GTHT12_RS10790 2b9ab687d6d4ce34399dabc90368d89a 322 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 19 314 6.7E-137 T 06-07-2017 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.14+1.14.13.149|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176 GTHT12_RS10790 2b9ab687d6d4ce34399dabc90368d89a 322 Pfam PF05138 Phenylacetic acid catabolic protein 29 310 4.2E-83 T 06-07-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 GTHT12_RS10790 2b9ab687d6d4ce34399dabc90368d89a 322 Gene3D G3DSA:1.20.1260.10 29 291 8.3E-78 T 06-07-2017 IPR012347 Ferritin-related GTHT12_RS10790 2b9ab687d6d4ce34399dabc90368d89a 322 SUPERFAMILY SSF47240 39 289 7.46E-67 T 06-07-2017 IPR009078 Ferritin-like superfamily GTHT12_RS18040 d7d48dacb7d58ea6576371d3bcc85f35 254 PIRSF PIRSF003073 1 250 4.4E-89 T 06-07-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein GTHT12_RS18040 d7d48dacb7d58ea6576371d3bcc85f35 254 Pfam PF01695 IstB-like ATP binding protein 58 231 8.3E-56 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 GTHT12_RS18040 d7d48dacb7d58ea6576371d3bcc85f35 254 SUPERFAMILY SSF52540 67 244 8.65E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18040 d7d48dacb7d58ea6576371d3bcc85f35 254 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 190 204 6.1E-5 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS18040 d7d48dacb7d58ea6576371d3bcc85f35 254 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 103 121 6.1E-5 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS18040 d7d48dacb7d58ea6576371d3bcc85f35 254 Gene3D G3DSA:3.40.50.300 54 232 7.3E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18040 d7d48dacb7d58ea6576371d3bcc85f35 254 SMART SM00382 99 232 6.4E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS05250 d7d48dacb7d58ea6576371d3bcc85f35 254 PIRSF PIRSF003073 1 250 4.4E-89 T 06-07-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein GTHT12_RS05250 d7d48dacb7d58ea6576371d3bcc85f35 254 Pfam PF01695 IstB-like ATP binding protein 58 231 8.3E-56 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 GTHT12_RS05250 d7d48dacb7d58ea6576371d3bcc85f35 254 SUPERFAMILY SSF52540 67 244 8.65E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05250 d7d48dacb7d58ea6576371d3bcc85f35 254 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 190 204 6.1E-5 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS05250 d7d48dacb7d58ea6576371d3bcc85f35 254 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 103 121 6.1E-5 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS05250 d7d48dacb7d58ea6576371d3bcc85f35 254 Gene3D G3DSA:3.40.50.300 54 232 7.3E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05250 d7d48dacb7d58ea6576371d3bcc85f35 254 SMART SM00382 99 232 6.4E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS18510 d7d48dacb7d58ea6576371d3bcc85f35 254 PIRSF PIRSF003073 1 250 4.4E-89 T 06-07-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein GTHT12_RS18510 d7d48dacb7d58ea6576371d3bcc85f35 254 Pfam PF01695 IstB-like ATP binding protein 58 231 8.3E-56 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 GTHT12_RS18510 d7d48dacb7d58ea6576371d3bcc85f35 254 SUPERFAMILY SSF52540 67 244 8.65E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18510 d7d48dacb7d58ea6576371d3bcc85f35 254 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 190 204 6.1E-5 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS18510 d7d48dacb7d58ea6576371d3bcc85f35 254 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 103 121 6.1E-5 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS18510 d7d48dacb7d58ea6576371d3bcc85f35 254 Gene3D G3DSA:3.40.50.300 54 232 7.3E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18510 d7d48dacb7d58ea6576371d3bcc85f35 254 SMART SM00382 99 232 6.4E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS17315 2b6e0f18cb877ceebf44557944886d19 247 Pfam PF02706 Chain length determinant protein 3 139 6.7E-33 T 06-07-2017 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 GTHT12_RS17315 2b6e0f18cb877ceebf44557944886d19 247 Pfam PF13807 G-rich domain on putative tyrosine kinase 143 194 1.8E-9 T 06-07-2017 IPR032807 Tyrosine kinase, G-rich domain GTHT12_RS13190 35750d5a7f56401ad0d10085a5e710ce 203 Gene3D G3DSA:1.10.150.320 129 201 7.8E-26 T 06-07-2017 GTHT12_RS13190 35750d5a7f56401ad0d10085a5e710ce 203 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 137 200 2.2E-25 T 06-07-2017 IPR004509 Competence protein ComEA, helix-hairpin-helix domain GTHT12_RS13190 35750d5a7f56401ad0d10085a5e710ce 203 SUPERFAMILY SSF47781 127 199 1.11E-30 T 06-07-2017 IPR010994 RuvA domain 2-like GTHT12_RS13190 35750d5a7f56401ad0d10085a5e710ce 203 Pfam PF12836 Helix-hairpin-helix motif 141 200 2.4E-26 T 06-07-2017 GTHT12_RS13190 35750d5a7f56401ad0d10085a5e710ce 203 SMART SM00278 150 169 1.8E-4 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 GTHT12_RS13190 35750d5a7f56401ad0d10085a5e710ce 203 SMART SM00278 180 199 0.89 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 GTHT12_RS13190 35750d5a7f56401ad0d10085a5e710ce 203 Gene3D G3DSA:3.10.560.10 62 104 4.0E-9 T 06-07-2017 GTHT12_RS13190 35750d5a7f56401ad0d10085a5e710ce 203 Pfam PF10531 SLBB domain 61 116 1.3E-15 T 06-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS07410 6327b6f5f32ce38dcbd3be3c923b1261 302 Gene3D G3DSA:3.40.190.10 176 260 7.2E-30 T 06-07-2017 GTHT12_RS07410 6327b6f5f32ce38dcbd3be3c923b1261 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 6.9E-22 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GTHT12_RS07410 6327b6f5f32ce38dcbd3be3c923b1261 302 Gene3D G3DSA:3.40.190.10 89 175 4.0E-23 T 06-07-2017 GTHT12_RS07410 6327b6f5f32ce38dcbd3be3c923b1261 302 SUPERFAMILY SSF53850 88 296 9.42E-43 T 06-07-2017 GTHT12_RS07410 6327b6f5f32ce38dcbd3be3c923b1261 302 Gene3D G3DSA:1.10.10.10 1 84 3.8E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS07410 6327b6f5f32ce38dcbd3be3c923b1261 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.7E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GTHT12_RS07410 6327b6f5f32ce38dcbd3be3c923b1261 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.7E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GTHT12_RS07410 6327b6f5f32ce38dcbd3be3c923b1261 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.7E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GTHT12_RS07410 6327b6f5f32ce38dcbd3be3c923b1261 302 SUPERFAMILY SSF46785 1 84 7.71E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS07410 6327b6f5f32ce38dcbd3be3c923b1261 302 Pfam PF03466 LysR substrate binding domain 88 291 3.9E-47 T 06-07-2017 IPR005119 LysR, substrate-binding GTHT12_RS13015 820f6fc6646530645d500c536f9df024 599 Pfam PF13155 Toprim-like 266 350 1.6E-21 T 06-07-2017 GTHT12_RS13015 820f6fc6646530645d500c536f9df024 599 Pfam PF08275 DNA primase catalytic core, N-terminal domain 129 255 9.7E-42 T 06-07-2017 IPR013264 DNA primase, catalytic core, N-terminal GTHT12_RS13015 820f6fc6646530645d500c536f9df024 599 Pfam PF01807 CHC2 zinc finger 6 99 2.5E-40 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 GTHT12_RS13015 820f6fc6646530645d500c536f9df024 599 SUPERFAMILY SSF56731 118 424 1.12E-103 T 06-07-2017 GTHT12_RS13015 820f6fc6646530645d500c536f9df024 599 SMART SM00493 262 333 3.6E-19 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS13015 820f6fc6646530645d500c536f9df024 599 SUPERFAMILY SSF48024 457 556 8.11E-7 T 06-07-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 GTHT12_RS13015 820f6fc6646530645d500c536f9df024 599 SMART SM00400 36 90 1.7E-36 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 GTHT12_RS13015 820f6fc6646530645d500c536f9df024 599 Gene3D G3DSA:3.90.580.10 4 99 9.6E-44 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 GTHT12_RS13015 820f6fc6646530645d500c536f9df024 599 Pfam PF10410 DnaB-helicase binding domain of primase 370 422 3.5E-13 T 06-07-2017 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 GTHT12_RS13015 820f6fc6646530645d500c536f9df024 599 SUPERFAMILY SSF57783 4 100 5.78E-40 T 06-07-2017 GTHT12_RS13015 820f6fc6646530645d500c536f9df024 599 Hamap MF_00974 DNA primase [dnaG]. 4 587 30.214 T 06-07-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 GTHT12_RS13015 820f6fc6646530645d500c536f9df024 599 PIRSF PIRSF002811 2 597 4.3E-186 T 06-07-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 GTHT12_RS13015 820f6fc6646530645d500c536f9df024 599 Gene3D G3DSA:3.40.1360.10 244 366 6.1E-40 T 06-07-2017 GTHT12_RS13015 820f6fc6646530645d500c536f9df024 599 Gene3D G3DSA:3.90.980.10 118 242 4.8E-43 T 06-07-2017 IPR013264 DNA primase, catalytic core, N-terminal GTHT12_RS13015 820f6fc6646530645d500c536f9df024 599 TIGRFAM TIGR01391 dnaG: DNA primase 4 419 1.3E-155 T 06-07-2017 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 GTHT12_RS14925 525f7ecc61ca4db4712d70c1771ebe33 485 Hamap MF_00484 Glycogen synthase [glgA]. 1 474 48.618 T 06-07-2017 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 GTHT12_RS14925 525f7ecc61ca4db4712d70c1771ebe33 485 SUPERFAMILY SSF53756 2 476 6.63E-136 T 06-07-2017 GTHT12_RS14925 525f7ecc61ca4db4712d70c1771ebe33 485 Pfam PF00534 Glycosyl transferases group 1 286 439 3.6E-14 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 GTHT12_RS14925 525f7ecc61ca4db4712d70c1771ebe33 485 Pfam PF08323 Starch synthase catalytic domain 2 236 2.2E-87 T 06-07-2017 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 GTHT12_RS14925 525f7ecc61ca4db4712d70c1771ebe33 485 Gene3D G3DSA:3.40.50.2000 251 455 2.9E-76 T 06-07-2017 GTHT12_RS14925 525f7ecc61ca4db4712d70c1771ebe33 485 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 1 474 2.5E-180 T 06-07-2017 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 GTHT12_RS03420 af4ad2eaf9e39440b371017eab38008e 342 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 326 4.5E-44 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 GTHT12_RS08945 1a7027b4845cda290a9c2fe48c709456 679 Pfam PF01568 Molydopterin dinucleotide binding domain 565 669 3.2E-19 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 GTHT12_RS08945 1a7027b4845cda290a9c2fe48c709456 679 Pfam PF00384 Molybdopterin oxidoreductase 67 474 8.8E-67 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS08945 1a7027b4845cda290a9c2fe48c709456 679 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 11 63 3.8E-17 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS08945 1a7027b4845cda290a9c2fe48c709456 679 SUPERFAMILY SSF50692 527 679 4.75E-31 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain GTHT12_RS08945 1a7027b4845cda290a9c2fe48c709456 679 SMART SM00926 9 64 4.1E-19 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS08945 1a7027b4845cda290a9c2fe48c709456 679 SUPERFAMILY SSF53706 12 559 1.44E-172 T 06-07-2017 GTHT12_RS08945 1a7027b4845cda290a9c2fe48c709456 679 Gene3D G3DSA:2.40.40.20 545 679 1.3E-32 T 06-07-2017 GTHT12_RS08945 1a7027b4845cda290a9c2fe48c709456 679 Gene3D G3DSA:3.40.228.10 145 322 1.4E-60 T 06-07-2017 GTHT12_RS08945 1a7027b4845cda290a9c2fe48c709456 679 Gene3D G3DSA:2.20.25.90 8 68 3.5E-20 T 06-07-2017 GTHT12_RS08945 1a7027b4845cda290a9c2fe48c709456 679 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 418 435 - T 06-07-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 GTHT12_RS08945 1a7027b4845cda290a9c2fe48c709456 679 Gene3D G3DSA:3.40.50.740 69 144 9.6E-60 T 06-07-2017 GTHT12_RS08945 1a7027b4845cda290a9c2fe48c709456 679 Gene3D G3DSA:3.40.50.740 323 513 9.6E-60 T 06-07-2017 GTHT12_RS11195 962d7c6378d49b217a01f5b444969ecb 121 Gene3D G3DSA:3.10.180.10 8 119 2.4E-39 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GTHT12_RS11195 962d7c6378d49b217a01f5b444969ecb 121 SUPERFAMILY SSF54593 4 120 1.61E-22 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GTHT12_RS11195 962d7c6378d49b217a01f5b444969ecb 121 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 117 2.2E-7 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain GTHT12_RS11030 d4d9ea1cbd9ce2342bdd9e121372787e 300 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 22 70 1.4E-11 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain GTHT12_RS11030 d4d9ea1cbd9ce2342bdd9e121372787e 300 SUPERFAMILY SSF161098 88 274 2.22E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS11030 d4d9ea1cbd9ce2342bdd9e121372787e 300 Gene3D G3DSA:1.10.3720.10 86 290 2.8E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS11030 d4d9ea1cbd9ce2342bdd9e121372787e 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 293 3.6E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS04745 fb40eaefd44c6bdbb936f1047399e933 145 Pfam PF00248 Aldo/keto reductase family 32 145 1.2E-22 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain GTHT12_RS04745 fb40eaefd44c6bdbb936f1047399e933 145 Gene3D G3DSA:3.20.20.100 8 145 3.0E-51 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain GTHT12_RS04745 fb40eaefd44c6bdbb936f1047399e933 145 SUPERFAMILY SSF51430 9 145 4.32E-47 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain GTHT12_RS04745 fb40eaefd44c6bdbb936f1047399e933 145 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 45 62 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 GTHT12_RS04745 fb40eaefd44c6bdbb936f1047399e933 145 PRINTS PR00069 Aldo-keto reductase signature 101 119 6.6E-23 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GTHT12_RS04745 fb40eaefd44c6bdbb936f1047399e933 145 PRINTS PR00069 Aldo-keto reductase signature 41 65 6.6E-23 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GTHT12_RS04745 fb40eaefd44c6bdbb936f1047399e933 145 PRINTS PR00069 Aldo-keto reductase signature 131 145 6.6E-23 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GTHT12_RS17680 00b2f54396db1da34abf0875a059ca83 557 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 134 143 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS17680 00b2f54396db1da34abf0875a059ca83 557 PRINTS PR01038 Arginyl-tRNA synthetase signature 124 139 1.0E-24 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 GTHT12_RS17680 00b2f54396db1da34abf0875a059ca83 557 PRINTS PR01038 Arginyl-tRNA synthetase signature 306 327 1.0E-24 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 GTHT12_RS17680 00b2f54396db1da34abf0875a059ca83 557 PRINTS PR01038 Arginyl-tRNA synthetase signature 139 155 1.0E-24 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 GTHT12_RS17680 00b2f54396db1da34abf0875a059ca83 557 PRINTS PR01038 Arginyl-tRNA synthetase signature 163 176 1.0E-24 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 GTHT12_RS17680 00b2f54396db1da34abf0875a059ca83 557 SUPERFAMILY SSF52374 117 448 1.18E-101 T 06-07-2017 GTHT12_RS17680 00b2f54396db1da34abf0875a059ca83 557 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 10 94 5.5E-26 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 GTHT12_RS17680 00b2f54396db1da34abf0875a059ca83 557 Gene3D G3DSA:1.10.730.10 443 557 1.2E-42 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS17680 00b2f54396db1da34abf0875a059ca83 557 Hamap MF_00123 Arginine--tRNA ligase [argS]. 9 557 28.342 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 GTHT12_RS17680 00b2f54396db1da34abf0875a059ca83 557 Pfam PF05746 DALR anticodon binding domain 437 557 5.4E-38 T 06-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 GTHT12_RS17680 00b2f54396db1da34abf0875a059ca83 557 SMART SM01016 9 95 2.9E-37 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 GTHT12_RS17680 00b2f54396db1da34abf0875a059ca83 557 Gene3D G3DSA:3.40.50.620 117 442 7.7E-110 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS17680 00b2f54396db1da34abf0875a059ca83 557 SMART SM00836 437 557 4.7E-50 T 06-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 GTHT12_RS17680 00b2f54396db1da34abf0875a059ca83 557 Gene3D G3DSA:3.30.1360.70 6 114 2.0E-32 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 GTHT12_RS17680 00b2f54396db1da34abf0875a059ca83 557 Pfam PF00750 tRNA synthetases class I (R) 104 400 3.3E-28 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 GTHT12_RS17680 00b2f54396db1da34abf0875a059ca83 557 SUPERFAMILY SSF47323 431 557 3.47E-35 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS17680 00b2f54396db1da34abf0875a059ca83 557 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 7 557 1.0E-170 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 GTHT12_RS17680 00b2f54396db1da34abf0875a059ca83 557 SUPERFAMILY SSF55190 6 115 1.57E-26 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 GTHT12_RS06765 cebf6ce95a34ae3151f45020bcf43547 909 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 4 819 0.0 T 06-07-2017 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 GTHT12_RS06765 cebf6ce95a34ae3151f45020bcf43547 909 SMART SM00533 273 582 2.4E-110 T 06-07-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 GTHT12_RS06765 cebf6ce95a34ae3151f45020bcf43547 909 SUPERFAMILY SSF48334 256 555 3.27E-91 T 06-07-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 GTHT12_RS06765 cebf6ce95a34ae3151f45020bcf43547 909 Gene3D G3DSA:3.40.50.300 558 790 5.8E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06765 cebf6ce95a34ae3151f45020bcf43547 909 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 4 900 25.728 T 06-07-2017 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 GTHT12_RS06765 cebf6ce95a34ae3151f45020bcf43547 909 Pfam PF00488 MutS domain V 603 789 1.8E-82 T 06-07-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 GTHT12_RS06765 cebf6ce95a34ae3151f45020bcf43547 909 Gene3D G3DSA:1.10.1420.10 252 458 7.3E-58 T 06-07-2017 GTHT12_RS06765 cebf6ce95a34ae3151f45020bcf43547 909 SUPERFAMILY SSF55271 2 112 8.11E-44 T 06-07-2017 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 GTHT12_RS06765 cebf6ce95a34ae3151f45020bcf43547 909 SMART SM00534 599 786 2.1E-116 T 06-07-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 GTHT12_RS06765 cebf6ce95a34ae3151f45020bcf43547 909 Pfam PF01624 MutS domain I 5 115 1.8E-46 T 06-07-2017 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 GTHT12_RS06765 cebf6ce95a34ae3151f45020bcf43547 909 SUPERFAMILY SSF53150 114 268 2.62E-29 T 06-07-2017 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 GTHT12_RS06765 cebf6ce95a34ae3151f45020bcf43547 909 Pfam PF05188 MutS domain II 135 241 2.8E-8 T 06-07-2017 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 GTHT12_RS06765 cebf6ce95a34ae3151f45020bcf43547 909 Pfam PF05190 MutS family domain IV 418 509 2.3E-30 T 06-07-2017 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 GTHT12_RS06765 cebf6ce95a34ae3151f45020bcf43547 909 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 680 696 - T 06-07-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 GTHT12_RS06765 cebf6ce95a34ae3151f45020bcf43547 909 Gene3D G3DSA:3.40.1170.10 2 116 2.5E-52 T 06-07-2017 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 GTHT12_RS06765 cebf6ce95a34ae3151f45020bcf43547 909 SUPERFAMILY SSF52540 558 790 4.26E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06765 cebf6ce95a34ae3151f45020bcf43547 909 Gene3D G3DSA:3.30.420.110 124 248 6.5E-20 T 06-07-2017 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 GTHT12_RS06765 cebf6ce95a34ae3151f45020bcf43547 909 Pfam PF05192 MutS domain III 262 550 8.3E-46 T 06-07-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 GTHT12_RS17185 78b7ca2b941a65e21663f15e3944ec3c 555 Gene3D G3DSA:1.25.10.10 266 426 1.9E-14 T 06-07-2017 IPR011989 Armadillo-like helical GTHT12_RS17185 78b7ca2b941a65e21663f15e3944ec3c 555 Pfam PF13646 HEAT repeats 358 430 1.3E-6 T 06-07-2017 GTHT12_RS17185 78b7ca2b941a65e21663f15e3944ec3c 555 SUPERFAMILY SSF48371 195 455 1.11E-10 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 GTHT12_RS18935 33789e22bffceb0e28fc3c2b65a07e74 706 SMART SM00437 273 553 1.1E-70 T 06-07-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 GTHT12_RS18935 33789e22bffceb0e28fc3c2b65a07e74 706 SMART SM00436 129 224 6.3E-38 T 06-07-2017 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 GTHT12_RS18935 33789e22bffceb0e28fc3c2b65a07e74 706 Pfam PF01131 DNA topoisomerase 156 588 1.6E-107 T 06-07-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 GTHT12_RS18935 33789e22bffceb0e28fc3c2b65a07e74 706 Pfam PF01751 Toprim domain 3 136 2.7E-17 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS18935 33789e22bffceb0e28fc3c2b65a07e74 706 Gene3D G3DSA:2.70.20.10 219 252 1.6E-33 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 GTHT12_RS18935 33789e22bffceb0e28fc3c2b65a07e74 706 Gene3D G3DSA:2.70.20.10 359 476 1.6E-33 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 GTHT12_RS18935 33789e22bffceb0e28fc3c2b65a07e74 706 Gene3D G3DSA:1.10.460.10 477 602 1.3E-50 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 GTHT12_RS18935 33789e22bffceb0e28fc3c2b65a07e74 706 Gene3D G3DSA:1.10.460.10 159 218 1.3E-50 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 GTHT12_RS18935 33789e22bffceb0e28fc3c2b65a07e74 706 SMART SM00493 1 128 2.7E-20 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS18935 33789e22bffceb0e28fc3c2b65a07e74 706 Pfam PF13342 C-terminal repeat of topoisomerase 650 705 7.6E-17 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat GTHT12_RS18935 33789e22bffceb0e28fc3c2b65a07e74 706 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 310 324 - T 06-07-2017 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 GTHT12_RS18935 33789e22bffceb0e28fc3c2b65a07e74 706 TIGRFAM TIGR01056 topB: DNA topoisomerase III 2 689 8.0E-193 T 06-07-2017 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 GTHT12_RS18935 33789e22bffceb0e28fc3c2b65a07e74 706 SUPERFAMILY SSF56712 1 602 8.5E-168 T 06-07-2017 IPR023405 DNA topoisomerase, type IA, core domain GTHT12_RS18935 33789e22bffceb0e28fc3c2b65a07e74 706 Gene3D G3DSA:3.40.50.140 1 155 7.5E-46 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS18935 33789e22bffceb0e28fc3c2b65a07e74 706 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 194 212 5.6E-23 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS18935 33789e22bffceb0e28fc3c2b65a07e74 706 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 102 115 5.6E-23 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS18935 33789e22bffceb0e28fc3c2b65a07e74 706 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 315 324 5.6E-23 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS18935 33789e22bffceb0e28fc3c2b65a07e74 706 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 396 412 5.6E-23 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS18935 33789e22bffceb0e28fc3c2b65a07e74 706 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 516 530 5.6E-23 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS10305 d2cde89706bfc89ec324f6254632405e 445 PIRSF PIRSF000521 12 432 1.3E-46 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GTHT12_RS10305 d2cde89706bfc89ec324f6254632405e 445 Gene3D G3DSA:3.90.1150.10 312 431 1.0E-46 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS10305 d2cde89706bfc89ec324f6254632405e 445 Gene3D G3DSA:3.40.640.10 63 311 7.0E-84 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS10305 d2cde89706bfc89ec324f6254632405e 445 SUPERFAMILY SSF53383 21 431 5.54E-133 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS10305 d2cde89706bfc89ec324f6254632405e 445 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 245 282 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GTHT12_RS10305 d2cde89706bfc89ec324f6254632405e 445 Pfam PF00202 Aminotransferase class-III 24 429 5.2E-134 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GTHT12_RS02785 81e2ba822a1f5d8ef57c9c17aed214ba 208 Pfam PF04012 PspA/IM30 family 3 198 7.2E-17 T 06-07-2017 IPR007157 PspA/IM30 GTHT12_RS13375 d0724a37d191ea3932355e19d64fbe0a 88 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 83 2.0E-37 T 06-07-2017 IPR009309 Uncharacterised protein family UPF0297 GTHT12_RS13375 d0724a37d191ea3932355e19d64fbe0a 88 Hamap MF_01507 UPF0297 protein . 1 85 28.115 T 06-07-2017 IPR009309 Uncharacterised protein family UPF0297 GTHT12_RS13375 d0724a37d191ea3932355e19d64fbe0a 88 PIRSF PIRSF037258 1 88 1.3E-44 T 06-07-2017 IPR009309 Uncharacterised protein family UPF0297 GTHT12_RS15855 bd1da281f94b37c5d79bd611f88b894e 755 SUPERFAMILY SSF50249 54 134 1.59E-19 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS15855 bd1da281f94b37c5d79bd611f88b894e 755 TIGRFAM TIGR02063 RNase_R: ribonuclease R 5 707 5.9E-292 T 06-07-2017 IPR011805 Ribonuclease R GO:0003723|GO:0004518 GTHT12_RS15855 bd1da281f94b37c5d79bd611f88b894e 755 Gene3D G3DSA:2.40.50.140 627 707 7.3E-23 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS15855 bd1da281f94b37c5d79bd611f88b894e 755 Pfam PF08206 Ribonuclease B OB domain 73 131 1.3E-23 T 06-07-2017 IPR013223 Ribonuclease B, N-terminal OB domain GTHT12_RS15855 bd1da281f94b37c5d79bd611f88b894e 755 Pfam PF08206 Ribonuclease B OB domain 148 200 1.4E-9 T 06-07-2017 IPR013223 Ribonuclease B, N-terminal OB domain GTHT12_RS15855 bd1da281f94b37c5d79bd611f88b894e 755 Gene3D G3DSA:1.10.10.10 8 64 2.5E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS15855 bd1da281f94b37c5d79bd611f88b894e 755 Pfam PF00773 RNB domain 247 575 1.6E-115 T 06-07-2017 GTHT12_RS15855 bd1da281f94b37c5d79bd611f88b894e 755 SMART SM00955 247 577 7.2E-187 T 06-07-2017 GTHT12_RS15855 bd1da281f94b37c5d79bd611f88b894e 755 SUPERFAMILY SSF50249 207 624 1.26E-151 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS15855 bd1da281f94b37c5d79bd611f88b894e 755 SUPERFAMILY SSF50249 625 705 2.09E-23 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS15855 bd1da281f94b37c5d79bd611f88b894e 755 SMART SM00357 72 132 2.1E-16 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 GTHT12_RS15855 bd1da281f94b37c5d79bd611f88b894e 755 SMART SM00357 137 201 1.4E-7 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 GTHT12_RS15855 bd1da281f94b37c5d79bd611f88b894e 755 ProSitePatterns PS01175 Ribonuclease II family signature. 544 568 - T 06-07-2017 IPR022966 Ribonuclease II/R, conserved site GTHT12_RS15855 bd1da281f94b37c5d79bd611f88b894e 755 SUPERFAMILY SSF50249 125 224 2.18E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS15855 bd1da281f94b37c5d79bd611f88b894e 755 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 57 707 1.3E-251 T 06-07-2017 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 GTHT12_RS15855 bd1da281f94b37c5d79bd611f88b894e 755 Pfam PF00575 S1 RNA binding domain 624 705 2.7E-15 T 06-07-2017 IPR003029 S1 domain GO:0003676 GTHT12_RS15855 bd1da281f94b37c5d79bd611f88b894e 755 Hamap MF_01895 Ribonuclease R [rnr]. 24 707 61.99 T 06-07-2017 IPR011805 Ribonuclease R GO:0003723|GO:0004518 GTHT12_RS15855 bd1da281f94b37c5d79bd611f88b894e 755 SMART SM00316 625 707 9.1E-20 T 06-07-2017 IPR022967 RNA-binding domain, S1 GTHT12_RS03960 6f88c357ac3e74123a84fa7a64c19736 616 Pfam PF02219 Methylenetetrahydrofolate reductase 321 573 7.3E-24 T 06-07-2017 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 GTHT12_RS03960 6f88c357ac3e74123a84fa7a64c19736 616 SUPERFAMILY SSF82282 3 361 6.8E-105 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 GTHT12_RS03960 6f88c357ac3e74123a84fa7a64c19736 616 Pfam PF02574 Homocysteine S-methyltransferase 12 280 2.3E-61 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 GTHT12_RS03960 6f88c357ac3e74123a84fa7a64c19736 616 SUPERFAMILY SSF51730 315 602 3.14E-69 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like GTHT12_RS03960 6f88c357ac3e74123a84fa7a64c19736 616 Gene3D G3DSA:3.20.20.330 3 323 1.6E-102 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 GTHT12_RS03960 6f88c357ac3e74123a84fa7a64c19736 616 Gene3D G3DSA:3.20.20.220 324 605 2.7E-61 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like GTHT12_RS04165 608115e9980144a0af7c2a9db21ee129 419 SUPERFAMILY SSF63867 337 413 9.68E-17 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 GTHT12_RS04165 608115e9980144a0af7c2a9db21ee129 419 Gene3D G3DSA:3.40.980.10 172 340 1.9E-57 T 06-07-2017 IPR001453 MoaB/Mog domain GTHT12_RS04165 608115e9980144a0af7c2a9db21ee129 419 Gene3D G3DSA:3.90.105.10 140 171 7.1E-19 T 06-07-2017 GTHT12_RS04165 608115e9980144a0af7c2a9db21ee129 419 Gene3D G3DSA:2.170.190.11 50 139 2.1E-28 T 06-07-2017 GTHT12_RS04165 608115e9980144a0af7c2a9db21ee129 419 Pfam PF00994 Probable molybdopterin binding domain 193 326 4.6E-22 T 06-07-2017 IPR001453 MoaB/Mog domain GTHT12_RS04165 608115e9980144a0af7c2a9db21ee129 419 SUPERFAMILY SSF63882 8 185 2.75E-51 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 GTHT12_RS04165 608115e9980144a0af7c2a9db21ee129 419 SUPERFAMILY SSF53218 186 328 9.55E-39 T 06-07-2017 IPR001453 MoaB/Mog domain GTHT12_RS04165 608115e9980144a0af7c2a9db21ee129 419 Gene3D G3DSA:2.40.340.10 341 412 2.3E-17 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 GTHT12_RS04165 608115e9980144a0af7c2a9db21ee129 419 Pfam PF03454 MoeA C-terminal region (domain IV) 340 411 1.2E-17 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 GTHT12_RS04165 608115e9980144a0af7c2a9db21ee129 419 SMART SM00852 189 327 1.7E-35 T 06-07-2017 IPR001453 MoaB/Mog domain GTHT12_RS04165 608115e9980144a0af7c2a9db21ee129 419 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 176 4.8E-32 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 GTHT12_RS04165 608115e9980144a0af7c2a9db21ee129 419 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 185 323 2.1E-30 T 06-07-2017 IPR001453 MoaB/Mog domain GTHT12_RS13795 1428d94f65f6a45a72233d5e4189325e 429 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 7 426 1.9E-201 T 06-07-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 GTHT12_RS13795 1428d94f65f6a45a72233d5e4189325e 429 Gene3D G3DSA:3.40.640.10 73 318 2.9E-83 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS13795 1428d94f65f6a45a72233d5e4189325e 429 SUPERFAMILY SSF53383 4 426 2.21E-136 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS13795 1428d94f65f6a45a72233d5e4189325e 429 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 6 427 106.635 T 06-07-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 GTHT12_RS13795 1428d94f65f6a45a72233d5e4189325e 429 Pfam PF00202 Aminotransferase class-III 34 393 7.4E-78 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GTHT12_RS13795 1428d94f65f6a45a72233d5e4189325e 429 Gene3D G3DSA:3.90.1150.10 4 72 1.2E-46 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS13795 1428d94f65f6a45a72233d5e4189325e 429 Gene3D G3DSA:3.90.1150.10 321 426 1.2E-46 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS13795 1428d94f65f6a45a72233d5e4189325e 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 273 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GTHT12_RS02185 df2037700456f79d9e9fac36a4dc794f 413 Pfam PF00672 HAMP domain 114 181 1.4E-7 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS02185 df2037700456f79d9e9fac36a4dc794f 413 Gene3D G3DSA:3.30.565.10 247 410 2.1E-39 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS02185 df2037700456f79d9e9fac36a4dc794f 413 SUPERFAMILY SSF55874 249 410 2.62E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS02185 df2037700456f79d9e9fac36a4dc794f 413 Pfam PF00512 His Kinase A (phospho-acceptor) domain 194 258 3.9E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS02185 df2037700456f79d9e9fac36a4dc794f 413 PRINTS PR00344 Bacterial sensor protein C-terminal signature 359 369 3.7E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS02185 df2037700456f79d9e9fac36a4dc794f 413 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 392 3.7E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS02185 df2037700456f79d9e9fac36a4dc794f 413 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 411 3.7E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS02185 df2037700456f79d9e9fac36a4dc794f 413 PRINTS PR00344 Bacterial sensor protein C-terminal signature 341 355 3.7E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS02185 df2037700456f79d9e9fac36a4dc794f 413 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 305 410 5.5E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS02185 df2037700456f79d9e9fac36a4dc794f 413 Gene3D G3DSA:1.10.287.130 185 246 7.3E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS02185 df2037700456f79d9e9fac36a4dc794f 413 SMART SM00304 133 185 5.1E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS02185 df2037700456f79d9e9fac36a4dc794f 413 SMART SM00388 193 259 6.4E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS02185 df2037700456f79d9e9fac36a4dc794f 413 SUPERFAMILY SSF158472 133 183 3.79E-5 T 06-07-2017 GTHT12_RS02185 df2037700456f79d9e9fac36a4dc794f 413 SMART SM00387 304 413 2.6E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS02185 df2037700456f79d9e9fac36a4dc794f 413 SUPERFAMILY SSF47384 179 259 5.3E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS13770 56b6589a93ee23c41e27eea3f76c2dfa 880 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 814 879 8.0E-25 T 06-07-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 GTHT12_RS13770 56b6589a93ee23c41e27eea3f76c2dfa 880 Hamap MF_02004 Valine--tRNA ligase [valS]. 8 879 16.412 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 GTHT12_RS13770 56b6589a93ee23c41e27eea3f76c2dfa 880 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 21 565 5.6E-225 T 06-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS13770 56b6589a93ee23c41e27eea3f76c2dfa 880 SUPERFAMILY SSF46589 814 878 4.66E-17 T 06-07-2017 IPR010978 tRNA-binding arm GO:0000166 GTHT12_RS13770 56b6589a93ee23c41e27eea3f76c2dfa 880 Pfam PF08264 Anticodon-binding domain of tRNA 608 755 5.7E-45 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 GTHT12_RS13770 56b6589a93ee23c41e27eea3f76c2dfa 880 Gene3D G3DSA:3.90.740.10 200 342 9.8E-53 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 GTHT12_RS13770 56b6589a93ee23c41e27eea3f76c2dfa 880 PRINTS PR00986 Valyl-tRNA synthetase signature 477 495 1.7E-40 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 GTHT12_RS13770 56b6589a93ee23c41e27eea3f76c2dfa 880 PRINTS PR00986 Valyl-tRNA synthetase signature 42 53 1.7E-40 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 GTHT12_RS13770 56b6589a93ee23c41e27eea3f76c2dfa 880 PRINTS PR00986 Valyl-tRNA synthetase signature 351 364 1.7E-40 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 GTHT12_RS13770 56b6589a93ee23c41e27eea3f76c2dfa 880 PRINTS PR00986 Valyl-tRNA synthetase signature 236 253 1.7E-40 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 GTHT12_RS13770 56b6589a93ee23c41e27eea3f76c2dfa 880 PRINTS PR00986 Valyl-tRNA synthetase signature 445 466 1.7E-40 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 GTHT12_RS13770 56b6589a93ee23c41e27eea3f76c2dfa 880 Gene3D G3DSA:3.40.50.620 346 564 9.0E-144 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS13770 56b6589a93ee23c41e27eea3f76c2dfa 880 Gene3D G3DSA:3.40.50.620 11 199 9.0E-144 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS13770 56b6589a93ee23c41e27eea3f76c2dfa 880 TIGRFAM TIGR00422 valS: valine--tRNA ligase 8 860 0.0 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 GTHT12_RS13770 56b6589a93ee23c41e27eea3f76c2dfa 880 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS13770 56b6589a93ee23c41e27eea3f76c2dfa 880 SUPERFAMILY SSF50677 196 347 3.01E-67 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 GTHT12_RS13770 56b6589a93ee23c41e27eea3f76c2dfa 880 Gene3D G3DSA:1.10.730.10 565 745 8.2E-69 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS13770 56b6589a93ee23c41e27eea3f76c2dfa 880 SUPERFAMILY SSF52374 346 575 2.6E-146 T 06-07-2017 GTHT12_RS13770 56b6589a93ee23c41e27eea3f76c2dfa 880 SUPERFAMILY SSF52374 5 198 2.6E-146 T 06-07-2017 GTHT12_RS13770 56b6589a93ee23c41e27eea3f76c2dfa 880 SUPERFAMILY SSF47323 577 829 2.06E-79 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS13770 56b6589a93ee23c41e27eea3f76c2dfa 880 Gene3D G3DSA:1.10.287.380 807 878 2.4E-9 T 06-07-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 GTHT12_RS15390 7e97ef3081063c16795f3e2f8af73dad 497 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 184 489 2.6E-115 T 06-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 GTHT12_RS15390 7e97ef3081063c16795f3e2f8af73dad 497 PRINTS PR00481 Cytosol aminopeptidase signature 260 277 5.9E-52 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 GTHT12_RS15390 7e97ef3081063c16795f3e2f8af73dad 497 PRINTS PR00481 Cytosol aminopeptidase signature 341 361 5.9E-52 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 GTHT12_RS15390 7e97ef3081063c16795f3e2f8af73dad 497 PRINTS PR00481 Cytosol aminopeptidase signature 369 384 5.9E-52 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 GTHT12_RS15390 7e97ef3081063c16795f3e2f8af73dad 497 PRINTS PR00481 Cytosol aminopeptidase signature 319 340 5.9E-52 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 GTHT12_RS15390 7e97ef3081063c16795f3e2f8af73dad 497 PRINTS PR00481 Cytosol aminopeptidase signature 282 303 5.9E-52 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 GTHT12_RS15390 7e97ef3081063c16795f3e2f8af73dad 497 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 345 352 - T 06-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 GTHT12_RS15390 7e97ef3081063c16795f3e2f8af73dad 497 Gene3D G3DSA:3.40.220.10 2 160 6.2E-31 T 06-07-2017 GTHT12_RS15390 7e97ef3081063c16795f3e2f8af73dad 497 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 2 497 35.107 T 06-07-2017 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 GTHT12_RS15390 7e97ef3081063c16795f3e2f8af73dad 497 SUPERFAMILY SSF52949 2 178 2.12E-37 T 06-07-2017 GTHT12_RS15390 7e97ef3081063c16795f3e2f8af73dad 497 SUPERFAMILY SSF53187 180 494 2.2E-115 T 06-07-2017 GTHT12_RS15390 7e97ef3081063c16795f3e2f8af73dad 497 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 19 147 1.9E-27 T 06-07-2017 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 GTHT12_RS15390 7e97ef3081063c16795f3e2f8af73dad 497 Gene3D G3DSA:3.40.630.10 179 495 1.0E-130 T 06-07-2017 GTHT12_RS10425 23114767ec205a4c373db1525b96ae78 571 SUPERFAMILY SSF55785 115 208 1.38E-16 T 06-07-2017 IPR000014 PAS domain GTHT12_RS10425 23114767ec205a4c373db1525b96ae78 571 Gene3D G3DSA:3.10.580.10 12 84 1.1E-5 T 06-07-2017 GTHT12_RS10425 23114767ec205a4c373db1525b96ae78 571 SUPERFAMILY SSF54631 10 134 4.06E-7 T 06-07-2017 GTHT12_RS10425 23114767ec205a4c373db1525b96ae78 571 SMART SM00382 278 426 1.7E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS10425 23114767ec205a4c373db1525b96ae78 571 Pfam PF00989 PAS fold 116 166 1.3E-9 T 06-07-2017 IPR013767 PAS fold GO:0006355 GTHT12_RS10425 23114767ec205a4c373db1525b96ae78 571 Gene3D G3DSA:1.10.8.60 432 505 5.5E-23 T 06-07-2017 GTHT12_RS10425 23114767ec205a4c373db1525b96ae78 571 Gene3D G3DSA:3.40.50.300 256 431 7.2E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10425 23114767ec205a4c373db1525b96ae78 571 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 118 165 5.7E-7 T 06-07-2017 IPR000014 PAS domain GTHT12_RS10425 23114767ec205a4c373db1525b96ae78 571 SUPERFAMILY SSF46689 472 570 5.02E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS10425 23114767ec205a4c373db1525b96ae78 571 Gene3D G3DSA:3.30.450.20 110 167 9.4E-14 T 06-07-2017 GTHT12_RS10425 23114767ec205a4c373db1525b96ae78 571 SMART SM00091 114 180 1.6E-7 T 06-07-2017 IPR000014 PAS domain GTHT12_RS10425 23114767ec205a4c373db1525b96ae78 571 SUPERFAMILY SSF52540 258 503 6.19E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10425 23114767ec205a4c373db1525b96ae78 571 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 535 552 5.1E-12 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GTHT12_RS10425 23114767ec205a4c373db1525b96ae78 571 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 552 571 5.1E-12 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GTHT12_RS10425 23114767ec205a4c373db1525b96ae78 571 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 472 481 - T 06-07-2017 IPR025944 Sigma-54 interaction domain, conserved site GTHT12_RS10425 23114767ec205a4c373db1525b96ae78 571 Pfam PF02954 Bacterial regulatory protein, Fis family 532 569 1.3E-14 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GTHT12_RS10425 23114767ec205a4c373db1525b96ae78 571 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 345 360 - T 06-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 GTHT12_RS10425 23114767ec205a4c373db1525b96ae78 571 Pfam PF00158 Sigma-54 interaction domain 258 426 1.7E-69 T 06-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 GTHT12_RS10425 23114767ec205a4c373db1525b96ae78 571 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 282 295 - T 06-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 GTHT12_RS10425 23114767ec205a4c373db1525b96ae78 571 Gene3D G3DSA:1.10.10.60 520 570 2.0E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 SUPERFAMILY SSF54292 6 128 4.16E-32 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 266 934 3.2E-261 T 06-07-2017 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 SUPERFAMILY SSF54862 131 220 5.44E-19 T 06-07-2017 GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 Gene3D G3DSA:2.20.25.90 265 316 6.6E-22 T 06-07-2017 GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 194 205 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 Gene3D G3DSA:2.40.40.20 795 936 2.6E-37 T 06-07-2017 GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 76 9.9E-16 T 06-07-2017 GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 Gene3D G3DSA:3.10.20.30 3 58 7.1E-4 T 06-07-2017 IPR012675 Beta-grasp domain GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 SUPERFAMILY SSF53706 255 781 4.71E-201 T 06-07-2017 GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 Pfam PF00384 Molybdopterin oxidoreductase 318 742 8.9E-89 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 863 890 - T 06-07-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 Pfam PF01568 Molydopterin dinucleotide binding domain 825 930 6.1E-22 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 Gene3D G3DSA:3.30.70.20 136 199 7.0E-17 T 06-07-2017 GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 261 315 1.9E-17 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 Gene3D G3DSA:1.10.1060.10 200 264 1.8E-5 T 06-07-2017 GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 85 124 1.9E-11 T 06-07-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 SMART SM00926 261 315 9.3E-17 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 PIRSF PIRSF036643 1 968 0.0 T 06-07-2017 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 Pfam PF12838 4Fe-4S dicluster domain 150 208 2.3E-6 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 SUPERFAMILY SSF50692 789 936 7.25E-37 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 SMART SM00929 85 126 6.2E-14 T 06-07-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 Gene3D G3DSA:3.40.228.10 394 578 3.1E-58 T 06-07-2017 GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 Gene3D G3DSA:3.40.50.740 579 794 1.8E-98 T 06-07-2017 GTHT12_RS02940 324a0b392c83c28111b1c9b620f3acfc 987 Gene3D G3DSA:3.40.50.740 318 393 1.8E-98 T 06-07-2017 GTHT12_RS08190 1bb169a75f5d32d89379aae5edb4e806 420 Gene3D G3DSA:3.30.450.20 80 183 3.9E-9 T 06-07-2017 GTHT12_RS08190 1bb169a75f5d32d89379aae5edb4e806 420 Gene3D G3DSA:3.30.565.10 262 412 4.9E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS08190 1bb169a75f5d32d89379aae5edb4e806 420 SUPERFAMILY SSF55785 82 182 3.49E-11 T 06-07-2017 IPR000014 PAS domain GTHT12_RS08190 1bb169a75f5d32d89379aae5edb4e806 420 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 81 194 3.7E-6 T 06-07-2017 IPR000014 PAS domain GTHT12_RS08190 1bb169a75f5d32d89379aae5edb4e806 420 Gene3D G3DSA:1.10.287.130 190 258 4.6E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS08190 1bb169a75f5d32d89379aae5edb4e806 420 SUPERFAMILY SSF55874 252 413 9.95E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS08190 1bb169a75f5d32d89379aae5edb4e806 420 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 307 412 4.2E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS08190 1bb169a75f5d32d89379aae5edb4e806 420 SMART SM00387 307 413 2.2E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS08190 1bb169a75f5d32d89379aae5edb4e806 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 410 4.2E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS08190 1bb169a75f5d32d89379aae5edb4e806 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 392 4.2E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS08190 1bb169a75f5d32d89379aae5edb4e806 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 359 4.2E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS08190 1bb169a75f5d32d89379aae5edb4e806 420 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 373 4.2E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS08190 1bb169a75f5d32d89379aae5edb4e806 420 SMART SM00388 197 262 5.0E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS08190 1bb169a75f5d32d89379aae5edb4e806 420 Pfam PF00512 His Kinase A (phospho-acceptor) domain 199 258 2.0E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS08190 1bb169a75f5d32d89379aae5edb4e806 420 SUPERFAMILY SSF47384 190 259 3.14E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS04405 f867442ccc5889026b83e1079bffa1e2 299 SUPERFAMILY SSF55120 76 296 8.8E-76 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS04405 f867442ccc5889026b83e1079bffa1e2 299 Pfam PF00849 RNA pseudouridylate synthase 91 240 4.8E-32 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS04405 f867442ccc5889026b83e1079bffa1e2 299 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 133 147 - T 06-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS04405 f867442ccc5889026b83e1079bffa1e2 299 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 13 296 4.2E-76 T 06-07-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS12550 22583805af663e28e4dcb226df0df4ce 451 SMART SM00878 337 443 2.6E-73 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GTHT12_RS12550 22583805af663e28e4dcb226df0df4ce 451 Pfam PF02785 Biotin carboxylase C-terminal domain 337 443 1.1E-44 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GTHT12_RS12550 22583805af663e28e4dcb226df0df4ce 451 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GTHT12_RS12550 22583805af663e28e4dcb226df0df4ce 451 SUPERFAMILY SSF52440 1 113 1.65E-50 T 06-07-2017 IPR016185 Pre-ATP-grasp domain GTHT12_RS12550 22583805af663e28e4dcb226df0df4ce 451 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 4.1E-47 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GTHT12_RS12550 22583805af663e28e4dcb226df0df4ce 451 Gene3D G3DSA:3.30.470.20 203 444 1.8E-108 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 GTHT12_RS12550 22583805af663e28e4dcb226df0df4ce 451 SUPERFAMILY SSF51246 332 443 6.28E-48 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GTHT12_RS12550 22583805af663e28e4dcb226df0df4ce 451 Gene3D G3DSA:3.40.50.20 1 128 4.9E-53 T 06-07-2017 IPR016185 Pre-ATP-grasp domain GTHT12_RS12550 22583805af663e28e4dcb226df0df4ce 451 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 448 1.0E-241 T 06-07-2017 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 GTHT12_RS12550 22583805af663e28e4dcb226df0df4ce 451 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GTHT12_RS12550 22583805af663e28e4dcb226df0df4ce 451 SUPERFAMILY SSF56059 83 349 3.87E-74 T 06-07-2017 GTHT12_RS12550 22583805af663e28e4dcb226df0df4ce 451 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 323 2.3E-86 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GTHT12_RS12550 22583805af663e28e4dcb226df0df4ce 451 Gene3D G3DSA:3.30.1490.20 129 202 3.0E-30 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GTHT12_RS18165 0ddcf66a38a756c6645baa71d7709e86 95 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 5.8E-32 T 06-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS18165 0ddcf66a38a756c6645baa71d7709e86 95 Pfam PF01250 Ribosomal protein S6 3 92 3.6E-32 T 06-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS18165 0ddcf66a38a756c6645baa71d7709e86 95 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 23.983 T 06-07-2017 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 GTHT12_RS18165 0ddcf66a38a756c6645baa71d7709e86 95 SUPERFAMILY SSF54995 2 94 1.57E-35 T 06-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS18165 0ddcf66a38a756c6645baa71d7709e86 95 Gene3D G3DSA:3.30.70.60 2 95 4.2E-38 T 06-07-2017 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 GTHT12_RS11020 292e0f0e323ef03bd33d159f03492566 333 Pfam PF00005 ABC transporter 44 194 9.5E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS11020 292e0f0e323ef03bd33d159f03492566 333 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 244 331 4.9E-30 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 GTHT12_RS11020 292e0f0e323ef03bd33d159f03492566 333 Gene3D G3DSA:3.40.50.300 16 268 5.1E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11020 292e0f0e323ef03bd33d159f03492566 333 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS11020 292e0f0e323ef03bd33d159f03492566 333 SMART SM00382 52 244 4.1E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS11020 292e0f0e323ef03bd33d159f03492566 333 SUPERFAMILY SSF52540 17 266 5.92E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11020 292e0f0e323ef03bd33d159f03492566 333 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 246 311 1.3E-19 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 GTHT12_RS16420 f5c68dff17563101cc0780478efac51a 137 SUPERFAMILY SSF47413 1 67 6.66E-22 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS16420 f5c68dff17563101cc0780478efac51a 137 Pfam PF01381 Helix-turn-helix 9 63 4.8E-20 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GTHT12_RS16420 f5c68dff17563101cc0780478efac51a 137 Gene3D G3DSA:1.10.260.40 1 67 3.9E-27 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS16420 f5c68dff17563101cc0780478efac51a 137 SMART SM00530 8 63 2.1E-19 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GTHT12_RS00545 8629befe9868e061617c57fa6b500f62 489 SUPERFAMILY SSF52374 5 317 2.0E-114 T 06-07-2017 GTHT12_RS00545 8629befe9868e061617c57fa6b500f62 489 Gene3D G3DSA:1.10.1160.10 248 333 2.3E-34 T 06-07-2017 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 GTHT12_RS00545 8629befe9868e061617c57fa6b500f62 489 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 324 1.9E-135 T 06-07-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 GTHT12_RS00545 8629befe9868e061617c57fa6b500f62 489 SUPERFAMILY SSF48163 299 485 7.46E-50 T 06-07-2017 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 GTHT12_RS00545 8629befe9868e061617c57fa6b500f62 489 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 5 485 1.9E-187 T 06-07-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 GTHT12_RS00545 8629befe9868e061617c57fa6b500f62 489 Gene3D G3DSA:1.10.10.350 388 485 1.9E-22 T 06-07-2017 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 GTHT12_RS00545 8629befe9868e061617c57fa6b500f62 489 PRINTS PR00987 Glutamyl-tRNA synthetase signature 195 205 3.9E-28 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 GTHT12_RS00545 8629befe9868e061617c57fa6b500f62 489 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 3.9E-28 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 GTHT12_RS00545 8629befe9868e061617c57fa6b500f62 489 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 3.9E-28 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 GTHT12_RS00545 8629befe9868e061617c57fa6b500f62 489 PRINTS PR00987 Glutamyl-tRNA synthetase signature 211 219 3.9E-28 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 GTHT12_RS00545 8629befe9868e061617c57fa6b500f62 489 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 3.9E-28 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 GTHT12_RS00545 8629befe9868e061617c57fa6b500f62 489 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 5 485 35.49 T 06-07-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 GTHT12_RS00545 8629befe9868e061617c57fa6b500f62 489 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS00545 8629befe9868e061617c57fa6b500f62 489 Gene3D G3DSA:3.90.800.10 70 196 2.9E-44 T 06-07-2017 GTHT12_RS00545 8629befe9868e061617c57fa6b500f62 489 Gene3D G3DSA:3.40.50.620 197 246 1.2E-50 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS00545 8629befe9868e061617c57fa6b500f62 489 Gene3D G3DSA:3.40.50.620 5 69 1.2E-50 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS16660 abe3332fae1d4d12917cf2c76498e5ea 496 SUPERFAMILY SSF52540 3 228 1.38E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16660 abe3332fae1d4d12917cf2c76498e5ea 496 Pfam PF00005 ABC transporter 20 171 4.4E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS16660 abe3332fae1d4d12917cf2c76498e5ea 496 Pfam PF00005 ABC transporter 271 424 1.4E-21 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS16660 abe3332fae1d4d12917cf2c76498e5ea 496 Gene3D G3DSA:3.40.50.300 2 229 5.4E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16660 abe3332fae1d4d12917cf2c76498e5ea 496 Gene3D G3DSA:3.40.50.300 261 487 5.2E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16660 abe3332fae1d4d12917cf2c76498e5ea 496 SUPERFAMILY SSF52540 267 484 3.76E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16660 abe3332fae1d4d12917cf2c76498e5ea 496 ProSitePatterns PS00211 ABC transporters family signature. 397 411 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS16660 abe3332fae1d4d12917cf2c76498e5ea 496 SMART SM00382 279 473 4.1E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS16660 abe3332fae1d4d12917cf2c76498e5ea 496 SMART SM00382 29 218 6.0E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS08165 ae86af4c57c7e567afc5e2966e8c08a9 309 SUPERFAMILY SSF103481 48 149 1.44E-10 T 06-07-2017 GTHT12_RS08165 ae86af4c57c7e567afc5e2966e8c08a9 309 SUPERFAMILY SSF103481 206 289 8.11E-8 T 06-07-2017 GTHT12_RS08165 ae86af4c57c7e567afc5e2966e8c08a9 309 Pfam PF00892 EamA-like transporter family 158 289 2.8E-6 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 GTHT12_RS08165 ae86af4c57c7e567afc5e2966e8c08a9 309 Pfam PF00892 EamA-like transporter family 10 148 4.4E-11 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 GTHT12_RS08165 ae86af4c57c7e567afc5e2966e8c08a9 309 TIGRFAM TIGR00688 rarD: protein RarD 9 265 1.4E-83 T 06-07-2017 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 GTHT12_RS00355 a7381622e292a2cc29443b13f1aa08cc 825 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 621 805 9.1E-38 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 GTHT12_RS00355 a7381622e292a2cc29443b13f1aa08cc 825 TIGRFAM TIGR02865 spore_II_E: stage II sporulation protein E 46 805 2.0E-265 T 06-07-2017 IPR014221 Sporulation stage II, protein E KEGG: 04660+3.1.3.16 GTHT12_RS00355 a7381622e292a2cc29443b13f1aa08cc 825 SUPERFAMILY SSF81606 599 806 1.57E-21 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 GTHT12_RS00355 a7381622e292a2cc29443b13f1aa08cc 825 SMART SM00332 585 803 2.8E-4 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 GTHT12_RS00355 a7381622e292a2cc29443b13f1aa08cc 825 SMART SM00331 593 805 1.7E-46 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 GTHT12_RS00355 a7381622e292a2cc29443b13f1aa08cc 825 Gene3D G3DSA:3.60.40.10 708 809 1.2E-8 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 GTHT12_RS07175 3c6e20045440a84076651aad670600e4 389 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 89 138 3.4E-10 T 06-07-2017 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain GTHT12_RS07175 3c6e20045440a84076651aad670600e4 389 Pfam PF01610 Transposase 150 381 2.7E-57 T 06-07-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain GTHT12_RS07175 3c6e20045440a84076651aad670600e4 389 Gene3D G3DSA:3.40.50.150 176 249 6.6E-4 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS04675 3c6e20045440a84076651aad670600e4 389 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 89 138 3.4E-10 T 06-07-2017 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain GTHT12_RS04675 3c6e20045440a84076651aad670600e4 389 Pfam PF01610 Transposase 150 381 2.7E-57 T 06-07-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain GTHT12_RS04675 3c6e20045440a84076651aad670600e4 389 Gene3D G3DSA:3.40.50.150 176 249 6.6E-4 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS01945 6402e8a5d9877c86c72090737e3fd86d 460 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 439 449 - T 06-07-2017 IPR030391 RNA methyltransferase TrmA, conserved site GTHT12_RS01945 6402e8a5d9877c86c72090737e3fd86d 460 Gene3D G3DSA:3.40.50.150 251 454 4.0E-71 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS01945 6402e8a5d9877c86c72090737e3fd86d 460 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 387 418 - T 06-07-2017 IPR030390 RNA methyltransferase TrmA, active site GTHT12_RS01945 6402e8a5d9877c86c72090737e3fd86d 460 Pfam PF01938 TRAM domain 12 63 5.4E-12 T 06-07-2017 IPR002792 TRAM domain GTHT12_RS01945 6402e8a5d9877c86c72090737e3fd86d 460 Gene3D G3DSA:2.40.50.140 2 84 1.3E-32 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS01945 6402e8a5d9877c86c72090737e3fd86d 460 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 278 451 6.9E-20 T 06-07-2017 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 GTHT12_RS01945 6402e8a5d9877c86c72090737e3fd86d 460 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 21 449 1.1E-187 T 06-07-2017 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 GTHT12_RS01945 6402e8a5d9877c86c72090737e3fd86d 460 SUPERFAMILY SSF53335 72 454 1.01E-96 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS01945 6402e8a5d9877c86c72090737e3fd86d 460 SUPERFAMILY SSF50249 3 65 5.6E-17 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS07280 53447c90b9ad919bd996c7cb3fec92bf 274 PIRSF PIRSF028177 6 274 2.1E-79 T 06-07-2017 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 GTHT12_RS07280 53447c90b9ad919bd996c7cb3fec92bf 274 Gene3D G3DSA:3.40.50.150 14 228 2.6E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS07280 53447c90b9ad919bd996c7cb3fec92bf 274 Pfam PF04072 Leucine carboxyl methyltransferase 36 178 1.4E-15 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 GTHT12_RS07280 53447c90b9ad919bd996c7cb3fec92bf 274 SUPERFAMILY SSF53335 18 230 2.56E-49 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS09510 fa800337a6bbbbf7052d565ea94ffac0 718 Gene3D G3DSA:1.10.460.10 476 600 2.3E-55 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 GTHT12_RS09510 fa800337a6bbbbf7052d565ea94ffac0 718 Gene3D G3DSA:1.10.460.10 160 219 2.3E-55 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 GTHT12_RS09510 fa800337a6bbbbf7052d565ea94ffac0 718 SMART SM00437 274 552 2.7E-82 T 06-07-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 GTHT12_RS09510 fa800337a6bbbbf7052d565ea94ffac0 718 Pfam PF01131 DNA topoisomerase 158 587 7.0E-122 T 06-07-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 GTHT12_RS09510 fa800337a6bbbbf7052d565ea94ffac0 718 SUPERFAMILY SSF56712 1 600 9.81E-175 T 06-07-2017 IPR023405 DNA topoisomerase, type IA, core domain GTHT12_RS09510 fa800337a6bbbbf7052d565ea94ffac0 718 SMART SM00493 1 130 3.1E-13 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS09510 fa800337a6bbbbf7052d565ea94ffac0 718 Gene3D G3DSA:3.40.50.140 1 153 1.4E-42 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS09510 fa800337a6bbbbf7052d565ea94ffac0 718 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 311 325 - T 06-07-2017 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 GTHT12_RS09510 fa800337a6bbbbf7052d565ea94ffac0 718 Pfam PF13342 C-terminal repeat of topoisomerase 657 716 3.7E-21 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat GTHT12_RS09510 fa800337a6bbbbf7052d565ea94ffac0 718 Gene3D G3DSA:2.70.20.10 364 475 3.4E-36 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 GTHT12_RS09510 fa800337a6bbbbf7052d565ea94ffac0 718 Gene3D G3DSA:2.70.20.10 220 253 3.4E-36 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 GTHT12_RS09510 fa800337a6bbbbf7052d565ea94ffac0 718 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 515 529 3.3E-25 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS09510 fa800337a6bbbbf7052d565ea94ffac0 718 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 316 325 3.3E-25 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS09510 fa800337a6bbbbf7052d565ea94ffac0 718 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 104 117 3.3E-25 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS09510 fa800337a6bbbbf7052d565ea94ffac0 718 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 195 213 3.3E-25 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS09510 fa800337a6bbbbf7052d565ea94ffac0 718 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 398 414 3.3E-25 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS09510 fa800337a6bbbbf7052d565ea94ffac0 718 Pfam PF01751 Toprim domain 3 138 2.1E-10 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS09510 fa800337a6bbbbf7052d565ea94ffac0 718 SMART SM00436 130 225 4.7E-34 T 06-07-2017 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 GTHT12_RS09510 fa800337a6bbbbf7052d565ea94ffac0 718 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 712 5.1E-190 T 06-07-2017 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 GTHT12_RS10185 72de98a4bbd155a0d0a1088446388bf0 598 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 492 596 1.3E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS10185 72de98a4bbd155a0d0a1088446388bf0 598 Pfam PF02743 Cache domain 52 292 2.1E-20 T 06-07-2017 IPR033479 Double Cache domain 1 GTHT12_RS10185 72de98a4bbd155a0d0a1088446388bf0 598 SUPERFAMILY SSF55874 447 594 2.23E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS10185 72de98a4bbd155a0d0a1088446388bf0 598 PRINTS PR00344 Bacterial sensor protein C-terminal signature 524 538 7.7E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS10185 72de98a4bbd155a0d0a1088446388bf0 598 PRINTS PR00344 Bacterial sensor protein C-terminal signature 554 572 7.7E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS10185 72de98a4bbd155a0d0a1088446388bf0 598 PRINTS PR00344 Bacterial sensor protein C-terminal signature 581 594 7.7E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS10185 72de98a4bbd155a0d0a1088446388bf0 598 Gene3D G3DSA:3.30.450.20 177 307 7.6E-11 T 06-07-2017 GTHT12_RS10185 72de98a4bbd155a0d0a1088446388bf0 598 Pfam PF06580 Histidine kinase 394 472 2.7E-24 T 06-07-2017 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 GTHT12_RS10185 72de98a4bbd155a0d0a1088446388bf0 598 SMART SM00387 483 597 2.4E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS10185 72de98a4bbd155a0d0a1088446388bf0 598 Gene3D G3DSA:3.30.565.10 443 596 1.5E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS17705 3c3a4f8f2e0c56c6a8bed521f819f3de 275 Gene3D G3DSA:3.40.50.150 57 274 3.6E-84 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS17705 3c3a4f8f2e0c56c6a8bed521f819f3de 275 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 79 92 - T 06-07-2017 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 GTHT12_RS17705 3c3a4f8f2e0c56c6a8bed521f819f3de 275 Pfam PF01564 Spermine/spermidine synthase 4 236 3.6E-87 T 06-07-2017 GTHT12_RS17705 3c3a4f8f2e0c56c6a8bed521f819f3de 275 TIGRFAM TIGR00417 speE: spermidine synthase 4 269 7.1E-119 T 06-07-2017 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 GTHT12_RS17705 3c3a4f8f2e0c56c6a8bed521f819f3de 275 SUPERFAMILY SSF53335 3 274 1.27E-87 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS17705 3c3a4f8f2e0c56c6a8bed521f819f3de 275 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 3 275 41.798 T 06-07-2017 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 GTHT12_RS17705 3c3a4f8f2e0c56c6a8bed521f819f3de 275 Gene3D G3DSA:2.30.140.10 1 55 1.1E-20 T 06-07-2017 GTHT12_RS17215 56faaa9adb9660d67fbb0942b94627c9 580 Gene3D G3DSA:3.30.310.50 482 575 2.1E-23 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS17215 56faaa9adb9660d67fbb0942b94627c9 580 Gene3D G3DSA:3.40.120.10 324 455 7.0E-37 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS17215 56faaa9adb9660d67fbb0942b94627c9 580 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 298 313 2.0E-7 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS17215 56faaa9adb9660d67fbb0942b94627c9 580 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 231 250 2.0E-7 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS17215 56faaa9adb9660d67fbb0942b94627c9 580 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 139 153 2.0E-7 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS17215 56faaa9adb9660d67fbb0942b94627c9 580 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 43 181 7.5E-42 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS17215 56faaa9adb9660d67fbb0942b94627c9 580 SUPERFAMILY SSF55957 448 483 5.1E-15 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS17215 56faaa9adb9660d67fbb0942b94627c9 580 SUPERFAMILY SSF55957 515 574 5.1E-15 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS17215 56faaa9adb9660d67fbb0942b94627c9 580 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 326 453 4.1E-24 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS17215 56faaa9adb9660d67fbb0942b94627c9 580 SUPERFAMILY SSF53738 306 457 3.45E-34 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS17215 56faaa9adb9660d67fbb0942b94627c9 580 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 06-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS17215 56faaa9adb9660d67fbb0942b94627c9 580 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 486 559 5.0E-9 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS17215 56faaa9adb9660d67fbb0942b94627c9 580 SUPERFAMILY SSF53738 29 237 2.71E-48 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS17215 56faaa9adb9660d67fbb0942b94627c9 580 Gene3D G3DSA:3.40.120.10 232 317 3.7E-21 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS17215 56faaa9adb9660d67fbb0942b94627c9 580 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 210 314 1.7E-22 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS17215 56faaa9adb9660d67fbb0942b94627c9 580 SUPERFAMILY SSF53738 208 317 2.5E-20 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS17215 56faaa9adb9660d67fbb0942b94627c9 580 Gene3D G3DSA:3.40.120.10 22 217 2.6E-61 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS09985 71f0e34e262e51acfe231e99149e2a14 564 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 289 487 9.3E-43 T 06-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 GTHT12_RS09985 71f0e34e262e51acfe231e99149e2a14 564 SUPERFAMILY SSF53067 4 282 2.38E-49 T 06-07-2017 GTHT12_RS09985 71f0e34e262e51acfe231e99149e2a14 564 SUPERFAMILY SSF53067 281 537 8.42E-57 T 06-07-2017 GTHT12_RS09985 71f0e34e262e51acfe231e99149e2a14 564 Gene3D G3DSA:3.30.420.40 281 533 7.1E-54 T 06-07-2017 GTHT12_RS09985 71f0e34e262e51acfe231e99149e2a14 564 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 277 1.3E-20 T 06-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 GTHT12_RS09985 71f0e34e262e51acfe231e99149e2a14 564 Hamap MF_00520 Ribulokinase [araB]. 3 548 57.195 T 06-07-2017 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 GTHT12_RS09985 71f0e34e262e51acfe231e99149e2a14 564 TIGRFAM TIGR01234 L-ribulokinase: ribulokinase 4 541 1.4E-230 T 06-07-2017 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 GTHT12_RS09985 71f0e34e262e51acfe231e99149e2a14 564 PIRSF PIRSF000538 3 538 4.8E-70 T 06-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 GTHT12_RS09985 71f0e34e262e51acfe231e99149e2a14 564 Gene3D G3DSA:3.30.420.40 2 279 3.2E-52 T 06-07-2017 GTHT12_RS02995 272183b8fd738bd26454a468cf6a2afb 340 Pfam PF00005 ABC transporter 26 184 3.5E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS02995 272183b8fd738bd26454a468cf6a2afb 340 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 300 1.2E-19 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 GTHT12_RS02995 272183b8fd738bd26454a468cf6a2afb 340 Gene3D G3DSA:3.40.50.300 4 258 4.0E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS02995 272183b8fd738bd26454a468cf6a2afb 340 SUPERFAMILY SSF52540 5 255 7.31E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS02995 272183b8fd738bd26454a468cf6a2afb 340 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS02995 272183b8fd738bd26454a468cf6a2afb 340 SMART SM00382 34 234 6.0E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS02995 272183b8fd738bd26454a468cf6a2afb 340 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 321 6.0E-29 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 GTHT12_RS01485 899b8831059ace267a7a11c59b989b6b 540 Gene3D G3DSA:1.10.560.10 366 515 9.7E-45 T 06-07-2017 IPR027413 GroEL-like equatorial domain GTHT12_RS01485 899b8831059ace267a7a11c59b989b6b 540 SUPERFAMILY SSF48592 404 518 2.14E-82 T 06-07-2017 GTHT12_RS01485 899b8831059ace267a7a11c59b989b6b 540 SUPERFAMILY SSF48592 5 133 2.14E-82 T 06-07-2017 GTHT12_RS01485 899b8831059ace267a7a11c59b989b6b 540 Gene3D G3DSA:1.10.560.10 3 194 7.8E-53 T 06-07-2017 IPR027413 GroEL-like equatorial domain GTHT12_RS01485 899b8831059ace267a7a11c59b989b6b 540 SUPERFAMILY SSF52029 183 374 3.44E-86 T 06-07-2017 IPR027409 GroEL-like apical domain GTHT12_RS01485 899b8831059ace267a7a11c59b989b6b 540 PRINTS PR00298 60kDa chaperonin signature 348 373 1.9E-73 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 GTHT12_RS01485 899b8831059ace267a7a11c59b989b6b 540 PRINTS PR00298 60kDa chaperonin signature 396 417 1.9E-73 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 GTHT12_RS01485 899b8831059ace267a7a11c59b989b6b 540 PRINTS PR00298 60kDa chaperonin signature 26 52 1.9E-73 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 GTHT12_RS01485 899b8831059ace267a7a11c59b989b6b 540 PRINTS PR00298 60kDa chaperonin signature 266 289 1.9E-73 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 GTHT12_RS01485 899b8831059ace267a7a11c59b989b6b 540 PRINTS PR00298 60kDa chaperonin signature 82 109 1.9E-73 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 GTHT12_RS01485 899b8831059ace267a7a11c59b989b6b 540 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 1.9E-107 T 06-07-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 GTHT12_RS01485 899b8831059ace267a7a11c59b989b6b 540 Gene3D G3DSA:3.50.7.10 195 365 1.3E-98 T 06-07-2017 IPR027409 GroEL-like apical domain GTHT12_RS01485 899b8831059ace267a7a11c59b989b6b 540 SUPERFAMILY SSF54849 136 204 2.98E-26 T 06-07-2017 GTHT12_RS01485 899b8831059ace267a7a11c59b989b6b 540 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 06-07-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 GTHT12_RS01485 899b8831059ace267a7a11c59b989b6b 540 Hamap MF_00600 60 kDa chaperonin [groL]. 1 539 43.174 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 GTHT12_RS01485 899b8831059ace267a7a11c59b989b6b 540 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 9.1E-263 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 GTHT12_RS00820 1dbc38c786d2153b8e3e690c75335b8f 253 Gene3D G3DSA:3.30.70.580 2 107 1.2E-36 T 06-07-2017 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS00820 1dbc38c786d2153b8e3e690c75335b8f 253 Pfam PF01416 tRNA pseudouridine synthase 9 105 7.1E-13 T 06-07-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS00820 1dbc38c786d2153b8e3e690c75335b8f 253 Pfam PF01416 tRNA pseudouridine synthase 148 247 1.2E-31 T 06-07-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS00820 1dbc38c786d2153b8e3e690c75335b8f 253 SUPERFAMILY SSF55120 3 249 8.2E-89 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS00820 1dbc38c786d2153b8e3e690c75335b8f 253 Gene3D G3DSA:3.30.70.660 109 244 5.1E-47 T 06-07-2017 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS00820 1dbc38c786d2153b8e3e690c75335b8f 253 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 3 241 2.5E-68 T 06-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS00820 1dbc38c786d2153b8e3e690c75335b8f 253 PIRSF PIRSF001430 2 252 6.3E-85 T 06-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS00820 1dbc38c786d2153b8e3e690c75335b8f 253 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 3 246 36.843 T 06-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS16500 927472e919c214e92f5c7eca1c4ee0c2 513 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 476 491 2.0E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 GTHT12_RS16500 927472e919c214e92f5c7eca1c4ee0c2 513 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 491 507 2.0E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 GTHT12_RS16500 927472e919c214e92f5c7eca1c4ee0c2 513 SMART SM00342 424 507 8.2E-41 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 GTHT12_RS16500 927472e919c214e92f5c7eca1c4ee0c2 513 SUPERFAMILY SSF52172 1 157 7.26E-32 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS16500 927472e919c214e92f5c7eca1c4ee0c2 513 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 461 503 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 GTHT12_RS16500 927472e919c214e92f5c7eca1c4ee0c2 513 Pfam PF12833 Helix-turn-helix domain 430 508 5.6E-26 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 GTHT12_RS16500 927472e919c214e92f5c7eca1c4ee0c2 513 SMART SM00448 1 115 2.6E-23 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS16500 927472e919c214e92f5c7eca1c4ee0c2 513 Gene3D G3DSA:1.10.10.60 404 460 5.5E-23 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS16500 927472e919c214e92f5c7eca1c4ee0c2 513 Gene3D G3DSA:1.10.10.60 461 509 1.9E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS16500 927472e919c214e92f5c7eca1c4ee0c2 513 SUPERFAMILY SSF46689 460 510 1.84E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS16500 927472e919c214e92f5c7eca1c4ee0c2 513 SUPERFAMILY SSF46689 408 458 1.25E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS16500 927472e919c214e92f5c7eca1c4ee0c2 513 Pfam PF00072 Response regulator receiver domain 3 115 1.1E-23 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS16500 927472e919c214e92f5c7eca1c4ee0c2 513 Gene3D G3DSA:3.40.50.2300 1 136 1.6E-32 T 06-07-2017 GTHT12_RS02395 036e0ec2838a4cd5b2eadad2356add6d 335 Gene3D G3DSA:3.30.420.40 6 155 5.1E-29 T 06-07-2017 GTHT12_RS02395 036e0ec2838a4cd5b2eadad2356add6d 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 62 85 4.4E-43 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 GTHT12_RS02395 036e0ec2838a4cd5b2eadad2356add6d 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 42 60 4.4E-43 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 GTHT12_RS02395 036e0ec2838a4cd5b2eadad2356add6d 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 182 202 4.4E-43 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 GTHT12_RS02395 036e0ec2838a4cd5b2eadad2356add6d 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 127 146 4.4E-43 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 GTHT12_RS02395 036e0ec2838a4cd5b2eadad2356add6d 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 295 321 4.4E-43 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 GTHT12_RS02395 036e0ec2838a4cd5b2eadad2356add6d 335 Gene3D G3DSA:3.90.640.10 182 253 2.1E-25 T 06-07-2017 GTHT12_RS02395 036e0ec2838a4cd5b2eadad2356add6d 335 SUPERFAMILY SSF53067 145 324 2.14E-43 T 06-07-2017 GTHT12_RS02395 036e0ec2838a4cd5b2eadad2356add6d 335 Pfam PF06723 MreB/Mbl protein 5 327 1.2E-120 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 GTHT12_RS02395 036e0ec2838a4cd5b2eadad2356add6d 335 SUPERFAMILY SSF53067 6 141 1.18E-27 T 06-07-2017 GTHT12_RS02395 036e0ec2838a4cd5b2eadad2356add6d 335 Gene3D G3DSA:3.30.420.40 258 312 4.5E-26 T 06-07-2017 GTHT12_RS02395 036e0ec2838a4cd5b2eadad2356add6d 335 Gene3D G3DSA:3.30.420.40 156 181 4.5E-26 T 06-07-2017 GTHT12_RS10725 d348d00aca0520291e35ac612fd70e92 380 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 25 134 1.5E-24 T 06-07-2017 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS10725 d348d00aca0520291e35ac612fd70e92 380 Gene3D G3DSA:3.40.192.10 18 157 1.5E-63 T 06-07-2017 GTHT12_RS10725 d348d00aca0520291e35ac612fd70e92 380 Gene3D G3DSA:3.40.50.720 158 351 1.2E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS10725 d348d00aca0520291e35ac612fd70e92 380 PIRSF PIRSF000188 11 368 1.5E-160 T 06-07-2017 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 GTHT12_RS10725 d348d00aca0520291e35ac612fd70e92 380 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 84 97 - T 06-07-2017 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-70614 GTHT12_RS10725 d348d00aca0520291e35ac612fd70e92 380 SUPERFAMILY SSF53223 19 154 1.15E-46 T 06-07-2017 GTHT12_RS10725 d348d00aca0520291e35ac612fd70e92 380 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 186 206 1.6E-18 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS10725 d348d00aca0520291e35ac612fd70e92 380 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 76 90 1.6E-18 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS10725 d348d00aca0520291e35ac612fd70e92 380 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 142 164 1.6E-18 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS10725 d348d00aca0520291e35ac612fd70e92 380 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 301 312 1.6E-18 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS10725 d348d00aca0520291e35ac612fd70e92 380 SMART SM00839 157 366 1.0E-45 T 06-07-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS10725 d348d00aca0520291e35ac612fd70e92 380 SUPERFAMILY SSF51735 151 360 6.11E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS10725 d348d00aca0520291e35ac612fd70e92 380 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 151 347 1.9E-15 T 06-07-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS04380 a42dcb5457ddc328343d522c79998d25 202 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 102 130 - T 06-07-2017 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 GTHT12_RS04380 a42dcb5457ddc328343d522c79998d25 202 Pfam PF01464 Transglycosylase SLT domain 84 190 3.7E-33 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 GTHT12_RS04380 a42dcb5457ddc328343d522c79998d25 202 SUPERFAMILY SSF53955 78 200 1.0E-50 T 06-07-2017 IPR023346 Lysozyme-like domain GTHT12_RS04380 a42dcb5457ddc328343d522c79998d25 202 Gene3D G3DSA:1.10.530.10 64 201 7.5E-52 T 06-07-2017 GTHT12_RS05610 185288d969c97f57f1cbc0d567bba99e 490 Gene3D G3DSA:3.90.100.10 380 488 6.4E-31 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 GTHT12_RS05610 185288d969c97f57f1cbc0d567bba99e 490 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 403 460 2.4E-10 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 GTHT12_RS05610 185288d969c97f57f1cbc0d567bba99e 490 Gene3D G3DSA:3.40.640.10 6 282 3.7E-104 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS05610 185288d969c97f57f1cbc0d567bba99e 490 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 221 235 - T 06-07-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 GTHT12_RS05610 185288d969c97f57f1cbc0d567bba99e 490 SUPERFAMILY SSF55904 341 485 1.7E-40 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 GTHT12_RS05610 185288d969c97f57f1cbc0d567bba99e 490 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 6 370 8.3E-112 T 06-07-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 GTHT12_RS05610 185288d969c97f57f1cbc0d567bba99e 490 SUPERFAMILY SSF53383 6 385 1.36E-98 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS02275 e8ecb31847a8b3c82b8316e29fe7d1f5 546 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 420 439 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 GTHT12_RS02275 e8ecb31847a8b3c82b8316e29fe7d1f5 546 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 384 530 2.8E-42 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 GTHT12_RS02275 e8ecb31847a8b3c82b8316e29fe7d1f5 546 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 330 3.0E-34 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 GTHT12_RS02275 e8ecb31847a8b3c82b8316e29fe7d1f5 546 SUPERFAMILY SSF52518 365 540 2.5E-58 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS02275 e8ecb31847a8b3c82b8316e29fe7d1f5 546 Gene3D G3DSA:3.40.50.970 379 540 1.0E-60 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS02275 e8ecb31847a8b3c82b8316e29fe7d1f5 546 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 11 177 3.1E-58 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 GTHT12_RS02275 e8ecb31847a8b3c82b8316e29fe7d1f5 546 SUPERFAMILY SSF52467 161 355 9.63E-45 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS02275 e8ecb31847a8b3c82b8316e29fe7d1f5 546 Gene3D G3DSA:3.40.50.1220 187 378 4.1E-50 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS02275 e8ecb31847a8b3c82b8316e29fe7d1f5 546 SUPERFAMILY SSF52518 7 190 2.22E-56 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS02275 e8ecb31847a8b3c82b8316e29fe7d1f5 546 Gene3D G3DSA:3.40.50.970 10 185 2.8E-65 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS18515 9e45412cab90dc9bd2b59c7633c89e04 522 Gene3D G3DSA:3.30.420.10 124 286 2.2E-12 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS18515 9e45412cab90dc9bd2b59c7633c89e04 522 Gene3D G3DSA:1.10.10.60 3 32 5.4E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS18515 9e45412cab90dc9bd2b59c7633c89e04 522 Pfam PF02796 Helix-turn-helix domain of resolvase 2 32 1.0E-6 T 06-07-2017 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 GTHT12_RS18515 9e45412cab90dc9bd2b59c7633c89e04 522 Pfam PF00665 Integrase core domain 123 248 2.1E-16 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS18515 9e45412cab90dc9bd2b59c7633c89e04 522 SUPERFAMILY SSF46689 3 98 3.05E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS18515 9e45412cab90dc9bd2b59c7633c89e04 522 SUPERFAMILY SSF53098 124 287 2.28E-13 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS05245 9e45412cab90dc9bd2b59c7633c89e04 522 Gene3D G3DSA:3.30.420.10 124 286 2.2E-12 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS05245 9e45412cab90dc9bd2b59c7633c89e04 522 Gene3D G3DSA:1.10.10.60 3 32 5.4E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS05245 9e45412cab90dc9bd2b59c7633c89e04 522 Pfam PF02796 Helix-turn-helix domain of resolvase 2 32 1.0E-6 T 06-07-2017 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 GTHT12_RS05245 9e45412cab90dc9bd2b59c7633c89e04 522 Pfam PF00665 Integrase core domain 123 248 2.1E-16 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS05245 9e45412cab90dc9bd2b59c7633c89e04 522 SUPERFAMILY SSF46689 3 98 3.05E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS05245 9e45412cab90dc9bd2b59c7633c89e04 522 SUPERFAMILY SSF53098 124 287 2.28E-13 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS18035 9e45412cab90dc9bd2b59c7633c89e04 522 Gene3D G3DSA:3.30.420.10 124 286 2.2E-12 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS18035 9e45412cab90dc9bd2b59c7633c89e04 522 Gene3D G3DSA:1.10.10.60 3 32 5.4E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS18035 9e45412cab90dc9bd2b59c7633c89e04 522 Pfam PF02796 Helix-turn-helix domain of resolvase 2 32 1.0E-6 T 06-07-2017 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 GTHT12_RS18035 9e45412cab90dc9bd2b59c7633c89e04 522 Pfam PF00665 Integrase core domain 123 248 2.1E-16 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS18035 9e45412cab90dc9bd2b59c7633c89e04 522 SUPERFAMILY SSF46689 3 98 3.05E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS18035 9e45412cab90dc9bd2b59c7633c89e04 522 SUPERFAMILY SSF53098 124 287 2.28E-13 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS03015 48313f4f999b0611b9f531c1ec420c7e 299 SUPERFAMILY SSF161098 92 284 4.06E-34 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS03015 48313f4f999b0611b9f531c1ec420c7e 299 Gene3D G3DSA:1.10.3720.10 89 295 4.1E-35 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS03015 48313f4f999b0611b9f531c1ec420c7e 299 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 22 74 1.0E-18 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain GTHT12_RS03015 48313f4f999b0611b9f531c1ec420c7e 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 298 7.9E-35 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS16535 3a5b28b92b538d1fe8373ad0ce4da5f3 262 SUPERFAMILY SSF46689 6 73 5.73E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS16535 3a5b28b92b538d1fe8373ad0ce4da5f3 262 SUPERFAMILY SSF53697 78 229 1.83E-31 T 06-07-2017 GTHT12_RS16535 3a5b28b92b538d1fe8373ad0ce4da5f3 262 Pfam PF01418 Helix-turn-helix domain, rpiR family 10 67 9.1E-15 T 06-07-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 GTHT12_RS16535 3a5b28b92b538d1fe8373ad0ce4da5f3 262 Pfam PF01380 SIS domain 108 217 1.7E-14 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 GTHT12_RS16535 3a5b28b92b538d1fe8373ad0ce4da5f3 262 Gene3D G3DSA:1.10.10.10 6 60 2.0E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS16535 3a5b28b92b538d1fe8373ad0ce4da5f3 262 Gene3D G3DSA:3.40.50.10490 61 236 1.1E-28 T 06-07-2017 GTHT12_RS00440 a372a6958a029b66a4835ad0deece0ff 494 PIRSF PIRSF039101 2 494 2.2E-203 T 06-07-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 GTHT12_RS00440 a372a6958a029b66a4835ad0deece0ff 494 Pfam PF01336 OB-fold nucleic acid binding domain 60 136 2.6E-14 T 06-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 GTHT12_RS00440 a372a6958a029b66a4835ad0deece0ff 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 206 222 5.0E-40 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 GTHT12_RS00440 a372a6958a029b66a4835ad0deece0ff 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 190 200 5.0E-40 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 GTHT12_RS00440 a372a6958a029b66a4835ad0deece0ff 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 376 392 5.0E-40 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 GTHT12_RS00440 a372a6958a029b66a4835ad0deece0ff 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 253 270 5.0E-40 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 GTHT12_RS00440 a372a6958a029b66a4835ad0deece0ff 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 235 248 5.0E-40 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 GTHT12_RS00440 a372a6958a029b66a4835ad0deece0ff 494 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 5 493 3.2E-226 T 06-07-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 GTHT12_RS00440 a372a6958a029b66a4835ad0deece0ff 494 Gene3D G3DSA:2.40.50.140 7 146 1.5E-50 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS00440 a372a6958a029b66a4835ad0deece0ff 494 Gene3D G3DSA:3.30.930.10 148 491 6.4E-130 T 06-07-2017 GTHT12_RS00440 a372a6958a029b66a4835ad0deece0ff 494 SUPERFAMILY SSF55681 153 492 2.3E-125 T 06-07-2017 GTHT12_RS00440 a372a6958a029b66a4835ad0deece0ff 494 Pfam PF00152 tRNA synthetases class II (D, K and N) 154 491 6.1E-85 T 06-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS00440 a372a6958a029b66a4835ad0deece0ff 494 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 12 494 46.368 T 06-07-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 GTHT12_RS00440 a372a6958a029b66a4835ad0deece0ff 494 SUPERFAMILY SSF50249 5 146 5.9E-45 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS00795 491fdb3bf153fcc5b1b0f357e4530f6a 314 SMART SM00662 20 227 5.5E-113 T 06-07-2017 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00795 491fdb3bf153fcc5b1b0f357e4530f6a 314 SUPERFAMILY SSF55257 146 230 1.7E-33 T 06-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00795 491fdb3bf153fcc5b1b0f357e4530f6a 314 SUPERFAMILY SSF55257 5 54 1.7E-33 T 06-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00795 491fdb3bf153fcc5b1b0f357e4530f6a 314 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 221 2.0E-24 T 06-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00795 491fdb3bf153fcc5b1b0f357e4530f6a 314 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 20 313 8.8E-128 T 06-07-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00795 491fdb3bf153fcc5b1b0f357e4530f6a 314 Gene3D G3DSA:1.10.150.20 246 313 3.0E-34 T 06-07-2017 GTHT12_RS00795 491fdb3bf153fcc5b1b0f357e4530f6a 314 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 310 1.0E-25 T 06-07-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00795 491fdb3bf153fcc5b1b0f357e4530f6a 314 SUPERFAMILY SSF47789 247 313 4.19E-25 T 06-07-2017 GTHT12_RS00795 491fdb3bf153fcc5b1b0f357e4530f6a 314 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 240 305 1.7E-29 T 06-07-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00795 491fdb3bf153fcc5b1b0f357e4530f6a 314 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 56 152 1.2E-26 T 06-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00795 491fdb3bf153fcc5b1b0f357e4530f6a 314 Gene3D G3DSA:2.170.120.12 50 170 1.4E-48 T 06-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00795 491fdb3bf153fcc5b1b0f357e4530f6a 314 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 313 38.111 T 06-07-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00795 491fdb3bf153fcc5b1b0f357e4530f6a 314 SUPERFAMILY SSF56553 50 171 8.5E-46 T 06-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS14035 a8271fadfdb28cda846984e565a6ba64 784 SMART SM00463 706 784 5.8E-24 T 06-07-2017 IPR002625 Smr domain GTHT12_RS14035 a8271fadfdb28cda846984e565a6ba64 784 Pfam PF01713 Smr domain 709 784 2.1E-22 T 06-07-2017 IPR002625 Smr domain GTHT12_RS14035 a8271fadfdb28cda846984e565a6ba64 784 Gene3D G3DSA:3.40.50.300 293 513 5.1E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS14035 a8271fadfdb28cda846984e565a6ba64 784 SUPERFAMILY SSF160443 707 784 2.22E-10 T 06-07-2017 IPR002625 Smr domain GTHT12_RS14035 a8271fadfdb28cda846984e565a6ba64 784 SUPERFAMILY SSF48334 22 288 8.76E-28 T 06-07-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 GTHT12_RS14035 a8271fadfdb28cda846984e565a6ba64 784 Pfam PF00488 MutS domain V 331 512 3.7E-35 T 06-07-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 GTHT12_RS14035 a8271fadfdb28cda846984e565a6ba64 784 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 410 426 - T 06-07-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 GTHT12_RS14035 a8271fadfdb28cda846984e565a6ba64 784 TIGRFAM TIGR01069 mutS2: MutS2 family protein 2 784 6.0E-277 T 06-07-2017 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 GTHT12_RS14035 a8271fadfdb28cda846984e565a6ba64 784 SMART SM00533 9 315 1.1E-29 T 06-07-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 GTHT12_RS14035 a8271fadfdb28cda846984e565a6ba64 784 PIRSF PIRSF005814 1 784 1.7E-278 T 06-07-2017 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 GTHT12_RS14035 a8271fadfdb28cda846984e565a6ba64 784 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 783 22.361 T 06-07-2017 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 GTHT12_RS14035 a8271fadfdb28cda846984e565a6ba64 784 SMART SM00534 328 513 4.5E-80 T 06-07-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 GTHT12_RS14035 a8271fadfdb28cda846984e565a6ba64 784 SUPERFAMILY SSF52540 293 512 3.58E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05835 9ff9125b021881385311d300fe1366c3 542 Pfam PF10079 Uncharacterized protein conserved in bacteria (DUF2317) 1 539 1.5E-178 T 06-07-2017 IPR011199 Bacillithiol biosynthesis BshC GTHT12_RS05835 9ff9125b021881385311d300fe1366c3 542 PIRSF PIRSF012535 1 542 7.1E-178 T 06-07-2017 IPR011199 Bacillithiol biosynthesis BshC GTHT12_RS05835 9ff9125b021881385311d300fe1366c3 542 Hamap MF_01867 Putative cysteine ligase BshC [bshC]. 1 542 32.045 T 06-07-2017 IPR011199 Bacillithiol biosynthesis BshC GTHT12_RS05835 9ff9125b021881385311d300fe1366c3 542 TIGRFAM TIGR03998 thiol_BshC: bacillithiol biosynthesis cysteine-adding enzyme BshC 11 540 4.3E-192 T 06-07-2017 IPR011199 Bacillithiol biosynthesis BshC GTHT12_RS10095 20426490aa7f4dbf850df0c4183f49fa 381 Pfam PF00005 ABC transporter 279 343 1.4E-7 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS10095 20426490aa7f4dbf850df0c4183f49fa 381 Pfam PF00005 ABC transporter 24 177 1.9E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS10095 20426490aa7f4dbf850df0c4183f49fa 381 SUPERFAMILY SSF52540 8 234 4.13E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10095 20426490aa7f4dbf850df0c4183f49fa 381 SUPERFAMILY SSF52540 278 368 2.38E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10095 20426490aa7f4dbf850df0c4183f49fa 381 Gene3D G3DSA:3.40.50.300 279 367 4.1E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10095 20426490aa7f4dbf850df0c4183f49fa 381 Gene3D G3DSA:3.40.50.300 5 233 2.7E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10095 20426490aa7f4dbf850df0c4183f49fa 381 SMART SM00382 33 225 5.9E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS05125 3394f811f5f7524d8c93bd0061b64352 217 Gene3D G3DSA:1.10.357.10 23 216 3.8E-35 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 GTHT12_RS05125 3394f811f5f7524d8c93bd0061b64352 217 SUPERFAMILY SSF46689 17 77 2.21E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS05125 3394f811f5f7524d8c93bd0061b64352 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 1.8E-19 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS05125 3394f811f5f7524d8c93bd0061b64352 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 2.2E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS05125 3394f811f5f7524d8c93bd0061b64352 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 2.2E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS05125 3394f811f5f7524d8c93bd0061b64352 217 SUPERFAMILY SSF48498 103 216 1.33E-8 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal GTHT12_RS00400 6c318e4859a4f3341074bde1ca5099e9 473 Pfam PF04715 Anthranilate synthase component I, N terminal region 23 151 1.4E-32 T 06-07-2017 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 GTHT12_RS00400 6c318e4859a4f3341074bde1ca5099e9 473 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 103 455 1.4E-100 T 06-07-2017 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 GTHT12_RS00400 6c318e4859a4f3341074bde1ca5099e9 473 SUPERFAMILY SSF56322 12 459 1.05E-153 T 06-07-2017 IPR005801 ADC synthase GO:0009058 GTHT12_RS00400 6c318e4859a4f3341074bde1ca5099e9 473 Pfam PF00425 chorismate binding enzyme 199 452 4.0E-102 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal GTHT12_RS00400 6c318e4859a4f3341074bde1ca5099e9 473 Gene3D G3DSA:3.60.120.10 13 463 6.2E-167 T 06-07-2017 IPR005801 ADC synthase GO:0009058 GTHT12_RS00400 6c318e4859a4f3341074bde1ca5099e9 473 PRINTS PR00095 Anthranilate synthase component I signature 314 327 2.1E-20 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 GTHT12_RS00400 6c318e4859a4f3341074bde1ca5099e9 473 PRINTS PR00095 Anthranilate synthase component I signature 394 408 2.1E-20 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 GTHT12_RS00400 6c318e4859a4f3341074bde1ca5099e9 473 PRINTS PR00095 Anthranilate synthase component I signature 409 423 2.1E-20 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 GTHT12_RS00400 6c318e4859a4f3341074bde1ca5099e9 473 PRINTS PR00095 Anthranilate synthase component I signature 300 313 2.1E-20 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 GTHT12_RS06815 945049117f1daa6c147b60c56dfffc85 381 Gene3D G3DSA:1.20.140.10 221 379 4.4E-57 T 06-07-2017 GTHT12_RS06815 945049117f1daa6c147b60c56dfffc85 381 SUPERFAMILY SSF47203 229 379 6.6E-48 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS06815 945049117f1daa6c147b60c56dfffc85 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 118 9.1E-35 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS06815 945049117f1daa6c147b60c56dfffc85 381 Gene3D G3DSA:1.10.540.10 5 119 2.7E-38 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS06815 945049117f1daa6c147b60c56dfffc85 381 Gene3D G3DSA:2.40.110.10 122 220 1.1E-44 T 06-07-2017 GTHT12_RS06815 945049117f1daa6c147b60c56dfffc85 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 379 5.1E-44 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS06815 945049117f1daa6c147b60c56dfffc85 381 SUPERFAMILY SSF56645 5 243 2.88E-91 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 GTHT12_RS06815 945049117f1daa6c147b60c56dfffc85 381 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 338 357 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 GTHT12_RS06815 945049117f1daa6c147b60c56dfffc85 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 218 7.1E-28 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 GTHT12_RS06865 e19be752ac1b4bbce449266a8f79a4c2 133 SUPERFAMILY SSF46955 12 98 4.76E-21 T 06-07-2017 IPR009061 Putative DNA-binding domain GTHT12_RS06865 e19be752ac1b4bbce449266a8f79a4c2 133 Pfam PF13411 MerR HTH family regulatory protein 13 79 3.1E-19 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS06865 e19be752ac1b4bbce449266a8f79a4c2 133 ProSitePatterns PS00552 MerR-type HTH domain signature. 15 37 - T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS06865 e19be752ac1b4bbce449266a8f79a4c2 133 Gene3D G3DSA:1.10.1660.10 13 110 3.3E-23 T 06-07-2017 GTHT12_RS06865 e19be752ac1b4bbce449266a8f79a4c2 133 SMART SM00422 12 80 6.8E-28 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS06120 e1e6d3061d8b09e91c006c1a203fe6c6 293 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 39 281 1.1E-83 T 06-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 GTHT12_RS06120 e1e6d3061d8b09e91c006c1a203fe6c6 293 Pfam PF03193 Protein of unknown function, DUF258 59 225 9.9E-62 T 06-07-2017 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 GTHT12_RS06120 e1e6d3061d8b09e91c006c1a203fe6c6 293 Gene3D G3DSA:3.40.50.300 64 223 1.2E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06120 e1e6d3061d8b09e91c006c1a203fe6c6 293 SUPERFAMILY SSF52540 64 291 6.4E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06120 e1e6d3061d8b09e91c006c1a203fe6c6 293 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 2 290 39.386 T 06-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 GTHT12_RS06120 e1e6d3061d8b09e91c006c1a203fe6c6 293 Pfam PF16745 RsgA N-terminal domain 3 56 1.4E-24 T 06-07-2017 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal GTHT12_RS06120 e1e6d3061d8b09e91c006c1a203fe6c6 293 Gene3D G3DSA:1.10.40.50 227 291 2.0E-23 T 06-07-2017 GTHT12_RS06120 e1e6d3061d8b09e91c006c1a203fe6c6 293 SUPERFAMILY SSF50249 1 63 3.64E-16 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS06120 e1e6d3061d8b09e91c006c1a203fe6c6 293 Gene3D G3DSA:2.40.50.140 1 61 5.8E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS02850 6d39d699f6c2fbed28c24bfad2d8b7cf 180 Gene3D G3DSA:1.10.10.10 111 170 4.5E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS02850 6d39d699f6c2fbed28c24bfad2d8b7cf 180 SUPERFAMILY SSF88946 2 99 9.73E-27 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS02850 6d39d699f6c2fbed28c24bfad2d8b7cf 180 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 167 1.4E-31 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS02850 6d39d699f6c2fbed28c24bfad2d8b7cf 180 SUPERFAMILY SSF88659 109 169 3.55E-16 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS02850 6d39d699f6c2fbed28c24bfad2d8b7cf 180 Gene3D G3DSA:1.10.1740.10 2 99 6.6E-29 T 06-07-2017 GTHT12_RS02850 6d39d699f6c2fbed28c24bfad2d8b7cf 180 Pfam PF08281 Sigma-70, region 4 113 165 7.2E-17 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS02850 6d39d699f6c2fbed28c24bfad2d8b7cf 180 Pfam PF04542 Sigma-70 region 2 20 86 1.2E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS12215 51aef0045285fea2d1fcc053a4427445 298 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 6 298 1.5E-102 T 06-07-2017 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 GTHT12_RS12215 51aef0045285fea2d1fcc053a4427445 298 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 298 59.743 T 06-07-2017 IPR023009 Tyrosine recombinase XerC/XerD GTHT12_RS12215 51aef0045285fea2d1fcc053a4427445 298 Pfam PF00589 Phage integrase family 110 284 8.3E-56 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS12215 51aef0045285fea2d1fcc053a4427445 298 Gene3D G3DSA:1.10.443.10 110 291 1.5E-64 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS12215 51aef0045285fea2d1fcc053a4427445 298 Gene3D G3DSA:1.10.150.130 2 98 7.8E-28 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal GTHT12_RS12215 51aef0045285fea2d1fcc053a4427445 298 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 7 298 3.2E-123 T 06-07-2017 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 GTHT12_RS12215 51aef0045285fea2d1fcc053a4427445 298 SUPERFAMILY SSF47823 5 99 2.94E-19 T 06-07-2017 IPR010998 Integrase, Lambda-type, N-terminal GTHT12_RS12215 51aef0045285fea2d1fcc053a4427445 298 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 1 298 62.688 T 06-07-2017 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 GTHT12_RS12215 51aef0045285fea2d1fcc053a4427445 298 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 89 7.5E-24 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 GTHT12_RS12215 51aef0045285fea2d1fcc053a4427445 298 SUPERFAMILY SSF56349 106 296 2.21E-63 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 GTHT12_RS15485 32fdecaf1dbb45e1ac13b736adabfaff 256 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 8 228 4.0E-43 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA GTHT12_RS15485 32fdecaf1dbb45e1ac13b736adabfaff 256 Pfam PF13344 Haloacid dehalogenase-like hydrolase 8 106 5.1E-29 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA GTHT12_RS15485 32fdecaf1dbb45e1ac13b736adabfaff 256 SUPERFAMILY SSF56784 3 253 2.1E-75 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS15485 32fdecaf1dbb45e1ac13b736adabfaff 256 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 4 252 6.2E-119 T 06-07-2017 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 GTHT12_RS15485 32fdecaf1dbb45e1ac13b736adabfaff 256 Pfam PF13242 HAD-hyrolase-like 179 251 2.0E-23 T 06-07-2017 GTHT12_RS15485 32fdecaf1dbb45e1ac13b736adabfaff 256 Gene3D G3DSA:3.40.50.10410 85 178 5.6E-35 T 06-07-2017 IPR023215 Nitrophenylphosphatase-like domain GTHT12_RS15485 32fdecaf1dbb45e1ac13b736adabfaff 256 PIRSF PIRSF000915 1 256 2.8E-63 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA GTHT12_RS15485 32fdecaf1dbb45e1ac13b736adabfaff 256 Gene3D G3DSA:3.40.50.1000 2 80 3.1E-48 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS15485 32fdecaf1dbb45e1ac13b736adabfaff 256 Gene3D G3DSA:3.40.50.1000 179 255 3.1E-48 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS15995 e7818ba99a3175ad93072881243defc4 427 SUPERFAMILY SSF53720 21 420 7.06E-88 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GTHT12_RS15995 e7818ba99a3175ad93072881243defc4 427 Pfam PF00815 Histidinol dehydrogenase 19 420 1.0E-173 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GTHT12_RS15995 e7818ba99a3175ad93072881243defc4 427 PRINTS PR00083 Histidinol dehydrogenase signature 193 218 4.8E-91 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GTHT12_RS15995 e7818ba99a3175ad93072881243defc4 427 PRINTS PR00083 Histidinol dehydrogenase signature 354 372 4.8E-91 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GTHT12_RS15995 e7818ba99a3175ad93072881243defc4 427 PRINTS PR00083 Histidinol dehydrogenase signature 222 243 4.8E-91 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GTHT12_RS15995 e7818ba99a3175ad93072881243defc4 427 PRINTS PR00083 Histidinol dehydrogenase signature 163 189 4.8E-91 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GTHT12_RS15995 e7818ba99a3175ad93072881243defc4 427 PRINTS PR00083 Histidinol dehydrogenase signature 27 51 4.8E-91 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GTHT12_RS15995 e7818ba99a3175ad93072881243defc4 427 PRINTS PR00083 Histidinol dehydrogenase signature 128 154 4.8E-91 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GTHT12_RS15995 e7818ba99a3175ad93072881243defc4 427 PRINTS PR00083 Histidinol dehydrogenase signature 313 338 4.8E-91 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GTHT12_RS15995 e7818ba99a3175ad93072881243defc4 427 PRINTS PR00083 Histidinol dehydrogenase signature 244 263 4.8E-91 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GTHT12_RS15995 e7818ba99a3175ad93072881243defc4 427 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 27 419 8.6E-169 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GTHT12_RS15995 e7818ba99a3175ad93072881243defc4 427 Gene3D G3DSA:3.40.50.1980 22 232 2.1E-83 T 06-07-2017 GTHT12_RS15995 e7818ba99a3175ad93072881243defc4 427 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 222 254 - T 06-07-2017 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 GTHT12_RS15995 e7818ba99a3175ad93072881243defc4 427 PIRSF PIRSF000099 4 423 5.0E-172 T 06-07-2017 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GTHT12_RS15995 e7818ba99a3175ad93072881243defc4 427 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 420 43.336 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 GTHT12_RS14435 05cfe820edbeeb36f59f6a4848ea2666 274 Pfam PF02811 PHP domain 3 154 2.8E-10 T 06-07-2017 IPR004013 PHP domain GO:0003824 GTHT12_RS14435 05cfe820edbeeb36f59f6a4848ea2666 274 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 2 254 3.1E-67 T 06-07-2017 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 GTHT12_RS14435 05cfe820edbeeb36f59f6a4848ea2666 274 SUPERFAMILY SSF89550 153 254 1.79E-34 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 GTHT12_RS14435 05cfe820edbeeb36f59f6a4848ea2666 274 SUPERFAMILY SSF89550 3 125 1.79E-34 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 GTHT12_RS14435 05cfe820edbeeb36f59f6a4848ea2666 274 Gene3D G3DSA:3.20.20.140 3 254 2.5E-23 T 06-07-2017 GTHT12_RS09895 7e23e2667da42bfed55ca543b9d04b77 705 Pfam PF03512 Glycosyl hydrolase family 52 20 439 3.6E-178 T 06-07-2017 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00500+3.2.1.37|KEGG: 00520+3.2.1.37 GTHT12_RS09895 7e23e2667da42bfed55ca543b9d04b77 705 SUPERFAMILY SSF48208 338 606 2.18E-8 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 GTHT12_RS09895 7e23e2667da42bfed55ca543b9d04b77 705 PRINTS PR00845 Glycosyl hydrolase family 52 signature 134 154 4.2E-97 T 06-07-2017 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00500+3.2.1.37|KEGG: 00520+3.2.1.37 GTHT12_RS09895 7e23e2667da42bfed55ca543b9d04b77 705 PRINTS PR00845 Glycosyl hydrolase family 52 signature 420 440 4.2E-97 T 06-07-2017 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00500+3.2.1.37|KEGG: 00520+3.2.1.37 GTHT12_RS09895 7e23e2667da42bfed55ca543b9d04b77 705 PRINTS PR00845 Glycosyl hydrolase family 52 signature 20 47 4.2E-97 T 06-07-2017 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00500+3.2.1.37|KEGG: 00520+3.2.1.37 GTHT12_RS09895 7e23e2667da42bfed55ca543b9d04b77 705 PRINTS PR00845 Glycosyl hydrolase family 52 signature 87 114 4.2E-97 T 06-07-2017 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00500+3.2.1.37|KEGG: 00520+3.2.1.37 GTHT12_RS09895 7e23e2667da42bfed55ca543b9d04b77 705 PRINTS PR00845 Glycosyl hydrolase family 52 signature 261 281 4.2E-97 T 06-07-2017 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00500+3.2.1.37|KEGG: 00520+3.2.1.37 GTHT12_RS09895 7e23e2667da42bfed55ca543b9d04b77 705 PRINTS PR00845 Glycosyl hydrolase family 52 signature 307 333 4.2E-97 T 06-07-2017 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00500+3.2.1.37|KEGG: 00520+3.2.1.37 GTHT12_RS09895 7e23e2667da42bfed55ca543b9d04b77 705 PRINTS PR00845 Glycosyl hydrolase family 52 signature 334 363 4.2E-97 T 06-07-2017 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00500+3.2.1.37|KEGG: 00520+3.2.1.37 GTHT12_RS18445 a48c8e3da2596818500c6fb006afecaa 317 Gene3D G3DSA:3.30.200.20 4 88 7.7E-6 T 06-07-2017 GTHT12_RS18445 a48c8e3da2596818500c6fb006afecaa 317 SUPERFAMILY SSF56112 23 299 8.23E-26 T 06-07-2017 IPR011009 Protein kinase-like domain GTHT12_RS18445 a48c8e3da2596818500c6fb006afecaa 317 Gene3D G3DSA:3.90.1200.10 112 253 1.8E-13 T 06-07-2017 GTHT12_RS18445 a48c8e3da2596818500c6fb006afecaa 317 Pfam PF01636 Phosphotransferase enzyme family 29 251 5.0E-15 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase GTHT12_RS05130 7531f511c442adc76418e4e823511fe2 711 Gene3D G3DSA:1.10.8.60 629 708 1.4E-27 T 06-07-2017 GTHT12_RS05130 7531f511c442adc76418e4e823511fe2 711 SMART SM00382 450 620 8.4E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS05130 7531f511c442adc76418e4e823511fe2 711 SMART SM00382 123 267 2.9E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS05130 7531f511c442adc76418e4e823511fe2 711 Gene3D G3DSA:3.40.50.300 86 264 1.8E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05130 7531f511c442adc76418e4e823511fe2 711 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 484 502 - T 06-07-2017 IPR028299 ClpA/B, conserved site 2 GTHT12_RS05130 7531f511c442adc76418e4e823511fe2 711 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 561 575 8.2E-36 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS05130 7531f511c442adc76418e4e823511fe2 711 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 528 546 8.2E-36 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS05130 7531f511c442adc76418e4e823511fe2 711 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 499 517 8.2E-36 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS05130 7531f511c442adc76418e4e823511fe2 711 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 454 472 8.2E-36 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS05130 7531f511c442adc76418e4e823511fe2 711 SUPERFAMILY SSF52540 399 687 2.03E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05130 7531f511c442adc76418e4e823511fe2 711 Gene3D G3DSA:1.10.8.60 266 348 4.6E-32 T 06-07-2017 GTHT12_RS05130 7531f511c442adc76418e4e823511fe2 711 Gene3D G3DSA:3.40.50.300 403 628 4.6E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05130 7531f511c442adc76418e4e823511fe2 711 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 128 260 4.8E-12 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 GTHT12_RS05130 7531f511c442adc76418e4e823511fe2 711 SUPERFAMILY SSF52540 85 363 5.11E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05130 7531f511c442adc76418e4e823511fe2 711 Pfam PF07724 AAA domain (Cdc48 subfamily) 449 613 1.9E-52 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 GTHT12_RS05130 7531f511c442adc76418e4e823511fe2 711 Pfam PF02151 UvrB/uvrC motif 339 372 8.3E-7 T 06-07-2017 IPR001943 UVR domain GO:0005515 GTHT12_RS05130 7531f511c442adc76418e4e823511fe2 711 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 218 230 - T 06-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 GTHT12_RS05130 7531f511c442adc76418e4e823511fe2 711 SMART SM01086 619 707 2.3E-31 T 06-07-2017 IPR019489 Clp ATPase, C-terminal GTHT12_RS05130 7531f511c442adc76418e4e823511fe2 711 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 619 696 7.6E-23 T 06-07-2017 IPR019489 Clp ATPase, C-terminal GTHT12_RS11545 9bb2c169418a79a7920f678a600612c1 378 SUPERFAMILY SSF53756 9 372 9.07E-87 T 06-07-2017 GTHT12_RS11545 9bb2c169418a79a7920f678a600612c1 378 Gene3D G3DSA:3.40.50.2000 165 349 5.3E-32 T 06-07-2017 GTHT12_RS11545 9bb2c169418a79a7920f678a600612c1 378 TIGRFAM TIGR03999 thiol_BshA: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA 3 371 2.1E-175 T 06-07-2017 IPR023881 N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA GO:0016757|GO:0071793 GTHT12_RS11545 9bb2c169418a79a7920f678a600612c1 378 Pfam PF00534 Glycosyl transferases group 1 188 347 4.5E-42 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 GTHT12_RS11545 9bb2c169418a79a7920f678a600612c1 378 Pfam PF13439 Glycosyltransferase Family 4 13 176 1.4E-24 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 GTHT12_RS02345 c4f5687d89186577032d51c60d8210d7 420 SMART SM00257 49 93 2.7E-17 T 06-07-2017 IPR018392 LysM domain GTHT12_RS02345 c4f5687d89186577032d51c60d8210d7 420 SMART SM00257 3 46 5.2E-12 T 06-07-2017 IPR018392 LysM domain GTHT12_RS02345 c4f5687d89186577032d51c60d8210d7 420 SUPERFAMILY SSF51445 115 316 4.64E-46 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS02345 c4f5687d89186577032d51c60d8210d7 420 SUPERFAMILY SSF51445 375 415 4.64E-46 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS02345 c4f5687d89186577032d51c60d8210d7 420 Gene3D G3DSA:3.10.350.10 49 93 3.1E-15 T 06-07-2017 IPR018392 LysM domain GTHT12_RS02345 c4f5687d89186577032d51c60d8210d7 420 Pfam PF00704 Glycosyl hydrolases family 18 177 400 1.0E-26 T 06-07-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 GTHT12_RS02345 c4f5687d89186577032d51c60d8210d7 420 SMART SM00636 100 403 7.7E-25 T 06-07-2017 IPR011583 Chitinase II GO:0004568|GO:0006032 GTHT12_RS02345 c4f5687d89186577032d51c60d8210d7 420 Pfam PF01476 LysM domain 4 46 5.2E-11 T 06-07-2017 IPR018392 LysM domain GTHT12_RS02345 c4f5687d89186577032d51c60d8210d7 420 Pfam PF01476 LysM domain 50 93 6.5E-13 T 06-07-2017 IPR018392 LysM domain GTHT12_RS02345 c4f5687d89186577032d51c60d8210d7 420 SUPERFAMILY SSF54106 2 46 7.46E-11 T 06-07-2017 IPR018392 LysM domain GTHT12_RS02345 c4f5687d89186577032d51c60d8210d7 420 SUPERFAMILY SSF54106 48 93 1.83E-10 T 06-07-2017 IPR018392 LysM domain GTHT12_RS02345 c4f5687d89186577032d51c60d8210d7 420 Gene3D G3DSA:3.20.20.80 175 402 7.8E-39 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS02345 c4f5687d89186577032d51c60d8210d7 420 Gene3D G3DSA:3.10.350.10 3 46 5.4E-14 T 06-07-2017 IPR018392 LysM domain GTHT12_RS13675 a2fe22b1acd65b7630c5de8ba91dae0c 226 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 175 180 - T 06-07-2017 IPR020891 Uncharacterised protein family UPF0758, conserved site GTHT12_RS13675 a2fe22b1acd65b7630c5de8ba91dae0c 226 SUPERFAMILY SSF102712 156 201 6.67E-6 T 06-07-2017 GTHT12_RS13675 a2fe22b1acd65b7630c5de8ba91dae0c 226 Pfam PF04002 RadC-like JAB domain 105 224 4.6E-48 T 06-07-2017 IPR025657 RadC-like JAB domain GTHT12_RS13675 a2fe22b1acd65b7630c5de8ba91dae0c 226 Gene3D G3DSA:3.40.140.10 102 225 1.9E-51 T 06-07-2017 GTHT12_RS13675 a2fe22b1acd65b7630c5de8ba91dae0c 226 TIGRFAM TIGR00608 radc: DNA repair protein RadC 13 225 1.0E-86 T 06-07-2017 IPR001405 RadC protein GTHT12_RS13675 a2fe22b1acd65b7630c5de8ba91dae0c 226 SUPERFAMILY SSF47781 17 93 1.28E-10 T 06-07-2017 IPR010994 RuvA domain 2-like GTHT12_RS13675 a2fe22b1acd65b7630c5de8ba91dae0c 226 Gene3D G3DSA:1.10.150.20 49 88 7.9E-9 T 06-07-2017 GTHT12_RS09560 88dfe775f0e57d03c6cc00e295a97704 1228 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 768 785 - T 06-07-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 GTHT12_RS09560 88dfe775f0e57d03c6cc00e295a97704 1228 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 1117 1144 - T 06-07-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 GTHT12_RS09560 88dfe775f0e57d03c6cc00e295a97704 1228 Gene3D G3DSA:2.20.25.90 55 101 2.0E-30 T 06-07-2017 GTHT12_RS09560 88dfe775f0e57d03c6cc00e295a97704 1228 Gene3D G3DSA:2.40.40.20 1058 1226 4.2E-40 T 06-07-2017 GTHT12_RS09560 88dfe775f0e57d03c6cc00e295a97704 1228 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 51 69 - T 06-07-2017 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 GTHT12_RS09560 88dfe775f0e57d03c6cc00e295a97704 1228 Pfam PF00384 Molybdopterin oxidoreductase 111 824 1.1E-170 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS09560 88dfe775f0e57d03c6cc00e295a97704 1228 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 9 43 5.0E-12 T 06-07-2017 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.99.4 GTHT12_RS09560 88dfe775f0e57d03c6cc00e295a97704 1228 SUPERFAMILY SSF50692 1074 1226 6.1E-47 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain GTHT12_RS09560 88dfe775f0e57d03c6cc00e295a97704 1228 Gene3D G3DSA:3.40.50.740 583 655 5.8E-54 T 06-07-2017 GTHT12_RS09560 88dfe775f0e57d03c6cc00e295a97704 1228 Gene3D G3DSA:3.40.50.740 690 770 5.8E-54 T 06-07-2017 GTHT12_RS09560 88dfe775f0e57d03c6cc00e295a97704 1228 SMART SM00926 46 108 1.1E-6 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS09560 88dfe775f0e57d03c6cc00e295a97704 1228 Gene3D G3DSA:3.40.50.740 153 214 3.6E-8 T 06-07-2017 GTHT12_RS09560 88dfe775f0e57d03c6cc00e295a97704 1228 SUPERFAMILY SSF53706 13 1064 0.0 T 06-07-2017 GTHT12_RS09560 88dfe775f0e57d03c6cc00e295a97704 1228 Gene3D G3DSA:3.90.55.10 771 825 9.9E-7 T 06-07-2017 GTHT12_RS09560 88dfe775f0e57d03c6cc00e295a97704 1228 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 6 1227 0.0 T 06-07-2017 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 GTHT12_RS09560 88dfe775f0e57d03c6cc00e295a97704 1228 Pfam PF01568 Molydopterin dinucleotide binding domain 1080 1194 7.9E-22 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 GTHT12_RS09560 88dfe775f0e57d03c6cc00e295a97704 1228 Gene3D G3DSA:3.40.228.10 475 582 1.4E-68 T 06-07-2017 GTHT12_RS09560 88dfe775f0e57d03c6cc00e295a97704 1228 Gene3D G3DSA:3.40.228.10 222 340 1.4E-68 T 06-07-2017 GTHT12_RS06305 d53f71e29a7cf2cf72ee22f1b093053a 464 Pfam PF07724 AAA domain (Cdc48 subfamily) 214 350 2.3E-40 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 GTHT12_RS06305 d53f71e29a7cf2cf72ee22f1b093053a 464 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 5 464 2.1E-214 T 06-07-2017 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 GTHT12_RS06305 d53f71e29a7cf2cf72ee22f1b093053a 464 SMART SM00382 50 353 8.0E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS06305 d53f71e29a7cf2cf72ee22f1b093053a 464 Gene3D G3DSA:3.40.50.300 5 111 1.7E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06305 d53f71e29a7cf2cf72ee22f1b093053a 464 Gene3D G3DSA:3.40.50.300 265 352 1.7E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06305 d53f71e29a7cf2cf72ee22f1b093053a 464 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 54 103 2.5E-6 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 GTHT12_RS06305 d53f71e29a7cf2cf72ee22f1b093053a 464 SMART SM01086 356 450 8.7E-26 T 06-07-2017 IPR019489 Clp ATPase, C-terminal GTHT12_RS06305 d53f71e29a7cf2cf72ee22f1b093053a 464 Gene3D G3DSA:1.10.8.10 112 196 2.5E-28 T 06-07-2017 GTHT12_RS06305 d53f71e29a7cf2cf72ee22f1b093053a 464 Gene3D G3DSA:1.10.8.10 233 263 2.5E-28 T 06-07-2017 GTHT12_RS06305 d53f71e29a7cf2cf72ee22f1b093053a 464 Gene3D G3DSA:1.10.8.60 355 464 8.9E-38 T 06-07-2017 GTHT12_RS06305 d53f71e29a7cf2cf72ee22f1b093053a 464 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 2 464 43.934 T 06-07-2017 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 GTHT12_RS06305 d53f71e29a7cf2cf72ee22f1b093053a 464 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 356 431 3.6E-9 T 06-07-2017 IPR019489 Clp ATPase, C-terminal GTHT12_RS06305 d53f71e29a7cf2cf72ee22f1b093053a 464 SUPERFAMILY SSF52540 4 462 1.28E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08220 92285cecfc09e428f31b9149f211a97f 208 Gene3D G3DSA:1.10.10.60 7 50 1.9E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS08220 92285cecfc09e428f31b9149f211a97f 208 SUPERFAMILY SSF46689 5 82 1.8E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS08220 92285cecfc09e428f31b9149f211a97f 208 SUPERFAMILY SSF48498 77 192 7.51E-27 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal GTHT12_RS08220 92285cecfc09e428f31b9149f211a97f 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 1.8E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS08220 92285cecfc09e428f31b9149f211a97f 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 1.8E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS08220 92285cecfc09e428f31b9149f211a97f 208 Gene3D G3DSA:1.10.357.10 51 192 2.4E-45 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 GTHT12_RS08220 92285cecfc09e428f31b9149f211a97f 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 53 1.2E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS01290 5cd2be8b93da1ae706dbe029fd190526 232 SUPERFAMILY SSF53474 5 225 2.92E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS01290 5cd2be8b93da1ae706dbe029fd190526 232 Pfam PF12697 Alpha/beta hydrolase family 5 213 1.5E-13 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 GTHT12_RS01290 5cd2be8b93da1ae706dbe029fd190526 232 Gene3D G3DSA:3.40.50.1820 4 225 3.1E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS01290 5cd2be8b93da1ae706dbe029fd190526 232 PIRSF PIRSF017388 1 229 4.4E-57 T 06-07-2017 IPR012354 Esterase/lipase GO:0052689 GTHT12_RS05275 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF46689 48 133 2.33E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS05275 db5bd28d002f8afc840df5d81ad662bb 417 Gene3D G3DSA:3.30.420.10 147 310 8.1E-37 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS05275 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF53098 148 312 1.2E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS05275 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF13565 Homeodomain-like domain 53 130 8.6E-11 T 06-07-2017 GTHT12_RS05275 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF00665 Integrase core domain 154 269 1.0E-22 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS05275 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF09299 Mu transposase, C-terminal 332 385 1.4E-8 T 06-07-2017 IPR015378 Transposase-like, Mu, C-terminal GTHT12_RS02020 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF46689 48 133 2.33E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS02020 db5bd28d002f8afc840df5d81ad662bb 417 Gene3D G3DSA:3.30.420.10 147 310 8.1E-37 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS02020 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF53098 148 312 1.2E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS02020 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF13565 Homeodomain-like domain 53 130 8.6E-11 T 06-07-2017 GTHT12_RS02020 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF00665 Integrase core domain 154 269 1.0E-22 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS02020 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF09299 Mu transposase, C-terminal 332 385 1.4E-8 T 06-07-2017 IPR015378 Transposase-like, Mu, C-terminal GTHT12_RS02755 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF46689 48 133 2.33E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS02755 db5bd28d002f8afc840df5d81ad662bb 417 Gene3D G3DSA:3.30.420.10 147 310 8.1E-37 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS02755 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF53098 148 312 1.2E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS02755 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF13565 Homeodomain-like domain 53 130 8.6E-11 T 06-07-2017 GTHT12_RS02755 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF00665 Integrase core domain 154 269 1.0E-22 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS02755 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF09299 Mu transposase, C-terminal 332 385 1.4E-8 T 06-07-2017 IPR015378 Transposase-like, Mu, C-terminal GTHT12_RS04625 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF46689 48 133 2.33E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS04625 db5bd28d002f8afc840df5d81ad662bb 417 Gene3D G3DSA:3.30.420.10 147 310 8.1E-37 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS04625 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF53098 148 312 1.2E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS04625 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF13565 Homeodomain-like domain 53 130 8.6E-11 T 06-07-2017 GTHT12_RS04625 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF00665 Integrase core domain 154 269 1.0E-22 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS04625 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF09299 Mu transposase, C-terminal 332 385 1.4E-8 T 06-07-2017 IPR015378 Transposase-like, Mu, C-terminal GTHT12_RS02110 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF46689 48 133 2.33E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS02110 db5bd28d002f8afc840df5d81ad662bb 417 Gene3D G3DSA:3.30.420.10 147 310 8.1E-37 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS02110 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF53098 148 312 1.2E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS02110 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF13565 Homeodomain-like domain 53 130 8.6E-11 T 06-07-2017 GTHT12_RS02110 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF00665 Integrase core domain 154 269 1.0E-22 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS02110 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF09299 Mu transposase, C-terminal 332 385 1.4E-8 T 06-07-2017 IPR015378 Transposase-like, Mu, C-terminal GTHT12_RS11295 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF46689 48 133 2.33E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS11295 db5bd28d002f8afc840df5d81ad662bb 417 Gene3D G3DSA:3.30.420.10 147 310 8.1E-37 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS11295 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF53098 148 312 1.2E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS11295 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF13565 Homeodomain-like domain 53 130 8.6E-11 T 06-07-2017 GTHT12_RS11295 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF00665 Integrase core domain 154 269 1.0E-22 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS11295 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF09299 Mu transposase, C-terminal 332 385 1.4E-8 T 06-07-2017 IPR015378 Transposase-like, Mu, C-terminal GTHT12_RS15085 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF46689 48 133 2.33E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS15085 db5bd28d002f8afc840df5d81ad662bb 417 Gene3D G3DSA:3.30.420.10 147 310 8.1E-37 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS15085 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF53098 148 312 1.2E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS15085 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF13565 Homeodomain-like domain 53 130 8.6E-11 T 06-07-2017 GTHT12_RS15085 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF00665 Integrase core domain 154 269 1.0E-22 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS15085 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF09299 Mu transposase, C-terminal 332 385 1.4E-8 T 06-07-2017 IPR015378 Transposase-like, Mu, C-terminal GTHT12_RS08995 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF46689 48 133 2.33E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS08995 db5bd28d002f8afc840df5d81ad662bb 417 Gene3D G3DSA:3.30.420.10 147 310 8.1E-37 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS08995 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF53098 148 312 1.2E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS08995 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF13565 Homeodomain-like domain 53 130 8.6E-11 T 06-07-2017 GTHT12_RS08995 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF00665 Integrase core domain 154 269 1.0E-22 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS08995 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF09299 Mu transposase, C-terminal 332 385 1.4E-8 T 06-07-2017 IPR015378 Transposase-like, Mu, C-terminal GTHT12_RS03085 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF46689 48 133 2.33E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS03085 db5bd28d002f8afc840df5d81ad662bb 417 Gene3D G3DSA:3.30.420.10 147 310 8.1E-37 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS03085 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF53098 148 312 1.2E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS03085 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF13565 Homeodomain-like domain 53 130 8.6E-11 T 06-07-2017 GTHT12_RS03085 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF00665 Integrase core domain 154 269 1.0E-22 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS03085 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF09299 Mu transposase, C-terminal 332 385 1.4E-8 T 06-07-2017 IPR015378 Transposase-like, Mu, C-terminal GTHT12_RS17005 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF46689 48 133 2.33E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS17005 db5bd28d002f8afc840df5d81ad662bb 417 Gene3D G3DSA:3.30.420.10 147 310 8.1E-37 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS17005 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF53098 148 312 1.2E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS17005 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF13565 Homeodomain-like domain 53 130 8.6E-11 T 06-07-2017 GTHT12_RS17005 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF00665 Integrase core domain 154 269 1.0E-22 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS17005 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF09299 Mu transposase, C-terminal 332 385 1.4E-8 T 06-07-2017 IPR015378 Transposase-like, Mu, C-terminal GTHT12_RS07190 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF46689 48 133 2.33E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS07190 db5bd28d002f8afc840df5d81ad662bb 417 Gene3D G3DSA:3.30.420.10 147 310 8.1E-37 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS07190 db5bd28d002f8afc840df5d81ad662bb 417 SUPERFAMILY SSF53098 148 312 1.2E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS07190 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF13565 Homeodomain-like domain 53 130 8.6E-11 T 06-07-2017 GTHT12_RS07190 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF00665 Integrase core domain 154 269 1.0E-22 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS07190 db5bd28d002f8afc840df5d81ad662bb 417 Pfam PF09299 Mu transposase, C-terminal 332 385 1.4E-8 T 06-07-2017 IPR015378 Transposase-like, Mu, C-terminal GTHT12_RS16480 e5d4019077871e7f59c72a7dfb3a93fa 290 SUPERFAMILY SSF53067 1 288 3.89E-50 T 06-07-2017 GTHT12_RS16480 e5d4019077871e7f59c72a7dfb3a93fa 290 Gene3D G3DSA:3.30.420.40 104 289 6.4E-73 T 06-07-2017 GTHT12_RS16480 e5d4019077871e7f59c72a7dfb3a93fa 290 Gene3D G3DSA:3.30.420.40 1 103 6.7E-37 T 06-07-2017 GTHT12_RS16480 e5d4019077871e7f59c72a7dfb3a93fa 290 Pfam PF00480 ROK family 4 286 1.2E-74 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 GTHT12_RS16480 e5d4019077871e7f59c72a7dfb3a93fa 290 ProSitePatterns PS01125 ROK family signature. 129 154 - T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 GTHT12_RS13035 bc918291b8c796735ef6973b6a50b0a5 47 Pfam PF14006 YqzL-like protein 3 46 1.2E-20 T 06-07-2017 IPR025617 YqzL-like protein GTHT12_RS13490 30ce28aaf238068dd90164f39c11c7c6 785 SUPERFAMILY SSF64182 57 451 1.29E-123 T 06-07-2017 GTHT12_RS13490 30ce28aaf238068dd90164f39c11c7c6 785 Pfam PF01368 DHH family 83 226 3.0E-12 T 06-07-2017 IPR001667 DDH domain GTHT12_RS13490 30ce28aaf238068dd90164f39c11c7c6 785 Gene3D G3DSA:3.40.50.10260 314 392 2.8E-6 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 GTHT12_RS13490 30ce28aaf238068dd90164f39c11c7c6 785 Pfam PF02272 DHHA1 domain 373 438 3.3E-13 T 06-07-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 GTHT12_RS13490 30ce28aaf238068dd90164f39c11c7c6 785 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 28 559 7.9E-178 T 06-07-2017 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 GTHT12_RS13490 30ce28aaf238068dd90164f39c11c7c6 785 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 568 770 2.1E-65 T 06-07-2017 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal GTHT12_RS06755 92d5cf40b8f0bc8713ec77ff12f8e1a3 143 PIRSF PIRSF021287 1 123 2.0E-53 T 06-07-2017 IPR016783 Biofilm formation YmcA GTHT12_RS06755 92d5cf40b8f0bc8713ec77ff12f8e1a3 143 SUPERFAMILY SSF158622 4 123 4.97E-37 T 06-07-2017 IPR023378 YheA/YmcA-like domain GTHT12_RS06755 92d5cf40b8f0bc8713ec77ff12f8e1a3 143 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 9 113 4.0E-25 T 06-07-2017 IPR010368 Control of competence regulator ComK, YlbF/YmcA GTHT12_RS06755 92d5cf40b8f0bc8713ec77ff12f8e1a3 143 Gene3D G3DSA:1.20.1500.10 2 123 1.2E-45 T 06-07-2017 IPR023378 YheA/YmcA-like domain GTHT12_RS00550 43eca94d228918333f47f54ab0b95f03 224 PIRSF PIRSF000441 1 221 5.2E-89 T 06-07-2017 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 GTHT12_RS00550 43eca94d228918333f47f54ab0b95f03 224 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 06-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 GTHT12_RS00550 43eca94d228918333f47f54ab0b95f03 224 Pfam PF06426 Serine acetyltransferase, N-terminal 3 35 1.4E-4 T 06-07-2017 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 GTHT12_RS00550 43eca94d228918333f47f54ab0b95f03 224 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 6 166 1.2E-80 T 06-07-2017 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 GTHT12_RS00550 43eca94d228918333f47f54ab0b95f03 224 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 71 108 1.1E-5 T 06-07-2017 IPR001451 Hexapeptide repeat GTHT12_RS00550 43eca94d228918333f47f54ab0b95f03 224 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 151 8.1E-10 T 06-07-2017 IPR001451 Hexapeptide repeat GTHT12_RS00550 43eca94d228918333f47f54ab0b95f03 224 Gene3D G3DSA:2.160.10.10 59 212 2.0E-42 T 06-07-2017 GTHT12_RS00550 43eca94d228918333f47f54ab0b95f03 224 SUPERFAMILY SSF51161 3 168 2.36E-60 T 06-07-2017 IPR011004 Trimeric LpxA-like GTHT12_RS00550 43eca94d228918333f47f54ab0b95f03 224 Gene3D G3DSA:1.10.3130.10 1 58 2.1E-28 T 06-07-2017 GTHT12_RS01180 ce89c79e7a43c735f3eb15d771dd16f1 386 Gene3D G3DSA:1.10.540.10 1 120 1.8E-37 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS01180 ce89c79e7a43c735f3eb15d771dd16f1 386 SUPERFAMILY SSF47203 227 382 3.14E-55 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS01180 ce89c79e7a43c735f3eb15d771dd16f1 386 Gene3D G3DSA:1.20.140.10 218 383 4.2E-69 T 06-07-2017 GTHT12_RS01180 ce89c79e7a43c735f3eb15d771dd16f1 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 GTHT12_RS01180 ce89c79e7a43c735f3eb15d771dd16f1 386 SUPERFAMILY SSF56645 2 242 1.31E-85 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 GTHT12_RS01180 ce89c79e7a43c735f3eb15d771dd16f1 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 118 1.5E-33 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS01180 ce89c79e7a43c735f3eb15d771dd16f1 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 216 2.5E-27 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 GTHT12_RS01180 ce89c79e7a43c735f3eb15d771dd16f1 386 Gene3D G3DSA:2.40.110.10 121 217 3.7E-41 T 06-07-2017 GTHT12_RS01180 ce89c79e7a43c735f3eb15d771dd16f1 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 376 1.6E-49 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS13170 80100ef00790e2a5a15f0dc7ddc95a5b 339 Pfam PF06144 DNA polymerase III, delta subunit 18 193 1.1E-46 T 06-07-2017 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 GTHT12_RS13170 80100ef00790e2a5a15f0dc7ddc95a5b 339 SUPERFAMILY SSF48019 217 334 8.08E-26 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 GTHT12_RS13170 80100ef00790e2a5a15f0dc7ddc95a5b 339 Gene3D G3DSA:1.10.8.60 148 226 7.9E-19 T 06-07-2017 GTHT12_RS13170 80100ef00790e2a5a15f0dc7ddc95a5b 339 Gene3D G3DSA:3.40.50.300 8 140 2.0E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13170 80100ef00790e2a5a15f0dc7ddc95a5b 339 Gene3D G3DSA:1.20.272.20 227 321 4.9E-7 T 06-07-2017 GTHT12_RS13170 80100ef00790e2a5a15f0dc7ddc95a5b 339 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 15 334 2.0E-89 T 06-07-2017 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 GTHT12_RS13170 80100ef00790e2a5a15f0dc7ddc95a5b 339 SUPERFAMILY SSF52540 8 213 1.68E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05855 d3620fada93ce7ae5673024c9af6085c 644 SMART SM00740 579 637 1.7E-13 T 06-07-2017 IPR005543 PASTA domain GTHT12_RS05855 d3620fada93ce7ae5673024c9af6085c 644 Gene3D G3DSA:3.90.1310.10 126 226 1.3E-31 T 06-07-2017 GTHT12_RS05855 d3620fada93ce7ae5673024c9af6085c 644 TIGRFAM TIGR02214 spoVD_pbp: stage V sporulation protein D 13 636 9.7E-265 T 06-07-2017 IPR011927 Stage V sporulation protein D GTHT12_RS05855 d3620fada93ce7ae5673024c9af6085c 644 SUPERFAMILY SSF56601 170 568 5.81E-105 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS05855 d3620fada93ce7ae5673024c9af6085c 644 SUPERFAMILY SSF54184 584 635 3.53E-11 T 06-07-2017 GTHT12_RS05855 d3620fada93ce7ae5673024c9af6085c 644 Pfam PF00905 Penicillin binding protein transpeptidase domain 246 556 7.2E-87 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 GTHT12_RS05855 d3620fada93ce7ae5673024c9af6085c 644 SUPERFAMILY SSF56519 52 219 2.62E-46 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 GTHT12_RS05855 d3620fada93ce7ae5673024c9af6085c 644 Gene3D G3DSA:3.40.710.10 227 566 3.6E-106 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS05855 d3620fada93ce7ae5673024c9af6085c 644 Pfam PF03793 PASTA domain 584 637 4.7E-12 T 06-07-2017 IPR005543 PASTA domain GTHT12_RS05855 d3620fada93ce7ae5673024c9af6085c 644 Pfam PF03717 Penicillin-binding Protein dimerisation domain 56 200 4.1E-24 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 GTHT12_RS06505 05dadf7fb18656bbefc6184f967c8446 264 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 221 247 - T 06-07-2017 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981 GTHT12_RS06505 05dadf7fb18656bbefc6184f967c8446 264 Pfam PF01148 Cytidylyltransferase family 2 262 6.7E-70 T 06-07-2017 GTHT12_RS13555 07d14c6ac6def0060358f61939f57144 247 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 241 38.992 T 06-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS13555 07d14c6ac6def0060358f61939f57144 247 Gene3D G3DSA:1.10.10.200 1 79 1.0E-36 T 06-07-2017 IPR017856 Integrase, N-terminal zinc-binding domain-like GTHT12_RS13555 07d14c6ac6def0060358f61939f57144 247 Pfam PF01709 Transcriptional regulator 5 239 7.8E-101 T 06-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS13555 07d14c6ac6def0060358f61939f57144 247 SUPERFAMILY SSF75625 3 240 2.75E-100 T 06-07-2017 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS13555 07d14c6ac6def0060358f61939f57144 247 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 239 1.8E-108 T 06-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS13555 07d14c6ac6def0060358f61939f57144 247 Gene3D G3DSA:3.30.1270.10 82 134 8.1E-42 T 06-07-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS13555 07d14c6ac6def0060358f61939f57144 247 Gene3D G3DSA:3.30.1270.10 214 242 8.1E-42 T 06-07-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS13555 07d14c6ac6def0060358f61939f57144 247 Gene3D G3DSA:3.30.70.980 135 207 1.0E-26 T 06-07-2017 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS04320 4adf8424ceef08996168e7936cdedd0a 353 Pfam PF00005 ABC transporter 25 183 3.3E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS04320 4adf8424ceef08996168e7936cdedd0a 353 SUPERFAMILY SSF52540 4 254 4.96E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS04320 4adf8424ceef08996168e7936cdedd0a 353 SMART SM00382 33 233 2.8E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS04320 4adf8424ceef08996168e7936cdedd0a 353 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 297 8.8E-16 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 GTHT12_RS04320 4adf8424ceef08996168e7936cdedd0a 353 Gene3D G3DSA:3.40.50.300 3 256 2.1E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS04320 4adf8424ceef08996168e7936cdedd0a 353 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS04320 4adf8424ceef08996168e7936cdedd0a 353 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 318 4.9E-21 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 GTHT12_RS06085 39aa15ca9305997516aeb9ba8085fcd8 801 SUPERFAMILY SSF52540 530 705 7.41E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06085 39aa15ca9305997516aeb9ba8085fcd8 801 SUPERFAMILY SSF52540 258 441 1.77E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06085 39aa15ca9305997516aeb9ba8085fcd8 801 Gene3D G3DSA:3.40.50.300 250 451 4.4E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06085 39aa15ca9305997516aeb9ba8085fcd8 801 Pfam PF00271 Helicase conserved C-terminal domain 573 658 9.5E-8 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS06085 39aa15ca9305997516aeb9ba8085fcd8 801 Gene3D G3DSA:3.40.50.300 524 702 6.2E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06085 39aa15ca9305997516aeb9ba8085fcd8 801 SMART SM00490 562 659 6.3E-8 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS06085 39aa15ca9305997516aeb9ba8085fcd8 801 TIGRFAM TIGR00595 priA: primosomal protein N' 288 798 6.4E-219 T 06-07-2017 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 GTHT12_RS06085 39aa15ca9305997516aeb9ba8085fcd8 801 Hamap MF_00983 Probable primosomal protein N' [priA]. 9 800 25.555 T 06-07-2017 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 GTHT12_RS06085 39aa15ca9305997516aeb9ba8085fcd8 801 SMART SM00487 260 451 1.2E-28 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain GTHT12_RS06085 39aa15ca9305997516aeb9ba8085fcd8 801 Pfam PF04851 Type III restriction enzyme, res subunit 264 427 9.4E-17 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 GTHT12_RS00165 df0c56bec392b60de23e690b11a22c11 478 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 6 361 2.6E-80 T 06-07-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 GTHT12_RS00165 df0c56bec392b60de23e690b11a22c11 478 Gene3D G3DSA:3.40.640.10 6 278 9.5E-103 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS00165 df0c56bec392b60de23e690b11a22c11 478 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 409 456 1.2E-8 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 GTHT12_RS00165 df0c56bec392b60de23e690b11a22c11 478 SUPERFAMILY SSF53383 6 362 1.84E-82 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS00165 df0c56bec392b60de23e690b11a22c11 478 Gene3D G3DSA:3.90.100.10 399 472 2.1E-17 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 GTHT12_RS00165 df0c56bec392b60de23e690b11a22c11 478 SUPERFAMILY SSF55904 337 473 6.15E-22 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 GTHT12_RS03360 a993a29a5f3f0a3e982d35d752039623 450 Pfam PF00571 CBS domain 288 337 4.6E-4 T 06-07-2017 IPR000644 CBS domain GTHT12_RS03360 a993a29a5f3f0a3e982d35d752039623 450 Pfam PF00571 CBS domain 217 269 5.4E-4 T 06-07-2017 IPR000644 CBS domain GTHT12_RS03360 a993a29a5f3f0a3e982d35d752039623 450 Pfam PF01595 Domain of unknown function DUF21 8 201 7.4E-49 T 06-07-2017 IPR002550 Domain of unknown function DUF21 GTHT12_RS03360 a993a29a5f3f0a3e982d35d752039623 450 SUPERFAMILY SSF56176 356 438 3.82E-20 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 GTHT12_RS03360 a993a29a5f3f0a3e982d35d752039623 450 SUPERFAMILY SSF54631 204 340 1.77E-30 T 06-07-2017 GTHT12_RS03360 a993a29a5f3f0a3e982d35d752039623 450 Pfam PF03471 Transporter associated domain 356 427 9.0E-20 T 06-07-2017 IPR005170 Transporter-associated domain GTHT12_RS03360 a993a29a5f3f0a3e982d35d752039623 450 Gene3D G3DSA:3.30.465.10 344 429 5.2E-24 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 GTHT12_RS03360 a993a29a5f3f0a3e982d35d752039623 450 Gene3D G3DSA:3.10.580.10 203 343 2.8E-21 T 06-07-2017 GTHT12_RS03360 a993a29a5f3f0a3e982d35d752039623 450 SMART SM01091 352 429 2.5E-24 T 06-07-2017 IPR005170 Transporter-associated domain GTHT12_RS06525 3de4c2bfcd32eb4a588699abb19c79f0 1434 Pfam PF14579 Helix-hairpin-helix motif 1347 1428 1.6E-10 T 06-07-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS06525 3de4c2bfcd32eb4a588699abb19c79f0 1434 SUPERFAMILY SSF50249 233 318 2.23E-10 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS06525 3de4c2bfcd32eb4a588699abb19c79f0 1434 Gene3D G3DSA:1.10.150.280 1371 1423 3.4E-12 T 06-07-2017 GTHT12_RS06525 3de4c2bfcd32eb4a588699abb19c79f0 1434 Pfam PF02811 PHP domain 334 691 1.4E-53 T 06-07-2017 IPR004013 PHP domain GO:0003824 GTHT12_RS06525 3de4c2bfcd32eb4a588699abb19c79f0 1434 Gene3D G3DSA:3.20.20.140 331 413 9.5E-65 T 06-07-2017 GTHT12_RS06525 3de4c2bfcd32eb4a588699abb19c79f0 1434 Gene3D G3DSA:3.20.20.140 627 793 9.5E-65 T 06-07-2017 GTHT12_RS06525 3de4c2bfcd32eb4a588699abb19c79f0 1434 Gene3D G3DSA:2.40.50.140 231 321 3.0E-8 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS06525 3de4c2bfcd32eb4a588699abb19c79f0 1434 Pfam PF11490 DNA polymerase III polC-type N-terminus II 95 205 1.6E-21 T 06-07-2017 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS06525 3de4c2bfcd32eb4a588699abb19c79f0 1434 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1434 454.971 T 06-07-2017 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS06525 3de4c2bfcd32eb4a588699abb19c79f0 1434 Pfam PF14480 DNA polymerase III polC-type N-terminus I 9 81 9.7E-21 T 06-07-2017 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS06525 3de4c2bfcd32eb4a588699abb19c79f0 1434 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 228 1434 0.0 T 06-07-2017 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS06525 3de4c2bfcd32eb4a588699abb19c79f0 1434 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 411 634 8.9E-59 T 06-07-2017 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS06525 3de4c2bfcd32eb4a588699abb19c79f0 1434 SUPERFAMILY SSF53098 418 874 2.85E-110 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS06525 3de4c2bfcd32eb4a588699abb19c79f0 1434 SMART SM00479 418 584 1.1E-51 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III GTHT12_RS06525 3de4c2bfcd32eb4a588699abb19c79f0 1434 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 822 1240 9.6E-98 T 06-07-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS06525 3de4c2bfcd32eb4a588699abb19c79f0 1434 SUPERFAMILY SSF160975 1373 1410 5.49E-5 T 06-07-2017 GTHT12_RS06525 3de4c2bfcd32eb4a588699abb19c79f0 1434 Pfam PF00929 Exonuclease 420 573 2.2E-39 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III GTHT12_RS06525 3de4c2bfcd32eb4a588699abb19c79f0 1434 Gene3D G3DSA:3.30.420.10 414 590 2.2E-62 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS06525 3de4c2bfcd32eb4a588699abb19c79f0 1434 SMART SM00481 333 400 1.5E-29 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 GTHT12_RS18065 446afab9cbbbe578d439efe420a89f12 212 SUPERFAMILY SSF46894 149 207 4.42E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GTHT12_RS18065 446afab9cbbbe578d439efe420a89f12 212 Pfam PF00072 Response regulator receiver domain 5 116 1.6E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS18065 446afab9cbbbe578d439efe420a89f12 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 4.6E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS18065 446afab9cbbbe578d439efe420a89f12 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 4.6E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS18065 446afab9cbbbe578d439efe420a89f12 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 4.6E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS18065 446afab9cbbbe578d439efe420a89f12 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS18065 446afab9cbbbe578d439efe420a89f12 212 Gene3D G3DSA:3.40.50.2300 2 150 2.4E-34 T 06-07-2017 GTHT12_RS18065 446afab9cbbbe578d439efe420a89f12 212 SUPERFAMILY SSF52172 1 131 3.84E-32 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS18065 446afab9cbbbe578d439efe420a89f12 212 SMART SM00448 3 115 9.2E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS18065 446afab9cbbbe578d439efe420a89f12 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 205 1.2E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS18065 446afab9cbbbe578d439efe420a89f12 212 Gene3D G3DSA:1.10.10.10 151 208 1.6E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS18065 446afab9cbbbe578d439efe420a89f12 212 SMART SM00421 149 206 8.6E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS06495 e9afb62116492714906c607e52946b9c 185 Gene3D G3DSA:1.10.132.20 66 185 1.8E-45 T 06-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 GTHT12_RS06495 e9afb62116492714906c607e52946b9c 185 SUPERFAMILY SSF55194 4 184 9.81E-73 T 06-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 GTHT12_RS06495 e9afb62116492714906c607e52946b9c 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 1.3E-76 T 06-07-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 GTHT12_RS06495 e9afb62116492714906c607e52946b9c 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 28.668 T 06-07-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 GTHT12_RS06495 e9afb62116492714906c607e52946b9c 185 Pfam PF01765 Ribosome recycling factor 20 183 7.0E-66 T 06-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 GTHT12_RS01915 964a34317200e41d7b838863b4067a62 481 SUPERFAMILY SSF53720 3 479 6.54E-169 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GTHT12_RS01915 964a34317200e41d7b838863b4067a62 481 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 GTHT12_RS01915 964a34317200e41d7b838863b4067a62 481 Gene3D G3DSA:3.40.605.10 2 262 5.0E-100 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS01915 964a34317200e41d7b838863b4067a62 481 PIRSF PIRSF036492 27 480 1.4E-85 T 06-07-2017 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 GTHT12_RS01915 964a34317200e41d7b838863b4067a62 481 Pfam PF00171 Aldehyde dehydrogenase family 12 475 6.2E-173 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS01915 964a34317200e41d7b838863b4067a62 481 Gene3D G3DSA:3.40.309.10 263 450 7.3E-68 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 GTHT12_RS06020 c54ad3775d7abcd27ebf1f562a6af2e5 313 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 301 42.156 T 06-07-2017 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 GTHT12_RS06020 c54ad3775d7abcd27ebf1f562a6af2e5 313 Pfam PF01180 Dihydroorotate dehydrogenase 4 285 1.1E-94 T 06-07-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 GTHT12_RS06020 c54ad3775d7abcd27ebf1f562a6af2e5 313 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 302 3.0E-126 T 06-07-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 GTHT12_RS06020 c54ad3775d7abcd27ebf1f562a6af2e5 313 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 40 59 - T 06-07-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 GTHT12_RS06020 c54ad3775d7abcd27ebf1f562a6af2e5 313 PIRSF PIRSF000164 1 303 1.3E-86 T 06-07-2017 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 GTHT12_RS06020 c54ad3775d7abcd27ebf1f562a6af2e5 313 SUPERFAMILY SSF51395 2 301 1.43E-89 T 06-07-2017 GTHT12_RS06020 c54ad3775d7abcd27ebf1f562a6af2e5 313 Gene3D G3DSA:3.20.20.70 1 302 3.4E-99 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS06020 c54ad3775d7abcd27ebf1f562a6af2e5 313 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 239 259 - T 06-07-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 GTHT12_RS06615 ed2d2453065cab0b85e849c227d9d33a 415 SUPERFAMILY SSF53633 3 247 3.14E-70 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase GTHT12_RS06615 ed2d2453065cab0b85e849c227d9d33a 415 PIRSF PIRSF000726 61 407 9.0E-93 T 06-07-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 GTHT12_RS06615 ed2d2453065cab0b85e849c227d9d33a 415 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 402 1.6E-138 T 06-07-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 GTHT12_RS06615 ed2d2453065cab0b85e849c227d9d33a 415 Pfam PF00696 Amino acid kinase family 2 235 1.1E-49 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase GTHT12_RS06615 ed2d2453065cab0b85e849c227d9d33a 415 Pfam PF13840 ACT domain 336 398 2.1E-23 T 06-07-2017 IPR027795 GATS-like ACT domain GTHT12_RS06615 ed2d2453065cab0b85e849c227d9d33a 415 SUPERFAMILY SSF55021 260 346 9.92E-15 T 06-07-2017 GTHT12_RS06615 ed2d2453065cab0b85e849c227d9d33a 415 Gene3D G3DSA:3.40.1160.10 1 248 6.9E-66 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase GTHT12_RS06615 ed2d2453065cab0b85e849c227d9d33a 415 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 06-07-2017 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 GTHT12_RS06615 ed2d2453065cab0b85e849c227d9d33a 415 SUPERFAMILY SSF55021 335 403 7.79E-17 T 06-07-2017 GTHT12_RS06615 ed2d2453065cab0b85e849c227d9d33a 415 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 67 401 2.9E-95 T 06-07-2017 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 GTHT12_RS11385 2302a4d3fc5f494fcb06328ec30c4153 508 TIGRFAM TIGR01239 galT_2: galactose-1-phosphate uridylyltransferase 8 498 1.1E-198 T 06-07-2017 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 GTHT12_RS11385 2302a4d3fc5f494fcb06328ec30c4153 508 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 22 233 6.0E-40 T 06-07-2017 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 GTHT12_RS11385 2302a4d3fc5f494fcb06328ec30c4153 508 PIRSF PIRSF006005 2 503 3.0E-211 T 06-07-2017 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 GTHT12_RS11385 2302a4d3fc5f494fcb06328ec30c4153 508 Hamap MF_00571 Galactose-1-phosphate uridylyltransferase [galT]. 1 508 262.244 T 06-07-2017 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 GTHT12_RS11385 2302a4d3fc5f494fcb06328ec30c4153 508 ProSitePatterns PS01163 Galactose-1-phosphate uridyl transferase family 2 signature. 261 278 - T 06-07-2017 IPR023425 Galactose-1-phosphate uridyl transferase, class II, conserved site GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 GTHT12_RS11385 2302a4d3fc5f494fcb06328ec30c4153 508 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 248 428 2.0E-29 T 06-07-2017 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 GTHT12_RS04790 0326ddf356ad7c6c9413a662f2ae1e65 431 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 2.5E-9 T 06-07-2017 GTHT12_RS04790 0326ddf356ad7c6c9413a662f2ae1e65 431 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 310 2.5E-9 T 06-07-2017 GTHT12_RS04790 0326ddf356ad7c6c9413a662f2ae1e65 431 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 2.5E-9 T 06-07-2017 GTHT12_RS04790 0326ddf356ad7c6c9413a662f2ae1e65 431 Gene3D G3DSA:3.30.9.10 169 342 9.5E-21 T 06-07-2017 GTHT12_RS04790 0326ddf356ad7c6c9413a662f2ae1e65 431 SUPERFAMILY SSF51905 284 379 1.38E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS04790 0326ddf356ad7c6c9413a662f2ae1e65 431 SUPERFAMILY SSF51905 1 184 1.38E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS04790 0326ddf356ad7c6c9413a662f2ae1e65 431 Gene3D G3DSA:3.50.50.60 1 168 1.3E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS04790 0326ddf356ad7c6c9413a662f2ae1e65 431 SUPERFAMILY SSF54373 182 284 1.02E-18 T 06-07-2017 GTHT12_RS04790 0326ddf356ad7c6c9413a662f2ae1e65 431 Pfam PF12831 FAD dependent oxidoreductase 6 157 6.3E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS18185 cd3afdada91a75b45bee7c2eb6bca8c0 299 SUPERFAMILY SSF82861 28 118 6.41E-16 T 06-07-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 GTHT12_RS18185 cd3afdada91a75b45bee7c2eb6bca8c0 299 Gene3D G3DSA:3.30.70.100 190 272 5.5E-6 T 06-07-2017 GTHT12_RS18185 cd3afdada91a75b45bee7c2eb6bca8c0 299 Pfam PF00924 Mechanosensitive ion channel 77 273 1.1E-48 T 06-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 GTHT12_RS18185 cd3afdada91a75b45bee7c2eb6bca8c0 299 Gene3D G3DSA:2.30.30.60 135 182 5.0E-17 T 06-07-2017 GTHT12_RS18185 cd3afdada91a75b45bee7c2eb6bca8c0 299 SUPERFAMILY SSF82689 185 285 9.15E-16 T 06-07-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 GTHT12_RS18185 cd3afdada91a75b45bee7c2eb6bca8c0 299 SUPERFAMILY SSF50182 120 183 4.25E-17 T 06-07-2017 IPR010920 LSM domain GTHT12_RS10835 60a410e26bc0c036d8e0b032b2a2a0ef 257 Pfam PF01487 Type I 3-dehydroquinase 23 249 2.5E-65 T 06-07-2017 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 GTHT12_RS10835 60a410e26bc0c036d8e0b032b2a2a0ef 257 SUPERFAMILY SSF51569 6 253 1.22E-71 T 06-07-2017 GTHT12_RS10835 60a410e26bc0c036d8e0b032b2a2a0ef 257 Gene3D G3DSA:3.20.20.70 7 253 4.7E-80 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS10835 60a410e26bc0c036d8e0b032b2a2a0ef 257 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 21 252 31.463 T 06-07-2017 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 GTHT12_RS10835 60a410e26bc0c036d8e0b032b2a2a0ef 257 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 23 248 2.3E-62 T 06-07-2017 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 GTHT12_RS00955 41ad19184a939bac230480e8985b4d9c 331 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 21 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS00955 41ad19184a939bac230480e8985b4d9c 331 Gene3D G3DSA:1.10.240.10 208 299 1.4E-26 T 06-07-2017 GTHT12_RS00955 41ad19184a939bac230480e8985b4d9c 331 Pfam PF00579 tRNA synthetases class I (W and Y) 6 285 3.0E-60 T 06-07-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS00955 41ad19184a939bac230480e8985b4d9c 331 Gene3D G3DSA:3.40.50.620 4 207 2.9E-77 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS00955 41ad19184a939bac230480e8985b4d9c 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 2.8E-23 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 GTHT12_RS00955 41ad19184a939bac230480e8985b4d9c 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 194 204 2.8E-23 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 GTHT12_RS00955 41ad19184a939bac230480e8985b4d9c 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 143 164 2.8E-23 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 GTHT12_RS00955 41ad19184a939bac230480e8985b4d9c 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 66 85 2.8E-23 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 GTHT12_RS00955 41ad19184a939bac230480e8985b4d9c 331 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 4 328 2.0E-91 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 GTHT12_RS00955 41ad19184a939bac230480e8985b4d9c 331 SUPERFAMILY SSF52374 6 328 2.37E-81 T 06-07-2017 GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 Gene3D G3DSA:1.10.8.60 538 609 1.1E-22 T 06-07-2017 GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 SMART SM00382 384 528 3.7E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 Gene3D G3DSA:3.30.450.20 126 224 1.1E-15 T 06-07-2017 GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 Gene3D G3DSA:3.30.450.20 242 325 3.3E-4 T 06-07-2017 GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 Pfam PF00571 CBS domain 5 57 0.0043 T 06-07-2017 IPR000644 CBS domain GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 Pfam PF00571 CBS domain 75 115 6.1E-4 T 06-07-2017 IPR000644 CBS domain GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 451 466 - T 06-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 Gene3D G3DSA:3.40.50.300 361 537 5.0E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 Gene3D G3DSA:1.10.10.60 624 674 2.9E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 SMART SM00091 241 306 42.0 T 06-07-2017 IPR000014 PAS domain GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 SMART SM00091 125 192 1.8E-8 T 06-07-2017 IPR000014 PAS domain GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 388 401 - T 06-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 SUPERFAMILY SSF46689 620 674 9.99E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 SUPERFAMILY SSF54631 3 119 5.61E-18 T 06-07-2017 GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 577 586 - T 06-07-2017 IPR025944 Sigma-54 interaction domain, conserved site GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 SUPERFAMILY SSF55785 126 220 2.09E-15 T 06-07-2017 IPR000014 PAS domain GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 SUPERFAMILY SSF52540 364 607 1.82E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 Pfam PF00989 PAS fold 126 223 5.5E-10 T 06-07-2017 IPR013767 PAS fold GO:0006355 GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 Gene3D G3DSA:3.10.580.10 2 118 7.2E-17 T 06-07-2017 GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 Pfam PF13188 PAS domain 243 274 0.004 T 06-07-2017 IPR000014 PAS domain GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 Pfam PF00158 Sigma-54 interaction domain 365 531 1.1E-66 T 06-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 Pfam PF02954 Bacterial regulatory protein, Fis family 632 671 1.3E-6 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 124 227 4.2E-10 T 06-07-2017 IPR000014 PAS domain GTHT12_RS01175 20a47e5716b80235bfb449f2e2bc0cd0 689 SUPERFAMILY SSF55785 234 331 7.12E-6 T 06-07-2017 IPR000014 PAS domain GTHT12_RS03545 c4c12e2ab7ffecfba337346c82c607a3 295 Pfam PF13556 PucR C-terminal helix-turn-helix domain 236 289 6.5E-17 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain GTHT12_RS03545 c4c12e2ab7ffecfba337346c82c607a3 295 Gene3D G3DSA:1.10.10.60 238 268 7.8E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS03545 c4c12e2ab7ffecfba337346c82c607a3 295 SUPERFAMILY SSF46689 227 268 4.12E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS17820 983457f59787a9b28559d95d3c53f44a 162 Pfam PF13581 Histidine kinase-like ATPase domain 12 139 5.6E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS17820 983457f59787a9b28559d95d3c53f44a 162 TIGRFAM TIGR01924 rsbW_low_gc: anti-sigma B factor 1 149 9.1E-47 T 06-07-2017 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 GTHT12_RS17820 983457f59787a9b28559d95d3c53f44a 162 SUPERFAMILY SSF55874 33 137 1.07E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS17820 983457f59787a9b28559d95d3c53f44a 162 Gene3D G3DSA:3.30.565.10 17 139 4.8E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS13330 927ae482fe50bb5fdf466d13ba6eff35 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 51 - T 06-07-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 GTHT12_RS13330 927ae482fe50bb5fdf466d13ba6eff35 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 85 158 9.1E-29 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 GTHT12_RS13330 927ae482fe50bb5fdf466d13ba6eff35 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 158 1.7E-59 T 06-07-2017 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 GTHT12_RS13330 927ae482fe50bb5fdf466d13ba6eff35 158 SUPERFAMILY SSF46557 5 79 1.57E-27 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 GTHT12_RS13330 927ae482fe50bb5fdf466d13ba6eff35 158 Gene3D G3DSA:3.10.50.30 79 158 9.3E-32 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 GTHT12_RS13330 927ae482fe50bb5fdf466d13ba6eff35 158 Pfam PF03449 Transcription elongation factor, N-terminal 8 77 1.9E-32 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 GTHT12_RS13330 927ae482fe50bb5fdf466d13ba6eff35 158 Gene3D G3DSA:1.10.287.180 5 78 3.6E-33 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 GTHT12_RS13330 927ae482fe50bb5fdf466d13ba6eff35 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 123 139 - T 06-07-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 GTHT12_RS13330 927ae482fe50bb5fdf466d13ba6eff35 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 158 33.397 T 06-07-2017 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 GTHT12_RS13330 927ae482fe50bb5fdf466d13ba6eff35 158 SUPERFAMILY SSF54534 84 157 6.67E-23 T 06-07-2017 GTHT12_RS13330 927ae482fe50bb5fdf466d13ba6eff35 158 PIRSF PIRSF006092 1 158 1.0E-55 T 06-07-2017 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 GTHT12_RS12110 b71ba34b8af00b226cf9c0ddd6a209fe 214 SUPERFAMILY SSF63380 92 194 3.32E-32 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 GTHT12_RS12110 b71ba34b8af00b226cf9c0ddd6a209fe 214 Gene3D G3DSA:2.40.30.20 5 103 2.0E-36 T 06-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 GTHT12_RS12110 b71ba34b8af00b226cf9c0ddd6a209fe 214 SUPERFAMILY SSF63380 1 88 1.7E-28 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 GTHT12_RS12110 b71ba34b8af00b226cf9c0ddd6a209fe 214 Pfam PF00677 Lumazine binding domain 3 86 6.3E-25 T 06-07-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GTHT12_RS12110 b71ba34b8af00b226cf9c0ddd6a209fe 214 Pfam PF00677 Lumazine binding domain 99 183 7.4E-21 T 06-07-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GTHT12_RS12110 b71ba34b8af00b226cf9c0ddd6a209fe 214 Gene3D G3DSA:2.40.30.20 104 193 3.8E-28 T 06-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 GTHT12_RS12110 b71ba34b8af00b226cf9c0ddd6a209fe 214 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 194 3.7E-78 T 06-07-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GTHT12_RS12110 b71ba34b8af00b226cf9c0ddd6a209fe 214 PIRSF PIRSF000498 1 208 1.7E-77 T 06-07-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GTHT12_RS13690 d153e86124714d35224e0945bb45b71c 143 Gene3D G3DSA:3.30.700.10 9 45 1.4E-4 T 06-07-2017 GTHT12_RS13690 d153e86124714d35224e0945bb45b71c 143 Pfam PF13633 Prokaryotic N-terminal methylation site 5 26 1.2E-7 T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site GTHT12_RS13690 d153e86124714d35224e0945bb45b71c 143 SUPERFAMILY SSF54523 8 53 1.02E-7 T 06-07-2017 GTHT12_RS13690 d153e86124714d35224e0945bb45b71c 143 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 26 1.1E-8 T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site GTHT12_RS13690 d153e86124714d35224e0945bb45b71c 143 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site GTHT12_RS12400 7e5c2ddc891b81dab5d11e7394e65cd2 682 SUPERFAMILY SSF52242 515 675 5.65E-34 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 GTHT12_RS12400 7e5c2ddc891b81dab5d11e7394e65cd2 682 SUPERFAMILY SSF51703 10 511 1.2E-152 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 GTHT12_RS12400 7e5c2ddc891b81dab5d11e7394e65cd2 682 Gene3D G3DSA:3.40.50.280 539 675 1.7E-34 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 GTHT12_RS12400 7e5c2ddc891b81dab5d11e7394e65cd2 682 Pfam PF01642 Methylmalonyl-CoA mutase 40 577 7.5E-147 T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 GTHT12_RS12400 7e5c2ddc891b81dab5d11e7394e65cd2 682 Gene3D G3DSA:3.20.20.240 39 477 3.1E-153 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 GTHT12_RS05415 27345d715e4b89d6287db15f000aeaaa 402 SUPERFAMILY SSF47203 245 401 3.87E-47 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS05415 27345d715e4b89d6287db15f000aeaaa 402 Gene3D G3DSA:1.10.540.10 1 132 1.2E-38 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS05415 27345d715e4b89d6287db15f000aeaaa 402 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 134 229 1.6E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 GTHT12_RS05415 27345d715e4b89d6287db15f000aeaaa 402 Gene3D G3DSA:2.40.110.10 133 236 7.0E-40 T 06-07-2017 GTHT12_RS05415 27345d715e4b89d6287db15f000aeaaa 402 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 247 395 4.7E-38 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS05415 27345d715e4b89d6287db15f000aeaaa 402 Gene3D G3DSA:1.20.140.10 237 401 1.3E-49 T 06-07-2017 GTHT12_RS05415 27345d715e4b89d6287db15f000aeaaa 402 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 130 1.2E-16 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS05415 27345d715e4b89d6287db15f000aeaaa 402 SUPERFAMILY SSF56645 1 260 3.14E-71 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 GTHT12_RS03525 23b3dacc86057cfe43f4ee6da324f628 423 SMART SM00116 273 321 5.9 T 06-07-2017 IPR000644 CBS domain GTHT12_RS03525 23b3dacc86057cfe43f4ee6da324f628 423 SMART SM00116 211 260 0.048 T 06-07-2017 IPR000644 CBS domain GTHT12_RS03525 23b3dacc86057cfe43f4ee6da324f628 423 Gene3D G3DSA:3.10.580.10 188 328 9.9E-21 T 06-07-2017 GTHT12_RS03525 23b3dacc86057cfe43f4ee6da324f628 423 SUPERFAMILY SSF54631 197 339 3.03E-34 T 06-07-2017 GTHT12_RS03525 23b3dacc86057cfe43f4ee6da324f628 423 Pfam PF03471 Transporter associated domain 337 413 1.6E-21 T 06-07-2017 IPR005170 Transporter-associated domain GTHT12_RS03525 23b3dacc86057cfe43f4ee6da324f628 423 SUPERFAMILY SSF56176 335 415 5.45E-21 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 GTHT12_RS03525 23b3dacc86057cfe43f4ee6da324f628 423 SMART SM01091 336 414 3.2E-27 T 06-07-2017 IPR005170 Transporter-associated domain GTHT12_RS03525 23b3dacc86057cfe43f4ee6da324f628 423 Pfam PF00571 CBS domain 271 321 2.5E-5 T 06-07-2017 IPR000644 CBS domain GTHT12_RS03525 23b3dacc86057cfe43f4ee6da324f628 423 Pfam PF00571 CBS domain 202 259 1.8E-7 T 06-07-2017 IPR000644 CBS domain GTHT12_RS03525 23b3dacc86057cfe43f4ee6da324f628 423 Gene3D G3DSA:3.30.465.10 329 412 4.0E-24 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 GTHT12_RS03525 23b3dacc86057cfe43f4ee6da324f628 423 Pfam PF01595 Domain of unknown function DUF21 12 187 2.1E-40 T 06-07-2017 IPR002550 Domain of unknown function DUF21 GTHT12_RS06140 e78e08a6781230630f979dc367228f6a 61 Pfam PF00830 Ribosomal L28 family 3 57 8.5E-21 T 06-07-2017 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS06140 e78e08a6781230630f979dc367228f6a 61 Gene3D G3DSA:4.10.1160.10 18 60 5.5E-22 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS06140 e78e08a6781230630f979dc367228f6a 61 SUPERFAMILY SSF143800 1 60 2.55E-22 T 06-07-2017 GTHT12_RS06140 e78e08a6781230630f979dc367228f6a 61 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 61 17.988 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS06140 e78e08a6781230630f979dc367228f6a 61 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 55 6.6E-22 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS02295 36cb90388b795ebe77b2094956a6e088 142 Gene3D G3DSA:1.10.1660.10 4 134 3.3E-33 T 06-07-2017 GTHT12_RS02295 36cb90388b795ebe77b2094956a6e088 142 SMART SM00422 4 74 3.0E-31 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS02295 36cb90388b795ebe77b2094956a6e088 142 SUPERFAMILY SSF46955 4 116 1.21E-24 T 06-07-2017 IPR009061 Putative DNA-binding domain GTHT12_RS02295 36cb90388b795ebe77b2094956a6e088 142 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 8.8E-5 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS02295 36cb90388b795ebe77b2094956a6e088 142 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 8.8E-5 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS02295 36cb90388b795ebe77b2094956a6e088 142 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 40 60 8.8E-5 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS02295 36cb90388b795ebe77b2094956a6e088 142 Pfam PF13411 MerR HTH family regulatory protein 5 71 5.5E-20 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS06835 330b67ba8418ae8de487559da25cf4bb 382 Gene3D G3DSA:3.40.47.10 4 124 3.3E-72 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS06835 330b67ba8418ae8de487559da25cf4bb 382 Gene3D G3DSA:3.40.47.10 183 265 3.3E-72 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS06835 330b67ba8418ae8de487559da25cf4bb 382 ProSitePatterns PS00099 Thiolases active site. 363 376 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 GTHT12_RS06835 330b67ba8418ae8de487559da25cf4bb 382 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 380 5.4E-143 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 GTHT12_RS06835 330b67ba8418ae8de487559da25cf4bb 382 SUPERFAMILY SSF53901 260 381 2.27E-43 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS06835 330b67ba8418ae8de487559da25cf4bb 382 Pfam PF00108 Thiolase, N-terminal domain 5 251 3.7E-80 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 GTHT12_RS06835 330b67ba8418ae8de487559da25cf4bb 382 Pfam PF02803 Thiolase, C-terminal domain 259 381 1.5E-44 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 GTHT12_RS06835 330b67ba8418ae8de487559da25cf4bb 382 Gene3D G3DSA:3.40.47.10 266 381 3.9E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS06835 330b67ba8418ae8de487559da25cf4bb 382 Gene3D G3DSA:3.40.47.10 136 182 3.9E-60 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS06835 330b67ba8418ae8de487559da25cf4bb 382 SUPERFAMILY SSF53901 1 256 3.26E-82 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS06835 330b67ba8418ae8de487559da25cf4bb 382 PIRSF PIRSF000429 1 382 2.8E-136 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 GTHT12_RS06835 330b67ba8418ae8de487559da25cf4bb 382 ProSitePatterns PS00737 Thiolases signature 2. 328 344 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 GTHT12_RS12970 6b45b49fa39a62ac81f97fef5c87dbab 299 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 175 182 - T 06-07-2017 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 GTHT12_RS12970 6b45b49fa39a62ac81f97fef5c87dbab 299 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 213 229 - T 06-07-2017 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 GTHT12_RS12970 6b45b49fa39a62ac81f97fef5c87dbab 299 Pfam PF01261 Xylose isomerase-like TIM barrel 22 237 2.7E-36 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain GTHT12_RS12970 6b45b49fa39a62ac81f97fef5c87dbab 299 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 3 282 6.5E-103 T 06-07-2017 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 GTHT12_RS12970 6b45b49fa39a62ac81f97fef5c87dbab 299 SMART SM00518 3 285 1.7E-130 T 06-07-2017 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 GTHT12_RS12970 6b45b49fa39a62ac81f97fef5c87dbab 299 SUPERFAMILY SSF51658 2 294 2.36E-103 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain GTHT12_RS12970 6b45b49fa39a62ac81f97fef5c87dbab 299 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 69 77 - T 06-07-2017 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 GTHT12_RS12970 6b45b49fa39a62ac81f97fef5c87dbab 299 Gene3D G3DSA:3.20.20.150 1 283 4.9E-107 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain GTHT12_RS12970 6b45b49fa39a62ac81f97fef5c87dbab 299 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 285 43.388 T 06-07-2017 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 GTHT12_RS08390 3f0be9b637e624381f0de883905c56e7 215 Gene3D G3DSA:2.40.33.20 1 213 2.5E-76 T 06-07-2017 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like GTHT12_RS08390 3f0be9b637e624381f0de883905c56e7 215 Pfam PF03473 MOSC domain 50 156 2.1E-16 T 06-07-2017 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 GTHT12_RS08390 3f0be9b637e624381f0de883905c56e7 215 Pfam PF03475 3-alpha domain 170 211 3.4E-13 T 06-07-2017 IPR005163 3-alpha domain GTHT12_RS08390 3f0be9b637e624381f0de883905c56e7 215 SUPERFAMILY SSF50800 1 212 7.85E-67 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain GTHT12_RS04835 654bd9bac89668e8e43fd5057af802b0 760 SUPERFAMILY SSF48168 13 230 1.96E-57 T 06-07-2017 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GTHT12_RS04835 654bd9bac89668e8e43fd5057af802b0 760 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 155 747 5.8E-183 T 06-07-2017 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GTHT12_RS04835 654bd9bac89668e8e43fd5057af802b0 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 499 522 3.0E-40 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GTHT12_RS04835 654bd9bac89668e8e43fd5057af802b0 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 448 459 3.0E-40 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GTHT12_RS04835 654bd9bac89668e8e43fd5057af802b0 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 307 326 3.0E-40 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GTHT12_RS04835 654bd9bac89668e8e43fd5057af802b0 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 537 559 3.0E-40 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GTHT12_RS04835 654bd9bac89668e8e43fd5057af802b0 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 629 656 3.0E-40 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GTHT12_RS04835 654bd9bac89668e8e43fd5057af802b0 760 PRINTS PR01183 Ribonucleotide reductase large chain signature 565 588 3.0E-40 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GTHT12_RS04835 654bd9bac89668e8e43fd5057af802b0 760 Gene3D G3DSA:3.20.70.20 414 585 1.7E-69 T 06-07-2017 GTHT12_RS04835 654bd9bac89668e8e43fd5057af802b0 760 Gene3D G3DSA:3.20.70.20 147 353 1.7E-69 T 06-07-2017 GTHT12_RS04835 654bd9bac89668e8e43fd5057af802b0 760 Gene3D G3DSA:3.20.70.20 629 746 1.7E-69 T 06-07-2017 GTHT12_RS04835 654bd9bac89668e8e43fd5057af802b0 760 Pfam PF02867 Ribonucleotide reductase, barrel domain 232 744 2.1E-153 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GTHT12_RS04835 654bd9bac89668e8e43fd5057af802b0 760 SUPERFAMILY SSF51998 231 758 1.56E-175 T 06-07-2017 GTHT12_RS04835 654bd9bac89668e8e43fd5057af802b0 760 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 618 640 - T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GTHT12_RS04835 654bd9bac89668e8e43fd5057af802b0 760 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 152 228 2.0E-19 T 06-07-2017 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GTHT12_RS03955 960b95fbc07cd3cfc13218c4be1c5d0b 1136 Gene3D G3DSA:3.20.20.20 345 594 8.2E-94 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GTHT12_RS03955 960b95fbc07cd3cfc13218c4be1c5d0b 1136 SUPERFAMILY SSF82282 5 379 4.84E-116 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 GTHT12_RS03955 960b95fbc07cd3cfc13218c4be1c5d0b 1136 SUPERFAMILY SSF47644 622 706 7.72E-25 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GTHT12_RS03955 960b95fbc07cd3cfc13218c4be1c5d0b 1136 Pfam PF00809 Pterin binding enzyme 340 573 2.5E-42 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GTHT12_RS03955 960b95fbc07cd3cfc13218c4be1c5d0b 1136 TIGRFAM TIGR02082 metH: methionine synthase 10 1135 0.0 T 06-07-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GTHT12_RS03955 960b95fbc07cd3cfc13218c4be1c5d0b 1136 Pfam PF02607 B12 binding domain 627 700 2.2E-23 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GTHT12_RS03955 960b95fbc07cd3cfc13218c4be1c5d0b 1136 Pfam PF02310 B12 binding domain 713 829 5.9E-22 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 GTHT12_RS03955 960b95fbc07cd3cfc13218c4be1c5d0b 1136 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 888 1135 9.6E-62 T 06-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GTHT12_RS03955 960b95fbc07cd3cfc13218c4be1c5d0b 1136 SMART SM01018 624 707 4.9E-39 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GTHT12_RS03955 960b95fbc07cd3cfc13218c4be1c5d0b 1136 Gene3D G3DSA:3.20.20.330 4 344 4.7E-117 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 GTHT12_RS03955 960b95fbc07cd3cfc13218c4be1c5d0b 1136 Pfam PF02574 Homocysteine S-methyltransferase 15 305 1.2E-82 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 GTHT12_RS03955 960b95fbc07cd3cfc13218c4be1c5d0b 1136 SUPERFAMILY SSF51717 337 600 3.79E-81 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GTHT12_RS03955 960b95fbc07cd3cfc13218c4be1c5d0b 1136 PIRSF PIRSF000381 1 1136 0.0 T 06-07-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GTHT12_RS03955 960b95fbc07cd3cfc13218c4be1c5d0b 1136 Gene3D G3DSA:3.40.50.280 710 844 8.1E-51 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 GTHT12_RS03955 960b95fbc07cd3cfc13218c4be1c5d0b 1136 SUPERFAMILY SSF52242 708 836 6.41E-40 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 GTHT12_RS03955 960b95fbc07cd3cfc13218c4be1c5d0b 1136 SUPERFAMILY SSF56507 859 1135 6.8E-96 T 06-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GTHT12_RS03955 960b95fbc07cd3cfc13218c4be1c5d0b 1136 Gene3D G3DSA:1.10.1240.10 623 704 4.0E-29 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GTHT12_RS03955 960b95fbc07cd3cfc13218c4be1c5d0b 1136 Gene3D G3DSA:3.10.196.10 916 1135 7.6E-71 T 06-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GTHT12_RS00765 71e2a06cc8029d53a55a526e7d42e010 217 Hamap MF_00235 Adenylate kinase [adk]. 1 213 54.074 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 GTHT12_RS00765 71e2a06cc8029d53a55a526e7d42e010 217 PRINTS PR00094 Adenylate kinase signature 160 175 4.5E-33 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 GTHT12_RS00765 71e2a06cc8029d53a55a526e7d42e010 217 PRINTS PR00094 Adenylate kinase signature 177 191 4.5E-33 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 GTHT12_RS00765 71e2a06cc8029d53a55a526e7d42e010 217 PRINTS PR00094 Adenylate kinase signature 32 46 4.5E-33 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 GTHT12_RS00765 71e2a06cc8029d53a55a526e7d42e010 217 PRINTS PR00094 Adenylate kinase signature 4 17 4.5E-33 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 GTHT12_RS00765 71e2a06cc8029d53a55a526e7d42e010 217 PRINTS PR00094 Adenylate kinase signature 81 97 4.5E-33 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 GTHT12_RS00765 71e2a06cc8029d53a55a526e7d42e010 217 SUPERFAMILY SSF52540 1 214 3.79E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00765 71e2a06cc8029d53a55a526e7d42e010 217 Gene3D G3DSA:3.40.50.300 1 211 3.5E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00765 71e2a06cc8029d53a55a526e7d42e010 217 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 1.4E-81 T 06-07-2017 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 GTHT12_RS00765 71e2a06cc8029d53a55a526e7d42e010 217 Pfam PF00406 Adenylate kinase 5 190 3.2E-62 T 06-07-2017 GTHT12_RS00765 71e2a06cc8029d53a55a526e7d42e010 217 Pfam PF05191 Adenylate kinase, active site lid 127 162 1.2E-17 T 06-07-2017 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 GTHT12_RS00765 71e2a06cc8029d53a55a526e7d42e010 217 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 06-07-2017 GTHT12_RS06435 461d5d66be82d2444bbdc2bbc130833f 287 PIRSF PIRSF003092 2 287 1.2E-78 T 06-07-2017 IPR025501 ATP binding protein MinD GTHT12_RS06435 461d5d66be82d2444bbdc2bbc130833f 287 Gene3D G3DSA:3.40.50.300 22 260 8.9E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06435 461d5d66be82d2444bbdc2bbc130833f 287 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 25 233 4.8E-23 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain GTHT12_RS06435 461d5d66be82d2444bbdc2bbc130833f 287 SUPERFAMILY SSF52540 22 267 1.04E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17225 7d4d6a8f5d868c3ff60897c6040eebfb 462 Gene3D G3DSA:2.60.120.10 333 440 3.9E-23 T 06-07-2017 IPR014710 RmlC-like jelly roll fold GTHT12_RS17225 7d4d6a8f5d868c3ff60897c6040eebfb 462 SUPERFAMILY SSF51182 192 451 8.23E-35 T 06-07-2017 IPR011051 RmlC-like cupin domain GTHT12_RS17225 7d4d6a8f5d868c3ff60897c6040eebfb 462 Gene3D G3DSA:3.90.550.10 1 257 1.5E-54 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS17225 7d4d6a8f5d868c3ff60897c6040eebfb 462 SUPERFAMILY SSF53448 1 265 4.78E-48 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS17225 7d4d6a8f5d868c3ff60897c6040eebfb 462 Pfam PF00483 Nucleotidyl transferase 4 269 4.0E-34 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 GTHT12_RS17225 7d4d6a8f5d868c3ff60897c6040eebfb 462 Pfam PF01050 Mannose-6-phosphate isomerase 298 442 2.5E-16 T 06-07-2017 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 GTHT12_RS14600 27d996346902a3462dda6e22b857c20d 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 8.1E-22 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS14600 27d996346902a3462dda6e22b857c20d 331 SUPERFAMILY SSF53822 62 331 5.8E-92 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS14600 27d996346902a3462dda6e22b857c20d 331 Gene3D G3DSA:3.40.50.2300 174 311 3.3E-52 T 06-07-2017 GTHT12_RS14600 27d996346902a3462dda6e22b857c20d 331 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 06-07-2017 GTHT12_RS14600 27d996346902a3462dda6e22b857c20d 331 TIGRFAM TIGR01481 ccpA: catabolite control protein A 1 331 1.6E-160 T 06-07-2017 IPR006377 Catabolite control protein A GO:0006355 GTHT12_RS14600 27d996346902a3462dda6e22b857c20d 331 SUPERFAMILY SSF47413 2 60 5.3E-20 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS14600 27d996346902a3462dda6e22b857c20d 331 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 4.3E-6 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS14600 27d996346902a3462dda6e22b857c20d 331 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 4.3E-6 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS14600 27d996346902a3462dda6e22b857c20d 331 SMART SM00354 2 72 8.8E-40 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS14600 27d996346902a3462dda6e22b857c20d 331 Pfam PF13377 Periplasmic binding protein-like domain 169 330 1.6E-38 T 06-07-2017 GTHT12_RS14600 27d996346902a3462dda6e22b857c20d 331 Gene3D G3DSA:1.10.260.40 3 54 2.7E-28 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS14600 27d996346902a3462dda6e22b857c20d 331 Gene3D G3DSA:3.40.50.2300 55 173 5.7E-53 T 06-07-2017 GTHT12_RS12390 05cf0871d58ceea7d31d54943cc5f111 381 Gene3D G3DSA:3.40.50.300 103 306 4.4E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12390 05cf0871d58ceea7d31d54943cc5f111 381 Gene3D G3DSA:1.20.5.170 45 102 1.6E-24 T 06-07-2017 GTHT12_RS12390 05cf0871d58ceea7d31d54943cc5f111 381 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 65 348 1.2E-101 T 06-07-2017 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 GTHT12_RS12390 05cf0871d58ceea7d31d54943cc5f111 381 Pfam PF03308 ArgK protein 70 340 1.0E-104 T 06-07-2017 GTHT12_RS12390 05cf0871d58ceea7d31d54943cc5f111 381 SUPERFAMILY SSF52540 54 373 3.87E-93 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS14125 a0d3776c08a6cb74d88c824119521074 361 PIRSF PIRSF001123 4 361 2.3E-153 T 06-07-2017 IPR008007 Peptidase M42 GTHT12_RS14125 a0d3776c08a6cb74d88c824119521074 361 Pfam PF05343 M42 glutamyl aminopeptidase 48 342 4.8E-121 T 06-07-2017 IPR008007 Peptidase M42 GTHT12_RS14125 a0d3776c08a6cb74d88c824119521074 361 Gene3D G3DSA:2.40.30.40 78 163 2.7E-40 T 06-07-2017 IPR023367 Peptidase M42, domain 2 GTHT12_RS14125 a0d3776c08a6cb74d88c824119521074 361 Gene3D G3DSA:3.40.630.10 174 359 1.6E-91 T 06-07-2017 GTHT12_RS14125 a0d3776c08a6cb74d88c824119521074 361 Gene3D G3DSA:3.40.630.10 2 77 1.6E-91 T 06-07-2017 GTHT12_RS14125 a0d3776c08a6cb74d88c824119521074 361 SUPERFAMILY SSF53187 6 83 1.21E-75 T 06-07-2017 GTHT12_RS14125 a0d3776c08a6cb74d88c824119521074 361 SUPERFAMILY SSF53187 174 357 1.21E-75 T 06-07-2017 GTHT12_RS14125 a0d3776c08a6cb74d88c824119521074 361 SUPERFAMILY SSF101821 73 182 4.12E-35 T 06-07-2017 GTHT12_RS18110 44110ab0b8a3d65e0c84222b55bb5c28 260 Pfam PF09648 YycH protein 39 247 4.1E-63 T 06-07-2017 IPR018604 Regulatory protein YycH-like GO:0016021 GTHT12_RS10330 f2752845876e22e1e090449123620d8b 454 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 79 404 3.5E-52 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GTHT12_RS10330 f2752845876e22e1e090449123620d8b 454 SUPERFAMILY SSF53686 56 445 3.84E-58 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GTHT12_RS10330 f2752845876e22e1e090449123620d8b 454 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 113 127 - T 06-07-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 GTHT12_RS10330 f2752845876e22e1e090449123620d8b 454 Gene3D G3DSA:3.40.50.1100 185 445 6.5E-43 T 06-07-2017 GTHT12_RS10330 f2752845876e22e1e090449123620d8b 454 TIGRFAM TIGR02035 D_Ser_am_lyase: D-serine ammonia-lyase 15 444 9.5E-214 T 06-07-2017 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 GTHT12_RS10330 f2752845876e22e1e090449123620d8b 454 Hamap MF_01030 D-serine dehydratase [dsdA]. 1 454 256.647 T 06-07-2017 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 GTHT12_RS10920 d951a3095785704dde63379a29fd98fa 92 Pfam PF03625 Domain of unknown function DUF302 5 61 7.0E-17 T 06-07-2017 IPR005180 Domain of unknown function DUF302 GTHT12_RS10920 d951a3095785704dde63379a29fd98fa 92 SUPERFAMILY SSF103247 2 90 7.59E-23 T 06-07-2017 IPR005180 Domain of unknown function DUF302 GTHT12_RS10920 d951a3095785704dde63379a29fd98fa 92 PIRSF PIRSF021774 1 92 2.7E-28 T 06-07-2017 IPR016796 Uncharacterised conserved protein UCP021774 GTHT12_RS10920 d951a3095785704dde63379a29fd98fa 92 Gene3D G3DSA:3.30.310.70 2 90 5.4E-25 T 06-07-2017 IPR005180 Domain of unknown function DUF302 GTHT12_RS06500 c5bf549a18487f7c6c3a09c0ecddf7b1 257 SUPERFAMILY SSF64005 23 248 2.88E-90 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 GTHT12_RS06500 c5bf549a18487f7c6c3a09c0ecddf7b1 257 Pfam PF01255 Putative undecaprenyl diphosphate synthase 32 252 1.6E-83 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 GTHT12_RS06500 c5bf549a18487f7c6c3a09c0ecddf7b1 257 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 25 252 1.3E-86 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 GTHT12_RS06500 c5bf549a18487f7c6c3a09c0ecddf7b1 257 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 198 215 - T 06-07-2017 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 GTHT12_RS06500 c5bf549a18487f7c6c3a09c0ecddf7b1 257 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 25 253 40.601 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 GTHT12_RS06500 c5bf549a18487f7c6c3a09c0ecddf7b1 257 Gene3D G3DSA:3.40.1180.10 18 255 2.6E-102 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 GTHT12_RS18225 b2b14e60173ba90135149129c6f82e49 462 Pfam PF01926 50S ribosome-binding GTPase 228 339 1.5E-25 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS18225 b2b14e60173ba90135149129c6f82e49 462 Gene3D G3DSA:3.40.50.300 294 396 3.4E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18225 b2b14e60173ba90135149129c6f82e49 462 SUPERFAMILY SSF52540 81 170 1.01E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18225 b2b14e60173ba90135149129c6f82e49 462 SUPERFAMILY SSF52540 205 379 1.01E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18225 b2b14e60173ba90135149129c6f82e49 462 Pfam PF10396 GTP-binding protein TrmE N-terminus 6 127 5.0E-41 T 06-07-2017 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 GTHT12_RS18225 b2b14e60173ba90135149129c6f82e49 462 Gene3D G3DSA:3.40.50.300 225 255 8.0E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18225 b2b14e60173ba90135149129c6f82e49 462 Pfam PF12631 MnmE helical domain 130 459 5.3E-60 T 06-07-2017 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 GTHT12_RS18225 b2b14e60173ba90135149129c6f82e49 462 PRINTS PR00449 Transforming protein P21 ras signature 265 287 2.5E-5 T 06-07-2017 GTHT12_RS18225 b2b14e60173ba90135149129c6f82e49 462 PRINTS PR00449 Transforming protein P21 ras signature 329 342 2.5E-5 T 06-07-2017 GTHT12_RS18225 b2b14e60173ba90135149129c6f82e49 462 PRINTS PR00449 Transforming protein P21 ras signature 225 246 2.5E-5 T 06-07-2017 GTHT12_RS18225 b2b14e60173ba90135149129c6f82e49 462 Gene3D G3DSA:3.30.1360.120 1 128 7.0E-47 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 GTHT12_RS18225 b2b14e60173ba90135149129c6f82e49 462 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 5 462 34.973 T 06-07-2017 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 GTHT12_RS18225 b2b14e60173ba90135149129c6f82e49 462 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 12 462 2.0E-135 T 06-07-2017 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 GTHT12_RS18225 b2b14e60173ba90135149129c6f82e49 462 SUPERFAMILY SSF116878 387 462 4.71E-51 T 06-07-2017 GTHT12_RS18225 b2b14e60173ba90135149129c6f82e49 462 SUPERFAMILY SSF116878 128 228 4.71E-51 T 06-07-2017 GTHT12_RS18225 b2b14e60173ba90135149129c6f82e49 462 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 228 376 7.6E-28 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 GTHT12_RS18225 b2b14e60173ba90135149129c6f82e49 462 Gene3D G3DSA:1.20.120.430 129 189 4.2E-56 T 06-07-2017 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 GTHT12_RS18225 b2b14e60173ba90135149129c6f82e49 462 Gene3D G3DSA:1.20.120.430 397 462 4.2E-56 T 06-07-2017 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 GTHT12_RS18225 b2b14e60173ba90135149129c6f82e49 462 Gene3D G3DSA:1.20.120.430 256 279 4.2E-56 T 06-07-2017 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 GTHT12_RS04680 5982d8bfcc021dded802dc36bb347276 425 Pfam PF01548 Transposase 19 179 4.6E-37 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 GTHT12_RS04680 5982d8bfcc021dded802dc36bb347276 425 Pfam PF02371 Transposase IS116/IS110/IS902 family 287 371 2.5E-23 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 GTHT12_RS02130 5982d8bfcc021dded802dc36bb347276 425 Pfam PF01548 Transposase 19 179 4.6E-37 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 GTHT12_RS02130 5982d8bfcc021dded802dc36bb347276 425 Pfam PF02371 Transposase IS116/IS110/IS902 family 287 371 2.5E-23 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 GTHT12_RS11265 5982d8bfcc021dded802dc36bb347276 425 Pfam PF01548 Transposase 19 179 4.6E-37 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 GTHT12_RS11265 5982d8bfcc021dded802dc36bb347276 425 Pfam PF02371 Transposase IS116/IS110/IS902 family 287 371 2.5E-23 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 GTHT12_RS03310 5982d8bfcc021dded802dc36bb347276 425 Pfam PF01548 Transposase 19 179 4.6E-37 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 GTHT12_RS03310 5982d8bfcc021dded802dc36bb347276 425 Pfam PF02371 Transposase IS116/IS110/IS902 family 287 371 2.5E-23 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 GTHT12_RS10250 5982d8bfcc021dded802dc36bb347276 425 Pfam PF01548 Transposase 19 179 4.6E-37 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 GTHT12_RS10250 5982d8bfcc021dded802dc36bb347276 425 Pfam PF02371 Transposase IS116/IS110/IS902 family 287 371 2.5E-23 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 GTHT12_RS18895 2196d9fb6d3e5e4f3a4fa4a1b3743eab 81 SMART SM00530 12 67 4.2E-18 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GTHT12_RS18895 2196d9fb6d3e5e4f3a4fa4a1b3743eab 81 Pfam PF01381 Helix-turn-helix 13 67 4.7E-19 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GTHT12_RS18895 2196d9fb6d3e5e4f3a4fa4a1b3743eab 81 SUPERFAMILY SSF47413 3 70 1.49E-21 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS18895 2196d9fb6d3e5e4f3a4fa4a1b3743eab 81 Gene3D G3DSA:1.10.260.40 4 77 3.5E-24 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS15065 f7be3881e2dd9c8cdfab40a1c91e26d2 131 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 4 95 1.5E-6 T 06-07-2017 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 GTHT12_RS15065 f7be3881e2dd9c8cdfab40a1c91e26d2 131 Gene3D G3DSA:3.40.50.1810 1 92 7.1E-6 T 06-07-2017 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 GTHT12_RS15065 f7be3881e2dd9c8cdfab40a1c91e26d2 131 SUPERFAMILY SSF52309 1 93 9.46E-9 T 06-07-2017 GTHT12_RS12000 5b03bc4f41c090e9a8d71286bdfd1ae1 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 2.6E-22 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS12000 5b03bc4f41c090e9a8d71286bdfd1ae1 242 Pfam PF07702 UTRA domain 94 233 8.8E-45 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 GTHT12_RS12000 5b03bc4f41c090e9a8d71286bdfd1ae1 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 4.3E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS12000 5b03bc4f41c090e9a8d71286bdfd1ae1 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 4.3E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS12000 5b03bc4f41c090e9a8d71286bdfd1ae1 242 Gene3D G3DSA:1.10.10.10 2 71 2.2E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12000 5b03bc4f41c090e9a8d71286bdfd1ae1 242 SMART SM00345 14 73 5.5E-21 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS12000 5b03bc4f41c090e9a8d71286bdfd1ae1 242 SUPERFAMILY SSF46785 2 84 1.28E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12000 5b03bc4f41c090e9a8d71286bdfd1ae1 242 SUPERFAMILY SSF64288 61 240 5.34E-62 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain GTHT12_RS12000 5b03bc4f41c090e9a8d71286bdfd1ae1 242 SMART SM00866 94 233 5.3E-49 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 GTHT12_RS12000 5b03bc4f41c090e9a8d71286bdfd1ae1 242 Gene3D G3DSA:3.40.1410.10 72 239 1.2E-61 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain GTHT12_RS12000 5b03bc4f41c090e9a8d71286bdfd1ae1 242 TIGRFAM TIGR02325 C_P_lyase_phnF: phosphonate metabolism transcriptional regulator PhnF 3 237 3.8E-47 T 06-07-2017 IPR012702 Phosphonate C-P lyase system, transcriptional regulator PhnF GTHT12_RS05980 be9d4a7e24fa15baef19dcf4c5c30175 304 SMART SM00363 15 79 4.6E-10 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS05980 be9d4a7e24fa15baef19dcf4c5c30175 304 Gene3D G3DSA:3.10.290.10 15 63 6.9E-15 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS05980 be9d4a7e24fa15baef19dcf4c5c30175 304 Pfam PF01479 S4 domain 15 61 1.3E-11 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS05980 be9d4a7e24fa15baef19dcf4c5c30175 304 SUPERFAMILY SSF55174 15 102 6.28E-14 T 06-07-2017 GTHT12_RS05980 be9d4a7e24fa15baef19dcf4c5c30175 304 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 134 148 - T 06-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS05980 be9d4a7e24fa15baef19dcf4c5c30175 304 SUPERFAMILY SSF55120 73 301 8.43E-82 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS05980 be9d4a7e24fa15baef19dcf4c5c30175 304 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 11 301 1.6E-104 T 06-07-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS05980 be9d4a7e24fa15baef19dcf4c5c30175 304 Pfam PF00849 RNA pseudouridylate synthase 88 242 1.9E-37 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS14410 b5bc7c06df56d965a12799cdcf93b876 68 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 41 55 - T 06-07-2017 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 GTHT12_RS14410 b5bc7c06df56d965a12799cdcf93b876 68 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 23 32 - T 06-07-2017 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 GTHT12_RS14410 b5bc7c06df56d965a12799cdcf93b876 68 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 8 62 2.5E-24 T 06-07-2017 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 GTHT12_RS05525 7602565038dfac0292606db463e326de 377 PIRSF PIRSF005962 1 375 3.5E-107 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 GTHT12_RS05525 7602565038dfac0292606db463e326de 377 Pfam PF07687 Peptidase dimerisation domain 181 275 1.7E-9 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS05525 7602565038dfac0292606db463e326de 377 SUPERFAMILY SSF55031 179 288 2.62E-27 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS05525 7602565038dfac0292606db463e326de 377 SUPERFAMILY SSF53187 5 190 1.93E-67 T 06-07-2017 GTHT12_RS05525 7602565038dfac0292606db463e326de 377 SUPERFAMILY SSF53187 291 367 1.93E-67 T 06-07-2017 GTHT12_RS05525 7602565038dfac0292606db463e326de 377 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 8 360 1.9E-85 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 GTHT12_RS05525 7602565038dfac0292606db463e326de 377 Gene3D G3DSA:3.30.70.360 176 290 4.8E-37 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS05525 7602565038dfac0292606db463e326de 377 Pfam PF01546 Peptidase family M20/M25/M40 68 365 7.4E-24 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 GTHT12_RS05525 7602565038dfac0292606db463e326de 377 Hamap MF_01692 N-acetyldiaminopimelate deacetylase. 4 373 64.508 T 06-07-2017 IPR023905 Acetyldiaminopimelate deacetylase GO:0009089|GO:0050118 KEGG: 00300+3.5.1.47|MetaCyc: PWY-2941 GTHT12_RS05525 7602565038dfac0292606db463e326de 377 Gene3D G3DSA:3.40.630.10 291 368 1.6E-75 T 06-07-2017 GTHT12_RS05525 7602565038dfac0292606db463e326de 377 Gene3D G3DSA:3.40.630.10 7 171 1.6E-75 T 06-07-2017 GTHT12_RS01060 ffb833429f7a142dbce0347bdcd9cac9 328 Gene3D G3DSA:3.40.50.1980 174 325 6.0E-37 T 06-07-2017 GTHT12_RS01060 ffb833429f7a142dbce0347bdcd9cac9 328 Gene3D G3DSA:3.40.50.1980 54 172 3.2E-26 T 06-07-2017 GTHT12_RS01060 ffb833429f7a142dbce0347bdcd9cac9 328 Pfam PF01497 Periplasmic binding protein 103 298 4.8E-34 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 GTHT12_RS01060 ffb833429f7a142dbce0347bdcd9cac9 328 SUPERFAMILY SSF53807 54 321 1.61E-59 T 06-07-2017 GTHT12_RS00635 4f84576c15889c09aa8bfe079ffafd41 140 SUPERFAMILY SSF50249 2 136 4.71E-50 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS00635 4f84576c15889c09aa8bfe079ffafd41 140 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00635 4f84576c15889c09aa8bfe079ffafd41 140 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 41.256 T 06-07-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00635 4f84576c15889c09aa8bfe079ffafd41 140 PIRSF PIRSF002133 1 137 3.3E-49 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00635 4f84576c15889c09aa8bfe079ffafd41 140 PRINTS PR01034 Ribosomal protein S12 signature 123 135 1.2E-59 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00635 4f84576c15889c09aa8bfe079ffafd41 140 PRINTS PR01034 Ribosomal protein S12 signature 55 70 1.2E-59 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00635 4f84576c15889c09aa8bfe079ffafd41 140 PRINTS PR01034 Ribosomal protein S12 signature 71 90 1.2E-59 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00635 4f84576c15889c09aa8bfe079ffafd41 140 PRINTS PR01034 Ribosomal protein S12 signature 40 55 1.2E-59 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00635 4f84576c15889c09aa8bfe079ffafd41 140 PRINTS PR01034 Ribosomal protein S12 signature 107 123 1.2E-59 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00635 4f84576c15889c09aa8bfe079ffafd41 140 PRINTS PR01034 Ribosomal protein S12 signature 90 107 1.2E-59 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00635 4f84576c15889c09aa8bfe079ffafd41 140 Gene3D G3DSA:2.40.50.140 1 137 5.6E-64 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS00635 4f84576c15889c09aa8bfe079ffafd41 140 Pfam PF00164 Ribosomal protein S12/S23 2 136 1.1E-40 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00635 4f84576c15889c09aa8bfe079ffafd41 140 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 137 3.4E-69 T 06-07-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS09865 290f758542ec3abdcbe90b1183a99888 506 ProSitePatterns PS01027 Glycosyl hydrolases family 39 active site. 153 162 - T 06-07-2017 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 GTHT12_RS09865 290f758542ec3abdcbe90b1183a99888 506 SUPERFAMILY SSF51011 347 502 5.04E-43 T 06-07-2017 GTHT12_RS09865 290f758542ec3abdcbe90b1183a99888 506 Gene3D G3DSA:3.20.20.80 16 352 5.0E-105 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS09865 290f758542ec3abdcbe90b1183a99888 506 Gene3D G3DSA:2.60.40.1500 353 482 6.7E-46 T 06-07-2017 GTHT12_RS09865 290f758542ec3abdcbe90b1183a99888 506 Pfam PF01229 Glycosyl hydrolases family 39 2 482 1.2E-173 T 06-07-2017 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 GTHT12_RS09865 290f758542ec3abdcbe90b1183a99888 506 PRINTS PR00745 Glycosyl hydrolase family 39 signature 428 442 1.1E-37 T 06-07-2017 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 GTHT12_RS09865 290f758542ec3abdcbe90b1183a99888 506 PRINTS PR00745 Glycosyl hydrolase family 39 signature 133 150 1.1E-37 T 06-07-2017 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 GTHT12_RS09865 290f758542ec3abdcbe90b1183a99888 506 PRINTS PR00745 Glycosyl hydrolase family 39 signature 214 228 1.1E-37 T 06-07-2017 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 GTHT12_RS09865 290f758542ec3abdcbe90b1183a99888 506 PRINTS PR00745 Glycosyl hydrolase family 39 signature 150 166 1.1E-37 T 06-07-2017 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 GTHT12_RS09865 290f758542ec3abdcbe90b1183a99888 506 PRINTS PR00745 Glycosyl hydrolase family 39 signature 288 305 1.1E-37 T 06-07-2017 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 GTHT12_RS09865 290f758542ec3abdcbe90b1183a99888 506 PRINTS PR00745 Glycosyl hydrolase family 39 signature 86 102 1.1E-37 T 06-07-2017 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 GTHT12_RS09865 290f758542ec3abdcbe90b1183a99888 506 PRINTS PR00745 Glycosyl hydrolase family 39 signature 417 428 1.1E-37 T 06-07-2017 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101|Reactome: R-HSA-2206302 GTHT12_RS09865 290f758542ec3abdcbe90b1183a99888 506 SUPERFAMILY SSF51445 14 359 5.02E-97 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS04965 bf38c0447b1ad1edd1f0ccc55c61d80b 338 SUPERFAMILY SSF47413 2 59 2.88E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS04965 bf38c0447b1ad1edd1f0ccc55c61d80b 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 5.6E-19 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS04965 bf38c0447b1ad1edd1f0ccc55c61d80b 338 Gene3D G3DSA:1.10.260.40 2 53 8.3E-26 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS04965 bf38c0447b1ad1edd1f0ccc55c61d80b 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.9E-6 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS04965 bf38c0447b1ad1edd1f0ccc55c61d80b 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.9E-6 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS04965 bf38c0447b1ad1edd1f0ccc55c61d80b 338 Gene3D G3DSA:3.40.50.2300 177 315 4.5E-54 T 06-07-2017 GTHT12_RS04965 bf38c0447b1ad1edd1f0ccc55c61d80b 338 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 06-07-2017 GTHT12_RS04965 bf38c0447b1ad1edd1f0ccc55c61d80b 338 SMART SM00354 1 71 1.4E-30 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS04965 bf38c0447b1ad1edd1f0ccc55c61d80b 338 SUPERFAMILY SSF53822 60 334 7.57E-77 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS04965 bf38c0447b1ad1edd1f0ccc55c61d80b 338 Gene3D G3DSA:3.40.50.2300 54 176 1.6E-41 T 06-07-2017 GTHT12_RS04965 bf38c0447b1ad1edd1f0ccc55c61d80b 338 Pfam PF13377 Periplasmic binding protein-like domain 173 333 1.9E-42 T 06-07-2017 GTHT12_RS17840 f1d7c1c888ebac0a7ff466a3a793497c 460 Gene3D G3DSA:3.30.930.10 6 90 8.1E-154 T 06-07-2017 GTHT12_RS17840 f1d7c1c888ebac0a7ff466a3a793497c 460 Gene3D G3DSA:3.30.930.10 133 364 8.1E-154 T 06-07-2017 GTHT12_RS17840 f1d7c1c888ebac0a7ff466a3a793497c 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 168 185 1.4E-53 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 GTHT12_RS17840 f1d7c1c888ebac0a7ff466a3a793497c 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 147 159 1.4E-53 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 GTHT12_RS17840 f1d7c1c888ebac0a7ff466a3a793497c 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 324 336 1.4E-53 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 GTHT12_RS17840 f1d7c1c888ebac0a7ff466a3a793497c 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 217 227 1.4E-53 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 GTHT12_RS17840 f1d7c1c888ebac0a7ff466a3a793497c 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 200 217 1.4E-53 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 GTHT12_RS17840 f1d7c1c888ebac0a7ff466a3a793497c 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 404 423 1.4E-53 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 GTHT12_RS17840 f1d7c1c888ebac0a7ff466a3a793497c 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 24 38 1.4E-53 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 GTHT12_RS17840 f1d7c1c888ebac0a7ff466a3a793497c 460 Pfam PF03129 Anticodon binding domain 369 456 2.8E-22 T 06-07-2017 IPR004154 Anticodon-binding GTHT12_RS17840 f1d7c1c888ebac0a7ff466a3a793497c 460 SUPERFAMILY SSF55681 4 372 1.53E-128 T 06-07-2017 GTHT12_RS17840 f1d7c1c888ebac0a7ff466a3a793497c 460 SUPERFAMILY SSF52954 356 459 4.53E-32 T 06-07-2017 IPR004154 Anticodon-binding GTHT12_RS17840 f1d7c1c888ebac0a7ff466a3a793497c 460 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 164 339 1.7E-11 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS17840 f1d7c1c888ebac0a7ff466a3a793497c 460 Gene3D G3DSA:3.40.50.800 365 458 5.7E-38 T 06-07-2017 IPR004154 Anticodon-binding GTHT12_RS17840 f1d7c1c888ebac0a7ff466a3a793497c 460 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 4 242 1.4E-93 T 06-07-2017 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 GTHT12_RS17840 f1d7c1c888ebac0a7ff466a3a793497c 460 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 2 459 52.044 T 06-07-2017 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 GTHT12_RS04275 c8acc78443ff1679de64631c6555a63a 412 Gene3D G3DSA:3.40.47.10 263 411 4.0E-69 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS04275 c8acc78443ff1679de64631c6555a63a 412 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 409 8.5E-206 T 06-07-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 GTHT12_RS04275 c8acc78443ff1679de64631c6555a63a 412 SUPERFAMILY SSF53901 214 411 2.14E-80 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS04275 c8acc78443ff1679de64631c6555a63a 412 PIRSF PIRSF000447 1 412 6.5E-193 T 06-07-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 GTHT12_RS04275 c8acc78443ff1679de64631c6555a63a 412 SMART SM00825 Beta-ketoacyl synthase 6 412 2.4E-18 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain GTHT12_RS04275 c8acc78443ff1679de64631c6555a63a 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 368 2.0E-40 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal GTHT12_RS04275 c8acc78443ff1679de64631c6555a63a 412 Gene3D G3DSA:3.40.47.10 8 259 6.5E-80 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS04275 c8acc78443ff1679de64631c6555a63a 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 246 7.9E-64 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal GTHT12_RS04275 c8acc78443ff1679de64631c6555a63a 412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site GTHT12_RS04275 c8acc78443ff1679de64631c6555a63a 412 SUPERFAMILY SSF53901 4 251 1.03E-79 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS17480 1736c60f145d49953f4d6a487e2c479f 285 Gene3D G3DSA:3.40.1380.10 64 191 3.4E-42 T 06-07-2017 GTHT12_RS17480 1736c60f145d49953f4d6a487e2c479f 285 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 2 284 3.3E-114 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 GTHT12_RS17480 1736c60f145d49953f4d6a487e2c479f 285 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 270 283 - T 06-07-2017 IPR023632 ATPase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210 GTHT12_RS17480 1736c60f145d49953f4d6a487e2c479f 285 Gene3D G3DSA:1.10.287.80 19 60 1.1E-32 T 06-07-2017 GTHT12_RS17480 1736c60f145d49953f4d6a487e2c479f 285 Gene3D G3DSA:1.10.287.80 199 232 1.1E-32 T 06-07-2017 GTHT12_RS17480 1736c60f145d49953f4d6a487e2c479f 285 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 6.1E-40 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 GTHT12_RS17480 1736c60f145d49953f4d6a487e2c479f 285 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 6.1E-40 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 GTHT12_RS17480 1736c60f145d49953f4d6a487e2c479f 285 PRINTS PR00126 ATP synthase gamma subunit signature 231 250 6.1E-40 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 GTHT12_RS17480 1736c60f145d49953f4d6a487e2c479f 285 PRINTS PR00126 ATP synthase gamma subunit signature 262 283 6.1E-40 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 GTHT12_RS17480 1736c60f145d49953f4d6a487e2c479f 285 SUPERFAMILY SSF52943 2 284 3.66E-94 T 06-07-2017 IPR023633 ATPase, F1 complex, gamma subunit domain Reactome: R-HSA-163210 GTHT12_RS17480 1736c60f145d49953f4d6a487e2c479f 285 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 284 36.49 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 GTHT12_RS17480 1736c60f145d49953f4d6a487e2c479f 285 Pfam PF00231 ATP synthase 3 284 9.0E-95 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 GTHT12_RS17480 1736c60f145d49953f4d6a487e2c479f 285 Gene3D G3DSA:1.10.287.80 233 279 3.0E-30 T 06-07-2017 GTHT12_RS14830 c5d28c592190423cbc17097d48f4415f 146 PIRSF PIRSF005900 1 146 3.7E-49 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 GTHT12_RS14830 c5d28c592190423cbc17097d48f4415f 146 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 27 43 2.9E-16 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 GTHT12_RS14830 c5d28c592190423cbc17097d48f4415f 146 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 51 67 2.9E-16 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 GTHT12_RS14830 c5d28c592190423cbc17097d48f4415f 146 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 122 140 2.9E-16 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 GTHT12_RS14830 c5d28c592190423cbc17097d48f4415f 146 Pfam PF00210 Ferritin-like domain 8 145 2.2E-35 T 06-07-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 GTHT12_RS14830 c5d28c592190423cbc17097d48f4415f 146 Gene3D G3DSA:1.20.1260.10 3 145 8.8E-60 T 06-07-2017 IPR012347 Ferritin-related GTHT12_RS14830 c5d28c592190423cbc17097d48f4415f 146 ProSitePatterns PS00819 Dps protein family signature 2. 53 67 - T 06-07-2017 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 GTHT12_RS14830 c5d28c592190423cbc17097d48f4415f 146 ProSitePatterns PS00818 Dps protein family signature 1. 