09050	COG0840	transmembrane signaling receptor activity
GYMC61_RS09070	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GYMC61_RS09075	COG0720	synthase
GYMC61_RS09085	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GYMC61_RS09090	COG0702	epimerase
GYMC61_RS09095	COG4873	Protein conserved in bacteria
GYMC61_RS09100	COG3773	Cell wall hydrolase
GYMC61_RS09115	COG1028	Short-chain dehydrogenase reductase Sdr
GYMC61_RS09125	COG4191	Histidine kinase
GYMC61_RS09130	COG0475	glutathione-regulated potassium exporter activity
GYMC61_RS09135	COG3711	transcriptional antiterminator
GYMC61_RS09140	COG1263	PTS System
GYMC61_RS09140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GYMC61_RS09140	COG2190	(PTS) system
GYMC61_RS09165	COG0860	N-Acetylmuramoyl-L-alanine amidase
GYMC61_RS09165	COG3409	Peptidoglycan-binding domain 1 protein
GYMC61_RS09175	COG0456	acetyltransferase
GYMC61_RS09185	COG0840	transmembrane signaling receptor activity
GYMC61_RS09190	COG0567	Dehydrogenase, E1 component
GYMC61_RS09195	COG0508	dehydrogenase complex catalyzes the overall conversion of
GYMC61_RS09205	COG1028	Short-chain dehydrogenase reductase Sdr
GYMC61_RS09210	COG2084	Dehydrogenase
GYMC61_RS09220	COG1028	Short-chain dehydrogenase reductase Sdr
GYMC61_RS09225	COG0318	PFAM AMP-dependent synthetase and ligase
GYMC61_RS09255	COG0436	Aminotransferase
GYMC61_RS09265	COG0598	Magnesium transport protein CorA
GYMC61_RS09295	COG1408	metallophosphoesterase
GYMC61_RS09300	COG1028	Short-chain dehydrogenase reductase Sdr
GYMC61_RS09305	COG2200	EAL domain
GYMC61_RS09320	COG0517	IMP dehydrogenase activity
GYMC61_RS09325	COG2171	N-acyltransferase activity
GYMC61_RS09330	COG1473	amidohydrolase
GYMC61_RS09340	COG0569	domain protein
GYMC61_RS09345	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GYMC61_RS09355	COG0561	phosphatase activity
GYMC61_RS09400	COG1982	Orn Lys Arg decarboxylase major
GYMC61_RS09415	COG0483	inositol monophosphate 1-phosphatase activity
GYMC61_RS09420	COG1217	gtp-binding protein TYPA
GYMC61_RS09435	COG4896	Protein conserved in bacteria
GYMC61_RS09445	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GYMC61_RS09450	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GYMC61_RS09455	COG4838	Belongs to the UPF0358 family
GYMC61_RS09460	COG0772	Belongs to the SEDS family
GYMC61_RS09465	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GYMC61_RS09470	COG1612	heme a metabolic process
GYMC61_RS09475	COG0109	protoheme IX farnesyltransferase activity
GYMC61_RS09500	COG3336	cytochrome c oxidase
GYMC61_RS09520	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GYMC61_RS09525	COG2340	Cysteine-rich secretory protein family
GYMC61_RS09545	COG3679	Belongs to the UPF0342 family
GYMC61_RS09550	COG4471	UPF0298 protein
GYMC61_RS09560	COG0742	ribosomal rna small subunit methyltransferase
GYMC61_RS09565	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GYMC61_RS09570	COG3314	Sporulation integral membrane protein YlbJ
GYMC61_RS09575	COG1752	Esterase of the alpha-beta hydrolase superfamily
GYMC61_RS09580	COG3480	Lon protease (S16) C-terminal proteolytic domain
GYMC61_RS09585	COG1323	Belongs to the UPF0348 family
GYMC61_RS09590	COG1399	metal-binding, possibly nucleic acid-binding protein
GYMC61_RS09595	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GYMC61_RS09600	COG1024	Enoyl-CoA hydratase
GYMC61_RS09610	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GYMC61_RS09620	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GYMC61_RS09625	COG0275	rRNA processing
GYMC61_RS09630	COG4839	cell division protein FtsL
GYMC61_RS09635	COG0768	penicillin binding
GYMC61_RS09640	COG0768	penicillin binding
GYMC61_RS09645	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GYMC61_RS09655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GYMC61_RS09660	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GYMC61_RS09665	COG0772	Belongs to the SEDS family
GYMC61_RS09670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GYMC61_RS09675	COG3879	Bacterial protein of unknown function (DUF881)
GYMC61_RS09680	COG3879	Bacterial protein of unknown function (DUF881)
GYMC61_RS09685	COG3856	small basic protein
GYMC61_RS09690	COG0849	cell division
GYMC61_RS09695	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GYMC61_RS09705	COG1191	sigma factor activity
GYMC61_RS09710	COG1191	sigma factor activity
GYMC61_RS09715	COG1873	PFAM PRC-barrel domain
GYMC61_RS09725	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GYMC61_RS09730	COG1799	cell septum assembly
GYMC61_RS09735	COG0762	integral membrane protein
GYMC61_RS09740	COG2302	S4 RNA-binding domain
GYMC61_RS09745	COG3599	regulation of cell shape
GYMC61_RS09750	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GYMC61_RS09755	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GYMC61_RS09760	COG0564	pseudouridine synthase activity
GYMC61_RS09775	COG0540	Belongs to the ATCase OTCase family
GYMC61_RS09780	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GYMC61_RS09800	COG0167	dihydroorotate dehydrogenase activity
GYMC61_RS09805	COG0284	orotidine-5'-phosphate decarboxylase activity
GYMC61_RS09855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GYMC61_RS09870	COG3209	COG3209 Rhs family protein
GYMC61_RS09895	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GYMC61_RS09900	COG1561	YicC-like family, N-terminal region
GYMC61_RS09905	COG2052	Domain of unknown function (DUF370)
GYMC61_RS09910	COG0194	GDP metabolic process
GYMC61_RS09915	COG1758	RNA polymerase activity
GYMC61_RS09920	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GYMC61_RS09925	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GYMC61_RS09930	COG0242	peptide deformylase activity
GYMC61_RS09935	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GYMC61_RS09940	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GYMC61_RS09940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GYMC61_RS09945	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GYMC61_RS09950	COG0631	protein serine/threonine phosphatase activity
GYMC61_RS09955	COG0515	serine threonine protein kinase
GYMC61_RS09955	COG2815	serine threonine protein kinase
GYMC61_RS09960	COG1162	GTPase activity
GYMC61_RS09965	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GYMC61_RS09970	COG1564	THIamine pyrophosphokinase
GYMC61_RS09980	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GYMC61_RS09985	COG1302	Protein conserved in bacteria
GYMC61_RS09990	COG1461	Dihydroxyacetone kinase
GYMC61_RS09995	COG1760	l-serine dehydratase
GYMC61_RS10000	COG1760	l-serine dehydratase
GYMC61_RS10005	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GYMC61_RS10010	COG2050	protein possibly involved in aromatic compounds catabolism
GYMC61_RS10010	COG1349	DNA-binding transcription factor activity
GYMC61_RS10015	COG0416	fatty acid biosynthetic process
GYMC61_RS10020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GYMC61_RS10025	COG1028	Short-chain dehydrogenase reductase Sdr
GYMC61_RS10030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GYMC61_RS10035	COG0571	ribonuclease III activity
GYMC61_RS10040	COG1196	nuclear chromosome segregation
GYMC61_RS10045	COG0552	protein localization to endoplasmic reticulum
GYMC61_RS10050	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GYMC61_RS10055	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GYMC61_RS10060	COG0228	four-way junction DNA binding
GYMC61_RS10065	COG1837	Belongs to the UPF0109 family
GYMC61_RS10080	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GYMC61_RS10085	COG0336	Belongs to the RNA methyltransferase TrmD family
GYMC61_RS10100	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GYMC61_RS10105	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GYMC61_RS10115	COG2257	FlhB HrpN YscU SpaS Family
GYMC61_RS10120	COG0045	succinate-CoA ligase (ADP-forming) activity
GYMC61_RS10125	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GYMC61_RS10130	COG0758	DNA mediated transformation
GYMC61_RS10135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GYMC61_RS10140	COG4974	Belongs to the 'phage' integrase family
GYMC61_RS10145	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GYMC61_RS10150	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GYMC61_RS10155	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GYMC61_RS10160	COG1815	bacterial-type flagellum-dependent cell motility
GYMC61_RS10165	COG1558	bacterial-type flagellum-dependent cell motility
GYMC61_RS10170	COG1677	Flagellar hook-basal body complex protein FliE
GYMC61_RS10175	COG1766	The M ring may be actively involved in energy transduction
GYMC61_RS10180	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GYMC61_RS10185	COG1317	bacterial-type flagellum organization
GYMC61_RS10190	COG1157	protein secretion by the type III secretion system
GYMC61_RS10195	COG2882	bacterial-type flagellum organization
GYMC61_RS10205	COG3144	bacterial-type flagellum assembly
GYMC61_RS10210	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GYMC61_RS10215	COG4786	Flagellar basal body rod
GYMC61_RS10220	COG1582	Flagellar protein (FlbD)
GYMC61_RS10230	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GYMC61_RS10235	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GYMC61_RS10235	COG1776	CheC inhibitor of MCP methylation
GYMC61_RS10240	COG2201	protein-glutamate methylesterase activity
GYMC61_RS10245	COG3190	flagellar
GYMC61_RS10250	COG1338	Plays a role in the flagellum-specific transport system
GYMC61_RS10255	COG1987	bacterial-type flagellum assembly
GYMC61_RS10260	COG1684	flagellar biosynthetic protein fliR
GYMC61_RS10265	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GYMC61_RS10270	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GYMC61_RS10275	COG1419	protein localization to endoplasmic reticulum
GYMC61_RS10280	COG0455	bacterial-type flagellum organization
GYMC61_RS10285	COG2201	protein-glutamate methylesterase activity
GYMC61_RS10290	COG2198	Histidine kinase
GYMC61_RS10290	COG0643	Histidine kinase
GYMC61_RS10295	COG0835	chemotaxis
GYMC61_RS10300	COG1776	CheC inhibitor of MCP methylation
GYMC61_RS10305	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GYMC61_RS10310	COG1191	sigma factor activity
GYMC61_RS10325	COG0052	Belongs to the universal ribosomal protein uS2 family
GYMC61_RS10330	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GYMC61_RS10335	COG0528	UMP kinase activity
GYMC61_RS10340	COG0233	cytoplasmic translational termination
GYMC61_RS10345	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GYMC61_RS10350	COG4589	Belongs to the CDS family
GYMC61_RS10355	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GYMC61_RS10360	COG0750	zinc metalloprotease
GYMC61_RS10365	COG0442	prolyl-tRNA aminoacylation
GYMC61_RS10370	COG2176	DNA-directed DNA polymerase activity
GYMC61_RS10375	COG0779	Required for maturation of 30S ribosomal subunits
GYMC61_RS10380	COG0195	Participates in both transcription termination and antitermination
GYMC61_RS10385	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GYMC61_RS10390	COG1358	cellular component organization or biogenesis
GYMC61_RS10400	COG1550	Protein conserved in bacteria
GYMC61_RS10405	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GYMC61_RS10410	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GYMC61_RS10415	COG0196	riboflavin kinase activity
GYMC61_RS10420	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GYMC61_RS10425	COG1185	polyribonucleotide nucleotidyltransferase activity
GYMC61_RS10435	COG0726	polysaccharide deacetylase
GYMC61_RS10440	COG0612	Peptidase, M16
GYMC61_RS10445	COG1873	PFAM PRC-barrel domain
GYMC61_RS10450	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GYMC61_RS10455	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GYMC61_RS10460	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GYMC61_RS10465	COG0527	aspartate kinase activity
GYMC61_RS10475	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GYMC61_RS10480	COG0740	serine-type endopeptidase activity
GYMC61_RS10490	COG4980	gas vesicle protein
GYMC61_RS10490	COG1674	ftsk spoiiie
GYMC61_RS10495	COG2188	Transcriptional regulator
GYMC61_RS10500	COG1744	ABC transporter substrate-binding protein PnrA-like
GYMC61_RS10505	COG3845	ABC transporter
GYMC61_RS10510	COG4603	Belongs to the binding-protein-dependent transport system permease family
GYMC61_RS10515	COG1079	Belongs to the binding-protein-dependent transport system permease family
GYMC61_RS10520	COG0612	Peptidase, M16
GYMC61_RS10525	COG0612	Peptidase, M16
GYMC61_RS10530	COG0300	oxidoreductase activity
GYMC61_RS10550	COG1426	Protein conserved in bacteria
GYMC61_RS10555	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GYMC61_RS10560	COG1546	Belongs to the CinA family
GYMC61_RS10560	COG1058	Belongs to the CinA family
GYMC61_RS10565	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GYMC61_RS10575	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GYMC61_RS10580	COG3344	reverse transcriptase
GYMC61_RS10585	COG1418	mRNA catabolic process
GYMC61_RS10590	COG1692	metallophosphoesterase
GYMC61_RS10595	COG2359	stage V sporulation protein S
GYMC61_RS10605	COG0674	pyruvate-flavodoxin oxidoreductase activity
GYMC61_RS10605	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GYMC61_RS10610	COG1013	pyruvate-flavodoxin oxidoreductase activity
GYMC61_RS10615	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GYMC61_RS10620	COG4550	Control of competence regulator ComK, YlbF/YmcA
GYMC61_RS10630	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GYMC61_RS10635	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GYMC61_RS10640	COG3942	CHAP domain
GYMC61_RS10640	COG1388	LysM domain
GYMC61_RS10645	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GYMC61_RS10655	COG0477	Major facilitator Superfamily
GYMC61_RS10660	COG0840	transmembrane signaling receptor activity
GYMC61_RS10665	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GYMC61_RS10670	COG1923	regulation of RNA biosynthetic process
GYMC61_RS10675	COG0464	growth
GYMC61_RS10685	COG1960	acyl-CoA dehydrogenase activity
GYMC61_RS10690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GYMC61_RS10695	COG0318	PFAM AMP-dependent synthetase and ligase
GYMC61_RS10700	COG1250	3-hydroxyacyl-CoA dehydrogenase
GYMC61_RS10705	COG0183	Belongs to the thiolase family
GYMC61_RS10710	COG0697	spore germination
GYMC61_RS10715	COG2860	membrane
GYMC61_RS10720	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GYMC61_RS10725	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GYMC61_RS10730	COG0789	Transcriptional regulator
GYMC61_RS10735	COG0174	glutamine synthetase
GYMC61_RS10740	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GYMC61_RS10745	COG1388	LysM domain
GYMC61_RS10750	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GYMC61_RS10755	COG4224	UPF0291 protein
GYMC61_RS10770	COG3763	UPF0154 protein