27 43 - T 06-07-2017 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 GTHT12_RS14830 c5d28c592190423cbc17097d48f4415f 146 SUPERFAMILY SSF47240 4 145 2.78E-48 T 06-07-2017 IPR009078 Ferritin-like superfamily GTHT12_RS17345 00b5b181928a7b9570501e48fc6f2af3 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 124 143 1.3E-58 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 GTHT12_RS17345 00b5b181928a7b9570501e48fc6f2af3 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 41 59 1.3E-58 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 GTHT12_RS17345 00b5b181928a7b9570501e48fc6f2af3 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 179 199 1.3E-58 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 GTHT12_RS17345 00b5b181928a7b9570501e48fc6f2af3 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 61 84 1.3E-58 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 GTHT12_RS17345 00b5b181928a7b9570501e48fc6f2af3 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 292 318 1.3E-58 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 GTHT12_RS17345 00b5b181928a7b9570501e48fc6f2af3 333 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 2 326 1.7E-137 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 GTHT12_RS17345 00b5b181928a7b9570501e48fc6f2af3 333 SUPERFAMILY SSF53067 142 325 1.1E-48 T 06-07-2017 GTHT12_RS17345 00b5b181928a7b9570501e48fc6f2af3 333 Gene3D G3DSA:3.30.420.40 152 178 2.2E-33 T 06-07-2017 GTHT12_RS17345 00b5b181928a7b9570501e48fc6f2af3 333 Gene3D G3DSA:3.30.420.40 255 309 2.2E-33 T 06-07-2017 GTHT12_RS17345 00b5b181928a7b9570501e48fc6f2af3 333 Gene3D G3DSA:3.90.640.10 179 251 6.6E-30 T 06-07-2017 GTHT12_RS17345 00b5b181928a7b9570501e48fc6f2af3 333 Gene3D G3DSA:3.30.420.40 2 151 3.3E-45 T 06-07-2017 GTHT12_RS17345 00b5b181928a7b9570501e48fc6f2af3 333 SUPERFAMILY SSF53067 2 140 6.91E-40 T 06-07-2017 GTHT12_RS17345 00b5b181928a7b9570501e48fc6f2af3 333 Pfam PF06723 MreB/Mbl protein 4 326 3.8E-150 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 GTHT12_RS11555 34848fe59549083566abe018d0247713 144 Gene3D G3DSA:3.40.50.1380 1 135 5.7E-61 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain GTHT12_RS11555 34848fe59549083566abe018d0247713 144 ProSitePatterns PS01335 Methylglyoxal synthase active site. 54 61 - T 06-07-2017 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 GTHT12_RS11555 34848fe59549083566abe018d0247713 144 PIRSF PIRSF006614 1 140 1.2E-60 T 06-07-2017 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 GTHT12_RS11555 34848fe59549083566abe018d0247713 144 SMART SM00851 14 107 4.2E-26 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain GTHT12_RS11555 34848fe59549083566abe018d0247713 144 SUPERFAMILY SSF52335 1 131 1.96E-53 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain GTHT12_RS11555 34848fe59549083566abe018d0247713 144 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 1 120 36.941 T 06-07-2017 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 GTHT12_RS11555 34848fe59549083566abe018d0247713 144 Pfam PF02142 MGS-like domain 14 107 1.0E-18 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain GTHT12_RS11555 34848fe59549083566abe018d0247713 144 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 1 123 4.9E-57 T 06-07-2017 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 GTHT12_RS10535 dc3c4621f930ad6ed55f04a7fb9f5f48 354 Gene3D G3DSA:2.40.100.10 247 353 4.2E-37 T 06-07-2017 IPR029000 Cyclophilin-like domain GTHT12_RS10535 dc3c4621f930ad6ed55f04a7fb9f5f48 354 Gene3D G3DSA:3.20.20.70 1 233 1.1E-70 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS10535 dc3c4621f930ad6ed55f04a7fb9f5f48 354 SUPERFAMILY SSF50891 244 352 8.34E-31 T 06-07-2017 IPR029000 Cyclophilin-like domain GTHT12_RS10535 dc3c4621f930ad6ed55f04a7fb9f5f48 354 Pfam PF05913 Bacterial protein of unknown function (DUF871) 2 351 8.9E-103 T 06-07-2017 IPR008589 Protein of unknown function DUF871, prokaryotic GTHT12_RS10535 dc3c4621f930ad6ed55f04a7fb9f5f48 354 SUPERFAMILY SSF51445 1 234 1.18E-65 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS01530 5e9ceb56ddeff4742ad4d6d4e7133911 510 Gene3D G3DSA:3.40.50.620 211 385 1.1E-61 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS01530 5e9ceb56ddeff4742ad4d6d4e7133911 510 SUPERFAMILY SSF54810 390 510 8.63E-54 T 06-07-2017 GTHT12_RS01530 5e9ceb56ddeff4742ad4d6d4e7133911 510 PRINTS PR00096 Glutamine amidotransferase superfamily signature 50 59 4.8E-7 T 06-07-2017 GTHT12_RS01530 5e9ceb56ddeff4742ad4d6d4e7133911 510 PRINTS PR00096 Glutamine amidotransferase superfamily signature 77 88 4.8E-7 T 06-07-2017 GTHT12_RS01530 5e9ceb56ddeff4742ad4d6d4e7133911 510 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 4.8E-7 T 06-07-2017 GTHT12_RS01530 5e9ceb56ddeff4742ad4d6d4e7133911 510 PRINTS PR00097 Anthranilate synthase component II signature 50 59 3.8E-5 T 06-07-2017 GTHT12_RS01530 5e9ceb56ddeff4742ad4d6d4e7133911 510 PRINTS PR00097 Anthranilate synthase component II signature 165 178 3.8E-5 T 06-07-2017 GTHT12_RS01530 5e9ceb56ddeff4742ad4d6d4e7133911 510 PRINTS PR00097 Anthranilate synthase component II signature 77 88 3.8E-5 T 06-07-2017 GTHT12_RS01530 5e9ceb56ddeff4742ad4d6d4e7133911 510 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 3 510 56.434 T 06-07-2017 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 GTHT12_RS01530 5e9ceb56ddeff4742ad4d6d4e7133911 510 Gene3D G3DSA:3.30.300.10 386 510 1.2E-54 T 06-07-2017 GTHT12_RS01530 5e9ceb56ddeff4742ad4d6d4e7133911 510 Gene3D G3DSA:3.40.50.880 1 210 5.4E-67 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS01530 5e9ceb56ddeff4742ad4d6d4e7133911 510 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 6 20 4.3E-6 T 06-07-2017 GTHT12_RS01530 5e9ceb56ddeff4742ad4d6d4e7133911 510 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 47 61 4.3E-6 T 06-07-2017 GTHT12_RS01530 5e9ceb56ddeff4742ad4d6d4e7133911 510 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 77 93 4.3E-6 T 06-07-2017 GTHT12_RS01530 5e9ceb56ddeff4742ad4d6d4e7133911 510 Pfam PF00117 Glutamine amidotransferase class-I 8 188 8.3E-43 T 06-07-2017 IPR017926 Glutamine amidotransferase GTHT12_RS01530 5e9ceb56ddeff4742ad4d6d4e7133911 510 SUPERFAMILY SSF52402 185 403 2.21E-63 T 06-07-2017 GTHT12_RS01530 5e9ceb56ddeff4742ad4d6d4e7133911 510 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 6 192 1.2E-82 T 06-07-2017 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 GTHT12_RS01530 5e9ceb56ddeff4742ad4d6d4e7133911 510 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 200 510 6.4E-162 T 06-07-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 GTHT12_RS01530 5e9ceb56ddeff4742ad4d6d4e7133911 510 Pfam PF00958 GMP synthase C terminal domain 418 509 5.0E-47 T 06-07-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 GTHT12_RS01530 5e9ceb56ddeff4742ad4d6d4e7133911 510 SUPERFAMILY SSF52317 4 225 9.17E-61 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS01530 5e9ceb56ddeff4742ad4d6d4e7133911 510 Pfam PF02540 NAD synthase 201 291 2.6E-7 T 06-07-2017 IPR022310 NAD/GMP synthase GTHT12_RS13275 37dc95860fbe43603050a45669462b0b 237 Pfam PF04542 Sigma-70 region 2 54 123 6.2E-18 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13275 37dc95860fbe43603050a45669462b0b 237 SUPERFAMILY SSF88946 9 122 4.58E-37 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13275 37dc95860fbe43603050a45669462b0b 237 SUPERFAMILY SSF88659 139 226 1.27E-19 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13275 37dc95860fbe43603050a45669462b0b 237 PIRSF PIRSF000770 4 237 9.9E-89 T 06-07-2017 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 GTHT12_RS13275 37dc95860fbe43603050a45669462b0b 237 PRINTS PR00046 Major sigma-70 factor signature 78 91 7.5E-14 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13275 37dc95860fbe43603050a45669462b0b 237 PRINTS PR00046 Major sigma-70 factor signature 197 212 7.5E-14 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13275 37dc95860fbe43603050a45669462b0b 237 PRINTS PR00046 Major sigma-70 factor signature 176 188 7.5E-14 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13275 37dc95860fbe43603050a45669462b0b 237 PRINTS PR00046 Major sigma-70 factor signature 212 223 7.5E-14 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13275 37dc95860fbe43603050a45669462b0b 237 Gene3D G3DSA:1.10.601.10 18 118 1.1E-34 T 06-07-2017 GTHT12_RS13275 37dc95860fbe43603050a45669462b0b 237 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 78 91 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13275 37dc95860fbe43603050a45669462b0b 237 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 50 223 1.4E-31 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13275 37dc95860fbe43603050a45669462b0b 237 Pfam PF04545 Sigma-70, region 4 173 223 7.2E-16 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13275 37dc95860fbe43603050a45669462b0b 237 Gene3D G3DSA:1.10.10.10 167 229 8.5E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS13275 37dc95860fbe43603050a45669462b0b 237 TIGRFAM TIGR02846 spore_sigmaK: RNA polymerase sigma-K factor 4 228 9.6E-117 T 06-07-2017 IPR014209 RNA polymerase sigma-K type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13275 37dc95860fbe43603050a45669462b0b 237 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 197 223 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS14235 32845110e6794caab1849277bbded42a 372 SUPERFAMILY SSF48256 2 371 2.75E-136 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 GTHT12_RS14235 32845110e6794caab1849277bbded42a 372 PIRSF PIRSF001369 1 372 2.0E-158 T 06-07-2017 IPR024176 Citrate synthase, bacterial-type GTHT12_RS14235 32845110e6794caab1849277bbded42a 372 PRINTS PR00143 Citrate synthase signature 123 136 4.8E-44 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 GTHT12_RS14235 32845110e6794caab1849277bbded42a 372 PRINTS PR00143 Citrate synthase signature 304 320 4.8E-44 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 GTHT12_RS14235 32845110e6794caab1849277bbded42a 372 PRINTS PR00143 Citrate synthase signature 247 267 4.8E-44 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 GTHT12_RS14235 32845110e6794caab1849277bbded42a 372 PRINTS PR00143 Citrate synthase signature 172 187 4.8E-44 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 GTHT12_RS14235 32845110e6794caab1849277bbded42a 372 PRINTS PR00143 Citrate synthase signature 194 222 4.8E-44 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 GTHT12_RS14235 32845110e6794caab1849277bbded42a 372 PRINTS PR00143 Citrate synthase signature 324 338 4.8E-44 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 GTHT12_RS14235 32845110e6794caab1849277bbded42a 372 Gene3D G3DSA:1.10.580.10 12 233 1.6E-86 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 GTHT12_RS14235 32845110e6794caab1849277bbded42a 372 Gene3D G3DSA:1.10.230.10 234 318 1.2E-36 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 GTHT12_RS14235 32845110e6794caab1849277bbded42a 372 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 5 371 5.5E-167 T 06-07-2017 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 GTHT12_RS14235 32845110e6794caab1849277bbded42a 372 Pfam PF00285 Citrate synthase, C-terminal domain 6 354 4.4E-132 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 GTHT12_RS14235 32845110e6794caab1849277bbded42a 372 ProSitePatterns PS00480 Citrate synthase signature. 254 266 - T 06-07-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 GTHT12_RS12420 59a719f7b1d7bde0d7afbc255eb5be3f 441 Gene3D G3DSA:2.40.50.100 3 95 1.5E-30 T 06-07-2017 GTHT12_RS12420 59a719f7b1d7bde0d7afbc255eb5be3f 441 Gene3D G3DSA:4.10.320.10 118 160 1.2E-19 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS12420 59a719f7b1d7bde0d7afbc255eb5be3f 441 SUPERFAMILY SSF51230 3 95 8.64E-28 T 06-07-2017 IPR011053 Single hybrid motif GTHT12_RS12420 59a719f7b1d7bde0d7afbc255eb5be3f 441 SUPERFAMILY SSF52777 213 433 8.01E-85 T 06-07-2017 GTHT12_RS12420 59a719f7b1d7bde0d7afbc255eb5be3f 441 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 GTHT12_RS12420 59a719f7b1d7bde0d7afbc255eb5be3f 441 Pfam PF00364 Biotin-requiring enzyme 5 77 4.6E-23 T 06-07-2017 IPR000089 Biotin/lipoyl attachment GTHT12_RS12420 59a719f7b1d7bde0d7afbc255eb5be3f 441 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 212 434 4.4E-83 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS12420 59a719f7b1d7bde0d7afbc255eb5be3f 441 SUPERFAMILY SSF47005 113 156 8.37E-12 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS12420 59a719f7b1d7bde0d7afbc255eb5be3f 441 Gene3D G3DSA:3.30.559.10 212 434 1.1E-84 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 GTHT12_RS12420 59a719f7b1d7bde0d7afbc255eb5be3f 441 Pfam PF02817 e3 binding domain 119 152 9.3E-14 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS16620 1209d32fbb43f900fefc6b6b4a9477fb 455 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 211 454 7.2E-90 T 06-07-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS16620 1209d32fbb43f900fefc6b6b4a9477fb 455 SUPERFAMILY SSF53223 14 205 3.52E-73 T 06-07-2017 GTHT12_RS16620 1209d32fbb43f900fefc6b6b4a9477fb 455 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 130 143 - T 06-07-2017 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-70614 GTHT12_RS16620 1209d32fbb43f900fefc6b6b4a9477fb 455 PIRSF PIRSF000185 30 455 7.4E-125 T 06-07-2017 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 GTHT12_RS16620 1209d32fbb43f900fefc6b6b4a9477fb 455 Gene3D G3DSA:1.10.285.10 13 75 1.0E-24 T 06-07-2017 GTHT12_RS16620 1209d32fbb43f900fefc6b6b4a9477fb 455 Gene3D G3DSA:1.10.285.10 381 454 1.5E-24 T 06-07-2017 GTHT12_RS16620 1209d32fbb43f900fefc6b6b4a9477fb 455 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 380 391 2.7E-29 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS16620 1209d32fbb43f900fefc6b6b4a9477fb 455 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 244 264 2.7E-29 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS16620 1209d32fbb43f900fefc6b6b4a9477fb 455 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 122 136 2.7E-29 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS16620 1209d32fbb43f900fefc6b6b4a9477fb 455 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 202 224 2.7E-29 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS16620 1209d32fbb43f900fefc6b6b4a9477fb 455 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 65 193 1.4E-51 T 06-07-2017 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS16620 1209d32fbb43f900fefc6b6b4a9477fb 455 SMART SM00839 213 454 1.4E-93 T 06-07-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS16620 1209d32fbb43f900fefc6b6b4a9477fb 455 SUPERFAMILY SSF51735 211 454 2.51E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS16620 1209d32fbb43f900fefc6b6b4a9477fb 455 Gene3D G3DSA:3.40.50.720 218 380 1.7E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS16620 1209d32fbb43f900fefc6b6b4a9477fb 455 Gene3D G3DSA:3.40.192.10 76 195 1.1E-62 T 06-07-2017 GTHT12_RS11500 5e1d021a677d6e2bc3525e1c744ab890 159 Gene3D G3DSA:3.10.450.40 22 95 1.0E-20 T 06-07-2017 GTHT12_RS11500 5e1d021a677d6e2bc3525e1c744ab890 159 Gene3D G3DSA:3.10.450.40 96 157 1.1E-26 T 06-07-2017 GTHT12_RS11500 5e1d021a677d6e2bc3525e1c744ab890 159 SUPERFAMILY SSF54403 32 95 3.23E-13 T 06-07-2017 GTHT12_RS11500 5e1d021a677d6e2bc3525e1c744ab890 159 SUPERFAMILY SSF54403 95 156 3.23E-17 T 06-07-2017 GTHT12_RS04030 eceb94db611d6996ead9bd4b16d3a31f 123 Pfam PF01022 Bacterial regulatory protein, arsR family 41 88 2.6E-17 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS04030 eceb94db611d6996ead9bd4b16d3a31f 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 1.3E-22 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS04030 eceb94db611d6996ead9bd4b16d3a31f 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 1.3E-22 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS04030 eceb94db611d6996ead9bd4b16d3a31f 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 84 99 1.3E-22 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS04030 eceb94db611d6996ead9bd4b16d3a31f 123 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 67 1.3E-22 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS04030 eceb94db611d6996ead9bd4b16d3a31f 123 SUPERFAMILY SSF46785 22 115 1.46E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS04030 eceb94db611d6996ead9bd4b16d3a31f 123 Gene3D G3DSA:1.10.10.10 5 116 6.6E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS04030 eceb94db611d6996ead9bd4b16d3a31f 123 SMART SM00418 34 113 1.0E-31 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS04030 eceb94db611d6996ead9bd4b16d3a31f 123 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 58 76 - T 06-07-2017 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 GTHT12_RS06385 1697ddda743748db073b89037877d282 334 PRINTS PR00955 Flagellar motor switch protein FliM signature 4 17 2.2E-28 T 06-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 GTHT12_RS06385 1697ddda743748db073b89037877d282 334 PRINTS PR00955 Flagellar motor switch protein FliM signature 213 231 2.2E-28 T 06-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 GTHT12_RS06385 1697ddda743748db073b89037877d282 334 PRINTS PR00955 Flagellar motor switch protein FliM signature 92 108 2.2E-28 T 06-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 GTHT12_RS06385 1697ddda743748db073b89037877d282 334 PRINTS PR00955 Flagellar motor switch protein FliM signature 117 136 2.2E-28 T 06-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 GTHT12_RS06385 1697ddda743748db073b89037877d282 334 SUPERFAMILY SSF103039 48 233 6.67E-31 T 06-07-2017 IPR028976 CheC-like domain GTHT12_RS06385 1697ddda743748db073b89037877d282 334 SUPERFAMILY SSF101801 254 330 4.71E-17 T 06-07-2017 IPR001543 Surface presentation of antigen (SpoA) GTHT12_RS06385 1697ddda743748db073b89037877d282 334 Gene3D G3DSA:3.40.1550.10 49 153 3.1E-4 T 06-07-2017 IPR028976 CheC-like domain GTHT12_RS06385 1697ddda743748db073b89037877d282 334 PIRSF PIRSF002888 3 334 6.6E-113 T 06-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 GTHT12_RS06385 1697ddda743748db073b89037877d282 334 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 255 325 2.6E-20 T 06-07-2017 IPR001543 Surface presentation of antigen (SpoA) GTHT12_RS06385 1697ddda743748db073b89037877d282 334 Gene3D G3DSA:2.30.330.10 243 330 2.9E-15 T 06-07-2017 GTHT12_RS06385 1697ddda743748db073b89037877d282 334 Pfam PF02154 Flagellar motor switch protein FliM 41 231 3.1E-72 T 06-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 GTHT12_RS06385 1697ddda743748db073b89037877d282 334 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 5 325 1.7E-110 T 06-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 GTHT12_RS11835 5d366526949900364ea547af8b755c66 423 SUPERFAMILY SSF51735 190 422 3.15E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS11835 5d366526949900364ea547af8b755c66 423 PIRSF PIRSF000185 3 423 4.0E-175 T 06-07-2017 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 GTHT12_RS11835 5d366526949900364ea547af8b755c66 423 SUPERFAMILY SSF53223 15 192 6.72E-67 T 06-07-2017 GTHT12_RS11835 5d366526949900364ea547af8b755c66 423 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 190 421 1.7E-80 T 06-07-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS11835 5d366526949900364ea547af8b755c66 423 SMART SM00839 192 421 2.6E-97 T 06-07-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS11835 5d366526949900364ea547af8b755c66 423 Gene3D G3DSA:3.40.192.10 46 187 9.0E-57 T 06-07-2017 GTHT12_RS11835 5d366526949900364ea547af8b755c66 423 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 181 203 2.0E-31 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS11835 5d366526949900364ea547af8b755c66 423 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 101 115 2.0E-31 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS11835 5d366526949900364ea547af8b755c66 423 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 349 360 2.0E-31 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS11835 5d366526949900364ea547af8b755c66 423 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 223 243 2.0E-31 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS11835 5d366526949900364ea547af8b755c66 423 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 109 122 - T 06-07-2017 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-70614 GTHT12_RS11835 5d366526949900364ea547af8b755c66 423 Gene3D G3DSA:3.40.50.720 190 422 1.5E-86 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS11835 5d366526949900364ea547af8b755c66 423 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 45 172 3.5E-55 T 06-07-2017 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS04315 cf901ed160cd9b48d3ac8e680c9d7b18 339 Gene3D G3DSA:1.10.3720.10 131 335 1.1E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS04315 cf901ed160cd9b48d3ac8e680c9d7b18 339 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 33 85 3.3E-13 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain GTHT12_RS04315 cf901ed160cd9b48d3ac8e680c9d7b18 339 SUPERFAMILY SSF161098 133 319 1.09E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS04315 cf901ed160cd9b48d3ac8e680c9d7b18 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 155 339 5.6E-34 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS05545 9b3ef7969f53162ee94fccd768ef3471 220 SUPERFAMILY SSF51735 4 136 1.61E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS05545 9b3ef7969f53162ee94fccd768ef3471 220 Gene3D G3DSA:3.40.50.720 2 140 1.7E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS05545 9b3ef7969f53162ee94fccd768ef3471 220 SUPERFAMILY SSF116726 132 216 3.92E-22 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 GTHT12_RS05545 9b3ef7969f53162ee94fccd768ef3471 220 Gene3D G3DSA:3.30.70.1450 151 218 1.3E-21 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 GTHT12_RS05545 9b3ef7969f53162ee94fccd768ef3471 220 Pfam PF02080 TrkA-C domain 151 217 3.1E-17 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 GTHT12_RS05545 9b3ef7969f53162ee94fccd768ef3471 220 Pfam PF02254 TrkA-N domain 6 121 2.8E-31 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 GTHT12_RS12020 d95753ce218aa9a82ce44e621b3d8ac5 241 Pfam PF00072 Response regulator receiver domain 10 118 9.1E-32 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS12020 d95753ce218aa9a82ce44e621b3d8ac5 241 SMART SM00862 159 236 2.3E-29 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS12020 d95753ce218aa9a82ce44e621b3d8ac5 241 Gene3D G3DSA:3.40.50.2300 6 127 1.6E-43 T 06-07-2017 GTHT12_RS12020 d95753ce218aa9a82ce44e621b3d8ac5 241 SMART SM00448 8 118 1.7E-47 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS12020 d95753ce218aa9a82ce44e621b3d8ac5 241 Gene3D G3DSA:1.10.10.10 137 238 2.6E-37 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12020 d95753ce218aa9a82ce44e621b3d8ac5 241 SUPERFAMILY SSF52172 6 194 8.6E-43 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS12020 d95753ce218aa9a82ce44e621b3d8ac5 241 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 236 8.1E-29 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS05220 9d9bccb6309426abc3c1251b09029114 152 Gene3D G3DSA:2.40.50.40 39 106 6.4E-17 T 06-07-2017 GTHT12_RS05220 9d9bccb6309426abc3c1251b09029114 152 Pfam PF04397 LytTr DNA-binding domain 51 144 7.6E-23 T 06-07-2017 IPR007492 LytTR DNA-binding domain GO:0003677 GTHT12_RS05220 9d9bccb6309426abc3c1251b09029114 152 Gene3D G3DSA:2.20.25.10 115 146 2.3E-4 T 06-07-2017 GTHT12_RS05220 9d9bccb6309426abc3c1251b09029114 152 SMART SM00850 48 145 6.7E-28 T 06-07-2017 IPR007492 LytTR DNA-binding domain GO:0003677 GTHT12_RS05845 806ea97bb66c492d3f269cf13fbca3e5 118 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 35 117 1.1E-22 T 06-07-2017 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 GTHT12_RS05845 806ea97bb66c492d3f269cf13fbca3e5 118 Hamap MF_00910 Cell division protein FtsL [ftsL]. 33 117 15.038 T 06-07-2017 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 GTHT12_RS05845 806ea97bb66c492d3f269cf13fbca3e5 118 Pfam PF04977 Septum formation initiator 42 117 2.0E-14 T 06-07-2017 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 GTHT12_RS12230 7fc99d0c1f58642aaa18fc1670b5c187 220 TIGRFAM TIGR02831 spo_II_M: stage II sporulation protein M 10 206 2.5E-75 T 06-07-2017 IPR014196 Stage II sporulation protein M GTHT12_RS12230 7fc99d0c1f58642aaa18fc1670b5c187 220 Pfam PF01944 Stage II sporulation protein M 25 202 8.4E-27 T 06-07-2017 IPR002798 Stage II sporulation protein M-like GTHT12_RS12230 7fc99d0c1f58642aaa18fc1670b5c187 220 PIRSF PIRSF038973 1 213 1.8E-90 T 06-07-2017 IPR014196 Stage II sporulation protein M GTHT12_RS03970 fb577a16ff339eef91f427246d52b1c0 363 SMART SM00382 31 214 1.4E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS03970 fb577a16ff339eef91f427246d52b1c0 363 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 37 308 9.8E-109 T 06-07-2017 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 GTHT12_RS03970 fb577a16ff339eef91f427246d52b1c0 363 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS03970 fb577a16ff339eef91f427246d52b1c0 363 Pfam PF08402 TOBE domain 275 344 3.0E-8 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 GTHT12_RS03970 fb577a16ff339eef91f427246d52b1c0 363 Gene3D G3DSA:3.40.50.300 3 239 2.0E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03970 fb577a16ff339eef91f427246d52b1c0 363 SUPERFAMILY SSF50331 239 344 8.5E-14 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal GTHT12_RS03970 fb577a16ff339eef91f427246d52b1c0 363 Pfam PF00005 ABC transporter 22 164 1.8E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS03970 fb577a16ff339eef91f427246d52b1c0 363 SUPERFAMILY SSF52540 6 247 7.51E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06175 29be92a633caffbc53f56ef881337b97 328 PIRSF PIRSF002465 1 328 1.0E-131 T 06-07-2017 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 GTHT12_RS06175 29be92a633caffbc53f56ef881337b97 328 Gene3D G3DSA:3.40.718.10 1 326 6.6E-141 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 GTHT12_RS06175 29be92a633caffbc53f56ef881337b97 328 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 326 2.5E-137 T 06-07-2017 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 GTHT12_RS06175 29be92a633caffbc53f56ef881337b97 328 SUPERFAMILY SSF53659 2 326 4.93E-109 T 06-07-2017 GTHT12_RS06175 29be92a633caffbc53f56ef881337b97 328 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 328 155.993 T 06-07-2017 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 GTHT12_RS06175 29be92a633caffbc53f56ef881337b97 328 Pfam PF02504 Fatty acid synthesis protein 1 317 2.5E-126 T 06-07-2017 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 GTHT12_RS17850 c78d884513ea04196f75c496e79bf95c 398 SUPERFAMILY SSF103473 7 396 4.45E-86 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS17850 c78d884513ea04196f75c496e79bf95c 398 ProSitePatterns PS00217 Sugar transport proteins signature 2. 107 132 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 GTHT12_RS17850 c78d884513ea04196f75c496e79bf95c 398 ProSitePatterns PS00216 Sugar transport proteins signature 1. 268 283 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 GTHT12_RS17850 c78d884513ea04196f75c496e79bf95c 398 Pfam PF07690 Major Facilitator Superfamily 20 261 5.9E-39 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS17850 c78d884513ea04196f75c496e79bf95c 398 Gene3D G3DSA:1.20.1250.20 213 396 7.3E-24 T 06-07-2017 GTHT12_RS17850 c78d884513ea04196f75c496e79bf95c 398 Gene3D G3DSA:1.20.1250.20 10 195 2.2E-35 T 06-07-2017 GTHT12_RS14895 978e11d70e0e9c7f99455e5d5cf92a08 586 SUPERFAMILY SSF52518 10 184 4.42E-39 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS14895 978e11d70e0e9c7f99455e5d5cf92a08 586 Pfam PF16582 Middle domain of thiamine pyrophosphate 219 401 3.0E-15 T 06-07-2017 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 GTHT12_RS14895 978e11d70e0e9c7f99455e5d5cf92a08 586 Gene3D G3DSA:3.40.50.970 359 565 1.4E-38 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS14895 978e11d70e0e9c7f99455e5d5cf92a08 586 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 2 568 37.545 T 06-07-2017 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 GTHT12_RS14895 978e11d70e0e9c7f99455e5d5cf92a08 586 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 10 178 1.2E-40 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 GTHT12_RS14895 978e11d70e0e9c7f99455e5d5cf92a08 586 PIRSF PIRSF004983 1 575 8.6E-196 T 06-07-2017 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 GTHT12_RS14895 978e11d70e0e9c7f99455e5d5cf92a08 586 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 9 444 9.2E-157 T 06-07-2017 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 GTHT12_RS14895 978e11d70e0e9c7f99455e5d5cf92a08 586 Gene3D G3DSA:3.40.50.970 10 182 1.7E-52 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS14895 978e11d70e0e9c7f99455e5d5cf92a08 586 Gene3D G3DSA:3.40.50.1220 206 358 9.7E-5 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS14895 978e11d70e0e9c7f99455e5d5cf92a08 586 SUPERFAMILY SSF52518 380 573 5.16E-36 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS14895 978e11d70e0e9c7f99455e5d5cf92a08 586 SUPERFAMILY SSF52467 165 365 6.54E-14 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS14895 978e11d70e0e9c7f99455e5d5cf92a08 586 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 415 550 1.5E-12 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 GTHT12_RS14315 bac53c6771d64150c595949ee478629e 364 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 138 4.6E-28 T 06-07-2017 IPR000587 Creatinase, N-terminal GO:0016787 GTHT12_RS14315 bac53c6771d64150c595949ee478629e 364 PRINTS PR00599 Methionine aminopeptidase-1 signature 316 328 3.4E-6 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase GTHT12_RS14315 bac53c6771d64150c595949ee478629e 364 PRINTS PR00599 Methionine aminopeptidase-1 signature 218 234 3.4E-6 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase GTHT12_RS14315 bac53c6771d64150c595949ee478629e 364 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 294 306 - T 06-07-2017 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site GTHT12_RS14315 bac53c6771d64150c595949ee478629e 364 Pfam PF00557 Metallopeptidase family M24 146 348 8.7E-66 T 06-07-2017 IPR000994 Peptidase M24, structural domain GTHT12_RS14315 bac53c6771d64150c595949ee478629e 364 SUPERFAMILY SSF53092 1 136 3.01E-35 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal GTHT12_RS14315 bac53c6771d64150c595949ee478629e 364 SUPERFAMILY SSF55920 137 364 1.27E-79 T 06-07-2017 IPR000994 Peptidase M24, structural domain GTHT12_RS14315 bac53c6771d64150c595949ee478629e 364 Gene3D G3DSA:3.40.350.10 1 136 7.3E-35 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal GTHT12_RS14315 bac53c6771d64150c595949ee478629e 364 Gene3D G3DSA:3.90.230.10 138 363 2.9E-80 T 06-07-2017 IPR000994 Peptidase M24, structural domain GTHT12_RS16230 baeb8723d417140d7d0a13d9d81d2499 528 SUPERFAMILY SSF64518 148 259 1.15E-22 T 06-07-2017 GTHT12_RS16230 baeb8723d417140d7d0a13d9d81d2499 528 SUPERFAMILY SSF64518 347 521 1.15E-22 T 06-07-2017 GTHT12_RS16230 baeb8723d417140d7d0a13d9d81d2499 528 PRINTS PR01005 Flagellar hook-associated protein signature 14 37 7.5E-6 T 06-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 GTHT12_RS16230 baeb8723d417140d7d0a13d9d81d2499 528 PRINTS PR01005 Flagellar hook-associated protein signature 167 191 7.5E-6 T 06-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 GTHT12_RS16230 baeb8723d417140d7d0a13d9d81d2499 528 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 7 521 1.3E-111 T 06-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 GTHT12_RS16230 baeb8723d417140d7d0a13d9d81d2499 528 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 465 521 2.4E-13 T 06-07-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain GTHT12_RS16230 baeb8723d417140d7d0a13d9d81d2499 528 Pfam PF00460 Flagella basal body rod protein 8 38 3.2E-8 T 06-07-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 GTHT12_RS12330 7bbce207b332c9d387e5a3e706a2ec27 304 SUPERFAMILY SSF53187 24 102 3.64E-31 T 06-07-2017 GTHT12_RS12330 7bbce207b332c9d387e5a3e706a2ec27 304 SUPERFAMILY SSF53187 202 291 3.64E-31 T 06-07-2017 GTHT12_RS12330 7bbce207b332c9d387e5a3e706a2ec27 304 Gene3D G3DSA:3.30.70.360 87 201 9.2E-28 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS12330 7bbce207b332c9d387e5a3e706a2ec27 304 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 28 278 1.8E-64 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 GTHT12_RS12330 7bbce207b332c9d387e5a3e706a2ec27 304 Pfam PF01546 Peptidase family M20/M25/M40 28 287 2.5E-14 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 GTHT12_RS12330 7bbce207b332c9d387e5a3e706a2ec27 304 Gene3D G3DSA:3.40.630.10 202 293 2.2E-36 T 06-07-2017 GTHT12_RS12330 7bbce207b332c9d387e5a3e706a2ec27 304 Gene3D G3DSA:3.40.630.10 26 83 2.2E-36 T 06-07-2017 GTHT12_RS12330 7bbce207b332c9d387e5a3e706a2ec27 304 SUPERFAMILY SSF55031 89 180 5.53E-23 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS12330 7bbce207b332c9d387e5a3e706a2ec27 304 Pfam PF07687 Peptidase dimerisation domain 94 179 1.1E-7 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS18270 0d8eeb5e172c5fcae6b045c7a2a082c1 181 Gene3D G3DSA:2.60.120.10 60 180 4.8E-47 T 06-07-2017 IPR014710 RmlC-like jelly roll fold GTHT12_RS18270 0d8eeb5e172c5fcae6b045c7a2a082c1 181 Pfam PF07883 Cupin domain 85 160 1.9E-13 T 06-07-2017 IPR013096 Cupin 2, conserved barrel GTHT12_RS18270 0d8eeb5e172c5fcae6b045c7a2a082c1 181 SUPERFAMILY SSF51182 42 165 6.69E-26 T 06-07-2017 IPR011051 RmlC-like cupin domain GTHT12_RS15820 68156e327555204b978f9c0d9abc354b 492 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 5 272 8.9E-99 T 06-07-2017 IPR024674 HpaB/PvcC/4-BUDH N-terminal GTHT12_RS15820 68156e327555204b978f9c0d9abc354b 492 TIGRFAM TIGR02309 HpaB-1: 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component 3 480 5.2E-232 T 06-07-2017 IPR012687 4-HPA 3-monooxygenase large component, Deinococcus-type GO:0010124|GO:0016712|GO:0050660 KEGG: 00350+1.14.14.9|MetaCyc: PWY-7431 GTHT12_RS15820 68156e327555204b978f9c0d9abc354b 492 Gene3D G3DSA:2.40.110.10 145 264 3.6E-47 T 06-07-2017 GTHT12_RS15820 68156e327555204b978f9c0d9abc354b 492 SUPERFAMILY SSF56645 4 273 4.79E-81 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 GTHT12_RS15820 68156e327555204b978f9c0d9abc354b 492 Gene3D G3DSA:1.10.3140.10 3 143 4.5E-46 T 06-07-2017 GTHT12_RS15820 68156e327555204b978f9c0d9abc354b 492 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 279 478 4.7E-67 T 06-07-2017 IPR024719 HpaB/PvcC/4-BUDH C-terminal GTHT12_RS15820 68156e327555204b978f9c0d9abc354b 492 PIRSF PIRSF000331 1 487 1.6E-176 T 06-07-2017 IPR004925 HpaB/PvcC/4-BUDH GTHT12_RS15820 68156e327555204b978f9c0d9abc354b 492 Gene3D G3DSA:1.20.140.10 265 479 2.0E-61 T 06-07-2017 GTHT12_RS15820 68156e327555204b978f9c0d9abc354b 492 SUPERFAMILY SSF47203 263 479 1.73E-64 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS12905 b00b4595a095ea9a2081c5fde0a47fb3 699 SUPERFAMILY SSF56519 52 114 2.75E-35 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 GTHT12_RS12905 b00b4595a095ea9a2081c5fde0a47fb3 699 SUPERFAMILY SSF56519 186 317 2.75E-35 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 GTHT12_RS12905 b00b4595a095ea9a2081c5fde0a47fb3 699 Pfam PF00905 Penicillin binding protein transpeptidase domain 350 675 8.6E-71 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 GTHT12_RS12905 b00b4595a095ea9a2081c5fde0a47fb3 699 Gene3D G3DSA:3.90.1310.10 197 316 6.7E-27 T 06-07-2017 GTHT12_RS12905 b00b4595a095ea9a2081c5fde0a47fb3 699 SUPERFAMILY SSF56601 269 679 2.91E-69 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS12905 b00b4595a095ea9a2081c5fde0a47fb3 699 Pfam PF03717 Penicillin-binding Protein dimerisation domain 56 302 9.9E-40 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 GTHT12_RS12905 b00b4595a095ea9a2081c5fde0a47fb3 699 Gene3D G3DSA:3.40.710.10 317 681 1.6E-77 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS10870 ab20f74b19acd9963b0d31ae2fef3b74 448 SMART SM00304 182 234 0.0027 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS10870 ab20f74b19acd9963b0d31ae2fef3b74 448 SUPERFAMILY SSF47384 225 308 8.83E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS10870 ab20f74b19acd9963b0d31ae2fef3b74 448 SMART SM00387 354 446 2.7E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS10870 ab20f74b19acd9963b0d31ae2fef3b74 448 Pfam PF00672 HAMP domain 168 231 2.6E-7 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS10870 ab20f74b19acd9963b0d31ae2fef3b74 448 Gene3D G3DSA:1.10.287.130 234 292 1.8E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS10870 ab20f74b19acd9963b0d31ae2fef3b74 448 Pfam PF00512 His Kinase A (phospho-acceptor) domain 243 303 2.5E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS10870 ab20f74b19acd9963b0d31ae2fef3b74 448 SUPERFAMILY SSF55874 297 442 1.64E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS10870 ab20f74b19acd9963b0d31ae2fef3b74 448 SUPERFAMILY SSF158472 184 231 5.23E-5 T 06-07-2017 GTHT12_RS10870 ab20f74b19acd9963b0d31ae2fef3b74 448 Gene3D G3DSA:3.30.565.10 293 442 6.9E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS10870 ab20f74b19acd9963b0d31ae2fef3b74 448 SMART SM00388 242 307 4.5E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS02315 1f1cc76c9484cd7fc27ee6249f6a991a 212 TIGRFAM TIGR03202 pucB: xanthine dehydrogenase accessory protein pucB 6 194 2.5E-73 T 06-07-2017 IPR017615 Xanthine dehydrogenase, accessory protein PucB GTHT12_RS02315 1f1cc76c9484cd7fc27ee6249f6a991a 212 Pfam PF12804 MobA-like NTP transferase domain 8 168 3.3E-33 T 06-07-2017 IPR025877 MobA-like NTP transferase GTHT12_RS02315 1f1cc76c9484cd7fc27ee6249f6a991a 212 SUPERFAMILY SSF53448 6 195 1.93E-21 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS02315 1f1cc76c9484cd7fc27ee6249f6a991a 212 Gene3D G3DSA:3.90.550.10 5 197 2.1E-27 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS09340 e243c7483d8910ea121b6e595899a444 234 SUPERFAMILY SSF55486 22 229 4.39E-37 T 06-07-2017 GTHT12_RS09340 e243c7483d8910ea121b6e595899a444 234 Gene3D G3DSA:3.40.390.10 41 229 3.0E-31 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 GTHT12_RS04230 b95ada1692a7a946eaa8b97ef49c0e18 312 Gene3D G3DSA:3.40.50.1370 6 146 8.7E-60 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GTHT12_RS04230 b95ada1692a7a946eaa8b97ef49c0e18 312 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 156 310 9.7E-61 T 06-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 GTHT12_RS04230 b95ada1692a7a946eaa8b97ef49c0e18 312 PRINTS PR00102 Ornithine carbamoyltransferase signature 53 67 1.3E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GTHT12_RS04230 b95ada1692a7a946eaa8b97ef49c0e18 312 PRINTS PR00102 Ornithine carbamoyltransferase signature 291 302 1.3E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GTHT12_RS04230 b95ada1692a7a946eaa8b97ef49c0e18 312 PRINTS PR00102 Ornithine carbamoyltransferase signature 229 239 1.3E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GTHT12_RS04230 b95ada1692a7a946eaa8b97ef49c0e18 312 PRINTS PR00102 Ornithine carbamoyltransferase signature 126 140 1.3E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GTHT12_RS04230 b95ada1692a7a946eaa8b97ef49c0e18 312 PRINTS PR00102 Ornithine carbamoyltransferase signature 86 99 1.3E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GTHT12_RS04230 b95ada1692a7a946eaa8b97ef49c0e18 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 277 300 2.7E-27 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GTHT12_RS04230 b95ada1692a7a946eaa8b97ef49c0e18 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 137 148 2.7E-27 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GTHT12_RS04230 b95ada1692a7a946eaa8b97ef49c0e18 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 274 2.7E-27 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GTHT12_RS04230 b95ada1692a7a946eaa8b97ef49c0e18 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 55 74 2.7E-27 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GTHT12_RS04230 b95ada1692a7a946eaa8b97ef49c0e18 312 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 10 311 1.4E-137 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GTHT12_RS04230 b95ada1692a7a946eaa8b97ef49c0e18 312 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 9 312 83.392 T 06-07-2017 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 GTHT12_RS04230 b95ada1692a7a946eaa8b97ef49c0e18 312 Gene3D G3DSA:3.40.50.1370 147 299 3.3E-68 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GTHT12_RS04230 b95ada1692a7a946eaa8b97ef49c0e18 312 SUPERFAMILY SSF53671 5 312 5.5E-114 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GTHT12_RS04230 b95ada1692a7a946eaa8b97ef49c0e18 312 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 55 62 - T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GTHT12_RS04230 b95ada1692a7a946eaa8b97ef49c0e18 312 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 10 150 1.0E-54 T 06-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 GTHT12_RS12725 f8660687c4e052698ee125a986558eb4 487 SUPERFAMILY SSF53383 7 482 2.45E-120 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS12725 f8660687c4e052698ee125a986558eb4 487 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 6 484 61.659 T 06-07-2017 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 GTHT12_RS12725 f8660687c4e052698ee125a986558eb4 487 Pfam PF02347 Glycine cleavage system P-protein 33 303 2.6E-11 T 06-07-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 GTHT12_RS12725 f8660687c4e052698ee125a986558eb4 487 Gene3D G3DSA:3.40.640.10 84 287 3.8E-42 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS12725 f8660687c4e052698ee125a986558eb4 487 Gene3D G3DSA:3.40.640.10 365 366 3.8E-42 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS12725 f8660687c4e052698ee125a986558eb4 487 Gene3D G3DSA:3.40.640.10 431 450 3.8E-42 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS10950 25292bfc0c3841f92d4158a0fb717214 121 Pfam PF00581 Rhodanese-like domain 33 121 2.2E-17 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS10950 25292bfc0c3841f92d4158a0fb717214 121 SMART SM00450 31 121 3.8E-23 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS10950 25292bfc0c3841f92d4158a0fb717214 121 SUPERFAMILY SSF52821 9 120 7.46E-35 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS10950 25292bfc0c3841f92d4158a0fb717214 121 Gene3D G3DSA:3.40.250.10 12 121 1.8E-32 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS13930 17d281059c24cfc3227979e93d452520 147 Pfam PF01047 MarR family 37 95 4.2E-18 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS13930 17d281059c24cfc3227979e93d452520 147 SUPERFAMILY SSF46785 12 145 9.79E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS13930 17d281059c24cfc3227979e93d452520 147 Gene3D G3DSA:1.10.10.10 7 146 4.6E-46 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS13930 17d281059c24cfc3227979e93d452520 147 SMART SM00347 30 130 6.5E-28 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS04150 5186c95017a8e62ce26a62e6d8e4b8a5 341 Gene3D G3DSA:3.20.20.70 9 311 8.2E-78 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS04150 5186c95017a8e62ce26a62e6d8e4b8a5 341 SMART SM00729 18 223 2.9E-9 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 GTHT12_RS04150 5186c95017a8e62ce26a62e6d8e4b8a5 341 SUPERFAMILY SSF102114 10 289 2.75E-76 T 06-07-2017 GTHT12_RS04150 5186c95017a8e62ce26a62e6d8e4b8a5 341 Pfam PF13353 4Fe-4S single cluster domain 26 132 4.4E-5 T 06-07-2017 GTHT12_RS04150 5186c95017a8e62ce26a62e6d8e4b8a5 341 Hamap MF_01225_B Cyclic pyranopterin monophosphate synthase [moaA]. 9 341 39.799 T 06-07-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 GTHT12_RS04150 5186c95017a8e62ce26a62e6d8e4b8a5 341 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 24 35 - T 06-07-2017 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 GTHT12_RS04150 5186c95017a8e62ce26a62e6d8e4b8a5 341 Pfam PF06463 Molybdenum Cofactor Synthesis C 194 320 2.7E-37 T 06-07-2017 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 GTHT12_RS04150 5186c95017a8e62ce26a62e6d8e4b8a5 341 Pfam PF04055 Radical SAM superfamily 24 186 8.6E-29 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 GTHT12_RS04150 5186c95017a8e62ce26a62e6d8e4b8a5 341 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 10 341 2.7E-115 T 06-07-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 GTHT12_RS14415 d956d2952ca52a5040b71484514532ab 401 Pfam PF02926 THUMP domain 42 162 1.9E-21 T 06-07-2017 IPR004114 THUMP domain GO:0003723 GTHT12_RS14415 d956d2952ca52a5040b71484514532ab 401 SUPERFAMILY SSF52402 174 389 3.31E-51 T 06-07-2017 GTHT12_RS14415 d956d2952ca52a5040b71484514532ab 401 SMART SM00981 74 165 1.4E-23 T 06-07-2017 IPR004114 THUMP domain GO:0003723 GTHT12_RS14415 d956d2952ca52a5040b71484514532ab 401 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 401 163.633 T 06-07-2017 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 GTHT12_RS14415 d956d2952ca52a5040b71484514532ab 401 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 6 371 7.7E-130 T 06-07-2017 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 GTHT12_RS14415 d956d2952ca52a5040b71484514532ab 401 SUPERFAMILY SSF143437 3 173 2.62E-54 T 06-07-2017 GTHT12_RS14415 d956d2952ca52a5040b71484514532ab 401 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 175 371 1.0E-68 T 06-07-2017 IPR020536 Thil, AANH domain GO:0004810 GTHT12_RS14415 d956d2952ca52a5040b71484514532ab 401 Gene3D G3DSA:3.40.50.620 173 333 2.7E-52 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS05870 5f77847ff4ab26a4c4e4670e83f16121 324 Pfam PF00953 Glycosyl transferase family 4 83 248 2.1E-39 T 06-07-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 GTHT12_RS05870 5f77847ff4ab26a4c4e4670e83f16121 324 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 17 324 2.0E-122 T 06-07-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 GTHT12_RS05870 5f77847ff4ab26a4c4e4670e83f16121 324 ProSitePatterns PS01348 MraY family signature 2. 168 179 - T 06-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 GTHT12_RS05870 5f77847ff4ab26a4c4e4670e83f16121 324 ProSitePatterns PS01347 MraY family signature 1. 48 60 - T 06-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 GTHT12_RS05870 5f77847ff4ab26a4c4e4670e83f16121 324 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 5 322 24.712 T 06-07-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 GTHT12_RS05870 5f77847ff4ab26a4c4e4670e83f16121 324 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 48 60 1.4E-5 T 06-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 GTHT12_RS06245 eb137bb3c093989828b2fee9d89f15db 116 PRINTS PR00061 Ribosomal protein L19 signature 4 33 9.8E-43 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS06245 eb137bb3c093989828b2fee9d89f15db 116 PRINTS PR00061 Ribosomal protein L19 signature 88 113 9.8E-43 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS06245 eb137bb3c093989828b2fee9d89f15db 116 PRINTS PR00061 Ribosomal protein L19 signature 34 63 9.8E-43 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS06245 eb137bb3c093989828b2fee9d89f15db 116 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 33.036 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS06245 eb137bb3c093989828b2fee9d89f15db 116 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 06-07-2017 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS06245 eb137bb3c093989828b2fee9d89f15db 116 Pfam PF01245 Ribosomal protein L19 4 113 6.6E-55 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS06245 eb137bb3c093989828b2fee9d89f15db 116 PIRSF PIRSF002191 1 116 2.1E-52 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS06245 eb137bb3c093989828b2fee9d89f15db 116 SUPERFAMILY SSF50104 1 114 1.2E-49 T 06-07-2017 IPR008991 Translation protein SH3-like domain GTHT12_RS06245 eb137bb3c093989828b2fee9d89f15db 116 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 1.1E-52 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS17890 2a8d7bdc92470ae2a468bbdee49684f1 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 110 2.6E-24 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 GTHT12_RS17890 2a8d7bdc92470ae2a468bbdee49684f1 218 Gene3D G3DSA:1.10.3720.10 11 215 4.9E-56 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS17890 2a8d7bdc92470ae2a468bbdee49684f1 218 SUPERFAMILY SSF161098 13 207 5.63E-49 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS17890 2a8d7bdc92470ae2a468bbdee49684f1 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 215 6.4E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS10365 dad9443dc29cb0aee3425b188d118a95 532 Gene3D G3DSA:3.30.565.10 392 524 3.0E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS10365 dad9443dc29cb0aee3425b188d118a95 532 Pfam PF13426 PAS domain 219 310 1.2E-9 T 06-07-2017 IPR000014 PAS domain GTHT12_RS10365 dad9443dc29cb0aee3425b188d118a95 532 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 212 275 5.4E-7 T 06-07-2017 IPR000014 PAS domain GTHT12_RS10365 dad9443dc29cb0aee3425b188d118a95 532 Gene3D G3DSA:3.30.450.20 28 164 1.0E-51 T 06-07-2017 GTHT12_RS10365 dad9443dc29cb0aee3425b188d118a95 532 SUPERFAMILY SSF55874 393 524 7.47E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS10365 dad9443dc29cb0aee3425b188d118a95 532 SUPERFAMILY SSF103190 34 163 1.73E-41 T 06-07-2017 IPR029151 Periplasmic sensor domain-like GTHT12_RS10365 dad9443dc29cb0aee3425b188d118a95 532 Gene3D G3DSA:3.30.450.20 209 314 6.8E-14 T 06-07-2017 GTHT12_RS10365 dad9443dc29cb0aee3425b188d118a95 532 SUPERFAMILY SSF55890 318 404 3.53E-12 T 06-07-2017 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 GTHT12_RS10365 dad9443dc29cb0aee3425b188d118a95 532 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 416 524 9.0E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS10365 dad9443dc29cb0aee3425b188d118a95 532 SUPERFAMILY SSF55785 208 307 4.89E-14 T 06-07-2017 IPR000014 PAS domain GTHT12_RS10365 dad9443dc29cb0aee3425b188d118a95 532 SMART SM00091 208 275 2.1E-8 T 06-07-2017 IPR000014 PAS domain GTHT12_RS10365 dad9443dc29cb0aee3425b188d118a95 532 SMART SM00387 415 526 1.9E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS10365 dad9443dc29cb0aee3425b188d118a95 532 Pfam PF17203 Single cache domain 3 30 164 4.6E-31 T 06-07-2017 IPR033463 Single cache domain 3 GTHT12_RS10365 dad9443dc29cb0aee3425b188d118a95 532 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 317 361 1.8E-11 T 06-07-2017 GTHT12_RS10365 dad9443dc29cb0aee3425b188d118a95 532 Gene3D G3DSA:1.10.287.130 315 372 1.3E-22 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS10365 dad9443dc29cb0aee3425b188d118a95 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 486 504 3.3E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS10365 dad9443dc29cb0aee3425b188d118a95 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 470 3.3E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS10365 dad9443dc29cb0aee3425b188d118a95 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 510 523 3.3E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS10365 dad9443dc29cb0aee3425b188d118a95 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 474 484 3.3E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS04975 21422c8754379ae1d7c69dd54b7c0511 421 Pfam PF01547 Bacterial extracellular solute-binding protein 53 335 7.5E-46 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 GTHT12_RS04975 21422c8754379ae1d7c69dd54b7c0511 421 SUPERFAMILY SSF53850 43 415 3.02E-89 T 06-07-2017 GTHT12_RS04975 21422c8754379ae1d7c69dd54b7c0511 421 Gene3D G3DSA:3.40.190.10 43 172 2.4E-30 T 06-07-2017 GTHT12_RS04975 21422c8754379ae1d7c69dd54b7c0511 421 Gene3D G3DSA:3.40.190.10 173 352 7.2E-48 T 06-07-2017 GTHT12_RS09095 0d192cae6df727c7fb664cf4899372d7 300 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 63 81 2.8E-5 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS09095 0d192cae6df727c7fb664cf4899372d7 300 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 135 153 2.8E-5 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS09095 0d192cae6df727c7fb664cf4899372d7 300 SUPERFAMILY SSF52540 52 281 1.27E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS09095 0d192cae6df727c7fb664cf4899372d7 300 SMART SM00382 59 205 3.9E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS09095 0d192cae6df727c7fb664cf4899372d7 300 Gene3D G3DSA:3.40.50.300 47 216 2.0E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS09095 0d192cae6df727c7fb664cf4899372d7 300 Pfam PF07728 AAA domain (dynein-related subfamily) 62 199 2.3E-28 T 06-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 GTHT12_RS06485 ed2f56ff20ca1725746557fedda300be 294 SUPERFAMILY SSF54713 151 292 3.27E-54 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GTHT12_RS06485 ed2f56ff20ca1725746557fedda300be 294 Hamap MF_00050 Elongation factor Ts [tsf]. 1 291 84.839 T 06-07-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GTHT12_RS06485 ed2f56ff20ca1725746557fedda300be 294 Gene3D G3DSA:1.10.8.10 1 54 2.8E-31 T 06-07-2017 GTHT12_RS06485 ed2f56ff20ca1725746557fedda300be 294 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 06-07-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GTHT12_RS06485 ed2f56ff20ca1725746557fedda300be 294 SUPERFAMILY SSF46934 1 55 2.91E-22 T 06-07-2017 IPR009060 UBA-like GO:0005515 GTHT12_RS06485 ed2f56ff20ca1725746557fedda300be 294 Pfam PF00889 Elongation factor TS 70 274 1.9E-78 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GTHT12_RS06485 ed2f56ff20ca1725746557fedda300be 294 Gene3D G3DSA:1.10.286.20 194 237 2.0E-23 T 06-07-2017 GTHT12_RS06485 ed2f56ff20ca1725746557fedda300be 294 Gene3D G3DSA:3.30.479.20 152 189 3.3E-27 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GTHT12_RS06485 ed2f56ff20ca1725746557fedda300be 294 Gene3D G3DSA:3.30.479.20 238 273 3.3E-27 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GTHT12_RS06485 ed2f56ff20ca1725746557fedda300be 294 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 292 3.9E-118 T 06-07-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GTHT12_RS06485 ed2f56ff20ca1725746557fedda300be 294 SUPERFAMILY SSF54713 55 144 3.43E-23 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GTHT12_RS06485 ed2f56ff20ca1725746557fedda300be 294 Gene3D G3DSA:3.30.479.20 56 145 1.2E-21 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GTHT12_RS06485 ed2f56ff20ca1725746557fedda300be 294 ProSitePatterns PS01127 Elongation factor Ts signature 2. 74 84 - T 06-07-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GTHT12_RS17395 f3762a975cfbe386b1295edb7262a775 342 TIGRFAM TIGR02870 spore_II_D: stage II sporulation protein D 8 330 1.8E-130 T 06-07-2017 IPR014225 Sporulation stage II, protein D firmicutes GTHT12_RS17395 f3762a975cfbe386b1295edb7262a775 342 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 70 329 5.2E-80 T 06-07-2017 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 GTHT12_RS17395 f3762a975cfbe386b1295edb7262a775 342 Pfam PF08486 Stage II sporulation protein 67 170 6.9E-24 T 06-07-2017 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal GTHT12_RS04305 ff6bb4e460d606f4dfaa98c35dcff0ca 549 SUPERFAMILY SSF53850 39 547 5.79E-140 T 06-07-2017 GTHT12_RS04305 ff6bb4e460d606f4dfaa98c35dcff0ca 549 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 87 467 4.8E-90 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain GTHT12_RS04305 ff6bb4e460d606f4dfaa98c35dcff0ca 549 Gene3D G3DSA:3.10.105.10 301 519 4.3E-62 T 06-07-2017 GTHT12_RS04305 ff6bb4e460d606f4dfaa98c35dcff0ca 549 PIRSF PIRSF002741 1 549 1.1E-120 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 GTHT12_RS04305 ff6bb4e460d606f4dfaa98c35dcff0ca 549 Gene3D G3DSA:3.90.76.10 55 229 6.7E-56 T 06-07-2017 GTHT12_RS04305 ff6bb4e460d606f4dfaa98c35dcff0ca 549 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 93 115 - T 06-07-2017 IPR023765 Solute-binding protein family 5, conserved site GTHT12_RS01035 24a9301f88863eea87b06e3d802f4bf0 300 PIRSF PIRSF001111 1 295 1.9E-133 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 GTHT12_RS01035 24a9301f88863eea87b06e3d802f4bf0 300 Pfam PF00857 Isochorismatase family 32 205 1.3E-40 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 GTHT12_RS01035 24a9301f88863eea87b06e3d802f4bf0 300 SUPERFAMILY SSF47336 221 287 5.5E-9 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain GTHT12_RS01035 24a9301f88863eea87b06e3d802f4bf0 300 Gene3D G3DSA:3.40.50.850 1 227 4.1E-63 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 GTHT12_RS01035 24a9301f88863eea87b06e3d802f4bf0 300 Pfam PF00550 Phosphopantetheine attachment site 223 283 3.1E-7 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain GTHT12_RS01035 24a9301f88863eea87b06e3d802f4bf0 300 Gene3D G3DSA:1.10.1200.10 228 285 6.8E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain GTHT12_RS01035 24a9301f88863eea87b06e3d802f4bf0 300 SUPERFAMILY SSF52499 1 213 2.75E-65 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 GTHT12_RS01035 24a9301f88863eea87b06e3d802f4bf0 300 PRINTS PR01398 Isochorismatase signature 80 99 7.3E-49 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 GTHT12_RS01035 24a9301f88863eea87b06e3d802f4bf0 300 PRINTS PR01398 Isochorismatase signature 112 134 7.3E-49 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 GTHT12_RS01035 24a9301f88863eea87b06e3d802f4bf0 300 PRINTS PR01398 Isochorismatase signature 168 186 7.3E-49 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 GTHT12_RS01035 24a9301f88863eea87b06e3d802f4bf0 300 PRINTS PR01398 Isochorismatase signature 63 80 7.3E-49 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 GTHT12_RS01035 24a9301f88863eea87b06e3d802f4bf0 300 PRINTS PR01398 Isochorismatase signature 2 14 7.3E-49 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 GTHT12_RS01035 24a9301f88863eea87b06e3d802f4bf0 300 PRINTS PR01398 Isochorismatase signature 186 203 7.3E-49 T 06-07-2017 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 GTHT12_RS09585 58144a8160bac3759545f654d3fcd2aa 764 Gene3D G3DSA:3.40.50.920 269 409 3.0E-37 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GTHT12_RS09585 58144a8160bac3759545f654d3fcd2aa 764 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 31 255 6.2E-53 T 06-07-2017 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 GTHT12_RS09585 58144a8160bac3759545f654d3fcd2aa 764 SUPERFAMILY SSF52518 17 267 8.03E-55 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS09585 58144a8160bac3759545f654d3fcd2aa 764 Gene3D G3DSA:3.40.50.970 458 760 5.5E-54 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS09585 58144a8160bac3759545f654d3fcd2aa 764 SUPERFAMILY SSF52518 400 763 3.6E-58 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS09585 58144a8160bac3759545f654d3fcd2aa 764 Gene3D G3DSA:3.40.50.970 16 267 2.9E-67 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS09585 58144a8160bac3759545f654d3fcd2aa 764 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 278 382 3.1E-23 T 06-07-2017 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II GTHT12_RS09585 58144a8160bac3759545f654d3fcd2aa 764 SUPERFAMILY SSF52922 269 398 3.28E-29 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GTHT12_RS09585 58144a8160bac3759545f654d3fcd2aa 764 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 495 661 1.6E-10 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 GTHT12_RS17400 a7d397a8ca09148b03cfd07d4072f485 434 SUPERFAMILY SSF55205 2 419 1.57E-145 T 06-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 GTHT12_RS17400 a7d397a8ca09148b03cfd07d4072f485 434 Gene3D G3DSA:3.65.10.10 21 222 3.7E-68 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 GTHT12_RS17400 a7d397a8ca09148b03cfd07d4072f485 434 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 407 2.6E-116 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 GTHT12_RS17400 a7d397a8ca09148b03cfd07d4072f485 434 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 47.199 T 06-07-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS17400 a7d397a8ca09148b03cfd07d4072f485 434 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 416 1.9E-178 T 06-07-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS17400 a7d397a8ca09148b03cfd07d4072f485 434 Gene3D G3DSA:3.65.10.10 223 417 2.0E-63 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 GTHT12_RS18195 a70a0f5068357821035384d261124492 233 Pfam PF04474 Protein of unknown function (DUF554) 4 225 1.1E-76 T 06-07-2017 IPR007563 Protein of unknown function DUF554 GTHT12_RS07955 a86c94091305327464ab0a3200edaeaa 239 Pfam PF00665 Integrase core domain 79 192 1.0E-26 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS07955 a86c94091305327464ab0a3200edaeaa 239 Pfam PF13276 HTH-like domain 6 56 2.1E-16 T 06-07-2017 IPR025948 HTH-like domain GTHT12_RS07955 a86c94091305327464ab0a3200edaeaa 239 Gene3D G3DSA:3.30.420.10 73 230 2.6E-32 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS07955 a86c94091305327464ab0a3200edaeaa 239 SUPERFAMILY SSF53098 72 236 7.74E-39 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS10980 a86c94091305327464ab0a3200edaeaa 239 Pfam PF00665 Integrase core domain 79 192 1.0E-26 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS10980 a86c94091305327464ab0a3200edaeaa 239 Pfam PF13276 HTH-like domain 6 56 2.1E-16 T 06-07-2017 IPR025948 HTH-like domain GTHT12_RS10980 a86c94091305327464ab0a3200edaeaa 239 Gene3D G3DSA:3.30.420.10 73 230 2.6E-32 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS10980 a86c94091305327464ab0a3200edaeaa 239 SUPERFAMILY SSF53098 72 236 7.74E-39 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 Gene3D G3DSA:1.10.420.10 249 271 6.7E-51 T 06-07-2017 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 Gene3D G3DSA:1.10.420.10 307 406 6.7E-51 T 06-07-2017 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 SUPERFAMILY SSF48113 434 725 3.54E-113 T 06-07-2017 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 Pfam PF00141 Peroxidase 71 395 1.0E-52 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 Pfam PF00141 Peroxidase 401 700 6.9E-38 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 SUPERFAMILY SSF48113 22 428 3.09E-161 T 06-07-2017 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 ProSitePatterns PS00436 Peroxidases active site signature. 92 103 - T 06-07-2017 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 18 727 0.0 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 256 266 - T 06-07-2017 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 Hamap MF_01961 Catalase-peroxidase [katG]. 7 726 42.305 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 Gene3D G3DSA:1.10.420.10 581 701 3.9E-46 T 06-07-2017 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 28 50 8.6E-60 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 264 287 8.6E-60 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 54 67 8.6E-60 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 69 94 8.6E-60 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 478 504 8.6E-60 T 06-07-2017 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 Gene3D G3DSA:1.10.520.10 431 580 2.9E-62 T 06-07-2017 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 Gene3D G3DSA:1.10.520.10 49 203 8.5E-79 T 06-07-2017 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 Gene3D G3DSA:1.10.520.10 704 725 2.9E-62 T 06-07-2017 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 Gene3D G3DSA:1.10.520.10 236 248 8.5E-79 T 06-07-2017 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 PRINTS PR00458 Haem peroxidase superfamily signature 256 271 7.4E-21 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 PRINTS PR00458 Haem peroxidase superfamily signature 152 169 7.4E-21 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 PRINTS PR00458 Haem peroxidase superfamily signature 170 182 7.4E-21 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 PRINTS PR00458 Haem peroxidase superfamily signature 92 106 7.4E-21 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 GTHT12_RS08845 f41044a298fb3080b6626bd5812409d0 735 PRINTS PR00458 Haem peroxidase superfamily signature 315 330 7.4E-21 T 06-07-2017 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 GTHT12_RS08360 4c1fbf975aa53ee942c68f9a927ba1ca 367 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 5 362 3.1E-75 T 06-07-2017 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 GTHT12_RS08360 4c1fbf975aa53ee942c68f9a927ba1ca 367 Pfam PF03845 Spore germination protein 5 325 4.8E-80 T 06-07-2017 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 GTHT12_RS06480 6b4ac6767582705a5274dc6c63f2a88d 235 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 228 45.043 T 06-07-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 GTHT12_RS06480 6b4ac6767582705a5274dc6c63f2a88d 235 Pfam PF00318 Ribosomal protein S2 9 224 2.2E-105 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS06480 6b4ac6767582705a5274dc6c63f2a88d 235 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 06-07-2017 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 GTHT12_RS06480 6b4ac6767582705a5274dc6c63f2a88d 235 Gene3D G3DSA:3.40.50.10490 158 231 3.8E-73 T 06-07-2017 GTHT12_RS06480 6b4ac6767582705a5274dc6c63f2a88d 235 Gene3D G3DSA:3.40.50.10490 23 99 3.8E-73 T 06-07-2017 GTHT12_RS06480 6b4ac6767582705a5274dc6c63f2a88d 235 SUPERFAMILY SSF52313 6 229 5.1E-103 T 06-07-2017 IPR023591 Ribosomal protein S2, flavodoxin-like domain GTHT12_RS06480 6b4ac6767582705a5274dc6c63f2a88d 235 Gene3D G3DSA:1.10.287.610 100 152 3.7E-26 T 06-07-2017 GTHT12_RS06480 6b4ac6767582705a5274dc6c63f2a88d 235 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 3.9E-116 T 06-07-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 GTHT12_RS06480 6b4ac6767582705a5274dc6c63f2a88d 235 PRINTS PR00395 Ribosomal protein S2 signature 196 210 1.2E-42 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS06480 6b4ac6767582705a5274dc6c63f2a88d 235 PRINTS PR00395 Ribosomal protein S2 signature 6 24 1.2E-42 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS06480 6b4ac6767582705a5274dc6c63f2a88d 235 PRINTS PR00395 Ribosomal protein S2 signature 158 175 1.2E-42 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS06480 6b4ac6767582705a5274dc6c63f2a88d 235 PRINTS PR00395 Ribosomal protein S2 signature 37 46 1.2E-42 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS06480 6b4ac6767582705a5274dc6c63f2a88d 235 PRINTS PR00395 Ribosomal protein S2 signature 87 104 1.2E-42 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS06480 6b4ac6767582705a5274dc6c63f2a88d 235 PRINTS PR00395 Ribosomal protein S2 signature 175 186 1.2E-42 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS06480 6b4ac6767582705a5274dc6c63f2a88d 235 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 06-07-2017 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 GTHT12_RS08675 48e71ad01fc42ae8ba4cb949cd1c46e2 696 SMART SM00437 259 520 5.5E-83 T 06-07-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 GTHT12_RS08675 48e71ad01fc42ae8ba4cb949cd1c46e2 696 Gene3D G3DSA:2.70.20.10 350 460 6.9E-36 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 GTHT12_RS08675 48e71ad01fc42ae8ba4cb949cd1c46e2 696 SMART SM00436 125 215 6.2E-36 T 06-07-2017 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 GTHT12_RS08675 48e71ad01fc42ae8ba4cb949cd1c46e2 696 SUPERFAMILY SSF56712 1 594 5.23E-181 T 06-07-2017 IPR023405 DNA topoisomerase, type IA, core domain GTHT12_RS08675 48e71ad01fc42ae8ba4cb949cd1c46e2 696 Pfam PF01751 Toprim domain 4 131 1.1E-12 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS08675 48e71ad01fc42ae8ba4cb949cd1c46e2 696 Gene3D G3DSA:3.40.50.140 3 151 2.7E-48 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS08675 48e71ad01fc42ae8ba4cb949cd1c46e2 696 Gene3D G3DSA:1.10.460.10 155 208 7.7E-59 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 GTHT12_RS08675 48e71ad01fc42ae8ba4cb949cd1c46e2 696 Gene3D G3DSA:1.10.460.10 461 569 7.7E-59 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 GTHT12_RS08675 48e71ad01fc42ae8ba4cb949cd1c46e2 696 Pfam PF01131 DNA topoisomerase 152 554 7.4E-138 T 06-07-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 GTHT12_RS08675 48e71ad01fc42ae8ba4cb949cd1c46e2 696 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 671 1.0E-206 T 06-07-2017 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 GTHT12_RS08675 48e71ad01fc42ae8ba4cb949cd1c46e2 696 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 296 311 - T 06-07-2017 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 GTHT12_RS08675 48e71ad01fc42ae8ba4cb949cd1c46e2 696 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 483 497 9.0E-30 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS08675 48e71ad01fc42ae8ba4cb949cd1c46e2 696 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 9.0E-30 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS08675 48e71ad01fc42ae8ba4cb949cd1c46e2 696 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 185 203 9.0E-30 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS08675 48e71ad01fc42ae8ba4cb949cd1c46e2 696 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 302 311 9.0E-30 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS08675 48e71ad01fc42ae8ba4cb949cd1c46e2 696 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 384 400 9.0E-30 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS08675 48e71ad01fc42ae8ba4cb949cd1c46e2 696 Gene3D G3DSA:2.70.20.10 209 319 7.3E-24 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 GTHT12_RS08675 48e71ad01fc42ae8ba4cb949cd1c46e2 696 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 623 651 2.7 T 06-07-2017 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 GTHT12_RS08675 48e71ad01fc42ae8ba4cb949cd1c46e2 696 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 584 617 8.5E-6 T 06-07-2017 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 GTHT12_RS08675 48e71ad01fc42ae8ba4cb949cd1c46e2 696 SMART SM00493 2 125 3.3E-18 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS11380 34854a3b79033fb8b8a91cb642658f58 340 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 5.4E-17 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS11380 34854a3b79033fb8b8a91cb642658f58 340 SUPERFAMILY SSF53822 63 325 1.99E-52 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS11380 34854a3b79033fb8b8a91cb642658f58 340 Gene3D G3DSA:3.40.50.2300 74 164 1.6E-7 T 06-07-2017 GTHT12_RS11380 34854a3b79033fb8b8a91cb642658f58 340 Pfam PF13377 Periplasmic binding protein-like domain 168 331 1.3E-39 T 06-07-2017 GTHT12_RS11380 34854a3b79033fb8b8a91cb642658f58 340 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 06-07-2017 GTHT12_RS11380 34854a3b79033fb8b8a91cb642658f58 340 SMART SM00354 1 72 3.0E-14 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS11380 34854a3b79033fb8b8a91cb642658f58 340 SUPERFAMILY SSF47413 3 48 5.34E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS11380 34854a3b79033fb8b8a91cb642658f58 340 Gene3D G3DSA:3.40.50.2300 165 331 3.9E-53 T 06-07-2017 GTHT12_RS11380 34854a3b79033fb8b8a91cb642658f58 340 Gene3D G3DSA:1.10.260.40 1 48 5.7E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS11380 34854a3b79033fb8b8a91cb642658f58 340 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 4.3E-5 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS11380 34854a3b79033fb8b8a91cb642658f58 340 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 4.3E-5 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS09295 d8f70f6d0ee872edec82ba6ae4327eeb 454 SUPERFAMILY SSF53335 2 301 1.84E-68 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS09295 d8f70f6d0ee872edec82ba6ae4327eeb 454 Pfam PF01189 16S rRNA methyltransferase RsmB/F 96 300 1.8E-55 T 06-07-2017 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS09295 d8f70f6d0ee872edec82ba6ae4327eeb 454 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 172 183 - T 06-07-2017 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS09295 d8f70f6d0ee872edec82ba6ae4327eeb 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 284 301 1.3E-28 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS09295 d8f70f6d0ee872edec82ba6ae4327eeb 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 106 116 1.3E-28 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS09295 d8f70f6d0ee872edec82ba6ae4327eeb 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 77 91 1.3E-28 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS09295 d8f70f6d0ee872edec82ba6ae4327eeb 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 173 185 1.3E-28 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS09295 d8f70f6d0ee872edec82ba6ae4327eeb 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 223 239 1.3E-28 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS09295 d8f70f6d0ee872edec82ba6ae4327eeb 454 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 34 301 1.1E-71 T 06-07-2017 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901 GTHT12_RS09295 d8f70f6d0ee872edec82ba6ae4327eeb 454 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 407 452 1.6E-17 T 06-07-2017 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS09295 d8f70f6d0ee872edec82ba6ae4327eeb 454 Gene3D G3DSA:3.40.50.150 89 301 4.3E-63 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS09295 d8f70f6d0ee872edec82ba6ae4327eeb 454 Pfam PF17126 RsmF rRNA methyltransferase first C-terminal domain 328 388 2.9E-23 T 06-07-2017 IPR031340 Ribosomal RNA small subunit methyltransferase F, first C-terminal domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS09295 d8f70f6d0ee872edec82ba6ae4327eeb 454 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 3 91 2.6E-35 T 06-07-2017 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901 GTHT12_RS18755 f81d5b1b2ebd9174d5c55a0b0b72986d 251 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 188 202 3.9E-5 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS18755 f81d5b1b2ebd9174d5c55a0b0b72986d 251 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 101 119 3.9E-5 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS18755 f81d5b1b2ebd9174d5c55a0b0b72986d 251 SMART SM00382 97 229 7.9E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS18755 f81d5b1b2ebd9174d5c55a0b0b72986d 251 Gene3D G3DSA:3.40.50.300 64 228 1.6E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18755 f81d5b1b2ebd9174d5c55a0b0b72986d 251 Pfam PF01695 IstB-like ATP binding protein 53 228 2.9E-72 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 GTHT12_RS18755 f81d5b1b2ebd9174d5c55a0b0b72986d 251 PIRSF PIRSF003073 1 251 1.4E-87 T 06-07-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein GTHT12_RS18755 f81d5b1b2ebd9174d5c55a0b0b72986d 251 SUPERFAMILY SSF52540 64 225 6.86E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05235 f81d5b1b2ebd9174d5c55a0b0b72986d 251 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 188 202 3.9E-5 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS05235 f81d5b1b2ebd9174d5c55a0b0b72986d 251 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 101 119 3.9E-5 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS05235 f81d5b1b2ebd9174d5c55a0b0b72986d 251 SMART SM00382 97 229 7.9E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS05235 f81d5b1b2ebd9174d5c55a0b0b72986d 251 Gene3D G3DSA:3.40.50.300 64 228 1.6E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05235 f81d5b1b2ebd9174d5c55a0b0b72986d 251 Pfam PF01695 IstB-like ATP binding protein 53 228 2.9E-72 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 GTHT12_RS05235 f81d5b1b2ebd9174d5c55a0b0b72986d 251 PIRSF PIRSF003073 1 251 1.4E-87 T 06-07-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein GTHT12_RS05235 f81d5b1b2ebd9174d5c55a0b0b72986d 251 SUPERFAMILY SSF52540 64 225 6.86E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS04655 f81d5b1b2ebd9174d5c55a0b0b72986d 251 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 188 202 3.9E-5 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS04655 f81d5b1b2ebd9174d5c55a0b0b72986d 251 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 101 119 3.9E-5 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS04655 f81d5b1b2ebd9174d5c55a0b0b72986d 251 SMART SM00382 97 229 7.9E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS04655 f81d5b1b2ebd9174d5c55a0b0b72986d 251 Gene3D G3DSA:3.40.50.300 64 228 1.6E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS04655 f81d5b1b2ebd9174d5c55a0b0b72986d 251 Pfam PF01695 IstB-like ATP binding protein 53 228 2.9E-72 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 GTHT12_RS04655 f81d5b1b2ebd9174d5c55a0b0b72986d 251 PIRSF PIRSF003073 1 251 1.4E-87 T 06-07-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein GTHT12_RS04655 f81d5b1b2ebd9174d5c55a0b0b72986d 251 SUPERFAMILY SSF52540 64 225 6.86E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS15620 1b6009078e6a22c04cba5be96593688a 222 SUPERFAMILY SSF161098 11 209 9.16E-47 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS15620 1b6009078e6a22c04cba5be96593688a 222 Gene3D G3DSA:1.10.3720.10 11 221 3.5E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS15620 1b6009078e6a22c04cba5be96593688a 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 39 222 1.7E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS17830 9766ba4e71f5b15c615b2189ee649e6e 635 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 259 387 1.1E-13 T 06-07-2017 IPR000014 PAS domain GTHT12_RS17830 9766ba4e71f5b15c615b2189ee649e6e 635 SUPERFAMILY SSF81606 432 633 3.79E-8 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 GTHT12_RS17830 9766ba4e71f5b15c615b2189ee649e6e 635 Pfam PF13426 PAS domain 273 381 1.9E-11 T 06-07-2017 IPR000014 PAS domain GTHT12_RS17830 9766ba4e71f5b15c615b2189ee649e6e 635 Gene3D G3DSA:3.30.450.20 256 380 8.2E-20 T 06-07-2017 GTHT12_RS17830 9766ba4e71f5b15c615b2189ee649e6e 635 Pfam PF17159 Membrane-associated sensor domain 39 253 1.5E-32 T 06-07-2017 IPR033425 Membrane-associated sensor domain MASE3 GTHT12_RS17830 9766ba4e71f5b15c615b2189ee649e6e 635 SMART SM00091 262 328 8.2E-8 T 06-07-2017 IPR000014 PAS domain GTHT12_RS17830 9766ba4e71f5b15c615b2189ee649e6e 635 Gene3D G3DSA:3.60.40.10 547 632 2.1E-4 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 GTHT12_RS17830 9766ba4e71f5b15c615b2189ee649e6e 635 SMART SM00331 419 634 1.6E-40 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 GTHT12_RS17830 9766ba4e71f5b15c615b2189ee649e6e 635 SUPERFAMILY SSF55785 255 380 1.15E-17 T 06-07-2017 IPR000014 PAS domain GTHT12_RS17830 9766ba4e71f5b15c615b2189ee649e6e 635 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 447 634 1.3E-44 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 GTHT12_RS18635 6d6044162322ca97107c2c7127887e9a 265 Gene3D G3DSA:3.40.50.300 4 263 2.1E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18635 6d6044162322ca97107c2c7127887e9a 265 SUPERFAMILY SSF52540 4 262 6.67E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18635 6d6044162322ca97107c2c7127887e9a 265 Pfam PF13614 AAA domain 4 180 6.9E-35 T 06-07-2017 IPR025669 AAA domain GTHT12_RS13265 4315909dee187459f3c58e17baa561c8 341 Pfam PF01594 Domain of unknown function DUF20 5 332 1.4E-59 T 06-07-2017 IPR002549 Transmembrane protein TqsA-like GTHT12_RS13265 4315909dee187459f3c58e17baa561c8 341 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 6 335 1.3E-113 T 06-07-2017 IPR014227 Sporulation integral membrane protein YtvI GTHT12_RS11625 ec957dff36e1a6f01e03d0c7f01a75e7 365 Gene3D G3DSA:3.90.1150.10 262 361 2.9E-23 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS11625 ec957dff36e1a6f01e03d0c7f01a75e7 365 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 5 356 7.8E-117 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 GTHT12_RS11625 ec957dff36e1a6f01e03d0c7f01a75e7 365 SUPERFAMILY SSF53383 12 357 3.86E-87 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS11625 ec957dff36e1a6f01e03d0c7f01a75e7 365 Pfam PF00155 Aminotransferase class I and II 30 355 2.6E-65 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 GTHT12_RS11625 ec957dff36e1a6f01e03d0c7f01a75e7 365 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 359 64.33 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 GTHT12_RS11625 ec957dff36e1a6f01e03d0c7f01a75e7 365 Gene3D G3DSA:3.40.640.10 44 261 4.1E-71 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS11625 ec957dff36e1a6f01e03d0c7f01a75e7 365 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 219 228 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 GTHT12_RS00625 9ead2b2d6c75cdfdfaf87907f7b3f955 1199 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 331 2.9E-90 T 06-07-2017 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00625 9ead2b2d6c75cdfdfaf87907f7b3f955 1199 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 384 2.7E-9 T 06-07-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00625 9ead2b2d6c75cdfdfaf87907f7b3f955 1199 Pfam PF00623 RNA polymerase Rpb1, domain 2 379 474 1.1E-29 T 06-07-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00625 9ead2b2d6c75cdfdfaf87907f7b3f955 1199 Gene3D G3DSA:2.40.40.20 338 365 3.0E-38 T 06-07-2017 GTHT12_RS00625 9ead2b2d6c75cdfdfaf87907f7b3f955 1199 Gene3D G3DSA:2.40.40.20 406 477 3.0E-38 T 06-07-2017 GTHT12_RS00625 9ead2b2d6c75cdfdfaf87907f7b3f955 1199 Gene3D G3DSA:2.40.50.100 970 1026 2.4E-10 T 06-07-2017 GTHT12_RS00625 9ead2b2d6c75cdfdfaf87907f7b3f955 1199 Hamap MF_01323 DNA-directed RNA polymerase subunit gamma [rpoC1]. 3 576 32.887 T 06-07-2017 GTHT12_RS00625 9ead2b2d6c75cdfdfaf87907f7b3f955 1199 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1181 0.0 T 06-07-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00625 9ead2b2d6c75cdfdfaf87907f7b3f955 1199 SUPERFAMILY SSF64484 5 1183 0.0 T 06-07-2017 GTHT12_RS00625 9ead2b2d6c75cdfdfaf87907f7b3f955 1199 SMART SM00663 224 503 2.3E-184 T 06-07-2017 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00625 9ead2b2d6c75cdfdfaf87907f7b3f955 1199 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 5 1190 10.463 T 06-07-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00625 9ead2b2d6c75cdfdfaf87907f7b3f955 1199 Pfam PF05000 RNA polymerase Rpb1, domain 4 692 759 6.7E-15 T 06-07-2017 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00625 9ead2b2d6c75cdfdfaf87907f7b3f955 1199 Pfam PF04998 RNA polymerase Rpb1, domain 5 770 988 3.1E-51 T 06-07-2017 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00625 9ead2b2d6c75cdfdfaf87907f7b3f955 1199 Pfam PF04998 RNA polymerase Rpb1, domain 5 1005 1129 1.0E-14 T 06-07-2017 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00625 9ead2b2d6c75cdfdfaf87907f7b3f955 1199 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 663 2.7E-36 T 06-07-2017 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS17095 d4e9113f9c8883fa69f648cce5ffdfc7 202 SUPERFAMILY SSF51283 3 191 3.01E-31 T 06-07-2017 IPR029054 dUTPase-like GTHT12_RS17095 d4e9113f9c8883fa69f648cce5ffdfc7 202 Pfam PF00692 dUTPase 80 162 3.2E-11 T 06-07-2017 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 GTHT12_RS17095 d4e9113f9c8883fa69f648cce5ffdfc7 202 Gene3D G3DSA:2.70.40.10 3 191 3.5E-36 T 06-07-2017 IPR029054 dUTPase-like GTHT12_RS17095 d4e9113f9c8883fa69f648cce5ffdfc7 202 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 188 2.1E-37 T 06-07-2017 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 GTHT12_RS09440 2c17b49c8dd0ea2f022b8eed68d60e48 372 Gene3D G3DSA:3.30.2110.10 9 181 6.3E-61 T 06-07-2017 GTHT12_RS09440 2c17b49c8dd0ea2f022b8eed68d60e48 372 SUPERFAMILY SSF111342 3 285 6.93E-89 T 06-07-2017 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 GTHT12_RS09440 2c17b49c8dd0ea2f022b8eed68d60e48 372 Pfam PF01888 CbiD 7 267 2.8E-99 T 06-07-2017 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 GTHT12_RS09440 2c17b49c8dd0ea2f022b8eed68d60e48 372 PIRSF PIRSF026782 3 364 7.0E-128 T 06-07-2017 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 GTHT12_RS09440 2c17b49c8dd0ea2f022b8eed68d60e48 372 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 7 358 29.764 T 06-07-2017 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 GTHT12_RS09440 2c17b49c8dd0ea2f022b8eed68d60e48 372 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 14 354 7.3E-67 T 06-07-2017 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 GTHT12_RS13605 86e7f665ffb56f5249e8a25ce97b491c 282 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 227 234 - T 06-07-2017 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 GTHT12_RS13605 86e7f665ffb56f5249e8a25ce97b491c 282 Pfam PF01842 ACT domain 200 254 9.8E-8 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 GTHT12_RS13605 86e7f665ffb56f5249e8a25ce97b491c 282 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 158 180 - T 06-07-2017 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 GTHT12_RS13605 86e7f665ffb56f5249e8a25ce97b491c 282 SUPERFAMILY SSF53850 1 189 4.78E-55 T 06-07-2017 GTHT12_RS13605 86e7f665ffb56f5249e8a25ce97b491c 282 Pfam PF00800 Prephenate dehydratase 3 183 2.0E-56 T 06-07-2017 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 GTHT12_RS13605 86e7f665ffb56f5249e8a25ce97b491c 282 Gene3D G3DSA:3.40.190.10 88 170 1.8E-27 T 06-07-2017 GTHT12_RS13605 86e7f665ffb56f5249e8a25ce97b491c 282 Gene3D G3DSA:3.40.190.10 1 87 3.6E-26 T 06-07-2017 GTHT12_RS13605 86e7f665ffb56f5249e8a25ce97b491c 282 PIRSF PIRSF001500 1 282 2.1E-70 T 06-07-2017 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 GTHT12_RS13605 86e7f665ffb56f5249e8a25ce97b491c 282 SUPERFAMILY SSF55021 191 279 7.75E-25 T 06-07-2017 GTHT12_RS13605 86e7f665ffb56f5249e8a25ce97b491c 282 Gene3D G3DSA:3.30.70.260 196 279 1.6E-26 T 06-07-2017 GTHT12_RS13545 368e474078f901264de592e484d1bda6 194 Pfam PF14520 Helix-hairpin-helix domain 71 128 1.8E-14 T 06-07-2017 GTHT12_RS13545 368e474078f901264de592e484d1bda6 194 Gene3D G3DSA:1.10.8.10 150 192 1.1E-12 T 06-07-2017 GTHT12_RS13545 368e474078f901264de592e484d1bda6 194 SMART SM00278 107 126 3.0 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 GTHT12_RS13545 368e474078f901264de592e484d1bda6 194 SMART SM00278 72 91 4.3 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 GTHT12_RS13545 368e474078f901264de592e484d1bda6 194 SUPERFAMILY SSF47781 64 132 9.45E-20 T 06-07-2017 IPR010994 RuvA domain 2-like GTHT12_RS13545 368e474078f901264de592e484d1bda6 194 Pfam PF07499 RuvA, C-terminal domain 150 191 2.5E-11 T 06-07-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 GTHT12_RS13545 368e474078f901264de592e484d1bda6 194 SUPERFAMILY SSF50249 1 62 1.03E-15 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS13545 368e474078f901264de592e484d1bda6 194 Gene3D G3DSA:1.10.150.20 66 135 3.8E-28 T 06-07-2017 GTHT12_RS13545 368e474078f901264de592e484d1bda6 194 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 193 2.9E-57 T 06-07-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 GTHT12_RS13545 368e474078f901264de592e484d1bda6 194 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 193 29.643 T 06-07-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 GTHT12_RS13545 368e474078f901264de592e484d1bda6 194 SUPERFAMILY SSF46929 149 192 1.57E-9 T 06-07-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 GTHT12_RS13545 368e474078f901264de592e484d1bda6 194 Pfam PF01330 RuvA N terminal domain 2 61 8.2E-19 T 06-07-2017 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 GTHT12_RS13545 368e474078f901264de592e484d1bda6 194 Gene3D G3DSA:2.40.50.140 2 65 1.1E-20 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS18115 e632e0d94fa02179e38e37ba3a0145a3 442 Pfam PF07435 YycH protein 3 428 2.5E-92 T 06-07-2017 IPR009996 Regulatory protein YycH GTHT12_RS16140 155bc6878c4cc14426768750586a4834 133 Gene3D G3DSA:1.20.120.340 3 125 5.4E-44 T 06-07-2017 IPR003713 Flagellar protein FliS GO:0044780 GTHT12_RS16140 155bc6878c4cc14426768750586a4834 133 TIGRFAM TIGR00208 fliS: flagellar protein FliS 1 120 1.1E-42 T 06-07-2017 IPR003713 Flagellar protein FliS GO:0044780 GTHT12_RS16140 155bc6878c4cc14426768750586a4834 133 SUPERFAMILY SSF101116 4 123 1.29E-39 T 06-07-2017 IPR003713 Flagellar protein FliS GO:0044780 GTHT12_RS16140 155bc6878c4cc14426768750586a4834 133 Pfam PF02561 Flagellar protein FliS 7 118 2.7E-41 T 06-07-2017 IPR003713 Flagellar protein FliS GO:0044780 GTHT12_RS16140 155bc6878c4cc14426768750586a4834 133 PIRSF PIRSF039090 1 129 6.2E-37 T 06-07-2017 IPR003713 Flagellar protein FliS GO:0044780 GTHT12_RS05435 0a9f96b34c0d5d8ed83912aee58d163e 352 Gene3D G3DSA:3.90.1200.10 131 348 2.1E-46 T 06-07-2017 GTHT12_RS05435 0a9f96b34c0d5d8ed83912aee58d163e 352 Pfam PF01636 Phosphotransferase enzyme family 35 267 2.1E-39 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase GTHT12_RS05435 0a9f96b34c0d5d8ed83912aee58d163e 352 SUPERFAMILY SSF56112 13 348 2.25E-62 T 06-07-2017 IPR011009 Protein kinase-like domain GTHT12_RS14745 6a4a0d4f8afadc725618b7dcc2cd3e13 399 Pfam PF07690 Major Facilitator Superfamily 228 393 2.1E-20 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS14745 6a4a0d4f8afadc725618b7dcc2cd3e13 399 Pfam PF07690 Major Facilitator Superfamily 8 227 8.1E-20 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS14745 6a4a0d4f8afadc725618b7dcc2cd3e13 399 Gene3D G3DSA:1.20.1250.20 204 382 1.4E-28 T 06-07-2017 GTHT12_RS14745 6a4a0d4f8afadc725618b7dcc2cd3e13 399 Gene3D G3DSA:1.20.1250.20 3 179 5.6E-23 T 06-07-2017 GTHT12_RS14745 6a4a0d4f8afadc725618b7dcc2cd3e13 399 SUPERFAMILY SSF103473 3 386 5.49E-60 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS06250 08ed0bd024aecc99dfb7818282b387e4 183 Pfam PF00717 Peptidase S24-like 35 102 2.8E-19 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B GTHT12_RS06250 08ed0bd024aecc99dfb7818282b387e4 183 Gene3D G3DSA:2.10.109.10 136 179 5.4E-40 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain GTHT12_RS06250 08ed0bd024aecc99dfb7818282b387e4 183 Gene3D G3DSA:2.10.109.10 25 88 5.4E-40 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain GTHT12_RS06250 08ed0bd024aecc99dfb7818282b387e4 183 ProSitePatterns PS00501 Signal peptidases I serine active site. 37 44 - T 06-07-2017 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 GTHT12_RS06250 08ed0bd024aecc99dfb7818282b387e4 183 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 11 176 3.4E-57 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 GTHT12_RS06250 08ed0bd024aecc99dfb7818282b387e4 183 ProSitePatterns PS00761 Signal peptidases I signature 3. 141 154 - T 06-07-2017 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 GTHT12_RS06250 08ed0bd024aecc99dfb7818282b387e4 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 136 155 1.1E-21 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 GTHT12_RS06250 08ed0bd024aecc99dfb7818282b387e4 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 28 44 1.1E-21 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 GTHT12_RS06250 08ed0bd024aecc99dfb7818282b387e4 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 78 90 1.1E-21 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 GTHT12_RS06250 08ed0bd024aecc99dfb7818282b387e4 183 SUPERFAMILY SSF51306 26 180 1.38E-55 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C GTHT12_RS06250 08ed0bd024aecc99dfb7818282b387e4 183 ProSitePatterns PS00760 Signal peptidases I lysine active site. 80 92 - T 06-07-2017 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 GTHT12_RS08910 5b1ce5624b6e88d9bc802a7561cc68ab 67 Pfam PF01381 Helix-turn-helix 5 59 3.2E-17 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GTHT12_RS08910 5b1ce5624b6e88d9bc802a7561cc68ab 67 Gene3D G3DSA:1.10.260.40 2 63 2.3E-25 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS08910 5b1ce5624b6e88d9bc802a7561cc68ab 67 SUPERFAMILY SSF47413 2 63 5.09E-20 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS08910 5b1ce5624b6e88d9bc802a7561cc68ab 67 SMART SM00530 4 59 1.2E-16 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GTHT12_RS02430 b514f72e08fbc5b0dab20b774b12e731 115 Gene3D G3DSA:2.70.180.10 1 114 2.1E-54 T 06-07-2017 IPR014934 Protein of unknown function DUF1806 GTHT12_RS02430 b514f72e08fbc5b0dab20b774b12e731 115 Pfam PF08830 Protein of unknown function (DUF1806) 3 114 2.4E-53 T 06-07-2017 IPR014934 Protein of unknown function DUF1806 GTHT12_RS02430 b514f72e08fbc5b0dab20b774b12e731 115 SUPERFAMILY SSF89442 1 114 1.7E-55 T 06-07-2017 IPR014934 Protein of unknown function DUF1806 GTHT12_RS00215 a383b261f208cb708812e4c5c9006235 410 SUPERFAMILY SSF50685 350 396 3.84E-7 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain GTHT12_RS00215 a383b261f208cb708812e4c5c9006235 410 Pfam PF07501 G5 domain 214 286 5.2E-21 T 06-07-2017 IPR011098 G5 domain GTHT12_RS00215 a383b261f208cb708812e4c5c9006235 410 Pfam PF06725 3D domain 349 409 3.4E-19 T 06-07-2017 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 GTHT12_RS00215 a383b261f208cb708812e4c5c9006235 410 Pfam PF03990 Domain of unknown function (DUF348) 99 139 7.3E-16 T 06-07-2017 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 GTHT12_RS00215 a383b261f208cb708812e4c5c9006235 410 Pfam PF03990 Domain of unknown function (DUF348) 42 82 2.2E-14 T 06-07-2017 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 GTHT12_RS00215 a383b261f208cb708812e4c5c9006235 410 Pfam PF03990 Domain of unknown function (DUF348) 156 195 5.8E-15 T 06-07-2017 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 GTHT12_RS00215 a383b261f208cb708812e4c5c9006235 410 SMART SM01208 209 287 8.5E-27 T 06-07-2017 IPR011098 G5 domain GTHT12_RS16045 9e7aa8ac689663d648e346d3f26f883a 955 Hamap MF_00205 UvrABC system protein A [uvrA]. 4 939 23.834 T 06-07-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 GTHT12_RS16045 9e7aa8ac689663d648e346d3f26f883a 955 Gene3D G3DSA:1.20.1580.10 94 132 2.8E-56 T 06-07-2017 GTHT12_RS16045 9e7aa8ac689663d648e346d3f26f883a 955 Gene3D G3DSA:1.20.1580.10 251 284 2.8E-56 T 06-07-2017 GTHT12_RS16045 9e7aa8ac689663d648e346d3f26f883a 955 Gene3D G3DSA:1.20.1580.10 408 478 2.8E-56 T 06-07-2017 GTHT12_RS16045 9e7aa8ac689663d648e346d3f26f883a 955 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 6 924 0.0 T 06-07-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 GTHT12_RS16045 9e7aa8ac689663d648e346d3f26f883a 955 SUPERFAMILY SSF52540 616 909 9.97E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16045 9e7aa8ac689663d648e346d3f26f883a 955 Gene3D G3DSA:3.40.50.300 608 691 4.4E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16045 9e7aa8ac689663d648e346d3f26f883a 955 Gene3D G3DSA:3.40.50.300 479 596 6.1E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16045 9e7aa8ac689663d648e346d3f26f883a 955 Gene3D G3DSA:3.40.50.300 820 942 4.4E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16045 9e7aa8ac689663d648e346d3f26f883a 955 Gene3D G3DSA:3.40.50.300 7 92 6.1E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16045 9e7aa8ac689663d648e346d3f26f883a 955 ProSitePatterns PS00211 ABC transporters family signature. 488 502 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS16045 9e7aa8ac689663d648e346d3f26f883a 955 Gene3D G3DSA:1.20.1580.10 693 819 1.5E-56 T 06-07-2017 GTHT12_RS16045 9e7aa8ac689663d648e346d3f26f883a 955 Pfam PF00005 ABC transporter 623 859 5.2E-11 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS16045 9e7aa8ac689663d648e346d3f26f883a 955 SMART SM00382 632 954 0.0018 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS16045 9e7aa8ac689663d648e346d3f26f883a 955 SMART SM00382 26 565 11.0 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS16045 9e7aa8ac689663d648e346d3f26f883a 955 SUPERFAMILY SSF52540 14 207 2.79E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16045 9e7aa8ac689663d648e346d3f26f883a 955 SUPERFAMILY SSF52540 431 570 2.79E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16045 9e7aa8ac689663d648e346d3f26f883a 955 Gene3D G3DSA:1.10.8.280 286 407 1.6E-47 T 06-07-2017 GTHT12_RS16045 9e7aa8ac689663d648e346d3f26f883a 955 Gene3D G3DSA:3.30.1490.20 133 156 1.1E-29 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GTHT12_RS16045 9e7aa8ac689663d648e346d3f26f883a 955 Gene3D G3DSA:3.30.1490.20 203 250 1.1E-29 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GTHT12_RS16045 9e7aa8ac689663d648e346d3f26f883a 955 ProSitePatterns PS00211 ABC transporters family signature. 829 843 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS10015 0cef2169148aa9a79a65719e1bded011 400 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 376 392 1.0E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 GTHT12_RS10015 0cef2169148aa9a79a65719e1bded011 400 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 361 376 1.0E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 GTHT12_RS10015 0cef2169148aa9a79a65719e1bded011 400 SUPERFAMILY SSF46689 345 395 3.14E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS10015 0cef2169148aa9a79a65719e1bded011 400 Pfam PF00072 Response regulator receiver domain 4 116 1.9E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS10015 0cef2169148aa9a79a65719e1bded011 400 SMART SM00342 309 392 1.4E-32 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 GTHT12_RS10015 0cef2169148aa9a79a65719e1bded011 400 Pfam PF12833 Helix-turn-helix domain 316 393 9.4E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 GTHT12_RS10015 0cef2169148aa9a79a65719e1bded011 400 SUPERFAMILY SSF46689 292 340 2.99E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS10015 0cef2169148aa9a79a65719e1bded011 400 Gene3D G3DSA:3.40.50.2300 2 128 1.6E-36 T 06-07-2017 GTHT12_RS10015 0cef2169148aa9a79a65719e1bded011 400 SMART SM00448 2 116 5.5E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS10015 0cef2169148aa9a79a65719e1bded011 400 Gene3D G3DSA:1.10.10.60 347 395 7.2E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS10015 0cef2169148aa9a79a65719e1bded011 400 SUPERFAMILY SSF52172 1 150 6.97E-36 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS10015 0cef2169148aa9a79a65719e1bded011 400 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 346 388 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 GTHT12_RS10015 0cef2169148aa9a79a65719e1bded011 400 Gene3D G3DSA:1.10.10.60 288 346 6.5E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS13880 614eb6484ffcbb760324f7794a7b7f53 341 SUPERFAMILY SSF48179 183 330 1.11E-71 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GTHT12_RS13880 614eb6484ffcbb760324f7794a7b7f53 341 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 177 1.2E-79 T 06-07-2017 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 GTHT12_RS13880 614eb6484ffcbb760324f7794a7b7f53 341 Gene3D G3DSA:1.10.1040.10 40 325 5.1E-118 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 GTHT12_RS13880 614eb6484ffcbb760324f7794a7b7f53 341 Gene3D G3DSA:3.50.50.60 6 39 5.3E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS13880 614eb6484ffcbb760324f7794a7b7f53 341 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 2 328 45.663 T 06-07-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 GTHT12_RS13880 614eb6484ffcbb760324f7794a7b7f53 341 SUPERFAMILY SSF51735 3 182 1.16E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS13880 614eb6484ffcbb760324f7794a7b7f53 341 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 327 5.5E-148 T 06-07-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 GTHT12_RS13880 614eb6484ffcbb760324f7794a7b7f53 341 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 325 1.8E-67 T 06-07-2017 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 GTHT12_RS06490 342a4873e7cbcd392c0d7f8b68242f5c 240 Pfam PF00696 Amino acid kinase family 7 217 3.2E-28 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase GTHT12_RS06490 342a4873e7cbcd392c0d7f8b68242f5c 240 SUPERFAMILY SSF53633 4 238 2.23E-75 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase GTHT12_RS06490 342a4873e7cbcd392c0d7f8b68242f5c 240 PIRSF PIRSF005650 1 240 1.8E-99 T 06-07-2017 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 GTHT12_RS06490 342a4873e7cbcd392c0d7f8b68242f5c 240 Gene3D G3DSA:3.40.1160.10 2 237 2.9E-91 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase GTHT12_RS06490 342a4873e7cbcd392c0d7f8b68242f5c 240 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 238 45.511 T 06-07-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 GTHT12_RS06490 342a4873e7cbcd392c0d7f8b68242f5c 240 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 4.4E-104 T 06-07-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 GTHT12_RS07565 dd99c4ed1284264f761edbdfc43bdc9e 245 Pfam PF06276 Ferric iron reductase FhuF-like transporter 69 211 1.9E-10 T 06-07-2017 IPR022770 Ferric iron reductase FhuF domain GTHT12_RS10935 a6bc2179258ff5513f3c63f77a5b2c19 378 SUPERFAMILY SSF52821 2 106 9.17E-22 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS10935 a6bc2179258ff5513f3c63f77a5b2c19 378 SUPERFAMILY SSF56281 122 320 1.35E-43 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS10935 a6bc2179258ff5513f3c63f77a5b2c19 378 Pfam PF00581 Rhodanese-like domain 15 105 1.9E-12 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS10935 a6bc2179258ff5513f3c63f77a5b2c19 378 SMART SM00450 6 109 2.0E-16 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS10935 a6bc2179258ff5513f3c63f77a5b2c19 378 Gene3D G3DSA:3.40.250.10 2 106 8.0E-23 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS10935 a6bc2179258ff5513f3c63f77a5b2c19 378 Pfam PF00753 Metallo-beta-lactamase superfamily 129 290 1.0E-16 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS10935 a6bc2179258ff5513f3c63f77a5b2c19 378 Gene3D G3DSA:3.60.15.10 120 351 3.9E-48 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS10935 a6bc2179258ff5513f3c63f77a5b2c19 378 SMART SM00849 129 291 1.3E-26 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS14185 9f2363aae7c043796f2fe8e5d9b956e0 124 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 1 116 31.579 T 06-07-2017 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 GTHT12_RS14185 9f2363aae7c043796f2fe8e5d9b956e0 124 Pfam PF02675 S-adenosylmethionine decarboxylase 7 112 1.8E-37 T 06-07-2017 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 GTHT12_RS14185 9f2363aae7c043796f2fe8e5d9b956e0 124 SUPERFAMILY SSF56276 3 113 4.12E-41 T 06-07-2017 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 GTHT12_RS14185 9f2363aae7c043796f2fe8e5d9b956e0 124 Gene3D G3DSA:3.60.90.10 1 120 1.0E-45 T 06-07-2017 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 GTHT12_RS14185 9f2363aae7c043796f2fe8e5d9b956e0 124 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 3 112 1.9E-42 T 06-07-2017 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 GTHT12_RS08090 93adce25961631370573718acfa9b348 332 Gene3D G3DSA:3.20.20.70 16 322 6.1E-86 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS08090 93adce25961631370573718acfa9b348 332 Hamap MF_01694 Biotin synthase [bioB]. 15 322 41.084 T 06-07-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 GTHT12_RS08090 93adce25961631370573718acfa9b348 332 SMART SM00876 231 321 2.8E-34 T 06-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 GTHT12_RS08090 93adce25961631370573718acfa9b348 332 SUPERFAMILY SSF102114 15 321 3.66E-72 T 06-07-2017 GTHT12_RS08090 93adce25961631370573718acfa9b348 332 TIGRFAM TIGR00433 bioB: biotin synthase 28 320 2.7E-119 T 06-07-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 GTHT12_RS08090 93adce25961631370573718acfa9b348 332 SMART SM00729 55 263 3.1E-37 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 GTHT12_RS08090 93adce25961631370573718acfa9b348 332 PIRSF PIRSF001619 1 327 5.4E-121 T 06-07-2017 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 GTHT12_RS08090 93adce25961631370573718acfa9b348 332 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 231 320 1.1E-14 T 06-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 GTHT12_RS08090 93adce25961631370573718acfa9b348 332 Pfam PF04055 Radical SAM superfamily 65 220 1.4E-17 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 GTHT12_RS13910 8dc29052dbdce8317f9fe5e59ffca0df 204 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 193 6.1E-64 T 06-07-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 GTHT12_RS13910 8dc29052dbdce8317f9fe5e59ffca0df 204 Gene3D G3DSA:3.90.950.10 2 196 5.0E-83 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like GTHT12_RS13910 8dc29052dbdce8317f9fe5e59ffca0df 204 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 195 50.578 T 06-07-2017 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 GTHT12_RS13910 8dc29052dbdce8317f9fe5e59ffca0df 204 SUPERFAMILY SSF52972 2 193 1.39E-72 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like GTHT12_RS13910 8dc29052dbdce8317f9fe5e59ffca0df 204 Pfam PF01725 Ham1 family 4 191 8.1E-60 T 06-07-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 GTHT12_RS18100 7c6b14d97e1e6a7890416ecfab3e768e 405 Pfam PF13180 PDZ domain 302 400 9.7E-19 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS18100 7c6b14d97e1e6a7890416ecfab3e768e 405 PRINTS PR00834 HtrA/DegQ protease family signature 235 252 3.4E-35 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GTHT12_RS18100 7c6b14d97e1e6a7890416ecfab3e768e 405 PRINTS PR00834 HtrA/DegQ protease family signature 150 170 3.4E-35 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GTHT12_RS18100 7c6b14d97e1e6a7890416ecfab3e768e 405 PRINTS PR00834 HtrA/DegQ protease family signature 129 141 3.4E-35 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GTHT12_RS18100 7c6b14d97e1e6a7890416ecfab3e768e 405 PRINTS PR00834 HtrA/DegQ protease family signature 191 215 3.4E-35 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GTHT12_RS18100 7c6b14d97e1e6a7890416ecfab3e768e 405 PRINTS PR00834 HtrA/DegQ protease family signature 348 360 3.4E-35 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GTHT12_RS18100 7c6b14d97e1e6a7890416ecfab3e768e 405 PRINTS PR00834 HtrA/DegQ protease family signature 257 274 3.4E-35 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GTHT12_RS18100 7c6b14d97e1e6a7890416ecfab3e768e 405 SMART SM00228 302 391 6.4E-10 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS18100 7c6b14d97e1e6a7890416ecfab3e768e 405 Gene3D G3DSA:2.40.10.10 192 303 2.8E-43 T 06-07-2017 GTHT12_RS18100 7c6b14d97e1e6a7890416ecfab3e768e 405 Gene3D G3DSA:2.40.10.10 112 191 4.0E-26 T 06-07-2017 GTHT12_RS18100 7c6b14d97e1e6a7890416ecfab3e768e 405 SUPERFAMILY SSF50494 83 298 9.49E-56 T 06-07-2017 IPR009003 Peptidase S1, PA clan GTHT12_RS18100 7c6b14d97e1e6a7890416ecfab3e768e 405 Pfam PF13365 Trypsin-like peptidase domain 117 264 2.4E-30 T 06-07-2017 GTHT12_RS18100 7c6b14d97e1e6a7890416ecfab3e768e 405 SUPERFAMILY SSF50156 301 400 1.3E-19 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS18100 7c6b14d97e1e6a7890416ecfab3e768e 405 Gene3D G3DSA:2.30.42.10 304 402 4.7E-23 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS14040 238ed5b4636b7fcb2e77edd04a678232 575 SUPERFAMILY SSF89550 336 570 1.03E-57 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 GTHT12_RS14040 238ed5b4636b7fcb2e77edd04a678232 575 SMART SM00483 2 316 4.5E-72 T 06-07-2017 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 GTHT12_RS14040 238ed5b4636b7fcb2e77edd04a678232 575 Pfam PF02811 PHP domain 339 500 2.0E-8 T 06-07-2017 IPR004013 PHP domain GO:0003824 GTHT12_RS14040 238ed5b4636b7fcb2e77edd04a678232 575 Pfam PF14520 Helix-hairpin-helix domain 91 146 9.6E-5 T 06-07-2017 GTHT12_RS14040 238ed5b4636b7fcb2e77edd04a678232 575 Gene3D G3DSA:3.30.460.10 140 255 2.2E-12 T 06-07-2017 GTHT12_RS14040 238ed5b4636b7fcb2e77edd04a678232 575 Pfam PF14716 Helix-hairpin-helix domain 6 71 1.6E-20 T 06-07-2017 IPR010996 DNA polymerase beta-like, N-terminal domain GTHT12_RS14040 238ed5b4636b7fcb2e77edd04a678232 575 PIRSF PIRSF005047 3 572 6.0E-238 T 06-07-2017 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS14040 238ed5b4636b7fcb2e77edd04a678232 575 SMART SM00481 338 417 6.1E-21 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 GTHT12_RS14040 238ed5b4636b7fcb2e77edd04a678232 575 Gene3D G3DSA:3.30.210.10 256 316 2.4E-25 T 06-07-2017 IPR029398 DNA polymerase beta, thumb domain GTHT12_RS14040 238ed5b4636b7fcb2e77edd04a678232 575 Pfam PF14791 DNA polymerase beta thumb 254 316 5.3E-20 T 06-07-2017 IPR029398 DNA polymerase beta, thumb domain GTHT12_RS14040 238ed5b4636b7fcb2e77edd04a678232 575 SMART SM00278 50 69 24.0 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 GTHT12_RS14040 238ed5b4636b7fcb2e77edd04a678232 575 SMART SM00278 90 109 88.0 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 GTHT12_RS14040 238ed5b4636b7fcb2e77edd04a678232 575 SMART SM00278 125 144 28.0 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 GTHT12_RS14040 238ed5b4636b7fcb2e77edd04a678232 575 Gene3D G3DSA:1.10.8.310 6 84 8.1E-23 T 06-07-2017 IPR027420 DNA polymerase beta, N-terminal domain GTHT12_RS14040 238ed5b4636b7fcb2e77edd04a678232 575 SUPERFAMILY SSF81301 154 316 1.44E-43 T 06-07-2017 GTHT12_RS14040 238ed5b4636b7fcb2e77edd04a678232 575 SUPERFAMILY SSF47802 5 84 5.23E-21 T 06-07-2017 IPR010996 DNA polymerase beta-like, N-terminal domain GTHT12_RS14040 238ed5b4636b7fcb2e77edd04a678232 575 Gene3D G3DSA:3.20.20.140 336 571 1.1E-56 T 06-07-2017 GTHT12_RS09155 40479dbe7954219ab5fee31156d1bba7 471 Pfam PF02378 Phosphotransferase system, EIIC 112 408 1.4E-42 T 06-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 GTHT12_RS09155 40479dbe7954219ab5fee31156d1bba7 471 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 06-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 GTHT12_RS09155 40479dbe7954219ab5fee31156d1bba7 471 Pfam PF00367 phosphotransferase system, EIIB 10 42 1.0E-15 T 06-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 GTHT12_RS09155 40479dbe7954219ab5fee31156d1bba7 471 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 6 464 1.4E-205 T 06-07-2017 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 GTHT12_RS09155 40479dbe7954219ab5fee31156d1bba7 471 Gene3D G3DSA:3.30.1360.60 4 83 6.2E-28 T 06-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 GTHT12_RS09155 40479dbe7954219ab5fee31156d1bba7 471 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 4 463 4.6E-170 T 06-07-2017 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 GTHT12_RS09155 40479dbe7954219ab5fee31156d1bba7 471 SUPERFAMILY SSF55604 7 83 1.15E-21 T 06-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 GTHT12_RS09155 40479dbe7954219ab5fee31156d1bba7 471 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 29 111 2.2E-21 T 06-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 GTHT12_RS04220 983927e0ed76d2dd99dbf9a81af754b9 354 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 3 347 2.1E-132 T 06-07-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS04220 983927e0ed76d2dd99dbf9a81af754b9 354 Gene3D G3DSA:3.50.30.20 1 135 3.6E-50 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS04220 983927e0ed76d2dd99dbf9a81af754b9 354 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 2 130 2.9E-46 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS04220 983927e0ed76d2dd99dbf9a81af754b9 354 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 235 251 8.7E-32 T 06-07-2017 GTHT12_RS04220 983927e0ed76d2dd99dbf9a81af754b9 354 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 205 219 8.7E-32 T 06-07-2017 GTHT12_RS04220 983927e0ed76d2dd99dbf9a81af754b9 354 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 252 269 8.7E-32 T 06-07-2017 GTHT12_RS04220 983927e0ed76d2dd99dbf9a81af754b9 354 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 277 288 8.7E-32 T 06-07-2017 GTHT12_RS04220 983927e0ed76d2dd99dbf9a81af754b9 354 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 166 180 8.7E-32 T 06-07-2017 GTHT12_RS04220 983927e0ed76d2dd99dbf9a81af754b9 354 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 350 43.983 T 06-07-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS04220 983927e0ed76d2dd99dbf9a81af754b9 354 PRINTS PR00097 Anthranilate synthase component II signature 208 217 3.3E-6 T 06-07-2017 GTHT12_RS04220 983927e0ed76d2dd99dbf9a81af754b9 354 PRINTS PR00097 Anthranilate synthase component II signature 321 334 3.3E-6 T 06-07-2017 GTHT12_RS04220 983927e0ed76d2dd99dbf9a81af754b9 354 PRINTS PR00097 Anthranilate synthase component II signature 235 246 3.3E-6 T 06-07-2017 GTHT12_RS04220 983927e0ed76d2dd99dbf9a81af754b9 354 SUPERFAMILY SSF52317 148 347 5.4E-56 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS04220 983927e0ed76d2dd99dbf9a81af754b9 354 PRINTS PR00096 Glutamine amidotransferase superfamily signature 235 246 6.7E-11 T 06-07-2017 GTHT12_RS04220 983927e0ed76d2dd99dbf9a81af754b9 354 PRINTS PR00096 Glutamine amidotransferase superfamily signature 321 334 6.7E-11 T 06-07-2017 GTHT12_RS04220 983927e0ed76d2dd99dbf9a81af754b9 354 PRINTS PR00096 Glutamine amidotransferase superfamily signature 208 217 6.7E-11 T 06-07-2017 GTHT12_RS04220 983927e0ed76d2dd99dbf9a81af754b9 354 SMART SM01097 1 132 3.3E-68 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS04220 983927e0ed76d2dd99dbf9a81af754b9 354 Pfam PF00117 Glutamine amidotransferase class-I 167 344 3.0E-46 T 06-07-2017 IPR017926 Glutamine amidotransferase GTHT12_RS04220 983927e0ed76d2dd99dbf9a81af754b9 354 SUPERFAMILY SSF52021 1 136 1.83E-46 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS04220 983927e0ed76d2dd99dbf9a81af754b9 354 Gene3D G3DSA:3.40.50.880 153 348 5.2E-62 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS14650 bbc628b2404073d1621205f8393081be 358 Gene3D G3DSA:2.40.30.40 75 161 8.3E-36 T 06-07-2017 IPR023367 Peptidase M42, domain 2 GTHT12_RS14650 bbc628b2404073d1621205f8393081be 358 SUPERFAMILY SSF53187 4 81 3.39E-71 T 06-07-2017 GTHT12_RS14650 bbc628b2404073d1621205f8393081be 358 SUPERFAMILY SSF53187 172 352 3.39E-71 T 06-07-2017 GTHT12_RS14650 bbc628b2404073d1621205f8393081be 358 Pfam PF05343 M42 glutamyl aminopeptidase 46 338 1.9E-109 T 06-07-2017 IPR008007 Peptidase M42 GTHT12_RS14650 bbc628b2404073d1621205f8393081be 358 Gene3D G3DSA:3.40.630.10 4 74 3.5E-85 T 06-07-2017 GTHT12_RS14650 bbc628b2404073d1621205f8393081be 358 Gene3D G3DSA:3.40.630.10 171 354 3.5E-85 T 06-07-2017 GTHT12_RS14650 bbc628b2404073d1621205f8393081be 358 PIRSF PIRSF001123 2 357 3.2E-149 T 06-07-2017 IPR008007 Peptidase M42 GTHT12_RS14650 bbc628b2404073d1621205f8393081be 358 SUPERFAMILY SSF101821 71 180 1.1E-31 T 06-07-2017 GTHT12_RS07875 168709d98246435753c5e30a7f7097b9 452 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 87 98 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GTHT12_RS07875 168709d98246435753c5e30a7f7097b9 452 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 36 47 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GTHT12_RS07875 168709d98246435753c5e30a7f7097b9 452 Pfam PF13183 4Fe-4S dicluster domain 35 101 1.1E-11 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain GTHT12_RS07875 168709d98246435753c5e30a7f7097b9 452 Gene3D G3DSA:1.10.1060.10 33 115 3.1E-20 T 06-07-2017 GTHT12_RS07875 168709d98246435753c5e30a7f7097b9 452 PIRSF PIRSF000139 17 448 4.0E-152 T 06-07-2017 IPR012257 Glycolate oxidase, iron-sulphur subunit GTHT12_RS07875 168709d98246435753c5e30a7f7097b9 452 SUPERFAMILY SSF46548 33 115 1.26E-17 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 GTHT12_RS07875 168709d98246435753c5e30a7f7097b9 452 Pfam PF02754 Cysteine-rich domain 208 289 4.2E-14 T 06-07-2017 IPR004017 Cysteine-rich domain GTHT12_RS07875 168709d98246435753c5e30a7f7097b9 452 Pfam PF02754 Cysteine-rich domain 336 418 1.8E-12 T 06-07-2017 IPR004017 Cysteine-rich domain GTHT12_RS06775 164ac078ea5de2364ce4c5a5ffbd98ed 347 Gene3D G3DSA:3.90.1720.10 219 346 1.4E-43 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain GTHT12_RS06775 164ac078ea5de2364ce4c5a5ffbd98ed 347 SMART SM00257 80 125 1.0E-14 T 06-07-2017 IPR018392 LysM domain GTHT12_RS06775 164ac078ea5de2364ce4c5a5ffbd98ed 347 SMART SM00257 25 68 1.2E-17 T 06-07-2017 IPR018392 LysM domain GTHT12_RS06775 164ac078ea5de2364ce4c5a5ffbd98ed 347 SMART SM00257 146 191 7.5E-14 T 06-07-2017 IPR018392 LysM domain GTHT12_RS06775 164ac078ea5de2364ce4c5a5ffbd98ed 347 SUPERFAMILY SSF54001 221 346 9.07E-40 T 06-07-2017 GTHT12_RS06775 164ac078ea5de2364ce4c5a5ffbd98ed 347 SUPERFAMILY SSF54106 79 124 1.83E-10 T 06-07-2017 IPR018392 LysM domain GTHT12_RS06775 164ac078ea5de2364ce4c5a5ffbd98ed 347 Pfam PF01476 LysM domain 147 190 1.6E-12 T 06-07-2017 IPR018392 LysM domain GTHT12_RS06775 164ac078ea5de2364ce4c5a5ffbd98ed 347 Pfam PF01476 LysM domain 81 124 5.5E-13 T 06-07-2017 IPR018392 LysM domain GTHT12_RS06775 164ac078ea5de2364ce4c5a5ffbd98ed 347 Pfam PF01476 LysM domain 26 67 1.4E-15 T 06-07-2017 IPR018392 LysM domain GTHT12_RS06775 164ac078ea5de2364ce4c5a5ffbd98ed 347 SUPERFAMILY SSF54106 25 67 6.54E-13 T 06-07-2017 IPR018392 LysM domain GTHT12_RS06775 164ac078ea5de2364ce4c5a5ffbd98ed 347 Pfam PF00877 NlpC/P60 family 237 344 4.0E-29 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain GTHT12_RS06775 164ac078ea5de2364ce4c5a5ffbd98ed 347 Gene3D G3DSA:3.10.350.10 146 191 6.9E-14 T 06-07-2017 IPR018392 LysM domain GTHT12_RS06775 164ac078ea5de2364ce4c5a5ffbd98ed 347 Gene3D G3DSA:3.10.350.10 24 67 2.7E-19 T 06-07-2017 IPR018392 LysM domain GTHT12_RS06775 164ac078ea5de2364ce4c5a5ffbd98ed 347 Gene3D G3DSA:3.10.350.10 79 125 3.5E-16 T 06-07-2017 IPR018392 LysM domain GTHT12_RS06775 164ac078ea5de2364ce4c5a5ffbd98ed 347 SUPERFAMILY SSF54106 147 190 1.7E-9 T 06-07-2017 IPR018392 LysM domain GTHT12_RS15030 aa7863cc07ee6d1a3f6959f903c3fd50 176 Gene3D G3DSA:1.20.120.450 10 149 7.2E-42 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase GTHT12_RS15030 aa7863cc07ee6d1a3f6959f903c3fd50 176 SUPERFAMILY SSF109854 16 161 6.11E-31 T 06-07-2017 GTHT12_RS15030 aa7863cc07ee6d1a3f6959f903c3fd50 176 Pfam PF05163 DinB family 10 166 4.7E-32 T 06-07-2017 IPR007837 DNA damage-inducible protein DinB GTHT12_RS07585 742f97b49e7860c50983a7ebec77904d 150 Gene3D G3DSA:3.40.630.30 11 138 5.0E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS07585 742f97b49e7860c50983a7ebec77904d 150 Pfam PF13673 Acetyltransferase (GNAT) domain 47 149 3.5E-19 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS07585 742f97b49e7860c50983a7ebec77904d 150 SUPERFAMILY SSF55729 14 144 7.55E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS11515 e55fbfdb23b3e99d54be863feabd7e20 911 Pfam PF13307 Helicase C-terminal domain 727 891 2.1E-36 T 06-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 GTHT12_RS11515 e55fbfdb23b3e99d54be863feabd7e20 911 SUPERFAMILY SSF52540 700 872 6.74E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11515 e55fbfdb23b3e99d54be863feabd7e20 911 SUPERFAMILY SSF52540 272 326 6.74E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11515 e55fbfdb23b3e99d54be863feabd7e20 911 SUPERFAMILY SSF52540 653 667 6.74E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11515 e55fbfdb23b3e99d54be863feabd7e20 911 SUPERFAMILY SSF52540 408 482 6.74E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11515 e55fbfdb23b3e99d54be863feabd7e20 911 SUPERFAMILY SSF53098 2 182 6.28E-53 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS11515 e55fbfdb23b3e99d54be863feabd7e20 911 Gene3D G3DSA:3.30.420.10 2 175 1.3E-52 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS11515 e55fbfdb23b3e99d54be863feabd7e20 911 Gene3D G3DSA:3.40.50.300 655 664 2.3E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11515 e55fbfdb23b3e99d54be863feabd7e20 911 Gene3D G3DSA:3.40.50.300 271 351 2.3E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11515 e55fbfdb23b3e99d54be863feabd7e20 911 Gene3D G3DSA:3.40.50.300 420 485 2.3E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11515 e55fbfdb23b3e99d54be863feabd7e20 911 Pfam PF00929 Exonuclease 6 162 4.4E-27 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III GTHT12_RS11515 e55fbfdb23b3e99d54be863feabd7e20 911 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 5 173 1.9E-21 T 06-07-2017 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS11515 e55fbfdb23b3e99d54be863feabd7e20 911 Pfam PF04851 Type III restriction enzyme, res subunit 257 463 2.7E-5 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 GTHT12_RS11515 e55fbfdb23b3e99d54be863feabd7e20 911 TIGRFAM TIGR01407 dinG_rel: putative DnaQ family exonuclease/DinG family helicase 4 909 7.2E-239 T 06-07-2017 IPR006310 DnaQ exonuclease/DinG helicase, predicted GTHT12_RS11515 e55fbfdb23b3e99d54be863feabd7e20 911 SMART SM00491 744 878 2.4E-34 T 06-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 GTHT12_RS11515 e55fbfdb23b3e99d54be863feabd7e20 911 Gene3D G3DSA:3.40.50.300 721 866 1.0E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11515 e55fbfdb23b3e99d54be863feabd7e20 911 SMART SM00487 254 517 3.6E-6 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain GTHT12_RS11515 e55fbfdb23b3e99d54be863feabd7e20 911 SMART SM00479 4 171 3.4E-39 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III GTHT12_RS01020 f680e0a7536006a4ffac7570918257ff 261 Pfam PF00106 short chain dehydrogenase 9 200 1.0E-60 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01020 f680e0a7536006a4ffac7570918257ff 261 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 11 260 3.8E-120 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 GTHT12_RS01020 f680e0a7536006a4ffac7570918257ff 261 Gene3D G3DSA:3.40.50.720 2 259 5.4E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS01020 f680e0a7536006a4ffac7570918257ff 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GTHT12_RS01020 f680e0a7536006a4ffac7570918257ff 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 8.1E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01020 f680e0a7536006a4ffac7570918257ff 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 8.1E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01020 f680e0a7536006a4ffac7570918257ff 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 8.1E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01020 f680e0a7536006a4ffac7570918257ff 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 179 0.0016 T 06-07-2017 GTHT12_RS01020 f680e0a7536006a4ffac7570918257ff 261 SUPERFAMILY SSF51735 8 259 3.21E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS01020 f680e0a7536006a4ffac7570918257ff 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 237 256 3.5E-59 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 GTHT12_RS01020 f680e0a7536006a4ffac7570918257ff 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 172 195 3.5E-59 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 GTHT12_RS01020 f680e0a7536006a4ffac7570918257ff 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 211 230 3.5E-59 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 GTHT12_RS01020 f680e0a7536006a4ffac7570918257ff 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 15 32 3.5E-59 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 GTHT12_RS01020 f680e0a7536006a4ffac7570918257ff 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 107 127 3.5E-59 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 GTHT12_RS01020 f680e0a7536006a4ffac7570918257ff 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 87 104 3.5E-59 T 06-07-2017 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 Pfam PF00989 PAS fold 395 481 1.1E-12 T 06-07-2017 IPR013767 PAS fold GO:0006355 GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 Pfam PF00989 PAS fold 274 342 8.1E-9 T 06-07-2017 IPR013767 PAS fold GO:0006355 GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 Gene3D G3DSA:3.30.565.10 582 728 4.9E-47 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 SUPERFAMILY SSF55874 574 730 1.96E-44 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 SUPERFAMILY SSF47384 511 579 3.34E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 PRINTS PR00344 Bacterial sensor protein C-terminal signature 660 674 1.1E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 PRINTS PR00344 Bacterial sensor protein C-terminal signature 678 688 1.1E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 PRINTS PR00344 Bacterial sensor protein C-terminal signature 689 707 1.1E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 PRINTS PR00344 Bacterial sensor protein C-terminal signature 713 726 1.1E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 SUPERFAMILY SSF55785 379 471 5.58E-21 T 06-07-2017 IPR000014 PAS domain GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 SMART SM00091 32 100 8.6E-7 T 06-07-2017 IPR000014 PAS domain GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 SMART SM00091 153 219 0.002 T 06-07-2017 IPR000014 PAS domain GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 SMART SM00091 274 342 1.1E-8 T 06-07-2017 IPR000014 PAS domain GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 SMART SM00091 394 460 1.3E-10 T 06-07-2017 IPR000014 PAS domain GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 Pfam PF00512 His Kinase A (phospho-acceptor) domain 519 579 1.0E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 SUPERFAMILY SSF55785 138 260 1.08E-15 T 06-07-2017 IPR000014 PAS domain GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 Gene3D G3DSA:3.30.450.20 380 482 3.5E-22 T 06-07-2017 GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 Pfam PF08448 PAS fold 159 263 4.2E-8 T 06-07-2017 IPR013656 PAS fold-4 GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 SUPERFAMILY SSF55785 259 363 9.6E-18 T 06-07-2017 IPR000014 PAS domain GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 154 268 7.4E-13 T 06-07-2017 IPR000014 PAS domain GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 28 80 2.5E-8 T 06-07-2017 IPR000014 PAS domain GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 390 509 1.7E-16 T 06-07-2017 IPR000014 PAS domain GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 270 389 4.7E-9 T 06-07-2017 IPR000014 PAS domain GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 SMART SM00387 623 729 2.6E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 Gene3D G3DSA:3.30.450.20 260 363 6.9E-18 T 06-07-2017 GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 SUPERFAMILY SSF55785 24 123 1.5E-12 T 06-07-2017 IPR000014 PAS domain GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 Gene3D G3DSA:1.10.287.130 518 577 4.6E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 Gene3D G3DSA:3.30.450.20 24 123 1.1E-12 T 06-07-2017 GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 Gene3D G3DSA:3.30.450.20 151 259 3.0E-16 T 06-07-2017 GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 Pfam PF13426 PAS domain 43 139 1.2E-6 T 06-07-2017 IPR000014 PAS domain GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 SMART SM00388 517 581 1.2E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS05000 878e2ca92840c8d099d5292b98c3bca8 738 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 625 728 7.6E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS05635 cffdb50067b5c37807a6a9f36777d0fb 614 Pfam PF14492 Elongation Factor G, domain II 331 380 2.1E-7 T 06-07-2017 IPR009022 Elongation factor G, III-V domain GTHT12_RS05635 cffdb50067b5c37807a6a9f36777d0fb 614 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 8 602 7.2E-291 T 06-07-2017 IPR006298 GTP-binding protein TypA GO:0005525 GTHT12_RS05635 cffdb50067b5c37807a6a9f36777d0fb 614 Gene3D G3DSA:3.30.70.240 404 482 2.8E-34 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain GTHT12_RS05635 cffdb50067b5c37807a6a9f36777d0fb 614 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 146 1.3E-22 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 GTHT12_RS05635 cffdb50067b5c37807a6a9f36777d0fb 614 Gene3D G3DSA:2.40.30.10 208 306 1.3E-28 T 06-07-2017 GTHT12_RS05635 cffdb50067b5c37807a6a9f36777d0fb 614 PRINTS PR00315 GTP-binding elongation factor signature 54 62 7.2E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GTHT12_RS05635 cffdb50067b5c37807a6a9f36777d0fb 614 PRINTS PR00315 GTP-binding elongation factor signature 74 84 7.2E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GTHT12_RS05635 cffdb50067b5c37807a6a9f36777d0fb 614 PRINTS PR00315 GTP-binding elongation factor signature 10 23 7.2E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GTHT12_RS05635 cffdb50067b5c37807a6a9f36777d0fb 614 PRINTS PR00315 GTP-binding elongation factor signature 126 135 7.2E-13 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GTHT12_RS05635 cffdb50067b5c37807a6a9f36777d0fb 614 Gene3D G3DSA:2.40.50.250 486 580 1.0E-41 T 06-07-2017 GTHT12_RS05635 cffdb50067b5c37807a6a9f36777d0fb 614 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site GTHT12_RS05635 cffdb50067b5c37807a6a9f36777d0fb 614 Gene3D G3DSA:3.30.70.870 307 403 4.1E-39 T 06-07-2017 GTHT12_RS05635 cffdb50067b5c37807a6a9f36777d0fb 614 SMART SM00838 398 486 9.1E-6 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain GTHT12_RS05635 cffdb50067b5c37807a6a9f36777d0fb 614 Pfam PF00679 Elongation factor G C-terminus 399 480 1.7E-25 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain GTHT12_RS05635 cffdb50067b5c37807a6a9f36777d0fb 614 Pfam PF00009 Elongation factor Tu GTP binding domain 8 198 1.9E-55 T 06-07-2017 GTHT12_RS05635 cffdb50067b5c37807a6a9f36777d0fb 614 SUPERFAMILY SSF50447 155 303 1.26E-33 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain GTHT12_RS05635 cffdb50067b5c37807a6a9f36777d0fb 614 Pfam PF03144 Elongation factor Tu domain 2 222 292 6.2E-13 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 GTHT12_RS05635 cffdb50067b5c37807a6a9f36777d0fb 614 Gene3D G3DSA:3.40.50.300 4 207 8.1E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05635 cffdb50067b5c37807a6a9f36777d0fb 614 SUPERFAMILY SSF54980 401 516 1.82E-31 T 06-07-2017 IPR009022 Elongation factor G, III-V domain GTHT12_RS05635 cffdb50067b5c37807a6a9f36777d0fb 614 SUPERFAMILY SSF54980 305 390 3.31E-16 T 06-07-2017 IPR009022 Elongation factor G, III-V domain GTHT12_RS05635 cffdb50067b5c37807a6a9f36777d0fb 614 SUPERFAMILY SSF52540 7 210 4.1E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 Gene3D G3DSA:3.30.70.100 14 65 6.2E-12 T 06-07-2017 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 173 685 2.7E-96 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 SUPERFAMILY SSF56784 399 419 3.87E-56 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 SUPERFAMILY SSF56784 459 705 3.87E-56 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 ProSitePatterns PS01047 Heavy-metal-associated domain. 18 47 - T 06-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 Pfam PF00122 E1-E2 ATPase 172 391 7.4E-67 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 403 409 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 150 707 3.2E-190 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 PRINTS PR00941 Cadmium-transporting ATPase signature 185 205 1.3E-76 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 PRINTS PR00941 Cadmium-transporting ATPase signature 49 72 1.3E-76 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 PRINTS PR00941 Cadmium-transporting ATPase signature 266 282 1.3E-76 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 PRINTS PR00941 Cadmium-transporting ATPase signature 285 299 1.3E-76 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 PRINTS PR00941 Cadmium-transporting ATPase signature 131 143 1.3E-76 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 PRINTS PR00941 Cadmium-transporting ATPase signature 27 48 1.3E-76 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 PRINTS PR00941 Cadmium-transporting ATPase signature 114 131 1.3E-76 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 PRINTS PR00941 Cadmium-transporting ATPase signature 16 25 1.3E-76 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 PRINTS PR00941 Cadmium-transporting ATPase signature 205 221 1.3E-76 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 SUPERFAMILY SSF81653 203 300 2.35E-26 T 06-07-2017 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 151 461 1.3E-98 T 06-07-2017 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 Pfam PF00403 Heavy-metal-associated domain 15 65 8.5E-11 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 SUPERFAMILY SSF81665 301 395 1.1E-20 T 06-07-2017 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 SUPERFAMILY SSF81665 150 204 1.1E-20 T 06-07-2017 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 SUPERFAMILY SSF81665 654 694 1.1E-20 T 06-07-2017 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 Gene3D G3DSA:3.40.1110.10 423 529 1.8E-20 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 132 707 4.8E-125 T 06-07-2017 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 Gene3D G3DSA:3.40.50.1000 530 674 9.2E-44 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 Gene3D G3DSA:2.70.150.10 195 301 5.6E-30 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 551 561 7.8E-23 T 06-07-2017 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 604 623 7.8E-23 T 06-07-2017 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 250 264 7.8E-23 T 06-07-2017 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 401 415 7.8E-23 T 06-07-2017 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 528 539 7.8E-23 T 06-07-2017 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 628 640 7.8E-23 T 06-07-2017 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 Gene3D G3DSA:3.40.1110.10 392 422 9.9E-5 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 SUPERFAMILY SSF55008 12 66 6.94E-12 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 GTHT12_RS14515 60ed3679cabc747ba156e47750b7961d 712 Pfam PF00702 haloacid dehalogenase-like hydrolase 398 616 2.6E-46 T 06-07-2017 GTHT12_RS06635 009b69d7d86d8e9150c89ac6066f8a28 74 Pfam PF14035 YlzJ-like protein 3 66 8.1E-24 T 06-07-2017 IPR025619 YlzJ-like protein GTHT12_RS05470 acdfab51da93df293faf497389e144fc 393 SUPERFAMILY SSF55073 237 390 1.8E-42 T 06-07-2017 IPR029787 Nucleotide cyclase GTHT12_RS05470 acdfab51da93df293faf497389e144fc 393 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 230 391 5.5E-44 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS05470 acdfab51da93df293faf497389e144fc 393 Gene3D G3DSA:3.30.70.270 234 391 3.9E-46 T 06-07-2017 GTHT12_RS05470 acdfab51da93df293faf497389e144fc 393 Gene3D G3DSA:3.40.50.2300 102 230 1.8E-12 T 06-07-2017 GTHT12_RS05470 acdfab51da93df293faf497389e144fc 393 Pfam PF00072 Response regulator receiver domain 107 218 5.8E-5 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS05470 acdfab51da93df293faf497389e144fc 393 SMART SM00267 221 393 4.2E-41 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS05470 acdfab51da93df293faf497389e144fc 393 Pfam PF00990 Diguanylate cyclase, GGDEF domain 233 388 2.0E-36 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS05470 acdfab51da93df293faf497389e144fc 393 SUPERFAMILY SSF52172 104 234 1.71E-14 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS08005 9e509d560ffb92094756b9788930a9ab 355 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 217 352 4.2E-20 T 06-07-2017 IPR012328 Chalcone/stilbene synthase, C-terminal GTHT12_RS08005 9e509d560ffb92094756b9788930a9ab 355 SUPERFAMILY SSF53901 55 353 2.98E-47 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS08005 9e509d560ffb92094756b9788930a9ab 355 Gene3D G3DSA:3.40.47.10 2 206 5.2E-49 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS08005 9e509d560ffb92094756b9788930a9ab 355 ProSitePatterns PS00441 Chalcone and stilbene synthases active site. 134 150 - T 06-07-2017 IPR018088 Chalcone/stilbene synthase, active site GO:0009058|GO:0016746 KEGG: 00941+2.3.1.74|MetaCyc: PWY-5135|MetaCyc: PWY-6316|MetaCyc: PWY-6787|MetaCyc: PWY-7397 GTHT12_RS08005 9e509d560ffb92094756b9788930a9ab 355 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 71 204 2.8E-15 T 06-07-2017 IPR001099 Chalcone/stilbene synthase, N-terminal GTHT12_RS08005 9e509d560ffb92094756b9788930a9ab 355 Gene3D G3DSA:3.40.47.10 214 353 1.2E-37 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS08005 9e509d560ffb92094756b9788930a9ab 355 PIRSF PIRSF000451 1 355 9.9E-113 T 06-07-2017 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 GTHT12_RS07755 34dcfccbd9a592e10bde62d3a52d18a5 340 Pfam PF00535 Glycosyl transferase family 2 8 176 1.1E-26 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 GTHT12_RS07755 34dcfccbd9a592e10bde62d3a52d18a5 340 Gene3D G3DSA:3.90.550.10 2 143 1.6E-18 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS07755 34dcfccbd9a592e10bde62d3a52d18a5 340 SUPERFAMILY SSF53448 2 228 2.72E-28 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS08870 b887815f76879acae4096c98d7cb09d5 524 SUPERFAMILY SSF52540 4 166 1.37E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08870 b887815f76879acae4096c98d7cb09d5 524 Gene3D G3DSA:3.40.50.300 73 198 1.4E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08870 b887815f76879acae4096c98d7cb09d5 524 ProSitePatterns PS00211 ABC transporters family signature. 385 399 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS08870 b887815f76879acae4096c98d7cb09d5 524 Gene3D G3DSA:3.40.50.300 273 482 2.0E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08870 b887815f76879acae4096c98d7cb09d5 524 Gene3D G3DSA:3.40.50.300 4 72 2.0E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08870 b887815f76879acae4096c98d7cb09d5 524 Pfam PF00005 ABC transporter 23 61 1.9E-9 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS08870 b887815f76879acae4096c98d7cb09d5 524 Pfam PF00005 ABC transporter 289 413 4.8E-19 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS08870 b887815f76879acae4096c98d7cb09d5 524 Pfam PF12848 ABC transporter 146 208 2.0E-8 T 06-07-2017 IPR032781 ABC-transporter extension domain GTHT12_RS08870 b887815f76879acae4096c98d7cb09d5 524 SUPERFAMILY SSF52540 265 478 3.29E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08870 b887815f76879acae4096c98d7cb09d5 524 SMART SM00382 297 458 2.8E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS08870 b887815f76879acae4096c98d7cb09d5 524 SMART SM00382 28 151 6.4E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS02175 adc0f1b632d3d51385e1eba39d94dd47 253 Pfam PF07070 SpoOM protein 2 211 2.6E-82 T 06-07-2017 IPR009776 Sporulation stage 0, protein M GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 SMART SM00878 346 453 5.1E-52 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 SUPERFAMILY SSF51230 1070 1145 1.1E-22 T 06-07-2017 IPR011053 Single hybrid motif GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 SUPERFAMILY SSF89000 834 1011 4.32E-62 T 06-07-2017 GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 Pfam PF02436 Conserved carboxylase domain 829 1029 2.1E-81 T 06-07-2017 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 SUPERFAMILY SSF52440 3 117 3.74E-45 T 06-07-2017 IPR016185 Pre-ATP-grasp domain GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 Gene3D G3DSA:3.30.470.20 208 459 6.2E-98 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 SUPERFAMILY SSF51246 341 460 3.19E-38 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 Gene3D G3DSA:3.30.1490.20 135 206 2.1E-29 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 SUPERFAMILY SSF51569 526 837 3.85E-84 T 06-07-2017 GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 120 326 1.0E-79 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 PIRSF PIRSF001594 1 1147 0.0 T 06-07-2017 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 8 1145 0.0 T 06-07-2017 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 Pfam PF02785 Biotin carboxylase C-terminal domain 346 453 7.6E-32 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 Gene3D G3DSA:1.10.10.60 952 988 3.8E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 Gene3D G3DSA:3.10.600.10 989 1066 1.8E-38 T 06-07-2017 GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 Gene3D G3DSA:3.40.50.20 6 134 1.1E-49 T 06-07-2017 IPR016185 Pre-ATP-grasp domain GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 Pfam PF00682 HMGL-like 534 806 1.9E-26 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 Gene3D G3DSA:3.20.20.70 511 820 8.1E-137 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 158 172 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 Pfam PF00289 Biotin carboxylase, N-terminal domain 6 114 2.1E-42 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 Pfam PF00364 Biotin-requiring enzyme 1079 1145 1.9E-18 T 06-07-2017 IPR000089 Biotin/lipoyl attachment GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 SUPERFAMILY SSF56059 88 334 6.54E-70 T 06-07-2017 GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 290 297 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GTHT12_RS05680 09e65912920318a878dceefc000e7c11 1147 Gene3D G3DSA:2.40.50.100 1069 1145 2.2E-26 T 06-07-2017 GTHT12_RS10890 049c64bf7756d458179073a281621caf 377 Gene3D G3DSA:3.90.350.10 174 295 2.7E-5 T 06-07-2017 IPR014736 Transposase, Tn5-like, core GTHT12_RS10890 049c64bf7756d458179073a281621caf 377 SUPERFAMILY SSF53098 84 335 9.86E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS10890 049c64bf7756d458179073a281621caf 377 Pfam PF01609 Transposase DDE domain 110 320 1.6E-32 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 GTHT12_RS07475 049c64bf7756d458179073a281621caf 377 Gene3D G3DSA:3.90.350.10 174 295 2.7E-5 T 06-07-2017 IPR014736 Transposase, Tn5-like, core GTHT12_RS07475 049c64bf7756d458179073a281621caf 377 SUPERFAMILY SSF53098 84 335 9.86E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS07475 049c64bf7756d458179073a281621caf 377 Pfam PF01609 Transposase DDE domain 110 320 1.6E-32 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 GTHT12_RS01740 049c64bf7756d458179073a281621caf 377 Gene3D G3DSA:3.90.350.10 174 295 2.7E-5 T 06-07-2017 IPR014736 Transposase, Tn5-like, core GTHT12_RS01740 049c64bf7756d458179073a281621caf 377 SUPERFAMILY SSF53098 84 335 9.86E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS01740 049c64bf7756d458179073a281621caf 377 Pfam PF01609 Transposase DDE domain 110 320 1.6E-32 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 GTHT12_RS12175 049c64bf7756d458179073a281621caf 377 Gene3D G3DSA:3.90.350.10 174 295 2.7E-5 T 06-07-2017 IPR014736 Transposase, Tn5-like, core GTHT12_RS12175 049c64bf7756d458179073a281621caf 377 SUPERFAMILY SSF53098 84 335 9.86E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS12175 049c64bf7756d458179073a281621caf 377 Pfam PF01609 Transposase DDE domain 110 320 1.6E-32 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 GTHT12_RS05230 049c64bf7756d458179073a281621caf 377 Gene3D G3DSA:3.90.350.10 174 295 2.7E-5 T 06-07-2017 IPR014736 Transposase, Tn5-like, core GTHT12_RS05230 049c64bf7756d458179073a281621caf 377 SUPERFAMILY SSF53098 84 335 9.86E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS05230 049c64bf7756d458179073a281621caf 377 Pfam PF01609 Transposase DDE domain 110 320 1.6E-32 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 GTHT12_RS17955 049c64bf7756d458179073a281621caf 377 Gene3D G3DSA:3.90.350.10 174 295 2.7E-5 T 06-07-2017 IPR014736 Transposase, Tn5-like, core GTHT12_RS17955 049c64bf7756d458179073a281621caf 377 SUPERFAMILY SSF53098 84 335 9.86E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS17955 049c64bf7756d458179073a281621caf 377 Pfam PF01609 Transposase DDE domain 110 320 1.6E-32 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 GTHT12_RS04750 049c64bf7756d458179073a281621caf 377 Gene3D G3DSA:3.90.350.10 174 295 2.7E-5 T 06-07-2017 IPR014736 Transposase, Tn5-like, core GTHT12_RS04750 049c64bf7756d458179073a281621caf 377 SUPERFAMILY SSF53098 84 335 9.86E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS04750 049c64bf7756d458179073a281621caf 377 Pfam PF01609 Transposase DDE domain 110 320 1.6E-32 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 GTHT12_RS15785 db90ebdb77d044e2a754c245a74099f3 215 SUPERFAMILY SSF46785 6 74 1.65E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS15785 db90ebdb77d044e2a754c245a74099f3 215 SMART SM00895 80 206 1.4E-9 T 06-07-2017 IPR011711 GntR, C-terminal GTHT12_RS15785 db90ebdb77d044e2a754c245a74099f3 215 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 41 9.3E-5 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 GTHT12_RS15785 db90ebdb77d044e2a754c245a74099f3 215 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 41 60 9.3E-5 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 GTHT12_RS15785 db90ebdb77d044e2a754c245a74099f3 215 Pfam PF07729 FCD domain 82 203 1.2E-24 T 06-07-2017 IPR011711 GntR, C-terminal GTHT12_RS15785 db90ebdb77d044e2a754c245a74099f3 215 Gene3D G3DSA:1.10.10.10 4 71 2.1E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS15785 db90ebdb77d044e2a754c245a74099f3 215 SUPERFAMILY SSF48008 76 211 3.66E-21 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal GTHT12_RS15785 db90ebdb77d044e2a754c245a74099f3 215 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 70 5.0E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS15785 db90ebdb77d044e2a754c245a74099f3 215 Gene3D G3DSA:1.20.120.530 74 213 3.2E-28 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal GTHT12_RS15785 db90ebdb77d044e2a754c245a74099f3 215 SMART SM00345 12 70 5.0E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS17170 f1b12d45dd836f26cdd1a9b1d91ffd6f 680 SUPERFAMILY SSF52540 334 475 6.11E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17170 f1b12d45dd836f26cdd1a9b1d91ffd6f 680 SUPERFAMILY SSF52540 509 589 6.11E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17170 f1b12d45dd836f26cdd1a9b1d91ffd6f 680 Pfam PF07728 AAA domain (dynein-related subfamily) 347 537 2.3E-6 T 06-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 GTHT12_RS17170 f1b12d45dd836f26cdd1a9b1d91ffd6f 680 SMART SM00382 343 547 0.0059 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS17170 f1b12d45dd836f26cdd1a9b1d91ffd6f 680 Gene3D G3DSA:3.40.50.300 233 262 5.5E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17170 f1b12d45dd836f26cdd1a9b1d91ffd6f 680 Gene3D G3DSA:3.40.50.300 509 556 5.5E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17170 f1b12d45dd836f26cdd1a9b1d91ffd6f 680 Gene3D G3DSA:3.40.50.300 344 476 5.5E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17170 f1b12d45dd836f26cdd1a9b1d91ffd6f 680 Gene3D G3DSA:3.40.50.300 263 285 0.001 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS04000 7dbe946a127cccb17e48e59ffe64f055 163 SUPERFAMILY SSF89963 6 90 9.68E-30 T 06-07-2017 IPR007551 Protein of unknown function DUF520 GTHT12_RS04000 7dbe946a127cccb17e48e59ffe64f055 163 Pfam PF04461 Protein of unknown function (DUF520) 5 163 4.6E-62 T 06-07-2017 IPR007551 Protein of unknown function DUF520 GTHT12_RS04000 7dbe946a127cccb17e48e59ffe64f055 163 Gene3D G3DSA:3.30.70.860 98 163 2.0E-28 T 06-07-2017 GTHT12_RS04000 7dbe946a127cccb17e48e59ffe64f055 163 Gene3D G3DSA:3.30.70.990 12 97 3.3E-32 T 06-07-2017 GTHT12_RS04000 7dbe946a127cccb17e48e59ffe64f055 163 SUPERFAMILY SSF89963 92 163 2.09E-25 T 06-07-2017 IPR007551 Protein of unknown function DUF520 GTHT12_RS04000 7dbe946a127cccb17e48e59ffe64f055 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 4 163 26.411 T 06-07-2017 IPR007551 Protein of unknown function DUF520 GTHT12_RS01430 531ea92ab6698027b08d9e253cad925c 150 Pfam PF00583 Acetyltransferase (GNAT) family 53 126 8.5E-17 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS01430 531ea92ab6698027b08d9e253cad925c 150 Gene3D G3DSA:3.40.630.30 4 149 4.1E-37 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS01430 531ea92ab6698027b08d9e253cad925c 150 SUPERFAMILY SSF55729 4 149 7.43E-37 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS01430 531ea92ab6698027b08d9e253cad925c 150 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 14 145 3.8E-46 T 06-07-2017 IPR006464 Ribosomal-protein-alanine acetyltransferase GO:0006474|GO:0016407 GTHT12_RS06720 f3647485c0a69b9792181964726bdeea 518 Pfam PF00013 KH domain 212 266 6.3E-6 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 GTHT12_RS06720 f3647485c0a69b9792181964726bdeea 518 Pfam PF01966 HD domain 335 426 1.2E-18 T 06-07-2017 IPR006674 HD domain GTHT12_RS06720 f3647485c0a69b9792181964726bdeea 518 SUPERFAMILY SSF54791 206 302 3.04E-16 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 GTHT12_RS06720 f3647485c0a69b9792181964726bdeea 518 SMART SM00322 206 273 1.1E-6 T 06-07-2017 IPR004087 K Homology domain GO:0003676 GTHT12_RS06720 f3647485c0a69b9792181964726bdeea 518 TIGRFAM TIGR00277 HDIG: HDIG domain 330 407 5.1E-26 T 06-07-2017 IPR006675 HDIG domain GTHT12_RS06720 f3647485c0a69b9792181964726bdeea 518 Pfam PF12072 Domain of unknown function (DUF3552) 4 203 1.0E-76 T 06-07-2017 IPR022711 Ribonuclease Y, N-terminal GTHT12_RS06720 f3647485c0a69b9792181964726bdeea 518 Gene3D G3DSA:3.30.1370.10 218 295 2.1E-7 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 GTHT12_RS06720 f3647485c0a69b9792181964726bdeea 518 Hamap MF_00335 Ribonuclease Y [rny]. 3 518 26.15 T 06-07-2017 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 GTHT12_RS06720 f3647485c0a69b9792181964726bdeea 518 SUPERFAMILY SSF109604 314 465 2.24E-31 T 06-07-2017 GTHT12_RS06720 f3647485c0a69b9792181964726bdeea 518 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 6 518 1.3E-247 T 06-07-2017 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 GTHT12_RS06720 f3647485c0a69b9792181964726bdeea 518 SMART SM00471 330 436 4.4E-14 T 06-07-2017 IPR003607 HD/PDEase domain GTHT12_RS06720 f3647485c0a69b9792181964726bdeea 518 Gene3D G3DSA:1.10.3210.10 314 494 1.8E-44 T 06-07-2017 IPR006674 HD domain GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 SUPERFAMILY SSF55666 451 550 3.76E-30 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 4 694 31.484 T 06-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 SUPERFAMILY SSF55666 145 236 6.54E-32 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 Gene3D G3DSA:3.30.1370.10 552 617 9.3E-26 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 SUPERFAMILY SSF54211 292 489 1.11E-50 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 SMART SM00322 553 618 1.7E-12 T 06-07-2017 IPR004087 K Homology domain GO:0003676 GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 PIRSF PIRSF005499 2 721 0.0 T 06-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 Pfam PF00575 S1 RNA binding domain 620 691 1.5E-19 T 06-07-2017 IPR003029 S1 domain GO:0003676 GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 2.3E-15 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 Pfam PF03725 3' exoribonuclease family, domain 2 460 530 2.1E-8 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 SUPERFAMILY SSF54211 8 144 1.97E-49 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 12 693 0.0 T 06-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 Pfam PF01138 3' exoribonuclease family, domain 1 324 457 1.6E-19 T 06-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 Pfam PF01138 3' exoribonuclease family, domain 1 14 144 4.5E-22 T 06-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 Gene3D G3DSA:2.40.50.140 618 695 1.1E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 SUPERFAMILY SSF54791 556 641 4.55E-24 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 Gene3D G3DSA:3.30.230.70 311 544 2.3E-88 T 06-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 Gene3D G3DSA:3.30.230.70 6 225 5.1E-91 T 06-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 Gene3D G3DSA:1.10.10.400 230 310 1.1E-28 T 06-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 Pfam PF00013 KH domain 559 614 6.0E-10 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 SUPERFAMILY SSF50249 621 697 1.14E-20 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 SMART SM00316 621 691 5.7E-25 T 06-07-2017 IPR022967 RNA-binding domain, S1 GTHT12_RS06580 24fb2dd4d4d0e5f2daad5322ed85b213 722 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 241 321 5.6E-16 T 06-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 GTHT12_RS01900 18ef8a00db955778a725a6b51e0d68dd 409 SUPERFAMILY SSF53187 322 402 8.86E-65 T 06-07-2017 GTHT12_RS01900 18ef8a00db955778a725a6b51e0d68dd 409 SUPERFAMILY SSF53187 15 194 8.86E-65 T 06-07-2017 GTHT12_RS01900 18ef8a00db955778a725a6b51e0d68dd 409 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 85 94 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 GTHT12_RS01900 18ef8a00db955778a725a6b51e0d68dd 409 Pfam PF07687 Peptidase dimerisation domain 191 306 1.4E-21 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS01900 18ef8a00db955778a725a6b51e0d68dd 409 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 20 396 8.1E-86 T 06-07-2017 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase GTHT12_RS01900 18ef8a00db955778a725a6b51e0d68dd 409 Pfam PF01546 Peptidase family M20/M25/M40 86 400 1.6E-38 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 GTHT12_RS01900 18ef8a00db955778a725a6b51e0d68dd 409 Gene3D G3DSA:3.40.630.10 346 402 1.8E-69 T 06-07-2017 GTHT12_RS01900 18ef8a00db955778a725a6b51e0d68dd 409 Gene3D G3DSA:3.40.630.10 15 203 1.8E-69 T 06-07-2017 GTHT12_RS01900 18ef8a00db955778a725a6b51e0d68dd 409 Gene3D G3DSA:3.30.70.360 204 305 1.2E-24 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS01900 18ef8a00db955778a725a6b51e0d68dd 409 SUPERFAMILY SSF55031 194 317 4.93E-19 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS01900 18ef8a00db955778a725a6b51e0d68dd 409 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 121 159 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 GTHT12_RS07445 d6e5309b5d42a443f3242a53d5fd3e1c 242 Hamap MF_01968 NAD-dependent protein deacetylase [cobB]. 2 234 64.325 T 06-07-2017 IPR028628 Sirtuin, class U GO:0034979|GO:0051287 GTHT12_RS07445 d6e5309b5d42a443f3242a53d5fd3e1c 242 SUPERFAMILY SSF52467 3 237 3.72E-81 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS07445 d6e5309b5d42a443f3242a53d5fd3e1c 242 Pfam PF02146 Sir2 family 18 188 4.6E-49 T 06-07-2017 IPR003000 Sirtuin family GO:0070403 GTHT12_RS07445 d6e5309b5d42a443f3242a53d5fd3e1c 242 Gene3D G3DSA:3.40.50.1220 3 28 1.4E-45 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS07445 d6e5309b5d42a443f3242a53d5fd3e1c 242 Gene3D G3DSA:3.40.50.1220 164 238 1.4E-45 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS07445 d6e5309b5d42a443f3242a53d5fd3e1c 242 Gene3D G3DSA:3.40.50.1220 79 116 1.4E-45 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS07445 d6e5309b5d42a443f3242a53d5fd3e1c 242 Gene3D G3DSA:3.30.1600.10 117 157 8.3E-24 T 06-07-2017 IPR026591 Sirtuin family, catalytic core small domain GTHT12_RS07445 d6e5309b5d42a443f3242a53d5fd3e1c 242 Gene3D G3DSA:3.30.1600.10 29 67 8.3E-24 T 06-07-2017 IPR026591 Sirtuin family, catalytic core small domain GTHT12_RS18155 bb4ed958dbeb354523ee5516cf15bdf1 78 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 24 77 9.0E-25 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS18155 bb4ed958dbeb354523ee5516cf15bdf1 78 TIGRFAM TIGR00165 S18: ribosomal protein bS18 10 77 1.8E-38 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS18155 bb4ed958dbeb354523ee5516cf15bdf1 78 Gene3D G3DSA:4.10.640.10 12 77 8.0E-37 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS18155 bb4ed958dbeb354523ee5516cf15bdf1 78 ProSitePatterns PS00057 Ribosomal protein S18 signature. 25 48 - T 06-07-2017 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS18155 bb4ed958dbeb354523ee5516cf15bdf1 78 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 6 77 22.858 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS18155 bb4ed958dbeb354523ee5516cf15bdf1 78 SUPERFAMILY SSF46911 5 77 6.28E-32 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS18155 bb4ed958dbeb354523ee5516cf15bdf1 78 Pfam PF01084 Ribosomal protein S18 22 72 3.8E-29 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS18155 bb4ed958dbeb354523ee5516cf15bdf1 78 PRINTS PR00974 Ribosomal protein S18 family signature 32 42 5.9E-22 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS18155 bb4ed958dbeb354523ee5516cf15bdf1 78 PRINTS PR00974 Ribosomal protein S18 family signature 50 64 5.9E-22 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS18155 bb4ed958dbeb354523ee5516cf15bdf1 78 PRINTS PR00974 Ribosomal protein S18 family signature 64 74 5.9E-22 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS18155 bb4ed958dbeb354523ee5516cf15bdf1 78 PRINTS PR00974 Ribosomal protein S18 family signature 42 49 5.9E-22 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS05350 bceb8446d176b863b26bfb66f4d02137 285 Gene3D G3DSA:2.30.24.10 6 58 6.7E-22 T 06-07-2017 IPR004341 CAT RNA-binding domain GO:0003723 GTHT12_RS05350 bceb8446d176b863b26bfb66f4d02137 285 Pfam PF00874 PRD domain 80 167 7.9E-25 T 06-07-2017 IPR011608 PRD domain GO:0006355 GTHT12_RS05350 bceb8446d176b863b26bfb66f4d02137 285 Pfam PF00874 PRD domain 185 275 2.6E-20 T 06-07-2017 IPR011608 PRD domain GO:0006355 GTHT12_RS05350 bceb8446d176b863b26bfb66f4d02137 285 SMART SM01061 5 63 3.1E-29 T 06-07-2017 IPR004341 CAT RNA-binding domain GO:0003723 GTHT12_RS05350 bceb8446d176b863b26bfb66f4d02137 285 SUPERFAMILY SSF63520 59 171 2.75E-30 T 06-07-2017 IPR011608 PRD domain GO:0006355 GTHT12_RS05350 bceb8446d176b863b26bfb66f4d02137 285 SUPERFAMILY SSF63520 178 276 3.79E-25 T 06-07-2017 IPR011608 PRD domain GO:0006355 GTHT12_RS05350 bceb8446d176b863b26bfb66f4d02137 285 SUPERFAMILY SSF50151 5 57 3.27E-15 T 06-07-2017 IPR004341 CAT RNA-binding domain GO:0003723 GTHT12_RS05350 bceb8446d176b863b26bfb66f4d02137 285 Pfam PF03123 CAT RNA binding domain 6 61 5.2E-23 T 06-07-2017 IPR004341 CAT RNA-binding domain GO:0003723 GTHT12_RS05350 bceb8446d176b863b26bfb66f4d02137 285 Gene3D G3DSA:1.10.1790.10 70 170 9.6E-29 T 06-07-2017 IPR011608 PRD domain GO:0006355 GTHT12_RS05350 bceb8446d176b863b26bfb66f4d02137 285 Gene3D G3DSA:1.10.1790.10 176 279 2.2E-29 T 06-07-2017 IPR011608 PRD domain GO:0006355 GTHT12_RS14305 e5404891f57a82bb97ae7729aab33ee6 435 Pfam PF00571 CBS domain 219 245 2.8E-5 T 06-07-2017 IPR000644 CBS domain GTHT12_RS14305 e5404891f57a82bb97ae7729aab33ee6 435 Pfam PF00571 CBS domain 253 307 4.0E-8 T 06-07-2017 IPR000644 CBS domain GTHT12_RS14305 e5404891f57a82bb97ae7729aab33ee6 435 SUPERFAMILY SSF54631 182 307 7.71E-31 T 06-07-2017 GTHT12_RS14305 e5404891f57a82bb97ae7729aab33ee6 435 SUPERFAMILY SSF75138 72 185 6.93E-29 T 06-07-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like GTHT12_RS14305 e5404891f57a82bb97ae7729aab33ee6 435 Gene3D G3DSA:3.10.580.10 187 314 5.0E-31 T 06-07-2017 GTHT12_RS14305 e5404891f57a82bb97ae7729aab33ee6 435 Pfam PF07085 DRTGG domain 76 178 2.3E-31 T 06-07-2017 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 GTHT12_RS14305 e5404891f57a82bb97ae7729aab33ee6 435 SMART SM00116 200 248 1.7 T 06-07-2017 IPR000644 CBS domain GTHT12_RS14305 e5404891f57a82bb97ae7729aab33ee6 435 SMART SM00116 259 307 4.0E-9 T 06-07-2017 IPR000644 CBS domain GTHT12_RS14305 e5404891f57a82bb97ae7729aab33ee6 435 Pfam PF03061 Thioesterase superfamily 350 420 9.4E-12 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 GTHT12_RS14305 e5404891f57a82bb97ae7729aab33ee6 435 Gene3D G3DSA:1.10.10.10 7 64 1.4E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS14305 e5404891f57a82bb97ae7729aab33ee6 435 SUPERFAMILY SSF46785 5 54 2.09E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS14305 e5404891f57a82bb97ae7729aab33ee6 435 SUPERFAMILY SSF54637 302 429 9.06E-20 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS14305 e5404891f57a82bb97ae7729aab33ee6 435 Gene3D G3DSA:3.40.1390.20 66 186 6.7E-46 T 06-07-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like GTHT12_RS14305 e5404891f57a82bb97ae7729aab33ee6 435 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 58 1.5E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS14305 e5404891f57a82bb97ae7729aab33ee6 435 Gene3D G3DSA:3.10.129.10 319 430 1.1E-12 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS11120 fa9c1c044b1329eb9ce3322a954ebc76 323 SUPERFAMILY SSF51658 1 305 5.25E-51 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain GTHT12_RS11120 fa9c1c044b1329eb9ce3322a954ebc76 323 Pfam PF07582 AP endonuclease family 2 C terminus 270 323 6.2E-21 T 06-07-2017 IPR011418 AP endonuclease, family 2, C-terminal GTHT12_RS11120 fa9c1c044b1329eb9ce3322a954ebc76 323 Gene3D G3DSA:3.20.20.150 1 322 1.3E-72 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain GTHT12_RS11120 fa9c1c044b1329eb9ce3322a954ebc76 323 Pfam PF01261 Xylose isomerase-like TIM barrel 19 239 1.8E-30 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain GTHT12_RS11650 c4533ef1d61c9ab84fa4c9458ad9d7d7 339 Pfam PF00591 Glycosyl transferase family, a/b domain 72 323 1.1E-95 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 GTHT12_RS11650 c4533ef1d61c9ab84fa4c9458ad9d7d7 339 SUPERFAMILY SSF52418 73 332 1.83E-89 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 GTHT12_RS11650 c4533ef1d61c9ab84fa4c9458ad9d7d7 339 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 6 331 3.9E-124 T 06-07-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 GTHT12_RS11650 c4533ef1d61c9ab84fa4c9458ad9d7d7 339 Gene3D G3DSA:3.40.1030.10 73 149 1.4E-86 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 GTHT12_RS11650 c4533ef1d61c9ab84fa4c9458ad9d7d7 339 Gene3D G3DSA:3.40.1030.10 184 332 1.4E-86 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 GTHT12_RS11650 c4533ef1d61c9ab84fa4c9458ad9d7d7 339 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 4 333 38.909 T 06-07-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 GTHT12_RS11650 c4533ef1d61c9ab84fa4c9458ad9d7d7 339 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 64 1.3E-19 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 GTHT12_RS11650 c4533ef1d61c9ab84fa4c9458ad9d7d7 339 Gene3D G3DSA:1.20.970.10 1 64 3.2E-37 T 06-07-2017 GTHT12_RS11650 c4533ef1d61c9ab84fa4c9458ad9d7d7 339 Gene3D G3DSA:1.20.970.10 150 183 3.2E-37 T 06-07-2017 GTHT12_RS11650 c4533ef1d61c9ab84fa4c9458ad9d7d7 339 SUPERFAMILY SSF47648 2 68 1.44E-18 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 GTHT12_RS13160 9a924ee16417a4b48ca2bd9bcfe10f97 372 TIGRFAM TIGR01441 GPR: GPR endopeptidase 10 372 1.6E-176 T 06-07-2017 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 GTHT12_RS13160 9a924ee16417a4b48ca2bd9bcfe10f97 372 Gene3D G3DSA:3.40.50.1450 2 271 5.4E-148 T 06-07-2017 IPR023430 Peptidase HybD-like domain GTHT12_RS13160 9a924ee16417a4b48ca2bd9bcfe10f97 372 Gene3D G3DSA:3.40.50.1450 305 372 5.4E-148 T 06-07-2017 IPR023430 Peptidase HybD-like domain GTHT12_RS13160 9a924ee16417a4b48ca2bd9bcfe10f97 372 ProDom PD041835 PROTEASE GERMINATION HYDROLASE SPORE GPR ENDOPEPTIDASE PROTEINASE ZYMOGEN PRECURSOR PEPTIDASE 10 372 0.0 T 06-07-2017 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 GTHT12_RS13160 9a924ee16417a4b48ca2bd9bcfe10f97 372 Pfam PF03418 Germination protease 17 371 1.2E-190 T 06-07-2017 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 GTHT12_RS13160 9a924ee16417a4b48ca2bd9bcfe10f97 372 SUPERFAMILY SSF53163 3 372 1.29E-127 T 06-07-2017 IPR023430 Peptidase HybD-like domain GTHT12_RS13160 9a924ee16417a4b48ca2bd9bcfe10f97 372 Hamap MF_00626 Germination protease [gpr]. 1 372 159.528 T 06-07-2017 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 GTHT12_RS13160 9a924ee16417a4b48ca2bd9bcfe10f97 372 PIRSF PIRSF019549 3 372 8.5E-185 T 06-07-2017 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 GTHT12_RS14080 914a9d8d41255bd162e01b155d7a8720 117 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 6 111 1.8E-26 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 GTHT12_RS14080 914a9d8d41255bd162e01b155d7a8720 117 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 4 116 18.55 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 GTHT12_RS14080 914a9d8d41255bd162e01b155d7a8720 117 TIGRFAM TIGR00494 crcB: protein CrcB 6 112 9.6E-25 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 GTHT12_RS03900 1e8c88f7b5d3019043166285a9be8192 424 Gene3D G3DSA:3.40.190.10 45 169 1.3E-25 T 06-07-2017 GTHT12_RS03900 1e8c88f7b5d3019043166285a9be8192 424 SUPERFAMILY SSF53850 46 413 3.31E-90 T 06-07-2017 GTHT12_RS03900 1e8c88f7b5d3019043166285a9be8192 424 Gene3D G3DSA:3.40.190.10 170 348 2.1E-52 T 06-07-2017 GTHT12_RS03900 1e8c88f7b5d3019043166285a9be8192 424 PRINTS PR00181 Maltose binding protein signature 87 105 4.6E-7 T 06-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 GTHT12_RS03900 1e8c88f7b5d3019043166285a9be8192 424 PRINTS PR00181 Maltose binding protein signature 377 396 4.6E-7 T 06-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 GTHT12_RS03900 1e8c88f7b5d3019043166285a9be8192 424 PRINTS PR00181 Maltose binding protein signature 167 186 4.6E-7 T 06-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 GTHT12_RS03900 1e8c88f7b5d3019043166285a9be8192 424 PRINTS PR00181 Maltose binding protein signature 251 270 4.6E-7 T 06-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 GTHT12_RS03900 1e8c88f7b5d3019043166285a9be8192 424 PRINTS PR00181 Maltose binding protein signature 146 165 4.6E-7 T 06-07-2017 IPR006060 Maltose binding protein GO:0005363|GO:0015768 GTHT12_RS03900 1e8c88f7b5d3019043166285a9be8192 424 Pfam PF13416 Bacterial extracellular solute-binding protein 64 363 5.9E-50 T 06-07-2017 GTHT12_RS17420 533fae84463cebb8277e0d853fe03260 523 Pfam PF00361 Proton-conducting membrane transporter 137 427 2.7E-63 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17420 533fae84463cebb8277e0d853fe03260 523 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 4 519 5.7E-131 T 06-07-2017 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17420 533fae84463cebb8277e0d853fe03260 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 342 361 1.5E-32 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17420 533fae84463cebb8277e0d853fe03260 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 143 162 1.5E-32 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17420 533fae84463cebb8277e0d853fe03260 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 394 420 1.5E-32 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17420 533fae84463cebb8277e0d853fe03260 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 173 197 1.5E-32 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17420 533fae84463cebb8277e0d853fe03260 523 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 254 278 1.5E-32 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS11520 b9e616e67e0b4b5818d86bcecf1b7e24 127 Pfam PF02261 Aspartate decarboxylase 1 114 8.4E-52 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 GTHT12_RS11520 b9e616e67e0b4b5818d86bcecf1b7e24 127 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 126 5.9E-57 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 GTHT12_RS11520 b9e616e67e0b4b5818d86bcecf1b7e24 127 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 127 72.207 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 GTHT12_RS11520 b9e616e67e0b4b5818d86bcecf1b7e24 127 Gene3D G3DSA:2.40.40.20 1 122 8.3E-56 T 06-07-2017 GTHT12_RS11520 b9e616e67e0b4b5818d86bcecf1b7e24 127 SUPERFAMILY SSF50692 1 120 1.99E-49 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain GTHT12_RS11520 b9e616e67e0b4b5818d86bcecf1b7e24 127 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 95 8.0E-45 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 GTHT12_RS11520 b9e616e67e0b4b5818d86bcecf1b7e24 127 PIRSF PIRSF006246 1 126 2.3E-52 T 06-07-2017 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 GTHT12_RS16410 0353e64867f783b1c49a4144dcf07b12 544 Pfam PF00877 NlpC/P60 family 440 542 1.3E-29 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain GTHT12_RS16410 0353e64867f783b1c49a4144dcf07b12 544 Gene3D G3DSA:3.90.1720.10 429 544 3.0E-42 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain GTHT12_RS16410 0353e64867f783b1c49a4144dcf07b12 544 SUPERFAMILY SSF54001 430 544 3.14E-40 T 06-07-2017 GTHT12_RS16410 0353e64867f783b1c49a4144dcf07b12 544 SUPERFAMILY SSF47090 346 410 2.67E-17 T 06-07-2017 IPR002477 Peptidoglycan binding-like GTHT12_RS16410 0353e64867f783b1c49a4144dcf07b12 544 SUPERFAMILY SSF47090 30 93 8.79E-19 T 06-07-2017 IPR002477 Peptidoglycan binding-like GTHT12_RS16410 0353e64867f783b1c49a4144dcf07b12 544 SUPERFAMILY SSF47090 177 244 4.84E-18 T 06-07-2017 IPR002477 Peptidoglycan binding-like GTHT12_RS16410 0353e64867f783b1c49a4144dcf07b12 544 SUPERFAMILY SSF47090 95 170 1.88E-22 T 06-07-2017 IPR002477 Peptidoglycan binding-like GTHT12_RS16410 0353e64867f783b1c49a4144dcf07b12 544 Gene3D G3DSA:1.10.101.10 263 333 2.4E-18 T 06-07-2017 IPR002477 Peptidoglycan binding-like GTHT12_RS16410 0353e64867f783b1c49a4144dcf07b12 544 Gene3D G3DSA:1.10.101.10 28 94 4.0E-20 T 06-07-2017 IPR002477 Peptidoglycan binding-like GTHT12_RS16410 0353e64867f783b1c49a4144dcf07b12 544 Gene3D G3DSA:1.10.101.10 348 410 7.9E-18 T 06-07-2017 IPR002477 Peptidoglycan binding-like GTHT12_RS16410 0353e64867f783b1c49a4144dcf07b12 544 Gene3D G3DSA:1.10.101.10 177 249 1.6E-18 T 06-07-2017 IPR002477 Peptidoglycan binding-like GTHT12_RS16410 0353e64867f783b1c49a4144dcf07b12 544 Gene3D G3DSA:1.10.101.10 98 171 2.8E-22 T 06-07-2017 IPR002477 Peptidoglycan binding-like GTHT12_RS16410 0353e64867f783b1c49a4144dcf07b12 544 SUPERFAMILY SSF47090 262 327 4.24E-17 T 06-07-2017 IPR002477 Peptidoglycan binding-like GTHT12_RS16410 0353e64867f783b1c49a4144dcf07b12 544 Pfam PF01471 Putative peptidoglycan binding domain 270 324 2.7E-17 T 06-07-2017 IPR002477 Peptidoglycan binding-like GTHT12_RS16410 0353e64867f783b1c49a4144dcf07b12 544 Pfam PF01471 Putative peptidoglycan binding domain 353 410 1.0E-16 T 06-07-2017 IPR002477 Peptidoglycan binding-like GTHT12_RS16410 0353e64867f783b1c49a4144dcf07b12 544 Pfam PF01471 Putative peptidoglycan binding domain 187 242 5.4E-17 T 06-07-2017 IPR002477 Peptidoglycan binding-like GTHT12_RS16410 0353e64867f783b1c49a4144dcf07b12 544 Pfam PF01471 Putative peptidoglycan binding domain 37 92 1.3E-17 T 06-07-2017 IPR002477 Peptidoglycan binding-like GTHT12_RS16410 0353e64867f783b1c49a4144dcf07b12 544 Pfam PF01471 Putative peptidoglycan binding domain 107 164 2.7E-20 T 06-07-2017 IPR002477 Peptidoglycan binding-like GTHT12_RS10280 47ffad8bcb4d6bbc1203f23baa7cdb07 466 Pfam PF13416 Bacterial extracellular solute-binding protein 68 397 4.4E-31 T 06-07-2017 GTHT12_RS10280 47ffad8bcb4d6bbc1203f23baa7cdb07 466 SUPERFAMILY SSF53850 26 464 2.03E-78 T 06-07-2017 GTHT12_RS10280 47ffad8bcb4d6bbc1203f23baa7cdb07 466 Gene3D G3DSA:3.40.190.10 47 166 8.5E-41 T 06-07-2017 GTHT12_RS10280 47ffad8bcb4d6bbc1203f23baa7cdb07 466 Gene3D G3DSA:3.40.190.10 343 410 8.5E-41 T 06-07-2017 GTHT12_RS01755 1e3f2260bec27964032ae1767dd80fa8 232 Gene3D G3DSA:1.10.10.10 128 227 4.2E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS01755 1e3f2260bec27964032ae1767dd80fa8 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 3.1E-20 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS01755 1e3f2260bec27964032ae1767dd80fa8 232 SMART SM00862 149 225 2.7E-18 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS01755 1e3f2260bec27964032ae1767dd80fa8 232 Gene3D G3DSA:3.40.50.2300 2 122 4.2E-39 T 06-07-2017 GTHT12_RS01755 1e3f2260bec27964032ae1767dd80fa8 232 Pfam PF00072 Response regulator receiver domain 6 113 1.2E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS01755 1e3f2260bec27964032ae1767dd80fa8 232 SUPERFAMILY SSF52172 1 178 1.08E-40 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS01755 1e3f2260bec27964032ae1767dd80fa8 232 SMART SM00448 4 113 8.7E-43 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS06770 4969b23450f83ca6e2c486789120e9f4 645 SMART SM01340 208 326 9.3E-58 T 06-07-2017 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 GTHT12_RS06770 4969b23450f83ca6e2c486789120e9f4 645 SMART SM00853 459 601 1.5E-51 T 06-07-2017 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 GTHT12_RS06770 4969b23450f83ca6e2c486789120e9f4 645 SUPERFAMILY SSF118116 455 643 3.53E-53 T 06-07-2017 GTHT12_RS06770 4969b23450f83ca6e2c486789120e9f4 645 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 112 3.2E-11 T 06-07-2017 GTHT12_RS06770 4969b23450f83ca6e2c486789120e9f4 645 SUPERFAMILY SSF54211 190 326 5.69E-38 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS06770 4969b23450f83ca6e2c486789120e9f4 645 SUPERFAMILY SSF55874 3 213 1.13E-52 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS06770 4969b23450f83ca6e2c486789120e9f4 645 Gene3D G3DSA:3.30.565.10 3 202 9.8E-72 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS06770 4969b23450f83ca6e2c486789120e9f4 645 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 209 325 2.7E-38 T 06-07-2017 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 GTHT12_RS06770 4969b23450f83ca6e2c486789120e9f4 645 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 06-07-2017 IPR014762 DNA mismatch repair, conserved site GTHT12_RS06770 4969b23450f83ca6e2c486789120e9f4 645 Gene3D G3DSA:3.30.230.10 203 325 8.7E-40 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GTHT12_RS06770 4969b23450f83ca6e2c486789120e9f4 645 Pfam PF08676 MutL C terminal dimerisation domain 459 601 7.1E-45 T 06-07-2017 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 GTHT12_RS06770 4969b23450f83ca6e2c486789120e9f4 645 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 306 5.7E-101 T 06-07-2017 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 GTHT12_RS06770 4969b23450f83ca6e2c486789120e9f4 645 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 641 27.811 T 06-07-2017 IPR020667 DNA mismatch repair protein, MutL GO:0006298 GTHT12_RS09745 1e7dad464b09a7523ad49a20254281af 237 SUPERFAMILY SSF46785 1 70 1.11E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS09745 1e7dad464b09a7523ad49a20254281af 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 2.2E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS09745 1e7dad464b09a7523ad49a20254281af 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 2.2E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS09745 1e7dad464b09a7523ad49a20254281af 237 Pfam PF07702 UTRA domain 91 228 4.6E-37 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 GTHT12_RS09745 1e7dad464b09a7523ad49a20254281af 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 3.6E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS09745 1e7dad464b09a7523ad49a20254281af 237 Gene3D G3DSA:3.40.1410.10 61 236 3.6E-59 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain GTHT12_RS09745 1e7dad464b09a7523ad49a20254281af 237 Gene3D G3DSA:1.10.10.10 1 60 2.4E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS09745 1e7dad464b09a7523ad49a20254281af 237 SMART SM00345 7 66 3.2E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS09745 1e7dad464b09a7523ad49a20254281af 237 SMART SM00866 90 229 1.3E-42 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 GTHT12_RS09745 1e7dad464b09a7523ad49a20254281af 237 SUPERFAMILY SSF64288 82 232 9.11E-48 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain GTHT12_RS13575 560077429ece1707ef2fc1987dfabbf0 522 TIGRFAM TIGR02899 spore_safA: spore coat assembly protein SafA 6 49 2.6E-24 T 06-07-2017 IPR014248 Spore coat assembly protein SafA GTHT12_RS13575 560077429ece1707ef2fc1987dfabbf0 522 Pfam PF01476 LysM domain 4 48 2.4E-15 T 06-07-2017 IPR018392 LysM domain GTHT12_RS13575 560077429ece1707ef2fc1987dfabbf0 522 SUPERFAMILY SSF54106 2 48 1.83E-12 T 06-07-2017 IPR018392 LysM domain GTHT12_RS13575 560077429ece1707ef2fc1987dfabbf0 522 SMART SM00257 3 48 9.7E-19 T 06-07-2017 IPR018392 LysM domain GTHT12_RS13575 560077429ece1707ef2fc1987dfabbf0 522 Gene3D G3DSA:3.10.350.10 2 48 9.7E-18 T 06-07-2017 IPR018392 LysM domain GTHT12_RS18125 4316c13eac261e3e9d4593589f5cb6d2 237 Gene3D G3DSA:3.40.50.2300 2 123 3.8E-45 T 06-07-2017 GTHT12_RS18125 4316c13eac261e3e9d4593589f5cb6d2 237 Gene3D G3DSA:1.10.10.10 130 233 2.3E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS18125 4316c13eac261e3e9d4593589f5cb6d2 237 Pfam PF00072 Response regulator receiver domain 5 114 1.2E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS18125 4316c13eac261e3e9d4593589f5cb6d2 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 230 7.8E-28 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS18125 4316c13eac261e3e9d4593589f5cb6d2 237 SMART SM00862 154 230 8.2E-29 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS18125 4316c13eac261e3e9d4593589f5cb6d2 237 SMART SM00448 3 113 4.3E-48 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS18125 4316c13eac261e3e9d4593589f5cb6d2 237 SUPERFAMILY SSF46894 130 231 4.25E-32 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GTHT12_RS18125 4316c13eac261e3e9d4593589f5cb6d2 237 SUPERFAMILY SSF52172 2 128 8.25E-45 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS14340 0762b649b6f8283cb8ee370ffd6aa7c9 406 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 116 127 - T 06-07-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GTHT12_RS14340 0762b649b6f8283cb8ee370ffd6aa7c9 406 TIGRFAM TIGR00032 argG: argininosuccinate synthase 5 393 6.7E-176 T 06-07-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GTHT12_RS14340 0762b649b6f8283cb8ee370ffd6aa7c9 406 Gene3D G3DSA:3.90.1260.10 173 398 1.8E-92 T 06-07-2017 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GTHT12_RS14340 0762b649b6f8283cb8ee370ffd6aa7c9 406 SUPERFAMILY SSF52402 1 170 2.16E-48 T 06-07-2017 GTHT12_RS14340 0762b649b6f8283cb8ee370ffd6aa7c9 406 SUPERFAMILY SSF69864 170 397 7.46E-94 T 06-07-2017 GTHT12_RS14340 0762b649b6f8283cb8ee370ffd6aa7c9 406 Hamap MF_00005 Argininosuccinate synthase [argG]. 3 396 55.936 T 06-07-2017 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GTHT12_RS14340 0762b649b6f8283cb8ee370ffd6aa7c9 406 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 9 17 - T 06-07-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GTHT12_RS14340 0762b649b6f8283cb8ee370ffd6aa7c9 406 Pfam PF00764 Arginosuccinate synthase 7 391 3.1E-183 T 06-07-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GTHT12_RS14340 0762b649b6f8283cb8ee370ffd6aa7c9 406 Gene3D G3DSA:3.40.50.620 1 172 6.0E-60 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS07905 96839984efcc5ddbd651799d12a661d7 766 SUPERFAMILY SSF52540 69 124 1.06E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07905 96839984efcc5ddbd651799d12a661d7 766 SUPERFAMILY SSF52540 305 445 1.06E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07905 96839984efcc5ddbd651799d12a661d7 766 SUPERFAMILY SSF52540 37 242 5.46E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07905 96839984efcc5ddbd651799d12a661d7 766 Gene3D G3DSA:3.40.50.300 271 419 2.6E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07905 96839984efcc5ddbd651799d12a661d7 766 SMART SM00490 306 389 4.6E-12 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS07905 96839984efcc5ddbd651799d12a661d7 766 SMART SM00487 51 255 5.4E-34 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain GTHT12_RS07905 96839984efcc5ddbd651799d12a661d7 766 Pfam PF00270 DEAD/DEAH box helicase 58 227 1.9E-30 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 GTHT12_RS07905 96839984efcc5ddbd651799d12a661d7 766 Gene3D G3DSA:3.40.50.300 38 241 2.8E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07905 96839984efcc5ddbd651799d12a661d7 766 Pfam PF09369 Domain of unknown function (DUF1998) 650 728 1.5E-19 T 06-07-2017 IPR018973 DEAD/DEAH-box helicase, putative GTHT12_RS07905 96839984efcc5ddbd651799d12a661d7 766 Pfam PF00271 Helicase conserved C-terminal domain 286 388 6.1E-11 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS16075 22af1da30b504e47195295e14ba77b49 481 Gene3D G3DSA:2.30.42.10 120 195 5.3E-28 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS16075 22af1da30b504e47195295e14ba77b49 481 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 66 383 4.6E-120 T 06-07-2017 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 GTHT12_RS16075 22af1da30b504e47195295e14ba77b49 481 Gene3D G3DSA:1.10.101.10 405 457 9.5E-15 T 06-07-2017 IPR002477 Peptidoglycan binding-like GTHT12_RS16075 22af1da30b504e47195295e14ba77b49 481 SMART SM00228 114 185 2.8E-19 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS16075 22af1da30b504e47195295e14ba77b49 481 Pfam PF03572 Peptidase family S41 215 377 1.3E-51 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 GTHT12_RS16075 22af1da30b504e47195295e14ba77b49 481 Gene3D G3DSA:3.90.226.10 196 404 2.2E-64 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS16075 22af1da30b504e47195295e14ba77b49 481 SMART SM00245 187 378 2.0E-70 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 GTHT12_RS16075 22af1da30b504e47195295e14ba77b49 481 Gene3D G3DSA:3.30.750.44 59 119 9.5E-9 T 06-07-2017 GTHT12_RS16075 22af1da30b504e47195295e14ba77b49 481 SUPERFAMILY SSF52096 54 132 3.81E-73 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS16075 22af1da30b504e47195295e14ba77b49 481 SUPERFAMILY SSF52096 209 385 3.81E-73 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS16075 22af1da30b504e47195295e14ba77b49 481 SUPERFAMILY SSF50156 85 204 4.05E-23 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS16075 22af1da30b504e47195295e14ba77b49 481 Pfam PF13180 PDZ domain 115 194 1.9E-14 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS16075 22af1da30b504e47195295e14ba77b49 481 SUPERFAMILY SSF47090 388 457 7.85E-18 T 06-07-2017 IPR002477 Peptidoglycan binding-like GTHT12_RS16075 22af1da30b504e47195295e14ba77b49 481 Pfam PF01471 Putative peptidoglycan binding domain 400 455 9.7E-16 T 06-07-2017 IPR002477 Peptidoglycan binding-like GTHT12_RS17250 4ec52730b137f200a2acd236c0fd9361 411 Pfam PF00534 Glycosyl transferases group 1 222 382 4.5E-27 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 GTHT12_RS17250 4ec52730b137f200a2acd236c0fd9361 411 Gene3D G3DSA:3.40.50.2000 217 382 1.2E-18 T 06-07-2017 GTHT12_RS17250 4ec52730b137f200a2acd236c0fd9361 411 SUPERFAMILY SSF53756 31 406 3.04E-59 T 06-07-2017 GTHT12_RS17810 5cd6037d300ff6154fa0ef060be56197 229 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 57 66 - T 06-07-2017 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 GTHT12_RS17810 5cd6037d300ff6154fa0ef060be56197 229 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 6 212 5.6E-83 T 06-07-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 GTHT12_RS17810 5cd6037d300ff6154fa0ef060be56197 229 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 5 220 41.29 T 06-07-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 GTHT12_RS17810 5cd6037d300ff6154fa0ef060be56197 229 Gene3D G3DSA:3.40.470.10 4 221 5.3E-99 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 GTHT12_RS17810 5cd6037d300ff6154fa0ef060be56197 229 SMART SM00987 49 209 5.1E-38 T 06-07-2017 GTHT12_RS17810 5cd6037d300ff6154fa0ef060be56197 229 Pfam PF03167 Uracil DNA glycosylase superfamily 51 208 6.3E-25 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 GTHT12_RS17810 5cd6037d300ff6154fa0ef060be56197 229 SUPERFAMILY SSF52141 3 221 1.05E-95 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 GTHT12_RS17810 5cd6037d300ff6154fa0ef060be56197 229 SMART SM00986 49 209 5.1E-38 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 GTHT12_RS03540 55ae34aeee0309b85ab63c95922f9506 370 Pfam PF00005 ABC transporter 21 162 1.6E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS03540 55ae34aeee0309b85ab63c95922f9506 370 Gene3D G3DSA:2.40.50.100 240 285 2.9E-25 T 06-07-2017 GTHT12_RS03540 55ae34aeee0309b85ab63c95922f9506 370 Gene3D G3DSA:2.40.50.100 350 365 2.9E-25 T 06-07-2017 GTHT12_RS03540 55ae34aeee0309b85ab63c95922f9506 370 Gene3D G3DSA:2.40.50.140 286 349 2.6E-15 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS03540 55ae34aeee0309b85ab63c95922f9506 370 SMART SM00382 29 212 4.7E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS03540 55ae34aeee0309b85ab63c95922f9506 370 Gene3D G3DSA:3.40.50.300 6 231 6.8E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03540 55ae34aeee0309b85ab63c95922f9506 370 SUPERFAMILY SSF50331 237 365 1.56E-29 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal GTHT12_RS03540 55ae34aeee0309b85ab63c95922f9506 370 SUPERFAMILY SSF52540 4 243 1.68E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03540 55ae34aeee0309b85ab63c95922f9506 370 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS03540 55ae34aeee0309b85ab63c95922f9506 370 Pfam PF08402 TOBE domain 281 356 1.8E-7 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 GTHT12_RS06620 409971aa7f69f006814b18f7079df9ac 291 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 135 165 - T 06-07-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS06620 409971aa7f69f006814b18f7079df9ac 291 PIRSF PIRSF001365 2 291 1.7E-101 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 GTHT12_RS06620 409971aa7f69f006814b18f7079df9ac 291 SUPERFAMILY SSF51569 4 289 2.2E-107 T 06-07-2017 GTHT12_RS06620 409971aa7f69f006814b18f7079df9ac 291 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 40 57 - T 06-07-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS06620 409971aa7f69f006814b18f7079df9ac 291 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 3 289 65.718 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS06620 409971aa7f69f006814b18f7079df9ac 291 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 7 288 2.0E-115 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS06620 409971aa7f69f006814b18f7079df9ac 291 SMART SM01130 3 291 2.2E-145 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 GTHT12_RS06620 409971aa7f69f006814b18f7079df9ac 291 Gene3D G3DSA:3.20.20.70 3 290 2.9E-124 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS06620 409971aa7f69f006814b18f7079df9ac 291 Pfam PF00701 Dihydrodipicolinate synthetase family 4 289 1.8E-114 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 GTHT12_RS06620 409971aa7f69f006814b18f7079df9ac 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 8.2E-36 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 GTHT12_RS06620 409971aa7f69f006814b18f7079df9ac 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 8.2E-36 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 GTHT12_RS06620 409971aa7f69f006814b18f7079df9ac 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 8.2E-36 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 GTHT12_RS06620 409971aa7f69f006814b18f7079df9ac 291 PRINTS PR00146 Dihydrodipicolinate synthase signature 130 147 8.2E-36 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 GTHT12_RS06685 a5f067aa1df62f1a95dfd0361814c864 238 SUPERFAMILY SSF51735 3 237 3.26E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS06685 a5f067aa1df62f1a95dfd0361814c864 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 1.2E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS06685 a5f067aa1df62f1a95dfd0361814c864 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 1.2E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS06685 a5f067aa1df62f1a95dfd0361814c864 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 1.2E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS06685 a5f067aa1df62f1a95dfd0361814c864 238 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 237 4.6E-53 T 06-07-2017 GTHT12_RS06685 a5f067aa1df62f1a95dfd0361814c864 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 3.6E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS06685 a5f067aa1df62f1a95dfd0361814c864 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 220 3.6E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS06685 a5f067aa1df62f1a95dfd0361814c864 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 3.6E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS06685 a5f067aa1df62f1a95dfd0361814c864 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 3.6E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS06685 a5f067aa1df62f1a95dfd0361814c864 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 3.6E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS06685 a5f067aa1df62f1a95dfd0361814c864 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.6E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS06685 a5f067aa1df62f1a95dfd0361814c864 238 Gene3D G3DSA:3.40.50.720 3 238 1.4E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS05960 e18c3ca324300c278fc76afa9e3163ec 257 Pfam PF01479 S4 domain 182 227 8.9E-10 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS05960 e18c3ca324300c278fc76afa9e3163ec 257 SMART SM00363 181 238 4.4E-11 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS05960 e18c3ca324300c278fc76afa9e3163ec 257 SUPERFAMILY SSF55174 35 126 9.81E-36 T 06-07-2017 GTHT12_RS05960 e18c3ca324300c278fc76afa9e3163ec 257 SUPERFAMILY SSF55174 178 251 9.81E-36 T 06-07-2017 GTHT12_RS05960 e18c3ca324300c278fc76afa9e3163ec 257 Gene3D G3DSA:3.10.290.10 179 234 1.5E-15 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS08130 8565229983033db717327430f9a803b3 236 Gene3D G3DSA:3.40.50.1580 8 233 7.8E-85 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 GTHT12_RS08130 8565229983033db717327430f9a803b3 236 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 233 49.007 T 06-07-2017 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 GTHT12_RS08130 8565229983033db717327430f9a803b3 236 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 06-07-2017 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 GTHT12_RS08130 8565229983033db717327430f9a803b3 236 SUPERFAMILY SSF53167 3 234 9.69E-94 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 GTHT12_RS08130 8565229983033db717327430f9a803b3 236 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 231 1.8E-105 T 06-07-2017 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 GTHT12_RS08130 8565229983033db717327430f9a803b3 236 Pfam PF01048 Phosphorylase superfamily 16 221 2.9E-39 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 GTHT12_RS11425 75a69e0966814691d59bf31fdd75db28 224 Gene3D G3DSA:1.10.10.10 125 223 2.7E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS11425 75a69e0966814691d59bf31fdd75db28 224 SMART SM00862 147 222 5.2E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS11425 75a69e0966814691d59bf31fdd75db28 224 SMART SM00448 3 113 8.9E-44 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS11425 75a69e0966814691d59bf31fdd75db28 224 Gene3D G3DSA:3.40.50.2300 2 122 1.0E-40 T 06-07-2017 GTHT12_RS11425 75a69e0966814691d59bf31fdd75db28 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 222 1.2E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS11425 75a69e0966814691d59bf31fdd75db28 224 SUPERFAMILY SSF52172 4 178 7.24E-42 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS11425 75a69e0966814691d59bf31fdd75db28 224 Pfam PF00072 Response regulator receiver domain 5 114 7.8E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS18320 45b3aa4e934a1f1221f798c5e9d4f1ee 200 Pfam PF13411 MerR HTH family regulatory protein 4 73 4.4E-6 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS18320 45b3aa4e934a1f1221f798c5e9d4f1ee 200 Pfam PF13152 Protein of unknown function (DUF3967) 138 175 2.1E-5 T 06-07-2017 IPR025052 Domain of unknown function DUF3967 GTHT12_RS18320 45b3aa4e934a1f1221f798c5e9d4f1ee 200 SUPERFAMILY SSF46955 100 134 2.56E-8 T 06-07-2017 IPR009061 Putative DNA-binding domain GTHT12_RS18320 45b3aa4e934a1f1221f798c5e9d4f1ee 200 SUPERFAMILY SSF46955 4 73 2.56E-8 T 06-07-2017 IPR009061 Putative DNA-binding domain GTHT12_RS18320 45b3aa4e934a1f1221f798c5e9d4f1ee 200 Gene3D G3DSA:1.10.1660.10 4 128 4.9E-9 T 06-07-2017 GTHT12_RS18410 faade92c72738b2491a3cb5d4132b5b9 417 SUPERFAMILY SSF46689 48 133 2.33E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS18410 faade92c72738b2491a3cb5d4132b5b9 417 SUPERFAMILY SSF53098 148 312 3.41E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS18410 faade92c72738b2491a3cb5d4132b5b9 417 Pfam PF13565 Homeodomain-like domain 53 130 8.6E-11 T 06-07-2017 GTHT12_RS18410 faade92c72738b2491a3cb5d4132b5b9 417 Pfam PF09299 Mu transposase, C-terminal 332 383 3.4E-8 T 06-07-2017 IPR015378 Transposase-like, Mu, C-terminal GTHT12_RS18410 faade92c72738b2491a3cb5d4132b5b9 417 Pfam PF00665 Integrase core domain 154 269 2.8E-22 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS18410 faade92c72738b2491a3cb5d4132b5b9 417 Gene3D G3DSA:3.30.420.10 147 310 1.4E-36 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS15240 152dc9948d4b85cc5187e8bfe5dbc310 301 Gene3D G3DSA:2.40.50.90 99 196 7.9E-26 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold GTHT12_RS15240 152dc9948d4b85cc5187e8bfe5dbc310 301 SUPERFAMILY SSF50199 98 230 3.79E-27 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold GTHT12_RS15240 152dc9948d4b85cc5187e8bfe5dbc310 301 SMART SM00318 100 229 6.6E-23 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold GTHT12_RS15240 152dc9948d4b85cc5187e8bfe5dbc310 301 Pfam PF00565 Staphylococcal nuclease homologue 127 228 1.9E-16 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold GTHT12_RS07570 480e913b3b3492d3c5acf8214cf91f6d 245 SUPERFAMILY SSF55811 154 189 3.93E-10 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 GTHT12_RS07570 480e913b3b3492d3c5acf8214cf91f6d 245 SUPERFAMILY SSF55811 40 115 3.93E-10 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 GTHT12_RS07570 480e913b3b3492d3c5acf8214cf91f6d 245 Gene3D G3DSA:3.90.79.10 69 189 4.4E-9 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 GTHT12_RS10265 8e1445b61d78661de850d3e512ab3567 1044 Pfam PF09261 Alpha mannosidase middle domain 517 597 3.3E-26 T 06-07-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 GTHT12_RS10265 8e1445b61d78661de850d3e512ab3567 1044 Gene3D G3DSA:1.20.1270.50 520 620 1.3E-23 T 06-07-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 GTHT12_RS10265 8e1445b61d78661de850d3e512ab3567 1044 Gene3D G3DSA:3.20.110.10 186 519 3.1E-90 T 06-07-2017 IPR027291 Glycoside hydrolase 38/57, N-terminal domain GTHT12_RS10265 8e1445b61d78661de850d3e512ab3567 1044 SUPERFAMILY SSF74650 611 1042 2.51E-108 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 GTHT12_RS10265 8e1445b61d78661de850d3e512ab3567 1044 SUPERFAMILY SSF88713 232 515 2.67E-82 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 GTHT12_RS10265 8e1445b61d78661de850d3e512ab3567 1044 SUPERFAMILY SSF88688 516 622 5.56E-27 T 06-07-2017 IPR028995 Glycoside hydrolase families 57/38, central domain GTHT12_RS10265 8e1445b61d78661de850d3e512ab3567 1044 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 239 510 8.7E-86 T 06-07-2017 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0005975 GTHT12_RS10265 8e1445b61d78661de850d3e512ab3567 1044 Gene3D G3DSA:2.60.40.1180 621 682 2.4E-5 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta GTHT12_RS10265 8e1445b61d78661de850d3e512ab3567 1044 SMART SM00872 517 597 7.0E-34 T 06-07-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 GTHT12_RS10265 8e1445b61d78661de850d3e512ab3567 1044 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 623 1040 2.2E-94 T 06-07-2017 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0006013|GO:0015923 GTHT12_RS11470 47f9d4bfe79a04c3105fe294fcf5104e 896 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 95 638 7.3E-186 T 06-07-2017 GTHT12_RS11470 47f9d4bfe79a04c3105fe294fcf5104e 896 Gene3D G3DSA:3.40.710.10 263 691 1.8E-107 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS11470 47f9d4bfe79a04c3105fe294fcf5104e 896 Pfam PF00905 Penicillin binding protein transpeptidase domain 353 634 6.6E-46 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 GTHT12_RS11470 47f9d4bfe79a04c3105fe294fcf5104e 896 SUPERFAMILY SSF53955 74 284 2.78E-75 T 06-07-2017 IPR023346 Lysozyme-like domain GTHT12_RS11470 47f9d4bfe79a04c3105fe294fcf5104e 896 SUPERFAMILY SSF56601 296 692 1.73E-109 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS11470 47f9d4bfe79a04c3105fe294fcf5104e 896 SUPERFAMILY SSF56601 242 264 1.73E-109 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS11470 47f9d4bfe79a04c3105fe294fcf5104e 896 Gene3D G3DSA:2.60.40.10 698 780 4.0E-7 T 06-07-2017 IPR013783 Immunoglobulin-like fold GTHT12_RS11470 47f9d4bfe79a04c3105fe294fcf5104e 896 Pfam PF00912 Transglycosylase 85 260 8.5E-65 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 GTHT12_RS11470 47f9d4bfe79a04c3105fe294fcf5104e 896 Gene3D G3DSA:1.10.3810.10 86 262 6.7E-74 T 06-07-2017 GTHT12_RS11470 47f9d4bfe79a04c3105fe294fcf5104e 896 SUPERFAMILY SSF49265 701 779 7.98E-7 T 06-07-2017 IPR003961 Fibronectin type III GO:0005515 GTHT12_RS02500 9622295f7bbe18d796f7b4292c900388 350 Pfam PF01699 Sodium/calcium exchanger protein 27 178 4.4E-22 T 06-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 GTHT12_RS02500 9622295f7bbe18d796f7b4292c900388 350 Pfam PF01699 Sodium/calcium exchanger protein 205 342 8.2E-20 T 06-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 GTHT12_RS02500 9622295f7bbe18d796f7b4292c900388 350 TIGRFAM TIGR00378 cax: calcium/proton exchanger 12 348 1.5E-144 T 06-07-2017 IPR004798 Calcium/proton exchanger CAX GO:0006816|GO:0015369 GTHT12_RS02500 9622295f7bbe18d796f7b4292c900388 350 TIGRFAM TIGR00846 caca2: calcium/proton exchanger 11 347 8.5E-120 T 06-07-2017 IPR004713 Calcium/proton exchanger GO:0006812|GO:0008324|GO:0016021|GO:0055085 GTHT12_RS18590 889f472a046793bb3d8912d5e1dc0a20 706 Gene3D G3DSA:3.40.50.140 1 155 7.5E-46 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS18590 889f472a046793bb3d8912d5e1dc0a20 706 Pfam PF01751 Toprim domain 3 136 2.7E-17 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS18590 889f472a046793bb3d8912d5e1dc0a20 706 SMART SM00436 129 224 6.3E-38 T 06-07-2017 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 GTHT12_RS18590 889f472a046793bb3d8912d5e1dc0a20 706 Pfam PF01131 DNA topoisomerase 156 588 1.6E-107 T 06-07-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 GTHT12_RS18590 889f472a046793bb3d8912d5e1dc0a20 706 SMART SM00437 273 553 1.1E-70 T 06-07-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 GTHT12_RS18590 889f472a046793bb3d8912d5e1dc0a20 706 Gene3D G3DSA:1.10.460.10 477 602 1.3E-50 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 GTHT12_RS18590 889f472a046793bb3d8912d5e1dc0a20 706 Gene3D G3DSA:1.10.460.10 159 218 1.3E-50 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 GTHT12_RS18590 889f472a046793bb3d8912d5e1dc0a20 706 SMART SM00493 1 128 2.7E-20 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS18590 889f472a046793bb3d8912d5e1dc0a20 706 TIGRFAM TIGR01056 topB: DNA topoisomerase III 2 689 2.2E-192 T 06-07-2017 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 GTHT12_RS18590 889f472a046793bb3d8912d5e1dc0a20 706 Pfam PF13342 C-terminal repeat of topoisomerase 650 705 4.3E-17 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat GTHT12_RS18590 889f472a046793bb3d8912d5e1dc0a20 706 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 310 324 - T 06-07-2017 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 GTHT12_RS18590 889f472a046793bb3d8912d5e1dc0a20 706 Gene3D G3DSA:2.70.20.10 359 476 1.6E-33 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 GTHT12_RS18590 889f472a046793bb3d8912d5e1dc0a20 706 Gene3D G3DSA:2.70.20.10 219 252 1.6E-33 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 GTHT12_RS18590 889f472a046793bb3d8912d5e1dc0a20 706 SUPERFAMILY SSF56712 1 602 8.5E-168 T 06-07-2017 IPR023405 DNA topoisomerase, type IA, core domain GTHT12_RS18590 889f472a046793bb3d8912d5e1dc0a20 706 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 194 212 5.6E-23 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS18590 889f472a046793bb3d8912d5e1dc0a20 706 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 102 115 5.6E-23 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS18590 889f472a046793bb3d8912d5e1dc0a20 706 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 315 324 5.6E-23 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS18590 889f472a046793bb3d8912d5e1dc0a20 706 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 396 412 5.6E-23 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS18590 889f472a046793bb3d8912d5e1dc0a20 706 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 516 530 5.6E-23 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS01935 9f1226482abb9b3b326c43f420d11b97 506 SMART SM00244 120 302 4.5E-10 T 06-07-2017 IPR001107 Band 7 domain GTHT12_RS01935 9f1226482abb9b3b326c43f420d11b97 506 Pfam PF01145 SPFH domain / Band 7 family 30 221 4.2E-26 T 06-07-2017 IPR001107 Band 7 domain GTHT12_RS01935 9f1226482abb9b3b326c43f420d11b97 506 SUPERFAMILY SSF117892 69 211 3.79E-36 T 06-07-2017 IPR001107 Band 7 domain GTHT12_RS01935 9f1226482abb9b3b326c43f420d11b97 506 Pfam PF15975 Flotillin 369 463 3.2E-14 T 06-07-2017 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 GTHT12_RS15320 08e9f08034638e269d75db9da8e9a5a8 174 Gene3D G3DSA:2.60.40.200 28 172 5.2E-52 T 06-07-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS15320 08e9f08034638e269d75db9da8e9a5a8 174 ProSitePatterns PS00087 Copper/Zinc superoxide dismutase signature 1. 66 76 - T 06-07-2017 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS15320 08e9f08034638e269d75db9da8e9a5a8 174 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 36 171 1.4E-42 T 06-07-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS15320 08e9f08034638e269d75db9da8e9a5a8 174 SUPERFAMILY SSF49329 27 172 9.82E-46 T 06-07-2017 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS15635 68a8fd16d8eb7e7fb6d38e6c5d1aaefa 104 SUPERFAMILY SSF52833 7 99 2.49E-14 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS15635 68a8fd16d8eb7e7fb6d38e6c5d1aaefa 104 Gene3D G3DSA:3.40.30.10 7 98 4.5E-11 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS15635 68a8fd16d8eb7e7fb6d38e6c5d1aaefa 104 Pfam PF00085 Thioredoxin 5 84 4.7E-7 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 GTHT12_RS02660 0631097b97e8173c7afb2e06e0d85ee4 368 SUPERFAMILY SSF140453 1 92 5.1E-7 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like GTHT12_RS02660 0631097b97e8173c7afb2e06e0d85ee4 368 Pfam PF14449 Pre-toxin TG 86 155 1.1E-16 T 06-07-2017 IPR027797 Pre-toxin TG domain GTHT12_RS01205 7a126b0df52809d354e5db113215a60b 228 Gene3D G3DSA:3.40.50.2300 3 125 2.7E-41 T 06-07-2017 GTHT12_RS01205 7a126b0df52809d354e5db113215a60b 228 SMART SM00448 3 113 3.2E-44 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS01205 7a126b0df52809d354e5db113215a60b 228 Gene3D G3DSA:1.10.10.10 126 226 8.4E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS01205 7a126b0df52809d354e5db113215a60b 228 SUPERFAMILY SSF52172 2 130 9.39E-41 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS01205 7a126b0df52809d354e5db113215a60b 228 Pfam PF00072 Response regulator receiver domain 6 114 1.7E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS01205 7a126b0df52809d354e5db113215a60b 228 SUPERFAMILY SSF46894 123 224 2.58E-29 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GTHT12_RS01205 7a126b0df52809d354e5db113215a60b 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 2.4E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS01205 7a126b0df52809d354e5db113215a60b 228 SMART SM00862 148 224 3.9E-28 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS10230 16007a0a5e51b1016913682f6cd24af4 477 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 204 452 7.9E-51 T 06-07-2017 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 GTHT12_RS10230 16007a0a5e51b1016913682f6cd24af4 477 PRINTS PR00084 Mannitol dehydrogenase signature 205 218 4.8E-6 T 06-07-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 GTHT12_RS10230 16007a0a5e51b1016913682f6cd24af4 477 PRINTS PR00084 Mannitol dehydrogenase signature 164 177 4.8E-6 T 06-07-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 GTHT12_RS10230 16007a0a5e51b1016913682f6cd24af4 477 PRINTS PR00084 Mannitol dehydrogenase signature 19 29 4.8E-6 T 06-07-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 GTHT12_RS10230 16007a0a5e51b1016913682f6cd24af4 477 PRINTS PR00084 Mannitol dehydrogenase signature 235 250 4.8E-6 T 06-07-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 GTHT12_RS10230 16007a0a5e51b1016913682f6cd24af4 477 Gene3D G3DSA:3.40.50.720 12 268 1.5E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS10230 16007a0a5e51b1016913682f6cd24af4 477 Gene3D G3DSA:1.10.1040.10 272 476 2.6E-57 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 GTHT12_RS10230 16007a0a5e51b1016913682f6cd24af4 477 SUPERFAMILY SSF51735 12 267 6.69E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS10230 16007a0a5e51b1016913682f6cd24af4 477 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 18 172 6.0E-23 T 06-07-2017 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 GTHT12_RS10230 16007a0a5e51b1016913682f6cd24af4 477 SUPERFAMILY SSF48179 273 475 8.5E-45 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GTHT12_RS13955 4d29b73664e46c8922410b27151baa43 151 Pfam PF10702 Protein of unknown function (DUF2507) 21 143 4.8E-45 T 06-07-2017 IPR019642 Protein of unknown function DUF2507 GTHT12_RS13955 4d29b73664e46c8922410b27151baa43 151 SUPERFAMILY SSF111126 17 130 1.73E-22 T 06-07-2017 IPR024096 NO signalling/Golgi transport ligand-binding domain GTHT12_RS13955 4d29b73664e46c8922410b27151baa43 151 Gene3D G3DSA:3.30.1380.20 19 120 9.3E-15 T 06-07-2017 GTHT12_RS11685 63450e330c31a4e25b648d0f521784ce 320 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 GTHT12_RS11685 63450e330c31a4e25b648d0f521784ce 320 Gene3D G3DSA:1.10.600.10 3 319 4.9E-96 T 06-07-2017 IPR008949 Isoprenoid synthase domain GTHT12_RS11685 63450e330c31a4e25b648d0f521784ce 320 TIGRFAM TIGR02748 GerC3_HepT: heptaprenyl diphosphate synthase component II 2 320 7.7E-169 T 06-07-2017 IPR014119 Heptaprenyl diphosphate synthase component II KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 GTHT12_RS11685 63450e330c31a4e25b648d0f521784ce 320 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 GTHT12_RS11685 63450e330c31a4e25b648d0f521784ce 320 SUPERFAMILY SSF48576 5 320 1.73E-88 T 06-07-2017 IPR008949 Isoprenoid synthase domain GTHT12_RS11685 63450e330c31a4e25b648d0f521784ce 320 Pfam PF00348 Polyprenyl synthetase 33 256 4.5E-66 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 GTHT12_RS00260 fa5dcf41b953b2ec1dc8a125f6c21ec6 96 SUPERFAMILY SSF160537 1 87 1.96E-33 T 06-07-2017 IPR007170 Stage V sporulation protein G GO:0030435 GTHT12_RS00260 fa5dcf41b953b2ec1dc8a125f6c21ec6 96 Gene3D G3DSA:3.30.1120.40 1 82 2.0E-38 T 06-07-2017 IPR007170 Stage V sporulation protein G GO:0030435 GTHT12_RS00260 fa5dcf41b953b2ec1dc8a125f6c21ec6 96 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 92 28.465 T 06-07-2017 IPR007170 Stage V sporulation protein G GO:0030435 GTHT12_RS00260 fa5dcf41b953b2ec1dc8a125f6c21ec6 96 Pfam PF04026 SpoVG 1 81 1.4E-36 T 06-07-2017 IPR007170 Stage V sporulation protein G GO:0030435 GTHT12_RS04740 c1de0d2de0bb0038ed8c6f5365f6ebb0 397 SUPERFAMILY SSF103473 4 387 4.05E-60 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS04740 c1de0d2de0bb0038ed8c6f5365f6ebb0 397 Gene3D G3DSA:1.20.1250.20 208 385 2.7E-14 T 06-07-2017 GTHT12_RS04740 c1de0d2de0bb0038ed8c6f5365f6ebb0 397 Pfam PF07690 Major Facilitator Superfamily 16 321 1.4E-38 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS04740 c1de0d2de0bb0038ed8c6f5365f6ebb0 397 Gene3D G3DSA:1.20.1250.20 11 194 8.6E-27 T 06-07-2017 GTHT12_RS00810 435d927f6ecbd6ab96f52852b271ef27 291 SMART SM00382 32 223 7.7E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS00810 435d927f6ecbd6ab96f52852b271ef27 291 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 281 3.3E-122 T 06-07-2017 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 GTHT12_RS00810 435d927f6ecbd6ab96f52852b271ef27 291 Gene3D G3DSA:3.40.50.300 3 240 3.3E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00810 435d927f6ecbd6ab96f52852b271ef27 291 SUPERFAMILY SSF52540 5 239 5.89E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00810 435d927f6ecbd6ab96f52852b271ef27 291 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS00810 435d927f6ecbd6ab96f52852b271ef27 291 Pfam PF00005 ABC transporter 24 174 3.7E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS16365 17f8856515e609f696161cb944777cc0 388 Pfam PF00872 Transposase, Mutator family 13 365 3.6E-101 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS16365 17f8856515e609f696161cb944777cc0 388 ProSitePatterns PS01007 Transposases, Mutator family, signature. 220 244 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS05325 9ab920fb43c07ba8e3c86e548f861726 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 190 5.8E-4 T 06-07-2017 GTHT12_RS05325 9ab920fb43c07ba8e3c86e548f861726 249 SUPERFAMILY SSF51735 5 242 3.36E-84 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS05325 9ab920fb43c07ba8e3c86e548f861726 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.5E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05325 9ab920fb43c07ba8e3c86e548f861726 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.5E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05325 9ab920fb43c07ba8e3c86e548f861726 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.5E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05325 9ab920fb43c07ba8e3c86e548f861726 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 9.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05325 9ab920fb43c07ba8e3c86e548f861726 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 9.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05325 9ab920fb43c07ba8e3c86e548f861726 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 9.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05325 9ab920fb43c07ba8e3c86e548f861726 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 9.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05325 9ab920fb43c07ba8e3c86e548f861726 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 9.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05325 9ab920fb43c07ba8e3c86e548f861726 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 9.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05325 9ab920fb43c07ba8e3c86e548f861726 249 Gene3D G3DSA:3.40.50.720 5 245 7.8E-88 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS05325 9ab920fb43c07ba8e3c86e548f861726 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GTHT12_RS05325 9ab920fb43c07ba8e3c86e548f861726 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 242 2.2E-72 T 06-07-2017 GTHT12_RS06550 5489b81d253fa372d0c1c6b863695d8c 735 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 238 395 3.0E-40 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 GTHT12_RS06550 5489b81d253fa372d0c1c6b863695d8c 735 Gene3D G3DSA:3.40.50.300 225 396 4.7E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06550 5489b81d253fa372d0c1c6b863695d8c 735 SUPERFAMILY SSF50447 408 491 7.07E-28 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain GTHT12_RS06550 5489b81d253fa372d0c1c6b863695d8c 735 ProSitePatterns PS01176 Initiation factor 2 signature. 687 709 - T 06-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 GTHT12_RS06550 5489b81d253fa372d0c1c6b863695d8c 735 Gene3D G3DSA:3.40.50.10050 536 615 3.3E-27 T 06-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 GTHT12_RS06550 5489b81d253fa372d0c1c6b863695d8c 735 Gene3D G3DSA:2.40.30.10 637 734 4.4E-41 T 06-07-2017 GTHT12_RS06550 5489b81d253fa372d0c1c6b863695d8c 735 SUPERFAMILY SSF52156 517 643 1.16E-40 T 06-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 GTHT12_RS06550 5489b81d253fa372d0c1c6b863695d8c 735 SUPERFAMILY SSF52540 229 409 9.35E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06550 5489b81d253fa372d0c1c6b863695d8c 735 Pfam PF00009 Elongation factor Tu GTP binding domain 241 396 1.2E-35 T 06-07-2017 GTHT12_RS06550 5489b81d253fa372d0c1c6b863695d8c 735 SUPERFAMILY SSF50447 637 734 5.2E-36 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain GTHT12_RS06550 5489b81d253fa372d0c1c6b863695d8c 735 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 734 17.991 T 06-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 GTHT12_RS06550 5489b81d253fa372d0c1c6b863695d8c 735 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 162 210 7.5E-16 T 06-07-2017 IPR006847 Translation initiation factor IF-2, N-terminal GTHT12_RS06550 5489b81d253fa372d0c1c6b863695d8c 735 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 50 4.4E-15 T 06-07-2017 IPR006847 Translation initiation factor IF-2, N-terminal GTHT12_RS06550 5489b81d253fa372d0c1c6b863695d8c 735 Pfam PF11987 Translation-initiation factor 2 522 626 2.5E-38 T 06-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 GTHT12_RS06550 5489b81d253fa372d0c1c6b863695d8c 735 Gene3D G3DSA:2.40.30.10 407 500 6.7E-27 T 06-07-2017 GTHT12_RS06550 5489b81d253fa372d0c1c6b863695d8c 735 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 152 734 7.2E-285 T 06-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 GTHT12_RS15940 3390b16d4bb93f0966334794051e8cc0 317 Gene3D G3DSA:3.40.50.10680 79 314 9.6E-62 T 06-07-2017 GTHT12_RS15940 3390b16d4bb93f0966334794051e8cc0 317 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 9 314 5.9E-126 T 06-07-2017 IPR010119 Gluconeogenesis factor GTHT12_RS15940 3390b16d4bb93f0966334794051e8cc0 317 Pfam PF01933 Uncharacterised protein family UPF0052 9 291 3.3E-109 T 06-07-2017 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 GTHT12_RS15940 3390b16d4bb93f0966334794051e8cc0 317 Hamap MF_00973 Gluconeogenesis factor. 5 316 36.314 T 06-07-2017 IPR010119 Gluconeogenesis factor GTHT12_RS15940 3390b16d4bb93f0966334794051e8cc0 317 SUPERFAMILY SSF142338 7 311 1.44E-105 T 06-07-2017 GTHT12_RS12480 05d357f6a485ab52277ba65e26b1fd1f 277 SMART SM00448 21 135 4.9E-32 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS12480 05d357f6a485ab52277ba65e26b1fd1f 277 PIRSF PIRSF002937 18 277 1.1E-130 T 06-07-2017 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 GTHT12_RS12480 05d357f6a485ab52277ba65e26b1fd1f 277 SUPERFAMILY SSF52172 21 143 7.12E-32 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS12480 05d357f6a485ab52277ba65e26b1fd1f 277 Gene3D G3DSA:1.10.10.10 159 275 3.6E-59 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12480 05d357f6a485ab52277ba65e26b1fd1f 277 Pfam PF08769 Sporulation initiation factor Spo0A C terminal 167 270 5.2E-45 T 06-07-2017 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 GTHT12_RS12480 05d357f6a485ab52277ba65e26b1fd1f 277 Pfam PF00072 Response regulator receiver domain 23 135 1.2E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS12480 05d357f6a485ab52277ba65e26b1fd1f 277 TIGRFAM TIGR02875 spore_0_A: sporulation transcription factor Spo0A 21 277 1.6E-128 T 06-07-2017 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 GTHT12_RS12480 05d357f6a485ab52277ba65e26b1fd1f 277 SUPERFAMILY SSF46894 160 275 3.06E-48 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GTHT12_RS12480 05d357f6a485ab52277ba65e26b1fd1f 277 Gene3D G3DSA:3.40.50.2300 20 147 4.5E-34 T 06-07-2017 GTHT12_RS12480 05d357f6a485ab52277ba65e26b1fd1f 277 ProDom PD010908 TRANSCRIPTION SPORULATION TWO-COMPONENT DNA-BINDING PHOSPHORYLATION SENSORY REGULATION TRANSDUCTION METAL-BINDING CALCIUM 166 276 2.0E-58 T 06-07-2017 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 GTHT12_RS03045 bcce612ab7ff232fa405eec1e886c249 600 Gene3D G3DSA:3.40.50.300 352 581 1.6E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03045 bcce612ab7ff232fa405eec1e886c249 600 ProSitePatterns PS00211 ABC transporters family signature. 490 504 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS03045 bcce612ab7ff232fa405eec1e886c249 600 SUPERFAMILY SSF52540 341 584 8.59E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03045 bcce612ab7ff232fa405eec1e886c249 600 Pfam PF00664 ABC transporter transmembrane region 40 306 2.5E-23 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GTHT12_RS03045 bcce612ab7ff232fa405eec1e886c249 600 Gene3D G3DSA:1.20.1560.10 27 336 3.0E-49 T 06-07-2017 GTHT12_RS03045 bcce612ab7ff232fa405eec1e886c249 600 SMART SM00382 378 562 1.9E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS03045 bcce612ab7ff232fa405eec1e886c249 600 Pfam PF00005 ABC transporter 369 518 7.0E-36 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS03045 bcce612ab7ff232fa405eec1e886c249 600 SUPERFAMILY SSF90123 26 336 1.05E-48 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GTHT12_RS10415 bda784302cd49741a85ad06ff3c466f3 443 Pfam PF02447 GntP family permease 4 316 1.9E-13 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 GTHT12_RS05390 2885dafb62f60e6a9728782e16949ce4 950 Pfam PF00676 Dehydrogenase E1 component 228 536 2.0E-71 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 GTHT12_RS05390 2885dafb62f60e6a9728782e16949ce4 950 SUPERFAMILY SSF52518 157 535 7.36E-74 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS05390 2885dafb62f60e6a9728782e16949ce4 950 Gene3D G3DSA:3.40.50.970 155 537 3.9E-67 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS05390 2885dafb62f60e6a9728782e16949ce4 950 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 15 943 0.0 T 06-07-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 GTHT12_RS05390 2885dafb62f60e6a9728782e16949ce4 950 Pfam PF02779 Transketolase, pyrimidine binding domain 601 799 4.1E-57 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain GTHT12_RS05390 2885dafb62f60e6a9728782e16949ce4 950 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 803 946 3.6E-39 T 06-07-2017 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 GTHT12_RS05390 2885dafb62f60e6a9728782e16949ce4 950 Hamap MF_01169 2-oxoglutarate dehydrogenase E1 component [odhA]. 1 948 24.164 T 06-07-2017 IPR023784 2-oxoglutarate dehydrogenase E1 component, bacterial KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 GTHT12_RS05390 2885dafb62f60e6a9728782e16949ce4 950 Gene3D G3DSA:3.40.50.970 601 804 3.8E-15 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS05390 2885dafb62f60e6a9728782e16949ce4 950 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 13 49 4.9E-10 T 06-07-2017 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 GTHT12_RS05390 2885dafb62f60e6a9728782e16949ce4 950 SUPERFAMILY SSF52518 584 804 4.22E-44 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS05390 2885dafb62f60e6a9728782e16949ce4 950 PIRSF PIRSF000157 1 948 0.0 T 06-07-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 GTHT12_RS05390 2885dafb62f60e6a9728782e16949ce4 950 SMART SM00861 602 798 3.9E-48 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain GTHT12_RS11595 be99c04b21d720433b5a3252a5d84b72 169 SUPERFAMILY SSF50022 2 160 2.23E-30 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 GTHT12_RS11595 be99c04b21d720433b5a3252a5d84b72 169 Pfam PF00355 Rieske [2Fe-2S] domain 74 149 2.5E-13 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 GTHT12_RS11595 be99c04b21d720433b5a3252a5d84b72 169 Gene3D G3DSA:2.102.10.10 5 164 1.6E-36 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 GTHT12_RS04295 d6846e10518d7658227d5e77cf06ee53 328 SUPERFAMILY SSF52374 2 324 6.06E-103 T 06-07-2017 GTHT12_RS04295 d6846e10518d7658227d5e77cf06ee53 328 Pfam PF00579 tRNA synthetases class I (W and Y) 3 281 1.1E-87 T 06-07-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS04295 d6846e10518d7658227d5e77cf06ee53 328 Gene3D G3DSA:3.40.50.620 2 206 2.8E-92 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS04295 d6846e10518d7658227d5e77cf06ee53 328 Gene3D G3DSA:1.10.240.10 207 294 3.1E-17 T 06-07-2017 GTHT12_RS04295 d6846e10518d7658227d5e77cf06ee53 328 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 139 160 3.8E-29 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 GTHT12_RS04295 d6846e10518d7658227d5e77cf06ee53 328 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 192 202 3.8E-29 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 GTHT12_RS04295 d6846e10518d7658227d5e77cf06ee53 328 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 3.8E-29 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 GTHT12_RS04295 d6846e10518d7658227d5e77cf06ee53 328 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 64 83 3.8E-29 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 GTHT12_RS04295 d6846e10518d7658227d5e77cf06ee53 328 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 324 4.5E-122 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 GTHT12_RS04295 d6846e10518d7658227d5e77cf06ee53 328 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 19 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS04295 d6846e10518d7658227d5e77cf06ee53 328 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 325 43.183 T 06-07-2017 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 GTHT12_RS09485 322b923b7f381e35f93079690c305951 132 Gene3D G3DSA:3.40.30.10 9 99 4.3E-27 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS09485 322b923b7f381e35f93079690c305951 132 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 10 86 5.0E-8 T 06-07-2017 GTHT12_RS09485 322b923b7f381e35f93079690c305951 132 SUPERFAMILY SSF52833 9 103 4.47E-25 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS12985 12ded9a91350bead53b883fc9cb5d0bb 316 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3 286 1.6E-90 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 GTHT12_RS12985 12ded9a91350bead53b883fc9cb5d0bb 316 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 288 32.279 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 GTHT12_RS12985 12ded9a91350bead53b883fc9cb5d0bb 316 Pfam PF02401 LytB protein 4 284 3.4E-81 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 GTHT12_RS13680 a46bbf35d7ef0cc9bc9744fc879d6abb 193 SUPERFAMILY SSF52972 2 185 2.35E-63 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like GTHT12_RS13680 a46bbf35d7ef0cc9bc9744fc879d6abb 193 Gene3D G3DSA:3.90.950.10 2 188 8.4E-72 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like GTHT12_RS13680 a46bbf35d7ef0cc9bc9744fc879d6abb 193 PIRSF PIRSF006305 1 190 6.7E-58 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 GTHT12_RS13680 a46bbf35d7ef0cc9bc9744fc879d6abb 193 TIGRFAM TIGR00172 maf: septum formation protein Maf 1 184 1.8E-58 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 GTHT12_RS13680 a46bbf35d7ef0cc9bc9744fc879d6abb 193 Pfam PF02545 Maf-like protein 4 185 3.7E-60 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 GTHT12_RS13680 a46bbf35d7ef0cc9bc9744fc879d6abb 193 Hamap MF_00528 Septum formation protein Maf [maf]. 4 190 32.018 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 GTHT12_RS10310 95be45f6a0b5b2564dab9f30fc74ecde 464 Pfam PF02954 Bacterial regulatory protein, Fis family 418 457 1.3E-5 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GTHT12_RS10310 95be45f6a0b5b2564dab9f30fc74ecde 464 SMART SM00091 10 77 0.0011 T 06-07-2017 IPR000014 PAS domain GTHT12_RS10310 95be45f6a0b5b2564dab9f30fc74ecde 464 Pfam PF13426 PAS domain 21 117 6.0E-7 T 06-07-2017 IPR000014 PAS domain GTHT12_RS10310 95be45f6a0b5b2564dab9f30fc74ecde 464 SUPERFAMILY SSF55785 10 111 2.62E-10 T 06-07-2017 IPR000014 PAS domain GTHT12_RS10310 95be45f6a0b5b2564dab9f30fc74ecde 464 Gene3D G3DSA:1.10.10.60 407 460 5.8E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS10310 95be45f6a0b5b2564dab9f30fc74ecde 464 SUPERFAMILY SSF46689 408 460 3.94E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS10310 95be45f6a0b5b2564dab9f30fc74ecde 464 Pfam PF00158 Sigma-54 interaction domain 147 314 1.8E-67 T 06-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 GTHT12_RS10310 95be45f6a0b5b2564dab9f30fc74ecde 464 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 123 4.9E-6 T 06-07-2017 IPR000014 PAS domain GTHT12_RS10310 95be45f6a0b5b2564dab9f30fc74ecde 464 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 360 369 - T 06-07-2017 IPR025944 Sigma-54 interaction domain, conserved site GTHT12_RS10310 95be45f6a0b5b2564dab9f30fc74ecde 464 Gene3D G3DSA:3.30.450.20 11 133 3.4E-14 T 06-07-2017 GTHT12_RS10310 95be45f6a0b5b2564dab9f30fc74ecde 464 Gene3D G3DSA:3.40.50.300 145 320 4.5E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10310 95be45f6a0b5b2564dab9f30fc74ecde 464 Gene3D G3DSA:1.10.8.60 321 397 2.7E-24 T 06-07-2017 GTHT12_RS10310 95be45f6a0b5b2564dab9f30fc74ecde 464 SMART SM00382 167 311 2.3E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS10310 95be45f6a0b5b2564dab9f30fc74ecde 464 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 171 184 - T 06-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 GTHT12_RS10310 95be45f6a0b5b2564dab9f30fc74ecde 464 SUPERFAMILY SSF52540 146 389 8.52E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 Gene3D G3DSA:3.40.50.1000 527 669 4.0E-47 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 Gene3D G3DSA:3.40.50.1000 371 411 4.0E-47 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 400 406 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 PRINTS PR00941 Cadmium-transporting ATPase signature 202 218 1.1E-60 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 PRINTS PR00941 Cadmium-transporting ATPase signature 26 47 1.1E-60 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 PRINTS PR00941 Cadmium-transporting ATPase signature 48 71 1.1E-60 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 PRINTS PR00941 Cadmium-transporting ATPase signature 263 279 1.1E-60 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 PRINTS PR00941 Cadmium-transporting ATPase signature 282 296 1.1E-60 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 PRINTS PR00941 Cadmium-transporting ATPase signature 15 24 1.1E-60 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 PRINTS PR00941 Cadmium-transporting ATPase signature 128 140 1.1E-60 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 PRINTS PR00941 Cadmium-transporting ATPase signature 182 202 1.1E-60 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 PRINTS PR00941 Cadmium-transporting ATPase signature 111 128 1.1E-60 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 SUPERFAMILY SSF81653 200 297 1.7E-25 T 06-07-2017 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 Gene3D G3DSA:3.40.1110.10 412 526 4.7E-21 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 169 680 2.9E-94 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 Pfam PF00122 E1-E2 ATPase 168 389 2.0E-65 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 Gene3D G3DSA:2.70.150.10 147 298 1.5E-28 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 147 703 1.5E-187 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 SUPERFAMILY SSF81665 298 392 3.01E-21 T 06-07-2017 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 SUPERFAMILY SSF81665 147 201 3.01E-21 T 06-07-2017 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 SUPERFAMILY SSF81665 650 689 3.01E-21 T 06-07-2017 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 ProSitePatterns PS01229 Hypothetical cof family signature 2. 600 622 - T 06-07-2017 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 129 703 3.3E-119 T 06-07-2017 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 SUPERFAMILY SSF56784 496 701 1.81E-58 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 SUPERFAMILY SSF56784 397 416 1.81E-58 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 148 454 1.2E-100 T 06-07-2017 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 ProSitePatterns PS01047 Heavy-metal-associated domain. 17 46 - T 06-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 Pfam PF00403 Heavy-metal-associated domain 14 63 1.6E-11 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 547 557 1.2E-25 T 06-07-2017 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 624 636 1.2E-25 T 06-07-2017 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 247 261 1.2E-25 T 06-07-2017 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 600 619 1.2E-25 T 06-07-2017 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 524 535 1.2E-25 T 06-07-2017 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 398 412 1.2E-25 T 06-07-2017 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 Pfam PF00702 haloacid dehalogenase-like hydrolase 395 614 6.4E-46 T 06-07-2017 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 Gene3D G3DSA:3.30.70.100 8 64 3.0E-12 T 06-07-2017 GTHT12_RS04035 a596e8ce743ab76a4e8f367a2b6f3843 708 SUPERFAMILY SSF55008 8 65 1.96E-11 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 GTHT12_RS18235 39cb12ddf810723194e9e1123a3eaec4 254 PRINTS PR01900 YidC translocation/secretion protein signature 175 190 3.7E-8 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 GTHT12_RS18235 39cb12ddf810723194e9e1123a3eaec4 254 PRINTS PR01900 YidC translocation/secretion protein signature 43 59 3.7E-8 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 GTHT12_RS18235 39cb12ddf810723194e9e1123a3eaec4 254 PRINTS PR01900 YidC translocation/secretion protein signature 197 221 3.7E-8 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 GTHT12_RS18235 39cb12ddf810723194e9e1123a3eaec4 254 Pfam PF02096 60Kd inner membrane protein 59 241 3.2E-60 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 GTHT12_RS18235 39cb12ddf810723194e9e1123a3eaec4 254 PRINTS PR00701 60kDa inner membrane protein signature 208 231 4.6E-15 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 GTHT12_RS18235 39cb12ddf810723194e9e1123a3eaec4 254 PRINTS PR00701 60kDa inner membrane protein signature 124 147 4.6E-15 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 GTHT12_RS18235 39cb12ddf810723194e9e1123a3eaec4 254 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 2 245 32.93 T 06-07-2017 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes GTHT12_RS18235 39cb12ddf810723194e9e1123a3eaec4 254 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 58 241 6.4E-67 T 06-07-2017 IPR028055 Membrane insertase YidC/Oxa1, C-terminal GTHT12_RS10120 cec6bbe1318cdc568d855587f371b1f1 541 Gene3D G3DSA:3.90.76.10 49 223 3.8E-52 T 06-07-2017 GTHT12_RS10120 cec6bbe1318cdc568d855587f371b1f1 541 PIRSF PIRSF002741 1 537 1.3E-119 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 GTHT12_RS10120 cec6bbe1318cdc568d855587f371b1f1 541 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 88 110 - T 06-07-2017 IPR023765 Solute-binding protein family 5, conserved site GTHT12_RS10120 cec6bbe1318cdc568d855587f371b1f1 541 Gene3D G3DSA:3.10.105.10 295 510 4.7E-61 T 06-07-2017 GTHT12_RS10120 cec6bbe1318cdc568d855587f371b1f1 541 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 462 9.2E-89 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain GTHT12_RS10120 cec6bbe1318cdc568d855587f371b1f1 541 SUPERFAMILY SSF53850 40 532 9.18E-136 T 06-07-2017 GTHT12_RS01835 0b9b1e203e45daa8ee01611a8163d3c5 445 SMART SM00382 149 293 1.1E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS01835 0b9b1e203e45daa8ee01611a8163d3c5 445 SUPERFAMILY SSF46689 343 444 1.11E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS01835 0b9b1e203e45daa8ee01611a8163d3c5 445 Gene3D G3DSA:1.10.8.60 304 355 7.9E-21 T 06-07-2017 GTHT12_RS01835 0b9b1e203e45daa8ee01611a8163d3c5 445 SUPERFAMILY SSF52540 128 369 2.15E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01835 0b9b1e203e45daa8ee01611a8163d3c5 445 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 425 445 2.5E-6 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GTHT12_RS01835 0b9b1e203e45daa8ee01611a8163d3c5 445 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 408 425 2.5E-6 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GTHT12_RS01835 0b9b1e203e45daa8ee01611a8163d3c5 445 Pfam PF02954 Bacterial regulatory protein, Fis family 403 442 1.3E-9 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GTHT12_RS01835 0b9b1e203e45daa8ee01611a8163d3c5 445 Gene3D G3DSA:3.40.50.300 125 302 1.3E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01835 0b9b1e203e45daa8ee01611a8163d3c5 445 Pfam PF00158 Sigma-54 interaction domain 129 296 4.0E-67 T 06-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 GTHT12_RS01835 0b9b1e203e45daa8ee01611a8163d3c5 445 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 153 166 - T 06-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 GTHT12_RS01835 0b9b1e203e45daa8ee01611a8163d3c5 445 Gene3D G3DSA:1.10.10.60 356 445 4.1E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS14195 1881e7c23e42192f54fc92194ea6b100 201 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 199 30.569 T 06-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 GTHT12_RS14195 1881e7c23e42192f54fc92194ea6b100 201 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 5 190 1.7E-66 T 06-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 GTHT12_RS14195 1881e7c23e42192f54fc92194ea6b100 201 Gene3D G3DSA:3.40.50.300 2 197 3.4E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS14195 1881e7c23e42192f54fc92194ea6b100 201 SUPERFAMILY SSF52540 1 195 9.94E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS14195 1881e7c23e42192f54fc92194ea6b100 201 Pfam PF01121 Dephospho-CoA kinase 4 183 5.5E-66 T 06-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 GTHT12_RS04575 f6ade92f576cb6c84175405f3a08e1ad 367 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 188 202 - T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 GTHT12_RS04575 f6ade92f576cb6c84175405f3a08e1ad 367 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 362 4.8E-133 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 GTHT12_RS04575 f6ade92f576cb6c84175405f3a08e1ad 367 PIRSF PIRSF001434 1 365 1.4E-124 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 GTHT12_RS04575 f6ade92f576cb6c84175405f3a08e1ad 367 Gene3D G3DSA:3.40.640.10 3 244 1.2E-93 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS04575 f6ade92f576cb6c84175405f3a08e1ad 367 Gene3D G3DSA:3.90.1150.10 245 363 1.2E-34 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS04575 f6ade92f576cb6c84175405f3a08e1ad 367 SUPERFAMILY SSF53383 17 363 9.41E-108 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS16030 7595e139f8cf11abc78ba3445ac7d809 309 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 3 306 42.507 T 06-07-2017 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 GTHT12_RS16030 7595e139f8cf11abc78ba3445ac7d809 309 SUPERFAMILY SSF75138 1 131 2.75E-39 T 06-07-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like GTHT12_RS16030 7595e139f8cf11abc78ba3445ac7d809 309 Pfam PF02603 HPr Serine kinase N terminus 4 127 1.8E-38 T 06-07-2017 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 GTHT12_RS16030 7595e139f8cf11abc78ba3445ac7d809 309 Gene3D G3DSA:3.40.50.300 133 305 4.1E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16030 7595e139f8cf11abc78ba3445ac7d809 309 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 6 302 3.0E-117 T 06-07-2017 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 GTHT12_RS16030 7595e139f8cf11abc78ba3445ac7d809 309 Gene3D G3DSA:3.40.1390.20 1 132 7.6E-48 T 06-07-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like GTHT12_RS16030 7595e139f8cf11abc78ba3445ac7d809 309 SUPERFAMILY SSF53795 132 298 2.93E-43 T 06-07-2017 GTHT12_RS16030 7595e139f8cf11abc78ba3445ac7d809 309 Pfam PF07475 HPr Serine kinase C-terminal domain 130 298 5.3E-78 T 06-07-2017 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 GTHT12_RS02040 76b784ef87b2ad8e0c54a71c1455ff3f 196 SUPERFAMILY SSF81301 32 190 5.56E-49 T 06-07-2017 GTHT12_RS02040 76b784ef87b2ad8e0c54a71c1455ff3f 196 Gene3D G3DSA:3.30.460.10 29 191 7.5E-59 T 06-07-2017 GTHT12_RS02040 76b784ef87b2ad8e0c54a71c1455ff3f 196 Pfam PF04229 GrpB protein 30 189 3.2E-56 T 06-07-2017 IPR007344 GrpB/Dephospho-CoA kinase GTHT12_RS15450 4631985bbd4c33ad1acffb082d4aaf41 78 SUPERFAMILY SSF117916 2 77 1.96E-27 T 06-07-2017 GTHT12_RS15450 4631985bbd4c33ad1acffb082d4aaf41 78 Pfam PF01106 NifU-like domain 10 75 7.9E-28 T 06-07-2017 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 GTHT12_RS15450 4631985bbd4c33ad1acffb082d4aaf41 78 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 14 65 5.0E-23 T 06-07-2017 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 GTHT12_RS15775 17bd95edea294b340179fc6cd10dd2c8 293 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 277 1.1E-38 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 258 792 3.1E-129 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 SUPERFAMILY SSF81665 738 758 2.09E-10 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 SUPERFAMILY SSF81665 260 296 2.09E-10 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 SUPERFAMILY SSF81665 393 488 2.09E-10 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 SUPERFAMILY SSF55008 72 141 6.81E-21 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 265 768 2.0E-97 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 Gene3D G3DSA:3.40.1110.10 509 616 2.1E-24 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 SUPERFAMILY SSF81653 296 392 1.15E-29 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 PRINTS PR00942 Copper-transporting ATPase 1 signature 6 31 3.4E-9 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 PRINTS PR00942 Copper-transporting ATPase 1 signature 208 233 3.4E-9 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 494 508 1.4E-28 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 689 708 1.4E-28 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 712 724 1.4E-28 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 614 625 1.4E-28 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 342 356 1.4E-28 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 636 646 1.4E-28 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 Gene3D G3DSA:3.40.50.1000 617 757 5.2E-61 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 Gene3D G3DSA:3.40.50.1000 465 508 5.2E-61 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 225 791 8.0E-204 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 Pfam PF00122 E1-E2 ATPase 263 485 3.9E-68 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 ProSitePatterns PS01047 Heavy-metal-associated domain. 78 107 - T 06-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 ProSitePatterns PS01047 Heavy-metal-associated domain. 11 39 - T 06-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 SUPERFAMILY SSF56784 493 512 1.43E-64 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 SUPERFAMILY SSF56784 547 789 1.43E-64 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 Gene3D G3DSA:2.70.150.10 224 393 2.7E-38 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 496 502 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 7 69 4.7E-11 T 06-07-2017 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 73 136 2.3E-11 T 06-07-2017 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 207 792 9.0E-194 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 Pfam PF00702 haloacid dehalogenase-like hydrolase 490 703 6.0E-48 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 PRINTS PR00943 Copper-transporting ATPase signature 117 137 1.3E-17 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 PRINTS PR00943 Copper-transporting ATPase signature 666 683 1.3E-17 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 PRINTS PR00943 Copper-transporting ATPase signature 477 492 1.3E-17 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 PRINTS PR00943 Copper-transporting ATPase signature 210 229 1.3E-17 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 PRINTS PR00943 Copper-transporting ATPase signature 415 429 1.3E-17 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 PRINTS PR00943 Copper-transporting ATPase signature 262 281 1.3E-17 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 Gene3D G3DSA:3.30.70.100 3 69 5.1E-24 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 SUPERFAMILY SSF55008 3 69 1.83E-19 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 Gene3D G3DSA:3.30.70.100 72 155 2.2E-24 T 06-07-2017 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 Pfam PF00403 Heavy-metal-associated domain 8 67 1.5E-15 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 GTHT12_RS08690 77c7274e92f76d888c627e4f99bd9e4a 798 Pfam PF00403 Heavy-metal-associated domain 75 136 3.7E-18 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 GTHT12_RS13010 31f0f841ea533b3175788ab2256a4088 375 Gene3D G3DSA:1.10.10.10 215 266 1.4E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS13010 31f0f841ea533b3175788ab2256a4088 375 SUPERFAMILY SSF88659 215 288 2.4E-24 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13010 31f0f841ea533b3175788ab2256a4088 375 Pfam PF03979 Sigma-70 factor, region 1.1 20 85 7.0E-16 T 06-07-2017 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 GTHT12_RS13010 31f0f841ea533b3175788ab2256a4088 375 Gene3D G3DSA:1.10.10.10 304 375 4.5E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS13010 31f0f841ea533b3175788ab2256a4088 375 Gene3D G3DSA:1.10.601.10 10 211 1.7E-75 T 06-07-2017 GTHT12_RS13010 31f0f841ea533b3175788ab2256a4088 375 Pfam PF04539 Sigma-70 region 3 221 297 2.0E-33 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13010 31f0f841ea533b3175788ab2256a4088 375 SUPERFAMILY SSF88946 103 212 1.31E-55 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13010 31f0f841ea533b3175788ab2256a4088 375 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 2 375 34.839 T 06-07-2017 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 GTHT12_RS13010 31f0f841ea533b3175788ab2256a4088 375 Pfam PF04542 Sigma-70 region 2 143 211 5.9E-22 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13010 31f0f841ea533b3175788ab2256a4088 375 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 335 361 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13010 31f0f841ea533b3175788ab2256a4088 375 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 166 179 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13010 31f0f841ea533b3175788ab2256a4088 375 SUPERFAMILY SSF88659 272 373 5.79E-30 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13010 31f0f841ea533b3175788ab2256a4088 375 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 138 374 9.2E-126 T 06-07-2017 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13010 31f0f841ea533b3175788ab2256a4088 375 Pfam PF04545 Sigma-70, region 4 310 363 3.6E-20 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13010 31f0f841ea533b3175788ab2256a4088 375 PRINTS PR00046 Major sigma-70 factor signature 314 326 3.2E-32 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13010 31f0f841ea533b3175788ab2256a4088 375 PRINTS PR00046 Major sigma-70 factor signature 190 198 3.2E-32 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13010 31f0f841ea533b3175788ab2256a4088 375 PRINTS PR00046 Major sigma-70 factor signature 335 350 3.2E-32 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13010 31f0f841ea533b3175788ab2256a4088 375 PRINTS PR00046 Major sigma-70 factor signature 166 179 3.2E-32 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13010 31f0f841ea533b3175788ab2256a4088 375 PRINTS PR00046 Major sigma-70 factor signature 350 361 3.2E-32 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13010 31f0f841ea533b3175788ab2256a4088 375 Pfam PF00140 Sigma-70 factor, region 1.2 104 137 2.2E-20 T 06-07-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS13010 31f0f841ea533b3175788ab2256a4088 375 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 138 363 3.5E-39 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS10730 4487b01f87a07e6c346d0a181836803c 316 Pfam PF03060 Nitronate monooxygenase 7 302 1.7E-63 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 GTHT12_RS10730 4487b01f87a07e6c346d0a181836803c 316 Gene3D G3DSA:3.20.20.70 3 297 7.6E-72 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS10730 4487b01f87a07e6c346d0a181836803c 316 SUPERFAMILY SSF51412 4 308 4.27E-70 T 06-07-2017 GTHT12_RS07070 764a86283aa9337d467b9bdf086dbc73 491 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 434 476 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 GTHT12_RS07070 764a86283aa9337d467b9bdf086dbc73 491 Pfam PF00072 Response regulator receiver domain 4 114 3.4E-6 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS07070 764a86283aa9337d467b9bdf086dbc73 491 Gene3D G3DSA:3.40.50.2300 1 119 2.8E-11 T 06-07-2017 GTHT12_RS07070 764a86283aa9337d467b9bdf086dbc73 491 Gene3D G3DSA:1.10.10.60 377 434 1.3E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS07070 764a86283aa9337d467b9bdf086dbc73 491 SUPERFAMILY SSF46689 433 484 2.97E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS07070 764a86283aa9337d467b9bdf086dbc73 491 SUPERFAMILY SSF52172 2 119 1.71E-11 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS07070 764a86283aa9337d467b9bdf086dbc73 491 Pfam PF12833 Helix-turn-helix domain 404 481 2.3E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 GTHT12_RS07070 764a86283aa9337d467b9bdf086dbc73 491 Gene3D G3DSA:1.10.10.60 435 484 5.6E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS07070 764a86283aa9337d467b9bdf086dbc73 491 SMART SM00342 397 480 1.3E-26 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 GTHT12_RS02245 ecd131f61007a746915fb34439793c78 507 Gene3D G3DSA:3.30.450.20 140 254 9.4E-17 T 06-07-2017 GTHT12_RS02245 ecd131f61007a746915fb34439793c78 507 SUPERFAMILY SSF55785 46 150 9.71E-12 T 06-07-2017 IPR000014 PAS domain GTHT12_RS02245 ecd131f61007a746915fb34439793c78 507 SMART SM00086 100 142 0.0025 T 06-07-2017 IPR001610 PAC motif GTHT12_RS02245 ecd131f61007a746915fb34439793c78 507 SMART SM00086 221 263 29.0 T 06-07-2017 IPR001610 PAC motif GTHT12_RS02245 ecd131f61007a746915fb34439793c78 507 Gene3D G3DSA:3.30.450.20 19 139 1.6E-14 T 06-07-2017 GTHT12_RS02245 ecd131f61007a746915fb34439793c78 507 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 155 255 3.8E-10 T 06-07-2017 IPR000014 PAS domain GTHT12_RS02245 ecd131f61007a746915fb34439793c78 507 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 45 147 6.2E-7 T 06-07-2017 IPR000014 PAS domain GTHT12_RS02245 ecd131f61007a746915fb34439793c78 507 SUPERFAMILY SSF55785 138 254 1.16E-16 T 06-07-2017 IPR000014 PAS domain GTHT12_RS02245 ecd131f61007a746915fb34439793c78 507 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 317 506 8.6E-35 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 GTHT12_RS02245 ecd131f61007a746915fb34439793c78 507 SUPERFAMILY SSF81606 304 506 1.52E-8 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 GTHT12_RS02245 ecd131f61007a746915fb34439793c78 507 Pfam PF13426 PAS domain 162 256 3.3E-8 T 06-07-2017 IPR000014 PAS domain GTHT12_RS02245 ecd131f61007a746915fb34439793c78 507 SMART SM00091 25 96 7.9 T 06-07-2017 IPR000014 PAS domain GTHT12_RS02245 ecd131f61007a746915fb34439793c78 507 SMART SM00091 150 215 0.0048 T 06-07-2017 IPR000014 PAS domain GTHT12_RS02245 ecd131f61007a746915fb34439793c78 507 SMART SM00331 290 506 6.8E-34 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 GTHT12_RS02245 ecd131f61007a746915fb34439793c78 507 Pfam PF08447 PAS fold 49 125 3.4E-9 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 GTHT12_RS13990 1e7f099292f0d0705c5a65437e8894fa 261 Gene3D G3DSA:1.10.3720.10 56 252 5.0E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS13990 1e7f099292f0d0705c5a65437e8894fa 261 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 251 6.0E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS13990 1e7f099292f0d0705c5a65437e8894fa 261 SUPERFAMILY SSF161098 58 239 3.14E-36 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS05970 53c839dadd2635111ec44880eb6c3db4 924 SUPERFAMILY SSF52374 1 200 1.39E-157 T 06-07-2017 GTHT12_RS05970 53c839dadd2635111ec44880eb6c3db4 924 SUPERFAMILY SSF52374 392 639 1.39E-157 T 06-07-2017 GTHT12_RS05970 53c839dadd2635111ec44880eb6c3db4 924 SUPERFAMILY SSF47323 643 920 2.06E-80 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS05970 53c839dadd2635111ec44880eb6c3db4 924 Pfam PF06827 Zinc finger found in FPG and IleRS 888 917 3.1E-9 T 06-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 GTHT12_RS05970 53c839dadd2635111ec44880eb6c3db4 924 Gene3D G3DSA:3.90.740.10 204 378 1.3E-65 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 GTHT12_RS05970 53c839dadd2635111ec44880eb6c3db4 924 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS05970 53c839dadd2635111ec44880eb6c3db4 924 Gene3D G3DSA:3.40.50.620 392 630 1.0E-150 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS05970 53c839dadd2635111ec44880eb6c3db4 924 Gene3D G3DSA:3.40.50.620 16 203 1.0E-150 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS05970 53c839dadd2635111ec44880eb6c3db4 924 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 632 3.0E-230 T 06-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS05970 53c839dadd2635111ec44880eb6c3db4 924 SUPERFAMILY SSF50677 201 392 1.47E-66 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 GTHT12_RS05970 53c839dadd2635111ec44880eb6c3db4 924 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 7.6E-33 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 GTHT12_RS05970 53c839dadd2635111ec44880eb6c3db4 924 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 390 405 7.6E-33 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 GTHT12_RS05970 53c839dadd2635111ec44880eb6c3db4 924 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 552 561 7.6E-33 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 GTHT12_RS05970 53c839dadd2635111ec44880eb6c3db4 924 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 518 531 7.6E-33 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 GTHT12_RS05970 53c839dadd2635111ec44880eb6c3db4 924 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 228 251 7.6E-33 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 GTHT12_RS05970 53c839dadd2635111ec44880eb6c3db4 924 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 919 21.423 T 06-07-2017 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 GTHT12_RS05970 53c839dadd2635111ec44880eb6c3db4 924 Gene3D G3DSA:1.10.730.10 632 818 6.3E-49 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS05970 53c839dadd2635111ec44880eb6c3db4 924 Pfam PF08264 Anticodon-binding domain of tRNA 676 832 9.1E-34 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 GTHT12_RS05970 53c839dadd2635111ec44880eb6c3db4 924 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 13 833 0.0 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 GTHT12_RS18740 bd6caa87c2ae0740a8943134864175bd 387 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 255 265 - T 06-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site GTHT12_RS18740 bd6caa87c2ae0740a8943134864175bd 387 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 93 103 - T 06-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site GTHT12_RS18740 bd6caa87c2ae0740a8943134864175bd 387 Gene3D G3DSA:3.40.50.200 26 306 6.1E-87 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 GTHT12_RS18740 bd6caa87c2ae0740a8943134864175bd 387 Pfam PF00082 Subtilase family 47 295 5.1E-51 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 GTHT12_RS18740 bd6caa87c2ae0740a8943134864175bd 387 SUPERFAMILY SSF52743 34 294 5.5E-82 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 GTHT12_RS18740 bd6caa87c2ae0740a8943134864175bd 387 PRINTS PR00723 Subtilisin serine protease family (S8) signature 89 102 6.3E-23 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related GTHT12_RS18740 bd6caa87c2ae0740a8943134864175bd 387 PRINTS PR00723 Subtilisin serine protease family (S8) signature 47 66 6.3E-23 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related GTHT12_RS18740 bd6caa87c2ae0740a8943134864175bd 387 PRINTS PR00723 Subtilisin serine protease family (S8) signature 254 270 6.3E-23 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related GTHT12_RS18740 bd6caa87c2ae0740a8943134864175bd 387 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 52 63 - T 06-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site GTHT12_RS00325 ed4ac13f3c685183fbd47c8d768b77c5 101 ProDom PD067726 YABP B.SUBTILIS PRECURSOR UNCHARACTERIZED BH0074 SIGNAL CPE2477 PROTEIN 18 101 8.0E-42 T 06-07-2017 IPR012504 Sporulation protein YabP GTHT12_RS00325 ed4ac13f3c685183fbd47c8d768b77c5 101 PIRSF PIRSF011576 1 101 4.5E-50 T 06-07-2017 IPR012504 Sporulation protein YabP GTHT12_RS00325 ed4ac13f3c685183fbd47c8d768b77c5 101 TIGRFAM TIGR02892 spore_yabP: sporulation protein YabP 19 101 2.6E-33 T 06-07-2017 IPR012504 Sporulation protein YabP GTHT12_RS00325 ed4ac13f3c685183fbd47c8d768b77c5 101 Pfam PF07873 YabP family 19 84 5.4E-20 T 06-07-2017 IPR022476 Sporulation protein YabP/YqfC GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 Gene3D G3DSA:2.40.30.10 394 464 7.7E-41 T 06-07-2017 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 Gene3D G3DSA:2.40.30.10 235 285 7.7E-41 T 06-07-2017 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 SUPERFAMILY SSF63380 235 455 3.12E-66 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 SUPERFAMILY SSF52218 64 209 1.92E-51 T 06-07-2017 IPR029039 Flavoprotein-like domain GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 TIGRFAM TIGR01931 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component 6 609 6.0E-263 T 06-07-2017 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 Gene3D G3DSA:3.40.50.360 63 210 1.4E-52 T 06-07-2017 IPR029039 Flavoprotein-like domain GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 Pfam PF00667 FAD binding domain 237 434 1.6E-35 T 06-07-2017 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 Gene3D G3DSA:3.40.50.80 465 608 1.4E-61 T 06-07-2017 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 Pfam PF00258 Flavodoxin 68 199 2.3E-36 T 06-07-2017 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 PRINTS PR00369 Flavodoxin signature 171 190 7.6E-16 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 PRINTS PR00369 Flavodoxin signature 67 80 7.6E-16 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 PRINTS PR00369 Flavodoxin signature 147 157 7.6E-16 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 PRINTS PR00369 Flavodoxin signature 115 126 7.6E-16 T 06-07-2017 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 PIRSF PIRSF000207 1 609 1.1E-265 T 06-07-2017 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 Gene3D G3DSA:1.20.990.10 286 393 5.8E-30 T 06-07-2017 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 GO:0016491|GO:0055114 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 SUPERFAMILY SSF52343 454 609 5.5E-53 T 06-07-2017 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 466 485 1.1E-28 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 429 438 1.1E-28 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 491 500 1.1E-28 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 558 566 1.1E-28 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 504 515 1.1E-28 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 535 551 1.1E-28 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 275 285 1.1E-28 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 396 403 1.1E-28 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 GTHT12_RS07320 3052c8ef30eacc0b5d7b0a2876e36a93 609 Pfam PF00175 Oxidoreductase NAD-binding domain 467 573 3.8E-18 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 GTHT12_RS11540 e63725c791636341147e6da8fc947595 404 SUPERFAMILY SSF81301 5 139 9.05E-44 T 06-07-2017 GTHT12_RS11540 e63725c791636341147e6da8fc947595 404 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 169 228 1.0E-16 T 06-07-2017 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 GTHT12_RS11540 e63725c791636341147e6da8fc947595 404 Gene3D G3DSA:3.30.460.10 6 142 6.1E-50 T 06-07-2017 GTHT12_RS11540 e63725c791636341147e6da8fc947595 404 Pfam PF01743 Poly A polymerase head domain 22 142 2.4E-36 T 06-07-2017 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 GTHT12_RS11540 e63725c791636341147e6da8fc947595 404 Gene3D G3DSA:1.10.3090.10 143 364 1.2E-46 T 06-07-2017 GTHT12_RS11540 e63725c791636341147e6da8fc947595 404 Hamap MF_01263 CCA-adding enzyme [cca]. 2 397 41.575 T 06-07-2017 IPR023068 CCA-adding enzyme, firmicutes GO:0001680|GO:0004810|GO:0016437 GTHT12_RS11540 e63725c791636341147e6da8fc947595 404 SUPERFAMILY SSF81891 140 397 3.14E-59 T 06-07-2017 GTHT12_RS11540 e63725c791636341147e6da8fc947595 404 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 248 392 1.9E-30 T 06-07-2017 IPR032810 CCA-adding enzyme, C-terminal GTHT12_RS01200 012857eab0c6953ee9cde873dbfd1c64 443 Gene3D G3DSA:1.10.287.130 213 282 1.1E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS01200 012857eab0c6953ee9cde873dbfd1c64 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 398 2.9E-20 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS01200 012857eab0c6953ee9cde873dbfd1c64 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 442 2.9E-20 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS01200 012857eab0c6953ee9cde873dbfd1c64 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 423 2.9E-20 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS01200 012857eab0c6953ee9cde873dbfd1c64 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 384 2.9E-20 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS01200 012857eab0c6953ee9cde873dbfd1c64 443 SMART SM00388 223 287 9.6E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS01200 012857eab0c6953ee9cde873dbfd1c64 443 SUPERFAMILY SSF158472 171 219 1.01E-6 T 06-07-2017 GTHT12_RS01200 012857eab0c6953ee9cde873dbfd1c64 443 Pfam PF00672 HAMP domain 151 219 1.9E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS01200 012857eab0c6953ee9cde873dbfd1c64 443 SUPERFAMILY SSF55874 276 443 6.55E-52 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS01200 012857eab0c6953ee9cde873dbfd1c64 443 SUPERFAMILY SSF47384 206 288 9.42E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS01200 012857eab0c6953ee9cde873dbfd1c64 443 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 334 442 7.5E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS01200 012857eab0c6953ee9cde873dbfd1c64 443 Pfam PF00512 His Kinase A (phospho-acceptor) domain 224 287 1.9E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS01200 012857eab0c6953ee9cde873dbfd1c64 443 Gene3D G3DSA:3.30.565.10 293 442 3.4E-51 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS01200 012857eab0c6953ee9cde873dbfd1c64 443 SMART SM00387 333 443 1.6E-39 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS01200 012857eab0c6953ee9cde873dbfd1c64 443 SMART SM00304 170 222 2.4E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS15650 8b38f7c0c358abf3664267a546f894aa 127 SUPERFAMILY SSF51230 3 126 2.17E-47 T 06-07-2017 IPR011053 Single hybrid motif GTHT12_RS15650 8b38f7c0c358abf3664267a546f894aa 127 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 2 126 1.1E-57 T 06-07-2017 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 GTHT12_RS15650 8b38f7c0c358abf3664267a546f894aa 127 Pfam PF01597 Glycine cleavage H-protein 7 126 3.3E-51 T 06-07-2017 IPR002930 Glycine cleavage system H-protein GTHT12_RS15650 8b38f7c0c358abf3664267a546f894aa 127 Gene3D G3DSA:2.40.50.100 6 126 5.2E-53 T 06-07-2017 GTHT12_RS15650 8b38f7c0c358abf3664267a546f894aa 127 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 GTHT12_RS15650 8b38f7c0c358abf3664267a546f894aa 127 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 30.357 T 06-07-2017 IPR002930 Glycine cleavage system H-protein GTHT12_RS11905 43a1403bbee4a932f250696fa173972b 524 Gene3D G3DSA:3.40.50.720 3 104 1.7E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS11905 43a1403bbee4a932f250696fa173972b 524 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 189 211 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site GTHT12_RS11905 43a1403bbee4a932f250696fa173972b 524 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 141 168 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 GTHT12_RS11905 43a1403bbee4a932f250696fa173972b 524 SUPERFAMILY SSF51735 95 279 2.61E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS11905 43a1403bbee4a932f250696fa173972b 524 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 104 278 6.0E-65 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 GTHT12_RS11905 43a1403bbee4a932f250696fa173972b 524 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 310 9.7E-37 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 GTHT12_RS11905 43a1403bbee4a932f250696fa173972b 524 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 218 234 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site GTHT12_RS11905 43a1403bbee4a932f250696fa173972b 524 SUPERFAMILY SSF52283 32 126 9.64E-36 T 06-07-2017 GTHT12_RS11905 43a1403bbee4a932f250696fa173972b 524 Gene3D G3DSA:3.40.50.720 105 280 2.4E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS11905 43a1403bbee4a932f250696fa173972b 524 SUPERFAMILY SSF143548 316 446 8.37E-32 T 06-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 GTHT12_RS11905 43a1403bbee4a932f250696fa173972b 524 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 3 522 1.8E-214 T 06-07-2017 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 GTHT12_RS11905 43a1403bbee4a932f250696fa173972b 524 Gene3D G3DSA:3.30.70.260 446 520 5.3E-22 T 06-07-2017 GTHT12_RS11905 43a1403bbee4a932f250696fa173972b 524 Pfam PF01842 ACT domain 452 513 2.1E-11 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 GTHT12_RS11905 43a1403bbee4a932f250696fa173972b 524 SUPERFAMILY SSF55021 448 522 2.75E-20 T 06-07-2017 GTHT12_RS11905 43a1403bbee4a932f250696fa173972b 524 Gene3D G3DSA:3.30.1330.90 315 445 2.7E-38 T 06-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 GTHT12_RS12395 51ec705cd94d210ed35672b3c22933b4 731 Pfam PF02310 B12 binding domain 597 709 5.5E-17 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 GTHT12_RS12395 51ec705cd94d210ed35672b3c22933b4 731 SUPERFAMILY SSF51703 18 557 6.54E-224 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 GTHT12_RS12395 51ec705cd94d210ed35672b3c22933b4 731 SUPERFAMILY SSF52242 561 724 1.7E-61 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 GTHT12_RS12395 51ec705cd94d210ed35672b3c22933b4 731 Pfam PF01642 Methylmalonyl-CoA mutase 42 553 1.2E-240 T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 GTHT12_RS12395 51ec705cd94d210ed35672b3c22933b4 731 Gene3D G3DSA:3.40.50.280 561 721 1.8E-74 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 GTHT12_RS12395 51ec705cd94d210ed35672b3c22933b4 731 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 384 409 - T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 GTHT12_RS12395 51ec705cd94d210ed35672b3c22933b4 731 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 594 722 6.2E-64 T 06-07-2017 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 GTHT12_RS12395 51ec705cd94d210ed35672b3c22933b4 731 Gene3D G3DSA:3.20.20.240 41 510 3.3E-211 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 GTHT12_RS12395 51ec705cd94d210ed35672b3c22933b4 731 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 41 562 8.7E-274 T 06-07-2017 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 GTHT12_RS09115 a21578cb417453102c9c86d68d0ea78d 148 Pfam PF02082 Transcriptional regulator 1 82 4.6E-24 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type GTHT12_RS09115 a21578cb417453102c9c86d68d0ea78d 148 SUPERFAMILY SSF46785 2 135 4.93E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS09115 a21578cb417453102c9c86d68d0ea78d 148 Gene3D G3DSA:1.10.10.10 1 140 3.3E-44 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS09115 a21578cb417453102c9c86d68d0ea78d 148 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 06-07-2017 IPR030489 Transcription regulator Rrf2-type, conserved site GTHT12_RS09115 a21578cb417453102c9c86d68d0ea78d 148 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 132 4.8E-36 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type GTHT12_RS05570 54783bee4e193e263b44a84db3d419ca 184 PRINTS PR01576 Peptide deformylase signature 47 76 6.8E-31 T 06-07-2017 IPR023635 Peptide deformylase GTHT12_RS05570 54783bee4e193e263b44a84db3d419ca 184 PRINTS PR01576 Peptide deformylase signature 121 139 6.8E-31 T 06-07-2017 IPR023635 Peptide deformylase GTHT12_RS05570 54783bee4e193e263b44a84db3d419ca 184 PRINTS PR01576 Peptide deformylase signature 140 169 6.8E-31 T 06-07-2017 IPR023635 Peptide deformylase GTHT12_RS05570 54783bee4e193e263b44a84db3d419ca 184 PRINTS PR01576 Peptide deformylase signature 108 119 6.8E-31 T 06-07-2017 IPR023635 Peptide deformylase GTHT12_RS05570 54783bee4e193e263b44a84db3d419ca 184 SUPERFAMILY SSF56420 2 178 2.75E-62 T 06-07-2017 IPR023635 Peptide deformylase GTHT12_RS05570 54783bee4e193e263b44a84db3d419ca 184 Pfam PF01327 Polypeptide deformylase 4 171 1.0E-46 T 06-07-2017 IPR023635 Peptide deformylase GTHT12_RS05570 54783bee4e193e263b44a84db3d419ca 184 Gene3D G3DSA:3.90.45.10 3 175 1.3E-56 T 06-07-2017 IPR023635 Peptide deformylase GTHT12_RS05570 54783bee4e193e263b44a84db3d419ca 184 PIRSF PIRSF004749 1 184 5.6E-50 T 06-07-2017 IPR023635 Peptide deformylase GTHT12_RS05570 54783bee4e193e263b44a84db3d419ca 184 Hamap MF_00163 Peptide deformylase [def]. 3 182 27.995 T 06-07-2017 IPR023635 Peptide deformylase GTHT12_RS05570 54783bee4e193e263b44a84db3d419ca 184 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 175 5.4E-48 T 06-07-2017 IPR023635 Peptide deformylase GTHT12_RS00715 ae722923097908ba3244446ca392b885 103 SMART SM00739 2 29 3.1E-6 T 06-07-2017 IPR005824 KOW GTHT12_RS00715 ae722923097908ba3244446ca392b885 103 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 95 23.433 T 06-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00715 ae722923097908ba3244446ca392b885 103 Pfam PF00467 KOW motif 5 36 1.6E-9 T 06-07-2017 IPR005824 KOW GTHT12_RS00715 ae722923097908ba3244446ca392b885 103 SUPERFAMILY SSF50104 1 100 2.97E-40 T 06-07-2017 IPR008991 Translation protein SH3-like domain GTHT12_RS00715 ae722923097908ba3244446ca392b885 103 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 100 4.4E-32 T 06-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00715 ae722923097908ba3244446ca392b885 103 Gene3D G3DSA:2.30.30.30 1 90 1.7E-28 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 GTHT12_RS00715 ae722923097908ba3244446ca392b885 103 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 101 1.1E-42 T 06-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00715 ae722923097908ba3244446ca392b885 103 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 06-07-2017 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS09105 5a49f4e489068d28517b62a59ca1a10e 300 PIRSF PIRSF036480 17 300 7.5E-113 T 06-07-2017 GTHT12_RS09105 5a49f4e489068d28517b62a59ca1a10e 300 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 17 299 48.56 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 GTHT12_RS09105 5a49f4e489068d28517b62a59ca1a10e 300 SUPERFAMILY SSF55021 19 101 8.02E-19 T 06-07-2017 GTHT12_RS09105 5a49f4e489068d28517b62a59ca1a10e 300 Gene3D G3DSA:3.40.50.170 105 295 2.5E-58 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GTHT12_RS09105 5a49f4e489068d28517b62a59ca1a10e 300 Pfam PF01842 ACT domain 21 81 8.5E-11 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 GTHT12_RS09105 5a49f4e489068d28517b62a59ca1a10e 300 Gene3D G3DSA:3.30.70.260 18 98 5.6E-28 T 06-07-2017 GTHT12_RS09105 5a49f4e489068d28517b62a59ca1a10e 300 SUPERFAMILY SSF53328 105 299 3.92E-60 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GTHT12_RS09105 5a49f4e489068d28517b62a59ca1a10e 300 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 21 299 1.9E-124 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 GTHT12_RS09105 5a49f4e489068d28517b62a59ca1a10e 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 55 67 1.0E-62 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 GTHT12_RS09105 5a49f4e489068d28517b62a59ca1a10e 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 251 273 1.0E-62 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 GTHT12_RS09105 5a49f4e489068d28517b62a59ca1a10e 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 273 298 1.0E-62 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 GTHT12_RS09105 5a49f4e489068d28517b62a59ca1a10e 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 22 48 1.0E-62 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 GTHT12_RS09105 5a49f4e489068d28517b62a59ca1a10e 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 105 127 1.0E-62 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 GTHT12_RS09105 5a49f4e489068d28517b62a59ca1a10e 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 127 154 1.0E-62 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 GTHT12_RS09105 5a49f4e489068d28517b62a59ca1a10e 300 Pfam PF00551 Formyl transferase 105 280 4.9E-39 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GTHT12_RS18455 7bbe4d58990c0432299ea2cc46ef3c61 175 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 GTHT12_RS18455 7bbe4d58990c0432299ea2cc46ef3c61 175 SUPERFAMILY SSF55811 2 132 2.03E-24 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 GTHT12_RS18455 7bbe4d58990c0432299ea2cc46ef3c61 175 Pfam PF00293 NUDIX domain 2 124 7.1E-16 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 GTHT12_RS18455 7bbe4d58990c0432299ea2cc46ef3c61 175 Gene3D G3DSA:3.90.79.10 2 136 9.4E-27 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 GTHT12_RS11700 834162ae79f0101e92b1da3a78e19322 74 Gene3D G3DSA:2.60.40.50 2 73 5.1E-43 T 06-07-2017 IPR023558 Tryptophan RNA-binding attenuator protein domain GTHT12_RS11700 834162ae79f0101e92b1da3a78e19322 74 Pfam PF02081 Tryptophan RNA-binding attenuator protein 4 71 2.0E-41 T 06-07-2017 IPR023558 Tryptophan RNA-binding attenuator protein domain GTHT12_RS11700 834162ae79f0101e92b1da3a78e19322 74 Hamap MF_00798 Transcription attenuation protein MtrB [mtrB]. 1 71 27.27 T 06-07-2017 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 GTHT12_RS11700 834162ae79f0101e92b1da3a78e19322 74 SUPERFAMILY SSF51219 5 71 1.73E-35 T 06-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain GTHT12_RS11700 834162ae79f0101e92b1da3a78e19322 74 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 56 72 1.2E-35 T 06-07-2017 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 GTHT12_RS11700 834162ae79f0101e92b1da3a78e19322 74 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 7 24 1.2E-35 T 06-07-2017 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 GTHT12_RS11700 834162ae79f0101e92b1da3a78e19322 74 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 40 56 1.2E-35 T 06-07-2017 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 GTHT12_RS11700 834162ae79f0101e92b1da3a78e19322 74 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 24 40 1.2E-35 T 06-07-2017 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 GTHT12_RS10100 81bd1fc6def632af48f725c59963f639 360 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 34 148 1.5E-21 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 GTHT12_RS10100 81bd1fc6def632af48f725c59963f639 360 Gene3D G3DSA:3.30.360.10 310 354 1.5E-33 T 06-07-2017 GTHT12_RS10100 81bd1fc6def632af48f725c59963f639 360 Gene3D G3DSA:3.30.360.10 171 277 1.5E-33 T 06-07-2017 GTHT12_RS10100 81bd1fc6def632af48f725c59963f639 360 Gene3D G3DSA:3.40.50.720 33 170 6.6E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS10100 81bd1fc6def632af48f725c59963f639 360 SUPERFAMILY SSF51735 33 198 7.23E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS10100 81bd1fc6def632af48f725c59963f639 360 SUPERFAMILY SSF55347 155 324 4.25E-38 T 06-07-2017 GTHT12_RS08820 7c6f7fd6e52be7cca74de068b90eb9f1 94 SMART SM00448 4 94 0.0025 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS08820 7c6f7fd6e52be7cca74de068b90eb9f1 94 SUPERFAMILY SSF52172 2 90 6.69E-23 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS08820 7c6f7fd6e52be7cca74de068b90eb9f1 94 Gene3D G3DSA:3.40.50.2300 3 89 2.7E-22 T 06-07-2017 GTHT12_RS08820 7c6f7fd6e52be7cca74de068b90eb9f1 94 Pfam PF00072 Response regulator receiver domain 6 88 1.5E-16 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS11050 688eb9ac67e7a4edec4b2f08c56e9229 529 Gene3D G3DSA:3.40.190.10 203 307 3.7E-29 T 06-07-2017 GTHT12_RS11050 688eb9ac67e7a4edec4b2f08c56e9229 529 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 87 444 1.6E-79 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain GTHT12_RS11050 688eb9ac67e7a4edec4b2f08c56e9229 529 Gene3D G3DSA:3.10.105.10 308 499 3.4E-36 T 06-07-2017 GTHT12_RS11050 688eb9ac67e7a4edec4b2f08c56e9229 529 SUPERFAMILY SSF53850 41 516 1.43E-117 T 06-07-2017 GTHT12_RS11050 688eb9ac67e7a4edec4b2f08c56e9229 529 PIRSF PIRSF002741 2 517 1.2E-93 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 GTHT12_RS11050 688eb9ac67e7a4edec4b2f08c56e9229 529 Gene3D G3DSA:3.90.76.10 54 202 7.8E-43 T 06-07-2017 GTHT12_RS01845 d8c8a4d5f516096e53966099a0f6178b 265 Gene3D G3DSA:3.90.226.10 5 204 1.6E-66 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS01845 d8c8a4d5f516096e53966099a0f6178b 265 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 105 125 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 GTHT12_RS01845 d8c8a4d5f516096e53966099a0f6178b 265 Gene3D G3DSA:1.10.12.10 206 255 5.2E-21 T 06-07-2017 IPR014748 Crontonase, C-terminal GTHT12_RS01845 d8c8a4d5f516096e53966099a0f6178b 265 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 262 1.3E-75 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 GTHT12_RS01845 d8c8a4d5f516096e53966099a0f6178b 265 SUPERFAMILY SSF52096 2 262 1.9E-77 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS01845 d8c8a4d5f516096e53966099a0f6178b 265 TIGRFAM TIGR01929 menB: naphthoate synthase 3 263 1.4E-110 T 06-07-2017 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 GTHT12_RS01845 d8c8a4d5f516096e53966099a0f6178b 265 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 1 265 46.744 T 06-07-2017 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 GTHT12_RS02735 1de6252d74c4b320bb162008766a61fa 153 Pfam PF15565 Immunity protein 30 13 112 6.9E-28 T 06-07-2017 IPR029084 Immunity protein 30 GTHT12_RS00085 8747e05fcb696d790573af02ba5aca3f 195 Gene3D G3DSA:3.40.50.880 1 191 5.0E-79 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS00085 8747e05fcb696d790573af02ba5aca3f 195 PIRSF PIRSF005639 1 190 3.8E-75 T 06-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 GTHT12_RS00085 8747e05fcb696d790573af02ba5aca3f 195 SUPERFAMILY SSF52317 2 188 5.14E-56 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS00085 8747e05fcb696d790573af02ba5aca3f 195 Pfam PF01174 SNO glutamine amidotransferase family 5 187 6.7E-74 T 06-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 GTHT12_RS00085 8747e05fcb696d790573af02ba5aca3f 195 ProSitePatterns PS01236 PdxT/SNO family family signature. 40 50 - T 06-07-2017 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 GTHT12_RS00085 8747e05fcb696d790573af02ba5aca3f 195 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 2 184 1.3E-86 T 06-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 GTHT12_RS00085 8747e05fcb696d790573af02ba5aca3f 195 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 3 185 39.318 T 06-07-2017 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 GTHT12_RS17590 322fa0b6823d3149c9f3509fcdc2127e 424 SUPERFAMILY SSF68912 4 49 8.24E-11 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 GTHT12_RS17590 322fa0b6823d3149c9f3509fcdc2127e 424 Gene3D G3DSA:3.40.50.300 131 410 1.2E-97 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17590 322fa0b6823d3149c9f3509fcdc2127e 424 SMART SM00357 54 119 4.0E-20 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 GTHT12_RS17590 322fa0b6823d3149c9f3509fcdc2127e 424 Pfam PF07497 Rho termination factor, RNA-binding domain 53 126 2.1E-31 T 06-07-2017 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 GTHT12_RS17590 322fa0b6823d3149c9f3509fcdc2127e 424 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 157 361 1.4E-18 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GTHT12_RS17590 322fa0b6823d3149c9f3509fcdc2127e 424 SMART SM00382 168 353 1.9E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS17590 322fa0b6823d3149c9f3509fcdc2127e 424 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 415 226.239 T 06-07-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 GTHT12_RS17590 322fa0b6823d3149c9f3509fcdc2127e 424 Pfam PF07498 Rho termination factor, N-terminal domain 8 49 1.3E-16 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 GTHT12_RS17590 322fa0b6823d3149c9f3509fcdc2127e 424 SUPERFAMILY SSF50249 50 114 2.63E-7 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS17590 322fa0b6823d3149c9f3509fcdc2127e 424 SMART SM00959 7 49 1.1E-16 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 GTHT12_RS17590 322fa0b6823d3149c9f3509fcdc2127e 424 Gene3D G3DSA:2.40.50.140 5 126 1.6E-45 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS17590 322fa0b6823d3149c9f3509fcdc2127e 424 SUPERFAMILY SSF52540 91 369 2.19E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17590 322fa0b6823d3149c9f3509fcdc2127e 424 TIGRFAM TIGR00767 rho: transcription termination factor Rho 5 413 4.7E-207 T 06-07-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 GTHT12_RS11310 e9e026b46f9445435d5defe70e1c7efd 83 Gene3D G3DSA:3.40.630.30 16 83 1.4E-6 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS11310 e9e026b46f9445435d5defe70e1c7efd 83 SUPERFAMILY SSF55729 17 83 4.53E-6 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS06235 165b6c95f4a5c6f24cbeef79bbdec762 172 SUPERFAMILY SSF50447 4 92 2.05E-22 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain GTHT12_RS06235 165b6c95f4a5c6f24cbeef79bbdec762 172 Pfam PF05239 PRC-barrel domain 97 171 4.0E-14 T 06-07-2017 IPR027275 PRC-barrel domain GTHT12_RS06235 165b6c95f4a5c6f24cbeef79bbdec762 172 SUPERFAMILY SSF50346 100 170 9.16E-20 T 06-07-2017 IPR011033 PRC-barrel-like GTHT12_RS06235 165b6c95f4a5c6f24cbeef79bbdec762 172 Pfam PF01782 RimM N-terminal domain 7 91 5.1E-25 T 06-07-2017 IPR002676 RimM protein GO:0006364 GTHT12_RS06235 165b6c95f4a5c6f24cbeef79bbdec762 172 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 4 170 23.981 T 06-07-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 GTHT12_RS06235 165b6c95f4a5c6f24cbeef79bbdec762 172 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 4 170 2.0E-53 T 06-07-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 GTHT12_RS06235 165b6c95f4a5c6f24cbeef79bbdec762 172 Gene3D G3DSA:2.40.30.60 2 92 4.4E-16 T 06-07-2017 IPR002676 RimM protein GO:0006364 GTHT12_RS06235 165b6c95f4a5c6f24cbeef79bbdec762 172 Gene3D G3DSA:2.30.30.240 100 170 4.4E-24 T 06-07-2017 GTHT12_RS18700 ae7fbd2f6cb08fd6bf2677f810f87ed9 291 Gene3D G3DSA:1.10.3720.10 11 279 4.8E-51 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS18700 ae7fbd2f6cb08fd6bf2677f810f87ed9 291 SUPERFAMILY SSF161098 7 291 1.8E-58 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS18700 ae7fbd2f6cb08fd6bf2677f810f87ed9 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 285 4.6E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 Gene3D G3DSA:2.40.33.10 74 169 3.5E-31 T 06-07-2017 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 PRINTS PR01050 Pyruvate kinase family signature 245 269 1.5E-81 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 PRINTS PR01050 Pyruvate kinase family signature 270 294 1.5E-81 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 PRINTS PR01050 Pyruvate kinase family signature 60 76 1.5E-81 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 PRINTS PR01050 Pyruvate kinase family signature 295 313 1.5E-81 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 PRINTS PR01050 Pyruvate kinase family signature 187 201 1.5E-81 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 PRINTS PR01050 Pyruvate kinase family signature 218 244 1.5E-81 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 PRINTS PR01050 Pyruvate kinase family signature 314 330 1.5E-81 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 474 6.0E-192 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 ProSitePatterns PS00110 Pyruvate kinase active site signature. 216 228 - T 06-07-2017 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 Pfam PF00391 PEP-utilising enzyme, mobile domain 508 576 5.6E-23 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 Gene3D G3DSA:3.40.1380.20 328 471 1.1E-50 T 06-07-2017 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 SUPERFAMILY SSF52935 324 474 3.01E-43 T 06-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 Pfam PF00224 Pyruvate kinase, barrel domain 3 345 5.0E-163 T 06-07-2017 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 SUPERFAMILY SSF52009 467 584 1.31E-31 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 Pfam PF02887 Pyruvate kinase, alpha/beta domain 359 472 5.9E-37 T 06-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 Gene3D G3DSA:3.50.30.10 472 580 2.5E-28 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 SUPERFAMILY SSF51621 157 343 9.42E-105 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 SUPERFAMILY SSF51621 2 75 9.42E-105 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 Gene3D G3DSA:3.20.20.60 170 327 7.0E-114 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 Gene3D G3DSA:3.20.20.60 3 73 7.0E-114 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GTHT12_RS14250 a40bada88df568eae02399b62676e05c 587 SUPERFAMILY SSF50800 71 168 5.06E-27 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain GTHT12_RS01855 a8a0b74cdde5dc758b2531db595bf1b6 248 SUPERFAMILY SSF51735 2 247 1.21E-85 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS01855 a8a0b74cdde5dc758b2531db595bf1b6 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 9.7E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01855 a8a0b74cdde5dc758b2531db595bf1b6 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 9.7E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01855 a8a0b74cdde5dc758b2531db595bf1b6 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 9.7E-14 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01855 a8a0b74cdde5dc758b2531db595bf1b6 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GTHT12_RS01855 a8a0b74cdde5dc758b2531db595bf1b6 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 246 6.4E-69 T 06-07-2017 GTHT12_RS01855 a8a0b74cdde5dc758b2531db595bf1b6 248 Gene3D G3DSA:3.40.50.720 1 247 2.6E-87 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS01855 a8a0b74cdde5dc758b2531db595bf1b6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 5.6E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01855 a8a0b74cdde5dc758b2531db595bf1b6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 5.6E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01855 a8a0b74cdde5dc758b2531db595bf1b6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 5.6E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01855 a8a0b74cdde5dc758b2531db595bf1b6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 5.6E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01855 a8a0b74cdde5dc758b2531db595bf1b6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 5.6E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01855 a8a0b74cdde5dc758b2531db595bf1b6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 5.6E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS03875 7a35b245b3a1c9e298c65dd8122f7293 182 Pfam PF10949 Protein of unknown function (DUF2777) 4 179 5.9E-73 T 06-07-2017 IPR024488 Protein of unknown function DUF2777 GTHT12_RS03875 7a35b245b3a1c9e298c65dd8122f7293 182 ProDom PD106196 YISN IG BH1722 5 174 3.0E-77 T 06-07-2017 IPR024488 Protein of unknown function DUF2777 GTHT12_RS07400 6e2283371e52483d60c4275583e6693e 697 Gene3D G3DSA:2.60.40.1080 70 107 7.8E-7 T 06-07-2017 GTHT12_RS07400 6e2283371e52483d60c4275583e6693e 697 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 409 426 - T 06-07-2017 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 GTHT12_RS07400 6e2283371e52483d60c4275583e6693e 697 SUPERFAMILY SSF49373 50 106 3.22E-8 T 06-07-2017 IPR008964 Invasin/intimin cell-adhesion fragments GTHT12_RS07400 6e2283371e52483d60c4275583e6693e 697 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 531 697 4.8E-15 T 06-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 GTHT12_RS07400 6e2283371e52483d60c4275583e6693e 697 Gene3D G3DSA:3.20.20.300 160 504 3.0E-120 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 GTHT12_RS07400 6e2283371e52483d60c4275583e6693e 697 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 154 488 1.9E-116 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 GTHT12_RS07400 6e2283371e52483d60c4275583e6693e 697 SUPERFAMILY SSF51445 141 530 4.0E-111 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS07400 6e2283371e52483d60c4275583e6693e 697 PRINTS PR00133 Glycosyl hydrolase family 3 signature 321 337 1.5E-6 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 GTHT12_RS07400 6e2283371e52483d60c4275583e6693e 697 PRINTS PR00133 Glycosyl hydrolase family 3 signature 409 427 1.5E-6 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 GTHT12_RS07400 6e2283371e52483d60c4275583e6693e 697 PRINTS PR00133 Glycosyl hydrolase family 3 signature 243 262 1.5E-6 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 GTHT12_RS07400 6e2283371e52483d60c4275583e6693e 697 Gene3D G3DSA:3.40.50.1700 516 696 4.4E-19 T 06-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 GTHT12_RS07400 6e2283371e52483d60c4275583e6693e 697 SUPERFAMILY SSF52279 531 697 1.06E-18 T 06-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 GTHT12_RS14940 8dd05faff5de01d96bcdc54ca10e5a34 666 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 533 631 4.8E-19 T 06-07-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 GTHT12_RS14940 8dd05faff5de01d96bcdc54ca10e5a34 666 SUPERFAMILY SSF51011 528 632 1.62E-32 T 06-07-2017 GTHT12_RS14940 8dd05faff5de01d96bcdc54ca10e5a34 666 Gene3D G3DSA:2.60.40.10 28 137 1.9E-36 T 06-07-2017 IPR013783 Immunoglobulin-like fold GTHT12_RS14940 8dd05faff5de01d96bcdc54ca10e5a34 666 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 25 630 3.6E-270 T 06-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 GTHT12_RS14940 8dd05faff5de01d96bcdc54ca10e5a34 666 SUPERFAMILY SSF51445 99 521 2.59E-115 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS14940 8dd05faff5de01d96bcdc54ca10e5a34 666 Gene3D G3DSA:2.60.40.1180 528 631 7.2E-34 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta GTHT12_RS14940 8dd05faff5de01d96bcdc54ca10e5a34 666 SMART SM00642 166 497 6.0E-9 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GTHT12_RS14940 8dd05faff5de01d96bcdc54ca10e5a34 666 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 40 122 1.0E-22 T 06-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 GTHT12_RS14940 8dd05faff5de01d96bcdc54ca10e5a34 666 SUPERFAMILY SSF81296 51 122 1.4E-10 T 06-07-2017 IPR014756 Immunoglobulin E-set GTHT12_RS14940 8dd05faff5de01d96bcdc54ca10e5a34 666 PIRSF PIRSF000463 7 642 7.5E-272 T 06-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 GTHT12_RS14940 8dd05faff5de01d96bcdc54ca10e5a34 666 Pfam PF00128 Alpha amylase, catalytic domain 190 289 4.5E-11 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GTHT12_RS14940 8dd05faff5de01d96bcdc54ca10e5a34 666 Gene3D G3DSA:3.20.20.80 154 516 2.3E-92 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS14940 8dd05faff5de01d96bcdc54ca10e5a34 666 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 13 632 41.062 T 06-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 GTHT12_RS12360 2b60b2863c92617a9325044c60bb91b1 373 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 72 81 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 GTHT12_RS12360 2b60b2863c92617a9325044c60bb91b1 373 Gene3D G3DSA:3.40.630.10 288 372 2.1E-77 T 06-07-2017 GTHT12_RS12360 2b60b2863c92617a9325044c60bb91b1 373 Gene3D G3DSA:3.40.630.10 1 178 2.1E-77 T 06-07-2017 GTHT12_RS12360 2b60b2863c92617a9325044c60bb91b1 373 SUPERFAMILY SSF53187 288 371 1.53E-65 T 06-07-2017 GTHT12_RS12360 2b60b2863c92617a9325044c60bb91b1 373 SUPERFAMILY SSF53187 5 178 1.53E-65 T 06-07-2017 GTHT12_RS12360 2b60b2863c92617a9325044c60bb91b1 373 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 105 143 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 GTHT12_RS12360 2b60b2863c92617a9325044c60bb91b1 373 Pfam PF07687 Peptidase dimerisation domain 181 274 1.1E-15 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS12360 2b60b2863c92617a9325044c60bb91b1 373 Gene3D G3DSA:3.30.70.360 180 284 3.6E-25 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS12360 2b60b2863c92617a9325044c60bb91b1 373 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 6 368 6.4E-164 T 06-07-2017 IPR010162 Peptidase M20B, peptidase T-like GTHT12_RS12360 2b60b2863c92617a9325044c60bb91b1 373 SUPERFAMILY SSF55031 180 285 4.45E-22 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS12360 2b60b2863c92617a9325044c60bb91b1 373 Pfam PF01546 Peptidase family M20/M25/M40 74 368 2.9E-24 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 GTHT12_RS00385 3ff48da0e52ff954572cd2b466e3fa0b 258 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 4 249 5.6E-84 T 06-07-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 GTHT12_RS00385 3ff48da0e52ff954572cd2b466e3fa0b 258 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 254 37.452 T 06-07-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 GTHT12_RS00385 3ff48da0e52ff954572cd2b466e3fa0b 258 SUPERFAMILY SSF53067 124 253 1.74E-39 T 06-07-2017 GTHT12_RS00385 3ff48da0e52ff954572cd2b466e3fa0b 258 Gene3D G3DSA:3.30.420.40 94 256 4.0E-53 T 06-07-2017 GTHT12_RS00385 3ff48da0e52ff954572cd2b466e3fa0b 258 Pfam PF03309 Type III pantothenate kinase 3 205 1.6E-73 T 06-07-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 GTHT12_RS00385 3ff48da0e52ff954572cd2b466e3fa0b 258 SUPERFAMILY SSF53067 1 122 8.49E-39 T 06-07-2017 GTHT12_RS04810 94971bf65bcf16cb3c5009dc732b155b 635 SUPERFAMILY SSF52402 229 380 2.1E-93 T 06-07-2017 GTHT12_RS04810 94971bf65bcf16cb3c5009dc732b155b 635 SUPERFAMILY SSF52402 467 605 2.1E-93 T 06-07-2017 GTHT12_RS04810 94971bf65bcf16cb3c5009dc732b155b 635 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 547 3.9E-174 T 06-07-2017 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 GTHT12_RS04810 94971bf65bcf16cb3c5009dc732b155b 635 SUPERFAMILY SSF56235 1 224 2.06E-63 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal GTHT12_RS04810 94971bf65bcf16cb3c5009dc732b155b 635 Pfam PF13537 Glutamine amidotransferase domain 51 168 6.3E-47 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain GTHT12_RS04810 94971bf65bcf16cb3c5009dc732b155b 635 Gene3D G3DSA:3.40.50.620 463 610 6.5E-107 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS04810 94971bf65bcf16cb3c5009dc732b155b 635 Gene3D G3DSA:3.40.50.620 224 376 6.5E-107 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS04810 94971bf65bcf16cb3c5009dc732b155b 635 Gene3D G3DSA:3.60.20.10 1 223 1.2E-72 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal GTHT12_RS04810 94971bf65bcf16cb3c5009dc732b155b 635 PIRSF PIRSF001589 1 628 6.0E-206 T 06-07-2017 GTHT12_RS04810 94971bf65bcf16cb3c5009dc732b155b 635 Pfam PF00733 Asparagine synthase 240 610 3.9E-115 T 06-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 GTHT12_RS17485 57fac3209d894738d34b4b9443bc288e 502 Gene3D G3DSA:2.40.30.20 1 93 1.3E-39 T 06-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 GTHT12_RS17485 57fac3209d894738d34b4b9443bc288e 502 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 494 4.9E-47 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GTHT12_RS17485 57fac3209d894738d34b4b9443bc288e 502 Gene3D G3DSA:1.20.150.20 372 498 9.0E-52 T 06-07-2017 GTHT12_RS17485 57fac3209d894738d34b4b9443bc288e 502 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 499 52.328 T 06-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 GTHT12_RS17485 57fac3209d894738d34b4b9443bc288e 502 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 92 2.4E-21 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GTHT12_RS17485 57fac3209d894738d34b4b9443bc288e 502 SUPERFAMILY SSF52540 95 370 1.12E-98 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17485 57fac3209d894738d34b4b9443bc288e 502 PIRSF PIRSF039088 1 501 6.1E-256 T 06-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 GTHT12_RS17485 57fac3209d894738d34b4b9443bc288e 502 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 06-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GTHT12_RS17485 57fac3209d894738d34b4b9443bc288e 502 SUPERFAMILY SSF50615 10 94 9.42E-32 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GTHT12_RS17485 57fac3209d894738d34b4b9443bc288e 502 SUPERFAMILY SSF47917 372 500 4.19E-48 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GTHT12_RS17485 57fac3209d894738d34b4b9443bc288e 502 Gene3D G3DSA:3.40.50.300 94 371 1.4E-116 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17485 57fac3209d894738d34b4b9443bc288e 502 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 6.5E-74 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GTHT12_RS17485 57fac3209d894738d34b4b9443bc288e 502 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 499 7.2E-262 T 06-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 GTHT12_RS02435 9f408d5d9eb5dfbadd862569e4d5a504 256 Gene3D G3DSA:3.40.800.10 29 213 1.1E-15 T 06-07-2017 IPR023696 Ureohydrolase domain GTHT12_RS02435 9f408d5d9eb5dfbadd862569e4d5a504 256 SUPERFAMILY SSF52768 28 216 2.88E-20 T 06-07-2017 GTHT12_RS02435 9f408d5d9eb5dfbadd862569e4d5a504 256 Pfam PF00491 Arginase family 29 213 4.1E-10 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 GTHT12_RS11395 ca62706b4d59383a3802a8482ed3e036 394 Gene3D G3DSA:3.30.70.890 210 384 8.9E-58 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain GTHT12_RS11395 ca62706b4d59383a3802a8482ed3e036 394 PRINTS PR00473 Galactokinase signature 268 282 1.3E-27 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 GTHT12_RS11395 ca62706b4d59383a3802a8482ed3e036 394 PRINTS PR00473 Galactokinase signature 27 45 1.3E-27 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 GTHT12_RS11395 ca62706b4d59383a3802a8482ed3e036 394 PRINTS PR00473 Galactokinase signature 112 130 1.3E-27 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 GTHT12_RS11395 ca62706b4d59383a3802a8482ed3e036 394 PRINTS PR00473 Galactokinase signature 92 103 1.3E-27 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 GTHT12_RS11395 ca62706b4d59383a3802a8482ed3e036 394 Pfam PF00288 GHMP kinases N terminal domain 115 181 1.8E-15 T 06-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 GTHT12_RS11395 ca62706b4d59383a3802a8482ed3e036 394 PIRSF PIRSF000530 1 388 3.0E-119 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 GTHT12_RS11395 ca62706b4d59383a3802a8482ed3e036 394 SUPERFAMILY SSF55060 205 384 1.4E-53 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain GTHT12_RS11395 ca62706b4d59383a3802a8482ed3e036 394 Hamap MF_00246 Galactokinase [galK]. 25 385 45.769 T 06-07-2017 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 GTHT12_RS11395 ca62706b4d59383a3802a8482ed3e036 394 Pfam PF08544 GHMP kinases C terminal 285 361 3.1E-9 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain GTHT12_RS11395 ca62706b4d59383a3802a8482ed3e036 394 ProSitePatterns PS00106 Galactokinase signature. 27 38 - T 06-07-2017 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 GTHT12_RS11395 ca62706b4d59383a3802a8482ed3e036 394 Gene3D G3DSA:3.30.230.10 3 209 7.7E-73 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GTHT12_RS11395 ca62706b4d59383a3802a8482ed3e036 394 TIGRFAM TIGR00131 gal_kin: galactokinase 4 385 3.4E-121 T 06-07-2017 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 GTHT12_RS11395 ca62706b4d59383a3802a8482ed3e036 394 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 121 132 - T 06-07-2017 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 GTHT12_RS11395 ca62706b4d59383a3802a8482ed3e036 394 PRINTS PR00959 Mevalonate kinase family signature 25 49 1.3E-43 T 06-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 GTHT12_RS11395 ca62706b4d59383a3802a8482ed3e036 394 PRINTS PR00959 Mevalonate kinase family signature 119 141 1.3E-43 T 06-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 GTHT12_RS11395 ca62706b4d59383a3802a8482ed3e036 394 PRINTS PR00959 Mevalonate kinase family signature 162 181 1.3E-43 T 06-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 GTHT12_RS11395 ca62706b4d59383a3802a8482ed3e036 394 PRINTS PR00959 Mevalonate kinase family signature 332 349 1.3E-43 T 06-07-2017 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 GTHT12_RS11395 ca62706b4d59383a3802a8482ed3e036 394 Pfam PF10509 Galactokinase galactose-binding signature 8 57 2.3E-21 T 06-07-2017 IPR019539 Galactokinase galactose-binding domain KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 GTHT12_RS11395 ca62706b4d59383a3802a8482ed3e036 394 SUPERFAMILY SSF54211 3 202 4.93E-60 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS09645 c3c1094397ec11e854084d2d712efdfa 250 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 06-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 GTHT12_RS09645 c3c1094397ec11e854084d2d712efdfa 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 6.1E-8 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 GTHT12_RS09645 c3c1094397ec11e854084d2d712efdfa 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 6.1E-8 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 GTHT12_RS09645 c3c1094397ec11e854084d2d712efdfa 250 Gene3D G3DSA:1.10.10.10 8 56 7.6E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS09645 c3c1094397ec11e854084d2d712efdfa 250 Pfam PF00455 DeoR C terminal sensor domain 76 230 1.8E-50 T 06-07-2017 IPR014036 DeoR C-terminal sensor domain GTHT12_RS09645 c3c1094397ec11e854084d2d712efdfa 250 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 1.7E-16 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 GTHT12_RS09645 c3c1094397ec11e854084d2d712efdfa 250 SUPERFAMILY SSF100950 74 223 1.26E-34 T 06-07-2017 GTHT12_RS09645 c3c1094397ec11e854084d2d712efdfa 250 SMART SM00420 6 58 2.5E-18 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 GTHT12_RS09645 c3c1094397ec11e854084d2d712efdfa 250 Gene3D G3DSA:3.40.50.1360 76 214 9.0E-14 T 06-07-2017 GTHT12_RS09645 c3c1094397ec11e854084d2d712efdfa 250 SUPERFAMILY SSF46785 4 77 8.09E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS09645 c3c1094397ec11e854084d2d712efdfa 250 SMART SM01134 73 231 9.4E-70 T 06-07-2017 GTHT12_RS14560 4f2d092c3694df0185f9f4c5d4f8466e 419 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 161 176 2.5E-33 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 GTHT12_RS14560 4f2d092c3694df0185f9f4c5d4f8466e 419 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 216 228 2.5E-33 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 GTHT12_RS14560 4f2d092c3694df0185f9f4c5d4f8466e 419 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 2.5E-33 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 GTHT12_RS14560 4f2d092c3694df0185f9f4c5d4f8466e 419 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 182 204 2.5E-33 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 GTHT12_RS14560 4f2d092c3694df0185f9f4c5d4f8466e 419 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 418 3.5E-145 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 GTHT12_RS14560 4f2d092c3694df0185f9f4c5d4f8466e 419 Gene3D G3DSA:3.40.50.620 2 232 3.7E-103 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS14560 4f2d092c3694df0185f9f4c5d4f8466e 419 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 418 47.325 T 06-07-2017 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 GTHT12_RS14560 4f2d092c3694df0185f9f4c5d4f8466e 419 SMART SM00363 352 415 1.4E-6 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS14560 4f2d092c3694df0185f9f4c5d4f8466e 419 Pfam PF00579 tRNA synthetases class I (W and Y) 28 323 1.2E-95 T 06-07-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS14560 4f2d092c3694df0185f9f4c5d4f8466e 419 SUPERFAMILY SSF52374 1 323 3.2E-112 T 06-07-2017 GTHT12_RS14560 4f2d092c3694df0185f9f4c5d4f8466e 419 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS14560 4f2d092c3694df0185f9f4c5d4f8466e 419 SUPERFAMILY SSF55174 321 418 1.7E-26 T 06-07-2017 GTHT12_RS14560 4f2d092c3694df0185f9f4c5d4f8466e 419 Gene3D G3DSA:1.10.240.10 233 316 7.1E-46 T 06-07-2017 GTHT12_RS14560 4f2d092c3694df0185f9f4c5d4f8466e 419 Pfam PF01479 S4 domain 353 394 5.1E-9 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS14560 4f2d092c3694df0185f9f4c5d4f8466e 419 Gene3D G3DSA:3.10.290.10 317 418 8.8E-33 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS13455 37e9f0b9b6d21a93f4221fd826c108fe 590 SUPERFAMILY SSF55681 425 584 1.37E-110 T 06-07-2017 GTHT12_RS13455 37e9f0b9b6d21a93f4221fd826c108fe 590 SUPERFAMILY SSF55681 114 296 1.37E-110 T 06-07-2017 GTHT12_RS13455 37e9f0b9b6d21a93f4221fd826c108fe 590 Gene3D G3DSA:3.30.1360.30 281 414 1.8E-50 T 06-07-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 GTHT12_RS13455 37e9f0b9b6d21a93f4221fd826c108fe 590 Pfam PF01336 OB-fold nucleic acid binding domain 19 104 5.2E-15 T 06-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 GTHT12_RS13455 37e9f0b9b6d21a93f4221fd826c108fe 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 475 491 3.0E-26 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS13455 37e9f0b9b6d21a93f4221fd826c108fe 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 211 224 3.0E-26 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS13455 37e9f0b9b6d21a93f4221fd826c108fe 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 519 533 3.0E-26 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS13455 37e9f0b9b6d21a93f4221fd826c108fe 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 194 206 3.0E-26 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS13455 37e9f0b9b6d21a93f4221fd826c108fe 590 Gene3D G3DSA:2.40.50.140 3 110 1.6E-36 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS13455 37e9f0b9b6d21a93f4221fd826c108fe 590 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 2 584 2.3E-258 T 06-07-2017 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 Reactome: R-HSA-379726 GTHT12_RS13455 37e9f0b9b6d21a93f4221fd826c108fe 590 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 2 564 37.586 T 06-07-2017 GTHT12_RS13455 37e9f0b9b6d21a93f4221fd826c108fe 590 Gene3D G3DSA:3.30.930.10 135 280 9.6E-118 T 06-07-2017 GTHT12_RS13455 37e9f0b9b6d21a93f4221fd826c108fe 590 Gene3D G3DSA:3.30.930.10 415 584 9.6E-118 T 06-07-2017 GTHT12_RS13455 37e9f0b9b6d21a93f4221fd826c108fe 590 SUPERFAMILY SSF55261 293 420 1.11E-41 T 06-07-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 GTHT12_RS13455 37e9f0b9b6d21a93f4221fd826c108fe 590 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 558 4.3E-110 T 06-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS13455 37e9f0b9b6d21a93f4221fd826c108fe 590 Pfam PF02938 GAD domain 312 406 3.2E-31 T 06-07-2017 IPR029351 GAD domain Reactome: R-HSA-379726 GTHT12_RS13455 37e9f0b9b6d21a93f4221fd826c108fe 590 SUPERFAMILY SSF50249 3 107 2.67E-31 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS17675 6abbd29748e742d7298504c50037d8bc 55 Pfam PF07235 Protein of unknown function (DUF1427) 4 46 1.1E-5 T 06-07-2017 IPR009872 Protein of unknown function DUF1427 GTHT12_RS17675 6abbd29748e742d7298504c50037d8bc 55 TIGRFAM TIGR03510 XapX: XapX domain 3 50 4.1E-21 T 06-07-2017 IPR020017 XapX domain GTHT12_RS13840 af5408558b4939c0998ae1a5599aa003 558 Gene3D G3DSA:3.40.50.300 64 254 2.8E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13840 af5408558b4939c0998ae1a5599aa003 558 SMART SM00382 89 267 7.5E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS13840 af5408558b4939c0998ae1a5599aa003 558 Gene3D G3DSA:1.10.8.60 255 315 6.5E-7 T 06-07-2017 GTHT12_RS13840 af5408558b4939c0998ae1a5599aa003 558 SUPERFAMILY SSF52540 55 204 3.78E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13840 af5408558b4939c0998ae1a5599aa003 558 SUPERFAMILY SSF52540 235 328 3.78E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13840 af5408558b4939c0998ae1a5599aa003 558 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 344 529 1.7E-31 T 06-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 GTHT12_RS13840 af5408558b4939c0998ae1a5599aa003 558 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 442 450 - T 06-07-2017 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 GTHT12_RS13840 af5408558b4939c0998ae1a5599aa003 558 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 352 368 7.0E-31 T 06-07-2017 GTHT12_RS13840 af5408558b4939c0998ae1a5599aa003 558 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 97 116 7.0E-31 T 06-07-2017 GTHT12_RS13840 af5408558b4939c0998ae1a5599aa003 558 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 439 458 7.0E-31 T 06-07-2017 GTHT12_RS13840 af5408558b4939c0998ae1a5599aa003 558 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 469 488 7.0E-31 T 06-07-2017 GTHT12_RS13840 af5408558b4939c0998ae1a5599aa003 558 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 492 510 7.0E-31 T 06-07-2017 GTHT12_RS13840 af5408558b4939c0998ae1a5599aa003 558 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 93 266 1.5E-18 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 GTHT12_RS13840 af5408558b4939c0998ae1a5599aa003 558 Gene3D G3DSA:3.30.230.10 349 534 6.5E-49 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GTHT12_RS13840 af5408558b4939c0998ae1a5599aa003 558 SUPERFAMILY SSF54211 351 535 1.9E-41 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS13840 af5408558b4939c0998ae1a5599aa003 558 TIGRFAM TIGR02902 spore_lonB: ATP-dependent protease LonB 5 532 6.1E-282 T 06-07-2017 IPR014251 Sporulation protease LonB GTHT12_RS05585 f73f0abc8debf77cab1e2c1aaf74ae2c 436 SUPERFAMILY SSF52777 196 434 1.02E-89 T 06-07-2017 GTHT12_RS05585 f73f0abc8debf77cab1e2c1aaf74ae2c 436 Pfam PF02817 e3 binding domain 131 165 1.1E-15 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS05585 f73f0abc8debf77cab1e2c1aaf74ae2c 436 Pfam PF00364 Biotin-requiring enzyme 4 76 2.8E-25 T 06-07-2017 IPR000089 Biotin/lipoyl attachment GTHT12_RS05585 f73f0abc8debf77cab1e2c1aaf74ae2c 436 Gene3D G3DSA:4.10.320.10 123 172 2.3E-22 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS05585 f73f0abc8debf77cab1e2c1aaf74ae2c 436 SUPERFAMILY SSF47005 125 170 9.29E-14 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS05585 f73f0abc8debf77cab1e2c1aaf74ae2c 436 Gene3D G3DSA:2.40.50.100 3 96 7.0E-31 T 06-07-2017 GTHT12_RS05585 f73f0abc8debf77cab1e2c1aaf74ae2c 436 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 GTHT12_RS05585 f73f0abc8debf77cab1e2c1aaf74ae2c 436 Gene3D G3DSA:3.30.559.10 198 434 1.6E-96 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 GTHT12_RS05585 f73f0abc8debf77cab1e2c1aaf74ae2c 436 SUPERFAMILY SSF51230 3 93 6.41E-28 T 06-07-2017 IPR011053 Single hybrid motif GTHT12_RS05585 f73f0abc8debf77cab1e2c1aaf74ae2c 436 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 206 434 4.5E-90 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS05820 46f79e2e38206dd5d2a0d8b85f8b5f46 192 Pfam PF13921 Myb-like DNA-binding domain 9 62 1.1E-6 T 06-07-2017 GTHT12_RS05820 46f79e2e38206dd5d2a0d8b85f8b5f46 192 Gene3D G3DSA:1.10.10.60 3 60 3.9E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS05820 46f79e2e38206dd5d2a0d8b85f8b5f46 192 SMART SM00717 5 59 7.5E-5 T 06-07-2017 IPR001005 SANT/Myb domain GTHT12_RS05820 46f79e2e38206dd5d2a0d8b85f8b5f46 192 SUPERFAMILY SSF46689 5 63 3.04E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS05820 46f79e2e38206dd5d2a0d8b85f8b5f46 192 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 4 177 1.1E-51 T 06-07-2017 IPR014243 Transcription factor, RsfA GTHT12_RS02905 bc2a5bc38ade956a63a6994253fc2f67 305 Pfam PF08338 Domain of unknown function (DUF1731) 246 292 9.3E-22 T 06-07-2017 IPR013549 Domain of unknown function DUF1731 GTHT12_RS02905 bc2a5bc38ade956a63a6994253fc2f67 305 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 288 2.4E-107 T 06-07-2017 IPR010099 Epimerase family protein SDR39U1 GTHT12_RS02905 bc2a5bc38ade956a63a6994253fc2f67 305 SUPERFAMILY SSF51735 2 293 1.01E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS02905 bc2a5bc38ade956a63a6994253fc2f67 305 Gene3D G3DSA:3.40.50.720 2 236 3.7E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS02905 bc2a5bc38ade956a63a6994253fc2f67 305 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 211 4.1E-14 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 GTHT12_RS02340 331466f6992c3971eb8f88c612f41d08 504 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 2 497 2.1E-216 T 06-07-2017 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 GTHT12_RS02340 331466f6992c3971eb8f88c612f41d08 504 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 1 500 46.164 T 06-07-2017 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 GTHT12_RS02340 331466f6992c3971eb8f88c612f41d08 504 SUPERFAMILY SSF48557 1 494 8.63E-197 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 GTHT12_RS02340 331466f6992c3971eb8f88c612f41d08 504 Gene3D G3DSA:1.10.275.10 2 195 2.1E-79 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal GTHT12_RS02340 331466f6992c3971eb8f88c612f41d08 504 Pfam PF00221 Aromatic amino acid lyase 9 466 2.2E-199 T 06-07-2017 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 GTHT12_RS02340 331466f6992c3971eb8f88c612f41d08 504 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 137 153 - T 06-07-2017 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 GTHT12_RS02340 331466f6992c3971eb8f88c612f41d08 504 Gene3D G3DSA:1.20.200.10 196 496 6.3E-128 T 06-07-2017 GTHT12_RS18350 eae91fff7917f5332ff8759321ef6567 342 Gene3D G3DSA:2.70.70.10 199 334 1.6E-42 T 06-07-2017 GTHT12_RS18350 eae91fff7917f5332ff8759321ef6567 342 SUPERFAMILY SSF51261 198 332 6.8E-42 T 06-07-2017 IPR011055 Duplicated hybrid motif GTHT12_RS18350 eae91fff7917f5332ff8759321ef6567 342 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 77 187 9.1E-14 T 06-07-2017 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 GTHT12_RS18350 eae91fff7917f5332ff8759321ef6567 342 Pfam PF01551 Peptidase family M23 230 329 5.4E-27 T 06-07-2017 IPR016047 Peptidase M23 GTHT12_RS18350 eae91fff7917f5332ff8759321ef6567 342 Gene3D G3DSA:1.10.530.10 77 110 7.8E-5 T 06-07-2017 GTHT12_RS11065 79b0336abee8155c43b6808d7eb5a39f 487 SUPERFAMILY SSF58104 209 479 7.94E-52 T 06-07-2017 GTHT12_RS11065 79b0336abee8155c43b6808d7eb5a39f 487 SMART SM00283 220 481 4.5E-38 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 GTHT12_RS11065 79b0336abee8155c43b6808d7eb5a39f 487 Gene3D G3DSA:1.10.287.950 238 439 9.1E-49 T 06-07-2017 GTHT12_RS11065 79b0336abee8155c43b6808d7eb5a39f 487 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 287 470 1.6E-36 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 GTHT12_RS14225 dcd5405a15f143ef94b1d50bc985b09e 312 Gene3D G3DSA:3.90.110.10 150 310 1.5E-59 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 GTHT12_RS14225 dcd5405a15f143ef94b1d50bc985b09e 312 Hamap MF_00487 Malate dehydrogenase [mdh]. 6 312 47.2 T 06-07-2017 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 GTHT12_RS14225 dcd5405a15f143ef94b1d50bc985b09e 312 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 147 2.4E-42 T 06-07-2017 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 GTHT12_RS14225 dcd5405a15f143ef94b1d50bc985b09e 312 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 151 308 9.8E-29 T 06-07-2017 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 GTHT12_RS14225 dcd5405a15f143ef94b1d50bc985b09e 312 SUPERFAMILY SSF56327 151 309 6.63E-54 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 GTHT12_RS14225 dcd5405a15f143ef94b1d50bc985b09e 312 PRINTS PR00086 L-lactate dehydrogenase signature 175 188 1.1E-30 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 GTHT12_RS14225 dcd5405a15f143ef94b1d50bc985b09e 312 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 1.1E-30 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 GTHT12_RS14225 dcd5405a15f143ef94b1d50bc985b09e 312 PRINTS PR00086 L-lactate dehydrogenase signature 121 141 1.1E-30 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 GTHT12_RS14225 dcd5405a15f143ef94b1d50bc985b09e 312 PRINTS PR00086 L-lactate dehydrogenase signature 145 163 1.1E-30 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 GTHT12_RS14225 dcd5405a15f143ef94b1d50bc985b09e 312 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 1.1E-30 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 GTHT12_RS14225 dcd5405a15f143ef94b1d50bc985b09e 312 PIRSF PIRSF000102 2 312 1.9E-107 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 GTHT12_RS14225 dcd5405a15f143ef94b1d50bc985b09e 312 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 5 311 7.2E-165 T 06-07-2017 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 GTHT12_RS14225 dcd5405a15f143ef94b1d50bc985b09e 312 Gene3D G3DSA:3.40.50.720 1 147 3.2E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS14225 dcd5405a15f143ef94b1d50bc985b09e 312 SUPERFAMILY SSF51735 3 147 6.49E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS12225 a5a9d6eeb1156422e3bbd6c3000e61f0 150 SUPERFAMILY SSF46785 6 141 1.15E-39 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12225 a5a9d6eeb1156422e3bbd6c3000e61f0 150 Gene3D G3DSA:1.10.10.10 5 86 1.0E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12225 a5a9d6eeb1156422e3bbd6c3000e61f0 150 Pfam PF01475 Ferric uptake regulator family 15 136 2.0E-40 T 06-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 GTHT12_RS04660 ba01874e6bb699099c3144ff277bc267 400 Pfam PF00665 Integrase core domain 116 242 1.9E-26 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS04660 ba01874e6bb699099c3144ff277bc267 400 Pfam PF02796 Helix-turn-helix domain of resolvase 10 39 3.2E-6 T 06-07-2017 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 GTHT12_RS04660 ba01874e6bb699099c3144ff277bc267 400 Gene3D G3DSA:1.10.10.60 10 39 2.8E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS04660 ba01874e6bb699099c3144ff277bc267 400 SUPERFAMILY SSF53098 115 286 1.12E-21 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS04660 ba01874e6bb699099c3144ff277bc267 400 Gene3D G3DSA:3.30.420.10 117 279 1.2E-18 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS18750 ba01874e6bb699099c3144ff277bc267 400 Pfam PF00665 Integrase core domain 116 242 1.9E-26 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS18750 ba01874e6bb699099c3144ff277bc267 400 Pfam PF02796 Helix-turn-helix domain of resolvase 10 39 3.2E-6 T 06-07-2017 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 GTHT12_RS18750 ba01874e6bb699099c3144ff277bc267 400 Gene3D G3DSA:1.10.10.60 10 39 2.8E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS18750 ba01874e6bb699099c3144ff277bc267 400 SUPERFAMILY SSF53098 115 286 1.12E-21 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS18750 ba01874e6bb699099c3144ff277bc267 400 Gene3D G3DSA:3.30.420.10 117 279 1.2E-18 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS15300 5d1e83df5ecf0fce47f3cfe5e13275af 390 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 GTHT12_RS15300 5d1e83df5ecf0fce47f3cfe5e13275af 390 SUPERFAMILY SSF53383 8 389 2.5E-125 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS15300 5d1e83df5ecf0fce47f3cfe5e13275af 390 Gene3D G3DSA:3.40.640.10 51 258 2.5E-76 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS15300 5d1e83df5ecf0fce47f3cfe5e13275af 390 Gene3D G3DSA:3.90.1150.10 259 389 8.4E-49 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS15300 5d1e83df5ecf0fce47f3cfe5e13275af 390 Pfam PF00155 Aminotransferase class I and II 35 382 5.2E-73 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 GTHT12_RS15740 07db0b98718123771354c396aff9a66f 650 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 132 567 3.9E-95 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit GTHT12_RS15740 07db0b98718123771354c396aff9a66f 650 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 35 639 6.3E-230 T 06-07-2017 IPR011853 TRAP transporter, 4TM/12TM fusion protein GTHT12_RS02225 ae71c4f392ae57a792d3440b5fc61bd1 469 SUPERFAMILY SSF53738 267 375 2.35E-28 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS02225 ae71c4f392ae57a792d3440b5fc61bd1 469 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 165 263 8.3E-31 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS02225 ae71c4f392ae57a792d3440b5fc61bd1 469 Gene3D G3DSA:3.40.120.10 182 259 1.0E-33 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS02225 ae71c4f392ae57a792d3440b5fc61bd1 469 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 268 376 1.4E-17 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS02225 ae71c4f392ae57a792d3440b5fc61bd1 469 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 214 227 1.8E-21 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS02225 ae71c4f392ae57a792d3440b5fc61bd1 469 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 180 199 1.8E-21 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS02225 ae71c4f392ae57a792d3440b5fc61bd1 469 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 243 258 1.8E-21 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS02225 ae71c4f392ae57a792d3440b5fc61bd1 469 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 103 117 1.8E-21 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS02225 ae71c4f392ae57a792d3440b5fc61bd1 469 SUPERFAMILY SSF53738 163 264 1.37E-33 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS02225 ae71c4f392ae57a792d3440b5fc61bd1 469 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 104 113 - T 06-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS02225 ae71c4f392ae57a792d3440b5fc61bd1 469 SUPERFAMILY SSF53738 5 187 5.49E-37 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS02225 ae71c4f392ae57a792d3440b5fc61bd1 469 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 384 459 8.6E-13 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS02225 ae71c4f392ae57a792d3440b5fc61bd1 469 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 15 145 2.8E-31 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS02225 ae71c4f392ae57a792d3440b5fc61bd1 469 Gene3D G3DSA:3.30.310.50 381 462 1.2E-24 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS02225 ae71c4f392ae57a792d3440b5fc61bd1 469 Gene3D G3DSA:3.40.120.10 15 139 4.0E-31 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS02225 ae71c4f392ae57a792d3440b5fc61bd1 469 Gene3D G3DSA:3.40.120.10 260 378 3.1E-35 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS02225 ae71c4f392ae57a792d3440b5fc61bd1 469 SUPERFAMILY SSF55957 379 462 2.96E-21 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS13810 5a7c84c5064dd038bbd5a507e98808aa 309 SUPERFAMILY SSF53850 2 217 1.63E-81 T 06-07-2017 GTHT12_RS13810 5a7c84c5064dd038bbd5a507e98808aa 309 Gene3D G3DSA:3.30.160.40 220 302 6.2E-24 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13810 5a7c84c5064dd038bbd5a507e98808aa 309 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 226 291 6.0E-19 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13810 5a7c84c5064dd038bbd5a507e98808aa 309 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 294 4.1E-110 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13810 5a7c84c5064dd038bbd5a507e98808aa 309 Gene3D G3DSA:3.40.190.10 2 108 8.8E-43 T 06-07-2017 GTHT12_RS13810 5a7c84c5064dd038bbd5a507e98808aa 309 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 5.5E-49 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13810 5a7c84c5064dd038bbd5a507e98808aa 309 PRINTS PR00151 Porphobilinogen deaminase signature 122 139 5.5E-49 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13810 5a7c84c5064dd038bbd5a507e98808aa 309 PRINTS PR00151 Porphobilinogen deaminase signature 141 158 5.5E-49 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13810 5a7c84c5064dd038bbd5a507e98808aa 309 PRINTS PR00151 Porphobilinogen deaminase signature 229 246 5.5E-49 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13810 5a7c84c5064dd038bbd5a507e98808aa 309 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 5.5E-49 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13810 5a7c84c5064dd038bbd5a507e98808aa 309 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 294 38.93 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13810 5a7c84c5064dd038bbd5a507e98808aa 309 SUPERFAMILY SSF54782 219 306 3.01E-24 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13810 5a7c84c5064dd038bbd5a507e98808aa 309 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 212 6.9E-80 T 06-07-2017 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13810 5a7c84c5064dd038bbd5a507e98808aa 309 Gene3D G3DSA:3.40.190.10 109 198 4.0E-40 T 06-07-2017 GTHT12_RS13810 5a7c84c5064dd038bbd5a507e98808aa 309 PIRSF PIRSF001438 1 308 5.6E-122 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13810 5a7c84c5064dd038bbd5a507e98808aa 309 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 230 246 - T 06-07-2017 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS15115 a600c47a7089568c7d4467cc669ac8b9 139 Pfam PF13673 Acetyltransferase (GNAT) domain 32 122 6.5E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS15115 a600c47a7089568c7d4467cc669ac8b9 139 Gene3D G3DSA:3.40.630.30 10 128 2.3E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS15115 a600c47a7089568c7d4467cc669ac8b9 139 SUPERFAMILY SSF55729 11 126 1.26E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS09565 8d6306f44ba2cc064a9bab9db6d58c7d 489 Gene3D G3DSA:1.10.3650.10 357 434 1.7E-30 T 06-07-2017 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 GTHT12_RS09565 8d6306f44ba2cc064a9bab9db6d58c7d 489 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 484 6.9E-273 T 06-07-2017 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 GTHT12_RS09565 8d6306f44ba2cc064a9bab9db6d58c7d 489 Gene3D G3DSA:3.30.70.20 436 465 4.7E-76 T 06-07-2017 GTHT12_RS09565 8d6306f44ba2cc064a9bab9db6d58c7d 489 Gene3D G3DSA:3.30.70.20 234 356 4.7E-76 T 06-07-2017 GTHT12_RS09565 8d6306f44ba2cc064a9bab9db6d58c7d 489 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 356 435 3.7E-30 T 06-07-2017 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 GTHT12_RS09565 8d6306f44ba2cc064a9bab9db6d58c7d 489 Pfam PF13247 4Fe-4S dicluster domain 172 269 1.1E-36 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain GTHT12_RS09565 8d6306f44ba2cc064a9bab9db6d58c7d 489 SUPERFAMILY SSF54862 2 486 1.05E-162 T 06-07-2017 GTHT12_RS09565 8d6306f44ba2cc064a9bab9db6d58c7d 489 Gene3D G3DSA:3.30.70.20 161 193 1.7E-11 T 06-07-2017 GTHT12_RS09565 8d6306f44ba2cc064a9bab9db6d58c7d 489 Gene3D G3DSA:3.30.70.20 10 26 1.7E-11 T 06-07-2017 GTHT12_RS09565 8d6306f44ba2cc064a9bab9db6d58c7d 489 Gene3D G3DSA:3.30.70.20 194 233 7.5E-24 T 06-07-2017 GTHT12_RS08580 d45854a24bba01a419c45942a61113a9 399 Pfam PF13458 Periplasmic binding protein 44 355 3.4E-53 T 06-07-2017 IPR028081 Leucine-binding protein domain GTHT12_RS08580 d45854a24bba01a419c45942a61113a9 399 SUPERFAMILY SSF53822 43 394 6.73E-65 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS08580 d45854a24bba01a419c45942a61113a9 399 Gene3D G3DSA:3.40.50.2300 322 355 1.2E-31 T 06-07-2017 GTHT12_RS08580 d45854a24bba01a419c45942a61113a9 399 Gene3D G3DSA:3.40.50.2300 41 169 1.2E-31 T 06-07-2017 GTHT12_RS08580 d45854a24bba01a419c45942a61113a9 399 Gene3D G3DSA:3.40.50.2300 171 321 2.0E-29 T 06-07-2017 GTHT12_RS09000 ef0d17385e69aa5909c832049d3e3eb3 266 SMART SM00382 41 189 5.9E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS09000 ef0d17385e69aa5909c832049d3e3eb3 266 SUPERFAMILY SSF52540 29 263 2.51E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS09000 ef0d17385e69aa5909c832049d3e3eb3 266 Gene3D G3DSA:3.40.50.300 31 164 5.7E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS09000 ef0d17385e69aa5909c832049d3e3eb3 266 Pfam PF13401 AAA domain 40 169 3.4E-22 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS17010 ef0d17385e69aa5909c832049d3e3eb3 266 SMART SM00382 41 189 5.9E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS17010 ef0d17385e69aa5909c832049d3e3eb3 266 SUPERFAMILY SSF52540 29 263 2.51E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17010 ef0d17385e69aa5909c832049d3e3eb3 266 Gene3D G3DSA:3.40.50.300 31 164 5.7E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17010 ef0d17385e69aa5909c832049d3e3eb3 266 Pfam PF13401 AAA domain 40 169 3.4E-22 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS05270 ef0d17385e69aa5909c832049d3e3eb3 266 SMART SM00382 41 189 5.9E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS05270 ef0d17385e69aa5909c832049d3e3eb3 266 SUPERFAMILY SSF52540 29 263 2.51E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05270 ef0d17385e69aa5909c832049d3e3eb3 266 Gene3D G3DSA:3.40.50.300 31 164 5.7E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05270 ef0d17385e69aa5909c832049d3e3eb3 266 Pfam PF13401 AAA domain 40 169 3.4E-22 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS18405 ef0d17385e69aa5909c832049d3e3eb3 266 SMART SM00382 41 189 5.9E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS18405 ef0d17385e69aa5909c832049d3e3eb3 266 SUPERFAMILY SSF52540 29 263 2.51E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18405 ef0d17385e69aa5909c832049d3e3eb3 266 Gene3D G3DSA:3.40.50.300 31 164 5.7E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18405 ef0d17385e69aa5909c832049d3e3eb3 266 Pfam PF13401 AAA domain 40 169 3.4E-22 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS02115 ef0d17385e69aa5909c832049d3e3eb3 266 SMART SM00382 41 189 5.9E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS02115 ef0d17385e69aa5909c832049d3e3eb3 266 SUPERFAMILY SSF52540 29 263 2.51E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS02115 ef0d17385e69aa5909c832049d3e3eb3 266 Gene3D G3DSA:3.40.50.300 31 164 5.7E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS02115 ef0d17385e69aa5909c832049d3e3eb3 266 Pfam PF13401 AAA domain 40 169 3.4E-22 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS07185 ef0d17385e69aa5909c832049d3e3eb3 266 SMART SM00382 41 189 5.9E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS07185 ef0d17385e69aa5909c832049d3e3eb3 266 SUPERFAMILY SSF52540 29 263 2.51E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07185 ef0d17385e69aa5909c832049d3e3eb3 266 Gene3D G3DSA:3.40.50.300 31 164 5.7E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07185 ef0d17385e69aa5909c832049d3e3eb3 266 Pfam PF13401 AAA domain 40 169 3.4E-22 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS02750 ef0d17385e69aa5909c832049d3e3eb3 266 SMART SM00382 41 189 5.9E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS02750 ef0d17385e69aa5909c832049d3e3eb3 266 SUPERFAMILY SSF52540 29 263 2.51E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS02750 ef0d17385e69aa5909c832049d3e3eb3 266 Gene3D G3DSA:3.40.50.300 31 164 5.7E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS02750 ef0d17385e69aa5909c832049d3e3eb3 266 Pfam PF13401 AAA domain 40 169 3.4E-22 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS02015 ef0d17385e69aa5909c832049d3e3eb3 266 SMART SM00382 41 189 5.9E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS02015 ef0d17385e69aa5909c832049d3e3eb3 266 SUPERFAMILY SSF52540 29 263 2.51E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS02015 ef0d17385e69aa5909c832049d3e3eb3 266 Gene3D G3DSA:3.40.50.300 31 164 5.7E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS02015 ef0d17385e69aa5909c832049d3e3eb3 266 Pfam PF13401 AAA domain 40 169 3.4E-22 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS11300 ef0d17385e69aa5909c832049d3e3eb3 266 SMART SM00382 41 189 5.9E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS11300 ef0d17385e69aa5909c832049d3e3eb3 266 SUPERFAMILY SSF52540 29 263 2.51E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11300 ef0d17385e69aa5909c832049d3e3eb3 266 Gene3D G3DSA:3.40.50.300 31 164 5.7E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11300 ef0d17385e69aa5909c832049d3e3eb3 266 Pfam PF13401 AAA domain 40 169 3.4E-22 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS15090 ef0d17385e69aa5909c832049d3e3eb3 266 SMART SM00382 41 189 5.9E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS15090 ef0d17385e69aa5909c832049d3e3eb3 266 SUPERFAMILY SSF52540 29 263 2.51E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS15090 ef0d17385e69aa5909c832049d3e3eb3 266 Gene3D G3DSA:3.40.50.300 31 164 5.7E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS15090 ef0d17385e69aa5909c832049d3e3eb3 266 Pfam PF13401 AAA domain 40 169 3.4E-22 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS03090 ef0d17385e69aa5909c832049d3e3eb3 266 SMART SM00382 41 189 5.9E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS03090 ef0d17385e69aa5909c832049d3e3eb3 266 SUPERFAMILY SSF52540 29 263 2.51E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03090 ef0d17385e69aa5909c832049d3e3eb3 266 Gene3D G3DSA:3.40.50.300 31 164 5.7E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03090 ef0d17385e69aa5909c832049d3e3eb3 266 Pfam PF13401 AAA domain 40 169 3.4E-22 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS12325 10cca0082ff10c0a4121a004017d3bb2 354 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 208 230 - T 06-07-2017 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 GTHT12_RS12325 10cca0082ff10c0a4121a004017d3bb2 354 Pfam PF00742 Homoserine dehydrogenase 168 340 3.5E-56 T 06-07-2017 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 GTHT12_RS12325 10cca0082ff10c0a4121a004017d3bb2 354 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 9 153 3.0E-5 T 06-07-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 GTHT12_RS12325 10cca0082ff10c0a4121a004017d3bb2 354 SUPERFAMILY SSF55347 165 327 1.96E-50 T 06-07-2017 GTHT12_RS12325 10cca0082ff10c0a4121a004017d3bb2 354 Gene3D G3DSA:3.40.50.720 4 175 6.5E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS12325 10cca0082ff10c0a4121a004017d3bb2 354 SUPERFAMILY SSF51735 4 183 3.58E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS12325 10cca0082ff10c0a4121a004017d3bb2 354 Gene3D G3DSA:3.30.360.10 176 323 8.7E-52 T 06-07-2017 GTHT12_RS12325 10cca0082ff10c0a4121a004017d3bb2 354 PIRSF PIRSF036497 1 349 9.6E-105 T 06-07-2017 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 GTHT12_RS05355 7593aded83bbfeda799a5c3bc776e95f 671 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 1 502 1.8E-257 T 06-07-2017 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0015758|GO:0016021 GTHT12_RS05355 7593aded83bbfeda799a5c3bc776e95f 671 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 63 353 3.0E-89 T 06-07-2017 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 GTHT12_RS05355 7593aded83bbfeda799a5c3bc776e95f 671 Gene3D G3DSA:3.30.1360.60 427 501 5.5E-26 T 06-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 GTHT12_RS05355 7593aded83bbfeda799a5c3bc776e95f 671 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 402 486 6.9E-22 T 06-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 GTHT12_RS05355 7593aded83bbfeda799a5c3bc776e95f 671 Pfam PF00367 phosphotransferase system, EIIB 430 462 1.3E-13 T 06-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 GTHT12_RS05355 7593aded83bbfeda799a5c3bc776e95f 671 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 524 646 6.5E-53 T 06-07-2017 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 GTHT12_RS05355 7593aded83bbfeda799a5c3bc776e95f 671 SUPERFAMILY SSF51261 520 665 2.44E-55 T 06-07-2017 IPR011055 Duplicated hybrid motif GTHT12_RS05355 7593aded83bbfeda799a5c3bc776e95f 671 Gene3D G3DSA:2.70.70.10 519 665 9.1E-62 T 06-07-2017 GTHT12_RS05355 7593aded83bbfeda799a5c3bc776e95f 671 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 440 457 - T 06-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 GTHT12_RS05355 7593aded83bbfeda799a5c3bc776e95f 671 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 525 645 1.4E-48 T 06-07-2017 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 GTHT12_RS05355 7593aded83bbfeda799a5c3bc776e95f 671 SUPERFAMILY SSF55604 429 500 1.7E-20 T 06-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 GTHT12_RS05355 7593aded83bbfeda799a5c3bc776e95f 671 Pfam PF02378 Phosphotransferase system, EIIC 12 342 1.6E-96 T 06-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 GTHT12_RS05355 7593aded83bbfeda799a5c3bc776e95f 671 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 587 599 - T 06-07-2017 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 GTHT12_RS16260 57eb331c988e5dd3acd2098491fdcd31 140 Pfam PF02561 Flagellar protein FliS 10 113 8.0E-26 T 06-07-2017 IPR003713 Flagellar protein FliS GO:0044780 GTHT12_RS16260 57eb331c988e5dd3acd2098491fdcd31 140 TIGRFAM TIGR00208 fliS: flagellar protein FliS 12 116 3.2E-22 T 06-07-2017 IPR003713 Flagellar protein FliS GO:0044780 GTHT12_RS16260 57eb331c988e5dd3acd2098491fdcd31 140 SUPERFAMILY SSF101116 7 115 3.01E-27 T 06-07-2017 IPR003713 Flagellar protein FliS GO:0044780 GTHT12_RS16260 57eb331c988e5dd3acd2098491fdcd31 140 Gene3D G3DSA:1.20.120.340 8 116 4.5E-28 T 06-07-2017 IPR003713 Flagellar protein FliS GO:0044780 GTHT12_RS05170 f00e1ce958951aba1e6d9aab2f5ee5bc 244 SUPERFAMILY SSF102114 27 120 1.83E-14 T 06-07-2017 GTHT12_RS05170 f00e1ce958951aba1e6d9aab2f5ee5bc 244 Pfam PF13394 4Fe-4S single cluster domain 27 112 9.6E-12 T 06-07-2017 GTHT12_RS05170 f00e1ce958951aba1e6d9aab2f5ee5bc 244 Gene3D G3DSA:3.20.20.70 29 127 2.1E-15 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS05170 f00e1ce958951aba1e6d9aab2f5ee5bc 244 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 5 241 35.505 T 06-07-2017 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 GTHT12_RS05170 f00e1ce958951aba1e6d9aab2f5ee5bc 244 TIGRFAM TIGR03365 Bsubt_queE: 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 4 244 9.1E-116 T 06-07-2017 IPR017742 7-carboxy-7-deazaguanine synthase KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 GTHT12_RS05170 f00e1ce958951aba1e6d9aab2f5ee5bc 244 Pfam PF04055 Radical SAM superfamily 29 118 2.0E-12 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 GTHT12_RS05170 f00e1ce958951aba1e6d9aab2f5ee5bc 244 PIRSF PIRSF000370 3 244 3.3E-53 T 06-07-2017 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 GTHT12_RS12495 f6d000848896f69156f980ebbeacfdc3 573 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 526 1.2E-16 T 06-07-2017 IPR003395 RecF/RecN/SMC, N-terminal GTHT12_RS12495 f6d000848896f69156f980ebbeacfdc3 573 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 566 1.8E-194 T 06-07-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 GTHT12_RS12495 f6d000848896f69156f980ebbeacfdc3 573 Gene3D G3DSA:3.40.50.300 1 210 1.0E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12495 f6d000848896f69156f980ebbeacfdc3 573 PIRSF PIRSF003128 1 571 1.4E-188 T 06-07-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 GTHT12_RS12495 f6d000848896f69156f980ebbeacfdc3 573 SUPERFAMILY SSF52540 289 341 7.66E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12495 f6d000848896f69156f980ebbeacfdc3 573 SUPERFAMILY SSF52540 370 530 7.66E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12495 f6d000848896f69156f980ebbeacfdc3 573 SUPERFAMILY SSF52540 1 203 7.66E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12495 f6d000848896f69156f980ebbeacfdc3 573 Gene3D G3DSA:3.40.50.300 310 549 1.3E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS09165 539280c0b0e5ca4734d0eadba9ac4676 814 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 604 648 8.4E-8 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 GTHT12_RS09165 539280c0b0e5ca4734d0eadba9ac4676 814 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 706 753 1.8E-5 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 GTHT12_RS09165 539280c0b0e5ca4734d0eadba9ac4676 814 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 502 522 0.28 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 GTHT12_RS09165 539280c0b0e5ca4734d0eadba9ac4676 814 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 656 695 5.2E-6 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 GTHT12_RS09165 539280c0b0e5ca4734d0eadba9ac4676 814 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 547 597 2.6E-7 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 GTHT12_RS09165 539280c0b0e5ca4734d0eadba9ac4676 814 SUPERFAMILY SSF56719 28 483 4.58E-168 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 GTHT12_RS09165 539280c0b0e5ca4734d0eadba9ac4676 814 Hamap MF_00937 DNA topoisomerase 4 subunit A [parC]. 4 803 32.725 T 06-07-2017 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 GTHT12_RS09165 539280c0b0e5ca4734d0eadba9ac4676 814 Gene3D G3DSA:2.120.10.90 495 800 1.5E-80 T 06-07-2017 GTHT12_RS09165 539280c0b0e5ca4734d0eadba9ac4676 814 Gene3D G3DSA:3.30.1360.40 233 329 5.3E-36 T 06-07-2017 IPR024946 Arginine repressor C-terminal-like domain GTHT12_RS09165 539280c0b0e5ca4734d0eadba9ac4676 814 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 29 468 1.0E-149 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS09165 539280c0b0e5ca4734d0eadba9ac4676 814 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 6 744 0.0 T 06-07-2017 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 GTHT12_RS09165 539280c0b0e5ca4734d0eadba9ac4676 814 SMART SM00434 8 461 2.7E-262 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS09165 539280c0b0e5ca4734d0eadba9ac4676 814 Gene3D G3DSA:3.90.199.10 330 395 1.4E-114 T 06-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS09165 539280c0b0e5ca4734d0eadba9ac4676 814 Gene3D G3DSA:3.90.199.10 27 232 1.4E-114 T 06-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS09165 539280c0b0e5ca4734d0eadba9ac4676 814 SUPERFAMILY SSF101904 497 807 1.2E-89 T 06-07-2017 GTHT12_RS09165 539280c0b0e5ca4734d0eadba9ac4676 814 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 9 800 2.6E-271 T 06-07-2017 GTHT12_RS12275 0f2f28db34d8ea8b4a2653e88f9a6c46 65 Pfam PF14164 YqzH-like protein 1 64 2.6E-29 T 06-07-2017 IPR025546 YqzH-like protein GTHT12_RS09335 2fb0701594ebc28dd9ee786526d9d01d 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 84 264 5.5E-89 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 GTHT12_RS09335 2fb0701594ebc28dd9ee786526d9d01d 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 85 3.6E-40 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 GTHT12_RS09335 2fb0701594ebc28dd9ee786526d9d01d 264 ProSitePatterns PS00091 Thymidylate synthase active site. 126 154 - T 06-07-2017 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 GTHT12_RS09335 2fb0701594ebc28dd9ee786526d9d01d 264 Pfam PF00303 Thymidylate synthase 2 264 2.8E-122 T 06-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 GTHT12_RS09335 2fb0701594ebc28dd9ee786526d9d01d 264 Hamap MF_00008 Thymidylate synthase [thyA]. 1 264 39.993 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 GTHT12_RS09335 2fb0701594ebc28dd9ee786526d9d01d 264 SUPERFAMILY SSF55831 3 264 4.58E-129 T 06-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 GTHT12_RS09335 2fb0701594ebc28dd9ee786526d9d01d 264 PRINTS PR00108 Thymidylate synthase family signature 42 63 6.5E-45 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 GTHT12_RS09335 2fb0701594ebc28dd9ee786526d9d01d 264 PRINTS PR00108 Thymidylate synthase family signature 115 134 6.5E-45 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 GTHT12_RS09335 2fb0701594ebc28dd9ee786526d9d01d 264 PRINTS PR00108 Thymidylate synthase family signature 197 214 6.5E-45 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 GTHT12_RS09335 2fb0701594ebc28dd9ee786526d9d01d 264 PRINTS PR00108 Thymidylate synthase family signature 159 185 6.5E-45 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 GTHT12_RS09335 2fb0701594ebc28dd9ee786526d9d01d 264 PRINTS PR00108 Thymidylate synthase family signature 141 156 6.5E-45 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 GTHT12_RS09335 2fb0701594ebc28dd9ee786526d9d01d 264 Gene3D G3DSA:3.30.572.10 2 264 1.8E-132 T 06-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 GTHT12_RS17610 80bafedaa7e3a19a9f4ded80b7a9c218 287 Gene3D G3DSA:3.20.20.70 1 285 4.1E-114 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS17610 80bafedaa7e3a19a9f4ded80b7a9c218 287 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 134 145 - T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 GTHT12_RS17610 80bafedaa7e3a19a9f4ded80b7a9c218 287 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 284 3.5E-107 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 GTHT12_RS17610 80bafedaa7e3a19a9f4ded80b7a9c218 287 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 285 9.8E-133 T 06-07-2017 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 GTHT12_RS17610 80bafedaa7e3a19a9f4ded80b7a9c218 287 PIRSF PIRSF001359 1 285 4.3E-128 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 GTHT12_RS17610 80bafedaa7e3a19a9f4ded80b7a9c218 287 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 285 8.6E-114 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 GTHT12_RS17610 80bafedaa7e3a19a9f4ded80b7a9c218 287 SUPERFAMILY SSF51569 1 285 3.66E-107 T 06-07-2017 GTHT12_RS17610 80bafedaa7e3a19a9f4ded80b7a9c218 287 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 GTHT12_RS09425 4f2f2859589d8f2f06d857b2aba552bd 257 Gene3D G3DSA:3.30.950.10 112 231 1.7E-34 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS09425 4f2f2859589d8f2f06d857b2aba552bd 257 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 GTHT12_RS09425 4f2f2859589d8f2f06d857b2aba552bd 257 SUPERFAMILY SSF53790 2 250 1.11E-66 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS09425 4f2f2859589d8f2f06d857b2aba552bd 257 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 209 9.4E-46 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS09425 4f2f2859589d8f2f06d857b2aba552bd 257 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 253 1.1E-102 T 06-07-2017 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 GTHT12_RS09425 4f2f2859589d8f2f06d857b2aba552bd 257 Gene3D G3DSA:3.40.1010.10 2 111 2.1E-31 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS15465 cbe2476ab817cc64db60323a97063ad0 432 SUPERFAMILY SSF55021 349 422 1.1E-13 T 06-07-2017 GTHT12_RS15465 cbe2476ab817cc64db60323a97063ad0 432 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 184 206 - T 06-07-2017 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 GTHT12_RS15465 cbe2476ab817cc64db60323a97063ad0 432 SUPERFAMILY SSF55347 138 303 2.68E-54 T 06-07-2017 GTHT12_RS15465 cbe2476ab817cc64db60323a97063ad0 432 PIRSF PIRSF000098 2 430 2.1E-172 T 06-07-2017 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 GTHT12_RS15465 cbe2476ab817cc64db60323a97063ad0 432 Gene3D G3DSA:3.30.360.10 150 300 1.4E-59 T 06-07-2017 GTHT12_RS15465 cbe2476ab817cc64db60323a97063ad0 432 Pfam PF00742 Homoserine dehydrogenase 138 316 2.3E-67 T 06-07-2017 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 GTHT12_RS15465 cbe2476ab817cc64db60323a97063ad0 432 Pfam PF01842 ACT domain 350 416 1.3E-12 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 GTHT12_RS15465 cbe2476ab817cc64db60323a97063ad0 432 Gene3D G3DSA:3.40.50.720 2 149 2.3E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS15465 cbe2476ab817cc64db60323a97063ad0 432 Gene3D G3DSA:3.30.70.260 349 422 7.1E-14 T 06-07-2017 GTHT12_RS15465 cbe2476ab817cc64db60323a97063ad0 432 SUPERFAMILY SSF51735 2 159 1.31E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS15465 cbe2476ab817cc64db60323a97063ad0 432 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 11 130 1.3E-24 T 06-07-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 GTHT12_RS15465 cbe2476ab817cc64db60323a97063ad0 432 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 349 421 0.003 T 06-07-2017 GTHT12_RS13095 cce373657056b7bf73d515170f5d44ac 223 Pfam PF01791 DeoC/LacD family aldolase 7 213 9.3E-21 T 06-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 GTHT12_RS13095 cce373657056b7bf73d515170f5d44ac 223 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 5 214 2.1E-94 T 06-07-2017 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-71336 GTHT12_RS13095 cce373657056b7bf73d515170f5d44ac 223 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 3 218 38.781 T 06-07-2017 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 GTHT12_RS13095 cce373657056b7bf73d515170f5d44ac 223 PIRSF PIRSF001357 2 222 1.9E-79 T 06-07-2017 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-71336 GTHT12_RS13095 cce373657056b7bf73d515170f5d44ac 223 SMART SM01133 4 216 2.7E-113 T 06-07-2017 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-71336 GTHT12_RS13095 cce373657056b7bf73d515170f5d44ac 223 Gene3D G3DSA:3.20.20.70 4 217 8.7E-99 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS13095 cce373657056b7bf73d515170f5d44ac 223 SUPERFAMILY SSF51569 3 217 8.9E-89 T 06-07-2017 GTHT12_RS17640 8fac0f3d57d253d379307a72d2c56898 210 SUPERFAMILY SSF48498 92 205 2.94E-10 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal GTHT12_RS17640 8fac0f3d57d253d379307a72d2c56898 210 SUPERFAMILY SSF46689 18 92 3.49E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS17640 8fac0f3d57d253d379307a72d2c56898 210 Gene3D G3DSA:1.10.10.60 18 69 9.6E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS17640 8fac0f3d57d253d379307a72d2c56898 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 1.5E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS17640 8fac0f3d57d253d379307a72d2c56898 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 1.5E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS17640 8fac0f3d57d253d379307a72d2c56898 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 66 2.2E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS17640 8fac0f3d57d253d379307a72d2c56898 210 Gene3D G3DSA:1.10.357.10 70 207 2.4E-21 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 GTHT12_RS06155 03eb5239acd9f3870c374bffdc3f7355 220 Pfam PF01842 ACT domain 151 210 5.1E-11 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 GTHT12_RS06155 03eb5239acd9f3870c374bffdc3f7355 220 Gene3D G3DSA:3.30.1330.90 13 134 1.7E-27 T 06-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 GTHT12_RS06155 03eb5239acd9f3870c374bffdc3f7355 220 SUPERFAMILY SSF143548 19 137 2.75E-31 T 06-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 GTHT12_RS06155 03eb5239acd9f3870c374bffdc3f7355 220 PIRSF PIRSF036692 1 220 4.0E-100 T 06-07-2017 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 GTHT12_RS06155 03eb5239acd9f3870c374bffdc3f7355 220 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 1 206 5.9E-88 T 06-07-2017 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 GTHT12_RS06155 03eb5239acd9f3870c374bffdc3f7355 220 Pfam PF03315 Serine dehydratase beta chain 5 72 1.6E-11 T 06-07-2017 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 GTHT12_RS06155 03eb5239acd9f3870c374bffdc3f7355 220 SUPERFAMILY SSF55021 136 217 3.28E-18 T 06-07-2017 GTHT12_RS06155 03eb5239acd9f3870c374bffdc3f7355 220 Gene3D G3DSA:3.30.70.260 135 216 3.2E-21 T 06-07-2017 GTHT12_RS15810 113c41ec557c325e16452619781d5877 309 SMART SM01130 9 298 5.8E-133 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 GTHT12_RS15810 113c41ec557c325e16452619781d5877 309 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 13 295 8.9E-94 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS15810 113c41ec557c325e16452619781d5877 309 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 141 172 - T 06-07-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS15810 113c41ec557c325e16452619781d5877 309 Pfam PF00701 Dihydrodipicolinate synthetase family 10 294 8.9E-89 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 GTHT12_RS15810 113c41ec557c325e16452619781d5877 309 TIGRFAM TIGR02313 HpaI-NOT-DapA: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 10 301 9.5E-149 T 06-07-2017 IPR012691 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase variant GO:0005737|GO:0008840|GO:0019877 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS15810 113c41ec557c325e16452619781d5877 309 SUPERFAMILY SSF51569 9 299 4.5E-100 T 06-07-2017 GTHT12_RS15810 113c41ec557c325e16452619781d5877 309 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 9 296 56.728 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS15810 113c41ec557c325e16452619781d5877 309 PIRSF PIRSF001365 7 308 3.4E-92 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 GTHT12_RS15810 113c41ec557c325e16452619781d5877 309 Gene3D G3DSA:3.20.20.70 8 300 4.7E-109 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS15810 113c41ec557c325e16452619781d5877 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 136 153 3.3E-26 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 GTHT12_RS15810 113c41ec557c325e16452619781d5877 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 43 64 3.3E-26 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 GTHT12_RS15810 113c41ec557c325e16452619781d5877 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 79 97 3.3E-26 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 GTHT12_RS15810 113c41ec557c325e16452619781d5877 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 111 127 3.3E-26 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 GTHT12_RS13205 c5d2e00cd69ae593c9bb186ba3446f22 118 Pfam PF02410 Ribosomal silencing factor during starvation 10 104 5.5E-28 T 06-07-2017 GTHT12_RS13205 c5d2e00cd69ae593c9bb186ba3446f22 118 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 2 105 25.985 T 06-07-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS GTHT12_RS13205 c5d2e00cd69ae593c9bb186ba3446f22 118 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 7 104 6.4E-38 T 06-07-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS GTHT12_RS13205 c5d2e00cd69ae593c9bb186ba3446f22 118 Gene3D G3DSA:3.30.460.10 3 108 7.6E-39 T 06-07-2017 GTHT12_RS13205 c5d2e00cd69ae593c9bb186ba3446f22 118 SUPERFAMILY SSF81301 4 113 2.94E-41 T 06-07-2017 GTHT12_RS15885 fbc65a24e6deaa421a44b73dcf8b6b26 511 Gene3D G3DSA:3.40.720.10 4 77 4.2E-97 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 GTHT12_RS15885 fbc65a24e6deaa421a44b73dcf8b6b26 511 Gene3D G3DSA:3.40.720.10 315 509 4.2E-97 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 GTHT12_RS15885 fbc65a24e6deaa421a44b73dcf8b6b26 511 PIRSF PIRSF001492 1 511 3.4E-207 T 06-07-2017 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS15885 fbc65a24e6deaa421a44b73dcf8b6b26 511 Gene3D G3DSA:3.40.1450.10 78 311 3.0E-99 T 06-07-2017 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS15885 fbc65a24e6deaa421a44b73dcf8b6b26 511 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 4 510 50.501 T 06-07-2017 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS15885 fbc65a24e6deaa421a44b73dcf8b6b26 511 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 82 299 9.8E-85 T 06-07-2017 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS15885 fbc65a24e6deaa421a44b73dcf8b6b26 511 SUPERFAMILY SSF53649 311 508 3.27E-79 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 GTHT12_RS15885 fbc65a24e6deaa421a44b73dcf8b6b26 511 SUPERFAMILY SSF53649 4 77 3.27E-79 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 GTHT12_RS15885 fbc65a24e6deaa421a44b73dcf8b6b26 511 SUPERFAMILY SSF64158 77 310 8.24E-94 T 06-07-2017 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS15885 fbc65a24e6deaa421a44b73dcf8b6b26 511 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 5 509 1.1E-210 T 06-07-2017 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS15885 fbc65a24e6deaa421a44b73dcf8b6b26 511 Pfam PF01676 Metalloenzyme superfamily 5 498 1.4E-79 T 06-07-2017 IPR006124 Metalloenzyme GO:0003824|GO:0046872 GTHT12_RS11640 e18d77521cd51b5c3a1f7d9732cb5395 219 SUPERFAMILY SSF51366 3 209 1.38E-50 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 GTHT12_RS11640 e18d77521cd51b5c3a1f7d9732cb5395 219 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 5 206 1.6E-47 T 06-07-2017 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 GTHT12_RS11640 e18d77521cd51b5c3a1f7d9732cb5395 219 Gene3D G3DSA:3.20.20.70 2 210 1.3E-57 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS11640 e18d77521cd51b5c3a1f7d9732cb5395 219 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 2 211 36.778 T 06-07-2017 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 GTHT12_RS07880 0bd795688d467dd0bc486249fbbb96ba 482 Pfam PF02913 FAD linked oxidases, C-terminal domain 223 464 7.1E-61 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 GTHT12_RS07880 0bd795688d467dd0bc486249fbbb96ba 482 SUPERFAMILY SSF55103 226 469 1.13E-64 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 GTHT12_RS07880 0bd795688d467dd0bc486249fbbb96ba 482 Pfam PF01565 FAD binding domain 47 185 1.4E-42 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 GTHT12_RS07880 0bd795688d467dd0bc486249fbbb96ba 482 Gene3D G3DSA:3.30.465.10 103 223 5.1E-37 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 GTHT12_RS07880 0bd795688d467dd0bc486249fbbb96ba 482 SUPERFAMILY SSF56176 10 223 9.35E-75 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 GTHT12_RS07880 0bd795688d467dd0bc486249fbbb96ba 482 Gene3D G3DSA:3.30.43.10 6 101 2.7E-33 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 GTHT12_RS07710 7ae0eb890f31a34ab92ef4d83fe970fd 249 SMART SM00346 2 89 3.0E-17 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 GTHT12_RS07710 7ae0eb890f31a34ab92ef4d83fe970fd 249 Gene3D G3DSA:3.30.450.40 72 246 6.2E-56 T 06-07-2017 IPR029016 GAF domain-like GTHT12_RS07710 7ae0eb890f31a34ab92ef4d83fe970fd 249 SUPERFAMILY SSF55781 57 245 4.51E-50 T 06-07-2017 IPR029016 GAF domain-like GTHT12_RS07710 7ae0eb890f31a34ab92ef4d83fe970fd 249 SUPERFAMILY SSF46785 4 73 1.04E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS07710 7ae0eb890f31a34ab92ef4d83fe970fd 249 Pfam PF09339 IclR helix-turn-helix domain 6 53 1.0E-9 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 GTHT12_RS07710 7ae0eb890f31a34ab92ef4d83fe970fd 249 Gene3D G3DSA:1.10.10.10 2 61 5.9E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS07710 7ae0eb890f31a34ab92ef4d83fe970fd 249 Pfam PF01614 Bacterial transcriptional regulator 117 241 1.2E-31 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal GTHT12_RS13180 5ff23bbd71bdb975ce5339b8069156d1 748 Pfam PF00753 Metallo-beta-lactamase superfamily 493 700 5.8E-17 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS13180 5ff23bbd71bdb975ce5339b8069156d1 748 Pfam PF13567 Domain of unknown function (DUF4131) 26 166 5.1E-16 T 06-07-2017 IPR025405 Domain of unknown function DUF4131 GTHT12_RS13180 5ff23bbd71bdb975ce5339b8069156d1 748 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 98 730 4.0E-121 T 06-07-2017 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 GTHT12_RS13180 5ff23bbd71bdb975ce5339b8069156d1 748 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 229 395 4.2E-33 T 06-07-2017 IPR004477 ComEC/Rec2-related protein GTHT12_RS13180 5ff23bbd71bdb975ce5339b8069156d1 748 Gene3D G3DSA:3.60.15.10 486 723 9.4E-36 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS13180 5ff23bbd71bdb975ce5339b8069156d1 748 Pfam PF03772 Competence protein 207 460 1.5E-60 T 06-07-2017 IPR004477 ComEC/Rec2-related protein GTHT12_RS13180 5ff23bbd71bdb975ce5339b8069156d1 748 SUPERFAMILY SSF56281 487 742 1.05E-53 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS13180 5ff23bbd71bdb975ce5339b8069156d1 748 SMART SM00849 496 701 1.0E-12 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS08245 5501e046c42da203bca2821a82323415 299 SUPERFAMILY SSF51569 3 295 4.25E-75 T 06-07-2017 GTHT12_RS08245 5501e046c42da203bca2821a82323415 299 Gene3D G3DSA:3.20.20.70 6 292 2.7E-89 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS08245 5501e046c42da203bca2821a82323415 299 Pfam PF00682 HMGL-like 7 279 5.6E-52 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 GTHT12_RS01590 5a89b4be4515697f6387f77f9716a3b8 162 SMART SM01001 3 154 5.3E-108 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 GTHT12_RS01590 5a89b4be4515697f6387f77f9716a3b8 162 Pfam PF00731 AIR carboxylase 5 151 8.2E-67 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 GTHT12_RS01590 5a89b4be4515697f6387f77f9716a3b8 162 Gene3D G3DSA:3.40.50.7700 2 161 3.8E-78 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 GTHT12_RS01590 5a89b4be4515697f6387f77f9716a3b8 162 PIRSF PIRSF001338 1 162 2.0E-70 T 06-07-2017 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 GTHT12_RS01590 5a89b4be4515697f6387f77f9716a3b8 162 SUPERFAMILY SSF52255 4 161 2.09E-69 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 GTHT12_RS01590 5a89b4be4515697f6387f77f9716a3b8 162 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 158 33.606 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 GTHT12_RS01590 5a89b4be4515697f6387f77f9716a3b8 162 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 161 2.6E-68 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 GTHT12_RS15730 74b88a6fc41c33ad47a0b83bb0676a94 155 SMART SM00903 10 152 8.5E-54 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 GTHT12_RS15730 74b88a6fc41c33ad47a0b83bb0676a94 155 Pfam PF01613 Flavin reductase like domain 10 153 6.9E-37 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 GTHT12_RS15730 74b88a6fc41c33ad47a0b83bb0676a94 155 SUPERFAMILY SSF50475 1 153 3.09E-46 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 GTHT12_RS15730 74b88a6fc41c33ad47a0b83bb0676a94 155 Gene3D G3DSA:2.30.110.10 2 151 8.0E-51 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 GTHT12_RS15755 74b88a6fc41c33ad47a0b83bb0676a94 155 SMART SM00903 10 152 8.5E-54 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 GTHT12_RS15755 74b88a6fc41c33ad47a0b83bb0676a94 155 Pfam PF01613 Flavin reductase like domain 10 153 6.9E-37 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 GTHT12_RS15755 74b88a6fc41c33ad47a0b83bb0676a94 155 SUPERFAMILY SSF50475 1 153 3.09E-46 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 GTHT12_RS15755 74b88a6fc41c33ad47a0b83bb0676a94 155 Gene3D G3DSA:2.30.110.10 2 151 8.0E-51 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 GTHT12_RS18855 cd54e9f53204eea1ed6b2bd9433631d6 283 Pfam PF00753 Metallo-beta-lactamase superfamily 39 234 8.6E-18 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS18855 cd54e9f53204eea1ed6b2bd9433631d6 283 Gene3D G3DSA:3.60.15.10 24 280 1.2E-41 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS18855 cd54e9f53204eea1ed6b2bd9433631d6 283 SUPERFAMILY SSF56281 30 277 6.16E-57 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS18855 cd54e9f53204eea1ed6b2bd9433631d6 283 SMART SM00849 41 235 8.8E-11 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS06745 582744932800b458e0d4970640bbfaa3 288 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 199 263 2.3E-22 T 06-07-2017 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal GTHT12_RS06745 582744932800b458e0d4970640bbfaa3 288 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 14 283 3.7E-98 T 06-07-2017 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate GTHT12_RS06745 582744932800b458e0d4970640bbfaa3 288 SUPERFAMILY SSF52518 12 284 5.11E-79 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS06745 582744932800b458e0d4970640bbfaa3 288 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 48 195 7.2E-34 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 GTHT12_RS06745 582744932800b458e0d4970640bbfaa3 288 Gene3D G3DSA:3.40.50.970 13 228 1.9E-80 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS07820 c542dc6c0625e8cef4681ad6cefbecda 367 Pfam PF00512 His Kinase A (phospho-acceptor) domain 157 216 9.4E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS07820 c542dc6c0625e8cef4681ad6cefbecda 367 Pfam PF09385 Histidine kinase N terminal 6 133 3.9E-43 T 06-07-2017 IPR018984 Histidine kinase, N-terminal GTHT12_RS07820 c542dc6c0625e8cef4681ad6cefbecda 367 PRINTS PR00344 Bacterial sensor protein C-terminal signature 319 329 1.7E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS07820 c542dc6c0625e8cef4681ad6cefbecda 367 PRINTS PR00344 Bacterial sensor protein C-terminal signature 330 348 1.7E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS07820 c542dc6c0625e8cef4681ad6cefbecda 367 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 366 1.7E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS07820 c542dc6c0625e8cef4681ad6cefbecda 367 PRINTS PR00344 Bacterial sensor protein C-terminal signature 301 315 1.7E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS07820 c542dc6c0625e8cef4681ad6cefbecda 367 SMART SM00388 156 218 5.9E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS07820 c542dc6c0625e8cef4681ad6cefbecda 367 SUPERFAMILY SSF55874 208 367 1.57E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS07820 c542dc6c0625e8cef4681ad6cefbecda 367 Gene3D G3DSA:1.10.287.130 151 214 1.9E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS07820 c542dc6c0625e8cef4681ad6cefbecda 367 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 263 366 1.7E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS07820 c542dc6c0625e8cef4681ad6cefbecda 367 Gene3D G3DSA:3.30.565.10 220 367 2.1E-39 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS07820 c542dc6c0625e8cef4681ad6cefbecda 367 SUPERFAMILY SSF47384 148 216 8.44E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS07820 c542dc6c0625e8cef4681ad6cefbecda 367 SMART SM00387 261 367 1.8E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS00555 4c557268d0405036d775e831ee8fb77c 467 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 465 9.1E-193 T 06-07-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 GTHT12_RS00555 4c557268d0405036d775e831ee8fb77c 467 SUPERFAMILY SSF52374 5 315 1.26E-108 T 06-07-2017 GTHT12_RS00555 4c557268d0405036d775e831ee8fb77c 467 SMART SM00840 354 417 2.0E-17 T 06-07-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 GTHT12_RS00555 4c557268d0405036d775e831ee8fb77c 467 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 4 466 40.378 T 06-07-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 GTHT12_RS00555 4c557268d0405036d775e831ee8fb77c 467 Gene3D G3DSA:3.40.50.620 21 306 2.2E-113 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS00555 4c557268d0405036d775e831ee8fb77c 467 SUPERFAMILY SSF47323 317 465 3.27E-37 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS00555 4c557268d0405036d775e831ee8fb77c 467 Pfam PF09190 DALR domain 355 414 4.5E-18 T 06-07-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 GTHT12_RS00555 4c557268d0405036d775e831ee8fb77c 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 27 38 5.4E-30 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 GTHT12_RS00555 4c557268d0405036d775e831ee8fb77c 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 63 72 5.4E-30 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 GTHT12_RS00555 4c557268d0405036d775e831ee8fb77c 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 192 210 5.4E-30 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 GTHT12_RS00555 4c557268d0405036d775e831ee8fb77c 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 223 244 5.4E-30 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 GTHT12_RS00555 4c557268d0405036d775e831ee8fb77c 467 Gene3D G3DSA:1.20.120.640 307 408 1.9E-25 T 06-07-2017 GTHT12_RS00555 4c557268d0405036d775e831ee8fb77c 467 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 314 4.6E-140 T 06-07-2017 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 GTHT12_RS10610 5b3d2786fa685b0eaa1c2f44cb5571af 529 Gene3D G3DSA:3.30.300.30 422 526 9.6E-34 T 06-07-2017 GTHT12_RS10610 5b3d2786fa685b0eaa1c2f44cb5571af 529 Gene3D G3DSA:2.30.38.10 342 415 2.4E-21 T 06-07-2017 GTHT12_RS10610 5b3d2786fa685b0eaa1c2f44cb5571af 529 SUPERFAMILY SSF56801 16 525 2.49E-151 T 06-07-2017 GTHT12_RS10610 5b3d2786fa685b0eaa1c2f44cb5571af 529 Pfam PF00501 AMP-binding enzyme 26 425 5.2E-91 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GTHT12_RS10610 5b3d2786fa685b0eaa1c2f44cb5571af 529 Pfam PF13193 AMP-binding enzyme C-terminal domain 434 512 3.8E-22 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain GTHT12_RS10610 5b3d2786fa685b0eaa1c2f44cb5571af 529 TIGRFAM TIGR02262 benz_CoA_lig: benzoate-CoA ligase family 10 520 6.2E-186 T 06-07-2017 IPR011957 Benzoate-CoA ligase family GO:0005524|GO:0016405 GTHT12_RS10610 5b3d2786fa685b0eaa1c2f44cb5571af 529 Gene3D G3DSA:3.40.50.980 26 181 7.4E-37 T 06-07-2017 GTHT12_RS10610 5b3d2786fa685b0eaa1c2f44cb5571af 529 Gene3D G3DSA:3.40.50.980 182 340 5.4E-36 T 06-07-2017 GTHT12_RS12630 a73fe96a62eb9fb1f02ec406d35ed256 294 Gene3D G3DSA:3.40.1090.10 8 194 3.4E-19 T 06-07-2017 GTHT12_RS12630 a73fe96a62eb9fb1f02ec406d35ed256 294 Pfam PF01734 Patatin-like phospholipase 5 195 3.1E-34 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 GTHT12_RS12630 a73fe96a62eb9fb1f02ec406d35ed256 294 SUPERFAMILY SSF52151 5 292 1.28E-46 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 GTHT12_RS00435 fa35f611441dbe84977e3decc34e9678 333 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 4 319 1.3E-132 T 06-07-2017 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 GTHT12_RS00435 fa35f611441dbe84977e3decc34e9678 333 Gene3D G3DSA:3.20.20.70 8 246 1.0E-87 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS00435 fa35f611441dbe84977e3decc34e9678 333 Pfam PF01207 Dihydrouridine synthase (Dus) 14 318 2.0E-109 T 06-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 GTHT12_RS00435 fa35f611441dbe84977e3decc34e9678 333 PIRSF PIRSF006621 1 331 2.0E-108 T 06-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 GTHT12_RS00435 fa35f611441dbe84977e3decc34e9678 333 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 96 114 - T 06-07-2017 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 GTHT12_RS00435 fa35f611441dbe84977e3decc34e9678 333 SUPERFAMILY SSF51395 11 315 8.97E-92 T 06-07-2017 GTHT12_RS00435 fa35f611441dbe84977e3decc34e9678 333 Gene3D G3DSA:1.10.1200.80 253 325 1.0E-29 T 06-07-2017 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 GTHT12_RS16255 df6a2f43a314366df0395023f4ebb846 604 Gene3D G3DSA:1.20.1330.10 455 559 4.1E-69 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 GTHT12_RS16255 df6a2f43a314366df0395023f4ebb846 604 Gene3D G3DSA:1.20.1330.10 52 138 4.1E-69 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 GTHT12_RS16255 df6a2f43a314366df0395023f4ebb846 604 Pfam PF00700 Bacterial flagellin C-terminal helical region 517 602 2.0E-28 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 GTHT12_RS16255 df6a2f43a314366df0395023f4ebb846 604 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 139 7.4E-47 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 GTHT12_RS16255 df6a2f43a314366df0395023f4ebb846 604 SUPERFAMILY SSF64518 1 349 1.29E-94 T 06-07-2017 GTHT12_RS16255 df6a2f43a314366df0395023f4ebb846 604 SUPERFAMILY SSF64518 461 603 1.29E-94 T 06-07-2017 GTHT12_RS16255 df6a2f43a314366df0395023f4ebb846 604 PRINTS PR00207 Flagellin signature 35 52 2.1E-26 T 06-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 GTHT12_RS16255 df6a2f43a314366df0395023f4ebb846 604 PRINTS PR00207 Flagellin signature 109 132 2.1E-26 T 06-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 GTHT12_RS16255 df6a2f43a314366df0395023f4ebb846 604 PRINTS PR00207 Flagellin signature 74 93 2.1E-26 T 06-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 GTHT12_RS16505 c1b5f1e8b37cdc959b4d32c84f0b9b0d 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 453 3.6E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS16505 c1b5f1e8b37cdc959b4d32c84f0b9b0d 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 475 3.6E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS16505 c1b5f1e8b37cdc959b4d32c84f0b9b0d 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 411 3.6E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS16505 c1b5f1e8b37cdc959b4d32c84f0b9b0d 481 Gene3D G3DSA:3.30.565.10 319 476 5.1E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS16505 c1b5f1e8b37cdc959b4d32c84f0b9b0d 481 SMART SM00304 198 251 9.0E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS16505 c1b5f1e8b37cdc959b4d32c84f0b9b0d 481 SUPERFAMILY SSF158472 199 250 1.31E-7 T 06-07-2017 GTHT12_RS16505 c1b5f1e8b37cdc959b4d32c84f0b9b0d 481 Pfam PF00672 HAMP domain 181 247 2.8E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS16505 c1b5f1e8b37cdc959b4d32c84f0b9b0d 481 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 365 476 8.4E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS16505 c1b5f1e8b37cdc959b4d32c84f0b9b0d 481 SUPERFAMILY SSF55874 321 475 5.37E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS16505 c1b5f1e8b37cdc959b4d32c84f0b9b0d 481 Pfam PF06580 Histidine kinase 266 344 2.0E-23 T 06-07-2017 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 GTHT12_RS16505 c1b5f1e8b37cdc959b4d32c84f0b9b0d 481 SMART SM00387 360 478 2.7E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS10975 f39b2a15b82ded58189ce0e0dd1d093e 108 SUPERFAMILY SSF46689 11 105 3.76E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS10975 f39b2a15b82ded58189ce0e0dd1d093e 108 Pfam PF01527 Transposase 9 96 4.9E-13 T 06-07-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 GTHT12_RS10975 f39b2a15b82ded58189ce0e0dd1d093e 108 Gene3D G3DSA:1.10.10.60 15 102 8.9E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS07950 f39b2a15b82ded58189ce0e0dd1d093e 108 SUPERFAMILY SSF46689 11 105 3.76E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS07950 f39b2a15b82ded58189ce0e0dd1d093e 108 Pfam PF01527 Transposase 9 96 4.9E-13 T 06-07-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 GTHT12_RS07950 f39b2a15b82ded58189ce0e0dd1d093e 108 Gene3D G3DSA:1.10.10.60 15 102 8.9E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS03130 5f12e6fa21886126a9ce09e7f1e89ce0 317 Gene3D G3DSA:3.90.110.10 150 312 1.1E-61 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 GTHT12_RS03130 5f12e6fa21886126a9ce09e7f1e89ce0 317 PRINTS PR00086 L-lactate dehydrogenase signature 144 162 9.6E-53 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 GTHT12_RS03130 5f12e6fa21886126a9ce09e7f1e89ce0 317 PRINTS PR00086 L-lactate dehydrogenase signature 120 140 9.6E-53 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 GTHT12_RS03130 5f12e6fa21886126a9ce09e7f1e89ce0 317 PRINTS PR00086 L-lactate dehydrogenase signature 174 187 9.6E-53 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 GTHT12_RS03130 5f12e6fa21886126a9ce09e7f1e89ce0 317 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 9.6E-53 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 GTHT12_RS03130 5f12e6fa21886126a9ce09e7f1e89ce0 317 PRINTS PR00086 L-lactate dehydrogenase signature 8 32 9.6E-53 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 GTHT12_RS03130 5f12e6fa21886126a9ce09e7f1e89ce0 317 SUPERFAMILY SSF56327 147 311 8.22E-58 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 GTHT12_RS03130 5f12e6fa21886126a9ce09e7f1e89ce0 317 Gene3D G3DSA:3.40.50.720 7 149 1.4E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS03130 5f12e6fa21886126a9ce09e7f1e89ce0 317 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 11 308 1.2E-135 T 06-07-2017 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 GTHT12_RS03130 5f12e6fa21886126a9ce09e7f1e89ce0 317 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 8 146 1.3E-50 T 06-07-2017 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 GTHT12_RS03130 5f12e6fa21886126a9ce09e7f1e89ce0 317 PIRSF PIRSF000102 6 315 5.9E-114 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 GTHT12_RS03130 5f12e6fa21886126a9ce09e7f1e89ce0 317 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 176 182 - T 06-07-2017 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 GTHT12_RS03130 5f12e6fa21886126a9ce09e7f1e89ce0 317 SUPERFAMILY SSF51735 6 146 2.33E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS03130 5f12e6fa21886126a9ce09e7f1e89ce0 317 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 149 312 1.1E-37 T 06-07-2017 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 GTHT12_RS03130 5f12e6fa21886126a9ce09e7f1e89ce0 317 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 6 315 47.803 T 06-07-2017 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 GTHT12_RS09125 92f642768016c566668802f62d76a8e7 397 SUPERFAMILY SSF56645 10 229 1.31E-42 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 GTHT12_RS09125 92f642768016c566668802f62d76a8e7 397 PIRSF PIRSF016578 3 392 2.8E-33 T 06-07-2017 GTHT12_RS09125 92f642768016c566668802f62d76a8e7 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 129 221 1.3E-9 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 GTHT12_RS09125 92f642768016c566668802f62d76a8e7 397 SUPERFAMILY SSF47203 244 388 4.51E-31 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS09125 92f642768016c566668802f62d76a8e7 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 100 1.7E-15 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS09125 92f642768016c566668802f62d76a8e7 397 Gene3D G3DSA:2.40.110.10 139 222 4.6E-21 T 06-07-2017 GTHT12_RS09125 92f642768016c566668802f62d76a8e7 397 Gene3D G3DSA:1.10.540.10 10 102 3.1E-24 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS09125 92f642768016c566668802f62d76a8e7 397 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 250 367 3.4E-19 T 06-07-2017 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain GTHT12_RS09125 92f642768016c566668802f62d76a8e7 397 Gene3D G3DSA:1.20.140.10 223 390 9.4E-38 T 06-07-2017 GTHT12_RS12525 898f4a6ec7bf0b8adb0f78294e4e7fca 76 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 8 63 2.6E-23 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 GTHT12_RS12525 898f4a6ec7bf0b8adb0f78294e4e7fca 76 Pfam PF02609 Exonuclease VII small subunit 9 59 6.8E-22 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 GTHT12_RS12525 898f4a6ec7bf0b8adb0f78294e4e7fca 76 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 1 45 9.0E-15 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 GTHT12_RS12525 898f4a6ec7bf0b8adb0f78294e4e7fca 76 PIRSF PIRSF006488 1 75 2.9E-19 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 GTHT12_RS12525 898f4a6ec7bf0b8adb0f78294e4e7fca 76 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 8 68 15.228 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 GTHT12_RS12525 898f4a6ec7bf0b8adb0f78294e4e7fca 76 Gene3D G3DSA:1.10.287.1040 4 73 2.0E-25 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 GTHT12_RS12525 898f4a6ec7bf0b8adb0f78294e4e7fca 76 SUPERFAMILY SSF116842 3 72 1.44E-22 T 06-07-2017 GTHT12_RS11410 cc2141a11b1aec9961101726777d4cf5 550 Pfam PF01266 FAD dependent oxidoreductase 21 351 5.4E-53 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 GTHT12_RS11410 cc2141a11b1aec9961101726777d4cf5 550 SUPERFAMILY SSF51905 336 396 1.8E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS11410 cc2141a11b1aec9961101726777d4cf5 550 SUPERFAMILY SSF51905 15 284 1.8E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS11410 cc2141a11b1aec9961101726777d4cf5 550 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 43 1.3E-30 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 GTHT12_RS11410 cc2141a11b1aec9961101726777d4cf5 550 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 337 343 1.3E-30 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 GTHT12_RS11410 cc2141a11b1aec9961101726777d4cf5 550 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 94 106 1.3E-30 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 GTHT12_RS11410 cc2141a11b1aec9961101726777d4cf5 550 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 367 379 1.3E-30 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 GTHT12_RS11410 cc2141a11b1aec9961101726777d4cf5 550 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 20 32 1.3E-30 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 GTHT12_RS11410 cc2141a11b1aec9961101726777d4cf5 550 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 49 61 1.3E-30 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 GTHT12_RS11410 cc2141a11b1aec9961101726777d4cf5 550 Gene3D G3DSA:3.50.50.60 15 296 1.6E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS11410 cc2141a11b1aec9961101726777d4cf5 550 Gene3D G3DSA:3.50.50.60 443 459 1.6E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS11410 cc2141a11b1aec9961101726777d4cf5 550 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 372 382 - T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 GTHT12_RS11410 cc2141a11b1aec9961101726777d4cf5 550 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 404 529 4.0E-22 T 06-07-2017 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 GTHT12_RS11410 cc2141a11b1aec9961101726777d4cf5 550 SUPERFAMILY SSF54373 250 343 4.45E-13 T 06-07-2017 GTHT12_RS00760 c1233ba77d7ded2ead3eeae817ab28ea 430 ProSitePatterns PS00756 Protein secY signature 2. 165 182 - T 06-07-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 GTHT12_RS00760 c1233ba77d7ded2ead3eeae817ab28ea 430 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 429 29.181 T 06-07-2017 IPR026593 Protein translocase subunit SecY GTHT12_RS00760 c1233ba77d7ded2ead3eeae817ab28ea 430 SUPERFAMILY SSF103491 1 420 1.31E-131 T 06-07-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 GTHT12_RS00760 c1233ba77d7ded2ead3eeae817ab28ea 430 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 425 1.9E-150 T 06-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 GTHT12_RS00760 c1233ba77d7ded2ead3eeae817ab28ea 430 ProSitePatterns PS00755 Protein secY signature 1. 68 87 - T 06-07-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 GTHT12_RS00760 c1233ba77d7ded2ead3eeae817ab28ea 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 172 195 8.2E-102 T 06-07-2017 GTHT12_RS00760 c1233ba77d7ded2ead3eeae817ab28ea 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 269 288 8.2E-102 T 06-07-2017 GTHT12_RS00760 c1233ba77d7ded2ead3eeae817ab28ea 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 309 331 8.2E-102 T 06-07-2017 GTHT12_RS00760 c1233ba77d7ded2ead3eeae817ab28ea 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 67 87 8.2E-102 T 06-07-2017 GTHT12_RS00760 c1233ba77d7ded2ead3eeae817ab28ea 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 8.2E-102 T 06-07-2017 GTHT12_RS00760 c1233ba77d7ded2ead3eeae817ab28ea 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 109 132 8.2E-102 T 06-07-2017 GTHT12_RS00760 c1233ba77d7ded2ead3eeae817ab28ea 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 146 171 8.2E-102 T 06-07-2017 GTHT12_RS00760 c1233ba77d7ded2ead3eeae817ab28ea 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 398 416 8.2E-102 T 06-07-2017 GTHT12_RS00760 c1233ba77d7ded2ead3eeae817ab28ea 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 364 382 8.2E-102 T 06-07-2017 GTHT12_RS00760 c1233ba77d7ded2ead3eeae817ab28ea 430 PIRSF PIRSF004557 1 430 2.9E-128 T 06-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 GTHT12_RS00760 c1233ba77d7ded2ead3eeae817ab28ea 430 Gene3D G3DSA:1.10.3370.10 1 430 5.5E-155 T 06-07-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 GTHT12_RS00760 c1233ba77d7ded2ead3eeae817ab28ea 430 Pfam PF00344 SecY translocase 68 413 2.3E-116 T 06-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 GTHT12_RS06910 bc275d7a5bb3e2ff4f96b8f6ada59937 579 Gene3D G3DSA:1.20.1560.10 5 318 6.2E-70 T 06-07-2017 GTHT12_RS06910 bc275d7a5bb3e2ff4f96b8f6ada59937 579 SUPERFAMILY SSF90123 5 325 1.31E-71 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GTHT12_RS06910 bc275d7a5bb3e2ff4f96b8f6ada59937 579 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS06910 bc275d7a5bb3e2ff4f96b8f6ada59937 579 Pfam PF00005 ABC transporter 355 501 1.1E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS06910 bc275d7a5bb3e2ff4f96b8f6ada59937 579 Gene3D G3DSA:3.40.50.300 342 567 4.8E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06910 bc275d7a5bb3e2ff4f96b8f6ada59937 579 Pfam PF00664 ABC transporter transmembrane region 19 291 5.3E-42 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GTHT12_RS06910 bc275d7a5bb3e2ff4f96b8f6ada59937 579 SMART SM00382 362 554 3.4E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS06910 bc275d7a5bb3e2ff4f96b8f6ada59937 579 SUPERFAMILY SSF52540 329 573 4.14E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17860 79216f05e9df4a15407539b5f5d9572b 353 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 342 2.3E-83 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 GTHT12_RS17860 79216f05e9df4a15407539b5f5d9572b 353 Gene3D G3DSA:3.40.718.10 5 340 2.9E-113 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 GTHT12_RS17860 79216f05e9df4a15407539b5f5d9572b 353 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 239 258 - T 06-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 GTHT12_RS17860 79216f05e9df4a15407539b5f5d9572b 353 SUPERFAMILY SSF53659 3 349 3.26E-114 T 06-07-2017 GTHT12_RS17860 79216f05e9df4a15407539b5f5d9572b 353 SMART SM01329 5 345 2.6E-168 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 GTHT12_RS17860 79216f05e9df4a15407539b5f5d9572b 353 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 2 349 2.5E-187 T 06-07-2017 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 GTHT12_RS07455 984d37caff654532db9efe58deb40450 294 SUPERFAMILY SSF103481 36 141 1.96E-16 T 06-07-2017 GTHT12_RS07455 984d37caff654532db9efe58deb40450 294 SUPERFAMILY SSF103481 186 286 5.1E-10 T 06-07-2017 GTHT12_RS07455 984d37caff654532db9efe58deb40450 294 Pfam PF00892 EamA-like transporter family 5 138 1.6E-25 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 GTHT12_RS07455 984d37caff654532db9efe58deb40450 294 Pfam PF00892 EamA-like transporter family 152 282 3.3E-18 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 GTHT12_RS11420 fc15138d8fd26b8c17a72337f515cb81 465 SMART SM00387 353 465 6.2E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS11420 fc15138d8fd26b8c17a72337f515cb81 465 Pfam PF00672 HAMP domain 169 236 1.3E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS11420 fc15138d8fd26b8c17a72337f515cb81 465 Gene3D G3DSA:1.10.287.130 231 294 5.4E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS11420 fc15138d8fd26b8c17a72337f515cb81 465 Pfam PF00512 His Kinase A (phospho-acceptor) domain 242 306 6.3E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS11420 fc15138d8fd26b8c17a72337f515cb81 465 SUPERFAMILY SSF47384 224 306 6.47E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS11420 fc15138d8fd26b8c17a72337f515cb81 465 Gene3D G3DSA:3.30.565.10 295 464 2.2E-44 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS11420 fc15138d8fd26b8c17a72337f515cb81 465 SUPERFAMILY SSF158472 188 237 4.18E-7 T 06-07-2017 GTHT12_RS11420 fc15138d8fd26b8c17a72337f515cb81 465 SUPERFAMILY SSF55874 298 463 8.28E-39 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS11420 fc15138d8fd26b8c17a72337f515cb81 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 404 1.9E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS11420 fc15138d8fd26b8c17a72337f515cb81 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 418 1.9E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS11420 fc15138d8fd26b8c17a72337f515cb81 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 462 1.9E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS11420 fc15138d8fd26b8c17a72337f515cb81 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 443 1.9E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS11420 fc15138d8fd26b8c17a72337f515cb81 465 SMART SM00304 187 240 4.0E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS11420 fc15138d8fd26b8c17a72337f515cb81 465 SMART SM00388 241 308 1.4E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS11420 fc15138d8fd26b8c17a72337f515cb81 465 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 357 463 6.4E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS07300 8672ee2bf10dcbd72a6499b35f0d7fbe 104 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 103 23.849 T 06-07-2017 IPR002765 Uncharacterised protein family UPF0145 GTHT12_RS07300 8672ee2bf10dcbd72a6499b35f0d7fbe 104 Pfam PF01906 Putative heavy-metal-binding 1 103 1.8E-37 T 06-07-2017 IPR002765 Uncharacterised protein family UPF0145 GTHT12_RS07300 8672ee2bf10dcbd72a6499b35f0d7fbe 104 SUPERFAMILY SSF117782 2 104 1.31E-35 T 06-07-2017 IPR002765 Uncharacterised protein family UPF0145 GTHT12_RS07300 8672ee2bf10dcbd72a6499b35f0d7fbe 104 Gene3D G3DSA:3.30.110.70 1 103 7.2E-37 T 06-07-2017 IPR002765 Uncharacterised protein family UPF0145 GTHT12_RS05115 be60e5202bcc1cf9255cc6fe7f476ff9 242 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 9 199 3.6E-39 T 06-07-2017 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004|GO:0030288 GTHT12_RS05115 be60e5202bcc1cf9255cc6fe7f476ff9 242 Gene3D G3DSA:3.40.50.300 3 228 4.3E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05115 be60e5202bcc1cf9255cc6fe7f476ff9 242 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS05115 be60e5202bcc1cf9255cc6fe7f476ff9 242 Pfam PF00005 ABC transporter 23 163 3.1E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS05115 be60e5202bcc1cf9255cc6fe7f476ff9 242 SUPERFAMILY SSF52540 5 225 2.61E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05115 be60e5202bcc1cf9255cc6fe7f476ff9 242 SMART SM00382 31 210 2.4E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS10600 4a348b9b60a1e10cbea0c30e6ac2eed7 592 SUPERFAMILY SSF51338 12 76 6.0E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS10600 4a348b9b60a1e10cbea0c30e6ac2eed7 592 SUPERFAMILY SSF51338 325 370 6.0E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS10600 4a348b9b60a1e10cbea0c30e6ac2eed7 592 Gene3D G3DSA:2.30.40.10 12 105 3.1E-16 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS10600 4a348b9b60a1e10cbea0c30e6ac2eed7 592 Pfam PF13382 Adenine deaminase C-terminal domain 413 577 6.4E-35 T 06-07-2017 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 GTHT12_RS10600 4a348b9b60a1e10cbea0c30e6ac2eed7 592 Gene3D G3DSA:2.30.40.10 270 362 9.5E-15 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS10600 4a348b9b60a1e10cbea0c30e6ac2eed7 592 Pfam PF01979 Amidohydrolase family 72 356 2.8E-16 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 GTHT12_RS10600 4a348b9b60a1e10cbea0c30e6ac2eed7 592 SUPERFAMILY SSF51556 76 322 7.28E-19 T 06-07-2017 IPR032466 Metal-dependent hydrolase GTHT12_RS15430 9f855569efdc20196c9084051e1f8c51 290 SUPERFAMILY SSF54506 2 284 4.95E-52 T 06-07-2017 GTHT12_RS15430 9f855569efdc20196c9084051e1f8c51 290 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 283 2.0E-96 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 GTHT12_RS15430 9f855569efdc20196c9084051e1f8c51 290 Pfam PF01678 Diaminopimelate epimerase 161 276 3.6E-33 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 GTHT12_RS15430 9f855569efdc20196c9084051e1f8c51 290 Pfam PF01678 Diaminopimelate epimerase 6 129 3.7E-34 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 GTHT12_RS15430 9f855569efdc20196c9084051e1f8c51 290 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 4 284 38.454 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 GTHT12_RS15430 9f855569efdc20196c9084051e1f8c51 290 Gene3D G3DSA:3.10.310.10 3 125 2.5E-48 T 06-07-2017 GTHT12_RS15430 9f855569efdc20196c9084051e1f8c51 290 Gene3D G3DSA:3.10.310.10 126 272 3.4E-50 T 06-07-2017 GTHT12_RS15430 9f855569efdc20196c9084051e1f8c51 290 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 67 81 - T 06-07-2017 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 GTHT12_RS14100 0166b2022cfe4120fa45e60b78a08f0c 344 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 341 50.145 T 06-07-2017 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 GTHT12_RS14100 0166b2022cfe4120fa45e60b78a08f0c 344 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 21 88 4.8E-28 T 06-07-2017 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 GTHT12_RS14100 0166b2022cfe4120fa45e60b78a08f0c 344 SUPERFAMILY SSF55681 93 341 3.22E-82 T 06-07-2017 GTHT12_RS14100 0166b2022cfe4120fa45e60b78a08f0c 344 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 341 1.0E-116 T 06-07-2017 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 GTHT12_RS14100 0166b2022cfe4120fa45e60b78a08f0c 344 SUPERFAMILY SSF46589 13 100 1.05E-23 T 06-07-2017 IPR010978 tRNA-binding arm GO:0000166 GTHT12_RS14100 0166b2022cfe4120fa45e60b78a08f0c 344 Pfam PF01409 tRNA synthetases class II core domain (F) 93 341 1.7E-109 T 06-07-2017 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 GTHT12_RS14100 0166b2022cfe4120fa45e60b78a08f0c 344 Gene3D G3DSA:3.30.930.10 10 341 5.9E-136 T 06-07-2017 GTHT12_RS12690 848a24b2a0b78b6cd284aa707461f822 596 SUPERFAMILY SSF51998 104 517 1.04E-115 T 06-07-2017 GTHT12_RS12690 848a24b2a0b78b6cd284aa707461f822 596 SUPERFAMILY SSF51998 2 28 1.04E-115 T 06-07-2017 GTHT12_RS12690 848a24b2a0b78b6cd284aa707461f822 596 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 2 515 6.5E-144 T 06-07-2017 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 GTHT12_RS12690 848a24b2a0b78b6cd284aa707461f822 596 Gene3D G3DSA:3.20.70.20 176 332 1.0E-99 T 06-07-2017 GTHT12_RS12690 848a24b2a0b78b6cd284aa707461f822 596 Gene3D G3DSA:3.20.70.20 464 511 1.0E-99 T 06-07-2017 GTHT12_RS12690 848a24b2a0b78b6cd284aa707461f822 596 Gene3D G3DSA:3.20.70.20 2 28 1.0E-99 T 06-07-2017 GTHT12_RS12690 848a24b2a0b78b6cd284aa707461f822 596 Gene3D G3DSA:3.20.70.20 377 422 1.0E-99 T 06-07-2017 GTHT12_RS12690 848a24b2a0b78b6cd284aa707461f822 596 Gene3D G3DSA:3.20.70.20 100 118 1.0E-99 T 06-07-2017 GTHT12_RS12690 848a24b2a0b78b6cd284aa707461f822 596 PRINTS PR01183 Ribonucleotide reductase large chain signature 312 335 1.2E-35 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GTHT12_RS12690 848a24b2a0b78b6cd284aa707461f822 596 PRINTS PR01183 Ribonucleotide reductase large chain signature 377 404 1.2E-35 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GTHT12_RS12690 848a24b2a0b78b6cd284aa707461f822 596 PRINTS PR01183 Ribonucleotide reductase large chain signature 284 306 1.2E-35 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GTHT12_RS12690 848a24b2a0b78b6cd284aa707461f822 596 PRINTS PR01183 Ribonucleotide reductase large chain signature 246 269 1.2E-35 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GTHT12_RS12690 848a24b2a0b78b6cd284aa707461f822 596 PRINTS PR01183 Ribonucleotide reductase large chain signature 1 20 1.2E-35 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GTHT12_RS12690 848a24b2a0b78b6cd284aa707461f822 596 Pfam PF02867 Ribonucleotide reductase, barrel domain 2 505 5.2E-106 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 SUPERFAMILY SSF56059 670 929 1.62E-84 T 06-07-2017 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 Gene3D G3DSA:3.40.50.20 535 659 2.1E-56 T 06-07-2017 IPR016185 Pre-ATP-grasp domain GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 3.2E-81 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 670 866 1.0E-37 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 962 0.0 T 06-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 831 838 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 SUPERFAMILY SSF48108 394 549 4.32E-44 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 SUPERFAMILY SSF56059 128 399 1.1E-107 T 06-07-2017 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 Gene3D G3DSA:3.30.470.20 746 927 1.1E-58 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 Gene3D G3DSA:3.30.470.20 201 397 2.4E-75 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 SUPERFAMILY SSF52440 1 127 2.73E-47 T 06-07-2017 IPR016185 Pre-ATP-grasp domain GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 706 720 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 Gene3D G3DSA:1.10.1030.10 398 534 5.5E-44 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1025 12.578 T 06-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 Gene3D G3DSA:3.30.1490.20 142 200 4.3E-23 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 Gene3D G3DSA:3.30.1490.20 683 745 3.2E-17 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 3.1E-62 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 3.1E-62 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 3.1E-62 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 3.1E-62 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 3.1E-62 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 3.1E-62 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 3.1E-62 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 Gene3D G3DSA:3.40.50.20 4 108 8.5E-41 T 06-07-2017 IPR016185 Pre-ATP-grasp domain GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 424 543 3.2E-36 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 SMART SM01096 420 543 2.1E-55 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS04225 8f1f63f24eb4ca086ce6cf778a2a35c6 1042 SUPERFAMILY SSF52440 554 672 1.01E-46 T 06-07-2017 IPR016185 Pre-ATP-grasp domain GTHT12_RS01655 be77a5abd7a945e31a36ee82eeefb1e6 581 Pfam PF01979 Amidohydrolase family 79 363 4.9E-21 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 GTHT12_RS01655 be77a5abd7a945e31a36ee82eeefb1e6 581 Pfam PF13382 Adenine deaminase C-terminal domain 417 571 2.2E-34 T 06-07-2017 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 GTHT12_RS01655 be77a5abd7a945e31a36ee82eeefb1e6 581 SUPERFAMILY SSF51338 332 368 8.02E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS01655 be77a5abd7a945e31a36ee82eeefb1e6 581 SUPERFAMILY SSF51338 21 82 8.02E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS01655 be77a5abd7a945e31a36ee82eeefb1e6 581 Gene3D G3DSA:2.30.40.10 40 113 1.2E-10 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS01655 be77a5abd7a945e31a36ee82eeefb1e6 581 Gene3D G3DSA:2.30.40.10 278 368 1.4E-8 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS01655 be77a5abd7a945e31a36ee82eeefb1e6 581 SUPERFAMILY SSF51556 82 333 6.47E-12 T 06-07-2017 IPR032466 Metal-dependent hydrolase GTHT12_RS04460 70a74fbef4a888399987222b9b3d9f58 427 SUPERFAMILY SSF52413 299 421 1.96E-34 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 GTHT12_RS04460 70a74fbef4a888399987222b9b3d9f58 427 SUPERFAMILY SSF51735 1 192 4.86E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS04460 70a74fbef4a888399987222b9b3d9f58 427 Gene3D G3DSA:3.40.50.720 229 427 4.7E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS04460 70a74fbef4a888399987222b9b3d9f58 427 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 175 7.3E-60 T 06-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 GTHT12_RS04460 70a74fbef4a888399987222b9b3d9f58 427 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 407 3.9E-142 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 GTHT12_RS04460 70a74fbef4a888399987222b9b3d9f58 427 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 199 289 5.9E-38 T 06-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 GTHT12_RS04460 70a74fbef4a888399987222b9b3d9f58 427 SMART SM00984 312 411 7.1E-42 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 GTHT12_RS04460 70a74fbef4a888399987222b9b3d9f58 427 PIRSF PIRSF500134 1 427 2.2E-154 T 06-07-2017 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346 GTHT12_RS04460 70a74fbef4a888399987222b9b3d9f58 427 SUPERFAMILY SSF48179 198 291 9.69E-32 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GTHT12_RS04460 70a74fbef4a888399987222b9b3d9f58 427 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 312 411 3.9E-31 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 GTHT12_RS04460 70a74fbef4a888399987222b9b3d9f58 427 PIRSF PIRSF000124 1 426 6.7E-134 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 GTHT12_RS04460 70a74fbef4a888399987222b9b3d9f58 427 Gene3D G3DSA:1.20.5.100 202 226 2.4E-18 T 06-07-2017 GTHT12_RS04460 70a74fbef4a888399987222b9b3d9f58 427 Gene3D G3DSA:3.40.50.720 1 201 1.3E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS01190 b400f24f3315e495b6fee44de7ca2cfd 235 Gene3D G3DSA:3.40.30.10 1 208 3.7E-57 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS01190 b400f24f3315e495b6fee44de7ca2cfd 235 Pfam PF01323 DSBA-like thioredoxin domain 3 204 1.9E-55 T 06-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 GTHT12_RS01190 b400f24f3315e495b6fee44de7ca2cfd 235 SUPERFAMILY SSF52833 1 212 8.72E-56 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS16825 df4882504f2560328e28c7764b9d6508 315 SUPERFAMILY SSF75005 16 311 6.83E-59 T 06-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain GTHT12_RS16825 df4882504f2560328e28c7764b9d6508 315 Pfam PF08950 Protein of unknown function (DUF1861) 25 309 2.5E-133 T 06-07-2017 IPR015045 Protein of unknown function DUF1861 GTHT12_RS00735 adcbfc8b67543d5e91546672494fde0e 178 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 06-07-2017 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00735 adcbfc8b67543d5e91546672494fde0e 178 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 1.1E-80 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 GTHT12_RS00735 adcbfc8b67543d5e91546672494fde0e 178 PIRSF PIRSF002162 1 177 3.0E-53 T 06-07-2017 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00735 adcbfc8b67543d5e91546672494fde0e 178 Pfam PF00347 Ribosomal protein L6 11 82 1.9E-26 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00735 adcbfc8b67543d5e91546672494fde0e 178 Pfam PF00347 Ribosomal protein L6 90 164 6.3E-21 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00735 adcbfc8b67543d5e91546672494fde0e 178 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 40.706 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 GTHT12_RS00735 adcbfc8b67543d5e91546672494fde0e 178 SUPERFAMILY SSF56053 1 82 8.63E-32 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00735 adcbfc8b67543d5e91546672494fde0e 178 SUPERFAMILY SSF56053 83 177 2.24E-35 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00735 adcbfc8b67543d5e91546672494fde0e 178 PRINTS PR00059 Ribosomal protein L6 signature 141 162 1.3E-35 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 GTHT12_RS00735 adcbfc8b67543d5e91546672494fde0e 178 PRINTS PR00059 Ribosomal protein L6 signature 99 115 1.3E-35 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 GTHT12_RS00735 adcbfc8b67543d5e91546672494fde0e 178 PRINTS PR00059 Ribosomal protein L6 signature 71 96 1.3E-35 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 GTHT12_RS00735 adcbfc8b67543d5e91546672494fde0e 178 Gene3D G3DSA:3.90.930.12 2 82 9.7E-38 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00735 adcbfc8b67543d5e91546672494fde0e 178 Gene3D G3DSA:3.90.930.12 83 177 2.2E-40 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00010 156210ca8de5dff568a655c035e8ef0a 378 Gene3D G3DSA:3.10.150.10 257 377 4.8E-33 T 06-07-2017 GTHT12_RS00010 156210ca8de5dff568a655c035e8ef0a 378 Pfam PF02767 DNA polymerase III beta subunit, central domain 136 251 4.3E-38 T 06-07-2017 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS00010 156210ca8de5dff568a655c035e8ef0a 378 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 2 127 1.6E-38 T 06-07-2017 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS00010 156210ca8de5dff568a655c035e8ef0a 378 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 254 376 6.1E-34 T 06-07-2017 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS00010 156210ca8de5dff568a655c035e8ef0a 378 SUPERFAMILY SSF55979 2 127 1.22E-23 T 06-07-2017 GTHT12_RS00010 156210ca8de5dff568a655c035e8ef0a 378 PIRSF PIRSF000804 1 378 4.0E-117 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS00010 156210ca8de5dff568a655c035e8ef0a 378 SUPERFAMILY SSF55979 133 250 6.63E-28 T 06-07-2017 GTHT12_RS00010 156210ca8de5dff568a655c035e8ef0a 378 SUPERFAMILY SSF55979 254 377 4.82E-31 T 06-07-2017 GTHT12_RS00010 156210ca8de5dff568a655c035e8ef0a 378 Gene3D G3DSA:3.10.150.10 2 129 1.2E-29 T 06-07-2017 GTHT12_RS00010 156210ca8de5dff568a655c035e8ef0a 378 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 2 377 3.5E-123 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS00010 156210ca8de5dff568a655c035e8ef0a 378 Gene3D G3DSA:3.10.150.10 130 256 5.3E-38 T 06-07-2017 GTHT12_RS00010 156210ca8de5dff568a655c035e8ef0a 378 SMART SM00480 17 373 2.1E-164 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS14230 4cd80f26a8a776d8e83e01b6ba7573d0 423 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 2 423 6.2E-227 T 06-07-2017 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 GTHT12_RS14230 4cd80f26a8a776d8e83e01b6ba7573d0 423 SMART SM01329 21 418 1.1E-193 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 GTHT12_RS14230 4cd80f26a8a776d8e83e01b6ba7573d0 423 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 307 326 - T 06-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 GTHT12_RS14230 4cd80f26a8a776d8e83e01b6ba7573d0 423 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 22 417 8.9E-125 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 GTHT12_RS14230 4cd80f26a8a776d8e83e01b6ba7573d0 423 SUPERFAMILY SSF53659 3 422 2.5E-145 T 06-07-2017 GTHT12_RS14230 4cd80f26a8a776d8e83e01b6ba7573d0 423 Gene3D G3DSA:3.40.718.10 3 423 2.7E-176 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 Pfam PF01627 Hpt domain 5 98 1.5E-20 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 Pfam PF07194 P2 response regulator binding domain 162 241 7.9E-27 T 06-07-2017 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 289 347 1.8E-12 T 06-07-2017 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 Gene3D G3DSA:2.40.50.180 560 622 2.0E-15 T 06-07-2017 GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 Gene3D G3DSA:2.30.30.40 536 557 1.7E-23 T 06-07-2017 GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 Gene3D G3DSA:2.30.30.40 623 667 1.7E-23 T 06-07-2017 GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 Gene3D G3DSA:3.30.70.1110 159 241 5.9E-32 T 06-07-2017 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 396 535 1.2E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 SUPERFAMILY SSF47226 2 123 1.27E-33 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 SUPERFAMILY SSF50341 535 667 3.4E-33 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 SMART SM00073 3 100 1.6E-36 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 SMART SM00260 528 667 1.0E-42 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 SUPERFAMILY SSF47384 289 349 9.42E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 Gene3D G3DSA:3.30.565.10 349 535 1.9E-42 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 PRINTS PR00344 Bacterial sensor protein C-terminal signature 496 514 3.6E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 490 3.6E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 452 3.6E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 PRINTS PR00344 Bacterial sensor protein C-terminal signature 520 533 3.6E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 Gene3D G3DSA:1.10.287.560 288 348 1.1E-19 T 06-07-2017 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 SUPERFAMILY SSF55874 350 534 1.11E-44 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 Pfam PF01584 CheW-like domain 541 667 1.7E-25 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 SUPERFAMILY SSF55052 159 241 1.05E-23 T 06-07-2017 IPR015162 CheY binding GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 SMART SM00387 393 536 1.2E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 SMART SM01231 288 348 2.9E-17 T 06-07-2017 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 GTHT12_RS06445 6d563688f5b1b6acb35a862981db552f 668 Gene3D G3DSA:1.20.120.160 1 134 9.0E-46 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 GTHT12_RS10025 c04fd31556af8421c76fbcd0ceb559a0 333 Pfam PF13407 Periplasmic binding protein domain 48 296 2.1E-54 T 06-07-2017 IPR025997 Periplasmic binding protein GTHT12_RS10025 c04fd31556af8421c76fbcd0ceb559a0 333 SUPERFAMILY SSF53822 45 329 1.43E-67 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS10025 c04fd31556af8421c76fbcd0ceb559a0 333 Gene3D G3DSA:3.40.50.2300 162 300 6.5E-46 T 06-07-2017 GTHT12_RS10025 c04fd31556af8421c76fbcd0ceb559a0 333 Gene3D G3DSA:3.40.50.2300 45 161 2.0E-39 T 06-07-2017 GTHT12_RS08540 c127ff83fbff9220bf10f9a9e619e07d 149 Gene3D G3DSA:3.10.129.10 6 139 2.8E-23 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS08540 c127ff83fbff9220bf10f9a9e619e07d 149 Pfam PF13452 N-terminal half of MaoC dehydratase 5 132 1.6E-36 T 06-07-2017 GTHT12_RS08540 c127ff83fbff9220bf10f9a9e619e07d 149 SUPERFAMILY SSF54637 6 139 1.47E-28 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS08540 c127ff83fbff9220bf10f9a9e619e07d 149 PIRSF PIRSF018072 1 145 3.3E-40 T 06-07-2017 IPR016709 Uncharacterised protein family UPF0336 GTHT12_RS13585 fa32ff4b21fc9e21d09f1f5ddf99145f 276 SUPERFAMILY SSF51690 109 273 2.63E-61 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 GTHT12_RS13585 fa32ff4b21fc9e21d09f1f5ddf99145f 276 SUPERFAMILY SSF54675 2 108 3.92E-31 T 06-07-2017 GTHT12_RS13585 fa32ff4b21fc9e21d09f1f5ddf99145f 276 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 18 107 2.0E-27 T 06-07-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 GTHT12_RS13585 fa32ff4b21fc9e21d09f1f5ddf99145f 276 Gene3D G3DSA:3.20.20.70 130 265 3.0E-63 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS13585 fa32ff4b21fc9e21d09f1f5ddf99145f 276 Gene3D G3DSA:3.90.1170.20 2 129 3.1E-47 T 06-07-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 GTHT12_RS13585 fa32ff4b21fc9e21d09f1f5ddf99145f 276 PIRSF PIRSF006250 1 276 1.9E-98 T 06-07-2017 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 GTHT12_RS13585 fa32ff4b21fc9e21d09f1f5ddf99145f 276 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 10 273 7.3E-103 T 06-07-2017 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 GTHT12_RS13585 fa32ff4b21fc9e21d09f1f5ddf99145f 276 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 109 272 5.3E-63 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 GTHT12_RS07800 01388eac208826687d2f01bc8dbc250f 459 Pfam PF00082 Subtilase family 199 441 4.1E-51 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 GTHT12_RS07800 01388eac208826687d2f01bc8dbc250f 459 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 239 249 - T 06-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site GTHT12_RS07800 01388eac208826687d2f01bc8dbc250f 459 Gene3D G3DSA:3.40.50.200 142 453 1.2E-101 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 GTHT12_RS07800 01388eac208826687d2f01bc8dbc250f 459 SUPERFAMILY SSF52743 178 454 1.31E-94 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 GTHT12_RS07800 01388eac208826687d2f01bc8dbc250f 459 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 202 213 - T 06-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site GTHT12_RS07800 01388eac208826687d2f01bc8dbc250f 459 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 391 401 - T 06-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site GTHT12_RS07800 01388eac208826687d2f01bc8dbc250f 459 PRINTS PR00723 Subtilisin serine protease family (S8) signature 235 248 6.8E-19 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related GTHT12_RS07800 01388eac208826687d2f01bc8dbc250f 459 PRINTS PR00723 Subtilisin serine protease family (S8) signature 390 406 6.8E-19 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related GTHT12_RS07800 01388eac208826687d2f01bc8dbc250f 459 PRINTS PR00723 Subtilisin serine protease family (S8) signature 197 216 6.8E-19 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related GTHT12_RS14210 4fc8d52f0adec2cd488bba1269dc30c4 583 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 470 581 3.2E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS14210 4fc8d52f0adec2cd488bba1269dc30c4 583 SMART SM00387 470 582 6.8E-44 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS14210 4fc8d52f0adec2cd488bba1269dc30c4 583 SUPERFAMILY SSF47384 344 425 2.35E-21 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS14210 4fc8d52f0adec2cd488bba1269dc30c4 583 SUPERFAMILY SSF55785 231 350 1.54E-10 T 06-07-2017 IPR000014 PAS domain GTHT12_RS14210 4fc8d52f0adec2cd488bba1269dc30c4 583 Pfam PF00672 HAMP domain 166 232 3.1E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS14210 4fc8d52f0adec2cd488bba1269dc30c4 583 Pfam PF00989 PAS fold 243 349 7.5E-10 T 06-07-2017 IPR013767 PAS fold GO:0006355 GTHT12_RS14210 4fc8d52f0adec2cd488bba1269dc30c4 583 Pfam PF00512 His Kinase A (phospho-acceptor) domain 359 424 2.3E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS14210 4fc8d52f0adec2cd488bba1269dc30c4 583 Gene3D G3DSA:3.30.450.20 29 157 1.6E-30 T 06-07-2017 GTHT12_RS14210 4fc8d52f0adec2cd488bba1269dc30c4 583 PRINTS PR00344 Bacterial sensor protein C-terminal signature 507 521 4.8E-20 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS14210 4fc8d52f0adec2cd488bba1269dc30c4 583 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 535 4.8E-20 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS14210 4fc8d52f0adec2cd488bba1269dc30c4 583 PRINTS PR00344 Bacterial sensor protein C-terminal signature 566 579 4.8E-20 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS14210 4fc8d52f0adec2cd488bba1269dc30c4 583 PRINTS PR00344 Bacterial sensor protein C-terminal signature 542 560 4.8E-20 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS14210 4fc8d52f0adec2cd488bba1269dc30c4 583 SMART SM00091 242 308 3.4E-5 T 06-07-2017 IPR000014 PAS domain GTHT12_RS14210 4fc8d52f0adec2cd488bba1269dc30c4 583 Pfam PF16736 Single Cache-like 33 148 6.2E-25 T 06-07-2017 IPR031967 PhoR, single Cache-like domain GTHT12_RS14210 4fc8d52f0adec2cd488bba1269dc30c4 583 Gene3D G3DSA:3.30.565.10 412 580 2.3E-54 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS14210 4fc8d52f0adec2cd488bba1269dc30c4 583 SUPERFAMILY SSF158472 185 233 2.22E-6 T 06-07-2017 GTHT12_RS14210 4fc8d52f0adec2cd488bba1269dc30c4 583 Gene3D G3DSA:3.30.450.20 240 349 2.0E-14 T 06-07-2017 GTHT12_RS14210 4fc8d52f0adec2cd488bba1269dc30c4 583 SUPERFAMILY SSF55874 415 580 5.76E-52 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS14210 4fc8d52f0adec2cd488bba1269dc30c4 583 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 241 357 5.9E-6 T 06-07-2017 IPR000014 PAS domain GTHT12_RS14210 4fc8d52f0adec2cd488bba1269dc30c4 583 SMART SM00388 358 425 1.4E-22 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS14210 4fc8d52f0adec2cd488bba1269dc30c4 583 Gene3D G3DSA:1.10.287.130 350 411 9.2E-22 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS03510 762a93b94ced32aa121b8617f4ce54c9 67 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 67 9.7E-20 T 06-07-2017 IPR010035 ThiS, thiamine-biosynthesis GTHT12_RS03510 762a93b94ced32aa121b8617f4ce54c9 67 Gene3D G3DSA:3.10.20.30 3 67 4.9E-23 T 06-07-2017 IPR012675 Beta-grasp domain GTHT12_RS03510 762a93b94ced32aa121b8617f4ce54c9 67 Pfam PF02597 ThiS family 7 67 5.8E-11 T 06-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 GTHT12_RS03510 762a93b94ced32aa121b8617f4ce54c9 67 SUPERFAMILY SSF54285 2 66 1.64E-17 T 06-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp GTHT12_RS03880 ad3004d93e65477d879faeb111eca15b 615 Pfam PF13537 Glutamine amidotransferase domain 48 169 6.8E-47 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain GTHT12_RS03880 ad3004d93e65477d879faeb111eca15b 615 Pfam PF00733 Asparagine synthase 242 579 6.2E-97 T 06-07-2017 IPR001962 Asparagine synthase GO:0004066|GO:0006529 GTHT12_RS03880 ad3004d93e65477d879faeb111eca15b 615 SUPERFAMILY SSF56235 1 226 5.58E-65 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal GTHT12_RS03880 ad3004d93e65477d879faeb111eca15b 615 SUPERFAMILY SSF52402 229 396 9.69E-78 T 06-07-2017 GTHT12_RS03880 ad3004d93e65477d879faeb111eca15b 615 SUPERFAMILY SSF52402 454 576 9.69E-78 T 06-07-2017 GTHT12_RS03880 ad3004d93e65477d879faeb111eca15b 615 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 534 4.6E-168 T 06-07-2017 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 GTHT12_RS03880 ad3004d93e65477d879faeb111eca15b 615 PIRSF PIRSF001589 1 614 4.0E-145 T 06-07-2017 GTHT12_RS03880 ad3004d93e65477d879faeb111eca15b 615 Gene3D G3DSA:3.40.50.620 427 606 1.2E-85 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS03880 ad3004d93e65477d879faeb111eca15b 615 Gene3D G3DSA:3.40.50.620 225 392 1.2E-85 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS03880 ad3004d93e65477d879faeb111eca15b 615 Gene3D G3DSA:3.60.20.10 1 224 8.2E-76 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal GTHT12_RS09150 66a756e7bc6b0b7aacae07eb5958bf93 563 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 6 558 1.5E-270 T 06-07-2017 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 GTHT12_RS09150 66a756e7bc6b0b7aacae07eb5958bf93 563 Gene3D G3DSA:3.20.20.80 177 480 7.6E-129 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS09150 66a756e7bc6b0b7aacae07eb5958bf93 563 Gene3D G3DSA:3.20.20.80 4 105 7.6E-129 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS09150 66a756e7bc6b0b7aacae07eb5958bf93 563 SUPERFAMILY SSF51445 5 478 1.43E-163 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS09150 66a756e7bc6b0b7aacae07eb5958bf93 563 Pfam PF16657 Maltogenic Amylase, C-terminal domain 481 554 2.3E-8 T 06-07-2017 IPR032091 Maltogenic Amylase, C-terminal GTHT12_RS09150 66a756e7bc6b0b7aacae07eb5958bf93 563 Gene3D G3DSA:3.90.400.10 106 176 2.3E-31 T 06-07-2017 GTHT12_RS09150 66a756e7bc6b0b7aacae07eb5958bf93 563 SUPERFAMILY SSF51011 481 560 5.97E-19 T 06-07-2017 GTHT12_RS09150 66a756e7bc6b0b7aacae07eb5958bf93 563 Gene3D G3DSA:2.60.40.1180 483 560 2.8E-23 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta GTHT12_RS09150 66a756e7bc6b0b7aacae07eb5958bf93 563 Pfam PF00128 Alpha amylase, catalytic domain 29 378 2.0E-131 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GTHT12_RS09150 66a756e7bc6b0b7aacae07eb5958bf93 563 SMART SM00642 14 420 8.9E-170 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GTHT12_RS00315 c97c7cdf9c5487f19db808058c9afcf8 486 SUPERFAMILY SSF101386 231 332 5.56E-25 T 06-07-2017 GTHT12_RS00315 c97c7cdf9c5487f19db808058c9afcf8 486 TIGRFAM TIGR00444 mazG: MazG family protein 238 482 9.0E-102 T 06-07-2017 IPR011551 NTP pyrophosphohydrolase MazG GTHT12_RS00315 c97c7cdf9c5487f19db808058c9afcf8 486 PIRSF PIRSF002845 1 486 4.1E-219 T 06-07-2017 IPR024180 Bifunctional tetrapyrrole methylase/MazG NTP pyrophosphohydrolase, predicted GTHT12_RS00315 c97c7cdf9c5487f19db808058c9afcf8 486 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 394 451 3.3E-7 T 06-07-2017 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core GTHT12_RS00315 c97c7cdf9c5487f19db808058c9afcf8 486 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 254 327 2.8E-28 T 06-07-2017 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core GTHT12_RS00315 c97c7cdf9c5487f19db808058c9afcf8 486 SUPERFAMILY SSF53790 3 256 2.33E-30 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS00315 c97c7cdf9c5487f19db808058c9afcf8 486 Gene3D G3DSA:3.40.1010.10 3 117 8.8E-11 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS00315 c97c7cdf9c5487f19db808058c9afcf8 486 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 205 1.9E-22 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS00315 c97c7cdf9c5487f19db808058c9afcf8 486 SUPERFAMILY SSF101386 362 461 1.19E-24 T 06-07-2017 GTHT12_RS00315 c97c7cdf9c5487f19db808058c9afcf8 486 Gene3D G3DSA:1.10.287.1080 248 299 3.6E-10 T 06-07-2017 GTHT12_RS00315 c97c7cdf9c5487f19db808058c9afcf8 486 Gene3D G3DSA:1.10.287.1080 359 444 8.8E-14 T 06-07-2017 GTHT12_RS06450 a70a9a34e85f47d1b27d5ac17d5df86d 145 Gene3D G3DSA:2.40.50.180 48 85 4.9E-12 T 06-07-2017 GTHT12_RS06450 a70a9a34e85f47d1b27d5ac17d5df86d 145 SMART SM00260 6 143 1.3E-44 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 GTHT12_RS06450 a70a9a34e85f47d1b27d5ac17d5df86d 145 Gene3D G3DSA:2.30.30.40 86 137 7.8E-12 T 06-07-2017 GTHT12_RS06450 a70a9a34e85f47d1b27d5ac17d5df86d 145 SUPERFAMILY SSF50341 9 144 3.53E-39 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 GTHT12_RS06450 a70a9a34e85f47d1b27d5ac17d5df86d 145 Pfam PF01584 CheW-like domain 11 144 5.8E-39 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 GTHT12_RS09755 3a729d82885128695e7686a64cd691ec 439 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 13 429 1.8E-170 T 06-07-2017 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 GTHT12_RS09755 3a729d82885128695e7686a64cd691ec 439 Pfam PF02378 Phosphotransferase system, EIIC 30 354 3.5E-73 T 06-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 GTHT12_RS09755 3a729d82885128695e7686a64cd691ec 439 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 13 429 1.8E-170 T 06-07-2017 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 GTHT12_RS09755 3a729d82885128695e7686a64cd691ec 439 PIRSF PIRSF006351 2 437 7.9E-146 T 06-07-2017 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 GTHT12_RS11860 4e311f7aa20db3d309a1b0e435a6e2c6 86 PIRSF PIRSF010606 1 86 2.2E-43 T 06-07-2017 IPR016571 Spore coat assembly protein CotJB GTHT12_RS11860 4e311f7aa20db3d309a1b0e435a6e2c6 86 Pfam PF12652 CotJB protein 11 85 4.7E-29 T 06-07-2017 IPR024207 Spore coat assembly protein CotJB, domain GTHT12_RS18060 66fdc2b6440117d62009d9bbf73d0b38 368 Gene3D G3DSA:3.30.565.10 251 329 7.3E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS18060 66fdc2b6440117d62009d9bbf73d0b38 368 SUPERFAMILY SSF55874 254 366 2.1E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS18060 66fdc2b6440117d62009d9bbf73d0b38 368 Pfam PF07730 Histidine kinase 177 243 2.7E-15 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 GTHT12_RS07770 aabbac49ce314430aa6de693a38d6297 221 Pfam PF02581 Thiamine monophosphate synthase/TENI 15 198 3.5E-64 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GTHT12_RS07770 aabbac49ce314430aa6de693a38d6297 221 SUPERFAMILY SSF51391 12 214 1.57E-71 T 06-07-2017 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GTHT12_RS07770 aabbac49ce314430aa6de693a38d6297 221 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 15 210 2.7E-67 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GTHT12_RS07770 aabbac49ce314430aa6de693a38d6297 221 Gene3D G3DSA:3.20.20.70 3 217 2.9E-78 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS07770 aabbac49ce314430aa6de693a38d6297 221 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 13 216 29.881 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GTHT12_RS01445 747e540781a3bd211a4b7e708bd43620 643 Gene3D G3DSA:1.20.58.410 579 632 4.1E-4 T 06-07-2017 GTHT12_RS01445 747e540781a3bd211a4b7e708bd43620 643 Gene3D G3DSA:1.20.58.410 99 136 3.7E-5 T 06-07-2017 GTHT12_RS01445 747e540781a3bd211a4b7e708bd43620 643 Gene3D G3DSA:3.40.50.300 330 559 3.2E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01445 747e540781a3bd211a4b7e708bd43620 643 Pfam PF16326 ABC transporter C-terminal domain 573 639 1.2E-16 T 06-07-2017 IPR032524 ABC transporter Uup, C-terminal GO:0003677 GTHT12_RS01445 747e540781a3bd211a4b7e708bd43620 643 ProSitePatterns PS00211 ABC transporters family signature. 450 464 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS01445 747e540781a3bd211a4b7e708bd43620 643 Pfam PF00005 ABC transporter 349 478 1.4E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS01445 747e540781a3bd211a4b7e708bd43620 643 Pfam PF00005 ABC transporter 19 196 7.6E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS01445 747e540781a3bd211a4b7e708bd43620 643 SMART SM00382 28 248 6.3E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS01445 747e540781a3bd211a4b7e708bd43620 643 SMART SM00382 357 522 5.0E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS01445 747e540781a3bd211a4b7e708bd43620 643 SUPERFAMILY SSF52540 4 249 5.56E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01445 747e540781a3bd211a4b7e708bd43620 643 SUPERFAMILY SSF52540 317 534 9.13E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01445 747e540781a3bd211a4b7e708bd43620 643 Gene3D G3DSA:3.40.50.300 143 291 5.8E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01445 747e540781a3bd211a4b7e708bd43620 643 Gene3D G3DSA:3.40.50.300 5 98 5.8E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01445 747e540781a3bd211a4b7e708bd43620 643 Pfam PF12848 ABC transporter 235 319 2.5E-29 T 06-07-2017 IPR032781 ABC-transporter extension domain GTHT12_RS01445 747e540781a3bd211a4b7e708bd43620 643 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS17330 fe188ef0decc734038dc0aa4f9ba2538 119 ProDom PD053619 EPUA PRECURSOR SIGNAL PEPTIDE YFDG EXTRACELLULAR OB2955 BH3736 GBS0884 SMU.1524C 59 113 8.0E-18 T 06-07-2017 IPR024596 DNA-directed RNA polymerase subunit beta/EpuA GTHT12_RS17330 fe188ef0decc734038dc0aa4f9ba2538 119 Pfam PF11772 DNA-directed RNA polymerase subunit beta 72 117 5.0E-18 T 06-07-2017 IPR024596 DNA-directed RNA polymerase subunit beta/EpuA GTHT12_RS05425 425ab22268fa369fd5fb66896a83371f 539 Gene3D G3DSA:2.30.38.10 357 432 4.2E-27 T 06-07-2017 GTHT12_RS05425 425ab22268fa369fd5fb66896a83371f 539 Gene3D G3DSA:3.30.300.30 436 535 8.7E-36 T 06-07-2017 GTHT12_RS05425 425ab22268fa369fd5fb66896a83371f 539 Gene3D G3DSA:3.40.50.980 198 356 2.9E-43 T 06-07-2017 GTHT12_RS05425 425ab22268fa369fd5fb66896a83371f 539 Pfam PF00501 AMP-binding enzyme 30 440 1.9E-114 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GTHT12_RS05425 425ab22268fa369fd5fb66896a83371f 539 SUPERFAMILY SSF56801 9 535 1.02E-164 T 06-07-2017 GTHT12_RS05425 425ab22268fa369fd5fb66896a83371f 539 Pfam PF13193 AMP-binding enzyme C-terminal domain 450 525 1.3E-23 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain GTHT12_RS05425 425ab22268fa369fd5fb66896a83371f 539 Gene3D G3DSA:3.40.50.980 22 197 9.4E-42 T 06-07-2017 GTHT12_RS05425 425ab22268fa369fd5fb66896a83371f 539 ProSitePatterns PS00455 Putative AMP-binding domain signature. 191 202 - T 06-07-2017 IPR020845 AMP-binding, conserved site GTHT12_RS01700 60df6147674fd4ee38e9e2ce84f894e9 491 Pfam PF01593 Flavin containing amine oxidoreductase 39 486 2.7E-74 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 GTHT12_RS01700 60df6147674fd4ee38e9e2ce84f894e9 491 Gene3D G3DSA:1.10.405.10 130 230 3.6E-25 T 06-07-2017 GTHT12_RS01700 60df6147674fd4ee38e9e2ce84f894e9 491 Gene3D G3DSA:3.50.50.60 29 57 3.0E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS01700 60df6147674fd4ee38e9e2ce84f894e9 491 Gene3D G3DSA:3.50.50.60 428 488 3.0E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS01700 60df6147674fd4ee38e9e2ce84f894e9 491 Gene3D G3DSA:3.50.50.60 243 327 3.0E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS01700 60df6147674fd4ee38e9e2ce84f894e9 491 SUPERFAMILY SSF54373 327 437 9.16E-31 T 06-07-2017 GTHT12_RS01700 60df6147674fd4ee38e9e2ce84f894e9 491 PRINTS PR00757 Flavin-containing amine oxidase signature 31 50 1.3E-9 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 GTHT12_RS01700 60df6147674fd4ee38e9e2ce84f894e9 491 PRINTS PR00757 Flavin-containing amine oxidase signature 331 350 1.3E-9 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 GTHT12_RS01700 60df6147674fd4ee38e9e2ce84f894e9 491 PRINTS PR00757 Flavin-containing amine oxidase signature 468 485 1.3E-9 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 GTHT12_RS01700 60df6147674fd4ee38e9e2ce84f894e9 491 PRINTS PR00757 Flavin-containing amine oxidase signature 418 437 1.3E-9 T 06-07-2017 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 GTHT12_RS01700 60df6147674fd4ee38e9e2ce84f894e9 491 Gene3D G3DSA:3.90.660.10 58 129 2.2E-65 T 06-07-2017 GTHT12_RS01700 60df6147674fd4ee38e9e2ce84f894e9 491 Gene3D G3DSA:3.90.660.10 331 427 2.2E-65 T 06-07-2017 GTHT12_RS01700 60df6147674fd4ee38e9e2ce84f894e9 491 SUPERFAMILY SSF51905 449 488 1.32E-69 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS01700 60df6147674fd4ee38e9e2ce84f894e9 491 SUPERFAMILY SSF51905 29 346 1.32E-69 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS18095 f7a31abd6250dd509a6284b0ecb93405 49 Pfam PF14116 YyzF-like protein 4 48 6.3E-20 T 06-07-2017 IPR025626 YyzF-like protein GTHT12_RS18095 f7a31abd6250dd509a6284b0ecb93405 49 TIGRFAM TIGR04129 CxxH_BA5709: CxxH/CxxC protein, BA_5709 family 2 47 2.6E-20 T 06-07-2017 IPR025626 YyzF-like protein GTHT12_RS13295 7baa465d51198771625148acd4995c16 377 PIRSF PIRSF001434 1 377 4.9E-153 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 GTHT12_RS13295 7baa465d51198771625148acd4995c16 377 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 376 9.3E-162 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 GTHT12_RS13295 7baa465d51198771625148acd4995c16 377 Gene3D G3DSA:3.90.1150.10 244 376 8.0E-56 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS13295 7baa465d51198771625148acd4995c16 377 SUPERFAMILY SSF53383 6 376 6.99E-127 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS13295 7baa465d51198771625148acd4995c16 377 Gene3D G3DSA:3.40.640.10 3 243 5.7E-102 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS13295 7baa465d51198771625148acd4995c16 377 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 187 201 - T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 SUPERFAMILY SSF50249 549 649 7.83E-33 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 Gene3D G3DSA:2.40.50.140 544 650 1.9E-40 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 Gene3D G3DSA:3.40.50.620 3 114 5.3E-83 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 Gene3D G3DSA:3.40.50.620 226 334 5.3E-83 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 SUPERFAMILY SSF47323 351 563 4.67E-49 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 SUPERFAMILY SSF52374 3 348 1.86E-123 T 06-07-2017 GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 156 512 1.6E-123 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 Pfam PF09334 tRNA synthetases class I (M) 155 361 3.8E-72 T 06-07-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 Pfam PF09334 tRNA synthetases class I (M) 6 150 1.3E-53 T 06-07-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 517 650 4.0E-46 T 06-07-2017 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 PRINTS PR01041 Methionyl-tRNA synthetase signature 88 99 3.6E-34 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 PRINTS PR01041 Methionyl-tRNA synthetase signature 257 272 3.6E-34 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 PRINTS PR01041 Methionyl-tRNA synthetase signature 349 360 3.6E-34 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 3.6E-34 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 PRINTS PR01041 Methionyl-tRNA synthetase signature 8 21 3.6E-34 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 PRINTS PR01041 Methionyl-tRNA synthetase signature 224 235 3.6E-34 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 Pfam PF08264 Anticodon-binding domain of tRNA 384 525 2.2E-7 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 Pfam PF01588 Putative tRNA binding domain 556 648 8.6E-29 T 06-07-2017 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 510 53.418 T 06-07-2017 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 Gene3D G3DSA:1.10.730.10 339 511 5.8E-57 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 24 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS00205 e3cef42a00a02b2560a0f00887593b48 650 Gene3D G3DSA:2.170.220.10 117 225 2.5E-49 T 06-07-2017 GTHT12_RS12735 ad0491671c834ea3cee0faa48022484c 365 Gene3D G3DSA:2.40.30.110 282 356 1.0E-28 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 GTHT12_RS12735 ad0491671c834ea3cee0faa48022484c 365 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 362 49.644 T 06-07-2017 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 GTHT12_RS12735 ad0491671c834ea3cee0faa48022484c 365 PIRSF PIRSF006487 1 365 3.3E-102 T 06-07-2017 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 GTHT12_RS12735 ad0491671c834ea3cee0faa48022484c 365 SUPERFAMILY SSF101790 273 362 1.19E-27 T 06-07-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain GTHT12_RS12735 ad0491671c834ea3cee0faa48022484c 365 Gene3D G3DSA:3.30.70.1400 53 136 2.5E-32 T 06-07-2017 GTHT12_RS12735 ad0491671c834ea3cee0faa48022484c 365 SUPERFAMILY SSF103025 2 281 1.38E-102 T 06-07-2017 GTHT12_RS12735 ad0491671c834ea3cee0faa48022484c 365 Gene3D G3DSA:3.30.1360.120 2 52 1.8E-55 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 GTHT12_RS12735 ad0491671c834ea3cee0faa48022484c 365 Gene3D G3DSA:3.30.1360.120 140 235 1.8E-55 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 GTHT12_RS12735 ad0491671c834ea3cee0faa48022484c 365 Pfam PF01571 Aminomethyltransferase folate-binding domain 10 258 1.5E-98 T 06-07-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal GTHT12_RS12735 ad0491671c834ea3cee0faa48022484c 365 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 2 362 2.4E-145 T 06-07-2017 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 GTHT12_RS12735 ad0491671c834ea3cee0faa48022484c 365 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 267 356 5.3E-28 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 GTHT12_RS11680 46a0017e3e6146ff1ea041b34d8cf431 149 Gene3D G3DSA:3.30.70.141 2 149 7.5E-70 T 06-07-2017 GTHT12_RS11680 46a0017e3e6146ff1ea041b34d8cf431 149 SMART SM00562 2 139 1.0E-96 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 GTHT12_RS11680 46a0017e3e6146ff1ea041b34d8cf431 149 Pfam PF00334 Nucleoside diphosphate kinase 3 136 3.1E-62 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 GTHT12_RS11680 46a0017e3e6146ff1ea041b34d8cf431 149 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 113 121 - T 06-07-2017 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 GTHT12_RS11680 46a0017e3e6146ff1ea041b34d8cf431 149 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 2 137 38.847 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 GTHT12_RS11680 46a0017e3e6146ff1ea041b34d8cf431 149 SUPERFAMILY SSF54919 1 149 6.02E-65 T 06-07-2017 GTHT12_RS11680 46a0017e3e6146ff1ea041b34d8cf431 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 49 68 5.7E-53 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 GTHT12_RS11680 46a0017e3e6146ff1ea041b34d8cf431 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 113 132 5.7E-53 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 GTHT12_RS11680 46a0017e3e6146ff1ea041b34d8cf431 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 5 27 5.7E-53 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 GTHT12_RS11680 46a0017e3e6146ff1ea041b34d8cf431 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 69 86 5.7E-53 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 GTHT12_RS11680 46a0017e3e6146ff1ea041b34d8cf431 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 90 106 5.7E-53 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 GTHT12_RS09640 f17727d94241c2393e1138274f2eba55 303 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 GTHT12_RS09640 f17727d94241c2393e1138274f2eba55 303 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 GTHT12_RS09640 f17727d94241c2393e1138274f2eba55 303 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 300 8.1E-114 T 06-07-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 GTHT12_RS09640 f17727d94241c2393e1138274f2eba55 303 SUPERFAMILY SSF53613 1 300 6.55E-72 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS09640 f17727d94241c2393e1138274f2eba55 303 Gene3D G3DSA:3.40.1190.20 36 301 2.8E-83 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS09640 f17727d94241c2393e1138274f2eba55 303 PIRSF PIRSF000535 1 303 1.0E-90 T 06-07-2017 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 GTHT12_RS09640 f17727d94241c2393e1138274f2eba55 303 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 300 3.3E-114 T 06-07-2017 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 GTHT12_RS09640 f17727d94241c2393e1138274f2eba55 303 Gene3D G3DSA:2.20.150.10 9 35 6.6E-5 T 06-07-2017 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain KEGG: 00052+2.7.1.144|KEGG: 00710+2.7.1.14|MetaCyc: PWY-7077|MetaCyc: PWY-7395 GTHT12_RS09640 f17727d94241c2393e1138274f2eba55 303 Pfam PF00294 pfkB family carbohydrate kinase 13 283 7.7E-58 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB GTHT12_RS14400 2382106ce9e7db948a72f80e89070e3d 267 Hamap MF_00361 NAD kinase [nadK]. 6 267 21.001 T 06-07-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 GTHT12_RS14400 2382106ce9e7db948a72f80e89070e3d 267 Gene3D G3DSA:2.60.200.30 127 244 8.6E-28 T 06-07-2017 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 GTHT12_RS14400 2382106ce9e7db948a72f80e89070e3d 267 Pfam PF01513 ATP-NAD kinase 41 252 6.0E-15 T 06-07-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 GTHT12_RS14400 2382106ce9e7db948a72f80e89070e3d 267 Gene3D G3DSA:3.40.50.10330 37 126 2.0E-11 T 06-07-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 GTHT12_RS14400 2382106ce9e7db948a72f80e89070e3d 267 SUPERFAMILY SSF111331 12 266 7.03E-56 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain GTHT12_RS01610 a062fafef7f35d7fcffcd50bd804dc8b 84 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 3 78 2.7E-32 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GTHT12_RS01610 a062fafef7f35d7fcffcd50bd804dc8b 84 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 80 7.0E-32 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GTHT12_RS01610 a062fafef7f35d7fcffcd50bd804dc8b 84 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 2 80 2.0E-34 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GTHT12_RS01610 a062fafef7f35d7fcffcd50bd804dc8b 84 SUPERFAMILY SSF82697 1 80 3.49E-30 T 06-07-2017 GTHT12_RS01610 a062fafef7f35d7fcffcd50bd804dc8b 84 Gene3D G3DSA:3.30.1280.10 1 80 3.2E-35 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GTHT12_RS01610 a062fafef7f35d7fcffcd50bd804dc8b 84 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 78 22.402 T 06-07-2017 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GTHT12_RS05465 d29dc462d588ebdf0b446ad5fc07d6ef 216 Pfam PF08924 Domain of unknown function (DUF1906) 30 132 2.5E-13 T 06-07-2017 IPR015020 Protein of unknown function DUF1906 GTHT12_RS05465 d29dc462d588ebdf0b446ad5fc07d6ef 216 SUPERFAMILY SSF51445 5 214 3.58E-61 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS05465 d29dc462d588ebdf0b446ad5fc07d6ef 216 Gene3D G3DSA:3.20.20.80 5 214 1.0E-69 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS15875 b39408e83ba2b2fcbcb619337eb42828 499 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 102 117 - T 06-07-2017 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 GTHT12_RS15875 b39408e83ba2b2fcbcb619337eb42828 499 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 181 196 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site GTHT12_RS15875 b39408e83ba2b2fcbcb619337eb42828 499 Pfam PF00135 Carboxylesterase family 5 484 7.3E-120 T 06-07-2017 IPR002018 Carboxylesterase, type B GTHT12_RS15875 b39408e83ba2b2fcbcb619337eb42828 499 Gene3D G3DSA:3.40.50.1820 3 496 4.1E-153 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS15875 b39408e83ba2b2fcbcb619337eb42828 499 SUPERFAMILY SSF53474 3 497 4.87E-132 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS17020 993c745c325ed5c415828eefbc86b7c1 279 SUPERFAMILY SSF53098 134 276 1.09E-29 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS17020 993c745c325ed5c415828eefbc86b7c1 279 Pfam PF00665 Integrase core domain 133 252 2.8E-25 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS17020 993c745c325ed5c415828eefbc86b7c1 279 Pfam PF13276 HTH-like domain 72 118 8.7E-12 T 06-07-2017 IPR025948 HTH-like domain GTHT12_RS17020 993c745c325ed5c415828eefbc86b7c1 279 Gene3D G3DSA:3.30.420.10 128 277 9.9E-32 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS01720 6701768dc7d364733db4f81a54de30da 485 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 477 99.003 T 06-07-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 GTHT12_RS01720 6701768dc7d364733db4f81a54de30da 485 Gene3D G3DSA:3.90.1300.10 3 483 1.5E-193 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 GTHT12_RS01720 6701768dc7d364733db4f81a54de30da 485 SUPERFAMILY SSF75304 1 483 7.06E-179 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 GTHT12_RS01720 6701768dc7d364733db4f81a54de30da 485 Pfam PF01425 Amidase 24 465 1.1E-170 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 GTHT12_RS01720 6701768dc7d364733db4f81a54de30da 485 ProSitePatterns PS00571 Amidases signature. 152 183 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 GTHT12_RS01720 6701768dc7d364733db4f81a54de30da 485 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 477 8.7E-212 T 06-07-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 GTHT12_RS13865 e9dcb9b5e324070bfd28590a43644fac 471 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 3 464 5.5E-251 T 06-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 GTHT12_RS13865 e9dcb9b5e324070bfd28590a43644fac 471 ProSitePatterns PS01244 Aconitase family signature 2. 