GYMC61_RS10775	COG1132	(ABC) transporter
GYMC61_RS10780	COG1132	(ABC) transporter
GYMC61_RS10790	COG0785	Cytochrome C biogenesis protein
GYMC61_RS10795	COG2201	protein-glutamate methylesterase activity
GYMC61_RS10800	COG4846	Membrane protein involved in cytochrome C biogenesis
GYMC61_RS10810	COG1388	LysM domain
GYMC61_RS10810	COG3584	3D domain protein
GYMC61_RS10815	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GYMC61_RS10815	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GYMC61_RS10855	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GYMC61_RS10860	COG0697	spore germination
GYMC61_RS10865	COG0328	RNA-DNA hybrid ribonuclease activity
GYMC61_RS10895	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GYMC61_RS10925	COG0346	lactoylglutathione lyase activity
GYMC61_RS10940	COG0010	Belongs to the arginase family
GYMC61_RS10945	COG4977	sequence-specific DNA binding
GYMC61_RS10945	COG1917	Cupin 2, conserved barrel domain protein
GYMC61_RS10950	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GYMC61_RS10955	COG1228	amidohydrolase
GYMC61_RS10960	COG3314	Sporulation integral membrane protein YlbJ
GYMC61_RS10965	COG1970	mechanosensitive ion channel activity
GYMC61_RS10970	COG2391	methyltransferase activity
GYMC61_RS10975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GYMC61_RS10980	COG2313	pseudouridylate synthase activity
GYMC61_RS10990	COG0653	protein targeting
GYMC61_RS11005	COG3384	dioxygenase
GYMC61_RS11035	COG3620	sequence-specific DNA binding
GYMC61_RS11085	COG0154	amidase activity
GYMC61_RS11100	COG0579	oxidoreductase
GYMC61_RS11110	COG5582	Belongs to the UPF0302 family
GYMC61_RS11115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GYMC61_RS11120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GYMC61_RS11135	COG0393	Putative heavy-metal-binding
GYMC61_RS11140	COG0640	Transcriptional regulator
GYMC61_RS11150	COG0583	DNA-binding transcription factor activity
GYMC61_RS11155	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GYMC61_RS11160	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GYMC61_RS11170	COG1028	Short-chain dehydrogenase reductase Sdr
GYMC61_RS11180	COG1846	Transcriptional regulator
GYMC61_RS11205	COG1953	Uracil, thiamine, allantoin
GYMC61_RS11215	COG0493	'glutamate synthase
GYMC61_RS11220	COG0167	dihydroorotate dehydrogenase activity
GYMC61_RS11235	COG3835	regulator
GYMC61_RS11240	COG1012	belongs to the aldehyde dehydrogenase family
GYMC61_RS11245	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GYMC61_RS11255	COG0604	alcohol dehydrogenase
GYMC61_RS11260	COG2376	Dihydroxyacetone kinase
GYMC61_RS11270	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GYMC61_RS11275	COG0583	DNA-binding transcription factor activity
GYMC61_RS11280	COG0067	glutamate synthase
GYMC61_RS11280	COG0070	glutamate synthase
GYMC61_RS11280	COG0069	glutamate synthase activity
GYMC61_RS11285	COG0493	'glutamate synthase
GYMC61_RS11290	COG0671	phosphoesterase, PA-phosphatase related
GYMC61_RS11310	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GYMC61_RS11325	COG4821	SIS domain
GYMC61_RS11330	COG1737	Transcriptional regulator
GYMC61_RS11335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GYMC61_RS11335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GYMC61_RS11335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GYMC61_RS11340	COG0383	alpha-mannosidase activity
GYMC61_RS11345	COG2340	Cysteine-rich secretory protein family
GYMC61_RS11370	COG3853	Toxic anion resistance protein (TelA)
GYMC61_RS11390	COG0004	ammonium transporteR
GYMC61_RS11410	COG2271	Major facilitator Superfamily
GYMC61_RS11415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GYMC61_RS11430	COG0179	Fumarylacetoacetate (FAA) hydrolase
GYMC61_RS11475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GYMC61_RS11480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GYMC61_RS11485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GYMC61_RS11490	COG1120	ATPase activity
GYMC61_RS11520	COG0406	alpha-ribazole phosphatase activity
GYMC61_RS11525	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GYMC61_RS11530	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GYMC61_RS11540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GYMC61_RS11545	COG2508	Transcriptional regulator
GYMC61_RS11550	COG1250	3-hydroxyacyl-CoA dehydrogenase
GYMC61_RS11555	COG1024	Enoyl-CoA hydratase
GYMC61_RS11560	COG2814	Major facilitator Superfamily
GYMC61_RS11570	COG0318	PFAM AMP-dependent synthetase and ligase
GYMC61_RS11575	COG0183	Belongs to the thiolase family
GYMC61_RS11595	COG0179	Fumarylacetoacetate (FAA) hydrolase
GYMC61_RS11635	COG3971	2-oxopent-4-enoate hydratase activity
GYMC61_RS11675	COG1172	Belongs to the binding-protein-dependent transport system permease family
GYMC61_RS11680	COG0411	ABC transporter
GYMC61_RS11690	COG1012	belongs to the aldehyde dehydrogenase family
GYMC61_RS11695	COG1414	Transcriptional regulator
GYMC61_RS11700	COG1414	Transcriptional regulator
GYMC61_RS11720	COG0179	Fumarylacetoacetate (FAA) hydrolase
GYMC61_RS11735	COG2814	Major facilitator Superfamily
GYMC61_RS11750	COG4555	ABC transporter
GYMC61_RS11775	COG0318	PFAM AMP-dependent synthetase and ligase
GYMC61_RS11780	COG1960	acyl-CoA dehydrogenase activity
GYMC61_RS11795	COG0745	RESPONSE REGULATOR receiver
GYMC61_RS11800	COG5002	protein histidine kinase activity
GYMC61_RS11805	COG2135	peptidase activity
GYMC61_RS11820	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GYMC61_RS11820	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GYMC61_RS11825	COG0456	acetyltransferase
GYMC61_RS11830	COG1414	Transcriptional regulator
GYMC61_RS11835	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GYMC61_RS11840	COG1984	allophanate hydrolase subunit 2
GYMC61_RS11845	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GYMC61_RS11860	COG0318	PFAM AMP-dependent synthetase and ligase
GYMC61_RS11875	COG0463	Glycosyl transferase, family 2
GYMC61_RS11880	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GYMC61_RS11885	COG0351	phosphomethylpyrimidine kinase
GYMC61_RS11890	COG0352	thiamine-phosphate diphosphorylase activity
GYMC61_RS11895	COG3594	Acyltransferase
GYMC61_RS11915	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GYMC61_RS11920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GYMC61_RS11930	COG5577	PFAM Coat F domain
GYMC61_RS11950	COG3852	Histidine kinase
GYMC61_RS11955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GYMC61_RS11960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GYMC61_RS11970	COG0670	Belongs to the BI1 family
GYMC61_RS11975	COG3622	Belongs to the hyi family
GYMC61_RS11980	COG2084	Dehydrogenase
GYMC61_RS11990	COG0277	FAD linked oxidase domain protein
GYMC61_RS11995	COG0247	lactate metabolic process
GYMC61_RS12000	COG0277	FAD linked oxidase domain protein
GYMC61_RS12005	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GYMC61_RS12010	COG0281	malic enzyme
GYMC61_RS12020	COG1414	Transcriptional regulator
GYMC61_RS12030	COG1205	dead DEAH box helicase
GYMC61_RS12030	COG1111	helicase
GYMC61_RS12035	COG3359	exonuclease
GYMC61_RS12060	COG3599	regulation of cell shape
GYMC61_RS12065	COG0116	Belongs to the methyltransferase superfamily
GYMC61_RS12070	COG1199	ATP-dependent helicase activity
GYMC61_RS12075	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GYMC61_RS12080	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GYMC61_RS12085	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GYMC61_RS12095	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GYMC61_RS12110	COG3424	synthase