399 412 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 GTHT12_RS13865 e9dcb9b5e324070bfd28590a43644fac 471 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 466 60.645 T 06-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 GTHT12_RS13865 e9dcb9b5e324070bfd28590a43644fac 471 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 GTHT12_RS13865 e9dcb9b5e324070bfd28590a43644fac 471 PRINTS PR00415 Aconitase family signature 195 208 1.7E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS13865 e9dcb9b5e324070bfd28590a43644fac 471 PRINTS PR00415 Aconitase family signature 133 148 1.7E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS13865 e9dcb9b5e324070bfd28590a43644fac 471 PRINTS PR00415 Aconitase family signature 209 222 1.7E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS13865 e9dcb9b5e324070bfd28590a43644fac 471 PRINTS PR00415 Aconitase family signature 82 95 1.7E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS13865 e9dcb9b5e324070bfd28590a43644fac 471 PRINTS PR00415 Aconitase family signature 343 354 1.7E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS13865 e9dcb9b5e324070bfd28590a43644fac 471 PRINTS PR00415 Aconitase family signature 108 116 1.7E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS13865 e9dcb9b5e324070bfd28590a43644fac 471 PRINTS PR00415 Aconitase family signature 399 412 1.7E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS13865 e9dcb9b5e324070bfd28590a43644fac 471 PRINTS PR00415 Aconitase family signature 119 132 1.7E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS13865 e9dcb9b5e324070bfd28590a43644fac 471 PRINTS PR00415 Aconitase family signature 286 300 1.7E-47 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS13865 e9dcb9b5e324070bfd28590a43644fac 471 Gene3D G3DSA:3.40.1060.10 155 289 2.7E-41 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS13865 e9dcb9b5e324070bfd28590a43644fac 471 Gene3D G3DSA:3.30.499.10 333 466 5.4E-62 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS13865 e9dcb9b5e324070bfd28590a43644fac 471 Pfam PF00330 Aconitase family (aconitate hydratase) 8 457 3.4E-161 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS13865 e9dcb9b5e324070bfd28590a43644fac 471 Gene3D G3DSA:3.30.499.10 2 154 4.2E-24 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS13865 e9dcb9b5e324070bfd28590a43644fac 471 SUPERFAMILY SSF53732 2 466 4.97E-176 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS09830 4ccc191c6eb1db704993d63d6611a690 213 Pfam PF04854 Protein of unknown function, DUF624 20 97 2.7E-24 T 06-07-2017 IPR006938 Protein of unknown function DUF624 GTHT12_RS13850 0e3d3bb13cbb2ab7d5f761c904b6b664 428 SUPERFAMILY SSF109998 250 426 1.44E-45 T 06-07-2017 IPR027304 Trigger factor/SurA domain GTHT12_RS13850 0e3d3bb13cbb2ab7d5f761c904b6b664 428 PIRSF PIRSF003095 1 428 4.4E-143 T 06-07-2017 IPR005215 Trigger factor GO:0015031 GTHT12_RS13850 0e3d3bb13cbb2ab7d5f761c904b6b664 428 TIGRFAM TIGR00115 tig: trigger factor 12 421 6.8E-149 T 06-07-2017 IPR005215 Trigger factor GO:0015031 GTHT12_RS13850 0e3d3bb13cbb2ab7d5f761c904b6b664 428 Pfam PF05697 Bacterial trigger factor protein (TF) 1 145 1.6E-45 T 06-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 GTHT12_RS13850 0e3d3bb13cbb2ab7d5f761c904b6b664 428 Gene3D G3DSA:1.10.3120.10 218 399 2.3E-66 T 06-07-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 GTHT12_RS13850 0e3d3bb13cbb2ab7d5f761c904b6b664 428 SUPERFAMILY SSF54534 89 243 1.37E-40 T 06-07-2017 GTHT12_RS13850 0e3d3bb13cbb2ab7d5f761c904b6b664 428 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 160 239 9.1E-16 T 06-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 GTHT12_RS13850 0e3d3bb13cbb2ab7d5f761c904b6b664 428 Gene3D G3DSA:3.10.50.40 151 217 2.6E-9 T 06-07-2017 GTHT12_RS13850 0e3d3bb13cbb2ab7d5f761c904b6b664 428 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 422 3.3E-48 T 06-07-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 GTHT12_RS13850 0e3d3bb13cbb2ab7d5f761c904b6b664 428 Hamap MF_00303 Trigger factor [tig]. 1 427 24.494 T 06-07-2017 IPR005215 Trigger factor GO:0015031 GTHT12_RS13850 0e3d3bb13cbb2ab7d5f761c904b6b664 428 Gene3D G3DSA:3.30.70.1050 1 119 1.3E-38 T 06-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 GTHT12_RS13850 0e3d3bb13cbb2ab7d5f761c904b6b664 428 SUPERFAMILY SSF102735 1 130 1.96E-40 T 06-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 GTHT12_RS18675 5939b97e8f01ddb4007299fbb67b6ff6 382 Pfam PF01051 Initiator Replication protein 12 225 7.9E-62 T 06-07-2017 IPR000525 Initiator Rep protein GO:0003887|GO:0005727|GO:0006270 GTHT12_RS18675 5939b97e8f01ddb4007299fbb67b6ff6 382 Gene3D G3DSA:1.10.10.10 142 228 7.6E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS18675 5939b97e8f01ddb4007299fbb67b6ff6 382 SUPERFAMILY SSF46785 129 228 3.13E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS18675 5939b97e8f01ddb4007299fbb67b6ff6 382 SUPERFAMILY SSF46785 17 138 4.73E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS18675 5939b97e8f01ddb4007299fbb67b6ff6 382 Gene3D G3DSA:1.10.10.10 9 141 3.7E-41 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS13435 57ce02b6c6d8e5e455e026d0c455d183 431 SUPERFAMILY SSF52540 3 214 1.9E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13435 57ce02b6c6d8e5e455e026d0c455d183 431 Gene3D G3DSA:1.10.3710.10 335 427 7.7E-29 T 06-07-2017 GTHT12_RS13435 57ce02b6c6d8e5e455e026d0c455d183 431 Pfam PF16193 AAA C-terminal domain 177 255 1.1E-17 T 06-07-2017 IPR032423 AAA ATPase, C-terminal domain GTHT12_RS13435 57ce02b6c6d8e5e455e026d0c455d183 431 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 378 397 8.8E-5 T 06-07-2017 GTHT12_RS13435 57ce02b6c6d8e5e455e026d0c455d183 431 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 49 68 8.8E-5 T 06-07-2017 GTHT12_RS13435 57ce02b6c6d8e5e455e026d0c455d183 431 SMART SM00382 41 153 8.9E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS13435 57ce02b6c6d8e5e455e026d0c455d183 431 Gene3D G3DSA:1.20.272.10 237 334 2.4E-37 T 06-07-2017 GTHT12_RS13435 57ce02b6c6d8e5e455e026d0c455d183 431 Gene3D G3DSA:1.10.8.60 141 213 4.8E-11 T 06-07-2017 GTHT12_RS13435 57ce02b6c6d8e5e455e026d0c455d183 431 Pfam PF12002 MgsA AAA+ ATPase C terminal 256 420 2.5E-65 T 06-07-2017 IPR021886 MgsA AAA+ ATPase C-terminal GTHT12_RS13435 57ce02b6c6d8e5e455e026d0c455d183 431 Gene3D G3DSA:3.40.50.300 5 140 2.6E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13435 57ce02b6c6d8e5e455e026d0c455d183 431 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 45 151 1.7E-17 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 GTHT12_RS13435 57ce02b6c6d8e5e455e026d0c455d183 431 SUPERFAMILY SSF48019 241 424 5.27E-69 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 GTHT12_RS13570 197f8ba7e4c69a37cdffc11328382dac 314 SUPERFAMILY SSF56112 38 294 2.97E-20 T 06-07-2017 IPR011009 Protein kinase-like domain GTHT12_RS13570 197f8ba7e4c69a37cdffc11328382dac 314 Gene3D G3DSA:3.90.1200.10 113 287 1.5E-12 T 06-07-2017 GTHT12_RS13570 197f8ba7e4c69a37cdffc11328382dac 314 Pfam PF01636 Phosphotransferase enzyme family 40 244 2.0E-10 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase GTHT12_RS13940 a9d29a213ef84c2abbf72b832442099d 253 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 155 166 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GTHT12_RS13940 a9d29a213ef84c2abbf72b832442099d 253 SUPERFAMILY SSF54292 4 112 3.05E-23 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 GTHT12_RS13940 a9d29a213ef84c2abbf72b832442099d 253 Gene3D G3DSA:3.10.20.30 2 112 2.1E-27 T 06-07-2017 IPR012675 Beta-grasp domain GTHT12_RS13940 a9d29a213ef84c2abbf72b832442099d 253 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 10 117 2.2E-28 T 06-07-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 GTHT12_RS13940 a9d29a213ef84c2abbf72b832442099d 253 SUPERFAMILY SSF46548 114 239 1.92E-26 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 GTHT12_RS13940 a9d29a213ef84c2abbf72b832442099d 253 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 12 234 6.8E-40 T 06-07-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 GTHT12_RS13940 a9d29a213ef84c2abbf72b832442099d 253 Gene3D G3DSA:1.10.1060.10 113 240 8.8E-31 T 06-07-2017 GTHT12_RS13940 a9d29a213ef84c2abbf72b832442099d 253 Pfam PF13183 4Fe-4S dicluster domain 151 226 9.2E-9 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain GTHT12_RS04895 36213a1c494b45c1779f0b7ec10bca05 304 Pfam PF01565 FAD binding domain 39 167 3.2E-26 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 GTHT12_RS04895 36213a1c494b45c1779f0b7ec10bca05 304 SUPERFAMILY SSF56176 6 197 1.27E-47 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 GTHT12_RS04895 36213a1c494b45c1779f0b7ec10bca05 304 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 202 301 7.2E-30 T 06-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS04895 36213a1c494b45c1779f0b7ec10bca05 304 Gene3D G3DSA:3.90.78.10 230 303 1.5E-32 T 06-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS04895 36213a1c494b45c1779f0b7ec10bca05 304 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 304 92.513 T 06-07-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS04895 36213a1c494b45c1779f0b7ec10bca05 304 SUPERFAMILY SSF56194 198 303 1.7E-37 T 06-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS04895 36213a1c494b45c1779f0b7ec10bca05 304 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 26 302 3.4E-72 T 06-07-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS04895 36213a1c494b45c1779f0b7ec10bca05 304 Gene3D G3DSA:3.30.43.10 3 90 5.8E-30 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 GTHT12_RS04895 36213a1c494b45c1779f0b7ec10bca05 304 Gene3D G3DSA:3.30.465.10 91 229 5.0E-48 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 GTHT12_RS15815 63f6d493b2b18f942558ca2da23d28b1 327 SUPERFAMILY SSF54593 5 282 2.28E-44 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GTHT12_RS15815 63f6d493b2b18f942558ca2da23d28b1 327 Gene3D G3DSA:3.10.180.10 3 148 3.0E-31 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GTHT12_RS15815 63f6d493b2b18f942558ca2da23d28b1 327 TIGRFAM TIGR02295 HpaD: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 5 300 4.8E-134 T 06-07-2017 IPR011981 3,4-dihydroxyphenylacetate 2,3-dioxygenase HpaD GTHT12_RS15815 63f6d493b2b18f942558ca2da23d28b1 327 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 237 258 - T 06-07-2017 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 GTHT12_RS15815 63f6d493b2b18f942558ca2da23d28b1 327 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 142 259 5.9E-18 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain GTHT12_RS15815 63f6d493b2b18f942558ca2da23d28b1 327 Gene3D G3DSA:3.10.180.10 149 280 1.5E-43 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GTHT12_RS09925 75ef3566489efdc98788bb2657b1a623 263 Pfam PF00072 Response regulator receiver domain 6 119 1.0E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS09925 75ef3566489efdc98788bb2657b1a623 263 SUPERFAMILY SSF46689 206 256 3.63E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS09925 75ef3566489efdc98788bb2657b1a623 263 Gene3D G3DSA:1.10.10.60 207 257 7.1E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS09925 75ef3566489efdc98788bb2657b1a623 263 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 222 237 1.0E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 GTHT12_RS09925 75ef3566489efdc98788bb2657b1a623 263 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 237 253 1.0E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 GTHT12_RS09925 75ef3566489efdc98788bb2657b1a623 263 SMART SM00448 4 118 3.9E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS09925 75ef3566489efdc98788bb2657b1a623 263 SUPERFAMILY SSF46689 155 204 8.33E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS09925 75ef3566489efdc98788bb2657b1a623 263 SMART SM00342 170 253 1.2E-33 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 GTHT12_RS09925 75ef3566489efdc98788bb2657b1a623 263 Pfam PF12833 Helix-turn-helix domain 176 255 1.8E-24 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 GTHT12_RS09925 75ef3566489efdc98788bb2657b1a623 263 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 207 249 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 GTHT12_RS09925 75ef3566489efdc98788bb2657b1a623 263 Gene3D G3DSA:1.10.10.60 151 206 8.3E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS09925 75ef3566489efdc98788bb2657b1a623 263 Gene3D G3DSA:3.40.50.2300 3 130 4.2E-34 T 06-07-2017 GTHT12_RS09925 75ef3566489efdc98788bb2657b1a623 263 SUPERFAMILY SSF52172 3 130 1.71E-35 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS06625 8231ffff9367406592346ecccfe424ed 556 SMART SM00849 23 215 4.0E-21 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS06625 8231ffff9367406592346ecccfe424ed 556 Gene3D G3DSA:3.60.15.10 9 257 2.2E-70 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS06625 8231ffff9367406592346ecccfe424ed 556 Pfam PF00753 Metallo-beta-lactamase superfamily 21 164 2.8E-9 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS06625 8231ffff9367406592346ecccfe424ed 556 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 365 393 - T 06-07-2017 IPR001587 Ribonuclease J, conserved site GTHT12_RS06625 8231ffff9367406592346ecccfe424ed 556 Hamap MF_01491 Ribonuclease J [rnj]. 6 556 44.711 T 06-07-2017 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 GTHT12_RS06625 8231ffff9367406592346ecccfe424ed 556 PIRSF PIRSF004803 2 556 7.0E-222 T 06-07-2017 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 GTHT12_RS06625 8231ffff9367406592346ecccfe424ed 556 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 11 554 1.7E-200 T 06-07-2017 IPR004613 Ribonuclease J GO:0003723|GO:0046872 GTHT12_RS06625 8231ffff9367406592346ecccfe424ed 556 SUPERFAMILY SSF56281 11 425 1.78E-89 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS06625 8231ffff9367406592346ecccfe424ed 556 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 356 408 2.3E-13 T 06-07-2017 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain GTHT12_RS09665 8550c32ee13115a223b07af28d331e41 433 SMART SM00710 276 297 1400.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat GTHT12_RS09665 8550c32ee13115a223b07af28d331e41 433 SMART SM00710 254 275 16.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat GTHT12_RS09665 8550c32ee13115a223b07af28d331e41 433 SMART SM00710 132 161 1300.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat GTHT12_RS09665 8550c32ee13115a223b07af28d331e41 433 SMART SM00710 184 205 2200.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat GTHT12_RS09665 8550c32ee13115a223b07af28d331e41 433 SMART SM00710 110 131 600.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat GTHT12_RS09665 8550c32ee13115a223b07af28d331e41 433 SMART SM00710 162 183 10.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat GTHT12_RS09665 8550c32ee13115a223b07af28d331e41 433 SMART SM00710 206 227 980.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat GTHT12_RS09665 8550c32ee13115a223b07af28d331e41 433 SMART SM00710 80 109 480.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat GTHT12_RS09665 8550c32ee13115a223b07af28d331e41 433 Gene3D G3DSA:2.160.20.10 24 317 9.3E-31 T 06-07-2017 IPR012334 Pectin lyase fold GTHT12_RS09665 8550c32ee13115a223b07af28d331e41 433 SMART SM00722 188 325 33.0 T 06-07-2017 IPR006633 Carbohydrate-binding/sugar hydrolysis domain GTHT12_RS09665 8550c32ee13115a223b07af28d331e41 433 SMART SM00722 33 182 2.8E-5 T 06-07-2017 IPR006633 Carbohydrate-binding/sugar hydrolysis domain GTHT12_RS09665 8550c32ee13115a223b07af28d331e41 433 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 156 198 6.5E-7 T 06-07-2017 IPR022441 Parallel beta-helix repeat-2 GTHT12_RS09665 8550c32ee13115a223b07af28d331e41 433 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 270 300 1.1E-4 T 06-07-2017 IPR022441 Parallel beta-helix repeat-2 GTHT12_RS09665 8550c32ee13115a223b07af28d331e41 433 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 178 219 1.5E-5 T 06-07-2017 IPR022441 Parallel beta-helix repeat-2 GTHT12_RS09665 8550c32ee13115a223b07af28d331e41 433 SUPERFAMILY SSF51126 21 392 2.91E-59 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor GTHT12_RS09665 8550c32ee13115a223b07af28d331e41 433 TIGRFAM TIGR04247 NosD_copper_fam: nitrous oxide reductase family maturation protein NosD 27 405 4.6E-123 T 06-07-2017 IPR026464 Nitrous oxide reductase family maturation protein NosD GTHT12_RS09665 8550c32ee13115a223b07af28d331e41 433 Pfam PF05048 Periplasmic copper-binding protein (NosD) 149 360 9.9E-39 T 06-07-2017 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain GTHT12_RS02310 5afed47cf87e39bb43117ab12c72958e 775 Gene3D G3DSA:3.90.1170.50 3 108 5.8E-43 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead GTHT12_RS02310 5afed47cf87e39bb43117ab12c72958e 775 SUPERFAMILY SSF56003 112 766 2.09E-157 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 GTHT12_RS02310 5afed47cf87e39bb43117ab12c72958e 775 Gene3D G3DSA:3.30.365.10 109 176 3.9E-33 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 GTHT12_RS02310 5afed47cf87e39bb43117ab12c72958e 775 Gene3D G3DSA:3.30.365.10 285 359 3.9E-33 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 GTHT12_RS02310 5afed47cf87e39bb43117ab12c72958e 775 Gene3D G3DSA:3.30.365.10 443 578 1.5E-35 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 GTHT12_RS02310 5afed47cf87e39bb43117ab12c72958e 775 Gene3D G3DSA:3.30.365.10 177 282 5.9E-24 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 GTHT12_RS02310 5afed47cf87e39bb43117ab12c72958e 775 SMART SM01008 17 120 3.6E-49 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead GTHT12_RS02310 5afed47cf87e39bb43117ab12c72958e 775 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 17 120 2.7E-28 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead GTHT12_RS02310 5afed47cf87e39bb43117ab12c72958e 775 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 154 708 3.4E-133 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 GTHT12_RS02310 5afed47cf87e39bb43117ab12c72958e 775 Gene3D G3DSA:3.30.365.10 579 767 3.9E-44 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 GTHT12_RS02310 5afed47cf87e39bb43117ab12c72958e 775 SUPERFAMILY SSF54665 3 141 2.22E-46 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead GTHT12_RS06950 210ef9d5a5dbde91fa246114a31d6115 894 Pfam PF06971 Putative DNA-binding protein N-terminus 1 43 1.1E-4 T 06-07-2017 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 GTHT12_RS06950 210ef9d5a5dbde91fa246114a31d6115 894 Gene3D G3DSA:1.10.10.10 6 70 4.6E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS06950 210ef9d5a5dbde91fa246114a31d6115 894 SUPERFAMILY SSF63520 432 527 1.7E-20 T 06-07-2017 IPR011608 PRD domain GO:0006355 GTHT12_RS06950 210ef9d5a5dbde91fa246114a31d6115 894 SUPERFAMILY SSF53062 540 661 9.07E-21 T 06-07-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 GTHT12_RS06950 210ef9d5a5dbde91fa246114a31d6115 894 Gene3D G3DSA:3.40.50.510 537 664 2.0E-44 T 06-07-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 GTHT12_RS06950 210ef9d5a5dbde91fa246114a31d6115 894 Gene3D G3DSA:3.40.50.300 73 250 2.5E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06950 210ef9d5a5dbde91fa246114a31d6115 894 SMART SM00382 99 248 3.0E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS06950 210ef9d5a5dbde91fa246114a31d6115 894 Pfam PF00158 Sigma-54 interaction domain 77 240 9.9E-46 T 06-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 GTHT12_RS06950 210ef9d5a5dbde91fa246114a31d6115 894 Pfam PF00874 PRD domain 443 526 6.3E-17 T 06-07-2017 IPR011608 PRD domain GO:0006355 GTHT12_RS06950 210ef9d5a5dbde91fa246114a31d6115 894 Pfam PF00874 PRD domain 807 887 4.3E-6 T 06-07-2017 IPR011608 PRD domain GO:0006355 GTHT12_RS06950 210ef9d5a5dbde91fa246114a31d6115 894 SUPERFAMILY SSF46785 17 64 5.81E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS06950 210ef9d5a5dbde91fa246114a31d6115 894 SUPERFAMILY SSF52540 88 317 3.94E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06950 210ef9d5a5dbde91fa246114a31d6115 894 Gene3D G3DSA:1.10.1790.10 433 528 8.8E-21 T 06-07-2017 IPR011608 PRD domain GO:0006355 GTHT12_RS06950 210ef9d5a5dbde91fa246114a31d6115 894 Gene3D G3DSA:1.10.1790.10 791 889 1.1E-10 T 06-07-2017 IPR011608 PRD domain GO:0006355 GTHT12_RS06950 210ef9d5a5dbde91fa246114a31d6115 894 SUPERFAMILY SSF63520 785 892 4.58E-12 T 06-07-2017 IPR011608 PRD domain GO:0006355 GTHT12_RS06950 210ef9d5a5dbde91fa246114a31d6115 894 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 103 116 - T 06-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 GTHT12_RS06950 210ef9d5a5dbde91fa246114a31d6115 894 Pfam PF03610 PTS system fructose IIA component 542 654 1.4E-10 T 06-07-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 GTHT12_RS06675 0c1ea26b24f035482b0d1cc30f9daf7c 432 Gene3D G3DSA:3.30.830.10 5 229 9.4E-83 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 GTHT12_RS06675 0c1ea26b24f035482b0d1cc30f9daf7c 432 Pfam PF05193 Peptidase M16 inactive domain 183 356 2.5E-26 T 06-07-2017 IPR007863 Peptidase M16, C-terminal GTHT12_RS06675 0c1ea26b24f035482b0d1cc30f9daf7c 432 Gene3D G3DSA:3.30.830.10 246 410 6.5E-33 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 GTHT12_RS06675 0c1ea26b24f035482b0d1cc30f9daf7c 432 SUPERFAMILY SSF63411 245 413 3.33E-35 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 GTHT12_RS06675 0c1ea26b24f035482b0d1cc30f9daf7c 432 SUPERFAMILY SSF63411 12 230 2.79E-28 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 GTHT12_RS04970 a9c38715eed796aad9b5393162589e97 698 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 6 199 1.6E-55 T 06-07-2017 IPR032856 Putative glycogen debranching enzyme, N-terminal GTHT12_RS04970 a9c38715eed796aad9b5393162589e97 698 Pfam PF06202 Amylo-alpha-1,6-glucosidase 269 625 8.8E-17 T 06-07-2017 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25+3.2.1.33|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 GTHT12_RS04970 a9c38715eed796aad9b5393162589e97 698 SUPERFAMILY SSF48208 217 681 6.5E-90 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 GTHT12_RS04970 a9c38715eed796aad9b5393162589e97 698 Gene3D G3DSA:1.50.10.10 438 490 9.1E-4 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 GTHT12_RS18130 a811896f89b7389bd9560bcb2b65662b 428 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 06-07-2017 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 GTHT12_RS18130 a811896f89b7389bd9560bcb2b65662b 428 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 428 213.556 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 GTHT12_RS18130 a811896f89b7389bd9560bcb2b65662b 428 SUPERFAMILY SSF52540 1 426 1.02E-177 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18130 a811896f89b7389bd9560bcb2b65662b 428 Pfam PF00709 Adenylosuccinate synthetase 4 420 1.0E-182 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 GTHT12_RS18130 a811896f89b7389bd9560bcb2b65662b 428 Gene3D G3DSA:3.90.170.10 265 423 1.7E-68 T 06-07-2017 GTHT12_RS18130 a811896f89b7389bd9560bcb2b65662b 428 Gene3D G3DSA:1.10.300.10 100 194 5.2E-37 T 06-07-2017 GTHT12_RS18130 a811896f89b7389bd9560bcb2b65662b 428 Gene3D G3DSA:3.40.440.10 1 93 2.3E-73 T 06-07-2017 GTHT12_RS18130 a811896f89b7389bd9560bcb2b65662b 428 Gene3D G3DSA:3.40.440.10 195 264 2.3E-73 T 06-07-2017 GTHT12_RS18130 a811896f89b7389bd9560bcb2b65662b 428 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 427 2.7E-197 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 GTHT12_RS18130 a811896f89b7389bd9560bcb2b65662b 428 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 06-07-2017 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 GTHT12_RS18130 a811896f89b7389bd9560bcb2b65662b 428 SMART SM00788 3 422 2.0E-295 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 GTHT12_RS10150 7ae14187ba32eb56435423c0a94f15d0 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 1.0E-12 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 GTHT12_RS10150 7ae14187ba32eb56435423c0a94f15d0 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 1.0E-12 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 GTHT12_RS10150 7ae14187ba32eb56435423c0a94f15d0 148 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 1.0E-12 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 GTHT12_RS10150 7ae14187ba32eb56435423c0a94f15d0 148 Gene3D G3DSA:1.10.10.10 1 52 5.0E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS10150 7ae14187ba32eb56435423c0a94f15d0 148 SMART SM00344 5 110 3.0E-25 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 GTHT12_RS10150 7ae14187ba32eb56435423c0a94f15d0 148 Pfam PF01037 Lrp/AsnC ligand binding domain 72 139 3.5E-9 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain GTHT12_RS10150 7ae14187ba32eb56435423c0a94f15d0 148 SUPERFAMILY SSF46785 3 63 3.33E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS10150 7ae14187ba32eb56435423c0a94f15d0 148 Gene3D G3DSA:3.30.70.920 68 142 3.5E-15 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain GTHT12_RS10150 7ae14187ba32eb56435423c0a94f15d0 148 SUPERFAMILY SSF54909 68 142 1.18E-12 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel GTHT12_RS10150 7ae14187ba32eb56435423c0a94f15d0 148 Pfam PF13404 AsnC-type helix-turn-helix domain 5 45 1.4E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 GTHT12_RS13835 4d66254ce85634f2afcff055afc932e9 780 Gene3D G3DSA:3.40.50.300 311 504 5.3E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13835 4d66254ce85634f2afcff055afc932e9 780 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 574 776 1.2E-97 T 06-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 GTHT12_RS13835 4d66254ce85634f2afcff055afc932e9 780 Gene3D G3DSA:3.30.230.10 594 775 1.7E-72 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GTHT12_RS13835 4d66254ce85634f2afcff055afc932e9 780 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 599 615 1.7E-55 T 06-07-2017 GTHT12_RS13835 4d66254ce85634f2afcff055afc932e9 780 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 730 748 1.7E-55 T 06-07-2017 GTHT12_RS13835 4d66254ce85634f2afcff055afc932e9 780 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 360 379 1.7E-55 T 06-07-2017 GTHT12_RS13835 4d66254ce85634f2afcff055afc932e9 780 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 677 696 1.7E-55 T 06-07-2017 GTHT12_RS13835 4d66254ce85634f2afcff055afc932e9 780 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 707 726 1.7E-55 T 06-07-2017 GTHT12_RS13835 4d66254ce85634f2afcff055afc932e9 780 Gene3D G3DSA:1.10.8.60 505 588 1.5E-33 T 06-07-2017 GTHT12_RS13835 4d66254ce85634f2afcff055afc932e9 780 SMART SM00382 352 499 5.5E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS13835 4d66254ce85634f2afcff055afc932e9 780 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 680 688 - T 06-07-2017 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 GTHT12_RS13835 4d66254ce85634f2afcff055afc932e9 780 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 356 492 1.5E-23 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 GTHT12_RS13835 4d66254ce85634f2afcff055afc932e9 780 PIRSF PIRSF001174 5 779 0.0 T 06-07-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 GTHT12_RS13835 4d66254ce85634f2afcff055afc932e9 780 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 15 205 7.6E-45 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 GTHT12_RS13835 4d66254ce85634f2afcff055afc932e9 780 SUPERFAMILY SSF54211 599 774 2.73E-55 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS13835 4d66254ce85634f2afcff055afc932e9 780 TIGRFAM TIGR00763 lon: endopeptidase La 16 775 0.0 T 06-07-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 GTHT12_RS13835 4d66254ce85634f2afcff055afc932e9 780 SMART SM00464 14 206 6.0E-70 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 GTHT12_RS13835 4d66254ce85634f2afcff055afc932e9 780 SUPERFAMILY SSF52540 316 592 2.23E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13835 4d66254ce85634f2afcff055afc932e9 780 Hamap MF_01973 Lon protease [lon]. 15 776 73.136 T 06-07-2017 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 GTHT12_RS13835 4d66254ce85634f2afcff055afc932e9 780 SUPERFAMILY SSF88697 15 205 8.7E-46 T 06-07-2017 IPR015947 PUA-like domain GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 326 341 - T 06-07-2017 IPR033136 NAD-dependent DNA ligase, conserved site GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 SMART SM00292 591 668 6.2E-17 T 06-07-2017 IPR001357 BRCT domain GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 SUPERFAMILY SSF56091 4 313 1.3E-125 T 06-07-2017 GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 PIRSF PIRSF001604 1 670 2.8E-264 T 06-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 Pfam PF12826 Helix-hairpin-helix motif 504 566 4.1E-23 T 06-07-2017 GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 Pfam PF14520 Helix-hairpin-helix domain 440 493 5.0E-6 T 06-07-2017 GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 Gene3D G3DSA:1.10.150.20 498 578 1.5E-28 T 06-07-2017 GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 SMART SM00532 5 442 4.5E-302 T 06-07-2017 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 402 428 3.1E-10 T 06-07-2017 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 SUPERFAMILY SSF47781 399 578 2.08E-66 T 06-07-2017 IPR010994 RuvA domain 2-like GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 5 313 3.6E-132 T 06-07-2017 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 Gene3D G3DSA:3.40.50.10190 590 667 8.8E-25 T 06-07-2017 IPR001357 BRCT domain GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 317 393 1.7E-34 T 06-07-2017 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 13 660 3.2E-277 T 06-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 Gene3D G3DSA:1.10.150.20 429 497 8.9E-34 T 06-07-2017 GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 114 143 - T 06-07-2017 IPR018239 NAD-dependent DNA ligase, active site GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 SUPERFAMILY SSF52113 590 665 2.33E-19 T 06-07-2017 IPR001357 BRCT domain GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 Gene3D G3DSA:3.30.470.30 118 247 7.4E-50 T 06-07-2017 GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 Gene3D G3DSA:1.10.287.610 2 69 4.4E-29 T 06-07-2017 GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 SUPERFAMILY SSF50249 312 396 2.06E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 Hamap MF_01588 DNA ligase [ligA]. 4 665 54.716 T 06-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 Gene3D G3DSA:2.40.50.140 315 386 4.2E-32 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 SMART SM00278 474 493 0.32 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 SMART SM00278 440 459 5.9 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 SMART SM00278 538 557 0.97 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 GTHT12_RS01685 03dc235e98fe641fc711c270b4ff8fc0 670 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 591 662 3.2E-13 T 06-07-2017 IPR001357 BRCT domain GTHT12_RS05365 e77b05aa0fbfc86b46349c00d835f6dc 573 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 294 313 2.3E-32 T 06-07-2017 GTHT12_RS05365 e77b05aa0fbfc86b46349c00d835f6dc 573 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 501 513 2.3E-32 T 06-07-2017 GTHT12_RS05365 e77b05aa0fbfc86b46349c00d835f6dc 573 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 448 463 2.3E-32 T 06-07-2017 GTHT12_RS05365 e77b05aa0fbfc86b46349c00d835f6dc 573 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 465 480 2.3E-32 T 06-07-2017 GTHT12_RS05365 e77b05aa0fbfc86b46349c00d835f6dc 573 SUPERFAMILY SSF47831 26 144 4.32E-38 T 06-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 GTHT12_RS05365 e77b05aa0fbfc86b46349c00d835f6dc 573 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 567 1.2E-253 T 06-07-2017 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 GTHT12_RS05365 e77b05aa0fbfc86b46349c00d835f6dc 573 Gene3D G3DSA:3.50.30.10 134 256 2.0E-45 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 GTHT12_RS05365 e77b05aa0fbfc86b46349c00d835f6dc 573 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 127 4.2E-34 T 06-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 GTHT12_RS05365 e77b05aa0fbfc86b46349c00d835f6dc 573 Gene3D G3DSA:3.20.20.60 257 569 5.5E-118 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GTHT12_RS05365 e77b05aa0fbfc86b46349c00d835f6dc 573 Gene3D G3DSA:1.10.274.10 25 133 4.4E-41 T 06-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 GTHT12_RS05365 e77b05aa0fbfc86b46349c00d835f6dc 573 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 185 196 - T 06-07-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 GTHT12_RS05365 e77b05aa0fbfc86b46349c00d835f6dc 573 SUPERFAMILY SSF52009 126 247 4.58E-38 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 GTHT12_RS05365 e77b05aa0fbfc86b46349c00d835f6dc 573 PIRSF PIRSF000732 1 572 1.0E-231 T 06-07-2017 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 GTHT12_RS05365 e77b05aa0fbfc86b46349c00d835f6dc 573 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 448 466 - T 06-07-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 GTHT12_RS05365 e77b05aa0fbfc86b46349c00d835f6dc 573 Pfam PF00391 PEP-utilising enzyme, mobile domain 154 226 2.7E-23 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 GTHT12_RS05365 e77b05aa0fbfc86b46349c00d835f6dc 573 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 251 541 3.9E-132 T 06-07-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 GTHT12_RS05365 e77b05aa0fbfc86b46349c00d835f6dc 573 SUPERFAMILY SSF51621 250 548 2.12E-116 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GTHT12_RS04640 f0fcaba05df1c2c8a9f5ca7dd6f5dbb4 356 SUPERFAMILY SSF56349 68 355 1.27E-70 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 GTHT12_RS04640 f0fcaba05df1c2c8a9f5ca7dd6f5dbb4 356 Pfam PF00589 Phage integrase family 176 355 4.8E-28 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS04640 f0fcaba05df1c2c8a9f5ca7dd6f5dbb4 356 Pfam PF14657 AP2-like DNA-binding integrase domain 15 58 6.2E-11 T 06-07-2017 IPR028259 AP2-like integrase, N-terminal domain GTHT12_RS04640 f0fcaba05df1c2c8a9f5ca7dd6f5dbb4 356 Gene3D G3DSA:1.10.443.10 175 356 1.4E-44 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS04640 f0fcaba05df1c2c8a9f5ca7dd6f5dbb4 356 Gene3D G3DSA:1.10.150.130 68 168 6.4E-18 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal GTHT12_RS04640 f0fcaba05df1c2c8a9f5ca7dd6f5dbb4 356 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 68 122 1.1E-12 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 GTHT12_RS17450 d4ba94884428dd897ef7c274e3499328 366 SUPERFAMILY SSF56762 16 365 3.27E-123 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17450 d4ba94884428dd897ef7c274e3499328 366 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 1 366 46.981 T 06-07-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17450 d4ba94884428dd897ef7c274e3499328 366 Gene3D G3DSA:1.10.645.10 4 358 1.1E-62 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17450 d4ba94884428dd897ef7c274e3499328 366 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 290 1.9E-68 T 06-07-2017 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17450 d4ba94884428dd897ef7c274e3499328 366 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 292 365 9.2E-27 T 06-07-2017 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS15660 75e66251104a709741d1054ff6b7e8fa 594 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 147 240 3.6E-22 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 GTHT12_RS15660 75e66251104a709741d1054ff6b7e8fa 594 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 31 143 1.6E-29 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS15660 75e66251104a709741d1054ff6b7e8fa 594 SUPERFAMILY SSF47203 257 422 6.44E-45 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS15660 75e66251104a709741d1054ff6b7e8fa 594 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 149 161 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 GTHT12_RS15660 75e66251104a709741d1054ff6b7e8fa 594 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 252 415 1.2E-34 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS15660 75e66251104a709741d1054ff6b7e8fa 594 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 378 397 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 GTHT12_RS15660 75e66251104a709741d1054ff6b7e8fa 594 Gene3D G3DSA:1.10.540.10 13 145 1.2E-35 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS15660 75e66251104a709741d1054ff6b7e8fa 594 Gene3D G3DSA:2.40.110.10 146 240 4.5E-35 T 06-07-2017 GTHT12_RS15660 75e66251104a709741d1054ff6b7e8fa 594 Gene3D G3DSA:1.20.140.10 241 423 2.3E-57 T 06-07-2017 GTHT12_RS15660 75e66251104a709741d1054ff6b7e8fa 594 SUPERFAMILY SSF56645 24 263 8.38E-74 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 GTHT12_RS12710 74cc5e703315e1438c9c046acf124655 124 Pfam PF00581 Rhodanese-like domain 39 117 7.0E-20 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS12710 74cc5e703315e1438c9c046acf124655 124 SMART SM00450 27 122 1.1E-28 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS12710 74cc5e703315e1438c9c046acf124655 124 SUPERFAMILY SSF52821 6 118 1.1E-35 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS12710 74cc5e703315e1438c9c046acf124655 124 Gene3D G3DSA:3.40.250.10 14 118 8.9E-33 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS14200 24c8b64a8768c1fa1e6681668e42d8e0 274 Gene3D G3DSA:1.10.8.50 135 274 1.3E-53 T 06-07-2017 GTHT12_RS14200 24c8b64a8768c1fa1e6681668e42d8e0 274 SUPERFAMILY SSF81624 2 139 5.63E-44 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 GTHT12_RS14200 24c8b64a8768c1fa1e6681668e42d8e0 274 Pfam PF06827 Zinc finger found in FPG and IleRS 246 273 2.5E-13 T 06-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 GTHT12_RS14200 24c8b64a8768c1fa1e6681668e42d8e0 274 SUPERFAMILY SSF57716 223 273 1.22E-19 T 06-07-2017 GTHT12_RS14200 24c8b64a8768c1fa1e6681668e42d8e0 274 SMART SM01232 134 226 5.6E-46 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 GTHT12_RS14200 24c8b64a8768c1fa1e6681668e42d8e0 274 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 117 1.7E-33 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 GTHT12_RS14200 24c8b64a8768c1fa1e6681668e42d8e0 274 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 273 4.0E-106 T 06-07-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 GTHT12_RS14200 24c8b64a8768c1fa1e6681668e42d8e0 274 Gene3D G3DSA:3.20.190.10 2 134 1.5E-38 T 06-07-2017 GTHT12_RS14200 24c8b64a8768c1fa1e6681668e42d8e0 274 ProSitePatterns PS01242 Zinc finger FPG-type signature. 249 273 - T 06-07-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 GTHT12_RS14200 24c8b64a8768c1fa1e6681668e42d8e0 274 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 134 224 8.1E-29 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 GTHT12_RS14200 24c8b64a8768c1fa1e6681668e42d8e0 274 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 274 44.256 T 06-07-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 GTHT12_RS14200 24c8b64a8768c1fa1e6681668e42d8e0 274 SUPERFAMILY SSF46946 134 222 4.27E-28 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 GTHT12_RS14200 24c8b64a8768c1fa1e6681668e42d8e0 274 SMART SM00898 2 118 4.0E-50 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 GTHT12_RS06875 7e23a913f5f51f90d11f78b3086dabe9 207 Pfam PF00717 Peptidase S24-like 124 188 2.4E-18 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B GTHT12_RS06875 7e23a913f5f51f90d11f78b3086dabe9 207 Gene3D G3DSA:2.10.109.10 85 205 1.9E-44 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain GTHT12_RS06875 7e23a913f5f51f90d11f78b3086dabe9 207 TIGRFAM TIGR00498 lexA: repressor LexA 1 205 3.8E-81 T 06-07-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 GTHT12_RS06875 7e23a913f5f51f90d11f78b3086dabe9 207 SUPERFAMILY SSF51306 83 204 5.93E-35 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C GTHT12_RS06875 7e23a913f5f51f90d11f78b3086dabe9 207 SUPERFAMILY SSF46785 3 70 3.35E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS06875 7e23a913f5f51f90d11f78b3086dabe9 207 Pfam PF01726 LexA DNA binding domain 1 65 9.9E-30 T 06-07-2017 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 GTHT12_RS06875 7e23a913f5f51f90d11f78b3086dabe9 207 Gene3D G3DSA:1.10.10.10 1 70 2.0E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS06875 7e23a913f5f51f90d11f78b3086dabe9 207 Hamap MF_00015 LexA repressor [lexA]. 3 206 34.991 T 06-07-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 GTHT12_RS06875 7e23a913f5f51f90d11f78b3086dabe9 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 132 143 3.7E-10 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 GTHT12_RS06875 7e23a913f5f51f90d11f78b3086dabe9 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 121 131 3.7E-10 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 GTHT12_RS06875 7e23a913f5f51f90d11f78b3086dabe9 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 161 173 3.7E-10 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 GTHT12_RS10545 30c63fc3d9a1dffd93caecc11694fd37 295 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 5 295 5.0E-118 T 06-07-2017 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 GTHT12_RS10545 30c63fc3d9a1dffd93caecc11694fd37 295 Gene3D G3DSA:3.40.50.10490 2 249 8.1E-86 T 06-07-2017 GTHT12_RS10545 30c63fc3d9a1dffd93caecc11694fd37 295 SUPERFAMILY SSF53697 4 247 3.24E-71 T 06-07-2017 GTHT12_RS10545 30c63fc3d9a1dffd93caecc11694fd37 295 Pfam PF01380 SIS domain 127 207 2.3E-11 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 GTHT12_RS10545 30c63fc3d9a1dffd93caecc11694fd37 295 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 184 201 - T 06-07-2017 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 GTHT12_RS10545 30c63fc3d9a1dffd93caecc11694fd37 295 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 1 294 42.063 T 06-07-2017 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 GTHT12_RS08440 276e5ee8b36a4bffecf199e683841f87 337 Gene3D G3DSA:3.40.50.2300 57 174 2.5E-48 T 06-07-2017 GTHT12_RS08440 276e5ee8b36a4bffecf199e683841f87 337 SUPERFAMILY SSF47413 2 62 2.81E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS08440 276e5ee8b36a4bffecf199e683841f87 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 51 1.7E-18 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS08440 276e5ee8b36a4bffecf199e683841f87 337 Pfam PF13377 Periplasmic binding protein-like domain 171 330 1.1E-33 T 06-07-2017 GTHT12_RS08440 276e5ee8b36a4bffecf199e683841f87 337 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 06-07-2017 GTHT12_RS08440 276e5ee8b36a4bffecf199e683841f87 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 5 15 5.6E-5 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS08440 276e5ee8b36a4bffecf199e683841f87 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 15 25 5.6E-5 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS08440 276e5ee8b36a4bffecf199e683841f87 337 Gene3D G3DSA:3.40.50.2300 175 311 2.9E-42 T 06-07-2017 GTHT12_RS08440 276e5ee8b36a4bffecf199e683841f87 337 SUPERFAMILY SSF53822 64 331 1.58E-74 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS08440 276e5ee8b36a4bffecf199e683841f87 337 SMART SM00354 3 74 7.1E-33 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS08440 276e5ee8b36a4bffecf199e683841f87 337 Gene3D G3DSA:1.10.260.40 4 56 3.2E-25 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS17625 8f31a5baea99433075e9564a3a976fdf 531 SUPERFAMILY SSF52540 1 270 4.25E-129 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17625 8f31a5baea99433075e9564a3a976fdf 531 Gene3D G3DSA:3.40.50.300 1 285 4.5E-144 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17625 8f31a5baea99433075e9564a3a976fdf 531 Pfam PF00117 Glutamine amidotransferase class-I 302 527 3.0E-61 T 06-07-2017 IPR017926 Glutamine amidotransferase GTHT12_RS17625 8f31a5baea99433075e9564a3a976fdf 531 SUPERFAMILY SSF52317 290 530 1.35E-88 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS17625 8f31a5baea99433075e9564a3a976fdf 531 TIGRFAM TIGR00337 PyrG: CTP synthase 1 527 4.5E-269 T 06-07-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 GTHT12_RS17625 8f31a5baea99433075e9564a3a976fdf 531 Hamap MF_01227 CTP synthase [pyrG]. 2 531 53.686 T 06-07-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 GTHT12_RS17625 8f31a5baea99433075e9564a3a976fdf 531 Gene3D G3DSA:3.40.50.880 289 530 1.3E-105 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS17625 8f31a5baea99433075e9564a3a976fdf 531 Pfam PF06418 CTP synthase N-terminus 3 267 3.2E-133 T 06-07-2017 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 GTHT12_RS14220 0e167ad883e3c095bebfed41b4acd3ba 155 Pfam PF01575 MaoC like domain 16 125 1.5E-8 T 06-07-2017 IPR002539 MaoC-like domain GTHT12_RS14220 0e167ad883e3c095bebfed41b4acd3ba 155 SUPERFAMILY SSF54637 7 141 4.27E-24 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS14220 0e167ad883e3c095bebfed41b4acd3ba 155 Gene3D G3DSA:3.10.129.10 11 138 1.9E-26 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS06810 b15d6b6cd44d8acde6fd356373ab57ec 524 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 503 2.8E-21 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain GTHT12_RS06810 b15d6b6cd44d8acde6fd356373ab57ec 524 Gene3D G3DSA:3.30.300.30 413 513 2.0E-33 T 06-07-2017 GTHT12_RS06810 b15d6b6cd44d8acde6fd356373ab57ec 524 ProSitePatterns PS00455 Putative AMP-binding domain signature. 166 177 - T 06-07-2017 IPR020845 AMP-binding, conserved site GTHT12_RS06810 b15d6b6cd44d8acde6fd356373ab57ec 524 Gene3D G3DSA:3.40.50.980 171 327 3.4E-46 T 06-07-2017 GTHT12_RS06810 b15d6b6cd44d8acde6fd356373ab57ec 524 Gene3D G3DSA:3.40.50.980 4 170 1.3E-43 T 06-07-2017 GTHT12_RS06810 b15d6b6cd44d8acde6fd356373ab57ec 524 SUPERFAMILY SSF56801 3 515 2.88E-160 T 06-07-2017 GTHT12_RS06810 b15d6b6cd44d8acde6fd356373ab57ec 524 Pfam PF00501 AMP-binding enzyme 9 418 2.0E-109 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GTHT12_RS06810 b15d6b6cd44d8acde6fd356373ab57ec 524 Gene3D G3DSA:2.30.38.10 329 408 1.0E-24 T 06-07-2017 GTHT12_RS00770 8031e9e83d2013225e0c5c93f4d6ee85 246 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 8.1E-22 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase GTHT12_RS00770 8031e9e83d2013225e0c5c93f4d6ee85 246 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 8.1E-22 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase GTHT12_RS00770 8031e9e83d2013225e0c5c93f4d6ee85 246 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 8.1E-22 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase GTHT12_RS00770 8031e9e83d2013225e0c5c93f4d6ee85 246 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 8.1E-22 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase GTHT12_RS00770 8031e9e83d2013225e0c5c93f4d6ee85 246 SUPERFAMILY SSF55920 1 246 7.07E-93 T 06-07-2017 IPR000994 Peptidase M24, structural domain GTHT12_RS00770 8031e9e83d2013225e0c5c93f4d6ee85 246 Pfam PF00557 Metallopeptidase family M24 12 239 6.4E-58 T 06-07-2017 IPR000994 Peptidase M24, structural domain GTHT12_RS00770 8031e9e83d2013225e0c5c93f4d6ee85 246 Gene3D G3DSA:3.90.230.10 1 246 1.7E-95 T 06-07-2017 IPR000994 Peptidase M24, structural domain GTHT12_RS00770 8031e9e83d2013225e0c5c93f4d6ee85 246 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 246 2.3E-100 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 GTHT12_RS00770 8031e9e83d2013225e0c5c93f4d6ee85 246 Hamap MF_01974 Methionine aminopeptidase [map]. 2 246 41.646 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 GTHT12_RS00770 8031e9e83d2013225e0c5c93f4d6ee85 246 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 GTHT12_RS10235 01aa5cb6bb1e764fa353f11e05b00671 333 SUPERFAMILY SSF47413 1 59 5.38E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS10235 01aa5cb6bb1e764fa353f11e05b00671 333 SMART SM00354 1 71 3.3E-30 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS10235 01aa5cb6bb1e764fa353f11e05b00671 333 Gene3D G3DSA:3.40.50.2300 172 309 2.8E-56 T 06-07-2017 GTHT12_RS10235 01aa5cb6bb1e764fa353f11e05b00671 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.2E-18 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS10235 01aa5cb6bb1e764fa353f11e05b00671 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.0E-5 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS10235 01aa5cb6bb1e764fa353f11e05b00671 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.0E-5 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS10235 01aa5cb6bb1e764fa353f11e05b00671 333 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 06-07-2017 GTHT12_RS10235 01aa5cb6bb1e764fa353f11e05b00671 333 Gene3D G3DSA:1.10.260.40 2 53 3.9E-25 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS10235 01aa5cb6bb1e764fa353f11e05b00671 333 Gene3D G3DSA:3.40.50.2300 54 171 3.5E-27 T 06-07-2017 GTHT12_RS10235 01aa5cb6bb1e764fa353f11e05b00671 333 Pfam PF13377 Periplasmic binding protein-like domain 167 328 5.9E-40 T 06-07-2017 GTHT12_RS10235 01aa5cb6bb1e764fa353f11e05b00671 333 SUPERFAMILY SSF53822 61 329 1.03E-73 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS08140 e1712587f5cf7b882017ebb8c0acc8b5 232 Pfam PF08241 Methyltransferase domain 40 134 1.4E-25 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 GTHT12_RS08140 e1712587f5cf7b882017ebb8c0acc8b5 232 SUPERFAMILY SSF53335 14 185 6.41E-43 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS08140 e1712587f5cf7b882017ebb8c0acc8b5 232 Gene3D G3DSA:3.40.50.150 23 184 2.5E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS12540 870e1fe486c1b8cf18b6db5579352879 130 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 2 126 2.6E-40 T 06-07-2017 IPR011605 NusB antitermination factor GO:0006353 GTHT12_RS12540 870e1fe486c1b8cf18b6db5579352879 130 SUPERFAMILY SSF48013 2 125 1.57E-39 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 GTHT12_RS12540 870e1fe486c1b8cf18b6db5579352879 130 Gene3D G3DSA:1.10.940.10 1 127 1.2E-42 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 GTHT12_RS12540 870e1fe486c1b8cf18b6db5579352879 130 Pfam PF01029 NusB family 5 124 1.9E-36 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 GTHT12_RS12540 870e1fe486c1b8cf18b6db5579352879 130 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 1 129 23.035 T 06-07-2017 IPR011605 NusB antitermination factor GO:0006353 GTHT12_RS00920 b7b8a02e60c4a12f859a7f74f9643c93 187 Pfam PF04542 Sigma-70 region 2 23 89 4.0E-22 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS00920 b7b8a02e60c4a12f859a7f74f9643c93 187 Gene3D G3DSA:1.10.10.10 121 186 4.1E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS00920 b7b8a02e60c4a12f859a7f74f9643c93 187 Gene3D G3DSA:1.10.1740.10 9 101 8.9E-33 T 06-07-2017 GTHT12_RS00920 b7b8a02e60c4a12f859a7f74f9643c93 187 TIGRFAM TIGR02948 SigW_bacill: RNA polymerase sigma-W factor 1 187 9.4E-111 T 06-07-2017 IPR014294 RNA polymerase sigma-W, bacillaceae GTHT12_RS00920 b7b8a02e60c4a12f859a7f74f9643c93 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 184 5.4E-41 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS00920 b7b8a02e60c4a12f859a7f74f9643c93 187 SUPERFAMILY SSF88946 8 98 2.35E-30 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS00920 b7b8a02e60c4a12f859a7f74f9643c93 187 Pfam PF08281 Sigma-70, region 4 129 180 4.3E-20 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS00920 b7b8a02e60c4a12f859a7f74f9643c93 187 SUPERFAMILY SSF88659 116 185 1.51E-20 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS15895 3d5be0901543d090e512c5ff62090b4a 394 Pfam PF00162 Phosphoglycerate kinase 6 383 6.9E-168 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15895 3d5be0901543d090e512c5ff62090b4a 394 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 5 393 43.654 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15895 3d5be0901543d090e512c5ff62090b4a 394 PRINTS PR00477 Phosphoglycerate kinase family signature 137 159 7.3E-100 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15895 3d5be0901543d090e512c5ff62090b4a 394 PRINTS PR00477 Phosphoglycerate kinase family signature 312 337 7.3E-100 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15895 3d5be0901543d090e512c5ff62090b4a 394 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 7.3E-100 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15895 3d5be0901543d090e512c5ff62090b4a 394 PRINTS PR00477 Phosphoglycerate kinase family signature 346 357 7.3E-100 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15895 3d5be0901543d090e512c5ff62090b4a 394 PRINTS PR00477 Phosphoglycerate kinase family signature 167 189 7.3E-100 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15895 3d5be0901543d090e512c5ff62090b4a 394 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 7.3E-100 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15895 3d5be0901543d090e512c5ff62090b4a 394 PRINTS PR00477 Phosphoglycerate kinase family signature 190 209 7.3E-100 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15895 3d5be0901543d090e512c5ff62090b4a 394 PRINTS PR00477 Phosphoglycerate kinase family signature 369 386 7.3E-100 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15895 3d5be0901543d090e512c5ff62090b4a 394 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 7.3E-100 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15895 3d5be0901543d090e512c5ff62090b4a 394 SUPERFAMILY SSF53748 1 393 5.89E-167 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15895 3d5be0901543d090e512c5ff62090b4a 394 Gene3D G3DSA:3.40.50.1260 3 179 1.4E-77 T 06-07-2017 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15895 3d5be0901543d090e512c5ff62090b4a 394 PIRSF PIRSF000724 1 394 1.7E-161 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15895 3d5be0901543d090e512c5ff62090b4a 394 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 06-07-2017 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15895 3d5be0901543d090e512c5ff62090b4a 394 Gene3D G3DSA:3.40.50.1270 180 381 4.0E-92 T 06-07-2017 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS00525 de87c2a05d50b2ef1970af0539cf3042 457 SUPERFAMILY SSF54211 303 455 5.31E-44 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS00525 de87c2a05d50b2ef1970af0539cf3042 457 SUPERFAMILY SSF54211 255 269 5.31E-44 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS00525 de87c2a05d50b2ef1970af0539cf3042 457 SUPERFAMILY SSF52540 70 290 6.63E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00525 de87c2a05d50b2ef1970af0539cf3042 457 Pfam PF13541 Subunit ChlI of Mg-chelatase 366 430 4.4E-9 T 06-07-2017 GTHT12_RS00525 de87c2a05d50b2ef1970af0539cf3042 457 SMART SM00382 90 244 8.4E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS00525 de87c2a05d50b2ef1970af0539cf3042 457 Gene3D G3DSA:3.30.230.10 285 454 2.4E-37 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GTHT12_RS00525 de87c2a05d50b2ef1970af0539cf3042 457 PRINTS PR01874 DNA repair protein radA signature 248 274 1.1E-93 T 06-07-2017 GTHT12_RS00525 de87c2a05d50b2ef1970af0539cf3042 457 PRINTS PR01874 DNA repair protein radA signature 322 345 1.1E-93 T 06-07-2017 GTHT12_RS00525 de87c2a05d50b2ef1970af0539cf3042 457 PRINTS PR01874 DNA repair protein radA signature 124 141 1.1E-93 T 06-07-2017 GTHT12_RS00525 de87c2a05d50b2ef1970af0539cf3042 457 PRINTS PR01874 DNA repair protein radA signature 213 241 1.1E-93 T 06-07-2017 GTHT12_RS00525 de87c2a05d50b2ef1970af0539cf3042 457 PRINTS PR01874 DNA repair protein radA signature 10 34 1.1E-93 T 06-07-2017 GTHT12_RS00525 de87c2a05d50b2ef1970af0539cf3042 457 PRINTS PR01874 DNA repair protein radA signature 82 110 1.1E-93 T 06-07-2017 GTHT12_RS00525 de87c2a05d50b2ef1970af0539cf3042 457 PRINTS PR01874 DNA repair protein radA signature 174 198 1.1E-93 T 06-07-2017 GTHT12_RS00525 de87c2a05d50b2ef1970af0539cf3042 457 Gene3D G3DSA:3.40.50.300 59 278 8.5E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00525 de87c2a05d50b2ef1970af0539cf3042 457 Pfam PF13481 AAA domain 69 222 8.4E-17 T 06-07-2017 GTHT12_RS00525 de87c2a05d50b2ef1970af0539cf3042 457 Hamap MF_01498 DNA repair protein RadA [radA]. 21 456 44.633 T 06-07-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 GTHT12_RS00525 de87c2a05d50b2ef1970af0539cf3042 457 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 452 1.9E-212 T 06-07-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 GTHT12_RS11480 67dac527c9d9f374f646db912fe2054b 223 Gene3D G3DSA:1.10.340.30 23 123 8.8E-42 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 GTHT12_RS11480 67dac527c9d9f374f646db912fe2054b 223 Hamap MF_00942 Endonuclease III [nth]. 1 211 39.242 T 06-07-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 GTHT12_RS11480 67dac527c9d9f374f646db912fe2054b 223 Pfam PF00633 Helix-hairpin-helix motif 100 128 1.1E-10 T 06-07-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 GTHT12_RS11480 67dac527c9d9f374f646db912fe2054b 223 SMART SM00478 39 187 4.2E-71 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 GTHT12_RS11480 67dac527c9d9f374f646db912fe2054b 223 SUPERFAMILY SSF48150 2 210 9.26E-77 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 GTHT12_RS11480 67dac527c9d9f374f646db912fe2054b 223 PIRSF PIRSF001435 2 214 1.2E-57 T 06-07-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 GTHT12_RS11480 67dac527c9d9f374f646db912fe2054b 223 ProSitePatterns PS01155 Endonuclease III family signature. 103 132 - T 06-07-2017 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 GTHT12_RS11480 67dac527c9d9f374f646db912fe2054b 223 Gene3D G3DSA:1.10.1670.10 124 210 1.6E-35 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 GTHT12_RS11480 67dac527c9d9f374f646db912fe2054b 223 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 170 1.6E-25 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 GTHT12_RS11480 67dac527c9d9f374f646db912fe2054b 223 TIGRFAM TIGR01083 nth: endonuclease III 5 196 1.5E-87 T 06-07-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 GTHT12_RS09460 960ec1978a3e8ce8379dbffb626fb250 593 Gene3D G3DSA:3.30.950.10 121 232 1.1E-10 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS09460 960ec1978a3e8ce8379dbffb626fb250 593 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 214 2.3E-38 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS09460 960ec1978a3e8ce8379dbffb626fb250 593 Gene3D G3DSA:3.40.1010.10 2 120 8.5E-35 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS09460 960ec1978a3e8ce8379dbffb626fb250 593 Gene3D G3DSA:3.30.413.10 452 569 3.9E-21 T 06-07-2017 GTHT12_RS09460 960ec1978a3e8ce8379dbffb626fb250 593 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 464 568 2.9E-9 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GTHT12_RS09460 960ec1978a3e8ce8379dbffb626fb250 593 SUPERFAMILY SSF56014 449 569 4.58E-24 T 06-07-2017 GTHT12_RS09460 960ec1978a3e8ce8379dbffb626fb250 593 SUPERFAMILY SSF53790 1 251 1.11E-59 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS09460 960ec1978a3e8ce8379dbffb626fb250 593 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 490 506 - T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GTHT12_RS09460 960ec1978a3e8ce8379dbffb626fb250 593 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 5 247 1.5E-101 T 06-07-2017 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 SMART SM00279 175 210 2.4E-18 T 06-07-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 6 172 3.9E-54 T 06-07-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 Pfam PF00476 DNA polymerase family A 500 876 2.2E-164 T 06-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 Gene3D G3DSA:1.10.150.20 188 248 5.1E-32 T 06-07-2017 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 174 267 3.5E-35 T 06-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 Gene3D G3DSA:1.20.1060.10 493 611 5.9E-44 T 06-07-2017 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 SMART SM00482 635 842 7.0E-127 T 06-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 SUPERFAMILY SSF56672 473 878 1.45E-161 T 06-07-2017 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 Gene3D G3DSA:3.30.420.10 302 492 9.3E-60 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 Gene3D G3DSA:1.10.150.20 662 768 1.5E-36 T 06-07-2017 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 SUPERFAMILY SSF53098 304 468 1.41E-41 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 604 626 2.6E-83 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 795 811 2.6E-83 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 825 838 2.6E-83 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 704 729 2.6E-83 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 763 774 2.6E-83 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 741 752 2.6E-83 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 627 642 2.6E-83 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 650 673 2.6E-83 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 PRINTS PR00868 DNA-polymerase family A (pol I) signature 680 693 2.6E-83 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 ProSitePatterns PS00447 DNA polymerase family A signature. 704 723 - T 06-07-2017 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 SUPERFAMILY SSF47807 173 287 7.63E-36 T 06-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 SUPERFAMILY SSF88723 2 172 5.64E-56 T 06-07-2017 IPR029060 PIN domain-like GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 Gene3D G3DSA:3.30.70.370 769 878 2.4E-66 T 06-07-2017 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 Gene3D G3DSA:3.30.70.370 612 661 2.4E-66 T 06-07-2017 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 TIGRFAM TIGR00593 pola: DNA polymerase I 7 878 0.0 T 06-07-2017 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 Gene3D G3DSA:3.40.50.1010 5 187 7.7E-73 T 06-07-2017 IPR029060 PIN domain-like GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 SMART SM00475 5 264 3.2E-153 T 06-07-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 GTHT12_RS14205 9e594c6709b399a6fc9437c1b18dd86d 878 SMART SM00474 302 468 3.0E-18 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 GTHT12_RS01640 aa088cf603b19882e1a7b0cb3a27274b 512 Gene3D G3DSA:3.40.50.1380 2 187 5.0E-88 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain GTHT12_RS01640 aa088cf603b19882e1a7b0cb3a27274b 512 SUPERFAMILY SSF52335 3 194 4.58E-73 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain GTHT12_RS01640 aa088cf603b19882e1a7b0cb3a27274b 512 SUPERFAMILY SSF53927 207 512 7.72E-130 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 GTHT12_RS01640 aa088cf603b19882e1a7b0cb3a27274b 512 PIRSF PIRSF000414 1 512 8.3E-220 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GTHT12_RS01640 aa088cf603b19882e1a7b0cb3a27274b 512 Pfam PF01808 AICARFT/IMPCHase bienzyme 135 446 5.1E-126 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GTHT12_RS01640 aa088cf603b19882e1a7b0cb3a27274b 512 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4 512 1.6E-240 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GTHT12_RS01640 aa088cf603b19882e1a7b0cb3a27274b 512 Pfam PF02142 MGS-like domain 15 130 6.2E-29 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain GTHT12_RS01640 aa088cf603b19882e1a7b0cb3a27274b 512 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 3 512 46.421 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GTHT12_RS01640 aa088cf603b19882e1a7b0cb3a27274b 512 SMART SM00798 135 447 9.8E-213 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GTHT12_RS01640 aa088cf603b19882e1a7b0cb3a27274b 512 Gene3D G3DSA:3.40.140.20 240 355 6.1E-51 T 06-07-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GTHT12_RS01640 aa088cf603b19882e1a7b0cb3a27274b 512 Gene3D G3DSA:3.40.140.20 364 502 2.3E-57 T 06-07-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GTHT12_RS01640 aa088cf603b19882e1a7b0cb3a27274b 512 SMART SM00851 15 130 9.0E-58 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain GTHT12_RS06285 13041f2322397d1ba0efbb8436506c25 293 SUPERFAMILY SSF102405 83 289 4.81E-37 T 06-07-2017 GTHT12_RS06285 13041f2322397d1ba0efbb8436506c25 293 Pfam PF02481 DNA recombination-mediator protein A 74 281 5.9E-80 T 06-07-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 GTHT12_RS06285 13041f2322397d1ba0efbb8436506c25 293 Gene3D G3DSA:3.40.50.450 115 260 1.7E-9 T 06-07-2017 GTHT12_RS06285 13041f2322397d1ba0efbb8436506c25 293 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 72 289 2.5E-78 T 06-07-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 GTHT12_RS00265 6ee537d655ba1822204564fc9e3656b7 459 Pfam PF00483 Nucleotidyl transferase 6 209 9.1E-25 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 GTHT12_RS00265 6ee537d655ba1822204564fc9e3656b7 459 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 452 2.3E-187 T 06-07-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 GTHT12_RS00265 6ee537d655ba1822204564fc9e3656b7 459 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 3 452 42.073 T 06-07-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 GTHT12_RS00265 6ee537d655ba1822204564fc9e3656b7 459 SUPERFAMILY SSF51161 254 448 2.27E-51 T 06-07-2017 IPR011004 Trimeric LpxA-like GTHT12_RS00265 6ee537d655ba1822204564fc9e3656b7 459 SUPERFAMILY SSF53448 4 306 3.6E-69 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS00265 6ee537d655ba1822204564fc9e3656b7 459 Gene3D G3DSA:3.90.550.10 3 251 2.8E-82 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS00265 6ee537d655ba1822204564fc9e3656b7 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 267 301 1.2E-8 T 06-07-2017 IPR001451 Hexapeptide repeat GTHT12_RS00265 6ee537d655ba1822204564fc9e3656b7 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 395 428 4.9E-7 T 06-07-2017 IPR001451 Hexapeptide repeat GTHT12_RS00265 6ee537d655ba1822204564fc9e3656b7 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 318 351 1.3E-6 T 06-07-2017 IPR001451 Hexapeptide repeat GTHT12_RS00265 6ee537d655ba1822204564fc9e3656b7 459 Gene3D G3DSA:2.160.10.10 254 322 9.6E-16 T 06-07-2017 GTHT12_RS00265 6ee537d655ba1822204564fc9e3656b7 459 Gene3D G3DSA:2.160.10.10 323 452 6.0E-34 T 06-07-2017 GTHT12_RS00265 6ee537d655ba1822204564fc9e3656b7 459 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 403 431 - T 06-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 GTHT12_RS17255 9690d6b76eadeff87ce23b1a5b2c5574 421 Pfam PF04932 O-Antigen ligase 204 348 2.9E-15 T 06-07-2017 IPR007016 O-antigen ligase-related GTHT12_RS06740 1db42b9c4668aab52e1f7eebc7ec3e1a 590 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 476 562 1.5E-9 T 06-07-2017 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II GTHT12_RS06740 1db42b9c4668aab52e1f7eebc7ec3e1a 590 Gene3D G3DSA:3.40.50.970 187 387 2.6E-85 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS06740 1db42b9c4668aab52e1f7eebc7ec3e1a 590 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 174 1.0E-41 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 GTHT12_RS06740 1db42b9c4668aab52e1f7eebc7ec3e1a 590 Gene3D G3DSA:3.40.920.10 5 179 1.4E-36 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 GTHT12_RS06740 1db42b9c4668aab52e1f7eebc7ec3e1a 590 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 5 573 1.8E-220 T 06-07-2017 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 GTHT12_RS06740 1db42b9c4668aab52e1f7eebc7ec3e1a 590 SUPERFAMILY SSF52922 467 580 3.61E-24 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GTHT12_RS06740 1db42b9c4668aab52e1f7eebc7ec3e1a 590 Gene3D G3DSA:3.40.50.920 468 579 2.2E-22 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GTHT12_RS06740 1db42b9c4668aab52e1f7eebc7ec3e1a 590 SUPERFAMILY SSF53323 1 221 6.28E-45 T 06-07-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 GTHT12_RS06740 1db42b9c4668aab52e1f7eebc7ec3e1a 590 SUPERFAMILY SSF52518 196 458 5.15E-73 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS06740 1db42b9c4668aab52e1f7eebc7ec3e1a 590 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 210 451 7.0E-61 T 06-07-2017 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 GTHT12_RS00405 c82d3c73ff4b08aec5adca3c6dbc6107 191 SUPERFAMILY SSF52317 1 189 1.5E-58 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS00405 c82d3c73ff4b08aec5adca3c6dbc6107 191 Gene3D G3DSA:3.40.50.880 1 189 9.1E-69 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS00405 c82d3c73ff4b08aec5adca3c6dbc6107 191 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 1.1E-13 T 06-07-2017 GTHT12_RS00405 c82d3c73ff4b08aec5adca3c6dbc6107 191 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.1E-13 T 06-07-2017 GTHT12_RS00405 c82d3c73ff4b08aec5adca3c6dbc6107 191 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.1E-13 T 06-07-2017 GTHT12_RS00405 c82d3c73ff4b08aec5adca3c6dbc6107 191 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 1.6E-7 T 06-07-2017 GTHT12_RS00405 c82d3c73ff4b08aec5adca3c6dbc6107 191 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 1.6E-7 T 06-07-2017 GTHT12_RS00405 c82d3c73ff4b08aec5adca3c6dbc6107 191 PRINTS PR00097 Anthranilate synthase component II signature 99 107 1.6E-36 T 06-07-2017 GTHT12_RS00405 c82d3c73ff4b08aec5adca3c6dbc6107 191 PRINTS PR00097 Anthranilate synthase component II signature 119 131 1.6E-36 T 06-07-2017 GTHT12_RS00405 c82d3c73ff4b08aec5adca3c6dbc6107 191 PRINTS PR00097 Anthranilate synthase component II signature 74 85 1.6E-36 T 06-07-2017 GTHT12_RS00405 c82d3c73ff4b08aec5adca3c6dbc6107 191 PRINTS PR00097 Anthranilate synthase component II signature 2 16 1.6E-36 T 06-07-2017 GTHT12_RS00405 c82d3c73ff4b08aec5adca3c6dbc6107 191 PRINTS PR00097 Anthranilate synthase component II signature 47 56 1.6E-36 T 06-07-2017 GTHT12_RS00405 c82d3c73ff4b08aec5adca3c6dbc6107 191 PRINTS PR00097 Anthranilate synthase component II signature 164 177 1.6E-36 T 06-07-2017 GTHT12_RS00405 c82d3c73ff4b08aec5adca3c6dbc6107 191 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 2.2E-87 T 06-07-2017 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 GTHT12_RS00405 c82d3c73ff4b08aec5adca3c6dbc6107 191 Pfam PF00117 Glutamine amidotransferase class-I 4 185 1.8E-56 T 06-07-2017 IPR017926 Glutamine amidotransferase GTHT12_RS12085 d25d6f172d89196b44e9ae2150413def 261 Hamap MF_01805 Segregation and condensation protein A [scpA]. 17 258 27.033 T 06-07-2017 IPR003768 Segregation and condensation protein A GTHT12_RS12085 d25d6f172d89196b44e9ae2150413def 261 Pfam PF02616 Segregation and condensation protein ScpA 34 255 3.4E-60 T 06-07-2017 IPR003768 Segregation and condensation protein A GTHT12_RS12130 954b699bc246d78b1efbd3d5ae5bacbd 439 PRINTS PR01181 Diaminopimelate decarboxylase signature 316 334 1.2E-30 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS12130 954b699bc246d78b1efbd3d5ae5bacbd 439 PRINTS PR01181 Diaminopimelate decarboxylase signature 398 420 1.2E-30 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS12130 954b699bc246d78b1efbd3d5ae5bacbd 439 PRINTS PR01181 Diaminopimelate decarboxylase signature 170 179 1.2E-30 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS12130 954b699bc246d78b1efbd3d5ae5bacbd 439 PRINTS PR01181 Diaminopimelate decarboxylase signature 81 98 1.2E-30 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS12130 954b699bc246d78b1efbd3d5ae5bacbd 439 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 235 250 - T 06-07-2017 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site GTHT12_RS12130 954b699bc246d78b1efbd3d5ae5bacbd 439 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 63 81 - T 06-07-2017 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site GTHT12_RS12130 954b699bc246d78b1efbd3d5ae5bacbd 439 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 9 430 4.9E-160 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS12130 954b699bc246d78b1efbd3d5ae5bacbd 439 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 310 407 5.2E-15 T 06-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 GTHT12_RS12130 954b699bc246d78b1efbd3d5ae5bacbd 439 Gene3D G3DSA:2.40.37.10 283 431 3.8E-52 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 GTHT12_RS12130 954b699bc246d78b1efbd3d5ae5bacbd 439 SUPERFAMILY SSF50621 273 431 2.3E-55 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 GTHT12_RS12130 954b699bc246d78b1efbd3d5ae5bacbd 439 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 19 431 42.336 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS12130 954b699bc246d78b1efbd3d5ae5bacbd 439 SUPERFAMILY SSF51419 30 299 4.36E-83 T 06-07-2017 IPR029066 PLP-binding barrel GTHT12_RS12130 954b699bc246d78b1efbd3d5ae5bacbd 439 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 39 297 5.6E-71 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 GTHT12_RS12130 954b699bc246d78b1efbd3d5ae5bacbd 439 Gene3D G3DSA:3.20.20.10 41 282 1.1E-86 T 06-07-2017 IPR029066 PLP-binding barrel GTHT12_RS12130 954b699bc246d78b1efbd3d5ae5bacbd 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 388 401 8.0E-19 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 GTHT12_RS12130 954b699bc246d78b1efbd3d5ae5bacbd 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 63 81 8.0E-19 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 GTHT12_RS12130 954b699bc246d78b1efbd3d5ae5bacbd 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 198 211 8.0E-19 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 GTHT12_RS12130 954b699bc246d78b1efbd3d5ae5bacbd 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 83 95 8.0E-19 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 GTHT12_RS12130 954b699bc246d78b1efbd3d5ae5bacbd 439 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 287 306 8.0E-19 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 GTHT12_RS05875 0491c34a8015815cb513bfdc153d3e3c 451 SUPERFAMILY SSF51984 10 100 2.49E-19 T 06-07-2017 GTHT12_RS05875 0491c34a8015815cb513bfdc153d3e3c 451 Pfam PF02875 Mur ligase family, glutamate ligase domain 311 379 9.4E-11 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GTHT12_RS05875 0491c34a8015815cb513bfdc153d3e3c 451 Gene3D G3DSA:3.40.1190.10 102 310 2.1E-64 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GTHT12_RS05875 0491c34a8015815cb513bfdc153d3e3c 451 SUPERFAMILY SSF53244 310 450 2.22E-44 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GTHT12_RS05875 0491c34a8015815cb513bfdc153d3e3c 451 Pfam PF08245 Mur ligase middle domain 117 291 7.1E-36 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GTHT12_RS05875 0491c34a8015815cb513bfdc153d3e3c 451 Gene3D G3DSA:3.90.190.20 312 447 9.3E-45 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GTHT12_RS05875 0491c34a8015815cb513bfdc153d3e3c 451 SUPERFAMILY SSF53623 103 308 3.53E-56 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GTHT12_RS05875 0491c34a8015815cb513bfdc153d3e3c 451 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 448 5.1E-141 T 06-07-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS05875 0491c34a8015815cb513bfdc153d3e3c 451 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 10 450 37.978 T 06-07-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS05875 0491c34a8015815cb513bfdc153d3e3c 451 Gene3D G3DSA:3.40.50.720 8 99 1.2E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS16560 8b732b38030b37f6dbd6546f2e44d7b9 359 Pfam PF00676 Dehydrogenase E1 component 38 321 4.1E-93 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 GTHT12_RS16560 8b732b38030b37f6dbd6546f2e44d7b9 359 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 10 348 9.4E-150 T 06-07-2017 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 GTHT12_RS16560 8b732b38030b37f6dbd6546f2e44d7b9 359 SUPERFAMILY SSF52518 9 349 1.2E-108 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS16560 8b732b38030b37f6dbd6546f2e44d7b9 359 Gene3D G3DSA:3.40.50.970 8 348 1.8E-135 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS08695 6a46915447a27ec743b2f1105afc9d41 67 Pfam PF00403 Heavy-metal-associated domain 4 65 8.0E-18 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 GTHT12_RS08695 6a46915447a27ec743b2f1105afc9d41 67 SUPERFAMILY SSF55008 1 67 1.44E-22 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 GTHT12_RS08695 6a46915447a27ec743b2f1105afc9d41 67 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 06-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 GTHT12_RS08695 6a46915447a27ec743b2f1105afc9d41 67 PRINTS PR00946 Mercury scavenger protein signature 26 41 2.2E-7 T 06-07-2017 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 GTHT12_RS08695 6a46915447a27ec743b2f1105afc9d41 67 PRINTS PR00946 Mercury scavenger protein signature 55 67 2.2E-7 T 06-07-2017 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 GTHT12_RS08695 6a46915447a27ec743b2f1105afc9d41 67 PRINTS PR00946 Mercury scavenger protein signature 41 55 2.2E-7 T 06-07-2017 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 GTHT12_RS08695 6a46915447a27ec743b2f1105afc9d41 67 PRINTS PR00946 Mercury scavenger protein signature 10 26 2.2E-7 T 06-07-2017 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 GTHT12_RS08695 6a46915447a27ec743b2f1105afc9d41 67 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 3 67 3.6E-22 T 06-07-2017 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 GTHT12_RS08695 6a46915447a27ec743b2f1105afc9d41 67 Gene3D G3DSA:3.30.70.100 1 66 3.4E-25 T 06-07-2017 GTHT12_RS14145 6fabd6a63801e9ba07a343b46b134d44 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 3.3E-22 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 GTHT12_RS14145 6fabd6a63801e9ba07a343b46b134d44 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 3.3E-22 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 GTHT12_RS14145 6fabd6a63801e9ba07a343b46b134d44 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 3.3E-22 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 GTHT12_RS14145 6fabd6a63801e9ba07a343b46b134d44 66 SUPERFAMILY SSF143034 2 62 8.76E-23 T 06-07-2017 GTHT12_RS14145 6fabd6a63801e9ba07a343b46b134d44 66 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 06-07-2017 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS14145 6fabd6a63801e9ba07a343b46b134d44 66 Pfam PF01632 Ribosomal protein L35 2 62 6.7E-26 T 06-07-2017 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS14145 6fabd6a63801e9ba07a343b46b134d44 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 1.0E-26 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 GTHT12_RS14145 6fabd6a63801e9ba07a343b46b134d44 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 19.125 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 GTHT12_RS03330 e263d315eba96b790283ee7eb2f8c0e6 226 PIRSF PIRSF006171 1 226 5.1E-82 T 06-07-2017 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 GTHT12_RS03330 e263d315eba96b790283ee7eb2f8c0e6 226 SUPERFAMILY SSF52172 1 154 1.99E-40 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS03330 e263d315eba96b790283ee7eb2f8c0e6 226 SMART SM00448 2 115 1.3E-36 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS03330 e263d315eba96b790283ee7eb2f8c0e6 226 Gene3D G3DSA:3.40.50.2300 1 127 1.0E-37 T 06-07-2017 GTHT12_RS03330 e263d315eba96b790283ee7eb2f8c0e6 226 SUPERFAMILY SSF46785 164 209 5.25E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS03330 e263d315eba96b790283ee7eb2f8c0e6 226 Pfam PF00072 Response regulator receiver domain 4 115 8.8E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS03330 e263d315eba96b790283ee7eb2f8c0e6 226 Pfam PF04703 FaeA-like protein 163 205 5.4E-6 T 06-07-2017 IPR006793 FaeA-like protein GO:0006355|GO:0009289 GTHT12_RS03330 e263d315eba96b790283ee7eb2f8c0e6 226 Gene3D G3DSA:1.10.10.10 161 207 1.1E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS10105 fc6334ba1f6d1d078c53b667e9bfdb6c 350 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 123 5.7E-26 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 GTHT12_RS10105 fc6334ba1f6d1d078c53b667e9bfdb6c 350 SUPERFAMILY SSF51735 3 155 6.04E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS10105 fc6334ba1f6d1d078c53b667e9bfdb6c 350 TIGRFAM TIGR04380 myo_inos_iolG: inositol 2-dehydrogenase 4 338 2.6E-108 T 06-07-2017 IPR030827 Inositol 2-dehydrogenase GTHT12_RS10105 fc6334ba1f6d1d078c53b667e9bfdb6c 350 Gene3D G3DSA:3.40.50.720 1 138 6.5E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS10105 fc6334ba1f6d1d078c53b667e9bfdb6c 350 SUPERFAMILY SSF55347 134 312 3.53E-33 T 06-07-2017 GTHT12_RS10105 fc6334ba1f6d1d078c53b667e9bfdb6c 350 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 138 248 1.0E-10 T 06-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10105 fc6334ba1f6d1d078c53b667e9bfdb6c 350 Gene3D G3DSA:3.30.360.10 139 341 4.3E-55 T 06-07-2017 GTHT12_RS04870 ab5fdd3c25bfe4ba2ca0c3cbc52af5ff 178 TIGRFAM TIGR00277 HDIG: HDIG domain 22 91 7.9E-11 T 06-07-2017 IPR006675 HDIG domain GTHT12_RS04870 ab5fdd3c25bfe4ba2ca0c3cbc52af5ff 178 Pfam PF01966 HD domain 24 135 1.2E-16 T 06-07-2017 IPR006674 HD domain GTHT12_RS04870 ab5fdd3c25bfe4ba2ca0c3cbc52af5ff 178 Gene3D G3DSA:1.10.3210.10 16 169 1.5E-20 T 06-07-2017 IPR006674 HD domain GTHT12_RS04870 ab5fdd3c25bfe4ba2ca0c3cbc52af5ff 178 SUPERFAMILY SSF109604 16 137 2.22E-23 T 06-07-2017 GTHT12_RS04870 ab5fdd3c25bfe4ba2ca0c3cbc52af5ff 178 SMART SM00471 19 148 7.1E-7 T 06-07-2017 IPR003607 HD/PDEase domain GTHT12_RS12195 2a5894f2dd72efd944d1f5e5f221d0e0 391 SUPERFAMILY SSF56601 4 282 1.11E-82 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS12195 2a5894f2dd72efd944d1f5e5f221d0e0 391 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 32 262 1.3E-91 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 GTHT12_RS12195 2a5894f2dd72efd944d1f5e5f221d0e0 391 SMART SM00936 282 373 6.6E-25 T 06-07-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 GTHT12_RS12195 2a5894f2dd72efd944d1f5e5f221d0e0 391 Gene3D G3DSA:3.40.710.10 9 280 6.0E-100 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS12195 2a5894f2dd72efd944d1f5e5f221d0e0 391 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 145 158 3.4E-17 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 GTHT12_RS12195 2a5894f2dd72efd944d1f5e5f221d0e0 391 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 65 76 3.4E-17 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 GTHT12_RS12195 2a5894f2dd72efd944d1f5e5f221d0e0 391 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 118 135 3.4E-17 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 GTHT12_RS12195 2a5894f2dd72efd944d1f5e5f221d0e0 391 SUPERFAMILY SSF69189 274 371 7.65E-20 T 06-07-2017 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 GTHT12_RS12195 2a5894f2dd72efd944d1f5e5f221d0e0 391 Gene3D G3DSA:2.60.410.10 282 373 9.0E-21 T 06-07-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 GTHT12_RS12195 2a5894f2dd72efd944d1f5e5f221d0e0 391 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 282 372 3.1E-16 T 06-07-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 GTHT12_RS14890 233f07d49c459d0407990a9ed60dbdbf 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 8.6E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 GTHT12_RS14890 233f07d49c459d0407990a9ed60dbdbf 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 87 100 8.6E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 GTHT12_RS14890 233f07d49c459d0407990a9ed60dbdbf 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 41 56 8.6E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 GTHT12_RS14890 233f07d49c459d0407990a9ed60dbdbf 266 SUPERFAMILY SSF53474 2 264 2.03E-64 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS14890 233f07d49c459d0407990a9ed60dbdbf 266 Gene3D G3DSA:3.40.50.1820 2 264 1.1E-65 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS14890 233f07d49c459d0407990a9ed60dbdbf 266 TIGRFAM TIGR03695 menH_SHCHC: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 17 263 1.1E-90 T 06-07-2017 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 GTHT12_RS14890 233f07d49c459d0407990a9ed60dbdbf 266 Hamap MF_01660 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [menH]. 8 264 38.211 T 06-07-2017 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 GTHT12_RS14890 233f07d49c459d0407990a9ed60dbdbf 266 Pfam PF00561 alpha/beta hydrolase fold 18 251 1.6E-27 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 GTHT12_RS00710 2b094efc13ca72bc146c2ab57b06942c 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 5.9E-59 T 06-07-2017 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 GTHT12_RS00710 2b094efc13ca72bc146c2ab57b06942c 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 06-07-2017 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00710 2b094efc13ca72bc146c2ab57b06942c 122 SUPERFAMILY SSF50193 1 122 2.09E-51 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00710 2b094efc13ca72bc146c2ab57b06942c 122 Gene3D G3DSA:2.40.150.20 1 122 9.6E-54 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00710 2b094efc13ca72bc146c2ab57b06942c 122 SMART SM01374 1 122 5.8E-87 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00710 2b094efc13ca72bc146c2ab57b06942c 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 2.6E-54 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00710 2b094efc13ca72bc146c2ab57b06942c 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.294 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 GTHT12_RS09415 d2c23584530f6b68d74ad09f7f5a90c9 454 Gene3D G3DSA:3.40.50.300 1 194 5.6E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS09415 d2c23584530f6b68d74ad09f7f5a90c9 454 Gene3D G3DSA:3.40.50.880 245 450 1.1E-28 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS09415 d2c23584530f6b68d74ad09f7f5a90c9 454 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 193 1.6E-27 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain GTHT12_RS09415 d2c23584530f6b68d74ad09f7f5a90c9 454 SUPERFAMILY SSF52540 1 194 1.84E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS09415 d2c23584530f6b68d74ad09f7f5a90c9 454 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 3 445 3.2E-140 T 06-07-2017 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 GTHT12_RS09415 d2c23584530f6b68d74ad09f7f5a90c9 454 SUPERFAMILY SSF52317 244 446 5.04E-34 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS09415 d2c23584530f6b68d74ad09f7f5a90c9 454 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 1 437 46.202 T 06-07-2017 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 GTHT12_RS09415 d2c23584530f6b68d74ad09f7f5a90c9 454 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 246 436 3.0E-39 T 06-07-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 GTHT12_RS02405 ab3605a23fbf53440c055766a9180a14 802 SMART SM00267 363 532 4.5E-33 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS02405 ab3605a23fbf53440c055766a9180a14 802 Gene3D G3DSA:3.30.450.20 252 361 3.5E-16 T 06-07-2017 GTHT12_RS02405 ab3605a23fbf53440c055766a9180a14 802 Gene3D G3DSA:3.20.20.450 546 792 1.2E-96 T 06-07-2017 IPR001633 EAL domain GTHT12_RS02405 ab3605a23fbf53440c055766a9180a14 802 SUPERFAMILY SSF141868 547 793 1.96E-89 T 06-07-2017 IPR001633 EAL domain GTHT12_RS02405 ab3605a23fbf53440c055766a9180a14 802 Pfam PF00563 EAL domain 548 779 9.4E-74 T 06-07-2017 IPR001633 EAL domain GTHT12_RS02405 ab3605a23fbf53440c055766a9180a14 802 Pfam PF13426 PAS domain 270 361 9.7E-12 T 06-07-2017 IPR000014 PAS domain GTHT12_RS02405 ab3605a23fbf53440c055766a9180a14 802 Pfam PF00990 Diguanylate cyclase, GGDEF domain 375 524 7.0E-34 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS02405 ab3605a23fbf53440c055766a9180a14 802 Gene3D G3DSA:3.30.70.270 376 539 5.2E-40 T 06-07-2017 GTHT12_RS02405 ab3605a23fbf53440c055766a9180a14 802 SMART SM00052 542 784 9.6E-117 T 06-07-2017 IPR001633 EAL domain GTHT12_RS02405 ab3605a23fbf53440c055766a9180a14 802 SUPERFAMILY SSF55073 379 528 1.02E-34 T 06-07-2017 IPR029787 Nucleotide cyclase GTHT12_RS02405 ab3605a23fbf53440c055766a9180a14 802 SMART SM00091 259 323 7.6E-5 T 06-07-2017 IPR000014 PAS domain GTHT12_RS02405 ab3605a23fbf53440c055766a9180a14 802 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 256 368 9.8E-15 T 06-07-2017 IPR000014 PAS domain GTHT12_RS02405 ab3605a23fbf53440c055766a9180a14 802 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 375 524 5.1E-28 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS02405 ab3605a23fbf53440c055766a9180a14 802 SUPERFAMILY SSF55785 252 361 5.41E-18 T 06-07-2017 IPR000014 PAS domain GTHT12_RS12730 369037c0dedd9bfbb93b82b8cf5bf9cc 448 SUPERFAMILY SSF53383 3 443 1.77E-127 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS12730 369037c0dedd9bfbb93b82b8cf5bf9cc 448 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 446 50.946 T 06-07-2017 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 GTHT12_RS12730 369037c0dedd9bfbb93b82b8cf5bf9cc 448 PIRSF PIRSF006815 3 447 2.4E-191 T 06-07-2017 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 GTHT12_RS12730 369037c0dedd9bfbb93b82b8cf5bf9cc 448 Gene3D G3DSA:3.40.640.10 87 337 3.9E-28 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS12730 369037c0dedd9bfbb93b82b8cf5bf9cc 448 Pfam PF02347 Glycine cleavage system P-protein 3 442 1.8E-160 T 06-07-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 GTHT12_RS01295 58fd3722070794a2546cd969a8d7bcaf 467 Gene3D G3DSA:3.40.50.300 209 370 5.1E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01295 58fd3722070794a2546cd969a8d7bcaf 467 Gene3D G3DSA:3.40.50.300 2 208 2.8E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01295 58fd3722070794a2546cd969a8d7bcaf 467 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 06-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site GTHT12_RS01295 58fd3722070794a2546cd969a8d7bcaf 467 SMART SM00487 21 218 1.2E-66 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain GTHT12_RS01295 58fd3722070794a2546cd969a8d7bcaf 467 SUPERFAMILY SSF52540 71 356 4.38E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01295 58fd3722070794a2546cd969a8d7bcaf 467 Pfam PF00270 DEAD/DEAH box helicase 26 190 1.6E-51 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 GTHT12_RS01295 58fd3722070794a2546cd969a8d7bcaf 467 SMART SM00490 254 335 3.5E-35 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS01295 58fd3722070794a2546cd969a8d7bcaf 467 Hamap MF_01493 DEAD-box ATP-dependent RNA helicase CshA [cshA]. 2 467 44.712 T 06-07-2017 IPR030880 DEAD-box ATP-dependent RNA helicase CshA GO:0004004|GO:0005524|GO:0010501 GTHT12_RS01295 58fd3722070794a2546cd969a8d7bcaf 467 Pfam PF00271 Helicase conserved C-terminal domain 227 335 3.2E-29 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS03940 92bcd60af3fd40db50584704e4e157cb 436 Gene3D G3DSA:4.10.320.10 137 185 1.4E-16 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS03940 92bcd60af3fd40db50584704e4e157cb 436 Gene3D G3DSA:4.10.320.10 91 136 5.6E-13 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS03940 92bcd60af3fd40db50584704e4e157cb 436 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 206 434 1.4E-83 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS03940 92bcd60af3fd40db50584704e4e157cb 436 SUPERFAMILY SSF52777 202 434 2.22E-83 T 06-07-2017 GTHT12_RS03940 92bcd60af3fd40db50584704e4e157cb 436 Gene3D G3DSA:2.40.50.100 1 80 8.1E-23 T 06-07-2017 GTHT12_RS03940 92bcd60af3fd40db50584704e4e157cb 436 SUPERFAMILY SSF47005 91 129 3.53E-9 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS03940 92bcd60af3fd40db50584704e4e157cb 436 Pfam PF02817 e3 binding domain 92 127 1.4E-11 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS03940 92bcd60af3fd40db50584704e4e157cb 436 Pfam PF02817 e3 binding domain 142 177 9.8E-13 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS03940 92bcd60af3fd40db50584704e4e157cb 436 SUPERFAMILY SSF47005 139 180 2.09E-10 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS03940 92bcd60af3fd40db50584704e4e157cb 436 SUPERFAMILY SSF51230 1 83 3.02E-22 T 06-07-2017 IPR011053 Single hybrid motif GTHT12_RS03940 92bcd60af3fd40db50584704e4e157cb 436 Pfam PF00364 Biotin-requiring enzyme 4 76 5.0E-19 T 06-07-2017 IPR000089 Biotin/lipoyl attachment GTHT12_RS03940 92bcd60af3fd40db50584704e4e157cb 436 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 GTHT12_RS03940 92bcd60af3fd40db50584704e4e157cb 436 Gene3D G3DSA:3.30.559.10 198 433 6.7E-87 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 GTHT12_RS17635 151d743a97ee5492a8c1e7d6abd975a0 1085 Hamap MF_02050 Fused isobutyryl-CoA mutase [icmF]. 10 1085 17.429 T 06-07-2017 IPR033669 Fused isobutyryl-CoA mutase GO:0003924|GO:0005525|GO:0006637|GO:0031419|GO:0034784|GO:0047727 GTHT12_RS17635 151d743a97ee5492a8c1e7d6abd975a0 1085 Gene3D G3DSA:3.40.50.300 198 372 4.9E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17635 151d743a97ee5492a8c1e7d6abd975a0 1085 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 10 123 4.0E-17 T 06-07-2017 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 GTHT12_RS17635 151d743a97ee5492a8c1e7d6abd975a0 1085 SUPERFAMILY SSF51703 502 1081 1.28E-154 T 06-07-2017 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 GTHT12_RS17635 151d743a97ee5492a8c1e7d6abd975a0 1085 Pfam PF03308 ArgK protein 165 461 2.0E-43 T 06-07-2017 GTHT12_RS17635 151d743a97ee5492a8c1e7d6abd975a0 1085 SUPERFAMILY SSF52242 4 143 1.44E-42 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 GTHT12_RS17635 151d743a97ee5492a8c1e7d6abd975a0 1085 Gene3D G3DSA:3.40.50.280 4 138 2.8E-38 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 GTHT12_RS17635 151d743a97ee5492a8c1e7d6abd975a0 1085 Pfam PF01642 Methylmalonyl-CoA mutase 560 1079 2.9E-142 T 06-07-2017 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 GTHT12_RS17635 151d743a97ee5492a8c1e7d6abd975a0 1085 Pfam PF02310 B12 binding domain 12 108 1.3E-12 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 GTHT12_RS17635 151d743a97ee5492a8c1e7d6abd975a0 1085 Gene3D G3DSA:3.20.20.240 534 1081 3.4E-196 T 06-07-2017 IPR014348 Cobalamin (vitamin B12)-dependent enzyme, catalytic subdomain GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 GTHT12_RS17635 151d743a97ee5492a8c1e7d6abd975a0 1085 SUPERFAMILY SSF52540 148 463 6.8E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00675 bb975c93cfd441f80cfdfea196c7a3d4 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 6.5E-35 T 06-07-2017 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00675 bb975c93cfd441f80cfdfea196c7a3d4 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 06-07-2017 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00675 bb975c93cfd441f80cfdfea196c7a3d4 276 PIRSF PIRSF002158 3 276 6.7E-103 T 06-07-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00675 bb975c93cfd441f80cfdfea196c7a3d4 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 50.611 T 06-07-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00675 bb975c93cfd441f80cfdfea196c7a3d4 276 Gene3D G3DSA:4.10.950.10 196 275 3.7E-37 T 06-07-2017 IPR014726 Ribosomal protein L2, domain 3 GTHT12_RS00675 bb975c93cfd441f80cfdfea196c7a3d4 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 4.7E-58 T 06-07-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00675 bb975c93cfd441f80cfdfea196c7a3d4 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 276 2.6E-142 T 06-07-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00675 bb975c93cfd441f80cfdfea196c7a3d4 276 SMART SM01383 42 118 1.3E-48 T 06-07-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00675 bb975c93cfd441f80cfdfea196c7a3d4 276 SMART SM01382 124 253 8.4E-94 T 06-07-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00675 bb975c93cfd441f80cfdfea196c7a3d4 276 SUPERFAMILY SSF50104 126 273 1.26E-61 T 06-07-2017 IPR008991 Translation protein SH3-like domain GTHT12_RS00675 bb975c93cfd441f80cfdfea196c7a3d4 276 Gene3D G3DSA:2.30.30.30 118 195 2.7E-36 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 GTHT12_RS00675 bb975c93cfd441f80cfdfea196c7a3d4 276 Gene3D G3DSA:2.40.50.140 1 113 9.8E-56 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS00675 bb975c93cfd441f80cfdfea196c7a3d4 276 SUPERFAMILY SSF50249 2 125 5.48E-53 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS05195 78e3d1ee90a352890badd025d4841ce9 702 SUPERFAMILY SSF56349 357 552 9.71E-36 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 GTHT12_RS05195 78e3d1ee90a352890badd025d4841ce9 702 Pfam PF00589 Phage integrase family 366 542 3.4E-25 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS05195 78e3d1ee90a352890badd025d4841ce9 702 Gene3D G3DSA:1.10.443.10 367 550 1.0E-32 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS16245 1b020579213622a402ca6d6fcc454228 140 TIGRFAM TIGR03826 YvyF: flagellar operon protein TIGR03826 2 135 1.3E-55 T 06-07-2017 IPR022258 Flagellar operon protein YvyF GTHT12_RS08940 8f1bdb1bd995f8fa572d69ae4a685864 177 Pfam PF00583 Acetyltransferase (GNAT) family 61 145 9.5E-14 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS08940 8f1bdb1bd995f8fa572d69ae4a685864 177 Gene3D G3DSA:3.40.630.30 2 149 1.9E-27 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS08940 8f1bdb1bd995f8fa572d69ae4a685864 177 SUPERFAMILY SSF55729 2 149 1.69E-27 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS16370 9841e1226a998718f7908ad937d5308a 719 Pfam PF13457 SH3-like domain 130 184 14.0 T 06-07-2017 IPR025987 SH3-like domain KEGG: 00511+3.2.1.96 GTHT12_RS16370 9841e1226a998718f7908ad937d5308a 719 Pfam PF13457 SH3-like domain 290 342 9.0 T 06-07-2017 IPR025987 SH3-like domain KEGG: 00511+3.2.1.96 GTHT12_RS16370 9841e1226a998718f7908ad937d5308a 719 Pfam PF13457 SH3-like domain 210 265 0.041 T 06-07-2017 IPR025987 SH3-like domain KEGG: 00511+3.2.1.96 GTHT12_RS16370 9841e1226a998718f7908ad937d5308a 719 Pfam PF13457 SH3-like domain 50 105 0.042 T 06-07-2017 IPR025987 SH3-like domain KEGG: 00511+3.2.1.96 GTHT12_RS16370 9841e1226a998718f7908ad937d5308a 719 SMART SM00047 558 710 7.7E-42 T 06-07-2017 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 GTHT12_RS16370 9841e1226a998718f7908ad937d5308a 719 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 571 703 1.5E-12 T 06-07-2017 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 GTHT12_RS16370 9841e1226a998718f7908ad937d5308a 719 SMART SM00287 393 465 5.2 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS16370 9841e1226a998718f7908ad937d5308a 719 SMART SM00287 466 536 1.5E-8 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS16370 9841e1226a998718f7908ad937d5308a 719 Pfam PF08239 Bacterial SH3 domain 475 511 2.1E-7 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS05670 01b19b816da2a737a50fbe8da56687b8 95 Hamap MF_01560 UPF0358 protein . 2 92 27.24 T 06-07-2017 IPR009983 Uncharacterised protein family UPF0358 GTHT12_RS05670 01b19b816da2a737a50fbe8da56687b8 95 Gene3D G3DSA:1.10.287.750 3 84 9.2E-41 T 06-07-2017 IPR009983 Uncharacterised protein family UPF0358 GTHT12_RS05670 01b19b816da2a737a50fbe8da56687b8 95 SUPERFAMILY SSF140404 5 83 6.28E-37 T 06-07-2017 IPR009983 Uncharacterised protein family UPF0358 GTHT12_RS05670 01b19b816da2a737a50fbe8da56687b8 95 Pfam PF07408 Protein of unknown function (DUF1507) 9 90 8.2E-42 T 06-07-2017 IPR009983 Uncharacterised protein family UPF0358 GTHT12_RS05830 c2e9ae6590e95b9d1c5d4a91537b6e6a 128 PIRSF PIRSF030092 1 128 1.8E-41 T 06-07-2017 IPR016945 Uncharacterised conserved protein UCP030092 GTHT12_RS05830 c2e9ae6590e95b9d1c5d4a91537b6e6a 128 Pfam PF11877 Protein of unknown function (DUF3397) 10 120 5.9E-26 T 06-07-2017 IPR024515 Protein of unknown function DUF3397 GTHT12_RS06370 78159c5e7701303c9f59922174a76064 264 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 136 2.2E-44 T 06-07-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G GTHT12_RS06370 78159c5e7701303c9f59922174a76064 264 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 149 245 8.6E-36 T 06-07-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G GTHT12_RS06370 78159c5e7701303c9f59922174a76064 264 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 185 262 4.1E-26 T 06-07-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain GTHT12_RS06370 78159c5e7701303c9f59922174a76064 264 SUPERFAMILY SSF117143 92 224 2.22E-43 T 06-07-2017 GTHT12_RS06370 78159c5e7701303c9f59922174a76064 264 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 5 243 4.5E-57 T 06-07-2017 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 GTHT12_RS06370 78159c5e7701303c9f59922174a76064 264 Pfam PF00460 Flagella basal body rod protein 5 35 3.6E-12 T 06-07-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 GTHT12_RS01955 99b2bc8c599098628c1ee5e06f01a80a 257 Pfam PF00005 ABC transporter 23 171 1.3E-36 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS01955 99b2bc8c599098628c1ee5e06f01a80a 257 SMART SM00382 32 227 7.9E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS01955 99b2bc8c599098628c1ee5e06f01a80a 257 Gene3D G3DSA:3.40.50.300 3 223 1.6E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01955 99b2bc8c599098628c1ee5e06f01a80a 257 SUPERFAMILY SSF52540 4 224 7.93E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03490 5593568bdfbf5139cc31e701cab12774 484 Pfam PF00005 ABC transporter 279 414 1.1E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS03490 5593568bdfbf5139cc31e701cab12774 484 Pfam PF00005 ABC transporter 23 161 1.4E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS03490 5593568bdfbf5139cc31e701cab12774 484 Gene3D G3DSA:3.40.50.300 5 225 1.2E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03490 5593568bdfbf5139cc31e701cab12774 484 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS03490 5593568bdfbf5139cc31e701cab12774 484 SMART SM00382 281 463 2.2E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS03490 5593568bdfbf5139cc31e701cab12774 484 SMART SM00382 31 208 9.4E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS03490 5593568bdfbf5139cc31e701cab12774 484 Gene3D G3DSA:3.40.50.300 279 467 1.7E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03490 5593568bdfbf5139cc31e701cab12774 484 ProSitePatterns PS00211 ABC transporters family signature. 387 401 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS03490 5593568bdfbf5139cc31e701cab12774 484 SUPERFAMILY SSF52540 5 224 5.45E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03490 5593568bdfbf5139cc31e701cab12774 484 SUPERFAMILY SSF52540 278 467 2.28E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17500 fda8f947dac603618353e4766941c8e4 70 Hamap MF_01396 ATP synthase subunit c [atpH]. 2 70 16.722 T 06-07-2017 GTHT12_RS17500 fda8f947dac603618353e4766941c8e4 70 PRINTS PR00124 ATP synthase C subunit signature 43 68 5.4E-20 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 GTHT12_RS17500 fda8f947dac603618353e4766941c8e4 70 PRINTS PR00124 ATP synthase C subunit signature 26 41 5.4E-20 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 GTHT12_RS17500 fda8f947dac603618353e4766941c8e4 70 PRINTS PR00124 ATP synthase C subunit signature 5 24 5.4E-20 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 GTHT12_RS17500 fda8f947dac603618353e4766941c8e4 70 SUPERFAMILY SSF81333 3 67 6.41E-20 T 06-07-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 GTHT12_RS17500 fda8f947dac603618353e4766941c8e4 70 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 13 67 1.0E-24 T 06-07-2017 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 GTHT12_RS17500 fda8f947dac603618353e4766941c8e4 70 ProSitePatterns PS00605 ATP synthase c subunit signature. 33 54 - T 06-07-2017 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210 GTHT12_RS17500 fda8f947dac603618353e4766941c8e4 70 Gene3D G3DSA:1.20.20.10 2 67 6.0E-29 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 GTHT12_RS17500 fda8f947dac603618353e4766941c8e4 70 Pfam PF00137 ATP synthase subunit C 4 66 3.2E-15 T 06-07-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 GTHT12_RS09110 065923cf5c38e8f03ec7294e484d54f0 412 Gene3D G3DSA:2.40.30.10 157 268 6.9E-38 T 06-07-2017 GTHT12_RS09110 065923cf5c38e8f03ec7294e484d54f0 412 Pfam PF00175 Oxidoreductase NAD-binding domain 278 384 2.1E-11 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 GTHT12_RS09110 065923cf5c38e8f03ec7294e484d54f0 412 Pfam PF00042 Globin 12 108 5.2E-12 T 06-07-2017 IPR000971 Globin GO:0019825|GO:0020037 GTHT12_RS09110 065923cf5c38e8f03ec7294e484d54f0 412 SUPERFAMILY SSF46458 7 148 1.45E-42 T 06-07-2017 IPR009050 Globin-like GTHT12_RS09110 065923cf5c38e8f03ec7294e484d54f0 412 SUPERFAMILY SSF52343 270 407 2.62E-39 T 06-07-2017 GTHT12_RS09110 065923cf5c38e8f03ec7294e484d54f0 412 Hamap MF_01252 Flavohemoprotein [hmp]. 6 409 56.504 T 06-07-2017 IPR023950 Flavohemoprotein GO:0008941|GO:0019825|GO:0020037|GO:0051409|GO:0055114|GO:0071949 GTHT12_RS09110 065923cf5c38e8f03ec7294e484d54f0 412 Gene3D G3DSA:1.10.490.10 8 147 2.3E-55 T 06-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 GTHT12_RS09110 065923cf5c38e8f03ec7294e484d54f0 412 SUPERFAMILY SSF63380 157 268 1.12E-30 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 GTHT12_RS09110 065923cf5c38e8f03ec7294e484d54f0 412 Gene3D G3DSA:3.40.50.80 272 406 4.6E-36 T 06-07-2017 GTHT12_RS09110 065923cf5c38e8f03ec7294e484d54f0 412 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 191 201 4.8E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 GTHT12_RS09110 065923cf5c38e8f03ec7294e484d54f0 412 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 212 219 4.8E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 GTHT12_RS09110 065923cf5c38e8f03ec7294e484d54f0 412 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 241 250 4.8E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 GTHT12_RS09110 065923cf5c38e8f03ec7294e484d54f0 412 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 277 296 4.8E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 GTHT12_RS09110 065923cf5c38e8f03ec7294e484d54f0 412 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 371 379 4.8E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 GTHT12_RS09110 065923cf5c38e8f03ec7294e484d54f0 412 Pfam PF00970 Oxidoreductase FAD-binding domain 164 266 4.1E-12 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 GTHT12_RS11705 d742e8753463d45e97bc821cf63efa72 188 Gene3D G3DSA:3.30.1130.10 58 187 1.9E-61 T 06-07-2017 GTHT12_RS11705 d742e8753463d45e97bc821cf63efa72 188 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 5 187 42.746 T 06-07-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 GTHT12_RS11705 d742e8753463d45e97bc821cf63efa72 188 Gene3D G3DSA:1.10.286.10 4 55 1.2E-25 T 06-07-2017 GTHT12_RS11705 d742e8753463d45e97bc821cf63efa72 188 Pfam PF01227 GTP cyclohydrolase I 9 186 6.0E-81 T 06-07-2017 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 GTHT12_RS11705 d742e8753463d45e97bc821cf63efa72 188 SUPERFAMILY SSF55620 3 187 6.45E-79 T 06-07-2017 GTHT12_RS11705 d742e8753463d45e97bc821cf63efa72 188 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 65 81 - T 06-07-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 GTHT12_RS11705 d742e8753463d45e97bc821cf63efa72 188 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 114 124 - T 06-07-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 GTHT12_RS11705 d742e8753463d45e97bc821cf63efa72 188 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 9 187 1.3E-79 T 06-07-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 GTHT12_RS00755 f054f7fe379e36c41b13339a6ed0f990 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 143 1.5E-56 T 06-07-2017 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00755 f054f7fe379e36c41b13339a6ed0f990 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 06-07-2017 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00755 f054f7fe379e36c41b13339a6ed0f990 146 SUPERFAMILY SSF52080 4 143 2.75E-52 T 06-07-2017 IPR021131 Ribosomal protein L18e/L15P GTHT12_RS00755 f054f7fe379e36c41b13339a6ed0f990 146 Gene3D G3DSA:3.100.10.10 32 146 2.5E-43 T 06-07-2017 GTHT12_RS00755 f054f7fe379e36c41b13339a6ed0f990 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 23.384 T 06-07-2017 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 GTHT12_RS00755 f054f7fe379e36c41b13339a6ed0f990 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 7.6E-40 T 06-07-2017 IPR021131 Ribosomal protein L18e/L15P GTHT12_RS15625 1014564992e0607ab94e5eaa48a12278 342 SUPERFAMILY SSF55021 249 340 4.92E-23 T 06-07-2017 GTHT12_RS15625 1014564992e0607ab94e5eaa48a12278 342 Gene3D G3DSA:3.30.70.260 237 340 2.4E-29 T 06-07-2017 GTHT12_RS15625 1014564992e0607ab94e5eaa48a12278 342 SMART SM00930 263 338 1.0E-27 T 06-07-2017 IPR018449 NIL domain GTHT12_RS15625 1014564992e0607ab94e5eaa48a12278 342 SUPERFAMILY SSF52540 1 240 2.97E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS15625 1014564992e0607ab94e5eaa48a12278 342 Pfam PF00005 ABC transporter 21 169 1.2E-37 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS15625 1014564992e0607ab94e5eaa48a12278 342 Pfam PF09383 NIL domain 267 337 7.2E-20 T 06-07-2017 IPR018449 NIL domain GTHT12_RS15625 1014564992e0607ab94e5eaa48a12278 342 Gene3D G3DSA:3.40.50.300 1 236 1.5E-89 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS15625 1014564992e0607ab94e5eaa48a12278 342 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS15625 1014564992e0607ab94e5eaa48a12278 342 SMART SM00382 30 218 1.7E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS16820 26fc8bd2f53bd0c3eee7f2220ff9ee39 352 Gene3D G3DSA:2.115.10.20 3 51 1.6E-110 T 06-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain GTHT12_RS16820 26fc8bd2f53bd0c3eee7f2220ff9ee39 352 Gene3D G3DSA:2.115.10.20 104 349 1.6E-110 T 06-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain GTHT12_RS16820 26fc8bd2f53bd0c3eee7f2220ff9ee39 352 PIRSF PIRSF016202 1 351 3.2E-102 T 06-07-2017 IPR007184 Mannoside phosphorylase GTHT12_RS16820 26fc8bd2f53bd0c3eee7f2220ff9ee39 352 Pfam PF04041 beta-1,4-mannooligosaccharide phosphorylase 108 347 3.3E-53 T 06-07-2017 IPR007184 Mannoside phosphorylase GTHT12_RS16820 26fc8bd2f53bd0c3eee7f2220ff9ee39 352 SUPERFAMILY SSF75005 103 341 2.72E-80 T 06-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain GTHT12_RS16820 26fc8bd2f53bd0c3eee7f2220ff9ee39 352 SUPERFAMILY SSF75005 3 50 2.72E-80 T 06-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain GTHT12_RS01505 10d65ea2c690c9fbbf57f12e56ad2e79 456 Gene3D G3DSA:1.20.200.10 135 411 2.1E-100 T 06-07-2017 GTHT12_RS01505 10d65ea2c690c9fbbf57f12e56ad2e79 456 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 4 456 2.9E-226 T 06-07-2017 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GTHT12_RS01505 10d65ea2c690c9fbbf57f12e56ad2e79 456 Gene3D G3DSA:1.10.275.10 2 134 9.0E-59 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal GTHT12_RS01505 10d65ea2c690c9fbbf57f12e56ad2e79 456 PRINTS PR00149 Fumarate lyase superfamily signature 176 194 1.3E-34 T 06-07-2017 IPR000362 Fumarate lyase family GTHT12_RS01505 10d65ea2c690c9fbbf57f12e56ad2e79 456 PRINTS PR00149 Fumarate lyase superfamily signature 267 294 1.3E-34 T 06-07-2017 IPR000362 Fumarate lyase family GTHT12_RS01505 10d65ea2c690c9fbbf57f12e56ad2e79 456 PRINTS PR00149 Fumarate lyase superfamily signature 130 148 1.3E-34 T 06-07-2017 IPR000362 Fumarate lyase family GTHT12_RS01505 10d65ea2c690c9fbbf57f12e56ad2e79 456 PRINTS PR00149 Fumarate lyase superfamily signature 313 329 1.3E-34 T 06-07-2017 IPR000362 Fumarate lyase family GTHT12_RS01505 10d65ea2c690c9fbbf57f12e56ad2e79 456 ProSitePatterns PS00163 Fumarate lyases signature. 313 322 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 GTHT12_RS01505 10d65ea2c690c9fbbf57f12e56ad2e79 456 Pfam PF10415 Fumarase C C-terminus 404 456 5.4E-24 T 06-07-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GTHT12_RS01505 10d65ea2c690c9fbbf57f12e56ad2e79 456 Pfam PF00206 Lyase 11 338 3.5E-113 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal GTHT12_RS01505 10d65ea2c690c9fbbf57f12e56ad2e79 456 PRINTS PR00145 Argininosuccinate lyase family signature 313 329 9.1E-5 T 06-07-2017 GTHT12_RS01505 10d65ea2c690c9fbbf57f12e56ad2e79 456 PRINTS PR00145 Argininosuccinate lyase family signature 171 191 9.1E-5 T 06-07-2017 GTHT12_RS01505 10d65ea2c690c9fbbf57f12e56ad2e79 456 SUPERFAMILY SSF48557 3 456 2.67E-152 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 GTHT12_RS01505 10d65ea2c690c9fbbf57f12e56ad2e79 456 Gene3D G3DSA:1.10.40.30 412 456 4.3E-29 T 06-07-2017 GTHT12_RS01505 10d65ea2c690c9fbbf57f12e56ad2e79 456 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 456 86.311 T 06-07-2017 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GTHT12_RS15865 6e60bee93ccb355dd8efdd3c64ebb631 78 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 75 4.2E-23 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 GTHT12_RS15865 6e60bee93ccb355dd8efdd3c64ebb631 78 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 6.0E-14 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 GTHT12_RS15865 6e60bee93ccb355dd8efdd3c64ebb631 78 PRINTS PR01651 Protein-export SecG membrane protein signature 56 78 6.0E-14 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 GTHT12_RS15865 6e60bee93ccb355dd8efdd3c64ebb631 78 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 6.0E-14 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 GTHT12_RS15865 6e60bee93ccb355dd8efdd3c64ebb631 78 Pfam PF03840 Preprotein translocase SecG subunit 4 75 1.6E-22 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 GTHT12_RS04820 844ae8f1f5e817c1470503438f6ed9e8 224 Gene3D G3DSA:3.40.50.2300 2 121 2.1E-45 T 06-07-2017 GTHT12_RS04820 844ae8f1f5e817c1470503438f6ed9e8 224 Pfam PF00072 Response regulator receiver domain 4 113 3.9E-33 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS04820 844ae8f1f5e817c1470503438f6ed9e8 224 SUPERFAMILY SSF52172 1 166 3.84E-47 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS04820 844ae8f1f5e817c1470503438f6ed9e8 224 SMART SM00448 2 112 1.1E-47 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS04820 844ae8f1f5e817c1470503438f6ed9e8 224 Gene3D G3DSA:1.10.10.10 124 222 6.4E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS04820 844ae8f1f5e817c1470503438f6ed9e8 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 220 1.2E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS04820 844ae8f1f5e817c1470503438f6ed9e8 224 SMART SM00862 145 220 1.2E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS10285 518837920984b3059968786b215f5052 377 SMART SM00345 9 68 3.2E-22 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS10285 518837920984b3059968786b215f5052 377 SUPERFAMILY SSF53822 90 366 7.66E-54 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS10285 518837920984b3059968786b215f5052 377 Gene3D G3DSA:1.10.10.10 3 62 9.8E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS10285 518837920984b3059968786b215f5052 377 Pfam PF13377 Periplasmic binding protein-like domain 201 365 1.7E-24 T 06-07-2017 GTHT12_RS10285 518837920984b3059968786b215f5052 377 Gene3D G3DSA:3.40.50.2300 201 365 1.1E-37 T 06-07-2017 GTHT12_RS10285 518837920984b3059968786b215f5052 377 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 68 4.7E-20 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS10285 518837920984b3059968786b215f5052 377 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 1.7E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS10285 518837920984b3059968786b215f5052 377 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 1.7E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS10285 518837920984b3059968786b215f5052 377 Gene3D G3DSA:3.40.1410.10 63 90 6.3E-4 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain GTHT12_RS10285 518837920984b3059968786b215f5052 377 Gene3D G3DSA:3.40.50.2300 91 200 2.0E-32 T 06-07-2017 GTHT12_RS10285 518837920984b3059968786b215f5052 377 SUPERFAMILY SSF46785 3 72 1.68E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS13600 cc8cdd603e21a84c548777cf7e612c71 179 Pfam PF08279 HTH domain 12 64 3.8E-15 T 06-07-2017 IPR013196 Helix-turn-helix, type 11 GTHT12_RS13600 cc8cdd603e21a84c548777cf7e612c71 179 SUPERFAMILY SSF75500 75 178 9.02E-35 T 06-07-2017 IPR004173 3H domain GO:0036094 GTHT12_RS13600 cc8cdd603e21a84c548777cf7e612c71 179 Gene3D G3DSA:1.10.10.10 3 67 1.4E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS13600 cc8cdd603e21a84c548777cf7e612c71 179 SUPERFAMILY SSF46785 9 67 2.12E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS13600 cc8cdd603e21a84c548777cf7e612c71 179 Pfam PF02829 3H domain 80 176 2.7E-33 T 06-07-2017 IPR004173 3H domain GO:0036094 GTHT12_RS13600 cc8cdd603e21a84c548777cf7e612c71 179 PIRSF PIRSF037847 7 179 6.0E-65 T 06-07-2017 IPR026043 Transcription repressor NadR GTHT12_RS13600 cc8cdd603e21a84c548777cf7e612c71 179 Gene3D G3DSA:3.30.1340.20 74 178 8.2E-40 T 06-07-2017 IPR004173 3H domain GO:0036094 GTHT12_RS13600 cc8cdd603e21a84c548777cf7e612c71 179 ProDom PD469575 TRANSCRIPTION DNA-BINDING REGULATION TRANSCRIPTIONAL REGULATOR REPRESSOR FAMILY BIOTIN REGULATOR 3H 84 177 2.0E-47 T 06-07-2017 IPR004173 3H domain GO:0036094 GTHT12_RS07610 593fe42c8ec8d58db716c75049b5746a 671 Gene3D G3DSA:3.40.50.980 106 280 1.5E-28 T 06-07-2017 GTHT12_RS07610 593fe42c8ec8d58db716c75049b5746a 671 Gene3D G3DSA:3.30.300.30 530 623 1.7E-14 T 06-07-2017 GTHT12_RS07610 593fe42c8ec8d58db716c75049b5746a 671 Pfam PF13193 AMP-binding enzyme C-terminal domain 546 620 4.4E-6 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain GTHT12_RS07610 593fe42c8ec8d58db716c75049b5746a 671 SUPERFAMILY SSF56801 31 653 3.66E-136 T 06-07-2017 GTHT12_RS07610 593fe42c8ec8d58db716c75049b5746a 671 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 46 100 6.0E-13 T 06-07-2017 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 GTHT12_RS07610 593fe42c8ec8d58db716c75049b5746a 671 Gene3D G3DSA:3.40.50.980 281 428 3.1E-16 T 06-07-2017 GTHT12_RS07610 593fe42c8ec8d58db716c75049b5746a 671 Pfam PF00501 AMP-binding enzyme 107 533 1.2E-52 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GTHT12_RS07610 593fe42c8ec8d58db716c75049b5746a 671 ProSitePatterns PS00455 Putative AMP-binding domain signature. 275 286 - T 06-07-2017 IPR020845 AMP-binding, conserved site GTHT12_RS07610 593fe42c8ec8d58db716c75049b5746a 671 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 14 658 3.2E-266 T 06-07-2017 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 GTHT12_RS10755 d768554f4efeb69b2a89d25ba93e30d9 505 SUPERFAMILY SSF53720 12 497 1.13E-181 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10755 d768554f4efeb69b2a89d25ba93e30d9 505 Gene3D G3DSA:3.40.309.10 277 466 4.8E-73 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 GTHT12_RS10755 d768554f4efeb69b2a89d25ba93e30d9 505 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 263 270 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10755 d768554f4efeb69b2a89d25ba93e30d9 505 Pfam PF00171 Aldehyde dehydrogenase family 30 491 9.2E-184 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10755 d768554f4efeb69b2a89d25ba93e30d9 505 Gene3D G3DSA:3.40.605.10 19 276 2.9E-106 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS12635 dfe5424ecdcf45f275e7adb9ab2ba8c6 141 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 63 125 1.1E-18 T 06-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 GTHT12_RS12635 dfe5424ecdcf45f275e7adb9ab2ba8c6 141 SUPERFAMILY SSF46785 3 62 2.05E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12635 dfe5424ecdcf45f275e7adb9ab2ba8c6 141 Gene3D G3DSA:1.10.60.10 74 138 1.4E-25 T 06-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 GTHT12_RS12635 dfe5424ecdcf45f275e7adb9ab2ba8c6 141 Hamap MF_00732 Transcriptional regulator MntR [mntR]. 1 139 45.486 T 06-07-2017 IPR022897 Transcription regulator MntR GTHT12_RS12635 dfe5424ecdcf45f275e7adb9ab2ba8c6 141 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 60 7.1E-25 T 06-07-2017 IPR022687 DTXR-type HTH domain GO:0003677 GTHT12_RS12635 dfe5424ecdcf45f275e7adb9ab2ba8c6 141 Gene3D G3DSA:1.10.10.10 3 73 7.1E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12635 dfe5424ecdcf45f275e7adb9ab2ba8c6 141 SUPERFAMILY SSF47979 63 133 1.8E-19 T 06-07-2017 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 GTHT12_RS12635 dfe5424ecdcf45f275e7adb9ab2ba8c6 141 SMART SM00529 24 123 1.1E-44 T 06-07-2017 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 GTHT12_RS00650 275abde9c64484a4b86f28b6237cd95b 395 Pfam PF03144 Elongation factor Tu domain 2 225 294 1.0E-19 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 GTHT12_RS00650 275abde9c64484a4b86f28b6237cd95b 395 SUPERFAMILY SSF50465 299 394 1.76E-36 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal GTHT12_RS00650 275abde9c64484a4b86f28b6237cd95b 395 SUPERFAMILY SSF50447 205 302 3.73E-31 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain GTHT12_RS00650 275abde9c64484a4b86f28b6237cd95b 395 Pfam PF03143 Elongation factor Tu C-terminal domain 299 393 9.2E-35 T 06-07-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal GTHT12_RS00650 275abde9c64484a4b86f28b6237cd95b 395 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 1.6E-238 T 06-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GTHT12_RS00650 275abde9c64484a4b86f28b6237cd95b 395 SUPERFAMILY SSF52540 9 226 1.93E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00650 275abde9c64484a4b86f28b6237cd95b 395 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 146 3.2E-16 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 GTHT12_RS00650 275abde9c64484a4b86f28b6237cd95b 395 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site GTHT12_RS00650 275abde9c64484a4b86f28b6237cd95b 395 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.1E-25 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GTHT12_RS00650 275abde9c64484a4b86f28b6237cd95b 395 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.1E-25 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GTHT12_RS00650 275abde9c64484a4b86f28b6237cd95b 395 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.1E-25 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GTHT12_RS00650 275abde9c64484a4b86f28b6237cd95b 395 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.1E-25 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GTHT12_RS00650 275abde9c64484a4b86f28b6237cd95b 395 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.1E-25 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GTHT12_RS00650 275abde9c64484a4b86f28b6237cd95b 395 Gene3D G3DSA:3.40.50.300 4 208 1.8E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00650 275abde9c64484a4b86f28b6237cd95b 395 Gene3D G3DSA:2.40.30.10 301 394 8.8E-47 T 06-07-2017 GTHT12_RS00650 275abde9c64484a4b86f28b6237cd95b 395 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 8.3E-63 T 06-07-2017 GTHT12_RS00650 275abde9c64484a4b86f28b6237cd95b 395 Gene3D G3DSA:2.40.30.10 209 299 8.4E-39 T 06-07-2017 GTHT12_RS00650 275abde9c64484a4b86f28b6237cd95b 395 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 395 61.938 T 06-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GTHT12_RS01885 9b7ac53c9c21d8dba770f096c646a2bf 402 Pfam PF13365 Trypsin-like peptidase domain 115 258 2.6E-32 T 06-07-2017 GTHT12_RS01885 9b7ac53c9c21d8dba770f096c646a2bf 402 SMART SM00228 296 385 1.2E-12 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS01885 9b7ac53c9c21d8dba770f096c646a2bf 402 Gene3D G3DSA:2.30.42.10 298 400 1.7E-23 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS01885 9b7ac53c9c21d8dba770f096c646a2bf 402 Pfam PF13180 PDZ domain 296 394 2.7E-19 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS01885 9b7ac53c9c21d8dba770f096c646a2bf 402 SUPERFAMILY SSF50494 79 293 4.26E-56 T 06-07-2017 IPR009003 Peptidase S1, PA clan GTHT12_RS01885 9b7ac53c9c21d8dba770f096c646a2bf 402 SUPERFAMILY SSF50156 280 394 3.02E-20 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS01885 9b7ac53c9c21d8dba770f096c646a2bf 402 Gene3D G3DSA:2.40.10.10 70 183 3.3E-28 T 06-07-2017 GTHT12_RS01885 9b7ac53c9c21d8dba770f096c646a2bf 402 Gene3D G3DSA:2.40.10.10 184 297 6.6E-42 T 06-07-2017 GTHT12_RS01885 9b7ac53c9c21d8dba770f096c646a2bf 402 PRINTS PR00834 HtrA/DegQ protease family signature 189 213 1.6E-39 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GTHT12_RS01885 9b7ac53c9c21d8dba770f096c646a2bf 402 PRINTS PR00834 HtrA/DegQ protease family signature 229 246 1.6E-39 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GTHT12_RS01885 9b7ac53c9c21d8dba770f096c646a2bf 402 PRINTS PR00834 HtrA/DegQ protease family signature 148 168 1.6E-39 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GTHT12_RS01885 9b7ac53c9c21d8dba770f096c646a2bf 402 PRINTS PR00834 HtrA/DegQ protease family signature 342 354 1.6E-39 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GTHT12_RS01885 9b7ac53c9c21d8dba770f096c646a2bf 402 PRINTS PR00834 HtrA/DegQ protease family signature 251 268 1.6E-39 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GTHT12_RS01885 9b7ac53c9c21d8dba770f096c646a2bf 402 PRINTS PR00834 HtrA/DegQ protease family signature 127 139 1.6E-39 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 GTHT12_RS12955 c683a5ac6d4910d0be0fd652413d1de8 251 SMART SM00382 31 226 4.3E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS12955 c683a5ac6d4910d0be0fd652413d1de8 251 Gene3D G3DSA:3.40.50.300 3 228 1.4E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12955 c683a5ac6d4910d0be0fd652413d1de8 251 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS12955 c683a5ac6d4910d0be0fd652413d1de8 251 Pfam PF00005 ABC transporter 22 170 7.3E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS12955 c683a5ac6d4910d0be0fd652413d1de8 251 SUPERFAMILY SSF52540 5 228 6.79E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05015 a77b4945cfa6c5a58d7352c4a130756b 516 Pfam PF00005 ABC transporter 274 424 1.7E-14 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS05015 a77b4945cfa6c5a58d7352c4a130756b 516 Pfam PF00005 ABC transporter 19 172 1.9E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS05015 a77b4945cfa6c5a58d7352c4a130756b 516 SMART SM00382 280 464 0.004 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS05015 a77b4945cfa6c5a58d7352c4a130756b 516 SMART SM00382 28 228 5.7E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS05015 a77b4945cfa6c5a58d7352c4a130756b 516 ProSitePatterns PS00211 ABC transporters family signature. 397 411 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS05015 a77b4945cfa6c5a58d7352c4a130756b 516 SUPERFAMILY SSF52540 4 230 1.03E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05015 a77b4945cfa6c5a58d7352c4a130756b 516 Gene3D G3DSA:3.40.50.300 273 492 1.8E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05015 a77b4945cfa6c5a58d7352c4a130756b 516 Gene3D G3DSA:3.40.50.300 4 233 4.9E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05015 a77b4945cfa6c5a58d7352c4a130756b 516 SUPERFAMILY SSF52540 274 491 8.33E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06830 3dd1f4b6425fa2e286ea2484d4f87ae3 281 SUPERFAMILY SSF48179 185 281 7.4E-33 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GTHT12_RS06830 3dd1f4b6425fa2e286ea2484d4f87ae3 281 PIRSF PIRSF000105 1 281 9.6E-98 T 06-07-2017 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 GTHT12_RS06830 3dd1f4b6425fa2e286ea2484d4f87ae3 281 SUPERFAMILY SSF51735 3 183 2.51E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS06830 3dd1f4b6425fa2e286ea2484d4f87ae3 281 Gene3D G3DSA:3.40.50.720 3 187 3.6E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS06830 3dd1f4b6425fa2e286ea2484d4f87ae3 281 Gene3D G3DSA:1.10.1040.10 188 281 1.3E-35 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 GTHT12_RS06830 3dd1f4b6425fa2e286ea2484d4f87ae3 281 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 183 5.9E-68 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 GTHT12_RS06830 3dd1f4b6425fa2e286ea2484d4f87ae3 281 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 281 1.0E-32 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 GTHT12_RS13130 f0ff8911fe55a4b029dde5feebe5905c 220 PRINTS PR00773 GrpE protein signature 172 187 8.3E-32 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 GTHT12_RS13130 f0ff8911fe55a4b029dde5feebe5905c 220 PRINTS PR00773 GrpE protein signature 90 106 8.3E-32 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 GTHT12_RS13130 f0ff8911fe55a4b029dde5feebe5905c 220 PRINTS PR00773 GrpE protein signature 199 218 8.3E-32 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 GTHT12_RS13130 f0ff8911fe55a4b029dde5feebe5905c 220 PRINTS PR00773 GrpE protein signature 118 133 8.3E-32 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 GTHT12_RS13130 f0ff8911fe55a4b029dde5feebe5905c 220 ProSitePatterns PS01071 grpE protein signature. 175 218 - T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 GTHT12_RS13130 f0ff8911fe55a4b029dde5feebe5905c 220 Hamap MF_01151 Protein GrpE [grpE]. 29 220 22.405 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 GTHT12_RS13130 f0ff8911fe55a4b029dde5feebe5905c 220 SUPERFAMILY SSF51064 165 220 5.36E-20 T 06-07-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 GTHT12_RS13130 f0ff8911fe55a4b029dde5feebe5905c 220 Gene3D G3DSA:3.90.20.20 65 162 9.7E-33 T 06-07-2017 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 GTHT12_RS13130 f0ff8911fe55a4b029dde5feebe5905c 220 SUPERFAMILY SSF58014 68 164 5.23E-29 T 06-07-2017 GTHT12_RS13130 f0ff8911fe55a4b029dde5feebe5905c 220 Gene3D G3DSA:2.30.22.10 164 220 9.9E-28 T 06-07-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 GTHT12_RS13130 f0ff8911fe55a4b029dde5feebe5905c 220 Pfam PF01025 GrpE 59 220 2.2E-60 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 GTHT12_RS11990 772a7b6bc25411ccbeaf1efa1555ddb9 305 SUPERFAMILY SSF51366 48 207 2.35E-6 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 GTHT12_RS11990 772a7b6bc25411ccbeaf1efa1555ddb9 305 Gene3D G3DSA:3.20.20.70 28 207 2.1E-8 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS07385 e34066984dec1a85d2211408e58ea09a 450 Gene3D G3DSA:3.40.640.10 66 337 1.7E-86 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS07385 e34066984dec1a85d2211408e58ea09a 450 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 249 286 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GTHT12_RS07385 e34066984dec1a85d2211408e58ea09a 450 PIRSF PIRSF000521 20 449 2.0E-38 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GTHT12_RS07385 e34066984dec1a85d2211408e58ea09a 450 Gene3D G3DSA:3.90.1150.10 9 65 5.5E-43 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS07385 e34066984dec1a85d2211408e58ea09a 450 Gene3D G3DSA:3.90.1150.10 340 449 5.5E-43 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS07385 e34066984dec1a85d2211408e58ea09a 450 Pfam PF00202 Aminotransferase class-III 26 446 1.4E-113 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GTHT12_RS07385 e34066984dec1a85d2211408e58ea09a 450 SUPERFAMILY SSF53383 18 447 1.39E-126 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS13495 0744638514256bf0e55590b8aa35b32d 302 Pfam PF01545 Cation efflux family 17 211 7.1E-45 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 GTHT12_RS13495 0744638514256bf0e55590b8aa35b32d 302 Gene3D G3DSA:3.30.70.1350 217 297 3.5E-18 T 06-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain GTHT12_RS13495 0744638514256bf0e55590b8aa35b32d 302 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 13 297 9.6E-74 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 GTHT12_RS13495 0744638514256bf0e55590b8aa35b32d 302 SUPERFAMILY SSF160240 220 297 1.83E-17 T 06-07-2017 GTHT12_RS13495 0744638514256bf0e55590b8aa35b32d 302 SUPERFAMILY SSF161111 9 216 1.57E-54 T 06-07-2017 GTHT12_RS13495 0744638514256bf0e55590b8aa35b32d 302 Gene3D G3DSA:1.20.1510.10 13 212 4.7E-47 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain GTHT12_RS13495 0744638514256bf0e55590b8aa35b32d 302 Pfam PF16916 Dimerisation domain of Zinc Transporter 220 296 2.7E-20 T 06-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain GTHT12_RS05555 981596a3521dd31f26e67325a545d2ec 555 Gene3D G3DSA:3.60.15.10 6 255 9.0E-79 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS05555 981596a3521dd31f26e67325a545d2ec 555 SUPERFAMILY SSF56281 11 422 3.8E-94 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS05555 981596a3521dd31f26e67325a545d2ec 555 SMART SM00849 21 215 3.1E-24 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS05555 981596a3521dd31f26e67325a545d2ec 555 PIRSF PIRSF004803 1 555 1.4E-245 T 06-07-2017 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 GTHT12_RS05555 981596a3521dd31f26e67325a545d2ec 555 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 364 392 - T 06-07-2017 IPR001587 Ribonuclease J, conserved site GTHT12_RS05555 981596a3521dd31f26e67325a545d2ec 555 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 10 553 7.3E-229 T 06-07-2017 IPR004613 Ribonuclease J GO:0003723|GO:0046872 GTHT12_RS05555 981596a3521dd31f26e67325a545d2ec 555 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 361 405 3.7E-10 T 06-07-2017 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain GTHT12_RS05555 981596a3521dd31f26e67325a545d2ec 555 Pfam PF00753 Metallo-beta-lactamase superfamily 20 167 8.8E-14 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS05555 981596a3521dd31f26e67325a545d2ec 555 Hamap MF_01491 Ribonuclease J [rnj]. 4 555 47.762 T 06-07-2017 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 GTHT12_RS04340 009b8e554ef5eb5f2ba4481c931b7fb2 222 Pfam PF03741 Integral membrane protein TerC family 12 180 1.2E-42 T 06-07-2017 IPR005496 Integral membrane protein TerC GO:0016021 GTHT12_RS04340 009b8e554ef5eb5f2ba4481c931b7fb2 222 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 9 181 7.3E-69 T 06-07-2017 IPR022301 Integral membrane protein YjbE GTHT12_RS09410 c02de29415b64b732bbaf2e87f07e408 500 SUPERFAMILY SSF52317 258 452 9.49E-33 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS09410 c02de29415b64b732bbaf2e87f07e408 500 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 497 182.507 T 06-07-2017 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 GTHT12_RS09410 c02de29415b64b732bbaf2e87f07e408 500 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 257 443 9.8E-51 T 06-07-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 GTHT12_RS09410 c02de29415b64b732bbaf2e87f07e408 500 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 230 8.7E-28 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain GTHT12_RS09410 c02de29415b64b732bbaf2e87f07e408 500 SUPERFAMILY SSF52540 7 242 3.84E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS09410 c02de29415b64b732bbaf2e87f07e408 500 Gene3D G3DSA:3.40.50.300 7 240 2.7E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS09410 c02de29415b64b732bbaf2e87f07e408 500 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 7 488 6.4E-164 T 06-07-2017 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 GTHT12_RS09410 c02de29415b64b732bbaf2e87f07e408 500 Gene3D G3DSA:3.40.50.880 256 454 5.4E-29 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS01330 59a5c19eef20f3c3aa9595e1ea16056f 721 SUPERFAMILY SSF158832 6 315 1.31E-117 T 06-07-2017 GTHT12_RS01330 59a5c19eef20f3c3aa9595e1ea16056f 721 Pfam PF00575 S1 RNA binding domain 646 716 1.1E-17 T 06-07-2017 IPR003029 S1 domain GO:0003676 GTHT12_RS01330 59a5c19eef20f3c3aa9595e1ea16056f 721 SMART SM00732 320 418 1.3E-37 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 GTHT12_RS01330 59a5c19eef20f3c3aa9595e1ea16056f 721 Gene3D G3DSA:2.40.50.140 640 716 8.8E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS01330 59a5c19eef20f3c3aa9595e1ea16056f 721 Gene3D G3DSA:1.10.3500.10 445 492 4.3E-99 T 06-07-2017 IPR023323 Tex-like domain GTHT12_RS01330 59a5c19eef20f3c3aa9595e1ea16056f 721 Gene3D G3DSA:1.10.3500.10 112 316 4.3E-99 T 06-07-2017 IPR023323 Tex-like domain GTHT12_RS01330 59a5c19eef20f3c3aa9595e1ea16056f 721 SMART SM00316 646 717 7.8E-23 T 06-07-2017 IPR022967 RNA-binding domain, S1 GTHT12_RS01330 59a5c19eef20f3c3aa9595e1ea16056f 721 Gene3D G3DSA:1.10.150.310 493 627 7.2E-42 T 06-07-2017 IPR023097 Tex RuvX-like domain GTHT12_RS01330 59a5c19eef20f3c3aa9595e1ea16056f 721 Pfam PF09371 Tex-like protein N-terminal domain 11 195 2.5E-73 T 06-07-2017 IPR018974 Tex-like protein, N-terminal GTHT12_RS01330 59a5c19eef20f3c3aa9595e1ea16056f 721 SUPERFAMILY SSF53098 316 463 2.09E-51 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS01330 59a5c19eef20f3c3aa9595e1ea16056f 721 Pfam PF16921 Tex protein YqgF-like domain 320 445 2.2E-57 T 06-07-2017 IPR032639 Tex protein, YqgF-like domain GTHT12_RS01330 59a5c19eef20f3c3aa9595e1ea16056f 721 SUPERFAMILY SSF47781 464 550 1.02E-25 T 06-07-2017 IPR010994 RuvA domain 2-like GTHT12_RS01330 59a5c19eef20f3c3aa9595e1ea16056f 721 SUPERFAMILY SSF47781 554 629 9.12E-16 T 06-07-2017 IPR010994 RuvA domain 2-like GTHT12_RS01330 59a5c19eef20f3c3aa9595e1ea16056f 721 Pfam PF12836 Helix-hairpin-helix motif 485 549 8.4E-26 T 06-07-2017 GTHT12_RS01330 59a5c19eef20f3c3aa9595e1ea16056f 721 Gene3D G3DSA:3.30.420.140 320 444 8.5E-54 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 GTHT12_RS01330 59a5c19eef20f3c3aa9595e1ea16056f 721 SUPERFAMILY SSF50249 632 717 2.54E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS01330 59a5c19eef20f3c3aa9595e1ea16056f 721 Gene3D G3DSA:1.10.10.650 4 111 1.6E-41 T 06-07-2017 IPR023319 Tex-like protein, HTH domain GTHT12_RS16070 9c1c03db2a011a005d2805ae4500f216 172 Pfam PF13411 MerR HTH family regulatory protein 5 52 3.5E-8 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS16070 9c1c03db2a011a005d2805ae4500f216 172 SUPERFAMILY SSF46955 4 105 1.83E-9 T 06-07-2017 IPR009061 Putative DNA-binding domain GTHT12_RS16070 9c1c03db2a011a005d2805ae4500f216 172 Gene3D G3DSA:1.10.1660.10 4 147 2.1E-7 T 06-07-2017 GTHT12_RS16070 9c1c03db2a011a005d2805ae4500f216 172 Hamap MF_01170 Chromosome-anchoring protein RacA [racA]. 3 170 22.817 T 06-07-2017 IPR023522 Chromosome-anchoring protein RacA GTHT12_RS00270 7ad77179dced329308e551dc1fe925b8 315 Gene3D G3DSA:3.40.50.2020 5 163 3.7E-78 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS00270 7ad77179dced329308e551dc1fe925b8 315 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 132 147 - T 06-07-2017 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 GTHT12_RS00270 7ad77179dced329308e551dc1fe925b8 315 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 9 315 4.6E-131 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 GTHT12_RS00270 7ad77179dced329308e551dc1fe925b8 315 Pfam PF14572 Phosphoribosyl synthetase-associated domain 206 314 2.2E-24 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 GTHT12_RS00270 7ad77179dced329308e551dc1fe925b8 315 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 8 124 5.2E-52 T 06-07-2017 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 GTHT12_RS00270 7ad77179dced329308e551dc1fe925b8 315 Gene3D G3DSA:3.40.50.2020 164 288 1.3E-57 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS00270 7ad77179dced329308e551dc1fe925b8 315 SUPERFAMILY SSF53271 73 306 3.37E-66 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS00270 7ad77179dced329308e551dc1fe925b8 315 SMART SM01400 8 124 3.3E-82 T 06-07-2017 GTHT12_RS00270 7ad77179dced329308e551dc1fe925b8 315 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 8 315 51.781 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 GTHT12_RS00565 e0e3a4aa46be99d46c29b9f7cc713a6a 246 SMART SM00967 4 78 1.1E-23 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 GTHT12_RS00565 e0e3a4aa46be99d46c29b9f7cc713a6a 246 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 1 241 1.2E-81 T 06-07-2017 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 GTHT12_RS00565 e0e3a4aa46be99d46c29b9f7cc713a6a 246 Gene3D G3DSA:3.30.1330.30 3 73 4.4E-24 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like GTHT12_RS00565 e0e3a4aa46be99d46c29b9f7cc713a6a 246 Gene3D G3DSA:3.40.1280.10 89 241 5.6E-54 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal GTHT12_RS00565 e0e3a4aa46be99d46c29b9f7cc713a6a 246 SUPERFAMILY SSF55315 2 75 5.89E-19 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like GTHT12_RS00565 e0e3a4aa46be99d46c29b9f7cc713a6a 246 Pfam PF00588 SpoU rRNA Methylase family 95 235 1.9E-40 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 GTHT12_RS00565 e0e3a4aa46be99d46c29b9f7cc713a6a 246 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 4 77 1.6E-23 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 GTHT12_RS00565 e0e3a4aa46be99d46c29b9f7cc713a6a 246 SUPERFAMILY SSF75217 66 242 9.81E-51 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases GTHT12_RS06270 17ac59746f3292257ced90dd5587c900 95 Gene3D G3DSA:3.40.1690.10 6 84 3.8E-24 T 06-07-2017 IPR029025 Type III secretion system substrate exporter, C-terminal GTHT12_RS06270 17ac59746f3292257ced90dd5587c900 95 SUPERFAMILY SSF160544 6 84 6.8E-23 T 06-07-2017 IPR029025 Type III secretion system substrate exporter, C-terminal GTHT12_RS06270 17ac59746f3292257ced90dd5587c900 95 Pfam PF01312 FlhB HrpN YscU SpaS Family 8 79 1.5E-16 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 GTHT12_RS00670 7b750cec8983252dc8a69344936f8c23 95 SUPERFAMILY SSF54189 2 90 1.69E-32 T 06-07-2017 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00670 7b750cec8983252dc8a69344936f8c23 95 Gene3D G3DSA:3.30.70.330 2 94 3.1E-34 T 06-07-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 GTHT12_RS00670 7b750cec8983252dc8a69344936f8c23 95 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 95 21.413 T 06-07-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00670 7b750cec8983252dc8a69344936f8c23 95 ProSitePatterns PS00050 Ribosomal protein L23 signature. 77 92 - T 06-07-2017 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00670 7b750cec8983252dc8a69344936f8c23 95 Pfam PF00276 Ribosomal protein L23 6 88 1.4E-32 T 06-07-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 GTHT12_RS15305 c824c229ab6fc16bfaf9cd00aeba17ad 166 SUPERFAMILY SSF46785 3 61 1.28E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS15305 c824c229ab6fc16bfaf9cd00aeba17ad 166 Pfam PF01037 Lrp/AsnC ligand binding domain 73 144 1.4E-16 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain GTHT12_RS15305 c824c229ab6fc16bfaf9cd00aeba17ad 166 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 49 5.2E-5 T 06-07-2017 GTHT12_RS15305 c824c229ab6fc16bfaf9cd00aeba17ad 166 Gene3D G3DSA:1.10.10.10 1 54 4.4E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS15305 c824c229ab6fc16bfaf9cd00aeba17ad 166 SMART SM00344 3 114 5.6E-7 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 GTHT12_RS15305 c824c229ab6fc16bfaf9cd00aeba17ad 166 Gene3D G3DSA:3.30.70.920 68 147 9.7E-29 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain GTHT12_RS15305 c824c229ab6fc16bfaf9cd00aeba17ad 166 SUPERFAMILY SSF54909 66 147 5.23E-19 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel GTHT12_RS01065 0d6a448dd3004e8316d399ec97b68472 335 Pfam PF01032 FecCD transport family 19 327 2.0E-80 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 GTHT12_RS01065 0d6a448dd3004e8316d399ec97b68472 335 Gene3D G3DSA:1.10.3470.10 9 330 4.5E-90 T 06-07-2017 IPR029022 ABC transporter, BtuC-like GTHT12_RS01065 0d6a448dd3004e8316d399ec97b68472 335 SUPERFAMILY SSF81345 9 327 5.89E-76 T 06-07-2017 IPR029022 ABC transporter, BtuC-like GTHT12_RS03695 d14b0f1c3eee7d7d340338bbc80add8d 480 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 5 464 2.8E-133 T 06-07-2017 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 GTHT12_RS03695 d14b0f1c3eee7d7d340338bbc80add8d 480 SUPERFAMILY SSF54373 302 410 9.32E-33 T 06-07-2017 GTHT12_RS03695 d14b0f1c3eee7d7d340338bbc80add8d 480 Gene3D G3DSA:3.40.50.720 407 473 1.2E-7 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS03695 d14b0f1c3eee7d7d340338bbc80add8d 480 Gene3D G3DSA:3.40.50.720 7 94 1.2E-7 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS03695 d14b0f1c3eee7d7d340338bbc80add8d 480 Gene3D G3DSA:1.10.3110.10 114 210 1.5E-32 T 06-07-2017 GTHT12_RS03695 d14b0f1c3eee7d7d340338bbc80add8d 480 SUPERFAMILY SSF51905 426 463 4.75E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS03695 d14b0f1c3eee7d7d340338bbc80add8d 480 SUPERFAMILY SSF51905 1 321 4.75E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS03695 d14b0f1c3eee7d7d340338bbc80add8d 480 Pfam PF01593 Flavin containing amine oxidoreductase 15 460 9.5E-70 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 GTHT12_RS03695 d14b0f1c3eee7d7d340338bbc80add8d 480 Gene3D G3DSA:3.90.660.20 238 406 7.7E-47 T 06-07-2017 IPR027418 Protoporphyrinogen oxidase, C-terminal domain KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 GTHT12_RS07590 621b12b89fe866a59463cbe9025f7f33 208 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 197 1.6E-65 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 GTHT12_RS07590 621b12b89fe866a59463cbe9025f7f33 208 Gene3D G3DSA:3.40.50.1240 3 204 8.0E-65 T 06-07-2017 IPR029033 Histidine phosphatase superfamily GTHT12_RS07590 621b12b89fe866a59463cbe9025f7f33 208 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 7 16 - T 06-07-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 GTHT12_RS07590 621b12b89fe866a59463cbe9025f7f33 208 PIRSF PIRSF000709 2 196 3.4E-23 T 06-07-2017 GTHT12_RS07590 621b12b89fe866a59463cbe9025f7f33 208 SMART SM00855 4 158 1.6E-24 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 GTHT12_RS07590 621b12b89fe866a59463cbe9025f7f33 208 SUPERFAMILY SSF53254 1 203 4.45E-65 T 06-07-2017 IPR029033 Histidine phosphatase superfamily GTHT12_RS01520 71259f5f696ec620cf4ed07eebc25ab7 387 Pfam PF01882 Protein of unknown function DUF58 192 265 1.4E-20 T 06-07-2017 IPR002881 Domain of unknown function DUF58 GTHT12_RS05395 628695c3b7298a2ac2521605afbeb383 427 SUPERFAMILY SSF51230 2 94 1.27E-28 T 06-07-2017 IPR011053 Single hybrid motif GTHT12_RS05395 628695c3b7298a2ac2521605afbeb383 427 Pfam PF02817 e3 binding domain 123 156 8.6E-12 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS05395 628695c3b7298a2ac2521605afbeb383 427 SUPERFAMILY SSF52777 199 425 2.4E-84 T 06-07-2017 GTHT12_RS05395 628695c3b7298a2ac2521605afbeb383 427 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 3 426 3.6E-178 T 06-07-2017 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 GTHT12_RS05395 628695c3b7298a2ac2521605afbeb383 427 Gene3D G3DSA:4.10.320.10 117 166 9.4E-16 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS05395 628695c3b7298a2ac2521605afbeb383 427 Gene3D G3DSA:3.30.559.10 194 425 6.0E-86 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 GTHT12_RS05395 628695c3b7298a2ac2521605afbeb383 427 SUPERFAMILY SSF47005 116 161 3.53E-9 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS05395 628695c3b7298a2ac2521605afbeb383 427 Gene3D G3DSA:2.40.50.100 3 93 5.8E-32 T 06-07-2017 GTHT12_RS05395 628695c3b7298a2ac2521605afbeb383 427 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 GTHT12_RS05395 628695c3b7298a2ac2521605afbeb383 427 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 199 425 5.1E-80 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS05395 628695c3b7298a2ac2521605afbeb383 427 Pfam PF00364 Biotin-requiring enzyme 3 75 3.9E-24 T 06-07-2017 IPR000089 Biotin/lipoyl attachment GTHT12_RS14935 b4f7b20b5feaa01d08a98d0251937f6a 387 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 98 106 - T 06-07-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 GTHT12_RS14935 b4f7b20b5feaa01d08a98d0251937f6a 387 SUPERFAMILY SSF51161 284 359 5.57E-12 T 06-07-2017 IPR011004 Trimeric LpxA-like GTHT12_RS14935 b4f7b20b5feaa01d08a98d0251937f6a 387 SUPERFAMILY SSF53448 306 323 1.02E-86 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS14935 b4f7b20b5feaa01d08a98d0251937f6a 387 SUPERFAMILY SSF53448 2 262 1.02E-86 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS14935 b4f7b20b5feaa01d08a98d0251937f6a 387 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 11 30 - T 06-07-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 GTHT12_RS14935 b4f7b20b5feaa01d08a98d0251937f6a 387 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 2 375 49.316 T 06-07-2017 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 GTHT12_RS14935 b4f7b20b5feaa01d08a98d0251937f6a 387 Gene3D G3DSA:3.90.550.10 306 348 2.3E-86 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS14935 b4f7b20b5feaa01d08a98d0251937f6a 387 Gene3D G3DSA:3.90.550.10 6 269 2.3E-86 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS14935 b4f7b20b5feaa01d08a98d0251937f6a 387 Pfam PF00483 Nucleotidyl transferase 7 260 1.5E-71 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 GTHT12_RS14935 b4f7b20b5feaa01d08a98d0251937f6a 387 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 189 199 - T 06-07-2017 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 GTHT12_RS14935 b4f7b20b5feaa01d08a98d0251937f6a 387 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 5 356 1.4E-146 T 06-07-2017 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 GTHT12_RS00110 584333de720cd361628a4a50e8584491 559 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 3.4E-5 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS00110 584333de720cd361628a4a50e8584491 559 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 3.4E-5 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS00110 584333de720cd361628a4a50e8584491 559 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 234 359 2.0E-17 T 06-07-2017 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 GTHT12_RS00110 584333de720cd361628a4a50e8584491 559 Pfam PF13177 DNA polymerase III, delta subunit 20 178 3.6E-46 T 06-07-2017 GTHT12_RS00110 584333de720cd361628a4a50e8584491 559 Gene3D G3DSA:1.20.272.10 246 361 1.1E-16 T 06-07-2017 GTHT12_RS00110 584333de720cd361628a4a50e8584491 559 Gene3D G3DSA:3.40.50.300 15 166 1.9E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00110 584333de720cd361628a4a50e8584491 559 SMART SM00382 37 179 1.7E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS00110 584333de720cd361628a4a50e8584491 559 SUPERFAMILY SSF48019 246 361 4.93E-27 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 GTHT12_RS00110 584333de720cd361628a4a50e8584491 559 Gene3D G3DSA:1.10.8.60 167 243 1.1E-34 T 06-07-2017 GTHT12_RS00110 584333de720cd361628a4a50e8584491 559 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 358 4.8E-143 T 06-07-2017 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 GTHT12_RS00110 584333de720cd361628a4a50e8584491 559 SUPERFAMILY SSF52540 31 223 2.22E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01235 9b6225588ed6e31bcd79fae75982f704 659 SUPERFAMILY SSF53649 254 645 1.64E-83 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 GTHT12_RS01235 9b6225588ed6e31bcd79fae75982f704 659 PIRSF PIRSF005091 2 630 1.1E-194 T 06-07-2017 IPR012160 Lipoteichoic acid synthase-like GTHT12_RS01235 9b6225588ed6e31bcd79fae75982f704 659 Pfam PF00884 Sulfatase 256 546 7.7E-39 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 GTHT12_RS01235 9b6225588ed6e31bcd79fae75982f704 659 Gene3D G3DSA:3.40.720.10 256 559 3.2E-41 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 GTHT12_RS04995 e72244d2a1f48d4363665bbef802c28d 590 Pfam PF02310 B12 binding domain 9 122 1.1E-22 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 GTHT12_RS04995 e72244d2a1f48d4363665bbef802c28d 590 Pfam PF13311 Protein of unknown function (DUF4080) 371 552 4.2E-51 T 06-07-2017 IPR025288 Domain of unknown function DUF4080 GTHT12_RS04995 e72244d2a1f48d4363665bbef802c28d 590 Gene3D G3DSA:3.40.50.280 40 100 1.9E-4 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 GTHT12_RS04995 e72244d2a1f48d4363665bbef802c28d 590 Pfam PF04055 Radical SAM superfamily 180 344 1.2E-14 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 GTHT12_RS04995 e72244d2a1f48d4363665bbef802c28d 590 SUPERFAMILY SSF52242 41 149 1.67E-11 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 GTHT12_RS04995 e72244d2a1f48d4363665bbef802c28d 590 Gene3D G3DSA:3.80.30.20 177 370 1.4E-30 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe GTHT12_RS04995 e72244d2a1f48d4363665bbef802c28d 590 SMART SM00729 176 379 2.0E-23 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 GTHT12_RS04995 e72244d2a1f48d4363665bbef802c28d 590 SUPERFAMILY SSF102114 159 380 5.1E-40 T 06-07-2017 GTHT12_RS12820 649f91d915afb32157a67434f7f63184 317 Pfam PF00480 ROK family 6 313 5.3E-75 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 GTHT12_RS12820 649f91d915afb32157a67434f7f63184 317 Gene3D G3DSA:3.30.420.40 143 297 3.4E-56 T 06-07-2017 GTHT12_RS12820 649f91d915afb32157a67434f7f63184 317 SUPERFAMILY SSF53067 4 315 2.74E-71 T 06-07-2017 GTHT12_RS12820 649f91d915afb32157a67434f7f63184 317 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 6 312 3.4E-115 T 06-07-2017 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 GTHT12_RS12820 649f91d915afb32157a67434f7f63184 317 Gene3D G3DSA:3.30.420.40 3 142 6.4E-50 T 06-07-2017 GTHT12_RS12820 649f91d915afb32157a67434f7f63184 317 ProSitePatterns PS01125 ROK family signature. 138 165 - T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 GTHT12_RS03385 0d509853773959190b88c4ca78ea9fa7 148 Pfam PF00571 CBS domain 74 124 5.3E-11 T 06-07-2017 IPR000644 CBS domain GTHT12_RS03385 0d509853773959190b88c4ca78ea9fa7 148 Pfam PF00571 CBS domain 9 59 1.5E-16 T 06-07-2017 IPR000644 CBS domain GTHT12_RS03385 0d509853773959190b88c4ca78ea9fa7 148 Gene3D G3DSA:3.10.580.10 8 125 3.4E-39 T 06-07-2017 GTHT12_RS03385 0d509853773959190b88c4ca78ea9fa7 148 SUPERFAMILY SSF54631 8 124 3.03E-37 T 06-07-2017 GTHT12_RS03385 0d509853773959190b88c4ca78ea9fa7 148 SMART SM00116 81 128 8.2E-13 T 06-07-2017 IPR000644 CBS domain GTHT12_RS03385 0d509853773959190b88c4ca78ea9fa7 148 SMART SM00116 16 63 3.3E-15 T 06-07-2017 IPR000644 CBS domain GTHT12_RS02180 56652f52d62c591a0a89faff91de2865 133 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 GTHT12_RS02180 56652f52d62c591a0a89faff91de2865 133 Pfam PF00293 NUDIX domain 7 120 2.3E-19 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 GTHT12_RS02180 56652f52d62c591a0a89faff91de2865 133 SUPERFAMILY SSF55811 2 128 2.98E-36 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 GTHT12_RS02180 56652f52d62c591a0a89faff91de2865 133 Gene3D G3DSA:3.90.79.10 4 129 1.8E-34 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 GTHT12_RS02180 56652f52d62c591a0a89faff91de2865 133 PRINTS PR00502 NUDIX hydrolase family signature 48 63 2.4E-8 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 GTHT12_RS02180 56652f52d62c591a0a89faff91de2865 133 PRINTS PR00502 NUDIX hydrolase family signature 34 48 2.4E-8 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 GTHT12_RS17660 b000be50fcd92d7f569370ed3b951407 392 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 GTHT12_RS17660 b000be50fcd92d7f569370ed3b951407 392 Gene3D G3DSA:3.40.47.10 143 193 1.0E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS17660 b000be50fcd92d7f569370ed3b951407 392 Gene3D G3DSA:3.40.47.10 277 392 1.0E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS17660 b000be50fcd92d7f569370ed3b951407 392 PIRSF PIRSF000429 1 392 1.8E-122 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 GTHT12_RS17660 b000be50fcd92d7f569370ed3b951407 392 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 GTHT12_RS17660 b000be50fcd92d7f569370ed3b951407 392 SUPERFAMILY SSF53901 4 270 1.83E-88 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS17660 b000be50fcd92d7f569370ed3b951407 392 Pfam PF02803 Thiolase, C-terminal domain 271 391 3.1E-43 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 GTHT12_RS17660 b000be50fcd92d7f569370ed3b951407 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 1.2E-140 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 GTHT12_RS17660 b000be50fcd92d7f569370ed3b951407 392 Pfam PF00108 Thiolase, N-terminal domain 5 263 4.0E-98 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 GTHT12_RS17660 b000be50fcd92d7f569370ed3b951407 392 Gene3D G3DSA:3.40.47.10 194 276 6.0E-73 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS17660 b000be50fcd92d7f569370ed3b951407 392 Gene3D G3DSA:3.40.47.10 5 123 6.0E-73 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS17660 b000be50fcd92d7f569370ed3b951407 392 SUPERFAMILY SSF53901 271 391 2.46E-36 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS17660 b000be50fcd92d7f569370ed3b951407 392 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 GTHT12_RS18090 aa41d7c0aeea038970d49f5595f0cb89 159 SUPERFAMILY SSF75217 3 157 6.28E-59 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases GTHT12_RS18090 aa41d7c0aeea038970d49f5595f0cb89 159 Pfam PF02590 Predicted SPOUT methyltransferase 2 158 2.2E-59 T 06-07-2017 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS18090 aa41d7c0aeea038970d49f5595f0cb89 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 1 159 5.8E-65 T 06-07-2017 IPR016051 Ribosomal RNA large subunit methyltransferase H GO:0005737|GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS18090 aa41d7c0aeea038970d49f5595f0cb89 159 PIRSF PIRSF004505 1 159 5.4E-54 T 06-07-2017 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS18090 aa41d7c0aeea038970d49f5595f0cb89 159 Gene3D G3DSA:3.40.1280.10 2 159 5.8E-63 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal GTHT12_RS18090 aa41d7c0aeea038970d49f5595f0cb89 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 30.656 T 06-07-2017 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS17505 91747ad4afda40327e859ad2e4b6a2a8 236 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 15 231 2.1E-46 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 GTHT12_RS17505 91747ad4afda40327e859ad2e4b6a2a8 236 SUPERFAMILY SSF81336 71 228 3.27E-40 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 GTHT12_RS17505 91747ad4afda40327e859ad2e4b6a2a8 236 Pfam PF00119 ATP synthase A chain 20 228 1.2E-59 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 GTHT12_RS17505 91747ad4afda40327e859ad2e4b6a2a8 236 Gene3D G3DSA:1.20.120.220 72 234 4.5E-45 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 GTHT12_RS17505 91747ad4afda40327e859ad2e4b6a2a8 236 ProSitePatterns PS00449 ATP synthase a subunit signature. 165 174 - T 06-07-2017 IPR023011 ATPase, F0 complex, subunit A, active site Reactome: R-HSA-163210 GTHT12_RS17505 91747ad4afda40327e859ad2e4b6a2a8 236 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 235 13.602 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 GTHT12_RS17505 91747ad4afda40327e859ad2e4b6a2a8 236 PRINTS PR00123 ATP synthase A subunit signature 162 184 7.0E-18 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 GTHT12_RS17505 91747ad4afda40327e859ad2e4b6a2a8 236 PRINTS PR00123 ATP synthase A subunit signature 146 161 7.0E-18 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 GTHT12_RS17505 91747ad4afda40327e859ad2e4b6a2a8 236 PRINTS PR00123 ATP synthase A subunit signature 78 94 7.0E-18 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 GTHT12_RS17505 91747ad4afda40327e859ad2e4b6a2a8 236 PRINTS PR00123 ATP synthase A subunit signature 215 230 7.0E-18 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 GTHT12_RS10495 1fb87c974550cd37e102623cfdac9138 258 Pfam PF01614 Bacterial transcriptional regulator 124 246 5.0E-41 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal GTHT12_RS10495 1fb87c974550cd37e102623cfdac9138 258 SUPERFAMILY SSF46785 4 77 1.09E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS10495 1fb87c974550cd37e102623cfdac9138 258 Pfam PF09339 IclR helix-turn-helix domain 6 57 7.6E-18 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 GTHT12_RS10495 1fb87c974550cd37e102623cfdac9138 258 SUPERFAMILY SSF55781 62 250 1.02E-51 T 06-07-2017 IPR029016 GAF domain-like GTHT12_RS10495 1fb87c974550cd37e102623cfdac9138 258 Gene3D G3DSA:3.30.450.40 76 252 2.4E-57 T 06-07-2017 IPR029016 GAF domain-like GTHT12_RS10495 1fb87c974550cd37e102623cfdac9138 258 SMART SM00346 4 94 5.3E-34 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 GTHT12_RS10495 1fb87c974550cd37e102623cfdac9138 258 Gene3D G3DSA:1.10.10.10 4 75 8.4E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS18120 13140ee351a3f8760c9d772df958dd55 609 Gene3D G3DSA:1.10.287.130 368 428 1.6E-21 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS18120 13140ee351a3f8760c9d772df958dd55 609 SUPERFAMILY SSF103190 88 174 1.33E-6 T 06-07-2017 IPR029151 Periplasmic sensor domain-like GTHT12_RS18120 13140ee351a3f8760c9d772df958dd55 609 Pfam PF00989 PAS fold 265 367 6.4E-10 T 06-07-2017 IPR013767 PAS fold GO:0006355 GTHT12_RS18120 13140ee351a3f8760c9d772df958dd55 609 Gene3D G3DSA:3.30.450.20 261 367 2.8E-13 T 06-07-2017 GTHT12_RS18120 13140ee351a3f8760c9d772df958dd55 609 SMART SM00387 488 600 1.3E-45 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS18120 13140ee351a3f8760c9d772df958dd55 609 SMART SM00091 263 329 1.6E-7 T 06-07-2017 IPR000014 PAS domain GTHT12_RS18120 13140ee351a3f8760c9d772df958dd55 609 SUPERFAMILY SSF55874 432 599 1.22E-48 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS18120 13140ee351a3f8760c9d772df958dd55 609 SMART SM00388 376 443 4.8E-22 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS18120 13140ee351a3f8760c9d772df958dd55 609 Pfam PF00672 HAMP domain 185 253 9.9E-17 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS18120 13140ee351a3f8760c9d772df958dd55 609 SUPERFAMILY SSF47384 363 443 6.87E-21 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS18120 13140ee351a3f8760c9d772df958dd55 609 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 489 599 6.9E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS18120 13140ee351a3f8760c9d772df958dd55 609 SUPERFAMILY SSF158472 204 253 1.83E-9 T 06-07-2017 GTHT12_RS18120 13140ee351a3f8760c9d772df958dd55 609 SMART SM00304 204 256 3.6E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS18120 13140ee351a3f8760c9d772df958dd55 609 SUPERFAMILY SSF55785 251 368 1.03E-13 T 06-07-2017 IPR000014 PAS domain GTHT12_RS18120 13140ee351a3f8760c9d772df958dd55 609 Gene3D G3DSA:3.30.450.20 72 173 7.3E-7 T 06-07-2017 GTHT12_RS18120 13140ee351a3f8760c9d772df958dd55 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 560 578 5.1E-18 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS18120 13140ee351a3f8760c9d772df958dd55 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 539 5.1E-18 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS18120 13140ee351a3f8760c9d772df958dd55 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 543 553 5.1E-18 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS18120 13140ee351a3f8760c9d772df958dd55 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 584 597 5.1E-18 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS18120 13140ee351a3f8760c9d772df958dd55 609 Pfam PF00512 His Kinase A (phospho-acceptor) domain 377 442 4.2E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS18120 13140ee351a3f8760c9d772df958dd55 609 Gene3D G3DSA:3.30.565.10 429 602 8.0E-53 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS17895 28d8b19a0b018366e5d901e8d5939119 240 Gene3D G3DSA:3.40.50.300 1 237 4.6E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17895 28d8b19a0b018366e5d901e8d5939119 240 PIRSF PIRSF039085 1 240 3.8E-120 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 GTHT12_RS17895 28d8b19a0b018366e5d901e8d5939119 240 SMART SM00382 26 221 2.8E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS17895 28d8b19a0b018366e5d901e8d5939119 240 SUPERFAMILY SSF52540 1 235 4.8E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17895 28d8b19a0b018366e5d901e8d5939119 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS17895 28d8b19a0b018366e5d901e8d5939119 240 Pfam PF00005 ABC transporter 17 165 4.0E-36 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS02330 b469ba79b41b21ac2e8d16348dcb4fdd 281 SUPERFAMILY SSF117892 89 217 1.14E-10 T 06-07-2017 IPR001107 Band 7 domain GTHT12_RS02330 b469ba79b41b21ac2e8d16348dcb4fdd 281 SMART SM00244 49 214 1.3E-7 T 06-07-2017 IPR001107 Band 7 domain GTHT12_RS02330 b469ba79b41b21ac2e8d16348dcb4fdd 281 Pfam PF01145 SPFH domain / Band 7 family 53 227 5.6E-22 T 06-07-2017 IPR001107 Band 7 domain GTHT12_RS08300 482d175edf409d61307dbb1c6a03a277 430 Pfam PF00512 His Kinase A (phospho-acceptor) domain 208 268 1.2E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS08300 482d175edf409d61307dbb1c6a03a277 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 415 5.1E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS08300 482d175edf409d61307dbb1c6a03a277 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 349 363 5.1E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS08300 482d175edf409d61307dbb1c6a03a277 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 377 5.1E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS08300 482d175edf409d61307dbb1c6a03a277 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 396 5.1E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS08300 482d175edf409d61307dbb1c6a03a277 430 Gene3D G3DSA:3.30.565.10 273 417 2.4E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS08300 482d175edf409d61307dbb1c6a03a277 430 SUPERFAMILY SSF47384 201 269 9.81E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS08300 482d175edf409d61307dbb1c6a03a277 430 SUPERFAMILY SSF55874 273 416 2.1E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS08300 482d175edf409d61307dbb1c6a03a277 430 SMART SM00388 206 272 3.6E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS08300 482d175edf409d61307dbb1c6a03a277 430 Pfam PF07694 5TMR of 5TMR-LYT 34 182 3.4E-16 T 06-07-2017 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 GTHT12_RS08300 482d175edf409d61307dbb1c6a03a277 430 Gene3D G3DSA:1.10.287.130 202 268 5.6E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS08300 482d175edf409d61307dbb1c6a03a277 430 SMART SM00387 312 418 1.0E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS08300 482d175edf409d61307dbb1c6a03a277 430 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 315 417 1.2E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS07925 a12c8c8ed9976468d1012468c29febf6 98 Pfam PF05103 DivIVA protein 8 68 4.6E-20 T 06-07-2017 IPR007793 DivIVA family GTHT12_RS07925 a12c8c8ed9976468d1012468c29febf6 98 PIRSF PIRSF029938 1 98 5.8E-39 T 06-07-2017 IPR011229 Cell cycle protein GpsB GTHT12_RS07925 a12c8c8ed9976468d1012468c29febf6 98 Hamap MF_02011 Cell cycle protein GpsB [gpsB]. 3 94 24.652 T 06-07-2017 IPR011229 Cell cycle protein GpsB GTHT12_RS07925 a12c8c8ed9976468d1012468c29febf6 98 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 8 41 2.0E-17 T 06-07-2017 IPR019933 DivIVA domain GTHT12_RS07925 a12c8c8ed9976468d1012468c29febf6 98 Gene3D G3DSA:1.20.5.170 43 68 7.5E-5 T 06-07-2017 GTHT12_RS07925 a12c8c8ed9976468d1012468c29febf6 98 SUPERFAMILY SSF75704 36 69 6.41E-5 T 06-07-2017 GTHT12_RS00275 b99a368c99b56fb850492a05ec219677 210 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 99 182 2.3E-26 T 06-07-2017 IPR020057 Ribosomal protein L25, beta domain GTHT12_RS00275 b99a368c99b56fb850492a05ec219677 210 SUPERFAMILY SSF50715 10 182 4.01E-53 T 06-07-2017 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 GTHT12_RS00275 b99a368c99b56fb850492a05ec219677 210 Gene3D G3DSA:2.170.120.20 98 186 2.5E-28 T 06-07-2017 IPR020057 Ribosomal protein L25, beta domain GTHT12_RS00275 b99a368c99b56fb850492a05ec219677 210 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 5 94 3.0E-35 T 06-07-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 GTHT12_RS00275 b99a368c99b56fb850492a05ec219677 210 Gene3D G3DSA:2.40.240.10 2 94 6.7E-27 T 06-07-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 GTHT12_RS00275 b99a368c99b56fb850492a05ec219677 210 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 5 179 1.7E-50 T 06-07-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 GTHT12_RS00275 b99a368c99b56fb850492a05ec219677 210 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 3 180 26.62 T 06-07-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 GTHT12_RS00275 b99a368c99b56fb850492a05ec219677 210 Pfam PF01386 Ribosomal L25p family 6 91 5.4E-23 T 06-07-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 GTHT12_RS12185 a7e52eae80800b5945a45f5496612165 146 Gene3D G3DSA:3.30.565.10 33 141 5.8E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS12185 a7e52eae80800b5945a45f5496612165 146 SUPERFAMILY SSF55874 29 134 5.76E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS12185 a7e52eae80800b5945a45f5496612165 146 Pfam PF13581 Histidine kinase-like ATPase domain 9 136 1.1E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS12185 a7e52eae80800b5945a45f5496612165 146 TIGRFAM TIGR01925 spIIAB: anti-sigma F factor 1 137 3.0E-71 T 06-07-2017 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0030435|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 GTHT12_RS12185 a7e52eae80800b5945a45f5496612165 146 SMART SM00387 35 140 4.3E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS12185 a7e52eae80800b5945a45f5496612165 146 Hamap MF_00637 Anti-sigma F factor [spoIIAB]. 1 140 39.565 T 06-07-2017 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0030435|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 GTHT12_RS14160 cdeefbbf23a267f9f3738d9936055054 291 TIGRFAM TIGR02834 spo_ytxC: putative sporulation protein YtxC 2 270 1.8E-83 T 06-07-2017 IPR014199 Sporulation protein YtxC GTHT12_RS14160 cdeefbbf23a267f9f3738d9936055054 291 Pfam PF08812 YtxC-like family 55 269 1.2E-54 T 06-07-2017 IPR014199 Sporulation protein YtxC GTHT12_RS14160 cdeefbbf23a267f9f3738d9936055054 291 PIRSF PIRSF012563 1 288 1.0E-119 T 06-07-2017 IPR014199 Sporulation protein YtxC GTHT12_RS15340 b73e7164031f330706df214fa0a16998 93 PIRSF PIRSF028784 1 91 2.5E-30 T 06-07-2017 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 GTHT12_RS15340 b73e7164031f330706df214fa0a16998 93 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 30 81 9.5E-17 T 06-07-2017 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 GTHT12_RS09905 b5c88565a3672a610e598f0a3227f0ed 349 Pfam PF01263 Aldose 1-epimerase 18 343 2.3E-90 T 06-07-2017 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 GTHT12_RS09905 b5c88565a3672a610e598f0a3227f0ed 349 PIRSF PIRSF005096 1 348 2.9E-138 T 06-07-2017 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 GTHT12_RS09905 b5c88565a3672a610e598f0a3227f0ed 349 Gene3D G3DSA:2.70.98.10 7 347 2.3E-126 T 06-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 GTHT12_RS09905 b5c88565a3672a610e598f0a3227f0ed 349 SUPERFAMILY SSF74650 4 345 4.83E-113 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 GTHT12_RS09905 b5c88565a3672a610e598f0a3227f0ed 349 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 175 184 - T 06-07-2017 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 GTHT12_RS15480 8533013981bb342f01715e566b322724 165 Pfam PF04608 Phosphatidylglycerophosphatase A 21 158 4.9E-21 T 06-07-2017 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 GTHT12_RS15480 8533013981bb342f01715e566b322724 165 SUPERFAMILY SSF101307 8 161 6.8E-58 T 06-07-2017 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 GTHT12_RS15480 8533013981bb342f01715e566b322724 165 PIRSF PIRSF019587 4 165 1.0E-80 T 06-07-2017 IPR026038 Putative phosphatidylglycerophosphatase GTHT12_RS15480 8533013981bb342f01715e566b322724 165 Gene3D G3DSA:1.10.3760.10 5 163 3.0E-80 T 06-07-2017 IPR027416 YutG-like domain GTHT12_RS06785 9161efca6633a60259fcdf14ac574fcf 449 ProSitePatterns PS00216 Sugar transport proteins signature 1. 60 76 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 GTHT12_RS06785 9161efca6633a60259fcdf14ac574fcf 449 SUPERFAMILY SSF103473 233 439 5.62E-74 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS06785 9161efca6633a60259fcdf14ac574fcf 449 SUPERFAMILY SSF103473 8 194 5.62E-74 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS06785 9161efca6633a60259fcdf14ac574fcf 449 Pfam PF07690 Major Facilitator Superfamily 12 294 9.0E-46 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS06785 9161efca6633a60259fcdf14ac574fcf 449 Gene3D G3DSA:1.20.1250.20 9 185 2.4E-35 T 06-07-2017 GTHT12_RS06785 9161efca6633a60259fcdf14ac574fcf 449 Gene3D G3DSA:1.20.1250.20 248 443 4.3E-27 T 06-07-2017 GTHT12_RS05345 0f3b35e498766591e4323b029588edd5 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 89 102 5.7E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 GTHT12_RS05345 0f3b35e498766591e4323b029588edd5 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 5.7E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 GTHT12_RS05345 0f3b35e498766591e4323b029588edd5 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 5.7E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 GTHT12_RS05345 0f3b35e498766591e4323b029588edd5 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 199 213 5.7E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 GTHT12_RS05345 0f3b35e498766591e4323b029588edd5 273 SUPERFAMILY SSF53474 1 249 7.56E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS05345 0f3b35e498766591e4323b029588edd5 273 Gene3D G3DSA:3.40.50.1820 2 249 7.6E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS05345 0f3b35e498766591e4323b029588edd5 273 Pfam PF00561 alpha/beta hydrolase fold 21 120 3.1E-15 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 GTHT12_RS03030 2237555c75674fce27a57bbfe0b341ec 158 Pfam PF14184 Regulatory protein YrvL 11 130 1.2E-18 T 06-07-2017 IPR025912 Regulatory protein YrvL GTHT12_RS17525 ed3ed3f13361695ca7468eb153afb325 412 Gene3D G3DSA:3.90.1150.10 280 411 5.1E-57 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS17525 ed3ed3f13361695ca7468eb153afb325 412 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 411 55.071 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 GTHT12_RS17525 ed3ed3f13361695ca7468eb153afb325 412 PIRSF PIRSF000412 1 411 2.0E-179 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 GTHT12_RS17525 ed3ed3f13361695ca7468eb153afb325 412 SUPERFAMILY SSF53383 2 410 5.85E-188 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS17525 ed3ed3f13361695ca7468eb153afb325 412 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 06-07-2017 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 GTHT12_RS17525 ed3ed3f13361695ca7468eb153afb325 412 Pfam PF00464 Serine hydroxymethyltransferase 5 380 1.1E-186 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 GTHT12_RS17525 ed3ed3f13361695ca7468eb153afb325 412 Gene3D G3DSA:3.40.640.10 33 279 1.2E-114 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS00860 6a94b6104533d8027d0a58f0cbbdcbc1 251 Gene3D G3DSA:3.20.20.370 15 245 1.7E-61 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 GTHT12_RS00860 6a94b6104533d8027d0a58f0cbbdcbc1 251 Pfam PF01522 Polysaccharide deacetylase 51 172 8.8E-26 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 GTHT12_RS00860 6a94b6104533d8027d0a58f0cbbdcbc1 251 TIGRFAM TIGR02764 spore_ybaN_pdaB: polysaccharide deacetylase family sporulation protein PdaB 49 240 1.4E-80 T 06-07-2017 IPR014132 Sporulation polysaccharide deacetylase, PdaB GTHT12_RS00860 6a94b6104533d8027d0a58f0cbbdcbc1 251 SUPERFAMILY SSF88713 14 240 2.05E-58 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 GTHT12_RS16530 d0319a348bae9aefc7e3273dccbe8ee1 447 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 141 172 - T 06-07-2017 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 GTHT12_RS16530 d0319a348bae9aefc7e3273dccbe8ee1 447 Gene3D G3DSA:3.40.50.720 3 168 2.1E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS16530 d0319a348bae9aefc7e3273dccbe8ee1 447 Pfam PF02056 Family 4 glycosyl hydrolase 6 187 6.7E-73 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 GTHT12_RS16530 d0319a348bae9aefc7e3273dccbe8ee1 447 SUPERFAMILY SSF56327 173 439 1.06E-101 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 GTHT12_RS16530 d0319a348bae9aefc7e3273dccbe8ee1 447 SUPERFAMILY SSF51735 4 169 9.27E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS16530 d0319a348bae9aefc7e3273dccbe8ee1 447 PRINTS PR00732 Glycosyl hydrolase family 4 signature 112 132 2.2E-52 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 GTHT12_RS16530 d0319a348bae9aefc7e3273dccbe8ee1 447 PRINTS PR00732 Glycosyl hydrolase family 4 signature 77 93 2.2E-52 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 GTHT12_RS16530 d0319a348bae9aefc7e3273dccbe8ee1 447 PRINTS PR00732 Glycosyl hydrolase family 4 signature 167 178 2.2E-52 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 GTHT12_RS16530 d0319a348bae9aefc7e3273dccbe8ee1 447 PRINTS PR00732 Glycosyl hydrolase family 4 signature 6 21 2.2E-52 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 GTHT12_RS16530 d0319a348bae9aefc7e3273dccbe8ee1 447 PRINTS PR00732 Glycosyl hydrolase family 4 signature 193 205 2.2E-52 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 GTHT12_RS16530 d0319a348bae9aefc7e3273dccbe8ee1 447 PRINTS PR00732 Glycosyl hydrolase family 4 signature 98 111 2.2E-52 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 GTHT12_RS16530 d0319a348bae9aefc7e3273dccbe8ee1 447 PRINTS PR00732 Glycosyl hydrolase family 4 signature 141 158 2.2E-52 T 06-07-2017 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 GTHT12_RS16530 d0319a348bae9aefc7e3273dccbe8ee1 447 Gene3D G3DSA:3.90.110.10 170 437 1.4E-103 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 GTHT12_RS16530 d0319a348bae9aefc7e3273dccbe8ee1 447 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 197 413 3.4E-51 T 06-07-2017 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 GTHT12_RS10745 f48b061052c1c98ae8489c0a95a7327b 403 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 398 1.2E-150 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 GTHT12_RS10745 f48b061052c1c98ae8489c0a95a7327b 403 ProSitePatterns PS00737 Thiolases signature 2. 346 362 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 GTHT12_RS10745 f48b061052c1c98ae8489c0a95a7327b 403 Pfam PF02803 Thiolase, C-terminal domain 277 398 9.5E-51 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 GTHT12_RS10745 f48b061052c1c98ae8489c0a95a7327b 403 Gene3D G3DSA:3.40.47.10 4 126 2.4E-75 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS10745 f48b061052c1c98ae8489c0a95a7327b 403 Gene3D G3DSA:3.40.47.10 202 282 2.4E-75 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS10745 f48b061052c1c98ae8489c0a95a7327b 403 SUPERFAMILY SSF53901 4 277 2.8E-87 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS10745 f48b061052c1c98ae8489c0a95a7327b 403 Gene3D G3DSA:3.40.47.10 284 399 2.4E-67 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS10745 f48b061052c1c98ae8489c0a95a7327b 403 Gene3D G3DSA:3.40.47.10 152 201 2.4E-67 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS10745 f48b061052c1c98ae8489c0a95a7327b 403 TIGRFAM TIGR02430 pcaF: 3-oxoadipyl-CoA thiolase 3 398 2.5E-181 T 06-07-2017 IPR012793 Beta-ketoadipyl CoA thiolase GO:0016747|GO:0019619 KEGG: 00250+2.3.1.17|KEGG: 00360+2.3.1.174|KEGG: 00362+2.3.1.174|MetaCyc: PWY-1361|MetaCyc: PWY-2361|MetaCyc: PWY-6185 GTHT12_RS10745 f48b061052c1c98ae8489c0a95a7327b 403 ProSitePatterns PS00099 Thiolases active site. 381 394 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 GTHT12_RS10745 f48b061052c1c98ae8489c0a95a7327b 403 Pfam PF00108 Thiolase, N-terminal domain 5 269 7.3E-84 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 GTHT12_RS10745 f48b061052c1c98ae8489c0a95a7327b 403 PIRSF PIRSF000429 1 401 1.1E-141 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 GTHT12_RS10745 f48b061052c1c98ae8489c0a95a7327b 403 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 GTHT12_RS10745 f48b061052c1c98ae8489c0a95a7327b 403 SUPERFAMILY SSF53901 278 398 3.61E-45 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS08865 4463439bdd796a977c9324a0314ddd00 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 3.4E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS08865 4463439bdd796a977c9324a0314ddd00 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 3.4E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS08865 4463439bdd796a977c9324a0314ddd00 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 3.4E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS08865 4463439bdd796a977c9324a0314ddd00 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 3.4E-5 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS08865 4463439bdd796a977c9324a0314ddd00 149 Gene3D G3DSA:1.10.10.10 25 140 4.1E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS08865 4463439bdd796a977c9324a0314ddd00 149 SMART SM00347 28 129 1.3E-14 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS08865 4463439bdd796a977c9324a0314ddd00 149 SUPERFAMILY SSF46785 27 142 1.3E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS08865 4463439bdd796a977c9324a0314ddd00 149 Pfam PF12802 MarR family 36 93 7.4E-12 T 06-07-2017 GTHT12_RS11985 828b84e28baca987c17faf236226c2cb 204 Gene3D G3DSA:1.10.287.210 116 204 7.0E-35 T 06-07-2017 GTHT12_RS11985 828b84e28baca987c17faf236226c2cb 204 SUPERFAMILY SSF50729 14 203 5.53E-69 T 06-07-2017 IPR011993 PH domain-like GTHT12_RS11985 828b84e28baca987c17faf236226c2cb 204 Pfam PF11724 YvbH-like oligomerisation region 144 203 2.1E-22 T 06-07-2017 IPR021722 Uncharacterised domain YvbH-like, oligomerisation domain GTHT12_RS11985 828b84e28baca987c17faf236226c2cb 204 Pfam PF08000 Bacterial PH domain 10 131 3.3E-37 T 06-07-2017 IPR012544 Bacterial Pleckstrin homology domain GTHT12_RS11985 828b84e28baca987c17faf236226c2cb 204 Gene3D G3DSA:2.30.29.50 13 115 2.6E-37 T 06-07-2017 IPR012544 Bacterial Pleckstrin homology domain GTHT12_RS09405 1963b0b15e2c65b0695fa8703428c605 352 Gene3D G3DSA:1.10.1610.10 4 68 1.7E-32 T 06-07-2017 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 GTHT12_RS09405 1963b0b15e2c65b0695fa8703428c605 352 SUPERFAMILY SSF52733 5 342 7.19E-122 T 06-07-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 GTHT12_RS09405 1963b0b15e2c65b0695fa8703428c605 352 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 8 343 37.062 T 06-07-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 GTHT12_RS09405 1963b0b15e2c65b0695fa8703428c605 352 Gene3D G3DSA:3.40.50.10210 69 323 6.2E-116 T 06-07-2017 GTHT12_RS09405 1963b0b15e2c65b0695fa8703428c605 352 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 12 341 9.1E-141 T 06-07-2017 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 GTHT12_RS09405 1963b0b15e2c65b0695fa8703428c605 352 Pfam PF02277 Phosphoribosyltransferase 6 341 4.0E-138 T 06-07-2017 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 GTHT12_RS13165 8f09173eb311cb5b18404b733fc77b80 89 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 89 2.0E-34 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS13165 8f09173eb311cb5b18404b733fc77b80 89 Gene3D G3DSA:1.20.58.110 2 86 2.0E-31 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS13165 8f09173eb311cb5b18404b733fc77b80 89 SUPERFAMILY SSF46992 3 86 1.96E-31 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS13165 8f09173eb311cb5b18404b733fc77b80 89 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 86 6.5E-31 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS13165 8f09173eb311cb5b18404b733fc77b80 89 Pfam PF01649 Ribosomal protein S20 2 84 6.2E-30 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS13165 8f09173eb311cb5b18404b733fc77b80 89 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 18.265 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS09490 6dd48d166adbf2fae8f85ab4c737b628 161 SUPERFAMILY SSF89562 2 156 3.4E-48 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein GTHT12_RS09490 6dd48d166adbf2fae8f85ab4c737b628 161 Gene3D G3DSA:3.50.30.40 2 156 5.7E-50 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein GTHT12_RS09490 6dd48d166adbf2fae8f85ab4c737b628 161 TIGRFAM TIGR01935 NOT-MenG: RraA family 3 151 3.4E-56 T 06-07-2017 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 GTHT12_RS09490 6dd48d166adbf2fae8f85ab4c737b628 161 Pfam PF03737 Demethylmenaquinone methyltransferase 3 151 1.0E-43 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein GTHT12_RS10620 af874dc0b0842966142e41f227dae932 225 Pfam PF05138 Phenylacetic acid catabolic protein 17 219 7.1E-19 T 06-07-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 GTHT12_RS10620 af874dc0b0842966142e41f227dae932 225 SUPERFAMILY SSF47240 22 223 9.53E-32 T 06-07-2017 IPR009078 Ferritin-like superfamily GTHT12_RS10620 af874dc0b0842966142e41f227dae932 225 Gene3D G3DSA:1.20.1260.10 20 219 1.3E-29 T 06-07-2017 IPR012347 Ferritin-related GTHT12_RS03390 40c36c42c8a277cf66c6cefc537c4b56 585 SUPERFAMILY SSF55957 446 481 2.09E-15 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS03390 40c36c42c8a277cf66c6cefc537c4b56 585 SUPERFAMILY SSF55957 513 573 2.09E-15 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS03390 40c36c42c8a277cf66c6cefc537c4b56 585 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 296 311 7.2E-8 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS03390 40c36c42c8a277cf66c6cefc537c4b56 585 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 229 248 7.2E-8 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS03390 40c36c42c8a277cf66c6cefc537c4b56 585 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 139 153 7.2E-8 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS03390 40c36c42c8a277cf66c6cefc537c4b56 585 Gene3D G3DSA:3.30.310.50 480 572 4.2E-25 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS03390 40c36c42c8a277cf66c6cefc537c4b56 585 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 491 553 8.8E-10 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS03390 40c36c42c8a277cf66c6cefc537c4b56 585 SUPERFAMILY SSF53738 304 455 3.26E-32 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS03390 40c36c42c8a277cf66c6cefc537c4b56 585 Gene3D G3DSA:3.40.120.10 231 315 7.6E-24 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS03390 40c36c42c8a277cf66c6cefc537c4b56 585 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 06-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS03390 40c36c42c8a277cf66c6cefc537c4b56 585 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 43 181 7.9E-43 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS03390 40c36c42c8a277cf66c6cefc537c4b56 585 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 210 315 8.0E-25 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS03390 40c36c42c8a277cf66c6cefc537c4b56 585 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 325 451 1.4E-22 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS03390 40c36c42c8a277cf66c6cefc537c4b56 585 SUPERFAMILY SSF53738 30 236 1.29E-49 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS03390 40c36c42c8a277cf66c6cefc537c4b56 585 Gene3D G3DSA:3.40.120.10 15 217 5.7E-63 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS03390 40c36c42c8a277cf66c6cefc537c4b56 585 SUPERFAMILY SSF53738 211 312 7.65E-16 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS03390 40c36c42c8a277cf66c6cefc537c4b56 585 Gene3D G3DSA:3.40.120.10 322 453 3.6E-34 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS16550 f0acfe48ead69f37c3cf1d93824a7718 455 Gene3D G3DSA:1.10.45.10 414 452 8.0E-11 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 GTHT12_RS16550 f0acfe48ead69f37c3cf1d93824a7718 455 Pfam PF01565 FAD binding domain 39 175 7.0E-43 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 GTHT12_RS16550 f0acfe48ead69f37c3cf1d93824a7718 455 SUPERFAMILY SSF56176 6 213 9.35E-70 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 GTHT12_RS16550 f0acfe48ead69f37c3cf1d93824a7718 455 Pfam PF02913 FAD linked oxidases, C-terminal domain 212 452 1.3E-62 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 GTHT12_RS16550 f0acfe48ead69f37c3cf1d93824a7718 455 Gene3D G3DSA:3.30.43.10 5 93 4.5E-28 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 GTHT12_RS16550 f0acfe48ead69f37c3cf1d93824a7718 455 Gene3D G3DSA:3.30.465.10 94 213 5.8E-45 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 GTHT12_RS16550 f0acfe48ead69f37c3cf1d93824a7718 455 SUPERFAMILY SSF55103 218 454 4.09E-66 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 GTHT12_RS07450 aedf326a95cb9e7d14475b7bbc70181b 183 SUPERFAMILY SSF52317 1 182 2.01E-49 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS07450 aedf326a95cb9e7d14475b7bbc70181b 183 Pfam PF01965 DJ-1/PfpI family 3 180 5.2E-42 T 06-07-2017 IPR002818 DJ-1/PfpI GTHT12_RS07450 aedf326a95cb9e7d14475b7bbc70181b 183 Gene3D G3DSA:3.40.50.880 1 182 8.2E-50 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS07450 aedf326a95cb9e7d14475b7bbc70181b 183 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 5 183 1.3E-48 T 06-07-2017 IPR006286 Peptidase C56, PfpI GTHT12_RS14955 389c3eb7e6bdc3d4fda7c0306ff7cae6 215 Gene3D G3DSA:2.40.50.40 109 176 3.8E-21 T 06-07-2017 GTHT12_RS14955 389c3eb7e6bdc3d4fda7c0306ff7cae6 215 SMART SM00850 117 214 9.7E-31 T 06-07-2017 IPR007492 LytTR DNA-binding domain GO:0003677 GTHT12_RS14955 389c3eb7e6bdc3d4fda7c0306ff7cae6 215 Pfam PF04397 LytTr DNA-binding domain 117 213 7.3E-26 T 06-07-2017 IPR007492 LytTR DNA-binding domain GO:0003677 GTHT12_RS14955 389c3eb7e6bdc3d4fda7c0306ff7cae6 215 Gene3D G3DSA:2.20.25.10 178 215 1.2E-20 T 06-07-2017 GTHT12_RS08570 c1019fccdcb45c6d9f97208537c92567 254 Gene3D G3DSA:3.40.50.300 3 247 4.9E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08570 c1019fccdcb45c6d9f97208537c92567 254 SUPERFAMILY SSF52540 3 249 1.11E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08570 c1019fccdcb45c6d9f97208537c92567 254 Pfam PF00005 ABC transporter 19 178 2.1E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS08570 c1019fccdcb45c6d9f97208537c92567 254 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 227 249 9.2E-13 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal GTHT12_RS08570 c1019fccdcb45c6d9f97208537c92567 254 SMART SM00382 27 227 2.7E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS04100 eeca5663652bc5918a0c0e3d015dc55d 391 Gene3D G3DSA:1.20.1250.20 10 192 1.7E-28 T 06-07-2017 GTHT12_RS04100 eeca5663652bc5918a0c0e3d015dc55d 391 Gene3D G3DSA:1.20.1250.20 201 377 1.7E-26 T 06-07-2017 GTHT12_RS04100 eeca5663652bc5918a0c0e3d015dc55d 391 SUPERFAMILY SSF103473 4 383 6.15E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS04100 eeca5663652bc5918a0c0e3d015dc55d 391 Pfam PF07690 Major Facilitator Superfamily 13 240 8.8E-29 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS10060 398cfab11fd70836adadf1868b31be72 639 Gene3D G3DSA:3.40.50.970 3 211 3.0E-55 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS10060 398cfab11fd70836adadf1868b31be72 639 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 196 6.6E-35 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 GTHT12_RS10060 398cfab11fd70836adadf1868b31be72 639 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 471 490 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 GTHT12_RS10060 398cfab11fd70836adadf1868b31be72 639 SUPERFAMILY SSF52467 186 358 2.65E-41 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS10060 398cfab11fd70836adadf1868b31be72 639 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 435 594 3.0E-37 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 GTHT12_RS10060 398cfab11fd70836adadf1868b31be72 639 Gene3D G3DSA:3.40.50.1220 212 357 1.7E-41 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS10060 398cfab11fd70836adadf1868b31be72 639 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 220 350 4.1E-34 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 GTHT12_RS10060 398cfab11fd70836adadf1868b31be72 639 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 5 637 2.3E-294 T 06-07-2017 IPR030817 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 GTHT12_RS10060 398cfab11fd70836adadf1868b31be72 639 Gene3D G3DSA:3.40.50.970 403 633 1.7E-57 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS10060 398cfab11fd70836adadf1868b31be72 639 Hamap MF_01669 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase [iolD]. 1 639 57.481 T 06-07-2017 IPR023757 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase, Firmicutes GO:0000287|GO:0016787|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 GTHT12_RS10060 398cfab11fd70836adadf1868b31be72 639 SUPERFAMILY SSF52518 3 209 2.99E-33 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS10060 398cfab11fd70836adadf1868b31be72 639 SUPERFAMILY SSF52518 412 627 4.37E-52 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS09910 677d5a4f202d3ca61bc4e036b973a702 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 277 4.2E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS09910 677d5a4f202d3ca61bc4e036b973a702 288 SUPERFAMILY SSF161098 16 288 1.03E-69 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS09910 677d5a4f202d3ca61bc4e036b973a702 288 Gene3D G3DSA:1.10.3720.10 15 273 2.7E-64 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS00790 68d576a84b73cd3d285d95509e266088 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 129 34.765 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00790 68d576a84b73cd3d285d95509e266088 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 11 126 1.8E-59 T 06-07-2017 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00790 68d576a84b73cd3d285d95509e266088 129 Gene3D G3DSA:3.30.420.80 5 129 2.0E-56 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00790 68d576a84b73cd3d285d95509e266088 129 PIRSF PIRSF002131 1 129 1.6E-54 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00790 68d576a84b73cd3d285d95509e266088 129 Pfam PF00411 Ribosomal protein S11 19 128 7.1E-54 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00790 68d576a84b73cd3d285d95509e266088 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 06-07-2017 IPR018102 Ribosomal S11, conserved site GTHT12_RS00790 68d576a84b73cd3d285d95509e266088 129 SUPERFAMILY SSF53137 14 129 2.29E-51 T 06-07-2017 GTHT12_RS13950 3fa4c0c22e3c6961133f7bd5705a9850 202 Gene3D G3DSA:1.20.950.10 5 201 7.6E-52 T 06-07-2017 GTHT12_RS13950 3fa4c0c22e3c6961133f7bd5705a9850 202 SUPERFAMILY SSF81343 4 201 2.22E-61 T 06-07-2017 GTHT12_RS13950 3fa4c0c22e3c6961133f7bd5705a9850 202 PIRSF PIRSF000170 1 202 2.0E-99 T 06-07-2017 IPR016002 Succinate dehydrogenase cytochrome b558 subunit, Firmicute GTHT12_RS13950 3fa4c0c22e3c6961133f7bd5705a9850 202 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 5 201 4.9E-53 T 06-07-2017 IPR011138 Succinate dehydrogenase cytochrome b558 subunit GTHT12_RS13950 3fa4c0c22e3c6961133f7bd5705a9850 202 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 92 193 1.1E-12 T 06-07-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GTHT12_RS04415 9982a4d254a86f44ac28d5a3a11d21c1 392 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 340 364 - T 06-07-2017 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 GTHT12_RS04415 9982a4d254a86f44ac28d5a3a11d21c1 392 Pfam PF01098 Cell cycle protein 15 383 3.5E-95 T 06-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 GTHT12_RS07425 1fe1c003fdd6453e92b786bdb8669dd8 203 SUPERFAMILY SSF48317 6 196 3.53E-32 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase GTHT12_RS07425 1fe1c003fdd6453e92b786bdb8669dd8 203 SMART SM00014 75 187 1.1E-20 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase GTHT12_RS07425 1fe1c003fdd6453e92b786bdb8669dd8 203 Pfam PF01569 PAP2 superfamily 79 193 2.1E-21 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase GTHT12_RS07425 1fe1c003fdd6453e92b786bdb8669dd8 203 Gene3D G3DSA:1.20.144.10 52 199 6.9E-26 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase GTHT12_RS06095 3281ea56c1ad28bc8fe71a5830e06223 319 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 06-07-2017 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GTHT12_RS06095 3281ea56c1ad28bc8fe71a5830e06223 319 Gene3D G3DSA:3.40.50.170 3 205 3.3E-74 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GTHT12_RS06095 3281ea56c1ad28bc8fe71a5830e06223 319 Pfam PF02911 Formyl transferase, C-terminal domain 205 302 2.6E-28 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GTHT12_RS06095 3281ea56c1ad28bc8fe71a5830e06223 319 Gene3D G3DSA:3.10.25.10 208 313 2.7E-34 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GTHT12_RS06095 3281ea56c1ad28bc8fe71a5830e06223 319 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 3 304 1.3E-114 T 06-07-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 GTHT12_RS06095 3281ea56c1ad28bc8fe71a5830e06223 319 Pfam PF00551 Formyl transferase 3 180 2.6E-44 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GTHT12_RS06095 3281ea56c1ad28bc8fe71a5830e06223 319 SUPERFAMILY SSF50486 205 306 1.04E-31 T 06-07-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 GTHT12_RS06095 3281ea56c1ad28bc8fe71a5830e06223 319 SUPERFAMILY SSF53328 4 206 2.75E-71 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GTHT12_RS06095 3281ea56c1ad28bc8fe71a5830e06223 319 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 2 305 36.573 T 06-07-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 GTHT12_RS10500 1555cbcf5ae488c3658652d751f58050 733 Pfam PF00920 Dehydratase family 554 674 5.4E-22 T 06-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 GTHT12_RS10500 1555cbcf5ae488c3658652d751f58050 733 Pfam PF00920 Dehydratase family 78 514 1.9E-44 T 06-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 GTHT12_RS10500 1555cbcf5ae488c3658652d751f58050 733 SUPERFAMILY SSF52016 550 655 3.92E-22 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel GTHT12_RS10500 1555cbcf5ae488c3658652d751f58050 733 SUPERFAMILY SSF143975 38 460 6.67E-48 T 06-07-2017 GTHT12_RS11975 6ae63f062f0077120cf525a683791989 344 SUPERFAMILY SSF81345 5 337 2.48E-76 T 06-07-2017 IPR029022 ABC transporter, BtuC-like GTHT12_RS11975 6ae63f062f0077120cf525a683791989 344 Gene3D G3DSA:1.10.3470.10 5 341 7.5E-101 T 06-07-2017 IPR029022 ABC transporter, BtuC-like GTHT12_RS11975 6ae63f062f0077120cf525a683791989 344 Pfam PF01032 FecCD transport family 17 337 1.3E-87 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 GTHT12_RS13030 8907ab9ac5d53c5f6ddccb00a003db7e 258 Gene3D G3DSA:2.40.50.140 4 81 3.6E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS13030 8907ab9ac5d53c5f6ddccb00a003db7e 258 Hamap MF_00201 DNA repair protein RecO [recO]. 1 243 31.119 T 06-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 GTHT12_RS13030 8907ab9ac5d53c5f6ddccb00a003db7e 258 SUPERFAMILY SSF57863 81 232 9.68E-48 T 06-07-2017 GTHT12_RS13030 8907ab9ac5d53c5f6ddccb00a003db7e 258 Pfam PF02565 Recombination protein O C terminal 82 237 1.7E-45 T 06-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 GTHT12_RS13030 8907ab9ac5d53c5f6ddccb00a003db7e 258 TIGRFAM TIGR00613 reco: DNA repair protein RecO 4 243 2.0E-74 T 06-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 GTHT12_RS13030 8907ab9ac5d53c5f6ddccb00a003db7e 258 Pfam PF11967 Recombination protein O N terminal 1 77 1.0E-25 T 06-07-2017 IPR022572 DNA replication/recombination mediator RecO, N-terminal GTHT12_RS13030 8907ab9ac5d53c5f6ddccb00a003db7e 258 SUPERFAMILY SSF50249 1 77 4.97E-19 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS03505 3f5a4f0bfd1fc2862707e992acc55d45 379 SUPERFAMILY SSF54373 226 313 8.11E-19 T 06-07-2017 GTHT12_RS03505 3f5a4f0bfd1fc2862707e992acc55d45 379 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 8 358 1.3E-100 T 06-07-2017 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 GTHT12_RS03505 3f5a4f0bfd1fc2862707e992acc55d45 379 Pfam PF01266 FAD dependent oxidoreductase 7 353 2.5E-75 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 GTHT12_RS03505 3f5a4f0bfd1fc2862707e992acc55d45 379 Gene3D G3DSA:3.30.9.10 216 311 1.2E-17 T 06-07-2017 GTHT12_RS03505 3f5a4f0bfd1fc2862707e992acc55d45 379 Gene3D G3DSA:3.30.9.10 114 130 1.2E-17 T 06-07-2017 GTHT12_RS03505 3f5a4f0bfd1fc2862707e992acc55d45 379 SUPERFAMILY SSF51905 6 226 1.13E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS03505 3f5a4f0bfd1fc2862707e992acc55d45 379 SUPERFAMILY SSF51905 314 371 1.13E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS03505 3f5a4f0bfd1fc2862707e992acc55d45 379 Gene3D G3DSA:3.50.50.60 314 372 7.1E-66 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS03505 3f5a4f0bfd1fc2862707e992acc55d45 379 Gene3D G3DSA:3.50.50.60 6 85 7.1E-66 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS03505 3f5a4f0bfd1fc2862707e992acc55d45 379 Gene3D G3DSA:3.50.50.60 145 215 7.1E-66 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS15960 57689fa8f384b0a1e03f655a8e3f19cf 490 Pfam PF13432 Tetratricopeptide repeat 26 73 8.8E-4 T 06-07-2017 GTHT12_RS15960 57689fa8f384b0a1e03f655a8e3f19cf 490 Pfam PF13432 Tetratricopeptide repeat 156 217 1.7E-8 T 06-07-2017 GTHT12_RS15960 57689fa8f384b0a1e03f655a8e3f19cf 490 SUPERFAMILY SSF48452 19 121 1.33E-19 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS15960 57689fa8f384b0a1e03f655a8e3f19cf 490 SUPERFAMILY SSF48452 148 230 1.33E-19 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS15960 57689fa8f384b0a1e03f655a8e3f19cf 490 SMART SM00028 90 123 150.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS15960 57689fa8f384b0a1e03f655a8e3f19cf 490 SMART SM00028 21 54 0.59 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS15960 57689fa8f384b0a1e03f655a8e3f19cf 490 SMART SM00028 184 217 5.9E-4 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS15960 57689fa8f384b0a1e03f655a8e3f19cf 490 SMART SM00028 150 183 44.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS15960 57689fa8f384b0a1e03f655a8e3f19cf 490 SUPERFAMILY SSF48452 187 319 8.16E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS15960 57689fa8f384b0a1e03f655a8e3f19cf 490 Gene3D G3DSA:1.25.40.10 19 319 4.0E-36 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS15960 57689fa8f384b0a1e03f655a8e3f19cf 490 Gene3D G3DSA:1.10.10.10 454 488 6.9E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS09850 af93b50adaa05e35fdc68a4063dcdaa3 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 81 4.9E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS09850 af93b50adaa05e35fdc68a4063dcdaa3 232 SMART SM00345 23 81 1.5E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS09850 af93b50adaa05e35fdc68a4063dcdaa3 232 SUPERFAMILY SSF48008 88 216 6.54E-22 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal GTHT12_RS09850 af93b50adaa05e35fdc68a4063dcdaa3 232 SMART SM00895 91 215 1.1E-15 T 06-07-2017 IPR011711 GntR, C-terminal GTHT12_RS09850 af93b50adaa05e35fdc68a4063dcdaa3 232 Gene3D G3DSA:1.10.10.10 7 82 5.4E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS09850 af93b50adaa05e35fdc68a4063dcdaa3 232 Pfam PF07729 FCD domain 95 214 8.9E-23 T 06-07-2017 IPR011711 GntR, C-terminal GTHT12_RS09850 af93b50adaa05e35fdc68a4063dcdaa3 232 SUPERFAMILY SSF46785 17 91 8.07E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS09850 af93b50adaa05e35fdc68a4063dcdaa3 232 Gene3D G3DSA:1.20.120.530 88 217 1.9E-22 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Pfam PF00501 AMP-binding enzyme 463 860 3.6E-110 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Pfam PF00501 AMP-binding enzyme 1522 1937 1.6E-107 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Gene3D G3DSA:1.10.1200.10 2050 2111 4.7E-27 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Gene3D G3DSA:1.10.1200.10 973 1037 7.6E-27 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Gene3D G3DSA:3.40.50.980 458 614 2.3E-54 T 06-07-2017 GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 SUPERFAMILY SSF47336 962 1034 4.06E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Pfam PF13193 AMP-binding enzyme C-terminal domain 1945 2020 1.4E-16 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Pfam PF13193 AMP-binding enzyme C-terminal domain 868 944 5.4E-12 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 SUPERFAMILY SSF52777 9 183 1.33E-36 T 06-07-2017 GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1672 1683 - T 06-07-2017 IPR020845 AMP-binding, conserved site GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1543 1961 1.0E-140 T 06-07-2017 IPR010071 Amino acid adenylation domain GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 485 884 1.5E-138 T 06-07-2017 IPR010071 Amino acid adenylation domain GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 ProSitePatterns PS00012 Phosphopantetheine attachment site. 993 1008 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 SMART SM00823 Phosphopantetheine attachment site 969 1038 2.9E-8 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 SMART SM00823 Phosphopantetheine attachment site 2045 2114 6.7E-9 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Pfam PF00975 Thioesterase domain 2133 2289 3.3E-29 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 SUPERFAMILY SSF56801 427 982 6.67E-163 T 06-07-2017 GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 SUPERFAMILY SSF52777 189 448 2.67E-40 T 06-07-2017 GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 SMART SM00824 Thioesterase 2135 2293 0.0063 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Pfam PF13745 HxxPF-repeated domain 1373 1469 1.6E-28 T 06-07-2017 GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Gene3D G3DSA:2.30.38.10 773 849 2.3E-30 T 06-07-2017 GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Gene3D G3DSA:2.30.38.10 1848 1926 5.2E-26 T 06-07-2017 GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 SUPERFAMILY SSF52777 1055 1227 8.56E-49 T 06-07-2017 GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 SUPERFAMILY SSF52777 1240 1486 2.22E-65 T 06-07-2017 GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Pfam PF00550 Phosphopantetheine attachment site 972 1034 1.6E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Pfam PF00550 Phosphopantetheine attachment site 2048 2108 2.6E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Pfam PF00668 Condensation domain 7 299 1.0E-56 T 06-07-2017 IPR001242 Condensation domain GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Pfam PF00668 Condensation domain 1050 1350 2.2E-70 T 06-07-2017 IPR001242 Condensation domain GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 SUPERFAMILY SSF56801 1480 2057 2.35E-171 T 06-07-2017 GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Gene3D G3DSA:3.40.50.980 1516 1681 9.2E-58 T 06-07-2017 GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Gene3D G3DSA:3.30.300.30 1932 2049 3.6E-46 T 06-07-2017 GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Gene3D G3DSA:3.30.300.30 856 972 1.6E-41 T 06-07-2017 GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 ProSitePatterns PS00455 Putative AMP-binding domain signature. 608 619 - T 06-07-2017 IPR020845 AMP-binding, conserved site GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 SUPERFAMILY SSF47336 2039 2110 6.81E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Gene3D G3DSA:3.40.50.980 615 772 7.8E-42 T 06-07-2017 GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Gene3D G3DSA:3.40.50.980 1682 1837 1.9E-51 T 06-07-2017 GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Gene3D G3DSA:3.40.50.1820 2117 2236 2.7E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 Gene3D G3DSA:3.40.50.1820 2309 2377 2.7E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS01040 c6d8e2d6ed0a658fcc581bb92edd7848 2384 SUPERFAMILY SSF53474 2113 2376 2.58E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS00780 30e5d16ac4c20c5683abdc55a8a6cdc7 37 Pfam PF00444 Ribosomal protein L36 1 37 5.5E-20 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00780 30e5d16ac4c20c5683abdc55a8a6cdc7 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.765 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00780 30e5d16ac4c20c5683abdc55a8a6cdc7 37 SUPERFAMILY SSF57840 1 37 2.22E-17 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00780 30e5d16ac4c20c5683abdc55a8a6cdc7 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 1.0E-8 T 06-07-2017 GTHT12_RS00780 30e5d16ac4c20c5683abdc55a8a6cdc7 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00780 30e5d16ac4c20c5683abdc55a8a6cdc7 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 2.7E-24 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS17585 0f876cd697423da4f88a01918b7ad9f3 66 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 66 27.784 T 06-07-2017 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS17585 0f876cd697423da4f88a01918b7ad9f3 66 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 65 1.4E-30 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS17585 0f876cd697423da4f88a01918b7ad9f3 66 ProSitePatterns PS01143 Ribosomal protein L31 signature. 34 55 - T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS17585 0f876cd697423da4f88a01918b7ad9f3 66 Pfam PF01197 Ribosomal protein L31 1 64 2.3E-32 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS17585 0f876cd697423da4f88a01918b7ad9f3 66 PRINTS PR01249 Ribosomal protein L31 signature 30 45 8.7E-23 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS17585 0f876cd697423da4f88a01918b7ad9f3 66 PRINTS PR01249 Ribosomal protein L31 signature 2 19 8.7E-23 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS17585 0f876cd697423da4f88a01918b7ad9f3 66 PRINTS PR01249 Ribosomal protein L31 signature 45 63 8.7E-23 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS17585 0f876cd697423da4f88a01918b7ad9f3 66 SUPERFAMILY SSF143800 1 65 5.1E-26 T 06-07-2017 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 335 355 - T 06-07-2017 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 SUPERFAMILY SSF52833 1 100 1.9E-28 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 SUPERFAMILY SSF52833 102 193 1.1E-23 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 Pfam PF13192 Thioredoxin domain 123 193 1.5E-9 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 Gene3D G3DSA:3.50.50.60 330 439 2.5E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 Gene3D G3DSA:3.40.30.10 101 193 3.0E-36 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 261 271 9.2E-68 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 433 454 9.2E-68 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 467 485 9.2E-68 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 209 231 9.2E-68 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 395 411 9.2E-68 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 306 314 9.2E-68 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 343 367 9.2E-68 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 241 256 9.2E-68 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 328 340 9.2E-68 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 Gene3D G3DSA:3.40.30.10 1 92 5.3E-29 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 PIRSF PIRSF000238 1 507 9.5E-258 T 06-07-2017 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 Gene3D G3DSA:3.50.50.60 206 303 4.8E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 1 507 3.2E-241 T 06-07-2017 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 208 486 7.6E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 SUPERFAMILY SSF51905 193 503 3.48E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 210 229 1.1E-39 T 06-07-2017 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 457 479 1.1E-39 T 06-07-2017 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 347 365 1.1E-39 T 06-07-2017 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 305 323 1.1E-39 T 06-07-2017 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 431 447 1.1E-39 T 06-07-2017 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 Gene3D G3DSA:3.50.50.60 468 504 2.0E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS13465 87c82159ae5cca7344761917b1454112 507 Gene3D G3DSA:3.50.50.60 304 329 2.0E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS10410 81eab368785b3c3ff3233b6ef7f14242 486 Hamap MF_01670 Methylmalonate semialdehyde dehydrogenase [acylating] [iolA]. 4 486 72.24 T 06-07-2017 IPR023510 Methylmalonate-semialdehyde dehydrogenase, Gram-positive bacteria GO:0004491|GO:0018478|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373 GTHT12_RS10410 81eab368785b3c3ff3233b6ef7f14242 486 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 11 485 1.1E-192 T 06-07-2017 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 GTHT12_RS10410 81eab368785b3c3ff3233b6ef7f14242 486 Gene3D G3DSA:3.40.605.10 8 266 8.4E-101 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10410 81eab368785b3c3ff3233b6ef7f14242 486 SUPERFAMILY SSF53720 6 484 6.28E-158 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10410 81eab368785b3c3ff3233b6ef7f14242 486 Pfam PF00171 Aldehyde dehydrogenase family 18 482 3.4E-152 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10410 81eab368785b3c3ff3233b6ef7f14242 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10410 81eab368785b3c3ff3233b6ef7f14242 486 Gene3D G3DSA:3.40.309.10 267 454 1.8E-66 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 GTHT12_RS02445 c4218b3dcfec541817809f4dcb1bbc49 248 Pfam PF01903 CbiX 134 236 2.2E-24 T 06-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 GTHT12_RS02445 c4218b3dcfec541817809f4dcb1bbc49 248 Pfam PF01903 CbiX 9 113 6.3E-29 T 06-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 GTHT12_RS02445 c4218b3dcfec541817809f4dcb1bbc49 248 SUPERFAMILY SSF53800 1 238 6.76E-54 T 06-07-2017 GTHT12_RS02445 c4218b3dcfec541817809f4dcb1bbc49 248 Gene3D G3DSA:3.40.50.1400 1 118 1.2E-32 T 06-07-2017 GTHT12_RS02445 c4218b3dcfec541817809f4dcb1bbc49 248 Gene3D G3DSA:3.40.50.1400 128 241 1.1E-24 T 06-07-2017 GTHT12_RS18500 555fa98e5bdfd23f0a28d0b4504bed18 264 PIRSF PIRSF006648 22 255 2.8E-19 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 GTHT12_RS18500 555fa98e5bdfd23f0a28d0b4504bed18 264 Pfam PF01061 ABC-2 type transporter 21 217 6.0E-18 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 GTHT12_RS18500 555fa98e5bdfd23f0a28d0b4504bed18 264 PRINTS PR00164 ABC-2 type transport system membrane protein signature 195 214 5.6E-6 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 GTHT12_RS18500 555fa98e5bdfd23f0a28d0b4504bed18 264 PRINTS PR00164 ABC-2 type transport system membrane protein signature 175 194 5.6E-6 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 GTHT12_RS18500 555fa98e5bdfd23f0a28d0b4504bed18 264 PRINTS PR00164 ABC-2 type transport system membrane protein signature 138 162 5.6E-6 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 GTHT12_RS12345 ac48057d50cba1e16358439a7c980665 470 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 168 1.0E-54 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 GTHT12_RS12345 ac48057d50cba1e16358439a7c980665 470 Gene3D G3DSA:1.10.1040.10 180 434 8.6E-120 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 GTHT12_RS12345 ac48057d50cba1e16358439a7c980665 470 PIRSF PIRSF000109 1 470 7.0E-246 T 06-07-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 GTHT12_RS12345 ac48057d50cba1e16358439a7c980665 470 Gene3D G3DSA:1.20.5.320 437 468 1.2E-22 T 06-07-2017 IPR012284 6-phosphogluconate dehydrogenase, domain 3 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 GTHT12_RS12345 ac48057d50cba1e16358439a7c980665 470 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 253 265 - T 06-07-2017 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 GTHT12_RS12345 ac48057d50cba1e16358439a7c980665 470 Gene3D G3DSA:3.40.50.720 1 179 2.0E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS12345 ac48057d50cba1e16358439a7c980665 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 119 144 8.8E-89 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 GTHT12_RS12345 ac48057d50cba1e16358439a7c980665 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 167 195 8.8E-89 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 GTHT12_RS12345 ac48057d50cba1e16358439a7c980665 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 4 27 8.8E-89 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 GTHT12_RS12345 ac48057d50cba1e16358439a7c980665 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 66 95 8.8E-89 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 GTHT12_RS12345 ac48057d50cba1e16358439a7c980665 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 249 276 8.8E-89 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 GTHT12_RS12345 ac48057d50cba1e16358439a7c980665 470 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 357 379 8.8E-89 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 GTHT12_RS12345 ac48057d50cba1e16358439a7c980665 470 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 178 467 5.3E-136 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 GTHT12_RS12345 ac48057d50cba1e16358439a7c980665 470 SMART SM01350 178 468 6.8E-237 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 GTHT12_RS12345 ac48057d50cba1e16358439a7c980665 470 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 5 468 4.2E-233 T 06-07-2017 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 GTHT12_RS12345 ac48057d50cba1e16358439a7c980665 470 SUPERFAMILY SSF51735 4 176 1.84E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS12345 ac48057d50cba1e16358439a7c980665 470 SUPERFAMILY SSF48179 176 468 2.18E-136 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GTHT12_RS12460 938adf9cbc719e9eb75daef78036c8e9 82 Pfam PF11118 Protein of unknown function (DUF2627) 3 77 6.5E-37 T 06-07-2017 IPR020138 Uncharacterised protein family YqzF GTHT12_RS12460 938adf9cbc719e9eb75daef78036c8e9 82 ProDom PD058321 YQZF GSC13 TRANSMEMBRANE IG GKC13 MEMBRANE PROTEINS BH2767 RBL05544 SIMILAR 1 77 1.0E-17 T 06-07-2017 IPR020138 Uncharacterised protein family YqzF GTHT12_RS03610 f6fc8001ea23f37532d0905df84ed870 409 Pfam PF12698 ABC-2 family transporter protein 19 381 1.9E-55 T 06-07-2017 GTHT12_RS03610 f6fc8001ea23f37532d0905df84ed870 409 Gene3D G3DSA:3.40.190.10 46 134 1.1E-4 T 06-07-2017 GTHT12_RS03790 b8e3844138f0d59b0d01a744524b91d3 1242 SUPERFAMILY SSF52540 347 838 1.73E-120 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03790 b8e3844138f0d59b0d01a744524b91d3 1242 SUPERFAMILY SSF52540 8 204 1.73E-120 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03790 b8e3844138f0d59b0d01a744524b91d3 1242 SUPERFAMILY SSF52540 870 896 1.73E-120 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03790 b8e3844138f0d59b0d01a744524b91d3 1242 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 13 1239 0.0 T 06-07-2017 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 GTHT12_RS03790 b8e3844138f0d59b0d01a744524b91d3 1242 Gene3D G3DSA:3.40.50.300 357 468 1.4E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03790 b8e3844138f0d59b0d01a744524b91d3 1242 Gene3D G3DSA:3.40.50.300 13 171 1.4E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03790 b8e3844138f0d59b0d01a744524b91d3 1242 SUPERFAMILY SSF52980 1021 1235 4.45E-37 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 GTHT12_RS03790 b8e3844138f0d59b0d01a744524b91d3 1242 Pfam PF00580 UvrD/REP helicase N-terminal domain 14 467 2.5E-84 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 GTHT12_RS03790 b8e3844138f0d59b0d01a744524b91d3 1242 Gene3D G3DSA:3.40.50.300 482 618 1.4E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03790 b8e3844138f0d59b0d01a744524b91d3 1242 Gene3D G3DSA:3.40.50.300 789 951 1.4E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03790 b8e3844138f0d59b0d01a744524b91d3 1242 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 11 1241 19.855 T 06-07-2017 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 GTHT12_RS03790 b8e3844138f0d59b0d01a744524b91d3 1242 Gene3D G3DSA:3.90.320.10 1009 1234 4.8E-27 T 06-07-2017 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 GTHT12_RS03790 b8e3844138f0d59b0d01a744524b91d3 1242 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1060 1233 3.4E-9 T 06-07-2017 GTHT12_RS03790 b8e3844138f0d59b0d01a744524b91d3 1242 Gene3D G3DSA:1.10.486.10 625 775 5.1E-32 T 06-07-2017 GTHT12_RS03790 b8e3844138f0d59b0d01a744524b91d3 1242 Pfam PF13361 UvrD-like helicase C-terminal domain 478 892 2.1E-33 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 GTHT12_RS00750 045933b177980976ddfa92b071370ee4 62 SUPERFAMILY SSF55129 3 60 2.22E-23 T 06-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain GTHT12_RS00750 045933b177980976ddfa92b071370ee4 62 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 59 20.502 T 06-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 GTHT12_RS00750 045933b177980976ddfa92b071370ee4 62 PIRSF PIRSF002211 1 61 2.1E-31 T 06-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 GTHT12_RS00750 045933b177980976ddfa92b071370ee4 62 ProSitePatterns PS00634 Ribosomal protein L30 signature. 