GYMC61_RS12115	COG1755	Isoprenylcysteine carboxyl methyltransferase
GYMC61_RS12120	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GYMC61_RS12140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GYMC61_RS12155	COG0824	Thioesterase
GYMC61_RS12165	COG2050	protein possibly involved in aromatic compounds catabolism
GYMC61_RS12170	COG4841	protein insertion into membrane
GYMC61_RS12190	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GYMC61_RS12195	COG4479	Belongs to the UPF0346 family
GYMC61_RS12225	COG0813	purine-nucleoside phosphorylase activity
GYMC61_RS12230	COG1876	peptidase activity
GYMC61_RS12235	COG2226	methyltransferase
GYMC61_RS12240	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GYMC61_RS12245	COG0598	Magnesium transport protein CorA
GYMC61_RS12250	COG2962	Rard protein
GYMC61_RS12260	COG0534	Mate efflux family protein
GYMC61_RS12265	COG3852	Histidine kinase
GYMC61_RS12270	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GYMC61_RS12275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GYMC61_RS12295	COG1309	transcriptional regulator
GYMC61_RS12300	COG1960	acyl-CoA dehydrogenase activity
GYMC61_RS12305	COG0318	PFAM AMP-dependent synthetase and ligase
GYMC61_RS12310	COG0439	Biotin carboxylase
GYMC61_RS12315	COG0511	ligase activity, forming carbon-carbon bonds
GYMC61_RS12320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GYMC61_RS12325	COG1024	Enoyl-CoA hydratase
GYMC61_RS12330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GYMC61_RS12335	COG1846	Transcriptional regulator
GYMC61_RS12340	COG1566	PFAM secretion protein HlyD family protein
GYMC61_RS12345	COG2814	Major facilitator Superfamily
GYMC61_RS12350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GYMC61_RS12370	COG2205	protein histidine kinase activity
GYMC61_RS12390	COG2323	membrane
GYMC61_RS12395	COG1725	Transcriptional regulator
GYMC61_RS12400	COG1131	(ABC) transporter
GYMC61_RS12415	COG0697	spore germination
GYMC61_RS12425	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GYMC61_RS12430	COG2208	phosphoserine phosphatase activity
GYMC61_RS12435	COG3290	protein histidine kinase activity
GYMC61_RS12445	COG1132	(ABC) transporter
GYMC61_RS12450	COG1132	(ABC) transporter
GYMC61_RS12465	COG2258	MOSC domain
GYMC61_RS12470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GYMC61_RS12495	COG0730	response to heat
GYMC61_RS12505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GYMC61_RS12520	COG1131	(ABC) transporter
GYMC61_RS12525	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GYMC61_RS12560	COG2337	Toxic component of a toxin-antitoxin (TA) module
GYMC61_RS12570	COG1741	Belongs to the pirin family
GYMC61_RS12575	COG0778	Nitroreductase
GYMC61_RS12580	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GYMC61_RS12585	COG1960	acyl-CoA dehydrogenase activity
GYMC61_RS12595	COG2030	dehydratase
GYMC61_RS12605	COG0183	Belongs to the thiolase family
GYMC61_RS12615	COG0559	Belongs to the binding-protein-dependent transport system permease family
GYMC61_RS12645	COG0697	spore germination
GYMC61_RS12680	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GYMC61_RS12685	COG1119	ATPase activity
GYMC61_RS12705	COG1028	Short-chain dehydrogenase reductase Sdr
GYMC61_RS12710	COG1028	Short-chain dehydrogenase reductase Sdr
GYMC61_RS12715	COG1024	Enoyl-CoA hydratase
GYMC61_RS12720	COG0515	serine threonine protein kinase
GYMC61_RS12730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GYMC61_RS12730	COG0551	DNA topoisomerase type I activity
GYMC61_RS12735	COG5002	protein histidine kinase activity
GYMC61_RS12740	COG0745	RESPONSE REGULATOR receiver
GYMC61_RS12750	COG1388	LysM domain
GYMC61_RS12755	COG3402	PFAM membrane-flanked domain
GYMC61_RS12765	COG1279	arginine transmembrane transporter activity
GYMC61_RS12770	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GYMC61_RS12830	COG2404	hydrolase activity, acting on ester bonds
GYMC61_RS12835	COG4548	von Willebrand factor, type A
GYMC61_RS12840	COG0714	Associated with various cellular activities
GYMC61_RS12850	COG0788	formyltetrahydrofolate deformylase activity
GYMC61_RS12855	COG1017	nitric oxide dioxygenase activity
GYMC61_RS12855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GYMC61_RS12860	COG1959	2 iron, 2 sulfur cluster binding
GYMC61_RS12865	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GYMC61_RS12870	COG1960	acyl-CoA dehydrogenase activity
GYMC61_RS12875	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GYMC61_RS12875	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GYMC61_RS12890	COG1757	Na H antiporter
GYMC61_RS12895	COG2188	Transcriptional regulator
GYMC61_RS12900	COG0366	Alpha amylase catalytic
GYMC61_RS12905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GYMC61_RS12905	COG1263	PTS System
GYMC61_RS12920	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GYMC61_RS12925	COG0187	DNA topoisomerase II activity
GYMC61_RS12930	COG1832	CoA-binding protein
GYMC61_RS12940	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GYMC61_RS12950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GYMC61_RS12955	COG2608	mercury ion transmembrane transporter activity
GYMC61_RS13000	COG3647	Membrane
GYMC61_RS13010	COG0385	Bile acid
GYMC61_RS13015	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GYMC61_RS13035	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GYMC61_RS13040	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GYMC61_RS13045	COG2195	Cleaves the N-terminal amino acid of tripeptides
GYMC61_RS13055	COG0004	ammonium transporteR
GYMC61_RS13060	COG0347	Belongs to the P(II) protein family
GYMC61_RS13075	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GYMC61_RS13080	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GYMC61_RS13080	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GYMC61_RS13090	COG2755	lipolytic protein G-D-S-L family
GYMC61_RS13095	COG1999	signal sequence binding
GYMC61_RS13100	COG1307	EDD domain protein, DegV family
GYMC61_RS13110	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GYMC61_RS13120	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GYMC61_RS13125	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GYMC61_RS13140	COG0436	Aminotransferase
GYMC61_RS13150	COG0494	nUDIX hydrolase
GYMC61_RS13160	COG1413	lyase activity
GYMC61_RS13165	COG0386	Belongs to the glutathione peroxidase family
GYMC61_RS13175	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GYMC61_RS13180	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GYMC61_RS13190	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GYMC61_RS13200	COG1492	cobalamin metabolic process
GYMC61_RS13230	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
GYMC61_RS13255	COG1122	ATPase activity
GYMC61_RS13260	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GYMC61_RS13265	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
GYMC61_RS13270	COG0310	cobalt ion transport
GYMC61_RS13290	COG0584	glycerophosphoryl diester phosphodiesterase
GYMC61_RS13295	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GYMC61_RS13300	COG4989	oxidoreductase activity
GYMC61_RS13305	COG1164	Oligoendopeptidase f
GYMC61_RS13310	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GYMC61_RS13315	COG1335	isochorismatase
GYMC61_RS13320	COG0706	membrane insertase activity
GYMC61_RS13345	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GYMC61_RS13350	COG1140	nitrate reductase beta subunit
GYMC61_RS13355	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GYMC61_RS13360	COG2181	nitrate reductase activity
GYMC61_RS13365	COG1587	Uroporphyrinogen-III synthase
GYMC61_RS13380	COG5002	protein histidine kinase activity
GYMC61_RS13385	COG0024	Methionine aminopeptidase
GYMC61_RS13390	COG0432	Pfam Uncharacterised protein family UPF0047
GYMC61_RS13400	COG3689	TIGRFAM TIGR03943 family protein
GYMC61_RS13405	COG0701	Predicted permease
GYMC61_RS13410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GYMC61_RS13410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GYMC61_RS13410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GYMC61_RS13415	COG1105	Belongs to the carbohydrate kinase PfkB family
GYMC61_RS13420	COG1349	DNA-binding transcription factor activity
GYMC61_RS13425	COG2199	diguanylate cyclase activity
GYMC61_RS13425	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GYMC61_RS13460	COG0385	Bile acid
GYMC61_RS13470	COG1757	Na H antiporter
GYMC61_RS13475	COG1408	metallophosphoesterase
GYMC61_RS13480	COG0726	polysaccharide deacetylase
GYMC61_RS13490	COG2188	Transcriptional regulator
GYMC61_RS13495	COG2723	6-phospho-beta-galactosidase activity
GYMC61_RS13500	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GYMC61_RS13505	COG1447	Phosphotransferase system cellobiose-specific component IIA
GYMC61_RS13510	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GYMC61_RS13515	COG0789	Transcriptional regulator
GYMC61_RS13525	COG2223	nitrite transmembrane transporter activity
GYMC61_RS13530	COG0243	molybdopterin cofactor binding
GYMC61_RS13535	COG2146	nitrite reductase [NAD(P)H] activity
GYMC61_RS13540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GYMC61_RS13545	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GYMC61_RS13555	COG1454	alcohol dehydrogenase
GYMC61_RS13565	COG3829	transcription factor binding
GYMC61_RS13565	COG3290	protein histidine kinase activity
GYMC61_RS13585	COG1070	Carbohydrate kinase
GYMC61_RS13590	COG2115	Belongs to the xylose isomerase family
GYMC61_RS13635	COG5578	integral membrane protein
GYMC61_RS13640	COG1028	Short-chain dehydrogenase reductase Sdr
GYMC61_RS13650	COG1904	glucuronate isomerase
GYMC61_RS13665	COG1802	Transcriptional regulator
GYMC61_RS13670	COG1304	FMN binding
GYMC61_RS13675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GYMC61_RS13690	COG0395	ABC-type sugar transport system, permease component
GYMC61_RS13695	COG4209	transmembrane transport
GYMC61_RS13730	COG1175	transmembrane transport
GYMC61_RS13745	COG2207	Transcriptional regulator
GYMC61_RS13750	COG2972	Histidine kinase
GYMC61_RS13765	COG0647	UMP catabolic process
GYMC61_RS13785	COG3534	alpha-L-arabinofuranosidase
GYMC61_RS13790	COG3507	Belongs to the glycosyl hydrolase 43 family
GYMC61_RS13795	COG0395	ABC-type sugar transport system, permease component
GYMC61_RS13800	COG1175	transmembrane transport
GYMC61_RS13805	COG1653	transport
GYMC61_RS13815	COG3345	alpha-galactosidase
GYMC61_RS13825	COG1069	ribulokinase activity
GYMC61_RS13850	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GYMC61_RS13860	COG4166	transmembrane transport
GYMC61_RS13865	COG4608	Belongs to the ABC transporter superfamily
GYMC61_RS13870	COG0444	Belongs to the ABC transporter superfamily
GYMC61_RS13875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GYMC61_RS13880	COG0601	transmembrane transport
GYMC61_RS13885	COG2362	D-Aminopeptidase
GYMC61_RS13895	COG1228	amidohydrolase
GYMC61_RS13900	COG1024	Enoyl-CoA hydratase
GYMC61_RS13905	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GYMC61_RS13910	COG1012	belongs to the aldehyde dehydrogenase family
GYMC61_RS13920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GYMC61_RS13925	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GYMC61_RS13940	COG1012	belongs to the aldehyde dehydrogenase family
GYMC61_RS13955	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GYMC61_RS13970	COG0456	acetyltransferase
GYMC61_RS13990	COG0830	nickel cation binding
GYMC61_RS13995	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GYMC61_RS14000	COG0804	urea catabolic process
GYMC61_RS14005	COG0832	Belongs to the urease beta subunit family
GYMC61_RS14010	COG0831	urea catabolic process
GYMC61_RS14020	COG0411	ABC transporter
GYMC61_RS14040	COG0840	transmembrane signaling receptor activity
GYMC61_RS14055	COG1609	Transcriptional regulator
GYMC61_RS14065	COG0679	Auxin Efflux Carrier
GYMC61_RS14070	COG4565	transcriptional regulatory protein
GYMC61_RS14075	COG3290	protein histidine kinase activity
GYMC61_RS14100	COG0246	Mannitol dehydrogenase
GYMC61_RS14110	COG3711	transcriptional antiterminator
GYMC61_RS14135	COG1012	belongs to the aldehyde dehydrogenase family
GYMC61_RS14150	COG0667	Aldo Keto reductase
GYMC61_RS14165	COG0765	amino acid transport
GYMC61_RS14170	COG0765	amino acid transport
GYMC61_RS14175	COG4191	Histidine kinase
GYMC61_RS14180	COG0784	Response regulator, receiver
GYMC61_RS14190	COG1263	PTS System
GYMC61_RS14190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GYMC61_RS14195	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GYMC61_RS14200	COG1737	Transcriptional regulator
GYMC61_RS14210	COG1028	Short-chain dehydrogenase reductase Sdr
GYMC61_RS14215	COG2154	pterin-4-alpha-carbinolamine dehydratase
GYMC61_RS14230	COG1657	PFAM Prenyltransferase squalene oxidase
GYMC61_RS14245	COG2755	lipolytic protein G-D-S-L family
GYMC61_RS14250	COG0385	Bile acid
GYMC61_RS14255	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GYMC61_RS14270	COG1024	Enoyl-CoA hydratase
GYMC61_RS14285	COG2151	metal-sulfur cluster biosynthetic enzyme
GYMC61_RS14310	COG1012	belongs to the aldehyde dehydrogenase family
GYMC61_RS14330	COG3764	Sortase (surface protein transpeptidase)
GYMC61_RS14355	COG1175	transmembrane transport
GYMC61_RS14360	COG3842	ATPase activity
GYMC61_RS14365	COG3104	oligopeptide transport
GYMC61_RS14385	COG0022	dehydrogenase e1 component
GYMC61_RS14395	COG3842	ATPase activity
GYMC61_RS14400	COG4120	Belongs to the binding-protein-dependent transport system permease family
GYMC61_RS14420	COG3327	negative regulation of DNA-templated transcription, initiation
GYMC61_RS14425	COG0183	Belongs to the thiolase family
GYMC61_RS14430	COG1250	3-hydroxyacyl-CoA dehydrogenase
GYMC61_RS14435	COG1012	belongs to the aldehyde dehydrogenase family
GYMC61_RS14440	COG1024	Enoyl-CoA hydratase
GYMC61_RS14445	COG1024	Enoyl-CoA hydratase
GYMC61_RS14455	COG2151	metal-sulfur cluster biosynthetic enzyme
GYMC61_RS14470	COG3396	Phenylacetate-CoA oxygenase
GYMC61_RS14475	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GYMC61_RS14480	COG0129	dihydroxy-acid dehydratase activity
GYMC61_RS14485	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GYMC61_RS14490	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GYMC61_RS14500	COG2246	polysaccharide biosynthetic process
GYMC61_RS14505	COG0463	Glycosyl transferase, family 2
GYMC61_RS14510	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GYMC61_RS14525	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GYMC61_RS14530	COG0710	3-dehydroquinate dehydratase activity
GYMC61_RS14535	COG0561	phosphatase activity
GYMC61_RS14560	COG0730	response to heat
GYMC61_RS14570	COG0425	Belongs to the sulfur carrier protein TusA family