23 55 - T 06-07-2017 IPR018038 Ribosomal protein L30, conserved site GTHT12_RS00750 045933b177980976ddfa92b071370ee4 62 Pfam PF00327 Ribosomal protein L30p/L7e 5 55 8.4E-22 T 06-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain GTHT12_RS00750 045933b177980976ddfa92b071370ee4 62 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 6 59 7.0E-28 T 06-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 GTHT12_RS00750 045933b177980976ddfa92b071370ee4 62 Gene3D G3DSA:3.30.1390.20 2 60 1.8E-30 T 06-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain GTHT12_RS12280 80443fbb910f402e9f94a01a085de987 262 Pfam PF00106 short chain dehydrogenase 7 193 6.4E-58 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS12280 80443fbb910f402e9f94a01a085de987 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS12280 80443fbb910f402e9f94a01a085de987 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS12280 80443fbb910f402e9f94a01a085de987 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS12280 80443fbb910f402e9f94a01a085de987 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 9.3E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS12280 80443fbb910f402e9f94a01a085de987 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 9.3E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS12280 80443fbb910f402e9f94a01a085de987 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 9.3E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS12280 80443fbb910f402e9f94a01a085de987 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 9.3E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS12280 80443fbb910f402e9f94a01a085de987 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 9.3E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS12280 80443fbb910f402e9f94a01a085de987 262 PIRSF PIRSF000126 2 261 4.3E-55 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS12280 80443fbb910f402e9f94a01a085de987 262 SUPERFAMILY SSF51735 2 255 1.74E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS12280 80443fbb910f402e9f94a01a085de987 262 Gene3D G3DSA:3.40.50.720 4 232 8.7E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS12280 80443fbb910f402e9f94a01a085de987 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GTHT12_RS17870 856217c0a05c14a0b73121e6744bd196 377 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 2.7E-188 T 06-07-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 GTHT12_RS17870 856217c0a05c14a0b73121e6744bd196 377 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 1.6E-47 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal GTHT12_RS17870 856217c0a05c14a0b73121e6744bd196 377 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 06-07-2017 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 GTHT12_RS17870 856217c0a05c14a0b73121e6744bd196 377 SMART SM01003 4 136 2.8E-79 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal GTHT12_RS17870 856217c0a05c14a0b73121e6744bd196 377 Gene3D G3DSA:3.40.50.1770 1 168 6.3E-59 T 06-07-2017 GTHT12_RS17870 856217c0a05c14a0b73121e6744bd196 377 SMART SM01002 148 297 5.2E-90 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain GTHT12_RS17870 856217c0a05c14a0b73121e6744bd196 377 SUPERFAMILY SSF52283 305 360 1.45E-66 T 06-07-2017 GTHT12_RS17870 856217c0a05c14a0b73121e6744bd196 377 SUPERFAMILY SSF52283 1 136 1.45E-66 T 06-07-2017 GTHT12_RS17870 856217c0a05c14a0b73121e6744bd196 377 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 352 8.4E-85 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain GTHT12_RS17870 856217c0a05c14a0b73121e6744bd196 377 Gene3D G3DSA:3.40.50.720 169 303 1.1E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS17870 856217c0a05c14a0b73121e6744bd196 377 PIRSF PIRSF000183 1 371 8.7E-193 T 06-07-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 GTHT12_RS17870 856217c0a05c14a0b73121e6744bd196 377 SUPERFAMILY SSF51735 136 303 5.22E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS13995 fe6afdb1e1286110ab66fd1447478cbb 332 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 48 329 1.2E-77 T 06-07-2017 IPR010067 Aliphatic sulfonates-binding protein GO:0006790|GO:0006810|GO:0016020 GTHT12_RS13995 fe6afdb1e1286110ab66fd1447478cbb 332 Pfam PF09084 NMT1/THI5 like 88 265 2.8E-20 T 06-07-2017 IPR015168 SsuA/THI5-like GTHT12_RS13995 fe6afdb1e1286110ab66fd1447478cbb 332 Gene3D G3DSA:3.40.190.10 131 251 2.7E-33 T 06-07-2017 GTHT12_RS13995 fe6afdb1e1286110ab66fd1447478cbb 332 SUPERFAMILY SSF53850 46 279 5.32E-57 T 06-07-2017 GTHT12_RS13995 fe6afdb1e1286110ab66fd1447478cbb 332 SMART SM00062 47 263 2.5E-20 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF GTHT12_RS05695 36a9cef18ba8758b62ac3b557f5c3cc3 356 Gene3D G3DSA:2.60.40.420 126 274 2.4E-43 T 06-07-2017 IPR008972 Cupredoxin GTHT12_RS05695 36a9cef18ba8758b62ac3b557f5c3cc3 356 SUPERFAMILY SSF49503 128 282 2.21E-41 T 06-07-2017 IPR008972 Cupredoxin GTHT12_RS05695 36a9cef18ba8758b62ac3b557f5c3cc3 356 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 34 247 3.9E-55 T 06-07-2017 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05695 36a9cef18ba8758b62ac3b557f5c3cc3 356 Gene3D G3DSA:1.10.760.10 275 354 5.9E-19 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GTHT12_RS05695 36a9cef18ba8758b62ac3b557f5c3cc3 356 Pfam PF00034 Cytochrome c 262 354 1.1E-11 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GTHT12_RS05695 36a9cef18ba8758b62ac3b557f5c3cc3 356 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 176 230 - T 06-07-2017 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05695 36a9cef18ba8758b62ac3b557f5c3cc3 356 PRINTS PR01166 Cytochrome c oxidase subunit II signature 99 119 6.0E-8 T 06-07-2017 GTHT12_RS05695 36a9cef18ba8758b62ac3b557f5c3cc3 356 PRINTS PR01166 Cytochrome c oxidase subunit II signature 87 99 6.0E-8 T 06-07-2017 GTHT12_RS05695 36a9cef18ba8758b62ac3b557f5c3cc3 356 PRINTS PR01166 Cytochrome c oxidase subunit II signature 219 236 6.0E-8 T 06-07-2017 GTHT12_RS05695 36a9cef18ba8758b62ac3b557f5c3cc3 356 Gene3D G3DSA:1.10.287.90 30 116 1.6E-28 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05695 36a9cef18ba8758b62ac3b557f5c3cc3 356 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 156 234 3.5E-14 T 06-07-2017 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05695 36a9cef18ba8758b62ac3b557f5c3cc3 356 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 52 110 8.6E-11 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05695 36a9cef18ba8758b62ac3b557f5c3cc3 356 SUPERFAMILY SSF81464 16 120 1.96E-23 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05695 36a9cef18ba8758b62ac3b557f5c3cc3 356 SUPERFAMILY SSF46626 256 353 3.56E-18 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GTHT12_RS15295 da120f5269a57455d3d2c698cf40d289 121 Gene3D G3DSA:2.40.50.140 4 87 1.3E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS15295 da120f5269a57455d3d2c698cf40d289 121 PRINTS PR00681 Ribosomal protein S1 signature 59 77 3.0E-12 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 GTHT12_RS15295 da120f5269a57455d3d2c698cf40d289 121 PRINTS PR00681 Ribosomal protein S1 signature 20 39 3.0E-12 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 GTHT12_RS15295 da120f5269a57455d3d2c698cf40d289 121 SUPERFAMILY SSF50249 4 88 1.24E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS15295 da120f5269a57455d3d2c698cf40d289 121 SMART SM00316 5 76 1.4E-28 T 06-07-2017 IPR022967 RNA-binding domain, S1 GTHT12_RS15295 da120f5269a57455d3d2c698cf40d289 121 Pfam PF00575 S1 RNA binding domain 5 76 1.1E-23 T 06-07-2017 IPR003029 S1 domain GO:0003676 GTHT12_RS12045 6335ff085d62d6a497ef6b4b8474e2a1 177 Pfam PF07670 Nucleoside recognition 46 145 1.6E-5 T 06-07-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 GTHT12_RS08605 7179f78b4dd0018152200b0aa5587b8c 482 Gene3D G3DSA:1.20.210.10 3 468 8.9E-40 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS08605 7179f78b4dd0018152200b0aa5587b8c 482 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 8 451 1.0E-53 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS08605 7179f78b4dd0018152200b0aa5587b8c 482 SUPERFAMILY SSF81442 7 472 7.19E-65 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS06870 31fdfe3cb4826fdf9fddb990402541b1 444 SUPERFAMILY SSF55931 105 442 1.18E-130 T 06-07-2017 GTHT12_RS06870 31fdfe3cb4826fdf9fddb990402541b1 444 SMART SM01230 105 354 4.4E-139 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GTHT12_RS06870 31fdfe3cb4826fdf9fddb990402541b1 444 Gene3D G3DSA:3.10.20.70 6 108 8.3E-45 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GTHT12_RS06870 31fdfe3cb4826fdf9fddb990402541b1 444 Pfam PF00120 Glutamine synthetase, catalytic domain 106 440 1.8E-141 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GTHT12_RS06870 31fdfe3cb4826fdf9fddb990402541b1 444 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 361 373 - T 06-07-2017 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GTHT12_RS06870 31fdfe3cb4826fdf9fddb990402541b1 444 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 06-07-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 GTHT12_RS06870 31fdfe3cb4826fdf9fddb990402541b1 444 SUPERFAMILY SSF54368 5 104 5.89E-36 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GTHT12_RS06870 31fdfe3cb4826fdf9fddb990402541b1 444 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 441 3.2E-185 T 06-07-2017 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GTHT12_RS06870 31fdfe3cb4826fdf9fddb990402541b1 444 Gene3D G3DSA:3.30.590.10 109 431 6.5E-130 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 GTHT12_RS06870 31fdfe3cb4826fdf9fddb990402541b1 444 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 98 1.2E-33 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GTHT12_RS06870 31fdfe3cb4826fdf9fddb990402541b1 444 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 06-07-2017 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 GTHT12_RS00415 3da159b112b11342b34d3edefd22408f 284 Gene3D G3DSA:3.20.20.20 9 276 4.9E-118 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GTHT12_RS00415 3da159b112b11342b34d3edefd22408f 284 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 26 41 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GTHT12_RS00415 3da159b112b11342b34d3edefd22408f 284 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 60 73 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GTHT12_RS00415 3da159b112b11342b34d3edefd22408f 284 SUPERFAMILY SSF51717 12 277 1.31E-104 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GTHT12_RS00415 3da159b112b11342b34d3edefd22408f 284 Pfam PF00809 Pterin binding enzyme 27 260 5.6E-90 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GTHT12_RS00415 3da159b112b11342b34d3edefd22408f 284 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 26 275 2.7E-101 T 06-07-2017 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 GTHT12_RS09380 af924389a9b95b97f7a44e1aed4bc59b 302 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 289 1.0E-143 T 06-07-2017 GTHT12_RS09380 af924389a9b95b97f7a44e1aed4bc59b 302 Pfam PF04204 Homoserine O-succinyltransferase 2 299 1.7E-144 T 06-07-2017 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 GTHT12_RS09380 af924389a9b95b97f7a44e1aed4bc59b 302 Hamap MF_00295 Homoserine O-succinyltransferase [metA]. 1 301 55.499 T 06-07-2017 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 GTHT12_RS09380 af924389a9b95b97f7a44e1aed4bc59b 302 PIRSF PIRSF000450 1 302 7.8E-151 T 06-07-2017 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 GTHT12_RS09380 af924389a9b95b97f7a44e1aed4bc59b 302 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 300 1.7E-135 T 06-07-2017 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 GTHT12_RS09380 af924389a9b95b97f7a44e1aed4bc59b 302 Gene3D G3DSA:3.40.50.880 34 299 1.1E-127 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS09380 af924389a9b95b97f7a44e1aed4bc59b 302 SUPERFAMILY SSF52317 17 297 3.15E-105 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS14630 b7a1eb5fef71fb08ef82c34825dc6d8d 1056 Pfam PF01580 FtsK/SpoIIIE family 683 816 5.2E-46 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 GTHT12_RS14630 b7a1eb5fef71fb08ef82c34825dc6d8d 1056 Pfam PF01580 FtsK/SpoIIIE family 820 875 5.4E-16 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 GTHT12_RS14630 b7a1eb5fef71fb08ef82c34825dc6d8d 1056 Pfam PF09397 Ftsk gamma domain 971 1032 2.8E-29 T 06-07-2017 IPR018541 FtsK gamma domain GTHT12_RS14630 b7a1eb5fef71fb08ef82c34825dc6d8d 1056 SMART SM00843 970 1035 1.7E-40 T 06-07-2017 IPR018541 FtsK gamma domain GTHT12_RS14630 b7a1eb5fef71fb08ef82c34825dc6d8d 1056 SUPERFAMILY SSF52540 657 945 1.73E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS14630 b7a1eb5fef71fb08ef82c34825dc6d8d 1056 Gene3D G3DSA:3.40.50.300 656 941 1.1E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS14630 b7a1eb5fef71fb08ef82c34825dc6d8d 1056 SUPERFAMILY SSF46785 971 1037 3.24E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS05600 b7531def689cd6a762b45da7f8adde5a 125 Pfam PF08968 Domain of unknown function (DUF1885) 3 123 1.4E-48 T 06-07-2017 IPR015062 Protein of unknown function DUF1885 GTHT12_RS05600 b7531def689cd6a762b45da7f8adde5a 125 Gene3D G3DSA:3.30.310.120 46 123 3.1E-37 T 06-07-2017 GTHT12_RS05600 b7531def689cd6a762b45da7f8adde5a 125 SUPERFAMILY SSF111171 2 122 8.5E-60 T 06-07-2017 IPR015062 Protein of unknown function DUF1885 GTHT12_RS05600 b7531def689cd6a762b45da7f8adde5a 125 Gene3D G3DSA:1.20.5.850 2 45 2.0E-21 T 06-07-2017 GTHT12_RS01735 7fb278ddb8aafd559d9418508306fbe6 292 Pfam PF13612 Transposase DDE domain 111 267 5.1E-26 T 06-07-2017 IPR025668 Transposase DDE domain GTHT12_RS10110 ae31082ba36d7a397e87ba441313c588 202 Pfam PF01470 Pyroglutamyl peptidase 2 200 4.7E-62 T 06-07-2017 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like GTHT12_RS10110 ae31082ba36d7a397e87ba441313c588 202 Gene3D G3DSA:3.40.630.20 2 200 5.2E-58 T 06-07-2017 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like GTHT12_RS10110 ae31082ba36d7a397e87ba441313c588 202 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 69 85 - T 06-07-2017 IPR033693 Pyroglutamyl peptidase I, Glu active site GTHT12_RS10110 ae31082ba36d7a397e87ba441313c588 202 SUPERFAMILY SSF53182 1 200 3.01E-62 T 06-07-2017 GTHT12_RS10110 ae31082ba36d7a397e87ba441313c588 202 PIRSF PIRSF015592 1 202 4.2E-70 T 06-07-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 GTHT12_RS10110 ae31082ba36d7a397e87ba441313c588 202 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 4 27 1.0E-24 T 06-07-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 GTHT12_RS10110 ae31082ba36d7a397e87ba441313c588 202 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 161 173 1.0E-24 T 06-07-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 GTHT12_RS10110 ae31082ba36d7a397e87ba441313c588 202 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 80 100 1.0E-24 T 06-07-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 GTHT12_RS10110 ae31082ba36d7a397e87ba441313c588 202 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 131 147 1.0E-24 T 06-07-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 GTHT12_RS10110 ae31082ba36d7a397e87ba441313c588 202 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 62 74 1.0E-24 T 06-07-2017 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 GTHT12_RS12605 79f15caac9aa6586d69259954eeb967d 185 SMART SM01185 67 121 9.4E-28 T 06-07-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 GTHT12_RS12605 79f15caac9aa6586d69259954eeb967d 185 PIRSF PIRSF005901 1 185 8.1E-73 T 06-07-2017 IPR020599 Translation elongation factor P/YeiP GTHT12_RS12605 79f15caac9aa6586d69259954eeb967d 185 SUPERFAMILY SSF50249 128 185 6.0E-19 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS12605 79f15caac9aa6586d69259954eeb967d 185 SUPERFAMILY SSF50104 1 63 8.42E-23 T 06-07-2017 IPR008991 Translation protein SH3-like domain GTHT12_RS12605 79f15caac9aa6586d69259954eeb967d 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 51.82 T 06-07-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 GTHT12_RS12605 79f15caac9aa6586d69259954eeb967d 185 SMART SM00841 129 184 2.6E-35 T 06-07-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 GTHT12_RS12605 79f15caac9aa6586d69259954eeb967d 185 SUPERFAMILY SSF50249 65 129 1.88E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS12605 79f15caac9aa6586d69259954eeb967d 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 1.3E-82 T 06-07-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 GTHT12_RS12605 79f15caac9aa6586d69259954eeb967d 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 3.5E-29 T 06-07-2017 IPR013185 Translation elongation factor, KOW-like GTHT12_RS12605 79f15caac9aa6586d69259954eeb967d 185 Gene3D G3DSA:2.40.50.140 128 185 1.1E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS12605 79f15caac9aa6586d69259954eeb967d 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 06-07-2017 IPR013852 Translation elongation factor P/YeiP, conserved site GTHT12_RS12605 79f15caac9aa6586d69259954eeb967d 185 Gene3D G3DSA:2.40.50.140 65 127 2.2E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS12605 79f15caac9aa6586d69259954eeb967d 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 2.9E-23 T 06-07-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 GTHT12_RS12605 79f15caac9aa6586d69259954eeb967d 185 Gene3D G3DSA:2.30.30.30 1 63 1.5E-33 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 GTHT12_RS12605 79f15caac9aa6586d69259954eeb967d 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 5.5E-27 T 06-07-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 GTHT12_RS00630 e22108ef58f7ebc8cf491832125dc7db 82 Gene3D G3DSA:3.30.1330.30 5 81 4.8E-16 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like GTHT12_RS00630 e22108ef58f7ebc8cf491832125dc7db 82 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 5 81 1.0E-16 T 06-07-2017 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 GTHT12_RS00630 e22108ef58f7ebc8cf491832125dc7db 82 Hamap MF_00574 Putative ribosomal protein L7Ae-like. 2 82 24.745 T 06-07-2017 IPR023460 Ribosomal protein L7Ae, putative GTHT12_RS00630 e22108ef58f7ebc8cf491832125dc7db 82 SUPERFAMILY SSF55315 4 81 4.99E-21 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like GTHT12_RS17910 075371eac9f40cf6f27cc4f3eaf7553b 648 SUPERFAMILY SSF81442 41 551 3.01E-185 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17910 075371eac9f40cf6f27cc4f3eaf7553b 648 Gene3D G3DSA:1.20.210.10 36 582 8.5E-195 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17910 075371eac9f40cf6f27cc4f3eaf7553b 648 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 45 550 8.4E-205 T 06-07-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 GTHT12_RS17910 075371eac9f40cf6f27cc4f3eaf7553b 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 192 210 4.7E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17910 075371eac9f40cf6f27cc4f3eaf7553b 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 91 114 4.7E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17910 075371eac9f40cf6f27cc4f3eaf7553b 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 342 363 4.7E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17910 075371eac9f40cf6f27cc4f3eaf7553b 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 160 172 4.7E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17910 075371eac9f40cf6f27cc4f3eaf7553b 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 318 333 4.7E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17910 075371eac9f40cf6f27cc4f3eaf7553b 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 221 240 4.7E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17910 075371eac9f40cf6f27cc4f3eaf7553b 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 455 476 4.7E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17910 075371eac9f40cf6f27cc4f3eaf7553b 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 118 142 4.7E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17910 075371eac9f40cf6f27cc4f3eaf7553b 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 405 424 4.7E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17910 075371eac9f40cf6f27cc4f3eaf7553b 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 44 69 4.7E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17910 075371eac9f40cf6f27cc4f3eaf7553b 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 377 395 4.7E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17910 075371eac9f40cf6f27cc4f3eaf7553b 648 PRINTS PR01165 Cytochrome c oxidase subunit I signature 272 293 4.7E-102 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17910 075371eac9f40cf6f27cc4f3eaf7553b 648 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 53 499 3.5E-148 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17910 075371eac9f40cf6f27cc4f3eaf7553b 648 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 274 328 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17910 075371eac9f40cf6f27cc4f3eaf7553b 648 TIGRFAM TIGR02882 QoxB: cytochrome aa3 quinol oxidase, subunit I 2 643 0.0 T 06-07-2017 IPR014233 Quinol oxidase subunit I GO:0005507|GO:0016021|GO:0016682|GO:0020037|GO:0055114 GTHT12_RS17045 b57bf10a5fb88aa2656eac99e74ff13c 150 Pfam PF00583 Acetyltransferase (GNAT) family 46 117 1.8E-12 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS17045 b57bf10a5fb88aa2656eac99e74ff13c 150 Gene3D G3DSA:3.40.630.30 1 149 1.8E-31 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS17045 b57bf10a5fb88aa2656eac99e74ff13c 150 SUPERFAMILY SSF55729 1 149 2.45E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS03870 0444991b9caef52a9e3d5a2d8faedf87 946 SUPERFAMILY SSF141868 697 943 9.94E-89 T 06-07-2017 IPR001633 EAL domain GTHT12_RS03870 0444991b9caef52a9e3d5a2d8faedf87 946 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 518 678 4.5E-33 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS03870 0444991b9caef52a9e3d5a2d8faedf87 946 Pfam PF00990 Diguanylate cyclase, GGDEF domain 519 676 4.0E-39 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS03870 0444991b9caef52a9e3d5a2d8faedf87 946 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 394 514 2.1E-24 T 06-07-2017 IPR000014 PAS domain GTHT12_RS03870 0444991b9caef52a9e3d5a2d8faedf87 946 Pfam PF00563 EAL domain 698 932 1.7E-79 T 06-07-2017 IPR001633 EAL domain GTHT12_RS03870 0444991b9caef52a9e3d5a2d8faedf87 946 SMART SM00897 25 206 1.1E-19 T 06-07-2017 IPR013702 FIST domain, N-terminal GTHT12_RS03870 0444991b9caef52a9e3d5a2d8faedf87 946 SMART SM00091 396 462 1.4E-9 T 06-07-2017 IPR000014 PAS domain GTHT12_RS03870 0444991b9caef52a9e3d5a2d8faedf87 946 Pfam PF13426 PAS domain 410 507 7.4E-9 T 06-07-2017 IPR000014 PAS domain GTHT12_RS03870 0444991b9caef52a9e3d5a2d8faedf87 946 Gene3D G3DSA:3.30.450.20 389 506 3.5E-25 T 06-07-2017 GTHT12_RS03870 0444991b9caef52a9e3d5a2d8faedf87 946 Gene3D G3DSA:3.30.70.270 520 688 3.8E-48 T 06-07-2017 GTHT12_RS03870 0444991b9caef52a9e3d5a2d8faedf87 946 SUPERFAMILY SSF55073 525 680 1.33E-40 T 06-07-2017 IPR029787 Nucleotide cyclase GTHT12_RS03870 0444991b9caef52a9e3d5a2d8faedf87 946 Gene3D G3DSA:3.20.20.450 693 943 4.7E-98 T 06-07-2017 IPR001633 EAL domain GTHT12_RS03870 0444991b9caef52a9e3d5a2d8faedf87 946 Pfam PF08495 FIST N domain 35 205 6.8E-13 T 06-07-2017 IPR013702 FIST domain, N-terminal GTHT12_RS03870 0444991b9caef52a9e3d5a2d8faedf87 946 SUPERFAMILY SSF55785 384 506 1.92E-24 T 06-07-2017 IPR000014 PAS domain GTHT12_RS03870 0444991b9caef52a9e3d5a2d8faedf87 946 SMART SM00052 690 937 4.8E-112 T 06-07-2017 IPR001633 EAL domain GTHT12_RS03870 0444991b9caef52a9e3d5a2d8faedf87 946 SMART SM00267 508 680 2.7E-47 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS18310 9585b6722a613eb38e7ecffc2975bd9d 139 Gene3D G3DSA:3.40.960.10 46 97 4.1E-5 T 06-07-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 GTHT12_RS18310 9585b6722a613eb38e7ecffc2975bd9d 139 Pfam PF04480 Protein of unknown function (DUF559) 46 137 4.7E-13 T 06-07-2017 IPR007569 Domain of unknown function DUF559 GTHT12_RS18310 9585b6722a613eb38e7ecffc2975bd9d 139 SUPERFAMILY SSF52980 41 137 1.23E-16 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 GTHT12_RS09770 2234e7f0e2b43c4b0fe948d00b3eba8b 101 SUPERFAMILY SSF46955 17 81 2.43E-16 T 06-07-2017 IPR009061 Putative DNA-binding domain GTHT12_RS09770 2234e7f0e2b43c4b0fe948d00b3eba8b 101 Pfam PF13411 MerR HTH family regulatory protein 17 81 1.1E-15 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS09770 2234e7f0e2b43c4b0fe948d00b3eba8b 101 Gene3D G3DSA:1.10.1660.10 17 86 3.8E-18 T 06-07-2017 GTHT12_RS09770 2234e7f0e2b43c4b0fe948d00b3eba8b 101 SMART SM00422 16 83 3.4E-16 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS06735 bd8c2cdffecb293c790b5d429e2301d5 307 Gene3D G3DSA:3.20.20.140 1 303 8.9E-97 T 06-07-2017 GTHT12_RS06735 bd8c2cdffecb293c790b5d429e2301d5 307 SUPERFAMILY SSF51556 1 307 1.63E-78 T 06-07-2017 IPR032466 Metal-dependent hydrolase GTHT12_RS06735 bd8c2cdffecb293c790b5d429e2301d5 307 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 306 1.8E-96 T 06-07-2017 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 GTHT12_RS06610 6725eb408385a8bbd82e3449a33b569d 347 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 238 252 - T 06-07-2017 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 GTHT12_RS06610 6725eb408385a8bbd82e3449a33b569d 347 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 8 119 9.6E-35 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 GTHT12_RS06610 6725eb408385a8bbd82e3449a33b569d 347 Gene3D G3DSA:3.30.360.10 144 324 2.3E-81 T 06-07-2017 GTHT12_RS06610 6725eb408385a8bbd82e3449a33b569d 347 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 7 343 4.4E-157 T 06-07-2017 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 GTHT12_RS06610 6725eb408385a8bbd82e3449a33b569d 347 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 5 342 38.493 T 06-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 GTHT12_RS06610 6725eb408385a8bbd82e3449a33b569d 347 SUPERFAMILY SSF51735 6 157 9.56E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS06610 6725eb408385a8bbd82e3449a33b569d 347 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 140 328 2.8E-57 T 06-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 GTHT12_RS06610 6725eb408385a8bbd82e3449a33b569d 347 Gene3D G3DSA:3.40.50.720 3 143 3.0E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS06610 6725eb408385a8bbd82e3449a33b569d 347 SUPERFAMILY SSF55347 130 329 2.36E-75 T 06-07-2017 GTHT12_RS06610 6725eb408385a8bbd82e3449a33b569d 347 SMART SM00859 7 122 7.4E-45 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 GTHT12_RS06610 6725eb408385a8bbd82e3449a33b569d 347 PIRSF PIRSF000148 5 347 2.0E-132 T 06-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 GTHT12_RS18530 b2746c245f2c3a6d0b47e66170f08c2b 335 SUPERFAMILY SSF50494 108 330 4.01E-31 T 06-07-2017 IPR009003 Peptidase S1, PA clan GTHT12_RS18530 b2746c245f2c3a6d0b47e66170f08c2b 335 PRINTS PR00839 V8 serine protease family signature 146 163 8.7E-23 T 06-07-2017 IPR008256 Peptidase S1B GO:0006508|GO:0008236 GTHT12_RS18530 b2746c245f2c3a6d0b47e66170f08c2b 335 PRINTS PR00839 V8 serine protease family signature 118 135 8.7E-23 T 06-07-2017 IPR008256 Peptidase S1B GO:0006508|GO:0008236 GTHT12_RS18530 b2746c245f2c3a6d0b47e66170f08c2b 335 PRINTS PR00839 V8 serine protease family signature 241 254 8.7E-23 T 06-07-2017 IPR008256 Peptidase S1B GO:0006508|GO:0008236 GTHT12_RS18530 b2746c245f2c3a6d0b47e66170f08c2b 335 PRINTS PR00839 V8 serine protease family signature 278 294 8.7E-23 T 06-07-2017 IPR008256 Peptidase S1B GO:0006508|GO:0008236 GTHT12_RS18530 b2746c245f2c3a6d0b47e66170f08c2b 335 PRINTS PR00839 V8 serine protease family signature 295 307 8.7E-23 T 06-07-2017 IPR008256 Peptidase S1B GO:0006508|GO:0008236 GTHT12_RS18530 b2746c245f2c3a6d0b47e66170f08c2b 335 Pfam PF00089 Trypsin 127 327 4.4E-15 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 GTHT12_RS18530 b2746c245f2c3a6d0b47e66170f08c2b 335 Gene3D G3DSA:2.40.10.10 228 309 3.1E-15 T 06-07-2017 GTHT12_RS18530 b2746c245f2c3a6d0b47e66170f08c2b 335 Gene3D G3DSA:2.40.10.10 139 227 4.7E-19 T 06-07-2017 GTHT12_RS17520 a5eae35dd27c70edbb523e8dfeff5fb4 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 49.223 T 06-07-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 GTHT12_RS17520 a5eae35dd27c70edbb523e8dfeff5fb4 209 Gene3D G3DSA:3.40.50.2020 3 209 7.1E-86 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS17520 a5eae35dd27c70edbb523e8dfeff5fb4 209 SUPERFAMILY SSF53271 4 207 7.87E-76 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS17520 a5eae35dd27c70edbb523e8dfeff5fb4 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 1.0E-75 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS17520 a5eae35dd27c70edbb523e8dfeff5fb4 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 209 5.9E-94 T 06-07-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 GTHT12_RS05070 0a17f522f1cb13568a4e0d16c04efa20 153 Gene3D G3DSA:1.10.10.10 2 143 1.3E-39 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS05070 0a17f522f1cb13568a4e0d16c04efa20 153 SUPERFAMILY SSF46785 9 144 4.62E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS05070 0a17f522f1cb13568a4e0d16c04efa20 153 SMART SM00347 31 131 4.3E-25 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS05070 0a17f522f1cb13568a4e0d16c04efa20 153 Pfam PF01047 MarR family 39 95 2.2E-16 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS05070 0a17f522f1cb13568a4e0d16c04efa20 153 ProSitePatterns PS01117 MarR-type HTH domain signature. 70 104 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site GTHT12_RS05070 0a17f522f1cb13568a4e0d16c04efa20 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 107 3.6E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS05070 0a17f522f1cb13568a4e0d16c04efa20 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 87 3.6E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS05070 0a17f522f1cb13568a4e0d16c04efa20 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 121 141 3.6E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 PRINTS PR00418 DNA topoisomerase II family signature 40 55 3.5E-75 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 PRINTS PR00418 DNA topoisomerase II family signature 426 440 3.5E-75 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 PRINTS PR00418 DNA topoisomerase II family signature 118 132 3.5E-75 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 PRINTS PR00418 DNA topoisomerase II family signature 530 542 3.5E-75 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 PRINTS PR00418 DNA topoisomerase II family signature 75 88 3.5E-75 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 PRINTS PR00418 DNA topoisomerase II family signature 510 527 3.5E-75 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 PRINTS PR00418 DNA topoisomerase II family signature 572 588 3.5E-75 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 PRINTS PR00418 DNA topoisomerase II family signature 274 287 3.5E-75 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 PRINTS PR00418 DNA topoisomerase II family signature 492 508 3.5E-75 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 SUPERFAMILY SSF55874 11 221 9.3E-76 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 SMART SM00433 40 633 0.0 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 Gene3D G3DSA:3.30.230.10 226 398 5.5E-75 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 ProSitePatterns PS00177 DNA topoisomerase II signature. 428 436 - T 06-07-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 569 629 2.7E-31 T 06-07-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 SUPERFAMILY SSF54211 227 397 1.56E-62 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 11 640 0.0 T 06-07-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 Pfam PF00204 DNA gyrase B 227 396 2.6E-63 T 06-07-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 38 179 1.7E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 Gene3D G3DSA:3.40.50.670 410 622 8.8E-102 T 06-07-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 SMART SM00387 36 180 1.9E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 PRINTS PR01159 DNA gyrase subunit B signature 201 214 1.5E-79 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 PRINTS PR01159 DNA gyrase subunit B signature 609 625 1.5E-79 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 PRINTS PR01159 DNA gyrase subunit B signature 226 248 1.5E-79 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 PRINTS PR01159 DNA gyrase subunit B signature 380 400 1.5E-79 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 PRINTS PR01159 DNA gyrase subunit B signature 476 485 1.5E-79 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 PRINTS PR01159 DNA gyrase subunit B signature 366 380 1.5E-79 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 PRINTS PR01159 DNA gyrase subunit B signature 186 201 1.5E-79 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 PRINTS PR01159 DNA gyrase subunit B signature 593 605 1.5E-79 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 PRINTS PR01159 DNA gyrase subunit B signature 318 334 1.5E-79 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 PRINTS PR01159 DNA gyrase subunit B signature 11 21 1.5E-79 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 Gene3D G3DSA:3.30.565.10 11 220 6.0E-96 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 SUPERFAMILY SSF56719 400 631 2.22E-94 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 Pfam PF01751 Toprim domain 425 534 3.0E-19 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS00025 a8a40ffdd88082eb0cf33585aaf60984 640 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 8 640 100.234 T 06-07-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 GTHT12_RS13370 da4c87c54d718cea29fd42e13f61a9c7 138 SUPERFAMILY SSF53098 1 137 4.4E-46 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS13370 da4c87c54d718cea29fd42e13f61a9c7 138 Gene3D G3DSA:3.30.420.140 1 138 9.2E-53 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 GTHT12_RS13370 da4c87c54d718cea29fd42e13f61a9c7 138 SMART SM00732 1 103 1.2E-39 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 GTHT12_RS13370 da4c87c54d718cea29fd42e13f61a9c7 138 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 135 2.3E-50 T 06-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 GTHT12_RS13370 da4c87c54d718cea29fd42e13f61a9c7 138 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 138 28.102 T 06-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 GTHT12_RS13370 da4c87c54d718cea29fd42e13f61a9c7 138 Pfam PF03652 Holliday junction resolvase 1 136 5.8E-46 T 06-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 GTHT12_RS02515 ef73f8b142fa854f3c3488bcb1534c62 515 Gene3D G3DSA:3.20.130.10 316 496 3.0E-70 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 GTHT12_RS02515 ef73f8b142fa854f3c3488bcb1534c62 515 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 8 281 6.5E-64 T 06-07-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 GTHT12_RS02515 ef73f8b142fa854f3c3488bcb1534c62 515 Pfam PF05681 Fumarate hydratase (Fumerase) 6 282 4.5E-75 T 06-07-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 GTHT12_RS02515 ef73f8b142fa854f3c3488bcb1534c62 515 SUPERFAMILY SSF117457 328 496 1.83E-52 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 GTHT12_RS02515 ef73f8b142fa854f3c3488bcb1534c62 515 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 334 496 1.0E-51 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 GTHT12_RS02515 ef73f8b142fa854f3c3488bcb1534c62 515 PIRSF PIRSF001394 1 514 4.0E-197 T 06-07-2017 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 GTHT12_RS02515 ef73f8b142fa854f3c3488bcb1534c62 515 Pfam PF05683 Fumarase C-terminus 289 497 3.3E-61 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 GTHT12_RS01480 b820692d2e2edc18dcf2978bfa677bd1 94 SUPERFAMILY SSF50129 2 93 8.12E-36 T 06-07-2017 IPR011032 GroES-like GTHT12_RS01480 b820692d2e2edc18dcf2978bfa677bd1 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 26 - T 06-07-2017 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 GTHT12_RS01480 b820692d2e2edc18dcf2978bfa677bd1 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 1.9E-37 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 GTHT12_RS01480 b820692d2e2edc18dcf2978bfa677bd1 94 PRINTS PR00297 10kDa chaperonin signature 24 45 1.6E-33 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 GTHT12_RS01480 b820692d2e2edc18dcf2978bfa677bd1 94 PRINTS PR00297 10kDa chaperonin signature 59 71 1.6E-33 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 GTHT12_RS01480 b820692d2e2edc18dcf2978bfa677bd1 94 PRINTS PR00297 10kDa chaperonin signature 2 17 1.6E-33 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 GTHT12_RS01480 b820692d2e2edc18dcf2978bfa677bd1 94 PRINTS PR00297 10kDa chaperonin signature 80 93 1.6E-33 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 GTHT12_RS01480 b820692d2e2edc18dcf2978bfa677bd1 94 SMART SM00883 1 93 1.5E-57 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 GTHT12_RS01480 b820692d2e2edc18dcf2978bfa677bd1 94 Hamap MF_00580 10 kDa chaperonin [groS]. 1 94 27.839 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 GTHT12_RS01480 b820692d2e2edc18dcf2978bfa677bd1 94 Gene3D G3DSA:2.30.33.40 2 93 1.2E-39 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 GTHT12_RS02480 b14c6888a603dcb2ce93089f27697e60 160 SMART SM00226 2 149 4.3E-56 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily GTHT12_RS02480 b14c6888a603dcb2ce93089f27697e60 160 SUPERFAMILY SSF52788 1 150 1.57E-52 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily GTHT12_RS02480 b14c6888a603dcb2ce93089f27697e60 160 Gene3D G3DSA:3.40.50.270 1 152 8.6E-57 T 06-07-2017 GTHT12_RS02480 b14c6888a603dcb2ce93089f27697e60 160 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 147 2.8E-42 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily GTHT12_RS02480 b14c6888a603dcb2ce93089f27697e60 160 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 1.7E-17 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 GTHT12_RS02480 b14c6888a603dcb2ce93089f27697e60 160 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 123 138 1.7E-17 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 GTHT12_RS02480 b14c6888a603dcb2ce93089f27697e60 160 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 47 63 1.7E-17 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 GTHT12_RS02480 b14c6888a603dcb2ce93089f27697e60 160 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 81 96 1.7E-17 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 GTHT12_RS18870 5551ef8a728601c9c63c75412ad7c90f 217 Pfam PF12161 HsdM N-terminal domain 13 138 2.2E-29 T 06-07-2017 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain GTHT12_RS18870 5551ef8a728601c9c63c75412ad7c90f 217 Pfam PF02384 N-6 DNA Methylase 150 217 9.7E-24 T 06-07-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 GTHT12_RS18870 5551ef8a728601c9c63c75412ad7c90f 217 SUPERFAMILY SSF53335 11 216 6.35E-56 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS18870 5551ef8a728601c9c63c75412ad7c90f 217 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 174 190 5.8E-7 T 06-07-2017 GTHT12_RS18870 5551ef8a728601c9c63c75412ad7c90f 217 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 198 212 5.8E-7 T 06-07-2017 GTHT12_RS18870 5551ef8a728601c9c63c75412ad7c90f 217 Gene3D G3DSA:3.40.50.150 176 216 2.7E-9 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS08350 1b0ec142e61c0e2a7679bc8b583de59a 541 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 48 511 1.4E-192 T 06-07-2017 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 GTHT12_RS08350 1b0ec142e61c0e2a7679bc8b583de59a 541 PIRSF PIRSF005690 33 526 1.1E-192 T 06-07-2017 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 GTHT12_RS15410 b620cfff7d5e6265671dbfe72f81b810 167 Gene3D G3DSA:3.90.79.10 8 123 3.6E-27 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 GTHT12_RS15410 b620cfff7d5e6265671dbfe72f81b810 167 Pfam PF00293 NUDIX domain 11 118 5.6E-18 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 GTHT12_RS15410 b620cfff7d5e6265671dbfe72f81b810 167 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 GTHT12_RS15410 b620cfff7d5e6265671dbfe72f81b810 167 PRINTS PR00502 NUDIX hydrolase family signature 37 51 1.1E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 GTHT12_RS15410 b620cfff7d5e6265671dbfe72f81b810 167 PRINTS PR00502 NUDIX hydrolase family signature 51 66 1.1E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 GTHT12_RS15410 b620cfff7d5e6265671dbfe72f81b810 167 SUPERFAMILY SSF55811 7 130 2.3E-25 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 GTHT12_RS17200 29a0f9d5fd7df64495a0a6b7f191de41 843 SMART SM00849 387 584 7.2E-18 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS17200 29a0f9d5fd7df64495a0a6b7f191de41 843 Gene3D G3DSA:1.25.40.10 41 122 5.1E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS17200 29a0f9d5fd7df64495a0a6b7f191de41 843 Gene3D G3DSA:1.25.40.10 158 217 5.1E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS17200 29a0f9d5fd7df64495a0a6b7f191de41 843 Gene3D G3DSA:3.60.15.10 374 627 3.0E-49 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS17200 29a0f9d5fd7df64495a0a6b7f191de41 843 Pfam PF00753 Metallo-beta-lactamase superfamily 387 548 2.4E-13 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS17200 29a0f9d5fd7df64495a0a6b7f191de41 843 SMART SM01027 615 737 6.4E-12 T 06-07-2017 IPR022712 Beta-Casp domain GTHT12_RS17200 29a0f9d5fd7df64495a0a6b7f191de41 843 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 752 794 3.7E-7 T 06-07-2017 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain GTHT12_RS17200 29a0f9d5fd7df64495a0a6b7f191de41 843 SUPERFAMILY SSF48452 44 111 2.2E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS17200 29a0f9d5fd7df64495a0a6b7f191de41 843 SUPERFAMILY SSF48452 167 212 2.2E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS17200 29a0f9d5fd7df64495a0a6b7f191de41 843 Pfam PF10996 Beta-Casp domain 615 737 3.6E-14 T 06-07-2017 IPR022712 Beta-Casp domain GTHT12_RS17200 29a0f9d5fd7df64495a0a6b7f191de41 843 SUPERFAMILY SSF56281 373 796 9.48E-95 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS01850 90b588552f4c6fd0a09f3352db4e5662 547 Pfam PF00501 AMP-binding enzyme 29 441 8.9E-98 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GTHT12_RS01850 90b588552f4c6fd0a09f3352db4e5662 547 Gene3D G3DSA:3.40.50.980 22 200 1.1E-36 T 06-07-2017 GTHT12_RS01850 90b588552f4c6fd0a09f3352db4e5662 547 ProSitePatterns PS00455 Putative AMP-binding domain signature. 195 206 - T 06-07-2017 IPR020845 AMP-binding, conserved site GTHT12_RS01850 90b588552f4c6fd0a09f3352db4e5662 547 Pfam PF13193 AMP-binding enzyme C-terminal domain 451 527 1.3E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain GTHT12_RS01850 90b588552f4c6fd0a09f3352db4e5662 547 Gene3D G3DSA:3.30.300.30 436 537 1.6E-24 T 06-07-2017 GTHT12_RS01850 90b588552f4c6fd0a09f3352db4e5662 547 SUPERFAMILY SSF56801 17 538 1.03E-143 T 06-07-2017 GTHT12_RS01850 90b588552f4c6fd0a09f3352db4e5662 547 Gene3D G3DSA:2.30.38.10 362 435 1.9E-24 T 06-07-2017 GTHT12_RS01850 90b588552f4c6fd0a09f3352db4e5662 547 Gene3D G3DSA:3.40.50.980 201 354 5.6E-39 T 06-07-2017 GTHT12_RS00745 ada1b8904f405cf47e7b163c9fdfc1f9 166 Gene3D G3DSA:3.30.230.10 76 159 3.7E-35 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GTHT12_RS00745 ada1b8904f405cf47e7b163c9fdfc1f9 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 37.175 T 06-07-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 GTHT12_RS00745 ada1b8904f405cf47e7b163c9fdfc1f9 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 9 163 7.2E-74 T 06-07-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 GTHT12_RS00745 ada1b8904f405cf47e7b163c9fdfc1f9 166 SUPERFAMILY SSF54211 80 159 2.5E-27 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS00745 ada1b8904f405cf47e7b163c9fdfc1f9 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 75 2.5E-33 T 06-07-2017 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00745 ada1b8904f405cf47e7b163c9fdfc1f9 166 SUPERFAMILY SSF54768 8 76 1.88E-25 T 06-07-2017 GTHT12_RS00745 ada1b8904f405cf47e7b163c9fdfc1f9 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 06-07-2017 IPR018192 Ribosomal protein S5, N-terminal, conserved site GTHT12_RS00745 ada1b8904f405cf47e7b163c9fdfc1f9 166 Gene3D G3DSA:3.30.160.20 10 72 6.2E-34 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain GTHT12_RS00745 ada1b8904f405cf47e7b163c9fdfc1f9 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 157 8.3E-32 T 06-07-2017 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 GTHT12_RS13500 a06b3b56a938c30e7428216b921f8c5d 750 SUPERFAMILY SSF82866 217 415 1.44E-37 T 06-07-2017 GTHT12_RS13500 a06b3b56a938c30e7428216b921f8c5d 750 SUPERFAMILY SSF82866 143 155 1.44E-37 T 06-07-2017 GTHT12_RS13500 a06b3b56a938c30e7428216b921f8c5d 750 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 34 407 4.0E-107 T 06-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 GTHT12_RS13500 a06b3b56a938c30e7428216b921f8c5d 750 PRINTS PR01755 Bacterial translocase SecF protein signature 669 684 6.1E-27 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial GTHT12_RS13500 a06b3b56a938c30e7428216b921f8c5d 750 PRINTS PR01755 Bacterial translocase SecF protein signature 634 652 6.1E-27 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial GTHT12_RS13500 a06b3b56a938c30e7428216b921f8c5d 750 PRINTS PR01755 Bacterial translocase SecF protein signature 586 600 6.1E-27 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial GTHT12_RS13500 a06b3b56a938c30e7428216b921f8c5d 750 PRINTS PR01755 Bacterial translocase SecF protein signature 476 491 6.1E-27 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial GTHT12_RS13500 a06b3b56a938c30e7428216b921f8c5d 750 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 188 400 2.4E-52 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial GTHT12_RS13500 a06b3b56a938c30e7428216b921f8c5d 750 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 525 718 1.1E-50 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial GTHT12_RS13500 a06b3b56a938c30e7428216b921f8c5d 750 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 449 732 26.496 T 06-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 GTHT12_RS13500 a06b3b56a938c30e7428216b921f8c5d 750 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 477 721 5.2E-72 T 06-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 GTHT12_RS13500 a06b3b56a938c30e7428216b921f8c5d 750 Pfam PF02355 Protein export membrane protein 242 403 2.4E-10 T 06-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial GTHT12_RS13500 a06b3b56a938c30e7428216b921f8c5d 750 Pfam PF02355 Protein export membrane protein 553 729 3.8E-65 T 06-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial GTHT12_RS13500 a06b3b56a938c30e7428216b921f8c5d 750 SUPERFAMILY SSF82866 548 732 2.35E-36 T 06-07-2017 GTHT12_RS13500 a06b3b56a938c30e7428216b921f8c5d 750 Gene3D G3DSA:1.20.1640.10 221 419 2.5E-23 T 06-07-2017 GTHT12_RS13500 a06b3b56a938c30e7428216b921f8c5d 750 Gene3D G3DSA:1.20.1640.10 540 736 3.3E-23 T 06-07-2017 GTHT12_RS13500 a06b3b56a938c30e7428216b921f8c5d 750 Pfam PF07549 SecD/SecF GG Motif 471 497 3.4E-9 T 06-07-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site GTHT12_RS13500 a06b3b56a938c30e7428216b921f8c5d 750 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 421 32.137 T 06-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 GTHT12_RS12535 cc27d091adf00ed0df6fe038d183c827 284 SUPERFAMILY SSF51735 122 278 8.72E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS12535 cc27d091adf00ed0df6fe038d183c827 284 SUPERFAMILY SSF53223 1 121 1.73E-43 T 06-07-2017 GTHT12_RS12535 cc27d091adf00ed0df6fe038d183c827 284 Gene3D G3DSA:3.40.50.720 139 263 4.0E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS12535 cc27d091adf00ed0df6fe038d183c827 284 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 40.333 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 GTHT12_RS12535 cc27d091adf00ed0df6fe038d183c827 284 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 06-07-2017 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 GTHT12_RS12535 cc27d091adf00ed0df6fe038d183c827 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 1.3E-89 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 GTHT12_RS12535 cc27d091adf00ed0df6fe038d183c827 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 1.3E-89 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 GTHT12_RS12535 cc27d091adf00ed0df6fe038d183c827 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 1.3E-89 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 GTHT12_RS12535 cc27d091adf00ed0df6fe038d183c827 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 1.3E-89 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 GTHT12_RS12535 cc27d091adf00ed0df6fe038d183c827 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 1.3E-89 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 GTHT12_RS12535 cc27d091adf00ed0df6fe038d183c827 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 1.3E-89 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 GTHT12_RS12535 cc27d091adf00ed0df6fe038d183c827 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 1.3E-89 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 GTHT12_RS12535 cc27d091adf00ed0df6fe038d183c827 284 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 06-07-2017 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 GTHT12_RS12535 cc27d091adf00ed0df6fe038d183c827 284 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 280 1.7E-71 T 06-07-2017 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 GTHT12_RS12535 cc27d091adf00ed0df6fe038d183c827 284 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 2.3E-44 T 06-07-2017 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 GTHT12_RS12535 cc27d091adf00ed0df6fe038d183c827 284 Gene3D G3DSA:3.40.192.10 7 138 4.5E-55 T 06-07-2017 GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 Pfam PF00158 Sigma-54 interaction domain 368 535 6.9E-69 T 06-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 Gene3D G3DSA:1.10.8.60 543 614 6.4E-25 T 06-07-2017 GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 Gene3D G3DSA:3.30.450.20 233 340 3.5E-15 T 06-07-2017 GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 Gene3D G3DSA:1.10.10.60 623 682 6.1E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 Pfam PF02954 Bacterial regulatory protein, Fis family 641 679 2.8E-12 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 115 227 5.2E-9 T 06-07-2017 IPR000014 PAS domain GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 233 349 8.3E-18 T 06-07-2017 IPR000014 PAS domain GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 SUPERFAMILY SSF51735 1 110 1.29E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 645 662 1.7E-10 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 662 682 1.7E-10 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 455 470 - T 06-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 Gene3D G3DSA:3.40.50.720 2 118 3.2E-10 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 SUPERFAMILY SSF52540 367 612 7.87E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 Gene3D G3DSA:3.40.50.300 365 541 4.7E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 Gene3D G3DSA:3.30.450.20 120 232 7.2E-13 T 06-07-2017 GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 SMART SM00382 388 532 9.7E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 SUPERFAMILY SSF55785 105 215 7.5E-14 T 06-07-2017 IPR000014 PAS domain GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 392 405 - T 06-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 SUPERFAMILY SSF55785 217 336 6.81E-16 T 06-07-2017 IPR000014 PAS domain GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 582 591 - T 06-07-2017 IPR025944 Sigma-54 interaction domain, conserved site GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 SMART SM00091 236 301 1.6E-6 T 06-07-2017 IPR000014 PAS domain GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 SMART SM00091 117 183 6.2E-7 T 06-07-2017 IPR000014 PAS domain GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 Pfam PF00989 PAS fold 118 218 1.9E-8 T 06-07-2017 IPR013767 PAS fold GO:0006355 GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 Pfam PF00989 PAS fold 237 339 3.7E-14 T 06-07-2017 IPR013767 PAS fold GO:0006355 GTHT12_RS12455 d92d1834ebe6251c3a724d56a99dc39b 687 SUPERFAMILY SSF46689 582 682 5.38E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS16470 4e9a65a0a23590038521716c198444e6 535 ProSitePatterns PS00216 Sugar transport proteins signature 1. 71 87 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 GTHT12_RS16470 4e9a65a0a23590038521716c198444e6 535 PRINTS PR01036 Tetracycline resistance protein TetB signature 21 45 7.4E-13 T 06-07-2017 GTHT12_RS16470 4e9a65a0a23590038521716c198444e6 535 PRINTS PR01036 Tetracycline resistance protein TetB signature 404 423 7.4E-13 T 06-07-2017 GTHT12_RS16470 4e9a65a0a23590038521716c198444e6 535 PRINTS PR01036 Tetracycline resistance protein TetB signature 111 131 7.4E-13 T 06-07-2017 GTHT12_RS16470 4e9a65a0a23590038521716c198444e6 535 PRINTS PR01036 Tetracycline resistance protein TetB signature 362 382 7.4E-13 T 06-07-2017 GTHT12_RS16470 4e9a65a0a23590038521716c198444e6 535 PRINTS PR01036 Tetracycline resistance protein TetB signature 306 330 7.4E-13 T 06-07-2017 GTHT12_RS16470 4e9a65a0a23590038521716c198444e6 535 PRINTS PR01036 Tetracycline resistance protein TetB signature 141 165 7.4E-13 T 06-07-2017 GTHT12_RS16470 4e9a65a0a23590038521716c198444e6 535 PRINTS PR01036 Tetracycline resistance protein TetB signature 342 362 7.4E-13 T 06-07-2017 GTHT12_RS16470 4e9a65a0a23590038521716c198444e6 535 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 18 484 8.2E-83 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 GTHT12_RS16470 4e9a65a0a23590038521716c198444e6 535 Gene3D G3DSA:1.20.1250.20 258 424 7.5E-32 T 06-07-2017 GTHT12_RS16470 4e9a65a0a23590038521716c198444e6 535 Gene3D G3DSA:1.20.1250.20 494 526 7.5E-32 T 06-07-2017 GTHT12_RS16470 4e9a65a0a23590038521716c198444e6 535 Gene3D G3DSA:1.20.1250.20 13 190 6.2E-30 T 06-07-2017 GTHT12_RS16470 4e9a65a0a23590038521716c198444e6 535 Pfam PF07690 Major Facilitator Superfamily 22 414 1.0E-52 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS16470 4e9a65a0a23590038521716c198444e6 535 SUPERFAMILY SSF103473 14 206 1.13E-75 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS16470 4e9a65a0a23590038521716c198444e6 535 SUPERFAMILY SSF103473 253 423 1.13E-75 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS16470 4e9a65a0a23590038521716c198444e6 535 SUPERFAMILY SSF103473 493 526 1.13E-75 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS04350 db69e619d7d69315c3f1e40093cc6d21 502 Pfam PF13396 Phospholipase_D-nuclease N-terminal 42 81 1.9E-9 T 06-07-2017 IPR027379 Cardiolipin synthase N-terminal GTHT12_RS04350 db69e619d7d69315c3f1e40093cc6d21 502 Gene3D G3DSA:3.30.870.10 134 330 7.4E-51 T 06-07-2017 GTHT12_RS04350 db69e619d7d69315c3f1e40093cc6d21 502 SUPERFAMILY SSF56024 114 333 8.75E-54 T 06-07-2017 GTHT12_RS04350 db69e619d7d69315c3f1e40093cc6d21 502 Gene3D G3DSA:3.30.870.10 331 477 1.8E-37 T 06-07-2017 GTHT12_RS04350 db69e619d7d69315c3f1e40093cc6d21 502 SMART SM00155 415 442 1.1E-7 T 06-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 GTHT12_RS04350 db69e619d7d69315c3f1e40093cc6d21 502 SMART SM00155 237 264 1.1E-4 T 06-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 GTHT12_RS04350 db69e619d7d69315c3f1e40093cc6d21 502 SUPERFAMILY SSF56024 289 488 7.18E-51 T 06-07-2017 GTHT12_RS04350 db69e619d7d69315c3f1e40093cc6d21 502 Hamap MF_01916 Cardiolipin synthase. 34 502 41.732 T 06-07-2017 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 GTHT12_RS04350 db69e619d7d69315c3f1e40093cc6d21 502 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 31 502 4.6E-182 T 06-07-2017 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 GTHT12_RS04350 db69e619d7d69315c3f1e40093cc6d21 502 Pfam PF13091 PLD-like domain 155 297 2.4E-12 T 06-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 GTHT12_RS04350 db69e619d7d69315c3f1e40093cc6d21 502 Pfam PF13091 PLD-like domain 344 468 2.8E-26 T 06-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 GTHT12_RS08835 63fc982b9b7f7119122148cb500c7055 437 SMART SM00267 257 428 2.8E-65 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS08835 63fc982b9b7f7119122148cb500c7055 437 Pfam PF13188 PAS domain 150 203 5.9E-8 T 06-07-2017 IPR000014 PAS domain GTHT12_RS08835 63fc982b9b7f7119122148cb500c7055 437 SUPERFAMILY SSF55785 137 255 1.55E-18 T 06-07-2017 IPR000014 PAS domain GTHT12_RS08835 63fc982b9b7f7119122148cb500c7055 437 Pfam PF08448 PAS fold 23 132 1.7E-9 T 06-07-2017 IPR013656 PAS fold-4 GTHT12_RS08835 63fc982b9b7f7119122148cb500c7055 437 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 21 136 4.7E-6 T 06-07-2017 IPR000014 PAS domain GTHT12_RS08835 63fc982b9b7f7119122148cb500c7055 437 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 146 264 7.7E-15 T 06-07-2017 IPR000014 PAS domain GTHT12_RS08835 63fc982b9b7f7119122148cb500c7055 437 Gene3D G3DSA:3.30.450.20 15 131 6.1E-14 T 06-07-2017 GTHT12_RS08835 63fc982b9b7f7119122148cb500c7055 437 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 265 425 2.6E-43 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS08835 63fc982b9b7f7119122148cb500c7055 437 SUPERFAMILY SSF55785 21 131 6.58E-11 T 06-07-2017 IPR000014 PAS domain GTHT12_RS08835 63fc982b9b7f7119122148cb500c7055 437 Gene3D G3DSA:3.30.450.20 137 255 6.4E-17 T 06-07-2017 GTHT12_RS08835 63fc982b9b7f7119122148cb500c7055 437 SUPERFAMILY SSF55073 273 430 7.45E-47 T 06-07-2017 IPR029787 Nucleotide cyclase GTHT12_RS08835 63fc982b9b7f7119122148cb500c7055 437 Gene3D G3DSA:3.30.70.270 269 435 2.2E-53 T 06-07-2017 GTHT12_RS08835 63fc982b9b7f7119122148cb500c7055 437 Pfam PF00990 Diguanylate cyclase, GGDEF domain 268 422 1.8E-47 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS08835 63fc982b9b7f7119122148cb500c7055 437 SMART SM00091 150 217 2.2E-5 T 06-07-2017 IPR000014 PAS domain GTHT12_RS08835 63fc982b9b7f7119122148cb500c7055 437 SMART SM00091 17 84 89.0 T 06-07-2017 IPR000014 PAS domain GTHT12_RS01420 9ec8bb77a75f18a0b83d28a36b34784e 152 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 9 131 6.4E-40 T 06-07-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 GTHT12_RS01420 9ec8bb77a75f18a0b83d28a36b34784e 152 SUPERFAMILY SSF52540 17 123 7.62E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01420 9ec8bb77a75f18a0b83d28a36b34784e 152 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 12 133 2.1E-43 T 06-07-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 GTHT12_RS01420 9ec8bb77a75f18a0b83d28a36b34784e 152 Gene3D G3DSA:3.40.50.300 3 149 3.0E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03590 361a8f3547aac6dc745e9baa6e81d89c 288 Gene3D G3DSA:3.30.1240.10 84 192 3.2E-51 T 06-07-2017 GTHT12_RS03590 361a8f3547aac6dc745e9baa6e81d89c 288 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 241 3.1E-17 T 06-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 GTHT12_RS03590 361a8f3547aac6dc745e9baa6e81d89c 288 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 266 6.6E-42 T 06-07-2017 IPR000150 Cof protein GO:0016787 GTHT12_RS03590 361a8f3547aac6dc745e9baa6e81d89c 288 SUPERFAMILY SSF56784 3 273 9.84E-55 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS03590 361a8f3547aac6dc745e9baa6e81d89c 288 Gene3D G3DSA:3.40.50.1000 3 72 1.7E-43 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS03590 361a8f3547aac6dc745e9baa6e81d89c 288 Gene3D G3DSA:3.40.50.1000 193 276 1.7E-43 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS03590 361a8f3547aac6dc745e9baa6e81d89c 288 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 267 1.3E-50 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS13320 9fd43803a1379d7b1c7244655e971529 210 Pfam PF07423 Protein of unknown function (DUF1510) 6 206 6.6E-69 T 06-07-2017 IPR009988 Protein of unknown function DUF1510 GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 Pfam PF08264 Anticodon-binding domain of tRNA 655 767 4.2E-22 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 219 399 2.0E-72 T 06-07-2017 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 2 804 23.844 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 Pfam PF09334 tRNA synthetases class I (M) 38 170 9.2E-19 T 06-07-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 7.6E-59 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 7.6E-59 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 7.6E-59 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 7.6E-59 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 213 232 7.6E-59 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 7.6E-59 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 7.6E-59 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 Gene3D G3DSA:3.40.50.620 1 220 1.9E-170 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 Gene3D G3DSA:3.40.50.620 420 604 1.9E-170 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 804 0.0 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 SUPERFAMILY SSF47323 619 804 3.18E-43 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 SUPERFAMILY SSF50677 224 410 6.91E-59 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 Gene3D G3DSA:1.10.730.10 605 740 9.9E-44 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 SUPERFAMILY SSF52374 2 224 1.61E-152 T 06-07-2017 GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 SUPERFAMILY SSF52374 411 625 1.61E-152 T 06-07-2017 GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 Gene3D G3DSA:3.90.740.10 221 419 6.5E-63 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 412 604 7.5E-21 T 06-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS14740 84164109b7c4147ca6033ce69f182be8 805 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS14920 8525fc4ea35873f2cce132a9cffa3147 799 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 639 651 - T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 GTHT12_RS14920 8525fc4ea35873f2cce132a9cffa3147 799 Gene3D G3DSA:3.40.50.2000 465 779 5.0E-135 T 06-07-2017 GTHT12_RS14920 8525fc4ea35873f2cce132a9cffa3147 799 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 4 795 0.0 T 06-07-2017 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 GTHT12_RS14920 8525fc4ea35873f2cce132a9cffa3147 799 Pfam PF00343 Carbohydrate phosphorylase 93 795 0.0 T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 GTHT12_RS14920 8525fc4ea35873f2cce132a9cffa3147 799 Gene3D G3DSA:3.40.50.2000 4 464 4.7E-195 T 06-07-2017 GTHT12_RS14920 8525fc4ea35873f2cce132a9cffa3147 799 SUPERFAMILY SSF53756 3 796 0.0 T 06-07-2017 GTHT12_RS14920 8525fc4ea35873f2cce132a9cffa3147 799 PIRSF PIRSF000460 3 799 3.9E-240 T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 GTHT12_RS13290 fc6c61fdcfd1ff9f67b0ac74055ad4df 81 ProDom PD057834 YRHC TRANSMEMBRANE MEMBRANE 5 75 3.0E-5 T 06-07-2017 IPR025418 YrhC-like protein GTHT12_RS13290 fc6c61fdcfd1ff9f67b0ac74055ad4df 81 Pfam PF14143 YrhC-like protein 9 76 1.4E-21 T 06-07-2017 IPR025418 YrhC-like protein GTHT12_RS06575 9dce3d7658111a077a90aec0eba103e7 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 4 89 2.2E-43 T 06-07-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS06575 9dce3d7658111a077a90aec0eba103e7 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 06-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS06575 9dce3d7658111a077a90aec0eba103e7 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 23.643 T 06-07-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS06575 9dce3d7658111a077a90aec0eba103e7 89 SUPERFAMILY SSF47060 3 89 3.83E-38 T 06-07-2017 IPR009068 S15/NS1, RNA-binding GTHT12_RS06575 9dce3d7658111a077a90aec0eba103e7 89 SMART SM01387 8 88 2.9E-55 T 06-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS06575 9dce3d7658111a077a90aec0eba103e7 89 Pfam PF00312 Ribosomal protein S15 8 88 5.6E-40 T 06-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS06575 9dce3d7658111a077a90aec0eba103e7 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 3.0E-38 T 06-07-2017 GTHT12_RS06575 9dce3d7658111a077a90aec0eba103e7 89 Gene3D G3DSA:1.10.287.10 3 89 3.6E-42 T 06-07-2017 IPR009068 S15/NS1, RNA-binding GTHT12_RS17950 6577222b625d28dca1bae89a83262ba8 320 Gene3D G3DSA:2.60.120.10 233 316 1.5E-26 T 06-07-2017 IPR014710 RmlC-like jelly roll fold GTHT12_RS17950 6577222b625d28dca1bae89a83262ba8 320 SUPERFAMILY SSF51182 3 314 3.7E-107 T 06-07-2017 IPR011051 RmlC-like cupin domain GTHT12_RS17950 6577222b625d28dca1bae89a83262ba8 320 Gene3D G3DSA:2.60.120.10 2 218 1.2E-78 T 06-07-2017 IPR014710 RmlC-like jelly roll fold GTHT12_RS17950 6577222b625d28dca1bae89a83262ba8 320 Pfam PF01238 Phosphomannose isomerase type I 7 313 3.9E-48 T 06-07-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 GTHT12_RS17950 6577222b625d28dca1bae89a83262ba8 320 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 6 314 2.9E-81 T 06-07-2017 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 GTHT12_RS17950 6577222b625d28dca1bae89a83262ba8 320 PIRSF PIRSF036894 3 317 2.2E-132 T 06-07-2017 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 GTHT12_RS12115 b12c11ad1285f403ab4d5dc6ff838f19 366 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 100 1.8E-21 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 GTHT12_RS12115 b12c11ad1285f403ab4d5dc6ff838f19 366 PIRSF PIRSF006769 1 362 2.7E-140 T 06-07-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 GTHT12_RS12115 b12c11ad1285f403ab4d5dc6ff838f19 366 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 8 356 5.3E-132 T 06-07-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 GTHT12_RS12115 b12c11ad1285f403ab4d5dc6ff838f19 366 SUPERFAMILY SSF53597 146 356 2.42E-63 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 GTHT12_RS12115 b12c11ad1285f403ab4d5dc6ff838f19 366 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 51 89 - T 06-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 GTHT12_RS12115 b12c11ad1285f403ab4d5dc6ff838f19 366 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 147 359 3.8E-75 T 06-07-2017 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 GTHT12_RS12115 b12c11ad1285f403ab4d5dc6ff838f19 366 Gene3D G3DSA:3.40.140.10 3 129 8.8E-36 T 06-07-2017 GTHT12_RS12115 b12c11ad1285f403ab4d5dc6ff838f19 366 Gene3D G3DSA:3.40.430.10 130 362 8.6E-80 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 GTHT12_RS12115 b12c11ad1285f403ab4d5dc6ff838f19 366 SUPERFAMILY SSF53927 4 144 8.84E-49 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 GTHT12_RS12115 b12c11ad1285f403ab4d5dc6ff838f19 366 Pfam PF01872 RibD C-terminal domain 148 355 1.7E-58 T 06-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 GTHT12_RS06170 d91e5daaaad4327ed7b140aad396a521 198 Gene3D G3DSA:1.10.10.10 3 41 4.2E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS06170 d91e5daaaad4327ed7b140aad396a521 198 Pfam PF01575 MaoC like domain 102 166 1.4E-4 T 06-07-2017 IPR002539 MaoC-like domain GTHT12_RS06170 d91e5daaaad4327ed7b140aad396a521 198 SUPERFAMILY SSF54637 74 182 2.84E-25 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS06170 d91e5daaaad4327ed7b140aad396a521 198 Hamap MF_01814 Transcription factor FapR [fapR]. 1 187 39.597 T 06-07-2017 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 GTHT12_RS06170 d91e5daaaad4327ed7b140aad396a521 198 SUPERFAMILY SSF46785 5 51 2.5E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS06170 d91e5daaaad4327ed7b140aad396a521 198 Gene3D G3DSA:3.10.129.10 64 184 9.5E-29 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS06170 d91e5daaaad4327ed7b140aad396a521 198 PIRSF PIRSF037733 1 190 3.3E-87 T 06-07-2017 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 GTHT12_RS14455 47f8be3e703f1f19a06e146a7e8d4bf5 200 SMART SM00363 92 156 1.1E-19 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS14455 47f8be3e703f1f19a06e146a7e8d4bf5 200 Gene3D G3DSA:3.10.290.10 95 191 1.6E-36 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS14455 47f8be3e703f1f19a06e146a7e8d4bf5 200 ProSitePatterns PS00632 Ribosomal protein S4 signature. 90 114 - T 06-07-2017 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS14455 47f8be3e703f1f19a06e146a7e8d4bf5 200 Pfam PF01479 S4 domain 93 139 2.1E-21 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS14455 47f8be3e703f1f19a06e146a7e8d4bf5 200 SUPERFAMILY SSF55174 2 200 3.79E-71 T 06-07-2017 GTHT12_RS14455 47f8be3e703f1f19a06e146a7e8d4bf5 200 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 91 4.4E-29 T 06-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 GTHT12_RS14455 47f8be3e703f1f19a06e146a7e8d4bf5 200 SMART SM01390 3 91 1.9E-49 T 06-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 GTHT12_RS14455 47f8be3e703f1f19a06e146a7e8d4bf5 200 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 200 37.054 T 06-07-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 GTHT12_RS14455 47f8be3e703f1f19a06e146a7e8d4bf5 200 Gene3D G3DSA:1.10.1050.10 1 94 8.8E-41 T 06-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 GTHT12_RS14455 47f8be3e703f1f19a06e146a7e8d4bf5 200 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 200 3.4E-87 T 06-07-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 GTHT12_RS00940 9d9e03283de6c11937dc99b53e3c6d21 448 Gene3D G3DSA:3.40.120.10 175 249 3.9E-24 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS00940 9d9e03283de6c11937dc99b53e3c6d21 448 SUPERFAMILY SSF55957 357 446 3.79E-28 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS00940 9d9e03283de6c11937dc99b53e3c6d21 448 Gene3D G3DSA:3.40.120.10 3 145 6.7E-47 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS00940 9d9e03283de6c11937dc99b53e3c6d21 448 Gene3D G3DSA:3.30.310.50 370 443 3.6E-25 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS00940 9d9e03283de6c11937dc99b53e3c6d21 448 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 442 1.2E-190 T 06-07-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS00940 9d9e03283de6c11937dc99b53e3c6d21 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 5.9E-13 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS00940 9d9e03283de6c11937dc99b53e3c6d21 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 107 5.9E-13 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS00940 9d9e03283de6c11937dc99b53e3c6d21 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 5.9E-13 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS00940 9d9e03283de6c11937dc99b53e3c6d21 448 SUPERFAMILY SSF53738 257 365 1.88E-35 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS00940 9d9e03283de6c11937dc99b53e3c6d21 448 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 442 1.6E-19 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS00940 9d9e03283de6c11937dc99b53e3c6d21 448 SUPERFAMILY SSF53738 158 256 1.41E-27 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS00940 9d9e03283de6c11937dc99b53e3c6d21 448 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 253 7.0E-18 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS00940 9d9e03283de6c11937dc99b53e3c6d21 448 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 94 103 - T 06-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS00940 9d9e03283de6c11937dc99b53e3c6d21 448 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 444 46.05 T 06-07-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS00940 9d9e03283de6c11937dc99b53e3c6d21 448 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 369 1.0E-38 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS00940 9d9e03283de6c11937dc99b53e3c6d21 448 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 133 1.1E-43 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS00940 9d9e03283de6c11937dc99b53e3c6d21 448 Gene3D G3DSA:3.40.120.10 250 369 6.7E-43 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS00940 9d9e03283de6c11937dc99b53e3c6d21 448 SUPERFAMILY SSF53738 3 180 6.67E-48 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 GTHT12_RS07130 ef4f5a7627d826469d115a28571928e7 350 SUPERFAMILY SSF52540 160 328 4.62E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07130 ef4f5a7627d826469d115a28571928e7 350 Gene3D G3DSA:3.40.50.300 140 321 3.5E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07130 ef4f5a7627d826469d115a28571928e7 350 Pfam PF07728 AAA domain (dynein-related subfamily) 163 314 5.0E-8 T 06-07-2017 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 GTHT12_RS07130 ef4f5a7627d826469d115a28571928e7 350 Pfam PF12102 Domain of unknown function (DUF3578) 1 112 4.7E-32 T 06-07-2017 IPR021961 Protein of unknown function DUF3578 GTHT12_RS00180 67318f68f6b31436f5e8eac69543409d 275 Pfam PF04468 PSP1 C-terminal conserved region 61 146 8.7E-32 T 06-07-2017 IPR007557 PSP1, C-terminal GTHT12_RS05055 d24f02e1f898dc8be8943b465b6316aa 211 SMART SM01007 9 197 8.6E-44 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal GTHT12_RS05055 d24f02e1f898dc8be8943b465b6316aa 211 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 205 111.082 T 06-07-2017 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 GTHT12_RS05055 d24f02e1f898dc8be8943b465b6316aa 211 SUPERFAMILY SSF53639 6 203 3.34E-45 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal GTHT12_RS05055 d24f02e1f898dc8be8943b465b6316aa 211 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 11 200 1.5E-64 T 06-07-2017 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 GTHT12_RS05055 d24f02e1f898dc8be8943b465b6316aa 211 Gene3D G3DSA:3.40.225.10 6 204 8.2E-43 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal GTHT12_RS05055 d24f02e1f898dc8be8943b465b6316aa 211 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 197 3.9E-40 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 SUPERFAMILY SSF100920 353 509 4.05E-64 T 06-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 572 1.6E-290 T 06-07-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 SUPERFAMILY SSF53067 159 350 4.75E-69 T 06-07-2017 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 Gene3D G3DSA:3.30.420.40 288 330 2.7E-37 T 06-07-2017 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 Gene3D G3DSA:3.30.420.40 164 198 2.7E-37 T 06-07-2017 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 Gene3D G3DSA:2.60.34.10 359 500 2.3E-74 T 06-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 Gene3D G3DSA:3.90.640.10 199 284 3.1E-31 T 06-07-2017 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 165 178 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 Gene3D G3DSA:1.20.1270.10 501 572 2.2E-22 T 06-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 601 37.715 T 06-07-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 SUPERFAMILY SSF100934 476 580 5.1E-14 T 06-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 Gene3D G3DSA:3.30.30.30 39 98 3.3E-16 T 06-07-2017 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 Gene3D G3DSA:3.30.420.40 3 38 9.0E-59 T 06-07-2017 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 Gene3D G3DSA:3.30.420.40 99 163 9.0E-59 T 06-07-2017 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 306 320 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 SUPERFAMILY SSF53067 1 157 1.25E-59 T 06-07-2017 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 PRINTS PR00301 70kDa heat shock protein signature 334 354 2.1E-80 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 PRINTS PR00301 70kDa heat shock protein signature 303 319 2.1E-80 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.1E-80 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 PRINTS PR00301 70kDa heat shock protein signature 112 132 2.1E-80 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 PRINTS PR00301 70kDa heat shock protein signature 171 181 2.1E-80 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 PRINTS PR00301 70kDa heat shock protein signature 357 376 2.1E-80 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.1E-80 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 PRINTS PR00301 70kDa heat shock protein signature 53 61 2.1E-80 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 PRINTS PR00301 70kDa heat shock protein signature 438 454 2.1E-80 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GTHT12_RS13125 f23d1ebf048ece3831490deae4905def 605 Pfam PF00012 Hsp70 protein 76 572 4.4E-223 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GTHT12_RS07680 9bae43e352de92569d167d45b73d8082 398 SUPERFAMILY SSF103473 13 393 1.23E-65 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS07680 9bae43e352de92569d167d45b73d8082 398 Gene3D G3DSA:1.20.1250.20 18 202 2.3E-35 T 06-07-2017 GTHT12_RS07680 9bae43e352de92569d167d45b73d8082 398 Gene3D G3DSA:1.20.1250.20 214 394 8.5E-15 T 06-07-2017 GTHT12_RS07680 9bae43e352de92569d167d45b73d8082 398 Pfam PF07690 Major Facilitator Superfamily 19 329 1.7E-42 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS03740 0705ea2925932c3a3e08966b6a8a8434 287 Gene3D G3DSA:3.30.470.10 14 122 3.1E-31 T 06-07-2017 GTHT12_RS03740 0705ea2925932c3a3e08966b6a8a8434 287 Gene3D G3DSA:3.20.10.10 128 279 2.7E-48 T 06-07-2017 GTHT12_RS03740 0705ea2925932c3a3e08966b6a8a8434 287 SUPERFAMILY SSF56752 10 279 1.24E-76 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 GTHT12_RS03740 0705ea2925932c3a3e08966b6a8a8434 287 TIGRFAM TIGR01121 D_amino_aminoT: D-amino-acid transaminase 7 279 1.8E-99 T 06-07-2017 IPR005784 D-amino acid aminotransferase GO:0008483|GO:0030170|GO:0046416 KEGG: 00310+2.6.1.21|KEGG: 00330+2.6.1.21|KEGG: 00360+2.6.1.21|KEGG: 00472+2.6.1.21|KEGG: 00473+2.6.1.21 GTHT12_RS03740 0705ea2925932c3a3e08966b6a8a8434 287 ProSitePatterns PS00770 Aminotransferases class-IV signature. 181 210 - T 06-07-2017 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 GTHT12_RS03740 0705ea2925932c3a3e08966b6a8a8434 287 Pfam PF01063 Amino-transferase class IV 33 254 2.0E-49 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 GTHT12_RS10830 edec280e1be90e4716119af16f29d9ab 188 Hamap MF_00109 Shikimate kinase [aroK]. 11 178 24.859 T 06-07-2017 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 GTHT12_RS10830 edec280e1be90e4716119af16f29d9ab 188 SUPERFAMILY SSF52540 12 178 1.42E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10830 edec280e1be90e4716119af16f29d9ab 188 Gene3D G3DSA:3.40.50.300 11 178 3.3E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10830 edec280e1be90e4716119af16f29d9ab 188 PRINTS PR01100 Shikimate kinase family signature 66 74 4.9E-17 T 06-07-2017 GTHT12_RS10830 edec280e1be90e4716119af16f29d9ab 188 PRINTS PR01100 Shikimate kinase family signature 14 29 4.9E-17 T 06-07-2017 GTHT12_RS10830 edec280e1be90e4716119af16f29d9ab 188 PRINTS PR01100 Shikimate kinase family signature 85 94 4.9E-17 T 06-07-2017 GTHT12_RS10830 edec280e1be90e4716119af16f29d9ab 188 PRINTS PR01100 Shikimate kinase family signature 38 51 4.9E-17 T 06-07-2017 GTHT12_RS10830 edec280e1be90e4716119af16f29d9ab 188 Pfam PF01202 Shikimate kinase 20 177 1.7E-41 T 06-07-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 GTHT12_RS00700 7433bd7395674056d50c6c4ddd5f7515 66 Pfam PF00831 Ribosomal L29 protein 4 60 1.4E-27 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00700 7433bd7395674056d50c6c4ddd5f7515 66 Gene3D G3DSA:1.10.287.310 1 64 8.7E-33 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00700 7433bd7395674056d50c6c4ddd5f7515 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 19.988 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00700 7433bd7395674056d50c6c4ddd5f7515 66 SUPERFAMILY SSF46561 1 63 5.1E-25 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00700 7433bd7395674056d50c6c4ddd5f7515 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 06-07-2017 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00700 7433bd7395674056d50c6c4ddd5f7515 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 4.6E-26 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS05630 3c5b480e1f926e5d797fb377024bbc25 264 SUPERFAMILY SSF56655 5 259 2.62E-79 T 06-07-2017 GTHT12_RS05630 3c5b480e1f926e5d797fb377024bbc25 264 Gene3D G3DSA:3.40.190.80 173 259 3.4E-33 T 06-07-2017 GTHT12_RS05630 3c5b480e1f926e5d797fb377024bbc25 264 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 85 98 - T 06-07-2017 IPR020583 Inositol monophosphatase, metal-binding site GTHT12_RS05630 3c5b480e1f926e5d797fb377024bbc25 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 63 79 3.9E-38 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 GTHT12_RS05630 3c5b480e1f926e5d797fb377024bbc25 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 3.9E-38 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 GTHT12_RS05630 3c5b480e1f926e5d797fb377024bbc25 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 41 61 3.9E-38 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 GTHT12_RS05630 3c5b480e1f926e5d797fb377024bbc25 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 134 157 3.9E-38 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 GTHT12_RS05630 3c5b480e1f926e5d797fb377024bbc25 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 211 235 3.9E-38 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 GTHT12_RS05630 3c5b480e1f926e5d797fb377024bbc25 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 180 201 3.9E-38 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 GTHT12_RS05630 3c5b480e1f926e5d797fb377024bbc25 264 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 214 228 - T 06-07-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 GTHT12_RS05630 3c5b480e1f926e5d797fb377024bbc25 264 Gene3D G3DSA:3.30.540.10 4 160 1.9E-43 T 06-07-2017 GTHT12_RS05630 3c5b480e1f926e5d797fb377024bbc25 264 Pfam PF00459 Inositol monophosphatase family 5 259 3.2E-64 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 GTHT12_RS14945 f73190e206461c61c7ca3932bb409365 317 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 21 295 9.8E-98 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 GTHT12_RS14945 f73190e206461c61c7ca3932bb409365 317 SUPERFAMILY SSF161111 19 218 1.57E-61 T 06-07-2017 GTHT12_RS14945 f73190e206461c61c7ca3932bb409365 317 Gene3D G3DSA:1.20.1510.10 21 217 2.6E-64 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain GTHT12_RS14945 f73190e206461c61c7ca3932bb409365 317 Pfam PF01545 Cation efflux family 24 217 1.5E-52 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 GTHT12_RS14945 f73190e206461c61c7ca3932bb409365 317 SUPERFAMILY SSF160240 221 294 2.22E-9 T 06-07-2017 GTHT12_RS09965 524b660de7d4ffdd0d1146154cd43bad 281 Gene3D G3DSA:1.10.3720.10 8 268 3.3E-60 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS09965 524b660de7d4ffdd0d1146154cd43bad 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 273 1.1E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS09965 524b660de7d4ffdd0d1146154cd43bad 281 SUPERFAMILY SSF161098 10 281 2.35E-67 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS18630 55068724446b4c59f75ab631b1d04908 97 Gene3D G3DSA:1.10.1220.10 43 91 2.8E-8 T 06-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 GTHT12_RS18630 55068724446b4c59f75ab631b1d04908 97 SUPERFAMILY SSF47598 44 92 9.78E-7 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 GTHT12_RS05790 e5b321680891986932b894237e158048 259 SUPERFAMILY SSF52151 2 256 3.92E-57 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 GTHT12_RS05790 e5b321680891986932b894237e158048 259 Pfam PF01734 Patatin-like phospholipase 7 164 6.2E-22 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 GTHT12_RS05790 e5b321680891986932b894237e158048 259 Gene3D G3DSA:3.40.1090.10 7 167 3.4E-14 T 06-07-2017 GTHT12_RS11950 9e0b222bbeb8d35ebb122b31ebf8610a 262 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 262 37.728 T 06-07-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 GTHT12_RS11950 9e0b222bbeb8d35ebb122b31ebf8610a 262 Pfam PF02654 Cobalamin-5-phosphate synthase 11 249 5.0E-44 T 06-07-2017 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 GTHT12_RS08975 4a9a434bd65a8f128b6e87114e62e0ea 196 Pfam PF13238 AAA domain 3 124 6.1E-9 T 06-07-2017 GTHT12_RS08975 4a9a434bd65a8f128b6e87114e62e0ea 196 Gene3D G3DSA:3.40.50.300 2 167 2.9E-13 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08975 4a9a434bd65a8f128b6e87114e62e0ea 196 SUPERFAMILY SSF52540 1 168 3.01E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07325 725d4d707933a2692f49891983e2df85 573 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 356 420 6.3E-14 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GTHT12_RS07325 725d4d707933a2692f49891983e2df85 573 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 75 135 6.7E-17 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GTHT12_RS07325 725d4d707933a2692f49891983e2df85 573 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 8 573 59.609 T 06-07-2017 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GTHT12_RS07325 725d4d707933a2692f49891983e2df85 573 Gene3D G3DSA:3.90.480.10 344 423 7.0E-65 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GTHT12_RS07325 725d4d707933a2692f49891983e2df85 573 Gene3D G3DSA:3.90.480.10 72 143 7.0E-65 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GTHT12_RS07325 725d4d707933a2692f49891983e2df85 573 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 17 562 6.2E-282 T 06-07-2017 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GTHT12_RS07325 725d4d707933a2692f49891983e2df85 573 Gene3D G3DSA:3.30.413.10 434 561 3.8E-36 T 06-07-2017 GTHT12_RS07325 725d4d707933a2692f49891983e2df85 573 Gene3D G3DSA:3.30.413.10 146 341 6.3E-76 T 06-07-2017 GTHT12_RS07325 725d4d707933a2692f49891983e2df85 573 PRINTS PR00397 Sirohaem Fe-binding site signature 433 451 7.9E-8 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GTHT12_RS07325 725d4d707933a2692f49891983e2df85 573 PRINTS PR00397 Sirohaem Fe-binding site signature 481 499 7.9E-8 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GTHT12_RS07325 725d4d707933a2692f49891983e2df85 573 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 432 562 6.4E-4 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GTHT12_RS07325 725d4d707933a2692f49891983e2df85 573 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 170 332 6.0E-50 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GTHT12_RS07325 725d4d707933a2692f49891983e2df85 573 SUPERFAMILY SSF56014 146 346 7.33E-63 T 06-07-2017 GTHT12_RS07325 725d4d707933a2692f49891983e2df85 573 SUPERFAMILY SSF55124 348 424 4.58E-23 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GTHT12_RS07325 725d4d707933a2692f49891983e2df85 573 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 481 497 - T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GTHT12_RS07325 725d4d707933a2692f49891983e2df85 573 SUPERFAMILY SSF56014 431 563 1.83E-35 T 06-07-2017 GTHT12_RS07325 725d4d707933a2692f49891983e2df85 573 SUPERFAMILY SSF55124 13 145 6.54E-33 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 GTHT12_RS04325 c841880c57ae34af8985fa7c1ad54f65 311 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS04325 c841880c57ae34af8985fa7c1ad54f65 311 SMART SM00382 36 230 5.8E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS04325 c841880c57ae34af8985fa7c1ad54f65 311 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 269 5.3E-8 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 GTHT12_RS04325 c841880c57ae34af8985fa7c1ad54f65 311 SUPERFAMILY SSF52540 6 252 5.06E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS04325 c841880c57ae34af8985fa7c1ad54f65 311 Gene3D G3DSA:3.40.50.300 3 256 2.1E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS04325 c841880c57ae34af8985fa7c1ad54f65 311 Pfam PF00005 ABC transporter 28 180 6.2E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS07740 bf9554af63af011da0c6b19bdfb587da 560 Pfam PF00501 AMP-binding enzyme 29 453 2.2E-103 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GTHT12_RS07740 bf9554af63af011da0c6b19bdfb587da 560 Gene3D G3DSA:2.30.38.10 368 445 1.7E-24 T 06-07-2017 GTHT12_RS07740 bf9554af63af011da0c6b19bdfb587da 560 Gene3D G3DSA:3.30.300.30 451 553 1.5E-31 T 06-07-2017 GTHT12_RS07740 bf9554af63af011da0c6b19bdfb587da 560 ProSitePatterns PS00455 Putative AMP-binding domain signature. 205 216 - T 06-07-2017 IPR020845 AMP-binding, conserved site GTHT12_RS07740 bf9554af63af011da0c6b19bdfb587da 560 Pfam PF13193 AMP-binding enzyme C-terminal domain 463 540 2.6E-23 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain GTHT12_RS07740 bf9554af63af011da0c6b19bdfb587da 560 SUPERFAMILY SSF56801 9 551 2.75E-154 T 06-07-2017 GTHT12_RS07740 bf9554af63af011da0c6b19bdfb587da 560 Gene3D G3DSA:3.40.50.980 22 210 1.8E-38 T 06-07-2017 GTHT12_RS07740 bf9554af63af011da0c6b19bdfb587da 560 Gene3D G3DSA:3.40.50.980 211 367 1.4E-43 T 06-07-2017 GTHT12_RS15550 dd13e409a325a6cdd9872240e6eb2320 248 TIGRFAM TIGR02832 spo_yunB: sporulation protein YunB 12 234 6.7E-57 T 06-07-2017 IPR014197 Sporulation protein YunB GTHT12_RS15550 dd13e409a325a6cdd9872240e6eb2320 248 PIRSF PIRSF021383 1 247 1.7E-99 T 06-07-2017 IPR014197 Sporulation protein YunB GTHT12_RS15550 dd13e409a325a6cdd9872240e6eb2320 248 Pfam PF09560 Sporulation protein YunB (Spo_YunB) 142 231 2.3E-29 T 06-07-2017 IPR014197 Sporulation protein YunB GTHT12_RS03155 93740fd5a704ed1510f4d482aa035126 292 Pfam PF14540 Nucleotidyltransferase-like 1 118 8.4E-47 T 06-07-2017 IPR029348 Nucleotidyltransferase-like domain GTHT12_RS03155 93740fd5a704ed1510f4d482aa035126 292 Gene3D G3DSA:1.10.10.10 233 288 4.4E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS03155 93740fd5a704ed1510f4d482aa035126 292 Gene3D G3DSA:3.30.460.10 1 114 1.1E-52 T 06-07-2017 GTHT12_RS03155 93740fd5a704ed1510f4d482aa035126 292 ProDom PD128250 YGXA BH0953 1 277 1.0E-113 T 06-07-2017 GTHT12_RS03155 93740fd5a704ed1510f4d482aa035126 292 Gene3D G3DSA:1.20.120.330 116 231 2.5E-54 T 06-07-2017 GTHT12_RS13115 01758cc02353d947a442659df8fa403a 312 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 310 2.9E-108 T 06-07-2017 GTHT12_RS13115 01758cc02353d947a442659df8fa403a 312 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 305 8.3E-107 T 06-07-2017 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 GTHT12_RS13115 01758cc02353d947a442659df8fa403a 312 SUPERFAMILY SSF53335 78 310 1.22E-50 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS13115 01758cc02353d947a442659df8fa403a 312 Gene3D G3DSA:3.40.50.150 113 306 4.7E-49 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS13115 01758cc02353d947a442659df8fa403a 312 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 311 36.309 T 06-07-2017 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 GTHT12_RS13115 01758cc02353d947a442659df8fa403a 312 PIRSF PIRSF000401 1 312 7.9E-113 T 06-07-2017 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 GTHT12_RS17885 0c84f2d5080c88fba6f3290537a696c2 273 Gene3D G3DSA:3.40.190.10 119 217 4.0E-25 T 06-07-2017 GTHT12_RS17885 0c84f2d5080c88fba6f3290537a696c2 273 SUPERFAMILY SSF53850 5 262 2.02E-72 T 06-07-2017 GTHT12_RS17885 0c84f2d5080c88fba6f3290537a696c2 273 Gene3D G3DSA:3.40.190.10 223 263 6.2E-43 T 06-07-2017 GTHT12_RS17885 0c84f2d5080c88fba6f3290537a696c2 273 Gene3D G3DSA:3.40.190.10 40 118 6.2E-43 T 06-07-2017 GTHT12_RS17885 0c84f2d5080c88fba6f3290537a696c2 273 SMART SM00062 42 263 1.1E-73 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF GTHT12_RS17885 0c84f2d5080c88fba6f3290537a696c2 273 SMART SM00079 42 262 1.2E-5 T 06-07-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 GTHT12_RS17885 0c84f2d5080c88fba6f3290537a696c2 273 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 43 261 2.3E-67 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF GTHT12_RS06990 8fc50668a12952918a8a63e1bfde60d7 906 Gene3D G3DSA:3.30.499.10 22 251 1.1E-80 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS06990 8fc50668a12952918a8a63e1bfde60d7 906 Pfam PF00330 Aconitase family (aconitate hydratase) 79 571 1.6E-180 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS06990 8fc50668a12952918a8a63e1bfde60d7 906 PRINTS PR00415 Aconitase family signature 219 234 6.9E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS06990 8fc50668a12952918a8a63e1bfde60d7 906 PRINTS PR00415 Aconitase family signature 502 515 6.9E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS06990 8fc50668a12952918a8a63e1bfde60d7 906 PRINTS PR00415 Aconitase family signature 375 389 6.9E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS06990 8fc50668a12952918a8a63e1bfde60d7 906 PRINTS PR00415 Aconitase family signature 440 451 6.9E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS06990 8fc50668a12952918a8a63e1bfde60d7 906 PRINTS PR00415 Aconitase family signature 147 160 6.9E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS06990 8fc50668a12952918a8a63e1bfde60d7 906 PRINTS PR00415 Aconitase family signature 281 294 6.9E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS06990 8fc50668a12952918a8a63e1bfde60d7 906 PRINTS PR00415 Aconitase family signature 171 179 6.9E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS06990 8fc50668a12952918a8a63e1bfde60d7 906 PRINTS PR00415 Aconitase family signature 205 218 6.9E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS06990 8fc50668a12952918a8a63e1bfde60d7 906 PRINTS PR00415 Aconitase family signature 295 308 6.9E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS06990 8fc50668a12952918a8a63e1bfde60d7 906 Gene3D G3DSA:3.20.19.10 646 899 1.0E-77 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel GTHT12_RS06990 8fc50668a12952918a8a63e1bfde60d7 906 ProSitePatterns PS01244 Aconitase family signature 2. 502 515 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 GTHT12_RS06990 8fc50668a12952918a8a63e1bfde60d7 906 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 18 901 0.0 T 06-07-2017 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 GTHT12_RS06990 8fc50668a12952918a8a63e1bfde60d7 906 Gene3D G3DSA:3.40.1060.10 252 370 2.3E-36 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS06990 8fc50668a12952918a8a63e1bfde60d7 906 Pfam PF00694 Aconitase C-terminal domain 701 828 2.9E-46 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS06990 8fc50668a12952918a8a63e1bfde60d7 906 Gene3D G3DSA:3.30.499.10 428 584 1.3E-62 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS06990 8fc50668a12952918a8a63e1bfde60d7 906 Gene3D G3DSA:3.30.499.10 371 396 1.3E-62 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS06990 8fc50668a12952918a8a63e1bfde60d7 906 ProSitePatterns PS00450 Aconitase family signature 1. 436 452 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 GTHT12_RS06990 8fc50668a12952918a8a63e1bfde60d7 906 SUPERFAMILY SSF52016 640 900 1.24E-87 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel GTHT12_RS06990 8fc50668a12952918a8a63e1bfde60d7 906 SUPERFAMILY SSF53732 4 636 6.54E-231 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS10810 cabbaa07c12a041d830aaed221a66f8b 414 Pfam PF00171 Aldehyde dehydrogenase family 13 281 3.1E-11 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10810 cabbaa07c12a041d830aaed221a66f8b 414 Pfam PF00171 Aldehyde dehydrogenase family 305 375 6.1E-6 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10810 cabbaa07c12a041d830aaed221a66f8b 414 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 319 341 - T 06-07-2017 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 GTHT12_RS10810 cabbaa07c12a041d830aaed221a66f8b 414 Gene3D G3DSA:3.40.309.10 225 370 2.3E-39 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 GTHT12_RS10810 cabbaa07c12a041d830aaed221a66f8b 414 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 3 412 41.919 T 06-07-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 GTHT12_RS10810 cabbaa07c12a041d830aaed221a66f8b 414 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 12 402 1.4E-161 T 06-07-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 GTHT12_RS10810 cabbaa07c12a041d830aaed221a66f8b 414 Gene3D G3DSA:3.40.605.10 371 412 6.7E-101 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10810 cabbaa07c12a041d830aaed221a66f8b 414 Gene3D G3DSA:3.40.605.10 2 222 6.7E-101 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10810 cabbaa07c12a041d830aaed221a66f8b 414 PIRSF PIRSF000151 1 413 1.7E-177 T 06-07-2017 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 GTHT12_RS10810 cabbaa07c12a041d830aaed221a66f8b 414 SUPERFAMILY SSF53720 3 412 6.81E-114 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GTHT12_RS11710 3f4493599a33e3db1720361cde237b56 108 SMART SM00411 19 108 1.9E-53 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 GTHT12_RS11710 3f4493599a33e3db1720361cde237b56 108 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 64 83 - T 06-07-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 GTHT12_RS11710 3f4493599a33e3db1720361cde237b56 108 SUPERFAMILY SSF47729 19 108 1.16E-36 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 GTHT12_RS11710 3f4493599a33e3db1720361cde237b56 108 Pfam PF00216 Bacterial DNA-binding protein 19 108 2.0E-39 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 GTHT12_RS11710 3f4493599a33e3db1720361cde237b56 108 PRINTS PR01727 Prokaryotic integration host factor signature 92 106 6.5E-22 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 GTHT12_RS11710 3f4493599a33e3db1720361cde237b56 108 PRINTS PR01727 Prokaryotic integration host factor signature 76 89 6.5E-22 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 GTHT12_RS11710 3f4493599a33e3db1720361cde237b56 108 PRINTS PR01727 Prokaryotic integration host factor signature 58 73 6.5E-22 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 GTHT12_RS11710 3f4493599a33e3db1720361cde237b56 108 Gene3D G3DSA:4.10.520.10 19 108 2.3E-43 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 GTHT12_RS11485 0ab3c10e881465c5780a1c53c52fe6c1 235 Gene3D G3DSA:1.10.10.630 126 199 7.9E-31 T 06-07-2017 IPR006343 Replication protein, DnaD/DnaB domain GTHT12_RS11485 0ab3c10e881465c5780a1c53c52fe6c1 235 SUPERFAMILY SSF46785 15 92 5.81E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS11485 0ab3c10e881465c5780a1c53c52fe6c1 235 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 129 200 1.7E-26 T 06-07-2017 IPR006343 Replication protein, DnaD/DnaB domain GTHT12_RS11485 0ab3c10e881465c5780a1c53c52fe6c1 235 SUPERFAMILY SSF158499 130 195 1.83E-20 T 06-07-2017 IPR006343 Replication protein, DnaD/DnaB domain GTHT12_RS11485 0ab3c10e881465c5780a1c53c52fe6c1 235 Pfam PF07261 Replication initiation and membrane attachment 130 202 4.9E-28 T 06-07-2017 IPR006343 Replication protein, DnaD/DnaB domain GTHT12_RS11485 0ab3c10e881465c5780a1c53c52fe6c1 235 Gene3D G3DSA:1.10.10.10 16 92 4.6E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS10350 c099ff258052f6ffa3cfacfca4e6ebaa 334 Gene3D G3DSA:1.10.260.40 4 56 6.7E-25 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS10350 c099ff258052f6ffa3cfacfca4e6ebaa 334 Gene3D G3DSA:3.40.50.2300 57 174 5.7E-46 T 06-07-2017 GTHT12_RS10350 c099ff258052f6ffa3cfacfca4e6ebaa 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 51 9.2E-21 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS10350 c099ff258052f6ffa3cfacfca4e6ebaa 334 Pfam PF13377 Periplasmic binding protein-like domain 171 332 4.2E-34 T 06-07-2017 GTHT12_RS10350 c099ff258052f6ffa3cfacfca4e6ebaa 334 SUPERFAMILY SSF47413 2 62 3.38E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS10350 c099ff258052f6ffa3cfacfca4e6ebaa 334 SMART SM00354 3 74 2.8E-33 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS10350 c099ff258052f6ffa3cfacfca4e6ebaa 334 Gene3D G3DSA:3.40.50.2300 175 313 1.5E-36 T 06-07-2017 GTHT12_RS10350 c099ff258052f6ffa3cfacfca4e6ebaa 334 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 06-07-2017 GTHT12_RS10350 c099ff258052f6ffa3cfacfca4e6ebaa 334 SUPERFAMILY SSF53822 64 333 5.03E-69 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS08235 b00c101c8f580aecca636b743327de4a 450 Gene3D G3DSA:3.30.1490.20 129 202 1.4E-27 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GTHT12_RS08235 b00c101c8f580aecca636b743327de4a 450 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 443 7.9E-191 T 06-07-2017 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 GTHT12_RS08235 b00c101c8f580aecca636b743327de4a 450 SMART SM00878 336 441 4.7E-55 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GTHT12_RS08235 b00c101c8f580aecca636b743327de4a 450 SUPERFAMILY SSF56059 83 346 7.6E-74 T 06-07-2017 GTHT12_RS08235 b00c101c8f580aecca636b743327de4a 450 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 3.3E-82 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GTHT12_RS08235 b00c101c8f580aecca636b743327de4a 450 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 3.3E-47 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GTHT12_RS08235 b00c101c8f580aecca636b743327de4a 450 SUPERFAMILY SSF51246 331 444 1.41E-40 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GTHT12_RS08235 b00c101c8f580aecca636b743327de4a 450 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GTHT12_RS08235 b00c101c8f580aecca636b743327de4a 450 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GTHT12_RS08235 b00c101c8f580aecca636b743327de4a 450 Gene3D G3DSA:3.30.470.20 203 444 2.6E-103 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 GTHT12_RS08235 b00c101c8f580aecca636b743327de4a 450 Gene3D G3DSA:3.40.50.20 1 128 3.5E-54 T 06-07-2017 IPR016185 Pre-ATP-grasp domain GTHT12_RS08235 b00c101c8f580aecca636b743327de4a 450 SUPERFAMILY SSF52440 1 113 5.25E-50 T 06-07-2017 IPR016185 Pre-ATP-grasp domain GTHT12_RS08235 b00c101c8f580aecca636b743327de4a 450 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 1.1E-37 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GTHT12_RS01155 5b7f4880b95ba705fc132358300d9c36 329 SUPERFAMILY SSF81345 2 328 4.05E-77 T 06-07-2017 IPR029022 ABC transporter, BtuC-like GTHT12_RS01155 5b7f4880b95ba705fc132358300d9c36 329 Pfam PF01032 FecCD transport family 16 328 1.7E-88 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 GTHT12_RS01155 5b7f4880b95ba705fc132358300d9c36 329 Gene3D G3DSA:1.10.3470.10 2 329 5.6E-94 T 06-07-2017 IPR029022 ABC transporter, BtuC-like GTHT12_RS04815 35d7819ecff65dd1fab385e7290aa96a 354 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 240 348 1.3E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS04815 35d7819ecff65dd1fab385e7290aa96a 354 PRINTS PR00344 Bacterial sensor protein C-terminal signature 294 304 6.6E-21 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS04815 35d7819ecff65dd1fab385e7290aa96a 354 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 329 6.6E-21 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS04815 35d7819ecff65dd1fab385e7290aa96a 354 PRINTS PR00344 Bacterial sensor protein C-terminal signature 276 290 6.6E-21 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS04815 35d7819ecff65dd1fab385e7290aa96a 354 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 348 6.6E-21 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS04815 35d7819ecff65dd1fab385e7290aa96a 354 SUPERFAMILY SSF47384 112 195 1.63E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS04815 35d7819ecff65dd1fab385e7290aa96a 354 Gene3D G3DSA:1.10.287.130 119 179 2.1E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS04815 35d7819ecff65dd1fab385e7290aa96a 354 Gene3D G3DSA:3.30.565.10 180 350 3.9E-52 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS04815 35d7819ecff65dd1fab385e7290aa96a 354 SMART SM00388 129 195 2.4E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS04815 35d7819ecff65dd1fab385e7290aa96a 354 Pfam PF00512 His Kinase A (phospho-acceptor) domain 129 194 2.8E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS04815 35d7819ecff65dd1fab385e7290aa96a 354 SUPERFAMILY SSF55874 184 349 2.23E-48 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS04815 35d7819ecff65dd1fab385e7290aa96a 354 SMART SM00387 239 351 7.0E-45 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS14665 25bd4b8aa7ef6ffd0c8020182439ee69 216 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 212 30.862 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 GTHT12_RS14665 25bd4b8aa7ef6ffd0c8020182439ee69 216 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 28 209 1.9E-56 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 GTHT12_RS14665 25bd4b8aa7ef6ffd0c8020182439ee69 216 Pfam PF02390 Putative methyltransferase 38 207 1.9E-47 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 GTHT12_RS14665 25bd4b8aa7ef6ffd0c8020182439ee69 216 SUPERFAMILY SSF53335 26 210 7.81E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS14665 25bd4b8aa7ef6ffd0c8020182439ee69 216 Gene3D G3DSA:3.40.50.150 43 182 1.9E-10 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS15850 6c527c767d123e324122eb035a87a37b 155 TIGRFAM TIGR00086 smpB: SsrA-binding protein 8 149 2.5E-62 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 GTHT12_RS15850 6c527c767d123e324122eb035a87a37b 155 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 06-07-2017 IPR020081 SsrA-binding protein, conserved site GTHT12_RS15850 6c527c767d123e324122eb035a87a37b 155 Pfam PF01668 SmpB protein 8 72 1.2E-34 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 GTHT12_RS15850 6c527c767d123e324122eb035a87a37b 155 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 9 132 1.0E-66 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 GTHT12_RS15850 6c527c767d123e324122eb035a87a37b 155 Gene3D G3DSA:2.40.280.10 7 127 1.4E-57 T 06-07-2017 IPR023620 Small protein B GTHT12_RS15850 6c527c767d123e324122eb035a87a37b 155 SUPERFAMILY SSF74982 4 132 1.83E-57 T 06-07-2017 IPR023620 Small protein B GTHT12_RS15850 6c527c767d123e324122eb035a87a37b 155 Hamap MF_00023 SsrA-binding protein [smpB]. 1 155 82.162 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 GTHT12_RS07080 04103f71b15875846593046dd3ff4004 424 Hamap MF_00372 Imidazolonepropionase [hutI]. 3 416 44.16 T 06-07-2017 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 GTHT12_RS07080 04103f71b15875846593046dd3ff4004 424 SUPERFAMILY SSF51556 78 377 1.77E-89 T 06-07-2017 IPR032466 Metal-dependent hydrolase GTHT12_RS07080 04103f71b15875846593046dd3ff4004 424 TIGRFAM TIGR01224 hutI: imidazolonepropionase 34 415 7.3E-150 T 06-07-2017 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 GTHT12_RS07080 04103f71b15875846593046dd3ff4004 424 SUPERFAMILY SSF51338 32 79 6.27E-20 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS07080 04103f71b15875846593046dd3ff4004 424 SUPERFAMILY SSF51338 376 418 6.27E-20 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS07080 04103f71b15875846593046dd3ff4004 424 Gene3D G3DSA:2.30.40.10 34 83 1.2E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS07080 04103f71b15875846593046dd3ff4004 424 Pfam PF01979 Amidohydrolase family 75 416 1.4E-23 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 GTHT12_RS07080 04103f71b15875846593046dd3ff4004 424 Gene3D G3DSA:3.20.20.140 84 361 3.1E-50 T 06-07-2017 GTHT12_RS07080 04103f71b15875846593046dd3ff4004 424 Gene3D G3DSA:2.30.40.10 362 422 5.1E-10 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS09035 730f06ff658aab2bbd10a230ff082c71 353 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 9 338 1.3E-141 T 06-07-2017 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 GTHT12_RS09035 730f06ff658aab2bbd10a230ff082c71 353 Pfam PF01758 Sodium Bile acid symporter family 54 250 5.0E-67 T 06-07-2017 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 GTHT12_RS09035 730f06ff658aab2bbd10a230ff082c71 353 PIRSF PIRSF005508 1 352 3.2E-141 T 06-07-2017 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 GTHT12_RS14535 ffc33d66d1fbc0bc9e46ec55e1f4cd0e 252 Pfam PF01695 IstB-like ATP binding protein 58 232 5.6E-60 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 GTHT12_RS14535 ffc33d66d1fbc0bc9e46ec55e1f4cd0e 252 SMART SM00382 100 233 1.2E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS14535 ffc33d66d1fbc0bc9e46ec55e1f4cd0e 252 Gene3D G3DSA:3.40.50.300 72 231 3.2E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS14535 ffc33d66d1fbc0bc9e46ec55e1f4cd0e 252 SUPERFAMILY SSF52540 68 229 1.61E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS14535 ffc33d66d1fbc0bc9e46ec55e1f4cd0e 252 PIRSF PIRSF003073 1 252 8.6E-77 T 06-07-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein GTHT12_RS14545 c1bf6a838854645c2ac4782d17d702f7 178 Pfam PF00872 Transposase, Mutator family 1 155 4.0E-36 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS14545 c1bf6a838854645c2ac4782d17d702f7 178 ProSitePatterns PS01007 Transposases, Mutator family, signature. 10 34 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS04385 6064aaa46f7f8c1b9bce8187f7828370 195 SUPERFAMILY SSF55154 5 189 2.78E-30 T 06-07-2017 IPR033469 CYTH-like domain Reactome: R-HSA-196819 GTHT12_RS04385 6064aaa46f7f8c1b9bce8187f7828370 195 Gene3D G3DSA:2.40.320.10 5 177 5.0E-24 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 GTHT12_RS04385 6064aaa46f7f8c1b9bce8187f7828370 195 PIRSF PIRSF012526 1 193 6.4E-56 T 06-07-2017 IPR009195 Uncharacterised protein family YjbK GTHT12_RS04385 6064aaa46f7f8c1b9bce8187f7828370 195 Pfam PF01928 CYTH domain 6 186 4.4E-29 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 GTHT12_RS04385 6064aaa46f7f8c1b9bce8187f7828370 195 SMART SM01118 4 192 3.8E-23 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 GTHT12_RS14840 3fcb6f475732c1209c6be5018ef812c3 158 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 5 152 2.3E-52 T 06-07-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 GTHT12_RS14840 3fcb6f475732c1209c6be5018ef812c3 158 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 9 147 3.0E-76 T 06-07-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 GTHT12_RS14840 3fcb6f475732c1209c6be5018ef812c3 158 SUPERFAMILY SSF63411 5 153 4.03E-60 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 GTHT12_RS14840 3fcb6f475732c1209c6be5018ef812c3 158 Gene3D G3DSA:3.30.1360.80 5 152 8.8E-59 T 06-07-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 GTHT12_RS14840 3fcb6f475732c1209c6be5018ef812c3 158 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 2 158 33.676 T 06-07-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 GTHT12_RS14840 3fcb6f475732c1209c6be5018ef812c3 158 PIRSF PIRSF006160 2 158 5.6E-64 T 06-07-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 GTHT12_RS14840 3fcb6f475732c1209c6be5018ef812c3 158 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 50 68 3.4E-40 T 06-07-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 GTHT12_RS14840 3fcb6f475732c1209c6be5018ef812c3 158 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 6 24 3.4E-40 T 06-07-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 GTHT12_RS14840 3fcb6f475732c1209c6be5018ef812c3 158 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 29 47 3.4E-40 T 06-07-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 GTHT12_RS14840 3fcb6f475732c1209c6be5018ef812c3 158 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 79 97 3.4E-40 T 06-07-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 GTHT12_RS14840 3fcb6f475732c1209c6be5018ef812c3 158 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 120 139 3.4E-40 T 06-07-2017 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 GTHT12_RS09330 9a0afd487c5d273d1c3137ddc5b25167 161 PIRSF PIRSF000194 1 161 1.8E-61 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 GTHT12_RS09330 9a0afd487c5d273d1c3137ddc5b25167 161 PRINTS PR00070 Dihydrofolate reductase signature 92 106 6.3E-16 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 GTHT12_RS09330 9a0afd487c5d273d1c3137ddc5b25167 161 PRINTS PR00070 Dihydrofolate reductase signature 40 51 6.3E-16 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 GTHT12_RS09330 9a0afd487c5d273d1c3137ddc5b25167 161 PRINTS PR00070 Dihydrofolate reductase signature 13 23 6.3E-16 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 GTHT12_RS09330 9a0afd487c5d273d1c3137ddc5b25167 161 PRINTS PR00070 Dihydrofolate reductase signature 27 35 6.3E-16 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 GTHT12_RS09330 9a0afd487c5d273d1c3137ddc5b25167 161 Pfam PF00186 Dihydrofolate reductase 1 160 6.5E-65 T 06-07-2017 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 GTHT12_RS09330 9a0afd487c5d273d1c3137ddc5b25167 161 SUPERFAMILY SSF53597 1 161 3.14E-60 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 GTHT12_RS09330 9a0afd487c5d273d1c3137ddc5b25167 161 Gene3D G3DSA:3.40.430.10 1 161 2.5E-63 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 GTHT12_RS09330 9a0afd487c5d273d1c3137ddc5b25167 161 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 13 35 - T 06-07-2017 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-113510|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-69205 GTHT12_RS10320 132d8c914c51c114747941dcec9e9b7e 216 SUPERFAMILY SSF102198 4 213 1.09E-58 T 06-07-2017 GTHT12_RS10320 132d8c914c51c114747941dcec9e9b7e 216 Pfam PF04199 Putative cyclase 7 157 5.1E-31 T 06-07-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 GTHT12_RS10320 132d8c914c51c114747941dcec9e9b7e 216 Gene3D G3DSA:3.50.30.50 4 213 7.2E-63 T 06-07-2017 GTHT12_RS11150 434ac72e2216d37c484b3e5f7449af05 147 SUPERFAMILY SSF54637 3 145 5.38E-43 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS11150 434ac72e2216d37c484b3e5f7449af05 147 Gene3D G3DSA:3.10.129.10 3 145 5.9E-48 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS11150 434ac72e2216d37c484b3e5f7449af05 147 Pfam PF01575 MaoC like domain 16 114 2.3E-32 T 06-07-2017 IPR002539 MaoC-like domain GTHT12_RS13040 131ac0142eb92f70594ecbd8cb5c4ec7 302 Hamap MF_00367 GTPase Era [era]. 6 297 39.509 T 06-07-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 GTHT12_RS13040 131ac0142eb92f70594ecbd8cb5c4ec7 302 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 102 3.0E-5 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS13040 131ac0142eb92f70594ecbd8cb5c4ec7 302 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 11 31 3.0E-5 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS13040 131ac0142eb92f70594ecbd8cb5c4ec7 302 Gene3D G3DSA:3.30.300.20 192 293 2.3E-40 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta GTHT12_RS13040 131ac0142eb92f70594ecbd8cb5c4ec7 302 SUPERFAMILY SSF54814 181 298 8.5E-42 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 GTHT12_RS13040 131ac0142eb92f70594ecbd8cb5c4ec7 302 SUPERFAMILY SSF52540 11 206 2.19E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13040 131ac0142eb92f70594ecbd8cb5c4ec7 302 Pfam PF07650 KH domain 208 286 2.1E-21 T 06-07-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS13040 131ac0142eb92f70594ecbd8cb5c4ec7 302 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 168 1.3E-28 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 GTHT12_RS13040 131ac0142eb92f70594ecbd8cb5c4ec7 302 Gene3D G3DSA:3.40.50.300 9 191 2.8E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13040 131ac0142eb92f70594ecbd8cb5c4ec7 302 Pfam PF01926 50S ribosome-binding GTPase 11 125 4.8E-25 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS13040 131ac0142eb92f70594ecbd8cb5c4ec7 302 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 280 7.3E-111 T 06-07-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 GTHT12_RS01795 4e3a3e3d3f04943881717bcd08e0454a 300 SUPERFAMILY SSF53850 30 298 3.08E-78 T 06-07-2017 GTHT12_RS01795 4e3a3e3d3f04943881717bcd08e0454a 300 Gene3D G3DSA:3.40.190.120 141 237 4.2E-40 T 06-07-2017 GTHT12_RS01795 4e3a3e3d3f04943881717bcd08e0454a 300 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 30 294 4.4E-69 T 06-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 GTHT12_RS01795 4e3a3e3d3f04943881717bcd08e0454a 300 Gene3D G3DSA:3.40.190.10 26 140 3.3E-39 T 06-07-2017 GTHT12_RS11390 46bab5d0d5d6de9718830d82d0182dd4 328 Gene3D G3DSA:3.90.25.10 252 326 7.2E-48 T 06-07-2017 GTHT12_RS11390 46bab5d0d5d6de9718830d82d0182dd4 328 Gene3D G3DSA:3.90.25.10 171 220 7.2E-48 T 06-07-2017 GTHT12_RS11390 46bab5d0d5d6de9718830d82d0182dd4 328 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 250 1.7E-65 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 GTHT12_RS11390 46bab5d0d5d6de9718830d82d0182dd4 328 SUPERFAMILY SSF51735 2 325 2.19E-102 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS11390 46bab5d0d5d6de9718830d82d0182dd4 328 Gene3D G3DSA:3.40.50.720 2 170 2.3E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS11390 46bab5d0d5d6de9718830d82d0182dd4 328 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 1 324 2.2E-131 T 06-07-2017 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 GTHT12_RS02200 ec10890f91c49ee0e0e4c6a972c9ae05 228 SMART SM00382 32 218 2.5E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS02200 ec10890f91c49ee0e0e4c6a972c9ae05 228 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS02200 ec10890f91c49ee0e0e4c6a972c9ae05 228 SUPERFAMILY SSF52540 3 223 5.59E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS02200 ec10890f91c49ee0e0e4c6a972c9ae05 228 Gene3D G3DSA:3.40.50.300 2 222 3.9E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS02200 ec10890f91c49ee0e0e4c6a972c9ae05 228 Pfam PF00005 ABC transporter 23 169 1.7E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS18495 6d1ca79acf1a393c1f475e0b35d9f4f2 262 Pfam PF01061 ABC-2 type transporter 17 213 7.5E-17 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 GTHT12_RS18495 6d1ca79acf1a393c1f475e0b35d9f4f2 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 136 160 2.9E-8 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 GTHT12_RS18495 6d1ca79acf1a393c1f475e0b35d9f4f2 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 28 49 2.9E-8 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 GTHT12_RS18495 6d1ca79acf1a393c1f475e0b35d9f4f2 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 193 212 2.9E-8 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 GTHT12_RS18495 6d1ca79acf1a393c1f475e0b35d9f4f2 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 173 192 2.9E-8 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 GTHT12_RS18495 6d1ca79acf1a393c1f475e0b35d9f4f2 262 PIRSF PIRSF006648 2 252 3.7E-16 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 GTHT12_RS07045 267ad4c85856c3617ff6c7ff65391746 497 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 494 1.1E-229 T 06-07-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 GTHT12_RS07045 267ad4c85856c3617ff6c7ff65391746 497 PIRSF PIRSF000538 3 496 8.6E-181 T 06-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 GTHT12_RS07045 267ad4c85856c3617ff6c7ff65391746 497 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 252 1.8E-89 T 06-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 GTHT12_RS07045 267ad4c85856c3617ff6c7ff65391746 497 SUPERFAMILY SSF53067 255 493 3.45E-86 T 06-07-2017 GTHT12_RS07045 267ad4c85856c3617ff6c7ff65391746 497 Gene3D G3DSA:3.30.420.40 1 253 1.5E-106 T 06-07-2017 GTHT12_RS07045 267ad4c85856c3617ff6c7ff65391746 497 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 261 450 5.8E-65 T 06-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 GTHT12_RS07045 267ad4c85856c3617ff6c7ff65391746 497 Gene3D G3DSA:3.30.420.40 254 494 1.6E-104 T 06-07-2017 GTHT12_RS07045 267ad4c85856c3617ff6c7ff65391746 497 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 GTHT12_RS07045 267ad4c85856c3617ff6c7ff65391746 497 Hamap MF_00186 Glycerol kinase [glpK]. 3 497 60.428 T 06-07-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 GTHT12_RS07045 267ad4c85856c3617ff6c7ff65391746 497 SUPERFAMILY SSF53067 5 255 7.61E-98 T 06-07-2017 GTHT12_RS07045 267ad4c85856c3617ff6c7ff65391746 497 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 362 382 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 SUPERFAMILY SSF52440 550 668 4.03E-47 T 06-07-2017 IPR016185 Pre-ATP-grasp domain GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 SMART SM01096 420 540 1.2E-69 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 Pfam PF02142 MGS-like domain 950 1036 4.4E-22 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 Gene3D G3DSA:3.40.50.1380 931 1053 4.4E-40 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 9.1E-42 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 SMART SM00851 949 1036 2.7E-33 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 2.3E-82 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 666 867 9.5E-40 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1057 13.317 T 06-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 Gene3D G3DSA:1.10.1030.10 399 531 1.4E-52 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 830 837 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 SUPERFAMILY SSF52440 1 127 1.87E-50 T 06-07-2017 IPR016185 Pre-ATP-grasp domain GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 SUPERFAMILY SSF52335 929 1051 3.66E-34 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 SMART SM01209 672 836 0.0015 T 06-07-2017 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 Gene3D G3DSA:3.40.50.20 4 108 7.8E-44 T 06-07-2017 IPR016185 Pre-ATP-grasp domain GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 Gene3D G3DSA:3.30.470.20 739 927 3.1E-71 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 Gene3D G3DSA:3.30.470.20 201 398 1.3E-76 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.5E-64 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 1.5E-64 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 1.5E-64 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.5E-64 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.5E-64 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.5E-64 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.5E-64 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 SUPERFAMILY SSF56059 128 399 6.01E-112 T 06-07-2017 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1063 13.728 T 06-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 SUPERFAMILY SSF48108 395 546 3.92E-51 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 Gene3D G3DSA:3.40.50.20 532 655 2.9E-58 T 06-07-2017 IPR016185 Pre-ATP-grasp domain GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 SUPERFAMILY SSF56059 666 927 1.94E-103 T 06-07-2017 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1047 0.0 T 06-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 702 716 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 Gene3D G3DSA:3.30.1490.20 142 200 4.9E-25 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GTHT12_RS06010 1e5e6d18d54853a8f0df4316f318cf85 1065 Gene3D G3DSA:3.30.1490.20 679 738 1.5E-26 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GTHT12_RS12600 2df5451da70fdebe7c55d85040532101 93 ProDom PD064940 YQHV TRANSMEMBRANE MEMBRANE BH2798 12 76 4.0E-18 T 06-07-2017 IPR020390 Uncharacterised protein family YqhV GTHT12_RS12600 2df5451da70fdebe7c55d85040532101 93 Pfam PF10942 Protein of unknown function (DUF2619) 19 87 7.1E-30 T 06-07-2017 IPR020390 Uncharacterised protein family YqhV GTHT12_RS16080 cf48b5aace1fc6319e618d9dee43a719 235 SUPERFAMILY SSF51182 1 233 5.64E-68 T 06-07-2017 IPR011051 RmlC-like cupin domain GTHT12_RS16080 cf48b5aace1fc6319e618d9dee43a719 235 Pfam PF05726 Pirin C-terminal cupin domain 170 231 1.6E-4 T 06-07-2017 IPR008778 Pirin, C-terminal domain GTHT12_RS16080 cf48b5aace1fc6319e618d9dee43a719 235 Pfam PF02678 Pirin 12 118 2.0E-32 T 06-07-2017 IPR003829 Pirin, N-terminal domain GTHT12_RS16080 cf48b5aace1fc6319e618d9dee43a719 235 PIRSF PIRSF006232 1 232 1.9E-51 T 06-07-2017 IPR012093 Pirin GTHT12_RS16080 cf48b5aace1fc6319e618d9dee43a719 235 Gene3D G3DSA:2.60.120.10 4 233 9.4E-66 T 06-07-2017 IPR014710 RmlC-like jelly roll fold GTHT12_RS04565 111c1d4c207e39b7cc5e24d0fe1e2fc2 173 SUPERFAMILY SSF55144 1 169 8.37E-31 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase GTHT12_RS04565 111c1d4c207e39b7cc5e24d0fe1e2fc2 173 Pfam PF13563 2'-5' RNA ligase superfamily 15 152 9.9E-26 T 06-07-2017 GTHT12_RS04565 111c1d4c207e39b7cc5e24d0fe1e2fc2 173 Hamap MF_01444 Putative phosphoesterase . 1 168 39.921 T 06-07-2017 IPR022932 Putative phosphoesterase YjcG GTHT12_RS04565 111c1d4c207e39b7cc5e24d0fe1e2fc2 173 Gene3D G3DSA:3.90.1140.10 1 163 2.3E-18 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase GTHT12_RS15990 7a7d21238e630f744b676f1301c6528e 195 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 157 169 - T 06-07-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 GTHT12_RS15990 7a7d21238e630f744b676f1301c6528e 195 Gene3D G3DSA:3.30.230.40 91 195 7.9E-32 T 06-07-2017 GTHT12_RS15990 7a7d21238e630f744b676f1301c6528e 195 SUPERFAMILY SSF54211 3 87 8.98E-33 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS15990 7a7d21238e630f744b676f1301c6528e 195 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 175 9.4E-65 T 06-07-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 GTHT12_RS15990 7a7d21238e630f744b676f1301c6528e 195 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 195 42.48 T 06-07-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 GTHT12_RS15990 7a7d21238e630f744b676f1301c6528e 195 Gene3D G3DSA:3.30.230.40 3 90 1.7E-37 T 06-07-2017 GTHT12_RS15990 7a7d21238e630f744b676f1301c6528e 195 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 06-07-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 GTHT12_RS15990 7a7d21238e630f744b676f1301c6528e 195 SUPERFAMILY SSF54211 88 179 1.26E-34 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS06585 885f070bf634252e07fce24a64f4bd03 327 TIGRFAM TIGR02873 spore_ylxY: probable sporulation protein, polysaccharide deacetylase family 46 313 3.1E-137 T 06-07-2017 IPR014228 Sporulation protein, polysaccharide deacetylase, YlxY GTHT12_RS06585 885f070bf634252e07fce24a64f4bd03 327 Gene3D G3DSA:3.20.20.370 111 315 6.3E-64 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 GTHT12_RS06585 885f070bf634252e07fce24a64f4bd03 327 Pfam PF01522 Polysaccharide deacetylase 139 246 1.8E-32 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 GTHT12_RS06585 885f070bf634252e07fce24a64f4bd03 327 SUPERFAMILY SSF88713 118 313 6.67E-60 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 GTHT12_RS14255 1d9e7ad23bcb5e34ff4b353b6be71ea5 319 PIRSF PIRSF000532 1 319 1.5E-127 T 06-07-2017 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 GTHT12_RS14255 1d9e7ad23bcb5e34ff4b353b6be71ea5 319 Gene3D G3DSA:3.40.50.450 1 214 2.0E-79 T 06-07-2017 GTHT12_RS14255 1d9e7ad23bcb5e34ff4b353b6be71ea5 319 Pfam PF00365 Phosphofructokinase 3 275 9.5E-117 T 06-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 GTHT12_RS14255 1d9e7ad23bcb5e34ff4b353b6be71ea5 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 1.2E-92 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 GTHT12_RS14255 1d9e7ad23bcb5e34ff4b353b6be71ea5 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 1.2E-92 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 GTHT12_RS14255 1d9e7ad23bcb5e34ff4b353b6be71ea5 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 1.2E-92 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 GTHT12_RS14255 1d9e7ad23bcb5e34ff4b353b6be71ea5 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 1.2E-92 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 GTHT12_RS14255 1d9e7ad23bcb5e34ff4b353b6be71ea5 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 1.2E-92 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 GTHT12_RS14255 1d9e7ad23bcb5e34ff4b353b6be71ea5 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 1.2E-92 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 GTHT12_RS14255 1d9e7ad23bcb5e34ff4b353b6be71ea5 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 239 261 1.2E-92 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 GTHT12_RS14255 1d9e7ad23bcb5e34ff4b353b6be71ea5 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 1.2E-92 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 GTHT12_RS14255 1d9e7ad23bcb5e34ff4b353b6be71ea5 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 1.2E-92 T 06-07-2017 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 GTHT12_RS14255 1d9e7ad23bcb5e34ff4b353b6be71ea5 319 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 318 50.083 T 06-07-2017 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 GTHT12_RS14255 1d9e7ad23bcb5e34ff4b353b6be71ea5 319 ProSitePatterns PS00433 Phosphofructokinase signature. 243 261 - T 06-07-2017 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 GTHT12_RS14255 1d9e7ad23bcb5e34ff4b353b6be71ea5 319 SUPERFAMILY SSF53784 1 316 2.35E-122 T 06-07-2017 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 GTHT12_RS14255 1d9e7ad23bcb5e34ff4b353b6be71ea5 319 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 299 1.2E-143 T 06-07-2017 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 GTHT12_RS18525 916945801147cba0a54512f09b3dc457 77 SUPERFAMILY SSF56349 15 74 1.5E-13 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 GTHT12_RS18525 916945801147cba0a54512f09b3dc457 77 Pfam PF00589 Phage integrase family 18 63 5.7E-10 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS18525 916945801147cba0a54512f09b3dc457 77 Gene3D G3DSA:1.10.443.10 7 75 6.9E-15 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS00595 b779d64af48104374719a999bbfda076 163 SMART SM00649 31 162 6.7E-89 T 06-07-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00595 b779d64af48104374719a999bbfda076 163 SUPERFAMILY SSF46906 89 162 1.83E-27 T 06-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00595 b779d64af48104374719a999bbfda076 163 Gene3D G3DSA:1.10.10.250 94 162 9.5E-33 T 06-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00595 b779d64af48104374719a999bbfda076 163 Pfam PF03946 Ribosomal protein L11, N-terminal domain 31 88 1.7E-31 T 06-07-2017 IPR020784 Ribosomal protein L11, N-terminal GTHT12_RS00595 b779d64af48104374719a999bbfda076 163 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 27 163 32.2 T 06-07-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00595 b779d64af48104374719a999bbfda076 163 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 58 95 1.0E-15 T 06-07-2017 GTHT12_RS00595 b779d64af48104374719a999bbfda076 163 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 25 163 4.0E-66 T 06-07-2017 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00595 b779d64af48104374719a999bbfda076 163 ProSitePatterns PS00359 Ribosomal protein L11 signature. 148 163 - T 06-07-2017 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00595 b779d64af48104374719a999bbfda076 163 Pfam PF00298 Ribosomal protein L11, RNA binding domain 93 161 4.7E-26 T 06-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00595 b779d64af48104374719a999bbfda076 163 SUPERFAMILY SSF54747 23 106 6.15E-31 T 06-07-2017 IPR020784 Ribosomal protein L11, N-terminal GTHT12_RS00595 b779d64af48104374719a999bbfda076 163 Gene3D G3DSA:3.30.1550.10 24 93 2.5E-39 T 06-07-2017 IPR020784 Ribosomal protein L11, N-terminal GTHT12_RS07260 252df5a4295d190025e2bedbe634e251 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.3E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS07260 252df5a4295d190025e2bedbe634e251 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.3E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS07260 252df5a4295d190025e2bedbe634e251 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.3E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS07260 252df5a4295d190025e2bedbe634e251 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.3E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS07260 252df5a4295d190025e2bedbe634e251 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.3E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS07260 252df5a4295d190025e2bedbe634e251 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.3E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS07260 252df5a4295d190025e2bedbe634e251 252 SUPERFAMILY SSF51735 1 251 5.19E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS07260 252df5a4295d190025e2bedbe634e251 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.7E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS07260 252df5a4295d190025e2bedbe634e251 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.7E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS07260 252df5a4295d190025e2bedbe634e251 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.7E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS07260 252df5a4295d190025e2bedbe634e251 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 250 1.7E-69 T 06-07-2017 GTHT12_RS07260 252df5a4295d190025e2bedbe634e251 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GTHT12_RS07260 252df5a4295d190025e2bedbe634e251 252 Gene3D G3DSA:3.40.50.720 2 251 1.4E-84 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS01595 baf7ddc2f09aa34dcb87ac6a81c092d8 382 SUPERFAMILY SSF52440 9 98 1.73E-26 T 06-07-2017 IPR016185 Pre-ATP-grasp domain GTHT12_RS01595 baf7ddc2f09aa34dcb87ac6a81c092d8 382 SUPERFAMILY SSF51246 309 376 1.49E-16 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GTHT12_RS01595 baf7ddc2f09aa34dcb87ac6a81c092d8 382 Pfam PF02222 ATP-grasp domain 117 285 1.4E-59 T 06-07-2017 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type GTHT12_RS01595 baf7ddc2f09aa34dcb87ac6a81c092d8 382 Gene3D G3DSA:3.40.50.20 6 113 1.8E-34 T 06-07-2017 IPR016185 Pre-ATP-grasp domain GTHT12_RS01595 baf7ddc2f09aa34dcb87ac6a81c092d8 382 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 11 364 3.2E-131 T 06-07-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 GTHT12_RS01595 baf7ddc2f09aa34dcb87ac6a81c092d8 382 Gene3D G3DSA:3.30.1490.20 117 160 2.4E-8 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GTHT12_RS01595 baf7ddc2f09aa34dcb87ac6a81c092d8 382 Gene3D G3DSA:3.30.470.20 161 376 2.3E-88 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 GTHT12_RS01595 baf7ddc2f09aa34dcb87ac6a81c092d8 382 SUPERFAMILY SSF56059 107 305 1.11E-65 T 06-07-2017 GTHT12_RS01595 baf7ddc2f09aa34dcb87ac6a81c092d8 382 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 11 361 44.152 T 06-07-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 GTHT12_RS11825 a523784e3e0b4691b806c707fd1f9bad 323 Gene3D G3DSA:3.40.50.40 212 320 3.5E-26 T 06-07-2017 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 GTHT12_RS11825 a523784e3e0b4691b806c707fd1f9bad 323 Gene3D G3DSA:3.40.50.1170 3 211 5.7E-56 T 06-07-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 GTHT12_RS11825 a523784e3e0b4691b806c707fd1f9bad 323 SUPERFAMILY SSF53774 3 320 1.7E-88 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 GTHT12_RS11825 a523784e3e0b4691b806c707fd1f9bad 323 PIRSF PIRSF500176 2 322 1.6E-86 T 06-07-2017 GTHT12_RS11825 a523784e3e0b4691b806c707fd1f9bad 323 Pfam PF00710 Asparaginase, N-terminal 5 196 6.1E-53 T 06-07-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 GTHT12_RS11825 a523784e3e0b4691b806c707fd1f9bad 323 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 8 16 - T 06-07-2017 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 GTHT12_RS11825 a523784e3e0b4691b806c707fd1f9bad 323 PRINTS PR00139 Asparaginase/glutaminase family signature 83 101 1.9E-19 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 GTHT12_RS11825 a523784e3e0b4691b806c707fd1f9bad 323 PRINTS PR00139 Asparaginase/glutaminase family signature 6 17 1.9E-19 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 GTHT12_RS11825 a523784e3e0b4691b806c707fd1f9bad 323 PRINTS PR00139 Asparaginase/glutaminase family signature 256 274 1.9E-19 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 GTHT12_RS11825 a523784e3e0b4691b806c707fd1f9bad 323 PIRSF PIRSF001220 1 322 7.1E-91 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 GTHT12_RS11825 a523784e3e0b4691b806c707fd1f9bad 323 SMART SM00870 5 321 2.1E-114 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 GTHT12_RS11585 06f93418c4a4f8a83091d210744dc4d9 254 SUPERFAMILY SSF46626 132 251 3.87E-15 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GTHT12_RS11585 06f93418c4a4f8a83091d210744dc4d9 254 Gene3D G3DSA:1.20.810.10 29 156 2.7E-22 T 06-07-2017 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 GTHT12_RS11585 06f93418c4a4f8a83091d210744dc4d9 254 PIRSF PIRSF036636 1 254 1.1E-152 T 06-07-2017 IPR012049 Menaquinone:cytochrome c reductase, cytochrome b/c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 GTHT12_RS11585 06f93418c4a4f8a83091d210744dc4d9 254 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 71 157 2.4E-10 T 06-07-2017 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 GTHT12_RS11585 06f93418c4a4f8a83091d210744dc4d9 254 Gene3D G3DSA:1.10.760.10 182 251 1.2E-16 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GTHT12_RS11585 06f93418c4a4f8a83091d210744dc4d9 254 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 181 248 4.8E-14 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GTHT12_RS11585 06f93418c4a4f8a83091d210744dc4d9 254 SUPERFAMILY SSF81648 21 159 9.29E-31 T 06-07-2017 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 GTHT12_RS12885 8d39bd7d997b94450d5f7f89a94ce49f 281 SUPERFAMILY SSF52540 30 268 1.13E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12885 8d39bd7d997b94450d5f7f89a94ce49f 281 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 35 281 2.3E-126 T 06-07-2017 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 GTHT12_RS12885 8d39bd7d997b94450d5f7f89a94ce49f 281 Gene3D G3DSA:3.40.50.300 36 275 3.9E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12885 8d39bd7d997b94450d5f7f89a94ce49f 281 Pfam PF00005 ABC transporter 50 206 2.7E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS12885 8d39bd7d997b94450d5f7f89a94ce49f 281 ProSitePatterns PS00211 ABC transporters family signature. 178 192 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS12885 8d39bd7d997b94450d5f7f89a94ce49f 281 SMART SM00382 59 253 1.6E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS15750 af0f4ec24a917cafe6614acc56936929 331 Gene3D G3DSA:3.40.190.10 130 261 4.1E-39 T 06-07-2017 GTHT12_RS15750 af0f4ec24a917cafe6614acc56936929 331 Pfam PF16868 NMT1-like family 48 327 4.3E-90 T 06-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family GTHT12_RS15750 af0f4ec24a917cafe6614acc56936929 331 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 3 327 2.7E-110 T 06-07-2017 IPR011852 TRAP transporter solute receptor, TAXI family GTHT12_RS15750 af0f4ec24a917cafe6614acc56936929 331 Gene3D G3DSA:3.40.190.10 44 123 6.8E-54 T 06-07-2017 GTHT12_RS15750 af0f4ec24a917cafe6614acc56936929 331 Gene3D G3DSA:3.40.190.10 262 328 6.8E-54 T 06-07-2017 GTHT12_RS15750 af0f4ec24a917cafe6614acc56936929 331 SUPERFAMILY SSF53850 44 328 4.81E-79 T 06-07-2017 GTHT12_RS00785 fdeff7ee8c646207fa6ea671afc31f7b 121 PIRSF PIRSF002134 1 121 1.2E-43 T 06-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00785 fdeff7ee8c646207fa6ea671afc31f7b 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 7.5E-36 T 06-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00785 fdeff7ee8c646207fa6ea671afc31f7b 121 Gene3D G3DSA:1.10.8.50 1 71 4.5E-32 T 06-07-2017 GTHT12_RS00785 fdeff7ee8c646207fa6ea671afc31f7b 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 29.081 T 06-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00785 fdeff7ee8c646207fa6ea671afc31f7b 121 SUPERFAMILY SSF46946 2 120 3.24E-46 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 GTHT12_RS00785 fdeff7ee8c646207fa6ea671afc31f7b 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 2.3E-54 T 06-07-2017 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00785 fdeff7ee8c646207fa6ea671afc31f7b 121 Gene3D G3DSA:4.10.910.10 72 121 8.8E-29 T 06-07-2017 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00785 fdeff7ee8c646207fa6ea671afc31f7b 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 06-07-2017 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS07695 873292078fbd2baf79e3eb3db86773d1 337 Gene3D G3DSA:3.30.70.260 237 335 9.1E-27 T 06-07-2017 GTHT12_RS07695 873292078fbd2baf79e3eb3db86773d1 337 SMART SM00930 258 333 7.7E-25 T 06-07-2017 IPR018449 NIL domain GTHT12_RS07695 873292078fbd2baf79e3eb3db86773d1 337 Pfam PF00005 ABC transporter 21 169 5.6E-38 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS07695 873292078fbd2baf79e3eb3db86773d1 337 Pfam PF09383 NIL domain 260 332 1.5E-19 T 06-07-2017 IPR018449 NIL domain GTHT12_RS07695 873292078fbd2baf79e3eb3db86773d1 337 SUPERFAMILY SSF52540 1 240 2.24E-88 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07695 873292078fbd2baf79e3eb3db86773d1 337 Gene3D G3DSA:3.40.50.300 1 236 1.1E-91 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07695 873292078fbd2baf79e3eb3db86773d1 337 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS07695 873292078fbd2baf79e3eb3db86773d1 337 SMART SM00382 30 218 1.3E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS07695 873292078fbd2baf79e3eb3db86773d1 337 SUPERFAMILY SSF55021 250 335 1.95E-20 T 06-07-2017 GTHT12_RS00300 846a7583039b89b05bb9fd580e37b9fb 178 SUPERFAMILY SSF89447 1 52 9.03E-15 T 06-07-2017 GTHT12_RS00300 846a7583039b89b05bb9fd580e37b9fb 178 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 51 1.1E-10 T 06-07-2017 IPR007159 SpoVT-AbrB domain GO:0003677 GTHT12_RS00300 846a7583039b89b05bb9fd580e37b9fb 178 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 1.2E-15 T 06-07-2017 IPR007159 SpoVT-AbrB domain GO:0003677 GTHT12_RS00300 846a7583039b89b05bb9fd580e37b9fb 178 TIGRFAM TIGR02851 spore_V_T: stage V sporulation protein T 2 177 1.4E-90 T 06-07-2017 IPR014213 Sporulation stage V, protein T GTHT12_RS00300 846a7583039b89b05bb9fd580e37b9fb 178 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 54 177 4.8E-45 T 06-07-2017 GTHT12_RS00300 846a7583039b89b05bb9fd580e37b9fb 178 Gene3D G3DSA:2.10.260.10 1 52 5.3E-29 T 06-07-2017 GTHT12_RS00300 846a7583039b89b05bb9fd580e37b9fb 178 SMART SM00966 8 52 1.1E-10 T 06-07-2017 IPR007159 SpoVT-AbrB domain GO:0003677 GTHT12_RS00300 846a7583039b89b05bb9fd580e37b9fb 178 PIRSF PIRSF026579 1 178 4.8E-96 T 06-07-2017 IPR014213 Sporulation stage V, protein T GTHT12_RS03715 d9cab6adae53d5e3c6217e5edec5d8fa 244 SUPERFAMILY SSF56281 1 242 3.14E-58 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS03715 d9cab6adae53d5e3c6217e5edec5d8fa 244 SMART SM00849 18 211 1.4E-10 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS03715 d9cab6adae53d5e3c6217e5edec5d8fa 244 Gene3D G3DSA:3.60.15.10 1 243 9.3E-62 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS03715 d9cab6adae53d5e3c6217e5edec5d8fa 244 Pfam PF12706 Beta-lactamase superfamily domain 30 211 1.3E-22 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS17290 bf5e7f50fc3a35e20ef87a0c4e72e6e6 294 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 263 2.2E-120 T 06-07-2017 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 GTHT12_RS17290 bf5e7f50fc3a35e20ef87a0c4e72e6e6 294 Gene3D G3DSA:3.90.550.10 5 273 3.9E-77 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS17290 bf5e7f50fc3a35e20ef87a0c4e72e6e6 294 SUPERFAMILY SSF53448 3 267 1.19E-70 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS17290 bf5e7f50fc3a35e20ef87a0c4e72e6e6 294 Pfam PF00483 Nucleotidyl transferase 6 258 3.8E-36 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 GTHT12_RS12365 96856f068fd5c729a2460ecb6b5a84a1 516 SUPERFAMILY SSF52096 2 257 3.98E-84 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS12365 96856f068fd5c729a2460ecb6b5a84a1 516 Pfam PF01039 Carboxyl transferase domain 29 514 5.8E-198 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GTHT12_RS12365 96856f068fd5c729a2460ecb6b5a84a1 516 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 130 148 3.5E-5 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 GTHT12_RS12365 96856f068fd5c729a2460ecb6b5a84a1 516 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 96 110 3.5E-5 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 GTHT12_RS12365 96856f068fd5c729a2460ecb6b5a84a1 516 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 195 206 3.5E-5 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 GTHT12_RS12365 96856f068fd5c729a2460ecb6b5a84a1 516 SUPERFAMILY SSF52096 244 516 6.12E-91 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS12365 96856f068fd5c729a2460ecb6b5a84a1 516 Gene3D G3DSA:3.90.226.10 3 257 3.0E-86 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS12365 96856f068fd5c729a2460ecb6b5a84a1 516 Gene3D G3DSA:3.90.226.10 270 516 2.1E-110 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS01455 c8f6a201da6fff7643890524ed1d6028 213 Pfam PF06971 Putative DNA-binding protein N-terminus 7 55 3.3E-20 T 06-07-2017 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 GTHT12_RS01455 c8f6a201da6fff7643890524ed1d6028 213 Gene3D G3DSA:3.40.50.720 80 209 3.2E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS01455 c8f6a201da6fff7643890524ed1d6028 213 Pfam PF02629 CoA binding domain 84 179 2.5E-29 T 06-07-2017 IPR003781 CoA-binding GO:0048037 GTHT12_RS01455 c8f6a201da6fff7643890524ed1d6028 213 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 3 210 38.864 T 06-07-2017 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 GTHT12_RS01455 c8f6a201da6fff7643890524ed1d6028 213 SMART SM00881 82 181 2.1E-17 T 06-07-2017 IPR003781 CoA-binding GO:0048037 GTHT12_RS01455 c8f6a201da6fff7643890524ed1d6028 213 SUPERFAMILY SSF46785 9 80 6.65E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS01455 c8f6a201da6fff7643890524ed1d6028 213 SUPERFAMILY SSF51735 84 207 3.74E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS01455 c8f6a201da6fff7643890524ed1d6028 213 Gene3D G3DSA:1.10.10.10 7 77 1.3E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS11670 bcf3f8ccf9689175fd2a8071c3919282 388 Hamap MF_00300 Chorismate synthase [aroC]. 1 370 36.834 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 GTHT12_RS11670 bcf3f8ccf9689175fd2a8071c3919282 388 Gene3D G3DSA:3.60.150.10 1 386 2.3E-157 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 GTHT12_RS11670 bcf3f8ccf9689175fd2a8071c3919282 388 ProSitePatterns PS00789 Chorismate synthase signature 3. 337 353 - T 06-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 GTHT12_RS11670 bcf3f8ccf9689175fd2a8071c3919282 388 PIRSF PIRSF001456 1 382 1.7E-132 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 GTHT12_RS11670 bcf3f8ccf9689175fd2a8071c3919282 388 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 06-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 GTHT12_RS11670 bcf3f8ccf9689175fd2a8071c3919282 388 ProSitePatterns PS00788 Chorismate synthase signature 2. 129 145 - T 06-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 GTHT12_RS11670 bcf3f8ccf9689175fd2a8071c3919282 388 SUPERFAMILY SSF103263 1 387 6.02E-152 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 GTHT12_RS11670 bcf3f8ccf9689175fd2a8071c3919282 388 Pfam PF01264 Chorismate synthase 1 362 1.3E-125 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 GTHT12_RS11670 bcf3f8ccf9689175fd2a8071c3919282 388 TIGRFAM TIGR00033 aroC: chorismate synthase 1 368 1.4E-131 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 GTHT12_RS01895 7e8012109df8081fc73972e2ed72c83e 489 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 414 434 - T 06-07-2017 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 GTHT12_RS01895 7e8012109df8081fc73972e2ed72c83e 489 TIGRFAM TIGR02119 panF: sodium/pantothenate symporter 3 472 1.3E-223 T 06-07-2017 IPR011849 Sodium/pantothenate symporter GO:0015081|GO:0015233|GO:0015887|GO:0016021|GO:0031402|GO:0071436 GTHT12_RS01895 7e8012109df8081fc73972e2ed72c83e 489 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 37 432 1.6E-89 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 GTHT12_RS01895 7e8012109df8081fc73972e2ed72c83e 489 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 156 181 - T 06-07-2017 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 GTHT12_RS01895 7e8012109df8081fc73972e2ed72c83e 489 Pfam PF00474 Sodium:solute symporter family 37 432 6.6E-102 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 GTHT12_RS12915 9455b08aaac41d37a8009cad73b9b061 204 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 90 2.0E-34 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS12915 9455b08aaac41d37a8009cad73b9b061 204 PRINTS PR01703 Manganese superoxide dismutase signature 162 174 8.4E-28 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS12915 9455b08aaac41d37a8009cad73b9b061 204 PRINTS PR01703 Manganese superoxide dismutase signature 73 86 8.4E-28 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS12915 9455b08aaac41d37a8009cad73b9b061 204 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 8.4E-28 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS12915 9455b08aaac41d37a8009cad73b9b061 204 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 8.4E-28 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS12915 9455b08aaac41d37a8009cad73b9b061 204 PRINTS PR01703 Manganese superoxide dismutase signature 126 134 8.4E-28 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS12915 9455b08aaac41d37a8009cad73b9b061 204 SUPERFAMILY SSF46609 1 91 2.49E-38 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS12915 9455b08aaac41d37a8009cad73b9b061 204 Gene3D G3DSA:1.10.287.990 20 90 6.4E-33 T 06-07-2017 GTHT12_RS12915 9455b08aaac41d37a8009cad73b9b061 204 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 97 197 1.4E-44 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS12915 9455b08aaac41d37a8009cad73b9b061 204 PIRSF PIRSF000349 1 204 6.4E-90 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS12915 9455b08aaac41d37a8009cad73b9b061 204 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 164 171 - T 06-07-2017 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS12915 9455b08aaac41d37a8009cad73b9b061 204 SUPERFAMILY SSF54719 92 201 4.98E-50 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS06005 b37d40662a874e4f0946aedfe9a97b1d 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 214 223 9.8E-12 T 06-07-2017 GTHT12_RS06005 b37d40662a874e4f0946aedfe9a97b1d 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 241 252 9.8E-12 T 06-07-2017 GTHT12_RS06005 b37d40662a874e4f0946aedfe9a97b1d 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 327 340 9.8E-12 T 06-07-2017 GTHT12_RS06005 b37d40662a874e4f0946aedfe9a97b1d 364 Pfam PF00117 Glutamine amidotransferase class-I 173 349 3.9E-46 T 06-07-2017 IPR017926 Glutamine amidotransferase GTHT12_RS06005 b37d40662a874e4f0946aedfe9a97b1d 364 Gene3D G3DSA:3.50.30.20 2 140 7.8E-60 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS06005 b37d40662a874e4f0946aedfe9a97b1d 364 SMART SM01097 1 131 3.9E-92 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS06005 b37d40662a874e4f0946aedfe9a97b1d 364 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 356 49.401 T 06-07-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS06005 b37d40662a874e4f0946aedfe9a97b1d 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 241 257 2.2E-37 T 06-07-2017 GTHT12_RS06005 b37d40662a874e4f0946aedfe9a97b1d 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 172 186 2.2E-37 T 06-07-2017 GTHT12_RS06005 b37d40662a874e4f0946aedfe9a97b1d 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 211 225 2.2E-37 T 06-07-2017 GTHT12_RS06005 b37d40662a874e4f0946aedfe9a97b1d 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 283 294 2.2E-37 T 06-07-2017 GTHT12_RS06005 b37d40662a874e4f0946aedfe9a97b1d 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 258 275 2.2E-37 T 06-07-2017 GTHT12_RS06005 b37d40662a874e4f0946aedfe9a97b1d 364 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 353 1.4E-145 T 06-07-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS06005 b37d40662a874e4f0946aedfe9a97b1d 364 PRINTS PR00097 Anthranilate synthase component II signature 214 223 1.7E-6 T 06-07-2017 GTHT12_RS06005 b37d40662a874e4f0946aedfe9a97b1d 364 PRINTS PR00097 Anthranilate synthase component II signature 241 252 1.7E-6 T 06-07-2017 GTHT12_RS06005 b37d40662a874e4f0946aedfe9a97b1d 364 PRINTS PR00097 Anthranilate synthase component II signature 327 340 1.7E-6 T 06-07-2017 GTHT12_RS06005 b37d40662a874e4f0946aedfe9a97b1d 364 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 130 2.7E-53 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS06005 b37d40662a874e4f0946aedfe9a97b1d 364 SUPERFAMILY SSF52021 1 141 6.15E-58 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 GTHT12_RS06005 b37d40662a874e4f0946aedfe9a97b1d 364 SUPERFAMILY SSF52317 150 355 1.83E-56 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS06005 b37d40662a874e4f0946aedfe9a97b1d 364 Gene3D G3DSA:3.40.50.880 152 355 3.5E-68 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS06790 fc3f1977117dbc3863f727c1c697a8c9 563 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 337 561 2.0E-56 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 GTHT12_RS06790 fc3f1977117dbc3863f727c1c697a8c9 563 Gene3D G3DSA:1.10.287.950 302 519 4.1E-58 T 06-07-2017 GTHT12_RS06790 fc3f1977117dbc3863f727c1c697a8c9 563 SMART SM00304 503 559 91.0 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS06790 fc3f1977117dbc3863f727c1c697a8c9 563 SMART SM00304 205 258 8.4E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS06790 fc3f1977117dbc3863f727c1c697a8c9 563 Pfam PF12729 Four helix bundle sensory module for signal transduction 2 177 5.1E-14 T 06-07-2017 IPR024478 4HB MCP domain GTHT12_RS06790 fc3f1977117dbc3863f727c1c697a8c9 563 SMART SM00283 287 562 5.8E-96 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 GTHT12_RS06790 fc3f1977117dbc3863f727c1c697a8c9 563 Pfam PF00672 HAMP domain 186 254 4.2E-18 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS06790 fc3f1977117dbc3863f727c1c697a8c9 563 SUPERFAMILY SSF58104 230 260 4.05E-76 T 06-07-2017 GTHT12_RS06790 fc3f1977117dbc3863f727c1c697a8c9 563 SUPERFAMILY SSF58104 293 561 4.05E-76 T 06-07-2017 GTHT12_RS01875 bba6c1cad20e5604133cf30977984fb3 457 SUPERFAMILY SSF55874 289 456 5.37E-50 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS01875 bba6c1cad20e5604133cf30977984fb3 457 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 456 3.2E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS01875 bba6c1cad20e5604133cf30977984fb3 457 SMART SM00388 232 300 3.3E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS01875 bba6c1cad20e5604133cf30977984fb3 457 Gene3D G3DSA:1.10.287.130 226 285 1.0E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS01875 bba6c1cad20e5604133cf30977984fb3 457 Pfam PF00512 His Kinase A (phospho-acceptor) domain 233 299 1.1E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS01875 bba6c1cad20e5604133cf30977984fb3 457 Gene3D G3DSA:3.30.565.10 286 457 1.4E-49 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS01875 bba6c1cad20e5604133cf30977984fb3 457 SMART SM00387 347 457 6.3E-41 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS01875 bba6c1cad20e5604133cf30977984fb3 457 SUPERFAMILY SSF47384 221 300 7.65E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS01875 bba6c1cad20e5604133cf30977984fb3 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 412 2.3E-19 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS01875 bba6c1cad20e5604133cf30977984fb3 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 456 2.3E-19 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS01875 bba6c1cad20e5604133cf30977984fb3 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 398 2.3E-19 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS01875 bba6c1cad20e5604133cf30977984fb3 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 437 2.3E-19 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS14065 0e5a93b696289b411597c24c837e3bbe 1054 SUPERFAMILY SSF82866 127 341 1.96E-31 T 06-07-2017 GTHT12_RS14065 0e5a93b696289b411597c24c837e3bbe 1054 SUPERFAMILY SSF82866 833 1037 6.54E-33 T 06-07-2017 GTHT12_RS14065 0e5a93b696289b411597c24c837e3bbe 1054 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 511 537 2.0E-4 T 06-07-2017 IPR023908 xxxLxxG heptad repeat GTHT12_RS14065 0e5a93b696289b411597c24c837e3bbe 1054 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 552 579 2.0E-4 T 06-07-2017 IPR023908 xxxLxxG heptad repeat GTHT12_RS14065 0e5a93b696289b411597c24c837e3bbe 1054 Pfam PF03176 MMPL family 743 1038 5.6E-47 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 GTHT12_RS14065 0e5a93b696289b411597c24c837e3bbe 1054 Pfam PF03176 MMPL family 42 366 5.1E-60 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 GTHT12_RS14065 0e5a93b696289b411597c24c837e3bbe 1054 Gene3D G3DSA:1.20.1640.10 831 1037 2.3E-25 T 06-07-2017 GTHT12_RS14065 0e5a93b696289b411597c24c837e3bbe 1054 Gene3D G3DSA:1.20.1640.10 136 341 4.8E-29 T 06-07-2017 GTHT12_RS15285 aa58b60aa9939bfd9215f04ce6664dce 387 SUPERFAMILY SSF56796 1 385 1.19E-118 T 06-07-2017 GTHT12_RS15285 aa58b60aa9939bfd9215f04ce6664dce 387 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 06-07-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 GTHT12_RS15285 aa58b60aa9939bfd9215f04ce6664dce 387 Gene3D G3DSA:1.20.1090.10 185 386 3.8E-56 T 06-07-2017 GTHT12_RS15285 aa58b60aa9939bfd9215f04ce6664dce 387 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 365 2.4E-104 T 06-07-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 GTHT12_RS15285 aa58b60aa9939bfd9215f04ce6664dce 387 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 264 284 - T 06-07-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 GTHT12_RS15285 aa58b60aa9939bfd9215f04ce6664dce 387 Gene3D G3DSA:3.40.50.1970 1 184 4.1E-65 T 06-07-2017 GTHT12_RS05450 8c6dfe7183b30e7464e5ab3aaef386a6 385 Pfam PF00155 Aminotransferase class I and II 30 374 3.0E-59 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 GTHT12_RS05450 8c6dfe7183b30e7464e5ab3aaef386a6 385 SUPERFAMILY SSF53383 5 380 2.29E-109 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS05450 8c6dfe7183b30e7464e5ab3aaef386a6 385 Gene3D G3DSA:3.40.640.10 42 249 3.1E-65 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS05450 8c6dfe7183b30e7464e5ab3aaef386a6 385 Gene3D G3DSA:3.90.1150.10 250 379 1.2E-43 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS05450 8c6dfe7183b30e7464e5ab3aaef386a6 385 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 227 240 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 GTHT12_RS09840 2e0aafb26e74a3572bb239b0e7ee79a6 371 Pfam PF03786 D-mannonate dehydratase (UxuA) 1 354 7.5E-158 T 06-07-2017 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 GTHT12_RS09840 2e0aafb26e74a3572bb239b0e7ee79a6 371 Hamap MF_00106 Mannonate dehydratase [uxuA]. 1 371 177.215 T 06-07-2017 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 GTHT12_RS09840 2e0aafb26e74a3572bb239b0e7ee79a6 371 PIRSF PIRSF016049 1 359 1.2E-123 T 06-07-2017 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 GTHT12_RS09840 2e0aafb26e74a3572bb239b0e7ee79a6 371 SUPERFAMILY SSF51658 1 352 9.51E-92 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain GTHT12_RS09840 2e0aafb26e74a3572bb239b0e7ee79a6 371 TIGRFAM TIGR00695 uxuA: mannonate dehydratase 1 355 3.7E-128 T 06-07-2017 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 GTHT12_RS09840 2e0aafb26e74a3572bb239b0e7ee79a6 371 Gene3D G3DSA:3.20.20.150 1 356 2.6E-148 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain GTHT12_RS09090 e1dc8d1502274d05394bcc5f77dabeac 636 Gene3D G3DSA:3.40.50.410 446 622 3.6E-7 T 06-07-2017 IPR002035 von Willebrand factor, type A GTHT12_RS09090 e1dc8d1502274d05394bcc5f77dabeac 636 Pfam PF11775 Cobalamin biosynthesis protein CobT VWA domain 518 559 2.5E-4 T 06-07-2017 IPR025861 Cobalamin biosynthesis protein CobT VWA domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 GTHT12_RS09090 e1dc8d1502274d05394bcc5f77dabeac 636 SUPERFAMILY SSF53300 446 628 9.2E-17 T 06-07-2017 IPR002035 von Willebrand factor, type A GTHT12_RS09090 e1dc8d1502274d05394bcc5f77dabeac 636 SMART SM00327 441 625 1.3E-7 T 06-07-2017 IPR002035 von Willebrand factor, type A GTHT12_RS04115 a37840438147c65ebb2983c1e5171ad2 135 Gene3D G3DSA:1.20.120.520 16 135 1.3E-5 T 06-07-2017 GTHT12_RS06100 26221180e324b5424770e45a82042407 444 SUPERFAMILY SSF48013 1 151 1.7E-37 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 GTHT12_RS06100 26221180e324b5424770e45a82042407 444 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 4 444 5.0E-154 T 06-07-2017 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS06100 26221180e324b5424770e45a82042407 444 SUPERFAMILY SSF53335 136 443 7.54E-81 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS06100 26221180e324b5424770e45a82042407 444 Gene3D G3DSA:3.40.50.150 234 443 1.0E-64 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS06100 26221180e324b5424770e45a82042407 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 425 442 1.2E-32 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS06100 26221180e324b5424770e45a82042407 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 371 387 1.2E-32 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS06100 26221180e324b5424770e45a82042407 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 253 263 1.2E-32 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS06100 26221180e324b5424770e45a82042407 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 321 333 1.2E-32 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS06100 26221180e324b5424770e45a82042407 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 224 238 1.2E-32 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS06100 26221180e324b5424770e45a82042407 444 Pfam PF01029 NusB family 1 123 9.7E-32 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 GTHT12_RS06100 26221180e324b5424770e45a82042407 444 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 320 331 - T 06-07-2017 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS06100 26221180e324b5424770e45a82042407 444 Pfam PF01189 16S rRNA methyltransferase RsmB/F 242 441 2.3E-64 T 06-07-2017 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS06100 26221180e324b5424770e45a82042407 444 Gene3D G3DSA:1.10.940.10 1 152 7.5E-47 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 GTHT12_RS06100 26221180e324b5424770e45a82042407 444 Gene3D G3DSA:3.30.70.1170 180 232 4.2E-6 T 06-07-2017 GTHT12_RS10510 73a669937e0fd9ffc025ad0e020b4177 348 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 50 302 5.3E-88 T 06-07-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 GTHT12_RS10510 73a669937e0fd9ffc025ad0e020b4177 348 PIRSF PIRSF006470 10 345 3.4E-125 T 06-07-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 GTHT12_RS10510 73a669937e0fd9ffc025ad0e020b4177 348 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 50 329 1.3E-100 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 GTHT12_RS03480 983859ab207a45ef59b4e42a7c4ae74b 394 Gene3D G3DSA:3.40.50.150 179 391 8.0E-67 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS03480 983859ab207a45ef59b4e42a7c4ae74b 394 Gene3D G3DSA:3.30.750.80 73 176 1.3E-36 T 06-07-2017 GTHT12_RS03480 983859ab207a45ef59b4e42a7c4ae74b 394 SUPERFAMILY SSF88697 1 70 3.09E-19 T 06-07-2017 IPR015947 PUA-like domain GTHT12_RS03480 983859ab207a45ef59b4e42a7c4ae74b 394 SUPERFAMILY SSF53335 78 383 2.67E-68 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS03480 983859ab207a45ef59b4e42a7c4ae74b 394 SMART SM00359 2 87 1.2E-11 T 06-07-2017 IPR002478 PUA domain GO:0003723 GTHT12_RS03480 983859ab207a45ef59b4e42a7c4ae74b 394 Gene3D G3DSA:2.30.130.10 1 70 2.9E-28 T 06-07-2017 IPR015947 PUA-like domain GTHT12_RS03480 983859ab207a45ef59b4e42a7c4ae74b 394 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 171 352 4.3E-20 T 06-07-2017 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 GTHT12_RS15925 0408b4558b47b6788ab4ea4c922e5b76 196 SUPERFAMILY SSF52096 10 193 9.95E-74 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS15925 0408b4558b47b6788ab4ea4c922e5b76 196 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 2 192 4.2E-108 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 GTHT12_RS15925 0408b4558b47b6788ab4ea4c922e5b76 196 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 45.078 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 GTHT12_RS15925 0408b4558b47b6788ab4ea4c922e5b76 196 Gene3D G3DSA:3.90.226.10 4 191 3.5E-89 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS15925 0408b4558b47b6788ab4ea4c922e5b76 196 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 8.7E-55 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 GTHT12_RS15925 0408b4558b47b6788ab4ea4c922e5b76 196 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 8.7E-55 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 GTHT12_RS15925 0408b4558b47b6788ab4ea4c922e5b76 196 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 8.7E-55 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 GTHT12_RS15925 0408b4558b47b6788ab4ea4c922e5b76 196 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 8.7E-55 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 GTHT12_RS15925 0408b4558b47b6788ab4ea4c922e5b76 196 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 8.7E-55 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 GTHT12_RS15925 0408b4558b47b6788ab4ea4c922e5b76 196 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 06-07-2017 IPR018215 ClpP, Ser active site GTHT12_RS15925 0408b4558b47b6788ab4ea4c922e5b76 196 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 06-07-2017 IPR033135 ClpP, histidine active site GTHT12_RS15925 0408b4558b47b6788ab4ea4c922e5b76 196 Pfam PF00574 Clp protease 13 191 2.8E-87 T 06-07-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA GTHT12_RS00250 1b654f97257409827324f88b3a3dd198 273 Pfam PF00156 Phosphoribosyl transferase domain 108 260 2.1E-21 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 GTHT12_RS00250 1b654f97257409827324f88b3a3dd198 273 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 9 74 2.0E-31 T 06-07-2017 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 GTHT12_RS00250 1b654f97257409827324f88b3a3dd198 273 Pfam PF09182 Bacterial purine repressor, N-terminal 4 73 8.6E-32 T 06-07-2017 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 GTHT12_RS00250 1b654f97257409827324f88b3a3dd198 273 Gene3D G3DSA:3.40.50.2020 84 263 1.3E-55 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS00250 1b654f97257409827324f88b3a3dd198 273 Gene3D G3DSA:1.10.10.10 1 73 1.2E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS00250 1b654f97257409827324f88b3a3dd198 273 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 3 269 9.1E-122 T 06-07-2017 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 GTHT12_RS00250 1b654f97257409827324f88b3a3dd198 273 SUPERFAMILY SSF53271 91 267 7.95E-42 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS00250 1b654f97257409827324f88b3a3dd198 273 SUPERFAMILY SSF46785 2 73 1.25E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS07655 432cb91538bb8b0948dcd2a656ea8768 613 Gene3D G3DSA:3.40.50.720 402 533 3.1E-13 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS07655 432cb91538bb8b0948dcd2a656ea8768 613 SUPERFAMILY SSF51735 404 514 1.85E-10 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS07655 432cb91538bb8b0948dcd2a656ea8768 613 Pfam PF02254 TrkA-N domain 404 513 8.0E-8 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 GTHT12_RS07655 432cb91538bb8b0948dcd2a656ea8768 613 Pfam PF02080 TrkA-C domain 550 609 1.0E-12 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 GTHT12_RS07655 432cb91538bb8b0948dcd2a656ea8768 613 Gene3D G3DSA:3.30.70.1450 554 611 7.6E-9 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 GTHT12_RS07655 432cb91538bb8b0948dcd2a656ea8768 613 Pfam PF00999 Sodium/hydrogen exchanger family 11 389 2.0E-69 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 GTHT12_RS07655 432cb91538bb8b0948dcd2a656ea8768 613 SUPERFAMILY SSF116726 533 608 5.1E-13 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 GTHT12_RS17600 ffd5a8a4f3e2ea0ad3eca3a1330a7fe0 428 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 414 8.1E-169 T 06-07-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS17600 ffd5a8a4f3e2ea0ad3eca3a1330a7fe0 428 SUPERFAMILY SSF55205 1 415 2.45E-136 T 06-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 GTHT12_RS17600 ffd5a8a4f3e2ea0ad3eca3a1330a7fe0 428 Gene3D G3DSA:3.65.10.10 220 415 3.7E-62 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 GTHT12_RS17600 ffd5a8a4f3e2ea0ad3eca3a1330a7fe0 428 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 405 2.7E-93 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 GTHT12_RS17600 ffd5a8a4f3e2ea0ad3eca3a1330a7fe0 428 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 415 43.158 T 06-07-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS17600 ffd5a8a4f3e2ea0ad3eca3a1330a7fe0 428 Gene3D G3DSA:3.65.10.10 21 219 3.2E-58 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 GTHT12_RS01140 ef12bb03971b805018a685cc79adab68 515 SUPERFAMILY SSF53720 4 511 5.24E-162 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GTHT12_RS01140 ef12bb03971b805018a685cc79adab68 515 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 313 324 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 GTHT12_RS01140 ef12bb03971b805018a685cc79adab68 515 Hamap MF_00733 1-pyrroline-5-carboxylate dehydrogenase [rocA]. 1 515 70.595 T 06-07-2017 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 GTHT12_RS01140 ef12bb03971b805018a685cc79adab68 515 Gene3D G3DSA:3.40.605.10 36 299 1.1E-89 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS01140 ef12bb03971b805018a685cc79adab68 515 Pfam PF00171 Aldehyde dehydrogenase family 50 511 3.4E-161 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS01140 ef12bb03971b805018a685cc79adab68 515 Gene3D G3DSA:3.40.309.10 300 485 7.4E-66 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 GTHT12_RS01140 ef12bb03971b805018a685cc79adab68 515 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 285 292 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 GTHT12_RS01140 ef12bb03971b805018a685cc79adab68 515 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 5 515 4.2E-262 T 06-07-2017 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 GTHT12_RS05430 ca18806972e3fec946d1a4eaccf6a7fd 191 SUPERFAMILY SSF48498 74 187 4.82E-25 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal GTHT12_RS05430 ca18806972e3fec946d1a4eaccf6a7fd 191 Gene3D G3DSA:1.10.357.10 46 187 1.1E-42 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 GTHT12_RS05430 ca18806972e3fec946d1a4eaccf6a7fd 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 1.0E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS05430 ca18806972e3fec946d1a4eaccf6a7fd 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 1.0E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS05430 ca18806972e3fec946d1a4eaccf6a7fd 191 SUPERFAMILY SSF46689 2 68 4.49E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS05430 ca18806972e3fec946d1a4eaccf6a7fd 191 ProSitePatterns PS01081 TetR-type HTH domain signature. 17 48 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site GTHT12_RS05430 ca18806972e3fec946d1a4eaccf6a7fd 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 5 48 2.6E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS05430 ca18806972e3fec946d1a4eaccf6a7fd 191 Gene3D G3DSA:1.10.10.60 2 45 7.0E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS05310 d9b0320eefa48598e7829540582b767a 195 Pfam PF07486 Cell Wall Hydrolase 92 193 7.8E-25 T 06-07-2017 IPR011105 Cell wall hydrolase, SleB GO:0016787 GTHT12_RS05310 d9b0320eefa48598e7829540582b767a 195 SMART SM00257 27 69 9.5E-16 T 06-07-2017 IPR018392 LysM domain GTHT12_RS05310 d9b0320eefa48598e7829540582b767a 195 Pfam PF01476 LysM domain 28 69 2.6E-12 T 06-07-2017 IPR018392 LysM domain GTHT12_RS05310 d9b0320eefa48598e7829540582b767a 195 SUPERFAMILY SSF54106 26 69 2.09E-12 T 06-07-2017 IPR018392 LysM domain GTHT12_RS05310 d9b0320eefa48598e7829540582b767a 195 Gene3D G3DSA:3.10.350.10 26 69 9.6E-18 T 06-07-2017 IPR018392 LysM domain GTHT12_RS12865 37af6d510fdec6c5c6c4792cd6f6d12c 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 3.5E-22 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS12865 37af6d510fdec6c5c6c4792cd6f6d12c 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 06-07-2017 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS12865 37af6d510fdec6c5c6c4792cd6f6d12c 49 Pfam PF00471 Ribosomal protein L33 3 49 6.0E-24 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS12865 37af6d510fdec6c5c6c4792cd6f6d12c 49 SUPERFAMILY SSF57829 1 49 1.22E-19 T 06-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 GTHT12_RS12865 37af6d510fdec6c5c6c4792cd6f6d12c 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 19.9 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS10200 29237eeedfdb4ed2c00703f3f1d43256 440 SUPERFAMILY SSF53850 13 430 5.43E-88 T 06-07-2017 GTHT12_RS10200 29237eeedfdb4ed2c00703f3f1d43256 440 Gene3D G3DSA:3.40.190.10 172 359 4.7E-48 T 06-07-2017 GTHT12_RS10200 29237eeedfdb4ed2c00703f3f1d43256 440 Pfam PF01547 Bacterial extracellular solute-binding protein 48 341 1.9E-44 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 GTHT12_RS10200 29237eeedfdb4ed2c00703f3f1d43256 440 Gene3D G3DSA:3.40.190.10 48 171 4.5E-24 T 06-07-2017 GTHT12_RS05905 69775c2e586f8a618ae1919e5f89f01d 422 SUPERFAMILY SSF53067 6 194 5.27E-58 T 06-07-2017 GTHT12_RS05905 69775c2e586f8a618ae1919e5f89f01d 422 SUPERFAMILY SSF53067 197 368 1.5E-41 T 06-07-2017 GTHT12_RS05905 69775c2e586f8a618ae1919e5f89f01d 422 Gene3D G3DSA:3.30.420.40 296 348 1.4E-26 T 06-07-2017 GTHT12_RS05905 69775c2e586f8a618ae1919e5f89f01d 422 Gene3D G3DSA:3.30.420.40 195 232 1.4E-26 T 06-07-2017 GTHT12_RS05905 69775c2e586f8a618ae1919e5f89f01d 422 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 369 4.2E-124 T 06-07-2017 IPR020823 Cell division protein FtsA GO:0007049 GTHT12_RS05905 69775c2e586f8a618ae1919e5f89f01d 422 Pfam PF02491 SHS2 domain inserted in FTSA 81 160 2.6E-27 T 06-07-2017 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 GTHT12_RS05905 69775c2e586f8a618ae1919e5f89f01d 422 PIRSF PIRSF003101 1 421 4.6E-148 T 06-07-2017 IPR020823 Cell division protein FtsA GO:0007049 GTHT12_RS05905 69775c2e586f8a618ae1919e5f89f01d 422 Gene3D G3DSA:3.30.420.40 1 137 8.7E-47 T 06-07-2017 GTHT12_RS05905 69775c2e586f8a618ae1919e5f89f01d 422 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 421 31.069 T 06-07-2017 IPR020823 Cell division protein FtsA GO:0007049 GTHT12_RS05905 69775c2e586f8a618ae1919e5f89f01d 422 SMART SM00842 7 194 2.5E-97 T 06-07-2017 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 GTHT12_RS05905 69775c2e586f8a618ae1919e5f89f01d 422 Gene3D G3DSA:3.90.640.10 233 295 1.2E-26 T 06-07-2017 GTHT12_RS05905 69775c2e586f8a618ae1919e5f89f01d 422 Pfam PF14450 Cell division protein FtsA 205 366 1.1E-21 T 06-07-2017 GTHT12_RS05905 69775c2e586f8a618ae1919e5f89f01d 422 Pfam PF14450 Cell division protein FtsA 9 187 4.2E-9 T 06-07-2017 GTHT12_RS06215 ad32cea07aba295c2e374522a96e6fb5 446 SMART SM00962 101 297 7.7E-126 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GTHT12_RS06215 ad32cea07aba295c2e374522a96e6fb5 446 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 434 36.344 T 06-07-2017 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 GTHT12_RS06215 ad32cea07aba295c2e374522a96e6fb5 446 SUPERFAMILY SSF52540 43 355 6.98E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06215 ad32cea07aba295c2e374522a96e6fb5 446 Gene3D G3DSA:1.10.260.30 328 431 7.2E-41 T 06-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 GTHT12_RS06215 ad32cea07aba295c2e374522a96e6fb5 446 Gene3D G3DSA:3.40.50.300 97 298 3.6E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06215 ad32cea07aba295c2e374522a96e6fb5 446 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GTHT12_RS06215 ad32cea07aba295c2e374522a96e6fb5 446 SUPERFAMILY SSF47446 328 430 2.45E-38 T 06-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 GTHT12_RS06215 ad32cea07aba295c2e374522a96e6fb5 446 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 1.5E-23 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GTHT12_RS06215 ad32cea07aba295c2e374522a96e6fb5 446 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 429 2.4E-194 T 06-07-2017 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 GTHT12_RS06215 ad32cea07aba295c2e374522a96e6fb5 446 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 5.2E-81 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GTHT12_RS06215 ad32cea07aba295c2e374522a96e6fb5 446 SMART SM00963 2 87 3.9E-35 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GTHT12_RS06215 ad32cea07aba295c2e374522a96e6fb5 446 SMART SM00382 100 302 2.0E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS06215 ad32cea07aba295c2e374522a96e6fb5 446 Gene3D G3DSA:1.20.120.140 3 91 1.4E-36 T 06-07-2017 GTHT12_RS06215 ad32cea07aba295c2e374522a96e6fb5 446 Pfam PF02978 Signal peptide binding domain 328 427 1.5E-34 T 06-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 GTHT12_RS04865 80d0590001b6d78d71d626fbb4130aa3 182 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 110 162 4.1E-8 T 06-07-2017 IPR019264 Domain of unknown function DUF2179 GTHT12_RS04865 80d0590001b6d78d71d626fbb4130aa3 182 Hamap MF_01515 UPF0316 protein . 2 170 29.494 T 06-07-2017 IPR022930 Protein of unknown function UPF0316 GTHT12_RS04865 80d0590001b6d78d71d626fbb4130aa3 182 Gene3D G3DSA:3.10.28.10 71 144 3.0E-4 T 06-07-2017 IPR027434 Homing endonuclease GO:0004519 GTHT12_RS00740 c7c6fddf9345f6f67cd2335ed3432aaa 120 Gene3D G3DSA:3.30.420.100 24 120 3.6E-46 T 06-07-2017 GTHT12_RS00740 c7c6fddf9345f6f67cd2335ed3432aaa 120 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 120 3.1E-55 T 06-07-2017 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00740 c7c6fddf9345f6f67cd2335ed3432aaa 120 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 120 31.706 T 06-07-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00740 c7c6fddf9345f6f67cd2335ed3432aaa 120 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 120 1.1E-49 T 06-07-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00740 c7c6fddf9345f6f67cd2335ed3432aaa 120 SUPERFAMILY SSF53137 7 118 1.48E-57 T 06-07-2017 GTHT12_RS06715 bc3e0634c23ad6e7acbbfefe153cdd09 346 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 4 323 1.4E-177 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 GTHT12_RS06715 bc3e0634c23ad6e7acbbfefe153cdd09 346 Hamap MF_00268 Protein RecA [recA]. 5 329 53.792 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 GTHT12_RS06715 bc3e0634c23ad6e7acbbfefe153cdd09 346 Pfam PF00154 recA bacterial DNA recombination protein 8 268 1.3E-147 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 GTHT12_RS06715 bc3e0634c23ad6e7acbbfefe153cdd09 346 ProSitePatterns PS00321 recA signature. 213 221 - T 06-07-2017 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 GTHT12_RS06715 bc3e0634c23ad6e7acbbfefe153cdd09 346 SMART SM00382 57 228 6.5E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS06715 bc3e0634c23ad6e7acbbfefe153cdd09 346 SUPERFAMILY SSF52540 7 267 1.6E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06715 bc3e0634c23ad6e7acbbfefe153cdd09 346 PRINTS PR00142 RecA protein signature 297 314 8.4E-86 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 GTHT12_RS06715 bc3e0634c23ad6e7acbbfefe153cdd09 346 PRINTS PR00142 RecA protein signature 93 122 8.4E-86 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 GTHT12_RS06715 bc3e0634c23ad6e7acbbfefe153cdd09 346 PRINTS PR00142 RecA protein signature 165 194 8.4E-86 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 GTHT12_RS06715 bc3e0634c23ad6e7acbbfefe153cdd09 346 PRINTS PR00142 RecA protein signature 243 272 8.4E-86 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 GTHT12_RS06715 bc3e0634c23ad6e7acbbfefe153cdd09 346 PRINTS PR00142 RecA protein signature 127 156 8.4E-86 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 GTHT12_RS06715 bc3e0634c23ad6e7acbbfefe153cdd09 346 PRINTS PR00142 RecA protein signature 210 238 8.4E-86 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 GTHT12_RS06715 bc3e0634c23ad6e7acbbfefe153cdd09 346 SUPERFAMILY SSF54752 268 327 1.31E-22 T 06-07-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal GTHT12_RS06715 bc3e0634c23ad6e7acbbfefe153cdd09 346 Gene3D G3DSA:3.40.50.300 27 267 2.3E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06715 bc3e0634c23ad6e7acbbfefe153cdd09 346 Gene3D G3DSA:3.30.250.10 268 326 4.5E-30 T 06-07-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal GTHT12_RS15455 6af498ef3a3219208bb70aac0394cc24 304 Gene3D G3DSA:3.30.230.10 6 151 2.9E-43 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GTHT12_RS15455 6af498ef3a3219208bb70aac0394cc24 304 TIGRFAM TIGR00191 thrB: homoserine kinase 7 299 1.1E-80 T 06-07-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 GTHT12_RS15455 6af498ef3a3219208bb70aac0394cc24 304 SUPERFAMILY SSF54211 6 151 8.35E-29 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS15455 6af498ef3a3219208bb70aac0394cc24 304 Gene3D G3DSA:3.30.70.890 163 291 1.5E-37 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain GTHT12_RS15455 6af498ef3a3219208bb70aac0394cc24 304 Pfam PF08544 GHMP kinases C terminal 204 281 1.1E-12 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain GTHT12_RS15455 6af498ef3a3219208bb70aac0394cc24 304 PIRSF PIRSF000676 4 300 3.3E-85 T 06-07-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 GTHT12_RS15455 6af498ef3a3219208bb70aac0394cc24 304 SUPERFAMILY SSF55060 164 283 1.35E-31 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain GTHT12_RS15455 6af498ef3a3219208bb70aac0394cc24 304 PRINTS PR00958 Homoserine kinase signature 168 185 2.5E-36 T 06-07-2017 GTHT12_RS15455 6af498ef3a3219208bb70aac0394cc24 304 PRINTS PR00958 Homoserine kinase signature 14 29 2.5E-36 T 06-07-2017 GTHT12_RS15455 6af498ef3a3219208bb70aac0394cc24 304 PRINTS PR00958 Homoserine kinase signature 248 263 2.5E-36 T 06-07-2017 GTHT12_RS15455 6af498ef3a3219208bb70aac0394cc24 304 PRINTS PR00958 Homoserine kinase signature 96 111 2.5E-36 T 06-07-2017 GTHT12_RS15455 6af498ef3a3219208bb70aac0394cc24 304 PRINTS PR00958 Homoserine kinase signature 130 143 2.5E-36 T 06-07-2017 GTHT12_RS15455 6af498ef3a3219208bb70aac0394cc24 304 Pfam PF00288 GHMP kinases N terminal domain 83 143 1.8E-14 T 06-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 GTHT12_RS15455 6af498ef3a3219208bb70aac0394cc24 304 Hamap MF_00384 Homoserine kinase [thrB]. 7 297 29.497 T 06-07-2017 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 GTHT12_RS15455 6af498ef3a3219208bb70aac0394cc24 304 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 89 100 - T 06-07-2017 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 GTHT12_RS07830 f02a9ab78765efea9cd4029ed638c748 307 Gene3D G3DSA:3.40.50.1100 38 135 8.6E-44 T 06-07-2017 GTHT12_RS07830 f02a9ab78765efea9cd4029ed638c748 307 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 06-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 GTHT12_RS07830 f02a9ab78765efea9cd4029ed638c748 307 SUPERFAMILY SSF53686 1 305 1.01E-101 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GTHT12_RS07830 f02a9ab78765efea9cd4029ed638c748 307 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 305 1.3E-119 T 06-07-2017 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 GTHT12_RS07830 f02a9ab78765efea9cd4029ed638c748 307 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 293 2.2E-69 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GTHT12_RS07830 f02a9ab78765efea9cd4029ed638c748 307 Gene3D G3DSA:3.40.50.1100 136 306 1.9E-70 T 06-07-2017 GTHT12_RS07830 f02a9ab78765efea9cd4029ed638c748 307 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 305 1.1E-124 T 06-07-2017 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 GTHT12_RS10390 4ba6f438e562c7694ccd82bebf5dd040 147 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 144 7.0E-36 T 06-07-2017 IPR002178 PTS EIIA type-2 domain GTHT12_RS10390 4ba6f438e562c7694ccd82bebf5dd040 147 SUPERFAMILY SSF55804 5 144 1.57E-41 T 06-07-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 GTHT12_RS10390 4ba6f438e562c7694ccd82bebf5dd040 147 Gene3D G3DSA:3.40.930.10 5 144 1.1E-44 T 06-07-2017 IPR002178 PTS EIIA type-2 domain GTHT12_RS10390 4ba6f438e562c7694ccd82bebf5dd040 147 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 50 66 - T 06-07-2017 IPR002178 PTS EIIA type-2 domain GTHT12_RS13135 60b0eabee8d02fee7d549ff82d4819f2 344 PIRSF PIRSF005485 1 341 3.5E-130 T 06-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 GTHT12_RS13135 60b0eabee8d02fee7d549ff82d4819f2 344 SUPERFAMILY SSF55781 71 341 7.06E-72 T 06-07-2017 IPR029016 GAF domain-like GTHT12_RS13135 60b0eabee8d02fee7d549ff82d4819f2 344 Gene3D G3DSA:3.30.450.40 176 342 3.1E-52 T 06-07-2017 IPR029016 GAF domain-like GTHT12_RS13135 60b0eabee8d02fee7d549ff82d4819f2 344 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 330 34.476 T 06-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 GTHT12_RS13135 60b0eabee8d02fee7d549ff82d4819f2 344 Gene3D G3DSA:1.10.10.10 2 83 5.7E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS13135 60b0eabee8d02fee7d549ff82d4819f2 344 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 336 1.7E-114 T 06-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 GTHT12_RS13135 60b0eabee8d02fee7d549ff82d4819f2 344 Pfam PF01628 HrcA protein C terminal domain 104 323 2.2E-68 T 06-07-2017 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 GTHT12_RS13135 60b0eabee8d02fee7d549ff82d4819f2 344 SUPERFAMILY SSF46785 2 84 6.6E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS08135 01a3e6201630c5d382d4b9f9d4784467 275 Gene3D G3DSA:3.30.1380.10 119 196 3.0E-7 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 GTHT12_RS08135 01a3e6201630c5d382d4b9f9d4784467 275 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 123 251 1.8E-46 T 06-07-2017 IPR003709 Peptidase M15B GO:0006508|GO:0008233 GTHT12_RS08135 01a3e6201630c5d382d4b9f9d4784467 275 SUPERFAMILY SSF55166 110 259 8.11E-40 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 GTHT12_RS17645 b0b1424b9a0343ed0539d3898766e79c 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 GTHT12_RS17645 b0b1424b9a0343ed0539d3898766e79c 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 GTHT12_RS17645 b0b1424b9a0343ed0539d3898766e79c 380 Gene3D G3DSA:2.40.110.10 121 218 2.7E-46 T 06-07-2017 GTHT12_RS17645 b0b1424b9a0343ed0539d3898766e79c 380 Gene3D G3DSA:1.10.540.10 1 119 9.8E-50 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS17645 b0b1424b9a0343ed0539d3898766e79c 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 2.1E-44 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS17645 b0b1424b9a0343ed0539d3898766e79c 380 Gene3D G3DSA:1.20.140.10 219 379 1.5E-76 T 06-07-2017 GTHT12_RS17645 b0b1424b9a0343ed0539d3898766e79c 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 4.4E-30 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 GTHT12_RS17645 b0b1424b9a0343ed0539d3898766e79c 380 SUPERFAMILY SSF56645 1 242 4.84E-100 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 GTHT12_RS17645 b0b1424b9a0343ed0539d3898766e79c 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 376 1.8E-53 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS17645 b0b1424b9a0343ed0539d3898766e79c 380 PIRSF PIRSF016578 3 378 3.3E-22 T 06-07-2017 GTHT12_RS17645 b0b1424b9a0343ed0539d3898766e79c 380 SUPERFAMILY SSF47203 227 379 2.42E-62 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS15760 873c1297b36cfa112f6842fd29e7bace 242 Pfam PF00005 ABC transporter 17 164 9.1E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS15760 873c1297b36cfa112f6842fd29e7bace 242 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS15760 873c1297b36cfa112f6842fd29e7bace 242 SMART SM00382 26 232 3.2E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS15760 873c1297b36cfa112f6842fd29e7bace 242 Gene3D G3DSA:3.40.50.300 2 234 7.9E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS15760 873c1297b36cfa112f6842fd29e7bace 242 SUPERFAMILY SSF52540 2 234 5.23E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10420 1de144d979d2ffb87c2972a5070d7890 395 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 171 199 - T 06-07-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 GTHT12_RS10420 1de144d979d2ffb87c2972a5070d7890 395 Pfam PF00465 Iron-containing alcohol dehydrogenase 7 376 2.3E-127 T 06-07-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 GTHT12_RS10420 1de144d979d2ffb87c2972a5070d7890 395 Gene3D G3DSA:3.40.50.1970 2 182 6.8E-60 T 06-07-2017 GTHT12_RS10420 1de144d979d2ffb87c2972a5070d7890 395 SUPERFAMILY SSF56796 3 384 5.23E-125 T 06-07-2017 GTHT12_RS10420 1de144d979d2ffb87c2972a5070d7890 395 Gene3D G3DSA:1.20.1090.10 183 384 1.1E-69 T 06-07-2017 GTHT12_RS09890 5fb9d2f3736a550dbfc553d6931e97e6 331 SUPERFAMILY SSF51445 5 330 2.62E-113 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS09890 5fb9d2f3736a550dbfc553d6931e97e6 331 Pfam PF00331 Glycosyl hydrolase family 10 7 330 1.7E-112 T 06-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 GTHT12_RS09890 5fb9d2f3736a550dbfc553d6931e97e6 331 SMART SM00633 47 330 3.2E-163 T 06-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 GTHT12_RS09890 5fb9d2f3736a550dbfc553d6931e97e6 331 PRINTS PR00134 Glycosyl hydrolase family 10 signature 172 183 1.7E-17 T 06-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 GTHT12_RS09890 5fb9d2f3736a550dbfc553d6931e97e6 331 PRINTS PR00134 Glycosyl hydrolase family 10 signature 200 212 1.7E-17 T 06-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 GTHT12_RS09890 5fb9d2f3736a550dbfc553d6931e97e6 331 PRINTS PR00134 Glycosyl hydrolase family 10 signature 78 90 1.7E-17 T 06-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 GTHT12_RS09890 5fb9d2f3736a550dbfc553d6931e97e6 331 PRINTS PR00134 Glycosyl hydrolase family 10 signature 126 137 1.7E-17 T 06-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 GTHT12_RS09890 5fb9d2f3736a550dbfc553d6931e97e6 331 Gene3D G3DSA:3.20.20.80 6 330 5.7E-114 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS05925 f167572b9c5f7747cdf54351bbb6da33 239 Pfam PF04542 Sigma-70 region 2 62 131 2.5E-18 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05925 f167572b9c5f7747cdf54351bbb6da33 239 Gene3D G3DSA:1.10.601.10 37 128 1.2E-32 T 06-07-2017 GTHT12_RS05925 f167572b9c5f7747cdf54351bbb6da33 239 PIRSF PIRSF000770 1 239 5.3E-76 T 06-07-2017 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 GTHT12_RS05925 f167572b9c5f7747cdf54351bbb6da33 239 TIGRFAM TIGR02835 spore_sigmaE: RNA polymerase sigma-E factor 8 239 1.5E-132 T 06-07-2017 IPR014200 RNA polymerase sigma-E type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05925 f167572b9c5f7747cdf54351bbb6da33 239 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 205 231 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05925 f167572b9c5f7747cdf54351bbb6da33 239 Gene3D G3DSA:1.10.10.10 176 235 2.9E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS05925 f167572b9c5f7747cdf54351bbb6da33 239 Pfam PF04545 Sigma-70, region 4 180 233 2.5E-16 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05925 f167572b9c5f7747cdf54351bbb6da33 239 SUPERFAMILY SSF88659 143 237 3.55E-21 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05925 f167572b9c5f7747cdf54351bbb6da33 239 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 58 234 9.7E-37 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05925 f167572b9c5f7747cdf54351bbb6da33 239 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 86 99 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05925 f167572b9c5f7747cdf54351bbb6da33 239 SUPERFAMILY SSF88946 25 131 3.45E-35 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05925 f167572b9c5f7747cdf54351bbb6da33 239 PRINTS PR00046 Major sigma-70 factor signature 86 99 1.0E-11 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05925 f167572b9c5f7747cdf54351bbb6da33 239 PRINTS PR00046 Major sigma-70 factor signature 184 196 1.0E-11 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05925 f167572b9c5f7747cdf54351bbb6da33 239 PRINTS PR00046 Major sigma-70 factor signature 220 231 1.0E-11 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05925 f167572b9c5f7747cdf54351bbb6da33 239 PRINTS PR00046 Major sigma-70 factor signature 205 220 1.0E-11 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS03800 12f7691445d746820129e99d8c3d68d8 1114 Pfam PF13558 Putative exonuclease SbcCD, C subunit 985 1069 1.3E-15 T 06-07-2017 GTHT12_RS03800 12f7691445d746820129e99d8c3d68d8 1114 Gene3D G3DSA:3.40.50.300 4 160 1.4E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03800 12f7691445d746820129e99d8c3d68d8 1114 Gene3D G3DSA:1.10.287.510 485 587 7.6E-4 T 06-07-2017 GTHT12_RS03800 12f7691445d746820129e99d8c3d68d8 1114 SUPERFAMILY SSF75712 491 578 9.81E-5 T 06-07-2017 GTHT12_RS03800 12f7691445d746820129e99d8c3d68d8 1114 SUPERFAMILY SSF52540 1004 1097 1.55E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03800 12f7691445d746820129e99d8c3d68d8 1114 SUPERFAMILY SSF52540 19 186 1.55E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03800 12f7691445d746820129e99d8c3d68d8 1114 Gene3D G3DSA:3.40.50.300 939 1095 9.3E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03800 12f7691445d746820129e99d8c3d68d8 1114 Pfam PF13476 AAA domain 5 241 2.8E-10 T 06-07-2017 GTHT12_RS01555 f90561e31529559b5eb9fdef069a8b7e 34 SUPERFAMILY SSF54810 2 34 3.01E-10 T 06-07-2017 GTHT12_RS01555 f90561e31529559b5eb9fdef069a8b7e 34 Gene3D G3DSA:3.30.300.10 2 34 2.2E-9 T 06-07-2017 GTHT12_RS01555 f90561e31529559b5eb9fdef069a8b7e 34 Pfam PF00958 GMP synthase C terminal domain 1 33 8.7E-10 T 06-07-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 GTHT12_RS15705 bb717116de49d092f352b47cb7be089b 355 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 4 355 3.7E-73 T 06-07-2017 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 GTHT12_RS15705 bb717116de49d092f352b47cb7be089b 355 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 195 352 6.0E-20 T 06-07-2017 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 GTHT12_RS18825 fe8a2c3a90051368c6840e02aee622c4 295 Gene3D G3DSA:3.40.50.300 3 220 3.5E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18825 fe8a2c3a90051368c6840e02aee622c4 295 Pfam PF00005 ABC transporter 21 161 6.2E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS18825 fe8a2c3a90051368c6840e02aee622c4 295 SUPERFAMILY SSF52540 4 220 1.98E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18825 fe8a2c3a90051368c6840e02aee622c4 295 SMART SM00382 26 210 6.1E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS03925 1043baa7ce87e56b4bc6cf612b509138 641 SUPERFAMILY SSF55781 58 192 6.38E-10 T 06-07-2017 IPR029016 GAF domain-like GTHT12_RS03925 1043baa7ce87e56b4bc6cf612b509138 641 SMART SM00382 354 498 9.6E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS03925 1043baa7ce87e56b4bc6cf612b509138 641 Gene3D G3DSA:1.10.8.60 508 582 9.2E-26 T 06-07-2017 GTHT12_RS03925 1043baa7ce87e56b4bc6cf612b509138 641 SUPERFAMILY SSF52540 333 579 1.08E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03925 1043baa7ce87e56b4bc6cf612b509138 641 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 421 436 - T 06-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 GTHT12_RS03925 1043baa7ce87e56b4bc6cf612b509138 641 Gene3D G3DSA:3.30.450.20 208 311 1.1E-7 T 06-07-2017 GTHT12_RS03925 1043baa7ce87e56b4bc6cf612b509138 641 SUPERFAMILY SSF46689 548 639 1.14E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS03925 1043baa7ce87e56b4bc6cf612b509138 641 Gene3D G3DSA:3.30.450.40 150 198 1.5E-5 T 06-07-2017 IPR029016 GAF domain-like GTHT12_RS03925 1043baa7ce87e56b4bc6cf612b509138 641 Gene3D G3DSA:1.10.10.60 601 636 1.4E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS03925 1043baa7ce87e56b4bc6cf612b509138 641 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 358 371 - T 06-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 GTHT12_RS03925 1043baa7ce87e56b4bc6cf612b509138 641 Gene3D G3DSA:3.40.50.300 331 507 4.1E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03925 1043baa7ce87e56b4bc6cf612b509138 641 SMART SM00091 209 275 0.0078 T 06-07-2017 IPR000014 PAS domain GTHT12_RS03925 1043baa7ce87e56b4bc6cf612b509138 641 Pfam PF02954 Bacterial regulatory protein, Fis family 602 637 1.1E-13 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GTHT12_RS03925 1043baa7ce87e56b4bc6cf612b509138 641 Pfam PF00158 Sigma-54 interaction domain 334 501 2.8E-68 T 06-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 GTHT12_RS03925 1043baa7ce87e56b4bc6cf612b509138 641 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 548 557 - T 06-07-2017 IPR025944 Sigma-54 interaction domain, conserved site GTHT12_RS03925 1043baa7ce87e56b4bc6cf612b509138 641 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 620 640 6.5E-10 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GTHT12_RS03925 1043baa7ce87e56b4bc6cf612b509138 641 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 603 620 6.5E-10 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GTHT12_RS05740 2fc317bac1a24e371233d9616c49f84a 335 SUPERFAMILY SSF55797 214 332 7.85E-21 T 06-07-2017 IPR014044 CAP domain GTHT12_RS05740 2fc317bac1a24e371233d9616c49f84a 335 Pfam PF00188 Cysteine-rich secretory protein family 222 330 1.1E-16 T 06-07-2017 IPR014044 CAP domain GTHT12_RS05740 2fc317bac1a24e371233d9616c49f84a 335 Gene3D G3DSA:3.40.33.10 211 322 4.4E-10 T 06-07-2017 IPR014044 CAP domain GTHT12_RS05740 2fc317bac1a24e371233d9616c49f84a 335 Pfam PF14504 CAP-associated N-terminal 50 189 1.8E-47 T 06-07-2017 IPR029410 CAP-associated domain GTHT12_RS05760 6a89e032c983432c23e2f47fdd1e9162 148 Gene3D G3DSA:1.20.1500.10 4 127 1.0E-33 T 06-07-2017 IPR023378 YheA/YmcA-like domain GTHT12_RS05760 6a89e032c983432c23e2f47fdd1e9162 148 SUPERFAMILY SSF158622 5 127 2.62E-37 T 06-07-2017 IPR023378 YheA/YmcA-like domain GTHT12_RS05760 6a89e032c983432c23e2f47fdd1e9162 148 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 11 117 3.7E-23 T 06-07-2017 IPR010368 Control of competence regulator ComK, YlbF/YmcA GTHT12_RS13380 aa5c0867b3f7254c9a203ad1f6fa7cd4 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 300 313 4.8E-32 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 GTHT12_RS13380 aa5c0867b3f7254c9a203ad1f6fa7cd4 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 4.8E-32 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 GTHT12_RS13380 aa5c0867b3f7254c9a203ad1f6fa7cd4 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 4.8E-32 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 GTHT12_RS13380 aa5c0867b3f7254c9a203ad1f6fa7cd4 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 4.8E-32 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 GTHT12_RS13380 aa5c0867b3f7254c9a203ad1f6fa7cd4 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 276 292 4.8E-32 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 GTHT12_RS13380 aa5c0867b3f7254c9a203ad1f6fa7cd4 878 Gene3D G3DSA:3.30.930.10 4 241 3.8E-99 T 06-07-2017 GTHT12_RS13380 aa5c0867b3f7254c9a203ad1f6fa7cd4 878 Pfam PF01411 tRNA synthetases class II (A) 8 556 1.2E-214 T 06-07-2017 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 GTHT12_RS13380 aa5c0867b3f7254c9a203ad1f6fa7cd4 878 SUPERFAMILY SSF50447 456 554 7.42E-17 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain GTHT12_RS13380 aa5c0867b3f7254c9a203ad1f6fa7cd4 878 SMART SM00863 655 698 2.0E-21 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 GTHT12_RS13380 aa5c0867b3f7254c9a203ad1f6fa7cd4 878 SUPERFAMILY SSF55681 5 245 3.48E-90 T 06-07-2017 GTHT12_RS13380 aa5c0867b3f7254c9a203ad1f6fa7cd4 878 SUPERFAMILY SSF101353 246 438 9.15E-70 T 06-07-2017 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 GTHT12_RS13380 aa5c0867b3f7254c9a203ad1f6fa7cd4 878 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 655 698 1.8E-18 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 GTHT12_RS13380 aa5c0867b3f7254c9a203ad1f6fa7cd4 878 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 857 0.0 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 GTHT12_RS13380 aa5c0867b3f7254c9a203ad1f6fa7cd4 878 SUPERFAMILY SSF55186 554 720 4.84E-54 T 06-07-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 GTHT12_RS13380 aa5c0867b3f7254c9a203ad1f6fa7cd4 878 Pfam PF02272 DHHA1 domain 802 871 1.4E-18 T 06-07-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 GTHT12_RS13380 aa5c0867b3f7254c9a203ad1f6fa7cd4 878 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 878 188.533 T 06-07-2017 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 GTHT12_RS08225 1367415a100fddf4ee2080f5e8ed4ad7 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 GTHT12_RS08225 1367415a100fddf4ee2080f5e8ed4ad7 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 GTHT12_RS08225 1367415a100fddf4ee2080f5e8ed4ad7 380 PIRSF PIRSF016578 3 378 5.2E-25 T 06-07-2017 GTHT12_RS08225 1367415a100fddf4ee2080f5e8ed4ad7 380 Gene3D G3DSA:1.10.540.10 1 119 1.0E-48 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS08225 1367415a100fddf4ee2080f5e8ed4ad7 380 Gene3D G3DSA:2.40.110.10 121 218 8.8E-42 T 06-07-2017 GTHT12_RS08225 1367415a100fddf4ee2080f5e8ed4ad7 380 SUPERFAMILY SSF56645 1 243 1.96E-91 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 GTHT12_RS08225 1367415a100fddf4ee2080f5e8ed4ad7 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 378 2.5E-54 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS08225 1367415a100fddf4ee2080f5e8ed4ad7 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 218 5.1E-28 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 GTHT12_RS08225 1367415a100fddf4ee2080f5e8ed4ad7 380 Gene3D G3DSA:1.20.140.10 219 378 4.1E-76 T 06-07-2017 GTHT12_RS08225 1367415a100fddf4ee2080f5e8ed4ad7 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 3.0E-42 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS08225 1367415a100fddf4ee2080f5e8ed4ad7 380 SUPERFAMILY SSF47203 229 378 3.14E-62 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS15945 ce5953c049d1743ac97f883e3981b3d8 298 Pfam PF03668 P-loop ATPase protein family 11 293 4.2E-127 T 06-07-2017 IPR005337 RapZ-like family GO:0005524 GTHT12_RS15945 ce5953c049d1743ac97f883e3981b3d8 298 Gene3D G3DSA:3.40.50.300 8 165 1.0E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS15945 ce5953c049d1743ac97f883e3981b3d8 298 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 10 292 42.428 T 06-07-2017 IPR005337 RapZ-like family GO:0005524 GTHT12_RS15945 ce5953c049d1743ac97f883e3981b3d8 298 PIRSF PIRSF005052 10 295 1.5E-108 T 06-07-2017 IPR005337 RapZ-like family GO:0005524 GTHT12_RS15945 ce5953c049d1743ac97f883e3981b3d8 298 SUPERFAMILY SSF52540 12 162 4.61E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10940 5e02141e48eb9bb5df8d682ab6d0a82b 189 Gene3D G3DSA:3.30.110.40 2 75 5.4E-32 T 06-07-2017 IPR001455 TusA-like domain GTHT12_RS10940 5e02141e48eb9bb5df8d682ab6d0a82b 189 Pfam PF00581 Rhodanese-like domain 92 181 2.1E-17 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS10940 5e02141e48eb9bb5df8d682ab6d0a82b 189 Gene3D G3DSA:3.40.250.10 86 181 1.2E-31 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS10940 5e02141e48eb9bb5df8d682ab6d0a82b 189 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 8 32 - T 06-07-2017 IPR001455 TusA-like domain GTHT12_RS10940 5e02141e48eb9bb5df8d682ab6d0a82b 189 ProSitePatterns PS00380 Rhodanese signature 1. 116 127 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 GTHT12_RS10940 5e02141e48eb9bb5df8d682ab6d0a82b 189 SMART SM00450 91 186 4.2E-25 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS10940 5e02141e48eb9bb5df8d682ab6d0a82b 189 SUPERFAMILY SSF64307 2 75 1.26E-24 T 06-07-2017 IPR001455 TusA-like domain GTHT12_RS10940 5e02141e48eb9bb5df8d682ab6d0a82b 189 Pfam PF01206 Sulfurtransferase TusA 7 75 1.7E-21 T 06-07-2017 IPR001455 TusA-like domain GTHT12_RS10940 5e02141e48eb9bb5df8d682ab6d0a82b 189 SUPERFAMILY SSF52821 89 181 1.15E-32 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS13525 a24ce61942b031ad51d310c3c558164f 380 Gene3D G3DSA:3.20.20.105 4 371 4.5E-168 T 06-07-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 GTHT12_RS13525 a24ce61942b031ad51d310c3c558164f 380 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 7 374 2.1E-173 T 06-07-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 GTHT12_RS13525 a24ce61942b031ad51d310c3c558164f 380 Pfam PF01702 Queuine tRNA-ribosyltransferase 134 366 3.7E-92 T 06-07-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 GTHT12_RS13525 a24ce61942b031ad51d310c3c558164f 380 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 7 374 9.6E-184 T 06-07-2017 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 GTHT12_RS13525 a24ce61942b031ad51d310c3c558164f 380 SUPERFAMILY SSF51713 5 370 9.29E-162 T 06-07-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 GTHT12_RS13525 a24ce61942b031ad51d310c3c558164f 380 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 5 364 58.029 T 06-07-2017 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 GTHT12_RS00425 2b5f1ec659b1ee6e5e65aaa1198d4a86 175 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 6 133 1.7E-40 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 GTHT12_RS00425 2b5f1ec659b1ee6e5e65aaa1198d4a86 175 SUPERFAMILY SSF55083 4 157 1.12E-56 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 GTHT12_RS00425 2b5f1ec659b1ee6e5e65aaa1198d4a86 175 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 89 100 - T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 GTHT12_RS00425 2b5f1ec659b1ee6e5e65aaa1198d4a86 175 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 133 1.2E-48 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 GTHT12_RS00425 2b5f1ec659b1ee6e5e65aaa1198d4a86 175 Gene3D G3DSA:3.30.70.560 4 156 1.5E-58 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 GTHT12_RS14770 ca6e44614ec48ad7eebec16a260526f6 360 Pfam PF10776 Protein of unknown function (DUF2600) 20 348 7.1E-153 T 06-07-2017 IPR019712 Protein of unknown function DUF2600 KEGG: 00909+4.2.3.13|MetaCyc: PWY-5773|MetaCyc: PWY-5828 GTHT12_RS05940 6d6297aa50b0f2b87899698b68281d17 274 Gene3D G3DSA:3.60.140.10 7 273 2.4E-90 T 06-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase GTHT12_RS05940 6d6297aa50b0f2b87899698b68281d17 274 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 28 267 3.9E-76 T 06-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase GTHT12_RS05940 6d6297aa50b0f2b87899698b68281d17 274 SUPERFAMILY SSF64438 4 270 3.66E-86 T 06-07-2017 IPR011324 Cytotoxic necrotizing factor-like, catalytic GTHT12_RS05940 6d6297aa50b0f2b87899698b68281d17 274 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 35 268 2.5E-62 T 06-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase GTHT12_RS01055 ffa7e8c066d1df356c53ccb9f42bcf08 545 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 259 275 2.6E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 GTHT12_RS01055 ffa7e8c066d1df356c53ccb9f42bcf08 545 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 244 259 2.6E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 GTHT12_RS01055 ffa7e8c066d1df356c53ccb9f42bcf08 545 SUPERFAMILY SSF46689 228 280 1.97E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS01055 ffa7e8c066d1df356c53ccb9f42bcf08 545 Gene3D G3DSA:3.40.50.1980 385 539 8.5E-27 T 06-07-2017 GTHT12_RS01055 ffa7e8c066d1df356c53ccb9f42bcf08 545 SUPERFAMILY SSF46689 178 226 1.36E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS01055 ffa7e8c066d1df356c53ccb9f42bcf08 545 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 229 271 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 GTHT12_RS01055 ffa7e8c066d1df356c53ccb9f42bcf08 545 SUPERFAMILY SSF53807 274 532 7.85E-36 T 06-07-2017 GTHT12_RS01055 ffa7e8c066d1df356c53ccb9f42bcf08 545 SMART SM00342 192 275 5.7E-32 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 GTHT12_RS01055 ffa7e8c066d1df356c53ccb9f42bcf08 545 Gene3D G3DSA:3.40.50.1980 271 384 1.0E-8 T 06-07-2017 GTHT12_RS01055 ffa7e8c066d1df356c53ccb9f42bcf08 545 SUPERFAMILY SSF51215 31 166 3.79E-8 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 GTHT12_RS01055 ffa7e8c066d1df356c53ccb9f42bcf08 545 Pfam PF01497 Periplasmic binding protein 282 518 5.3E-19 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 GTHT12_RS01055 ffa7e8c066d1df356c53ccb9f42bcf08 545 Gene3D G3DSA:2.60.120.280 32 166 3.6E-6 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 GTHT12_RS01055 ffa7e8c066d1df356c53ccb9f42bcf08 545 Gene3D G3DSA:1.10.10.60 229 270 2.2E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS01055 ffa7e8c066d1df356c53ccb9f42bcf08 545 Pfam PF02311 AraC-like ligand binding domain 34 119 1.8E-5 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 GTHT12_RS01055 ffa7e8c066d1df356c53ccb9f42bcf08 545 Pfam PF12833 Helix-turn-helix domain 198 276 7.3E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 GTHT12_RS01055 ffa7e8c066d1df356c53ccb9f42bcf08 545 Gene3D G3DSA:1.10.10.60 171 228 9.9E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS12200 ff42c4209ad4bcc91fae36769b15fd6e 433 SMART SM00941 345 418 6.2E-34 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 GTHT12_RS12200 ff42c4209ad4bcc91fae36769b15fd6e 433 PIRSF PIRSF000478 1 433 3.9E-174 T 06-07-2017 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 GTHT12_RS12200 ff42c4209ad4bcc91fae36769b15fd6e 433 Pfam PF00591 Glycosyl transferase family, a/b domain 78 305 1.7E-48 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 GTHT12_RS12200 ff42c4209ad4bcc91fae36769b15fd6e 433 Gene3D G3DSA:1.20.970.10 1 67 2.9E-36 T 06-07-2017 GTHT12_RS12200 ff42c4209ad4bcc91fae36769b15fd6e 433 SUPERFAMILY SSF47648 1 69 1.7E-25 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 GTHT12_RS12200 ff42c4209ad4bcc91fae36769b15fd6e 433 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 417 2.2E-185 T 06-07-2017 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 GTHT12_RS12200 ff42c4209ad4bcc91fae36769b15fd6e 433 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 6.3E-26 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 GTHT12_RS12200 ff42c4209ad4bcc91fae36769b15fd6e 433 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 418 1.9E-27 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 GTHT12_RS12200 ff42c4209ad4bcc91fae36769b15fd6e 433 SUPERFAMILY SSF52418 69 329 1.7E-93 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 GTHT12_RS12200 ff42c4209ad4bcc91fae36769b15fd6e 433 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 06-07-2017 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 GTHT12_RS12200 ff42c4209ad4bcc91fae36769b15fd6e 433 Gene3D G3DSA:3.90.1170.30 335 422 2.1E-33 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 GTHT12_RS12200 ff42c4209ad4bcc91fae36769b15fd6e 433 SUPERFAMILY SSF54680 331 432 2.62E-32 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 GTHT12_RS12200 ff42c4209ad4bcc91fae36769b15fd6e 433 Gene3D G3DSA:3.40.1030.10 70 334 7.9E-119 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 GTHT12_RS08250 e710814665c0f87d8b19f5a2a76d85bb 260 Gene3D G3DSA:3.90.226.10 10 202 9.3E-76 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS08250 e710814665c0f87d8b19f5a2a76d85bb 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 259 2.8E-73 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 GTHT12_RS08250 e710814665c0f87d8b19f5a2a76d85bb 260 SUPERFAMILY SSF52096 5 259 3.22E-87 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS08250 e710814665c0f87d8b19f5a2a76d85bb 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 GTHT12_RS08250 e710814665c0f87d8b19f5a2a76d85bb 260 Gene3D G3DSA:1.10.12.10 203 260 9.9E-21 T 06-07-2017 IPR014748 Crontonase, C-terminal GTHT12_RS14025 62721268f5edb74c6547524feb4557b4 557 Gene3D G3DSA:3.30.300.30 456 555 1.4E-36 T 06-07-2017 GTHT12_RS14025 62721268f5edb74c6547524feb4557b4 557 Pfam PF13193 AMP-binding enzyme C-terminal domain 468 543 7.4E-24 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain GTHT12_RS14025 62721268f5edb74c6547524feb4557b4 557 Gene3D G3DSA:3.40.50.980 22 135 9.2E-41 T 06-07-2017 GTHT12_RS14025 62721268f5edb74c6547524feb4557b4 557 Gene3D G3DSA:3.40.50.980 195 219 9.2E-41 T 06-07-2017 GTHT12_RS14025 62721268f5edb74c6547524feb4557b4 557 ProSitePatterns PS00455 Putative AMP-binding domain signature. 