GYMC61_RS14570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GYMC61_RS14575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GYMC61_RS14585	COG2210	Belongs to the sulfur carrier protein TusA family
GYMC61_RS14590	COG0425	Belongs to the sulfur carrier protein TusA family
GYMC61_RS14595	COG1937	Protein conserved in bacteria
GYMC61_RS14605	COG2226	methyltransferase
GYMC61_RS14610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GYMC61_RS14610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GYMC61_RS14620	COG2210	Belongs to the sulfur carrier protein TusA family
GYMC61_RS14625	COG3858	chitin binding
GYMC61_RS14625	COG1388	LysM domain
GYMC61_RS14635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GYMC61_RS14650	COG2814	Major facilitator Superfamily
GYMC61_RS14655	COG1294	oxidase, subunit
GYMC61_RS14660	COG1271	oxidase subunit
GYMC61_RS14665	COG2197	response regulator
GYMC61_RS14675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GYMC61_RS14685	COG0446	pyridine nucleotide-disulphide oxidoreductase
GYMC61_RS14705	COG2814	Major facilitator Superfamily
GYMC61_RS14710	COG1664	Polymer-forming cytoskeletal
GYMC61_RS14715	COG1664	Polymer-forming cytoskeletal
GYMC61_RS14720	COG0789	Transcriptional regulator
GYMC61_RS14725	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GYMC61_RS14740	COG4821	SIS domain
GYMC61_RS14780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GYMC61_RS14810	COG4336	lyase activity
GYMC61_RS14815	COG1061	Type III restriction enzyme res subunit
GYMC61_RS14850	COG1082	Xylose isomerase domain protein TIM barrel
GYMC61_RS14855	COG0673	inositol 2-dehydrogenase activity
GYMC61_RS14865	COG0673	inositol 2-dehydrogenase activity
GYMC61_RS14870	COG1609	Transcriptional regulator
GYMC61_RS14885	COG0477	Major facilitator Superfamily
GYMC61_RS14890	COG1012	belongs to the aldehyde dehydrogenase family
GYMC61_RS14890	COG2030	dehydratase
GYMC61_RS14905	COG1653	transport
GYMC61_RS14915	COG2066	Belongs to the glutaminase family
GYMC61_RS14955	COG0156	8-amino-7-oxononanoate synthase activity
GYMC61_RS14970	COG4377	Putative membrane peptidase family (DUF2324)
GYMC61_RS14980	COG0640	Transcriptional regulator
GYMC61_RS14990	COG0318	PFAM AMP-dependent synthetase and ligase
GYMC61_RS15025	COG1131	(ABC) transporter
GYMC61_RS15060	COG1280	lysine exporter protein (LysE YggA)
GYMC61_RS15115	COG1285	pathogenesis
GYMC61_RS15140	COG1247	-acetyltransferase
GYMC61_RS15145	COG2814	Major facilitator Superfamily
GYMC61_RS15155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GYMC61_RS15170	COG0166	Belongs to the GPI family
GYMC61_RS15175	COG1979	alcohol dehydrogenase
GYMC61_RS15180	COG2155	Conserved Protein
GYMC61_RS15185	COG1098	S1 RNA binding domain
GYMC61_RS15190	COG0436	Aminotransferase
GYMC61_RS15195	COG1522	sequence-specific DNA binding
GYMC61_RS15205	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GYMC61_RS15210	COG2032	superoxide dismutase activity
GYMC61_RS15220	COG5018	Exonuclease
GYMC61_RS15240	COG1268	BioY protein
GYMC61_RS15245	COG0306	phosphate transporter
GYMC61_RS15250	COG1392	Phosphate transport regulator
GYMC61_RS15255	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GYMC61_RS15265	COG3584	3D domain protein
GYMC61_RS15280	COG1252	NADH dehydrogenase
GYMC61_RS15285	COG0492	ferredoxin-NADP+ reductase activity
GYMC61_RS15290	COG5416	Lipopolysaccharide assembly protein A domain
GYMC61_RS15295	COG0316	Belongs to the HesB IscA family
GYMC61_RS15300	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GYMC61_RS15305	COG4844	belongs to the
GYMC61_RS15310	COG1252	NADH dehydrogenase
GYMC61_RS15315	COG4837	Protein of unknown function (DUF1462)
GYMC61_RS15320	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GYMC61_RS15335	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GYMC61_RS15340	COG0460	homoserine dehydrogenase
GYMC61_RS15350	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GYMC61_RS15355	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GYMC61_RS15360	COG0647	UMP catabolic process
GYMC61_RS15365	COG2445	Protein of unknown function DUF86
GYMC61_RS15380	COG4470	Protein conserved in bacteria
GYMC61_RS15390	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GYMC61_RS15395	COG0739	heme binding
GYMC61_RS15410	COG0411	ABC transporter
GYMC61_RS15435	COG3377	Domain of unknown function (DUF1805)
GYMC61_RS15440	COG0737	Belongs to the 5'-nucleotidase family
GYMC61_RS15445	COG0730	response to heat
GYMC61_RS15450	COG1801	Protein of unknown function DUF72
GYMC61_RS15455	COG1280	lysine exporter protein (LysE YggA)
GYMC61_RS15490	COG0719	Fe-S assembly protein
GYMC61_RS15495	COG0822	iron-sulfur transferase activity
GYMC61_RS15500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GYMC61_RS15505	COG0719	Fe-S assembly protein
GYMC61_RS15510	COG0396	ATPase activity
GYMC61_RS15515	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GYMC61_RS15525	COG1464	Belongs to the NlpA lipoprotein family
GYMC61_RS15530	COG2011	ABC-type metal ion transport system permease component
GYMC61_RS15535	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GYMC61_RS15545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GYMC61_RS15550	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GYMC61_RS15560	COG0509	glycine decarboxylation via glycine cleavage system
GYMC61_RS15565	COG1393	Belongs to the ArsC family
GYMC61_RS15570	COG1960	acyl-CoA dehydrogenase activity
GYMC61_RS15575	COG0183	Belongs to the thiolase family
GYMC61_RS15580	COG1250	3-hydroxyacyl-CoA dehydrogenase
GYMC61_RS15580	COG1024	Enoyl-CoA hydratase
GYMC61_RS15585	COG0506	proline dehydrogenase activity
GYMC61_RS15595	COG5577	PFAM Coat F domain
GYMC61_RS15605	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GYMC61_RS15610	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GYMC61_RS15620	COG0469	pyruvate kinase activity
GYMC61_RS15635	COG0410	ABC transporter
GYMC61_RS15665	COG1012	belongs to the aldehyde dehydrogenase family
GYMC61_RS15685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GYMC61_RS15700	COG0583	DNA-binding transcription factor activity
GYMC61_RS15705	COG3546	catalase activity
GYMC61_RS15720	COG2197	response regulator
GYMC61_RS15755	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GYMC61_RS15760	COG0557	exoribonuclease II activity
GYMC61_RS15770	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GYMC61_RS15780	COG2272	Belongs to the type-B carboxylesterase lipase family
GYMC61_RS15800	COG0148	phosphopyruvate hydratase activity
GYMC61_RS15810	COG0149	triose-phosphate isomerase activity
GYMC61_RS15815	COG0126	phosphoglycerate kinase activity
GYMC61_RS15835	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GYMC61_RS15860	COG0740	serine-type endopeptidase activity
GYMC61_RS15865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GYMC61_RS15870	COG1481	regulation of sporulation
GYMC61_RS15875	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GYMC61_RS15880	COG1660	Displays ATPase and GTPase activities
GYMC61_RS15885	COG1051	belongs to the nudix hydrolase family
GYMC61_RS15890	COG0492	ferredoxin-NADP+ reductase activity
GYMC61_RS15895	COG0457	Tetratricopeptide repeat
GYMC61_RS15900	COG0140	phosphoribosyl-ATP diphosphatase activity
GYMC61_RS15900	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GYMC61_RS15905	COG0107	imidazoleglycerol-phosphate synthase activity
GYMC61_RS15910	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GYMC61_RS15915	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GYMC61_RS15920	COG0131	Imidazoleglycerol-phosphate dehydratase