210 221 - T 06-07-2017 IPR020845 AMP-binding, conserved site GTHT12_RS14025 62721268f5edb74c6547524feb4557b4 557 Gene3D G3DSA:3.40.50.980 220 368 9.2E-46 T 06-07-2017 GTHT12_RS14025 62721268f5edb74c6547524feb4557b4 557 Pfam PF00501 AMP-binding enzyme 29 458 8.0E-118 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GTHT12_RS14025 62721268f5edb74c6547524feb4557b4 557 Gene3D G3DSA:2.30.38.10 376 450 1.1E-31 T 06-07-2017 GTHT12_RS14025 62721268f5edb74c6547524feb4557b4 557 SUPERFAMILY SSF56801 7 553 2.22E-167 T 06-07-2017 GTHT12_RS14380 7d3735e87d3bbe9b9c52c053162ebf14 159 PIRSF PIRSF021377 1 158 2.2E-65 T 06-07-2017 IPR014229 Sporulation protein YtfJ GTHT12_RS14380 7d3735e87d3bbe9b9c52c053162ebf14 159 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 3 145 2.0E-52 T 06-07-2017 IPR014229 Sporulation protein YtfJ GTHT12_RS14380 7d3735e87d3bbe9b9c52c053162ebf14 159 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 31 134 5.2E-27 T 06-07-2017 IPR014229 Sporulation protein YtfJ GTHT12_RS13480 b87e977025163c582349553e67f6c9d6 732 SUPERFAMILY SSF81271 380 452 3.76E-24 T 06-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 GTHT12_RS13480 b87e977025163c582349553e67f6c9d6 732 Pfam PF04607 Region found in RelA / SpoT proteins 240 350 2.0E-40 T 06-07-2017 IPR007685 RelA/SpoT GO:0015969 GTHT12_RS13480 b87e977025163c582349553e67f6c9d6 732 SUPERFAMILY SSF55021 652 731 3.85E-12 T 06-07-2017 GTHT12_RS13480 b87e977025163c582349553e67f6c9d6 732 Gene3D G3DSA:3.30.70.260 653 726 3.4E-12 T 06-07-2017 GTHT12_RS13480 b87e977025163c582349553e67f6c9d6 732 SMART SM00471 46 158 7.5E-10 T 06-07-2017 IPR003607 HD/PDEase domain GTHT12_RS13480 b87e977025163c582349553e67f6c9d6 732 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 31 728 7.9E-266 T 06-07-2017 IPR004811 RelA/SpoT family GO:0015969 GTHT12_RS13480 b87e977025163c582349553e67f6c9d6 732 Pfam PF02824 TGS domain 393 452 2.2E-24 T 06-07-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 GTHT12_RS13480 b87e977025163c582349553e67f6c9d6 732 Pfam PF13328 HD domain 31 180 2.9E-54 T 06-07-2017 IPR003607 HD/PDEase domain GTHT12_RS13480 b87e977025163c582349553e67f6c9d6 732 SUPERFAMILY SSF81301 185 397 1.24E-70 T 06-07-2017 GTHT12_RS13480 b87e977025163c582349553e67f6c9d6 732 Gene3D G3DSA:3.30.460.10 183 330 2.0E-52 T 06-07-2017 GTHT12_RS13480 b87e977025163c582349553e67f6c9d6 732 SMART SM00954 240 350 1.3E-70 T 06-07-2017 IPR007685 RelA/SpoT GO:0015969 GTHT12_RS13480 b87e977025163c582349553e67f6c9d6 732 SUPERFAMILY SSF109604 11 196 3.45E-79 T 06-07-2017 GTHT12_RS13480 b87e977025163c582349553e67f6c9d6 732 Gene3D G3DSA:3.10.20.30 392 455 1.7E-25 T 06-07-2017 IPR012675 Beta-grasp domain GTHT12_RS13480 b87e977025163c582349553e67f6c9d6 732 Pfam PF13291 ACT domain 650 728 7.5E-22 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 GTHT12_RS01465 36c05e6bbbd681ba0a0240529c2a7971 247 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 2 238 18.062 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 GTHT12_RS01465 36c05e6bbbd681ba0a0240529c2a7971 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 81 99 2.9E-41 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 GTHT12_RS01465 36c05e6bbbd681ba0a0240529c2a7971 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 7 34 2.9E-41 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 GTHT12_RS01465 36c05e6bbbd681ba0a0240529c2a7971 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 151 179 2.9E-41 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 GTHT12_RS01465 36c05e6bbbd681ba0a0240529c2a7971 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 99 125 2.9E-41 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 GTHT12_RS01465 36c05e6bbbd681ba0a0240529c2a7971 247 Pfam PF00902 Sec-independent protein translocase protein (TatC) 10 218 9.3E-62 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 GTHT12_RS01465 36c05e6bbbd681ba0a0240529c2a7971 247 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 9 223 3.4E-68 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 GTHT12_RS01465 36c05e6bbbd681ba0a0240529c2a7971 247 ProSitePatterns PS01218 TatC family signature. 151 170 - T 06-07-2017 IPR019820 Sec-independent periplasmic protein translocase, conserved site GTHT12_RS08065 ac640b38f6b240b88bc4248b103d24dd 135 Gene3D G3DSA:3.10.129.10 3 134 1.8E-54 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS08065 ac640b38f6b240b88bc4248b103d24dd 135 SUPERFAMILY SSF54637 10 134 2.33E-36 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS08065 ac640b38f6b240b88bc4248b103d24dd 135 Pfam PF03061 Thioesterase superfamily 46 123 4.2E-19 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 GTHT12_RS08065 ac640b38f6b240b88bc4248b103d24dd 135 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 15 130 1.1E-40 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 GTHT12_RS10605 5fc9ed4024573bc8b15f5f320f23d2e8 149 Gene3D G3DSA:3.10.129.10 2 134 1.1E-40 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS10605 5fc9ed4024573bc8b15f5f320f23d2e8 149 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 8 101 3.5E-21 T 06-07-2017 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 GTHT12_RS10605 5fc9ed4024573bc8b15f5f320f23d2e8 149 Pfam PF03061 Thioesterase superfamily 19 102 5.0E-15 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 GTHT12_RS10605 5fc9ed4024573bc8b15f5f320f23d2e8 149 SUPERFAMILY SSF54637 3 134 3.02E-35 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS09655 affb74464832bfb2a8594ac63a6a3325 220 SUPERFAMILY SSF52540 1 204 1.6E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS09655 affb74464832bfb2a8594ac63a6a3325 220 Gene3D G3DSA:3.40.50.300 1 205 1.2E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS09655 affb74464832bfb2a8594ac63a6a3325 220 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS09655 affb74464832bfb2a8594ac63a6a3325 220 SMART SM00382 26 202 5.1E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS09655 affb74464832bfb2a8594ac63a6a3325 220 Pfam PF00005 ABC transporter 17 156 1.2E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS00375 d92ccdb5aecdf7a88301a0397cebcd08 181 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 10 175 3.8E-67 T 06-07-2017 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 GTHT12_RS00375 d92ccdb5aecdf7a88301a0397cebcd08 181 Gene3D G3DSA:3.40.50.2020 2 181 2.6E-83 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS00375 d92ccdb5aecdf7a88301a0397cebcd08 181 Pfam PF00156 Phosphoribosyl transferase domain 16 161 1.0E-22 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 GTHT12_RS00375 d92ccdb5aecdf7a88301a0397cebcd08 181 SUPERFAMILY SSF53271 2 179 1.57E-59 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS16195 fcd15607cf19d08dd2896a44c3a1c6cb 37 Pfam PF00700 Bacterial flagellin C-terminal helical region 1 36 3.9E-8 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 GTHT12_RS16195 fcd15607cf19d08dd2896a44c3a1c6cb 37 SUPERFAMILY SSF64518 1 37 1.44E-9 T 06-07-2017 GTHT12_RS10180 667e4446115a1e4b553d924cf447b4ad 403 SMART SM00342 317 400 4.1E-28 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 GTHT12_RS10180 667e4446115a1e4b553d924cf447b4ad 403 Pfam PF00072 Response regulator receiver domain 4 116 2.9E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS10180 667e4446115a1e4b553d924cf447b4ad 403 SUPERFAMILY SSF46689 301 350 2.15E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS10180 667e4446115a1e4b553d924cf447b4ad 403 SUPERFAMILY SSF46689 353 402 2.73E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS10180 667e4446115a1e4b553d924cf447b4ad 403 SUPERFAMILY SSF52172 1 132 2.28E-34 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS10180 667e4446115a1e4b553d924cf447b4ad 403 SMART SM00448 2 116 2.1E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS10180 667e4446115a1e4b553d924cf447b4ad 403 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 354 396 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 GTHT12_RS10180 667e4446115a1e4b553d924cf447b4ad 403 Gene3D G3DSA:1.10.10.60 354 402 1.8E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS10180 667e4446115a1e4b553d924cf447b4ad 403 Gene3D G3DSA:1.10.10.60 297 353 1.1E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS10180 667e4446115a1e4b553d924cf447b4ad 403 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 384 400 2.5E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 GTHT12_RS10180 667e4446115a1e4b553d924cf447b4ad 403 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 369 384 2.5E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 GTHT12_RS10180 667e4446115a1e4b553d924cf447b4ad 403 Gene3D G3DSA:3.40.50.2300 1 133 2.6E-35 T 06-07-2017 GTHT12_RS10180 667e4446115a1e4b553d924cf447b4ad 403 Pfam PF12833 Helix-turn-helix domain 323 401 2.1E-17 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 GTHT12_RS12860 2bf9eb94464b3f31819533786c6afe14 189 PIRSF PIRSF006806 1 184 1.4E-53 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase GTHT12_RS12860 2bf9eb94464b3f31819533786c6afe14 189 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 4 180 7.8E-58 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase GTHT12_RS12860 2bf9eb94464b3f31819533786c6afe14 189 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 4 180 1.4E-47 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase GTHT12_RS12860 2bf9eb94464b3f31819533786c6afe14 189 SUPERFAMILY SSF100950 4 188 1.16E-54 T 06-07-2017 GTHT12_RS12860 2bf9eb94464b3f31819533786c6afe14 189 Gene3D G3DSA:3.40.50.10420 4 187 6.5E-60 T 06-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain GTHT12_RS07790 0cd13cc0b75cc893ffa1004712fb156d 56 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 56 15.713 T 06-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 GTHT12_RS07790 0cd13cc0b75cc893ffa1004712fb156d 56 Pfam PF02416 mttA/Hcf106 family 3 53 7.1E-21 T 06-07-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 GTHT12_RS07790 0cd13cc0b75cc893ffa1004712fb156d 56 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 45 9.9E-17 T 06-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 GTHT12_RS17035 87889dab5f105125a25553fe75bb01dc 428 Gene3D G3DSA:3.40.190.10 167 361 6.4E-37 T 06-07-2017 GTHT12_RS17035 87889dab5f105125a25553fe75bb01dc 428 Pfam PF13416 Bacterial extracellular solute-binding protein 57 366 5.8E-39 T 06-07-2017 GTHT12_RS17035 87889dab5f105125a25553fe75bb01dc 428 Gene3D G3DSA:3.40.190.10 37 166 8.4E-22 T 06-07-2017 GTHT12_RS17035 87889dab5f105125a25553fe75bb01dc 428 SUPERFAMILY SSF53850 18 427 6.92E-75 T 06-07-2017 GTHT12_RS08230 b5099ac2ee50232a93bd689b03c847c9 544 SUPERFAMILY SSF56801 4 538 2.88E-167 T 06-07-2017 GTHT12_RS08230 b5099ac2ee50232a93bd689b03c847c9 544 Gene3D G3DSA:3.40.50.980 207 351 4.5E-55 T 06-07-2017 GTHT12_RS08230 b5099ac2ee50232a93bd689b03c847c9 544 Pfam PF00501 AMP-binding enzyme 10 442 1.3E-115 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GTHT12_RS08230 b5099ac2ee50232a93bd689b03c847c9 544 Gene3D G3DSA:3.30.300.30 439 539 1.9E-37 T 06-07-2017 GTHT12_RS08230 b5099ac2ee50232a93bd689b03c847c9 544 ProSitePatterns PS00455 Putative AMP-binding domain signature. 192 203 - T 06-07-2017 IPR020845 AMP-binding, conserved site GTHT12_RS08230 b5099ac2ee50232a93bd689b03c847c9 544 Gene3D G3DSA:3.40.50.980 5 206 3.8E-42 T 06-07-2017 GTHT12_RS08230 b5099ac2ee50232a93bd689b03c847c9 544 Gene3D G3DSA:2.30.38.10 359 433 1.2E-31 T 06-07-2017 GTHT12_RS08230 b5099ac2ee50232a93bd689b03c847c9 544 Pfam PF13193 AMP-binding enzyme C-terminal domain 451 526 4.7E-19 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 Gene3D G3DSA:3.90.1440.10 228 348 1.5E-49 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 ProSitePatterns PS01312 SecA family signature. 480 495 - T 06-07-2017 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 496 2.3E-247 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 Pfam PF07517 SecA DEAD-like domain 6 382 5.0E-131 T 06-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 SMART SM00958 226 338 9.5E-69 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 SMART SM00957 5 382 1.1E-289 T 06-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 SUPERFAMILY SSF52540 396 569 4.04E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 Pfam PF07516 SecA Wing and Scaffold domain 568 778 5.9E-67 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 SUPERFAMILY SSF52540 6 226 7.67E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 SUPERFAMILY SSF52540 348 395 7.67E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 SUPERFAMILY SSF81886 571 825 6.02E-84 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 SUPERFAMILY SSF81767 225 348 4.32E-48 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 Gene3D G3DSA:1.10.3060.10 599 780 1.3E-57 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 Pfam PF01043 SecA preprotein cross-linking domain 230 338 2.5E-42 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 Gene3D G3DSA:3.40.50.300 6 226 1.6E-122 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 Gene3D G3DSA:3.40.50.300 349 396 1.6E-122 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 781 20.028 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 Pfam PF02810 SEC-C motif 817 835 2.8E-10 T 06-07-2017 IPR004027 SEC-C motif GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 PRINTS PR00906 SecA protein signature 168 188 2.2E-71 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 PRINTS PR00906 SecA protein signature 115 125 2.2E-71 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 PRINTS PR00906 SecA protein signature 61 85 2.2E-71 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 PRINTS PR00906 SecA protein signature 319 341 2.2E-71 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 PRINTS PR00906 SecA protein signature 393 406 2.2E-71 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 PRINTS PR00906 SecA protein signature 356 373 2.2E-71 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 PRINTS PR00906 SecA protein signature 99 113 2.2E-71 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 GTHT12_RS16115 7f67b9cedc8a9627832f068cab416564 837 Gene3D G3DSA:3.40.50.300 397 570 2.1E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS14440 06e0005a3a3759e0146e3193b33348c7 158 SMART SM00065 31 158 7.5E-4 T 06-07-2017 IPR003018 GAF domain GO:0005515 GTHT12_RS14440 06e0005a3a3759e0146e3193b33348c7 158 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 98 115 - T 06-07-2017 IPR000614 Free Met sulfoxide reductase conserved site GTHT12_RS14440 06e0005a3a3759e0146e3193b33348c7 158 Pfam PF13185 GAF domain 53 154 7.8E-15 T 06-07-2017 IPR003018 GAF domain GO:0005515 GTHT12_RS14440 06e0005a3a3759e0146e3193b33348c7 158 Gene3D G3DSA:3.30.450.40 11 155 3.8E-57 T 06-07-2017 IPR029016 GAF domain-like GTHT12_RS14440 06e0005a3a3759e0146e3193b33348c7 158 SUPERFAMILY SSF55781 10 155 5.89E-48 T 06-07-2017 IPR029016 GAF domain-like GTHT12_RS07485 0c894456c45fb92e8701f0da2a0fa266 419 Pfam PF07690 Major Facilitator Superfamily 16 372 3.7E-38 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS07485 0c894456c45fb92e8701f0da2a0fa266 419 Gene3D G3DSA:1.20.1250.20 8 189 8.6E-30 T 06-07-2017 GTHT12_RS07485 0c894456c45fb92e8701f0da2a0fa266 419 Gene3D G3DSA:1.20.1250.20 208 410 2.5E-19 T 06-07-2017 GTHT12_RS07485 0c894456c45fb92e8701f0da2a0fa266 419 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 79 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 GTHT12_RS07485 0c894456c45fb92e8701f0da2a0fa266 419 SUPERFAMILY SSF103473 5 408 4.19E-54 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS15975 562cc2b3387ba061fce5900488679e82 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 252 49.805 T 06-07-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 GTHT12_RS15975 562cc2b3387ba061fce5900488679e82 252 Pfam PF00977 Histidine biosynthesis protein 5 235 2.8E-90 T 06-07-2017 IPR006062 Histidine biosynthesis GO:0000105 GTHT12_RS15975 562cc2b3387ba061fce5900488679e82 252 SUPERFAMILY SSF51366 3 252 2.35E-84 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 GTHT12_RS15975 562cc2b3387ba061fce5900488679e82 252 Gene3D G3DSA:3.20.20.70 4 252 3.3E-106 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS15975 562cc2b3387ba061fce5900488679e82 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 2 252 1.7E-120 T 06-07-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 GTHT12_RS05445 2034019ea96f7f555f14154701e694e4 324 Gene3D G3DSA:3.40.50.720 148 263 2.1E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS05445 2034019ea96f7f555f14154701e694e4 324 SMART SM00829 10 322 3.2E-56 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 GTHT12_RS05445 2034019ea96f7f555f14154701e694e4 324 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 322 3.1E-89 T 06-07-2017 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 GTHT12_RS05445 2034019ea96f7f555f14154701e694e4 324 Pfam PF00107 Zinc-binding dehydrogenase 151 272 8.4E-36 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 GTHT12_RS05445 2034019ea96f7f555f14154701e694e4 324 SUPERFAMILY SSF51735 112 289 4.37E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS05445 2034019ea96f7f555f14154701e694e4 324 SUPERFAMILY SSF50129 1 138 5.02E-40 T 06-07-2017 IPR011032 GroES-like GTHT12_RS05445 2034019ea96f7f555f14154701e694e4 324 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 140 161 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 GTHT12_RS05445 2034019ea96f7f555f14154701e694e4 324 Gene3D G3DSA:3.90.180.10 1 147 4.6E-47 T 06-07-2017 IPR011032 GroES-like GTHT12_RS05445 2034019ea96f7f555f14154701e694e4 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 87 2.0E-10 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 GTHT12_RS05615 187e1c957a72dd474370a6aec33bf832 319 Gene3D G3DSA:3.20.20.70 4 302 1.3E-73 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS05615 187e1c957a72dd474370a6aec33bf832 319 SUPERFAMILY SSF51412 2 316 2.75E-69 T 06-07-2017 GTHT12_RS05615 187e1c957a72dd474370a6aec33bf832 319 Pfam PF03060 Nitronate monooxygenase 5 76 6.7E-18 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 GTHT12_RS05615 187e1c957a72dd474370a6aec33bf832 319 Pfam PF03060 Nitronate monooxygenase 79 307 1.8E-52 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 GTHT12_RS08500 69e19b652a981311204644124be27420 249 SUPERFAMILY SSF55469 1 248 1.44E-74 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 GTHT12_RS08500 69e19b652a981311204644124be27420 249 Pfam PF00881 Nitroreductase family 8 165 1.3E-22 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 GTHT12_RS08500 69e19b652a981311204644124be27420 249 Gene3D G3DSA:3.40.109.10 1 248 7.5E-77 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 GTHT12_RS08500 69e19b652a981311204644124be27420 249 PIRSF PIRSF005426 1 249 1.6E-91 T 06-07-2017 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 GTHT12_RS03920 d9b564f6900ae0508bfd290dfa9c83c5 339 Gene3D G3DSA:3.40.50.2300 180 317 6.0E-51 T 06-07-2017 GTHT12_RS03920 d9b564f6900ae0508bfd290dfa9c83c5 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.7E-20 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS03920 d9b564f6900ae0508bfd290dfa9c83c5 339 SUPERFAMILY SSF53822 62 337 3.62E-82 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS03920 d9b564f6900ae0508bfd290dfa9c83c5 339 Pfam PF13377 Periplasmic binding protein-like domain 176 336 1.2E-38 T 06-07-2017 GTHT12_RS03920 d9b564f6900ae0508bfd290dfa9c83c5 339 Gene3D G3DSA:3.40.50.2300 55 179 9.9E-45 T 06-07-2017 GTHT12_RS03920 d9b564f6900ae0508bfd290dfa9c83c5 339 SUPERFAMILY SSF47413 2 60 1.13E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS03920 d9b564f6900ae0508bfd290dfa9c83c5 339 Gene3D G3DSA:1.10.260.40 3 54 3.0E-26 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS03920 d9b564f6900ae0508bfd290dfa9c83c5 339 SMART SM00354 2 72 1.2E-31 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS01905 a7b92539e2377b7f4b7c380f9093f3ec 357 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 241 260 - T 06-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 GTHT12_RS01905 a7b92539e2377b7f4b7c380f9093f3ec 357 SMART SM01329 5 348 3.7E-165 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 GTHT12_RS01905 a7b92539e2377b7f4b7c380f9093f3ec 357 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 1 351 9.7E-152 T 06-07-2017 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 GTHT12_RS01905 a7b92539e2377b7f4b7c380f9093f3ec 357 SUPERFAMILY SSF53659 3 351 5.76E-116 T 06-07-2017 GTHT12_RS01905 a7b92539e2377b7f4b7c380f9093f3ec 357 Gene3D G3DSA:3.40.718.10 2 352 5.7E-116 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 GTHT12_RS01905 a7b92539e2377b7f4b7c380f9093f3ec 357 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 348 1.3E-94 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 GTHT12_RS05685 ba5eae50b04fc6b06fc2a609457c125a 331 Hamap MF_01664 Heme A synthase [ctaA]. 15 315 31.173 T 06-07-2017 IPR023755 Heme A synthase, type 1 GO:0006784|GO:0016020|GO:0016627|GO:0055114 GTHT12_RS05685 ba5eae50b04fc6b06fc2a609457c125a 331 Pfam PF02628 Cytochrome oxidase assembly protein 21 300 2.4E-38 T 06-07-2017 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 GTHT12_RS13875 c16aa3a21f27d280cde988e967a92c68 515 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 1 509 43.462 T 06-07-2017 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 GTHT12_RS13875 c16aa3a21f27d280cde988e967a92c68 515 Pfam PF00682 HMGL-like 3 272 2.6E-92 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 GTHT12_RS13875 c16aa3a21f27d280cde988e967a92c68 515 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 3 497 1.1E-234 T 06-07-2017 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 GTHT12_RS13875 c16aa3a21f27d280cde988e967a92c68 515 SMART SM00917 368 500 5.2E-36 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 GTHT12_RS13875 c16aa3a21f27d280cde988e967a92c68 515 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 06-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 GTHT12_RS13875 c16aa3a21f27d280cde988e967a92c68 515 Gene3D G3DSA:3.20.20.70 2 346 4.2E-143 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS13875 c16aa3a21f27d280cde988e967a92c68 515 SUPERFAMILY SSF110921 398 499 1.83E-19 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 GTHT12_RS13875 c16aa3a21f27d280cde988e967a92c68 515 Pfam PF08502 LeuA allosteric (dimerisation) domain 369 499 3.7E-37 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 GTHT12_RS13875 c16aa3a21f27d280cde988e967a92c68 515 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 198 211 - T 06-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 GTHT12_RS13875 c16aa3a21f27d280cde988e967a92c68 515 SUPERFAMILY SSF51569 2 290 6.23E-95 T 06-07-2017 GTHT12_RS05910 912c1a5d56cbb5df056ef268678d49e1 377 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 173 2.6E-46 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 GTHT12_RS05910 912c1a5d56cbb5df056ef268678d49e1 377 SMART SM00865 207 324 8.5E-57 T 06-07-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 GTHT12_RS05910 912c1a5d56cbb5df056ef268678d49e1 377 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 06-07-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 GTHT12_RS05910 912c1a5d56cbb5df056ef268678d49e1 377 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 365 40.026 T 06-07-2017 IPR000158 Cell division protein FtsZ GO:0005525 GTHT12_RS05910 912c1a5d56cbb5df056ef268678d49e1 377 Pfam PF12327 FtsZ family, C-terminal domain 222 315 1.2E-33 T 06-07-2017 IPR024757 Cell division protein FtsZ, C-terminal GTHT12_RS05910 912c1a5d56cbb5df056ef268678d49e1 377 SUPERFAMILY SSF55307 204 319 8.01E-45 T 06-07-2017 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 GTHT12_RS05910 912c1a5d56cbb5df056ef268678d49e1 377 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 8 322 2.7E-142 T 06-07-2017 IPR000158 Cell division protein FtsZ GO:0005525 GTHT12_RS05910 912c1a5d56cbb5df056ef268678d49e1 377 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 06-07-2017 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 GTHT12_RS05910 912c1a5d56cbb5df056ef268678d49e1 377 PRINTS PR00423 Cell division protein FtsZ signature 189 211 4.0E-53 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 GTHT12_RS05910 912c1a5d56cbb5df056ef268678d49e1 377 PRINTS PR00423 Cell division protein FtsZ signature 98 118 4.0E-53 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 GTHT12_RS05910 912c1a5d56cbb5df056ef268678d49e1 377 PRINTS PR00423 Cell division protein FtsZ signature 212 233 4.0E-53 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 GTHT12_RS05910 912c1a5d56cbb5df056ef268678d49e1 377 PRINTS PR00423 Cell division protein FtsZ signature 126 147 4.0E-53 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 GTHT12_RS05910 912c1a5d56cbb5df056ef268678d49e1 377 Gene3D G3DSA:3.40.50.1440 13 214 9.6E-100 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 GTHT12_RS05910 912c1a5d56cbb5df056ef268678d49e1 377 SUPERFAMILY SSF52490 12 208 1.3E-74 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 GTHT12_RS05910 912c1a5d56cbb5df056ef268678d49e1 377 SMART SM00864 13 205 5.5E-121 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 GTHT12_RS05910 912c1a5d56cbb5df056ef268678d49e1 377 Gene3D G3DSA:3.30.1330.20 215 318 2.0E-49 T 06-07-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 GTHT12_RS12015 bc96acb399ebae155059a8f6d984e615 597 Gene3D G3DSA:1.10.287.130 361 421 3.0E-21 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS12015 bc96acb399ebae155059a8f6d984e615 597 SMART SM00304 198 250 2.5E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS12015 bc96acb399ebae155059a8f6d984e615 597 Gene3D G3DSA:3.30.565.10 422 595 1.3E-55 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS12015 bc96acb399ebae155059a8f6d984e615 597 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 482 591 1.6E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS12015 bc96acb399ebae155059a8f6d984e615 597 SUPERFAMILY SSF55874 424 592 3.54E-53 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS12015 bc96acb399ebae155059a8f6d984e615 597 Pfam PF00512 His Kinase A (phospho-acceptor) domain 369 435 1.8E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS12015 bc96acb399ebae155059a8f6d984e615 597 SMART SM00388 368 435 6.2E-22 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS12015 bc96acb399ebae155059a8f6d984e615 597 Pfam PF00672 HAMP domain 179 246 8.9E-17 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS12015 bc96acb399ebae155059a8f6d984e615 597 SUPERFAMILY SSF47384 352 436 2.75E-21 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS12015 bc96acb399ebae155059a8f6d984e615 597 SUPERFAMILY SSF55785 250 360 2.23E-7 T 06-07-2017 IPR000014 PAS domain GTHT12_RS12015 bc96acb399ebae155059a8f6d984e615 597 Gene3D G3DSA:3.30.450.20 250 360 2.9E-10 T 06-07-2017 GTHT12_RS12015 bc96acb399ebae155059a8f6d984e615 597 SUPERFAMILY SSF158472 199 246 7.85E-10 T 06-07-2017 GTHT12_RS12015 bc96acb399ebae155059a8f6d984e615 597 SMART SM00387 481 593 1.7E-43 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS12015 bc96acb399ebae155059a8f6d984e615 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 553 571 1.1E-18 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS12015 bc96acb399ebae155059a8f6d984e615 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 536 546 1.1E-18 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS12015 bc96acb399ebae155059a8f6d984e615 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 532 1.1E-18 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS12015 bc96acb399ebae155059a8f6d984e615 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 577 590 1.1E-18 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS03565 a4f4f5baf7f8f69573da35e5a368da49 449 Gene3D G3DSA:3.30.1490.20 219 252 3.5E-4 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GTHT12_RS03565 a4f4f5baf7f8f69573da35e5a368da49 449 Pfam PF14398 YheC/D like ATP-grasp 182 436 1.3E-83 T 06-07-2017 IPR026838 Endospore coat-associated protein YheC/D GTHT12_RS03565 a4f4f5baf7f8f69573da35e5a368da49 449 SUPERFAMILY SSF56059 205 411 1.86E-11 T 06-07-2017 GTHT12_RS16305 bfcbf460a82ee9ff613a715903b4060b 341 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 100 247 3.7E-43 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain GTHT12_RS16305 bfcbf460a82ee9ff613a715903b4060b 341 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 100 248 4.6E-40 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain GTHT12_RS08830 1311695f9f377ce7c53d825080eb8f47 70 Pfam PF04397 LytTr DNA-binding domain 2 64 1.5E-11 T 06-07-2017 IPR007492 LytTR DNA-binding domain GO:0003677 GTHT12_RS08830 1311695f9f377ce7c53d825080eb8f47 70 Gene3D G3DSA:2.40.50.40 3 29 1.0E-7 T 06-07-2017 GTHT12_RS15670 0da13c51bfec5624f67b8b5b1fc27e9d 795 SUPERFAMILY SSF48179 358 458 4.08E-18 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GTHT12_RS15670 0da13c51bfec5624f67b8b5b1fc27e9d 795 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 205 1.6E-45 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 GTHT12_RS15670 0da13c51bfec5624f67b8b5b1fc27e9d 795 Gene3D G3DSA:3.90.226.10 485 671 1.2E-23 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS15670 0da13c51bfec5624f67b8b5b1fc27e9d 795 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 208 305 2.0E-10 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 GTHT12_RS15670 0da13c51bfec5624f67b8b5b1fc27e9d 795 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 364 417 3.9E-5 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 GTHT12_RS15670 0da13c51bfec5624f67b8b5b1fc27e9d 795 SUPERFAMILY SSF51735 4 206 4.97E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS15670 0da13c51bfec5624f67b8b5b1fc27e9d 795 Pfam PF00378 Enoyl-CoA hydratase/isomerase 490 624 2.4E-11 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 GTHT12_RS15670 0da13c51bfec5624f67b8b5b1fc27e9d 795 SUPERFAMILY SSF48179 206 326 1.96E-22 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GTHT12_RS15670 0da13c51bfec5624f67b8b5b1fc27e9d 795 Gene3D G3DSA:1.10.1040.10 209 306 7.3E-16 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 GTHT12_RS15670 0da13c51bfec5624f67b8b5b1fc27e9d 795 Gene3D G3DSA:1.10.1040.10 359 435 4.5E-12 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 GTHT12_RS15670 0da13c51bfec5624f67b8b5b1fc27e9d 795 Gene3D G3DSA:3.40.50.720 3 208 4.7E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS15670 0da13c51bfec5624f67b8b5b1fc27e9d 795 SUPERFAMILY SSF52096 484 792 1.07E-39 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS14445 fa90ee25d6f0015ad498ac3067cb6f6a 611 Pfam PF00990 Diguanylate cyclase, GGDEF domain 453 598 7.1E-43 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS14445 fa90ee25d6f0015ad498ac3067cb6f6a 611 SUPERFAMILY SSF55781 150 310 2.4E-19 T 06-07-2017 IPR029016 GAF domain-like GTHT12_RS14445 fa90ee25d6f0015ad498ac3067cb6f6a 611 SUPERFAMILY SSF55073 456 604 9.42E-44 T 06-07-2017 IPR029787 Nucleotide cyclase GTHT12_RS14445 fa90ee25d6f0015ad498ac3067cb6f6a 611 Gene3D G3DSA:3.30.450.40 148 289 1.5E-12 T 06-07-2017 IPR029016 GAF domain-like GTHT12_RS14445 fa90ee25d6f0015ad498ac3067cb6f6a 611 Gene3D G3DSA:3.30.450.40 389 448 1.6E-6 T 06-07-2017 IPR029016 GAF domain-like GTHT12_RS14445 fa90ee25d6f0015ad498ac3067cb6f6a 611 Gene3D G3DSA:3.30.70.270 453 604 4.8E-47 T 06-07-2017 GTHT12_RS14445 fa90ee25d6f0015ad498ac3067cb6f6a 611 SMART SM00267 440 603 1.2E-57 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS14445 fa90ee25d6f0015ad498ac3067cb6f6a 611 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 447 603 6.8E-44 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS14445 fa90ee25d6f0015ad498ac3067cb6f6a 611 Gene3D G3DSA:3.30.450.40 290 349 4.7E-4 T 06-07-2017 IPR029016 GAF domain-like GTHT12_RS14445 fa90ee25d6f0015ad498ac3067cb6f6a 611 SMART SM00065 150 293 0.0052 T 06-07-2017 IPR003018 GAF domain GO:0005515 GTHT12_RS14445 fa90ee25d6f0015ad498ac3067cb6f6a 611 SUPERFAMILY SSF55781 280 437 2.16E-11 T 06-07-2017 IPR029016 GAF domain-like GTHT12_RS05410 7bd8af6006f49329ae1aa78afc8fe4ca 300 SUPERFAMILY SSF48179 176 297 1.25E-39 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GTHT12_RS05410 7bd8af6006f49329ae1aa78afc8fe4ca 300 Gene3D G3DSA:1.10.1040.10 176 297 5.7E-45 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 GTHT12_RS05410 7bd8af6006f49329ae1aa78afc8fe4ca 300 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 15 171 3.8E-54 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 GTHT12_RS05410 7bd8af6006f49329ae1aa78afc8fe4ca 300 PIRSF PIRSF000103 8 299 1.9E-75 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 GTHT12_RS05410 7bd8af6006f49329ae1aa78afc8fe4ca 300 Gene3D G3DSA:3.40.50.720 12 175 3.9E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS05410 7bd8af6006f49329ae1aa78afc8fe4ca 300 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 18 31 - T 06-07-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 GTHT12_RS05410 7bd8af6006f49329ae1aa78afc8fe4ca 300 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 177 296 3.1E-37 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 GTHT12_RS05410 7bd8af6006f49329ae1aa78afc8fe4ca 300 SUPERFAMILY SSF51735 14 175 4.85E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS11840 32690c5ca37ab96fd4bf7eca052e7b06 196 Hamap MF_01124 Adapter protein MecA [mecA]. 1 193 23.119 T 06-07-2017 IPR008681 Negative regulator of genetic competence, MecA GTHT12_RS11840 32690c5ca37ab96fd4bf7eca052e7b06 196 PIRSF PIRSF029008 1 195 2.7E-55 T 06-07-2017 IPR008681 Negative regulator of genetic competence, MecA GTHT12_RS11840 32690c5ca37ab96fd4bf7eca052e7b06 196 Pfam PF05389 Negative regulator of genetic competence (MecA) 101 189 7.1E-14 T 06-07-2017 IPR008681 Negative regulator of genetic competence, MecA GTHT12_RS11840 32690c5ca37ab96fd4bf7eca052e7b06 196 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 89 1.5E-21 T 06-07-2017 IPR008681 Negative regulator of genetic competence, MecA GTHT12_RS07340 8d37843471b3e50d0dc3d89c970ad07d 316 Gene3D G3DSA:1.10.3470.10 23 314 4.8E-62 T 06-07-2017 IPR029022 ABC transporter, BtuC-like GTHT12_RS07340 8d37843471b3e50d0dc3d89c970ad07d 316 SUPERFAMILY SSF81345 6 311 2.22E-58 T 06-07-2017 IPR029022 ABC transporter, BtuC-like GTHT12_RS07340 8d37843471b3e50d0dc3d89c970ad07d 316 Pfam PF01032 FecCD transport family 29 311 2.6E-55 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 GTHT12_RS05050 bee5979fd37e9849d15746cc1d24ce94 220 Pfam PF12710 haloacid dehalogenase-like hydrolase 8 178 1.5E-21 T 06-07-2017 GTHT12_RS05050 bee5979fd37e9849d15746cc1d24ce94 220 SUPERFAMILY SSF56784 1 214 9.76E-52 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS05050 bee5979fd37e9849d15746cc1d24ce94 220 Gene3D G3DSA:3.40.50.1000 73 204 3.3E-17 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS05050 bee5979fd37e9849d15746cc1d24ce94 220 Gene3D G3DSA:3.40.50.1000 6 22 3.3E-17 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS05050 bee5979fd37e9849d15746cc1d24ce94 220 TIGRFAM TIGR01489 DKMTPPase-SF: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 4 187 1.0E-48 T 06-07-2017 IPR006384 Pyridoxal phosphate phosphatase-related GO:0016791 GTHT12_RS05050 bee5979fd37e9849d15746cc1d24ce94 220 TIGRFAM TIGR03333 salvage_mtnX: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase 6 217 6.0E-118 T 06-07-2017 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 GTHT12_RS05050 bee5979fd37e9849d15746cc1d24ce94 220 Hamap MF_01680 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase [mtnX]. 3 217 51.802 T 06-07-2017 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 GTHT12_RS05050 bee5979fd37e9849d15746cc1d24ce94 220 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 7 179 1.1E-33 T 06-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 GTHT12_RS12425 2a7290ae6a5ef1364035e7ce23eff0a8 327 SMART SM00861 4 179 1.5E-72 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain GTHT12_RS12425 2a7290ae6a5ef1364035e7ce23eff0a8 327 SUPERFAMILY SSF52518 2 204 3.21E-75 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS12425 2a7290ae6a5ef1364035e7ce23eff0a8 327 Gene3D G3DSA:3.40.50.920 195 324 1.1E-42 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GTHT12_RS12425 2a7290ae6a5ef1364035e7ce23eff0a8 327 SUPERFAMILY SSF52922 188 324 1.14E-39 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GTHT12_RS12425 2a7290ae6a5ef1364035e7ce23eff0a8 327 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 1.8E-53 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain GTHT12_RS12425 2a7290ae6a5ef1364035e7ce23eff0a8 327 Pfam PF02780 Transketolase, C-terminal domain 194 317 2.7E-39 T 06-07-2017 IPR033248 Transketolase, C-terminal domain GTHT12_RS12425 2a7290ae6a5ef1364035e7ce23eff0a8 327 Gene3D G3DSA:3.40.50.970 4 194 2.7E-89 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS18230 8e5229b4e4be619de71a64df279a265b 218 Pfam PF01424 R3H domain 147 204 3.3E-13 T 06-07-2017 IPR001374 R3H domain GO:0003676 GTHT12_RS18230 8e5229b4e4be619de71a64df279a265b 218 Pfam PF14804 Jag N-terminus 7 55 4.6E-20 T 06-07-2017 IPR032782 Jag, N-terminal GTHT12_RS18230 8e5229b4e4be619de71a64df279a265b 218 Gene3D G3DSA:3.30.30.80 2 57 2.4E-18 T 06-07-2017 IPR032782 Jag, N-terminal GTHT12_RS18230 8e5229b4e4be619de71a64df279a265b 218 Gene3D G3DSA:3.30.1370.50 138 213 2.0E-28 T 06-07-2017 IPR001374 R3H domain GO:0003676 GTHT12_RS18230 8e5229b4e4be619de71a64df279a265b 218 Gene3D G3DSA:3.30.300.120 59 137 2.0E-22 T 06-07-2017 GTHT12_RS18230 8e5229b4e4be619de71a64df279a265b 218 SMART SM01245 5 57 7.5E-25 T 06-07-2017 IPR032782 Jag, N-terminal GTHT12_RS18230 8e5229b4e4be619de71a64df279a265b 218 SMART SM00393 127 206 3.6E-16 T 06-07-2017 IPR001374 R3H domain GO:0003676 GTHT12_RS18230 8e5229b4e4be619de71a64df279a265b 218 Pfam PF13083 KH domain 67 129 1.6E-14 T 06-07-2017 GTHT12_RS18230 8e5229b4e4be619de71a64df279a265b 218 SUPERFAMILY SSF82708 149 205 1.41E-8 T 06-07-2017 IPR001374 R3H domain GO:0003676 GTHT12_RS14915 a66012b9e15273c3054da0f683a53a1a 264 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 15 227 3.6E-31 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 GTHT12_RS14915 a66012b9e15273c3054da0f683a53a1a 264 SUPERFAMILY SSF51219 6 244 3.4E-86 T 06-07-2017 IPR016031 Tryptophan RNA-binding attenuator protein-like domain GTHT12_RS14915 a66012b9e15273c3054da0f683a53a1a 264 Pfam PF01987 Mitochondrial biogenesis AIM24 8 225 2.1E-67 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 GTHT12_RS14915 a66012b9e15273c3054da0f683a53a1a 264 Gene3D G3DSA:3.60.160.10 1 246 2.0E-103 T 06-07-2017 IPR002838 Mitochondrial biogenesis protein AIM24 GTHT12_RS09315 37095fd5a49dcec24db17742d90b188c 83 Pfam PF10751 Protein of unknown function (DUF2535) 1 83 3.5E-40 T 06-07-2017 IPR019687 Protein of unknown function DUF2535 GTHT12_RS13925 c0dfd3982c021cf0bd90cbe9036e3a41 264 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 69 77 - T 06-07-2017 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS13925 c0dfd3982c021cf0bd90cbe9036e3a41 264 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 214 4.5E-41 T 06-07-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS13925 c0dfd3982c021cf0bd90cbe9036e3a41 264 SUPERFAMILY SSF53681 108 261 4.36E-40 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS13925 c0dfd3982c021cf0bd90cbe9036e3a41 264 Hamap MF_00258 Glutamate racemase [murI]. 3 255 41.019 T 06-07-2017 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS13925 c0dfd3982c021cf0bd90cbe9036e3a41 264 TIGRFAM TIGR00067 glut_race: glutamate racemase 5 253 7.5E-90 T 06-07-2017 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS13925 c0dfd3982c021cf0bd90cbe9036e3a41 264 Gene3D G3DSA:3.40.50.1860 3 172 2.6E-59 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS13925 c0dfd3982c021cf0bd90cbe9036e3a41 264 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 179 189 - T 06-07-2017 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS13925 c0dfd3982c021cf0bd90cbe9036e3a41 264 SUPERFAMILY SSF53681 4 106 1.01E-36 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS12440 996a0791c8f093d718e567a1c80291f9 370 Hamap MF_00542 Probable butyrate kinase [buk]. 1 370 178.734 T 06-07-2017 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 GTHT12_RS12440 996a0791c8f093d718e567a1c80291f9 370 Gene3D G3DSA:3.30.420.40 5 183 2.5E-90 T 06-07-2017 GTHT12_RS12440 996a0791c8f093d718e567a1c80291f9 370 Gene3D G3DSA:3.30.420.40 184 341 1.0E-48 T 06-07-2017 GTHT12_RS12440 996a0791c8f093d718e567a1c80291f9 370 Pfam PF00871 Acetokinase family 8 340 9.8E-77 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 GTHT12_RS12440 996a0791c8f093d718e567a1c80291f9 370 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 182 199 - T 06-07-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 GTHT12_RS12440 996a0791c8f093d718e567a1c80291f9 370 PIRSF PIRSF036458 4 359 1.1E-177 T 06-07-2017 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 GTHT12_RS12440 996a0791c8f093d718e567a1c80291f9 370 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 7 356 1.7E-177 T 06-07-2017 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 GTHT12_RS12440 996a0791c8f093d718e567a1c80291f9 370 SUPERFAMILY SSF53067 119 349 1.83E-59 T 06-07-2017 GTHT12_RS12440 996a0791c8f093d718e567a1c80291f9 370 PRINTS PR00471 Acetate kinase family signature 8 19 1.4E-17 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 GTHT12_RS12440 996a0791c8f093d718e567a1c80291f9 370 PRINTS PR00471 Acetate kinase family signature 300 316 1.4E-17 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 GTHT12_RS12440 996a0791c8f093d718e567a1c80291f9 370 PRINTS PR00471 Acetate kinase family signature 277 290 1.4E-17 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 GTHT12_RS12440 996a0791c8f093d718e567a1c80291f9 370 PRINTS PR00471 Acetate kinase family signature 182 203 1.4E-17 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 GTHT12_RS12440 996a0791c8f093d718e567a1c80291f9 370 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 8 19 - T 06-07-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 GTHT12_RS12440 996a0791c8f093d718e567a1c80291f9 370 SUPERFAMILY SSF53067 6 175 3.74E-75 T 06-07-2017 GTHT12_RS02360 f35716d9277cca8be6ecf608e582bd71 240 SUPERFAMILY SSF100950 46 237 3.68E-42 T 06-07-2017 GTHT12_RS02360 f35716d9277cca8be6ecf608e582bd71 240 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 55 237 5.6E-31 T 06-07-2017 IPR003741 LUD domain GTHT12_RS02360 f35716d9277cca8be6ecf608e582bd71 240 Gene3D G3DSA:3.40.50.10420 47 237 1.5E-48 T 06-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain GTHT12_RS02360 f35716d9277cca8be6ecf608e582bd71 240 Hamap MF_02104 Lactate utilization protein C [lutC]. 5 237 50.035 T 06-07-2017 IPR022823 Lactate utilization protein C GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 Gene3D G3DSA:1.25.40.10 1149 1366 2.5E-22 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 SMART SM00028 1036 1069 17.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 SMART SM00028 1302 1335 36.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 SMART SM00028 906 939 3.0E-5 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 SMART SM00028 731 764 1.8E-5 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 SMART SM00028 1164 1197 150.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 SMART SM00028 940 973 490.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 SMART SM00028 663 696 77.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 SMART SM00028 561 594 4.5E-4 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 SMART SM00028 874 905 200.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 SMART SM00028 1002 1035 2.4 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 SMART SM00028 697 730 130.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 SMART SM00028 187 220 180.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 SUPERFAMILY SSF48452 1208 1365 5.31E-17 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 SMART SM00671 874 905 0.1 T 06-07-2017 IPR006597 Sel1-like repeat GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 SMART SM00671 731 762 66.0 T 06-07-2017 IPR006597 Sel1-like repeat GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 Pfam PF13432 Tetratricopeptide repeat 863 903 0.0068 T 06-07-2017 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 SUPERFAMILY SSF48452 862 1075 7.59E-20 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 SUPERFAMILY SSF48452 112 256 1.02E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 SUPERFAMILY SSF48452 511 787 1.12E-28 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 Pfam PF07719 Tetratricopeptide repeat 731 764 8.9E-6 T 06-07-2017 IPR013105 Tetratricopeptide repeat 2 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 Pfam PF13529 Peptidase_C39 like family 313 416 1.9E-11 T 06-07-2017 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 Pfam PF13181 Tetratricopeptide repeat 700 726 0.1 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 Pfam PF13181 Tetratricopeptide repeat 908 938 1.7E-5 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 Gene3D G3DSA:1.25.40.10 475 554 2.4E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 Gene3D G3DSA:1.25.40.10 114 275 2.4E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 Gene3D G3DSA:1.25.40.10 862 1074 1.8E-30 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 Gene3D G3DSA:1.25.40.10 563 818 1.2E-43 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 Pfam PF14559 Tetratricopeptide repeat 1025 1075 1.0E-6 T 06-07-2017 GTHT12_RS09545 54a1475da4b0a92ff07934691e734bdf 1386 Pfam PF12895 Anaphase-promoting complex, cyclosome, subunit 3 516 585 6.6E-7 T 06-07-2017 GTHT12_RS07420 f1c2c8efc546655bccfbfd24d15581e1 493 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 153 475 8.0E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS07420 f1c2c8efc546655bccfbfd24d15581e1 493 Gene3D G3DSA:1.10.1060.10 5 155 6.4E-39 T 06-07-2017 GTHT12_RS07420 f1c2c8efc546655bccfbfd24d15581e1 493 Gene3D G3DSA:3.50.50.60 243 421 1.2E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS07420 f1c2c8efc546655bccfbfd24d15581e1 493 SUPERFAMILY SSF51971 151 421 1.65E-66 T 06-07-2017 GTHT12_RS07420 f1c2c8efc546655bccfbfd24d15581e1 493 SUPERFAMILY SSF46548 2 163 1.73E-36 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 GTHT12_RS07420 f1c2c8efc546655bccfbfd24d15581e1 493 Gene3D G3DSA:3.40.50.720 423 491 1.6E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS07420 f1c2c8efc546655bccfbfd24d15581e1 493 Gene3D G3DSA:3.40.50.720 156 242 1.6E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS07420 f1c2c8efc546655bccfbfd24d15581e1 493 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 139 4.2E-21 T 06-07-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 GTHT12_RS07420 f1c2c8efc546655bccfbfd24d15581e1 493 PRINTS PR00419 Adrenodoxin reductase family signature 154 176 4.7E-27 T 06-07-2017 GTHT12_RS07420 f1c2c8efc546655bccfbfd24d15581e1 493 PRINTS PR00419 Adrenodoxin reductase family signature 295 309 4.7E-27 T 06-07-2017 GTHT12_RS07420 f1c2c8efc546655bccfbfd24d15581e1 493 PRINTS PR00419 Adrenodoxin reductase family signature 219 229 4.7E-27 T 06-07-2017 GTHT12_RS07420 f1c2c8efc546655bccfbfd24d15581e1 493 PRINTS PR00419 Adrenodoxin reductase family signature 177 190 4.7E-27 T 06-07-2017 GTHT12_RS07420 f1c2c8efc546655bccfbfd24d15581e1 493 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 493 5.5E-248 T 06-07-2017 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 GTHT12_RS07395 5459f6ad5a106d7ef77157d5f50c9fcb 569 Pfam PF05547 Immune inhibitor A peptidase M6 445 553 4.1E-10 T 06-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 GTHT12_RS07395 5459f6ad5a106d7ef77157d5f50c9fcb 569 SUPERFAMILY SSF56601 76 431 6.8E-99 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS07395 5459f6ad5a106d7ef77157d5f50c9fcb 569 Gene3D G3DSA:3.40.710.10 69 429 6.6E-105 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS07395 5459f6ad5a106d7ef77157d5f50c9fcb 569 Pfam PF00144 Beta-lactamase 85 428 3.9E-83 T 06-07-2017 IPR001466 Beta-lactamase-related GTHT12_RS03985 8ba6f6f0ae05e024815c951a97e17b3f 357 PIRSF PIRSF019574 1 356 7.6E-134 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 GTHT12_RS03985 8ba6f6f0ae05e024815c951a97e17b3f 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 56 77 5.2E-60 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 GTHT12_RS03985 8ba6f6f0ae05e024815c951a97e17b3f 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 130 146 5.2E-60 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 GTHT12_RS03985 8ba6f6f0ae05e024815c951a97e17b3f 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 156 170 5.2E-60 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 GTHT12_RS03985 8ba6f6f0ae05e024815c951a97e17b3f 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 40 56 5.2E-60 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 GTHT12_RS03985 8ba6f6f0ae05e024815c951a97e17b3f 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 83 97 5.2E-60 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 GTHT12_RS03985 8ba6f6f0ae05e024815c951a97e17b3f 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 99 112 5.2E-60 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 GTHT12_RS03985 8ba6f6f0ae05e024815c951a97e17b3f 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 174 193 5.2E-60 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 GTHT12_RS03985 8ba6f6f0ae05e024815c951a97e17b3f 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 255 274 5.2E-60 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 GTHT12_RS03985 8ba6f6f0ae05e024815c951a97e17b3f 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 300 326 5.2E-60 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 GTHT12_RS03985 8ba6f6f0ae05e024815c951a97e17b3f 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 211 230 5.2E-60 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 GTHT12_RS03985 8ba6f6f0ae05e024815c951a97e17b3f 357 Gene3D G3DSA:3.40.190.10 152 305 2.0E-58 T 06-07-2017 GTHT12_RS03985 8ba6f6f0ae05e024815c951a97e17b3f 357 Pfam PF13416 Bacterial extracellular solute-binding protein 50 320 5.2E-42 T 06-07-2017 GTHT12_RS03985 8ba6f6f0ae05e024815c951a97e17b3f 357 SUPERFAMILY SSF53850 34 353 6.34E-98 T 06-07-2017 GTHT12_RS03985 8ba6f6f0ae05e024815c951a97e17b3f 357 Gene3D G3DSA:3.40.190.10 35 151 6.4E-28 T 06-07-2017 GTHT12_RS16015 e09925e23958f89b73fc7dada398788f 214 Hamap MF_01250 Pyrophosphatase PpaX [ppaX]. 1 214 45.46 T 06-07-2017 IPR023733 Pyrophosphatase PpaX GO:0008152|GO:0016462 KEGG: 00190+3.6.1.1 GTHT12_RS16015 e09925e23958f89b73fc7dada398788f 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 181 2.4E-50 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS16015 e09925e23958f89b73fc7dada398788f 214 Gene3D G3DSA:3.40.50.1000 1 19 1.7E-39 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS16015 e09925e23958f89b73fc7dada398788f 214 Gene3D G3DSA:3.40.50.1000 77 210 1.7E-39 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS16015 e09925e23958f89b73fc7dada398788f 214 Gene3D G3DSA:1.10.150.240 20 76 5.8E-10 T 06-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 GTHT12_RS16015 e09925e23958f89b73fc7dada398788f 214 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 83 175 2.3E-9 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 GTHT12_RS16015 e09925e23958f89b73fc7dada398788f 214 SUPERFAMILY SSF56784 1 210 6.8E-59 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS05785 f20c9108e5b143e54be67e560f1450fa 411 TIGRFAM TIGR02871 spore_ylbJ: sporulation integral membrane protein YlbJ 12 394 2.6E-148 T 06-07-2017 IPR014226 Sporulation integral membrane protein YlbJ GTHT12_RS05785 f20c9108e5b143e54be67e560f1450fa 411 Pfam PF07670 Nucleoside recognition 47 142 1.6E-7 T 06-07-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 GTHT12_RS08395 ea2bbc8a24dbd82a1bfa995afcc5c045 334 SUPERFAMILY SSF51679 3 332 1.88E-76 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 GTHT12_RS08395 ea2bbc8a24dbd82a1bfa995afcc5c045 334 Pfam PF00296 Luciferase-like monooxygenase 17 303 4.0E-37 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 GTHT12_RS08395 ea2bbc8a24dbd82a1bfa995afcc5c045 334 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 5 331 5.5E-126 T 06-07-2017 IPR019949 Luciferase family oxidoreductase, group 1 GTHT12_RS08395 ea2bbc8a24dbd82a1bfa995afcc5c045 334 Gene3D G3DSA:3.20.20.30 4 332 3.7E-88 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 GTHT12_RS10005 b88e1cb8541ecd74b6482b3a604c469d 513 Gene3D G3DSA:3.40.50.300 255 502 1.6E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10005 b88e1cb8541ecd74b6482b3a604c469d 513 SUPERFAMILY SSF52540 247 488 2.78E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10005 b88e1cb8541ecd74b6482b3a604c469d 513 Gene3D G3DSA:3.40.50.300 5 228 1.9E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10005 b88e1cb8541ecd74b6482b3a604c469d 513 SUPERFAMILY SSF52540 5 227 6.86E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10005 b88e1cb8541ecd74b6482b3a604c469d 513 ProSitePatterns PS00211 ABC transporters family signature. 409 423 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS10005 b88e1cb8541ecd74b6482b3a604c469d 513 SMART SM00382 289 492 4.0E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS10005 b88e1cb8541ecd74b6482b3a604c469d 513 SMART SM00382 30 220 1.0E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS10005 b88e1cb8541ecd74b6482b3a604c469d 513 Pfam PF00005 ABC transporter 281 436 6.1E-18 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS10005 b88e1cb8541ecd74b6482b3a604c469d 513 Pfam PF00005 ABC transporter 21 172 3.0E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS13845 969cd7950e992958992693aa543fe7aa 421 SUPERFAMILY SSF57716 11 46 1.71E-11 T 06-07-2017 GTHT12_RS13845 969cd7950e992958992693aa543fe7aa 421 Gene3D G3DSA:3.40.50.300 288 305 4.8E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13845 969cd7950e992958992693aa543fe7aa 421 Gene3D G3DSA:3.40.50.300 62 250 4.8E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13845 969cd7950e992958992693aa543fe7aa 421 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 311 389 6.5E-18 T 06-07-2017 IPR019489 Clp ATPase, C-terminal GTHT12_RS13845 969cd7950e992958992693aa543fe7aa 421 Pfam PF06689 ClpX C4-type zinc finger 11 48 1.9E-20 T 06-07-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 GTHT12_RS13845 969cd7950e992958992693aa543fe7aa 421 SMART SM01086 311 406 9.5E-34 T 06-07-2017 IPR019489 Clp ATPase, C-terminal GTHT12_RS13845 969cd7950e992958992693aa543fe7aa 421 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 2 406 4.3E-213 T 06-07-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 GTHT12_RS13845 969cd7950e992958992693aa543fe7aa 421 SMART SM00382 108 269 4.0E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS13845 969cd7950e992958992693aa543fe7aa 421 Pfam PF07724 AAA domain (Cdc48 subfamily) 109 305 4.8E-52 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 GTHT12_RS13845 969cd7950e992958992693aa543fe7aa 421 Gene3D G3DSA:1.10.8.60 310 409 2.4E-37 T 06-07-2017 GTHT12_RS13845 969cd7950e992958992693aa543fe7aa 421 SUPERFAMILY SSF52540 59 396 5.48E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13845 969cd7950e992958992693aa543fe7aa 421 SMART SM00994 10 49 8.0E-24 T 06-07-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 GTHT12_RS13845 969cd7950e992958992693aa543fe7aa 421 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 409 53.824 T 06-07-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 GTHT12_RS14785 46e3ceeade0bf00a5584360e00f764ab 528 Pfam PF01293 Phosphoenolpyruvate carboxykinase 19 480 9.6E-232 T 06-07-2017 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 GTHT12_RS14785 46e3ceeade0bf00a5584360e00f764ab 528 SUPERFAMILY SSF53795 213 520 4.58E-138 T 06-07-2017 GTHT12_RS14785 46e3ceeade0bf00a5584360e00f764ab 528 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 15 527 2.4E-249 T 06-07-2017 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 GTHT12_RS14785 46e3ceeade0bf00a5584360e00f764ab 528 PIRSF PIRSF006294 2 527 3.8E-249 T 06-07-2017 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 GTHT12_RS14785 46e3ceeade0bf00a5584360e00f764ab 528 Hamap MF_00453 Phosphoenolpyruvate carboxykinase [ATP] [pckA]. 12 528 56.971 T 06-07-2017 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 GTHT12_RS14785 46e3ceeade0bf00a5584360e00f764ab 528 Gene3D G3DSA:3.40.449.10 19 212 5.9E-86 T 06-07-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 GTHT12_RS14785 46e3ceeade0bf00a5584360e00f764ab 528 Gene3D G3DSA:3.90.228.20 213 275 4.7E-122 T 06-07-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 GTHT12_RS14785 46e3ceeade0bf00a5584360e00f764ab 528 Gene3D G3DSA:3.90.228.20 336 519 4.7E-122 T 06-07-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 GTHT12_RS14785 46e3ceeade0bf00a5584360e00f764ab 528 SUPERFAMILY SSF68923 15 212 9.59E-84 T 06-07-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 GTHT12_RS06330 822311aaf2a38b1c197c0e47df218586 527 Pfam PF08345 Flagellar M-ring protein C-terminal 257 401 3.9E-25 T 06-07-2017 IPR013556 Flagellar M-ring C-terminal GTHT12_RS06330 822311aaf2a38b1c197c0e47df218586 527 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 10 526 6.6E-117 T 06-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 GTHT12_RS06330 822311aaf2a38b1c197c0e47df218586 527 PIRSF PIRSF004862 1 527 2.0E-110 T 06-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 GTHT12_RS06330 822311aaf2a38b1c197c0e47df218586 527 Pfam PF01514 Secretory protein of YscJ/FliF family 31 220 1.1E-60 T 06-07-2017 IPR006182 Secretory protein YscJ/FliF GTHT12_RS06330 822311aaf2a38b1c197c0e47df218586 527 PRINTS PR01009 Flagellar M-ring protein signature 154 168 4.6E-22 T 06-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 GTHT12_RS06330 822311aaf2a38b1c197c0e47df218586 527 PRINTS PR01009 Flagellar M-ring protein signature 270 288 4.6E-22 T 06-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 GTHT12_RS06330 822311aaf2a38b1c197c0e47df218586 527 PRINTS PR01009 Flagellar M-ring protein signature 122 140 4.6E-22 T 06-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 GTHT12_RS06330 822311aaf2a38b1c197c0e47df218586 527 PRINTS PR01009 Flagellar M-ring protein signature 198 216 4.6E-22 T 06-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 GTHT12_RS06330 822311aaf2a38b1c197c0e47df218586 527 PRINTS PR01009 Flagellar M-ring protein signature 348 372 4.6E-22 T 06-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 GTHT12_RS11535 0cc41fd92bbb4141e9e0381552054186 329 TIGRFAM TIGR00122 birA_repr_reg: biotin operon repressor 14 81 7.7E-21 T 06-07-2017 IPR004409 Biotin operon repressor, helix-turn-helix domain GO:0006355 KEGG: 00780+6.3.4.15 GTHT12_RS11535 0cc41fd92bbb4141e9e0381552054186 329 Gene3D G3DSA:2.30.30.100 284 329 2.1E-7 T 06-07-2017 GTHT12_RS11535 0cc41fd92bbb4141e9e0381552054186 329 Gene3D G3DSA:1.10.10.10 8 67 8.6E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS11535 0cc41fd92bbb4141e9e0381552054186 329 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 90 328 3.2E-70 T 06-07-2017 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GTHT12_RS11535 0cc41fd92bbb4141e9e0381552054186 329 Pfam PF08279 HTH domain 10 64 2.4E-15 T 06-07-2017 IPR013196 Helix-turn-helix, type 11 GTHT12_RS11535 0cc41fd92bbb4141e9e0381552054186 329 Gene3D G3DSA:3.30.930.10 78 279 1.8E-67 T 06-07-2017 GTHT12_RS11535 0cc41fd92bbb4141e9e0381552054186 329 Pfam PF03099 Biotin/lipoate A/B protein ligase family 94 218 1.5E-16 T 06-07-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 GTHT12_RS11535 0cc41fd92bbb4141e9e0381552054186 329 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 12 329 37.192 T 06-07-2017 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 GTHT12_RS11535 0cc41fd92bbb4141e9e0381552054186 329 SUPERFAMILY SSF46785 7 65 1.7E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS11535 0cc41fd92bbb4141e9e0381552054186 329 SUPERFAMILY SSF55681 76 280 1.46E-63 T 06-07-2017 GTHT12_RS11535 0cc41fd92bbb4141e9e0381552054186 329 Pfam PF02237 Biotin protein ligase C terminal domain 284 329 3.5E-12 T 06-07-2017 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GTHT12_RS00725 08c4df82e4dd680339f12d033c241ad7 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 1.3E-24 T 06-07-2017 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00725 08c4df82e4dd680339f12d033c241ad7 61 SUPERFAMILY SSF57716 3 61 3.99E-22 T 06-07-2017 GTHT12_RS00725 08c4df82e4dd680339f12d033c241ad7 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 26.28 T 06-07-2017 IPR023053 Ribosomal protein S14, type Z GTHT12_RS00725 08c4df82e4dd680339f12d033c241ad7 61 Gene3D G3DSA:4.10.830.10 2 61 1.9E-28 T 06-07-2017 GTHT12_RS00725 08c4df82e4dd680339f12d033c241ad7 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 06-07-2017 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS09590 54105f9a856e7b3fccd7ec477d37ee53 336 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 11 194 2.1E-32 T 06-07-2017 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 GTHT12_RS09590 54105f9a856e7b3fccd7ec477d37ee53 336 Gene3D G3DSA:3.30.70.20 242 308 1.6E-13 T 06-07-2017 GTHT12_RS09590 54105f9a856e7b3fccd7ec477d37ee53 336 SUPERFAMILY SSF53323 10 195 2.88E-33 T 06-07-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 GTHT12_RS09590 54105f9a856e7b3fccd7ec477d37ee53 336 SUPERFAMILY SSF54862 243 312 1.47E-15 T 06-07-2017 GTHT12_RS09590 54105f9a856e7b3fccd7ec477d37ee53 336 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 19 191 4.0E-27 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 GTHT12_RS09590 54105f9a856e7b3fccd7ec477d37ee53 336 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 252 263 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GTHT12_RS09590 54105f9a856e7b3fccd7ec477d37ee53 336 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 291 302 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GTHT12_RS09590 54105f9a856e7b3fccd7ec477d37ee53 336 Gene3D G3DSA:3.40.920.10 10 194 2.6E-41 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 GTHT12_RS09590 54105f9a856e7b3fccd7ec477d37ee53 336 Pfam PF12838 4Fe-4S dicluster domain 251 305 1.6E-8 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain GTHT12_RS12720 0be2ccefb2b091faa30bbbeb557ff8fd 327 Pfam PF00248 Aldo/keto reductase family 15 315 7.3E-65 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain GTHT12_RS12720 0be2ccefb2b091faa30bbbeb557ff8fd 327 PRINTS PR00069 Aldo-keto reductase signature 105 123 1.5E-7 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GTHT12_RS12720 0be2ccefb2b091faa30bbbeb557ff8fd 327 PRINTS PR00069 Aldo-keto reductase signature 137 154 1.5E-7 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GTHT12_RS12720 0be2ccefb2b091faa30bbbeb557ff8fd 327 PRINTS PR00069 Aldo-keto reductase signature 42 66 1.5E-7 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GTHT12_RS12720 0be2ccefb2b091faa30bbbeb557ff8fd 327 SUPERFAMILY SSF51430 1 318 1.7E-83 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain GTHT12_RS12720 0be2ccefb2b091faa30bbbeb557ff8fd 327 Gene3D G3DSA:3.20.20.100 1 320 4.3E-85 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain GTHT12_RS18840 c61225d64b80f07f4f3397f0fccc8930 411 Pfam PF00872 Transposase, Mutator family 16 376 7.8E-141 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS02075 7fc6a246d8685cbf5da2220c2433164b 410 PRINTS PR00173 Glutamate-aspartate symporter signature 347 367 6.3E-15 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS02075 7fc6a246d8685cbf5da2220c2433164b 410 PRINTS PR00173 Glutamate-aspartate symporter signature 285 311 6.3E-15 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS02075 7fc6a246d8685cbf5da2220c2433164b 410 PRINTS PR00173 Glutamate-aspartate symporter signature 7 27 6.3E-15 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS02075 7fc6a246d8685cbf5da2220c2433164b 410 PRINTS PR00173 Glutamate-aspartate symporter signature 183 202 6.3E-15 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS02075 7fc6a246d8685cbf5da2220c2433164b 410 PRINTS PR00173 Glutamate-aspartate symporter signature 320 339 6.3E-15 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS02075 7fc6a246d8685cbf5da2220c2433164b 410 Pfam PF00375 Sodium:dicarboxylate symporter family 13 393 1.8E-70 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS02075 7fc6a246d8685cbf5da2220c2433164b 410 SUPERFAMILY SSF118215 13 394 7.85E-96 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS02075 7fc6a246d8685cbf5da2220c2433164b 410 Gene3D G3DSA:1.10.3860.10 6 401 2.9E-89 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS02075 7fc6a246d8685cbf5da2220c2433164b 410 Hamap MF_01582 Serine/threonine transporter SstT [sstT]. 1 402 35.354 T 06-07-2017 IPR023025 Serine/threonine transporter SstT GO:0015293|GO:0015826|GO:0032329 GTHT12_RS03460 e9edd9c089c03656573932988a85fd21 308 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 304 8.5E-74 T 06-07-2017 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 GTHT12_RS03460 e9edd9c089c03656573932988a85fd21 308 SUPERFAMILY SSF48179 178 301 3.23E-30 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GTHT12_RS03460 e9edd9c089c03656573932988a85fd21 308 SUPERFAMILY SSF51735 1 183 6.35E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS03460 e9edd9c089c03656573932988a85fd21 308 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 178 299 2.3E-26 T 06-07-2017 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 GTHT12_RS03460 e9edd9c089c03656573932988a85fd21 308 Gene3D G3DSA:1.10.1040.10 178 301 2.7E-33 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 GTHT12_RS03460 e9edd9c089c03656573932988a85fd21 308 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 151 1.1E-35 T 06-07-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 GTHT12_RS03460 e9edd9c089c03656573932988a85fd21 308 Gene3D G3DSA:3.40.50.720 1 175 1.4E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS04070 4096f1e27ead0f203ae6c10239cb9801 77 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 11 76 7.1E-28 T 06-07-2017 IPR018720 Domain of unknown function DUF2249 GTHT12_RS02470 a99561572a7f5e9ee0c52b619f56d163 235 Gene3D G3DSA:3.40.50.620 16 206 8.2E-60 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS02470 a99561572a7f5e9ee0c52b619f56d163 235 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 1 234 42.064 T 06-07-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 GTHT12_RS02470 a99561572a7f5e9ee0c52b619f56d163 235 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 38 210 5.1E-51 T 06-07-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 GTHT12_RS02470 a99561572a7f5e9ee0c52b619f56d163 235 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 44 232 4.5E-76 T 06-07-2017 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 GTHT12_RS02470 a99561572a7f5e9ee0c52b619f56d163 235 PIRSF PIRSF000857 6 235 2.4E-88 T 06-07-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 GTHT12_RS02470 a99561572a7f5e9ee0c52b619f56d163 235 SUPERFAMILY SSF52402 17 198 1.21E-52 T 06-07-2017 GTHT12_RS02470 a99561572a7f5e9ee0c52b619f56d163 235 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 25 233 6.1E-93 T 06-07-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 GTHT12_RS15395 80415acda4b94bde9100415a701f2f78 270 Gene3D G3DSA:3.40.50.1980 124 255 1.8E-32 T 06-07-2017 GTHT12_RS15395 80415acda4b94bde9100415a701f2f78 270 Gene3D G3DSA:3.40.50.1980 2 119 7.3E-29 T 06-07-2017 GTHT12_RS15395 80415acda4b94bde9100415a701f2f78 270 SUPERFAMILY SSF53807 2 255 1.14E-55 T 06-07-2017 GTHT12_RS15395 80415acda4b94bde9100415a701f2f78 270 Pfam PF01497 Periplasmic binding protein 3 231 6.5E-29 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 GTHT12_RS16630 8faf18642a0a9f1580f40347644a8683 435 PIRSF PIRSF038800 12 427 2.0E-157 T 06-07-2017 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 GTHT12_RS16630 8faf18642a0a9f1580f40347644a8683 435 Gene3D G3DSA:3.90.1150.10 274 431 4.3E-52 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS16630 8faf18642a0a9f1580f40347644a8683 435 Gene3D G3DSA:3.40.640.10 92 265 2.1E-17 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS16630 8faf18642a0a9f1580f40347644a8683 435 Hamap MF_01970 Kynureninase [kynU]. 8 419 41.136 T 06-07-2017 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 GTHT12_RS16630 8faf18642a0a9f1580f40347644a8683 435 Pfam PF00266 Aminotransferase class-V 89 383 1.1E-19 T 06-07-2017 IPR000192 Aminotransferase class V domain GTHT12_RS16630 8faf18642a0a9f1580f40347644a8683 435 SUPERFAMILY SSF53383 16 421 1.32E-82 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS16630 8faf18642a0a9f1580f40347644a8683 435 TIGRFAM TIGR01814 kynureninase: kynureninase 21 420 9.4E-125 T 06-07-2017 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 GTHT12_RS13335 539249e9e9944f7604a0bb3e4416b186 211 Gene3D G3DSA:3.40.50.300 4 206 1.6E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13335 539249e9e9944f7604a0bb3e4416b186 211 PRINTS PR00988 Uridine kinase signature 5 22 4.2E-37 T 06-07-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 GTHT12_RS13335 539249e9e9944f7604a0bb3e4416b186 211 PRINTS PR00988 Uridine kinase signature 80 95 4.2E-37 T 06-07-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 GTHT12_RS13335 539249e9e9944f7604a0bb3e4416b186 211 PRINTS PR00988 Uridine kinase signature 150 161 4.2E-37 T 06-07-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 GTHT12_RS13335 539249e9e9944f7604a0bb3e4416b186 211 PRINTS PR00988 Uridine kinase signature 136 146 4.2E-37 T 06-07-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 GTHT12_RS13335 539249e9e9944f7604a0bb3e4416b186 211 PRINTS PR00988 Uridine kinase signature 172 185 4.2E-37 T 06-07-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 GTHT12_RS13335 539249e9e9944f7604a0bb3e4416b186 211 PRINTS PR00988 Uridine kinase signature 35 46 4.2E-37 T 06-07-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 GTHT12_RS13335 539249e9e9944f7604a0bb3e4416b186 211 Hamap MF_00551 Uridine kinase [udk]. 2 206 42.322 T 06-07-2017 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 GTHT12_RS13335 539249e9e9944f7604a0bb3e4416b186 211 TIGRFAM TIGR00235 udk: uridine kinase 3 206 2.7E-90 T 06-07-2017 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 GTHT12_RS13335 539249e9e9944f7604a0bb3e4416b186 211 SUPERFAMILY SSF52540 3 197 1.51E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13335 539249e9e9944f7604a0bb3e4416b186 211 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 192 1.0E-42 T 06-07-2017 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 GTHT12_RS07915 7c5a3f4593479371e8971998bd738d65 78 Pfam PF11122 Inner spore coat protein D 10 70 1.2E-19 T 06-07-2017 IPR020108 Spore coat protein CotD GTHT12_RS07915 7c5a3f4593479371e8971998bd738d65 78 ProDom PD057197 SPORE COAT CAPSID D INNER D COTD SPORULATION 2 64 2.0E-10 T 06-07-2017 IPR020108 Spore coat protein CotD GTHT12_RS16465 07542416e84fd62edef6777ebb064aa5 119 PIRSF PIRSF009151 1 118 6.5E-59 T 06-07-2017 IPR008497 Protein of unknown function DUF779 GTHT12_RS16465 07542416e84fd62edef6777ebb064aa5 119 Pfam PF05610 Protein of unknown function (DUF779) 16 109 9.9E-50 T 06-07-2017 IPR008497 Protein of unknown function DUF779 GTHT12_RS08520 1f49c89f4889781d6635cdb2f48768b6 247 Hamap MF_01968 NAD-dependent protein deacetylase [cobB]. 6 241 61.054 T 06-07-2017 IPR028628 Sirtuin, class U GO:0034979|GO:0051287 GTHT12_RS08520 1f49c89f4889781d6635cdb2f48768b6 247 Pfam PF02146 Sir2 family 22 194 1.8E-49 T 06-07-2017 IPR003000 Sirtuin family GO:0070403 GTHT12_RS08520 1f49c89f4889781d6635cdb2f48768b6 247 SUPERFAMILY SSF52467 2 244 5.61E-76 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS08520 1f49c89f4889781d6635cdb2f48768b6 247 Gene3D G3DSA:3.30.1600.10 33 72 2.3E-23 T 06-07-2017 IPR026591 Sirtuin family, catalytic core small domain GTHT12_RS08520 1f49c89f4889781d6635cdb2f48768b6 247 Gene3D G3DSA:3.30.1600.10 123 164 2.3E-23 T 06-07-2017 IPR026591 Sirtuin family, catalytic core small domain GTHT12_RS08520 1f49c89f4889781d6635cdb2f48768b6 247 Gene3D G3DSA:3.40.50.1220 85 122 7.0E-43 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS08520 1f49c89f4889781d6635cdb2f48768b6 247 Gene3D G3DSA:3.40.50.1220 170 246 7.0E-43 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS08520 1f49c89f4889781d6635cdb2f48768b6 247 Gene3D G3DSA:3.40.50.1220 4 32 7.0E-43 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS13885 3441d200bba5c4c581dbb13fac58bb66 172 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 77 1.0E-36 T 06-07-2017 GTHT12_RS13885 3441d200bba5c4c581dbb13fac58bb66 172 Gene3D G3DSA:3.30.70.260 1 79 3.4E-32 T 06-07-2017 GTHT12_RS13885 3441d200bba5c4c581dbb13fac58bb66 172 Gene3D G3DSA:3.30.70.1150 85 161 6.7E-32 T 06-07-2017 GTHT12_RS13885 3441d200bba5c4c581dbb13fac58bb66 172 SUPERFAMILY SSF55021 80 160 4.07E-27 T 06-07-2017 GTHT12_RS13885 3441d200bba5c4c581dbb13fac58bb66 172 Pfam PF10369 Small subunit of acetolactate synthase 85 158 2.3E-30 T 06-07-2017 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 GTHT12_RS13885 3441d200bba5c4c581dbb13fac58bb66 172 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 158 7.8E-67 T 06-07-2017 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 GTHT12_RS13885 3441d200bba5c4c581dbb13fac58bb66 172 SUPERFAMILY SSF55021 2 77 1.6E-21 T 06-07-2017 GTHT12_RS13885 3441d200bba5c4c581dbb13fac58bb66 172 Pfam PF01842 ACT domain 4 68 5.7E-15 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 GTHT12_RS04345 4c9dbc15432a010cec61860ebe271b3a 226 PIRSF PIRSF029008 1 225 8.7E-81 T 06-07-2017 IPR008681 Negative regulator of genetic competence, MecA GTHT12_RS04345 4c9dbc15432a010cec61860ebe271b3a 226 Hamap MF_01124 Adapter protein MecA [mecA]. 1 223 27.338 T 06-07-2017 IPR008681 Negative regulator of genetic competence, MecA GTHT12_RS04345 4c9dbc15432a010cec61860ebe271b3a 226 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 219 7.1E-55 T 06-07-2017 IPR008681 Negative regulator of genetic competence, MecA GTHT12_RS11175 b57f1f4a51c0548cea70fa197e52420c 309 Hamap MF_00313 Glutaminase [glsA]. 5 309 47.597 T 06-07-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 GTHT12_RS11175 b57f1f4a51c0548cea70fa197e52420c 309 Pfam PF04960 Glutaminase 23 309 7.7E-115 T 06-07-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 GTHT12_RS11175 b57f1f4a51c0548cea70fa197e52420c 309 Gene3D G3DSA:3.40.710.10 7 309 4.3E-121 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS11175 b57f1f4a51c0548cea70fa197e52420c 309 TIGRFAM TIGR03814 Gln_ase: glutaminase A 10 309 1.3E-125 T 06-07-2017 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 GTHT12_RS11175 b57f1f4a51c0548cea70fa197e52420c 309 SUPERFAMILY SSF56601 6 309 1.21E-115 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS15460 a9fad4de531794e4374d6bc37e9b93f3 353 PIRSF PIRSF038945 1 348 2.8E-157 T 06-07-2017 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 GTHT12_RS15460 a9fad4de531794e4374d6bc37e9b93f3 353 Gene3D G3DSA:3.40.50.1100 59 143 1.5E-42 T 06-07-2017 GTHT12_RS15460 a9fad4de531794e4374d6bc37e9b93f3 353 TIGRFAM TIGR00260 thrC: threonine synthase 10 322 1.1E-103 T 06-07-2017 IPR004450 Threonine synthase-like GTHT12_RS15460 a9fad4de531794e4374d6bc37e9b93f3 353 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 24 316 1.9E-80 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GTHT12_RS15460 a9fad4de531794e4374d6bc37e9b93f3 353 SUPERFAMILY SSF53686 7 349 3.8E-107 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GTHT12_RS15460 a9fad4de531794e4374d6bc37e9b93f3 353 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 51 64 - T 06-07-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 GTHT12_RS15460 a9fad4de531794e4374d6bc37e9b93f3 353 Gene3D G3DSA:3.40.50.1100 144 326 8.5E-52 T 06-07-2017 GTHT12_RS11490 dc9fbbeb9dce2f9650f0eada8e943463 430 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 1 429 2.3E-164 T 06-07-2017 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 GTHT12_RS11490 dc9fbbeb9dce2f9650f0eada8e943463 430 Pfam PF00152 tRNA synthetases class II (D, K and N) 111 424 2.7E-83 T 06-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS11490 dc9fbbeb9dce2f9650f0eada8e943463 430 Pfam PF01336 OB-fold nucleic acid binding domain 16 95 2.0E-16 T 06-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 GTHT12_RS11490 dc9fbbeb9dce2f9650f0eada8e943463 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 180 192 3.9E-16 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS11490 dc9fbbeb9dce2f9650f0eada8e943463 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 385 399 3.9E-16 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS11490 dc9fbbeb9dce2f9650f0eada8e943463 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 196 209 3.9E-16 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS11490 dc9fbbeb9dce2f9650f0eada8e943463 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 345 361 3.9E-16 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS11490 dc9fbbeb9dce2f9650f0eada8e943463 430 SUPERFAMILY SSF50249 9 102 7.24E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS11490 dc9fbbeb9dce2f9650f0eada8e943463 430 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 1 430 42.964 T 06-07-2017 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 GTHT12_RS11490 dc9fbbeb9dce2f9650f0eada8e943463 430 SUPERFAMILY SSF55681 110 424 4.58E-101 T 06-07-2017 GTHT12_RS11490 dc9fbbeb9dce2f9650f0eada8e943463 430 Gene3D G3DSA:2.40.50.140 4 101 2.8E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS11490 dc9fbbeb9dce2f9650f0eada8e943463 430 Gene3D G3DSA:3.30.930.10 102 428 5.4E-117 T 06-07-2017 GTHT12_RS08875 9f23148196fdf7e23a16f2d62eb35b3d 202 Pfam PF13649 Methyltransferase domain 47 143 2.0E-14 T 06-07-2017 GTHT12_RS08875 9f23148196fdf7e23a16f2d62eb35b3d 202 SUPERFAMILY SSF53335 22 184 3.1E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS08875 9f23148196fdf7e23a16f2d62eb35b3d 202 Gene3D G3DSA:3.40.50.150 24 183 4.1E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 SUPERFAMILY SSF50447 263 402 2.78E-36 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 Gene3D G3DSA:3.30.70.240 598 683 8.1E-37 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 Hamap MF_00054_B Elongation factor G [fusA]. 6 689 113.262 T 06-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 PRINTS PR00315 GTP-binding elongation factor signature 94 105 4.2E-17 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 PRINTS PR00315 GTP-binding elongation factor signature 78 88 4.2E-17 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 PRINTS PR00315 GTP-binding elongation factor signature 130 139 4.2E-17 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.2E-17 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.2E-17 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 SUPERFAMILY SSF54211 477 597 1.11E-45 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 SUPERFAMILY SSF52540 6 280 6.04E-115 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 SMART SM00838 598 685 1.4E-60 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 180 1.7E-42 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 Pfam PF03144 Elongation factor Tu domain 2 322 389 5.6E-15 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 SMART SM00889 478 596 1.3E-75 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 Pfam PF00009 Elongation factor Tu GTP binding domain 9 280 2.5E-71 T 06-07-2017 GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 Pfam PF14492 Elongation Factor G, domain II 402 475 2.0E-37 T 06-07-2017 IPR009022 Elongation factor G, III-V domain GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 SUPERFAMILY SSF54980 598 688 2.06E-32 T 06-07-2017 IPR009022 Elongation factor G, III-V domain GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 Gene3D G3DSA:2.40.30.10 304 403 4.5E-39 T 06-07-2017 GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 Pfam PF03764 Elongation factor G, domain IV 477 595 2.4E-49 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 Gene3D G3DSA:3.30.230.10 482 597 2.7E-52 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 690 0.0 T 06-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 Gene3D G3DSA:3.30.70.870 404 478 1.5E-40 T 06-07-2017 GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 Pfam PF00679 Elongation factor G C-terminus 598 684 5.3E-33 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 Gene3D G3DSA:3.40.50.300 7 285 7.5E-110 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00645 7d1501e3ff46834da563ee73a07bdf18 692 SUPERFAMILY SSF54980 400 478 1.55E-26 T 06-07-2017 IPR009022 Elongation factor G, III-V domain GTHT12_RS15930 3ba21306f6be418eb81e21fd8c246562 85 PRINTS PR00107 Phosphocarrier protein signature 53 70 1.6E-20 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like GTHT12_RS15930 3ba21306f6be418eb81e21fd8c246562 85 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.6E-20 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like GTHT12_RS15930 3ba21306f6be418eb81e21fd8c246562 85 PRINTS PR00107 Phosphocarrier protein signature 38 53 1.6E-20 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like GTHT12_RS15930 3ba21306f6be418eb81e21fd8c246562 85 SUPERFAMILY SSF55594 3 83 1.7E-28 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like GTHT12_RS15930 3ba21306f6be418eb81e21fd8c246562 85 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 06-07-2017 IPR002114 Phosphotransferase system, HPr serine phosphorylation site GTHT12_RS15930 3ba21306f6be418eb81e21fd8c246562 85 Pfam PF00381 PTS HPr component phosphorylation site 2 82 2.9E-30 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like GTHT12_RS15930 3ba21306f6be418eb81e21fd8c246562 85 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 1.9E-30 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like GTHT12_RS15930 3ba21306f6be418eb81e21fd8c246562 85 Gene3D G3DSA:3.30.1340.10 1 83 1.5E-33 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like GTHT12_RS06275 574190a321da6e31de32514ffa721270 386 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 44.653 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GTHT12_RS06275 574190a321da6e31de32514ffa721270 386 Gene3D G3DSA:3.30.470.20 96 239 4.3E-61 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 GTHT12_RS06275 574190a321da6e31de32514ffa721270 386 Pfam PF08442 ATP-grasp domain 2 203 7.2E-84 T 06-07-2017 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GTHT12_RS06275 574190a321da6e31de32514ffa721270 386 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 06-07-2017 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 GTHT12_RS06275 574190a321da6e31de32514ffa721270 386 Gene3D G3DSA:3.30.1490.20 22 95 4.5E-35 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GTHT12_RS06275 574190a321da6e31de32514ffa721270 386 SUPERFAMILY SSF56059 1 238 1.53E-87 T 06-07-2017 GTHT12_RS06275 574190a321da6e31de32514ffa721270 386 SUPERFAMILY SSF52210 239 385 6.15E-56 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 GTHT12_RS06275 574190a321da6e31de32514ffa721270 386 Pfam PF00549 CoA-ligase 262 380 5.1E-26 T 06-07-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 GTHT12_RS06275 574190a321da6e31de32514ffa721270 386 PIRSF PIRSF001554 1 386 9.4E-159 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GTHT12_RS06275 574190a321da6e31de32514ffa721270 386 Gene3D G3DSA:3.40.50.261 241 385 5.0E-69 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 GTHT12_RS06275 574190a321da6e31de32514ffa721270 386 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 1.3E-171 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 GTHT12_RS01195 bc7917e84e71675f325c45b650134fd2 154 SUPERFAMILY SSF109854 1 148 1.96E-37 T 06-07-2017 GTHT12_RS01195 bc7917e84e71675f325c45b650134fd2 154 Pfam PF05163 DinB family 6 148 3.2E-29 T 06-07-2017 IPR007837 DNA damage-inducible protein DinB GTHT12_RS01195 bc7917e84e71675f325c45b650134fd2 154 Gene3D G3DSA:1.20.120.450 4 144 4.8E-37 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase GTHT12_RS04830 b295c94d5e5b084a5ecc1acf1ffebe1e 336 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS04830 b295c94d5e5b084a5ecc1acf1ffebe1e 336 Pfam PF00005 ABC transporter 32 174 6.3E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS04830 b295c94d5e5b084a5ecc1acf1ffebe1e 336 SMART SM00382 40 231 4.9E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS04830 b295c94d5e5b084a5ecc1acf1ffebe1e 336 SUPERFAMILY SSF52540 15 237 5.22E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS04830 b295c94d5e5b084a5ecc1acf1ffebe1e 336 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 23 319 3.0E-114 T 06-07-2017 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 GTHT12_RS04830 b295c94d5e5b084a5ecc1acf1ffebe1e 336 Pfam PF13732 Domain of unknown function (DUF4162) 228 317 4.9E-9 T 06-07-2017 IPR025302 Domain of unknown function DUF4162 GTHT12_RS04830 b295c94d5e5b084a5ecc1acf1ffebe1e 336 Gene3D G3DSA:3.40.50.300 8 250 5.9E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS14275 b45c26227b6be6da06748a136fe39bfd 1093 Gene3D G3DSA:2.40.50.140 938 1012 2.6E-5 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS14275 b45c26227b6be6da06748a136fe39bfd 1093 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 278 701 1.0E-164 T 06-07-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS14275 b45c26227b6be6da06748a136fe39bfd 1093 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 3 979 0.0 T 06-07-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS14275 b45c26227b6be6da06748a136fe39bfd 1093 SUPERFAMILY SSF89550 4 250 8.24E-15 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 GTHT12_RS14275 b45c26227b6be6da06748a136fe39bfd 1093 Pfam PF14579 Helix-hairpin-helix motif 774 860 1.7E-22 T 06-07-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS14275 b45c26227b6be6da06748a136fe39bfd 1093 SMART SM00481 4 71 2.5E-20 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 GTHT12_RS14275 b45c26227b6be6da06748a136fe39bfd 1093 Gene3D G3DSA:3.20.20.140 1 244 1.4E-22 T 06-07-2017 GTHT12_RS14275 b45c26227b6be6da06748a136fe39bfd 1093 Pfam PF02811 PHP domain 5 164 3.4E-30 T 06-07-2017 IPR004013 PHP domain GO:0003824 GTHT12_RS02290 c2c31d505c79ba22d8ad975f1bec0012 385 SUPERFAMILY SSF103473 4 380 1.44E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS02290 c2c31d505c79ba22d8ad975f1bec0012 385 Pfam PF07690 Major Facilitator Superfamily 15 230 1.1E-29 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS02290 c2c31d505c79ba22d8ad975f1bec0012 385 PRINTS PR01035 Tetracycline resistance protein signature 160 180 3.3E-17 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS02290 c2c31d505c79ba22d8ad975f1bec0012 385 PRINTS PR01035 Tetracycline resistance protein signature 19 35 3.3E-17 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS02290 c2c31d505c79ba22d8ad975f1bec0012 385 PRINTS PR01035 Tetracycline resistance protein signature 132 154 3.3E-17 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS02290 c2c31d505c79ba22d8ad975f1bec0012 385 PRINTS PR01035 Tetracycline resistance protein signature 266 287 3.3E-17 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS02290 c2c31d505c79ba22d8ad975f1bec0012 385 Gene3D G3DSA:1.20.1250.20 205 380 8.4E-19 T 06-07-2017 GTHT12_RS02290 c2c31d505c79ba22d8ad975f1bec0012 385 Gene3D G3DSA:1.20.1250.20 8 189 7.6E-32 T 06-07-2017 GTHT12_RS11980 f95101313c377857ba19df43cd27570b 319 SUPERFAMILY SSF53807 44 315 1.65E-70 T 06-07-2017 GTHT12_RS11980 f95101313c377857ba19df43cd27570b 319 Gene3D G3DSA:3.40.50.1980 190 316 4.9E-37 T 06-07-2017 GTHT12_RS11980 f95101313c377857ba19df43cd27570b 319 Pfam PF01497 Periplasmic binding protein 67 292 1.2E-41 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 GTHT12_RS11980 f95101313c377857ba19df43cd27570b 319 Gene3D G3DSA:3.40.50.1980 63 184 1.5E-33 T 06-07-2017 GTHT12_RS15880 6597267be6ae133b105cf4a6a15e4ded 430 Pfam PF03952 Enolase, N-terminal domain 4 134 2.0E-63 T 06-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS15880 6597267be6ae133b105cf4a6a15e4ded 430 PIRSF PIRSF001400 1 427 4.1E-200 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS15880 6597267be6ae133b105cf4a6a15e4ded 430 Hamap MF_00318 Enolase [eno]. 2 413 46.878 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS15880 6597267be6ae133b105cf4a6a15e4ded 430 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 427 9.6E-224 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS15880 6597267be6ae133b105cf4a6a15e4ded 430 ProSitePatterns PS00164 Enolase signature. 336 349 - T 06-07-2017 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15880 6597267be6ae133b105cf4a6a15e4ded 430 SUPERFAMILY SSF51604 138 427 2.12E-134 T 06-07-2017 IPR029065 Enolase C-terminal domain-like GTHT12_RS15880 6597267be6ae133b105cf4a6a15e4ded 430 SMART SM01193 4 134 3.5E-101 T 06-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS15880 6597267be6ae133b105cf4a6a15e4ded 430 SMART SM01192 139 427 6.4E-235 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS15880 6597267be6ae133b105cf4a6a15e4ded 430 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 425 3.4E-144 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS15880 6597267be6ae133b105cf4a6a15e4ded 430 PRINTS PR00148 Enolase signature 365 382 3.1E-48 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS15880 6597267be6ae133b105cf4a6a15e4ded 430 PRINTS PR00148 Enolase signature 313 324 3.1E-48 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS15880 6597267be6ae133b105cf4a6a15e4ded 430 PRINTS PR00148 Enolase signature 336 350 3.1E-48 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS15880 6597267be6ae133b105cf4a6a15e4ded 430 PRINTS PR00148 Enolase signature 161 174 3.1E-48 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS15880 6597267be6ae133b105cf4a6a15e4ded 430 PRINTS PR00148 Enolase signature 37 51 3.1E-48 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS15880 6597267be6ae133b105cf4a6a15e4ded 430 PRINTS PR00148 Enolase signature 107 123 3.1E-48 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS15880 6597267be6ae133b105cf4a6a15e4ded 430 Gene3D G3DSA:3.30.390.10 4 126 9.0E-60 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS15880 6597267be6ae133b105cf4a6a15e4ded 430 Gene3D G3DSA:3.20.20.120 128 426 9.2E-143 T 06-07-2017 IPR029065 Enolase C-terminal domain-like GTHT12_RS15880 6597267be6ae133b105cf4a6a15e4ded 430 SUPERFAMILY SSF54826 3 138 1.31E-60 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS17240 cf8864cb6d092163fa9cd603105f5502 184 SUPERFAMILY SSF51161 38 173 1.8E-28 T 06-07-2017 IPR011004 Trimeric LpxA-like GTHT12_RS17240 cf8864cb6d092163fa9cd603105f5502 184 Gene3D G3DSA:2.160.10.10 81 173 6.4E-20 T 06-07-2017 GTHT12_RS17240 cf8864cb6d092163fa9cd603105f5502 184 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 131 163 5.8E-8 T 06-07-2017 IPR001451 Hexapeptide repeat GTHT12_RS18170 992859e503d730bfd2db04f10553aeb3 366 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 366 3.8E-157 T 06-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 GTHT12_RS18170 992859e503d730bfd2db04f10553aeb3 366 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 366 46.757 T 06-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 GTHT12_RS18170 992859e503d730bfd2db04f10553aeb3 366 Pfam PF06071 Protein of unknown function (DUF933) 282 365 4.0E-41 T 06-07-2017 IPR013029 Domain of unknown function DUF933 GTHT12_RS18170 992859e503d730bfd2db04f10553aeb3 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 7.7E-36 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS18170 992859e503d730bfd2db04f10553aeb3 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 7.7E-36 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS18170 992859e503d730bfd2db04f10553aeb3 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 7.7E-36 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS18170 992859e503d730bfd2db04f10553aeb3 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 7.7E-36 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS18170 992859e503d730bfd2db04f10553aeb3 366 SUPERFAMILY SSF81271 282 363 3.27E-36 T 06-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 GTHT12_RS18170 992859e503d730bfd2db04f10553aeb3 366 Gene3D G3DSA:1.10.150.300 131 200 9.3E-30 T 06-07-2017 IPR023192 TGS-like domain GTHT12_RS18170 992859e503d730bfd2db04f10553aeb3 366 PIRSF PIRSF006641 1 366 1.6E-166 T 06-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 GTHT12_RS18170 992859e503d730bfd2db04f10553aeb3 366 Gene3D G3DSA:3.10.20.30 270 366 5.3E-50 T 06-07-2017 IPR012675 Beta-grasp domain GTHT12_RS18170 992859e503d730bfd2db04f10553aeb3 366 Pfam PF01926 50S ribosome-binding GTPase 5 116 5.3E-23 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS18170 992859e503d730bfd2db04f10553aeb3 366 Gene3D G3DSA:3.40.50.300 4 130 3.4E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18170 992859e503d730bfd2db04f10553aeb3 366 Gene3D G3DSA:3.40.50.300 201 269 3.4E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18170 992859e503d730bfd2db04f10553aeb3 366 SUPERFAMILY SSF52540 3 304 1.64E-89 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11675 df2129eaac6bd92ec1f0522f38e5f7dc 256 Gene3D G3DSA:1.10.155.10 2 65 1.4E-8 T 06-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal GTHT12_RS11675 df2129eaac6bd92ec1f0522f38e5f7dc 256 Pfam PF01739 CheR methyltransferase, SAM binding domain 67 239 2.0E-58 T 06-07-2017 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal GTHT12_RS11675 df2129eaac6bd92ec1f0522f38e5f7dc 256 SMART SM00138 1 254 6.7E-102 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 GTHT12_RS11675 df2129eaac6bd92ec1f0522f38e5f7dc 256 Pfam PF03705 CheR methyltransferase, all-alpha domain 2 54 1.1E-15 T 06-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal GTHT12_RS11675 df2129eaac6bd92ec1f0522f38e5f7dc 256 SUPERFAMILY SSF53335 67 243 2.24E-54 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS11675 df2129eaac6bd92ec1f0522f38e5f7dc 256 PRINTS PR00996 Glutamate methyltransferase family signature 97 117 1.9E-39 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 GTHT12_RS11675 df2129eaac6bd92ec1f0522f38e5f7dc 256 PRINTS PR00996 Glutamate methyltransferase family signature 129 145 1.9E-39 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 GTHT12_RS11675 df2129eaac6bd92ec1f0522f38e5f7dc 256 PRINTS PR00996 Glutamate methyltransferase family signature 214 237 1.9E-39 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 GTHT12_RS11675 df2129eaac6bd92ec1f0522f38e5f7dc 256 PRINTS PR00996 Glutamate methyltransferase family signature 60 72 1.9E-39 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 GTHT12_RS11675 df2129eaac6bd92ec1f0522f38e5f7dc 256 PRINTS PR00996 Glutamate methyltransferase family signature 23 36 1.9E-39 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 GTHT12_RS11675 df2129eaac6bd92ec1f0522f38e5f7dc 256 PRINTS PR00996 Glutamate methyltransferase family signature 195 209 1.9E-39 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 GTHT12_RS11675 df2129eaac6bd92ec1f0522f38e5f7dc 256 SUPERFAMILY SSF47757 2 66 1.96E-11 T 06-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal GTHT12_RS11675 df2129eaac6bd92ec1f0522f38e5f7dc 256 Gene3D G3DSA:3.40.50.150 66 252 5.3E-67 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS05795 7a46a63ba6b0d160982f7e824160b959 339 SMART SM00228 119 186 1.2E-7 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS05795 7a46a63ba6b0d160982f7e824160b959 339 SUPERFAMILY SSF54211 173 333 1.21E-22 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS05795 7a46a63ba6b0d160982f7e824160b959 339 Gene3D G3DSA:3.30.230.10 227 333 7.0E-25 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GTHT12_RS05795 7a46a63ba6b0d160982f7e824160b959 339 Gene3D G3DSA:2.30.42.10 128 203 7.7E-20 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS05795 7a46a63ba6b0d160982f7e824160b959 339 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 232 331 3.2E-10 T 06-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 GTHT12_RS05795 7a46a63ba6b0d160982f7e824160b959 339 Pfam PF13180 PDZ domain 124 194 9.5E-17 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS05795 7a46a63ba6b0d160982f7e824160b959 339 SUPERFAMILY SSF50156 120 193 5.26E-14 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS10430 c5561f22b52ec791fb0dba61e158174d 334 SUPERFAMILY SSF52283 5 124 1.32E-30 T 06-07-2017 GTHT12_RS10430 c5561f22b52ec791fb0dba61e158174d 334 SUPERFAMILY SSF51735 104 287 7.89E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS10430 c5561f22b52ec791fb0dba61e158174d 334 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 286 5.4E-60 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 GTHT12_RS10430 c5561f22b52ec791fb0dba61e158174d 334 Gene3D G3DSA:3.40.50.720 4 110 1.0E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS10430 c5561f22b52ec791fb0dba61e158174d 334 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 21 318 2.3E-28 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 GTHT12_RS10430 c5561f22b52ec791fb0dba61e158174d 334 Gene3D G3DSA:3.40.50.720 111 288 1.2E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS14310 5f31d2fff8ec6fe3830e13765fa0268b 226 SUPERFAMILY SSF56281 1 209 2.88E-38 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS14310 5f31d2fff8ec6fe3830e13765fa0268b 226 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 1 226 38.766 T 06-07-2017 IPR022877 Protein of unknown funcion UPF0173 GTHT12_RS14310 5f31d2fff8ec6fe3830e13765fa0268b 226 Gene3D G3DSA:3.60.15.10 1 226 7.1E-67 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS14310 5f31d2fff8ec6fe3830e13765fa0268b 226 SMART SM00849 7 192 2.5E-10 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS14310 5f31d2fff8ec6fe3830e13765fa0268b 226 Pfam PF13483 Beta-lactamase superfamily domain 2 192 2.9E-27 T 06-07-2017 GTHT12_RS08610 4c2b0cbd1552033fb830f53822b5a505 211 Gene3D G3DSA:3.40.30.10 38 201 4.9E-38 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS08610 4c2b0cbd1552033fb830f53822b5a505 211 SUPERFAMILY SSF52833 42 201 9.87E-33 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS08610 4c2b0cbd1552033fb830f53822b5a505 211 Pfam PF02630 SCO1/SenC 41 186 1.9E-15 T 06-07-2017 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS09995 5e09f7c163563cab104899e51eb7f94b 364 Gene3D G3DSA:1.10.10.10 3 79 3.9E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS09995 5e09f7c163563cab104899e51eb7f94b 364 SMART SM00345 12 71 1.9E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS09995 5e09f7c163563cab104899e51eb7f94b 364 Gene3D G3DSA:3.40.50.2300 195 362 1.5E-50 T 06-07-2017 GTHT12_RS09995 5e09f7c163563cab104899e51eb7f94b 364 SUPERFAMILY SSF46785 6 75 1.09E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS09995 5e09f7c163563cab104899e51eb7f94b 364 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 1.0E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS09995 5e09f7c163563cab104899e51eb7f94b 364 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 1.0E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS09995 5e09f7c163563cab104899e51eb7f94b 364 Gene3D G3DSA:3.40.50.2300 82 194 1.1E-32 T 06-07-2017 GTHT12_RS09995 5e09f7c163563cab104899e51eb7f94b 364 Pfam PF13377 Periplasmic binding protein-like domain 196 361 5.8E-37 T 06-07-2017 GTHT12_RS09995 5e09f7c163563cab104899e51eb7f94b 364 SUPERFAMILY SSF53822 83 362 3.26E-66 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS09995 5e09f7c163563cab104899e51eb7f94b 364 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 1.8E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS14585 7360b9c42c24daf32d96a8d577b732d4 214 Pfam PF00571 CBS domain 3 56 7.8E-16 T 06-07-2017 IPR000644 CBS domain GTHT12_RS14585 7360b9c42c24daf32d96a8d577b732d4 214 Pfam PF00571 CBS domain 74 127 5.8E-10 T 06-07-2017 IPR000644 CBS domain GTHT12_RS14585 7360b9c42c24daf32d96a8d577b732d4 214 Pfam PF01842 ACT domain 139 187 2.4E-7 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 GTHT12_RS14585 7360b9c42c24daf32d96a8d577b732d4 214 SUPERFAMILY SSF54631 1 130 1.64E-35 T 06-07-2017 GTHT12_RS14585 7360b9c42c24daf32d96a8d577b732d4 214 Gene3D G3DSA:3.30.70.260 139 199 2.9E-7 T 06-07-2017 GTHT12_RS14585 7360b9c42c24daf32d96a8d577b732d4 214 SUPERFAMILY SSF55021 138 207 3.14E-10 T 06-07-2017 GTHT12_RS14585 7360b9c42c24daf32d96a8d577b732d4 214 SMART SM00116 10 58 4.6E-12 T 06-07-2017 IPR000644 CBS domain GTHT12_RS14585 7360b9c42c24daf32d96a8d577b732d4 214 SMART SM00116 81 128 3.1E-14 T 06-07-2017 IPR000644 CBS domain GTHT12_RS14585 7360b9c42c24daf32d96a8d577b732d4 214 Gene3D G3DSA:3.20.20.70 3 130 5.1E-36 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS00030 374b361b2ed9114dd155e697684e390b 822 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 5 811 25.38 T 06-07-2017 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 GTHT12_RS00030 374b361b2ed9114dd155e697684e390b 822 Gene3D G3DSA:3.30.1360.40 237 333 1.9E-41 T 06-07-2017 IPR024946 Arginine repressor C-terminal-like domain GTHT12_RS00030 374b361b2ed9114dd155e697684e390b 822 Gene3D G3DSA:3.90.199.10 334 398 2.4E-125 T 06-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS00030 374b361b2ed9114dd155e697684e390b 822 Gene3D G3DSA:3.90.199.10 31 236 2.4E-125 T 06-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS00030 374b361b2ed9114dd155e697684e390b 822 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 9 807 0.0 T 06-07-2017 GTHT12_RS00030 374b361b2ed9114dd155e697684e390b 822 SUPERFAMILY SSF56719 31 488 3.14E-186 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 GTHT12_RS00030 374b361b2ed9114dd155e697684e390b 822 SUPERFAMILY SSF101904 500 818 5.75E-114 T 06-07-2017 GTHT12_RS00030 374b361b2ed9114dd155e697684e390b 822 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 33 472 3.7E-166 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS00030 374b361b2ed9114dd155e697684e390b 822 Gene3D G3DSA:2.120.10.90 497 799 7.8E-130 T 06-07-2017 GTHT12_RS00030 374b361b2ed9114dd155e697684e390b 822 SMART SM00434 12 465 3.3E-302 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS00030 374b361b2ed9114dd155e697684e390b 822 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 710 755 1.2E-13 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 GTHT12_RS00030 374b361b2ed9114dd155e697684e390b 822 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 506 552 1.5E-14 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 GTHT12_RS00030 374b361b2ed9114dd155e697684e390b 822 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 555 604 1.3E-8 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 GTHT12_RS00030 374b361b2ed9114dd155e697684e390b 822 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 760 799 3.2E-9 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 GTHT12_RS00030 374b361b2ed9114dd155e697684e390b 822 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 660 705 4.9E-16 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 GTHT12_RS00030 374b361b2ed9114dd155e697684e390b 822 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 612 655 5.3E-7 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 GTHT12_RS07090 1a0d4d52153fd6893046be948f9c3235 211 Pfam PF16167 Domain of unknown function (DUF4871) 85 208 7.1E-22 T 06-07-2017 IPR032366 Protein of unknown function DUF4871 GTHT12_RS06650 bc342be9417dc724d88d1df8e4e8ac9c 243 SUPERFAMILY SSF46785 5 86 3.54E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS06650 bc342be9417dc724d88d1df8e4e8ac9c 243 Pfam PF07702 UTRA domain 96 232 3.0E-27 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 GTHT12_RS06650 bc342be9417dc724d88d1df8e4e8ac9c 243 Gene3D G3DSA:1.10.10.10 5 69 2.4E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS06650 bc342be9417dc724d88d1df8e4e8ac9c 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 73 2.6E-22 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS06650 bc342be9417dc724d88d1df8e4e8ac9c 243 SMART SM00345 14 73 1.2E-22 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS06650 bc342be9417dc724d88d1df8e4e8ac9c 243 Gene3D G3DSA:3.40.1410.10 70 239 7.1E-42 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain GTHT12_RS06650 bc342be9417dc724d88d1df8e4e8ac9c 243 SUPERFAMILY SSF64288 62 239 3.77E-40 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain GTHT12_RS06650 bc342be9417dc724d88d1df8e4e8ac9c 243 SMART SM00866 95 233 9.6E-25 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 GTHT12_RS06650 bc342be9417dc724d88d1df8e4e8ac9c 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 3.4E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS06650 bc342be9417dc724d88d1df8e4e8ac9c 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 3.4E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS04430 b8f8c3dfa081149151891389facf9727 349 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 37 341 1.3E-87 T 06-07-2017 IPR014255 Spore coat protein CotS GTHT12_RS04430 b8f8c3dfa081149151891389facf9727 349 Pfam PF01636 Phosphotransferase enzyme family 39 286 3.6E-20 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase GTHT12_RS04430 b8f8c3dfa081149151891389facf9727 349 SUPERFAMILY SSF56112 22 347 9.53E-49 T 06-07-2017 IPR011009 Protein kinase-like domain GTHT12_RS04430 b8f8c3dfa081149151891389facf9727 349 Gene3D G3DSA:3.90.1200.10 115 343 1.1E-56 T 06-07-2017 GTHT12_RS04430 b8f8c3dfa081149151891389facf9727 349 Gene3D G3DSA:3.30.200.20 10 113 1.4E-32 T 06-07-2017 GTHT12_RS12910 fe0e4c5772b12496ca05eb537665777f 430 SUPERFAMILY SSF103473 14 401 2.62E-36 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS12910 fe0e4c5772b12496ca05eb537665777f 430 Pfam PF07690 Major Facilitator Superfamily 21 336 2.1E-18 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS12910 fe0e4c5772b12496ca05eb537665777f 430 ProSitePatterns PS00217 Sugar transport proteins signature 2. 114 139 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 GTHT12_RS12910 fe0e4c5772b12496ca05eb537665777f 430 Gene3D G3DSA:1.20.1250.20 212 411 1.1E-10 T 06-07-2017 GTHT12_RS12910 fe0e4c5772b12496ca05eb537665777f 430 Gene3D G3DSA:1.20.1250.20 12 199 4.9E-18 T 06-07-2017 GTHT12_RS00515 e1b27246180751c8852bfccc72189f07 363 SUPERFAMILY SSF55931 4 269 1.85E-87 T 06-07-2017 GTHT12_RS00515 e1b27246180751c8852bfccc72189f07 363 ProSitePatterns PS00112 Phosphagen kinase active site signature. 168 174 - T 06-07-2017 IPR022415 ATP:guanido phosphotransferase active site GO:0016301|GO:0016772 Reactome: R-HSA-71288 GTHT12_RS00515 e1b27246180751c8852bfccc72189f07 363 Gene3D G3DSA:3.30.590.10 8 256 2.2E-82 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 GTHT12_RS00515 e1b27246180751c8852bfccc72189f07 363 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 20 254 7.3E-91 T 06-07-2017 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 GTHT12_RS00515 e1b27246180751c8852bfccc72189f07 363 Hamap MF_00602 Protein-arginine kinase [mcsB]. 13 351 39.914 T 06-07-2017 IPR023660 Arginine kinase GO:0016775 GTHT12_RS12945 b347c56eb2930b9b92c30fca3a237356 141 Gene3D G3DSA:1.10.10.10 5 80 1.0E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12945 b347c56eb2930b9b92c30fca3a237356 141 Pfam PF01475 Ferric uptake regulator family 12 129 3.3E-31 T 06-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 GTHT12_RS12945 b347c56eb2930b9b92c30fca3a237356 141 SUPERFAMILY SSF46785 5 133 3.74E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS00120 2e79d0e21675d2da48f02983c0e7b5c0 198 TIGRFAM TIGR00615 recR: recombination protein RecR 2 196 2.7E-90 T 06-07-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 GTHT12_RS00120 2e79d0e21675d2da48f02983c0e7b5c0 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 06-07-2017 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 GTHT12_RS00120 2e79d0e21675d2da48f02983c0e7b5c0 198 Gene3D G3DSA:3.40.50.140 54 72 6.9E-7 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS00120 2e79d0e21675d2da48f02983c0e7b5c0 198 Gene3D G3DSA:3.40.50.140 111 170 6.9E-7 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS00120 2e79d0e21675d2da48f02983c0e7b5c0 198 Pfam PF02132 RecR protein 40 78 7.3E-18 T 06-07-2017 IPR023628 Recombination protein RecR, C4-type zinc finger GTHT12_RS00120 2e79d0e21675d2da48f02983c0e7b5c0 198 SUPERFAMILY SSF111304 1 198 4.45E-80 T 06-07-2017 IPR023627 Recombination protein RecR GTHT12_RS00120 2e79d0e21675d2da48f02983c0e7b5c0 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 112.604 T 06-07-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 GTHT12_RS00120 2e79d0e21675d2da48f02983c0e7b5c0 198 Pfam PF13662 Toprim domain 82 171 2.2E-27 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS00120 2e79d0e21675d2da48f02983c0e7b5c0 198 SMART SM00493 80 165 5.0E-18 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 Gene3D G3DSA:1.10.460.10 457 561 1.7E-63 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 Gene3D G3DSA:1.10.460.10 620 624 1.7E-63 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 Gene3D G3DSA:1.10.460.10 135 182 1.7E-63 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 SUPERFAMILY SSF56712 4 589 8.89E-202 T 06-07-2017 IPR023405 DNA topoisomerase, type IA, core domain GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 SMART SM00437 242 510 2.0E-128 T 06-07-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 Gene3D G3DSA:2.70.20.10 184 314 1.6E-34 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 Gene3D G3DSA:2.70.20.10 316 456 1.2E-37 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 Pfam PF01131 DNA topoisomerase 128 548 2.6E-137 T 06-07-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 473 487 8.4E-37 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 370 386 8.4E-37 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 8.4E-37 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 293 302 8.4E-37 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 8.4E-37 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 611 1.1E-265 T 06-07-2017 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 659 688 0.0012 T 06-07-2017 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 616 655 9.0E-14 T 06-07-2017 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 577 613 6.4E-16 T 06-07-2017 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 SMART SM00436 104 192 1.4E-53 T 06-07-2017 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 633 56.534 T 06-07-2017 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 279 302 - T 06-07-2017 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 Pfam PF01751 Toprim domain 5 113 7.9E-30 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 Gene3D G3DSA:3.40.50.140 1 134 2.0E-44 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 SMART SM00493 3 103 2.2E-32 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 Gene3D G3DSA:3.30.65.10 563 619 6.3E-21 T 06-07-2017 GTHT12_RS06290 85f31d6a278a7ec6d9b8bcdb267137ee 691 SUPERFAMILY SSF57783 574 613 1.31E-13 T 06-07-2017 GTHT12_RS12645 6ea7885af573d857d411417e8b8f5ecf 346 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 7 338 9.4E-112 T 06-07-2017 IPR011200 Uncharacterised conserved protein UCP012608 GTHT12_RS12645 6ea7885af573d857d411417e8b8f5ecf 346 PIRSF PIRSF012608 4 344 2.3E-106 T 06-07-2017 IPR011200 Uncharacterised conserved protein UCP012608 GTHT12_RS15585 5da7c85a0ef8264e5cd9fa13fb45fd5e 144 SUPERFAMILY SSF82649 2 143 1.13E-54 T 06-07-2017 GTHT12_RS15585 5da7c85a0ef8264e5cd9fa13fb45fd5e 144 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 7 141 9.3E-60 T 06-07-2017 GTHT12_RS15585 5da7c85a0ef8264e5cd9fa13fb45fd5e 144 Gene3D G3DSA:3.90.1010.10 9 143 1.8E-46 T 06-07-2017 GTHT12_RS15585 5da7c85a0ef8264e5cd9fa13fb45fd5e 144 Pfam PF01592 NifU-like N terminal domain 11 129 3.7E-35 T 06-07-2017 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 GTHT12_RS07355 5c7ca16fa8b0824b1e85185122c1b6ec 1256 Pfam PF13087 AAA domain 978 1189 3.5E-21 T 06-07-2017 GTHT12_RS07355 5c7ca16fa8b0824b1e85185122c1b6ec 1256 Pfam PF12705 PD-(D/E)XK nuclease superfamily 131 248 9.8E-5 T 06-07-2017 GTHT12_RS07355 5c7ca16fa8b0824b1e85185122c1b6ec 1256 Gene3D G3DSA:3.40.50.300 766 1021 4.7E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07355 5c7ca16fa8b0824b1e85185122c1b6ec 1256 Pfam PF13604 AAA domain 788 966 1.9E-12 T 06-07-2017 GTHT12_RS07355 5c7ca16fa8b0824b1e85185122c1b6ec 1256 SUPERFAMILY SSF52540 787 1213 1.53E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00225 0a223306d9e569b21567ab8ac0f99aba 293 SUPERFAMILY SSF53335 16 290 1.6E-76 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS00225 0a223306d9e569b21567ab8ac0f99aba 293 Pfam PF00398 Ribosomal RNA adenine dimethylase 20 280 8.8E-75 T 06-07-2017 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm GTHT12_RS00225 0a223306d9e569b21567ab8ac0f99aba 293 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 52 79 - T 06-07-2017 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 GTHT12_RS00225 0a223306d9e569b21567ab8ac0f99aba 293 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 20 287 1.2E-87 T 06-07-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 GTHT12_RS00225 0a223306d9e569b21567ab8ac0f99aba 293 Gene3D G3DSA:1.10.8.100 215 287 2.3E-25 T 06-07-2017 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201 GTHT12_RS00225 0a223306d9e569b21567ab8ac0f99aba 293 Gene3D G3DSA:3.40.50.150 5 214 5.5E-77 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS00225 0a223306d9e569b21567ab8ac0f99aba 293 SMART SM00650 36 212 9.6E-88 T 06-07-2017 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 GTHT12_RS00225 0a223306d9e569b21567ab8ac0f99aba 293 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 20 288 59.245 T 06-07-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 GTHT12_RS06700 0acb6fbae52446803381213447cc28f2 300 Gene3D G3DSA:1.10.260.40 3 83 9.6E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS06700 0acb6fbae52446803381213447cc28f2 300 SMART SM00530 8 69 5.3E-4 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GTHT12_RS06700 0acb6fbae52446803381213447cc28f2 300 SUPERFAMILY SSF47413 3 76 1.8E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS06700 0acb6fbae52446803381213447cc28f2 300 Pfam PF13413 Helix-turn-helix domain 8 69 7.5E-22 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS06700 0acb6fbae52446803381213447cc28f2 300 Pfam PF13464 Domain of unknown function (DUF4115) 220 281 2.7E-10 T 06-07-2017 IPR025194 Domain of unknown function DUF4115 GTHT12_RS15680 9638e6f847751a84b7dc7e8025ba2baa 305 SUPERFAMILY SSF51730 37 300 1.53E-77 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like GTHT12_RS15680 9638e6f847751a84b7dc7e8025ba2baa 305 Pfam PF01619 Proline dehydrogenase 44 298 4.0E-38 T 06-07-2017 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 GTHT12_RS15680 9638e6f847751a84b7dc7e8025ba2baa 305 PIRSF PIRSF000196 1 305 4.1E-137 T 06-07-2017 IPR008219 Proline dehydrogenase GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 GTHT12_RS15680 9638e6f847751a84b7dc7e8025ba2baa 305 Gene3D G3DSA:3.20.20.220 36 300 1.8E-75 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like GTHT12_RS07480 af1cc5271faf405240b12c14faa51579 245 Pfam PF00188 Cysteine-rich secretory protein family 130 242 1.7E-23 T 06-07-2017 IPR014044 CAP domain GTHT12_RS07480 af1cc5271faf405240b12c14faa51579 245 Gene3D G3DSA:3.40.33.10 121 237 5.6E-18 T 06-07-2017 IPR014044 CAP domain GTHT12_RS07480 af1cc5271faf405240b12c14faa51579 245 TIGRFAM TIGR02909 spore_YkwD: uncharacterized protein, YkwD family 122 243 7.0E-60 T 06-07-2017 IPR014258 CAP domain, YkwD-like GTHT12_RS07480 af1cc5271faf405240b12c14faa51579 245 SUPERFAMILY SSF55797 122 242 4.97E-28 T 06-07-2017 IPR014044 CAP domain GTHT12_RS06820 215d2d55cf7907b1eddf2858076bc662 357 Gene3D G3DSA:3.30.1540.10 220 289 1.1E-13 T 06-07-2017 GTHT12_RS06820 215d2d55cf7907b1eddf2858076bc662 357 SUPERFAMILY SSF89796 1 308 4.32E-95 T 06-07-2017 IPR023606 CoA-transferase family III domain GTHT12_RS06820 215d2d55cf7907b1eddf2858076bc662 357 Pfam PF02515 CoA-transferase family III 2 307 9.8E-88 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 GTHT12_RS06820 215d2d55cf7907b1eddf2858076bc662 357 Gene3D G3DSA:3.40.50.10540 290 309 1.5E-78 T 06-07-2017 IPR023606 CoA-transferase family III domain GTHT12_RS06820 215d2d55cf7907b1eddf2858076bc662 357 Gene3D G3DSA:3.40.50.10540 1 206 1.5E-78 T 06-07-2017 IPR023606 CoA-transferase family III domain GTHT12_RS18775 e3b94d264782a4ad3b6c0675758f6fea 80 Pfam PF00462 Glutaredoxin 3 50 9.6E-11 T 06-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 GTHT12_RS18775 e3b94d264782a4ad3b6c0675758f6fea 80 Gene3D G3DSA:3.40.30.10 1 74 2.8E-16 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS18775 e3b94d264782a4ad3b6c0675758f6fea 80 SUPERFAMILY SSF52833 1 73 1.55E-12 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS14790 b5b7af5f5f4e919414d296888b16185f 80 Gene3D G3DSA:2.40.240.20 1 77 6.9E-37 T 06-07-2017 GTHT12_RS14790 b5b7af5f5f4e919414d296888b16185f 80 Pfam PF10763 Protein of unknown function (DUF2584) 1 80 1.3E-38 T 06-07-2017 IPR019699 Protein of unknown function DUF2584 GTHT12_RS14790 b5b7af5f5f4e919414d296888b16185f 80 SUPERFAMILY SSF88697 1 80 1.64E-31 T 06-07-2017 IPR015947 PUA-like domain GTHT12_RS00975 c405517830946a776b1e4511e3deb060 292 Pfam PF00005 ABC transporter 20 150 9.0E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS00975 c405517830946a776b1e4511e3deb060 292 SMART SM00382 29 205 1.2E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS00975 c405517830946a776b1e4511e3deb060 292 SUPERFAMILY SSF52540 3 212 7.88E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00975 c405517830946a776b1e4511e3deb060 292 Gene3D G3DSA:3.40.50.300 3 217 1.0E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00975 c405517830946a776b1e4511e3deb060 292 ProSitePatterns PS00211 ABC transporters family signature. 123 137 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS17815 a137ef9de2639d589c4bff29ff1688f7 116 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 6 104 8.2E-22 T 06-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 GTHT12_RS17815 a137ef9de2639d589c4bff29ff1688f7 116 Pfam PF13466 STAS domain 21 99 1.8E-16 T 06-07-2017 IPR002645 STAS domain GTHT12_RS17815 a137ef9de2639d589c4bff29ff1688f7 116 Gene3D G3DSA:3.30.750.24 7 110 3.3E-26 T 06-07-2017 IPR002645 STAS domain GTHT12_RS17815 a137ef9de2639d589c4bff29ff1688f7 116 SUPERFAMILY SSF52091 8 110 4.58E-24 T 06-07-2017 IPR002645 STAS domain GTHT12_RS06985 c14f76717ed83476ff63639923df8f25 49 Hamap MF_00665 Small, acid-soluble spore protein O [sspO]. 1 49 21.927 T 06-07-2017 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 GTHT12_RS06985 c14f76717ed83476ff63639923df8f25 49 ProDom PD050103 O SPORE SMALL ACID-SOLUBLE SASP SPORULATION CAPSID COAT K SEQUENCING 3 37 7.0E-14 T 06-07-2017 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 GTHT12_RS06985 c14f76717ed83476ff63639923df8f25 49 TIGRFAM TIGR02864 spore_sspO: small, acid-soluble spore protein O 1 49 2.3E-28 T 06-07-2017 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 GTHT12_RS06985 c14f76717ed83476ff63639923df8f25 49 Pfam PF08175 Small acid-soluble spore protein O family 2 49 4.9E-28 T 06-07-2017 GTHT12_RS13405 0d996d5035bc08502416807eba522368 787 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 16 751 3.3E-261 T 06-07-2017 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 GTHT12_RS13405 0d996d5035bc08502416807eba522368 787 SUPERFAMILY SSF52540 337 734 9.72E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13405 0d996d5035bc08502416807eba522368 787 Gene3D G3DSA:3.40.50.300 670 737 3.5E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13405 0d996d5035bc08502416807eba522368 787 Pfam PF13604 AAA domain 343 550 7.0E-53 T 06-07-2017 GTHT12_RS13405 0d996d5035bc08502416807eba522368 787 Pfam PF13538 UvrD-like helicase C-terminal domain 678 726 2.5E-17 T 06-07-2017 IPR027785 UvrD-like helicase C-terminal domain GTHT12_RS13405 0d996d5035bc08502416807eba522368 787 Pfam PF14490 Helix-hairpin-helix containing domain 157 247 2.1E-30 T 06-07-2017 IPR029493 RecD helicase-like helix-hairpin-helix domain GTHT12_RS13405 0d996d5035bc08502416807eba522368 787 Gene3D G3DSA:3.40.50.300 299 536 2.2E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13405 0d996d5035bc08502416807eba522368 787 Pfam PF14520 Helix-hairpin-helix domain 107 153 0.0012 T 06-07-2017 GTHT12_RS13405 0d996d5035bc08502416807eba522368 787 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 12 769 29.902 T 06-07-2017 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 GTHT12_RS04155 46a5c2ef8019b20ec9c2ca841552e31b 235 Pfam PF04405 Domain of Unknown function (DUF542) 10 62 4.7E-21 T 06-07-2017 IPR019903 Repair of iron centres family GTHT12_RS04155 46a5c2ef8019b20ec9c2ca841552e31b 235 SUPERFAMILY SSF140683 2 65 8.76E-5 T 06-07-2017 GTHT12_RS04155 46a5c2ef8019b20ec9c2ca841552e31b 235 Gene3D G3DSA:1.20.120.520 69 231 8.8E-34 T 06-07-2017 GTHT12_RS04155 46a5c2ef8019b20ec9c2ca841552e31b 235 TIGRFAM TIGR03652 FeS_repair_RIC: iron-sulfur cluster repair di-iron protein 11 229 1.3E-88 T 06-07-2017 IPR019903 Repair of iron centres family GTHT12_RS04155 46a5c2ef8019b20ec9c2ca841552e31b 235 Pfam PF01814 Hemerythrin HHE cation binding domain 83 229 2.0E-24 T 06-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 GTHT12_RS12740 4f029af83f9a2b03459c5e3a18de00a1 554 Gene3D G3DSA:3.40.50.300 339 494 2.2E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12740 4f029af83f9a2b03459c5e3a18de00a1 554 Pfam PF00271 Helicase conserved C-terminal domain 353 459 3.6E-20 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS12740 4f029af83f9a2b03459c5e3a18de00a1 554 SUPERFAMILY SSF52540 12 258 6.9E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12740 4f029af83f9a2b03459c5e3a18de00a1 554 SMART SM00490 379 459 3.3E-21 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS12740 4f029af83f9a2b03459c5e3a18de00a1 554 SUPERFAMILY SSF52540 343 513 5.42E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12740 4f029af83f9a2b03459c5e3a18de00a1 554 SUPERFAMILY SSF52540 168 222 5.42E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12740 4f029af83f9a2b03459c5e3a18de00a1 554 Gene3D G3DSA:3.40.50.300 59 218 1.1E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12740 4f029af83f9a2b03459c5e3a18de00a1 554 Pfam PF00176 SNF2 family N-terminal domain 79 295 5.9E-33 T 06-07-2017 IPR000330 SNF2-related, N-terminal domain GO:0005524 GTHT12_RS12740 4f029af83f9a2b03459c5e3a18de00a1 554 SMART SM00487 56 232 1.3E-30 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain GTHT12_RS10985 02a3b9a09c7970619fcca27396d08232 520 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 1.1E-5 T 06-07-2017 GTHT12_RS10985 02a3b9a09c7970619fcca27396d08232 520 PRINTS PR01036 Tetracycline resistance protein TetB signature 73 95 1.1E-5 T 06-07-2017 GTHT12_RS10985 02a3b9a09c7970619fcca27396d08232 520 PRINTS PR01036 Tetracycline resistance protein TetB signature 299 323 1.1E-5 T 06-07-2017 GTHT12_RS10985 02a3b9a09c7970619fcca27396d08232 520 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 11 486 7.8E-82 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 GTHT12_RS10985 02a3b9a09c7970619fcca27396d08232 520 SUPERFAMILY SSF103473 467 496 3.53E-71 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS10985 02a3b9a09c7970619fcca27396d08232 520 SUPERFAMILY SSF103473 9 199 3.53E-71 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS10985 02a3b9a09c7970619fcca27396d08232 520 SUPERFAMILY SSF103473 246 416 3.53E-71 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS10985 02a3b9a09c7970619fcca27396d08232 520 Pfam PF07690 Major Facilitator Superfamily 15 406 1.1E-54 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS10985 02a3b9a09c7970619fcca27396d08232 520 Gene3D G3DSA:1.20.1250.20 12 193 2.6E-38 T 06-07-2017 GTHT12_RS10985 02a3b9a09c7970619fcca27396d08232 520 Gene3D G3DSA:1.20.1250.20 260 417 6.0E-20 T 06-07-2017 GTHT12_RS10985 02a3b9a09c7970619fcca27396d08232 520 Gene3D G3DSA:1.20.1250.20 468 495 6.0E-20 T 06-07-2017 GTHT12_RS07940 60a27f3bc80415139fea26b5189fb136 645 Pfam PF13307 Helicase C-terminal domain 493 621 5.2E-20 T 06-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 GTHT12_RS07940 60a27f3bc80415139fea26b5189fb136 645 Gene3D G3DSA:3.40.50.300 482 632 3.2E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07940 60a27f3bc80415139fea26b5189fb136 645 SMART SM00491 505 627 1.7E-6 T 06-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 GTHT12_RS07940 60a27f3bc80415139fea26b5189fb136 645 Gene3D G3DSA:3.40.50.300 222 275 2.0E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07940 60a27f3bc80415139fea26b5189fb136 645 Gene3D G3DSA:3.40.50.300 37 139 2.0E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07940 60a27f3bc80415139fea26b5189fb136 645 Gene3D G3DSA:3.40.50.300 411 436 2.0E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07940 60a27f3bc80415139fea26b5189fb136 645 SUPERFAMILY SSF52540 203 281 4.1E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07940 60a27f3bc80415139fea26b5189fb136 645 SUPERFAMILY SSF52540 52 107 4.1E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07940 60a27f3bc80415139fea26b5189fb136 645 SUPERFAMILY SSF52540 422 624 4.1E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS15860 f3f6b2ca5ee1d6e1aaaf1f37e36b0b8e 246 SUPERFAMILY SSF53474 10 245 2.49E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS15860 f3f6b2ca5ee1d6e1aaaf1f37e36b0b8e 246 Pfam PF12146 Serine aminopeptidase, S33 16 228 6.1E-17 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 GTHT12_RS15860 f3f6b2ca5ee1d6e1aaaf1f37e36b0b8e 246 PIRSF PIRSF017388 1 246 4.5E-100 T 06-07-2017 IPR012354 Esterase/lipase GO:0052689 GTHT12_RS15860 f3f6b2ca5ee1d6e1aaaf1f37e36b0b8e 246 Gene3D G3DSA:3.40.50.1820 13 244 1.1E-63 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS08155 ae1f849b4393752bec0e1283b8b97792 141 Gene3D G3DSA:1.20.58.340 33 109 5.6E-27 T 06-07-2017 GTHT12_RS08155 ae1f849b4393752bec0e1283b8b97792 141 SUPERFAMILY SSF144083 45 106 5.36E-20 T 06-07-2017 GTHT12_RS08155 ae1f849b4393752bec0e1283b8b97792 141 Pfam PF01544 CorA-like Mg2+ transporter protein 2 105 8.8E-31 T 06-07-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 GTHT12_RS12305 7a44655d904c751644aee339f3a0d44a 494 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 176 182 - T 06-07-2017 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GTHT12_RS12305 7a44655d904c751644aee339f3a0d44a 494 Gene3D G3DSA:3.30.360.10 186 486 3.4E-121 T 06-07-2017 GTHT12_RS12305 7a44655d904c751644aee339f3a0d44a 494 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 4 488 89.391 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GTHT12_RS12305 7a44655d904c751644aee339f3a0d44a 494 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 189 486 6.2E-118 T 06-07-2017 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GTHT12_RS12305 7a44655d904c751644aee339f3a0d44a 494 Gene3D G3DSA:3.40.50.720 4 185 2.5E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS12305 7a44655d904c751644aee339f3a0d44a 494 PIRSF PIRSF000110 2 490 4.7E-193 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GTHT12_RS12305 7a44655d904c751644aee339f3a0d44a 494 SUPERFAMILY SSF51735 4 189 3.15E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS12305 7a44655d904c751644aee339f3a0d44a 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 236 252 5.5E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GTHT12_RS12305 7a44655d904c751644aee339f3a0d44a 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 142 155 5.5E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GTHT12_RS12305 7a44655d904c751644aee339f3a0d44a 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 218 235 5.5E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GTHT12_RS12305 7a44655d904c751644aee339f3a0d44a 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 166 194 5.5E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GTHT12_RS12305 7a44655d904c751644aee339f3a0d44a 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 327 353 5.5E-48 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GTHT12_RS12305 7a44655d904c751644aee339f3a0d44a 494 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 4 487 1.3E-203 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GTHT12_RS12305 7a44655d904c751644aee339f3a0d44a 494 SUPERFAMILY SSF55347 181 487 6.54E-118 T 06-07-2017 GTHT12_RS12305 7a44655d904c751644aee339f3a0d44a 494 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 8 186 7.9E-63 T 06-07-2017 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 GTHT12_RS12410 dd8ca7f9d1de9c131c8b6767d5f173f3 224 SUPERFAMILY SSF52172 3 175 6.88E-43 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS12410 dd8ca7f9d1de9c131c8b6767d5f173f3 224 Gene3D G3DSA:1.10.10.10 127 223 7.3E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12410 dd8ca7f9d1de9c131c8b6767d5f173f3 224 Gene3D G3DSA:3.40.50.2300 3 125 2.5E-40 T 06-07-2017 GTHT12_RS12410 dd8ca7f9d1de9c131c8b6767d5f173f3 224 SMART SM00862 149 222 2.2E-27 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS12410 dd8ca7f9d1de9c131c8b6767d5f173f3 224 Pfam PF00072 Response regulator receiver domain 6 114 3.9E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS12410 dd8ca7f9d1de9c131c8b6767d5f173f3 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 222 1.0E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS12410 dd8ca7f9d1de9c131c8b6767d5f173f3 224 SMART SM00448 4 114 1.2E-41 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS15215 fbe4344ee56c8b2f6f527e52ab4cebb0 272 ProDom PD119415 TRANSGLUTAMINASE TRANSFERASE ACYLTRANSFERASE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE TGASE SPORULATION TGL 22 246 5.0E-99 T 06-07-2017 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 GTHT12_RS15215 fbe4344ee56c8b2f6f527e52ab4cebb0 272 Hamap MF_00727 Protein-glutamine gamma-glutamyltransferase [tgl]. 3 246 43.487 T 06-07-2017 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 GTHT12_RS15345 eded48c56d430d77fc527671a02bd76c 158 Pfam PF01899 Na+/H+ ion antiporter subunit 8 156 5.9E-43 T 06-07-2017 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 GTHT12_RS15345 eded48c56d430d77fc527671a02bd76c 158 PIRSF PIRSF019239 1 158 4.9E-46 T 06-07-2017 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 GTHT12_RS15985 c352cbe59548ea0c72c4893c74920b3e 213 Pfam PF00117 Glutamine amidotransferase class-I 6 195 1.4E-22 T 06-07-2017 IPR017926 Glutamine amidotransferase GTHT12_RS15985 c352cbe59548ea0c72c4893c74920b3e 213 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 206 37.416 T 06-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 GTHT12_RS15985 c352cbe59548ea0c72c4893c74920b3e 213 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 204 4.2E-70 T 06-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 GTHT12_RS15985 c352cbe59548ea0c72c4893c74920b3e 213 SUPERFAMILY SSF52317 2 207 5.26E-59 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS15985 c352cbe59548ea0c72c4893c74920b3e 213 PIRSF PIRSF000495 2 209 1.8E-73 T 06-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 GTHT12_RS15985 c352cbe59548ea0c72c4893c74920b3e 213 Gene3D G3DSA:3.40.50.880 1 209 4.1E-80 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS01760 07d1da4c93344229408799f90effb401 472 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 361 469 6.9E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS01760 07d1da4c93344229408799f90effb401 472 SUPERFAMILY SSF55874 302 468 3.54E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS01760 07d1da4c93344229408799f90effb401 472 SMART SM00387 360 471 1.4E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS01760 07d1da4c93344229408799f90effb401 472 Pfam PF00512 His Kinase A (phospho-acceptor) domain 248 311 1.1E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS01760 07d1da4c93344229408799f90effb401 472 Gene3D G3DSA:1.10.287.130 236 306 7.1E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS01760 07d1da4c93344229408799f90effb401 472 Gene3D G3DSA:3.30.565.10 316 467 3.7E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS01760 07d1da4c93344229408799f90effb401 472 SUPERFAMILY SSF47384 229 314 1.55E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS01760 07d1da4c93344229408799f90effb401 472 SMART SM00388 246 313 2.2E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS01760 07d1da4c93344229408799f90effb401 472 SMART SM00304 186 238 0.0057 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS01760 07d1da4c93344229408799f90effb401 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 449 1.2E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS01760 07d1da4c93344229408799f90effb401 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 414 1.2E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS01760 07d1da4c93344229408799f90effb401 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 428 1.2E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS12585 d9aef188a2a683d6ce9a1f0210f05520 68 TIGRFAM TIGR02848 spore_III_AC: stage III sporulation protein AC 3 66 3.7E-30 T 06-07-2017 IPR009570 Stage III sporulation protein AC GTHT12_RS12585 d9aef188a2a683d6ce9a1f0210f05520 68 Pfam PF06686 Stage III sporulation protein AC/AD protein family 8 62 3.8E-17 T 06-07-2017 IPR025664 Stage III sporulation protein AC/AD family GTHT12_RS13235 4f6ee811cc173dc74534a4fa1a7c61c4 171 Pfam PF00702 haloacid dehalogenase-like hydrolase 36 127 5.0E-12 T 06-07-2017 GTHT12_RS13235 4f6ee811cc173dc74534a4fa1a7c61c4 171 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 58 130 4.0E-8 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 GTHT12_RS13235 4f6ee811cc173dc74534a4fa1a7c61c4 171 SUPERFAMILY SSF56784 15 147 6.49E-27 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS13235 4f6ee811cc173dc74534a4fa1a7c61c4 171 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 28 138 2.4E-24 T 06-07-2017 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 GTHT12_RS13235 4f6ee811cc173dc74534a4fa1a7c61c4 171 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 4 165 1.9E-54 T 06-07-2017 IPR010021 HAD-superfamily phosphatase, YqeG-like GTHT12_RS13235 4f6ee811cc173dc74534a4fa1a7c61c4 171 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 56 136 1.4E-7 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 GTHT12_RS13235 4f6ee811cc173dc74534a4fa1a7c61c4 171 Gene3D G3DSA:3.40.50.1000 12 154 6.1E-28 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS03325 fdbd848d29628001a9fa1a12af945570 325 Gene3D G3DSA:3.40.50.2300 59 167 1.2E-34 T 06-07-2017 GTHT12_RS03325 fdbd848d29628001a9fa1a12af945570 325 Pfam PF13377 Periplasmic binding protein-like domain 167 324 1.1E-30 T 06-07-2017 GTHT12_RS03325 fdbd848d29628001a9fa1a12af945570 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 1.2E-5 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS03325 fdbd848d29628001a9fa1a12af945570 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 1.2E-5 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS03325 fdbd848d29628001a9fa1a12af945570 325 SUPERFAMILY SSF53822 62 324 3.62E-63 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS03325 fdbd848d29628001a9fa1a12af945570 325 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 3.3E-18 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS03325 fdbd848d29628001a9fa1a12af945570 325 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 06-07-2017 GTHT12_RS03325 fdbd848d29628001a9fa1a12af945570 325 SUPERFAMILY SSF47413 2 59 1.13E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS03325 fdbd848d29628001a9fa1a12af945570 325 Gene3D G3DSA:1.10.260.40 2 58 2.3E-23 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS03325 fdbd848d29628001a9fa1a12af945570 325 Gene3D G3DSA:3.40.50.2300 168 324 3.0E-45 T 06-07-2017 GTHT12_RS03325 fdbd848d29628001a9fa1a12af945570 325 SMART SM00354 1 71 4.6E-27 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS18690 1a5be21b0895b737f3481be2657e7141 324 Gene3D G3DSA:3.40.50.2300 171 301 1.4E-34 T 06-07-2017 GTHT12_RS18690 1a5be21b0895b737f3481be2657e7141 324 SMART SM00354 3 73 3.8E-36 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS18690 1a5be21b0895b737f3481be2657e7141 324 Gene3D G3DSA:1.10.260.40 5 55 5.2E-27 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS18690 1a5be21b0895b737f3481be2657e7141 324 SUPERFAMILY SSF47413 2 62 1.84E-20 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS18690 1a5be21b0895b737f3481be2657e7141 324 SUPERFAMILY SSF53822 60 318 4.91E-67 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS18690 1a5be21b0895b737f3481be2657e7141 324 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 15 25 2.9E-5 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS18690 1a5be21b0895b737f3481be2657e7141 324 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 5 15 2.9E-5 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS18690 1a5be21b0895b737f3481be2657e7141 324 Pfam PF13377 Periplasmic binding protein-like domain 166 322 6.3E-24 T 06-07-2017 GTHT12_RS18690 1a5be21b0895b737f3481be2657e7141 324 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 06-07-2017 GTHT12_RS18690 1a5be21b0895b737f3481be2657e7141 324 Gene3D G3DSA:3.40.50.2300 56 170 2.5E-46 T 06-07-2017 GTHT12_RS18690 1a5be21b0895b737f3481be2657e7141 324 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 1.6E-22 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS16565 344cfaf9bd9c7d9caecfe850d2c83035 441 Gene3D G3DSA:4.10.320.10 115 161 2.8E-15 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS16565 344cfaf9bd9c7d9caecfe850d2c83035 441 Pfam PF00364 Biotin-requiring enzyme 6 78 7.1E-22 T 06-07-2017 IPR000089 Biotin/lipoyl attachment GTHT12_RS16565 344cfaf9bd9c7d9caecfe850d2c83035 441 SUPERFAMILY SSF52777 200 438 6.67E-86 T 06-07-2017 GTHT12_RS16565 344cfaf9bd9c7d9caecfe850d2c83035 441 SUPERFAMILY SSF51230 3 87 1.09E-25 T 06-07-2017 IPR011053 Single hybrid motif GTHT12_RS16565 344cfaf9bd9c7d9caecfe850d2c83035 441 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 208 438 1.6E-86 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS16565 344cfaf9bd9c7d9caecfe850d2c83035 441 Gene3D G3DSA:2.40.50.100 4 92 1.1E-25 T 06-07-2017 GTHT12_RS16565 344cfaf9bd9c7d9caecfe850d2c83035 441 SUPERFAMILY SSF47005 113 156 1.96E-10 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS16565 344cfaf9bd9c7d9caecfe850d2c83035 441 Gene3D G3DSA:3.30.559.10 199 438 1.8E-88 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 GTHT12_RS16565 344cfaf9bd9c7d9caecfe850d2c83035 441 Pfam PF02817 e3 binding domain 117 152 7.7E-11 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 GTHT12_RS15475 71102662f4368e71a15391d1f6bb22b4 333 SUPERFAMILY SSF56112 2 313 1.9E-17 T 06-07-2017 IPR011009 Protein kinase-like domain GTHT12_RS15475 71102662f4368e71a15391d1f6bb22b4 333 TIGRFAM TIGR02905 spore_yutH: spore coat protein YutH 2 312 7.7E-134 T 06-07-2017 IPR014254 Spore coat protein YutH GTHT12_RS15475 71102662f4368e71a15391d1f6bb22b4 333 Gene3D G3DSA:3.90.1200.10 95 309 2.3E-37 T 06-07-2017 GTHT12_RS18395 a991e519345b161436ec114774364e08 146 Pfam PF04002 RadC-like JAB domain 23 143 8.3E-42 T 06-07-2017 IPR025657 RadC-like JAB domain GTHT12_RS18395 a991e519345b161436ec114774364e08 146 SUPERFAMILY SSF102712 72 112 8.24E-5 T 06-07-2017 GTHT12_RS18395 a991e519345b161436ec114774364e08 146 Gene3D G3DSA:3.40.140.10 20 144 3.7E-45 T 06-07-2017 GTHT12_RS14680 91fd959b077c98162cc5ebadcffa2d3a 726 TIGRFAM TIGR02104 pulA_typeI: pullulanase, type I 96 692 1.6E-263 T 06-07-2017 IPR011840 Pullulanase, type I GTHT12_RS14680 91fd959b077c98162cc5ebadcffa2d3a 726 SUPERFAMILY SSF51445 198 623 1.02E-123 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS14680 91fd959b077c98162cc5ebadcffa2d3a 726 SMART SM00642 256 616 2.6E-7 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GTHT12_RS14680 91fd959b077c98162cc5ebadcffa2d3a 726 SUPERFAMILY SSF81296 101 203 5.0E-23 T 06-07-2017 IPR014756 Immunoglobulin E-set GTHT12_RS14680 91fd959b077c98162cc5ebadcffa2d3a 726 Gene3D G3DSA:2.60.40.10 104 198 6.7E-21 T 06-07-2017 IPR013783 Immunoglobulin-like fold GTHT12_RS14680 91fd959b077c98162cc5ebadcffa2d3a 726 Pfam PF00128 Alpha amylase, catalytic domain 257 351 9.9E-8 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GTHT12_RS14680 91fd959b077c98162cc5ebadcffa2d3a 726 Gene3D G3DSA:3.20.20.80 212 624 3.8E-98 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS14680 91fd959b077c98162cc5ebadcffa2d3a 726 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 106 184 4.0E-17 T 06-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 GTHT12_RS04020 01248025750ae1ecbe0c6fefa246e6f8 268 Gene3D G3DSA:3.40.50.1000 1 73 2.1E-55 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS04020 01248025750ae1ecbe0c6fefa246e6f8 268 Gene3D G3DSA:3.40.50.1000 172 266 2.1E-55 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS04020 01248025750ae1ecbe0c6fefa246e6f8 268 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 235 3.6E-21 T 06-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 GTHT12_RS04020 01248025750ae1ecbe0c6fefa246e6f8 268 SUPERFAMILY SSF56784 1 266 7.63E-71 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS04020 01248025750ae1ecbe0c6fefa246e6f8 268 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 261 1.8E-64 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS04020 01248025750ae1ecbe0c6fefa246e6f8 268 Gene3D G3DSA:3.30.1240.10 86 171 7.7E-4 T 06-07-2017 GTHT12_RS04020 01248025750ae1ecbe0c6fefa246e6f8 268 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 262 2.5E-54 T 06-07-2017 IPR000150 Cof protein GO:0016787 GTHT12_RS09730 eea27ad0b92082aec5c0f6b7dbaf1814 284 Pfam PF00149 Calcineurin-like phosphoesterase 45 208 1.9E-10 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 GTHT12_RS09730 eea27ad0b92082aec5c0f6b7dbaf1814 284 Gene3D G3DSA:3.60.21.10 45 218 9.3E-24 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like GTHT12_RS09730 eea27ad0b92082aec5c0f6b7dbaf1814 284 SUPERFAMILY SSF56300 45 270 3.04E-32 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like GTHT12_RS04175 04f92166b6e286de0f204f0b66a6ca7a 155 SUPERFAMILY SSF54690 5 138 5.1E-48 T 06-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 GTHT12_RS04175 04f92166b6e286de0f204f0b66a6ca7a 155 Gene3D G3DSA:3.90.1170.40 3 140 1.3E-51 T 06-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 GTHT12_RS04175 04f92166b6e286de0f204f0b66a6ca7a 155 Pfam PF02391 MoaE protein 8 119 1.7E-39 T 06-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 GTHT12_RS11280 5b1fd78f3b6a3db6257c6f207dbae62f 925 SUPERFAMILY SSF48452 56 179 1.22E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS11280 5b1fd78f3b6a3db6257c6f207dbae62f 925 Gene3D G3DSA:1.25.40.10 59 179 1.4E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS11280 5b1fd78f3b6a3db6257c6f207dbae62f 925 SMART SM00028 88 121 8.2 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS11280 5b1fd78f3b6a3db6257c6f207dbae62f 925 SMART SM00028 123 156 36.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS11405 6ad86eca8279ecf04820a6b5c8649423 729 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 648 722 2.8E-24 T 06-07-2017 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 GTHT12_RS11405 6ad86eca8279ecf04820a6b5c8649423 729 SUPERFAMILY SSF51445 325 666 4.96E-116 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS11405 6ad86eca8279ecf04820a6b5c8649423 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 408 430 1.3E-64 T 06-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 GTHT12_RS11405 6ad86eca8279ecf04820a6b5c8649423 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 241 256 1.3E-64 T 06-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 GTHT12_RS11405 6ad86eca8279ecf04820a6b5c8649423 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 520 536 1.3E-64 T 06-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 GTHT12_RS11405 6ad86eca8279ecf04820a6b5c8649423 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 358 373 1.3E-64 T 06-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 GTHT12_RS11405 6ad86eca8279ecf04820a6b5c8649423 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 292 312 1.3E-64 T 06-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 GTHT12_RS11405 6ad86eca8279ecf04820a6b5c8649423 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 466 481 1.3E-64 T 06-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 GTHT12_RS11405 6ad86eca8279ecf04820a6b5c8649423 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 545 561 1.3E-64 T 06-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 GTHT12_RS11405 6ad86eca8279ecf04820a6b5c8649423 729 PRINTS PR00743 Glycosyl hydrolase family 36 signature 330 344 1.3E-64 T 06-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 GTHT12_RS11405 6ad86eca8279ecf04820a6b5c8649423 729 Pfam PF02065 Melibiase 289 635 2.9E-178 T 06-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 GTHT12_RS11405 6ad86eca8279ecf04820a6b5c8649423 729 Gene3D G3DSA:3.20.20.70 325 632 1.3E-51 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS11405 6ad86eca8279ecf04820a6b5c8649423 729 PIRSF PIRSF005536 1 727 0.0 T 06-07-2017 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 GTHT12_RS11405 6ad86eca8279ecf04820a6b5c8649423 729 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 29 285 7.9E-98 T 06-07-2017 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 GTHT12_RS11405 6ad86eca8279ecf04820a6b5c8649423 729 ProSitePatterns PS00512 Alpha-galactosidase signature. 359 374 - T 06-07-2017 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 GTHT12_RS06420 1260a5460eb0eb751a5edf01290761f5 360 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 14 358 2.8E-127 T 06-07-2017 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 GTHT12_RS06420 1260a5460eb0eb751a5edf01290761f5 360 Gene3D G3DSA:3.40.1690.10 224 358 5.7E-61 T 06-07-2017 IPR029025 Type III secretion system substrate exporter, C-terminal GTHT12_RS06420 1260a5460eb0eb751a5edf01290761f5 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 16 38 9.8E-40 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 GTHT12_RS06420 1260a5460eb0eb751a5edf01290761f5 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 278 293 9.8E-40 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 GTHT12_RS06420 1260a5460eb0eb751a5edf01290761f5 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 214 232 9.8E-40 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 GTHT12_RS06420 1260a5460eb0eb751a5edf01290761f5 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 308 329 9.8E-40 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 GTHT12_RS06420 1260a5460eb0eb751a5edf01290761f5 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 234 251 9.8E-40 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 GTHT12_RS06420 1260a5460eb0eb751a5edf01290761f5 360 SUPERFAMILY SSF160544 250 357 7.06E-43 T 06-07-2017 IPR029025 Type III secretion system substrate exporter, C-terminal GTHT12_RS06420 1260a5460eb0eb751a5edf01290761f5 360 Pfam PF01312 FlhB HrpN YscU SpaS Family 13 353 7.9E-130 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 GTHT12_RS12035 b3db1bb6a9ec45bdb907755449251823 174 SUPERFAMILY SSF52833 10 171 3.94E-45 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS12035 b3db1bb6a9ec45bdb907755449251823 174 Hamap MF_01319 Thiol-disulfide oxidoreductase ResA [resA]. 1 174 46.899 T 06-07-2017 IPR023555 Thiol-disulphide oxidoreductase ResA GO:0005886|GO:0015036|GO:0017004 GTHT12_RS12035 b3db1bb6a9ec45bdb907755449251823 174 Gene3D G3DSA:3.40.30.10 11 172 1.5E-54 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS12035 b3db1bb6a9ec45bdb907755449251823 174 Pfam PF00578 AhpC/TSA family 38 154 3.3E-36 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GTHT12_RS03290 e96e840c4433913b40e14179878245c7 288 Pfam PF12671 Putative amidase domain 128 281 6.4E-42 T 06-07-2017 IPR024301 Putative amidase domain GTHT12_RS03290 e96e840c4433913b40e14179878245c7 288 Gene3D G3DSA:3.90.1720.10 148 268 2.9E-4 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain GTHT12_RS05385 d765b3d6c9e17ee5bba30b86d4205f55 658 SMART SM00304 300 352 6.3E-14 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS05385 d765b3d6c9e17ee5bba30b86d4205f55 658 SUPERFAMILY SSF103190 89 190 2.88E-12 T 06-07-2017 IPR029151 Periplasmic sensor domain-like GTHT12_RS05385 d765b3d6c9e17ee5bba30b86d4205f55 658 SUPERFAMILY SSF58104 320 354 1.29E-66 T 06-07-2017 GTHT12_RS05385 d765b3d6c9e17ee5bba30b86d4205f55 658 SUPERFAMILY SSF58104 387 656 1.29E-66 T 06-07-2017 GTHT12_RS05385 d765b3d6c9e17ee5bba30b86d4205f55 658 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 508 537 8.3E-19 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 GTHT12_RS05385 d765b3d6c9e17ee5bba30b86d4205f55 658 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 405 434 8.3E-19 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 GTHT12_RS05385 d765b3d6c9e17ee5bba30b86d4205f55 658 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 479 506 8.3E-19 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 GTHT12_RS05385 d765b3d6c9e17ee5bba30b86d4205f55 658 Pfam PF02743 Cache domain 41 262 2.1E-32 T 06-07-2017 IPR033479 Double Cache domain 1 GTHT12_RS05385 d765b3d6c9e17ee5bba30b86d4205f55 658 Gene3D G3DSA:3.30.450.20 81 180 3.1E-29 T 06-07-2017 GTHT12_RS05385 d765b3d6c9e17ee5bba30b86d4205f55 658 SMART SM00283 381 656 6.6E-65 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 GTHT12_RS05385 d765b3d6c9e17ee5bba30b86d4205f55 658 Gene3D G3DSA:1.10.287.950 396 612 1.8E-46 T 06-07-2017 GTHT12_RS05385 d765b3d6c9e17ee5bba30b86d4205f55 658 Pfam PF00672 HAMP domain 281 347 4.4E-18 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS05385 d765b3d6c9e17ee5bba30b86d4205f55 658 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 450 631 4.4E-39 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 GTHT12_RS10735 9a04ad922bb1a6c8fb07d875920e8a63 183 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 120 8.1E-7 T 06-07-2017 IPR001451 Hexapeptide repeat GTHT12_RS10735 9a04ad922bb1a6c8fb07d875920e8a63 183 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 44 2.6E-6 T 06-07-2017 IPR001451 Hexapeptide repeat GTHT12_RS10735 9a04ad922bb1a6c8fb07d875920e8a63 183 Gene3D G3DSA:2.160.10.10 3 168 1.1E-49 T 06-07-2017 GTHT12_RS10735 9a04ad922bb1a6c8fb07d875920e8a63 183 SUPERFAMILY SSF51161 2 168 2.91E-49 T 06-07-2017 IPR011004 Trimeric LpxA-like GTHT12_RS13665 fd6dd72c50525f5e4617b0c91938ce74 288 Pfam PF04085 rod shape-determining protein MreC 123 274 1.8E-44 T 06-07-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 GTHT12_RS13665 fd6dd72c50525f5e4617b0c91938ce74 288 PIRSF PIRSF038471 1 287 4.7E-69 T 06-07-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 GTHT12_RS13665 fd6dd72c50525f5e4617b0c91938ce74 288 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 7 285 2.8E-65 T 06-07-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 GTHT12_RS10125 bd1b1131f3165462d6b7fe871d507fe5 318 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 297 1.1E-17 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 GTHT12_RS10125 bd1b1131f3165462d6b7fe871d507fe5 318 Pfam PF00005 ABC transporter 27 178 3.2E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS10125 bd1b1131f3165462d6b7fe871d507fe5 318 SMART SM00382 35 275 3.0E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS10125 bd1b1131f3165462d6b7fe871d507fe5 318 SUPERFAMILY SSF52540 5 250 5.08E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10125 bd1b1131f3165462d6b7fe871d507fe5 318 Gene3D G3DSA:3.40.50.300 3 253 8.3E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10125 bd1b1131f3165462d6b7fe871d507fe5 318 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 229 317 1.5E-27 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 GTHT12_RS10125 bd1b1131f3165462d6b7fe871d507fe5 318 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS04135 8e6e3f2ea81388def0bd6155b0e348d1 230 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 2 224 9.7E-71 T 06-07-2017 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 GTHT12_RS04135 8e6e3f2ea81388def0bd6155b0e348d1 230 Pfam PF02665 Nitrate reductase gamma subunit 5 224 1.1E-85 T 06-07-2017 IPR023234 NarG-like domain GTHT12_RS04135 8e6e3f2ea81388def0bd6155b0e348d1 230 Gene3D G3DSA:1.20.950.20 2 217 1.6E-73 T 06-07-2017 GTHT12_RS04135 8e6e3f2ea81388def0bd6155b0e348d1 230 SUPERFAMILY SSF103501 1 225 1.44E-68 T 06-07-2017 IPR023234 NarG-like domain GTHT12_RS10345 eeb0f577d6c63e0ce3507349e6a6f1bc 515 Gene3D G3DSA:3.30.420.40 3 251 2.6E-78 T 06-07-2017 GTHT12_RS10345 eeb0f577d6c63e0ce3507349e6a6f1bc 515 PIRSF PIRSF000538 5 505 2.0E-157 T 06-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 GTHT12_RS10345 eeb0f577d6c63e0ce3507349e6a6f1bc 515 TIGRFAM TIGR01312 XylB: xylulokinase 9 497 2.9E-116 T 06-07-2017 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 GTHT12_RS10345 eeb0f577d6c63e0ce3507349e6a6f1bc 515 Gene3D G3DSA:3.30.420.40 254 501 6.1E-65 T 06-07-2017 GTHT12_RS10345 eeb0f577d6c63e0ce3507349e6a6f1bc 515 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 455 1.8E-41 T 06-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 GTHT12_RS10345 eeb0f577d6c63e0ce3507349e6a6f1bc 515 TIGRFAM TIGR01314 gntK_FGGY: gluconate kinase 8 511 5.5E-196 T 06-07-2017 IPR006002 Gluconate kinase GO:0019521|GO:0046316 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 GTHT12_RS10345 eeb0f577d6c63e0ce3507349e6a6f1bc 515 SUPERFAMILY SSF53067 253 501 3.79E-70 T 06-07-2017 GTHT12_RS10345 eeb0f577d6c63e0ce3507349e6a6f1bc 515 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 251 2.3E-76 T 06-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 GTHT12_RS10345 eeb0f577d6c63e0ce3507349e6a6f1bc 515 SUPERFAMILY SSF53067 7 254 5.59E-77 T 06-07-2017 GTHT12_RS10345 eeb0f577d6c63e0ce3507349e6a6f1bc 515 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 136 148 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 GTHT12_RS10345 eeb0f577d6c63e0ce3507349e6a6f1bc 515 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 368 388 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 GTHT12_RS14780 50790cd80a416113ede840ad586afe96 404 Pfam PF02772 S-adenosylmethionine synthetase, central domain 128 245 1.8E-50 T 06-07-2017 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GTHT12_RS14780 50790cd80a416113ede840ad586afe96 404 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 273 281 - T 06-07-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GTHT12_RS14780 50790cd80a416113ede840ad586afe96 404 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 397 60.908 T 06-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GTHT12_RS14780 50790cd80a416113ede840ad586afe96 404 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 395 8.8E-190 T 06-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GTHT12_RS14780 50790cd80a416113ede840ad586afe96 404 PIRSF PIRSF000497 1 398 6.3E-181 T 06-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GTHT12_RS14780 50790cd80a416113ede840ad586afe96 404 SUPERFAMILY SSF55973 125 246 2.43E-53 T 06-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GTHT12_RS14780 50790cd80a416113ede840ad586afe96 404 SUPERFAMILY SSF55973 247 395 1.88E-71 T 06-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GTHT12_RS14780 50790cd80a416113ede840ad586afe96 404 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 129 139 - T 06-07-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GTHT12_RS14780 50790cd80a416113ede840ad586afe96 404 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 103 8.3E-45 T 06-07-2017 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GTHT12_RS14780 50790cd80a416113ede840ad586afe96 404 Gene3D G3DSA:3.30.300.10 149 247 1.2E-49 T 06-07-2017 GTHT12_RS14780 50790cd80a416113ede840ad586afe96 404 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 247 386 2.4E-71 T 06-07-2017 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GTHT12_RS14780 50790cd80a416113ede840ad586afe96 404 SUPERFAMILY SSF55973 5 111 1.33E-48 T 06-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 GTHT12_RS14780 50790cd80a416113ede840ad586afe96 404 Gene3D G3DSA:3.30.300.10 13 148 2.0E-49 T 06-07-2017 GTHT12_RS14780 50790cd80a416113ede840ad586afe96 404 Gene3D G3DSA:3.30.300.10 258 397 2.5E-71 T 06-07-2017 GTHT12_RS00065 fcf90a01b905cae89cf1ffc2cba574dc 328 Pfam PF14175 YaaC-like Protein 11 317 6.2E-118 T 06-07-2017 IPR026988 YaaC-like protein GTHT12_RS07715 dd17b0377d716995fc30211b10b91860 233 SUPERFAMILY SSF50891 91 221 1.37E-51 T 06-07-2017 IPR029000 Cyclophilin-like domain GTHT12_RS07715 dd17b0377d716995fc30211b10b91860 233 Gene3D G3DSA:3.30.1360.40 4 77 8.1E-17 T 06-07-2017 IPR024946 Arginine repressor C-terminal-like domain GTHT12_RS07715 dd17b0377d716995fc30211b10b91860 233 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 9 213 2.7E-74 T 06-07-2017 IPR010016 KipI family GTHT12_RS07715 dd17b0377d716995fc30211b10b91860 233 SMART SM00796 3 205 1.4E-101 T 06-07-2017 IPR003833 Carboxyltransferase domain, subdomain C and D GTHT12_RS07715 dd17b0377d716995fc30211b10b91860 233 Pfam PF02682 Allophanate hydrolase subunit 1 6 205 1.5E-76 T 06-07-2017 IPR003833 Carboxyltransferase domain, subdomain C and D GTHT12_RS07715 dd17b0377d716995fc30211b10b91860 233 SUPERFAMILY SSF160467 5 96 6.41E-16 T 06-07-2017 GTHT12_RS07715 dd17b0377d716995fc30211b10b91860 233 Gene3D G3DSA:2.40.100.10 91 228 5.4E-58 T 06-07-2017 IPR029000 Cyclophilin-like domain GTHT12_RS00915 75ee604559d20bdf2d9ca7d77c2598a6 299 PIRSF PIRSF036979 2 295 5.9E-40 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 GTHT12_RS00915 75ee604559d20bdf2d9ca7d77c2598a6 299 Gene3D G3DSA:3.40.800.10 3 295 2.3E-101 T 06-07-2017 IPR023696 Ureohydrolase domain GTHT12_RS00915 75ee604559d20bdf2d9ca7d77c2598a6 299 TIGRFAM TIGR01229 rocF_arginase: arginase 5 298 9.1E-111 T 06-07-2017 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 GTHT12_RS00915 75ee604559d20bdf2d9ca7d77c2598a6 299 PRINTS PR00116 Arginase signature 172 190 7.1E-43 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 GTHT12_RS00915 75ee604559d20bdf2d9ca7d77c2598a6 299 PRINTS PR00116 Arginase signature 221 250 7.1E-43 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 GTHT12_RS00915 75ee604559d20bdf2d9ca7d77c2598a6 299 PRINTS PR00116 Arginase signature 256 270 7.1E-43 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 GTHT12_RS00915 75ee604559d20bdf2d9ca7d77c2598a6 299 PRINTS PR00116 Arginase signature 95 110 7.1E-43 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 GTHT12_RS00915 75ee604559d20bdf2d9ca7d77c2598a6 299 PRINTS PR00116 Arginase signature 118 145 7.1E-43 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 GTHT12_RS00915 75ee604559d20bdf2d9ca7d77c2598a6 299 Pfam PF00491 Arginase family 3 294 2.4E-85 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 GTHT12_RS00915 75ee604559d20bdf2d9ca7d77c2598a6 299 ProSitePatterns PS01053 Arginase family signature. 224 245 - T 06-07-2017 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 GTHT12_RS00915 75ee604559d20bdf2d9ca7d77c2598a6 299 SUPERFAMILY SSF52768 3 295 3.96E-100 T 06-07-2017 GTHT12_RS14370 779cad4282a59489a59f1c85ade1aff2 329 PIRSF PIRSF026567 1 328 3.2E-144 T 06-07-2017 IPR016843 S-adenosyl-L-methionine dependent adenine methyltransferase, bacteria, predicted GTHT12_RS14370 779cad4282a59489a59f1c85ade1aff2 329 Pfam PF02384 N-6 DNA Methylase 96 308 9.7E-15 T 06-07-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 GTHT12_RS14370 779cad4282a59489a59f1c85ade1aff2 329 Gene3D G3DSA:3.40.50.150 96 297 8.6E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS14370 779cad4282a59489a59f1c85ade1aff2 329 SUPERFAMILY SSF53335 22 312 1.94E-46 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS13140 11e1e352dca1e2919a991f77d295421c 379 SUPERFAMILY SSF102114 3 376 4.05E-122 T 06-07-2017 GTHT12_RS13140 11e1e352dca1e2919a991f77d295421c 379 SMART SM00729 2 222 1.8E-64 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 GTHT12_RS13140 11e1e352dca1e2919a991f77d295421c 379 Pfam PF04055 Radical SAM superfamily 8 175 5.8E-23 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 GTHT12_RS13140 11e1e352dca1e2919a991f77d295421c 379 Gene3D G3DSA:3.80.30.20 3 238 3.2E-43 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe GTHT12_RS13140 11e1e352dca1e2919a991f77d295421c 379 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 4 364 3.7E-123 T 06-07-2017 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 GTHT12_RS13140 11e1e352dca1e2919a991f77d295421c 379 Pfam PF06969 HemN C-terminal domain 304 364 6.8E-15 T 06-07-2017 IPR010723 HemN, C-terminal GTHT12_RS12370 3ee4410ebe3a0d212c2d24643be03cbf 140 Gene3D G3DSA:3.10.180.10 1 133 8.1E-45 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GTHT12_RS12370 3ee4410ebe3a0d212c2d24643be03cbf 140 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 5 132 4.8E-47 T 06-07-2017 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|Reactome: R-HSA-71032 GTHT12_RS12370 3ee4410ebe3a0d212c2d24643be03cbf 140 SUPERFAMILY SSF54593 1 135 2.42E-35 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GTHT12_RS12370 3ee4410ebe3a0d212c2d24643be03cbf 140 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 117 7.4E-24 T 06-07-2017 GTHT12_RS05485 3dcdf7379df67766574f25d5fd0f4df7 255 Gene3D G3DSA:3.40.50.720 2 251 4.7E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS05485 3dcdf7379df67766574f25d5fd0f4df7 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 4.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05485 3dcdf7379df67766574f25d5fd0f4df7 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05485 3dcdf7379df67766574f25d5fd0f4df7 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05485 3dcdf7379df67766574f25d5fd0f4df7 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 4.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05485 3dcdf7379df67766574f25d5fd0f4df7 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 4.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05485 3dcdf7379df67766574f25d5fd0f4df7 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05485 3dcdf7379df67766574f25d5fd0f4df7 255 SUPERFAMILY SSF51735 2 250 2.83E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS05485 3dcdf7379df67766574f25d5fd0f4df7 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 247 6.0E-59 T 06-07-2017 GTHT12_RS05485 3dcdf7379df67766574f25d5fd0f4df7 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05485 3dcdf7379df67766574f25d5fd0f4df7 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05485 3dcdf7379df67766574f25d5fd0f4df7 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01840 c52146a65b5bc057a21f05e6b86217e0 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 118 1.3E-31 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS01840 c52146a65b5bc057a21f05e6b86217e0 384 Gene3D G3DSA:1.20.140.10 219 380 1.8E-43 T 06-07-2017 GTHT12_RS01840 c52146a65b5bc057a21f05e6b86217e0 384 SUPERFAMILY SSF47203 227 381 9.34E-40 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS01840 c52146a65b5bc057a21f05e6b86217e0 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 376 1.3E-31 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS01840 c52146a65b5bc057a21f05e6b86217e0 384 Gene3D G3DSA:2.40.110.10 122 218 3.9E-29 T 06-07-2017 GTHT12_RS01840 c52146a65b5bc057a21f05e6b86217e0 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 215 5.0E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 GTHT12_RS01840 c52146a65b5bc057a21f05e6b86217e0 384 Gene3D G3DSA:1.10.540.10 2 119 1.0E-36 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS01840 c52146a65b5bc057a21f05e6b86217e0 384 SUPERFAMILY SSF56645 2 239 4.06E-69 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 GTHT12_RS14425 1986a6afd4727adaa70bef78d31128b4 567 Hamap MF_00728 Septation ring formation regulator EzrA [ezrA]. 1 562 23.108 T 06-07-2017 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 GTHT12_RS14425 1986a6afd4727adaa70bef78d31128b4 567 Pfam PF06160 Septation ring formation regulator, EzrA 4 557 8.2E-184 T 06-07-2017 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 GTHT12_RS10615 ff0c3d59e7f82eb5f4249b043b0879b8 265 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 105 125 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 GTHT12_RS10615 ff0c3d59e7f82eb5f4249b043b0879b8 265 Gene3D G3DSA:1.10.12.10 208 264 1.9E-18 T 06-07-2017 IPR014748 Crontonase, C-terminal GTHT12_RS10615 ff0c3d59e7f82eb5f4249b043b0879b8 265 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 264 1.3E-58 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 GTHT12_RS10615 ff0c3d59e7f82eb5f4249b043b0879b8 265 Gene3D G3DSA:3.90.226.10 8 205 1.0E-60 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS10615 ff0c3d59e7f82eb5f4249b043b0879b8 265 SUPERFAMILY SSF52096 9 264 1.29E-72 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS16310 bf23e117183e564dbbe19375377a92ed 355 ProSitePatterns PS01348 MraY family signature 2. 144 155 - T 06-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 GTHT12_RS16310 bf23e117183e564dbbe19375377a92ed 355 Pfam PF00953 Glycosyl transferase family 4 71 224 1.1E-41 T 06-07-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 GTHT12_RS15530 c1855f75158dd53ad2db46d578578338 259 Pfam PF00005 ABC transporter 23 183 3.1E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS15530 c1855f75158dd53ad2db46d578578338 259 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 233 255 3.1E-13 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal GTHT12_RS15530 c1855f75158dd53ad2db46d578578338 259 Gene3D G3DSA:3.40.50.300 5 254 3.1E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS15530 c1855f75158dd53ad2db46d578578338 259 SUPERFAMILY SSF52540 6 256 2.97E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS15530 c1855f75158dd53ad2db46d578578338 259 SMART SM00382 32 232 3.4E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS01925 fb93ec63a593152cc3810510dfb2dcf9 426 Pfam PF02371 Transposase IS116/IS110/IS902 family 287 371 1.2E-21 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 GTHT12_RS01925 fb93ec63a593152cc3810510dfb2dcf9 426 Pfam PF01548 Transposase 19 179 9.4E-35 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 GTHT12_RS12675 fb93ec63a593152cc3810510dfb2dcf9 426 Pfam PF02371 Transposase IS116/IS110/IS902 family 287 371 1.2E-21 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 GTHT12_RS12675 fb93ec63a593152cc3810510dfb2dcf9 426 Pfam PF01548 Transposase 19 179 9.4E-35 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 GTHT12_RS01000 fb93ec63a593152cc3810510dfb2dcf9 426 Pfam PF02371 Transposase IS116/IS110/IS902 family 287 371 1.2E-21 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 GTHT12_RS01000 fb93ec63a593152cc3810510dfb2dcf9 426 Pfam PF01548 Transposase 19 179 9.4E-35 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 GTHT12_RS13345 fb93ec63a593152cc3810510dfb2dcf9 426 Pfam PF02371 Transposase IS116/IS110/IS902 family 287 371 1.2E-21 T 06-07-2017 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 GTHT12_RS13345 fb93ec63a593152cc3810510dfb2dcf9 426 Pfam PF01548 Transposase 19 179 9.4E-35 T 06-07-2017 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 GTHT12_RS07365 c56450fbc5b03facbc026857d132bc47 478 SUPERFAMILY SSF53335 79 284 8.68E-64 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS07365 c56450fbc5b03facbc026857d132bc47 478 SUPERFAMILY SSF53335 334 440 8.68E-64 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS07365 c56450fbc5b03facbc026857d132bc47 478 PIRSF PIRSF015855 7 477 1.7E-139 T 06-07-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 GTHT12_RS07365 c56450fbc5b03facbc026857d132bc47 478 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 112 118 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 GTHT12_RS07365 c56450fbc5b03facbc026857d132bc47 478 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 158 177 2.7E-15 T 06-07-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 GTHT12_RS07365 c56450fbc5b03facbc026857d132bc47 478 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 363 385 2.7E-15 T 06-07-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 GTHT12_RS07365 c56450fbc5b03facbc026857d132bc47 478 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 386 400 2.7E-15 T 06-07-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 GTHT12_RS07365 c56450fbc5b03facbc026857d132bc47 478 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 109 121 2.7E-15 T 06-07-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 GTHT12_RS07365 c56450fbc5b03facbc026857d132bc47 478 Gene3D G3DSA:3.40.50.150 85 261 2.2E-64 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS07365 c56450fbc5b03facbc026857d132bc47 478 Gene3D G3DSA:3.40.50.150 306 448 2.2E-64 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS07365 c56450fbc5b03facbc026857d132bc47 478 Pfam PF01555 DNA methylase 109 424 4.5E-40 T 06-07-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 GTHT12_RS17655 d72686bf41bd383c0c8fdeaf892564a3 283 PIRSF PIRSF000105 1 283 8.4E-98 T 06-07-2017 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 GTHT12_RS17655 d72686bf41bd383c0c8fdeaf892564a3 283 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 183 3.2E-71 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 GTHT12_RS17655 d72686bf41bd383c0c8fdeaf892564a3 283 Gene3D G3DSA:3.40.50.720 2 187 1.3E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS17655 d72686bf41bd383c0c8fdeaf892564a3 283 SUPERFAMILY SSF48179 185 283 1.19E-34 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GTHT12_RS17655 d72686bf41bd383c0c8fdeaf892564a3 283 Gene3D G3DSA:1.10.1040.10 188 283 2.6E-38 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 GTHT12_RS17655 d72686bf41bd383c0c8fdeaf892564a3 283 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 208 - T 06-07-2017 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 GTHT12_RS17655 d72686bf41bd383c0c8fdeaf892564a3 283 SUPERFAMILY SSF51735 1 185 9.18E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS17655 d72686bf41bd383c0c8fdeaf892564a3 283 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 6.1E-37 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 GTHT12_RS13805 7782beb738cec8b4418d17a0ae52f7c5 256 Pfam PF02602 Uroporphyrinogen-III synthase HemD 22 243 2.6E-61 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13805 7782beb738cec8b4418d17a0ae52f7c5 256 SUPERFAMILY SSF69618 8 252 1.18E-66 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13805 7782beb738cec8b4418d17a0ae52f7c5 256 Gene3D G3DSA:3.40.50.10090 129 252 1.3E-29 T 06-07-2017 GTHT12_RS13805 7782beb738cec8b4418d17a0ae52f7c5 256 Gene3D G3DSA:3.40.50.10090 4 128 6.1E-30 T 06-07-2017 GTHT12_RS16240 283c58120c2523fd99a287a0e7efc9ec 88 SUPERFAMILY SSF101498 1 84 6.67E-22 T 06-07-2017 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 GTHT12_RS16240 283c58120c2523fd99a287a0e7efc9ec 88 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 1 84 1.1E-20 T 06-07-2017 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 GTHT12_RS16240 283c58120c2523fd99a287a0e7efc9ec 88 Pfam PF04316 Anti-sigma-28 factor, FlgM 32 82 2.1E-16 T 06-07-2017 IPR031316 Anti-sigma-28 factor FlgM, C-terminal GTHT12_RS16955 1eb875a5c4df35d05d7e4cdb2071b6ee 428 PIRSF PIRSF000124 1 413 3.4E-78 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 GTHT12_RS16955 1eb875a5c4df35d05d7e4cdb2071b6ee 428 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2 179 1.5E-54 T 06-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 GTHT12_RS16955 1eb875a5c4df35d05d7e4cdb2071b6ee 428 Gene3D G3DSA:3.40.50.720 230 402 1.2E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS16955 1eb875a5c4df35d05d7e4cdb2071b6ee 428 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 2 396 6.1E-136 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 GTHT12_RS16955 1eb875a5c4df35d05d7e4cdb2071b6ee 428 PIRSF PIRSF500136 1 417 5.8E-156 T 06-07-2017 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 GTHT12_RS16955 1eb875a5c4df35d05d7e4cdb2071b6ee 428 SUPERFAMILY SSF48179 198 290 3.4E-26 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GTHT12_RS16955 1eb875a5c4df35d05d7e4cdb2071b6ee 428 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 309 400 3.0E-22 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 GTHT12_RS16955 1eb875a5c4df35d05d7e4cdb2071b6ee 428 SUPERFAMILY SSF52413 295 400 4.71E-27 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 GTHT12_RS16955 1eb875a5c4df35d05d7e4cdb2071b6ee 428 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 198 285 5.3E-25 T 06-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 GTHT12_RS16955 1eb875a5c4df35d05d7e4cdb2071b6ee 428 SUPERFAMILY SSF51735 2 192 1.45E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS16955 1eb875a5c4df35d05d7e4cdb2071b6ee 428 Gene3D G3DSA:3.40.50.720 2 219 5.0E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS16955 1eb875a5c4df35d05d7e4cdb2071b6ee 428 SMART SM00984 308 401 3.4E-29 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 GTHT12_RS01280 d090142e0ebc87f7481a84aab1b5eb10 364 Pfam PF07478 D-ala D-ala ligase C-terminus 143 345 3.0E-82 T 06-07-2017 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS01280 d090142e0ebc87f7481a84aab1b5eb10 364 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 4 348 1.7E-117 T 06-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS01280 d090142e0ebc87f7481a84aab1b5eb10 364 Gene3D G3DSA:3.40.50.20 1 125 2.4E-37 T 06-07-2017 IPR016185 Pre-ATP-grasp domain GTHT12_RS01280 d090142e0ebc87f7481a84aab1b5eb10 364 Gene3D G3DSA:3.30.470.20 223 362 6.9E-55 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 GTHT12_RS01280 d090142e0ebc87f7481a84aab1b5eb10 364 Gene3D G3DSA:3.30.1490.20 158 221 6.3E-27 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GTHT12_RS01280 d090142e0ebc87f7481a84aab1b5eb10 364 Pfam PF01820 D-ala D-ala ligase N-terminus 4 125 5.1E-33 T 06-07-2017 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS01280 d090142e0ebc87f7481a84aab1b5eb10 364 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 291 319 - T 06-07-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS01280 d090142e0ebc87f7481a84aab1b5eb10 364 PIRSF PIRSF039102 1 357 2.8E-124 T 06-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS01280 d090142e0ebc87f7481a84aab1b5eb10 364 SUPERFAMILY SSF52440 2 135 2.3E-36 T 06-07-2017 IPR016185 Pre-ATP-grasp domain GTHT12_RS01280 d090142e0ebc87f7481a84aab1b5eb10 364 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 3 349 42.684 T 06-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS01280 d090142e0ebc87f7481a84aab1b5eb10 364 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 103 114 - T 06-07-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS01280 d090142e0ebc87f7481a84aab1b5eb10 364 SUPERFAMILY SSF56059 136 354 1.77E-65 T 06-07-2017 GTHT12_RS13260 9a215113527d7399d4ed842f07e54d85 260 SUPERFAMILY SSF103088 127 248 4.32E-30 T 06-07-2017 IPR006665 OmpA-like domain GTHT12_RS13260 9a215113527d7399d4ed842f07e54d85 260 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 4 57 1.8E-21 T 06-07-2017 IPR025713 Motility protein B, N-terminal domain GTHT12_RS13260 9a215113527d7399d4ed842f07e54d85 260 Pfam PF00691 OmpA family 140 240 4.7E-16 T 06-07-2017 IPR006665 OmpA-like domain GTHT12_RS13260 9a215113527d7399d4ed842f07e54d85 260 Gene3D G3DSA:3.30.1330.60 122 246 2.8E-31 T 06-07-2017 IPR006665 OmpA-like domain GTHT12_RS11805 92d8c7f682afe6c93ac2c8c16e342fbc 222 SUPERFAMILY SSF141371 96 194 6.08E-8 T 06-07-2017 GTHT12_RS11805 92d8c7f682afe6c93ac2c8c16e342fbc 222 Pfam PF07238 PilZ domain 97 208 5.4E-16 T 06-07-2017 IPR009875 PilZ domain GO:0035438 GTHT12_RS11805 92d8c7f682afe6c93ac2c8c16e342fbc 222 Gene3D G3DSA:2.30.110.10 2 92 3.7E-5 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 GTHT12_RS11805 92d8c7f682afe6c93ac2c8c16e342fbc 222 Pfam PF12945 Flagellar protein YcgR 3 88 9.0E-17 T 06-07-2017 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal GTHT12_RS11805 92d8c7f682afe6c93ac2c8c16e342fbc 222 Gene3D G3DSA:2.40.10.220 98 219 2.2E-11 T 06-07-2017 GTHT12_RS06280 d364309eb2fbfc32cde5775559025f85 300 Pfam PF00549 CoA-ligase 151 265 3.3E-18 T 06-07-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 GTHT12_RS06280 d364309eb2fbfc32cde5775559025f85 300 Pfam PF02629 CoA binding domain 6 99 1.5E-33 T 06-07-2017 IPR003781 CoA-binding GO:0048037 GTHT12_RS06280 d364309eb2fbfc32cde5775559025f85 300 SMART SM00881 4 100 1.5E-37 T 06-07-2017 IPR003781 CoA-binding GO:0048037 GTHT12_RS06280 d364309eb2fbfc32cde5775559025f85 300 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 288 1.9E-150 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 GTHT12_RS06280 d364309eb2fbfc32cde5775559025f85 300 Gene3D G3DSA:3.40.50.261 120 286 2.9E-74 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 GTHT12_RS06280 d364309eb2fbfc32cde5775559025f85 300 SUPERFAMILY SSF51735 3 122 6.82E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS06280 d364309eb2fbfc32cde5775559025f85 300 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 06-07-2017 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site GTHT12_RS06280 d364309eb2fbfc32cde5775559025f85 300 SUPERFAMILY SSF52210 123 286 2.09E-54 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 GTHT12_RS06280 d364309eb2fbfc32cde5775559025f85 300 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 1.7E-41 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 GTHT12_RS06280 d364309eb2fbfc32cde5775559025f85 300 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 1.7E-41 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 GTHT12_RS06280 d364309eb2fbfc32cde5775559025f85 300 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 1.7E-41 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 GTHT12_RS06280 d364309eb2fbfc32cde5775559025f85 300 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 1.7E-41 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 GTHT12_RS06280 d364309eb2fbfc32cde5775559025f85 300 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 GTHT12_RS06280 d364309eb2fbfc32cde5775559025f85 300 Gene3D G3DSA:3.40.50.720 2 119 2.4E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS06280 d364309eb2fbfc32cde5775559025f85 300 PIRSF PIRSF001553 1 291 2.0E-136 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 GTHT12_RS13730 6d0a254ff907de211de60eb6379ca24e 554 Gene3D G3DSA:3.30.450.90 158 278 3.0E-49 T 06-07-2017 GTHT12_RS13730 6d0a254ff907de211de60eb6379ca24e 554 SUPERFAMILY SSF52540 165 550 4.19E-100 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13730 6d0a254ff907de211de60eb6379ca24e 554 Gene3D G3DSA:3.40.50.300 283 551 1.1E-101 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13730 6d0a254ff907de211de60eb6379ca24e 554 SMART SM00382 306 429 2.6E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS13730 6d0a254ff907de211de60eb6379ca24e 554 Pfam PF00437 Type II/IV secretion system protein 184 445 8.4E-76 T 06-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 GTHT12_RS13730 6d0a254ff907de211de60eb6379ca24e 554 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 42 146 7.0E-28 T 06-07-2017 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 GTHT12_RS13730 6d0a254ff907de211de60eb6379ca24e 554 SUPERFAMILY SSF160246 5 144 1.31E-45 T 06-07-2017 GTHT12_RS18140 1da37385edc2252f6bafcf5804528df2 149 Gene3D G3DSA:3.40.5.10 1 51 1.3E-25 T 06-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS18140 1da37385edc2252f6bafcf5804528df2 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 146 4.7E-33 T 06-07-2017 IPR020069 Ribosomal protein L9, C-terminal GTHT12_RS18140 1da37385edc2252f6bafcf5804528df2 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 27.432 T 06-07-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS18140 1da37385edc2252f6bafcf5804528df2 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 4.9E-24 T 06-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS18140 1da37385edc2252f6bafcf5804528df2 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 2.9E-53 T 06-07-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS18140 1da37385edc2252f6bafcf5804528df2 149 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 06-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS18140 1da37385edc2252f6bafcf5804528df2 149 SUPERFAMILY SSF55653 57 148 2.49E-31 T 06-07-2017 IPR020069 Ribosomal protein L9, C-terminal GTHT12_RS18140 1da37385edc2252f6bafcf5804528df2 149 Gene3D G3DSA:3.10.430.100 60 148 1.1E-35 T 06-07-2017 IPR020069 Ribosomal protein L9, C-terminal GTHT12_RS18140 1da37385edc2252f6bafcf5804528df2 149 SUPERFAMILY SSF55658 1 56 1.45E-18 T 06-07-2017 IPR009027 Ribosomal protein L9/RNase H1, N-terminal GTHT12_RS07935 7f8f8c094504aa25034d5a4625d7e42c 378 Gene3D G3DSA:3.40.50.150 251 373 2.2E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS07935 7f8f8c094504aa25034d5a4625d7e42c 378 Gene3D G3DSA:3.40.50.150 145 214 2.2E-34 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS07935 7f8f8c094504aa25034d5a4625d7e42c 378 SMART SM00981 57 154 6.1E-10 T 06-07-2017 IPR004114 THUMP domain GO:0003723 GTHT12_RS07935 7f8f8c094504aa25034d5a4625d7e42c 378 Pfam PF01170 Putative RNA methylase family UPF0020 162 367 2.2E-62 T 06-07-2017 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS07935 7f8f8c094504aa25034d5a4625d7e42c 378 SUPERFAMILY SSF53335 143 217 3.46E-44 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS07935 7f8f8c094504aa25034d5a4625d7e42c 378 SUPERFAMILY SSF53335 254 371 3.46E-44 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS07935 7f8f8c094504aa25034d5a4625d7e42c 378 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 195 206 - T 06-07-2017 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS07935 7f8f8c094504aa25034d5a4625d7e42c 378 Pfam PF02926 THUMP domain 15 154 5.6E-13 T 06-07-2017 IPR004114 THUMP domain GO:0003723 GTHT12_RS07935 7f8f8c094504aa25034d5a4625d7e42c 378 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 299 305 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 GTHT12_RS13590 7b7a11bc35c4189b259ee43efa3471c2 520 SUPERFAMILY SSF46977 418 513 3.01E-18 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GTHT12_RS13590 7b7a11bc35c4189b259ee43efa3471c2 520 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 6 495 7.0E-163 T 06-07-2017 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 GTHT12_RS13590 7b7a11bc35c4189b259ee43efa3471c2 520 SUPERFAMILY SSF56425 220 330 2.09E-32 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 GTHT12_RS13590 7b7a11bc35c4189b259ee43efa3471c2 520 SUPERFAMILY SSF51905 6 246 1.02E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS13590 7b7a11bc35c4189b259ee43efa3471c2 520 SUPERFAMILY SSF51905 334 386 1.02E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS13590 7b7a11bc35c4189b259ee43efa3471c2 520 Gene3D G3DSA:3.90.700.10 226 326 1.2E-29 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 GTHT12_RS13590 7b7a11bc35c4189b259ee43efa3471c2 520 Pfam PF00890 FAD binding domain 6 370 1.3E-82 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 GTHT12_RS13590 7b7a11bc35c4189b259ee43efa3471c2 520 Gene3D G3DSA:3.50.50.60 327 385 3.9E-90 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS13590 7b7a11bc35c4189b259ee43efa3471c2 520 Gene3D G3DSA:3.50.50.60 6 225 3.9E-90 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS13590 7b7a11bc35c4189b259ee43efa3471c2 520 Pfam PF02910 Fumarate reductase flavoprotein C-term 462 507 1.4E-7 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GTHT12_RS13590 7b7a11bc35c4189b259ee43efa3471c2 520 Gene3D G3DSA:1.20.58.100 419 511 3.9E-14 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GTHT12_RS13590 7b7a11bc35c4189b259ee43efa3471c2 520 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 8.9E-11 T 06-07-2017 GTHT12_RS13590 7b7a11bc35c4189b259ee43efa3471c2 520 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 246 8.9E-11 T 06-07-2017 GTHT12_RS13590 7b7a11bc35c4189b259ee43efa3471c2 520 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 312 328 8.9E-11 T 06-07-2017 GTHT12_RS13590 7b7a11bc35c4189b259ee43efa3471c2 520 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 333 355 8.9E-11 T 06-07-2017 GTHT12_RS00320 fdbee0efec028ee79d85b727e9b02784 93 PIRSF PIRSF038881 1 89 4.1E-37 T 06-07-2017 IPR025490 RNA-binding protein, HP1423 type GTHT12_RS00320 fdbee0efec028ee79d85b727e9b02784 93 Pfam PF01479 S4 domain 1 47 3.2E-12 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS00320 fdbee0efec028ee79d85b727e9b02784 93 SMART SM00363 1 64 2.3E-11 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS00320 fdbee0efec028ee79d85b727e9b02784 93 SUPERFAMILY SSF55174 1 81 4.84E-21 T 06-07-2017 GTHT12_RS00320 fdbee0efec028ee79d85b727e9b02784 93 Gene3D G3DSA:3.10.290.10 1 85 4.3E-25 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS07580 482c7a595f98b2978b096bed46a25506 99 Gene3D G3DSA:3.30.70.1480 1 99 2.6E-49 T 06-07-2017 IPR028990 GK1464-like GTHT12_RS07580 482c7a595f98b2978b096bed46a25506 99 SUPERFAMILY SSF143579 1 99 3.66E-47 T 06-07-2017 IPR028990 GK1464-like GTHT12_RS13215 67d1e0d66afce87b92d1a2a0ba9e62c5 216 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 2 188 33.056 T 06-07-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 GTHT12_RS13215 67d1e0d66afce87b92d1a2a0ba9e62c5 216 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 66 7.5E-12 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 GTHT12_RS13215 67d1e0d66afce87b92d1a2a0ba9e62c5 216 SUPERFAMILY SSF52374 1 190 2.03E-57 T 06-07-2017 GTHT12_RS13215 67d1e0d66afce87b92d1a2a0ba9e62c5 216 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 6 187 6.9E-60 T 06-07-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 GTHT12_RS13215 67d1e0d66afce87b92d1a2a0ba9e62c5 216 Gene3D G3DSA:3.40.50.620 3 190 4.2E-68 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS13215 67d1e0d66afce87b92d1a2a0ba9e62c5 216 Pfam PF01467 Cytidylyltransferase-like 6 162 9.3E-34 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 GTHT12_RS03335 2b81d325591e00111a7f1c18a6955e07 525 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 423 524 2.0E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS03335 2b81d325591e00111a7f1c18a6955e07 525 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 318 374 8.9E-15 T 06-07-2017 GTHT12_RS03335 2b81d325591e00111a7f1c18a6955e07 525 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 505 1.7E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS03335 2b81d325591e00111a7f1c18a6955e07 525 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 524 1.7E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS03335 2b81d325591e00111a7f1c18a6955e07 525 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 471 1.7E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS03335 2b81d325591e00111a7f1c18a6955e07 525 PRINTS PR00344 Bacterial sensor protein C-terminal signature 475 485 1.7E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS03335 2b81d325591e00111a7f1c18a6955e07 525 Pfam PF13188 PAS domain 217 262 1.6E-5 T 06-07-2017 IPR000014 PAS domain GTHT12_RS03335 2b81d325591e00111a7f1c18a6955e07 525 Pfam PF17203 Single cache domain 3 38 157 1.0E-16 T 06-07-2017 IPR033463 Single cache domain 3 GTHT12_RS03335 2b81d325591e00111a7f1c18a6955e07 525 Gene3D G3DSA:3.30.565.10 414 523 6.5E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS03335 2b81d325591e00111a7f1c18a6955e07 525 SUPERFAMILY SSF55874 411 523 8.77E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS03335 2b81d325591e00111a7f1c18a6955e07 525 SUPERFAMILY SSF103190 36 167 6.67E-31 T 06-07-2017 IPR029151 Periplasmic sensor domain-like GTHT12_RS03335 2b81d325591e00111a7f1c18a6955e07 525 SMART SM00091 212 277 1.9E-5 T 06-07-2017 IPR000014 PAS domain GTHT12_RS03335 2b81d325591e00111a7f1c18a6955e07 525 SMART SM00387 416 525 1.4E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS03335 2b81d325591e00111a7f1c18a6955e07 525 Gene3D G3DSA:3.30.450.20 218 314 1.7E-11 T 06-07-2017 GTHT12_RS03335 2b81d325591e00111a7f1c18a6955e07 525 Gene3D G3DSA:1.10.287.130 315 374 1.6E-23 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS03335 2b81d325591e00111a7f1c18a6955e07 525 SUPERFAMILY SSF55890 319 388 7.32E-16 T 06-07-2017 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 GTHT12_RS03335 2b81d325591e00111a7f1c18a6955e07 525 SUPERFAMILY SSF55785 223 320 2.66E-9 T 06-07-2017 IPR000014 PAS domain GTHT12_RS03335 2b81d325591e00111a7f1c18a6955e07 525 Gene3D G3DSA:3.30.450.20 34 167 6.0E-37 T 06-07-2017 GTHT12_RS09750 d23aab74df3f78f46299175adc400902 470 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 369 377 - T 06-07-2017 IPR018120 Glycoside hydrolase family 1, active site GTHT12_RS09750 d23aab74df3f78f46299175adc400902 470 Pfam PF00232 Glycosyl hydrolase family 1 12 470 7.2E-147 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 GTHT12_RS09750 d23aab74df3f78f46299175adc400902 470 SUPERFAMILY SSF51445 11 470 6.65E-177 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS09750 d23aab74df3f78f46299175adc400902 470 PRINTS PR00131 Glycosyl hydrolase family 1 signature 438 450 1.1E-17 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 GTHT12_RS09750 d23aab74df3f78f46299175adc400902 470 PRINTS PR00131 Glycosyl hydrolase family 1 signature 369 377 1.1E-17 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 GTHT12_RS09750 d23aab74df3f78f46299175adc400902 470 PRINTS PR00131 Glycosyl hydrolase family 1 signature 393 404 1.1E-17 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 GTHT12_RS09750 d23aab74df3f78f46299175adc400902 470 PRINTS PR00131 Glycosyl hydrolase family 1 signature 414 431 1.1E-17 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 GTHT12_RS09750 d23aab74df3f78f46299175adc400902 470 PRINTS PR00131 Glycosyl hydrolase family 1 signature 297 311 1.1E-17 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 GTHT12_RS09750 d23aab74df3f78f46299175adc400902 470 Gene3D G3DSA:3.20.20.80 11 470 1.8E-160 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS17490 605d3f9d3057d3aaa57046466ead7c37 178 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 6 176 3.6E-51 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 GTHT12_RS17490 605d3f9d3057d3aaa57046466ead7c37 178 Pfam PF00213 ATP synthase delta (OSCP) subunit 6 176 2.4E-53 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 GTHT12_RS17490 605d3f9d3057d3aaa57046466ead7c37 178 Hamap MF_01416 ATP synthase subunit delta [atpD]. 2 178 21.642 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 GTHT12_RS17490 605d3f9d3057d3aaa57046466ead7c37 178 PRINTS PR00125 ATP synthase delta subunit signature 85 99 3.8E-29 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 GTHT12_RS17490 605d3f9d3057d3aaa57046466ead7c37 178 PRINTS PR00125 ATP synthase delta subunit signature 151 169 3.8E-29 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 GTHT12_RS17490 605d3f9d3057d3aaa57046466ead7c37 178 PRINTS PR00125 ATP synthase delta subunit signature 74 85 3.8E-29 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 GTHT12_RS17490 605d3f9d3057d3aaa57046466ead7c37 178 PRINTS PR00125 ATP synthase delta subunit signature 6 25 3.8E-29 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 GTHT12_RS17490 605d3f9d3057d3aaa57046466ead7c37 178 PRINTS PR00125 ATP synthase delta subunit signature 136 151 3.8E-29 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 GTHT12_RS17490 605d3f9d3057d3aaa57046466ead7c37 178 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 138 157 - T 06-07-2017 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210 GTHT12_RS17490 605d3f9d3057d3aaa57046466ead7c37 178 Gene3D G3DSA:1.10.520.20 5 105 8.6E-24 T 06-07-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 GTHT12_RS17490 605d3f9d3057d3aaa57046466ead7c37 178 SUPERFAMILY SSF47928 4 106 1.44E-25 T 06-07-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 GTHT12_RS05620 697544730ee16d00e8291b6ad3fa863a 102 Pfam PF05256 Uncharacterised protein family (UPF0223) 3 85 3.9E-36 T 06-07-2017 IPR007920 Protein of unknown function UPF0223 GTHT12_RS05620 697544730ee16d00e8291b6ad3fa863a 102 PIRSF PIRSF037260 1 90 2.5E-35 T 06-07-2017 IPR007920 Protein of unknown function UPF0223 GTHT12_RS05620 697544730ee16d00e8291b6ad3fa863a 102 Gene3D G3DSA:1.10.220.80 12 88 2.9E-33 T 06-07-2017 IPR023324 BH2638-like domain GTHT12_RS05620 697544730ee16d00e8291b6ad3fa863a 102 SUPERFAMILY SSF158504 4 84 9.55E-33 T 06-07-2017 IPR023324 BH2638-like domain GTHT12_RS05620 697544730ee16d00e8291b6ad3fa863a 102 Hamap MF_01041 UPF0223 protein . 1 89 24.436 T 06-07-2017 IPR007920 Protein of unknown function UPF0223 GTHT12_RS05620 697544730ee16d00e8291b6ad3fa863a 102 ProDom PD062738 UPF0223 FAMILY UNCHARACTERISED CYTOSOLIC SUPERFAMILY YKTA LMO1058/LIN1050 INOSITOL MW0980 M6_SPY0948 3 85 1.0E-22 T 06-07-2017 IPR007920 Protein of unknown function UPF0223 GTHT12_RS14520 88ab14efeb81fa884bbabe1fe986b5d5 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 84 99 1.1E-21 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS14520 88ab14efeb81fa884bbabe1fe986b5d5 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 67 1.1E-21 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS14520 88ab14efeb81fa884bbabe1fe986b5d5 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 1.1E-21 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS14520 88ab14efeb81fa884bbabe1fe986b5d5 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 1.1E-21 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS14520 88ab14efeb81fa884bbabe1fe986b5d5 122 Pfam PF01022 Bacterial regulatory protein, arsR family 41 88 9.2E-17 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS14520 88ab14efeb81fa884bbabe1fe986b5d5 122 SMART SM00418 34 113 2.9E-31 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS14520 88ab14efeb81fa884bbabe1fe986b5d5 122 SUPERFAMILY SSF46785 20 109 1.41E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS14520 88ab14efeb81fa884bbabe1fe986b5d5 122 Gene3D G3DSA:1.10.10.10 3 114 8.9E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS14520 88ab14efeb81fa884bbabe1fe986b5d5 122 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 58 76 - T 06-07-2017 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 GTHT12_RS07700 9bcfc45efec26214384b43640ed44051 511 Pfam PF03853 YjeF-related protein N-terminus 26 191 6.9E-48 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 GTHT12_RS07700 9bcfc45efec26214384b43640ed44051 511 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 5 213 1.5E-49 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 GTHT12_RS07700 9bcfc45efec26214384b43640ed44051 511 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 6 212 25.32 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 GTHT12_RS07700 9bcfc45efec26214384b43640ed44051 511 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 230 503 5.7E-68 T 06-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 GTHT12_RS07700 9bcfc45efec26214384b43640ed44051 511 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 441 451 - T 06-07-2017 IPR017953 Carbohydrate kinase, predicted, conserved site GTHT12_RS07700 9bcfc45efec26214384b43640ed44051 511 Gene3D G3DSA:3.40.1190.20 236 505 1.1E-82 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS07700 9bcfc45efec26214384b43640ed44051 511 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 227 507 22.528 T 06-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 GTHT12_RS07700 9bcfc45efec26214384b43640ed44051 511 PIRSF PIRSF017184 2 508 1.0E-142 T 06-07-2017 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 GTHT12_RS07700 9bcfc45efec26214384b43640ed44051 511 Pfam PF01256 Carbohydrate kinase 250 498 5.9E-57 T 06-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 GTHT12_RS07700 9bcfc45efec26214384b43640ed44051 511 SUPERFAMILY SSF64153 3 248 7.06E-64 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 GTHT12_RS07700 9bcfc45efec26214384b43640ed44051 511 Gene3D G3DSA:3.40.50.10260 1 235 2.8E-72 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 GTHT12_RS07700 9bcfc45efec26214384b43640ed44051 511 SUPERFAMILY SSF53613 224 504 5.58E-72 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS07645 c87a8aa6c49bce9b82935e1455be1d80 509 Gene3D G3DSA:3.30.300.30 403 502 1.8E-31 T 06-07-2017 GTHT12_RS07645 c87a8aa6c49bce9b82935e1455be1d80 509 Gene3D G3DSA:3.40.50.980 167 326 2.5E-45 T 06-07-2017 GTHT12_RS07645 c87a8aa6c49bce9b82935e1455be1d80 509 Pfam PF13193 AMP-binding enzyme C-terminal domain 417 492 3.5E-18 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain GTHT12_RS07645 c87a8aa6c49bce9b82935e1455be1d80 509 ProSitePatterns PS00455 Putative AMP-binding domain signature. 160 171 - T 06-07-2017 IPR020845 AMP-binding, conserved site GTHT12_RS07645 c87a8aa6c49bce9b82935e1455be1d80 509 SUPERFAMILY SSF56801 3 504 5.36E-164 T 06-07-2017 GTHT12_RS07645 c87a8aa6c49bce9b82935e1455be1d80 509 Pfam PF00501 AMP-binding enzyme 8 408 2.1E-114 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GTHT12_RS07645 c87a8aa6c49bce9b82935e1455be1d80 509 Gene3D G3DSA:3.40.50.980 2 166 1.6E-44 T 06-07-2017 GTHT12_RS07645 c87a8aa6c49bce9b82935e1455be1d80 509 Gene3D G3DSA:2.30.38.10 327 399 9.3E-27 T 06-07-2017 GTHT12_RS11560 9a37f7fb63264e10182452c927e10203 265 PIRSF PIRSF000161 1 265 4.4E-73 T 06-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS11560 9a37f7fb63264e10182452c927e10203 265 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 2 265 3.6E-87 T 06-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS11560 9a37f7fb63264e10182452c927e10203 265 SUPERFAMILY SSF55347 128 236 2.4E-40 T 06-07-2017 GTHT12_RS11560 9a37f7fb63264e10182452c927e10203 265 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 149 166 - T 06-07-2017 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS11560 9a37f7fb63264e10182452c927e10203 265 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 127 2.9E-32 T 06-07-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS11560 9a37f7fb63264e10182452c927e10203 265 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 3 265 31.187 T 06-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS11560 9a37f7fb63264e10182452c927e10203 265 Gene3D G3DSA:3.30.360.10 144 233 1.5E-37 T 06-07-2017 GTHT12_RS11560 9a37f7fb63264e10182452c927e10203 265 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 130 264 9.9E-35 T 06-07-2017 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS11560 9a37f7fb63264e10182452c927e10203 265 Gene3D G3DSA:3.40.50.720 2 143 1.3E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS11560 9a37f7fb63264e10182452c927e10203 265 SUPERFAMILY SSF51735 2 154 8.41E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS12790 28fe21232cd336761a3d07c70ef80f5a 232 Gene3D G3DSA:3.30.1380.20 112 229 1.4E-5 T 06-07-2017 GTHT12_RS12790 28fe21232cd336761a3d07c70ef80f5a 232 SMART SM00418 6 92 0.0021 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS12790 28fe21232cd336761a3d07c70ef80f5a 232 SUPERFAMILY SSF46785 1 206 1.06E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12790 28fe21232cd336761a3d07c70ef80f5a 232 Pfam PF12840 Helix-turn-helix domain 7 62 7.1E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12790 28fe21232cd336761a3d07c70ef80f5a 232 Gene3D G3DSA:1.10.10.10 2 82 1.7E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12670 681ac4043bb2c37d17eb689294e4627c 470 Gene3D G3DSA:3.10.350.10 50 97 1.6E-16 T 06-07-2017 IPR018392 LysM domain GTHT12_RS12670 681ac4043bb2c37d17eb689294e4627c 470 Gene3D G3DSA:3.10.350.10 98 144 1.9E-16 T 06-07-2017 IPR018392 LysM domain GTHT12_RS12670 681ac4043bb2c37d17eb689294e4627c 470 Gene3D G3DSA:3.10.350.10 2 48 2.7E-13 T 06-07-2017 IPR018392 LysM domain GTHT12_RS12670 681ac4043bb2c37d17eb689294e4627c 470 SMART SM00636 170 452 2.5E-11 T 06-07-2017 IPR011583 Chitinase II GO:0004568|GO:0006032 GTHT12_RS12670 681ac4043bb2c37d17eb689294e4627c 470 SUPERFAMILY SSF54106 2 48 4.45E-10 T 06-07-2017 IPR018392 LysM domain GTHT12_RS12670 681ac4043bb2c37d17eb689294e4627c 470 SMART SM00257 3 47 3.3E-11 T 06-07-2017 IPR018392 LysM domain GTHT12_RS12670 681ac4043bb2c37d17eb689294e4627c 470 SMART SM00257 99 143 9.8E-18 T 06-07-2017 IPR018392 LysM domain GTHT12_RS12670 681ac4043bb2c37d17eb689294e4627c 470 SMART SM00257 52 96 7.4E-16 T 06-07-2017 IPR018392 LysM domain GTHT12_RS12670 681ac4043bb2c37d17eb689294e4627c 470 SUPERFAMILY SSF54106 98 143 8.76E-12 T 06-07-2017 IPR018392 LysM domain GTHT12_RS12670 681ac4043bb2c37d17eb689294e4627c 470 Pfam PF00704 Glycosyl hydrolases family 18 229 450 4.7E-22 T 06-07-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 GTHT12_RS12670 681ac4043bb2c37d17eb689294e4627c 470 SUPERFAMILY SSF51445 423 462 1.33E-39 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS12670 681ac4043bb2c37d17eb689294e4627c 470 SUPERFAMILY SSF51445 172 364 1.33E-39 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS12670 681ac4043bb2c37d17eb689294e4627c 470 Pfam PF01476 LysM domain 53 96 7.7E-13 T 06-07-2017 IPR018392 LysM domain GTHT12_RS12670 681ac4043bb2c37d17eb689294e4627c 470 Pfam PF01476 LysM domain 100 143 1.5E-12 T 06-07-2017 IPR018392 LysM domain GTHT12_RS12670 681ac4043bb2c37d17eb689294e4627c 470 Pfam PF01476 LysM domain 4 47 1.7E-10 T 06-07-2017 IPR018392 LysM domain GTHT12_RS12670 681ac4043bb2c37d17eb689294e4627c 470 SUPERFAMILY SSF54106 51 96 7.06E-12 T 06-07-2017 IPR018392 LysM domain GTHT12_RS12670 681ac4043bb2c37d17eb689294e4627c 470 Gene3D G3DSA:3.20.20.80 223 450 3.6E-26 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS17340 f29e7376092d94da453faa0e3db65680 276 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 199 270 1.1E-17 T 06-07-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain GTHT12_RS17340 f29e7376092d94da453faa0e3db65680 276 Pfam PF00460 Flagella basal body rod protein 5 35 1.6E-10 T 06-07-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 GTHT12_RS17340 f29e7376092d94da453faa0e3db65680 276 SUPERFAMILY SSF117143 118 233 4.84E-20 T 06-07-2017 GTHT12_RS17340 f29e7376092d94da453faa0e3db65680 276 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 155 9.1E-29 T 06-07-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G GTHT12_RS02985 dea177f1036316a3e06e5307b4cc46fe 177 PIRSF PIRSF028345 2 177 7.7E-80 T 06-07-2017 IPR016882 Uncharacterised protein family UPF0374 GTHT12_RS02985 dea177f1036316a3e06e5307b4cc46fe 177 SUPERFAMILY SSF159234 4 170 1.44E-29 T 06-07-2017 GTHT12_RS02985 dea177f1036316a3e06e5307b4cc46fe 177 Gene3D G3DSA:2.40.380.10 4 169 2.1E-51 T 06-07-2017 IPR007295 Domain of unknown function DUF402 GTHT12_RS02985 dea177f1036316a3e06e5307b4cc46fe 177 Pfam PF04167 Protein of unknown function (DUF402) 61 125 6.8E-18 T 06-07-2017 IPR007295 Domain of unknown function DUF402 GTHT12_RS02985 dea177f1036316a3e06e5307b4cc46fe 177 Hamap MF_01568 UPF0374 protein . 2 176 50.933 T 06-07-2017 IPR016882 Uncharacterised protein family UPF0374 GTHT12_RS03980 ad9f58a0ee4596cc86deb9a9e7c66099 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 247 7.5E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS03980 ad9f58a0ee4596cc86deb9a9e7c66099 267 SUPERFAMILY SSF161098 5 252 4.71E-47 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS03980 ad9f58a0ee4596cc86deb9a9e7c66099 267 Gene3D G3DSA:1.10.3720.10 6 259 1.3E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS18135 acce1d566e98ee978b2696b485ef7cdb 454 Pfam PF00772 DnaB-like helicase N terminal domain 10 111 1.2E-35 T 06-07-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 GTHT12_RS18135 acce1d566e98ee978b2696b485ef7cdb 454 SUPERFAMILY SSF48024 8 119 1.57E-37 T 06-07-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 GTHT12_RS18135 acce1d566e98ee978b2696b485ef7cdb 454 Gene3D G3DSA:3.40.50.300 170 442 2.0E-114 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18135 acce1d566e98ee978b2696b485ef7cdb 454 Gene3D G3DSA:1.10.860.10 10 112 1.7E-39 T 06-07-2017 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal GTHT12_RS18135 acce1d566e98ee978b2696b485ef7cdb 454 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 10 442 2.8E-192 T 06-07-2017 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 GTHT12_RS18135 acce1d566e98ee978b2696b485ef7cdb 454 Pfam PF03796 DnaB-like helicase C terminal domain 185 440 1.0E-123 T 06-07-2017 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 GTHT12_RS18135 acce1d566e98ee978b2696b485ef7cdb 454 SUPERFAMILY SSF52540 183 433 1.38E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11600 2ba5285d86e50d1b63060b439ed5959a 151 Pfam PF10673 Protein of unknown function (DUF2487) 10 148 7.8E-49 T 06-07-2017 IPR019615 Protein of unknown function DUF2487 GTHT12_RS01730 45dcaefaa08132fc58dea331ef30fe48 434 SUPERFAMILY SSF53383 8 426 6.12E-134 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS01730 45dcaefaa08132fc58dea331ef30fe48 434 PIRSF PIRSF001434 1 429 3.5E-137 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 GTHT12_RS01730 45dcaefaa08132fc58dea331ef30fe48 434 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 9 425 4.0E-214 T 06-07-2017 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 KEGG: 00270+2.5.1.49|MetaCyc: PWY-5344|MetaCyc: PWY-7174 GTHT12_RS01730 45dcaefaa08132fc58dea331ef30fe48 434 Gene3D G3DSA:3.40.640.10 8 290 3.0E-128 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS01730 45dcaefaa08132fc58dea331ef30fe48 434 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 202 216 - T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 GTHT12_RS01730 45dcaefaa08132fc58dea331ef30fe48 434 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 425 8.7E-156 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 GTHT12_RS01730 45dcaefaa08132fc58dea331ef30fe48 434 Gene3D G3DSA:3.90.1150.10 292 427 1.3E-52 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS11920 f8baa76177efaf822620dcbba09bcaba 181 Gene3D G3DSA:1.10.1740.10 5 99 8.3E-27 T 06-07-2017 GTHT12_RS11920 f8baa76177efaf822620dcbba09bcaba 181 Pfam PF04542 Sigma-70 region 2 8 74 2.9E-17 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS11920 f8baa76177efaf822620dcbba09bcaba 181 Gene3D G3DSA:1.10.10.10 103 167 4.0E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS11920 f8baa76177efaf822620dcbba09bcaba 181 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 30 61 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS11920 f8baa76177efaf822620dcbba09bcaba 181 SUPERFAMILY SSF88946 4 82 7.46E-24 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS11920 f8baa76177efaf822620dcbba09bcaba 181 SUPERFAMILY SSF88659 79 167 3.36E-16 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS11920 f8baa76177efaf822620dcbba09bcaba 181 Pfam PF08281 Sigma-70, region 4 108 160 3.0E-10 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS11920 f8baa76177efaf822620dcbba09bcaba 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 164 2.1E-33 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS18670 fa352efdd820e1e3ef0e5b6384cd948c 189 Gene3D G3DSA:1.10.443.10 10 183 2.1E-40 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS18670 fa352efdd820e1e3ef0e5b6384cd948c 189 SUPERFAMILY SSF56349 6 185 7.36E-45 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 GTHT12_RS18670 fa352efdd820e1e3ef0e5b6384cd948c 189 Pfam PF00589 Phage integrase family 10 174 2.0E-28 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS10155 e09ba3cfee62be02a47d934de8d257d5 400 Gene3D G3DSA:3.20.20.140 64 380 2.2E-38 T 06-07-2017 GTHT12_RS10155 e09ba3cfee62be02a47d934de8d257d5 400 Gene3D G3DSA:2.30.40.10 3 63 9.2E-17 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS10155 e09ba3cfee62be02a47d934de8d257d5 400 Pfam PF01979 Amidohydrolase family 54 380 1.8E-25 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 GTHT12_RS10155 e09ba3cfee62be02a47d934de8d257d5 400 SUPERFAMILY SSF51338 3 58 5.37E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS10155 e09ba3cfee62be02a47d934de8d257d5 400 SUPERFAMILY SSF51338 346 385 5.37E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS10155 e09ba3cfee62be02a47d934de8d257d5 400 SUPERFAMILY SSF51556 57 347 3.18E-55 T 06-07-2017 IPR032466 Metal-dependent hydrolase GTHT12_RS07415 9ae2f827d30c8d0cc00d56912a9d2d81 1519 Gene3D G3DSA:2.160.20.60 1220 1491 1.7E-106 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 GTHT12_RS07415 9ae2f827d30c8d0cc00d56912a9d2d81 1519 Pfam PF01645 Conserved region in glutamate synthase 798 1166 3.1E-162 T 06-07-2017 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 GTHT12_RS07415 9ae2f827d30c8d0cc00d56912a9d2d81 1519 Pfam PF01493 GXGXG motif 1244 1430 1.9E-83 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 GTHT12_RS07415 9ae2f827d30c8d0cc00d56912a9d2d81 1519 Pfam PF04898 Glutamate synthase central domain 462 738 1.2E-116 T 06-07-2017 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 GTHT12_RS07415 9ae2f827d30c8d0cc00d56912a9d2d81 1519 Gene3D G3DSA:3.60.20.10 22 447 6.1E-188 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal GTHT12_RS07415 9ae2f827d30c8d0cc00d56912a9d2d81 1519 SUPERFAMILY SSF56235 22 439 3.58E-156 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal GTHT12_RS07415 9ae2f827d30c8d0cc00d56912a9d2d81 1519 Pfam PF00310 Glutamine amidotransferases class-II 22 436 4.6E-187 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain GTHT12_RS07415 9ae2f827d30c8d0cc00d56912a9d2d81 1519 SUPERFAMILY SSF69336 1213 1479 9.81E-97 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 GTHT12_RS07415 9ae2f827d30c8d0cc00d56912a9d2d81 1519 SUPERFAMILY SSF51395 444 1203 3.91E-268 T 06-07-2017 GTHT12_RS07415 9ae2f827d30c8d0cc00d56912a9d2d81 1519 Gene3D G3DSA:3.20.20.70 453 783 4.3E-106 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS07415 9ae2f827d30c8d0cc00d56912a9d2d81 1519 Gene3D G3DSA:3.20.20.70 801 1202 1.1E-184 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS09795 c66c4e014cc2cdb7dd861e8633590e8b 499 Gene3D G3DSA:3.30.420.40 2 248 1.5E-73 T 06-07-2017 GTHT12_RS09795 c66c4e014cc2cdb7dd861e8633590e8b 499 PIRSF PIRSF000538 1 496 9.8E-163 T 06-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 GTHT12_RS09795 c66c4e014cc2cdb7dd861e8633590e8b 499 PRINTS PR00475 Hexokinase family signature 170 186 1.9E-5 T 06-07-2017 GTHT12_RS09795 c66c4e014cc2cdb7dd861e8633590e8b 499 PRINTS PR00475 Hexokinase family signature 5 21 1.9E-5 T 06-07-2017 GTHT12_RS09795 c66c4e014cc2cdb7dd861e8633590e8b 499 PRINTS PR00475 Hexokinase family signature 425 441 1.9E-5 T 06-07-2017 GTHT12_RS09795 c66c4e014cc2cdb7dd861e8633590e8b 499 SUPERFAMILY SSF53067 249 490 6.11E-68 T 06-07-2017 GTHT12_RS09795 c66c4e014cc2cdb7dd861e8633590e8b 499 TIGRFAM TIGR01312 XylB: xylulokinase 5 484 4.3E-187 T 06-07-2017 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 GTHT12_RS09795 c66c4e014cc2cdb7dd861e8633590e8b 499 Gene3D G3DSA:3.30.420.40 250 491 4.0E-59 T 06-07-2017 GTHT12_RS09795 c66c4e014cc2cdb7dd861e8633590e8b 499 SUPERFAMILY SSF53067 3 249 1.02E-77 T 06-07-2017 GTHT12_RS09795 c66c4e014cc2cdb7dd861e8633590e8b 499 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 257 441 1.2E-36 T 06-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 GTHT12_RS09795 c66c4e014cc2cdb7dd861e8633590e8b 499 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 132 144 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 GTHT12_RS09795 c66c4e014cc2cdb7dd861e8633590e8b 499 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 355 375 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 GTHT12_RS09795 c66c4e014cc2cdb7dd861e8633590e8b 499 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 247 7.1E-68 T 06-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 GTHT12_RS13860 7a458dbbe842682da3dabba018be622a 197 SUPERFAMILY SSF52016 1 190 3.92E-59 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel GTHT12_RS13860 7a458dbbe842682da3dabba018be622a 197 Gene3D G3DSA:3.20.19.10 1 193 8.9E-48 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel GTHT12_RS13860 7a458dbbe842682da3dabba018be622a 197 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 197 41.972 T 06-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 GTHT12_RS13860 7a458dbbe842682da3dabba018be622a 197 Pfam PF00694 Aconitase C-terminal domain 1 123 3.9E-36 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 GTHT12_RS13860 7a458dbbe842682da3dabba018be622a 197 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 186 1.6E-80 T 06-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 GTHT12_RS13195 81948c04f2a4a7b6b4f88180cd46bdb4 272 PIRSF PIRSF000193 1 266 4.0E-62 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 GTHT12_RS13195 81948c04f2a4a7b6b4f88180cd46bdb4 272 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 267 16.592 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 GTHT12_RS13195 81948c04f2a4a7b6b4f88180cd46bdb4 272 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 97 3.9E-18 T 06-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal GTHT12_RS13195 81948c04f2a4a7b6b4f88180cd46bdb4 272 Gene3D G3DSA:1.10.3730.10 163 260 8.4E-16 T 06-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 GTHT12_RS13195 81948c04f2a4a7b6b4f88180cd46bdb4 272 SUPERFAMILY SSF51735 1 157 9.39E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS13195 81948c04f2a4a7b6b4f88180cd46bdb4 272 SUPERFAMILY SSF48179 159 262 7.48E-19 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GTHT12_RS13195 81948c04f2a4a7b6b4f88180cd46bdb4 272 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 220 242 - T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 GTHT12_RS13195 81948c04f2a4a7b6b4f88180cd46bdb4 272 Gene3D G3DSA:3.40.50.720 1 152 8.1E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS13195 81948c04f2a4a7b6b4f88180cd46bdb4 272 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 164 260 6.9E-16 T 06-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 GTHT12_RS06240 72de975c41acff412b3750bc9515966f 245 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 24 221 2.0E-74 T 06-07-2017 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 GTHT12_RS06240 72de975c41acff412b3750bc9515966f 245 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 245 116.708 T 06-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 GTHT12_RS06240 72de975c41acff412b3750bc9515966f 245 SUPERFAMILY SSF75217 2 243 1.37E-104 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases GTHT12_RS06240 72de975c41acff412b3750bc9515966f 245 Gene3D G3DSA:1.10.1270.20 161 243 1.6E-35 T 06-07-2017 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 GTHT12_RS06240 72de975c41acff412b3750bc9515966f 245 PIRSF PIRSF000386 2 245 1.7E-108 T 06-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 GTHT12_RS06240 72de975c41acff412b3750bc9515966f 245 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 2 234 7.3E-105 T 06-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 GTHT12_RS06240 72de975c41acff412b3750bc9515966f 245 Gene3D G3DSA:3.40.1280.10 1 160 1.4E-70 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal GTHT12_RS06930 0fb653614f503d474a16af8330a6a394 118 SUPERFAMILY SSF52172 3 118 2.28E-38 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS06930 0fb653614f503d474a16af8330a6a394 118 Gene3D G3DSA:3.40.50.2300 2 118 6.2E-39 T 06-07-2017 GTHT12_RS06930 0fb653614f503d474a16af8330a6a394 118 Pfam PF00072 Response regulator receiver domain 4 114 9.2E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS06930 0fb653614f503d474a16af8330a6a394 118 SMART SM00448 2 114 1.3E-34 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS16050 539cb99bd056f10dd3ece7b5edf63229 659 Pfam PF04851 Type III restriction enzyme, res subunit 13 138 1.6E-10 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 GTHT12_RS16050 539cb99bd056f10dd3ece7b5edf63229 659 SMART SM00487 9 425 2.0E-27 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain GTHT12_RS16050 539cb99bd056f10dd3ece7b5edf63229 659 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 4 656 0.0 T 06-07-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 GTHT12_RS16050 539cb99bd056f10dd3ece7b5edf63229 659 SMART SM00490 459 545 5.7E-23 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS16050 539cb99bd056f10dd3ece7b5edf63229 659 Hamap MF_00204 UvrABC system protein B [uvrB]. 3 658 45.847 T 06-07-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 GTHT12_RS16050 539cb99bd056f10dd3ece7b5edf63229 659 Pfam PF02151 UvrB/uvrC motif 623 657 2.9E-10 T 06-07-2017 IPR001943 UVR domain GO:0005515 GTHT12_RS16050 539cb99bd056f10dd3ece7b5edf63229 659 Gene3D G3DSA:3.40.50.300 388 409 4.7E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16050 539cb99bd056f10dd3ece7b5edf63229 659 Gene3D G3DSA:3.40.50.300 278 338 4.7E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16050 539cb99bd056f10dd3ece7b5edf63229 659 Gene3D G3DSA:3.40.50.300 5 89 4.7E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16050 539cb99bd056f10dd3ece7b5edf63229 659 Gene3D G3DSA:3.30.2060.10 159 230 7.9E-13 T 06-07-2017 GTHT12_RS16050 539cb99bd056f10dd3ece7b5edf63229 659 SUPERFAMILY SSF46600 612 657 1.83E-11 T 06-07-2017 IPR001943 UVR domain GO:0005515 GTHT12_RS16050 539cb99bd056f10dd3ece7b5edf63229 659 SUPERFAMILY SSF52540 4 414 1.48E-148 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16050 539cb99bd056f10dd3ece7b5edf63229 659 Gene3D G3DSA:3.40.50.300 423 580 2.2E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16050 539cb99bd056f10dd3ece7b5edf63229 659 SUPERFAMILY SSF52540 413 597 2.13E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16050 539cb99bd056f10dd3ece7b5edf63229 659 Gene3D G3DSA:4.10.860.10 604 657 2.1E-15 T 06-07-2017 IPR001943 UVR domain GO:0005515 GTHT12_RS16050 539cb99bd056f10dd3ece7b5edf63229 659 Pfam PF00271 Helicase conserved C-terminal domain 432 544 4.5E-22 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS16050 539cb99bd056f10dd3ece7b5edf63229 659 Pfam PF12344 Ultra-violet resistance protein B 551 593 5.7E-22 T 06-07-2017 IPR024759 UvrB, YAD/RRR-motif-containing domain GTHT12_RS01620 5ac783d3de19f77177f55fabc3a1ae16 742 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 742 337.361 T 06-07-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GTHT12_RS01620 5ac783d3de19f77177f55fabc3a1ae16 742 PIRSF PIRSF001587 8 741 0.0 T 06-07-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GTHT12_RS01620 5ac783d3de19f77177f55fabc3a1ae16 742 SUPERFAMILY SSF56042 206 430 6.28E-59 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain GTHT12_RS01620 5ac783d3de19f77177f55fabc3a1ae16 742 SUPERFAMILY SSF56042 572 738 9.72E-38 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain GTHT12_RS01620 5ac783d3de19f77177f55fabc3a1ae16 742 Gene3D G3DSA:3.90.650.10 218 358 3.1E-4 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain GTHT12_RS01620 5ac783d3de19f77177f55fabc3a1ae16 742 SUPERFAMILY SSF55326 18 200 7.63E-52 T 06-07-2017 GTHT12_RS01620 5ac783d3de19f77177f55fabc3a1ae16 742 SUPERFAMILY SSF55326 403 570 3.66E-60 T 06-07-2017 GTHT12_RS01620 5ac783d3de19f77177f55fabc3a1ae16 742 Pfam PF02769 AIR synthase related protein, C-terminal domain 207 358 5.2E-35 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain GTHT12_RS01620 5ac783d3de19f77177f55fabc3a1ae16 742 Pfam PF02769 AIR synthase related protein, C-terminal domain 575 707 8.7E-13 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain GTHT12_RS01620 5ac783d3de19f77177f55fabc3a1ae16 742 Gene3D G3DSA:3.30.1330.10 55 200 1.6E-52 T 06-07-2017 IPR016188 PurM-like, N-terminal domain GTHT12_RS01620 5ac783d3de19f77177f55fabc3a1ae16 742 Gene3D G3DSA:3.30.1330.10 418 565 1.1E-64 T 06-07-2017 IPR016188 PurM-like, N-terminal domain GTHT12_RS01620 5ac783d3de19f77177f55fabc3a1ae16 742 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 23 737 0.0 T 06-07-2017 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GTHT12_RS01620 5ac783d3de19f77177f55fabc3a1ae16 742 Pfam PF00586 AIR synthase related protein, N-terminal domain 445 562 1.3E-26 T 06-07-2017 IPR016188 PurM-like, N-terminal domain GTHT12_RS01620 5ac783d3de19f77177f55fabc3a1ae16 742 Pfam PF00586 AIR synthase related protein, N-terminal domain 92 194 1.1E-24 T 06-07-2017 IPR016188 PurM-like, N-terminal domain GTHT12_RS05335 0fe25b51bb7c09b8ae6d589409bb6f92 425 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 312 415 3.3E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS05335 0fe25b51bb7c09b8ae6d589409bb6f92 425 SMART SM00387 312 418 1.6E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS05335 0fe25b51bb7c09b8ae6d589409bb6f92 425 Pfam PF08448 PAS fold 80 194 1.6E-15 T 06-07-2017 IPR013656 PAS fold-4 GTHT12_RS05335 0fe25b51bb7c09b8ae6d589409bb6f92 425 Pfam PF00512 His Kinase A (phospho-acceptor) domain 208 269 8.4E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS05335 0fe25b51bb7c09b8ae6d589409bb6f92 425 SUPERFAMILY SSF55785 66 190 1.92E-15 T 06-07-2017 IPR000014 PAS domain GTHT12_RS05335 0fe25b51bb7c09b8ae6d589409bb6f92 425 SMART SM00388 207 270 4.5E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS05335 0fe25b51bb7c09b8ae6d589409bb6f92 425 Gene3D G3DSA:3.30.450.20 68 192 1.0E-14 T 06-07-2017 GTHT12_RS05335 0fe25b51bb7c09b8ae6d589409bb6f92 425 SUPERFAMILY SSF55874 260 415 6.42E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS05335 0fe25b51bb7c09b8ae6d589409bb6f92 425 Gene3D G3DSA:1.10.287.130 203 266 4.9E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS05335 0fe25b51bb7c09b8ae6d589409bb6f92 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 415 2.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS05335 0fe25b51bb7c09b8ae6d589409bb6f92 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 396 2.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS05335 0fe25b51bb7c09b8ae6d589409bb6f92 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 349 363 2.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS05335 0fe25b51bb7c09b8ae6d589409bb6f92 425 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 377 2.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS05335 0fe25b51bb7c09b8ae6d589409bb6f92 425 Gene3D G3DSA:3.30.565.10 271 415 2.2E-40 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS05335 0fe25b51bb7c09b8ae6d589409bb6f92 425 SUPERFAMILY SSF47384 202 270 4.71E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS05335 0fe25b51bb7c09b8ae6d589409bb6f92 425 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 69 198 2.0E-11 T 06-07-2017 IPR000014 PAS domain GTHT12_RS09270 9c0b43923ca8a7f1e1eb36ec7f6522df 411 Pfam PF07687 Peptidase dimerisation domain 209 309 1.5E-14 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS09270 9c0b43923ca8a7f1e1eb36ec7f6522df 411 SUPERFAMILY SSF55031 211 322 9.42E-46 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS09270 9c0b43923ca8a7f1e1eb36ec7f6522df 411 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 74 83 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 GTHT12_RS09270 9c0b43923ca8a7f1e1eb36ec7f6522df 411 PIRSF PIRSF037215 1 410 6.7E-203 T 06-07-2017 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 GTHT12_RS09270 9c0b43923ca8a7f1e1eb36ec7f6522df 411 Pfam PF01546 Peptidase family M20/M25/M40 141 404 7.9E-15 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 GTHT12_RS09270 9c0b43923ca8a7f1e1eb36ec7f6522df 411 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 140 179 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 GTHT12_RS09270 9c0b43923ca8a7f1e1eb36ec7f6522df 411 SUPERFAMILY SSF53187 324 406 4.28E-87 T 06-07-2017 GTHT12_RS09270 9c0b43923ca8a7f1e1eb36ec7f6522df 411 SUPERFAMILY SSF53187 3 212 4.28E-87 T 06-07-2017 GTHT12_RS09270 9c0b43923ca8a7f1e1eb36ec7f6522df 411 Gene3D G3DSA:3.30.70.360 212 321 1.2E-49 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS09270 9c0b43923ca8a7f1e1eb36ec7f6522df 411 Gene3D G3DSA:3.40.630.10 324 409 6.0E-133 T 06-07-2017 GTHT12_RS09270 9c0b43923ca8a7f1e1eb36ec7f6522df 411 Gene3D G3DSA:3.40.630.10 1 211 6.0E-133 T 06-07-2017 GTHT12_RS09270 9c0b43923ca8a7f1e1eb36ec7f6522df 411 Hamap MF_00550 Peptidase T [pepT]. 2 406 62.097 T 06-07-2017 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 GTHT12_RS09270 9c0b43923ca8a7f1e1eb36ec7f6522df 411 TIGRFAM TIGR01882 peptidase-T: peptidase T 3 409 3.7E-213 T 06-07-2017 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 GTHT12_RS10395 ab69268e400088cd99985ecf3233da42 696 SUPERFAMILY SSF52794 417 498 8.89E-11 T 06-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 GTHT12_RS10395 ab69268e400088cd99985ecf3233da42 696 Gene3D G3DSA:1.10.1790.10 203 300 2.0E-21 T 06-07-2017 IPR011608 PRD domain GO:0006355 GTHT12_RS10395 ab69268e400088cd99985ecf3233da42 696 Gene3D G3DSA:1.10.1790.10 321 412 1.0E-20 T 06-07-2017 IPR011608 PRD domain GO:0006355 GTHT12_RS10395 ab69268e400088cd99985ecf3233da42 696 SUPERFAMILY SSF46785 1 66 6.39E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS10395 ab69268e400088cd99985ecf3233da42 696 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 546 680 3.9E-14 T 06-07-2017 IPR002178 PTS EIIA type-2 domain GTHT12_RS10395 ab69268e400088cd99985ecf3233da42 696 SUPERFAMILY SSF63520 320 413 3.4E-21 T 06-07-2017 IPR011608 PRD domain GO:0006355 GTHT12_RS10395 ab69268e400088cd99985ecf3233da42 696 SUPERFAMILY SSF55804 546 680 1.44E-19 T 06-07-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 GTHT12_RS10395 ab69268e400088cd99985ecf3233da42 696 Pfam PF08279 HTH domain 6 64 4.8E-11 T 06-07-2017 IPR013196 Helix-turn-helix, type 11 GTHT12_RS10395 ab69268e400088cd99985ecf3233da42 696 Pfam PF05043 Mga helix-turn-helix domain 91 165 8.0E-6 T 06-07-2017 IPR007737 Mga helix-turn-helix domain GTHT12_RS10395 ab69268e400088cd99985ecf3233da42 696 Gene3D G3DSA:1.10.10.10 84 153 5.5E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS10395 ab69268e400088cd99985ecf3233da42 696 Gene3D G3DSA:1.10.10.10 4 67 1.2E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS10395 ab69268e400088cd99985ecf3233da42 696 SUPERFAMILY SSF63520 198 302 6.8E-24 T 06-07-2017 IPR011608 PRD domain GO:0006355 GTHT12_RS10395 ab69268e400088cd99985ecf3233da42 696 Gene3D G3DSA:3.40.930.10 546 685 2.8E-18 T 06-07-2017 IPR002178 PTS EIIA type-2 domain GTHT12_RS10395 ab69268e400088cd99985ecf3233da42 696 Gene3D G3DSA:3.40.50.270 420 499 1.3E-7 T 06-07-2017 GTHT12_RS10395 ab69268e400088cd99985ecf3233da42 696 Pfam PF00874 PRD domain 212 298 9.0E-20 T 06-07-2017 IPR011608 PRD domain GO:0006355 GTHT12_RS10395 ab69268e400088cd99985ecf3233da42 696 Pfam PF00874 PRD domain 321 409 3.3E-19 T 06-07-2017 IPR011608 PRD domain GO:0006355 GTHT12_RS10395 ab69268e400088cd99985ecf3233da42 696 SUPERFAMILY SSF46785 88 152 7.61E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS17740 d888df290a157b0b770bcdaa2e57288b 432 Pfam PF01966 HD domain 60 179 3.2E-16 T 06-07-2017 IPR006674 HD domain GTHT12_RS17740 d888df290a157b0b770bcdaa2e57288b 432 SUPERFAMILY SSF109604 7 413 4.19E-121 T 06-07-2017 GTHT12_RS17740 d888df290a157b0b770bcdaa2e57288b 432 SMART SM00471 56 186 1.9E-13 T 06-07-2017 IPR003607 HD/PDEase domain GTHT12_RS17740 d888df290a157b0b770bcdaa2e57288b 432 Gene3D G3DSA:1.10.3210.10 8 256 2.5E-87 T 06-07-2017 IPR006674 HD domain GTHT12_RS11730 2950f27c40847e26a6e5831e54fe218f 343 Gene3D G3DSA:3.40.50.720 1 184 1.3E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS11730 2950f27c40847e26a6e5831e54fe218f 343 PIRSF PIRSF000114 1 333 9.2E-113 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 GTHT12_RS11730 2950f27c40847e26a6e5831e54fe218f 343 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 189 210 - T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 GTHT12_RS11730 2950f27c40847e26a6e5831e54fe218f 343 Gene3D G3DSA:1.10.1040.10 185 327 4.7E-62 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 GTHT12_RS11730 2950f27c40847e26a6e5831e54fe218f 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 6 23 1.3E-46 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 GTHT12_RS11730 2950f27c40847e26a6e5831e54fe218f 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 133 153 1.3E-46 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 GTHT12_RS11730 2950f27c40847e26a6e5831e54fe218f 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 174 198 1.3E-46 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 GTHT12_RS11730 2950f27c40847e26a6e5831e54fe218f 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 56 83 1.3E-46 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 GTHT12_RS11730 2950f27c40847e26a6e5831e54fe218f 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 199 223 1.3E-46 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 GTHT12_RS11730 2950f27c40847e26a6e5831e54fe218f 343 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 239 256 1.3E-46 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 GTHT12_RS11730 2950f27c40847e26a6e5831e54fe218f 343 SUPERFAMILY SSF48179 181 333 8.67E-61 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GTHT12_RS11730 2950f27c40847e26a6e5831e54fe218f 343 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 181 321 3.5E-56 T 06-07-2017 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 GTHT12_RS11730 2950f27c40847e26a6e5831e54fe218f 343 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3 160 3.2E-55 T 06-07-2017 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 GTHT12_RS11730 2950f27c40847e26a6e5831e54fe218f 343 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 2 323 39.774 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 GTHT12_RS11730 2950f27c40847e26a6e5831e54fe218f 343 SUPERFAMILY SSF51735 3 179 1.72E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS12005 abd28ac00eff19b79545277b0bb5ea54 254 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 3 243 42.456 T 06-07-2017 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 GTHT12_RS12005 abd28ac00eff19b79545277b0bb5ea54 254 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 15 226 1.0E-19 T 06-07-2017 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 GTHT12_RS12005 abd28ac00eff19b79545277b0bb5ea54 254 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 3 243 2.9E-89 T 06-07-2017 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 GTHT12_RS12005 abd28ac00eff19b79545277b0bb5ea54 254 Gene3D G3DSA:3.40.50.1360 3 243 5.4E-95 T 06-07-2017 GTHT12_RS12005 abd28ac00eff19b79545277b0bb5ea54 254 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 122 140 - T 06-07-2017 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 GTHT12_RS12005 abd28ac00eff19b79545277b0bb5ea54 254 SUPERFAMILY SSF100950 3 243 4.19E-91 T 06-07-2017 GTHT12_RS08075 b61d858a32a5857bc4bb4a8f1a5efe2b 312 Gene3D G3DSA:1.20.58.340 237 312 8.1E-22 T 06-07-2017 GTHT12_RS08075 b61d858a32a5857bc4bb4a8f1a5efe2b 312 SUPERFAMILY SSF144083 248 309 2.62E-15 T 06-07-2017 GTHT12_RS08075 b61d858a32a5857bc4bb4a8f1a5efe2b 312 Pfam PF01544 CorA-like Mg2+ transporter protein 22 310 8.9E-65 T 06-07-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 GTHT12_RS08075 b61d858a32a5857bc4bb4a8f1a5efe2b 312 Gene3D G3DSA:1.20.58.340 142 234 3.4E-4 T 06-07-2017 GTHT12_RS08075 b61d858a32a5857bc4bb4a8f1a5efe2b 312 Gene3D G3DSA:3.30.460.20 21 114 1.7E-9 T 06-07-2017 GTHT12_RS08075 b61d858a32a5857bc4bb4a8f1a5efe2b 312 SUPERFAMILY SSF143865 3 247 4.71E-58 T 06-07-2017 GTHT12_RS14905 683bca7d5e1d4900844cf50611bef592 309 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 25 293 3.0E-40 T 06-07-2017 GTHT12_RS14905 683bca7d5e1d4900844cf50611bef592 309 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 16 303 19.689 T 06-07-2017 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 GTHT12_RS14905 683bca7d5e1d4900844cf50611bef592 309 PIRSF PIRSF005355 9 308 9.7E-91 T 06-07-2017 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 GTHT12_RS14905 683bca7d5e1d4900844cf50611bef592 309 Pfam PF01040 UbiA prenyltransferase family 33 272 2.2E-37 T 06-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 GTHT12_RS18760 81770c975fd4ed7d00009657a6da634c 176 Gene3D G3DSA:1.10.10.10 88 159 3.2E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS18760 81770c975fd4ed7d00009657a6da634c 176 Pfam PF04545 Sigma-70, region 4 102 149 5.5E-10 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS18760 81770c975fd4ed7d00009657a6da634c 176 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 149 2.9E-14 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS18760 81770c975fd4ed7d00009657a6da634c 176 SUPERFAMILY SSF88659 90 155 8.78E-17 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS14835 c77d42b353848f4b11049aaacf28b6fd 71 Pfam PF12606 Tumour necrosis factor receptor superfamily member 19 20 64 1.9E-17 T 06-07-2017 IPR022248 TNF receptor family, RELT GTHT12_RS14325 07479badf77489ebbddf77108800df4e 254 Gene3D G3DSA:3.40.50.720 2 246 2.4E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS14325 07479badf77489ebbddf77108800df4e 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 5.0E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS14325 07479badf77489ebbddf77108800df4e 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 5.0E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS14325 07479badf77489ebbddf77108800df4e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.4E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS14325 07479badf77489ebbddf77108800df4e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.4E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS14325 07479badf77489ebbddf77108800df4e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.4E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS14325 07479badf77489ebbddf77108800df4e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.4E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS14325 07479badf77489ebbddf77108800df4e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.4E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS14325 07479badf77489ebbddf77108800df4e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.4E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS14325 07479badf77489ebbddf77108800df4e 254 SUPERFAMILY SSF51735 2 247 5.63E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS14325 07479badf77489ebbddf77108800df4e 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 246 7.8E-52 T 06-07-2017 GTHT12_RS11830 c3951e976336ddcd9417ce63bc4ed746 330 Gene3D G3DSA:3.50.50.60 5 124 2.0E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS11830 c3951e976336ddcd9417ce63bc4ed746 330 Gene3D G3DSA:3.50.50.60 125 296 3.5E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS11830 c3951e976336ddcd9417ce63bc4ed746 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 293 3.2E-12 T 06-07-2017 GTHT12_RS11830 c3951e976336ddcd9417ce63bc4ed746 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 242 258 3.2E-12 T 06-07-2017 GTHT12_RS11830 c3951e976336ddcd9417ce63bc4ed746 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 3.2E-12 T 06-07-2017 GTHT12_RS11830 c3951e976336ddcd9417ce63bc4ed746 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.2E-12 T 06-07-2017 GTHT12_RS11830 c3951e976336ddcd9417ce63bc4ed746 330 TIGRFAM TIGR04018 Bthiol_YpdA: putative bacillithiol system oxidoreductase, YpdA family 6 319 2.9E-146 T 06-07-2017 IPR023856 Bacillithiol biosynthesis thiol disulphide oxidoreductase, YpdA GTHT12_RS11830 c3951e976336ddcd9417ce63bc4ed746 330 SUPERFAMILY SSF51905 5 320 8.6E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS11830 c3951e976336ddcd9417ce63bc4ed746 330 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 290 1.3E-105 T 06-07-2017 GTHT12_RS11830 c3951e976336ddcd9417ce63bc4ed746 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 3.5E-16 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS11830 c3951e976336ddcd9417ce63bc4ed746 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 120 128 3.5E-16 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS11830 c3951e976336ddcd9417ce63bc4ed746 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 281 299 3.5E-16 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS11830 c3951e976336ddcd9417ce63bc4ed746 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 155 179 3.5E-16 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS11205 0c660828ace9fe4e15d6774689c99c9e 218 Pfam PF07853 Protein of unknown function (DUF1648) 10 58 9.1E-18 T 06-07-2017 IPR012867 Domain of unknown function DUF1648 GTHT12_RS11205 0c660828ace9fe4e15d6774689c99c9e 218 Pfam PF13630 SdpI/YhfL protein family 134 198 5.6E-21 T 06-07-2017 IPR025962 SdpI/YhfL protein family GTHT12_RS11205 0c660828ace9fe4e15d6774689c99c9e 218 PIRSF PIRSF038959 1 216 8.3E-50 T 06-07-2017 IPR026272 Immunity protein SdpI GTHT12_RS17235 ca86169fd9b8e7d4625eb77c11c5c1f9 376 SUPERFAMILY SSF53756 133 370 4.49E-73 T 06-07-2017 GTHT12_RS17235 ca86169fd9b8e7d4625eb77c11c5c1f9 376 SUPERFAMILY SSF53756 2 106 4.49E-73 T 06-07-2017 GTHT12_RS17235 ca86169fd9b8e7d4625eb77c11c5c1f9 376 Pfam PF13439 Glycosyltransferase Family 4 38 181 1.8E-12 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 GTHT12_RS17235 ca86169fd9b8e7d4625eb77c11c5c1f9 376 Gene3D G3DSA:3.40.50.2000 193 340 1.9E-29 T 06-07-2017 GTHT12_RS17235 ca86169fd9b8e7d4625eb77c11c5c1f9 376 Pfam PF00534 Glycosyl transferases group 1 182 334 3.6E-37 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 GTHT12_RS00840 aab0afd8f004b093a1541e445d3d1424 238 SMART SM00646 116 227 4.1E-36 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 GTHT12_RS00840 aab0afd8f004b093a1541e445d3d1424 238 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 44 227 1.9E-50 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 GTHT12_RS00840 aab0afd8f004b093a1541e445d3d1424 238 SUPERFAMILY SSF53187 42 231 8.48E-53 T 06-07-2017 GTHT12_RS00840 aab0afd8f004b093a1541e445d3d1424 238 TIGRFAM TIGR02883 spore_cwlD: N-acetylmuramoyl-L-alanine amidase CwlD 42 229 4.2E-84 T 06-07-2017 IPR014234 N-acetylmuramoyl-L-alanine amidase CwlD GTHT12_RS00840 aab0afd8f004b093a1541e445d3d1424 238 Gene3D G3DSA:3.40.630.40 42 231 3.4E-57 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 GTHT12_RS14660 cc1029c1ab57c3369a46cf144dd6bd21 283 Gene3D G3DSA:3.60.15.10 1 279 6.3E-47 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS14660 cc1029c1ab57c3369a46cf144dd6bd21 283 SMART SM00849 50 257 5.7E-16 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS14660 cc1029c1ab57c3369a46cf144dd6bd21 283 SUPERFAMILY SSF56281 3 267 6.63E-42 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS14660 cc1029c1ab57c3369a46cf144dd6bd21 283 Pfam PF00753 Metallo-beta-lactamase superfamily 54 235 1.2E-13 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS11955 16414b71637d173d8b039f63758b9028 185 Gene3D G3DSA:3.40.50.300 2 176 1.3E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11955 16414b71637d173d8b039f63758b9028 185 PIRSF PIRSF006135 1 182 1.7E-42 T 06-07-2017 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 GTHT12_RS11955 16414b71637d173d8b039f63758b9028 185 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 3 175 6.3E-42 T 06-07-2017 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 GTHT12_RS11955 16414b71637d173d8b039f63758b9028 185 SUPERFAMILY SSF52540 2 178 2.77E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17470 3e788abaa50edf110dc992d4e2a4e2f9 133 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 86 131 2.2E-17 T 06-07-2017 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210 GTHT12_RS17470 3e788abaa50edf110dc992d4e2a4e2f9 133 Gene3D G3DSA:1.20.5.440 89 133 1.9E-22 T 06-07-2017 GTHT12_RS17470 3e788abaa50edf110dc992d4e2a4e2f9 133 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 88 4.0E-37 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 GTHT12_RS17470 3e788abaa50edf110dc992d4e2a4e2f9 133 SUPERFAMILY SSF51344 2 84 4.05E-25 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 GTHT12_RS17470 3e788abaa50edf110dc992d4e2a4e2f9 133 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 82 2.2E-30 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 GTHT12_RS17470 3e788abaa50edf110dc992d4e2a4e2f9 133 SUPERFAMILY SSF46604 86 130 2.3E-10 T 06-07-2017 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210 GTHT12_RS17470 3e788abaa50edf110dc992d4e2a4e2f9 133 Gene3D G3DSA:2.60.15.10 1 88 1.8E-31 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 GTHT12_RS17470 3e788abaa50edf110dc992d4e2a4e2f9 133 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 130 9.6E-42 T 06-07-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 GTHT12_RS17470 3e788abaa50edf110dc992d4e2a4e2f9 133 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 129 24.548 T 06-07-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 GTHT12_RS02420 a9383ace02fd48ea871e2eaa910ca1e3 213 Pfam PF14824 Sirohaem biosynthesis protein central 117 144 1.4E-12 T 06-07-2017 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 GTHT12_RS02420 a9383ace02fd48ea871e2eaa910ca1e3 213 Gene3D G3DSA:3.30.160.110 111 145 1.9E-17 T 06-07-2017 GTHT12_RS02420 a9383ace02fd48ea871e2eaa910ca1e3 213 SUPERFAMILY SSF51735 3 110 6.76E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS02420 a9383ace02fd48ea871e2eaa910ca1e3 213 Gene3D G3DSA:3.40.50.720 3 110 3.6E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS02420 a9383ace02fd48ea871e2eaa910ca1e3 213 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 3 186 2.2E-50 T 06-07-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 GTHT12_RS02420 a9383ace02fd48ea871e2eaa910ca1e3 213 SUPERFAMILY SSF75615 112 186 4.97E-21 T 06-07-2017 GTHT12_RS02420 a9383ace02fd48ea871e2eaa910ca1e3 213 Pfam PF13241 Putative NAD(P)-binding 6 113 2.6E-30 T 06-07-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 GTHT12_RS18205 030096ae9f73ad100f05455bd7f738f8 253 Pfam PF13614 AAA domain 2 177 3.7E-73 T 06-07-2017 IPR025669 AAA domain GTHT12_RS18205 030096ae9f73ad100f05455bd7f738f8 253 Gene3D G3DSA:3.40.50.300 3 252 4.1E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18205 030096ae9f73ad100f05455bd7f738f8 253 SUPERFAMILY SSF52540 2 252 2.26E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16925 cd48f88288cdcf81d94ca2f6cd69f646 338 Gene3D G3DSA:3.40.718.10 3 329 2.8E-118 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 GTHT12_RS16925 cd48f88288cdcf81d94ca2f6cd69f646 338 SUPERFAMILY SSF53659 6 332 1.17E-102 T 06-07-2017 GTHT12_RS16925 cd48f88288cdcf81d94ca2f6cd69f646 338 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 9 329 1.5E-99 T 06-07-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 GTHT12_RS16925 cd48f88288cdcf81d94ca2f6cd69f646 338 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 36 326 4.7E-99 T 06-07-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 GTHT12_RS16925 cd48f88288cdcf81d94ca2f6cd69f646 338 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 5 330 33.264 T 06-07-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 GTHT12_RS10645 30ca2069a810ced55fd752131530bab7 291 Pfam PF08223 PaaX-like protein C-terminal domain 89 256 8.1E-50 T 06-07-2017 IPR013225 PaaX-like, C-terminal GTHT12_RS10645 30ca2069a810ced55fd752131530bab7 291 PIRSF PIRSF020623 1 285 7.0E-83 T 06-07-2017 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 GTHT12_RS10645 30ca2069a810ced55fd752131530bab7 291 Pfam PF07848 PaaX-like protein 3 71 6.0E-20 T 06-07-2017 IPR012906 PaaX-like, N-terminal GTHT12_RS10220 c8b1049586cd4d389c1f66cbaf0d4351 220 Gene3D G3DSA:3.20.20.70 4 211 1.3E-71 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS10220 c8b1049586cd4d389c1f66cbaf0d4351 220 Pfam PF01081 KDPG and KHG aldolase 7 199 1.1E-41 T 06-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 GTHT12_RS10220 c8b1049586cd4d389c1f66cbaf0d4351 220 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 7 206 1.4E-53 T 06-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 GTHT12_RS10220 c8b1049586cd4d389c1f66cbaf0d4351 220 SUPERFAMILY SSF51569 4 207 2.01E-58 T 06-07-2017 GTHT12_RS15910 869c7595ca455a92bb4162377e0533f0 81 SUPERFAMILY SSF52833 2 78 3.56E-22 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS15910 869c7595ca455a92bb4162377e0533f0 81 Pfam PF05768 Glutaredoxin-like domain (DUF836) 3 74 2.5E-18 T 06-07-2017 IPR008554 Glutaredoxin-like GTHT12_RS15910 869c7595ca455a92bb4162377e0533f0 81 Gene3D G3DSA:3.40.30.10 1 78 2.0E-22 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS05520 5fbfcc434bf53451f265242467ef532b 236 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 1 235 47.057 T 06-07-2017 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 GTHT12_RS05520 5fbfcc434bf53451f265242467ef532b 236 Gene3D G3DSA:2.160.10.10 90 227 7.1E-53 T 06-07-2017 GTHT12_RS05520 5fbfcc434bf53451f265242467ef532b 236 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 6 236 8.4E-124 T 06-07-2017 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 GTHT12_RS05520 5fbfcc434bf53451f265242467ef532b 236 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 4 87 3.2E-37 T 06-07-2017 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 GTHT12_RS05520 5fbfcc434bf53451f265242467ef532b 236 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 174 202 - T 06-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 GTHT12_RS05520 5fbfcc434bf53451f265242467ef532b 236 Gene3D G3DSA:3.30.70.250 1 87 2.8E-38 T 06-07-2017 GTHT12_RS05520 5fbfcc434bf53451f265242467ef532b 236 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 165 198 1.1E-9 T 06-07-2017 IPR001451 Hexapeptide repeat GTHT12_RS05520 5fbfcc434bf53451f265242467ef532b 236 SUPERFAMILY SSF51161 89 225 6.68E-52 T 06-07-2017 IPR011004 Trimeric LpxA-like GTHT12_RS05520 5fbfcc434bf53451f265242467ef532b 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 121 156 7.9E-11 T 06-07-2017 IPR001451 Hexapeptide repeat GTHT12_RS05520 5fbfcc434bf53451f265242467ef532b 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 91 119 1.8E-5 T 06-07-2017 IPR001451 Hexapeptide repeat GTHT12_RS09175 b9e49323083cb8fffb48b5a908a7d1d7 139 Gene3D G3DSA:3.40.50.720 15 134 1.2E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS09175 b9e49323083cb8fffb48b5a908a7d1d7 139 SMART SM00881 14 107 6.4E-14 T 06-07-2017 IPR003781 CoA-binding GO:0048037 GTHT12_RS09175 b9e49323083cb8fffb48b5a908a7d1d7 139 SUPERFAMILY SSF51735 9 135 1.41E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS09175 b9e49323083cb8fffb48b5a908a7d1d7 139 Pfam PF13380 CoA binding domain 19 133 2.3E-37 T 06-07-2017 IPR003781 CoA-binding GO:0048037 GTHT12_RS08660 30968e048bbfc1dccdaf5812e9676e40 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 100 120 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 GTHT12_RS08660 30968e048bbfc1dccdaf5812e9676e40 259 Gene3D G3DSA:1.10.12.10 201 259 5.9E-19 T 06-07-2017 IPR014748 Crontonase, C-terminal GTHT12_RS08660 30968e048bbfc1dccdaf5812e9676e40 259 Gene3D G3DSA:3.90.226.10 3 200 1.0E-67 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS08660 30968e048bbfc1dccdaf5812e9676e40 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 258 7.7E-63 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 GTHT12_RS08660 30968e048bbfc1dccdaf5812e9676e40 259 SUPERFAMILY SSF52096 5 258 1.05E-86 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS05160 7111f4e47a4b117cbccf8db5e04e81de 223 Gene3D G3DSA:3.40.50.620 6 213 9.8E-86 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS05160 7111f4e47a4b117cbccf8db5e04e81de 223 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 8 206 2.3E-84 T 06-07-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 GTHT12_RS05160 7111f4e47a4b117cbccf8db5e04e81de 223 PIRSF PIRSF006293 4 222 9.9E-80 T 06-07-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 GTHT12_RS05160 7111f4e47a4b117cbccf8db5e04e81de 223 SUPERFAMILY SSF52402 6 216 2.87E-70 T 06-07-2017 GTHT12_RS05160 7111f4e47a4b117cbccf8db5e04e81de 223 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 6 219 52.375 T 06-07-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 GTHT12_RS05160 7111f4e47a4b117cbccf8db5e04e81de 223 Pfam PF06508 Queuosine biosynthesis protein QueC 7 213 3.1E-86 T 06-07-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 GTHT12_RS05930 9e528eb5a46d1b938038821ee0cb3057 259 Gene3D G3DSA:1.10.10.10 203 256 3.6E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS05930 9e528eb5a46d1b938038821ee0cb3057 259 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 256 1.3E-34 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05930 9e528eb5a46d1b938038821ee0cb3057 259 Pfam PF04542 Sigma-70 region 2 42 110 5.0E-17 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05930 9e528eb5a46d1b938038821ee0cb3057 259 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 227 253 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05930 9e528eb5a46d1b938038821ee0cb3057 259 Pfam PF04539 Sigma-70 region 3 124 175 6.7E-8 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05930 9e528eb5a46d1b938038821ee0cb3057 259 TIGRFAM TIGR02850 spore_sigG: RNA polymerase sigma-G factor 4 257 4.4E-155 T 06-07-2017 IPR014212 RNA polymerase sigma-G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05930 9e528eb5a46d1b938038821ee0cb3057 259 SUPERFAMILY SSF88946 13 110 2.62E-34 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05930 9e528eb5a46d1b938038821ee0cb3057 259 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 66 79 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05930 9e528eb5a46d1b938038821ee0cb3057 259 Gene3D G3DSA:1.10.10.10 110 165 6.1E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS05930 9e528eb5a46d1b938038821ee0cb3057 259 PRINTS PR00046 Major sigma-70 factor signature 227 242 1.2E-12 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05930 9e528eb5a46d1b938038821ee0cb3057 259 PRINTS PR00046 Major sigma-70 factor signature 90 98 1.2E-12 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05930 9e528eb5a46d1b938038821ee0cb3057 259 PRINTS PR00046 Major sigma-70 factor signature 210 222 1.2E-12 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05930 9e528eb5a46d1b938038821ee0cb3057 259 PRINTS PR00046 Major sigma-70 factor signature 66 79 1.2E-12 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05930 9e528eb5a46d1b938038821ee0cb3057 259 PRINTS PR00046 Major sigma-70 factor signature 242 253 1.2E-12 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05930 9e528eb5a46d1b938038821ee0cb3057 259 Gene3D G3DSA:1.10.601.10 14 109 7.4E-35 T 06-07-2017 GTHT12_RS05930 9e528eb5a46d1b938038821ee0cb3057 259 Pfam PF04545 Sigma-70, region 4 207 253 1.0E-13 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05930 9e528eb5a46d1b938038821ee0cb3057 259 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 37 257 7.6E-83 T 06-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05930 9e528eb5a46d1b938038821ee0cb3057 259 SUPERFAMILY SSF88659 114 190 4.14E-16 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05930 9e528eb5a46d1b938038821ee0cb3057 259 SUPERFAMILY SSF88659 175 257 1.25E-16 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS05930 9e528eb5a46d1b938038821ee0cb3057 259 PIRSF PIRSF000770 14 258 1.3E-34 T 06-07-2017 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 GTHT12_RS00080 4b74ac3673a00c3ee4fb9d7a22c718b2 294 SUPERFAMILY SSF51366 18 267 1.22E-70 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 GTHT12_RS00080 4b74ac3673a00c3ee4fb9d7a22c718b2 294 ProSitePatterns PS01235 PdxS/SNZ family signature. 205 223 - T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 GTHT12_RS00080 4b74ac3673a00c3ee4fb9d7a22c718b2 294 Gene3D G3DSA:3.20.20.70 192 278 3.1E-47 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS00080 4b74ac3673a00c3ee4fb9d7a22c718b2 294 Gene3D G3DSA:3.20.20.70 24 160 3.1E-47 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS00080 4b74ac3673a00c3ee4fb9d7a22c718b2 294 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 9 294 8.4E-157 T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 GTHT12_RS00080 4b74ac3673a00c3ee4fb9d7a22c718b2 294 Pfam PF01680 SOR/SNZ family 7 212 1.0E-106 T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 GTHT12_RS00080 4b74ac3673a00c3ee4fb9d7a22c718b2 294 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 4 294 54.667 T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 GTHT12_RS00080 4b74ac3673a00c3ee4fb9d7a22c718b2 294 PIRSF PIRSF029271 2 294 2.0E-154 T 06-07-2017 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 GTHT12_RS09635 b0a5b5d84ef226581da100a0cf40dabb 623 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 06-07-2017 IPR002178 PTS EIIA type-2 domain GTHT12_RS09635 b0a5b5d84ef226581da100a0cf40dabb 623 Pfam PF02378 Phosphotransferase system, EIIC 295 564 7.0E-16 T 06-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 GTHT12_RS09635 b0a5b5d84ef226581da100a0cf40dabb 623 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 6 133 3.2E-41 T 06-07-2017 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 GTHT12_RS09635 b0a5b5d84ef226581da100a0cf40dabb 623 Gene3D G3DSA:3.40.50.2300 165 270 3.8E-44 T 06-07-2017 GTHT12_RS09635 b0a5b5d84ef226581da100a0cf40dabb 623 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 284 618 3.7E-137 T 06-07-2017 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 GTHT12_RS09635 b0a5b5d84ef226581da100a0cf40dabb 623 SUPERFAMILY SSF55804 1 146 1.09E-42 T 06-07-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 GTHT12_RS09635 b0a5b5d84ef226581da100a0cf40dabb 623 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 147 9.0E-41 T 06-07-2017 IPR002178 PTS EIIA type-2 domain GTHT12_RS09635 b0a5b5d84ef226581da100a0cf40dabb 623 Gene3D G3DSA:3.40.930.10 1 152 3.9E-53 T 06-07-2017 IPR002178 PTS EIIA type-2 domain GTHT12_RS09635 b0a5b5d84ef226581da100a0cf40dabb 623 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 171 252 8.9E-31 T 06-07-2017 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 GTHT12_RS09635 b0a5b5d84ef226581da100a0cf40dabb 623 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 171 261 2.7E-16 T 06-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 GTHT12_RS09635 b0a5b5d84ef226581da100a0cf40dabb 623 SUPERFAMILY SSF52794 168 270 2.27E-37 T 06-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 GTHT12_RS03465 fc7e12d681736e188ceac6294549c456 555 Pfam PF16657 Maltogenic Amylase, C-terminal domain 476 549 2.4E-7 T 06-07-2017 IPR032091 Maltogenic Amylase, C-terminal GTHT12_RS03465 fc7e12d681736e188ceac6294549c456 555 Gene3D G3DSA:3.20.20.80 3 104 7.8E-124 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS03465 fc7e12d681736e188ceac6294549c456 555 Gene3D G3DSA:3.20.20.80 175 475 7.8E-124 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS03465 fc7e12d681736e188ceac6294549c456 555 SUPERFAMILY SSF51445 3 473 1.23E-160 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS03465 fc7e12d681736e188ceac6294549c456 555 SMART SM00642 13 415 2.7E-170 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GTHT12_RS03465 fc7e12d681736e188ceac6294549c456 555 SUPERFAMILY SSF51011 476 553 2.93E-16 T 06-07-2017 GTHT12_RS03465 fc7e12d681736e188ceac6294549c456 555 Gene3D G3DSA:3.90.400.10 105 174 6.5E-36 T 06-07-2017 GTHT12_RS03465 fc7e12d681736e188ceac6294549c456 555 PRINTS PR00110 Alpha-amylase signature 316 328 2.3E-5 T 06-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 GTHT12_RS03465 fc7e12d681736e188ceac6294549c456 555 PRINTS PR00110 Alpha-amylase signature 193 204 2.3E-5 T 06-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 GTHT12_RS03465 fc7e12d681736e188ceac6294549c456 555 PRINTS PR00110 Alpha-amylase signature 92 103 2.3E-5 T 06-07-2017 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 GTHT12_RS03465 fc7e12d681736e188ceac6294549c456 555 Gene3D G3DSA:2.60.40.1180 477 552 1.6E-19 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta GTHT12_RS03465 fc7e12d681736e188ceac6294549c456 555 Pfam PF00128 Alpha amylase, catalytic domain 28 373 1.6E-118 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GTHT12_RS09040 66ad29cb77badd65f6a826ffbafc7789 140 Gene3D G3DSA:3.40.50.270 4 137 2.4E-50 T 06-07-2017 GTHT12_RS09040 66ad29cb77badd65f6a826ffbafc7789 140 Hamap MF_01624 Protein ArsC [arsC]. 2 138 43.516 T 06-07-2017 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 GTHT12_RS09040 66ad29cb77badd65f6a826ffbafc7789 140 SUPERFAMILY SSF52788 7 137 8.77E-48 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily GTHT12_RS09040 66ad29cb77badd65f6a826ffbafc7789 140 TIGRFAM TIGR02691 arsC_pI258_fam: arsenate reductase (thioredoxin) 7 135 3.0E-74 T 06-07-2017 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 GTHT12_RS09040 66ad29cb77badd65f6a826ffbafc7789 140 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 135 5.8E-25 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily GTHT12_RS09040 66ad29cb77badd65f6a826ffbafc7789 140 SMART SM00226 5 138 3.9E-65 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily GTHT12_RS05030 15d0623a0f4fe34e9d553abe5c050f65 396 Pfam PF01636 Phosphotransferase enzyme family 36 269 6.5E-14 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase GTHT12_RS05030 15d0623a0f4fe34e9d553abe5c050f65 396 Hamap MF_01683 Methylthioribose kinase [mtnK]. 1 396 203.02 T 06-07-2017 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 GTHT12_RS05030 15d0623a0f4fe34e9d553abe5c050f65 396 SUPERFAMILY SSF56112 6 392 1.39E-96 T 06-07-2017 IPR011009 Protein kinase-like domain GTHT12_RS05030 15d0623a0f4fe34e9d553abe5c050f65 396 TIGRFAM TIGR01767 MTRK: S-methyl-5-thioribose kinase 36 392 1.8E-154 T 06-07-2017 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 GTHT12_RS05030 15d0623a0f4fe34e9d553abe5c050f65 396 Gene3D G3DSA:3.90.1200.10 98 272 4.0E-14 T 06-07-2017 GTHT12_RS05030 15d0623a0f4fe34e9d553abe5c050f65 396 PIRSF PIRSF031134 4 396 1.1E-161 T 06-07-2017 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 GTHT12_RS05175 26841184c57ed2607d875f72dde4f476 165 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 165 72.049 T 06-07-2017 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 GTHT12_RS05175 26841184c57ed2607d875f72dde4f476 165 PIRSF PIRSF027377 7 147 3.8E-62 T 06-07-2017 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 GTHT12_RS05175 26841184c57ed2607d875f72dde4f476 165 Gene3D G3DSA:3.30.1130.10 19 148 6.3E-56 T 06-07-2017 GTHT12_RS05175 26841184c57ed2607d875f72dde4f476 165 SUPERFAMILY SSF55620 28 134 3.56E-29 T 06-07-2017 GTHT12_RS05175 26841184c57ed2607d875f72dde4f476 165 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 28 137 7.1E-55 T 06-07-2017 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 GTHT12_RS05175 26841184c57ed2607d875f72dde4f476 165 Pfam PF14489 QueF-like protein 62 138 1.7E-35 T 06-07-2017 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 GTHT12_RS01095 d936873d49f0c2a26e1251a4ab1274de 74 Gene3D G3DSA:1.10.260.40 1 69 7.8E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS01095 d936873d49f0c2a26e1251a4ab1274de 74 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 66 3.3E-24 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GTHT12_RS01095 d936873d49f0c2a26e1251a4ab1274de 74 SMART SM00530 6 62 5.3E-7 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GTHT12_RS01095 d936873d49f0c2a26e1251a4ab1274de 74 SUPERFAMILY SSF47413 1 69 2.53E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS07985 6f6d4b6afda44f14caed0cbdf6da5660 229 SUPERFAMILY SSF52540 3 225 1.18E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07985 6f6d4b6afda44f14caed0cbdf6da5660 229 Gene3D G3DSA:3.40.50.300 2 225 6.9E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07985 6f6d4b6afda44f14caed0cbdf6da5660 229 SMART SM00382 32 223 5.0E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS07985 6f6d4b6afda44f14caed0cbdf6da5660 229 Pfam PF00005 ABC transporter 23 172 1.8E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS07985 6f6d4b6afda44f14caed0cbdf6da5660 229 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS12205 5660bd3c6ffc4d2625a044feabe58b0a 273 Gene3D G3DSA:3.40.50.1580 4 271 7.2E-114 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 GTHT12_RS12205 5660bd3c6ffc4d2625a044feabe58b0a 273 SUPERFAMILY SSF53167 4 271 7.86E-102 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 GTHT12_RS12205 5660bd3c6ffc4d2625a044feabe58b0a 273 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 23 268 3.0E-111 T 06-07-2017 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 GTHT12_RS12205 5660bd3c6ffc4d2625a044feabe58b0a 273 Pfam PF01048 Phosphorylase superfamily 23 269 2.4E-59 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 GTHT12_RS12205 5660bd3c6ffc4d2625a044feabe58b0a 273 PIRSF PIRSF000477 1 271 1.6E-118 T 06-07-2017 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 GTHT12_RS12205 5660bd3c6ffc4d2625a044feabe58b0a 273 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 23 269 1.6E-115 T 06-07-2017 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 GTHT12_RS12205 5660bd3c6ffc4d2625a044feabe58b0a 273 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 75 116 - T 06-07-2017 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 GTHT12_RS06530 5344bbe26eb5c191b2ff5dde866ee0a3 157 Pfam PF02576 Putative ribosome maturation factor RimP 12 152 4.9E-50 T 06-07-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 GTHT12_RS06530 5344bbe26eb5c191b2ff5dde866ee0a3 157 Gene3D G3DSA:3.30.300.70 2 81 1.6E-31 T 06-07-2017 IPR028989 Ribosome maturation factor RimP, N-terminal GTHT12_RS06530 5344bbe26eb5c191b2ff5dde866ee0a3 157 SUPERFAMILY SSF75420 3 84 3.92E-28 T 06-07-2017 IPR028989 Ribosome maturation factor RimP, N-terminal GTHT12_RS06530 5344bbe26eb5c191b2ff5dde866ee0a3 157 Gene3D G3DSA:2.30.30.180 88 154 9.6E-29 T 06-07-2017 IPR028998 Ribosome maturation factor RimP, C-terminal GTHT12_RS06530 5344bbe26eb5c191b2ff5dde866ee0a3 157 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 156 25.016 T 06-07-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 GTHT12_RS06530 5344bbe26eb5c191b2ff5dde866ee0a3 157 SUPERFAMILY SSF74942 85 156 2.09E-20 T 06-07-2017 IPR028998 Ribosome maturation factor RimP, C-terminal GTHT12_RS06205 e9f6aef052c72cbc74445b260be10451 329 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 46 322 2.8E-119 T 06-07-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 GTHT12_RS06205 e9f6aef052c72cbc74445b260be10451 329 Pfam PF00448 SRP54-type protein, GTPase domain 123 322 5.6E-83 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GTHT12_RS06205 e9f6aef052c72cbc74445b260be10451 329 SMART SM00382 121 299 1.8E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS06205 e9f6aef052c72cbc74445b260be10451 329 SMART SM00963 22 103 1.6E-24 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GTHT12_RS06205 e9f6aef052c72cbc74445b260be10451 329 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 46 323 65.561 T 06-07-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 GTHT12_RS06205 e9f6aef052c72cbc74445b260be10451 329 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 296 309 - T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GTHT12_RS06205 e9f6aef052c72cbc74445b260be10451 329 SUPERFAMILY SSF47364 19 97 3.93E-21 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GTHT12_RS06205 e9f6aef052c72cbc74445b260be10451 329 SUPERFAMILY SSF52540 123 321 4.96E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06205 e9f6aef052c72cbc74445b260be10451 329 Gene3D G3DSA:1.20.120.140 47 132 3.5E-26 T 06-07-2017 GTHT12_RS06205 e9f6aef052c72cbc74445b260be10451 329 SMART SM00962 122 323 2.9E-125 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GTHT12_RS06205 e9f6aef052c72cbc74445b260be10451 329 Gene3D G3DSA:3.40.50.300 133 322 1.0E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06205 e9f6aef052c72cbc74445b260be10451 329 Pfam PF02881 SRP54-type protein, helical bundle domain 33 99 7.1E-14 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GTHT12_RS13185 305c0b6784fa514698ffa9fbe6e955e5 155 TIGRFAM TIGR02571 ComEB: ComE operon protein 2 2 148 1.5E-86 T 06-07-2017 IPR013404 Competence operon E, ComEB GTHT12_RS13185 305c0b6784fa514698ffa9fbe6e955e5 155 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 70 106 - T 06-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 GTHT12_RS13185 305c0b6784fa514698ffa9fbe6e955e5 155 SUPERFAMILY SSF53927 7 140 6.96E-42 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 GTHT12_RS13185 305c0b6784fa514698ffa9fbe6e955e5 155 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 116 8.0E-31 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 GTHT12_RS13185 305c0b6784fa514698ffa9fbe6e955e5 155 PIRSF PIRSF006019 1 148 5.0E-60 T 06-07-2017 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-500753 GTHT12_RS13185 305c0b6784fa514698ffa9fbe6e955e5 155 Gene3D G3DSA:3.40.140.10 5 143 2.2E-44 T 06-07-2017 GTHT12_RS15890 e5d1742f2964529d1a0754d2e5b2fd5f 253 SUPERFAMILY SSF51351 1 249 1.44E-94 T 06-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15890 e5d1742f2964529d1a0754d2e5b2fd5f 253 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 06-07-2017 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15890 e5d1742f2964529d1a0754d2e5b2fd5f 253 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 2.9E-57 T 06-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15890 e5d1742f2964529d1a0754d2e5b2fd5f 253 Pfam PF00121 Triosephosphate isomerase 5 247 2.0E-92 T 06-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15890 e5d1742f2964529d1a0754d2e5b2fd5f 253 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 250 40.939 T 06-07-2017 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15890 e5d1742f2964529d1a0754d2e5b2fd5f 253 Gene3D G3DSA:3.20.20.70 1 249 6.7E-105 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS11635 bb1dd5d030fa0386e00aa7fbc943ab68 404 SUPERFAMILY SSF53686 5 389 5.37E-148 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GTHT12_RS11635 bb1dd5d030fa0386e00aa7fbc943ab68 404 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 83 97 - T 06-07-2017 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 GTHT12_RS11635 bb1dd5d030fa0386e00aa7fbc943ab68 404 PIRSF PIRSF001413 1 398 9.7E-167 T 06-07-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 GTHT12_RS11635 bb1dd5d030fa0386e00aa7fbc943ab68 404 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 9 390 2.4E-188 T 06-07-2017 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 GTHT12_RS11635 bb1dd5d030fa0386e00aa7fbc943ab68 404 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 4 392 52.863 T 06-07-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 GTHT12_RS11635 bb1dd5d030fa0386e00aa7fbc943ab68 404 Gene3D G3DSA:3.40.50.1100 100 179 7.2E-21 T 06-07-2017 GTHT12_RS11635 bb1dd5d030fa0386e00aa7fbc943ab68 404 Gene3D G3DSA:3.40.50.1100 180 393 1.2E-93 T 06-07-2017 GTHT12_RS11635 bb1dd5d030fa0386e00aa7fbc943ab68 404 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 56 379 2.3E-51 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GTHT12_RS10205 4b2e1d69b47394a4f0060acbf47f202d 274 SUPERFAMILY SSF161098 6 273 6.73E-73 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS10205 4b2e1d69b47394a4f0060acbf47f202d 274 Gene3D G3DSA:1.10.3720.10 8 262 1.4E-68 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS10205 4b2e1d69b47394a4f0060acbf47f202d 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 266 7.9E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS07375 c4139b8886fbc24a922d9c3fb2562b6c 463 Pfam PF00324 Amino acid permease 14 448 4.2E-124 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 GTHT12_RS07375 c4139b8886fbc24a922d9c3fb2562b6c 463 TIGRFAM TIGR01773 GABAperm: GABA permease 6 447 1.6E-213 T 06-07-2017 IPR011265 GABA permease GO:0015185|GO:0015812|GO:0016021 GTHT12_RS07375 c4139b8886fbc24a922d9c3fb2562b6c 463 ProSitePatterns PS00218 Amino acid permeases signature. 39 69 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 GTHT12_RS07375 c4139b8886fbc24a922d9c3fb2562b6c 463 PIRSF PIRSF006060 1 462 6.2E-77 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 GTHT12_RS06295 cdd4ad746d94c99f5d4b19e9d555ce83 300 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 6 300 57.752 T 06-07-2017 IPR023009 Tyrosine recombinase XerC/XerD GTHT12_RS06295 cdd4ad746d94c99f5d4b19e9d555ce83 300 SUPERFAMILY SSF56349 9 294 2.65E-59 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 GTHT12_RS06295 cdd4ad746d94c99f5d4b19e9d555ce83 300 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 8 91 4.2E-24 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 GTHT12_RS06295 cdd4ad746d94c99f5d4b19e9d555ce83 300 Pfam PF00589 Phage integrase family 113 286 1.5E-48 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS06295 cdd4ad746d94c99f5d4b19e9d555ce83 300 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 10 300 4.5E-109 T 06-07-2017 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 GTHT12_RS06295 cdd4ad746d94c99f5d4b19e9d555ce83 300 Gene3D G3DSA:1.10.150.130 8 99 6.0E-30 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal GTHT12_RS06295 cdd4ad746d94c99f5d4b19e9d555ce83 300 Gene3D G3DSA:1.10.443.10 113 293 1.9E-58 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS14735 4e3af1a45a9b629cb45c78ef9d68d4dd 104 SUPERFAMILY SSF52821 3 98 8.25E-31 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS14735 4e3af1a45a9b629cb45c78ef9d68d4dd 104 Pfam PF00581 Rhodanese-like domain 8 97 1.9E-15 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS14735 4e3af1a45a9b629cb45c78ef9d68d4dd 104 Gene3D G3DSA:3.40.250.10 1 99 1.8E-29 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS14735 4e3af1a45a9b629cb45c78ef9d68d4dd 104 SMART SM00450 8 102 7.9E-20 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS15515 ce6b7a155c3e8fdcdc0a35c57b6e4fb4 298 SMART SM00729 57 265 1.1E-15 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 GTHT12_RS15515 ce6b7a155c3e8fdcdc0a35c57b6e4fb4 298 PIRSF PIRSF005963 1 298 1.8E-138 T 06-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 GTHT12_RS15515 ce6b7a155c3e8fdcdc0a35c57b6e4fb4 298 Hamap MF_00206 Lipoyl synthase [lipA]. 1 295 150.231 T 06-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 GTHT12_RS15515 ce6b7a155c3e8fdcdc0a35c57b6e4fb4 298 TIGRFAM TIGR00510 lipA: lipoyl synthase 3 291 2.2E-122 T 06-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 GTHT12_RS15515 ce6b7a155c3e8fdcdc0a35c57b6e4fb4 298 SUPERFAMILY SSF102114 21 289 5.36E-66 T 06-07-2017 GTHT12_RS15515 ce6b7a155c3e8fdcdc0a35c57b6e4fb4 298 Pfam PF04055 Radical SAM superfamily 64 223 6.2E-16 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 GTHT12_RS15515 ce6b7a155c3e8fdcdc0a35c57b6e4fb4 298 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 3 45 2.6E-9 T 06-07-2017 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 GTHT12_RS15515 ce6b7a155c3e8fdcdc0a35c57b6e4fb4 298 Gene3D G3DSA:3.20.20.70 27 292 8.3E-70 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS11665 3044631006db6befeb7ff607bf23df9c 366 Gene3D G3DSA:3.40.50.1970 4 174 2.2E-62 T 06-07-2017 GTHT12_RS11665 3044631006db6befeb7ff607bf23df9c 366 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 37 352 3.6E-116 T 06-07-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 GTHT12_RS11665 3044631006db6befeb7ff607bf23df9c 366 SUPERFAMILY SSF56796 4 357 1.44E-105 T 06-07-2017 GTHT12_RS11665 3044631006db6befeb7ff607bf23df9c 366 PIRSF PIRSF001455 7 362 1.3E-103 T 06-07-2017 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 GTHT12_RS11665 3044631006db6befeb7ff607bf23df9c 366 Pfam PF01761 3-dehydroquinate synthase 70 326 1.6E-99 T 06-07-2017 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 GTHT12_RS11665 3044631006db6befeb7ff607bf23df9c 366 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 359 40.153 T 06-07-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 GTHT12_RS11665 3044631006db6befeb7ff607bf23df9c 366 Gene3D G3DSA:1.20.1090.10 175 356 4.3E-56 T 06-07-2017 GTHT12_RS13470 d741841756321e8d42e4d892d3750d29 187 Pfam PF00578 AhpC/TSA family 4 133 1.7E-34 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GTHT12_RS13470 d741841756321e8d42e4d892d3750d29 187 SUPERFAMILY SSF52833 1 186 9.06E-57 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS13470 d741841756321e8d42e4d892d3750d29 187 PIRSF PIRSF000239 1 187 1.5E-52 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GTHT12_RS13470 d741841756321e8d42e4d892d3750d29 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 182 1.2E-5 T 06-07-2017 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GTHT12_RS13470 d741841756321e8d42e4d892d3750d29 187 Gene3D G3DSA:3.40.30.10 3 184 1.6E-63 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS13470 d741841756321e8d42e4d892d3750d29 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 8.4E-105 T 06-07-2017 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 GTHT12_RS07095 0630a3b805a7efc2485aeae29b9aeef8 131 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 125 1.2E-48 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 GTHT12_RS07095 0630a3b805a7efc2485aeae29b9aeef8 131 SUPERFAMILY SSF81330 10 121 1.57E-36 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 GTHT12_RS07095 0630a3b805a7efc2485aeae29b9aeef8 131 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 128 29.964 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 GTHT12_RS07095 0630a3b805a7efc2485aeae29b9aeef8 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 1.6E-13 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 GTHT12_RS07095 0630a3b805a7efc2485aeae29b9aeef8 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 93 1.6E-13 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 GTHT12_RS07095 0630a3b805a7efc2485aeae29b9aeef8 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 75 83 1.6E-13 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 GTHT12_RS07095 0630a3b805a7efc2485aeae29b9aeef8 131 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 127 1.7E-53 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 GTHT12_RS07095 0630a3b805a7efc2485aeae29b9aeef8 131 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 06-07-2017 IPR019823 Large-conductance mechanosensitive channel, conserved site GTHT12_RS09620 1678414ab1ef8a5884d71edbb43f3743 249 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 39.875 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 GTHT12_RS09620 1678414ab1ef8a5884d71edbb43f3743 249 Pfam PF00557 Metallopeptidase family M24 12 239 3.3E-55 T 06-07-2017 IPR000994 Peptidase M24, structural domain GTHT12_RS09620 1678414ab1ef8a5884d71edbb43f3743 249 SUPERFAMILY SSF55920 1 246 4.45E-86 T 06-07-2017 IPR000994 Peptidase M24, structural domain GTHT12_RS09620 1678414ab1ef8a5884d71edbb43f3743 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 3.1E-18 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase GTHT12_RS09620 1678414ab1ef8a5884d71edbb43f3743 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 3.1E-18 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase GTHT12_RS09620 1678414ab1ef8a5884d71edbb43f3743 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 3.1E-18 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase GTHT12_RS09620 1678414ab1ef8a5884d71edbb43f3743 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 3.1E-18 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase GTHT12_RS09620 1678414ab1ef8a5884d71edbb43f3743 249 Gene3D G3DSA:3.90.230.10 1 247 2.0E-90 T 06-07-2017 IPR000994 Peptidase M24, structural domain GTHT12_RS09620 1678414ab1ef8a5884d71edbb43f3743 249 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 GTHT12_RS09620 1678414ab1ef8a5884d71edbb43f3743 249 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 1.2E-93 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 GTHT12_RS11790 5d62a0c4e22b8cd77a34ad8d0fb298f2 195 Gene3D G3DSA:3.40.1130.10 3 192 1.1E-30 T 06-07-2017 GTHT12_RS11790 5d62a0c4e22b8cd77a34ad8d0fb298f2 195 SUPERFAMILY SSF69593 13 194 5.89E-53 T 06-07-2017 GTHT12_RS11790 5d62a0c4e22b8cd77a34ad8d0fb298f2 195 SMART SM00563 37 149 2.0E-37 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 GTHT12_RS11790 5d62a0c4e22b8cd77a34ad8d0fb298f2 195 Pfam PF01553 Acyltransferase 22 146 1.8E-25 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 GTHT12_RS13855 e1157782ade83681531a1bc55ae3baae 327 SUPERFAMILY SSF116965 82 277 8.5E-12 T 06-07-2017 GTHT12_RS13855 e1157782ade83681531a1bc55ae3baae 327 SUPERFAMILY SSF48452 11 110 4.88E-15 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS13855 e1157782ade83681531a1bc55ae3baae 327 Pfam PF14559 Tetratricopeptide repeat 26 83 1.1E-10 T 06-07-2017 GTHT12_RS13855 e1157782ade83681531a1bc55ae3baae 327 Gene3D G3DSA:1.25.40.10 66 113 1.3E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS13855 e1157782ade83681531a1bc55ae3baae 327 Gene3D G3DSA:1.25.40.10 13 65 2.5E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS04245 8eee12a663a4c05c292d8f14ae3348ab 190 SUPERFAMILY SSF48498 82 188 2.57E-8 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal GTHT12_RS04245 8eee12a663a4c05c292d8f14ae3348ab 190 Gene3D G3DSA:1.10.357.10 12 189 5.6E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 GTHT12_RS04245 8eee12a663a4c05c292d8f14ae3348ab 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 8.6E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS04245 8eee12a663a4c05c292d8f14ae3348ab 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 8.6E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS04245 8eee12a663a4c05c292d8f14ae3348ab 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 55 3.8E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS04245 8eee12a663a4c05c292d8f14ae3348ab 190 SUPERFAMILY SSF46689 4 66 1.25E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS09045 ae54034348ba784ffb17ce6c2ce035a3 522 Pfam PF05598 Transposase domain (DUF772) 49 117 1.6E-22 T 06-07-2017 IPR008490 Transposase InsH, N-terminal GTHT12_RS09045 ae54034348ba784ffb17ce6c2ce035a3 522 Pfam PF13751 Transposase DDE domain 382 506 1.7E-30 T 06-07-2017 IPR025668 Transposase DDE domain GTHT12_RS17125 ae54034348ba784ffb17ce6c2ce035a3 522 Pfam PF05598 Transposase domain (DUF772) 49 117 1.6E-22 T 06-07-2017 IPR008490 Transposase InsH, N-terminal GTHT12_RS17125 ae54034348ba784ffb17ce6c2ce035a3 522 Pfam PF13751 Transposase DDE domain 382 506 1.7E-30 T 06-07-2017 IPR025668 Transposase DDE domain GTHT12_RS05550 ae54034348ba784ffb17ce6c2ce035a3 522 Pfam PF05598 Transposase domain (DUF772) 49 117 1.6E-22 T 06-07-2017 IPR008490 Transposase InsH, N-terminal GTHT12_RS05550 ae54034348ba784ffb17ce6c2ce035a3 522 Pfam PF13751 Transposase DDE domain 382 506 1.7E-30 T 06-07-2017 IPR025668 Transposase DDE domain GTHT12_RS15800 6f0c85618670fb6d5f0a04029c6ae3a2 245 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 47 244 6.3E-64 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GTHT12_RS15800 6f0c85618670fb6d5f0a04029c6ae3a2 245 TIGRFAM TIGR02303 HpaG-C-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit 2 244 2.2E-112 T 06-07-2017 IPR012684 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit GO:0008704|GO:0018800|GO:1901023 KEGG: 00350+5.3.3.10+4.1.1.68 GTHT12_RS15800 6f0c85618670fb6d5f0a04029c6ae3a2 245 Gene3D G3DSA:3.90.850.10 37 244 6.3E-80 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GTHT12_RS15800 6f0c85618670fb6d5f0a04029c6ae3a2 245 SUPERFAMILY SSF56529 37 244 1.57E-74 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GTHT12_RS15270 c0c8b0d320fc36b124db634264f8441d 331 Gene3D G3DSA:1.10.287.70 13 96 3.9E-22 T 06-07-2017 GTHT12_RS15270 c0c8b0d320fc36b124db634264f8441d 331 Gene3D G3DSA:3.40.50.720 109 238 5.1E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS15270 c0c8b0d320fc36b124db634264f8441d 331 Pfam PF07885 Ion channel 26 95 1.0E-14 T 06-07-2017 IPR013099 Potassium channel domain GTHT12_RS15270 c0c8b0d320fc36b124db634264f8441d 331 SUPERFAMILY SSF81324 6 129 4.71E-24 T 06-07-2017 GTHT12_RS15270 c0c8b0d320fc36b124db634264f8441d 331 Pfam PF02254 TrkA-N domain 117 239 5.4E-16 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 GTHT12_RS15270 c0c8b0d320fc36b124db634264f8441d 331 SUPERFAMILY SSF51735 114 261 1.48E-19 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS05675 d5babde3786b12b64d2aced61869ebf2 403 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 338 362 - T 06-07-2017 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 GTHT12_RS05675 d5babde3786b12b64d2aced61869ebf2 403 Pfam PF01098 Cell cycle protein 18 381 1.6E-106 T 06-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 GTHT12_RS09320 c0db41955b94488873e13dc360fbe3ba 423 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 27 317 7.7E-78 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GTHT12_RS09320 c0db41955b94488873e13dc360fbe3ba 423 TIGRFAM TIGR02079 THD1: threonine dehydratase 16 423 5.3E-198 T 06-07-2017 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 GTHT12_RS09320 c0db41955b94488873e13dc360fbe3ba 423 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 330 422 8.3E-29 T 06-07-2017 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 GTHT12_RS09320 c0db41955b94488873e13dc360fbe3ba 423 SUPERFAMILY SSF55021 340 417 2.01E-11 T 06-07-2017 GTHT12_RS09320 c0db41955b94488873e13dc360fbe3ba 423 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 52 65 - T 06-07-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 GTHT12_RS09320 c0db41955b94488873e13dc360fbe3ba 423 Gene3D G3DSA:3.40.50.1100 106 348 4.3E-89 T 06-07-2017 GTHT12_RS09320 c0db41955b94488873e13dc360fbe3ba 423 SUPERFAMILY SSF53686 13 366 7.2E-103 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GTHT12_RS01450 2a8436c5fcdc161419ca1c039d4e2c55 162 SUPERFAMILY SSF55040 11 157 1.57E-57 T 06-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 GTHT12_RS01450 2a8436c5fcdc161419ca1c039d4e2c55 162 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 2 160 36.147 T 06-07-2017 IPR023046 Molybdenum cofactor biosynthesis C, bacterial-type Reactome: R-HSA-947581 GTHT12_RS01450 2a8436c5fcdc161419ca1c039d4e2c55 162 Gene3D G3DSA:3.30.70.640 3 160 2.6E-66 T 06-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 GTHT12_RS01450 2a8436c5fcdc161419ca1c039d4e2c55 162 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 154 3.4E-64 T 06-07-2017 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 GTHT12_RS01450 2a8436c5fcdc161419ca1c039d4e2c55 162 Pfam PF01967 MoaC family 15 152 2.4E-52 T 06-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 GTHT12_RS00220 8f571042c0598e21e6932e32818c0d40 187 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 2 176 1.3E-58 T 06-07-2017 IPR004466 Ribonuclease M5 GO:0043822 GTHT12_RS00220 8f571042c0598e21e6932e32818c0d40 187 Pfam PF13662 Toprim domain 4 71 5.2E-8 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS00220 8f571042c0598e21e6932e32818c0d40 187 Hamap MF_01469 Ribonuclease M5 [rnmV]. 2 178 31.412 T 06-07-2017 IPR004466 Ribonuclease M5 GO:0043822 GTHT12_RS00220 8f571042c0598e21e6932e32818c0d40 187 Pfam PF13331 Domain of unknown function (DUF4093) 93 176 1.3E-26 T 06-07-2017 IPR025156 Ribonuclease M5, C-terminal domain GTHT12_RS00220 8f571042c0598e21e6932e32818c0d40 187 SMART SM00493 4 77 9.6E-11 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS00220 8f571042c0598e21e6932e32818c0d40 187 Gene3D G3DSA:3.40.1360.20 1 122 1.3E-41 T 06-07-2017 GTHT12_RS00220 8f571042c0598e21e6932e32818c0d40 187 SUPERFAMILY SSF110455 1 115 7.32E-36 T 06-07-2017 GTHT12_RS08330 a769ac98799d9285d6e14c6c3b8086b7 135 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 2.2E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS08330 a769ac98799d9285d6e14c6c3b8086b7 135 SUPERFAMILY SSF46785 5 79 3.06E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS08330 a769ac98799d9285d6e14c6c3b8086b7 135 Gene3D G3DSA:1.10.10.10 2 76 1.6E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS08330 a769ac98799d9285d6e14c6c3b8086b7 135 SMART SM00345 16 75 2.1E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS15605 7ea114968830107324e2058f77f0e969 120 Gene3D G3DSA:1.20.1290.10 17 110 1.7E-33 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 GTHT12_RS15605 7ea114968830107324e2058f77f0e969 120 Pfam PF02627 Carboxymuconolactone decarboxylase family 28 109 2.2E-19 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 GTHT12_RS15605 7ea114968830107324e2058f77f0e969 120 SUPERFAMILY SSF69118 14 116 7.07E-27 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 GTHT12_RS15605 7ea114968830107324e2058f77f0e969 120 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 45 95 7.7E-10 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 GTHT12_RS15900 4cb606b8a1c45a7fa40c5d80ee5c3ad8 335 Gene3D G3DSA:3.30.360.10 161 315 1.9E-82 T 06-07-2017 GTHT12_RS15900 4cb606b8a1c45a7fa40c5d80ee5c3ad8 335 SMART SM00846 3 152 3.4E-101 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15900 4cb606b8a1c45a7fa40c5d80ee5c3ad8 335 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 06-07-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15900 4cb606b8a1c45a7fa40c5d80ee5c3ad8 335 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 5.9E-74 T 06-07-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15900 4cb606b8a1c45a7fa40c5d80ee5c3ad8 335 SUPERFAMILY SSF55347 152 314 3.87E-76 T 06-07-2017 GTHT12_RS15900 4cb606b8a1c45a7fa40c5d80ee5c3ad8 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 9.9E-44 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15900 4cb606b8a1c45a7fa40c5d80ee5c3ad8 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 9.9E-44 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15900 4cb606b8a1c45a7fa40c5d80ee5c3ad8 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 9.9E-44 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15900 4cb606b8a1c45a7fa40c5d80ee5c3ad8 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 9.9E-44 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15900 4cb606b8a1c45a7fa40c5d80ee5c3ad8 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 9.9E-44 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15900 4cb606b8a1c45a7fa40c5d80ee5c3ad8 335 SUPERFAMILY SSF51735 3 168 1.16E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS15900 4cb606b8a1c45a7fa40c5d80ee5c3ad8 335 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 6.4E-143 T 06-07-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15900 4cb606b8a1c45a7fa40c5d80ee5c3ad8 335 PIRSF PIRSF000149 1 334 8.4E-148 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15900 4cb606b8a1c45a7fa40c5d80ee5c3ad8 335 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 152 6.3E-65 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15900 4cb606b8a1c45a7fa40c5d80ee5c3ad8 335 Gene3D G3DSA:3.40.50.720 1 160 2.7E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS04630 2550f6ba00cd56b1dbe059fe4136835f 266 SMART SM00382 41 189 5.9E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS04630 2550f6ba00cd56b1dbe059fe4136835f 266 Gene3D G3DSA:3.40.50.300 31 164 5.7E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS04630 2550f6ba00cd56b1dbe059fe4136835f 266 Pfam PF13401 AAA domain 40 169 3.4E-22 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS04630 2550f6ba00cd56b1dbe059fe4136835f 266 SUPERFAMILY SSF52540 29 263 5.08E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11465 956dc9dadc7e2ada49e12379f4d9b5e7 201 Gene3D G3DSA:3.40.1350.10 31 198 8.0E-76 T 06-07-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 GTHT12_RS11465 956dc9dadc7e2ada49e12379f4d9b5e7 201 PIRSF PIRSF037785 23 201 2.2E-78 T 06-07-2017 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 GTHT12_RS11465 956dc9dadc7e2ada49e12379f4d9b5e7 201 SUPERFAMILY SSF52980 32 198 4.29E-69 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 GTHT12_RS11465 956dc9dadc7e2ada49e12379f4d9b5e7 201 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 201 100.064 T 06-07-2017 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 GTHT12_RS11465 956dc9dadc7e2ada49e12379f4d9b5e7 201 TIGRFAM TIGR00648 recU: recombination protein U 29 196 1.0E-76 T 06-07-2017 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 GTHT12_RS11465 956dc9dadc7e2ada49e12379f4d9b5e7 201 Pfam PF03838 Recombination protein U 30 194 1.5E-68 T 06-07-2017 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 GTHT12_RS07215 6b907ddafb0a7b6f05ea20feb975c104 324 Gene3D G3DSA:1.10.10.10 7 74 1.9E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS07215 6b907ddafb0a7b6f05ea20feb975c104 324 Pfam PF13280 WYL domain 146 319 4.3E-31 T 06-07-2017 IPR026881 WYL domain GTHT12_RS02820 ca6b0ad2a23227360dd597a1f759576a 40 Gene3D G3DSA:3.30.70.270 4 39 2.1E-7 T 06-07-2017 GTHT12_RS02820 ca6b0ad2a23227360dd597a1f759576a 40 Pfam PF00990 Diguanylate cyclase, GGDEF domain 2 39 1.2E-6 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS11210 ce3414e82bde61529f71836cf2e323fb 91 SMART SM00418 5 83 3.8E-30 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS11210 ce3414e82bde61529f71836cf2e323fb 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 7 22 2.3E-17 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS11210 ce3414e82bde61529f71836cf2e323fb 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 2.3E-17 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS11210 ce3414e82bde61529f71836cf2e323fb 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 54 2.3E-17 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS11210 ce3414e82bde61529f71836cf2e323fb 91 Pfam PF01022 Bacterial regulatory protein, arsR family 12 57 2.3E-17 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS11210 ce3414e82bde61529f71836cf2e323fb 91 SUPERFAMILY SSF46785 5 84 5.55E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS11210 ce3414e82bde61529f71836cf2e323fb 91 Gene3D G3DSA:1.10.10.10 4 87 7.6E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS15600 095e3587417c8b2a60b91b1822e7a464 259 SUPERFAMILY SSF52540 4 231 5.58E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS15600 095e3587417c8b2a60b91b1822e7a464 259 Pfam PF00005 ABC transporter 19 171 9.2E-22 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS15600 095e3587417c8b2a60b91b1822e7a464 259 Gene3D G3DSA:3.40.50.300 3 231 1.4E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS15600 095e3587417c8b2a60b91b1822e7a464 259 SMART SM00382 28 223 3.2E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS15600 095e3587417c8b2a60b91b1822e7a464 259 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 244 4.8E-114 T 06-07-2017 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 GTHT12_RS15600 095e3587417c8b2a60b91b1822e7a464 259 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS00130 e263f25a8e2ce9382a57357dff6ea2d2 87 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 12 83 3.3E-21 T 06-07-2017 IPR010001 SigmaK-factor processing regulatory BofA GTHT12_RS00130 e263f25a8e2ce9382a57357dff6ea2d2 87 TIGRFAM TIGR02862 spore_BofA: pro-sigmaK processing inhibitor BofA 5 86 2.2E-29 T 06-07-2017 IPR010001 SigmaK-factor processing regulatory BofA GTHT12_RS06025 4e10fbf2688e78f5d923a168d85f1334 239 SMART SM00934 4 229 4.6E-88 T 06-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 GTHT12_RS06025 4e10fbf2688e78f5d923a168d85f1334 239 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 4 228 3.3E-45 T 06-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 GTHT12_RS06025 4e10fbf2688e78f5d923a168d85f1334 239 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 2 234 39.594 T 06-07-2017 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 GTHT12_RS06025 4e10fbf2688e78f5d923a168d85f1334 239 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 56 69 - T 06-07-2017 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 GTHT12_RS06025 4e10fbf2688e78f5d923a168d85f1334 239 Gene3D G3DSA:3.20.20.70 2 233 4.8E-78 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS06025 4e10fbf2688e78f5d923a168d85f1334 239 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 6 230 9.7E-58 T 06-07-2017 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 GTHT12_RS06025 4e10fbf2688e78f5d923a168d85f1334 239 SUPERFAMILY SSF51366 3 233 4.44E-68 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 GTHT12_RS16780 98588573900bc8385b9bdf6f41b23e2a 926 SUPERFAMILY SSF52540 668 919 1.4E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16780 98588573900bc8385b9bdf6f41b23e2a 926 Pfam PF00271 Helicase conserved C-terminal domain 751 863 2.0E-18 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS16780 98588573900bc8385b9bdf6f41b23e2a 926 Gene3D G3DSA:3.40.50.300 746 897 1.0E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16780 98588573900bc8385b9bdf6f41b23e2a 926 Gene3D G3DSA:3.40.50.300 442 623 3.2E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16780 98588573900bc8385b9bdf6f41b23e2a 926 Pfam PF00176 SNF2 family N-terminal domain 470 735 3.7E-59 T 06-07-2017 IPR000330 SNF2-related, N-terminal domain GO:0005524 GTHT12_RS16780 98588573900bc8385b9bdf6f41b23e2a 926 SMART SM00490 780 863 1.1E-23 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS16780 98588573900bc8385b9bdf6f41b23e2a 926 SMART SM00487 447 637 9.3E-33 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain GTHT12_RS16780 98588573900bc8385b9bdf6f41b23e2a 926 SUPERFAMILY SSF52540 410 665 2.88E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16780 98588573900bc8385b9bdf6f41b23e2a 926 Pfam PF12419 SNF2 Helicase protein 270 398 7.2E-35 T 06-07-2017 IPR022138 Helicase SWF/SNF-related GTHT12_RS09130 d3dd1639459ce2caf731e831bbb1c5e3 499 SUPERFAMILY SSF53383 32 466 9.04E-78 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS09130 d3dd1639459ce2caf731e831bbb1c5e3 499 Gene3D G3DSA:3.90.1150.10 322 467 2.0E-28 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS09130 d3dd1639459ce2caf731e831bbb1c5e3 499 Pfam PF00266 Aminotransferase class-V 46 454 1.2E-45 T 06-07-2017 IPR000192 Aminotransferase class V domain GTHT12_RS09130 d3dd1639459ce2caf731e831bbb1c5e3 499 Gene3D G3DSA:3.40.640.10 59 321 9.7E-60 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS00605 877ee0be68a2aa31b70bd1132ec93432 166 SUPERFAMILY SSF160369 5 160 3.14E-58 T 06-07-2017 GTHT12_RS00605 877ee0be68a2aa31b70bd1132ec93432 166 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 06-07-2017 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00605 877ee0be68a2aa31b70bd1132ec93432 166 Pfam PF00466 Ribosomal protein L10 6 101 1.1E-30 T 06-07-2017 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 GTHT12_RS00605 877ee0be68a2aa31b70bd1132ec93432 166 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 26 143 0.001 T 06-07-2017 GTHT12_RS00605 877ee0be68a2aa31b70bd1132ec93432 166 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 161 29.776 T 06-07-2017 IPR022973 Ribosomal protein L10 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 488 506 5.9E-17 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 604 620 5.9E-17 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 632 648 5.9E-17 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 664 689 5.9E-17 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 SUPERFAMILY SSF81665 225 318 1.44E-136 T 06-07-2017 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 SUPERFAMILY SSF81665 682 881 1.44E-136 T 06-07-2017 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 SUPERFAMILY SSF81665 1 114 1.44E-136 T 06-07-2017 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 Pfam PF00689 Cation transporting ATPase, C-terminus 716 882 5.6E-52 T 06-07-2017 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 TIGRFAM TIGR01116 ATPase-IIA1_Ca: calcium-translocating P-type ATPase, SERCA-type 54 876 1.6E-212 T 06-07-2017 IPR005782 P-type ATPase, subfamily IIA, SERCA-type GO:0005388|GO:0006816|GO:0016021 Reactome: R-HSA-1912420|Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 SUPERFAMILY SSF81653 114 224 6.02E-33 T 06-07-2017 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 530 541 1.0E-40 T 06-07-2017 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 632 651 1.0E-40 T 06-07-2017 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 161 175 1.0E-40 T 06-07-2017 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 552 562 1.0E-40 T 06-07-2017 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 324 338 1.0E-40 T 06-07-2017 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 656 668 1.0E-40 T 06-07-2017 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 83 346 6.8E-45 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 605 722 1.8E-35 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 429 576 7.0E-20 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 Gene3D G3DSA:2.70.150.10 14 55 2.0E-46 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 Gene3D G3DSA:2.70.150.10 109 224 2.0E-46 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 SUPERFAMILY SSF56784 485 736 2.15E-66 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 SUPERFAMILY SSF56784 322 342 2.15E-66 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 326 332 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 Pfam PF00690 Cation transporter/ATPase, N-terminus 3 71 3.3E-18 T 06-07-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 Gene3D G3DSA:3.40.1110.10 314 537 5.8E-65 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 Gene3D G3DSA:1.20.1110.10 601 881 5.4E-127 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 Gene3D G3DSA:1.20.1110.10 56 108 5.4E-127 T 06-07-2017 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 Pfam PF00702 haloacid dehalogenase-like hydrolase 322 646 3.3E-24 T 06-07-2017 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 SUPERFAMILY SSF81660 332 534 2.05E-56 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 SMART SM00831 2 76 1.8E-24 T 06-07-2017 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 GTHT12_RS06055 370e7b676bec7b0394b21f8abca1ba85 890 Pfam PF00122 E1-E2 ATPase 81 315 7.3E-68 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 GTHT12_RS03935 89a298bb578abd62dc06f7bbdcad6b39 339 Pfam PF02779 Transketolase, pyrimidine binding domain 12 181 5.7E-50 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain GTHT12_RS03935 89a298bb578abd62dc06f7bbdcad6b39 339 Gene3D G3DSA:3.40.50.920 208 337 4.3E-46 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GTHT12_RS03935 89a298bb578abd62dc06f7bbdcad6b39 339 Pfam PF02780 Transketolase, C-terminal domain 207 329 2.2E-40 T 06-07-2017 IPR033248 Transketolase, C-terminal domain GTHT12_RS03935 89a298bb578abd62dc06f7bbdcad6b39 339 SMART SM00861 9 184 8.4E-66 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain GTHT12_RS03935 89a298bb578abd62dc06f7bbdcad6b39 339 SUPERFAMILY SSF52518 9 217 1.08E-70 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS03935 89a298bb578abd62dc06f7bbdcad6b39 339 SUPERFAMILY SSF52922 202 337 1.7E-42 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GTHT12_RS03935 89a298bb578abd62dc06f7bbdcad6b39 339 Gene3D G3DSA:3.40.50.970 9 207 1.3E-78 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS06655 801c2b6f48c1eb644e7d10211ab82f2c 364 Gene3D G3DSA:3.40.50.2300 171 244 1.3E-10 T 06-07-2017 GTHT12_RS06655 801c2b6f48c1eb644e7d10211ab82f2c 364 Gene3D G3DSA:3.40.50.2300 35 170 2.2E-56 T 06-07-2017 GTHT12_RS06655 801c2b6f48c1eb644e7d10211ab82f2c 364 Pfam PF02608 Basic membrane protein 40 352 5.5E-91 T 06-07-2017 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 GTHT12_RS06655 801c2b6f48c1eb644e7d10211ab82f2c 364 SUPERFAMILY SSF53822 52 263 6.42E-13 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS16915 969fb06b61623c09e764894af0976720 253 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 06-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 GTHT12_RS16915 969fb06b61623c09e764894af0976720 253 Gene3D G3DSA:1.10.10.10 2 55 4.6E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS16915 969fb06b61623c09e764894af0976720 253 Pfam PF00455 DeoR C terminal sensor domain 75 231 2.2E-49 T 06-07-2017 IPR014036 DeoR C-terminal sensor domain GTHT12_RS16915 969fb06b61623c09e764894af0976720 253 SUPERFAMILY SSF46785 5 79 1.4E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS16915 969fb06b61623c09e764894af0976720 253 SUPERFAMILY SSF100950 74 233 1.47E-33 T 06-07-2017 GTHT12_RS16915 969fb06b61623c09e764894af0976720 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 1.4E-17 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 GTHT12_RS16915 969fb06b61623c09e764894af0976720 253 SMART SM00420 6 58 1.4E-18 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 GTHT12_RS16915 969fb06b61623c09e764894af0976720 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 7.1E-10 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 GTHT12_RS16915 969fb06b61623c09e764894af0976720 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 7.1E-10 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 GTHT12_RS16915 969fb06b61623c09e764894af0976720 253 SMART SM01134 73 233 7.3E-65 T 06-07-2017 GTHT12_RS16915 969fb06b61623c09e764894af0976720 253 Gene3D G3DSA:3.40.50.1360 77 221 4.2E-18 T 06-07-2017 GTHT12_RS17065 49714976cf8cc42523ef9436ca6ed704 158 Gene3D G3DSA:3.30.70.1290 6 126 3.6E-14 T 06-07-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 GTHT12_RS17065 49714976cf8cc42523ef9436ca6ed704 158 Pfam PF01797 Transposase IS200 like 12 121 1.4E-13 T 06-07-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 GTHT12_RS17065 49714976cf8cc42523ef9436ca6ed704 158 SMART SM01321 9 123 2.1E-31 T 06-07-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 GTHT12_RS17065 49714976cf8cc42523ef9436ca6ed704 158 SUPERFAMILY SSF143422 1 128 3.01E-25 T 06-07-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 GTHT12_RS10325 27de5973008a97f5262d8f7d18414cd5 185 Gene3D G3DSA:2.160.10.10 2 184 5.1E-67 T 06-07-2017 GTHT12_RS10325 27de5973008a97f5262d8f7d18414cd5 185 SMART SM01266 5 59 2.2E-24 T 06-07-2017 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 GTHT12_RS10325 27de5973008a97f5262d8f7d18414cd5 185 SUPERFAMILY SSF51161 2 184 1.94E-58 T 06-07-2017 IPR011004 Trimeric LpxA-like GTHT12_RS10325 27de5973008a97f5262d8f7d18414cd5 185 Pfam PF12464 Maltose acetyltransferase 8 58 4.4E-19 T 06-07-2017 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 GTHT12_RS10325 27de5973008a97f5262d8f7d18414cd5 185 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 139 167 - T 06-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 GTHT12_RS10325 27de5973008a97f5262d8f7d18414cd5 185 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 130 165 8.2E-12 T 06-07-2017 IPR001451 Hexapeptide repeat GTHT12_RS10325 27de5973008a97f5262d8f7d18414cd5 185 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 95 106 0.14 T 06-07-2017 IPR001451 Hexapeptide repeat GTHT12_RS17540 f3d6efce8a4332c8a0c30dd8f41cc88a 429 Pfam PF00672 HAMP domain 51 119 7.9E-16 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS17540 f3d6efce8a4332c8a0c30dd8f41cc88a 429 Gene3D G3DSA:1.10.287.950 102 175 2.8E-4 T 06-07-2017 GTHT12_RS17540 f3d6efce8a4332c8a0c30dd8f41cc88a 429 Gene3D G3DSA:1.10.287.950 176 384 1.3E-44 T 06-07-2017 GTHT12_RS17540 f3d6efce8a4332c8a0c30dd8f41cc88a 429 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 230 424 1.5E-37 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 GTHT12_RS17540 f3d6efce8a4332c8a0c30dd8f41cc88a 429 SUPERFAMILY SSF58104 158 426 2.22E-57 T 06-07-2017 GTHT12_RS17540 f3d6efce8a4332c8a0c30dd8f41cc88a 429 SUPERFAMILY SSF58104 99 125 2.22E-57 T 06-07-2017 GTHT12_RS17540 f3d6efce8a4332c8a0c30dd8f41cc88a 429 SMART SM00283 152 427 6.6E-49 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 GTHT12_RS17540 f3d6efce8a4332c8a0c30dd8f41cc88a 429 SMART SM00304 70 123 4.5E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS09280 8fb86ad402c056942292a0271e433d77 143 Gene3D G3DSA:2.20.25.10 2 40 8.0E-12 T 06-07-2017 GTHT12_RS09280 8fb86ad402c056942292a0271e433d77 143 SUPERFAMILY SSF82784 3 134 2.09E-41 T 06-07-2017 IPR003718 OsmC/Ohr family GTHT12_RS09280 8fb86ad402c056942292a0271e433d77 143 Pfam PF02566 OsmC-like protein 35 131 6.0E-21 T 06-07-2017 IPR003718 OsmC/Ohr family GTHT12_RS09280 8fb86ad402c056942292a0271e433d77 143 Gene3D G3DSA:3.30.300.20 41 135 5.0E-37 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta GTHT12_RS14775 60202b8ff9c12ebb4206a35d6dedf38e 173 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 120 4.8E-6 T 06-07-2017 IPR001451 Hexapeptide repeat GTHT12_RS14775 60202b8ff9c12ebb4206a35d6dedf38e 173 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 44 2.6E-5 T 06-07-2017 IPR001451 Hexapeptide repeat GTHT12_RS14775 60202b8ff9c12ebb4206a35d6dedf38e 173 SUPERFAMILY SSF51161 2 168 5.24E-50 T 06-07-2017 IPR011004 Trimeric LpxA-like GTHT12_RS14775 60202b8ff9c12ebb4206a35d6dedf38e 173 Gene3D G3DSA:2.160.10.10 2 169 8.9E-50 T 06-07-2017 GTHT12_RS03515 8d6116a220c4d81da59b0dbe632485f1 255 Hamap MF_00443 Thiazole synthase [thiG]. 1 254 43.798 T 06-07-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 GTHT12_RS03515 8d6116a220c4d81da59b0dbe632485f1 255 Gene3D G3DSA:3.20.20.70 1 251 5.8E-62 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS03515 8d6116a220c4d81da59b0dbe632485f1 255 SUPERFAMILY SSF110399 1 240 6.54E-85 T 06-07-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 GTHT12_RS03515 8d6116a220c4d81da59b0dbe632485f1 255 Pfam PF05690 Thiazole biosynthesis protein ThiG 4 248 2.2E-111 T 06-07-2017 GTHT12_RS17595 f6e2ae48404c6692099f0fe20927fb96 320 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 320 3.0E-157 T 06-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 GTHT12_RS17595 f6e2ae48404c6692099f0fe20927fb96 320 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 309 2.2E-145 T 06-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 GTHT12_RS17595 f6e2ae48404c6692099f0fe20927fb96 320 SUPERFAMILY SSF56655 1 312 2.56E-113 T 06-07-2017 GTHT12_RS17595 f6e2ae48404c6692099f0fe20927fb96 320 PIRSF PIRSF004532 1 320 9.4E-151 T 06-07-2017 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 GTHT12_RS17595 f6e2ae48404c6692099f0fe20927fb96 320 Gene3D G3DSA:3.30.540.10 173 316 1.1E-45 T 06-07-2017 GTHT12_RS17595 f6e2ae48404c6692099f0fe20927fb96 320 Gene3D G3DSA:3.30.540.10 1 172 6.0E-67 T 06-07-2017 GTHT12_RS18220 5b669238bcfa9269de66e3f4fb3a9d03 629 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 4.6E-6 T 06-07-2017 GTHT12_RS18220 5b669238bcfa9269de66e3f4fb3a9d03 629 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 161 4.6E-6 T 06-07-2017 GTHT12_RS18220 5b669238bcfa9269de66e3f4fb3a9d03 629 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 06-07-2017 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 GTHT12_RS18220 5b669238bcfa9269de66e3f4fb3a9d03 629 Gene3D G3DSA:3.50.50.60 7 204 7.8E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS18220 5b669238bcfa9269de66e3f4fb3a9d03 629 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 06-07-2017 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 GTHT12_RS18220 5b669238bcfa9269de66e3f4fb3a9d03 629 SUPERFAMILY SSF51905 98 260 2.13E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS18220 5b669238bcfa9269de66e3f4fb3a9d03 629 SUPERFAMILY SSF51905 7 67 2.13E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS18220 5b669238bcfa9269de66e3f4fb3a9d03 629 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 623 43.027 T 06-07-2017 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 GTHT12_RS18220 5b669238bcfa9269de66e3f4fb3a9d03 629 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 620 1.1E-297 T 06-07-2017 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 GTHT12_RS18220 5b669238bcfa9269de66e3f4fb3a9d03 629 Pfam PF01134 Glucose inhibited division protein A 9 398 7.0E-173 T 06-07-2017 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 GTHT12_RS18220 5b669238bcfa9269de66e3f4fb3a9d03 629 SMART SM01228 545 616 3.1E-44 T 06-07-2017 GTHT12_RS18220 5b669238bcfa9269de66e3f4fb3a9d03 629 Pfam PF13932 GidA associated domain 401 615 8.1E-76 T 06-07-2017 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 GTHT12_RS14870 9497506d6b0ba9a78687dd94cd65b8b0 53 Pfam PF07561 Domain of Unknown Function (DUF1540) 5 47 2.4E-15 T 06-07-2017 IPR011437 Domain of unknown function DUF1540 GTHT12_RS16740 7c87dfbd0377fea818f7dfa78b7b6cc2 449 Gene3D G3DSA:3.40.630.40 274 449 4.0E-52 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 GTHT12_RS16740 7c87dfbd0377fea818f7dfa78b7b6cc2 449 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 277 445 7.2E-44 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 GTHT12_RS16740 7c87dfbd0377fea818f7dfa78b7b6cc2 449 PIRSF PIRSF037846 2 449 1.0E-152 T 06-07-2017 IPR017293 N-acetylmuramoyl-L-alanine amidase, YrvJ, predicted GTHT12_RS16740 7c87dfbd0377fea818f7dfa78b7b6cc2 449 SUPERFAMILY SSF53187 274 448 9.73E-48 T 06-07-2017 GTHT12_RS16740 7c87dfbd0377fea818f7dfa78b7b6cc2 449 SMART SM00287 164 227 1.2E-12 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS16740 7c87dfbd0377fea818f7dfa78b7b6cc2 449 SMART SM00287 97 158 4.6E-5 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS16740 7c87dfbd0377fea818f7dfa78b7b6cc2 449 SMART SM00287 33 96 5.2E-7 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS16740 7c87dfbd0377fea818f7dfa78b7b6cc2 449 SMART SM00646 336 445 4.1E-25 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 GTHT12_RS16740 7c87dfbd0377fea818f7dfa78b7b6cc2 449 Pfam PF08239 Bacterial SH3 domain 173 224 5.6E-15 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS16740 7c87dfbd0377fea818f7dfa78b7b6cc2 449 Pfam PF08239 Bacterial SH3 domain 42 91 3.4E-6 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS16740 7c87dfbd0377fea818f7dfa78b7b6cc2 449 Pfam PF08239 Bacterial SH3 domain 105 154 3.1E-11 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS17915 34ce814eb6205e786103fc537af4bc69 302 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 144 218 5.2E-5 T 06-07-2017 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17915 34ce814eb6205e786103fc537af4bc69 302 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 47 107 7.4E-9 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17915 34ce814eb6205e786103fc537af4bc69 302 SUPERFAMILY SSF49503 121 274 1.06E-45 T 06-07-2017 IPR008972 Cupredoxin GTHT12_RS17915 34ce814eb6205e786103fc537af4bc69 302 Gene3D G3DSA:2.60.40.420 120 248 9.6E-38 T 06-07-2017 IPR008972 Cupredoxin GTHT12_RS17915 34ce814eb6205e786103fc537af4bc69 302 Gene3D G3DSA:1.10.287.90 26 111 1.5E-31 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17915 34ce814eb6205e786103fc537af4bc69 302 TIGRFAM TIGR01432 QOXA: cytochrome aa3 quinol oxidase, subunit II 11 235 1.0E-88 T 06-07-2017 IPR006332 Quinol oxidase subunit II GO:0009486|GO:0016021|GO:0016682|GO:0055114 GTHT12_RS17915 34ce814eb6205e786103fc537af4bc69 302 SUPERFAMILY SSF81464 28 113 6.21E-21 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17915 34ce814eb6205e786103fc537af4bc69 302 PIRSF PIRSF000292 1 301 4.0E-101 T 06-07-2017 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 GTHT12_RS07805 8b77d16628c030fb6a0913b1e6441e07 96 Gene3D G3DSA:1.20.1260.10 10 69 6.8E-7 T 06-07-2017 IPR012347 Ferritin-related GTHT12_RS07805 8b77d16628c030fb6a0913b1e6441e07 96 Pfam PF07875 Coat F domain 12 74 7.3E-24 T 06-07-2017 IPR012851 Spore coat protein CotF-like GTHT12_RS16965 5728f69adfe8e17663b1b54503864751 777 SUPERFAMILY SSF53756 309 534 3.77E-7 T 06-07-2017 GTHT12_RS16965 5728f69adfe8e17663b1b54503864751 777 Pfam PF12996 DUF based on E. rectale Gene description (DUF3880) 312 375 2.1E-9 T 06-07-2017 IPR024542 Domain of unknown function DUF3880 GTHT12_RS16965 5728f69adfe8e17663b1b54503864751 777 Pfam PF00535 Glycosyl transferase family 2 551 674 2.5E-17 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 GTHT12_RS16965 5728f69adfe8e17663b1b54503864751 777 Pfam PF13524 Glycosyl transferases group 1 446 535 9.5E-16 T 06-07-2017 GTHT12_RS16965 5728f69adfe8e17663b1b54503864751 777 Gene3D G3DSA:3.90.550.10 547 760 2.0E-31 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS16965 5728f69adfe8e17663b1b54503864751 777 SUPERFAMILY SSF53448 545 755 5.63E-36 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS04930 25a26d069add5f1f582e5929b385a8ea 375 Gene3D G3DSA:3.30.390.10 2 130 3.6E-51 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS04930 25a26d069add5f1f582e5929b385a8ea 375 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 15 127 2.9E-16 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain GTHT12_RS04930 25a26d069add5f1f582e5929b385a8ea 375 SMART SM00922 145 237 8.6E-23 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal GTHT12_RS04930 25a26d069add5f1f582e5929b385a8ea 375 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 3 362 45.325 T 06-07-2017 IPR010197 o-succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS04930 25a26d069add5f1f582e5929b385a8ea 375 Gene3D G3DSA:3.20.20.120 131 363 2.3E-71 T 06-07-2017 IPR029065 Enolase C-terminal domain-like GTHT12_RS04930 25a26d069add5f1f582e5929b385a8ea 375 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 13 335 7.7E-119 T 06-07-2017 IPR010197 o-succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS04930 25a26d069add5f1f582e5929b385a8ea 375 SUPERFAMILY SSF51604 116 364 8.78E-71 T 06-07-2017 IPR029065 Enolase C-terminal domain-like GTHT12_RS04930 25a26d069add5f1f582e5929b385a8ea 375 Pfam PF13378 Enolase C-terminal domain-like 150 356 6.0E-47 T 06-07-2017 IPR029065 Enolase C-terminal domain-like GTHT12_RS04930 25a26d069add5f1f582e5929b385a8ea 375 SUPERFAMILY SSF54826 5 128 3.05E-34 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS00070 14e057081db389e4a2693820c8b6c3af 488 PIRSF PIRSF000130 1 488 1.6E-214 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 GTHT12_RS00070 14e057081db389e4a2693820c8b6c3af 488 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 298 310 - T 06-07-2017 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 GTHT12_RS00070 14e057081db389e4a2693820c8b6c3af 488 SMART SM00116 98 148 1.8E-7 T 06-07-2017 IPR000644 CBS domain GTHT12_RS00070 14e057081db389e4a2693820c8b6c3af 488 SMART SM00116 161 209 1.6E-9 T 06-07-2017 IPR000644 CBS domain GTHT12_RS00070 14e057081db389e4a2693820c8b6c3af 488 Gene3D G3DSA:3.20.20.70 5 486 7.1E-211 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS00070 14e057081db389e4a2693820c8b6c3af 488 SMART SM01240 9 474 0.0 T 06-07-2017 GTHT12_RS00070 14e057081db389e4a2693820c8b6c3af 488 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 456 1.1E-206 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 GTHT12_RS00070 14e057081db389e4a2693820c8b6c3af 488 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 487 87.504 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 GTHT12_RS00070 14e057081db389e4a2693820c8b6c3af 488 SUPERFAMILY SSF54631 66 208 8.59E-33 T 06-07-2017 GTHT12_RS00070 14e057081db389e4a2693820c8b6c3af 488 SUPERFAMILY SSF51412 5 92 3.79E-129 T 06-07-2017 GTHT12_RS00070 14e057081db389e4a2693820c8b6c3af 488 SUPERFAMILY SSF51412 220 478 3.79E-129 T 06-07-2017 GTHT12_RS00070 14e057081db389e4a2693820c8b6c3af 488 Pfam PF00571 CBS domain 97 144 6.8E-7 T 06-07-2017 IPR000644 CBS domain GTHT12_RS00070 14e057081db389e4a2693820c8b6c3af 488 Pfam PF00571 CBS domain 153 204 3.8E-9 T 06-07-2017 IPR000644 CBS domain GTHT12_RS00070 14e057081db389e4a2693820c8b6c3af 488 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 474 1.1E-169 T 06-07-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 GTHT12_RS14405 32b05267ae1b6d59a7841d4a96a74996 531 Gene3D G3DSA:2.30.38.10 344 418 4.3E-20 T 06-07-2017 GTHT12_RS14405 32b05267ae1b6d59a7841d4a96a74996 531 Pfam PF13193 AMP-binding enzyme C-terminal domain 434 513 7.3E-25 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain GTHT12_RS14405 32b05267ae1b6d59a7841d4a96a74996 531 Gene3D G3DSA:3.40.50.980 16 181 3.8E-37 T 06-07-2017 GTHT12_RS14405 32b05267ae1b6d59a7841d4a96a74996 531 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 06-07-2017 IPR020845 AMP-binding, conserved site GTHT12_RS14405 32b05267ae1b6d59a7841d4a96a74996 531 SUPERFAMILY SSF56801 12 525 1.14E-148 T 06-07-2017 GTHT12_RS14405 32b05267ae1b6d59a7841d4a96a74996 531 Gene3D G3DSA:3.40.50.980 182 343 3.6E-35 T 06-07-2017 GTHT12_RS14405 32b05267ae1b6d59a7841d4a96a74996 531 Pfam PF00501 AMP-binding enzyme 19 425 3.2E-83 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GTHT12_RS14405 32b05267ae1b6d59a7841d4a96a74996 531 Gene3D G3DSA:3.30.300.30 420 523 3.2E-32 T 06-07-2017 GTHT12_RS00945 5272d53426c3b37b5dd743bc825ef844 600 Gene3D G3DSA:3.40.50.10490 242 437 2.4E-69 T 06-07-2017 GTHT12_RS00945 5272d53426c3b37b5dd743bc825ef844 600 Pfam PF01380 SIS domain 461 582 1.7E-16 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 GTHT12_RS00945 5272d53426c3b37b5dd743bc825ef844 600 Pfam PF01380 SIS domain 289 413 2.8E-35 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 GTHT12_RS00945 5272d53426c3b37b5dd743bc825ef844 600 Gene3D G3DSA:3.40.50.10490 438 600 2.7E-50 T 06-07-2017 GTHT12_RS00945 5272d53426c3b37b5dd743bc825ef844 600 Pfam PF13522 Glutamine amidotransferase domain 62 191 1.1E-21 T 06-07-2017 GTHT12_RS00945 5272d53426c3b37b5dd743bc825ef844 600 SUPERFAMILY SSF56235 2 235 1.54E-68 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal GTHT12_RS00945 5272d53426c3b37b5dd743bc825ef844 600 Gene3D G3DSA:3.60.20.10 2 239 1.9E-75 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal GTHT12_RS00945 5272d53426c3b37b5dd743bc825ef844 600 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 600 39.479 T 06-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 GTHT12_RS00945 5272d53426c3b37b5dd743bc825ef844 600 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 600 3.9E-233 T 06-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 GTHT12_RS00945 5272d53426c3b37b5dd743bc825ef844 600 SUPERFAMILY SSF53697 244 600 1.11E-97 T 06-07-2017 GTHT12_RS00530 b93cd78ad296cfac6ade7881ec5239c5 364 SMART SM00670 164 271 7.8E-13 T 06-07-2017 IPR002716 PIN domain GTHT12_RS00530 b93cd78ad296cfac6ade7881ec5239c5 364 SUPERFAMILY SSF88723 166 292 1.1E-24 T 06-07-2017 IPR029060 PIN domain-like GTHT12_RS00530 b93cd78ad296cfac6ade7881ec5239c5 364 Gene3D G3DSA:3.40.50.1010 166 293 2.1E-32 T 06-07-2017 IPR029060 PIN domain-like GTHT12_RS00530 b93cd78ad296cfac6ade7881ec5239c5 364 Pfam PF01938 TRAM domain 295 348 1.6E-6 T 06-07-2017 IPR002792 TRAM domain GTHT12_RS03305 3ff555bbc5a88e3d86f003c354596ea3 631 SMART SM00763 21 371 3.1E-202 T 06-07-2017 IPR013153 PrkA AAA domain GTHT12_RS03305 3ff555bbc5a88e3d86f003c354596ea3 631 Pfam PF08298 PrkA AAA domain 22 369 1.1E-153 T 06-07-2017 IPR013153 PrkA AAA domain GTHT12_RS03305 3ff555bbc5a88e3d86f003c354596ea3 631 Pfam PF06798 PrkA serine protein kinase C-terminal domain 375 624 5.5E-96 T 06-07-2017 IPR010650 PrkA C-terminal domain GTHT12_RS03305 3ff555bbc5a88e3d86f003c354596ea3 631 SUPERFAMILY SSF52540 231 363 1.28E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03305 3ff555bbc5a88e3d86f003c354596ea3 631 SUPERFAMILY SSF52540 68 178 1.28E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03305 3ff555bbc5a88e3d86f003c354596ea3 631 SUPERFAMILY SSF52540 405 468 1.28E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03305 3ff555bbc5a88e3d86f003c354596ea3 631 PIRSF PIRSF000549 1 631 2.1E-268 T 06-07-2017 IPR016230 Serine-protein kinase, PrkA GO:0004672 GTHT12_RS03305 3ff555bbc5a88e3d86f003c354596ea3 631 Gene3D G3DSA:3.40.50.300 235 320 7.5E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03305 3ff555bbc5a88e3d86f003c354596ea3 631 Gene3D G3DSA:3.40.50.300 67 164 7.5E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS15590 3e247be1472cb237c8e1ccbc4abd2618 406 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 4 403 2.2E-192 T 06-07-2017 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 GTHT12_RS15590 3e247be1472cb237c8e1ccbc4abd2618 406 PIRSF PIRSF005572 20 405 7.6E-56 T 06-07-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 GTHT12_RS15590 3e247be1472cb237c8e1ccbc4abd2618 406 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 215 234 - T 06-07-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site GTHT12_RS15590 3e247be1472cb237c8e1ccbc4abd2618 406 Pfam PF00266 Aminotransferase class-V 23 391 2.1E-167 T 06-07-2017 IPR000192 Aminotransferase class V domain GTHT12_RS15590 3e247be1472cb237c8e1ccbc4abd2618 406 Gene3D G3DSA:3.40.640.10 36 282 3.2E-95 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS15590 3e247be1472cb237c8e1ccbc4abd2618 406 Gene3D G3DSA:3.90.1150.10 283 397 4.3E-33 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS15590 3e247be1472cb237c8e1ccbc4abd2618 406 SUPERFAMILY SSF53383 2 398 1.2E-140 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS04725 d0fe34c6ac362ee08c52b710ef74a754 495 PIRSF PIRSF026631 8 472 1.5E-60 T 06-07-2017 IPR014529 Uncharacterised conserved protein UCP026631 GTHT12_RS04725 d0fe34c6ac362ee08c52b710ef74a754 495 Pfam PF03703 Bacterial PH domain 236 318 7.7E-12 T 06-07-2017 IPR005182 Domain of unknown function DUF304 GTHT12_RS04725 d0fe34c6ac362ee08c52b710ef74a754 495 Pfam PF03703 Bacterial PH domain 64 138 9.9E-10 T 06-07-2017 IPR005182 Domain of unknown function DUF304 GTHT12_RS04725 d0fe34c6ac362ee08c52b710ef74a754 495 Pfam PF03703 Bacterial PH domain 382 440 3.0E-8 T 06-07-2017 IPR005182 Domain of unknown function DUF304 GTHT12_RS16945 7df7f82593d29bb1fae6b29d76934b92 531 Gene3D G3DSA:3.40.50.300 3 259 4.8E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16945 7df7f82593d29bb1fae6b29d76934b92 531 SMART SM00382 49 220 2.2E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS16945 7df7f82593d29bb1fae6b29d76934b92 531 Pfam PF00005 ABC transporter 40 171 4.7E-21 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS16945 7df7f82593d29bb1fae6b29d76934b92 531 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS16945 7df7f82593d29bb1fae6b29d76934b92 531 SUPERFAMILY SSF52540 35 237 5.95E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03825 83d535549252221c6e5939c63ba0f372 74 Pfam PF10803 Spore germination GerPB 1 52 2.0E-31 T 06-07-2017 IPR024255 Spore germination GerPB GTHT12_RS03825 83d535549252221c6e5939c63ba0f372 74 ProDom PD027559 GERMINATION SPORE GERPB PROBABLE PB SPORULATION PB-RELATED 1 46 6.0E-17 T 06-07-2017 IPR024255 Spore germination GerPB GTHT12_RS04140 e30bc11de514c04b3eef034d535fec2e 236 Gene3D G3DSA:1.10.10.10 143 235 7.6E-37 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS04140 e30bc11de514c04b3eef034d535fec2e 236 SUPERFAMILY SSF46785 145 233 3.08E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS04140 e30bc11de514c04b3eef034d535fec2e 236 SUPERFAMILY SSF51206 19 143 8.64E-29 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like GTHT12_RS04140 e30bc11de514c04b3eef034d535fec2e 236 Pfam PF13545 Crp-like helix-turn-helix domain 149 220 4.4E-18 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 GTHT12_RS04140 e30bc11de514c04b3eef034d535fec2e 236 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 173 189 8.7E-7 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 GTHT12_RS04140 e30bc11de514c04b3eef034d535fec2e 236 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 189 204 8.7E-7 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 GTHT12_RS04140 e30bc11de514c04b3eef034d535fec2e 236 SMART SM00419 167 215 1.3E-13 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 GTHT12_RS04140 e30bc11de514c04b3eef034d535fec2e 236 SMART SM00100 7 127 3.9E-12 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain GTHT12_RS04140 e30bc11de514c04b3eef034d535fec2e 236 Gene3D G3DSA:2.60.120.10 18 141 2.6E-29 T 06-07-2017 IPR014710 RmlC-like jelly roll fold GTHT12_RS04140 e30bc11de514c04b3eef034d535fec2e 236 Pfam PF00027 Cyclic nucleotide-binding domain 29 112 4.9E-16 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1147 12.714 T 06-07-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 Gene3D G3DSA:2.30.150.10 548 614 4.0E-29 T 06-07-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 Pfam PF04565 RNA polymerase Rpb2, domain 3 469 537 5.4E-31 T 06-07-2017 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 Pfam PF00562 RNA polymerase Rpb2, domain 6 676 1069 1.6E-166 T 06-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 Gene3D G3DSA:2.40.270.10 752 779 7.7E-80 T 06-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 Gene3D G3DSA:2.40.270.10 919 1047 7.7E-80 T 06-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 SUPERFAMILY SSF64484 367 1157 0.0 T 06-07-2017 GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 SUPERFAMILY SSF64484 13 288 0.0 T 06-07-2017 GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 290 1.3E-28 T 06-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 Pfam PF04561 RNA polymerase Rpb2, domain 2 374 410 1.2E-6 T 06-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 Gene3D G3DSA:2.40.50.150 786 918 5.9E-58 T 06-07-2017 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 Pfam PF10385 RNA polymerase beta subunit external 1 domain 547 614 9.9E-28 T 06-07-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 Pfam PF04560 RNA polymerase Rpb2, domain 7 1071 1146 2.6E-27 T 06-07-2017 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 Gene3D G3DSA:3.90.1100.10 617 671 4.2E-156 T 06-07-2017 GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 Gene3D G3DSA:3.90.1100.10 21 140 4.2E-156 T 06-07-2017 GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 Gene3D G3DSA:3.90.1100.10 401 547 4.2E-156 T 06-07-2017 GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 Pfam PF04563 RNA polymerase beta subunit 28 454 1.1E-30 T 06-07-2017 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 Gene3D G3DSA:3.90.1110.10 376 400 3.4E-73 T 06-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 Gene3D G3DSA:3.90.1110.10 142 295 3.4E-73 T 06-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 Gene3D G3DSA:2.40.50.100 673 751 4.1E-30 T 06-07-2017 GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 204 896 0.0 T 06-07-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS00620 147854297384cb8c83d19310010277da 1190 ProSitePatterns PS01166 RNA polymerases beta chain signature. 922 934 - T 06-07-2017 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS03810 cc6233122f6843a9d03214e9a21323b0 129 Pfam PF10970 Protein of unknown function (DUF2772) 4 121 5.2E-43 T 06-07-2017 IPR024496 Spore germination protein GerPE GTHT12_RS03810 cc6233122f6843a9d03214e9a21323b0 129 ProDom PD031981 GERMINATION SPORE GERPE PE PROBABLE SPORULATION 5 120 1.0E-37 T 06-07-2017 IPR024496 Spore germination protein GerPE GTHT12_RS06595 eef940323193b94fae1f51d16a4c08d0 80 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 2 76 3.5E-29 T 06-07-2017 IPR014238 Sporulation protein YlmC/YmxH GTHT12_RS06595 eef940323193b94fae1f51d16a4c08d0 80 SUPERFAMILY SSF50346 2 75 3.92E-13 T 06-07-2017 IPR011033 PRC-barrel-like GTHT12_RS06595 eef940323193b94fae1f51d16a4c08d0 80 Gene3D G3DSA:2.30.30.240 2 77 6.1E-18 T 06-07-2017 GTHT12_RS06595 eef940323193b94fae1f51d16a4c08d0 80 Pfam PF05239 PRC-barrel domain 2 79 1.9E-16 T 06-07-2017 IPR027275 PRC-barrel domain GTHT12_RS10945 f154b8883ea1fc6a0b80120baac0fa21 98 SMART SM00450 4 97 8.5E-20 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS10945 f154b8883ea1fc6a0b80120baac0fa21 98 Gene3D G3DSA:3.40.250.10 2 94 1.9E-29 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS10945 f154b8883ea1fc6a0b80120baac0fa21 98 Pfam PF00581 Rhodanese-like domain 5 94 6.9E-15 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS10945 f154b8883ea1fc6a0b80120baac0fa21 98 SUPERFAMILY SSF52821 1 94 1.7E-32 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS18150 7702bfc1a1b79c023d5b14c7bf828fd7 308 Pfam PF09991 Predicted membrane protein (DUF2232) 15 300 2.7E-73 T 06-07-2017 IPR018710 Protein of unknown function DUF2232 GTHT12_RS17780 21e8a8b14ffa70912249dcf2309d12e8 190 PIRSF PIRSF038931 2 190 3.4E-51 T 06-07-2017 IPR014099 Spore coat protein GerQ GTHT12_RS17780 21e8a8b14ffa70912249dcf2309d12e8 190 Pfam PF09671 Spore coat protein (Spore_GerQ) 94 169 2.0E-39 T 06-07-2017 IPR014099 Spore coat protein GerQ GTHT12_RS17780 21e8a8b14ffa70912249dcf2309d12e8 190 TIGRFAM TIGR02728 spore_gerQ: spore coat protein GerQ 92 173 2.6E-43 T 06-07-2017 IPR014099 Spore coat protein GerQ GTHT12_RS05420 0259f2c496119ff2736a53631a212420 260 SUPERFAMILY SSF51735 11 257 1.45E-85 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS05420 0259f2c496119ff2736a53631a212420 260 Gene3D G3DSA:3.40.50.720 7 257 5.1E-89 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS05420 0259f2c496119ff2736a53631a212420 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 1.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05420 0259f2c496119ff2736a53631a212420 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05420 0259f2c496119ff2736a53631a212420 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 1.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05420 0259f2c496119ff2736a53631a212420 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 256 2.7E-64 T 06-07-2017 GTHT12_RS05420 0259f2c496119ff2736a53631a212420 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.7E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05420 0259f2c496119ff2736a53631a212420 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 2.7E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05420 0259f2c496119ff2736a53631a212420 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 2.7E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05420 0259f2c496119ff2736a53631a212420 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.7E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05420 0259f2c496119ff2736a53631a212420 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 2.7E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05420 0259f2c496119ff2736a53631a212420 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 2.7E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05420 0259f2c496119ff2736a53631a212420 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GTHT12_RS13620 a7563023c0dc97dc4a8e801e5aac2df1 186 Pfam PF14682 Sporulation initiation phospho-transferase B, C-terminal 61 171 5.1E-31 T 06-07-2017 IPR016122 Sporulation initiation phosphotransferase B, C-terminal GTHT12_RS13620 a7563023c0dc97dc4a8e801e5aac2df1 186 SMART SM01317 59 173 3.4E-62 T 06-07-2017 IPR016122 Sporulation initiation phosphotransferase B, C-terminal GTHT12_RS13620 a7563023c0dc97dc4a8e801e5aac2df1 186 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 6 57 1.8E-18 T 06-07-2017 GTHT12_RS13620 a7563023c0dc97dc4a8e801e5aac2df1 186 Gene3D G3DSA:1.10.287.130 1 57 4.0E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS13620 a7563023c0dc97dc4a8e801e5aac2df1 186 SUPERFAMILY SSF55890 1 175 1.44E-49 T 06-07-2017 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 GTHT12_RS13620 a7563023c0dc97dc4a8e801e5aac2df1 186 Gene3D G3DSA:3.30.565.30 58 175 2.5E-38 T 06-07-2017 IPR016122 Sporulation initiation phosphotransferase B, C-terminal GTHT12_RS18650 1b19ded9968caf9717346a71187f95e6 73 Pfam PF07872 Protein of unknown function (DUF1659) 9 50 8.9E-6 T 06-07-2017 IPR012454 Protein of unknown function DUF1659 GTHT12_RS06750 d3c8885de29f8cdc6f64e2ff7edfc65c 523 Pfam PF00919 Uncharacterized protein family UPF0004 81 182 8.5E-29 T 06-07-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 GTHT12_RS06750 d3c8885de29f8cdc6f64e2ff7edfc65c 523 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 80 517 76.156 T 06-07-2017 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 GTHT12_RS06750 d3c8885de29f8cdc6f64e2ff7edfc65c 523 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 229 249 - T 06-07-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 GTHT12_RS06750 d3c8885de29f8cdc6f64e2ff7edfc65c 523 Pfam PF04055 Radical SAM superfamily 229 400 5.6E-37 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 GTHT12_RS06750 d3c8885de29f8cdc6f64e2ff7edfc65c 523 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 81 513 4.2E-166 T 06-07-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 GTHT12_RS06750 d3c8885de29f8cdc6f64e2ff7edfc65c 523 SMART SM00729 225 443 4.0E-69 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 GTHT12_RS06750 d3c8885de29f8cdc6f64e2ff7edfc65c 523 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 81 515 4.8E-210 T 06-07-2017 GTHT12_RS06750 d3c8885de29f8cdc6f64e2ff7edfc65c 523 Gene3D G3DSA:3.80.30.20 224 455 4.6E-87 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe GTHT12_RS06750 d3c8885de29f8cdc6f64e2ff7edfc65c 523 SUPERFAMILY SSF102114 212 447 3.14E-67 T 06-07-2017 GTHT12_RS06750 d3c8885de29f8cdc6f64e2ff7edfc65c 523 Pfam PF01938 TRAM domain 454 515 6.6E-14 T 06-07-2017 IPR002792 TRAM domain GTHT12_RS15525 0b42831ca48561061b3fa5934fffcf8f 235 Gene3D G3DSA:3.40.50.300 1 230 2.3E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS15525 0b42831ca48561061b3fa5934fffcf8f 235 Pfam PF00005 ABC transporter 17 162 1.4E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS15525 0b42831ca48561061b3fa5934fffcf8f 235 SMART SM00382 26 211 2.7E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS15525 0b42831ca48561061b3fa5934fffcf8f 235 SUPERFAMILY SSF52540 2 233 1.44E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS15525 0b42831ca48561061b3fa5934fffcf8f 235 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS15525 0b42831ca48561061b3fa5934fffcf8f 235 PIRSF PIRSF039137 1 235 1.1E-115 T 06-07-2017 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 GTHT12_RS12880 6e185b1b4fb9ad76837e92697f3f1803 217 Gene3D G3DSA:1.20.58.220 122 216 1.2E-23 T 06-07-2017 GTHT12_RS12880 6e185b1b4fb9ad76837e92697f3f1803 217 SUPERFAMILY SSF109755 2 216 9.31E-63 T 06-07-2017 GTHT12_RS12880 6e185b1b4fb9ad76837e92697f3f1803 217 PIRSF PIRSF003107 1 217 6.6E-61 T 06-07-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 GTHT12_RS12880 6e185b1b4fb9ad76837e92697f3f1803 217 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 212 1.0E-61 T 06-07-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 GTHT12_RS12880 6e185b1b4fb9ad76837e92697f3f1803 217 Gene3D G3DSA:1.20.58.220 1 107 2.3E-32 T 06-07-2017 GTHT12_RS12880 6e185b1b4fb9ad76837e92697f3f1803 217 Pfam PF01895 PhoU domain 122 203 2.3E-14 T 06-07-2017 IPR026022 PhoU domain GTHT12_RS12880 6e185b1b4fb9ad76837e92697f3f1803 217 Pfam PF01895 PhoU domain 16 102 4.3E-23 T 06-07-2017 IPR026022 PhoU domain GTHT12_RS03895 edb7b1338bb9e054958644b075a5d1e6 588 SMART SM00642 139 497 1.6E-139 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GTHT12_RS03895 edb7b1338bb9e054958644b075a5d1e6 588 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 1 121 1.4E-50 T 06-07-2017 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 GTHT12_RS03895 edb7b1338bb9e054958644b075a5d1e6 588 Gene3D G3DSA:3.20.20.80 129 499 1.2E-131 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS03895 edb7b1338bb9e054958644b075a5d1e6 588 Gene3D G3DSA:2.60.40.1180 506 585 4.0E-29 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta GTHT12_RS03895 edb7b1338bb9e054958644b075a5d1e6 588 SUPERFAMILY SSF51445 68 506 1.28E-138 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS03895 edb7b1338bb9e054958644b075a5d1e6 588 SUPERFAMILY SSF51011 506 586 1.02E-20 T 06-07-2017 GTHT12_RS03895 edb7b1338bb9e054958644b075a5d1e6 588 Pfam PF00128 Alpha amylase, catalytic domain 173 469 5.0E-94 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GTHT12_RS03895 edb7b1338bb9e054958644b075a5d1e6 588 Pfam PF16657 Maltogenic Amylase, C-terminal domain 506 581 2.2E-16 T 06-07-2017 IPR032091 Maltogenic Amylase, C-terminal GTHT12_RS03895 edb7b1338bb9e054958644b075a5d1e6 588 Gene3D G3DSA:2.60.40.10 1 124 3.7E-50 T 06-07-2017 IPR013783 Immunoglobulin-like fold GTHT12_RS09595 8897636a63adb6f3c6591b6f10649369 264 Gene3D G3DSA:3.40.50.10090 42 164 1.7E-38 T 06-07-2017 GTHT12_RS09595 8897636a63adb6f3c6591b6f10649369 264 Gene3D G3DSA:3.40.50.10090 171 255 3.2E-23 T 06-07-2017 GTHT12_RS09595 8897636a63adb6f3c6591b6f10649369 264 SUPERFAMILY SSF69618 3 263 2.22E-58 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS09595 8897636a63adb6f3c6591b6f10649369 264 Pfam PF02602 Uroporphyrinogen-III synthase HemD 15 255 9.1E-41 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS03350 19350c10b154fd2073d84ff9a8061ea9 275 Gene3D G3DSA:3.20.20.100 8 272 1.9E-112 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain GTHT12_RS03350 19350c10b154fd2073d84ff9a8061ea9 275 PRINTS PR00069 Aldo-keto reductase signature 39 63 3.6E-53 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GTHT12_RS03350 19350c10b154fd2073d84ff9a8061ea9 275 PRINTS PR00069 Aldo-keto reductase signature 196 220 3.6E-53 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GTHT12_RS03350 19350c10b154fd2073d84ff9a8061ea9 275 PRINTS PR00069 Aldo-keto reductase signature 159 188 3.6E-53 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GTHT12_RS03350 19350c10b154fd2073d84ff9a8061ea9 275 PRINTS PR00069 Aldo-keto reductase signature 125 142 3.6E-53 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GTHT12_RS03350 19350c10b154fd2073d84ff9a8061ea9 275 PRINTS PR00069 Aldo-keto reductase signature 95 113 3.6E-53 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GTHT12_RS03350 19350c10b154fd2073d84ff9a8061ea9 275 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 229 244 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 GTHT12_RS03350 19350c10b154fd2073d84ff9a8061ea9 275 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 43 60 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 GTHT12_RS03350 19350c10b154fd2073d84ff9a8061ea9 275 Pfam PF00248 Aldo/keto reductase family 28 261 3.0E-54 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain GTHT12_RS03350 19350c10b154fd2073d84ff9a8061ea9 275 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 GTHT12_RS03350 19350c10b154fd2073d84ff9a8061ea9 275 SUPERFAMILY SSF51430 7 268 4.85E-100 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain GTHT12_RS13225 a2f1bc51d955606bdc223f18b2b4444d 276 SUPERFAMILY SSF53223 4 101 3.45E-35 T 06-07-2017 GTHT12_RS13225 a2f1bc51d955606bdc223f18b2b4444d 276 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 7 89 7.5E-31 T 06-07-2017 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 GTHT12_RS13225 a2f1bc51d955606bdc223f18b2b4444d 276 SUPERFAMILY SSF51735 102 273 7.12E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS13225 a2f1bc51d955606bdc223f18b2b4444d 276 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 2 272 36.42 T 06-07-2017 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 GTHT12_RS13225 a2f1bc51d955606bdc223f18b2b4444d 276 Gene3D G3DSA:3.40.50.720 107 274 3.5E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS13225 a2f1bc51d955606bdc223f18b2b4444d 276 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 115 192 5.1E-13 T 06-07-2017 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase GTHT12_RS13225 a2f1bc51d955606bdc223f18b2b4444d 276 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 4 274 3.4E-90 T 06-07-2017 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 GTHT12_RS13225 a2f1bc51d955606bdc223f18b2b4444d 276 Gene3D G3DSA:3.40.192.10 3 106 5.8E-43 T 06-07-2017 GTHT12_RS14720 10059e1e147ab1676f0b2d925fff94bd 541 PIRSF PIRSF038958 1 537 9.1E-117 T 06-07-2017 IPR024923 Peptidoglycan biosynthesis protein, SpoVB type GTHT12_RS14720 10059e1e147ab1676f0b2d925fff94bd 541 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 371 519 2.3E-29 T 06-07-2017 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain GTHT12_RS14720 10059e1e147ab1676f0b2d925fff94bd 541 Pfam PF01943 Polysaccharide biosynthesis protein 6 319 1.4E-46 T 06-07-2017 IPR002797 Polysaccharide biosynthesis protein GO:0016020 GTHT12_RS05490 c87d763e63e1027705a19126db62d745 405 SMART SM00052 2 241 2.8E-22 T 06-07-2017 IPR001633 EAL domain GTHT12_RS05490 c87d763e63e1027705a19126db62d745 405 Pfam PF00563 EAL domain 9 236 3.3E-37 T 06-07-2017 IPR001633 EAL domain GTHT12_RS05490 c87d763e63e1027705a19126db62d745 405 SUPERFAMILY SSF103190 263 401 3.37E-43 T 06-07-2017 IPR029151 Periplasmic sensor domain-like GTHT12_RS05490 c87d763e63e1027705a19126db62d745 405 Gene3D G3DSA:3.30.450.20 291 404 8.2E-50 T 06-07-2017 GTHT12_RS05490 c87d763e63e1027705a19126db62d745 405 Gene3D G3DSA:3.20.20.450 11 243 6.6E-34 T 06-07-2017 IPR001633 EAL domain GTHT12_RS05490 c87d763e63e1027705a19126db62d745 405 SUPERFAMILY SSF141868 3 258 9.02E-47 T 06-07-2017 IPR001633 EAL domain GTHT12_RS05490 c87d763e63e1027705a19126db62d745 405 Pfam PF10388 EAL-domain associated signalling protein domain 240 404 2.8E-79 T 06-07-2017 IPR018842 YkuI, C-terminal GTHT12_RS05490 c87d763e63e1027705a19126db62d745 405 Gene3D G3DSA:1.20.5.170 246 290 9.9E-21 T 06-07-2017 GTHT12_RS08495 1f328f42c0c327071d2afbd6e7974e57 276 Pfam PF02678 Pirin 45 116 4.7E-25 T 06-07-2017 IPR003829 Pirin, N-terminal domain GTHT12_RS08495 1f328f42c0c327071d2afbd6e7974e57 276 Gene3D G3DSA:2.60.120.10 4 249 1.5E-70 T 06-07-2017 IPR014710 RmlC-like jelly roll fold GTHT12_RS08495 1f328f42c0c327071d2afbd6e7974e57 276 PIRSF PIRSF006232 4 276 2.7E-77 T 06-07-2017 IPR012093 Pirin GTHT12_RS08495 1f328f42c0c327071d2afbd6e7974e57 276 SUPERFAMILY SSF51182 29 275 9.84E-75 T 06-07-2017 IPR011051 RmlC-like cupin domain GTHT12_RS08495 1f328f42c0c327071d2afbd6e7974e57 276 Pfam PF05726 Pirin C-terminal cupin domain 169 276 5.6E-30 T 06-07-2017 IPR008778 Pirin, C-terminal domain GTHT12_RS04180 2fb72b601ac2fe4a7a560729207d645c 76 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 76 1.9E-21 T 06-07-2017 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 GTHT12_RS04180 2fb72b601ac2fe4a7a560729207d645c 76 SUPERFAMILY SSF54285 1 76 4.67E-17 T 06-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp GTHT12_RS04180 2fb72b601ac2fe4a7a560729207d645c 76 Gene3D G3DSA:3.10.20.30 1 76 1.5E-19 T 06-07-2017 IPR012675 Beta-grasp domain GTHT12_RS04180 2fb72b601ac2fe4a7a560729207d645c 76 Pfam PF02597 ThiS family 5 76 2.4E-16 T 06-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 GTHT12_RS09160 d0e32a092bf40302cecdac25a0d16484 235 SUPERFAMILY SSF46955 4 82 5.95E-10 T 06-07-2017 IPR009061 Putative DNA-binding domain GTHT12_RS09160 d0e32a092bf40302cecdac25a0d16484 235 Pfam PF13411 MerR HTH family regulatory protein 4 68 8.6E-14 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS09160 d0e32a092bf40302cecdac25a0d16484 235 Gene3D G3DSA:1.10.1660.10 4 75 2.7E-9 T 06-07-2017 GTHT12_RS09160 d0e32a092bf40302cecdac25a0d16484 235 Gene3D G3DSA:1.10.1660.10 145 198 2.7E-9 T 06-07-2017 GTHT12_RS14655 c8cf77643a55daf196156be07362a688 98 Pfam PF03413 Peptidase propeptide and YPEB domain 29 95 1.7E-5 T 06-07-2017 IPR025711 PepSY domain GTHT12_RS07600 ef085b40fa0ad42f674270c8f415ff65 244 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 8 28 4.1E-6 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS07600 ef085b40fa0ad42f674270c8f415ff65 244 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 56 71 4.1E-6 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS07600 ef085b40fa0ad42f674270c8f415ff65 244 Gene3D G3DSA:3.40.50.300 6 166 2.7E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07600 ef085b40fa0ad42f674270c8f415ff65 244 SUPERFAMILY SSF52540 6 180 2.44E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07600 ef085b40fa0ad42f674270c8f415ff65 244 Pfam PF02421 Ferrous iron transport protein B 7 160 1.5E-62 T 06-07-2017 IPR011619 Ferrous iron transport protein B, N-terminal GO:0005525|GO:0015093|GO:0015684|GO:0016021 GTHT12_RS07600 ef085b40fa0ad42f674270c8f415ff65 244 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 161 1.6E-13 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 GTHT12_RS13915 66aea2e27bd3fc829e574ca10ac8d8f4 255 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 237 1.9E-114 T 06-07-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 GTHT12_RS13915 66aea2e27bd3fc829e574ca10ac8d8f4 255 SUPERFAMILY SSF55666 153 238 1.25E-20 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GTHT12_RS13915 66aea2e27bd3fc829e574ca10ac8d8f4 255 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 06-07-2017 IPR018336 Ribonuclease PH, conserved site GTHT12_RS13915 66aea2e27bd3fc829e574ca10ac8d8f4 255 SUPERFAMILY SSF54211 1 140 3.19E-45 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS13915 66aea2e27bd3fc829e574ca10ac8d8f4 255 Pfam PF03725 3' exoribonuclease family, domain 2 160 223 2.5E-8 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GTHT12_RS13915 66aea2e27bd3fc829e574ca10ac8d8f4 255 Gene3D G3DSA:3.30.230.70 2 237 1.0E-30 T 06-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GTHT12_RS13915 66aea2e27bd3fc829e574ca10ac8d8f4 255 Hamap MF_00564 Ribonuclease PH [rph]. 1 238 47.448 T 06-07-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 GTHT12_RS13915 66aea2e27bd3fc829e574ca10ac8d8f4 255 Pfam PF01138 3' exoribonuclease family, domain 1 10 140 5.9E-25 T 06-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 GTHT12_RS08430 04e357fc470a2877ebf3fae4c7d5a427 434 Gene3D G3DSA:1.20.1250.20 11 204 9.2E-42 T 06-07-2017 GTHT12_RS08430 04e357fc470a2877ebf3fae4c7d5a427 434 PIRSF PIRSF002808 4 425 1.7E-34 T 06-07-2017 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 GTHT12_RS08430 04e357fc470a2877ebf3fae4c7d5a427 434 Pfam PF07690 Major Facilitator Superfamily 17 374 5.6E-55 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS08430 04e357fc470a2877ebf3fae4c7d5a427 434 SUPERFAMILY SSF103473 7 414 5.75E-85 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS08430 04e357fc470a2877ebf3fae4c7d5a427 434 Gene3D G3DSA:1.20.1250.20 221 412 4.8E-32 T 06-07-2017 GTHT12_RS09990 0fc1e697c997adbad86f7c3794805c18 228 Gene3D G3DSA:3.40.225.10 2 228 3.5E-73 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal GTHT12_RS09990 0fc1e697c997adbad86f7c3794805c18 228 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 194 3.1E-49 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal GTHT12_RS09990 0fc1e697c997adbad86f7c3794805c18 228 TIGRFAM TIGR00760 araD: L-ribulose-5-phosphate 4-epimerase 1 228 9.3E-133 T 06-07-2017 IPR004661 L-ribulose-5-phosphate 4-epimerase GO:0008270|GO:0008742|GO:0019572 KEGG: 00040+5.1.3.4|KEGG: 00053+5.1.3.4|MetaCyc: PWY-6961 GTHT12_RS09990 0fc1e697c997adbad86f7c3794805c18 228 SMART SM01007 7 195 4.4E-71 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal GTHT12_RS09990 0fc1e697c997adbad86f7c3794805c18 228 SUPERFAMILY SSF53639 1 220 3.92E-73 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal GTHT12_RS06000 5bab3c74c14d2564de724b2fe2007e9a 428 SUPERFAMILY SSF51338 2 55 4.62E-28 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS06000 5bab3c74c14d2564de724b2fe2007e9a 428 SUPERFAMILY SSF51338 368 427 4.62E-28 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS06000 5bab3c74c14d2564de724b2fe2007e9a 428 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 16 425 5.7E-152 T 06-07-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 GTHT12_RS06000 5bab3c74c14d2564de724b2fe2007e9a 428 ProSitePatterns PS00482 Dihydroorotase signature 1. 59 67 - T 06-07-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 GTHT12_RS06000 5bab3c74c14d2564de724b2fe2007e9a 428 ProSitePatterns PS00483 Dihydroorotase signature 2. 304 315 - T 06-07-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 GTHT12_RS06000 5bab3c74c14d2564de724b2fe2007e9a 428 Gene3D G3DSA:2.30.40.10 3 69 4.6E-17 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS06000 5bab3c74c14d2564de724b2fe2007e9a 428 SUPERFAMILY SSF51556 56 368 5.41E-114 T 06-07-2017 IPR032466 Metal-dependent hydrolase GTHT12_RS06000 5bab3c74c14d2564de724b2fe2007e9a 428 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 426 47.736 T 06-07-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 GTHT12_RS06000 5bab3c74c14d2564de724b2fe2007e9a 428 Pfam PF01979 Amidohydrolase family 53 422 1.2E-62 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 GTHT12_RS06000 5bab3c74c14d2564de724b2fe2007e9a 428 Gene3D G3DSA:2.30.40.10 373 427 8.7E-5 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS06000 5bab3c74c14d2564de724b2fe2007e9a 428 Gene3D G3DSA:3.20.20.140 70 372 4.9E-116 T 06-07-2017 GTHT12_RS13720 63c099cfadb3e5902d22757b4b476323 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 163 191 3.6E-18 T 06-07-2017 IPR003004 GspF/PilC family GTHT12_RS13720 63c099cfadb3e5902d22757b4b476323 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 382 401 3.6E-18 T 06-07-2017 IPR003004 GspF/PilC family GTHT12_RS13720 63c099cfadb3e5902d22757b4b476323 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 64 76 3.6E-18 T 06-07-2017 IPR003004 GspF/PilC family GTHT12_RS13720 63c099cfadb3e5902d22757b4b476323 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 366 380 3.6E-18 T 06-07-2017 IPR003004 GspF/PilC family GTHT12_RS13720 63c099cfadb3e5902d22757b4b476323 403 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 163 191 - T 06-07-2017 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 GTHT12_RS13720 63c099cfadb3e5902d22757b4b476323 403 Pfam PF00482 Type II secretion system (T2SS), protein F 68 191 4.6E-36 T 06-07-2017 IPR018076 Type II secretion system F domain GTHT12_RS13720 63c099cfadb3e5902d22757b4b476323 403 Pfam PF00482 Type II secretion system (T2SS), protein F 272 393 6.9E-28 T 06-07-2017 IPR018076 Type II secretion system F domain GTHT12_RS12210 360de02df6408e974f491a79834a8151 395 Pfam PF01676 Metalloenzyme superfamily 7 379 6.0E-45 T 06-07-2017 IPR006124 Metalloenzyme GO:0003824|GO:0046872 GTHT12_RS12210 360de02df6408e974f491a79834a8151 395 PIRSF PIRSF001491 4 393 2.8E-167 T 06-07-2017 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 GTHT12_RS12210 360de02df6408e974f491a79834a8151 395 Hamap MF_00740 Phosphopentomutase [deoB]. 5 389 55.414 T 06-07-2017 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 GTHT12_RS12210 360de02df6408e974f491a79834a8151 395 Gene3D G3DSA:3.30.70.1250 102 218 9.5E-59 T 06-07-2017 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 GTHT12_RS12210 360de02df6408e974f491a79834a8151 395 Gene3D G3DSA:3.40.720.10 4 101 4.6E-81 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 GTHT12_RS12210 360de02df6408e974f491a79834a8151 395 Gene3D G3DSA:3.40.720.10 222 392 4.6E-81 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 GTHT12_RS12210 360de02df6408e974f491a79834a8151 395 SUPERFAMILY SSF53649 4 102 3.79E-79 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 GTHT12_RS12210 360de02df6408e974f491a79834a8151 395 SUPERFAMILY SSF53649 219 391 3.79E-79 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 GTHT12_RS12210 360de02df6408e974f491a79834a8151 395 TIGRFAM TIGR01696 deoB: phosphopentomutase 7 387 2.8E-202 T 06-07-2017 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 GTHT12_RS12210 360de02df6408e974f491a79834a8151 395 SUPERFAMILY SSF143856 102 218 2.88E-52 T 06-07-2017 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 GTHT12_RS13765 7fac2d6d29d402d2644f2613e7b09801 434 TIGRFAM TIGR01499 folC: bifunctional protein FolC 24 429 1.3E-132 T 06-07-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 GTHT12_RS13765 7fac2d6d29d402d2644f2613e7b09801 434 Gene3D G3DSA:3.40.1190.10 4 300 1.5E-100 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GTHT12_RS13765 7fac2d6d29d402d2644f2613e7b09801 434 Pfam PF02875 Mur ligase family, glutamate ligase domain 299 377 1.6E-11 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GTHT12_RS13765 7fac2d6d29d402d2644f2613e7b09801 434 SUPERFAMILY SSF53244 301 431 2.01E-28 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GTHT12_RS13765 7fac2d6d29d402d2644f2613e7b09801 434 PIRSF PIRSF001563 1 434 3.4E-157 T 06-07-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 GTHT12_RS13765 7fac2d6d29d402d2644f2613e7b09801 434 Pfam PF08245 Mur ligase middle domain 46 274 6.4E-17 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GTHT12_RS13765 7fac2d6d29d402d2644f2613e7b09801 434 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 143 158 - T 06-07-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 GTHT12_RS13765 7fac2d6d29d402d2644f2613e7b09801 434 Gene3D G3DSA:3.90.190.20 301 431 1.5E-33 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GTHT12_RS13765 7fac2d6d29d402d2644f2613e7b09801 434 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 44 67 - T 06-07-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 GTHT12_RS13765 7fac2d6d29d402d2644f2613e7b09801 434 SUPERFAMILY SSF53623 3 299 8.55E-97 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GTHT12_RS13540 1bd4041373a1c60d76bb76c8418dbb79 333 Gene3D G3DSA:1.10.8.60 184 256 3.7E-30 T 06-07-2017 GTHT12_RS13540 1bd4041373a1c60d76bb76c8418dbb79 333 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 252 332 4.0E-36 T 06-07-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 GTHT12_RS13540 1bd4041373a1c60d76bb76c8418dbb79 333 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 25 328 4.5E-146 T 06-07-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 GTHT12_RS13540 1bd4041373a1c60d76bb76c8418dbb79 333 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 6 236 1.1E-116 T 06-07-2017 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 GTHT12_RS13540 1bd4041373a1c60d76bb76c8418dbb79 333 SUPERFAMILY SSF46785 257 331 8.16E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS13540 1bd4041373a1c60d76bb76c8418dbb79 333 Gene3D G3DSA:3.40.50.300 22 179 3.5E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13540 1bd4041373a1c60d76bb76c8418dbb79 333 Gene3D G3DSA:1.10.10.10 258 329 1.2E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS13540 1bd4041373a1c60d76bb76c8418dbb79 333 SMART SM00382 52 180 1.0E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS13540 1bd4041373a1c60d76bb76c8418dbb79 333 SUPERFAMILY SSF52540 21 255 6.04E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13540 1bd4041373a1c60d76bb76c8418dbb79 333 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 333 173.576 T 06-07-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 GTHT12_RS13540 1bd4041373a1c60d76bb76c8418dbb79 333 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 254 327 8.9E-35 T 06-07-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 GTHT12_RS10860 08f2c8ff8e597e50ccae968cb8bbd767 250 SMART SM00382 92 224 3.6E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS10860 08f2c8ff8e597e50ccae968cb8bbd767 250 PIRSF PIRSF003073 1 245 4.2E-72 T 06-07-2017 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein GTHT12_RS10860 08f2c8ff8e597e50ccae968cb8bbd767 250 Gene3D G3DSA:3.40.50.300 85 223 3.9E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10860 08f2c8ff8e597e50ccae968cb8bbd767 250 SUPERFAMILY SSF52540 88 223 4.86E-24 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10860 08f2c8ff8e597e50ccae968cb8bbd767 250 Pfam PF01695 IstB-like ATP binding protein 48 223 2.9E-60 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 GTHT12_RS06080 dedd088a80c09b1f1dd2fcae9408821b 401 SUPERFAMILY SSF52507 1 179 8.37E-65 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 GTHT12_RS06080 dedd088a80c09b1f1dd2fcae9408821b 401 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 188 368 9.5E-73 T 06-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 GTHT12_RS06080 dedd088a80c09b1f1dd2fcae9408821b 401 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 3 393 9.3E-153 T 06-07-2017 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5 GTHT12_RS06080 dedd088a80c09b1f1dd2fcae9408821b 401 Gene3D G3DSA:3.40.50.1950 2 181 3.8E-70 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 GTHT12_RS06080 dedd088a80c09b1f1dd2fcae9408821b 401 SUPERFAMILY SSF102645 185 397 2.49E-76 T 06-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 GTHT12_RS06080 dedd088a80c09b1f1dd2fcae9408821b 401 Gene3D G3DSA:3.40.50.10300 186 396 7.0E-84 T 06-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 GTHT12_RS06080 dedd088a80c09b1f1dd2fcae9408821b 401 Pfam PF02441 Flavoprotein 5 132 9.8E-39 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 GTHT12_RS07640 7dc45d11933efc04aeef220b2b385c2b 129 Gene3D G3DSA:1.10.1660.10 3 57 7.5E-25 T 06-07-2017 GTHT12_RS07640 7dc45d11933efc04aeef220b2b385c2b 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 2.2E-6 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS07640 7dc45d11933efc04aeef220b2b385c2b 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 2.2E-6 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS07640 7dc45d11933efc04aeef220b2b385c2b 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 2.2E-6 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS07640 7dc45d11933efc04aeef220b2b385c2b 129 Pfam PF13411 MerR HTH family regulatory protein 4 69 1.7E-18 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS07640 7dc45d11933efc04aeef220b2b385c2b 129 SUPERFAMILY SSF46955 4 119 1.43E-28 T 06-07-2017 IPR009061 Putative DNA-binding domain GTHT12_RS07640 7dc45d11933efc04aeef220b2b385c2b 129 Gene3D G3DSA:1.10.1660.10 58 121 5.0E-16 T 06-07-2017 GTHT12_RS07640 7dc45d11933efc04aeef220b2b385c2b 129 SMART SM00422 4 72 9.5E-26 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS10575 e4ed42d922f53ce3402a4396c1b0f435 617 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 10 279 4.4E-71 T 06-07-2017 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 GTHT12_RS10575 e4ed42d922f53ce3402a4396c1b0f435 617 Gene3D G3DSA:1.50.10.20 278 611 1.9E-95 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid GTHT12_RS10575 e4ed42d922f53ce3402a4396c1b0f435 617 SUPERFAMILY SSF48239 32 284 7.46E-50 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid GTHT12_RS10575 e4ed42d922f53ce3402a4396c1b0f435 617 Gene3D G3DSA:1.50.10.20 29 277 5.8E-42 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid GTHT12_RS10575 e4ed42d922f53ce3402a4396c1b0f435 617 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 11 610 1.2E-125 T 06-07-2017 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 GTHT12_RS10575 e4ed42d922f53ce3402a4396c1b0f435 617 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 294 609 4.8E-91 T 06-07-2017 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 GTHT12_RS10575 e4ed42d922f53ce3402a4396c1b0f435 617 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 13 611 2.0E-135 T 06-07-2017 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00030+4.2.1.12|KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 GTHT12_RS10575 e4ed42d922f53ce3402a4396c1b0f435 617 SUPERFAMILY SSF48239 283 610 4.55E-83 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid GTHT12_RS14725 6eecbd484a9478eb149393936cce9401 433 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 7.1E-9 T 06-07-2017 GTHT12_RS14725 6eecbd484a9478eb149393936cce9401 433 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 168 7.1E-9 T 06-07-2017 GTHT12_RS14725 6eecbd484a9478eb149393936cce9401 433 Gene3D G3DSA:2.40.30.10 193 292 1.2E-23 T 06-07-2017 GTHT12_RS14725 6eecbd484a9478eb149393936cce9401 433 Pfam PF03486 HI0933-like protein 3 413 8.0E-154 T 06-07-2017 GTHT12_RS14725 6eecbd484a9478eb149393936cce9401 433 SUPERFAMILY SSF160996 193 361 8.76E-48 T 06-07-2017 GTHT12_RS14725 6eecbd484a9478eb149393936cce9401 433 SUPERFAMILY SSF51905 358 418 7.66E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS14725 6eecbd484a9478eb149393936cce9401 433 SUPERFAMILY SSF51905 1 194 7.66E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS14725 6eecbd484a9478eb149393936cce9401 433 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 5 413 9.3E-149 T 06-07-2017 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like GTHT12_RS14725 6eecbd484a9478eb149393936cce9401 433 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 6.4E-6 T 06-07-2017 GTHT12_RS14725 6eecbd484a9478eb149393936cce9401 433 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 6.4E-6 T 06-07-2017 GTHT12_RS14725 6eecbd484a9478eb149393936cce9401 433 Gene3D G3DSA:3.50.50.60 2 190 1.7E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS14725 6eecbd484a9478eb149393936cce9401 433 Gene3D G3DSA:3.50.50.60 360 416 1.7E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS16460 bf5d2e5af98718d4a934c041fd5cfeeb 506 Gene3D G3DSA:3.40.605.10 18 269 1.4E-95 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS16460 bf5d2e5af98718d4a934c041fd5cfeeb 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 294 305 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 GTHT12_RS16460 bf5d2e5af98718d4a934c041fd5cfeeb 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 GTHT12_RS16460 bf5d2e5af98718d4a934c041fd5cfeeb 506 SUPERFAMILY SSF53720 12 498 2.75E-166 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GTHT12_RS16460 bf5d2e5af98718d4a934c041fd5cfeeb 506 Pfam PF00171 Aldehyde dehydrogenase family 27 493 4.0E-169 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS16460 bf5d2e5af98718d4a934c041fd5cfeeb 506 Gene3D G3DSA:3.40.309.10 270 469 6.4E-62 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 GTHT12_RS10875 c82d606f2bc7d51e29eac22663c2fb1a 303 Gene3D G3DSA:3.40.50.300 2 229 7.3E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10875 c82d606f2bc7d51e29eac22663c2fb1a 303 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS10875 c82d606f2bc7d51e29eac22663c2fb1a 303 Pfam PF00005 ABC transporter 21 160 8.5E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS10875 c82d606f2bc7d51e29eac22663c2fb1a 303 SMART SM00382 29 206 5.4E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS10875 c82d606f2bc7d51e29eac22663c2fb1a 303 SUPERFAMILY SSF52540 2 233 4.05E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11130 847dfc62654da43ce58a6c997af8dc18 249 SUPERFAMILY SSF52317 4 240 5.72E-67 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS11130 847dfc62654da43ce58a6c997af8dc18 249 Pfam PF06283 Trehalose utilisation 6 221 5.1E-35 T 06-07-2017 IPR029010 ThuA-like domain GTHT12_RS11130 847dfc62654da43ce58a6c997af8dc18 249 PIRSF PIRSF030013 3 243 1.6E-124 T 06-07-2017 IPR009381 Trehalose catabolism protein, ThuA, prokaryote GTHT12_RS11130 847dfc62654da43ce58a6c997af8dc18 249 Gene3D G3DSA:3.40.50.880 2 244 2.8E-102 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS08150 07ad160229299335b455cf02799d96e4 148 SUPERFAMILY SSF143865 58 136 3.53E-9 T 06-07-2017 GTHT12_RS08150 07ad160229299335b455cf02799d96e4 148 Pfam PF01544 CorA-like Mg2+ transporter protein 63 129 2.2E-7 T 06-07-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 GTHT12_RS14550 26a1e8edd1750fad94cb721a251b38d6 158 SUPERFAMILY SSF55785 19 123 3.66E-14 T 06-07-2017 IPR000014 PAS domain GTHT12_RS14550 26a1e8edd1750fad94cb721a251b38d6 158 SMART SM00091 23 89 8.5E-6 T 06-07-2017 IPR000014 PAS domain GTHT12_RS14550 26a1e8edd1750fad94cb721a251b38d6 158 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 22 138 2.0E-12 T 06-07-2017 IPR000014 PAS domain GTHT12_RS14550 26a1e8edd1750fad94cb721a251b38d6 158 Gene3D G3DSA:3.30.450.20 21 123 1.1E-14 T 06-07-2017 GTHT12_RS14550 26a1e8edd1750fad94cb721a251b38d6 158 Pfam PF13426 PAS domain 34 130 1.1E-10 T 06-07-2017 IPR000014 PAS domain GTHT12_RS07150 635ca5d56d9a5c6876623378ef2e9bf9 632 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 114 120 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 GTHT12_RS07150 635ca5d56d9a5c6876623378ef2e9bf9 632 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 111 123 7.0E-12 T 06-07-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 GTHT12_RS07150 635ca5d56d9a5c6876623378ef2e9bf9 632 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 168 187 7.0E-12 T 06-07-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 GTHT12_RS07150 635ca5d56d9a5c6876623378ef2e9bf9 632 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 421 435 7.0E-12 T 06-07-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 GTHT12_RS07150 635ca5d56d9a5c6876623378ef2e9bf9 632 Pfam PF01555 DNA methylase 111 452 5.7E-33 T 06-07-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 GTHT12_RS07150 635ca5d56d9a5c6876623378ef2e9bf9 632 PIRSF PIRSF015855 1 631 2.7E-175 T 06-07-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 GTHT12_RS07150 635ca5d56d9a5c6876623378ef2e9bf9 632 Gene3D G3DSA:3.40.50.150 361 509 6.8E-59 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS07150 635ca5d56d9a5c6876623378ef2e9bf9 632 Gene3D G3DSA:3.40.50.150 87 265 6.8E-59 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS07150 635ca5d56d9a5c6876623378ef2e9bf9 632 SUPERFAMILY SSF53335 81 306 3.33E-58 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS07150 635ca5d56d9a5c6876623378ef2e9bf9 632 SUPERFAMILY SSF53335 377 476 3.33E-58 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS00845 3134854d438dddb2cbe27cc591a7b5bc 338 SUPERFAMILY SSF52540 97 336 1.3E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00845 3134854d438dddb2cbe27cc591a7b5bc 338 Gene3D G3DSA:3.40.50.300 92 334 1.3E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00845 3134854d438dddb2cbe27cc591a7b5bc 338 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 97 334 2.6E-85 T 06-07-2017 IPR019591 Mrp/NBP35 ATP-binding protein GTHT12_RS00845 3134854d438dddb2cbe27cc591a7b5bc 338 SUPERFAMILY SSF117916 1 74 3.27E-6 T 06-07-2017 GTHT12_RS00845 3134854d438dddb2cbe27cc591a7b5bc 338 Hamap MF_02040 Iron-sulfur cluster carrier protein. 87 335 33.369 T 06-07-2017 IPR019591 Mrp/NBP35 ATP-binding protein GTHT12_RS00845 3134854d438dddb2cbe27cc591a7b5bc 338 ProSitePatterns PS01215 Mrp family signature. 200 216 - T 06-07-2017 IPR000808 Mrp, conserved site GO:0005524 GTHT12_RS00845 3134854d438dddb2cbe27cc591a7b5bc 338 Pfam PF01883 Domain of unknown function DUF59 5 67 3.9E-7 T 06-07-2017 IPR002744 Domain of unknown function DUF59 GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 SUPERFAMILY SSF55186 68 243 7.46E-67 T 06-07-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 SUPERFAMILY SSF81271 5 64 2.62E-16 T 06-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 PRINTS PR01047 Threonyl-tRNA synthetase signature 542 554 9.9E-48 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 PRINTS PR01047 Threonyl-tRNA synthetase signature 366 389 9.9E-48 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 PRINTS PR01047 Threonyl-tRNA synthetase signature 333 361 9.9E-48 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 PRINTS PR01047 Threonyl-tRNA synthetase signature 515 528 9.9E-48 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 PRINTS PR01047 Threonyl-tRNA synthetase signature 472 500 9.9E-48 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 Gene3D G3DSA:3.10.20.30 5 66 6.0E-24 T 06-07-2017 IPR012675 Beta-grasp domain GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 69 643 35.852 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 Gene3D G3DSA:3.40.50.800 539 644 9.1E-38 T 06-07-2017 IPR004154 Anticodon-binding GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 SUPERFAMILY SSF55681 245 534 1.65E-97 T 06-07-2017 GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 Pfam PF02824 TGS domain 5 64 2.6E-13 T 06-07-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 SMART SM00863 172 221 4.8E-26 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 Pfam PF03129 Anticodon binding domain 549 639 1.5E-25 T 06-07-2017 IPR004154 Anticodon-binding GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 Gene3D G3DSA:3.30.54.20 133 189 5.0E-23 T 06-07-2017 GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 SUPERFAMILY SSF52954 535 640 1.15E-32 T 06-07-2017 IPR004154 Anticodon-binding GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 75 640 3.0E-241 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 Gene3D G3DSA:3.30.980.10 69 132 4.8E-42 T 06-07-2017 GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 Gene3D G3DSA:3.30.980.10 190 225 4.8E-42 T 06-07-2017 GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 327 537 2.1E-34 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 172 221 5.8E-17 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 GTHT12_RS14155 3864d2d29f566f79cb121b0aa7286254 649 Gene3D G3DSA:3.30.930.10 244 538 2.2E-106 T 06-07-2017 GTHT12_RS02715 5f2eba411bfdc22711584e9f9437df1e 141 SMART SM00860 21 132 3.6E-11 T 06-07-2017 IPR018958 SMI1/KNR4-like domain GTHT12_RS02715 5f2eba411bfdc22711584e9f9437df1e 141 Gene3D G3DSA:3.40.1580.10 1 140 2.6E-40 T 06-07-2017 IPR018958 SMI1/KNR4-like domain GTHT12_RS02715 5f2eba411bfdc22711584e9f9437df1e 141 Pfam PF14567 SMI1-KNR4 cell-wall 5 135 5.1E-33 T 06-07-2017 GTHT12_RS02715 5f2eba411bfdc22711584e9f9437df1e 141 SUPERFAMILY SSF160631 3 140 2.62E-35 T 06-07-2017 GTHT12_RS11655 3dd81078ee356fa9822e95f5fb03df6b 508 Pfam PF04715 Anthranilate synthase component I, N terminal region 28 168 1.4E-30 T 06-07-2017 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 GTHT12_RS11655 3dd81078ee356fa9822e95f5fb03df6b 508 Gene3D G3DSA:3.60.120.10 16 499 1.0E-161 T 06-07-2017 IPR005801 ADC synthase GO:0009058 GTHT12_RS11655 3dd81078ee356fa9822e95f5fb03df6b 508 PRINTS PR00095 Anthranilate synthase component I signature 427 441 7.8E-22 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 GTHT12_RS11655 3dd81078ee356fa9822e95f5fb03df6b 508 PRINTS PR00095 Anthranilate synthase component I signature 347 360 7.8E-22 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 GTHT12_RS11655 3dd81078ee356fa9822e95f5fb03df6b 508 PRINTS PR00095 Anthranilate synthase component I signature 442 456 7.8E-22 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 GTHT12_RS11655 3dd81078ee356fa9822e95f5fb03df6b 508 PRINTS PR00095 Anthranilate synthase component I signature 333 346 7.8E-22 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 GTHT12_RS11655 3dd81078ee356fa9822e95f5fb03df6b 508 SUPERFAMILY SSF56322 17 496 3.27E-149 T 06-07-2017 IPR005801 ADC synthase GO:0009058 GTHT12_RS11655 3dd81078ee356fa9822e95f5fb03df6b 508 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 28 494 1.2E-165 T 06-07-2017 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 GTHT12_RS11655 3dd81078ee356fa9822e95f5fb03df6b 508 Pfam PF00425 chorismate binding enzyme 232 485 1.7E-95 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 Gene3D G3DSA:3.30.390.30 341 472 1.3E-47 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 354 462 2.7E-35 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 Gene3D G3DSA:3.50.50.60 3 149 2.1E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 473 3.6E-178 T 06-07-2017 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 2.0E-68 T 06-07-2017 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 350 371 2.0E-68 T 06-07-2017 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 286 2.0E-68 T 06-07-2017 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 415 430 2.0E-68 T 06-07-2017 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.0E-68 T 06-07-2017 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 314 321 2.0E-68 T 06-07-2017 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 437 457 2.0E-68 T 06-07-2017 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 2.0E-68 T 06-07-2017 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.0E-68 T 06-07-2017 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 299 321 2.3E-35 T 06-07-2017 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.3E-35 T 06-07-2017 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 2.3E-35 T 06-07-2017 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 2.3E-35 T 06-07-2017 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 287 2.3E-35 T 06-07-2017 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 Gene3D G3DSA:3.50.50.60 150 340 8.7E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 SUPERFAMILY SSF51905 1 380 4.15E-63 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 SUPERFAMILY SSF55424 350 472 5.33E-41 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 334 3.9E-63 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 PIRSF PIRSF000350 1 470 4.4E-85 T 06-07-2017 GTHT12_RS12435 5a0d94954b3f6f7420603b24917c6e85 473 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 06-07-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 GTHT12_RS18050 f46e5c816a0d2127d43874d6a014dbba 373 Pfam PF12698 ABC-2 family transporter protein 19 363 2.5E-32 T 06-07-2017 GTHT12_RS12180 34868fdf5b5210f6360ef7129f881884 250 PIRSF PIRSF000770 9 250 4.0E-37 T 06-07-2017 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 GTHT12_RS12180 34868fdf5b5210f6360ef7129f881884 250 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 248 9.4E-39 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS12180 34868fdf5b5210f6360ef7129f881884 250 Gene3D G3DSA:1.10.10.10 194 248 2.4E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12180 34868fdf5b5210f6360ef7129f881884 250 Gene3D G3DSA:1.10.601.10 11 102 2.4E-34 T 06-07-2017 GTHT12_RS12180 34868fdf5b5210f6360ef7129f881884 250 PRINTS PR00046 Major sigma-70 factor signature 233 244 1.1E-10 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS12180 34868fdf5b5210f6360ef7129f881884 250 PRINTS PR00046 Major sigma-70 factor signature 59 72 1.1E-10 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS12180 34868fdf5b5210f6360ef7129f881884 250 PRINTS PR00046 Major sigma-70 factor signature 201 213 1.1E-10 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS12180 34868fdf5b5210f6360ef7129f881884 250 PRINTS PR00046 Major sigma-70 factor signature 83 91 1.1E-10 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS12180 34868fdf5b5210f6360ef7129f881884 250 PRINTS PR00046 Major sigma-70 factor signature 218 233 1.1E-10 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS12180 34868fdf5b5210f6360ef7129f881884 250 Pfam PF04542 Sigma-70 region 2 36 102 1.3E-18 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS12180 34868fdf5b5210f6360ef7129f881884 250 Pfam PF04539 Sigma-70 region 3 115 183 4.3E-14 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS12180 34868fdf5b5210f6360ef7129f881884 250 SUPERFAMILY SSF88946 11 103 1.15E-34 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS12180 34868fdf5b5210f6360ef7129f881884 250 SUPERFAMILY SSF88659 169 248 6.54E-18 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS12180 34868fdf5b5210f6360ef7129f881884 250 Pfam PF04545 Sigma-70, region 4 197 246 4.3E-16 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS12180 34868fdf5b5210f6360ef7129f881884 250 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 218 244 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS12180 34868fdf5b5210f6360ef7129f881884 250 Gene3D G3DSA:1.10.10.10 103 157 6.7E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12180 34868fdf5b5210f6360ef7129f881884 250 TIGRFAM TIGR02885 spore_sigF: RNA polymerase sigma-F factor 20 248 1.3E-114 T 06-07-2017 IPR014236 RNA polymerase sigma-F type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS12180 34868fdf5b5210f6360ef7129f881884 250 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 28 248 4.7E-91 T 06-07-2017 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS12180 34868fdf5b5210f6360ef7129f881884 250 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 59 72 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS12180 34868fdf5b5210f6360ef7129f881884 250 SUPERFAMILY SSF88659 107 182 1.44E-17 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS01820 47eb8567dd6348473926caafed62bf46 353 SUPERFAMILY SSF56266 3 342 2.46E-102 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 GTHT12_RS01820 47eb8567dd6348473926caafed62bf46 353 Gene3D G3DSA:3.60.70.12 3 345 2.0E-123 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 GTHT12_RS01820 47eb8567dd6348473926caafed62bf46 353 Pfam PF03576 Peptidase family S58 21 333 1.6E-111 T 06-07-2017 IPR005321 Peptidase S58, DmpA GTHT12_RS09930 1368ae1f4cfa95498ac02c72405f865b 576 Gene3D G3DSA:3.30.565.10 413 572 6.6E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS09930 1368ae1f4cfa95498ac02c72405f865b 576 PRINTS PR00344 Bacterial sensor protein C-terminal signature 528 546 1.0E-5 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS09930 1368ae1f4cfa95498ac02c72405f865b 576 PRINTS PR00344 Bacterial sensor protein C-terminal signature 496 510 1.0E-5 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS09930 1368ae1f4cfa95498ac02c72405f865b 576 PRINTS PR00344 Bacterial sensor protein C-terminal signature 557 570 1.0E-5 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS09930 1368ae1f4cfa95498ac02c72405f865b 576 SMART SM00387 454 573 3.4E-4 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS09930 1368ae1f4cfa95498ac02c72405f865b 576 SUPERFAMILY SSF55874 418 570 4.71E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS09930 1368ae1f4cfa95498ac02c72405f865b 576 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 462 571 4.7E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS09930 1368ae1f4cfa95498ac02c72405f865b 576 Pfam PF00672 HAMP domain 279 345 2.8E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS09930 1368ae1f4cfa95498ac02c72405f865b 576 Pfam PF06580 Histidine kinase 363 443 1.5E-26 T 06-07-2017 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 GTHT12_RS17145 c1ea7cca1815fb0d2e340ca25739454a 377 Gene3D G3DSA:3.90.350.10 174 295 2.7E-5 T 06-07-2017 IPR014736 Transposase, Tn5-like, core GTHT12_RS17145 c1ea7cca1815fb0d2e340ca25739454a 377 Pfam PF01609 Transposase DDE domain 110 320 1.6E-32 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 GTHT12_RS17145 c1ea7cca1815fb0d2e340ca25739454a 377 SUPERFAMILY SSF53098 84 335 9.1E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS15310 4b5798783e4f877f1985ef80e0e50352 88 Pfam PF08958 Domain of unknown function (DUF1871) 10 85 7.0E-32 T 06-07-2017 IPR015053 Protein of unknown function DUF1871 GTHT12_RS15310 4b5798783e4f877f1985ef80e0e50352 88 Gene3D G3DSA:1.10.340.20 1 85 5.0E-33 T 06-07-2017 IPR023162 Apc36109-like domain GTHT12_RS15310 4b5798783e4f877f1985ef80e0e50352 88 SUPERFAMILY SSF116922 4 80 1.2E-23 T 06-07-2017 IPR023162 Apc36109-like domain GTHT12_RS15310 4b5798783e4f877f1985ef80e0e50352 88 ProDom PD062625 YUGE 10 86 2.0E-27 T 06-07-2017 IPR015053 Protein of unknown function DUF1871 GTHT12_RS01340 44b71dddee0875fdb68b7198647a67c5 162 Pfam PF10263 SprT-like family 7 147 5.8E-23 T 06-07-2017 IPR006640 SprT-like GTHT12_RS01340 44b71dddee0875fdb68b7198647a67c5 162 Hamap MF_00745 Protein SprT-like. 4 149 40.29 T 06-07-2017 IPR023524 Uncharacterised protein family SprT-like GTHT12_RS01340 44b71dddee0875fdb68b7198647a67c5 162 SMART SM00731 4 149 2.4E-51 T 06-07-2017 IPR006640 SprT-like GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 Pfam PF01751 Toprim domain 424 533 2.2E-16 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 Hamap MF_00939 DNA topoisomerase 4 subunit B [parE]. 7 639 48.783 T 06-07-2017 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 Gene3D G3DSA:3.30.230.10 222 393 1.5E-65 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 Pfam PF00204 DNA gyrase B 223 393 6.9E-58 T 06-07-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 SUPERFAMILY SSF56719 400 633 3.92E-86 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 SMART SM00387 34 178 6.2E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 ProSitePatterns PS00177 DNA topoisomerase II signature. 427 435 - T 06-07-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 PRINTS PR01159 DNA gyrase subunit B signature 198 211 7.0E-60 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 PRINTS PR01159 DNA gyrase subunit B signature 9 19 7.0E-60 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 PRINTS PR01159 DNA gyrase subunit B signature 222 244 7.0E-60 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 PRINTS PR01159 DNA gyrase subunit B signature 475 484 7.0E-60 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 PRINTS PR01159 DNA gyrase subunit B signature 313 329 7.0E-60 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 PRINTS PR01159 DNA gyrase subunit B signature 610 626 7.0E-60 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 PRINTS PR01159 DNA gyrase subunit B signature 594 606 7.0E-60 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 PRINTS PR01159 DNA gyrase subunit B signature 183 198 7.0E-60 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 PRINTS PR01159 DNA gyrase subunit B signature 363 377 7.0E-60 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 PRINTS PR01159 DNA gyrase subunit B signature 377 397 7.0E-60 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 TIGRFAM TIGR01058 parE_Gpos: DNA topoisomerase IV, B subunit 8 640 0.0 T 06-07-2017 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 Gene3D G3DSA:3.40.50.670 410 623 2.7E-88 T 06-07-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 PRINTS PR00418 DNA topoisomerase II family signature 491 507 1.3E-70 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 PRINTS PR00418 DNA topoisomerase II family signature 529 541 1.3E-70 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 PRINTS PR00418 DNA topoisomerase II family signature 425 439 1.3E-70 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 PRINTS PR00418 DNA topoisomerase II family signature 269 282 1.3E-70 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 PRINTS PR00418 DNA topoisomerase II family signature 73 86 1.3E-70 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 PRINTS PR00418 DNA topoisomerase II family signature 115 129 1.3E-70 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 PRINTS PR00418 DNA topoisomerase II family signature 573 589 1.3E-70 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 PRINTS PR00418 DNA topoisomerase II family signature 38 53 1.3E-70 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 PRINTS PR00418 DNA topoisomerase II family signature 509 526 1.3E-70 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 Gene3D G3DSA:3.30.565.10 9 220 2.1E-89 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 SUPERFAMILY SSF55874 8 220 2.71E-70 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 SUPERFAMILY SSF54211 223 393 1.01E-53 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 570 630 1.3E-30 T 06-07-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 SMART SM00433 38 634 0.0 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 GTHT12_RS09170 70739bd11208e036aea11e304037da73 645 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 34 177 5.1E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS12290 2068bd1ddd60e26bf8321d948af418f8 279 Gene3D G3DSA:3.40.50.720 4 161 3.1E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS12290 2068bd1ddd60e26bf8321d948af418f8 279 PIRSF PIRSF000193 4 271 3.0E-79 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 GTHT12_RS12290 2068bd1ddd60e26bf8321d948af418f8 279 SUPERFAMILY SSF48179 163 270 9.01E-35 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GTHT12_RS12290 2068bd1ddd60e26bf8321d948af418f8 279 Gene3D G3DSA:1.10.3730.10 163 268 3.2E-38 T 06-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 GTHT12_RS12290 2068bd1ddd60e26bf8321d948af418f8 279 SUPERFAMILY SSF51735 5 162 1.61E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS12290 2068bd1ddd60e26bf8321d948af418f8 279 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 5 268 26.877 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 GTHT12_RS12290 2068bd1ddd60e26bf8321d948af418f8 279 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 224 246 - T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 GTHT12_RS12290 2068bd1ddd60e26bf8321d948af418f8 279 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 7 101 6.7E-22 T 06-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal GTHT12_RS12290 2068bd1ddd60e26bf8321d948af418f8 279 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 164 268 2.9E-36 T 06-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 GTHT12_RS12290 2068bd1ddd60e26bf8321d948af418f8 279 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 7 268 7.5E-87 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 GTHT12_RS13820 e933d97722a4dda602696979ad82ba7c 455 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 420 5.9E-155 T 06-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 GTHT12_RS13820 e933d97722a4dda602696979ad82ba7c 455 PIRSF PIRSF000445 1 434 2.3E-158 T 06-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 GTHT12_RS13820 e933d97722a4dda602696979ad82ba7c 455 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 171 306 2.5E-45 T 06-07-2017 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase GTHT12_RS13820 e933d97722a4dda602696979ad82ba7c 455 Gene3D G3DSA:3.40.50.720 163 311 1.1E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS13820 e933d97722a4dda602696979ad82ba7c 455 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 06-07-2017 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 GTHT12_RS13820 e933d97722a4dda602696979ad82ba7c 455 SUPERFAMILY SSF69075 318 420 1.24E-17 T 06-07-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 GTHT12_RS13820 e933d97722a4dda602696979ad82ba7c 455 SUPERFAMILY SSF51735 163 315 1.0E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS13820 e933d97722a4dda602696979ad82ba7c 455 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 417 30.141 T 06-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 GTHT12_RS13820 e933d97722a4dda602696979ad82ba7c 455 SUPERFAMILY SSF69742 2 158 2.48E-48 T 06-07-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 GTHT12_RS13820 e933d97722a4dda602696979ad82ba7c 455 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 3.8E-47 T 06-07-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 GTHT12_RS13820 e933d97722a4dda602696979ad82ba7c 455 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 321 419 1.1E-22 T 06-07-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 GTHT12_RS06015 2fe9f70904c9e5e50c6b59422def5a60 257 Gene3D G3DSA:3.40.50.80 107 207 1.7E-38 T 06-07-2017 GTHT12_RS06015 2fe9f70904c9e5e50c6b59422def5a60 257 PIRSF PIRSF006816 1 257 5.7E-71 T 06-07-2017 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 GTHT12_RS06015 2fe9f70904c9e5e50c6b59422def5a60 257 SUPERFAMILY SSF52343 95 256 3.01E-35 T 06-07-2017 GTHT12_RS06015 2fe9f70904c9e5e50c6b59422def5a60 257 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 216 255 1.3E-16 T 06-07-2017 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain GTHT12_RS06015 2fe9f70904c9e5e50c6b59422def5a60 257 Pfam PF00175 Oxidoreductase NAD-binding domain 113 202 3.7E-5 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 GTHT12_RS06015 2fe9f70904c9e5e50c6b59422def5a60 257 Gene3D G3DSA:2.10.240.10 216 256 1.5E-18 T 06-07-2017 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain GTHT12_RS06015 2fe9f70904c9e5e50c6b59422def5a60 257 Pfam PF00970 Oxidoreductase FAD-binding domain 9 98 4.3E-6 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 GTHT12_RS06015 2fe9f70904c9e5e50c6b59422def5a60 257 SUPERFAMILY SSF63380 4 100 4.84E-22 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 GTHT12_RS06015 2fe9f70904c9e5e50c6b59422def5a60 257 Gene3D G3DSA:2.40.30.10 4 98 4.8E-31 T 06-07-2017 GTHT12_RS06015 2fe9f70904c9e5e50c6b59422def5a60 257 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 4 257 39.417 T 06-07-2017 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit GTHT12_RS07105 0881d4709ca0469713b66a2deb9d51d5 321 Pfam PF00294 pfkB family carbohydrate kinase 15 301 1.1E-48 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB GTHT12_RS07105 0881d4709ca0469713b66a2deb9d51d5 321 SUPERFAMILY SSF53613 15 301 1.48E-56 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS07105 0881d4709ca0469713b66a2deb9d51d5 321 Gene3D G3DSA:3.40.1190.20 15 313 5.9E-73 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS07105 0881d4709ca0469713b66a2deb9d51d5 321 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 49 73 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 GTHT12_RS06590 ebcfec58390f8ad9f6e132fa31f94f88 415 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 35 58 - T 06-07-2017 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 GTHT12_RS06590 ebcfec58390f8ad9f6e132fa31f94f88 415 SUPERFAMILY SSF63411 6 220 3.06E-62 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 GTHT12_RS06590 ebcfec58390f8ad9f6e132fa31f94f88 415 Gene3D G3DSA:3.30.830.10 220 405 7.0E-56 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 GTHT12_RS06590 ebcfec58390f8ad9f6e132fa31f94f88 415 Gene3D G3DSA:3.30.830.10 6 214 5.5E-60 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 GTHT12_RS06590 ebcfec58390f8ad9f6e132fa31f94f88 415 Pfam PF05193 Peptidase M16 inactive domain 168 339 2.0E-43 T 06-07-2017 IPR007863 Peptidase M16, C-terminal GTHT12_RS06590 ebcfec58390f8ad9f6e132fa31f94f88 415 SUPERFAMILY SSF63411 229 403 7.33E-49 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 GTHT12_RS06590 ebcfec58390f8ad9f6e132fa31f94f88 415 Pfam PF00675 Insulinase (Peptidase family M16) 14 161 3.7E-47 T 06-07-2017 IPR011765 Peptidase M16, N-terminal GTHT12_RS00235 116a0bef1d0b08f0f4ac32071dafb66b 85 Gene3D G3DSA:2.30.30.100 1 77 2.6E-32 T 06-07-2017 GTHT12_RS00235 116a0bef1d0b08f0f4ac32071dafb66b 85 Pfam PF06257 Biofilm formation stimulator VEG 4 74 3.6E-30 T 06-07-2017 IPR009366 Protein Veg GO:0042710 GTHT12_RS00235 116a0bef1d0b08f0f4ac32071dafb66b 85 PIRSF PIRSF037257 1 84 6.5E-35 T 06-07-2017 IPR009366 Protein Veg GO:0042710 GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 Gene3D G3DSA:3.30.70.1430 41 135 6.7E-25 T 06-07-2017 GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 Pfam PF00873 AcrB/AcrD/AcrF family 5 244 4.8E-47 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 Pfam PF00873 AcrB/AcrD/AcrF family 298 1046 3.1E-165 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 SUPERFAMILY SSF82693 41 132 8.37E-21 T 06-07-2017 GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 SUPERFAMILY SSF82714 745 829 1.57E-8 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 Gene3D G3DSA:3.30.70.1320 136 177 6.8E-14 T 06-07-2017 GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 Gene3D G3DSA:3.30.70.1320 314 342 6.8E-14 T 06-07-2017 GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 Gene3D G3DSA:1.20.1640.10 343 543 3.4E-53 T 06-07-2017 GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 SUPERFAMILY SSF82866 334 537 3.92E-43 T 06-07-2017 GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 SUPERFAMILY SSF82714 182 246 2.49E-8 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 Gene3D G3DSA:3.30.2090.10 746 829 2.0E-9 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 Gene3D G3DSA:3.30.2090.10 182 252 6.8E-7 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 Gene3D G3DSA:3.30.2090.10 298 309 6.8E-7 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 Gene3D G3DSA:1.10.3850.10 836 1050 1.9E-54 T 06-07-2017 GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 SUPERFAMILY SSF82866 830 1054 1.16E-45 T 06-07-2017 GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 PRINTS PR00702 Acriflavin resistance protein family signature 585 602 3.4E-44 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 3.4E-44 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 PRINTS PR00702 Acriflavin resistance protein family signature 428 452 3.4E-44 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 3.4E-44 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 PRINTS PR00702 Acriflavin resistance protein family signature 484 507 3.4E-44 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 PRINTS PR00702 Acriflavin resistance protein family signature 400 421 3.4E-44 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 PRINTS PR00702 Acriflavin resistance protein family signature 509 532 3.4E-44 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 SUPERFAMILY SSF82693 134 180 8.63E-18 T 06-07-2017 GTHT12_RS15260 bb6652fae0d50bb5c82912925f513c5c 1060 SUPERFAMILY SSF82693 312 366 8.63E-18 T 06-07-2017 GTHT12_RS01165 127d3568e299af3820bceb8cb68b5d69 308 Pfam PF01497 Periplasmic binding protein 69 283 9.5E-28 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 GTHT12_RS01165 127d3568e299af3820bceb8cb68b5d69 308 SUPERFAMILY SSF53807 40 303 7.85E-53 T 06-07-2017 GTHT12_RS01165 127d3568e299af3820bceb8cb68b5d69 308 Gene3D G3DSA:3.40.50.1980 156 305 5.0E-24 T 06-07-2017 GTHT12_RS01165 127d3568e299af3820bceb8cb68b5d69 308 Gene3D G3DSA:3.40.50.1980 39 155 3.9E-29 T 06-07-2017 GTHT12_RS07245 fa9d6a39c1b29d370ed4b123d0210a24 264 TIGRFAM TIGR03331 SAM_DCase_Eco: S-adenosylmethionine decarboxylase proenzyme 7 260 4.1E-138 T 06-07-2017 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 GTHT12_RS07245 fa9d6a39c1b29d370ed4b123d0210a24 264 SUPERFAMILY SSF56276 46 172 1.57E-24 T 06-07-2017 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 GTHT12_RS07245 fa9d6a39c1b29d370ed4b123d0210a24 264 Hamap MF_00465 S-adenosylmethionine decarboxylase proenzyme [speD]. 1 264 158.163 T 06-07-2017 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 GTHT12_RS07245 fa9d6a39c1b29d370ed4b123d0210a24 264 Pfam PF02675 S-adenosylmethionine decarboxylase 36 168 3.7E-31 T 06-07-2017 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 GTHT12_RS07245 fa9d6a39c1b29d370ed4b123d0210a24 264 PIRSF PIRSF001356 1 262 4.4E-132 T 06-07-2017 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 GTHT12_RS07245 fa9d6a39c1b29d370ed4b123d0210a24 264 Gene3D G3DSA:3.60.90.10 36 185 6.1E-47 T 06-07-2017 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 GTHT12_RS18715 505a572a73481f98d90de0ee62e0a8c2 299 SUPERFAMILY SSF53067 4 284 4.25E-45 T 06-07-2017 GTHT12_RS18715 505a572a73481f98d90de0ee62e0a8c2 299 Pfam PF00480 ROK family 3 286 1.1E-65 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 GTHT12_RS18715 505a572a73481f98d90de0ee62e0a8c2 299 Gene3D G3DSA:3.30.420.40 103 288 7.5E-69 T 06-07-2017 GTHT12_RS18715 505a572a73481f98d90de0ee62e0a8c2 299 Gene3D G3DSA:3.30.420.40 2 102 2.0E-32 T 06-07-2017 GTHT12_RS18715 505a572a73481f98d90de0ee62e0a8c2 299 ProSitePatterns PS01125 ROK family signature. 128 153 - T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 GTHT12_RS00775 2d90278b870796045f72bf79a382d7c8 72 SMART SM00316 4 72 4.7E-7 T 06-07-2017 IPR022967 RNA-binding domain, S1 GTHT12_RS00775 2d90278b870796045f72bf79a382d7c8 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 28.62 T 06-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 GTHT12_RS00775 2d90278b870796045f72bf79a382d7c8 72 Gene3D G3DSA:2.40.50.140 1 72 2.5E-41 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS00775 2d90278b870796045f72bf79a382d7c8 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 3.5E-40 T 06-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 GTHT12_RS00775 2d90278b870796045f72bf79a382d7c8 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 1.3E-29 T 06-07-2017 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 GTHT12_RS00775 2d90278b870796045f72bf79a382d7c8 72 SUPERFAMILY SSF50249 1 71 1.37E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS11660 1b4d5959351f7184900d951d58e8308e 126 Gene3D G3DSA:3.30.1330.40 1 119 5.5E-49 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like GTHT12_RS11660 1b4d5959351f7184900d951d58e8308e 126 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 2 118 1.0E-45 T 06-07-2017 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 GTHT12_RS11660 1b4d5959351f7184900d951d58e8308e 126 Pfam PF07736 Chorismate mutase type I 2 118 1.0E-45 T 06-07-2017 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 GTHT12_RS11660 1b4d5959351f7184900d951d58e8308e 126 SUPERFAMILY SSF55298 1 125 1.33E-47 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like GTHT12_RS11660 1b4d5959351f7184900d951d58e8308e 126 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 8 126 5.0E-56 T 06-07-2017 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 GTHT12_RS11660 1b4d5959351f7184900d951d58e8308e 126 PIRSF PIRSF005965 1 124 4.0E-50 T 06-07-2017 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 GTHT12_RS07055 ff11eb1cd138bef6638f9a320092e84e 160 Pfam PF03061 Thioesterase superfamily 57 140 2.3E-8 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 GTHT12_RS07055 ff11eb1cd138bef6638f9a320092e84e 160 SUPERFAMILY SSF54637 6 151 2.31E-30 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS07055 ff11eb1cd138bef6638f9a320092e84e 160 Gene3D G3DSA:3.10.129.10 8 156 1.1E-53 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS02990 47dc1dc9a2d563799d59507f6acc47ed 580 Gene3D G3DSA:1.20.1560.10 5 322 9.1E-83 T 06-07-2017 GTHT12_RS02990 47dc1dc9a2d563799d59507f6acc47ed 580 SUPERFAMILY SSF90123 6 325 9.55E-79 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GTHT12_RS02990 47dc1dc9a2d563799d59507f6acc47ed 580 Pfam PF00005 ABC transporter 359 508 1.1E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS02990 47dc1dc9a2d563799d59507f6acc47ed 580 SUPERFAMILY SSF52540 333 578 3.82E-98 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS02990 47dc1dc9a2d563799d59507f6acc47ed 580 Pfam PF00664 ABC transporter transmembrane region 23 295 8.3E-44 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GTHT12_RS02990 47dc1dc9a2d563799d59507f6acc47ed 580 ProSitePatterns PS00211 ABC transporters family signature. 480 494 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS02990 47dc1dc9a2d563799d59507f6acc47ed 580 SMART SM00382 368 554 4.7E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS02990 47dc1dc9a2d563799d59507f6acc47ed 580 Gene3D G3DSA:3.40.50.300 342 573 5.2E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01515 0b421f45417939ad3f5e0dd0bee3cc8d 316 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 39 169 1.8E-64 T 06-07-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 GTHT12_RS01515 0b421f45417939ad3f5e0dd0bee3cc8d 316 PIRSF PIRSF002849 2 313 1.1E-136 T 06-07-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted GTHT12_RS01515 0b421f45417939ad3f5e0dd0bee3cc8d 316 SUPERFAMILY SSF52540 10 283 7.96E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01515 0b421f45417939ad3f5e0dd0bee3cc8d 316 Gene3D G3DSA:3.40.50.300 21 185 7.0E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01515 0b421f45417939ad3f5e0dd0bee3cc8d 316 Gene3D G3DSA:1.10.8.300 200 307 1.5E-38 T 06-07-2017 GTHT12_RS06570 71242c4646138f6b679a18269abc1fb5 328 Gene3D G3DSA:3.40.50.620 15 182 8.3E-57 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS06570 71242c4646138f6b679a18269abc1fb5 328 Gene3D G3DSA:2.40.30.30 183 313 5.6E-41 T 06-07-2017 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 GTHT12_RS06570 71242c4646138f6b679a18269abc1fb5 328 Pfam PF06574 FAD synthetase 19 170 4.5E-47 T 06-07-2017 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GTHT12_RS06570 71242c4646138f6b679a18269abc1fb5 328 SMART SM00904 186 313 3.7E-62 T 06-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 GTHT12_RS06570 71242c4646138f6b679a18269abc1fb5 328 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 23 312 1.7E-90 T 06-07-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GTHT12_RS06570 71242c4646138f6b679a18269abc1fb5 328 SUPERFAMILY SSF52374 21 179 2.06E-29 T 06-07-2017 GTHT12_RS06570 71242c4646138f6b679a18269abc1fb5 328 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 23 64 4.8E-7 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 GTHT12_RS06570 71242c4646138f6b679a18269abc1fb5 328 PIRSF PIRSF004491 4 319 3.5E-104 T 06-07-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GTHT12_RS06570 71242c4646138f6b679a18269abc1fb5 328 Pfam PF01687 Riboflavin kinase 187 312 4.6E-37 T 06-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 GTHT12_RS06570 71242c4646138f6b679a18269abc1fb5 328 SUPERFAMILY SSF82114 177 314 3.05E-44 T 06-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 GTHT12_RS02740 0b7630a439278199992ee108e90af249 107 SMART SM00857 3 105 2.4E-11 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 GTHT12_RS02740 0b7630a439278199992ee108e90af249 107 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 06-07-2017 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 GTHT12_RS02740 0b7630a439278199992ee108e90af249 107 Pfam PF00239 Resolvase, N terminal domain 3 107 3.3E-17 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 GTHT12_RS02740 0b7630a439278199992ee108e90af249 107 SUPERFAMILY SSF53041 2 107 4.58E-16 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 GTHT12_RS02740 0b7630a439278199992ee108e90af249 107 Gene3D G3DSA:3.40.50.1390 3 107 4.2E-15 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 GTHT12_RS02400 c0cb283c950adfdfb04952f84e8650e8 150 Gene3D G3DSA:3.90.1720.10 27 150 3.5E-50 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain GTHT12_RS02400 c0cb283c950adfdfb04952f84e8650e8 150 Pfam PF00877 NlpC/P60 family 44 149 5.5E-35 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain GTHT12_RS02400 c0cb283c950adfdfb04952f84e8650e8 150 SUPERFAMILY SSF54001 29 150 9.16E-47 T 06-07-2017 GTHT12_RS10630 5e0967c9c53523b7a6f0aa850b088c5b 106 SUPERFAMILY SSF117916 5 99 6.54E-28 T 06-07-2017 GTHT12_RS10630 5e0967c9c53523b7a6f0aa850b088c5b 106 Pfam PF01883 Domain of unknown function DUF59 10 78 2.2E-14 T 06-07-2017 IPR002744 Domain of unknown function DUF59 GTHT12_RS02385 0bb70e1d9859f0e7c213da0dc449c46f 470 Gene3D G3DSA:3.30.465.10 97 217 9.9E-49 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 GTHT12_RS02385 0bb70e1d9859f0e7c213da0dc449c46f 470 Pfam PF01565 FAD binding domain 41 180 1.6E-45 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 GTHT12_RS02385 0bb70e1d9859f0e7c213da0dc449c46f 470 Gene3D G3DSA:3.30.43.10 4 96 1.9E-33 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 GTHT12_RS02385 0bb70e1d9859f0e7c213da0dc449c46f 470 SUPERFAMILY SSF55103 220 459 3.92E-70 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 GTHT12_RS02385 0bb70e1d9859f0e7c213da0dc449c46f 470 SUPERFAMILY SSF56176 5 217 4.11E-76 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 GTHT12_RS02385 0bb70e1d9859f0e7c213da0dc449c46f 470 TIGRFAM TIGR00387 glcD: glycolate oxidase, subunit GlcD 44 456 5.2E-184 T 06-07-2017 IPR004490 Glycolate oxidase subunit GlcD GO:0008891|GO:0009339 GTHT12_RS02385 0bb70e1d9859f0e7c213da0dc449c46f 470 Pfam PF02913 FAD linked oxidases, C-terminal domain 217 457 6.8E-75 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 GTHT12_RS02385 0bb70e1d9859f0e7c213da0dc449c46f 470 Gene3D G3DSA:1.10.45.10 418 457 1.5E-15 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 GTHT12_RS02815 33e7ec0d11c0309fbc356b7e47b8bd97 57 Gene3D G3DSA:3.30.450.20 15 50 7.0E-8 T 06-07-2017 GTHT12_RS02815 33e7ec0d11c0309fbc356b7e47b8bd97 57 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 10 46 2.3E-6 T 06-07-2017 IPR000014 PAS domain GTHT12_RS02815 33e7ec0d11c0309fbc356b7e47b8bd97 57 SUPERFAMILY SSF55785 15 51 1.15E-8 T 06-07-2017 IPR000014 PAS domain GTHT12_RS02815 33e7ec0d11c0309fbc356b7e47b8bd97 57 Pfam PF00989 PAS fold 15 47 4.1E-6 T 06-07-2017 IPR013767 PAS fold GO:0006355 GTHT12_RS00730 e56fbbc02e9e9e7ec16e42502e98da83 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00730 e56fbbc02e9e9e7ec16e42502e98da83 132 Gene3D G3DSA:3.30.1370.30 2 73 1.0E-32 T 06-07-2017 GTHT12_RS00730 e56fbbc02e9e9e7ec16e42502e98da83 132 Pfam PF00410 Ribosomal protein S8 5 132 2.7E-55 T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00730 e56fbbc02e9e9e7ec16e42502e98da83 132 SUPERFAMILY SSF56047 2 132 2.75E-51 T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00730 e56fbbc02e9e9e7ec16e42502e98da83 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 33.4 T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00730 e56fbbc02e9e9e7ec16e42502e98da83 132 Gene3D G3DSA:3.30.1490.10 76 132 1.0E-30 T 06-07-2017 GTHT12_RS04560 e21353190a0fabbe84f7d835d7f4d18f 144 SUPERFAMILY SSF55729 10 143 2.1E-40 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS04560 e21353190a0fabbe84f7d835d7f4d18f 144 Pfam PF13673 Acetyltransferase (GNAT) domain 38 143 1.1E-23 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS04560 e21353190a0fabbe84f7d835d7f4d18f 144 Gene3D G3DSA:3.40.630.30 13 143 1.5E-42 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS02305 dd7335b76cec85b72cb51e6eb93d2ef0 278 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 169 2.2E-29 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 GTHT12_RS02305 dd7335b76cec85b72cb51e6eb93d2ef0 278 Gene3D G3DSA:3.30.465.10 61 169 3.2E-20 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 GTHT12_RS02305 dd7335b76cec85b72cb51e6eb93d2ef0 278 Gene3D G3DSA:3.30.390.50 183 274 2.3E-8 T 06-07-2017 GTHT12_RS02305 dd7335b76cec85b72cb51e6eb93d2ef0 278 SUPERFAMILY SSF56176 1 169 6.82E-35 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 GTHT12_RS02305 dd7335b76cec85b72cb51e6eb93d2ef0 278 SUPERFAMILY SSF55447 178 275 9.29E-15 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal GTHT12_RS02305 dd7335b76cec85b72cb51e6eb93d2ef0 278 Gene3D G3DSA:3.30.43.10 1 56 1.6E-12 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 GTHT12_RS02305 dd7335b76cec85b72cb51e6eb93d2ef0 278 SMART SM01092 179 274 4.0E-13 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal GTHT12_RS03000 e66738ca7d66266f53b5d1faee92d730 322 Gene3D G3DSA:3.40.50.300 5 257 1.7E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03000 e66738ca7d66266f53b5d1faee92d730 322 SMART SM00382 41 233 2.1E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS03000 e66738ca7d66266f53b5d1faee92d730 322 SUPERFAMILY SSF52540 5 255 1.54E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03000 e66738ca7d66266f53b5d1faee92d730 322 Pfam PF00005 ABC transporter 33 183 1.7E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS03000 e66738ca7d66266f53b5d1faee92d730 322 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS03000 e66738ca7d66266f53b5d1faee92d730 322 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 300 2.8E-16 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 GTHT12_RS03000 e66738ca7d66266f53b5d1faee92d730 322 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 320 6.4E-28 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 GTHT12_RS02535 f836b093af7d367fe259bc26e7fb640c 199 Pfam PF16859 Bacterial transcriptional repressor C-terminal 83 192 4.7E-12 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal GTHT12_RS02535 f836b093af7d367fe259bc26e7fb640c 199 Gene3D G3DSA:1.10.357.10 81 196 8.7E-10 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 GTHT12_RS02535 f836b093af7d367fe259bc26e7fb640c 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 2.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS02535 f836b093af7d367fe259bc26e7fb640c 199 SUPERFAMILY SSF46689 9 70 4.84E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS02535 f836b093af7d367fe259bc26e7fb640c 199 SUPERFAMILY SSF48498 86 196 6.89E-7 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal GTHT12_RS02535 f836b093af7d367fe259bc26e7fb640c 199 Gene3D G3DSA:1.10.10.60 6 67 6.8E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS03145 7588d61b2e0928f6e0a7492c67b7decf 150 SUPERFAMILY SSF46785 11 141 1.73E-43 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS03145 7588d61b2e0928f6e0a7492c67b7decf 150 Pfam PF01475 Ferric uptake regulator family 18 136 6.4E-41 T 06-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 GTHT12_RS03145 7588d61b2e0928f6e0a7492c67b7decf 150 Gene3D G3DSA:1.10.10.10 10 89 5.7E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12060 0a35f6fa8e4d9208e694e0fa261c53f4 449 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 247 327 9.1E-28 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS12060 0a35f6fa8e4d9208e694e0fa261c53f4 449 PRINTS PR01703 Manganese superoxide dismutase signature 251 262 5.3E-21 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS12060 0a35f6fa8e4d9208e694e0fa261c53f4 449 PRINTS PR01703 Manganese superoxide dismutase signature 272 285 5.3E-21 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS12060 0a35f6fa8e4d9208e694e0fa261c53f4 449 PRINTS PR01703 Manganese superoxide dismutase signature 402 414 5.3E-21 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS12060 0a35f6fa8e4d9208e694e0fa261c53f4 449 PRINTS PR01703 Manganese superoxide dismutase signature 364 372 5.3E-21 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS12060 0a35f6fa8e4d9208e694e0fa261c53f4 449 PRINTS PR01703 Manganese superoxide dismutase signature 311 324 5.3E-21 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS12060 0a35f6fa8e4d9208e694e0fa261c53f4 449 SUPERFAMILY SSF54719 327 442 8.51E-43 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS12060 0a35f6fa8e4d9208e694e0fa261c53f4 449 SUPERFAMILY SSF46609 243 329 2.62E-32 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS12060 0a35f6fa8e4d9208e694e0fa261c53f4 449 Gene3D G3DSA:1.10.287.990 265 327 1.1E-21 T 06-07-2017 GTHT12_RS12060 0a35f6fa8e4d9208e694e0fa261c53f4 449 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 404 411 - T 06-07-2017 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS12060 0a35f6fa8e4d9208e694e0fa261c53f4 449 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 335 437 1.7E-35 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 GTHT12_RS10690 63c79e834260337390ae4edc95de6229 496 Gene3D G3DSA:1.20.1250.20 25 210 2.4E-16 T 06-07-2017 GTHT12_RS10690 63c79e834260337390ae4edc95de6229 496 Gene3D G3DSA:1.20.1250.20 297 486 5.2E-5 T 06-07-2017 GTHT12_RS10690 63c79e834260337390ae4edc95de6229 496 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 158 170 - T 06-07-2017 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 GTHT12_RS10690 63c79e834260337390ae4edc95de6229 496 SUPERFAMILY SSF103473 280 487 5.76E-30 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS10690 63c79e834260337390ae4edc95de6229 496 SUPERFAMILY SSF103473 15 210 5.76E-30 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS10690 63c79e834260337390ae4edc95de6229 496 Pfam PF00854 POT family 96 460 1.1E-78 T 06-07-2017 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 GTHT12_RS10690 63c79e834260337390ae4edc95de6229 496 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 17 492 1.7E-134 T 06-07-2017 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 GTHT12_RS10690 63c79e834260337390ae4edc95de6229 496 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 84 108 - T 06-07-2017 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 GTHT12_RS02960 19f4abb1160016a11b61c95766a5c470 368 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 43 176 1.2E-20 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 GTHT12_RS02960 19f4abb1160016a11b61c95766a5c470 368 SUPERFAMILY SSF55811 228 359 5.82E-28 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 GTHT12_RS02960 19f4abb1160016a11b61c95766a5c470 368 Gene3D G3DSA:1.10.1670.10 132 234 6.6E-41 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 GTHT12_RS02960 19f4abb1160016a11b61c95766a5c470 368 Gene3D G3DSA:3.90.79.10 239 361 5.1E-34 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 GTHT12_RS02960 19f4abb1160016a11b61c95766a5c470 368 SMART SM00525 199 219 2.5E-4 T 06-07-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 GTHT12_RS02960 19f4abb1160016a11b61c95766a5c470 368 Gene3D G3DSA:1.10.340.30 29 131 2.0E-43 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 GTHT12_RS02960 19f4abb1160016a11b61c95766a5c470 368 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 15 276 2.3E-108 T 06-07-2017 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 GTHT12_RS02960 19f4abb1160016a11b61c95766a5c470 368 SMART SM00478 47 198 3.6E-53 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 GTHT12_RS02960 19f4abb1160016a11b61c95766a5c470 368 Pfam PF00633 Helix-hairpin-helix motif 107 135 4.8E-7 T 06-07-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 GTHT12_RS02960 19f4abb1160016a11b61c95766a5c470 368 Pfam PF14815 NUDIX domain 242 355 6.9E-21 T 06-07-2017 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 GTHT12_RS02960 19f4abb1160016a11b61c95766a5c470 368 SUPERFAMILY SSF48150 12 230 1.38E-77 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 GTHT12_RS14020 1e67cc038c2e7eafbb46640e5d77f56f 195 Gene3D G3DSA:1.10.10.60 9 57 7.5E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS14020 1e67cc038c2e7eafbb46640e5d77f56f 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.5E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS14020 1e67cc038c2e7eafbb46640e5d77f56f 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 1.5E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS14020 1e67cc038c2e7eafbb46640e5d77f56f 195 SUPERFAMILY SSF46689 4 83 3.15E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS14020 1e67cc038c2e7eafbb46640e5d77f56f 195 SUPERFAMILY SSF48498 78 191 8.66E-32 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal GTHT12_RS14020 1e67cc038c2e7eafbb46640e5d77f56f 195 Pfam PF08359 YsiA-like protein, C-terminal region 58 190 5.5E-65 T 06-07-2017 IPR013570 Transcription regulator YsiA, C-terminal GTHT12_RS14020 1e67cc038c2e7eafbb46640e5d77f56f 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 7.0E-18 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS14020 1e67cc038c2e7eafbb46640e5d77f56f 195 Gene3D G3DSA:1.10.357.10 58 193 1.0E-48 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 GTHT12_RS13515 4c0c622e0437bbbe9e468a8c67245879 127 Pfam PF12670 Protein of unknown function (DUF3792) 6 116 9.6E-27 T 06-07-2017 IPR023804 Protein of unknown function DUF3792, transmembrane GTHT12_RS13515 4c0c622e0437bbbe9e468a8c67245879 127 TIGRFAM TIGR04086 TIGR04086_membr: putative membrane protein, TIGR04086 family 7 119 4.2E-32 T 06-07-2017 IPR023804 Protein of unknown function DUF3792, transmembrane GTHT12_RS09800 c21dcf03b8f9166dacce46ad60aa3346 445 Hamap MF_00455 Xylose isomerase [xylA]. 10 434 56.894 T 06-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 GTHT12_RS09800 c21dcf03b8f9166dacce46ad60aa3346 445 TIGRFAM TIGR02630 xylose_isom_A: xylose isomerase 3 434 4.7E-226 T 06-07-2017 IPR013452 Xylose isomerase, bacterial-type GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 GTHT12_RS09800 c21dcf03b8f9166dacce46ad60aa3346 445 Pfam PF01261 Xylose isomerase-like TIM barrel 154 282 1.1E-6 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain GTHT12_RS09800 c21dcf03b8f9166dacce46ad60aa3346 445 SUPERFAMILY SSF51658 2 436 1.52E-183 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain GTHT12_RS09800 c21dcf03b8f9166dacce46ad60aa3346 445 Gene3D G3DSA:3.20.20.150 2 436 4.0E-206 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain GTHT12_RS09800 c21dcf03b8f9166dacce46ad60aa3346 445 PRINTS PR00688 Xylose isomerase signature 331 342 1.6E-102 T 06-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 GTHT12_RS09800 c21dcf03b8f9166dacce46ad60aa3346 445 PRINTS PR00688 Xylose isomerase signature 154 173 1.6E-102 T 06-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 GTHT12_RS09800 c21dcf03b8f9166dacce46ad60aa3346 445 PRINTS PR00688 Xylose isomerase signature 90 112 1.6E-102 T 06-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 GTHT12_RS09800 c21dcf03b8f9166dacce46ad60aa3346 445 PRINTS PR00688 Xylose isomerase signature 131 151 1.6E-102 T 06-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 GTHT12_RS09800 c21dcf03b8f9166dacce46ad60aa3346 445 PRINTS PR00688 Xylose isomerase signature 205 224 1.6E-102 T 06-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 GTHT12_RS09800 c21dcf03b8f9166dacce46ad60aa3346 445 PRINTS PR00688 Xylose isomerase signature 269 296 1.6E-102 T 06-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 GTHT12_RS09800 c21dcf03b8f9166dacce46ad60aa3346 445 PRINTS PR00688 Xylose isomerase signature 178 199 1.6E-102 T 06-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 GTHT12_RS09800 c21dcf03b8f9166dacce46ad60aa3346 445 PRINTS PR00688 Xylose isomerase signature 298 309 1.6E-102 T 06-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 GTHT12_RS09800 c21dcf03b8f9166dacce46ad60aa3346 445 PRINTS PR00688 Xylose isomerase signature 227 251 1.6E-102 T 06-07-2017 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 GTHT12_RS08890 c79d28f348707217326cb1ecf0d1c6f5 487 Pfam PF07732 Multicopper oxidase 62 177 4.5E-32 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 GTHT12_RS08890 c79d28f348707217326cb1ecf0d1c6f5 487 SUPERFAMILY SSF49503 36 179 3.91E-37 T 06-07-2017 IPR008972 Cupredoxin GTHT12_RS08890 c79d28f348707217326cb1ecf0d1c6f5 487 Gene3D G3DSA:2.60.40.420 43 179 9.2E-36 T 06-07-2017 IPR008972 Cupredoxin GTHT12_RS08890 c79d28f348707217326cb1ecf0d1c6f5 487 Pfam PF07731 Multicopper oxidase 345 468 5.2E-22 T 06-07-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 GTHT12_RS08890 c79d28f348707217326cb1ecf0d1c6f5 487 Gene3D G3DSA:2.60.40.420 180 303 1.4E-31 T 06-07-2017 IPR008972 Cupredoxin GTHT12_RS08890 c79d28f348707217326cb1ecf0d1c6f5 487 SUPERFAMILY SSF49503 336 467 1.55E-26 T 06-07-2017 IPR008972 Cupredoxin GTHT12_RS08890 c79d28f348707217326cb1ecf0d1c6f5 487 ProSitePatterns PS00080 Multicopper oxidases signature 2. 450 461 - T 06-07-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 GTHT12_RS08890 c79d28f348707217326cb1ecf0d1c6f5 487 SUPERFAMILY SSF49503 181 304 1.9E-25 T 06-07-2017 IPR008972 Cupredoxin GTHT12_RS08890 c79d28f348707217326cb1ecf0d1c6f5 487 Gene3D G3DSA:2.60.40.420 326 467 1.9E-31 T 06-07-2017 IPR008972 Cupredoxin GTHT12_RS13800 f377184af6893279fe07a7367af7eab2 324 SMART SM01004 3 322 1.0E-248 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13800 f377184af6893279fe07a7367af7eab2 324 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 241 253 - T 06-07-2017 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13800 f377184af6893279fe07a7367af7eab2 324 Gene3D G3DSA:3.20.20.70 4 324 2.4E-157 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS13800 f377184af6893279fe07a7367af7eab2 324 Pfam PF00490 Delta-aminolevulinic acid dehydratase 6 321 3.6E-157 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13800 f377184af6893279fe07a7367af7eab2 324 SUPERFAMILY SSF51569 5 323 3.52E-147 T 06-07-2017 GTHT12_RS13800 f377184af6893279fe07a7367af7eab2 324 PIRSF PIRSF001415 1 324 6.6E-160 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13800 f377184af6893279fe07a7367af7eab2 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 121 135 2.0E-60 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13800 f377184af6893279fe07a7367af7eab2 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 151 170 2.0E-60 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13800 f377184af6893279fe07a7367af7eab2 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 189 208 2.0E-60 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13800 f377184af6893279fe07a7367af7eab2 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 241 257 2.0E-60 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13800 f377184af6893279fe07a7367af7eab2 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 296 315 2.0E-60 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS13800 f377184af6893279fe07a7367af7eab2 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 266 281 2.0E-60 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 GTHT12_RS10655 1535251855c8f332b2bedce66c80759a 502 Gene3D G3DSA:3.40.605.10 15 274 1.2E-109 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10655 1535251855c8f332b2bedce66c80759a 502 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 260 267 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10655 1535251855c8f332b2bedce66c80759a 502 SUPERFAMILY SSF53720 10 490 3.4E-179 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10655 1535251855c8f332b2bedce66c80759a 502 Gene3D G3DSA:3.40.309.10 275 454 3.9E-71 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 GTHT12_RS10655 1535251855c8f332b2bedce66c80759a 502 Pfam PF00171 Aldehyde dehydrogenase family 25 488 3.5E-185 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS15105 2c9a140d15a8b1e889af9e61aba4498a 198 Pfam PF13302 Acetyltransferase (GNAT) domain 10 153 9.6E-23 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS15105 2c9a140d15a8b1e889af9e61aba4498a 198 Gene3D G3DSA:3.40.630.30 5 182 4.9E-43 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS15105 2c9a140d15a8b1e889af9e61aba4498a 198 SUPERFAMILY SSF55729 4 178 3.6E-41 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS03660 7d2796c0b45328056b03b610039a02f5 278 Pfam PF13616 PPIC-type PPIASE domain 134 224 7.1E-31 T 06-07-2017 GTHT12_RS03660 7d2796c0b45328056b03b610039a02f5 278 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 162 183 - T 06-07-2017 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-936440 GTHT12_RS03660 7d2796c0b45328056b03b610039a02f5 278 SUPERFAMILY SSF109998 26 163 3.73E-21 T 06-07-2017 IPR027304 Trigger factor/SurA domain GTHT12_RS03660 7d2796c0b45328056b03b610039a02f5 278 Gene3D G3DSA:3.10.50.40 132 245 1.6E-47 T 06-07-2017 GTHT12_RS03660 7d2796c0b45328056b03b610039a02f5 278 Hamap MF_01145 Foldase protein PrsA [prsA]. 1 278 21.42 T 06-07-2017 IPR023059 Foldase protein PrsA GO:0003755 GTHT12_RS03660 7d2796c0b45328056b03b610039a02f5 278 SUPERFAMILY SSF54534 118 223 2.92E-38 T 06-07-2017 GTHT12_RS03660 7d2796c0b45328056b03b610039a02f5 278 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 25 113 8.9E-7 T 06-07-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 GTHT12_RS09525 901e5561eba888c0f69f581c51b4d748 490 Gene3D G3DSA:3.20.140.10 8 389 7.1E-135 T 06-07-2017 GTHT12_RS09525 901e5561eba888c0f69f581c51b4d748 490 SUPERFAMILY SSF51690 141 480 1.46E-132 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 GTHT12_RS09525 901e5561eba888c0f69f581c51b4d748 490 PIRSF PIRSF000484 6 482 2.5E-155 T 06-07-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 GTHT12_RS09525 901e5561eba888c0f69f581c51b4d748 490 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 159 340 3.3E-8 T 06-07-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 GTHT12_RS09525 901e5561eba888c0f69f581c51b4d748 490 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 12 466 3.0E-182 T 06-07-2017 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 GTHT12_RS09525 901e5561eba888c0f69f581c51b4d748 490 SUPERFAMILY SSF54675 7 140 1.47E-51 T 06-07-2017 GTHT12_RS12355 cffd5408de8b532b28db16f5aed2cfae 157 Gene3D G3DSA:2.40.50.180 41 76 4.1E-8 T 06-07-2017 GTHT12_RS12355 cffd5408de8b532b28db16f5aed2cfae 157 Gene3D G3DSA:2.30.30.40 77 126 8.1E-8 T 06-07-2017 GTHT12_RS12355 cffd5408de8b532b28db16f5aed2cfae 157 SUPERFAMILY SSF50341 3 139 7.72E-34 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 GTHT12_RS12355 cffd5408de8b532b28db16f5aed2cfae 157 Pfam PF01584 CheW-like domain 4 138 3.3E-32 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 GTHT12_RS12355 cffd5408de8b532b28db16f5aed2cfae 157 SMART SM00260 1 135 3.2E-26 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 GTHT12_RS14610 53bb2880a615bbfc81982c112859f705 110 SUPERFAMILY SSF52833 3 94 6.73E-7 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS14610 53bb2880a615bbfc81982c112859f705 110 Gene3D G3DSA:3.40.30.10 9 90 2.1E-4 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS14610 53bb2880a615bbfc81982c112859f705 110 Pfam PF11009 Protein of unknown function (DUF2847) 5 103 2.1E-37 T 06-07-2017 IPR022551 Protein of unknown function DUF2847 GTHT12_RS14610 53bb2880a615bbfc81982c112859f705 110 TIGRFAM TIGR04019 B_thiol_YtxJ: bacillithiol system protein YtxJ 5 104 1.5E-36 T 06-07-2017 IPR022551 Protein of unknown function DUF2847 GTHT12_RS14685 4508260b19a40d7a947edaf428e57843 313 PIRSF PIRSF012560 1 310 1.7E-125 T 06-07-2017 IPR012397 Pullulan 6-glucanohydrolase GTHT12_RS01260 6c9f190d5e8f45808643c98216b55ad4 356 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 5 142 2.8E-40 T 06-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 GTHT12_RS01260 6c9f190d5e8f45808643c98216b55ad4 356 Gene3D G3DSA:3.40.50.2000 194 337 3.6E-8 T 06-07-2017 GTHT12_RS01260 6c9f190d5e8f45808643c98216b55ad4 356 SUPERFAMILY SSF53756 3 353 1.71E-93 T 06-07-2017 GTHT12_RS01260 6c9f190d5e8f45808643c98216b55ad4 356 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 190 338 1.5E-29 T 06-07-2017 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 GTHT12_RS01260 6c9f190d5e8f45808643c98216b55ad4 356 Gene3D G3DSA:3.40.50.2000 3 193 3.4E-63 T 06-07-2017 GTHT12_RS01260 6c9f190d5e8f45808643c98216b55ad4 356 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 5 355 28.914 T 06-07-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 GTHT12_RS01260 6c9f190d5e8f45808643c98216b55ad4 356 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 3 348 3.6E-77 T 06-07-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 GTHT12_RS12855 3125d6485321579e054ea02f5d29d2e1 258 Pfam PF01940 Integral membrane protein DUF92 11 246 3.1E-59 T 06-07-2017 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 GTHT12_RS17765 c73d3376f9e3cb6a664e587c48aad1dc 324 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 20 320 1.3E-123 T 06-07-2017 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 GTHT12_RS17765 c73d3376f9e3cb6a664e587c48aad1dc 324 Gene3D G3DSA:3.40.50.10750 137 296 4.9E-71 T 06-07-2017 GTHT12_RS17765 c73d3376f9e3cb6a664e587c48aad1dc 324 PIRSF PIRSF000428 2 324 8.3E-109 T 06-07-2017 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 GTHT12_RS17765 c73d3376f9e3cb6a664e587c48aad1dc 324 SUPERFAMILY SSF53659 7 322 3.87E-95 T 06-07-2017 GTHT12_RS17765 c73d3376f9e3cb6a664e587c48aad1dc 324 Pfam PF01515 Phosphate acetyl/butaryl transferase 8 320 2.9E-127 T 06-07-2017 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 GTHT12_RS05145 803379dab4da4d2b6d2e7d1288e6aa2c 503 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 21 480 9.0E-157 T 06-07-2017 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 GTHT12_RS05145 803379dab4da4d2b6d2e7d1288e6aa2c 503 PIRSF PIRSF005690 9 495 3.4E-139 T 06-07-2017 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 GTHT12_RS09120 8615e14db6dd8adec9212f40d383ebc7 290 Gene3D G3DSA:2.30.140.10 18 70 1.4E-21 T 06-07-2017 GTHT12_RS09120 8615e14db6dd8adec9212f40d383ebc7 290 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 95 108 - T 06-07-2017 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 GTHT12_RS09120 8615e14db6dd8adec9212f40d383ebc7 290 Gene3D G3DSA:3.40.50.150 71 289 4.7E-76 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS09120 8615e14db6dd8adec9212f40d383ebc7 290 Pfam PF01564 Spermine/spermidine synthase 20 252 1.0E-73 T 06-07-2017 GTHT12_RS09120 8615e14db6dd8adec9212f40d383ebc7 290 SUPERFAMILY SSF53335 17 289 1.43E-83 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS09120 8615e14db6dd8adec9212f40d383ebc7 290 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 19 289 36.92 T 06-07-2017 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 GTHT12_RS09120 8615e14db6dd8adec9212f40d383ebc7 290 TIGRFAM TIGR00417 speE: spermidine synthase 20 283 1.2E-87 T 06-07-2017 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 GTHT12_RS04525 8ea2c3eb23b98b706fc808f224e612ce 118 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 5 118 4.7E-52 T 06-07-2017 IPR014204 Sporulation stage V, protein AE GTHT12_RS04525 8ea2c3eb23b98b706fc808f224e612ce 118 Pfam PF03862 SpoVA protein 5 112 7.8E-42 T 06-07-2017 IPR005562 SpoVA GTHT12_RS13750 dfe5b2b4c346f107fd9a605321530039 191 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site GTHT12_RS13750 dfe5b2b4c346f107fd9a605321530039 191 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 30 3.3E-4 T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site GTHT12_RS11160 2528ed233647b8e3ee8359c1d1ce3cc3 435 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 219 425 1.0E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS11160 2528ed233647b8e3ee8359c1d1ce3cc3 435 Gene3D G3DSA:1.10.3720.10 1 51 3.3E-72 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS11160 2528ed233647b8e3ee8359c1d1ce3cc3 435 Gene3D G3DSA:1.10.3720.10 184 419 3.3E-72 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS11160 2528ed233647b8e3ee8359c1d1ce3cc3 435 SUPERFAMILY SSF161098 188 417 3.53E-65 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS10335 2d7ed81f6f8d0fe258089bac42d24159 161 SUPERFAMILY SSF55729 10 127 9.61E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS10335 2d7ed81f6f8d0fe258089bac42d24159 161 Gene3D G3DSA:3.40.630.30 12 130 2.1E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS10335 2d7ed81f6f8d0fe258089bac42d24159 161 Pfam PF00583 Acetyltransferase (GNAT) family 46 119 1.9E-12 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS00590 52374001b4fe5895f2cc9c399c6530d7 177 SUPERFAMILY SSF50104 121 177 7.74E-19 T 06-07-2017 IPR008991 Translation protein SH3-like domain GTHT12_RS00590 52374001b4fe5895f2cc9c399c6530d7 177 Gene3D G3DSA:3.30.70.940 2 114 6.3E-51 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 GTHT12_RS00590 52374001b4fe5895f2cc9c399c6530d7 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 177 7.7E-67 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 GTHT12_RS00590 52374001b4fe5895f2cc9c399c6530d7 177 Pfam PF00467 KOW motif 127 155 1.0E-6 T 06-07-2017 IPR005824 KOW GTHT12_RS00590 52374001b4fe5895f2cc9c399c6530d7 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 5.1E-19 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 GTHT12_RS00590 52374001b4fe5895f2cc9c399c6530d7 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 5.1E-19 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 GTHT12_RS00590 52374001b4fe5895f2cc9c399c6530d7 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 5.1E-19 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 GTHT12_RS00590 52374001b4fe5895f2cc9c399c6530d7 177 SMART SM00738 2 113 2.2E-56 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 GTHT12_RS00590 52374001b4fe5895f2cc9c399c6530d7 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 29.377 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 GTHT12_RS00590 52374001b4fe5895f2cc9c399c6530d7 177 Pfam PF02357 Transcription termination factor nusG 3 109 2.6E-30 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 GTHT12_RS00590 52374001b4fe5895f2cc9c399c6530d7 177 SUPERFAMILY SSF82679 2 114 5.89E-42 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 GTHT12_RS00590 52374001b4fe5895f2cc9c399c6530d7 177 SMART SM00739 123 150 6.6E-6 T 06-07-2017 IPR005824 KOW GTHT12_RS00590 52374001b4fe5895f2cc9c399c6530d7 177 Gene3D G3DSA:2.30.30.30 119 177 7.8E-29 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 GTHT12_RS17650 60218b0889df7e6a4f737a3114e0f70e 380 Gene3D G3DSA:2.40.110.10 120 217 1.0E-44 T 06-07-2017 GTHT12_RS17650 60218b0889df7e6a4f737a3114e0f70e 380 SUPERFAMILY SSF47203 227 379 1.93E-62 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS17650 60218b0889df7e6a4f737a3114e0f70e 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 GTHT12_RS17650 60218b0889df7e6a4f737a3114e0f70e 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 GTHT12_RS17650 60218b0889df7e6a4f737a3114e0f70e 380 SUPERFAMILY SSF56645 2 240 2.09E-90 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 GTHT12_RS17650 60218b0889df7e6a4f737a3114e0f70e 380 PIRSF PIRSF016578 4 369 3.0E-20 T 06-07-2017 GTHT12_RS17650 60218b0889df7e6a4f737a3114e0f70e 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 1.1E-54 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS17650 60218b0889df7e6a4f737a3114e0f70e 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 3.6E-40 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS17650 60218b0889df7e6a4f737a3114e0f70e 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 216 1.5E-28 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 GTHT12_RS17650 60218b0889df7e6a4f737a3114e0f70e 380 Gene3D G3DSA:1.10.540.10 2 118 2.3E-43 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS17650 60218b0889df7e6a4f737a3114e0f70e 380 Gene3D G3DSA:1.20.140.10 218 379 7.6E-75 T 06-07-2017 GTHT12_RS13325 dd1e213b854f603ca9cc778348370618 588 Gene3D G3DSA:3.40.710.10 245 584 4.1E-65 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS13325 dd1e213b854f603ca9cc778348370618 588 SUPERFAMILY SSF56519 47 232 3.66E-21 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 GTHT12_RS13325 dd1e213b854f603ca9cc778348370618 588 Gene3D G3DSA:3.90.1310.10 126 244 2.6E-9 T 06-07-2017 GTHT12_RS13325 dd1e213b854f603ca9cc778348370618 588 Pfam PF00905 Penicillin binding protein transpeptidase domain 260 574 3.7E-48 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 GTHT12_RS13325 dd1e213b854f603ca9cc778348370618 588 SUPERFAMILY SSF56601 186 393 3.76E-64 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS13325 dd1e213b854f603ca9cc778348370618 588 SUPERFAMILY SSF56601 427 581 3.76E-64 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS01780 80479ead84c80bbc1448fde32e6fb372 229 Pfam PF00005 ABC transporter 22 158 8.2E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS01780 80479ead84c80bbc1448fde32e6fb372 229 SUPERFAMILY SSF52540 4 216 4.64E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01780 80479ead84c80bbc1448fde32e6fb372 229 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS01780 80479ead84c80bbc1448fde32e6fb372 229 Gene3D G3DSA:3.40.50.300 2 216 1.6E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01780 80479ead84c80bbc1448fde32e6fb372 229 SMART SM00382 30 223 9.9E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS01780 80479ead84c80bbc1448fde32e6fb372 229 TIGRFAM TIGR03740 galliderm_ABC: lantibiotic protection ABC transporter, ATP-binding subunit 6 227 1.1E-118 T 06-07-2017 IPR022501 Gallidermin ABC transporter, ATP-binding subunit GTHT12_RS14290 ca033c584a1101e925f84dbe295c0927 315 Pfam PF02272 DHHA1 domain 253 308 3.5E-9 T 06-07-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 GTHT12_RS14290 ca033c584a1101e925f84dbe295c0927 315 SUPERFAMILY SSF64182 16 304 4.32E-70 T 06-07-2017 GTHT12_RS14290 ca033c584a1101e925f84dbe295c0927 315 Pfam PF01368 DHH family 18 156 1.0E-13 T 06-07-2017 IPR001667 DDH domain GTHT12_RS14290 ca033c584a1101e925f84dbe295c0927 315 Gene3D G3DSA:3.90.1640.10 16 192 3.5E-27 T 06-07-2017 GTHT12_RS13485 5c5fed886b78cafe6463df346dcd2359 170 Pfam PF00156 Phosphoribosyl transferase domain 28 149 6.5E-16 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 GTHT12_RS13485 5c5fed886b78cafe6463df346dcd2359 170 SUPERFAMILY SSF53271 2 164 7.38E-53 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS13485 5c5fed886b78cafe6463df346dcd2359 170 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 3 169 4.7E-72 T 06-07-2017 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|Reactome: R-HSA-74217 GTHT12_RS13485 5c5fed886b78cafe6463df346dcd2359 170 Gene3D G3DSA:3.40.50.2020 2 169 4.1E-68 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS13485 5c5fed886b78cafe6463df346dcd2359 170 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 39.373 T 06-07-2017 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|Reactome: R-HSA-74217 GTHT12_RS08455 03bccd96030d63e14d43a823eea59169 318 Gene3D G3DSA:3.60.15.10 23 242 5.1E-43 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS08455 03bccd96030d63e14d43a823eea59169 318 SMART SM00849 23 228 2.0E-28 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS08455 03bccd96030d63e14d43a823eea59169 318 Pfam PF00753 Metallo-beta-lactamase superfamily 28 228 4.7E-27 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS08455 03bccd96030d63e14d43a823eea59169 318 SUPERFAMILY SSF56281 13 258 9.17E-52 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS04145 d73be73e69a9f8836ecb28d8429346e6 220 SUPERFAMILY SSF161098 3 215 1.15E-51 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS04145 d73be73e69a9f8836ecb28d8429346e6 220 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 26 213 3.4E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS04145 d73be73e69a9f8836ecb28d8429346e6 220 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 9 215 4.9E-73 T 06-07-2017 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 GTHT12_RS04145 d73be73e69a9f8836ecb28d8429346e6 220 Gene3D G3DSA:1.10.3720.10 3 217 8.7E-48 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS01725 b49cce53c0a66e6ee0037d82142e449f 476 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 474 40.209 T 06-07-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 GTHT12_RS01725 b49cce53c0a66e6ee0037d82142e449f 476 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 142 156 - T 06-07-2017 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 GTHT12_RS01725 b49cce53c0a66e6ee0037d82142e449f 476 SUPERFAMILY SSF89095 295 401 7.5E-39 T 06-07-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 GTHT12_RS01725 b49cce53c0a66e6ee0037d82142e449f 476 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 473 9.1E-188 T 06-07-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 GTHT12_RS01725 b49cce53c0a66e6ee0037d82142e449f 476 Pfam PF02934 GatB/GatE catalytic domain 5 286 2.6E-114 T 06-07-2017 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 GTHT12_RS01725 b49cce53c0a66e6ee0037d82142e449f 476 Pfam PF02637 GatB domain 326 473 8.1E-61 T 06-07-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 GTHT12_RS01725 b49cce53c0a66e6ee0037d82142e449f 476 SUPERFAMILY SSF55931 4 294 5.36E-124 T 06-07-2017 GTHT12_RS01725 b49cce53c0a66e6ee0037d82142e449f 476 SMART SM00845 326 473 5.9E-86 T 06-07-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 GTHT12_RS02890 dd379ca6d6088cd8508236aba6773fe3 60 ProDom PD053407 YFHD 1 42 3.0E-15 T 06-07-2017 GTHT12_RS02890 dd379ca6d6088cd8508236aba6773fe3 60 Pfam PF14151 YfhD-like protein 1 58 3.1E-27 T 06-07-2017 IPR025435 YfhD-like protein GTHT12_RS08255 58d46552c55323f2e2e48d51766a68f9 519 SUPERFAMILY SSF52096 10 259 2.49E-68 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS08255 58d46552c55323f2e2e48d51766a68f9 519 Pfam PF01039 Carboxyl transferase domain 36 516 9.4E-162 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GTHT12_RS08255 58d46552c55323f2e2e48d51766a68f9 519 Gene3D G3DSA:3.90.226.10 254 518 3.0E-80 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS08255 58d46552c55323f2e2e48d51766a68f9 519 Gene3D G3DSA:3.90.226.10 15 253 1.1E-66 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS08255 58d46552c55323f2e2e48d51766a68f9 519 SUPERFAMILY SSF52096 221 499 3.42E-82 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS03295 a4ee8fcc56b55f0ab9fa7a99a6ff01de 157 PIRSF PIRSF029256 2 157 1.5E-66 T 06-07-2017 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 GTHT12_RS03295 a4ee8fcc56b55f0ab9fa7a99a6ff01de 157 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 3 156 5.7E-64 T 06-07-2017 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 GTHT12_RS03295 a4ee8fcc56b55f0ab9fa7a99a6ff01de 157 Pfam PF00588 SpoU rRNA Methylase family 3 145 2.2E-34 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 GTHT12_RS03295 a4ee8fcc56b55f0ab9fa7a99a6ff01de 157 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 3 154 34.652 T 06-07-2017 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 GTHT12_RS03295 a4ee8fcc56b55f0ab9fa7a99a6ff01de 157 SUPERFAMILY SSF75217 2 155 4.84E-45 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases GTHT12_RS03295 a4ee8fcc56b55f0ab9fa7a99a6ff01de 157 Gene3D G3DSA:3.40.1280.10 2 156 9.8E-64 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal GTHT12_RS08385 d7d8d8790dfc8745df533ce6b00da59a 599 SUPERFAMILY SSF52540 348 591 5.97E-92 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08385 d7d8d8790dfc8745df533ce6b00da59a 599 Pfam PF00005 ABC transporter 374 521 3.0E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS08385 d7d8d8790dfc8745df533ce6b00da59a 599 SUPERFAMILY SSF90123 26 341 3.27E-84 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GTHT12_RS08385 d7d8d8790dfc8745df533ce6b00da59a 599 SMART SM00382 381 573 4.8E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS08385 d7d8d8790dfc8745df533ce6b00da59a 599 Pfam PF00664 ABC transporter transmembrane region 41 310 8.5E-61 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GTHT12_RS08385 d7d8d8790dfc8745df533ce6b00da59a 599 Gene3D G3DSA:1.20.1560.10 26 341 4.5E-87 T 06-07-2017 GTHT12_RS08385 d7d8d8790dfc8745df533ce6b00da59a 599 Gene3D G3DSA:3.40.50.300 355 585 2.2E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08385 d7d8d8790dfc8745df533ce6b00da59a 599 ProSitePatterns PS00211 ABC transporters family signature. 