GYMC61_RS15925	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GYMC61_RS15930	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GYMC61_RS15935	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GYMC61_RS15960	COG3344	reverse transcriptase
GYMC61_RS15975	COG0110	maltose O-acetyltransferase activity
GYMC61_RS15980	COG0546	phosphoglycolate phosphatase activity
GYMC61_RS15985	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GYMC61_RS15990	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GYMC61_RS15995	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GYMC61_RS16000	COG1950	PFAM Membrane protein of
GYMC61_RS16010	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GYMC61_RS16015	COG0556	nucleotide-excision repair
GYMC61_RS16020	COG4897	Protein conserved in bacteria
GYMC61_RS16025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GYMC61_RS16030	COG0789	Transcriptional regulator
GYMC61_RS16040	COG0463	Glycosyl transferase, family 2
GYMC61_RS16045	COG3409	Peptidoglycan-binding domain 1 protein
GYMC61_RS16045	COG0793	Belongs to the peptidase S41A family
GYMC61_RS16050	COG1741	Belongs to the pirin family
GYMC61_RS16080	COG0739	heme binding
GYMC61_RS16085	COG2177	Part of the ABC transporter FtsEX involved in
GYMC61_RS16090	COG2884	Cell division ATP-binding protein ftsE
GYMC61_RS16100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GYMC61_RS16115	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GYMC61_RS16120	COG0653	protein targeting
GYMC61_RS16145	COG1516	flagellar protein fliS
GYMC61_RS16150	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GYMC61_RS16155	COG1334	flagellar protein FlaG
GYMC61_RS16175	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GYMC61_RS16180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GYMC61_RS16185	COG2089	acid synthase
GYMC61_RS16200	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
GYMC61_RS16215	COG0562	UDP-galactopyranose mutase
GYMC61_RS16230	COG0463	Glycosyl transferase, family 2
GYMC61_RS16230	COG1216	Glycosyl transferase, family 2
GYMC61_RS16250	COG1086	Polysaccharide biosynthesis protein
GYMC61_RS16260	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GYMC61_RS16265	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GYMC61_RS16270	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GYMC61_RS16280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GYMC61_RS16285	COG1256	bacterial-type flagellum assembly
GYMC61_RS16285	COG4786	Flagellar basal body rod
GYMC61_RS16305	COG1728	Protein conserved in bacteria
GYMC61_RS16310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GYMC61_RS16330	COG1040	competence protein
GYMC61_RS16335	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GYMC61_RS16340	COG1307	EDD domain protein, DegV family
GYMC61_RS16345	COG2197	response regulator
GYMC61_RS16350	COG4585	Histidine kinase
GYMC61_RS16355	COG1739	Uncharacterized protein family UPF0029
GYMC61_RS16360	COG1316	TRANSCRIPTIONal
GYMC61_RS16365	COG0860	N-Acetylmuramoyl-L-alanine amidase
GYMC61_RS16375	COG2247	cell wall binding repeat
GYMC61_RS16375	COG2385	sporulation resulting in formation of a cellular spore
GYMC61_RS16390	COG0438	transferase activity, transferring glycosyl groups
GYMC61_RS16425	COG0673	inositol 2-dehydrogenase activity
GYMC61_RS16440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GYMC61_RS16445	COG0653	protein targeting
GYMC61_RS16455	COG0793	Belongs to the peptidase S41A family
GYMC61_RS16455	COG3409	Peptidoglycan-binding domain 1 protein
GYMC61_RS16505	COG0737	Belongs to the 5'-nucleotidase family
GYMC61_RS16565	COG1388	LysM domain
GYMC61_RS16565	COG0791	NLP P60 protein
GYMC61_RS16580	COG0629	single-stranded DNA binding
GYMC61_RS16590	COG3764	Sortase (surface protein transpeptidase)
GYMC61_RS16605	COG0527	aspartate kinase activity
GYMC61_RS16620	COG1012	belongs to the aldehyde dehydrogenase family
GYMC61_RS16630	COG0477	Major facilitator Superfamily
GYMC61_RS16635	COG1309	transcriptional regulator
GYMC61_RS16645	COG1940	carbohydrate kinase activity
GYMC61_RS16655	COG1175	transmembrane transport
GYMC61_RS16665	COG2207	Transcriptional regulator
GYMC61_RS16665	COG4753	response regulator
GYMC61_RS16665	COG2207	Transcriptional regulator
GYMC61_RS16665	COG4753	response regulator
GYMC61_RS16670	COG2972	Histidine kinase
GYMC61_RS16685	COG1486	melibiose metabolic process
GYMC61_RS16705	COG1136	(ABC) transporter
GYMC61_RS16705	COG0577	efflux transmembrane transporter activity
GYMC61_RS16715	COG0277	FAD linked oxidase domain protein
GYMC61_RS16735	COG0346	lactoylglutathione lyase activity
GYMC61_RS16740	COG0673	inositol 2-dehydrogenase activity
GYMC61_RS16750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GYMC61_RS16755	COG0798	PFAM Bile acid sodium symporter
GYMC61_RS16760	COG0640	Transcriptional regulator
GYMC61_RS16770	COG1879	ABC-type sugar transport system periplasmic component
GYMC61_RS16775	COG1172	Belongs to the binding-protein-dependent transport system permease family
GYMC61_RS16780	COG1129	ABC transporter
GYMC61_RS16785	COG1869	D-ribose catabolic process
GYMC61_RS16790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GYMC61_RS16795	COG1609	Transcriptional regulator
GYMC61_RS16810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GYMC61_RS16835	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GYMC61_RS16840	COG0860	N-Acetylmuramoyl-L-alanine amidase
GYMC61_RS16855	COG0653	protein targeting
GYMC61_RS16865	COG1405	negative regulation of cell septum assembly
GYMC61_RS16865	COG3012	SEC-C Motif Domain Protein
GYMC61_RS16870	COG1405	negative regulation of cell septum assembly
GYMC61_RS16870	COG3012	SEC-C Motif Domain Protein
GYMC61_RS16880	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GYMC61_RS16890	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GYMC61_RS16890	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GYMC61_RS16895	COG3189	MarR family transcriptional regulator
GYMC61_RS16910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GYMC61_RS16915	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GYMC61_RS16925	COG0395	ABC-type sugar transport system, permease component
GYMC61_RS16930	COG1175	transmembrane transport
GYMC61_RS16935	COG1653	transport
GYMC61_RS16950	COG0697	spore germination
GYMC61_RS16965	COG1376	ErfK ybiS ycfS ynhG family protein
GYMC61_RS16990	COG1349	DNA-binding transcription factor activity
GYMC61_RS16995	COG3395	kinase activity
GYMC61_RS17005	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GYMC61_RS17025	COG4464	protein tyrosine phosphatase activity
GYMC61_RS17030	COG1316	TRANSCRIPTIONal
GYMC61_RS17045	COG3944	biosynthesis protein
GYMC61_RS17055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GYMC61_RS17065	COG4786	Flagellar basal body rod
GYMC61_RS17070	COG4786	Flagellar basal body rod
GYMC61_RS17075	COG1077	Cell shape determining protein MreB Mrl
GYMC61_RS17080	COG1609	Transcriptional regulator
GYMC61_RS17100	COG0739	heme binding
GYMC61_RS17105	COG2385	sporulation resulting in formation of a cellular spore
GYMC61_RS17110	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GYMC61_RS17120	COG4836	Membrane
GYMC61_RS17130	COG1007	ATP synthesis coupled electron transport
GYMC61_RS17140	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GYMC61_RS17145	COG0713	ATP synthesis coupled electron transport
GYMC61_RS17150	COG0839	Belongs to the complex I subunit 6 family
GYMC61_RS17155	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GYMC61_RS17160	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GYMC61_RS17165	COG0649	NAD binding
GYMC61_RS17170	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GYMC61_RS17175	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GYMC61_RS17180	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GYMC61_RS17185	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GYMC61_RS17190	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GYMC61_RS17195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GYMC61_RS17200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GYMC61_RS17205	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GYMC61_RS17210	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GYMC61_RS17220	COG0356	it plays a direct role in the translocation of protons across the membrane
GYMC61_RS17235	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GYMC61_RS17240	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GYMC61_RS17245	COG4475	Protein of unknown function (DUF436)
GYMC61_RS17250	COG0698	ribose 5-phosphate isomerase
GYMC61_RS17255	COG0840	transmembrane signaling receptor activity
GYMC61_RS17265	COG1971	Probably functions as a manganese efflux pump
GYMC61_RS17270	COG0009	L-threonylcarbamoyladenylate synthase
GYMC61_RS17285	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GYMC61_RS17295	COG1435	thymidine kinase activity
GYMC61_RS17300	COG0254	rRNA binding
GYMC61_RS17305	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GYMC61_RS17310	COG1494	fructose-1,6-bisphosphatase
GYMC61_RS17315	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GYMC61_RS17320	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GYMC61_RS17330	COG2204	response regulator
GYMC61_RS17335	COG4821	SIS domain
GYMC61_RS17340	COG0504	CTP synthase activity
GYMC61_RS17345	COG3343	RNA polymerase activity
GYMC61_RS17350	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GYMC61_RS17350	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GYMC61_RS17350	COG1703	isobutyryl-CoA mutase activity
GYMC61_RS17360	COG1960	acyl-CoA dehydrogenase activity
GYMC61_RS17365	COG1960	acyl-CoA dehydrogenase activity
GYMC61_RS17370	COG1250	3-hydroxyacyl-CoA dehydrogenase
GYMC61_RS17375	COG0183	Belongs to the thiolase family
GYMC61_RS17380	COG0247	lactate metabolic process
GYMC61_RS17380	COG2181	nitrate reductase activity
GYMC61_RS17385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GYMC61_RS17395	COG0018	arginyl-trna synthetase
GYMC61_RS17410	COG0010	Belongs to the arginase family
GYMC61_RS17415	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GYMC61_RS17420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GYMC61_RS17430	COG1994	Peptidase M50
GYMC61_RS17435	COG1942	4-Oxalocrotonate Tautomerase
GYMC61_RS17440	COG2252	PERMEase
GYMC61_RS17445	COG3465	dGTPase activity
GYMC61_RS17450	COG1078	dGTPase activity
GYMC61_RS17455	COG4844	belongs to the
GYMC61_RS17465	COG0095	Lipoate-protein ligase
GYMC61_RS17470	COG0280	phosphate acetyltransferase
GYMC61_RS17485	COG3773	Cell wall hydrolase
GYMC61_RS17495	COG2363	Small membrane protein
GYMC61_RS17500	COG3711	transcriptional antiterminator
GYMC61_RS17505	COG2723	6-phospho-beta-galactosidase activity
GYMC61_RS17510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GYMC61_RS17510	COG1263	PTS System
GYMC61_RS17510	COG2190	(PTS) system
GYMC61_RS17520	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GYMC61_RS17530	COG1366	Belongs to the anti-sigma-factor antagonist family
GYMC61_RS17535	COG2172	sigma factor antagonist activity
GYMC61_RS17540	COG1191	sigma factor activity
GYMC61_RS17545	COG2208	phosphoserine phosphatase activity
GYMC61_RS17555	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GYMC61_RS17560	COG0423	glycine-tRNA ligase activity
GYMC61_RS17565	COG1216	Glycosyl transferase, family 2
GYMC61_RS17570	COG0477	Major facilitator Superfamily
GYMC61_RS17605	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GYMC61_RS17610	COG0573	inorganic phosphate transmembrane transporter activity
GYMC61_RS17615	COG0581	inorganic phosphate transmembrane transporter activity
GYMC61_RS17620	COG1621	beta-fructofuranosidase activity
GYMC61_RS17625	COG1263	PTS System
GYMC61_RS17625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GYMC61_RS17630	COG3711	transcriptional antiterminator
GYMC61_RS17635	COG2190	(PTS) system
GYMC61_RS17640	COG0473	3-isopropylmalate dehydrogenase activity
GYMC61_RS17645	COG2508	Transcriptional regulator
GYMC61_RS17645	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GYMC61_RS17650	COG0686	Belongs to the AlaDH PNT family
GYMC61_RS17655	COG4636	protein conserved in cyanobacteria
GYMC61_RS17660	COG0351	phosphomethylpyrimidine kinase
GYMC61_RS17665	COG3153	acetyltransferase
GYMC61_RS17665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GYMC61_RS17670	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GYMC61_RS17680	COG0765	amino acid transport
GYMC61_RS17690	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GYMC61_RS17700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GYMC61_RS17710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GYMC61_RS17715	COG1113	amino acid transport
GYMC61_RS17730	COG0723	plastoquinol--plastocyanin reductase activity
GYMC61_RS17730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GYMC61_RS17735	COG1482	cell wall glycoprotein biosynthetic process
GYMC61_RS17740	COG1929	Belongs to the glycerate kinase type-1 family
GYMC61_RS17750	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GYMC61_RS17755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GYMC61_RS17760	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GYMC61_RS17765	COG4853	Protein conserved in bacteria
GYMC61_RS17770	COG4863	YycH protein
GYMC61_RS17775	COG5002	protein histidine kinase activity
GYMC61_RS17780	COG0745	RESPONSE REGULATOR receiver
GYMC61_RS17785	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GYMC61_RS17790	COG0305	Participates in initiation and elongation during chromosome replication
GYMC61_RS17795	COG0359	binds to the 23S rRNA
GYMC61_RS17800	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GYMC61_RS17805	COG4241	membrane
GYMC61_RS17810	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GYMC61_RS17815	COG0629	single-stranded DNA binding
GYMC61_RS17820	COG0360	Binds together with S18 to 16S ribosomal RNA
GYMC61_RS17825	COG0012	GTP binding
GYMC61_RS17830	COG0243	molybdopterin cofactor binding
GYMC61_RS17835	COG4481	Protein conserved in bacteria
GYMC61_RS17840	COG0668	transmembrane transport
GYMC61_RS17850	COG1475	DNA binding
GYMC61_RS17855	COG1192	Involved in chromosome partitioning
GYMC61_RS17860	COG1475	DNA binding
GYMC61_RS17865	COG0357	Ribosomal RNA small subunit methyltransferase G
GYMC61_RS17870	COG0445	tRNA wobble uridine modification
GYMC61_RS17875	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GYMC61_RS17885	COG1847	R3H domain protein
GYMC61_RS17890	COG0706	membrane insertase activity
GYMC61_RS17895	COG0594	ribonuclease P activity
GYMC61_RS17900	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GYMC61_RS17915	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GYMC61_RS17990	COG0516	GMP reductase activity
GYMC61_RS17990	COG0517	IMP dehydrogenase activity
GYMC61_RS18100	COG3209	COG3209 Rhs family protein
GYMC61_RS18120	COG1982	Orn Lys Arg decarboxylase major