493 507 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS07885 666ea5079dc293cef00c09b04ef66984 727 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 4 721 0.0 T 06-07-2017 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 GTHT12_RS07885 666ea5079dc293cef00c09b04ef66984 727 Gene3D G3DSA:2.170.170.11 135 263 2.2E-71 T 06-07-2017 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 GTHT12_RS07885 666ea5079dc293cef00c09b04ef66984 727 Gene3D G3DSA:2.170.170.11 297 334 2.2E-71 T 06-07-2017 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 GTHT12_RS07885 666ea5079dc293cef00c09b04ef66984 727 Hamap MF_00641 Malate synthase G [glcB]. 1 727 396.85 T 06-07-2017 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 GTHT12_RS07885 666ea5079dc293cef00c09b04ef66984 727 Pfam PF01274 Malate synthase 18 696 5.1E-183 T 06-07-2017 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 GTHT12_RS07885 666ea5079dc293cef00c09b04ef66984 727 Gene3D G3DSA:1.10.1860.10 1 87 4.9E-33 T 06-07-2017 GTHT12_RS07885 666ea5079dc293cef00c09b04ef66984 727 Gene3D G3DSA:3.20.20.360 335 586 1.7E-141 T 06-07-2017 GTHT12_RS07885 666ea5079dc293cef00c09b04ef66984 727 Gene3D G3DSA:3.20.20.360 88 134 1.7E-141 T 06-07-2017 GTHT12_RS07885 666ea5079dc293cef00c09b04ef66984 727 Gene3D G3DSA:3.20.20.360 265 295 1.7E-141 T 06-07-2017 GTHT12_RS07885 666ea5079dc293cef00c09b04ef66984 727 SUPERFAMILY SSF51645 3 721 0.0 T 06-07-2017 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 GTHT12_RS07885 666ea5079dc293cef00c09b04ef66984 727 Gene3D G3DSA:1.20.1220.12 589 722 7.1E-77 T 06-07-2017 GTHT12_RS10245 f47751ccb73e10310f80afa1002ec8da 435 SUPERFAMILY SSF51735 3 160 8.82E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS10245 f47751ccb73e10310f80afa1002ec8da 435 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 128 1.7E-18 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 GTHT12_RS10245 f47751ccb73e10310f80afa1002ec8da 435 Gene3D G3DSA:3.30.360.10 138 218 1.5E-52 T 06-07-2017 GTHT12_RS10245 f47751ccb73e10310f80afa1002ec8da 435 Gene3D G3DSA:3.30.360.10 284 330 1.5E-52 T 06-07-2017 GTHT12_RS10245 f47751ccb73e10310f80afa1002ec8da 435 Gene3D G3DSA:3.30.360.10 364 422 1.5E-52 T 06-07-2017 GTHT12_RS10245 f47751ccb73e10310f80afa1002ec8da 435 Gene3D G3DSA:3.40.50.720 3 137 6.9E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS10245 f47751ccb73e10310f80afa1002ec8da 435 SUPERFAMILY SSF55347 134 219 2.62E-29 T 06-07-2017 GTHT12_RS10245 f47751ccb73e10310f80afa1002ec8da 435 SUPERFAMILY SSF55347 283 349 2.62E-29 T 06-07-2017 GTHT12_RS10245 f47751ccb73e10310f80afa1002ec8da 435 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 141 238 2.8E-21 T 06-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 GTHT12_RS14190 3356f08d3baf57225e149c8d037132e3 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 2.0E-41 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS14190 3356f08d3baf57225e149c8d037132e3 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 2.0E-41 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS14190 3356f08d3baf57225e149c8d037132e3 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 2.0E-41 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS14190 3356f08d3baf57225e149c8d037132e3 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 2.0E-41 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS14190 3356f08d3baf57225e149c8d037132e3 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 2.0E-41 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS14190 3356f08d3baf57225e149c8d037132e3 342 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 2.1E-133 T 06-07-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS14190 3356f08d3baf57225e149c8d037132e3 342 PIRSF PIRSF000149 1 335 2.7E-139 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS14190 3356f08d3baf57225e149c8d037132e3 342 Gene3D G3DSA:3.40.50.720 1 160 1.5E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS14190 3356f08d3baf57225e149c8d037132e3 342 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 06-07-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS14190 3356f08d3baf57225e149c8d037132e3 342 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 4 152 1.3E-58 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS14190 3356f08d3baf57225e149c8d037132e3 342 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 6.4E-69 T 06-07-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS14190 3356f08d3baf57225e149c8d037132e3 342 SMART SM00846 3 152 1.4E-89 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS14190 3356f08d3baf57225e149c8d037132e3 342 SUPERFAMILY SSF55347 152 314 2.02E-73 T 06-07-2017 GTHT12_RS14190 3356f08d3baf57225e149c8d037132e3 342 Gene3D G3DSA:3.30.360.10 161 315 2.7E-77 T 06-07-2017 GTHT12_RS14190 3356f08d3baf57225e149c8d037132e3 342 SUPERFAMILY SSF51735 1 179 4.25E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS09475 1bb383c47a79302ff6050acadc51648c 97 Hamap MF_00330 Cobalt transport protein CbiN [cbiN]. 1 97 43.486 T 06-07-2017 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 GTHT12_RS09475 1bb383c47a79302ff6050acadc51648c 97 Pfam PF02553 Cobalt transport protein component CbiN 6 70 2.1E-28 T 06-07-2017 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 GTHT12_RS10380 11353f1b5480ee10b9d6c46b6a43ff42 342 PIRSF PIRSF017082 1 342 9.0E-110 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 GTHT12_RS10380 11353f1b5480ee10b9d6c46b6a43ff42 342 SUPERFAMILY SSF53850 43 303 1.87E-13 T 06-07-2017 GTHT12_RS10380 11353f1b5480ee10b9d6c46b6a43ff42 342 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 62 339 5.3E-36 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 GTHT12_RS10380 11353f1b5480ee10b9d6c46b6a43ff42 342 Gene3D G3DSA:3.40.190.10 142 266 1.2E-7 T 06-07-2017 GTHT12_RS12010 cf89aeda27b28fd0ab3d81de47bad3aa 405 Gene3D G3DSA:2.30.40.10 342 375 1.6E-11 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS12010 cf89aeda27b28fd0ab3d81de47bad3aa 405 Gene3D G3DSA:2.30.40.10 2 60 2.0E-10 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS12010 cf89aeda27b28fd0ab3d81de47bad3aa 405 Gene3D G3DSA:3.20.20.140 61 341 2.8E-110 T 06-07-2017 GTHT12_RS12010 cf89aeda27b28fd0ab3d81de47bad3aa 405 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 4 384 5.5E-123 T 06-07-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 GTHT12_RS12010 cf89aeda27b28fd0ab3d81de47bad3aa 405 SUPERFAMILY SSF51338 358 390 1.76E-15 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS12010 cf89aeda27b28fd0ab3d81de47bad3aa 405 SUPERFAMILY SSF51338 4 58 1.76E-15 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 GTHT12_RS12010 cf89aeda27b28fd0ab3d81de47bad3aa 405 PIRSF PIRSF038994 2 391 2.2E-139 T 06-07-2017 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 GTHT12_RS12010 cf89aeda27b28fd0ab3d81de47bad3aa 405 SUPERFAMILY SSF51556 59 358 2.11E-104 T 06-07-2017 IPR032466 Metal-dependent hydrolase GTHT12_RS12010 cf89aeda27b28fd0ab3d81de47bad3aa 405 Pfam PF01979 Amidohydrolase family 56 384 8.2E-31 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 GTHT12_RS14985 ce35736dce7bd226af559f65dfc9ad49 120 SUPERFAMILY SSF55729 2 114 7.55E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS14985 ce35736dce7bd226af559f65dfc9ad49 120 Gene3D G3DSA:3.40.630.30 2 115 1.4E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS14985 ce35736dce7bd226af559f65dfc9ad49 120 Pfam PF00583 Acetyltransferase (GNAT) family 18 90 7.7E-11 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS02525 996a658916801ea788108bc0ddc5e429 288 SUPERFAMILY SSF48150 107 286 7.69E-42 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 GTHT12_RS02525 996a658916801ea788108bc0ddc5e429 288 Gene3D G3DSA:1.10.340.30 121 235 1.7E-30 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 GTHT12_RS02525 996a658916801ea788108bc0ddc5e429 288 Gene3D G3DSA:1.10.1670.10 236 287 1.8E-16 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 GTHT12_RS02525 996a658916801ea788108bc0ddc5e429 288 SMART SM00478 128 288 7.3E-29 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 GTHT12_RS02525 996a658916801ea788108bc0ddc5e429 288 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 126 273 3.6E-19 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 GTHT12_RS14140 1148c05fe23e5dfa9ec51a45b5d481f3 119 SUPERFAMILY SSF74731 2 116 3.66E-51 T 06-07-2017 GTHT12_RS14140 1148c05fe23e5dfa9ec51a45b5d481f3 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.6E-41 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS14140 1148c05fe23e5dfa9ec51a45b5d481f3 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.6E-41 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS14140 1148c05fe23e5dfa9ec51a45b5d481f3 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.6E-41 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS14140 1148c05fe23e5dfa9ec51a45b5d481f3 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 23 72 6.0E-14 T 06-07-2017 GTHT12_RS14140 1148c05fe23e5dfa9ec51a45b5d481f3 119 Pfam PF00453 Ribosomal protein L20 3 109 8.7E-51 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS14140 1148c05fe23e5dfa9ec51a45b5d481f3 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 113 9.0E-52 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS14140 1148c05fe23e5dfa9ec51a45b5d481f3 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS14140 1148c05fe23e5dfa9ec51a45b5d481f3 119 Gene3D G3DSA:1.10.1900.20 55 117 1.1E-31 T 06-07-2017 GTHT12_RS14140 1148c05fe23e5dfa9ec51a45b5d481f3 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.878 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS06255 6edf885797035bb692770309c7d1e116 286 PIRSF PIRSF006230 1 285 1.6E-104 T 06-07-2017 IPR016478 GTPase, MTG1 GTHT12_RS06255 6edf885797035bb692770309c7d1e116 286 Gene3D G3DSA:3.40.50.300 16 179 4.5E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06255 6edf885797035bb692770309c7d1e116 286 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 4 280 4.1E-117 T 06-07-2017 IPR019991 GTP-binding protein, ribosome biogenesis GTHT12_RS06255 6edf885797035bb692770309c7d1e116 286 Pfam PF01926 50S ribosome-binding GTPase 125 206 3.6E-17 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS06255 6edf885797035bb692770309c7d1e116 286 Gene3D G3DSA:1.10.1580.10 182 274 6.4E-33 T 06-07-2017 IPR023179 GTP-binding protein, orthogonal bundle domain GTHT12_RS06255 6edf885797035bb692770309c7d1e116 286 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 125 145 9.6E-6 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS06255 6edf885797035bb692770309c7d1e116 286 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 171 186 9.6E-6 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS06255 6edf885797035bb692770309c7d1e116 286 SUPERFAMILY SSF52540 10 262 1.15E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00100 a30aeaa239e986554debfc37d2faede7 161 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 9 150 47.645 T 06-07-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 GTHT12_RS00100 a30aeaa239e986554debfc37d2faede7 161 SUPERFAMILY SSF53927 2 154 6.36E-56 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 GTHT12_RS00100 a30aeaa239e986554debfc37d2faede7 161 Gene3D G3DSA:3.40.140.10 2 148 1.6E-61 T 06-07-2017 GTHT12_RS00100 a30aeaa239e986554debfc37d2faede7 161 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 54 91 - T 06-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 GTHT12_RS00100 a30aeaa239e986554debfc37d2faede7 161 Pfam PF14437 MafB19-like deaminase 4 150 1.4E-43 T 06-07-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 GTHT12_RS10640 96782fc17d25b488c3b9b95fd1fc55c7 324 SUPERFAMILY SSF56281 4 313 1.83E-68 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS10640 96782fc17d25b488c3b9b95fd1fc55c7 324 Gene3D G3DSA:3.60.15.10 145 265 9.2E-48 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS10640 96782fc17d25b488c3b9b95fd1fc55c7 324 Gene3D G3DSA:3.60.15.10 4 108 9.2E-48 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS10640 96782fc17d25b488c3b9b95fd1fc55c7 324 Pfam PF00753 Metallo-beta-lactamase superfamily 27 238 9.1E-28 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS10640 96782fc17d25b488c3b9b95fd1fc55c7 324 SMART SM00849 26 238 2.0E-20 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS16640 1742d604eef72331a2d1814a5dc8d257 280 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 17 280 39.443 T 06-07-2017 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 GTHT12_RS16640 1742d604eef72331a2d1814a5dc8d257 280 SUPERFAMILY SSF140959 23 280 4.19E-100 T 06-07-2017 GTHT12_RS16640 1742d604eef72331a2d1814a5dc8d257 280 Pfam PF03301 Tryptophan 2,3-dioxygenase 15 279 4.9E-64 T 06-07-2017 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 GTHT12_RS16640 1742d604eef72331a2d1814a5dc8d257 280 TIGRFAM TIGR03036 trp_2_3_diox: tryptophan 2,3-dioxygenase 17 280 1.3E-123 T 06-07-2017 IPR017485 Tryptophan 2,3-dioxygenase, bacterial GO:0004833|GO:0019441 KEGG: 00380+1.13.11.11 GTHT12_RS01790 829848bde76dbc8e0b0ee6c819dbb0d8 377 Pfam PF00005 ABC transporter 18 164 9.3E-37 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS01790 829848bde76dbc8e0b0ee6c819dbb0d8 377 Gene3D G3DSA:3.20.20.70 247 370 2.0E-26 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS01790 829848bde76dbc8e0b0ee6c819dbb0d8 377 SMART SM00382 27 214 3.8E-22 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS01790 829848bde76dbc8e0b0ee6c819dbb0d8 377 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 16 369 4.0E-130 T 06-07-2017 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 GTHT12_RS01790 829848bde76dbc8e0b0ee6c819dbb0d8 377 SMART SM00116 322 369 3.6E-5 T 06-07-2017 IPR000644 CBS domain GTHT12_RS01790 829848bde76dbc8e0b0ee6c819dbb0d8 377 SMART SM00116 261 309 2.8E-7 T 06-07-2017 IPR000644 CBS domain GTHT12_RS01790 829848bde76dbc8e0b0ee6c819dbb0d8 377 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS01790 829848bde76dbc8e0b0ee6c819dbb0d8 377 SUPERFAMILY SSF54631 253 371 1.39E-26 T 06-07-2017 GTHT12_RS01790 829848bde76dbc8e0b0ee6c819dbb0d8 377 SUPERFAMILY SSF52540 1 241 7.34E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01790 829848bde76dbc8e0b0ee6c819dbb0d8 377 Pfam PF00571 CBS domain 316 369 8.1E-5 T 06-07-2017 IPR000644 CBS domain GTHT12_RS01790 829848bde76dbc8e0b0ee6c819dbb0d8 377 Pfam PF00571 CBS domain 254 304 7.6E-9 T 06-07-2017 IPR000644 CBS domain GTHT12_RS01790 829848bde76dbc8e0b0ee6c819dbb0d8 377 Gene3D G3DSA:3.40.50.300 1 237 2.7E-88 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11910 71d5e36d0c759eb4d41ca3bdbecec61a 270 Gene3D G3DSA:3.20.20.140 4 263 3.7E-28 T 06-07-2017 GTHT12_RS11910 71d5e36d0c759eb4d41ca3bdbecec61a 270 SUPERFAMILY SSF89550 1 263 5.62E-39 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 GTHT12_RS11910 71d5e36d0c759eb4d41ca3bdbecec61a 270 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 4 245 1.6E-36 T 06-07-2017 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 GTHT12_RS07065 f6c5009fca1be90f2da859e066380bca 322 PIRSF PIRSF036979 23 318 7.6E-32 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 GTHT12_RS07065 f6c5009fca1be90f2da859e066380bca 322 TIGRFAM TIGR01227 hutG: formimidoylglutamase 10 312 6.8E-87 T 06-07-2017 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 GTHT12_RS07065 f6c5009fca1be90f2da859e066380bca 322 Hamap MF_00737 Formimidoylglutamase [hutG]. 5 313 38.487 T 06-07-2017 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 GTHT12_RS07065 f6c5009fca1be90f2da859e066380bca 322 Gene3D G3DSA:3.40.800.10 2 315 4.5E-92 T 06-07-2017 IPR023696 Ureohydrolase domain GTHT12_RS07065 f6c5009fca1be90f2da859e066380bca 322 Pfam PF00491 Arginase family 45 312 8.6E-57 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 GTHT12_RS07065 f6c5009fca1be90f2da859e066380bca 322 SUPERFAMILY SSF52768 9 314 4.14E-76 T 06-07-2017 GTHT12_RS17555 cff0b5089a66547cca55f2d2b029bd81 345 PIRSF PIRSF004930 1 345 1.2E-133 T 06-07-2017 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 GTHT12_RS17555 cff0b5089a66547cca55f2d2b029bd81 345 Pfam PF01300 Telomere recombination 27 203 7.2E-61 T 06-07-2017 IPR006070 YrdC-like domain GO:0003725 GTHT12_RS17555 cff0b5089a66547cca55f2d2b029bd81 345 Gene3D G3DSA:3.90.870.10 18 210 5.7E-82 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain GTHT12_RS17555 cff0b5089a66547cca55f2d2b029bd81 345 SUPERFAMILY SSF55821 20 209 2.78E-68 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain GTHT12_RS17555 cff0b5089a66547cca55f2d2b029bd81 345 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 19 213 6.6E-63 T 06-07-2017 IPR006070 YrdC-like domain GO:0003725 GTHT12_RS17555 cff0b5089a66547cca55f2d2b029bd81 345 Pfam PF03481 Putative GTP-binding controlling metal-binding 205 339 9.7E-29 T 06-07-2017 IPR005145 Putative GTP-binding controlling metal-binding domain GTHT12_RS07725 6b5aa47e0afa410e2683f5c47f06e9f5 256 Pfam PF03746 LamB/YcsF family 4 241 6.0E-102 T 06-07-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF GTHT12_RS07725 6b5aa47e0afa410e2683f5c47f06e9f5 256 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 245 46.962 T 06-07-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF GTHT12_RS07725 6b5aa47e0afa410e2683f5c47f06e9f5 256 SUPERFAMILY SSF88713 3 250 2.59E-99 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 GTHT12_RS09980 e31d69913e6558305bbac462f3404858 496 Pfam PF02610 L-arabinose isomerase 6 357 1.6E-184 T 06-07-2017 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 GTHT12_RS09980 e31d69913e6558305bbac462f3404858 496 SUPERFAMILY SSF50443 327 494 1.33E-76 T 06-07-2017 IPR004216 L-fucose/L-arabinose isomerase, C-terminal GTHT12_RS09980 e31d69913e6558305bbac462f3404858 496 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 1 304 2.0E-172 T 06-07-2017 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 GTHT12_RS09980 e31d69913e6558305bbac462f3404858 496 PIRSF PIRSF001478 1 496 1.9E-266 T 06-07-2017 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 GTHT12_RS09980 e31d69913e6558305bbac462f3404858 496 Hamap MF_00519 L-arabinose isomerase [araA]. 1 474 68.158 T 06-07-2017 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 GTHT12_RS09980 e31d69913e6558305bbac462f3404858 496 SUPERFAMILY SSF53743 1 326 5.49E-128 T 06-07-2017 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 GTHT12_RS09980 e31d69913e6558305bbac462f3404858 496 Pfam PF11762 L-arabinose isomerase C-terminal domain 360 473 9.4E-54 T 06-07-2017 IPR024664 L-arabinose isomerase, C-terminal KEGG: 00040+5.3.1.4 GTHT12_RS13785 5dd1f07905488fce78bf8abf9de586de 343 TIGRFAM TIGR02904 spore_ysxE: spore coat protein YsxE 8 305 8.9E-105 T 06-07-2017 IPR014253 Spore coat protein YsxE GTHT12_RS13785 5dd1f07905488fce78bf8abf9de586de 343 Gene3D G3DSA:3.90.1200.10 96 304 1.9E-15 T 06-07-2017 GTHT12_RS13785 5dd1f07905488fce78bf8abf9de586de 343 Gene3D G3DSA:3.30.200.20 8 88 1.3E-7 T 06-07-2017 GTHT12_RS13785 5dd1f07905488fce78bf8abf9de586de 343 SUPERFAMILY SSF56112 192 285 3.06E-12 T 06-07-2017 IPR011009 Protein kinase-like domain GTHT12_RS13785 5dd1f07905488fce78bf8abf9de586de 343 SUPERFAMILY SSF56112 6 155 3.06E-12 T 06-07-2017 IPR011009 Protein kinase-like domain GTHT12_RS02380 1dda2f06aab2cfae121dc0620a4ef934 558 Pfam PF02652 L-lactate permease 16 549 1.2E-206 T 06-07-2017 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 GTHT12_RS02380 1dda2f06aab2cfae121dc0620a4ef934 558 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 15 549 2.8E-189 T 06-07-2017 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 GTHT12_RS11610 6b4ac3dbbc339edf56152a9a659070a3 418 SMART SM00028 237 270 36.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS11610 6b4ac3dbbc339edf56152a9a659070a3 418 SMART SM00028 339 372 20.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS11610 6b4ac3dbbc339edf56152a9a659070a3 418 SMART SM00028 100 133 470.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS11610 6b4ac3dbbc339edf56152a9a659070a3 418 SMART SM00028 271 304 14.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS11610 6b4ac3dbbc339edf56152a9a659070a3 418 SMART SM00028 373 406 180.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS11610 6b4ac3dbbc339edf56152a9a659070a3 418 SMART SM00028 32 65 230.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS11610 6b4ac3dbbc339edf56152a9a659070a3 418 SMART SM00028 134 167 3.2 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS11610 6b4ac3dbbc339edf56152a9a659070a3 418 SMART SM00028 66 99 270.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS11610 6b4ac3dbbc339edf56152a9a659070a3 418 SMART SM00028 170 203 17.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS11610 6b4ac3dbbc339edf56152a9a659070a3 418 Pfam PF13176 Tetratricopeptide repeat 139 159 0.0012 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS11610 6b4ac3dbbc339edf56152a9a659070a3 418 Pfam PF13176 Tetratricopeptide repeat 175 202 0.0011 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS11610 6b4ac3dbbc339edf56152a9a659070a3 418 Pfam PF13181 Tetratricopeptide repeat 277 301 0.04 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS11610 6b4ac3dbbc339edf56152a9a659070a3 418 Gene3D G3DSA:1.25.40.10 33 188 2.1E-24 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS11610 6b4ac3dbbc339edf56152a9a659070a3 418 Gene3D G3DSA:1.25.40.10 189 416 1.3E-33 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS11610 6b4ac3dbbc339edf56152a9a659070a3 418 Pfam PF14559 Tetratricopeptide repeat 47 98 3.5E-9 T 06-07-2017 GTHT12_RS11610 6b4ac3dbbc339edf56152a9a659070a3 418 SUPERFAMILY SSF48452 203 409 2.28E-26 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS11610 6b4ac3dbbc339edf56152a9a659070a3 418 SUPERFAMILY SSF48452 33 199 2.11E-21 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS09135 d078aee1504aabb4dea98f15dc953d36 151 Pfam PF13279 Thioesterase-like superfamily 14 125 1.3E-16 T 06-07-2017 GTHT12_RS09135 d078aee1504aabb4dea98f15dc953d36 151 Gene3D G3DSA:3.10.129.10 3 133 4.7E-33 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS09135 d078aee1504aabb4dea98f15dc953d36 151 SUPERFAMILY SSF54637 2 136 1.42E-30 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS09845 c25be1b3575f29cae49e500c61086671 467 SUPERFAMILY SSF51556 3 465 3.74E-179 T 06-07-2017 IPR032466 Metal-dependent hydrolase GTHT12_RS09845 c25be1b3575f29cae49e500c61086671 467 Pfam PF02614 Glucuronate isomerase 1 464 2.1E-214 T 06-07-2017 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 GTHT12_RS09845 c25be1b3575f29cae49e500c61086671 467 Gene3D G3DSA:3.20.20.140 4 44 6.5E-148 T 06-07-2017 GTHT12_RS09845 c25be1b3575f29cae49e500c61086671 467 Gene3D G3DSA:3.20.20.140 138 466 6.5E-148 T 06-07-2017 GTHT12_RS09845 c25be1b3575f29cae49e500c61086671 467 Gene3D G3DSA:1.10.2020.10 46 136 7.4E-42 T 06-07-2017 IPR023177 Uronate isomerase, domain 2 GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 GTHT12_RS09845 c25be1b3575f29cae49e500c61086671 467 Hamap MF_00675 Uronate isomerase [uxaC]. 2 466 49.753 T 06-07-2017 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 GTHT12_RS02485 28ae29d3d58e7cb4c7e01a5b20a68f85 277 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 7 266 4.6E-62 T 06-07-2017 IPR017039 Virulence factor BrkB GTHT12_RS02485 28ae29d3d58e7cb4c7e01a5b20a68f85 277 PIRSF PIRSF035875 3 277 6.1E-84 T 06-07-2017 IPR017039 Virulence factor BrkB GTHT12_RS02485 28ae29d3d58e7cb4c7e01a5b20a68f85 277 Pfam PF03631 Virulence factor BrkB 17 266 4.9E-72 T 06-07-2017 IPR017039 Virulence factor BrkB GTHT12_RS06125 a23235783936670f8d378f7408ab339e 218 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 GTHT12_RS06125 a23235783936670f8d378f7408ab339e 218 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 4 213 8.2E-97 T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 GTHT12_RS06125 a23235783936670f8d378f7408ab339e 218 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 GTHT12_RS06125 a23235783936670f8d378f7408ab339e 218 SUPERFAMILY SSF51366 1 215 1.68E-79 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 GTHT12_RS06125 a23235783936670f8d378f7408ab339e 218 Gene3D G3DSA:3.20.20.70 2 216 4.5E-98 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS06125 a23235783936670f8d378f7408ab339e 218 Pfam PF00834 Ribulose-phosphate 3 epimerase family 4 200 9.3E-89 T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 GTHT12_RS06125 a23235783936670f8d378f7408ab339e 218 PIRSF PIRSF001461 1 218 3.6E-99 T 06-07-2017 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 GTHT12_RS10750 8e5a38026537cf3badca5840406fc26b 287 PIRSF PIRSF000105 1 287 4.0E-91 T 06-07-2017 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 GTHT12_RS10750 8e5a38026537cf3badca5840406fc26b 287 SUPERFAMILY SSF51735 2 185 2.32E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS10750 8e5a38026537cf3badca5840406fc26b 287 Gene3D G3DSA:3.40.50.720 2 187 7.8E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS10750 8e5a38026537cf3badca5840406fc26b 287 SUPERFAMILY SSF48179 185 284 1.36E-33 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GTHT12_RS10750 8e5a38026537cf3badca5840406fc26b 287 Gene3D G3DSA:1.10.1040.10 188 281 1.0E-32 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 GTHT12_RS10750 8e5a38026537cf3badca5840406fc26b 287 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 281 6.0E-33 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 GTHT12_RS10750 8e5a38026537cf3badca5840406fc26b 287 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 183 7.0E-61 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 GTHT12_RS08575 2bf36969c61bb7257458f25f90784699 235 SUPERFAMILY SSF52540 2 233 3.17E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08575 2bf36969c61bb7257458f25f90784699 235 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS08575 2bf36969c61bb7257458f25f90784699 235 SMART SM00382 26 229 1.1E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS08575 2bf36969c61bb7257458f25f90784699 235 Gene3D G3DSA:3.40.50.300 1 229 2.8E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08575 2bf36969c61bb7257458f25f90784699 235 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 213 234 8.1E-5 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal GTHT12_RS08575 2bf36969c61bb7257458f25f90784699 235 Pfam PF00005 ABC transporter 18 163 3.5E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS04370 46bfce5ed2517bdd9511c4d4f07c14a6 297 Gene3D G3DSA:3.40.30.10 21 91 1.1E-29 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS04370 46bfce5ed2517bdd9511c4d4f07c14a6 297 SUPERFAMILY SSF52833 24 227 6.09E-35 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS04370 46bfce5ed2517bdd9511c4d4f07c14a6 297 Pfam PF13743 Thioredoxin 29 220 8.4E-76 T 06-07-2017 GTHT12_RS04370 46bfce5ed2517bdd9511c4d4f07c14a6 297 Gene3D G3DSA:1.10.472.60 92 187 2.5E-18 T 06-07-2017 IPR023169 UPF0413, central domain GTHT12_RS03005 909757979c1ff763a0c4d5181fa10fbc 534 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 85 453 2.9E-112 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain GTHT12_RS03005 909757979c1ff763a0c4d5181fa10fbc 534 Gene3D G3DSA:3.10.105.10 304 504 7.5E-68 T 06-07-2017 GTHT12_RS03005 909757979c1ff763a0c4d5181fa10fbc 534 Gene3D G3DSA:3.40.190.10 156 303 2.6E-56 T 06-07-2017 GTHT12_RS03005 909757979c1ff763a0c4d5181fa10fbc 534 SUPERFAMILY SSF53850 37 533 3.33E-157 T 06-07-2017 GTHT12_RS03005 909757979c1ff763a0c4d5181fa10fbc 534 PIRSF PIRSF002741 2 533 1.2E-143 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 GTHT12_RS16920 f9af052e111518fac14d9b4c1df35acc 440 SUPERFAMILY SSF142764 3 424 1.57E-90 T 06-07-2017 GTHT12_RS16920 f9af052e111518fac14d9b4c1df35acc 440 Pfam PF07005 Putative sugar-binding N-terminal domain 3 226 1.2E-57 T 06-07-2017 IPR010737 Putative sugar-binding, N-terminal domain GTHT12_RS16920 f9af052e111518fac14d9b4c1df35acc 440 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 244 415 3.7E-25 T 06-07-2017 IPR031475 Putative nucleotide-binding C-terminal domain GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 857 0.0 T 06-07-2017 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 Gene3D G3DSA:1.10.8.60 343 427 1.9E-36 T 06-07-2017 GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 SUPERFAMILY SSF81923 5 155 5.59E-41 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 Gene3D G3DSA:1.10.8.60 779 858 1.5E-30 T 06-07-2017 GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 SUPERFAMILY SSF52540 157 547 8.18E-100 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 SMART SM01086 768 857 4.8E-37 T 06-07-2017 IPR019489 Clp ATPase, C-terminal GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 768 848 4.7E-25 T 06-07-2017 IPR019489 Clp ATPase, C-terminal GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 06-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 335 8.2E-14 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 Gene3D G3DSA:1.10.1780.10 1 148 9.2E-41 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 SUPERFAMILY SSF52540 548 856 6.64E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 SMART SM00382 599 741 5.1E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 SMART SM00382 198 343 2.7E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 Gene3D G3DSA:3.40.50.300 159 342 6.1E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 633 651 - T 06-07-2017 IPR028299 ClpA/B, conserved site 2 GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 603 621 7.4E-43 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 677 695 7.4E-43 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 710 724 7.4E-43 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 666 7.4E-43 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 145 3.6E-9 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 61 9.5E-14 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 Pfam PF07724 AAA domain (Cdc48 subfamily) 598 761 1.8E-56 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 GTHT12_RS04240 e4f3dd40efef78a9038d66ed17af0f2f 861 Gene3D G3DSA:3.40.50.300 553 778 7.2E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS15100 345ec70d70536abcda7b409a047e96c6 241 Pfam PF03473 MOSC domain 123 237 2.6E-19 T 06-07-2017 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 GTHT12_RS15100 345ec70d70536abcda7b409a047e96c6 241 SUPERFAMILY SSF50800 126 238 9.0E-19 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain GTHT12_RS15100 345ec70d70536abcda7b409a047e96c6 241 SUPERFAMILY SSF50800 3 46 9.0E-19 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain GTHT12_RS15100 345ec70d70536abcda7b409a047e96c6 241 Pfam PF03476 MOSC N-terminal beta barrel domain 4 90 1.4E-11 T 06-07-2017 IPR005303 MOSC, N-terminal beta barrel GTHT12_RS15100 345ec70d70536abcda7b409a047e96c6 241 Gene3D G3DSA:2.40.33.20 143 238 5.5E-6 T 06-07-2017 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like GTHT12_RS07525 6247afc102f9e5f145e1a23fa3d183bc 433 PRINTS PR00342 Rhesus blood group protein signature 207 225 5.4E-6 T 06-07-2017 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 GTHT12_RS07525 6247afc102f9e5f145e1a23fa3d183bc 433 PRINTS PR00342 Rhesus blood group protein signature 122 138 5.4E-6 T 06-07-2017 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 GTHT12_RS07525 6247afc102f9e5f145e1a23fa3d183bc 433 PRINTS PR00342 Rhesus blood group protein signature 327 343 5.4E-6 T 06-07-2017 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 GTHT12_RS07525 6247afc102f9e5f145e1a23fa3d183bc 433 PRINTS PR00342 Rhesus blood group protein signature 272 285 5.4E-6 T 06-07-2017 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 GTHT12_RS07525 6247afc102f9e5f145e1a23fa3d183bc 433 TIGRFAM TIGR00836 amt: ammonium transporter 11 417 1.1E-122 T 06-07-2017 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 GTHT12_RS07525 6247afc102f9e5f145e1a23fa3d183bc 433 SUPERFAMILY SSF111352 9 398 4.84E-109 T 06-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 GTHT12_RS07525 6247afc102f9e5f145e1a23fa3d183bc 433 ProSitePatterns PS01219 Ammonium transporters signature. 163 188 - T 06-07-2017 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 GTHT12_RS07525 6247afc102f9e5f145e1a23fa3d183bc 433 Gene3D G3DSA:1.10.3430.10 8 398 4.8E-114 T 06-07-2017 IPR029020 Ammonium/urea transporter GTHT12_RS07525 6247afc102f9e5f145e1a23fa3d183bc 433 Pfam PF00909 Ammonium Transporter Family 13 417 7.8E-113 T 06-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 GTHT12_RS11780 49f64fa417a9cca98994331fefda18ea 514 PIRSF PIRSF005690 23 514 1.3E-174 T 06-07-2017 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 GTHT12_RS11780 49f64fa417a9cca98994331fefda18ea 514 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 37 503 5.2E-187 T 06-07-2017 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 GTHT12_RS16390 cf42ec19265f77baf652bbbac432ddf7 866 SMART SM00047 559 707 3.9E-5 T 06-07-2017 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 GTHT12_RS16390 cf42ec19265f77baf652bbbac432ddf7 866 Gene3D G3DSA:2.30.30.40 64 112 7.6E-4 T 06-07-2017 GTHT12_RS16390 cf42ec19265f77baf652bbbac432ddf7 866 Gene3D G3DSA:2.30.30.40 149 197 8.3E-4 T 06-07-2017 GTHT12_RS16390 cf42ec19265f77baf652bbbac432ddf7 866 Gene3D G3DSA:2.30.30.40 484 522 7.8E-4 T 06-07-2017 GTHT12_RS16390 cf42ec19265f77baf652bbbac432ddf7 866 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 572 698 3.7E-18 T 06-07-2017 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 GTHT12_RS16390 cf42ec19265f77baf652bbbac432ddf7 866 Pfam PF08239 Bacterial SH3 domain 49 107 3.9E-12 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS16390 cf42ec19265f77baf652bbbac432ddf7 866 Pfam PF08239 Bacterial SH3 domain 134 192 8.5E-12 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS16390 cf42ec19265f77baf652bbbac432ddf7 866 Pfam PF08239 Bacterial SH3 domain 468 518 1.1E-12 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS16390 cf42ec19265f77baf652bbbac432ddf7 866 Pfam PF08239 Bacterial SH3 domain 227 285 3.3E-12 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS16390 cf42ec19265f77baf652bbbac432ddf7 866 Pfam PF08239 Bacterial SH3 domain 806 861 2.0E-10 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS16390 cf42ec19265f77baf652bbbac432ddf7 866 Pfam PF08239 Bacterial SH3 domain 375 423 8.6E-7 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS16390 cf42ec19265f77baf652bbbac432ddf7 866 SMART SM00287 218 287 1.2E-7 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS16390 cf42ec19265f77baf652bbbac432ddf7 866 SMART SM00287 294 360 0.23 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS16390 cf42ec19265f77baf652bbbac432ddf7 866 SMART SM00287 40 110 6.4E-8 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS16390 cf42ec19265f77baf652bbbac432ddf7 866 SMART SM00287 728 791 24.0 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS16390 cf42ec19265f77baf652bbbac432ddf7 866 SMART SM00287 366 427 0.3 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS16390 cf42ec19265f77baf652bbbac432ddf7 866 SMART SM00287 458 521 9.4E-6 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS16390 cf42ec19265f77baf652bbbac432ddf7 866 SMART SM00287 797 865 0.047 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS16390 cf42ec19265f77baf652bbbac432ddf7 866 SMART SM00287 125 195 4.8E-9 T 06-07-2017 IPR003646 SH3-like domain, bacterial-type GTHT12_RS03415 99307404f28af921e7bc056f18a7667d 448 PIRSF PIRSF006446 2 447 2.0E-147 T 06-07-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 GTHT12_RS03415 99307404f28af921e7bc056f18a7667d 448 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 9 432 4.6E-129 T 06-07-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 GTHT12_RS09420 5d8b39d5f570ea4d378128242e10f4f3 394 Pfam PF11761 Cobalamin biosynthesis central region 150 245 1.4E-15 T 06-07-2017 IPR021745 Cobalamin biosynthesis central region KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 GTHT12_RS09420 5d8b39d5f570ea4d378128242e10f4f3 394 SUPERFAMILY SSF159664 241 368 1.27E-36 T 06-07-2017 IPR002750 CobE/GbiG C-terminal domain GO:0009236 GTHT12_RS09420 5d8b39d5f570ea4d378128242e10f4f3 394 Pfam PF11760 Cobalamin synthesis G N-terminal 66 145 2.7E-37 T 06-07-2017 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 GTHT12_RS09420 5d8b39d5f570ea4d378128242e10f4f3 394 SUPERFAMILY SSF159672 14 255 9.94E-63 T 06-07-2017 GTHT12_RS09420 5d8b39d5f570ea4d378128242e10f4f3 394 Gene3D G3DSA:3.30.420.180 241 366 1.5E-34 T 06-07-2017 IPR002750 CobE/GbiG C-terminal domain GO:0009236 GTHT12_RS09420 5d8b39d5f570ea4d378128242e10f4f3 394 Pfam PF01890 Cobalamin synthesis G C-terminus 248 365 1.7E-33 T 06-07-2017 IPR002750 CobE/GbiG C-terminal domain GO:0009236 GTHT12_RS06895 5c71314490473baa8bd1e8d1b930f42f 668 SUPERFAMILY SSF52518 4 326 9.32E-122 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS06895 5c71314490473baa8bd1e8d1b930f42f 668 Gene3D G3DSA:3.40.50.970 334 531 1.9E-78 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS06895 5c71314490473baa8bd1e8d1b930f42f 668 Gene3D G3DSA:3.40.50.970 4 327 1.2E-128 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS06895 5c71314490473baa8bd1e8d1b930f42f 668 Pfam PF02780 Transketolase, C-terminal domain 552 658 2.0E-9 T 06-07-2017 IPR033248 Transketolase, C-terminal domain GTHT12_RS06895 5c71314490473baa8bd1e8d1b930f42f 668 SUPERFAMILY SSF52518 342 527 3.31E-70 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS06895 5c71314490473baa8bd1e8d1b930f42f 668 TIGRFAM TIGR00232 tktlase_bact: transketolase 9 666 1.4E-303 T 06-07-2017 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 GTHT12_RS06895 5c71314490473baa8bd1e8d1b930f42f 668 Gene3D G3DSA:3.40.50.920 540 666 3.4E-47 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GTHT12_RS06895 5c71314490473baa8bd1e8d1b930f42f 668 ProSitePatterns PS00801 Transketolase signature 1. 14 34 - T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 GTHT12_RS06895 5c71314490473baa8bd1e8d1b930f42f 668 SUPERFAMILY SSF52922 532 667 3.8E-41 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GTHT12_RS06895 5c71314490473baa8bd1e8d1b930f42f 668 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 6 339 1.2E-158 T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 GTHT12_RS06895 5c71314490473baa8bd1e8d1b930f42f 668 ProSitePatterns PS00802 Transketolase signature 2. 468 484 - T 06-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 GTHT12_RS06895 5c71314490473baa8bd1e8d1b930f42f 668 Pfam PF02779 Transketolase, pyrimidine binding domain 354 525 9.6E-45 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain GTHT12_RS06895 5c71314490473baa8bd1e8d1b930f42f 668 SMART SM00861 355 526 1.3E-69 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain GTHT12_RS15350 92d62e0fa1a89ce4654acfb9458534ea 490 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 132 151 4.8E-14 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS15350 92d62e0fa1a89ce4654acfb9458534ea 490 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 162 186 4.8E-14 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS15350 92d62e0fa1a89ce4654acfb9458534ea 490 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 234 258 4.8E-14 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS15350 92d62e0fa1a89ce4654acfb9458534ea 490 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 374 400 4.8E-14 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS15350 92d62e0fa1a89ce4654acfb9458534ea 490 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 322 341 4.8E-14 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS15350 92d62e0fa1a89ce4654acfb9458534ea 490 Pfam PF00361 Proton-conducting membrane transporter 128 414 1.2E-44 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS02065 145a5ba4e8e602f944e2b473f221b96d 489 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 87 102 - T 06-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 GTHT12_RS02065 145a5ba4e8e602f944e2b473f221b96d 489 PRINTS PR00175 Sodium/alanine symporter signature 296 314 2.0E-55 T 06-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 GTHT12_RS02065 145a5ba4e8e602f944e2b473f221b96d 489 PRINTS PR00175 Sodium/alanine symporter signature 87 109 2.0E-55 T 06-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 GTHT12_RS02065 145a5ba4e8e602f944e2b473f221b96d 489 PRINTS PR00175 Sodium/alanine symporter signature 205 224 2.0E-55 T 06-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 GTHT12_RS02065 145a5ba4e8e602f944e2b473f221b96d 489 PRINTS PR00175 Sodium/alanine symporter signature 177 195 2.0E-55 T 06-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 GTHT12_RS02065 145a5ba4e8e602f944e2b473f221b96d 489 PRINTS PR00175 Sodium/alanine symporter signature 355 377 2.0E-55 T 06-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 GTHT12_RS02065 145a5ba4e8e602f944e2b473f221b96d 489 PRINTS PR00175 Sodium/alanine symporter signature 418 438 2.0E-55 T 06-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 GTHT12_RS02065 145a5ba4e8e602f944e2b473f221b96d 489 Pfam PF01235 Sodium:alanine symporter family 52 461 1.2E-150 T 06-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 GTHT12_RS02065 145a5ba4e8e602f944e2b473f221b96d 489 TIGRFAM TIGR00835 agcS: amino acid carrier protein 14 449 6.0E-150 T 06-07-2017 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 GTHT12_RS10795 8acec0a74e2137f7a3a908353e758dbf 443 Gene3D G3DSA:3.30.300.30 324 437 1.9E-34 T 06-07-2017 GTHT12_RS10795 8acec0a74e2137f7a3a908353e758dbf 443 Pfam PF14535 AMP-binding enzyme C-terminal domain 334 435 6.7E-23 T 06-07-2017 IPR028154 AMP-dependent ligase, C-terminal GTHT12_RS10795 8acec0a74e2137f7a3a908353e758dbf 443 Gene3D G3DSA:3.40.50.980 88 243 6.6E-13 T 06-07-2017 GTHT12_RS10795 8acec0a74e2137f7a3a908353e758dbf 443 PIRSF PIRSF006444 1 437 1.6E-197 T 06-07-2017 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 GTHT12_RS10795 8acec0a74e2137f7a3a908353e758dbf 443 Pfam PF00501 AMP-binding enzyme 82 333 5.8E-16 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GTHT12_RS10795 8acec0a74e2137f7a3a908353e758dbf 443 SUPERFAMILY SSF56801 23 379 8.11E-65 T 06-07-2017 GTHT12_RS10795 8acec0a74e2137f7a3a908353e758dbf 443 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 7 435 3.1E-195 T 06-07-2017 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 GTHT12_RS01255 7a12b9859cec9b4abde2eb4a7e992d18 273 Pfam PF02673 Bacitracin resistance protein BacA 9 266 1.7E-73 T 06-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 GTHT12_RS01255 7a12b9859cec9b4abde2eb4a7e992d18 273 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 272 17.864 T 06-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 GTHT12_RS01255 7a12b9859cec9b4abde2eb4a7e992d18 273 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 265 2.3E-88 T 06-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 GTHT12_RS14710 ed04922f57dff7745624432b3784777d 248 SMART SM00363 3 62 6.5E-8 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS14710 ed04922f57dff7745624432b3784777d 248 Gene3D G3DSA:3.10.290.10 3 66 1.2E-17 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS14710 ed04922f57dff7745624432b3784777d 248 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 102 116 - T 06-07-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 GTHT12_RS14710 ed04922f57dff7745624432b3784777d 248 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 68 229 5.1E-47 T 06-07-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 GTHT12_RS14710 ed04922f57dff7745624432b3784777d 248 SUPERFAMILY SSF55120 47 238 1.6E-46 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS14710 ed04922f57dff7745624432b3784777d 248 SUPERFAMILY SSF55174 3 60 1.18E-12 T 06-07-2017 GTHT12_RS14710 ed04922f57dff7745624432b3784777d 248 Pfam PF00849 RNA pseudouridylate synthase 64 197 1.6E-20 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS14710 ed04922f57dff7745624432b3784777d 248 Pfam PF01479 S4 domain 4 47 1.0E-9 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS01670 b5ec22c855e195b69db4922b6dc6dd17 105 Gene3D G3DSA:1.10.1270.10 1 101 1.0E-48 T 06-07-2017 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 GTHT12_RS01670 b5ec22c855e195b69db4922b6dc6dd17 105 PIRSF PIRSF012508 1 100 6.8E-49 T 06-07-2017 IPR013368 TrpR homologue YerC/YecD GTHT12_RS01670 b5ec22c855e195b69db4922b6dc6dd17 105 Pfam PF01371 Trp repressor protein 10 93 9.3E-35 T 06-07-2017 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 GTHT12_RS01670 b5ec22c855e195b69db4922b6dc6dd17 105 SUPERFAMILY SSF48295 3 95 1.1E-33 T 06-07-2017 IPR010921 Trp repressor/replication initiator GO:0043565 GTHT12_RS01670 b5ec22c855e195b69db4922b6dc6dd17 105 TIGRFAM TIGR02531 yecD_yerC: TrpR homolog YerC/YecD 7 94 3.4E-49 T 06-07-2017 IPR013368 TrpR homologue YerC/YecD GTHT12_RS01025 9b3430f3fec40f49488baa38b17e0dac 412 Pfam PF00425 chorismate binding enzyme 127 396 1.1E-81 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal GTHT12_RS01025 9b3430f3fec40f49488baa38b17e0dac 412 Gene3D G3DSA:3.60.120.10 121 407 7.7E-98 T 06-07-2017 IPR005801 ADC synthase GO:0009058 GTHT12_RS01025 9b3430f3fec40f49488baa38b17e0dac 412 Gene3D G3DSA:3.60.120.10 48 81 7.7E-98 T 06-07-2017 IPR005801 ADC synthase GO:0009058 GTHT12_RS01025 9b3430f3fec40f49488baa38b17e0dac 412 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 125 402 1.3E-85 T 06-07-2017 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 GTHT12_RS01025 9b3430f3fec40f49488baa38b17e0dac 412 SUPERFAMILY SSF56322 19 406 7.06E-98 T 06-07-2017 IPR005801 ADC synthase GO:0009058 GTHT12_RS14760 3464b8c8335f3a0c1dc47cb82d4812a7 319 Pfam PF04055 Radical SAM superfamily 52 212 7.5E-15 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 GTHT12_RS14760 3464b8c8335f3a0c1dc47cb82d4812a7 319 Gene3D G3DSA:3.20.20.70 12 268 6.1E-31 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS14760 3464b8c8335f3a0c1dc47cb82d4812a7 319 SMART SM00729 31 258 5.3E-42 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 GTHT12_RS14760 3464b8c8335f3a0c1dc47cb82d4812a7 319 SUPERFAMILY SSF102114 5 313 2.35E-56 T 06-07-2017 GTHT12_RS14760 3464b8c8335f3a0c1dc47cb82d4812a7 319 Pfam PF16199 Radical_SAM C-terminal domain 219 302 2.5E-26 T 06-07-2017 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 GTHT12_RS14760 3464b8c8335f3a0c1dc47cb82d4812a7 319 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 14 313 1.0E-137 T 06-07-2017 IPR005911 Protein YhcC-like GO:0051536 GTHT12_RS03670 0651be80f32deaf08e8413dc4195e1ac 245 SMART SM00382 28 213 1.7E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS03670 0651be80f32deaf08e8413dc4195e1ac 245 Pfam PF00005 ABC transporter 19 162 2.8E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS03670 0651be80f32deaf08e8413dc4195e1ac 245 SUPERFAMILY SSF52540 3 229 2.45E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03670 0651be80f32deaf08e8413dc4195e1ac 245 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS03670 0651be80f32deaf08e8413dc4195e1ac 245 Gene3D G3DSA:3.40.50.300 3 229 3.3E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08600 39b6b503777a6d2c3a88d929d9049f6f 179 SUPERFAMILY SSF49503 51 172 1.09E-23 T 06-07-2017 IPR008972 Cupredoxin GTHT12_RS08600 39b6b503777a6d2c3a88d929d9049f6f 179 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 112 164 - T 06-07-2017 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS08600 39b6b503777a6d2c3a88d929d9049f6f 179 Gene3D G3DSA:2.60.40.420 7 23 1.6E-22 T 06-07-2017 IPR008972 Cupredoxin GTHT12_RS08600 39b6b503777a6d2c3a88d929d9049f6f 179 Gene3D G3DSA:2.60.40.420 59 172 1.6E-22 T 06-07-2017 IPR008972 Cupredoxin GTHT12_RS08600 39b6b503777a6d2c3a88d929d9049f6f 179 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 99 169 3.9E-5 T 06-07-2017 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05800 7a65495bd8a212b0c8d3fb9723819962 406 Gene3D G3DSA:3.40.50.620 1 234 2.7E-79 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS05800 7a65495bd8a212b0c8d3fb9723819962 406 Hamap MF_01539 UPF0348 protein . 2 399 40.507 T 06-07-2017 IPR008513 Uncharacterised protein family UPF0348 GTHT12_RS05800 7a65495bd8a212b0c8d3fb9723819962 406 SUPERFAMILY SSF52374 10 105 4.16E-19 T 06-07-2017 GTHT12_RS05800 7a65495bd8a212b0c8d3fb9723819962 406 SUPERFAMILY SSF52374 197 237 4.16E-19 T 06-07-2017 GTHT12_RS05800 7a65495bd8a212b0c8d3fb9723819962 406 Pfam PF05636 HIGH Nucleotidyl Transferase 1 381 1.4E-137 T 06-07-2017 IPR008513 Uncharacterised protein family UPF0348 GTHT12_RS06345 a9133af857666eeeea015e171ceb11d0 437 SMART SM00382 156 337 4.2E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS06345 a9133af857666eeeea015e171ceb11d0 437 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 144 353 2.7E-76 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GTHT12_RS06345 a9133af857666eeeea015e171ceb11d0 437 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 22 87 6.0E-7 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GTHT12_RS06345 a9133af857666eeeea015e171ceb11d0 437 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 344 353 - T 06-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GTHT12_RS06345 a9133af857666eeeea015e171ceb11d0 437 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 13 432 2.1E-194 T 06-07-2017 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GTHT12_RS06345 a9133af857666eeeea015e171ceb11d0 437 Gene3D G3DSA:3.40.50.300 123 394 6.7E-96 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06345 a9133af857666eeeea015e171ceb11d0 437 TIGRFAM TIGR03497 FliI_clade2: flagellar protein export ATPase FliI 20 430 6.9E-202 T 06-07-2017 IPR022425 Flagellar export ATPase FliI, clade 2 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GTHT12_RS06345 a9133af857666eeeea015e171ceb11d0 437 SUPERFAMILY SSF52540 91 359 4.59E-97 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00510 30de79dea4489728247daba47d6a997e 182 Gene3D G3DSA:4.10.860.10 137 173 8.9E-7 T 06-07-2017 IPR001943 UVR domain GO:0005515 GTHT12_RS00510 30de79dea4489728247daba47d6a997e 182 Pfam PF02151 UvrB/uvrC motif 139 172 5.9E-9 T 06-07-2017 IPR001943 UVR domain GO:0005515 GTHT12_RS00510 30de79dea4489728247daba47d6a997e 182 SUPERFAMILY SSF46600 138 174 1.15E-6 T 06-07-2017 IPR001943 UVR domain GO:0005515 GTHT12_RS00510 30de79dea4489728247daba47d6a997e 182 PIRSF PIRSF015034 1 181 3.8E-64 T 06-07-2017 IPR025542 YacH protein GTHT12_RS17570 f270d0fcd1a4544e090fa4c1a91d5d39 358 SMART SM00937 63 177 2.8E-67 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 GTHT12_RS17570 f270d0fcd1a4544e090fa4c1a91d5d39 358 Gene3D G3DSA:1.20.58.410 3 91 3.0E-21 T 06-07-2017 GTHT12_RS17570 f270d0fcd1a4544e090fa4c1a91d5d39 358 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 355 40.992 T 06-07-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 GTHT12_RS17570 f270d0fcd1a4544e090fa4c1a91d5d39 358 Pfam PF00472 RF-1 domain 210 319 9.0E-43 T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 GTHT12_RS17570 f270d0fcd1a4544e090fa4c1a91d5d39 358 Gene3D G3DSA:3.30.160.20 209 286 7.4E-35 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain GTHT12_RS17570 f270d0fcd1a4544e090fa4c1a91d5d39 358 Pfam PF03462 PCRF domain 9 202 3.8E-75 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 GTHT12_RS17570 f270d0fcd1a4544e090fa4c1a91d5d39 358 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 GTHT12_RS17570 f270d0fcd1a4544e090fa4c1a91d5d39 358 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 354 8.2E-171 T 06-07-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 GTHT12_RS17570 f270d0fcd1a4544e090fa4c1a91d5d39 358 SUPERFAMILY SSF75620 8 351 3.4E-136 T 06-07-2017 GTHT12_RS07535 06c6bbdc91b7fb905f12eb378375522c 242 Gene3D G3DSA:3.30.420.10 56 232 2.5E-38 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS07535 06c6bbdc91b7fb905f12eb378375522c 242 Pfam PF00929 Exonuclease 63 216 1.1E-20 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III GTHT12_RS07535 06c6bbdc91b7fb905f12eb378375522c 242 SMART SM00479 61 226 1.0E-23 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III GTHT12_RS07535 06c6bbdc91b7fb905f12eb378375522c 242 SUPERFAMILY SSF53098 53 230 1.39E-41 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 SUPERFAMILY SSF52540 162 467 8.75E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 SMART SM00382 538 682 3.4E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 SMART SM00382 201 346 3.8E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 SUPERFAMILY SSF52540 487 803 4.41E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 Gene3D G3DSA:1.10.1780.10 1 145 3.6E-50 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 Pfam PF07724 AAA domain (Cdc48 subfamily) 537 709 1.3E-58 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 206 318 7.0E-14 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 572 590 - T 06-07-2017 IPR028299 ClpA/B, conserved site 2 GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 06-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 69 3.2E-18 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 143 2.0E-18 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 Gene3D G3DSA:3.40.50.300 163 344 1.1E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 SUPERFAMILY SSF81923 5 145 3.01E-33 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 715 795 3.8E-26 T 06-07-2017 IPR019489 Clp ATPase, C-terminal GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 Gene3D G3DSA:1.10.8.60 727 805 5.7E-31 T 06-07-2017 GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 Gene3D G3DSA:1.10.8.60 345 429 1.2E-36 T 06-07-2017 GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 Pfam PF02151 UvrB/uvrC motif 418 452 7.4E-7 T 06-07-2017 IPR001943 UVR domain GO:0005515 GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 Gene3D G3DSA:3.40.50.300 698 726 8.7E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 Gene3D G3DSA:3.40.50.300 491 664 8.7E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 587 605 9.1E-43 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 616 634 9.1E-43 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 542 560 9.1E-43 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 649 663 9.1E-43 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 GTHT12_RS00520 0b3cc8ed48db2c27e743e0f264dc6a54 811 SMART SM01086 715 804 2.8E-38 T 06-07-2017 IPR019489 Clp ATPase, C-terminal GTHT12_RS03735 ea9dc593ebe04a93780fc7e7405ca9b5 265 SMART SM00382 31 254 1.3E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS03735 ea9dc593ebe04a93780fc7e7405ca9b5 265 Gene3D G3DSA:3.40.50.300 2 235 3.2E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03735 ea9dc593ebe04a93780fc7e7405ca9b5 265 SUPERFAMILY SSF52540 2 232 7.93E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03735 ea9dc593ebe04a93780fc7e7405ca9b5 265 Pfam PF00005 ABC transporter 22 177 4.8E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS03735 ea9dc593ebe04a93780fc7e7405ca9b5 265 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS12040 805bfbadf3a92390e6e6d4f988e9bf06 243 Pfam PF01479 S4 domain 2 48 1.2E-15 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS12040 805bfbadf3a92390e6e6d4f988e9bf06 243 SUPERFAMILY SSF55174 2 67 1.12E-17 T 06-07-2017 GTHT12_RS12040 805bfbadf3a92390e6e6d4f988e9bf06 243 Gene3D G3DSA:3.10.290.10 2 64 3.0E-27 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS12040 805bfbadf3a92390e6e6d4f988e9bf06 243 SUPERFAMILY SSF55120 46 236 1.3E-46 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS12040 805bfbadf3a92390e6e6d4f988e9bf06 243 Pfam PF00849 RNA pseudouridylate synthase 62 196 1.0E-23 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS12040 805bfbadf3a92390e6e6d4f988e9bf06 243 SMART SM00363 2 65 3.0E-16 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS12040 805bfbadf3a92390e6e6d4f988e9bf06 243 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 06-07-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 GTHT12_RS12040 805bfbadf3a92390e6e6d4f988e9bf06 243 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 226 1.6E-54 T 06-07-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 GTHT12_RS08755 b6e46471fc9170a0d56237a4e6980387 85 Pfam PF02675 S-adenosylmethionine decarboxylase 2 69 9.2E-18 T 06-07-2017 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 GTHT12_RS08755 b6e46471fc9170a0d56237a4e6980387 85 SUPERFAMILY SSF56276 3 69 2.51E-15 T 06-07-2017 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 GTHT12_RS08755 b6e46471fc9170a0d56237a4e6980387 85 Gene3D G3DSA:3.60.90.10 1 71 3.3E-20 T 06-07-2017 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 GTHT12_RS04785 84edae295320e607c6933b22dedd502a 349 Pfam PF01012 Electron transfer flavoprotein domain 9 185 7.6E-42 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 GTHT12_RS04785 84edae295320e607c6933b22dedd502a 349 SUPERFAMILY SSF52467 210 328 3.97E-48 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS04785 84edae295320e607c6933b22dedd502a 349 PIRSF PIRSF000089 5 333 1.4E-113 T 06-07-2017 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 GTHT12_RS04785 84edae295320e607c6933b22dedd502a 349 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 210 292 9.1E-36 T 06-07-2017 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 GTHT12_RS04785 84edae295320e607c6933b22dedd502a 349 Gene3D G3DSA:3.40.50.1220 203 330 4.0E-55 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS04785 84edae295320e607c6933b22dedd502a 349 Gene3D G3DSA:3.40.50.620 7 202 4.6E-73 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS04785 84edae295320e607c6933b22dedd502a 349 SUPERFAMILY SSF52402 8 203 1.19E-53 T 06-07-2017 GTHT12_RS04785 84edae295320e607c6933b22dedd502a 349 SMART SM00893 9 198 1.8E-44 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 GTHT12_RS00705 4a1d98d12edfce44f944ef0ff5573edf 87 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 5 83 24.994 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00705 4a1d98d12edfce44f944ef0ff5573edf 87 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 78 1.2E-35 T 06-07-2017 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00705 4a1d98d12edfce44f944ef0ff5573edf 87 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 7 78 5.0E-35 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00705 4a1d98d12edfce44f944ef0ff5573edf 87 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 7.9E-13 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00705 4a1d98d12edfce44f944ef0ff5573edf 87 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 7.9E-13 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00705 4a1d98d12edfce44f944ef0ff5573edf 87 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 7.9E-13 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00705 4a1d98d12edfce44f944ef0ff5573edf 87 Gene3D G3DSA:2.40.50.140 7 84 2.7E-35 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS00705 4a1d98d12edfce44f944ef0ff5573edf 87 ProSitePatterns PS00056 Ribosomal protein S17 signature. 58 70 - T 06-07-2017 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00705 4a1d98d12edfce44f944ef0ff5573edf 87 SUPERFAMILY SSF50249 7 84 3.34E-32 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS00705 4a1d98d12edfce44f944ef0ff5573edf 87 Pfam PF00366 Ribosomal protein S17 12 79 1.5E-33 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS11735 4200deccca9262e7f0f45649d084dbbe 436 SUPERFAMILY SSF52540 4 170 6.71E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11735 4200deccca9262e7f0f45649d084dbbe 436 Gene3D G3DSA:3.30.300.20 359 435 4.1E-39 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta GTHT12_RS11735 4200deccca9262e7f0f45649d084dbbe 436 Hamap MF_00195 GTPase Der [der]. 3 436 41.694 T 06-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 GTHT12_RS11735 4200deccca9262e7f0f45649d084dbbe 436 Gene3D G3DSA:3.40.50.300 4 172 4.7E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11735 4200deccca9262e7f0f45649d084dbbe 436 Gene3D G3DSA:3.40.50.300 173 358 1.6E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11735 4200deccca9262e7f0f45649d084dbbe 436 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 432 5.2E-181 T 06-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 GTHT12_RS11735 4200deccca9262e7f0f45649d084dbbe 436 SUPERFAMILY SSF52540 138 433 1.27E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11735 4200deccca9262e7f0f45649d084dbbe 436 Pfam PF01926 50S ribosome-binding GTPase 6 120 2.6E-26 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS11735 4200deccca9262e7f0f45649d084dbbe 436 Pfam PF01926 50S ribosome-binding GTPase 178 295 6.0E-26 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS11735 4200deccca9262e7f0f45649d084dbbe 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 154 2.8E-24 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 GTHT12_RS11735 4200deccca9262e7f0f45649d084dbbe 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 176 339 5.4E-27 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 GTHT12_RS11735 4200deccca9262e7f0f45649d084dbbe 436 PIRSF PIRSF006485 2 436 4.0E-174 T 06-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 GTHT12_RS11735 4200deccca9262e7f0f45649d084dbbe 436 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 433 3.6E-36 T 06-07-2017 IPR032859 GTPase Der, C-terminal KH-domain-like GTHT12_RS05575 47cefa69c70a649c2512408b79dc7447 369 SUPERFAMILY SSF52518 20 364 1.73E-103 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS05575 47cefa69c70a649c2512408b79dc7447 369 Pfam PF00676 Dehydrogenase E1 component 51 341 6.9E-107 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 GTHT12_RS05575 47cefa69c70a649c2512408b79dc7447 369 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 23 362 4.7E-146 T 06-07-2017 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 GTHT12_RS05575 47cefa69c70a649c2512408b79dc7447 369 Gene3D G3DSA:3.40.50.970 15 361 7.4E-126 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS12095 b7477cd0a0158c1147bf1487d1e948b0 116 Gene3D G3DSA:3.40.630.30 27 101 5.3E-13 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS12095 b7477cd0a0158c1147bf1487d1e948b0 116 Pfam PF13673 Acetyltransferase (GNAT) domain 31 95 4.3E-9 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS12095 b7477cd0a0158c1147bf1487d1e948b0 116 SUPERFAMILY SSF55729 8 95 5.82E-14 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS14590 e2e58e4fe732975b988bc9103fa02078 389 SUPERFAMILY SSF52768 5 374 6.23E-109 T 06-07-2017 GTHT12_RS14590 e2e58e4fe732975b988bc9103fa02078 389 PRINTS PR01270 Histone deacetylase superfamily signature 130 153 1.7E-17 T 06-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 GTHT12_RS14590 e2e58e4fe732975b988bc9103fa02078 389 PRINTS PR01270 Histone deacetylase superfamily signature 249 259 1.7E-17 T 06-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 GTHT12_RS14590 e2e58e4fe732975b988bc9103fa02078 389 PRINTS PR01270 Histone deacetylase superfamily signature 163 178 1.7E-17 T 06-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 GTHT12_RS14590 e2e58e4fe732975b988bc9103fa02078 389 Pfam PF00850 Histone deacetylase domain 22 316 4.2E-77 T 06-07-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 GTHT12_RS14590 e2e58e4fe732975b988bc9103fa02078 389 PRINTS PR01272 Acetoin utilisation ACUC protein signature 16 36 5.1E-42 T 06-07-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 GTHT12_RS14590 e2e58e4fe732975b988bc9103fa02078 389 PRINTS PR01272 Acetoin utilisation ACUC protein signature 86 100 5.1E-42 T 06-07-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 GTHT12_RS14590 e2e58e4fe732975b988bc9103fa02078 389 PRINTS PR01272 Acetoin utilisation ACUC protein signature 351 370 5.1E-42 T 06-07-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 GTHT12_RS14590 e2e58e4fe732975b988bc9103fa02078 389 PRINTS PR01272 Acetoin utilisation ACUC protein signature 107 120 5.1E-42 T 06-07-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 GTHT12_RS14590 e2e58e4fe732975b988bc9103fa02078 389 PRINTS PR01272 Acetoin utilisation ACUC protein signature 334 350 5.1E-42 T 06-07-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 GTHT12_RS14590 e2e58e4fe732975b988bc9103fa02078 389 PRINTS PR01272 Acetoin utilisation ACUC protein signature 274 290 5.1E-42 T 06-07-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 GTHT12_RS14590 e2e58e4fe732975b988bc9103fa02078 389 PRINTS PR01272 Acetoin utilisation ACUC protein signature 313 332 5.1E-42 T 06-07-2017 IPR003085 Acetoin utilization protein AcuC GO:0045149 GTHT12_RS14590 e2e58e4fe732975b988bc9103fa02078 389 Gene3D G3DSA:3.40.800.20 3 328 2.2E-93 T 06-07-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 GTHT12_RS01250 52571f98389490a27e044964d5cae55c 309 Pfam PF00480 ROK family 5 295 2.7E-48 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 GTHT12_RS01250 52571f98389490a27e044964d5cae55c 309 Gene3D G3DSA:3.30.420.40 106 300 3.4E-60 T 06-07-2017 GTHT12_RS01250 52571f98389490a27e044964d5cae55c 309 SUPERFAMILY SSF53067 1 300 1.07E-60 T 06-07-2017 GTHT12_RS01250 52571f98389490a27e044964d5cae55c 309 Gene3D G3DSA:3.30.420.40 1 105 2.0E-27 T 06-07-2017 GTHT12_RS02840 c1dfc67b072bfe2f684642be76de9944 500 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 230 256 1.4E-10 T 06-07-2017 GTHT12_RS02840 c1dfc67b072bfe2f684642be76de9944 500 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 66 91 1.4E-10 T 06-07-2017 GTHT12_RS02840 c1dfc67b072bfe2f684642be76de9944 500 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 208 229 1.4E-10 T 06-07-2017 GTHT12_RS02840 c1dfc67b072bfe2f684642be76de9944 500 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 296 308 1.4E-10 T 06-07-2017 GTHT12_RS02840 c1dfc67b072bfe2f684642be76de9944 500 Pfam PF00361 Proton-conducting membrane transporter 118 340 1.0E-39 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17380 8b915f118f7684fb62349ac7393e691a 273 Pfam PF00005 ABC transporter 5 122 1.9E-17 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS17380 8b915f118f7684fb62349ac7393e691a 273 SUPERFAMILY SSF52540 6 257 2.17E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17380 8b915f118f7684fb62349ac7393e691a 273 Gene3D G3DSA:3.40.50.300 5 197 3.8E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17380 8b915f118f7684fb62349ac7393e691a 273 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 174 238 8.4E-22 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 GTHT12_RS17380 8b915f118f7684fb62349ac7393e691a 273 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 174 258 1.4E-27 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 GTHT12_RS17380 8b915f118f7684fb62349ac7393e691a 273 ProSitePatterns PS00211 ABC transporters family signature. 95 109 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS05990 95e3afded8aea20469bea8e399d4f577 433 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 11 411 2.1E-138 T 06-07-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 GTHT12_RS05990 95e3afded8aea20469bea8e399d4f577 433 Pfam PF00860 Permease family 15 386 8.9E-114 T 06-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 GTHT12_RS05990 95e3afded8aea20469bea8e399d4f577 433 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 334 354 - T 06-07-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 GTHT12_RS01775 da74a0adaca9cbc6d5fe155809c5a515 248 TIGRFAM TIGR03732 lanti_perm_MutE: lantibiotic protection ABC transporter permease subunit, MutE/EpiE family 3 247 8.3E-92 T 06-07-2017 IPR021205 Lantibiotic ABC transporter permease subunit, SpaE/MutE GTHT12_RS01775 da74a0adaca9cbc6d5fe155809c5a515 248 Pfam PF12730 ABC-2 family transporter protein 6 171 1.1E-8 T 06-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 GTHT12_RS13425 3ed2194dd5210672aaf0a54600682005 138 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 125 5.0E-34 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type GTHT12_RS13425 3ed2194dd5210672aaf0a54600682005 138 Pfam PF02082 Transcriptional regulator 1 82 8.4E-28 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type GTHT12_RS13425 3ed2194dd5210672aaf0a54600682005 138 Gene3D G3DSA:1.10.10.10 1 125 1.3E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS13425 3ed2194dd5210672aaf0a54600682005 138 SUPERFAMILY SSF46785 2 125 4.72E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS13425 3ed2194dd5210672aaf0a54600682005 138 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 06-07-2017 IPR030489 Transcription regulator Rrf2-type, conserved site GTHT12_RS14540 21140a89a90f763a932674085ff21d26 429 SUPERFAMILY SSF53098 141 307 1.59E-14 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS14540 21140a89a90f763a932674085ff21d26 429 Gene3D G3DSA:3.30.420.10 170 310 1.2E-13 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS14540 21140a89a90f763a932674085ff21d26 429 Pfam PF00665 Integrase core domain 141 268 8.2E-17 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS10715 8cabaac36b8a737435cacb7cb3455749 338 Gene3D G3DSA:3.40.50.2300 173 303 4.3E-49 T 06-07-2017 GTHT12_RS10715 8cabaac36b8a737435cacb7cb3455749 338 Pfam PF04392 ABC transporter substrate binding protein 44 334 1.3E-93 T 06-07-2017 IPR007487 ABC transporter, substrate-binding protein GTHT12_RS10715 8cabaac36b8a737435cacb7cb3455749 338 Gene3D G3DSA:3.40.50.2300 41 172 5.5E-54 T 06-07-2017 GTHT12_RS10715 8cabaac36b8a737435cacb7cb3455749 338 SUPERFAMILY SSF53822 41 235 7.86E-17 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS12715 2710059ce671c2cd43b289e74fcb2f1b 396 SUPERFAMILY SSF53067 81 384 3.73E-57 T 06-07-2017 GTHT12_RS12715 2710059ce671c2cd43b289e74fcb2f1b 396 Gene3D G3DSA:3.30.420.40 78 221 1.1E-42 T 06-07-2017 GTHT12_RS12715 2710059ce671c2cd43b289e74fcb2f1b 396 SUPERFAMILY SSF46785 8 73 6.55E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12715 2710059ce671c2cd43b289e74fcb2f1b 396 Gene3D G3DSA:1.10.10.10 8 76 6.3E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12715 2710059ce671c2cd43b289e74fcb2f1b 396 Gene3D G3DSA:3.30.420.40 222 363 8.0E-46 T 06-07-2017 GTHT12_RS12715 2710059ce671c2cd43b289e74fcb2f1b 396 Pfam PF00480 ROK family 83 382 1.6E-64 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 GTHT12_RS14975 17130c8a049e2c1b3a72087b5d1761ed 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 7.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS14975 17130c8a049e2c1b3a72087b5d1761ed 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 7.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS14975 17130c8a049e2c1b3a72087b5d1761ed 208 SUPERFAMILY SSF46689 8 75 5.99E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS14975 17130c8a049e2c1b3a72087b5d1761ed 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 56 1.2E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS14975 17130c8a049e2c1b3a72087b5d1761ed 208 Gene3D G3DSA:1.10.357.10 10 172 1.9E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 GTHT12_RS10240 dc896e73f8cc29cded81f15470ebcd31 469 Hamap MF_00675 Uronate isomerase [uxaC]. 2 465 51.387 T 06-07-2017 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 GTHT12_RS10240 dc896e73f8cc29cded81f15470ebcd31 469 Pfam PF02614 Glucuronate isomerase 1 463 1.8E-229 T 06-07-2017 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 GTHT12_RS10240 dc896e73f8cc29cded81f15470ebcd31 469 Gene3D G3DSA:3.20.20.140 138 465 3.9E-159 T 06-07-2017 GTHT12_RS10240 dc896e73f8cc29cded81f15470ebcd31 469 Gene3D G3DSA:3.20.20.140 4 44 3.9E-159 T 06-07-2017 GTHT12_RS10240 dc896e73f8cc29cded81f15470ebcd31 469 SUPERFAMILY SSF51556 3 463 1.81E-189 T 06-07-2017 IPR032466 Metal-dependent hydrolase GTHT12_RS10240 dc896e73f8cc29cded81f15470ebcd31 469 Gene3D G3DSA:1.10.2020.10 46 135 1.2E-42 T 06-07-2017 IPR023177 Uronate isomerase, domain 2 GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 GTHT12_RS10865 59ee00868f6839a1b82e4c7c8c6c7c6a 222 SMART SM00862 144 220 3.6E-25 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS10865 59ee00868f6839a1b82e4c7c8c6c7c6a 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 219 4.1E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS10865 59ee00868f6839a1b82e4c7c8c6c7c6a 222 Pfam PF00072 Response regulator receiver domain 4 110 3.3E-20 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS10865 59ee00868f6839a1b82e4c7c8c6c7c6a 222 SMART SM00448 2 110 2.6E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS10865 59ee00868f6839a1b82e4c7c8c6c7c6a 222 SUPERFAMILY SSF52172 3 175 1.12E-31 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS10865 59ee00868f6839a1b82e4c7c8c6c7c6a 222 Gene3D G3DSA:3.40.50.2300 3 119 1.8E-34 T 06-07-2017 GTHT12_RS10865 59ee00868f6839a1b82e4c7c8c6c7c6a 222 Gene3D G3DSA:1.10.10.10 120 221 1.1E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS03690 b68f1391d9de970d37ca7f1ddfac8e39 316 SUPERFAMILY SSF53800 3 308 5.4E-93 T 06-07-2017 GTHT12_RS03690 b68f1391d9de970d37ca7f1ddfac8e39 316 Pfam PF00762 Ferrochelatase 6 307 2.3E-88 T 06-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 GTHT12_RS03690 b68f1391d9de970d37ca7f1ddfac8e39 316 Gene3D G3DSA:3.40.50.1400 3 155 1.8E-41 T 06-07-2017 GTHT12_RS03690 b68f1391d9de970d37ca7f1ddfac8e39 316 TIGRFAM TIGR00109 hemH: ferrochelatase 3 308 3.8E-97 T 06-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 GTHT12_RS03690 b68f1391d9de970d37ca7f1ddfac8e39 316 ProSitePatterns PS00534 Ferrochelatase signature. 178 198 - T 06-07-2017 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 GTHT12_RS03690 b68f1391d9de970d37ca7f1ddfac8e39 316 Gene3D G3DSA:3.40.50.1400 156 287 1.2E-46 T 06-07-2017 GTHT12_RS03690 b68f1391d9de970d37ca7f1ddfac8e39 316 Hamap MF_00323 Ferrochelatase [hemH]. 4 308 32.349 T 06-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 GTHT12_RS18705 1e2f1ef10a71f92672136dd96681c663 540 SUPERFAMILY SSF53850 25 538 1.51E-96 T 06-07-2017 GTHT12_RS18705 1e2f1ef10a71f92672136dd96681c663 540 Gene3D G3DSA:3.40.190.10 67 171 5.8E-6 T 06-07-2017 GTHT12_RS18705 1e2f1ef10a71f92672136dd96681c663 540 Gene3D G3DSA:3.40.190.10 186 389 4.0E-72 T 06-07-2017 GTHT12_RS18705 1e2f1ef10a71f92672136dd96681c663 540 Gene3D G3DSA:3.40.190.10 487 538 4.0E-72 T 06-07-2017 GTHT12_RS18705 1e2f1ef10a71f92672136dd96681c663 540 Pfam PF01547 Bacterial extracellular solute-binding protein 70 383 1.8E-16 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 GTHT12_RS11615 664ba4dd288a06f606eb44da6ca5f22e 427 ProSitePatterns PS00104 EPSP synthase signature 1. 86 100 - T 06-07-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 GTHT12_RS11615 664ba4dd288a06f606eb44da6ca5f22e 427 Gene3D G3DSA:3.65.10.10 228 426 3.0E-56 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 GTHT12_RS11615 664ba4dd288a06f606eb44da6ca5f22e 427 Gene3D G3DSA:3.65.10.10 20 227 7.5E-58 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 GTHT12_RS11615 664ba4dd288a06f606eb44da6ca5f22e 427 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 12 426 6.8E-129 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 GTHT12_RS11615 664ba4dd288a06f606eb44da6ca5f22e 427 PIRSF PIRSF000505 1 427 1.4E-122 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 GTHT12_RS11615 664ba4dd288a06f606eb44da6ca5f22e 427 ProSitePatterns PS00885 EPSP synthase signature 2. 338 356 - T 06-07-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 GTHT12_RS11615 664ba4dd288a06f606eb44da6ca5f22e 427 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 6 423 2.4E-122 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 GTHT12_RS11615 664ba4dd288a06f606eb44da6ca5f22e 427 SUPERFAMILY SSF55205 4 426 2.29E-135 T 06-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 GTHT12_RS11615 664ba4dd288a06f606eb44da6ca5f22e 427 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 8 427 33.369 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 GTHT12_RS00230 9a97328ec2b00b6b062018b07a53a070 299 ProDom PD127708 YABG PROTEASE SPORULATION-SPECIFIC PEPTIDASE U57 BH0058 ORTHOLOG SPORE FAMILY B.SUBTILIS 1 280 7.0E-144 T 06-07-2017 IPR008764 Peptidase U57, YabG GTHT12_RS00230 9a97328ec2b00b6b062018b07a53a070 299 PIRSF PIRSF011575 2 289 1.2E-115 T 06-07-2017 IPR008764 Peptidase U57, YabG GTHT12_RS00230 9a97328ec2b00b6b062018b07a53a070 299 TIGRFAM TIGR02855 spore_yabG: sporulation peptidase YabG 4 286 2.0E-142 T 06-07-2017 IPR008764 Peptidase U57, YabG GTHT12_RS00230 9a97328ec2b00b6b062018b07a53a070 299 Pfam PF05582 YabG peptidase U57 4 285 3.6E-117 T 06-07-2017 IPR008764 Peptidase U57, YabG GTHT12_RS18215 e7848c2b9172a7dacc9c92501ecbf14c 238 SUPERFAMILY SSF53335 5 237 9.07E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS18215 e7848c2b9172a7dacc9c92501ecbf14c 238 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 214 28.267 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 GTHT12_RS18215 e7848c2b9172a7dacc9c92501ecbf14c 238 Gene3D G3DSA:3.40.50.150 2 237 1.5E-82 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS18215 e7848c2b9172a7dacc9c92501ecbf14c 238 PIRSF PIRSF003078 2 220 9.7E-55 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 GTHT12_RS18215 e7848c2b9172a7dacc9c92501ecbf14c 238 Pfam PF02527 rRNA small subunit methyltransferase G 23 201 1.5E-53 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 GTHT12_RS18215 e7848c2b9172a7dacc9c92501ecbf14c 238 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 25 214 1.1E-48 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 GTHT12_RS14335 bc7853ef45b915b30e9e09471b605be1 459 Hamap MF_00006 Argininosuccinate lyase [argH]. 3 454 45.537 T 06-07-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GTHT12_RS14335 bc7853ef45b915b30e9e09471b605be1 459 Gene3D G3DSA:1.20.200.10 108 374 3.3E-109 T 06-07-2017 GTHT12_RS14335 bc7853ef45b915b30e9e09471b605be1 459 SUPERFAMILY SSF48557 4 456 3.93E-154 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 GTHT12_RS14335 bc7853ef45b915b30e9e09471b605be1 459 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 9.7E-31 T 06-07-2017 IPR000362 Fumarate lyase family GTHT12_RS14335 bc7853ef45b915b30e9e09471b605be1 459 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 9.7E-31 T 06-07-2017 IPR000362 Fumarate lyase family GTHT12_RS14335 bc7853ef45b915b30e9e09471b605be1 459 PRINTS PR00149 Fumarate lyase superfamily signature 148 166 9.7E-31 T 06-07-2017 IPR000362 Fumarate lyase family GTHT12_RS14335 bc7853ef45b915b30e9e09471b605be1 459 PRINTS PR00149 Fumarate lyase superfamily signature 103 121 9.7E-31 T 06-07-2017 IPR000362 Fumarate lyase family GTHT12_RS14335 bc7853ef45b915b30e9e09471b605be1 459 Pfam PF00206 Lyase 7 301 4.7E-76 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal GTHT12_RS14335 bc7853ef45b915b30e9e09471b605be1 459 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 GTHT12_RS14335 bc7853ef45b915b30e9e09471b605be1 459 Gene3D G3DSA:1.10.275.10 2 107 7.0E-38 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal GTHT12_RS14335 bc7853ef45b915b30e9e09471b605be1 459 Gene3D G3DSA:1.10.40.30 375 432 3.7E-29 T 06-07-2017 GTHT12_RS14335 bc7853ef45b915b30e9e09471b605be1 459 TIGRFAM TIGR00838 argH: argininosuccinate lyase 4 456 7.6E-210 T 06-07-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GTHT12_RS14335 bc7853ef45b915b30e9e09471b605be1 459 PRINTS PR00145 Argininosuccinate lyase family signature 311 330 5.6E-70 T 06-07-2017 GTHT12_RS14335 bc7853ef45b915b30e9e09471b605be1 459 PRINTS PR00145 Argininosuccinate lyase family signature 102 124 5.6E-70 T 06-07-2017 GTHT12_RS14335 bc7853ef45b915b30e9e09471b605be1 459 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 5.6E-70 T 06-07-2017 GTHT12_RS14335 bc7853ef45b915b30e9e09471b605be1 459 PRINTS PR00145 Argininosuccinate lyase family signature 143 163 5.6E-70 T 06-07-2017 GTHT12_RS14335 bc7853ef45b915b30e9e09471b605be1 459 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 5.6E-70 T 06-07-2017 GTHT12_RS14335 bc7853ef45b915b30e9e09471b605be1 459 PRINTS PR00145 Argininosuccinate lyase family signature 194 210 5.6E-70 T 06-07-2017 GTHT12_RS14335 bc7853ef45b915b30e9e09471b605be1 459 Pfam PF14698 Argininosuccinate lyase C-terminal 364 432 9.3E-25 T 06-07-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 GTHT12_RS08200 7c19ba8e2d1f5def4b15634655103b11 402 SUPERFAMILY SSF53686 4 353 3.27E-101 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GTHT12_RS08200 7c19ba8e2d1f5def4b15634655103b11 402 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 21 399 3.8E-154 T 06-07-2017 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 GTHT12_RS08200 7c19ba8e2d1f5def4b15634655103b11 402 Pfam PF01842 ACT domain 333 393 3.0E-8 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 GTHT12_RS08200 7c19ba8e2d1f5def4b15634655103b11 402 Gene3D G3DSA:3.40.50.1100 69 321 3.1E-83 T 06-07-2017 GTHT12_RS08200 7c19ba8e2d1f5def4b15634655103b11 402 Gene3D G3DSA:3.30.70.260 325 388 4.0E-9 T 06-07-2017 GTHT12_RS08200 7c19ba8e2d1f5def4b15634655103b11 402 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 18 303 3.2E-84 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GTHT12_RS04735 2f071c0738e4026182be17426f884439 123 Pfam PF01638 HxlR-like helix-turn-helix 16 104 1.4E-39 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type GTHT12_RS04735 2f071c0738e4026182be17426f884439 123 SUPERFAMILY SSF46785 3 110 9.66E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS04735 2f071c0738e4026182be17426f884439 123 Gene3D G3DSA:1.10.10.10 2 106 1.1E-45 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS05515 17cca06f7e36a48fda06097e2702ce9f 290 Gene3D G3DSA:1.10.10.10 2 81 2.3E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS05515 17cca06f7e36a48fda06097e2702ce9f 290 SUPERFAMILY SSF46785 2 111 1.92E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS05515 17cca06f7e36a48fda06097e2702ce9f 290 Pfam PF03466 LysR substrate binding domain 88 286 1.1E-33 T 06-07-2017 IPR005119 LysR, substrate-binding GTHT12_RS05515 17cca06f7e36a48fda06097e2702ce9f 290 Gene3D G3DSA:3.40.190.10 82 186 3.6E-20 T 06-07-2017 GTHT12_RS05515 17cca06f7e36a48fda06097e2702ce9f 290 Gene3D G3DSA:3.40.190.10 187 253 1.7E-8 T 06-07-2017 GTHT12_RS05515 17cca06f7e36a48fda06097e2702ce9f 290 SUPERFAMILY SSF53850 88 289 1.81E-31 T 06-07-2017 GTHT12_RS05515 17cca06f7e36a48fda06097e2702ce9f 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 3.3E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GTHT12_RS07460 cc2fd1875275b37710f6d8cd33cbe374 478 Pfam PF00390 Malic enzyme, N-terminal domain 94 226 1.7E-31 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 GTHT12_RS07460 cc2fd1875275b37710f6d8cd33cbe374 478 SUPERFAMILY SSF51735 238 471 1.49E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS07460 cc2fd1875275b37710f6d8cd33cbe374 478 SUPERFAMILY SSF53223 87 236 3.09E-58 T 06-07-2017 GTHT12_RS07460 cc2fd1875275b37710f6d8cd33cbe374 478 SMART SM00919 238 460 1.8E-128 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 GTHT12_RS07460 cc2fd1875275b37710f6d8cd33cbe374 478 ProSitePatterns PS00331 Malic enzymes signature. 234 250 - T 06-07-2017 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 GTHT12_RS07460 cc2fd1875275b37710f6d8cd33cbe374 478 PIRSF PIRSF000106 3 473 4.1E-102 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 GTHT12_RS07460 cc2fd1875275b37710f6d8cd33cbe374 478 SMART SM01274 93 226 8.8E-88 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 GTHT12_RS07460 cc2fd1875275b37710f6d8cd33cbe374 478 Pfam PF03949 Malic enzyme, NAD binding domain 240 459 7.8E-26 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 GTHT12_RS07460 cc2fd1875275b37710f6d8cd33cbe374 478 Gene3D G3DSA:3.40.50.10380 93 235 7.5E-56 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 GTHT12_RS07460 cc2fd1875275b37710f6d8cd33cbe374 478 Gene3D G3DSA:3.40.50.720 236 468 1.0E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS06430 2e9e80d7ae0872cb9e005f0e10f00168 371 Pfam PF00448 SRP54-type protein, GTPase domain 177 366 2.0E-42 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GTHT12_RS06430 2e9e80d7ae0872cb9e005f0e10f00168 371 Gene3D G3DSA:1.20.120.140 113 186 4.4E-5 T 06-07-2017 GTHT12_RS06430 2e9e80d7ae0872cb9e005f0e10f00168 371 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 1 263 2.8E-73 T 06-07-2017 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 GTHT12_RS06430 2e9e80d7ae0872cb9e005f0e10f00168 371 SMART SM00382 175 322 3.8E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS06430 2e9e80d7ae0872cb9e005f0e10f00168 371 Gene3D G3DSA:3.40.50.300 187 367 3.0E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06430 2e9e80d7ae0872cb9e005f0e10f00168 371 SMART SM00962 176 367 3.8E-62 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 GTHT12_RS06430 2e9e80d7ae0872cb9e005f0e10f00168 371 SUPERFAMILY SSF52540 173 367 2.8E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07835 87352cfeeef57a523b9e4b09ff6969e0 369 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 14 167 3.1E-31 T 06-07-2017 IPR017516 AbrB duplication GTHT12_RS07835 87352cfeeef57a523b9e4b09ff6969e0 369 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 196 350 1.6E-36 T 06-07-2017 IPR017516 AbrB duplication GTHT12_RS07835 87352cfeeef57a523b9e4b09ff6969e0 369 Pfam PF05145 Putative ammonia monooxygenase 36 350 2.0E-75 T 06-07-2017 IPR007820 AbrB family GO:0010468|GO:0016021 GTHT12_RS07835 87352cfeeef57a523b9e4b09ff6969e0 369 PIRSF PIRSF038991 2 360 4.0E-101 T 06-07-2017 IPR007820 AbrB family GO:0010468|GO:0016021 GTHT12_RS16885 1571e466d2222153e2004740c249e4a0 565 Gene3D G3DSA:2.60.40.1180 502 562 3.3E-8 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta GTHT12_RS16885 1571e466d2222153e2004740c249e4a0 565 SUPERFAMILY SSF51445 402 536 1.25E-77 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS16885 1571e466d2222153e2004740c249e4a0 565 SUPERFAMILY SSF51445 53 360 1.25E-77 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS16885 1571e466d2222153e2004740c249e4a0 565 Gene3D G3DSA:3.90.400.10 138 206 1.9E-21 T 06-07-2017 GTHT12_RS16885 1571e466d2222153e2004740c249e4a0 565 Pfam PF00128 Alpha amylase, catalytic domain 86 341 5.4E-20 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GTHT12_RS16885 1571e466d2222153e2004740c249e4a0 565 Gene3D G3DSA:3.20.20.80 212 486 3.4E-97 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS16885 1571e466d2222153e2004740c249e4a0 565 Gene3D G3DSA:3.20.20.80 50 137 3.4E-97 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS16885 1571e466d2222153e2004740c249e4a0 565 PIRSF PIRSF003059 7 563 4.1E-193 T 06-07-2017 IPR016377 Sucrose phosphorylase GO:0005985|GO:0009018 KEGG: 00500+2.4.1.7|MetaCyc: PWY-5384 GTHT12_RS16885 1571e466d2222153e2004740c249e4a0 565 SMART SM00642 31 484 7.6E-6 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GTHT12_RS06465 b3705869246f8d0c015ddcd35dc0ed98 253 Pfam PF04539 Sigma-70 region 3 110 185 1.1E-9 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS06465 b3705869246f8d0c015ddcd35dc0ed98 253 SUPERFAMILY SSF88659 174 250 1.74E-18 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS06465 b3705869246f8d0c015ddcd35dc0ed98 253 SUPERFAMILY SSF88659 103 172 6.35E-15 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS06465 b3705869246f8d0c015ddcd35dc0ed98 253 Pfam PF04542 Sigma-70 region 2 30 102 7.3E-15 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS06465 b3705869246f8d0c015ddcd35dc0ed98 253 Gene3D G3DSA:1.10.10.10 196 249 5.1E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS06465 b3705869246f8d0c015ddcd35dc0ed98 253 Pfam PF04545 Sigma-70, region 4 199 247 2.6E-15 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS06465 b3705869246f8d0c015ddcd35dc0ed98 253 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 30 247 1.3E-77 T 06-07-2017 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS06465 b3705869246f8d0c015ddcd35dc0ed98 253 PIRSF PIRSF000770 21 253 1.8E-41 T 06-07-2017 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 GTHT12_RS06465 b3705869246f8d0c015ddcd35dc0ed98 253 PRINTS PR00046 Major sigma-70 factor signature 219 234 9.3E-11 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS06465 b3705869246f8d0c015ddcd35dc0ed98 253 PRINTS PR00046 Major sigma-70 factor signature 202 214 9.3E-11 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS06465 b3705869246f8d0c015ddcd35dc0ed98 253 PRINTS PR00046 Major sigma-70 factor signature 57 70 9.3E-11 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS06465 b3705869246f8d0c015ddcd35dc0ed98 253 PRINTS PR00046 Major sigma-70 factor signature 81 89 9.3E-11 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS06465 b3705869246f8d0c015ddcd35dc0ed98 253 PRINTS PR00046 Major sigma-70 factor signature 234 245 9.3E-11 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS06465 b3705869246f8d0c015ddcd35dc0ed98 253 Gene3D G3DSA:1.10.601.10 10 95 2.0E-16 T 06-07-2017 GTHT12_RS06465 b3705869246f8d0c015ddcd35dc0ed98 253 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 247 1.7E-29 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS06465 b3705869246f8d0c015ddcd35dc0ed98 253 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 57 70 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS06465 b3705869246f8d0c015ddcd35dc0ed98 253 SUPERFAMILY SSF88946 9 102 3.01E-25 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS06465 b3705869246f8d0c015ddcd35dc0ed98 253 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 219 245 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS06465 b3705869246f8d0c015ddcd35dc0ed98 253 Gene3D G3DSA:1.10.10.10 102 148 2.1E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS07040 d6780c1d8431f82756033f9d85f7d51a 274 Gene3D G3DSA:1.20.1080.10 2 234 2.9E-87 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 GTHT12_RS07040 d6780c1d8431f82756033f9d85f7d51a 274 SUPERFAMILY SSF81338 2 234 1.44E-74 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 GTHT12_RS07040 d6780c1d8431f82756033f9d85f7d51a 274 TIGRFAM TIGR00861 MIP: MIP family channel proteins 7 230 3.1E-66 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 GTHT12_RS07040 d6780c1d8431f82756033f9d85f7d51a 274 PRINTS PR00783 Major intrinsic protein family signature 2 21 4.5E-52 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 GTHT12_RS07040 d6780c1d8431f82756033f9d85f7d51a 274 PRINTS PR00783 Major intrinsic protein family signature 81 100 4.5E-52 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 GTHT12_RS07040 d6780c1d8431f82756033f9d85f7d51a 274 PRINTS PR00783 Major intrinsic protein family signature 213 233 4.5E-52 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 GTHT12_RS07040 d6780c1d8431f82756033f9d85f7d51a 274 PRINTS PR00783 Major intrinsic protein family signature 136 154 4.5E-52 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 GTHT12_RS07040 d6780c1d8431f82756033f9d85f7d51a 274 PRINTS PR00783 Major intrinsic protein family signature 44 68 4.5E-52 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 GTHT12_RS07040 d6780c1d8431f82756033f9d85f7d51a 274 PRINTS PR00783 Major intrinsic protein family signature 166 188 4.5E-52 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 GTHT12_RS07040 d6780c1d8431f82756033f9d85f7d51a 274 ProSitePatterns PS00221 MIP family signature. 62 70 - T 06-07-2017 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 GTHT12_RS07040 d6780c1d8431f82756033f9d85f7d51a 274 Pfam PF00230 Major intrinsic protein 4 230 9.5E-52 T 06-07-2017 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 GTHT12_RS14980 09701cf868432c64f2d38d5198580e02 300 SUPERFAMILY SSF53335 6 299 8.72E-59 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS14980 09701cf868432c64f2d38d5198580e02 300 Gene3D G3DSA:3.40.50.150 83 270 6.2E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS14980 09701cf868432c64f2d38d5198580e02 300 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 8 255 7.2E-43 T 06-07-2017 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 GTHT12_RS14980 09701cf868432c64f2d38d5198580e02 300 Pfam PF04072 Leucine carboxyl methyltransferase 10 204 2.9E-44 T 06-07-2017 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 GTHT12_RS11930 1b53bd22b191bdf1c6beea449374829f 162 Pfam PF12822 Protein of unknown function (DUF3816) 3 148 1.3E-8 T 06-07-2017 IPR024529 ECF transporter, substrate-specific component GO:0005215 GTHT12_RS03570 7aa66af1b9cd86b12d33a22efadd3e06 356 Gene3D G3DSA:3.30.1490.20 128 173 2.1E-5 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GTHT12_RS03570 7aa66af1b9cd86b12d33a22efadd3e06 356 SUPERFAMILY SSF56059 123 328 8.91E-15 T 06-07-2017 GTHT12_RS03570 7aa66af1b9cd86b12d33a22efadd3e06 356 Pfam PF14398 YheC/D like ATP-grasp 100 349 8.6E-64 T 06-07-2017 IPR026838 Endospore coat-associated protein YheC/D GTHT12_RS01315 3d78286a72b87891cdc8fcd516f70a9e 384 Gene3D G3DSA:3.20.20.10 14 222 5.3E-74 T 06-07-2017 IPR029066 PLP-binding barrel GTHT12_RS01315 3d78286a72b87891cdc8fcd516f70a9e 384 SUPERFAMILY SSF50621 239 379 9.07E-52 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 GTHT12_RS01315 3d78286a72b87891cdc8fcd516f70a9e 384 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 36 46 - T 06-07-2017 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GTHT12_RS01315 3d78286a72b87891cdc8fcd516f70a9e 384 TIGRFAM TIGR00492 alr: alanine racemase 6 368 3.3E-125 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GTHT12_RS01315 3d78286a72b87891cdc8fcd516f70a9e 384 Pfam PF01168 Alanine racemase, N-terminal domain 12 229 1.3E-67 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GTHT12_RS01315 3d78286a72b87891cdc8fcd516f70a9e 384 Gene3D G3DSA:2.40.37.10 223 377 1.2E-58 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 GTHT12_RS01315 3d78286a72b87891cdc8fcd516f70a9e 384 PRINTS PR00992 Alanine racemase signature 260 275 2.7E-74 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GTHT12_RS01315 3d78286a72b87891cdc8fcd516f70a9e 384 PRINTS PR00992 Alanine racemase signature 31 47 2.7E-74 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GTHT12_RS01315 3d78286a72b87891cdc8fcd516f70a9e 384 PRINTS PR00992 Alanine racemase signature 351 364 2.7E-74 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GTHT12_RS01315 3d78286a72b87891cdc8fcd516f70a9e 384 PRINTS PR00992 Alanine racemase signature 162 173 2.7E-74 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GTHT12_RS01315 3d78286a72b87891cdc8fcd516f70a9e 384 PRINTS PR00992 Alanine racemase signature 67 85 2.7E-74 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GTHT12_RS01315 3d78286a72b87891cdc8fcd516f70a9e 384 PRINTS PR00992 Alanine racemase signature 127 139 2.7E-74 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GTHT12_RS01315 3d78286a72b87891cdc8fcd516f70a9e 384 PRINTS PR00992 Alanine racemase signature 297 314 2.7E-74 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GTHT12_RS01315 3d78286a72b87891cdc8fcd516f70a9e 384 PRINTS PR00992 Alanine racemase signature 277 292 2.7E-74 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GTHT12_RS01315 3d78286a72b87891cdc8fcd516f70a9e 384 PRINTS PR00992 Alanine racemase signature 202 229 2.7E-74 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GTHT12_RS01315 3d78286a72b87891cdc8fcd516f70a9e 384 SMART SM01005 244 369 1.6E-72 T 06-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GTHT12_RS01315 3d78286a72b87891cdc8fcd516f70a9e 384 Pfam PF00842 Alanine racemase, C-terminal domain 245 367 1.0E-41 T 06-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GTHT12_RS01315 3d78286a72b87891cdc8fcd516f70a9e 384 Hamap MF_01201 Alanine racemase. 5 369 35.6 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GTHT12_RS01315 3d78286a72b87891cdc8fcd516f70a9e 384 SUPERFAMILY SSF51419 12 235 8.72E-67 T 06-07-2017 IPR029066 PLP-binding barrel GTHT12_RS17630 71cb345026e480cba0cf767691665a8e 185 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 10 185 14.167 T 06-07-2017 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 GTHT12_RS17630 71cb345026e480cba0cf767691665a8e 185 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 15 82 7.9E-10 T 06-07-2017 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 GTHT12_RS17630 71cb345026e480cba0cf767691665a8e 185 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 13 93 6.6E-30 T 06-07-2017 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 GTHT12_RS13970 41aab394eb72fcfefe56e32845aa50df 374 Gene3D G3DSA:3.20.20.30 1 251 2.2E-110 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 GTHT12_RS13970 41aab394eb72fcfefe56e32845aa50df 374 Gene3D G3DSA:3.20.20.30 285 348 2.2E-110 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 GTHT12_RS13970 41aab394eb72fcfefe56e32845aa50df 374 SUPERFAMILY SSF51679 1 347 1.57E-102 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 GTHT12_RS13970 41aab394eb72fcfefe56e32845aa50df 374 Hamap MF_01229 Alkanesulfonate monooxygenase [ssuD]. 2 373 69.046 T 06-07-2017 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 GTHT12_RS13970 41aab394eb72fcfefe56e32845aa50df 374 Pfam PF00296 Luciferase-like monooxygenase 1 323 2.7E-94 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 GTHT12_RS13970 41aab394eb72fcfefe56e32845aa50df 374 TIGRFAM TIGR03565 alk_sulf_monoox: alkanesulfonate monooxygenase, FMNH(2)-dependent 2 347 7.7E-189 T 06-07-2017 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 GTHT12_RS08195 7fb4ae6006ffc1ebc02592ba1fd4361a 387 Pfam PF07690 Major Facilitator Superfamily 9 344 3.1E-58 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS08195 7fb4ae6006ffc1ebc02592ba1fd4361a 387 PRINTS PR01035 Tetracycline resistance protein signature 72 96 6.5E-30 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS08195 7fb4ae6006ffc1ebc02592ba1fd4361a 387 PRINTS PR01035 Tetracycline resistance protein signature 130 152 6.5E-30 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS08195 7fb4ae6006ffc1ebc02592ba1fd4361a 387 PRINTS PR01035 Tetracycline resistance protein signature 158 178 6.5E-30 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS08195 7fb4ae6006ffc1ebc02592ba1fd4361a 387 PRINTS PR01035 Tetracycline resistance protein signature 240 260 6.5E-30 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS08195 7fb4ae6006ffc1ebc02592ba1fd4361a 387 PRINTS PR01035 Tetracycline resistance protein signature 15 31 6.5E-30 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS08195 7fb4ae6006ffc1ebc02592ba1fd4361a 387 PRINTS PR01035 Tetracycline resistance protein signature 328 351 6.5E-30 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS08195 7fb4ae6006ffc1ebc02592ba1fd4361a 387 PRINTS PR01035 Tetracycline resistance protein signature 268 289 6.5E-30 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS08195 7fb4ae6006ffc1ebc02592ba1fd4361a 387 Gene3D G3DSA:1.20.1250.20 203 377 7.3E-21 T 06-07-2017 GTHT12_RS08195 7fb4ae6006ffc1ebc02592ba1fd4361a 387 Gene3D G3DSA:1.20.1250.20 2 183 4.9E-49 T 06-07-2017 GTHT12_RS08195 7fb4ae6006ffc1ebc02592ba1fd4361a 387 SUPERFAMILY SSF103473 2 377 1.22E-73 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS06970 d6520a265185e4b08db23395ccf27df0 103 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 6 99 3.1E-36 T 06-07-2017 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 GTHT12_RS06970 d6520a265185e4b08db23395ccf27df0 103 SUPERFAMILY SSF46973 2 100 8.37E-36 T 06-07-2017 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 GTHT12_RS06970 d6520a265185e4b08db23395ccf27df0 103 PIRSF PIRSF000699 1 103 4.4E-39 T 06-07-2017 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 GTHT12_RS06970 d6520a265185e4b08db23395ccf27df0 103 Gene3D G3DSA:1.20.58.80 1 101 1.8E-42 T 06-07-2017 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 GTHT12_RS06970 d6520a265185e4b08db23395ccf27df0 103 TIGRFAM TIGR00823 EIIA-LAC: PTS system, lactose-specific IIa component 3 100 1.0E-41 T 06-07-2017 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 GTHT12_RS06185 867d24ae3e5eee986864e812bcb3d7d1 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 185 3.2E-6 T 06-07-2017 GTHT12_RS06185 867d24ae3e5eee986864e812bcb3d7d1 247 Gene3D G3DSA:3.40.50.720 2 246 5.3E-102 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS06185 867d24ae3e5eee986864e812bcb3d7d1 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 244 3.9E-77 T 06-07-2017 GTHT12_RS06185 867d24ae3e5eee986864e812bcb3d7d1 247 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 7 245 4.1E-111 T 06-07-2017 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 GTHT12_RS06185 867d24ae3e5eee986864e812bcb3d7d1 247 SUPERFAMILY SSF51735 3 246 2.17E-98 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS06185 867d24ae3e5eee986864e812bcb3d7d1 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.7E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS06185 867d24ae3e5eee986864e812bcb3d7d1 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.7E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS06185 867d24ae3e5eee986864e812bcb3d7d1 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.7E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS06185 867d24ae3e5eee986864e812bcb3d7d1 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 7.3E-52 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS06185 867d24ae3e5eee986864e812bcb3d7d1 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 7.3E-52 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS06185 867d24ae3e5eee986864e812bcb3d7d1 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 7.3E-52 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS06185 867d24ae3e5eee986864e812bcb3d7d1 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 7.3E-52 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS06185 867d24ae3e5eee986864e812bcb3d7d1 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 7.3E-52 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS06185 867d24ae3e5eee986864e812bcb3d7d1 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 7.3E-52 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS06185 867d24ae3e5eee986864e812bcb3d7d1 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GTHT12_RS13565 9e0c62d7499e33912cc25ba9c6f6b905 246 SUPERFAMILY SSF52402 1 245 8.82E-76 T 06-07-2017 GTHT12_RS13565 9e0c62d7499e33912cc25ba9c6f6b905 246 Gene3D G3DSA:3.40.50.620 1 243 1.4E-76 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS13565 9e0c62d7499e33912cc25ba9c6f6b905 246 TIGRFAM TIGR00552 nadE: NAD+ synthetase 2 239 9.0E-76 T 06-07-2017 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 GTHT12_RS13565 9e0c62d7499e33912cc25ba9c6f6b905 246 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 1 243 32.295 T 06-07-2017 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 GTHT12_RS13565 9e0c62d7499e33912cc25ba9c6f6b905 246 Pfam PF02540 NAD synthase 5 240 4.6E-71 T 06-07-2017 IPR022310 NAD/GMP synthase GTHT12_RS05700 30cc0d85d504b2374a41c02a6cd24c6d 622 Gene3D G3DSA:1.10.287.70 548 595 7.6E-4 T 06-07-2017 GTHT12_RS05700 30cc0d85d504b2374a41c02a6cd24c6d 622 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 25 469 6.6E-148 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05700 30cc0d85d504b2374a41c02a6cd24c6d 622 Gene3D G3DSA:1.20.210.10 12 540 4.1E-190 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05700 30cc0d85d504b2374a41c02a6cd24c6d 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 63 86 5.0E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05700 30cc0d85d504b2374a41c02a6cd24c6d 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 16 41 5.0E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05700 30cc0d85d504b2374a41c02a6cd24c6d 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 192 211 5.0E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05700 30cc0d85d504b2374a41c02a6cd24c6d 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 90 114 5.0E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05700 30cc0d85d504b2374a41c02a6cd24c6d 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 132 144 5.0E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05700 30cc0d85d504b2374a41c02a6cd24c6d 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 243 264 5.0E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05700 30cc0d85d504b2374a41c02a6cd24c6d 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 313 334 5.0E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05700 30cc0d85d504b2374a41c02a6cd24c6d 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 426 447 5.0E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05700 30cc0d85d504b2374a41c02a6cd24c6d 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 376 395 5.0E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05700 30cc0d85d504b2374a41c02a6cd24c6d 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 289 304 5.0E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05700 30cc0d85d504b2374a41c02a6cd24c6d 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 163 181 5.0E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05700 30cc0d85d504b2374a41c02a6cd24c6d 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 366 5.0E-104 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05700 30cc0d85d504b2374a41c02a6cd24c6d 622 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 17 520 1.5E-204 T 06-07-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 GTHT12_RS05700 30cc0d85d504b2374a41c02a6cd24c6d 622 SUPERFAMILY SSF81442 14 522 2.09E-175 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05700 30cc0d85d504b2374a41c02a6cd24c6d 622 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 245 299 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05405 ade5f4238ad66cd6f764e9af82c8731f 261 SUPERFAMILY SSF51735 7 258 8.56E-83 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS05405 ade5f4238ad66cd6f764e9af82c8731f 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 257 5.4E-61 T 06-07-2017 GTHT12_RS05405 ade5f4238ad66cd6f764e9af82c8731f 261 Gene3D G3DSA:3.40.50.720 3 258 2.0E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS05405 ade5f4238ad66cd6f764e9af82c8731f 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 5.7E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05405 ade5f4238ad66cd6f764e9af82c8731f 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 5.7E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05405 ade5f4238ad66cd6f764e9af82c8731f 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 5.7E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05405 ade5f4238ad66cd6f764e9af82c8731f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 3.1E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05405 ade5f4238ad66cd6f764e9af82c8731f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 3.1E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05405 ade5f4238ad66cd6f764e9af82c8731f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 3.1E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05405 ade5f4238ad66cd6f764e9af82c8731f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 3.1E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05405 ade5f4238ad66cd6f764e9af82c8731f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.1E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS05405 ade5f4238ad66cd6f764e9af82c8731f 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 3.1E-36 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS07390 058da3d92117bfbd36838945761650e9 328 SUPERFAMILY SSF51735 119 291 1.18E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS07390 058da3d92117bfbd36838945761650e9 328 SUPERFAMILY SSF50129 4 145 3.96E-42 T 06-07-2017 IPR011032 GroES-like GTHT12_RS07390 058da3d92117bfbd36838945761650e9 328 Gene3D G3DSA:3.90.180.10 15 134 3.5E-12 T 06-07-2017 IPR011032 GroES-like GTHT12_RS07390 058da3d92117bfbd36838945761650e9 328 Gene3D G3DSA:3.40.50.720 135 294 7.0E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS07390 058da3d92117bfbd36838945761650e9 328 SMART SM00829 19 325 1.0E-5 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 GTHT12_RS07390 058da3d92117bfbd36838945761650e9 328 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 5 327 9.3E-144 T 06-07-2017 IPR014188 Acrylyl-CoA reductase AcuI GTHT12_RS07390 058da3d92117bfbd36838945761650e9 328 Pfam PF00107 Zinc-binding dehydrogenase 161 270 4.0E-16 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 GTHT12_RS13670 fb6a0d7cf3bb766730c98b581a8a02d9 340 SUPERFAMILY SSF53067 147 330 1.07E-50 T 06-07-2017 GTHT12_RS13670 fb6a0d7cf3bb766730c98b581a8a02d9 340 Pfam PF06723 MreB/Mbl protein 7 332 2.9E-152 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 GTHT12_RS13670 fb6a0d7cf3bb766730c98b581a8a02d9 340 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 184 204 8.7E-62 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 GTHT12_RS13670 fb6a0d7cf3bb766730c98b581a8a02d9 340 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 297 323 8.7E-62 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 GTHT12_RS13670 fb6a0d7cf3bb766730c98b581a8a02d9 340 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 44 62 8.7E-62 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 GTHT12_RS13670 fb6a0d7cf3bb766730c98b581a8a02d9 340 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 64 87 8.7E-62 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 GTHT12_RS13670 fb6a0d7cf3bb766730c98b581a8a02d9 340 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 129 148 8.7E-62 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 GTHT12_RS13670 fb6a0d7cf3bb766730c98b581a8a02d9 340 Gene3D G3DSA:3.30.420.40 260 314 2.5E-37 T 06-07-2017 GTHT12_RS13670 fb6a0d7cf3bb766730c98b581a8a02d9 340 Gene3D G3DSA:3.30.420.40 157 183 2.5E-37 T 06-07-2017 GTHT12_RS13670 fb6a0d7cf3bb766730c98b581a8a02d9 340 Gene3D G3DSA:3.90.640.10 184 255 7.0E-33 T 06-07-2017 GTHT12_RS13670 fb6a0d7cf3bb766730c98b581a8a02d9 340 SUPERFAMILY SSF53067 7 144 2.16E-38 T 06-07-2017 GTHT12_RS13670 fb6a0d7cf3bb766730c98b581a8a02d9 340 Gene3D G3DSA:3.30.420.40 7 156 3.3E-45 T 06-07-2017 GTHT12_RS13670 fb6a0d7cf3bb766730c98b581a8a02d9 340 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 6 333 5.5E-161 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 GTHT12_RS00990 47c8ab66bb53d1ee46613aed458e7627 312 Pfam PF00665 Integrase core domain 137 256 3.5E-25 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS00990 47c8ab66bb53d1ee46613aed458e7627 312 Gene3D G3DSA:3.30.420.10 132 293 9.4E-35 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS00990 47c8ab66bb53d1ee46613aed458e7627 312 SUPERFAMILY SSF53098 138 299 5.18E-34 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS00990 47c8ab66bb53d1ee46613aed458e7627 312 Pfam PF13276 HTH-like domain 76 122 1.1E-11 T 06-07-2017 IPR025948 HTH-like domain GTHT12_RS12160 ad2f83ea3fb00cac2cc8fff701b5a028 142 Pfam PF03862 SpoVA protein 23 139 2.3E-27 T 06-07-2017 IPR005562 SpoVA GTHT12_RS02800 4dcf46ec9e63adaec5319ab26f8a29d8 210 Pfam PF00072 Response regulator receiver domain 4 115 2.1E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS02800 4dcf46ec9e63adaec5319ab26f8a29d8 210 SMART SM00421 146 203 1.5E-28 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS02800 4dcf46ec9e63adaec5319ab26f8a29d8 210 SUPERFAMILY SSF46894 136 209 1.02E-25 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GTHT12_RS02800 4dcf46ec9e63adaec5319ab26f8a29d8 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 1.0E-22 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS02800 4dcf46ec9e63adaec5319ab26f8a29d8 210 Gene3D G3DSA:1.10.10.10 122 209 1.4E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS02800 4dcf46ec9e63adaec5319ab26f8a29d8 210 Gene3D G3DSA:3.40.50.2300 2 121 3.8E-34 T 06-07-2017 GTHT12_RS02800 4dcf46ec9e63adaec5319ab26f8a29d8 210 SMART SM00448 2 115 9.9E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS02800 4dcf46ec9e63adaec5319ab26f8a29d8 210 SUPERFAMILY SSF52172 2 133 4.84E-32 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS02800 4dcf46ec9e63adaec5319ab26f8a29d8 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 3.0E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS02800 4dcf46ec9e63adaec5319ab26f8a29d8 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 3.0E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS02800 4dcf46ec9e63adaec5319ab26f8a29d8 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 3.0E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS18805 b049858c62aa7ffdc93b0235d8a31d9d 165 TIGRFAM TIGR02950 SigM_subfam: RNA polymerase sigma factor, SigM family 2 154 8.9E-56 T 06-07-2017 IPR014296 RNA polymerase sigma-M, bacillaceae GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS18805 b049858c62aa7ffdc93b0235d8a31d9d 165 Gene3D G3DSA:1.10.1740.10 2 73 2.8E-21 T 06-07-2017 GTHT12_RS18805 b049858c62aa7ffdc93b0235d8a31d9d 165 SUPERFAMILY SSF88946 2 76 7.46E-20 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS18805 b049858c62aa7ffdc93b0235d8a31d9d 165 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 2 154 1.2E-20 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS18805 b049858c62aa7ffdc93b0235d8a31d9d 165 Pfam PF08281 Sigma-70, region 4 100 150 2.1E-10 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS18805 b049858c62aa7ffdc93b0235d8a31d9d 165 Pfam PF04542 Sigma-70 region 2 2 66 5.2E-14 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS18805 b049858c62aa7ffdc93b0235d8a31d9d 165 Gene3D G3DSA:1.10.10.10 93 157 5.2E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS18805 b049858c62aa7ffdc93b0235d8a31d9d 165 SUPERFAMILY SSF88659 87 155 2.99E-11 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS02685 f38101a1e697049742201919b5af8c79 540 Pfam PF01609 Transposase DDE domain 221 474 1.0E-16 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 GTHT12_RS02685 f38101a1e697049742201919b5af8c79 540 SUPERFAMILY SSF53098 411 486 1.59E-13 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS02685 f38101a1e697049742201919b5af8c79 540 SUPERFAMILY SSF53098 253 320 1.59E-13 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS17990 f38101a1e697049742201919b5af8c79 540 Pfam PF01609 Transposase DDE domain 221 474 1.0E-16 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 GTHT12_RS17990 f38101a1e697049742201919b5af8c79 540 SUPERFAMILY SSF53098 411 486 1.59E-13 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS17990 f38101a1e697049742201919b5af8c79 540 SUPERFAMILY SSF53098 253 320 1.59E-13 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS10090 f38101a1e697049742201919b5af8c79 540 Pfam PF01609 Transposase DDE domain 221 474 1.0E-16 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 GTHT12_RS10090 f38101a1e697049742201919b5af8c79 540 SUPERFAMILY SSF53098 411 486 1.59E-13 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS10090 f38101a1e697049742201919b5af8c79 540 SUPERFAMILY SSF53098 253 320 1.59E-13 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS17040 f38101a1e697049742201919b5af8c79 540 Pfam PF01609 Transposase DDE domain 221 474 1.0E-16 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 GTHT12_RS17040 f38101a1e697049742201919b5af8c79 540 SUPERFAMILY SSF53098 411 486 1.59E-13 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS17040 f38101a1e697049742201919b5af8c79 540 SUPERFAMILY SSF53098 253 320 1.59E-13 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS04715 f38101a1e697049742201919b5af8c79 540 Pfam PF01609 Transposase DDE domain 221 474 1.0E-16 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 GTHT12_RS04715 f38101a1e697049742201919b5af8c79 540 SUPERFAMILY SSF53098 411 486 1.59E-13 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS04715 f38101a1e697049742201919b5af8c79 540 SUPERFAMILY SSF53098 253 320 1.59E-13 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS12260 6145e1a2af88584cc3fda47b2d80b06c 79 ProDom PD058987 CYTOSOLIC YQKC 22 79 1.0E-25 T 06-07-2017 IPR020157 Uncharacterised protein family YqkC GTHT12_RS12260 6145e1a2af88584cc3fda47b2d80b06c 79 Pfam PF10827 Protein of unknown function (DUF2552) 1 79 4.7E-45 T 06-07-2017 IPR020157 Uncharacterised protein family YqkC GTHT12_RS09765 5ae99ead4215b838d7e1134b27d2f02e 103 SUPERFAMILY SSF52794 1 102 1.78E-35 T 06-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 GTHT12_RS09765 5ae99ead4215b838d7e1134b27d2f02e 103 Gene3D G3DSA:3.40.50.270 1 102 1.2E-36 T 06-07-2017 GTHT12_RS09765 5ae99ead4215b838d7e1134b27d2f02e 103 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 95 1.4E-21 T 06-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 GTHT12_RS04580 ef2fc7b4629dbba74be03923630a0b1d 392 Gene3D G3DSA:3.90.1150.10 248 381 2.9E-48 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS04580 ef2fc7b4629dbba74be03923630a0b1d 392 PIRSF PIRSF001434 1 384 1.4E-146 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 GTHT12_RS04580 ef2fc7b4629dbba74be03923630a0b1d 392 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 380 2.1E-150 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 GTHT12_RS04580 ef2fc7b4629dbba74be03923630a0b1d 392 Gene3D G3DSA:3.40.640.10 6 247 2.8E-97 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS04580 ef2fc7b4629dbba74be03923630a0b1d 392 SUPERFAMILY SSF53383 22 381 1.93E-114 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS04580 ef2fc7b4629dbba74be03923630a0b1d 392 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 191 205 - T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 GTHT12_RS13070 e1640cada05906d8bcec8d8aa8718055 395 PIRSF PIRSF029895 1 395 7.0E-173 T 06-07-2017 IPR010690 Putative stage IV sporulation YqfD GTHT12_RS13070 e1640cada05906d8bcec8d8aa8718055 395 TIGRFAM TIGR02876 spore_yqfD: sporulation protein YqfD 5 387 4.0E-147 T 06-07-2017 IPR010690 Putative stage IV sporulation YqfD GTHT12_RS13070 e1640cada05906d8bcec8d8aa8718055 395 Pfam PF06898 Putative stage IV sporulation protein YqfD 9 385 2.4E-129 T 06-07-2017 IPR010690 Putative stage IV sporulation YqfD GTHT12_RS16295 805f855315765e60dc8e997d565dfb9a 383 Pfam PF07730 Histidine kinase 181 249 5.8E-15 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 GTHT12_RS16295 805f855315765e60dc8e997d565dfb9a 383 PIRSF PIRSF003169 1 383 6.7E-163 T 06-07-2017 IPR016381 Signal transduction histidine kinase, DegS GO:0000155|GO:0000160|GO:0004673 GTHT12_RS16295 805f855315765e60dc8e997d565dfb9a 383 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 292 379 3.0E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS16295 805f855315765e60dc8e997d565dfb9a 383 SMART SM00387 288 381 7.6E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS16295 805f855315765e60dc8e997d565dfb9a 383 SUPERFAMILY SSF55874 267 378 5.27E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS16295 805f855315765e60dc8e997d565dfb9a 383 Pfam PF05384 Sensor protein DegS 13 171 7.6E-57 T 06-07-2017 IPR008595 Sensor DegS GO:0007165|GO:0016301 GTHT12_RS16295 805f855315765e60dc8e997d565dfb9a 383 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 338 6.8E-5 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS16295 805f855315765e60dc8e997d565dfb9a 383 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 378 6.8E-5 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS16295 805f855315765e60dc8e997d565dfb9a 383 PRINTS PR00344 Bacterial sensor protein C-terminal signature 341 359 6.8E-5 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS16295 805f855315765e60dc8e997d565dfb9a 383 Gene3D G3DSA:3.30.565.10 290 381 1.4E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS13080 a831a9dfa57554ee1e047522949aa341 148 Pfam PF09424 Yqey-like protein 5 147 2.5E-56 T 06-07-2017 IPR019004 Uncharacterised domain YOR215C, mitochondrial GTHT12_RS13080 a831a9dfa57554ee1e047522949aa341 148 Gene3D G3DSA:1.10.10.410 92 148 4.0E-26 T 06-07-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal GTHT12_RS13080 a831a9dfa57554ee1e047522949aa341 148 Gene3D G3DSA:1.10.1510.10 2 91 1.1E-30 T 06-07-2017 GTHT12_RS13080 a831a9dfa57554ee1e047522949aa341 148 SUPERFAMILY SSF89095 2 147 5.23E-45 T 06-07-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 GTHT12_RS11100 47824a2349b9c70e4a01b506a287e68a 815 SUPERFAMILY SSF56024 24 145 7.85E-8 T 06-07-2017 GTHT12_RS11100 47824a2349b9c70e4a01b506a287e68a 815 SUPERFAMILY SSF52540 269 558 1.48E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11100 47824a2349b9c70e4a01b506a287e68a 815 Gene3D G3DSA:3.40.50.300 440 563 1.5E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11100 47824a2349b9c70e4a01b506a287e68a 815 Pfam PF13091 PLD-like domain 17 145 6.6E-10 T 06-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 GTHT12_RS11100 47824a2349b9c70e4a01b506a287e68a 815 Gene3D G3DSA:3.30.870.10 24 149 1.0E-5 T 06-07-2017 GTHT12_RS11100 47824a2349b9c70e4a01b506a287e68a 815 Gene3D G3DSA:3.40.50.300 216 373 6.8E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11100 47824a2349b9c70e4a01b506a287e68a 815 Pfam PF04851 Type III restriction enzyme, res subunit 223 369 4.0E-29 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 GTHT12_RS11100 47824a2349b9c70e4a01b506a287e68a 815 Pfam PF00271 Helicase conserved C-terminal domain 445 543 1.8E-12 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS11100 47824a2349b9c70e4a01b506a287e68a 815 SMART SM00490 463 544 2.0E-9 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS11100 47824a2349b9c70e4a01b506a287e68a 815 SMART SM00487 220 390 1.2E-10 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain GTHT12_RS04105 2ba9f774d3ff9bf0f9499057116568d9 352 SUPERFAMILY SSF49503 61 206 3.41E-36 T 06-07-2017 IPR008972 Cupredoxin GTHT12_RS04105 2ba9f774d3ff9bf0f9499057116568d9 352 PRINTS PR00695 Copper containing nitrite reductase signature 151 166 9.2E-16 T 06-07-2017 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 GTHT12_RS04105 2ba9f774d3ff9bf0f9499057116568d9 352 PRINTS PR00695 Copper containing nitrite reductase signature 168 184 9.2E-16 T 06-07-2017 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 GTHT12_RS04105 2ba9f774d3ff9bf0f9499057116568d9 352 PRINTS PR00695 Copper containing nitrite reductase signature 67 85 9.2E-16 T 06-07-2017 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 GTHT12_RS04105 2ba9f774d3ff9bf0f9499057116568d9 352 PRINTS PR00695 Copper containing nitrite reductase signature 93 109 9.2E-16 T 06-07-2017 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 GTHT12_RS04105 2ba9f774d3ff9bf0f9499057116568d9 352 Gene3D G3DSA:2.60.40.420 48 182 2.0E-31 T 06-07-2017 IPR008972 Cupredoxin GTHT12_RS04105 2ba9f774d3ff9bf0f9499057116568d9 352 Pfam PF07731 Multicopper oxidase 230 339 9.6E-7 T 06-07-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 GTHT12_RS04105 2ba9f774d3ff9bf0f9499057116568d9 352 SUPERFAMILY SSF49503 194 345 3.62E-36 T 06-07-2017 IPR008972 Cupredoxin GTHT12_RS04105 2ba9f774d3ff9bf0f9499057116568d9 352 Gene3D G3DSA:2.60.40.420 183 328 2.0E-36 T 06-07-2017 IPR008972 Cupredoxin GTHT12_RS04105 2ba9f774d3ff9bf0f9499057116568d9 352 Pfam PF07732 Multicopper oxidase 79 187 2.1E-11 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 GTHT12_RS11145 1334fa7fde2d5d461724b80353f61fc6 430 ProSitePatterns PS00217 Sugar transport proteins signature 2. 128 153 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 GTHT12_RS11145 1334fa7fde2d5d461724b80353f61fc6 430 Pfam PF07690 Major Facilitator Superfamily 63 374 4.9E-28 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS11145 1334fa7fde2d5d461724b80353f61fc6 430 Gene3D G3DSA:1.20.1250.20 241 421 1.4E-23 T 06-07-2017 GTHT12_RS11145 1334fa7fde2d5d461724b80353f61fc6 430 SUPERFAMILY SSF103473 12 422 6.54E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS11145 1334fa7fde2d5d461724b80353f61fc6 430 Gene3D G3DSA:1.20.1250.20 33 225 2.0E-20 T 06-07-2017 GTHT12_RS03645 bb41b6112584c77a06d2e7c71f5ef02f 113 SUPERFAMILY SSF109915 2 112 1.57E-48 T 06-07-2017 IPR015058 Protein of unknown function DUF1878 GTHT12_RS03645 bb41b6112584c77a06d2e7c71f5ef02f 113 Gene3D G3DSA:1.10.3750.10 1 112 6.4E-46 T 06-07-2017 IPR015058 Protein of unknown function DUF1878 GTHT12_RS03645 bb41b6112584c77a06d2e7c71f5ef02f 113 Pfam PF08963 Protein of unknown function (DUF1878) 1 110 2.8E-46 T 06-07-2017 IPR015058 Protein of unknown function DUF1878 GTHT12_RS03645 bb41b6112584c77a06d2e7c71f5ef02f 113 ProDom PD073069 YHAI 3D-STRUCTURE 10 101 4.0E-46 T 06-07-2017 IPR015058 Protein of unknown function DUF1878 GTHT12_RS04050 86fe9d95e2538041d344676eb1bddeca 69 Gene3D G3DSA:3.30.110.40 2 69 2.6E-11 T 06-07-2017 IPR001455 TusA-like domain GTHT12_RS04050 86fe9d95e2538041d344676eb1bddeca 69 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 3 68 1.5E-21 T 06-07-2017 IPR018720 Domain of unknown function DUF2249 GTHT12_RS04050 86fe9d95e2538041d344676eb1bddeca 69 SUPERFAMILY SSF64307 1 69 9.68E-16 T 06-07-2017 IPR001455 TusA-like domain GTHT12_RS05660 ef96e74b60d9c599cfa93023c0bdc3fc 443 Gene3D G3DSA:3.40.50.1010 6 147 8.2E-11 T 06-07-2017 IPR029060 PIN domain-like GTHT12_RS05660 ef96e74b60d9c599cfa93023c0bdc3fc 443 Pfam PF13638 PIN domain 6 148 4.9E-33 T 06-07-2017 IPR002716 PIN domain GTHT12_RS05660 ef96e74b60d9c599cfa93023c0bdc3fc 443 SMART SM00670 4 136 1.6E-26 T 06-07-2017 IPR002716 PIN domain GTHT12_RS05660 ef96e74b60d9c599cfa93023c0bdc3fc 443 Pfam PF02562 PhoH-like protein 234 437 7.6E-56 T 06-07-2017 IPR003714 PhoH-like protein GO:0005524 GTHT12_RS05660 ef96e74b60d9c599cfa93023c0bdc3fc 443 Gene3D G3DSA:3.40.50.300 232 442 7.9E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05660 ef96e74b60d9c599cfa93023c0bdc3fc 443 SUPERFAMILY SSF52540 23 123 1.43E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05660 ef96e74b60d9c599cfa93023c0bdc3fc 443 SUPERFAMILY SSF52540 233 423 1.43E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07745 32bf2e02ac3e6ca7665509b6e6400764 326 Pfam PF02126 Phosphotriesterase family 13 324 1.1E-60 T 06-07-2017 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 GTHT12_RS07745 32bf2e02ac3e6ca7665509b6e6400764 326 SUPERFAMILY SSF51556 3 325 8.43E-85 T 06-07-2017 IPR032466 Metal-dependent hydrolase GTHT12_RS07745 32bf2e02ac3e6ca7665509b6e6400764 326 PIRSF PIRSF016839 2 326 7.3E-66 T 06-07-2017 GTHT12_RS07745 32bf2e02ac3e6ca7665509b6e6400764 326 Gene3D G3DSA:3.20.20.140 4 325 3.9E-107 T 06-07-2017 GTHT12_RS02530 98ac4dcaec3413811cbe7c8d530ac5f7 469 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 397 428 - T 06-07-2017 IPR030390 RNA methyltransferase TrmA, active site GTHT12_RS02530 98ac4dcaec3413811cbe7c8d530ac5f7 469 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 29 458 9.6E-177 T 06-07-2017 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 GTHT12_RS02530 98ac4dcaec3413811cbe7c8d530ac5f7 469 SUPERFAMILY SSF50249 8 70 3.77E-16 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS02530 98ac4dcaec3413811cbe7c8d530ac5f7 469 Gene3D G3DSA:3.40.50.150 263 463 3.6E-62 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS02530 98ac4dcaec3413811cbe7c8d530ac5f7 469 Pfam PF01938 TRAM domain 16 70 7.6E-10 T 06-07-2017 IPR002792 TRAM domain GTHT12_RS02530 98ac4dcaec3413811cbe7c8d530ac5f7 469 Gene3D G3DSA:2.40.50.140 8 91 1.4E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS02530 98ac4dcaec3413811cbe7c8d530ac5f7 469 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 277 460 4.1E-15 T 06-07-2017 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 GTHT12_RS02530 98ac4dcaec3413811cbe7c8d530ac5f7 469 SUPERFAMILY SSF53335 80 463 2.2E-81 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS02530 98ac4dcaec3413811cbe7c8d530ac5f7 469 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 448 458 - T 06-07-2017 IPR030391 RNA methyltransferase TrmA, conserved site GTHT12_RS07975 a2af918bc989bde2f2b8496f72eac61b 194 Pfam PF00156 Phosphoribosyl transferase domain 33 156 2.1E-11 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 GTHT12_RS07975 a2af918bc989bde2f2b8496f72eac61b 194 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 1 188 6.4E-76 T 06-07-2017 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 GTHT12_RS07975 a2af918bc989bde2f2b8496f72eac61b 194 Gene3D G3DSA:3.40.50.2020 1 191 1.5E-60 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS07975 a2af918bc989bde2f2b8496f72eac61b 194 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 40.622 T 06-07-2017 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 GTHT12_RS07975 a2af918bc989bde2f2b8496f72eac61b 194 SUPERFAMILY SSF53271 1 188 3.27E-44 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS11885 133e518d211f7f36b7b32105dea84b4c 507 Gene3D G3DSA:3.40.50.300 3 191 1.9E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11885 133e518d211f7f36b7b32105dea84b4c 507 SMART SM00490 242 324 8.6E-21 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS11885 133e518d211f7f36b7b32105dea84b4c 507 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 6 345 2.5E-106 T 06-07-2017 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 GTHT12_RS11885 133e518d211f7f36b7b32105dea84b4c 507 Pfam PF16124 RecQ zinc-binding 418 466 1.5E-7 T 06-07-2017 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain GTHT12_RS11885 133e518d211f7f36b7b32105dea84b4c 507 Gene3D G3DSA:3.40.50.300 197 338 3.3E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11885 133e518d211f7f36b7b32105dea84b4c 507 SUPERFAMILY SSF52540 57 340 9.28E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11885 133e518d211f7f36b7b32105dea84b4c 507 Pfam PF00271 Helicase conserved C-terminal domain 226 324 1.8E-14 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS11885 133e518d211f7f36b7b32105dea84b4c 507 SMART SM00487 13 208 1.1E-31 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain GTHT12_RS11885 133e518d211f7f36b7b32105dea84b4c 507 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 131 140 - T 06-07-2017 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site GO:0003676|GO:0005524|GO:0008026 GTHT12_RS11885 133e518d211f7f36b7b32105dea84b4c 507 Gene3D G3DSA:1.10.10.10 419 466 1.5E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS11885 133e518d211f7f36b7b32105dea84b4c 507 Pfam PF00270 DEAD/DEAH box helicase 19 178 3.1E-20 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 GTHT12_RS14270 7b2c32e30be87807d866720261c04b6b 200 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 24 38 9.2E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS14270 7b2c32e30be87807d866720261c04b6b 200 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 54 9.2E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS14270 7b2c32e30be87807d866720261c04b6b 200 SUPERFAMILY SSF46785 2 68 7.01E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS14270 7b2c32e30be87807d866720261c04b6b 200 SMART SM00345 5 64 1.9E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS14270 7b2c32e30be87807d866720261c04b6b 200 SMART SM00895 89 194 1.2E-4 T 06-07-2017 IPR011711 GntR, C-terminal GTHT12_RS14270 7b2c32e30be87807d866720261c04b6b 200 Gene3D G3DSA:1.20.120.530 130 191 5.7E-4 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal GTHT12_RS14270 7b2c32e30be87807d866720261c04b6b 200 Gene3D G3DSA:1.10.10.10 2 75 1.4E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS14270 7b2c32e30be87807d866720261c04b6b 200 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 63 3.3E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS14270 7b2c32e30be87807d866720261c04b6b 200 SUPERFAMILY SSF48008 88 191 9.94E-7 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal GTHT12_RS12405 70905a00514e318aeee615f10d70f9e8 468 Pfam PF00512 His Kinase A (phospho-acceptor) domain 241 306 1.7E-20 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS12405 70905a00514e318aeee615f10d70f9e8 468 SUPERFAMILY SSF47384 223 306 1.26E-22 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS12405 70905a00514e318aeee615f10d70f9e8 468 Pfam PF00672 HAMP domain 173 234 7.2E-15 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS12405 70905a00514e318aeee615f10d70f9e8 468 SMART SM00304 187 239 1.3E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS12405 70905a00514e318aeee615f10d70f9e8 468 Gene3D G3DSA:3.30.565.10 293 467 5.2E-51 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS12405 70905a00514e318aeee615f10d70f9e8 468 Gene3D G3DSA:1.10.287.130 230 292 1.7E-22 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS12405 70905a00514e318aeee615f10d70f9e8 468 SUPERFAMILY SSF55874 297 465 4.58E-49 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS12405 70905a00514e318aeee615f10d70f9e8 468 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 352 463 7.5E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS12405 70905a00514e318aeee615f10d70f9e8 468 SUPERFAMILY SSF158472 187 234 3.79E-11 T 06-07-2017 GTHT12_RS12405 70905a00514e318aeee615f10d70f9e8 468 SMART SM00388 240 307 1.5E-20 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS12405 70905a00514e318aeee615f10d70f9e8 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 404 6.1E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS12405 70905a00514e318aeee615f10d70f9e8 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 443 6.1E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS12405 70905a00514e318aeee615f10d70f9e8 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 462 6.1E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS12405 70905a00514e318aeee615f10d70f9e8 468 SMART SM00387 352 465 4.8E-44 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS09885 b54d71df914d97387d3b4846c03442a8 547 Gene3D G3DSA:3.40.190.10 189 385 3.8E-70 T 06-07-2017 GTHT12_RS09885 b54d71df914d97387d3b4846c03442a8 547 Gene3D G3DSA:3.40.190.10 492 542 3.8E-70 T 06-07-2017 GTHT12_RS09885 b54d71df914d97387d3b4846c03442a8 547 Gene3D G3DSA:3.40.190.10 71 188 4.7E-13 T 06-07-2017 GTHT12_RS09885 b54d71df914d97387d3b4846c03442a8 547 SUPERFAMILY SSF53850 22 543 4.67E-89 T 06-07-2017 GTHT12_RS09885 b54d71df914d97387d3b4846c03442a8 547 Pfam PF01547 Bacterial extracellular solute-binding protein 66 366 5.0E-17 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 GTHT12_RS14265 3e3b03e084666ee4220cd752330d25dc 290 Pfam PF01039 Carboxyl transferase domain 62 242 3.1E-20 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GTHT12_RS14265 3e3b03e084666ee4220cd752330d25dc 290 Gene3D G3DSA:3.90.226.10 22 280 1.2E-76 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS14265 3e3b03e084666ee4220cd752330d25dc 290 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 6 280 4.5E-129 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 GTHT12_RS14265 3e3b03e084666ee4220cd752330d25dc 290 SUPERFAMILY SSF52096 29 282 7.46E-84 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS14265 3e3b03e084666ee4220cd752330d25dc 290 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 3 281 39.458 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 GTHT12_RS14265 3e3b03e084666ee4220cd752330d25dc 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 200 217 3.8E-38 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 GTHT12_RS14265 3e3b03e084666ee4220cd752330d25dc 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 163 181 3.8E-38 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 GTHT12_RS14265 3e3b03e084666ee4220cd752330d25dc 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 229 240 3.8E-38 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 GTHT12_RS14265 3e3b03e084666ee4220cd752330d25dc 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 251 260 3.8E-38 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 GTHT12_RS14265 3e3b03e084666ee4220cd752330d25dc 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 129 143 3.8E-38 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 GTHT12_RS04535 7131071383c9baa81df2cccc8795a015 286 Gene3D G3DSA:3.30.240.20 169 229 1.1E-19 T 06-07-2017 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain GTHT12_RS04535 7131071383c9baa81df2cccc8795a015 286 Gene3D G3DSA:3.30.240.20 79 154 5.5E-31 T 06-07-2017 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain GTHT12_RS04535 7131071383c9baa81df2cccc8795a015 286 Pfam PF07870 Protein of unknown function (DUF1657) 236 284 4.4E-15 T 06-07-2017 IPR012452 Protein of unknown function DUF1657 GTHT12_RS04535 7131071383c9baa81df2cccc8795a015 286 Pfam PF04239 Protein of unknown function (DUF421) 89 204 1.7E-34 T 06-07-2017 IPR007353 Protein of unknown function DUF421 GTHT12_RS07310 f073cf1c083b62b6d799f4d6dbeb4c15 308 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 23 297 5.8E-87 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 GTHT12_RS07310 f073cf1c083b62b6d799f4d6dbeb4c15 308 SUPERFAMILY SSF160240 229 297 3.27E-8 T 06-07-2017 GTHT12_RS07310 f073cf1c083b62b6d799f4d6dbeb4c15 308 Pfam PF01545 Cation efflux family 28 220 1.1E-49 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 GTHT12_RS07310 f073cf1c083b62b6d799f4d6dbeb4c15 308 SUPERFAMILY SSF161111 22 221 1.18E-58 T 06-07-2017 GTHT12_RS07310 f073cf1c083b62b6d799f4d6dbeb4c15 308 Gene3D G3DSA:1.20.1510.10 24 220 4.5E-61 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain GTHT12_RS03625 16092cd6c12597f5ed023c50137cac3e 362 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 6 360 4.7E-158 T 06-07-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 GTHT12_RS03625 16092cd6c12597f5ed023c50137cac3e 362 Gene3D G3DSA:3.40.640.10 19 258 1.3E-103 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS03625 16092cd6c12597f5ed023c50137cac3e 362 SUPERFAMILY SSF53383 4 360 7.4E-122 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS03625 16092cd6c12597f5ed023c50137cac3e 362 PIRSF PIRSF000525 1 362 5.6E-155 T 06-07-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 GTHT12_RS03625 16092cd6c12597f5ed023c50137cac3e 362 Gene3D G3DSA:3.90.1150.10 259 359 6.3E-41 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS03625 16092cd6c12597f5ed023c50137cac3e 362 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 4 361 50.106 T 06-07-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 GTHT12_RS03625 16092cd6c12597f5ed023c50137cac3e 362 Pfam PF00266 Aminotransferase class-V 6 349 2.1E-52 T 06-07-2017 IPR000192 Aminotransferase class V domain GTHT12_RS14365 8dfcefaadf24a716e07fa8c320a1236b 396 Gene3D G3DSA:3.30.420.40 87 203 5.4E-11 T 06-07-2017 GTHT12_RS14365 8dfcefaadf24a716e07fa8c320a1236b 396 Gene3D G3DSA:3.30.420.40 204 393 6.5E-80 T 06-07-2017 GTHT12_RS14365 8dfcefaadf24a716e07fa8c320a1236b 396 Hamap MF_00020 Acetate kinase [ackA]. 1 396 201.702 T 06-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 GTHT12_RS14365 8dfcefaadf24a716e07fa8c320a1236b 396 Pfam PF00871 Acetokinase family 3 388 1.3E-173 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 GTHT12_RS14365 8dfcefaadf24a716e07fa8c320a1236b 396 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 202 219 - T 06-07-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 GTHT12_RS14365 8dfcefaadf24a716e07fa8c320a1236b 396 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 06-07-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 GTHT12_RS14365 8dfcefaadf24a716e07fa8c320a1236b 396 PIRSF PIRSF000722 1 396 2.0E-154 T 06-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 GTHT12_RS14365 8dfcefaadf24a716e07fa8c320a1236b 396 PRINTS PR00471 Acetate kinase family signature 299 312 4.5E-48 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 GTHT12_RS14365 8dfcefaadf24a716e07fa8c320a1236b 396 PRINTS PR00471 Acetate kinase family signature 321 337 4.5E-48 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 GTHT12_RS14365 8dfcefaadf24a716e07fa8c320a1236b 396 PRINTS PR00471 Acetate kinase family signature 4 15 4.5E-48 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 GTHT12_RS14365 8dfcefaadf24a716e07fa8c320a1236b 396 PRINTS PR00471 Acetate kinase family signature 375 387 4.5E-48 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 GTHT12_RS14365 8dfcefaadf24a716e07fa8c320a1236b 396 PRINTS PR00471 Acetate kinase family signature 172 185 4.5E-48 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 GTHT12_RS14365 8dfcefaadf24a716e07fa8c320a1236b 396 PRINTS PR00471 Acetate kinase family signature 202 223 4.5E-48 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 GTHT12_RS14365 8dfcefaadf24a716e07fa8c320a1236b 396 SUPERFAMILY SSF53067 1 194 2.72E-73 T 06-07-2017 GTHT12_RS14365 8dfcefaadf24a716e07fa8c320a1236b 396 SUPERFAMILY SSF53067 157 393 3.89E-95 T 06-07-2017 GTHT12_RS14365 8dfcefaadf24a716e07fa8c320a1236b 396 TIGRFAM TIGR00016 ackA: acetate kinase 2 394 2.6E-179 T 06-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 GTHT12_RS14395 0ea283dc6ac21f57ad969077ec2952e3 335 Gene3D G3DSA:3.90.226.10 39 172 6.6E-59 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS14395 0ea283dc6ac21f57ad969077ec2952e3 335 Gene3D G3DSA:3.90.226.10 210 286 6.6E-59 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS14395 0ea283dc6ac21f57ad969077ec2952e3 335 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 61 281 1.0E-80 T 06-07-2017 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 GTHT12_RS14395 0ea283dc6ac21f57ad969077ec2952e3 335 SUPERFAMILY SSF52096 211 272 1.19E-42 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS14395 0ea283dc6ac21f57ad969077ec2952e3 335 SUPERFAMILY SSF52096 58 180 1.19E-42 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS14395 0ea283dc6ac21f57ad969077ec2952e3 335 Pfam PF01343 Peptidase family S49 133 282 1.4E-54 T 06-07-2017 IPR002142 Peptidase S49 GO:0006508|GO:0008233 GTHT12_RS14690 d95565eabe65a985ec22417ed3edfc9c 192 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 4 183 23.383 T 06-07-2017 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 GTHT12_RS14690 d95565eabe65a985ec22417ed3edfc9c 192 Gene3D G3DSA:3.90.1140.10 5 185 1.5E-49 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase GTHT12_RS14690 d95565eabe65a985ec22417ed3edfc9c 192 SUPERFAMILY SSF55144 5 183 1.03E-43 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase GTHT12_RS14690 d95565eabe65a985ec22417ed3edfc9c 192 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 5 183 5.4E-48 T 06-07-2017 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 GTHT12_RS14690 d95565eabe65a985ec22417ed3edfc9c 192 Pfam PF02834 LigT like Phosphoesterase 100 175 1.6E-10 T 06-07-2017 IPR014051 Phosphoesterase, HXTX GTHT12_RS14690 d95565eabe65a985ec22417ed3edfc9c 192 Pfam PF02834 LigT like Phosphoesterase 10 94 6.5E-17 T 06-07-2017 IPR014051 Phosphoesterase, HXTX GTHT12_RS08000 59ca6de122d53be7601cc26f8d3bc6cb 172 SUPERFAMILY SSF46785 6 167 1.52E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS08000 59ca6de122d53be7601cc26f8d3bc6cb 172 Gene3D G3DSA:1.10.10.10 6 84 7.9E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS08000 59ca6de122d53be7601cc26f8d3bc6cb 172 Pfam PF03551 Transcriptional regulator PadR-like family 8 80 8.0E-15 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal GTHT12_RS09735 61d2c3e94ed7649e10ba1086d8142e6f 191 ProDom PD102989 YKOP PLASMID 10 185 9.0E-75 T 06-07-2017 GTHT12_RS14885 7c4df17cb2a90215cf3bba26722bf447 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 267 2.9E-92 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 GTHT12_RS14885 7c4df17cb2a90215cf3bba26722bf447 272 TIGRFAM TIGR01929 menB: naphthoate synthase 11 268 2.0E-133 T 06-07-2017 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 GTHT12_RS14885 7c4df17cb2a90215cf3bba26722bf447 272 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 5 271 56.567 T 06-07-2017 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 GTHT12_RS14885 7c4df17cb2a90215cf3bba26722bf447 272 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 110 130 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 GTHT12_RS14885 7c4df17cb2a90215cf3bba26722bf447 272 Gene3D G3DSA:3.90.226.10 11 209 3.9E-72 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS14885 7c4df17cb2a90215cf3bba26722bf447 272 SUPERFAMILY SSF52096 5 267 3.13E-82 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS14885 7c4df17cb2a90215cf3bba26722bf447 272 Gene3D G3DSA:1.10.12.10 210 260 1.6E-28 T 06-07-2017 IPR014748 Crontonase, C-terminal GTHT12_RS13945 987c9dffd4d69891af629abca2ebfb19 585 Gene3D G3DSA:1.20.58.100 425 540 4.9E-32 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GTHT12_RS13945 987c9dffd4d69891af629abca2ebfb19 585 Gene3D G3DSA:3.50.50.60 349 415 1.0E-88 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS13945 987c9dffd4d69891af629abca2ebfb19 585 Gene3D G3DSA:3.50.50.60 6 236 1.0E-88 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS13945 987c9dffd4d69891af629abca2ebfb19 585 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 396 411 3.2E-5 T 06-07-2017 GTHT12_RS13945 987c9dffd4d69891af629abca2ebfb19 585 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 3.2E-5 T 06-07-2017 GTHT12_RS13945 987c9dffd4d69891af629abca2ebfb19 585 Pfam PF02910 Fumarate reductase flavoprotein C-term 452 577 1.6E-40 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GTHT12_RS13945 987c9dffd4d69891af629abca2ebfb19 585 Gene3D G3DSA:3.90.700.10 237 347 4.4E-25 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 GTHT12_RS13945 987c9dffd4d69891af629abca2ebfb19 585 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 39 48 - T 06-07-2017 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GTHT12_RS13945 987c9dffd4d69891af629abca2ebfb19 585 SUPERFAMILY SSF51905 357 426 1.45E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS13945 987c9dffd4d69891af629abca2ebfb19 585 SUPERFAMILY SSF51905 6 247 1.45E-64 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS13945 987c9dffd4d69891af629abca2ebfb19 585 SUPERFAMILY SSF56425 231 353 3.89E-32 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 GTHT12_RS13945 987c9dffd4d69891af629abca2ebfb19 585 Pfam PF00890 FAD binding domain 6 392 3.1E-90 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 GTHT12_RS13945 987c9dffd4d69891af629abca2ebfb19 585 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.1E-7 T 06-07-2017 GTHT12_RS13945 987c9dffd4d69891af629abca2ebfb19 585 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 378 1.1E-7 T 06-07-2017 GTHT12_RS13945 987c9dffd4d69891af629abca2ebfb19 585 Gene3D G3DSA:4.10.80.40 541 567 4.9E-4 T 06-07-2017 GTHT12_RS13945 987c9dffd4d69891af629abca2ebfb19 585 SUPERFAMILY SSF46977 443 577 4.32E-46 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 GTHT12_RS13945 987c9dffd4d69891af629abca2ebfb19 585 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 6 577 3.0E-278 T 06-07-2017 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 GTHT12_RS14815 f157808b5cbf5f5418284d90363e5975 155 SUPERFAMILY SSF55811 23 99 5.69E-21 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 GTHT12_RS14815 f157808b5cbf5f5418284d90363e5975 155 Gene3D G3DSA:3.90.79.10 28 91 2.1E-18 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 GTHT12_RS14815 f157808b5cbf5f5418284d90363e5975 155 PRINTS PR00502 NUDIX hydrolase family signature 48 62 3.0E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 GTHT12_RS14815 f157808b5cbf5f5418284d90363e5975 155 PRINTS PR00502 NUDIX hydrolase family signature 62 77 3.0E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 GTHT12_RS14815 f157808b5cbf5f5418284d90363e5975 155 TIGRFAM TIGR02705 nudix_YtkD: nucleoside triphosphatase YtkD 3 153 1.8E-68 T 06-07-2017 IPR014078 Nucleoside triphosphatase YtkD MetaCyc: PWY-6502 GTHT12_RS14815 f157808b5cbf5f5418284d90363e5975 155 Pfam PF00293 NUDIX domain 30 85 5.5E-13 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 GTHT12_RS14815 f157808b5cbf5f5418284d90363e5975 155 ProSitePatterns PS00893 Nudix box signature. 53 74 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 GTHT12_RS16625 fe91c30818cbbe524bd73f187cf1dfc5 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 3.0E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS16625 fe91c30818cbbe524bd73f187cf1dfc5 211 Gene3D G3DSA:1.10.357.10 74 210 2.1E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 GTHT12_RS16625 fe91c30818cbbe524bd73f187cf1dfc5 211 SUPERFAMILY SSF46689 14 84 3.13E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS16625 fe91c30818cbbe524bd73f187cf1dfc5 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 1.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS16625 fe91c30818cbbe524bd73f187cf1dfc5 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 1.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS16625 fe91c30818cbbe524bd73f187cf1dfc5 211 Gene3D G3DSA:1.10.10.60 15 73 8.6E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS16625 fe91c30818cbbe524bd73f187cf1dfc5 211 ProSitePatterns PS01081 TetR-type HTH domain signature. 39 70 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site GTHT12_RS16625 fe91c30818cbbe524bd73f187cf1dfc5 211 SUPERFAMILY SSF48498 95 210 2.31E-18 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal GTHT12_RS00380 48263af187150f734849244b7a7a9b06 631 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 110 601 7.9E-249 T 06-07-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 GTHT12_RS00380 48263af187150f734849244b7a7a9b06 631 SUPERFAMILY SSF52540 152 402 3.86E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00380 48263af187150f734849244b7a7a9b06 631 Gene3D G3DSA:1.10.8.60 341 405 4.9E-28 T 06-07-2017 GTHT12_RS00380 48263af187150f734849244b7a7a9b06 631 ProSitePatterns PS00674 AAA-protein family signature. 301 319 - T 06-07-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 GTHT12_RS00380 48263af187150f734849244b7a7a9b06 631 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 198 330 1.3E-46 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 GTHT12_RS00380 48263af187150f734849244b7a7a9b06 631 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 610 39.1 T 06-07-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 GTHT12_RS00380 48263af187150f734849244b7a7a9b06 631 Pfam PF01434 Peptidase family M41 392 600 5.2E-88 T 06-07-2017 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 GTHT12_RS00380 48263af187150f734849244b7a7a9b06 631 Gene3D G3DSA:3.40.50.300 154 340 8.0E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00380 48263af187150f734849244b7a7a9b06 631 Pfam PF06480 FtsH Extracellular 9 103 1.1E-8 T 06-07-2017 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 GTHT12_RS00380 48263af187150f734849244b7a7a9b06 631 SMART SM00382 194 333 5.6E-26 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS00380 48263af187150f734849244b7a7a9b06 631 SUPERFAMILY SSF140990 412 608 3.27E-76 T 06-07-2017 GTHT12_RS01630 51e6095ef75d299b55246f4460c5a57a 346 Gene3D G3DSA:3.90.650.10 169 339 4.9E-71 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain GTHT12_RS01630 51e6095ef75d299b55246f4460c5a57a 346 SUPERFAMILY SSF55326 4 166 4.93E-52 T 06-07-2017 GTHT12_RS01630 51e6095ef75d299b55246f4460c5a57a 346 Pfam PF02769 AIR synthase related protein, C-terminal domain 173 340 4.7E-37 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain GTHT12_RS01630 51e6095ef75d299b55246f4460c5a57a 346 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 4 334 3.6E-138 T 06-07-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 GTHT12_RS01630 51e6095ef75d299b55246f4460c5a57a 346 Pfam PF00586 AIR synthase related protein, N-terminal domain 71 160 7.9E-17 T 06-07-2017 IPR016188 PurM-like, N-terminal domain GTHT12_RS01630 51e6095ef75d299b55246f4460c5a57a 346 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 3 341 47.936 T 06-07-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 GTHT12_RS01630 51e6095ef75d299b55246f4460c5a57a 346 SUPERFAMILY SSF56042 169 339 8.07E-60 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain GTHT12_RS01630 51e6095ef75d299b55246f4460c5a57a 346 Gene3D G3DSA:3.30.1330.10 19 166 3.3E-64 T 06-07-2017 IPR016188 PurM-like, N-terminal domain GTHT12_RS00560 1117f1ecd62126b729bf9ac70979c3e1 140 Gene3D G3DSA:1.10.1520.10 9 135 7.8E-52 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 GTHT12_RS00560 1117f1ecd62126b729bf9ac70979c3e1 140 SMART SM00535 1 137 1.4E-6 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 GTHT12_RS00560 1117f1ecd62126b729bf9ac70979c3e1 140 PIRSF PIRSF005520 1 138 4.9E-53 T 06-07-2017 IPR008226 Mini-ribonuclease 3 family GTHT12_RS00560 1117f1ecd62126b729bf9ac70979c3e1 140 SUPERFAMILY SSF69065 9 131 2.09E-43 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 GTHT12_RS00560 1117f1ecd62126b729bf9ac70979c3e1 140 Pfam PF00636 Ribonuclease III domain 17 116 1.1E-16 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 GTHT12_RS00560 1117f1ecd62126b729bf9ac70979c3e1 140 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 7 133 31.125 T 06-07-2017 IPR008226 Mini-ribonuclease 3 family GTHT12_RS06415 b8235bd086f17dce31b9d71746fd0a9e 257 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 17 38 6.2E-25 T 06-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 GTHT12_RS06415 b8235bd086f17dce31b9d71746fd0a9e 257 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 198 217 6.2E-25 T 06-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 GTHT12_RS06415 b8235bd086f17dce31b9d71746fd0a9e 257 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 74 93 6.2E-25 T 06-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 GTHT12_RS06415 b8235bd086f17dce31b9d71746fd0a9e 257 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 176 198 6.2E-25 T 06-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 GTHT12_RS06415 b8235bd086f17dce31b9d71746fd0a9e 257 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 10 251 5.8E-64 T 06-07-2017 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 GTHT12_RS06415 b8235bd086f17dce31b9d71746fd0a9e 257 Pfam PF01311 Bacterial export proteins, family 1 9 241 1.2E-69 T 06-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 GTHT12_RS13085 3558ae41bc9200a6ada092824ca0a2a4 57 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 22.548 T 06-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS13085 3558ae41bc9200a6ada092824ca0a2a4 57 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 7.8E-16 T 06-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS13085 3558ae41bc9200a6ada092824ca0a2a4 57 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 7.8E-16 T 06-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS13085 3558ae41bc9200a6ada092824ca0a2a4 57 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 7.8E-16 T 06-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS13085 3558ae41bc9200a6ada092824ca0a2a4 57 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 7.8E-16 T 06-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS13085 3558ae41bc9200a6ada092824ca0a2a4 57 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 56 3.6E-22 T 06-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS13085 3558ae41bc9200a6ada092824ca0a2a4 57 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 06-07-2017 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS13085 3558ae41bc9200a6ada092824ca0a2a4 57 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 5.0E-9 T 06-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS13085 3558ae41bc9200a6ada092824ca0a2a4 57 Pfam PF01165 Ribosomal protein S21 6 56 2.8E-21 T 06-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00615 77f40fef01f93f98f46ab98c47f5f048 200 Pfam PF05175 Methyltransferase small domain 28 196 2.2E-51 T 06-07-2017 IPR007848 Methyltransferase small domain GO:0008168 GTHT12_RS00615 77f40fef01f93f98f46ab98c47f5f048 200 Gene3D G3DSA:3.40.50.150 13 196 2.2E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS00615 77f40fef01f93f98f46ab98c47f5f048 200 SUPERFAMILY SSF53335 11 199 1.5E-39 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS02650 f8b4ee116fc7415fc3b0ea8e996c105e 160 TIGRFAM TIGR03927 T7SS_EssA_Firm: type VII secretion protein EssA 9 157 7.4E-39 T 06-07-2017 IPR018920 WXG100 secretion system EssA GTHT12_RS02650 f8b4ee116fc7415fc3b0ea8e996c105e 160 ProDom PD090911 YUEC MEMBRANE TRANSMEMBRANE 22 133 4.0E-7 T 06-07-2017 IPR020212 Uncharacterised protein family, YueC, transmembrane GTHT12_RS06115 17c0c7c20c06e907772858da64d832b8 665 SUPERFAMILY SSF54184 510 571 4.45E-5 T 06-07-2017 GTHT12_RS06115 17c0c7c20c06e907772858da64d832b8 665 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 GTHT12_RS06115 17c0c7c20c06e907772858da64d832b8 665 SMART SM00220 11 271 7.4E-73 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 GTHT12_RS06115 17c0c7c20c06e907772858da64d832b8 665 SMART SM00740 438 505 3.6E-10 T 06-07-2017 IPR005543 PASTA domain GTHT12_RS06115 17c0c7c20c06e907772858da64d832b8 665 SMART SM00740 506 572 1.9E-18 T 06-07-2017 IPR005543 PASTA domain GTHT12_RS06115 17c0c7c20c06e907772858da64d832b8 665 SMART SM00740 370 437 2.0E-12 T 06-07-2017 IPR005543 PASTA domain GTHT12_RS06115 17c0c7c20c06e907772858da64d832b8 665 Pfam PF03793 PASTA domain 374 434 9.4E-13 T 06-07-2017 IPR005543 PASTA domain GTHT12_RS06115 17c0c7c20c06e907772858da64d832b8 665 Pfam PF03793 PASTA domain 444 504 2.0E-10 T 06-07-2017 IPR005543 PASTA domain GTHT12_RS06115 17c0c7c20c06e907772858da64d832b8 665 Pfam PF03793 PASTA domain 511 571 1.7E-16 T 06-07-2017 IPR005543 PASTA domain GTHT12_RS06115 17c0c7c20c06e907772858da64d832b8 665 Gene3D G3DSA:3.30.200.20 3 77 7.2E-28 T 06-07-2017 GTHT12_RS06115 17c0c7c20c06e907772858da64d832b8 665 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 130 142 - T 06-07-2017 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 GTHT12_RS06115 17c0c7c20c06e907772858da64d832b8 665 Pfam PF00069 Protein kinase domain 11 263 1.2E-56 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 GTHT12_RS06115 17c0c7c20c06e907772858da64d832b8 665 SUPERFAMILY SSF56112 7 269 3.91E-87 T 06-07-2017 IPR011009 Protein kinase-like domain GTHT12_RS06115 17c0c7c20c06e907772858da64d832b8 665 Gene3D G3DSA:1.10.510.10 78 265 4.8E-59 T 06-07-2017 GTHT12_RS06060 2c72a866be1f1d9b13ebb02301ef0295 291 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 291 4.8E-92 T 06-07-2017 IPR005229 Conserved hypothetical protein CHP00255 GTHT12_RS06060 2c72a866be1f1d9b13ebb02301ef0295 291 Pfam PF03755 YicC-like family, N-terminal region 2 156 8.3E-41 T 06-07-2017 IPR013527 YicC-like, N-terminal GTHT12_RS06060 2c72a866be1f1d9b13ebb02301ef0295 291 Pfam PF08340 Domain of unknown function (DUF1732) 207 291 1.6E-35 T 06-07-2017 IPR013551 Domain of unknown function DUF1732 GTHT12_RS05650 63a58ad447995f1fc728b68e89198d7e 66 Pfam PF09963 Uncharacterized protein conserved in bacteria (DUF2197) 1 56 2.2E-32 T 06-07-2017 IPR019241 Protein of unknown function DUF2197 GTHT12_RS18005 b46343f6f890a1d80f5e4d29f8e4174e 357 SUPERFAMILY SSF103473 4 355 4.71E-32 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS18005 b46343f6f890a1d80f5e4d29f8e4174e 357 Gene3D G3DSA:1.20.1250.20 206 354 4.0E-14 T 06-07-2017 GTHT12_RS18005 b46343f6f890a1d80f5e4d29f8e4174e 357 Gene3D G3DSA:1.20.1250.20 7 181 6.0E-13 T 06-07-2017 GTHT12_RS18005 b46343f6f890a1d80f5e4d29f8e4174e 357 Pfam PF07690 Major Facilitator Superfamily 207 350 2.1E-15 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS07890 2402e0cbf01fca6da3ca4e6a5f8c8e8e 408 SMART SM00919 161 385 4.1E-128 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 GTHT12_RS07890 2402e0cbf01fca6da3ca4e6a5f8c8e8e 408 PIRSF PIRSF000106 33 407 7.4E-86 T 06-07-2017 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 GTHT12_RS07890 2402e0cbf01fca6da3ca4e6a5f8c8e8e 408 SMART SM01274 16 149 2.7E-81 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 GTHT12_RS07890 2402e0cbf01fca6da3ca4e6a5f8c8e8e 408 SUPERFAMILY SSF51735 161 397 4.36E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS07890 2402e0cbf01fca6da3ca4e6a5f8c8e8e 408 Gene3D G3DSA:3.40.50.10380 5 158 2.6E-54 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 GTHT12_RS07890 2402e0cbf01fca6da3ca4e6a5f8c8e8e 408 SUPERFAMILY SSF53223 7 159 3.88E-55 T 06-07-2017 GTHT12_RS07890 2402e0cbf01fca6da3ca4e6a5f8c8e8e 408 Gene3D G3DSA:3.40.50.720 159 397 7.1E-84 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS07890 2402e0cbf01fca6da3ca4e6a5f8c8e8e 408 Pfam PF03949 Malic enzyme, NAD binding domain 163 384 4.5E-23 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 GTHT12_RS07890 2402e0cbf01fca6da3ca4e6a5f8c8e8e 408 Pfam PF00390 Malic enzyme, N-terminal domain 18 112 1.1E-21 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 GTHT12_RS13025 7497a7e850d0e99492d9e951612a68ce 198 Pfam PF08279 HTH domain 3 48 7.0E-10 T 06-07-2017 IPR013196 Helix-turn-helix, type 11 GTHT12_RS13025 7497a7e850d0e99492d9e951612a68ce 198 SUPERFAMILY SSF46785 2 65 1.16E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS13025 7497a7e850d0e99492d9e951612a68ce 198 Pfam PF00571 CBS domain 74 120 1.2E-7 T 06-07-2017 IPR000644 CBS domain GTHT12_RS13025 7497a7e850d0e99492d9e951612a68ce 198 Pfam PF00571 CBS domain 134 189 7.5E-7 T 06-07-2017 IPR000644 CBS domain GTHT12_RS13025 7497a7e850d0e99492d9e951612a68ce 198 SMART SM00116 73 121 0.021 T 06-07-2017 IPR000644 CBS domain GTHT12_RS13025 7497a7e850d0e99492d9e951612a68ce 198 SMART SM00116 140 191 0.034 T 06-07-2017 IPR000644 CBS domain GTHT12_RS13025 7497a7e850d0e99492d9e951612a68ce 198 PIRSF PIRSF026546 1 197 1.1E-97 T 06-07-2017 IPR016842 Protein of unknown function UCP026546, HtH-CBS GTHT12_RS13025 7497a7e850d0e99492d9e951612a68ce 198 Gene3D G3DSA:1.10.10.10 1 51 2.7E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS13025 7497a7e850d0e99492d9e951612a68ce 198 SUPERFAMILY SSF54631 57 192 1.89E-24 T 06-07-2017 GTHT12_RS13025 7497a7e850d0e99492d9e951612a68ce 198 Gene3D G3DSA:3.10.580.10 74 190 5.7E-20 T 06-07-2017 GTHT12_RS03285 c671aae8df1106043161af3369dcd5b0 380 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 188 199 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GTHT12_RS03285 c671aae8df1106043161af3369dcd5b0 380 Pfam PF08331 Domain of unknown function (DUF1730) 57 135 4.6E-20 T 06-07-2017 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 GTHT12_RS03285 c671aae8df1106043161af3369dcd5b0 380 Pfam PF13646 HEAT repeats 300 372 2.1E-13 T 06-07-2017 GTHT12_RS03285 c671aae8df1106043161af3369dcd5b0 380 Gene3D G3DSA:1.25.10.10 266 372 6.2E-11 T 06-07-2017 IPR011989 Armadillo-like helical GTHT12_RS03285 c671aae8df1106043161af3369dcd5b0 380 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 3 309 43.989 T 06-07-2017 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 GTHT12_RS03285 c671aae8df1106043161af3369dcd5b0 380 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 11 342 9.0E-133 T 06-07-2017 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 GTHT12_RS03285 c671aae8df1106043161af3369dcd5b0 380 Gene3D G3DSA:3.30.70.20 185 250 4.4E-7 T 06-07-2017 GTHT12_RS03285 c671aae8df1106043161af3369dcd5b0 380 SMART SM00567 E-Z type HEAT repeats 330 359 0.065 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 GTHT12_RS03285 c671aae8df1106043161af3369dcd5b0 380 SMART SM00567 E-Z type HEAT repeats 298 327 24.0 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 GTHT12_RS03285 c671aae8df1106043161af3369dcd5b0 380 SUPERFAMILY SSF54862 164 251 1.26E-15 T 06-07-2017 GTHT12_RS03285 c671aae8df1106043161af3369dcd5b0 380 Pfam PF13484 4Fe-4S double cluster binding domain 187 250 8.7E-17 T 06-07-2017 GTHT12_RS03285 c671aae8df1106043161af3369dcd5b0 380 SUPERFAMILY SSF48371 298 373 1.63E-12 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 GTHT12_RS14950 6ceda16046bbe32093d1b016fcb26197 506 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 15 497 1.7E-225 T 06-07-2017 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 GTHT12_RS14950 6ceda16046bbe32093d1b016fcb26197 506 SUPERFAMILY SSF100950 7 225 7.44E-65 T 06-07-2017 GTHT12_RS14950 6ceda16046bbe32093d1b016fcb26197 506 Gene3D G3DSA:3.40.810.20 228 492 9.6E-81 T 06-07-2017 GTHT12_RS14950 6ceda16046bbe32093d1b016fcb26197 506 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 323 466 9.7E-42 T 06-07-2017 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain GTHT12_RS14950 6ceda16046bbe32093d1b016fcb26197 506 Gene3D G3DSA:3.40.1080.10 14 223 4.6E-39 T 06-07-2017 GTHT12_RS14950 6ceda16046bbe32093d1b016fcb26197 506 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 18 173 5.7E-21 T 06-07-2017 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 GTHT12_RS14950 6ceda16046bbe32093d1b016fcb26197 506 SUPERFAMILY SSF100950 228 498 1.94E-86 T 06-07-2017 GTHT12_RS16905 81ca8b03532b4ae901faf8ccec442d42 445 Pfam PF04055 Radical SAM superfamily 95 231 3.3E-11 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 GTHT12_RS16905 81ca8b03532b4ae901faf8ccec442d42 445 SUPERFAMILY SSF102114 87 403 9.29E-35 T 06-07-2017 GTHT12_RS16905 81ca8b03532b4ae901faf8ccec442d42 445 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 332 414 2.3E-10 T 06-07-2017 IPR023885 4Fe4S-binding SPASM domain GTHT12_RS16905 81ca8b03532b4ae901faf8ccec442d42 445 Gene3D G3DSA:3.20.20.70 85 408 1.9E-36 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS14150 903589fb4a2b065bdc518d403abaa1f0 173 Gene3D G3DSA:3.10.20.80 3 79 1.4E-37 T 06-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 GTHT12_RS14150 903589fb4a2b065bdc518d403abaa1f0 173 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 84 169 5.0E-39 T 06-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 GTHT12_RS14150 903589fb4a2b065bdc518d403abaa1f0 173 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 8 77 8.7E-35 T 06-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 GTHT12_RS14150 903589fb4a2b065bdc518d403abaa1f0 173 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 2 171 32.045 T 06-07-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 GTHT12_RS14150 903589fb4a2b065bdc518d403abaa1f0 173 SUPERFAMILY SSF55200 83 171 9.68E-34 T 06-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 GTHT12_RS14150 903589fb4a2b065bdc518d403abaa1f0 173 ProSitePatterns PS00938 Initiation factor 3 signature. 59 72 - T 06-07-2017 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 GTHT12_RS14150 903589fb4a2b065bdc518d403abaa1f0 173 Gene3D G3DSA:3.30.110.10 80 171 8.8E-40 T 06-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 GTHT12_RS14150 903589fb4a2b065bdc518d403abaa1f0 173 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 8 170 4.6E-77 T 06-07-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 GTHT12_RS14150 903589fb4a2b065bdc518d403abaa1f0 173 SUPERFAMILY SSF54364 6 79 1.05E-30 T 06-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 GTHT12_RS12770 3536f3502bed04126c135d3355dca8fb 145 PIRSF PIRSF021292 1 145 1.8E-44 T 06-07-2017 IPR016785 ComG operon protein 4 GO:0030420 GTHT12_RS12770 3536f3502bed04126c135d3355dca8fb 145 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site GTHT12_RS12770 3536f3502bed04126c135d3355dca8fb 145 SUPERFAMILY SSF54523 7 122 4.39E-12 T 06-07-2017 GTHT12_RS12770 3536f3502bed04126c135d3355dca8fb 145 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 3 26 2.8E-6 T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site GTHT12_RS12770 3536f3502bed04126c135d3355dca8fb 145 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 27 5.6E-7 T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site GTHT12_RS12140 4e4a03519b76d88ce11f704de8b06ce4 492 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 29 480 1.9E-155 T 06-07-2017 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 GTHT12_RS12140 4e4a03519b76d88ce11f704de8b06ce4 492 PIRSF PIRSF005690 8 492 2.4E-137 T 06-07-2017 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 GTHT12_RS14055 c5a95efcb729509c69ff32143af48674 313 SUPERFAMILY SSF53098 97 309 1.4E-49 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS14055 c5a95efcb729509c69ff32143af48674 313 TIGRFAM TIGR00716 rnhC: ribonuclease HIII 13 302 5.3E-81 T 06-07-2017 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 GTHT12_RS14055 c5a95efcb729509c69ff32143af48674 313 Gene3D G3DSA:3.30.420.10 98 261 1.1E-38 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS14055 c5a95efcb729509c69ff32143af48674 313 Hamap MF_00053 Ribonuclease HIII [rnhC]. 1 310 32.2 T 06-07-2017 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 GTHT12_RS14055 c5a95efcb729509c69ff32143af48674 313 Pfam PF11858 Domain of unknown function (DUF3378) 3 77 1.5E-24 T 06-07-2017 IPR024568 Ribonuclease HIII, N-terminal GTHT12_RS14055 c5a95efcb729509c69ff32143af48674 313 Pfam PF01351 Ribonuclease HII 98 303 1.0E-43 T 06-07-2017 IPR024567 Ribonuclease HII/HIII domain GTHT12_RS14055 c5a95efcb729509c69ff32143af48674 313 PIRSF PIRSF037748 1 311 2.6E-113 T 06-07-2017 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 GTHT12_RS15445 b046c794a2fd2d0928cf1290381c19ee 109 SUPERFAMILY SSF52833 2 107 4.7E-44 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS15445 b046c794a2fd2d0928cf1290381c19ee 109 Gene3D G3DSA:3.40.30.30 2 107 2.7E-47 T 06-07-2017 IPR009190 Protein of unknown function DUF1462 GTHT12_RS15445 b046c794a2fd2d0928cf1290381c19ee 109 Pfam PF07315 Protein of unknown function (DUF1462) 9 102 4.7E-41 T 06-07-2017 IPR009190 Protein of unknown function DUF1462 GTHT12_RS15445 b046c794a2fd2d0928cf1290381c19ee 109 PIRSF PIRSF010603 2 108 9.8E-44 T 06-07-2017 IPR009190 Protein of unknown function DUF1462 GTHT12_RS05815 cb286b104e6672e422daca0bf0403b43 251 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 216 5.0E-40 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 GTHT12_RS05815 cb286b104e6672e422daca0bf0403b43 251 SUPERFAMILY SSF52096 4 251 6.59E-60 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS05815 cb286b104e6672e422daca0bf0403b43 251 Gene3D G3DSA:3.90.226.10 5 251 1.7E-57 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS11720 1fd1c33a4c59930092659de5d7c8052d 240 ProDom PD119161 YPHF BH1644 PROTEINS PRECURSOR ORF1 RBL05088 SIGNAL SIMILAR 17 237 7.0E-119 T 06-07-2017 GTHT12_RS13725 ab0c0557e7a8a10eaf0cedb1ad6888bb 351 SUPERFAMILY SSF52540 4 338 1.77E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13725 ab0c0557e7a8a10eaf0cedb1ad6888bb 351 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 4 337 3.2E-146 T 06-07-2017 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 GTHT12_RS13725 ab0c0557e7a8a10eaf0cedb1ad6888bb 351 Pfam PF00437 Type II/IV secretion system protein 117 266 1.4E-42 T 06-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 GTHT12_RS13725 ab0c0557e7a8a10eaf0cedb1ad6888bb 351 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 195 209 - T 06-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 GTHT12_RS13725 ab0c0557e7a8a10eaf0cedb1ad6888bb 351 SMART SM00382 124 258 2.0E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS13725 ab0c0557e7a8a10eaf0cedb1ad6888bb 351 Gene3D G3DSA:3.40.50.300 102 341 7.5E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16930 8151fe642ec869d29526ed8f86a09801 456 PIRSF PIRSF002746 4 456 6.0E-145 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 GTHT12_RS16930 8151fe642ec869d29526ed8f86a09801 456 Pfam PF02447 GntP family permease 9 452 1.7E-133 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 GTHT12_RS16930 8151fe642ec869d29526ed8f86a09801 456 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 12 453 2.8E-103 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 GTHT12_RS01645 1bda70c6c0056152b40de7262c349749 430 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 327 415 5.1E-27 T 06-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 GTHT12_RS01645 1bda70c6c0056152b40de7262c349749 430 SMART SM01210 325 417 4.2E-43 T 06-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 GTHT12_RS01645 1bda70c6c0056152b40de7262c349749 430 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 418 4.2E-167 T 06-07-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 GTHT12_RS01645 1bda70c6c0056152b40de7262c349749 430 Gene3D G3DSA:3.30.470.20 189 322 1.4E-59 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 GTHT12_RS01645 1bda70c6c0056152b40de7262c349749 430 SMART SM01209 101 293 4.5E-135 T 06-07-2017 GTHT12_RS01645 1bda70c6c0056152b40de7262c349749 430 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 7.0E-34 T 06-07-2017 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 GTHT12_RS01645 1bda70c6c0056152b40de7262c349749 430 SUPERFAMILY SSF52440 1 101 1.4E-34 T 06-07-2017 IPR016185 Pre-ATP-grasp domain GTHT12_RS01645 1bda70c6c0056152b40de7262c349749 430 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 287 294 - T 06-07-2017 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 GTHT12_RS01645 1bda70c6c0056152b40de7262c349749 430 SUPERFAMILY SSF51246 324 417 6.36E-29 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GTHT12_RS01645 1bda70c6c0056152b40de7262c349749 430 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 417 43.952 T 06-07-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 GTHT12_RS01645 1bda70c6c0056152b40de7262c349749 430 Gene3D G3DSA:3.30.1490.20 120 188 7.6E-30 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GTHT12_RS01645 1bda70c6c0056152b40de7262c349749 430 Gene3D G3DSA:3.40.50.20 2 93 1.4E-36 T 06-07-2017 IPR016185 Pre-ATP-grasp domain GTHT12_RS01645 1bda70c6c0056152b40de7262c349749 430 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 293 1.7E-82 T 06-07-2017 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 GTHT12_RS01645 1bda70c6c0056152b40de7262c349749 430 SUPERFAMILY SSF56059 102 320 5.13E-66 T 06-07-2017 GTHT12_RS01645 1bda70c6c0056152b40de7262c349749 430 Gene3D G3DSA:3.90.600.10 325 417 7.3E-32 T 06-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 GTHT12_RS08410 b4180dae94d6be7c091221cc30dfdf16 452 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 15 448 2.0E-162 T 06-07-2017 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GTHT12_RS08410 b4180dae94d6be7c091221cc30dfdf16 452 Gene3D G3DSA:3.10.20.70 15 117 8.9E-34 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GTHT12_RS08410 b4180dae94d6be7c091221cc30dfdf16 452 SUPERFAMILY SSF54368 15 113 2.22E-27 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GTHT12_RS08410 b4180dae94d6be7c091221cc30dfdf16 452 Pfam PF00120 Glutamine synthetase, catalytic domain 115 448 1.5E-135 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GTHT12_RS08410 b4180dae94d6be7c091221cc30dfdf16 452 SMART SM01230 114 362 3.4E-133 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GTHT12_RS08410 b4180dae94d6be7c091221cc30dfdf16 452 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 242 257 - T 06-07-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 GTHT12_RS08410 b4180dae94d6be7c091221cc30dfdf16 452 SUPERFAMILY SSF55931 114 448 8.04E-123 T 06-07-2017 GTHT12_RS08410 b4180dae94d6be7c091221cc30dfdf16 452 Gene3D G3DSA:3.30.590.10 118 439 1.0E-123 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 GTHT12_RS08410 b4180dae94d6be7c091221cc30dfdf16 452 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 26 108 1.6E-25 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 GTHT12_RS13655 ebacea1e6fa5e61a9f7477e364824b5b 230 Gene3D G3DSA:2.160.20.70 92 215 8.9E-38 T 06-07-2017 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 GTHT12_RS13655 ebacea1e6fa5e61a9f7477e364824b5b 230 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 111 210 1.2E-31 T 06-07-2017 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 GTHT12_RS13655 ebacea1e6fa5e61a9f7477e364824b5b 230 SUPERFAMILY SSF63848 109 209 7.19E-31 T 06-07-2017 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 GTHT12_RS13655 ebacea1e6fa5e61a9f7477e364824b5b 230 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 11 213 1.2E-38 T 06-07-2017 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 GTHT12_RS13655 ebacea1e6fa5e61a9f7477e364824b5b 230 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 11 214 22.3 T 06-07-2017 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 GTHT12_RS16385 ee8cb7027d96b79cad16d8b6ea31537c 131 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 67 2.5E-23 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 GTHT12_RS16385 ee8cb7027d96b79cad16d8b6ea31537c 131 Pfam PF01467 Cytidylyltransferase-like 5 123 8.1E-23 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 GTHT12_RS16385 ee8cb7027d96b79cad16d8b6ea31537c 131 Gene3D G3DSA:3.40.50.620 1 127 1.4E-38 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS16385 ee8cb7027d96b79cad16d8b6ea31537c 131 TIGRFAM TIGR01518 g3p_cytidyltrns: glycerol-3-phosphate cytidylyltransferase 4 126 1.9E-62 T 06-07-2017 IPR006409 Glycerol-3-phosphate cytidylyltransferase GO:0005737|GO:0019350|GO:0046872|GO:0047348 KEGG: 00564+2.7.7.39 GTHT12_RS16385 ee8cb7027d96b79cad16d8b6ea31537c 131 SUPERFAMILY SSF52374 1 124 3.84E-36 T 06-07-2017 GTHT12_RS16490 f387dc0cf5e3b56f1b39126d79bdf6c1 323 SUPERFAMILY SSF161098 73 311 6.93E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS16490 f387dc0cf5e3b56f1b39126d79bdf6c1 323 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 313 5.6E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS16490 f387dc0cf5e3b56f1b39126d79bdf6c1 323 Gene3D G3DSA:1.10.3720.10 79 322 2.4E-60 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS03785 0dfd2cdce7c93c73f488ee426a6863ae 1172 Gene3D G3DSA:3.40.50.300 293 394 9.4E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03785 0dfd2cdce7c93c73f488ee426a6863ae 1172 Gene3D G3DSA:3.40.50.300 593 696 9.4E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03785 0dfd2cdce7c93c73f488ee426a6863ae 1172 TIGRFAM TIGR02773 addB_Gpos: helicase-exonuclease AddAB, AddB subunit 6 1170 0.0 T 06-07-2017 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 GTHT12_RS03785 0dfd2cdce7c93c73f488ee426a6863ae 1172 SUPERFAMILY SSF52540 300 757 3.19E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03785 0dfd2cdce7c93c73f488ee426a6863ae 1172 Hamap MF_01452 ATP-dependent helicase/deoxyribonuclease subunit B [addB]. 6 1171 65.503 T 06-07-2017 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 GTHT12_RS03785 0dfd2cdce7c93c73f488ee426a6863ae 1172 SUPERFAMILY SSF52540 9 239 2.42E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03785 0dfd2cdce7c93c73f488ee426a6863ae 1172 Pfam PF12705 PD-(D/E)XK nuclease superfamily 797 1140 1.8E-61 T 06-07-2017 GTHT12_RS05080 ac9a41a8eb853dd1c5676cd6ab0d84e3 183 SUPERFAMILY SSF51735 2 83 1.08E-7 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS05080 ac9a41a8eb853dd1c5676cd6ab0d84e3 183 Gene3D G3DSA:3.40.50.720 10 81 1.5E-4 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS12450 9680a14e0c903a784100c48e0a428f43 299 PIRSF PIRSF000428 1 299 8.5E-88 T 06-07-2017 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 GTHT12_RS12450 9680a14e0c903a784100c48e0a428f43 299 TIGRFAM TIGR02706 P_butyryltrans: phosphate butyryltransferase 4 297 7.5E-141 T 06-07-2017 IPR014079 Phosphate butyryltransferase GO:0016740|GO:0019605|GO:0050182 KEGG: 00650+2.3.1.19 GTHT12_RS12450 9680a14e0c903a784100c48e0a428f43 299 SUPERFAMILY SSF53659 5 297 3.91E-70 T 06-07-2017 GTHT12_RS12450 9680a14e0c903a784100c48e0a428f43 299 Pfam PF01515 Phosphate acetyl/butaryl transferase 67 294 5.7E-51 T 06-07-2017 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 GTHT12_RS12450 9680a14e0c903a784100c48e0a428f43 299 Gene3D G3DSA:3.40.50.10750 111 270 2.9E-50 T 06-07-2017 GTHT12_RS13615 d639d198737300799e9a064c5ee9b03b 433 SUPERFAMILY SSF102741 356 428 5.36E-25 T 06-07-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 GTHT12_RS13615 d639d198737300799e9a064c5ee9b03b 433 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 328 4.9E-147 T 06-07-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 GTHT12_RS13615 d639d198737300799e9a064c5ee9b03b 433 Gene3D G3DSA:3.40.50.300 159 330 1.1E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13615 d639d198737300799e9a064c5ee9b03b 433 SUPERFAMILY SSF52540 160 336 6.27E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13615 d639d198737300799e9a064c5ee9b03b 433 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 160 320 4.0E-14 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 GTHT12_RS13615 d639d198737300799e9a064c5ee9b03b 433 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 1.0E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS13615 d639d198737300799e9a064c5ee9b03b 433 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 1.0E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS13615 d639d198737300799e9a064c5ee9b03b 433 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 1.0E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS13615 d639d198737300799e9a064c5ee9b03b 433 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 1.0E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS13615 d639d198737300799e9a064c5ee9b03b 433 Pfam PF09269 Domain of unknown function (DUF1967) 358 426 7.0E-28 T 06-07-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 GTHT12_RS13615 d639d198737300799e9a064c5ee9b03b 433 Pfam PF01018 GTP1/OBG 2 157 1.9E-65 T 06-07-2017 IPR006169 GTP1/OBG domain GO:0005525 GTHT12_RS13615 d639d198737300799e9a064c5ee9b03b 433 Pfam PF01926 50S ribosome-binding GTPase 160 283 2.9E-22 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS13615 d639d198737300799e9a064c5ee9b03b 433 Hamap MF_01454 GTPase Obg [obg]. 1 329 49.518 T 06-07-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 GTHT12_RS13615 d639d198737300799e9a064c5ee9b03b 433 SUPERFAMILY SSF82051 1 157 8.37E-59 T 06-07-2017 IPR006169 GTP1/OBG domain GO:0005525 GTHT12_RS13615 d639d198737300799e9a064c5ee9b03b 433 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 06-07-2017 IPR006074 GTP1/OBG, conserved site GO:0005525 GTHT12_RS13615 d639d198737300799e9a064c5ee9b03b 433 Gene3D G3DSA:2.70.210.12 1 155 4.7E-62 T 06-07-2017 IPR006169 GTP1/OBG domain GO:0005525 GTHT12_RS13615 d639d198737300799e9a064c5ee9b03b 433 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 358 427 1.5E-27 T 06-07-2017 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 GTHT12_RS12595 22b9a37214c5009e1c1394d912b944f7 306 TIGRFAM TIGR02858 spore_III_AA: stage III sporulation protein AA 27 291 2.7E-115 T 06-07-2017 IPR014217 Sporulation stage III, protein AA GTHT12_RS12595 22b9a37214c5009e1c1394d912b944f7 306 Pfam PF00437 Type II/IV secretion system protein 139 270 5.0E-8 T 06-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 GTHT12_RS12595 22b9a37214c5009e1c1394d912b944f7 306 Gene3D G3DSA:3.40.50.300 138 260 3.1E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12595 22b9a37214c5009e1c1394d912b944f7 306 SUPERFAMILY SSF52540 39 259 9.96E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12595 22b9a37214c5009e1c1394d912b944f7 306 SMART SM00382 134 303 9.2E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS17070 845fc424967099acd936ee6347e986a2 508 SUPERFAMILY SSF52540 191 497 2.63E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17070 845fc424967099acd936ee6347e986a2 508 SUPERFAMILY SSF54211 5 169 8.34E-33 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS17070 845fc424967099acd936ee6347e986a2 508 SMART SM00382 214 374 3.3E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS17070 845fc424967099acd936ee6347e986a2 508 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 402 495 1.1E-20 T 06-07-2017 IPR025158 Mg chelatase-related protein, C-terminal domain GTHT12_RS17070 845fc424967099acd936ee6347e986a2 508 Gene3D G3DSA:3.30.230.10 6 168 1.2E-30 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GTHT12_RS17070 845fc424967099acd936ee6347e986a2 508 Gene3D G3DSA:3.40.50.300 192 386 6.6E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17070 845fc424967099acd936ee6347e986a2 508 Pfam PF13541 Subunit ChlI of Mg-chelatase 20 140 1.2E-31 T 06-07-2017 GTHT12_RS17070 845fc424967099acd936ee6347e986a2 508 Pfam PF01078 Magnesium chelatase, subunit ChlI 194 391 1.0E-84 T 06-07-2017 IPR000523 Magnesium chelatase ChlI domain GTHT12_RS17070 845fc424967099acd936ee6347e986a2 508 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 10 495 9.7E-140 T 06-07-2017 IPR004482 Mg chelatase-related protein GTHT12_RS16445 3e16a58066239486b9f790104464506e 458 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 06-07-2017 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 GTHT12_RS16445 3e16a58066239486b9f790104464506e 458 Pfam PF13840 ACT domain 381 445 3.5E-8 T 06-07-2017 IPR027795 GATS-like ACT domain GTHT12_RS16445 3e16a58066239486b9f790104464506e 458 SUPERFAMILY SSF55021 373 450 1.09E-21 T 06-07-2017 GTHT12_RS16445 3e16a58066239486b9f790104464506e 458 SUPERFAMILY SSF53633 1 290 5.63E-69 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase GTHT12_RS16445 3e16a58066239486b9f790104464506e 458 PIRSF PIRSF000726 1 456 2.1E-82 T 06-07-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 GTHT12_RS16445 3e16a58066239486b9f790104464506e 458 Pfam PF00696 Amino acid kinase family 2 277 1.2E-43 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase GTHT12_RS16445 3e16a58066239486b9f790104464506e 458 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 449 1.4E-87 T 06-07-2017 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 GTHT12_RS16445 3e16a58066239486b9f790104464506e 458 Gene3D G3DSA:3.40.1160.10 1 54 9.1E-56 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase GTHT12_RS16445 3e16a58066239486b9f790104464506e 458 Gene3D G3DSA:3.40.1160.10 105 293 9.1E-56 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase GTHT12_RS16445 3e16a58066239486b9f790104464506e 458 SUPERFAMILY SSF55021 297 360 9.87E-10 T 06-07-2017 GTHT12_RS17565 695b58f5188ee6007511010b74f3da38 288 Pfam PF05175 Methyltransferase small domain 117 198 1.8E-14 T 06-07-2017 IPR007848 Methyltransferase small domain GO:0008168 GTHT12_RS17565 695b58f5188ee6007511010b74f3da38 288 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 5 286 41.647 T 06-07-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 GTHT12_RS17565 695b58f5188ee6007511010b74f3da38 288 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 26 282 2.0E-82 T 06-07-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 GTHT12_RS17565 695b58f5188ee6007511010b74f3da38 288 Gene3D G3DSA:1.10.8.10 4 87 2.2E-18 T 06-07-2017 GTHT12_RS17565 695b58f5188ee6007511010b74f3da38 288 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 189 195 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 GTHT12_RS17565 695b58f5188ee6007511010b74f3da38 288 Gene3D G3DSA:3.40.50.150 89 285 5.7E-62 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS17565 695b58f5188ee6007511010b74f3da38 288 SUPERFAMILY SSF53335 5 283 1.63E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS17565 695b58f5188ee6007511010b74f3da38 288 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 4 287 1.8E-69 T 06-07-2017 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 GTHT12_RS14635 a13e23f2fd4fcd6724256e996614cbfe 201 SUPERFAMILY SSF50249 92 200 1.42E-33 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS14635 a13e23f2fd4fcd6724256e996614cbfe 201 Gene3D G3DSA:2.40.50.140 95 199 4.9E-43 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS14635 a13e23f2fd4fcd6724256e996614cbfe 201 Pfam PF14794 Domain of unknown function (DUF4479) 23 91 1.4E-22 T 06-07-2017 IPR027855 Domain of unknown function DUF4479 GTHT12_RS14635 a13e23f2fd4fcd6724256e996614cbfe 201 Gene3D G3DSA:3.30.1940.10 23 92 1.1E-20 T 06-07-2017 IPR027855 Domain of unknown function DUF4479 GTHT12_RS14635 a13e23f2fd4fcd6724256e996614cbfe 201 Pfam PF01588 Putative tRNA binding domain 96 197 2.6E-27 T 06-07-2017 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 GTHT12_RS00410 78c10ddbb5bf69875af6cb493add15db 294 Gene3D G3DSA:3.20.10.10 132 271 7.3E-44 T 06-07-2017 GTHT12_RS00410 78c10ddbb5bf69875af6cb493add15db 294 Gene3D G3DSA:3.30.470.10 4 121 2.4E-37 T 06-07-2017 GTHT12_RS00410 78c10ddbb5bf69875af6cb493add15db 294 Pfam PF01063 Amino-transferase class IV 32 255 5.6E-54 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 GTHT12_RS00410 78c10ddbb5bf69875af6cb493add15db 294 SUPERFAMILY SSF56752 4 278 2.88E-80 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 GTHT12_RS00410 78c10ddbb5bf69875af6cb493add15db 294 ProSitePatterns PS00770 Aminotransferases class-IV signature. 181 210 - T 06-07-2017 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 GTHT12_RS11315 eda26f70aa0377f2e6260c2d783240c9 36 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 10 29 3.1E-10 T 06-07-2017 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM GTHT12_RS11315 eda26f70aa0377f2e6260c2d783240c9 36 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 9 27 7.0E-9 T 06-07-2017 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM GTHT12_RS17190 7143615b391c3eb891a016990f7f4eb4 592 Gene3D G3DSA:3.30.420.40 374 416 4.3E-19 T 06-07-2017 GTHT12_RS17190 7143615b391c3eb891a016990f7f4eb4 592 Gene3D G3DSA:3.30.420.40 202 241 4.3E-19 T 06-07-2017 GTHT12_RS17190 7143615b391c3eb891a016990f7f4eb4 592 SUPERFAMILY SSF100920 459 579 3.27E-10 T 06-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 GTHT12_RS17190 7143615b391c3eb891a016990f7f4eb4 592 Pfam PF00012 Hsp70 protein 337 570 1.6E-13 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GTHT12_RS17190 7143615b391c3eb891a016990f7f4eb4 592 Pfam PF00012 Hsp70 protein 8 334 4.0E-30 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GTHT12_RS17190 7143615b391c3eb891a016990f7f4eb4 592 SUPERFAMILY SSF53067 5 177 4.54E-32 T 06-07-2017 GTHT12_RS17190 7143615b391c3eb891a016990f7f4eb4 592 PRINTS PR00301 70kDa heat shock protein signature 70 78 4.3E-8 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GTHT12_RS17190 7143615b391c3eb891a016990f7f4eb4 592 PRINTS PR00301 70kDa heat shock protein signature 134 154 4.3E-8 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GTHT12_RS17190 7143615b391c3eb891a016990f7f4eb4 592 PRINTS PR00301 70kDa heat shock protein signature 6 19 4.3E-8 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 GTHT12_RS17190 7143615b391c3eb891a016990f7f4eb4 592 Gene3D G3DSA:2.60.34.10 430 570 6.1E-10 T 06-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 GTHT12_RS17190 7143615b391c3eb891a016990f7f4eb4 592 Gene3D G3DSA:3.30.420.40 5 201 3.7E-34 T 06-07-2017 GTHT12_RS17190 7143615b391c3eb891a016990f7f4eb4 592 SUPERFAMILY SSF53067 307 439 1.3E-31 T 06-07-2017 GTHT12_RS17190 7143615b391c3eb891a016990f7f4eb4 592 SUPERFAMILY SSF53067 197 263 1.3E-31 T 06-07-2017 GTHT12_RS04015 a73a570315c2e45dea05bea0ecd7c008 66 Pfam PF12758 Protein of unknown function (DUF3813) 1 63 9.7E-24 T 06-07-2017 IPR024217 Protein of unknown function DUF3813 GTHT12_RS08635 c43c76211f3acdaa3aa39a21d8605d7f 260 Pfam PF00005 ABC transporter 20 172 4.8E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS08635 c43c76211f3acdaa3aa39a21d8605d7f 260 SMART SM00382 29 221 5.9E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS08635 c43c76211f3acdaa3aa39a21d8605d7f 260 Gene3D G3DSA:3.40.50.300 2 243 1.1E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08635 c43c76211f3acdaa3aa39a21d8605d7f 260 SUPERFAMILY SSF52540 4 236 3.02E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11525 e675007db5a57647aaced916b9216e9e 289 SUPERFAMILY SSF52374 1 281 1.42E-107 T 06-07-2017 GTHT12_RS11525 e675007db5a57647aaced916b9216e9e 289 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 70 3.6E-8 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 GTHT12_RS11525 e675007db5a57647aaced916b9216e9e 289 Pfam PF02569 Pantoate-beta-alanine ligase 3 278 3.0E-103 T 06-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 GTHT12_RS11525 e675007db5a57647aaced916b9216e9e 289 Gene3D G3DSA:3.30.1300.10 175 284 2.4E-35 T 06-07-2017 GTHT12_RS11525 e675007db5a57647aaced916b9216e9e 289 Gene3D G3DSA:3.40.50.620 1 174 1.3E-74 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS11525 e675007db5a57647aaced916b9216e9e 289 Hamap MF_00158 Pantothenate synthetase [panC]. 2 279 39.82 T 06-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 GTHT12_RS11525 e675007db5a57647aaced916b9216e9e 289 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 279 4.5E-116 T 06-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 GTHT12_RS02950 179aff66640c6ada860b75e7f3c7c1a1 263 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 3 261 31.411 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 GTHT12_RS02950 179aff66640c6ada860b75e7f3c7c1a1 263 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 23 261 2.2E-73 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 GTHT12_RS02950 179aff66640c6ada860b75e7f3c7c1a1 263 PIRSF PIRSF015626 4 263 9.6E-78 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 GTHT12_RS02950 179aff66640c6ada860b75e7f3c7c1a1 263 Pfam PF02634 FdhD/NarQ family 28 260 1.8E-75 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 GTHT12_RS02950 179aff66640c6ada860b75e7f3c7c1a1 263 SUPERFAMILY SSF53927 7 261 2.74E-78 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 GTHT12_RS02950 179aff66640c6ada860b75e7f3c7c1a1 263 Gene3D G3DSA:3.10.20.10 29 111 8.0E-22 T 06-07-2017 GTHT12_RS02950 179aff66640c6ada860b75e7f3c7c1a1 263 Gene3D G3DSA:3.40.140.10 129 262 8.3E-51 T 06-07-2017 GTHT12_RS07075 8b276374da4840c1a9e98e294cf9945e 553 TIGRFAM TIGR01228 hutU: urocanate hydratase 8 551 6.4E-300 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 GTHT12_RS07075 8b276374da4840c1a9e98e294cf9945e 553 ProSitePatterns PS01233 Urocanase signature. 439 454 - T 06-07-2017 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 GTHT12_RS07075 8b276374da4840c1a9e98e294cf9945e 553 SUPERFAMILY SSF111326 5 552 6.15E-262 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 GTHT12_RS07075 8b276374da4840c1a9e98e294cf9945e 553 Gene3D G3DSA:3.40.1770.10 6 138 2.1E-155 T 06-07-2017 GTHT12_RS07075 8b276374da4840c1a9e98e294cf9945e 553 Gene3D G3DSA:3.40.1770.10 357 553 2.1E-155 T 06-07-2017 GTHT12_RS07075 8b276374da4840c1a9e98e294cf9945e 553 Gene3D G3DSA:3.40.50.10730 139 346 1.7E-92 T 06-07-2017 GTHT12_RS07075 8b276374da4840c1a9e98e294cf9945e 553 PIRSF PIRSF001423 1 553 3.9E-297 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 GTHT12_RS07075 8b276374da4840c1a9e98e294cf9945e 553 Hamap MF_00577 Urocanate hydratase [hutU]. 4 553 50.74 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 GTHT12_RS07075 8b276374da4840c1a9e98e294cf9945e 553 Pfam PF01175 Urocanase 10 544 2.1E-266 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 GTHT12_RS18330 058eb705d65c473df5762e1203e4cd9d 208 Gene3D G3DSA:1.10.1220.10 2 40 3.9E-5 T 06-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 GTHT12_RS16860 a2bb9afb681f90741bf01fba4cfef476 165 Pfam PF03734 L,D-transpeptidase catalytic domain 57 163 4.8E-18 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 GTHT12_RS16860 a2bb9afb681f90741bf01fba4cfef476 165 SUPERFAMILY SSF141523 56 164 7.46E-33 T 06-07-2017 GTHT12_RS16860 a2bb9afb681f90741bf01fba4cfef476 165 SUPERFAMILY SSF54106 2 47 3.01E-11 T 06-07-2017 IPR018392 LysM domain GTHT12_RS16860 a2bb9afb681f90741bf01fba4cfef476 165 SMART SM00257 3 47 1.3E-14 T 06-07-2017 IPR018392 LysM domain GTHT12_RS16860 a2bb9afb681f90741bf01fba4cfef476 165 Pfam PF01476 LysM domain 4 47 2.2E-13 T 06-07-2017 IPR018392 LysM domain GTHT12_RS16860 a2bb9afb681f90741bf01fba4cfef476 165 Gene3D G3DSA:3.10.350.10 3 47 4.2E-16 T 06-07-2017 IPR018392 LysM domain GTHT12_RS16860 a2bb9afb681f90741bf01fba4cfef476 165 Gene3D G3DSA:2.40.440.10 56 164 3.5E-38 T 06-07-2017 GTHT12_RS07945 46a902855d6d9c5ed63c00f0be13004c 501 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 4 495 4.7E-212 T 06-07-2017 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 GTHT12_RS07945 46a902855d6d9c5ed63c00f0be13004c 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 403 424 1.1E-80 T 06-07-2017 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 GTHT12_RS07945 46a902855d6d9c5ed63c00f0be13004c 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 246 265 1.1E-80 T 06-07-2017 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 GTHT12_RS07945 46a902855d6d9c5ed63c00f0be13004c 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 266 285 1.1E-80 T 06-07-2017 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 GTHT12_RS07945 46a902855d6d9c5ed63c00f0be13004c 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 149 169 1.1E-80 T 06-07-2017 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 GTHT12_RS07945 46a902855d6d9c5ed63c00f0be13004c 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 293 309 1.1E-80 T 06-07-2017 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 GTHT12_RS07945 46a902855d6d9c5ed63c00f0be13004c 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 380 397 1.1E-80 T 06-07-2017 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 GTHT12_RS07945 46a902855d6d9c5ed63c00f0be13004c 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 229 245 1.1E-80 T 06-07-2017 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 GTHT12_RS07945 46a902855d6d9c5ed63c00f0be13004c 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 447 465 1.1E-80 T 06-07-2017 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 GTHT12_RS07945 46a902855d6d9c5ed63c00f0be13004c 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 334 353 1.1E-80 T 06-07-2017 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 GTHT12_RS07945 46a902855d6d9c5ed63c00f0be13004c 501 PIRSF PIRSF006615 1 501 3.2E-197 T 06-07-2017 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 GTHT12_RS07945 46a902855d6d9c5ed63c00f0be13004c 501 SUPERFAMILY SSF55486 7 495 4.76E-120 T 06-07-2017 GTHT12_RS16285 6bae3a95f988af9fe0098e3c8b705909 281 SUPERFAMILY SSF82549 2 279 2.3E-96 T 06-07-2017 GTHT12_RS16285 6bae3a95f988af9fe0098e3c8b705909 281 Gene3D G3DSA:3.30.1180.10 153 280 9.4E-44 T 06-07-2017 GTHT12_RS16285 6bae3a95f988af9fe0098e3c8b705909 281 Gene3D G3DSA:3.40.50.10170 2 151 4.7E-51 T 06-07-2017 GTHT12_RS16285 6bae3a95f988af9fe0098e3c8b705909 281 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 279 3.0E-101 T 06-07-2017 IPR003797 DegV GTHT12_RS16285 6bae3a95f988af9fe0098e3c8b705909 281 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 279 2.1E-107 T 06-07-2017 IPR003797 DegV GTHT12_RS02280 b81f1e1870e97c32834c90d9b4a482b6 493 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 GTHT12_RS02280 b81f1e1870e97c32834c90d9b4a482b6 493 SUPERFAMILY SSF53720 5 480 1.7E-171 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GTHT12_RS02280 b81f1e1870e97c32834c90d9b4a482b6 493 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 246 253 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 GTHT12_RS02280 b81f1e1870e97c32834c90d9b4a482b6 493 Gene3D G3DSA:3.40.309.10 261 450 1.8E-71 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 GTHT12_RS02280 b81f1e1870e97c32834c90d9b4a482b6 493 Pfam PF00171 Aldehyde dehydrogenase family 16 476 4.2E-178 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS02280 b81f1e1870e97c32834c90d9b4a482b6 493 Gene3D G3DSA:3.40.605.10 4 260 4.9E-105 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS04595 4ff502140f34f0396807a9bd29fd250f 232 SUPERFAMILY SSF53448 11 227 2.38E-57 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS04595 4ff502140f34f0396807a9bd29fd250f 232 Gene3D G3DSA:3.90.550.10 10 226 2.1E-57 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS04595 4ff502140f34f0396807a9bd29fd250f 232 Pfam PF00535 Glycosyl transferase family 2 12 180 1.4E-34 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 GTHT12_RS17670 2902ee291b206fba5f0d6fc049972ab0 396 Gene3D G3DSA:3.30.870.10 36 206 5.4E-43 T 06-07-2017 GTHT12_RS17670 2902ee291b206fba5f0d6fc049972ab0 396 SUPERFAMILY SSF56024 227 381 3.36E-42 T 06-07-2017 GTHT12_RS17670 2902ee291b206fba5f0d6fc049972ab0 396 SMART SM00155 137 164 4.9E-4 T 06-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 GTHT12_RS17670 2902ee291b206fba5f0d6fc049972ab0 396 SMART SM00155 309 336 1.6E-5 T 06-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 GTHT12_RS17670 2902ee291b206fba5f0d6fc049972ab0 396 Gene3D G3DSA:3.30.870.10 207 373 4.4E-38 T 06-07-2017 GTHT12_RS17670 2902ee291b206fba5f0d6fc049972ab0 396 Pfam PF13091 PLD-like domain 56 197 4.2E-14 T 06-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 GTHT12_RS17670 2902ee291b206fba5f0d6fc049972ab0 396 Pfam PF13091 PLD-like domain 237 363 5.0E-26 T 06-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 GTHT12_RS17670 2902ee291b206fba5f0d6fc049972ab0 396 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 35 394 8.3E-101 T 06-07-2017 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 GTHT12_RS17670 2902ee291b206fba5f0d6fc049972ab0 396 SUPERFAMILY SSF56024 37 220 7.22E-47 T 06-07-2017 GTHT12_RS03345 b8d8f550cbb3cd49a516188f7e6b5884 421 Pfam PF00375 Sodium:dicarboxylate symporter family 8 400 5.8E-120 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS03345 b8d8f550cbb3cd49a516188f7e6b5884 421 PRINTS PR00173 Glutamate-aspartate symporter signature 43 63 2.1E-32 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS03345 b8d8f550cbb3cd49a516188f7e6b5884 421 PRINTS PR00173 Glutamate-aspartate symporter signature 2 22 2.1E-32 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS03345 b8d8f550cbb3cd49a516188f7e6b5884 421 PRINTS PR00173 Glutamate-aspartate symporter signature 326 345 2.1E-32 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS03345 b8d8f550cbb3cd49a516188f7e6b5884 421 PRINTS PR00173 Glutamate-aspartate symporter signature 73 98 2.1E-32 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS03345 b8d8f550cbb3cd49a516188f7e6b5884 421 PRINTS PR00173 Glutamate-aspartate symporter signature 291 317 2.1E-32 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS03345 b8d8f550cbb3cd49a516188f7e6b5884 421 PRINTS PR00173 Glutamate-aspartate symporter signature 144 166 2.1E-32 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS03345 b8d8f550cbb3cd49a516188f7e6b5884 421 Gene3D G3DSA:1.10.3860.10 4 403 1.6E-125 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS03345 b8d8f550cbb3cd49a516188f7e6b5884 421 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 294 317 - T 06-07-2017 IPR018107 Sodium:dicarboxylate symporter, conserved site GTHT12_RS03345 b8d8f550cbb3cd49a516188f7e6b5884 421 SUPERFAMILY SSF118215 8 401 1.27E-123 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS09935 55f56fef1327057d8c95046950cae9c4 63 Gene3D G3DSA:3.30.360.10 14 63 1.2E-6 T 06-07-2017 GTHT12_RS13145 00f91cf3d99e02f403047eff6ab946b8 609 Gene3D G3DSA:3.40.50.300 8 201 2.2E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13145 00f91cf3d99e02f403047eff6ab946b8 609 Gene3D G3DSA:3.30.70.870 301 378 2.2E-27 T 06-07-2017 GTHT12_RS13145 00f91cf3d99e02f403047eff6ab946b8 609 TIGRFAM TIGR01393 lepA: elongation factor 4 12 605 0.0 T 06-07-2017 IPR006297 Elongation factor 4 GO:0005525 GTHT12_RS13145 00f91cf3d99e02f403047eff6ab946b8 609 SMART SM00838 407 495 2.3E-4 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain GTHT12_RS13145 00f91cf3d99e02f403047eff6ab946b8 609 SUPERFAMILY SSF54980 408 503 5.76E-28 T 06-07-2017 IPR009022 Elongation factor G, III-V domain GTHT12_RS13145 00f91cf3d99e02f403047eff6ab946b8 609 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 182 9.0E-20 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 GTHT12_RS13145 00f91cf3d99e02f403047eff6ab946b8 609 Pfam PF00009 Elongation factor Tu GTP binding domain 12 190 2.0E-53 T 06-07-2017 GTHT12_RS13145 00f91cf3d99e02f403047eff6ab946b8 609 SUPERFAMILY SSF52540 6 218 1.91E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13145 00f91cf3d99e02f403047eff6ab946b8 609 SUPERFAMILY SSF50447 191 297 6.63E-29 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain GTHT12_RS13145 00f91cf3d99e02f403047eff6ab946b8 609 SUPERFAMILY SSF54980 301 379 4.68E-19 T 06-07-2017 IPR009022 Elongation factor G, III-V domain GTHT12_RS13145 00f91cf3d99e02f403047eff6ab946b8 609 Gene3D G3DSA:2.40.30.10 202 298 4.3E-31 T 06-07-2017 GTHT12_RS13145 00f91cf3d99e02f403047eff6ab946b8 609 Gene3D G3DSA:3.30.70.240 410 499 1.9E-23 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain GTHT12_RS13145 00f91cf3d99e02f403047eff6ab946b8 609 Pfam PF06421 GTP-binding protein LepA C-terminus 497 603 1.4E-52 T 06-07-2017 IPR013842 GTP-binding protein LepA, C-terminal GTHT12_RS13145 00f91cf3d99e02f403047eff6ab946b8 609 PRINTS PR00315 GTP-binding elongation factor signature 15 28 3.9E-14 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GTHT12_RS13145 00f91cf3d99e02f403047eff6ab946b8 609 PRINTS PR00315 GTP-binding elongation factor signature 83 93 3.9E-14 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GTHT12_RS13145 00f91cf3d99e02f403047eff6ab946b8 609 PRINTS PR00315 GTP-binding elongation factor signature 135 144 3.9E-14 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GTHT12_RS13145 00f91cf3d99e02f403047eff6ab946b8 609 PRINTS PR00315 GTP-binding elongation factor signature 99 110 3.9E-14 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GTHT12_RS13145 00f91cf3d99e02f403047eff6ab946b8 609 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.9E-14 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 GTHT12_RS13145 00f91cf3d99e02f403047eff6ab946b8 609 Pfam PF00679 Elongation factor G C-terminus 408 495 8.7E-26 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain GTHT12_RS13145 00f91cf3d99e02f403047eff6ab946b8 609 Pfam PF03144 Elongation factor Tu domain 2 214 284 6.8E-13 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 GTHT12_RS13145 00f91cf3d99e02f403047eff6ab946b8 609 Hamap MF_00071 Elongation factor 4 [lepA]. 1 607 320.003 T 06-07-2017 IPR006297 Elongation factor 4 GO:0005525 GTHT12_RS17965 973645c69ea528ce881f5d5caee87dc4 412 Gene3D G3DSA:3.30.70.270 246 405 9.3E-35 T 06-07-2017 GTHT12_RS17965 973645c69ea528ce881f5d5caee87dc4 412 SMART SM00267 234 407 3.0E-36 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS17965 973645c69ea528ce881f5d5caee87dc4 412 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 242 406 1.3E-33 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS17965 973645c69ea528ce881f5d5caee87dc4 412 SUPERFAMILY SSF55073 250 404 4.63E-33 T 06-07-2017 IPR029787 Nucleotide cyclase GTHT12_RS17965 973645c69ea528ce881f5d5caee87dc4 412 Pfam PF00990 Diguanylate cyclase, GGDEF domain 245 403 5.7E-31 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS15615 1b1fe77194488c533e7f554cc1d74ee9 283 SUPERFAMILY SSF53850 39 280 1.71E-84 T 06-07-2017 GTHT12_RS15615 1b1fe77194488c533e7f554cc1d74ee9 283 PIRSF PIRSF002854 1 281 5.6E-112 T 06-07-2017 IPR004872 Lipoprotein NlpA family GTHT12_RS15615 1b1fe77194488c533e7f554cc1d74ee9 283 Gene3D G3DSA:3.40.190.10 39 168 2.4E-55 T 06-07-2017 GTHT12_RS15615 1b1fe77194488c533e7f554cc1d74ee9 283 Pfam PF03180 NLPA lipoprotein 40 279 3.7E-93 T 06-07-2017 IPR004872 Lipoprotein NlpA family GTHT12_RS15615 1b1fe77194488c533e7f554cc1d74ee9 283 Gene3D G3DSA:3.40.190.10 176 271 1.9E-5 T 06-07-2017 GTHT12_RS05840 95d5bdc30addef61c9715ba3be7561de 310 SUPERFAMILY SSF81799 113 214 5.49E-36 T 06-07-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GTHT12_RS05840 95d5bdc30addef61c9715ba3be7561de 310 SUPERFAMILY SSF53335 4 112 1.86E-50 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS05840 95d5bdc30addef61c9715ba3be7561de 310 SUPERFAMILY SSF53335 214 309 1.86E-50 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS05840 95d5bdc30addef61c9715ba3be7561de 310 Gene3D G3DSA:3.40.50.150 4 109 2.1E-54 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS05840 95d5bdc30addef61c9715ba3be7561de 310 Gene3D G3DSA:3.40.50.150 217 309 2.1E-54 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS05840 95d5bdc30addef61c9715ba3be7561de 310 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 309 2.7E-128 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GTHT12_RS05840 95d5bdc30addef61c9715ba3be7561de 310 Pfam PF01795 MraW methylase family 2 309 1.4E-135 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GTHT12_RS05840 95d5bdc30addef61c9715ba3be7561de 310 PIRSF PIRSF004486 1 310 1.2E-111 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GTHT12_RS05840 95d5bdc30addef61c9715ba3be7561de 310 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 4 310 40.267 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GTHT12_RS05840 95d5bdc30addef61c9715ba3be7561de 310 Gene3D G3DSA:1.10.150.170 111 216 1.7E-39 T 06-07-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GTHT12_RS09050 e7083b699eb60f5a7b5e881ae37201be 148 Gene3D G3DSA:1.10.10.10 4 139 2.5E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS09050 e7083b699eb60f5a7b5e881ae37201be 148 Pfam PF01047 MarR family 30 87 1.2E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS09050 e7083b699eb60f5a7b5e881ae37201be 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 133 1.6E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS09050 e7083b699eb60f5a7b5e881ae37201be 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 1.6E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS09050 e7083b699eb60f5a7b5e881ae37201be 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 1.6E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS09050 e7083b699eb60f5a7b5e881ae37201be 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 1.6E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS09050 e7083b699eb60f5a7b5e881ae37201be 148 SUPERFAMILY SSF46785 18 136 1.21E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS09050 e7083b699eb60f5a7b5e881ae37201be 148 SMART SM00347 23 123 1.1E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS01880 85067fd292ad081f0bf333c1465a1513 220 SUPERFAMILY SSF52172 1 126 2.28E-36 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS01880 85067fd292ad081f0bf333c1465a1513 220 Pfam PF00072 Response regulator receiver domain 3 113 1.7E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS01880 85067fd292ad081f0bf333c1465a1513 220 SMART SM00448 1 113 8.2E-41 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS01880 85067fd292ad081f0bf333c1465a1513 220 SUPERFAMILY SSF46894 124 218 3.68E-29 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GTHT12_RS01880 85067fd292ad081f0bf333c1465a1513 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 218 4.4E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS01880 85067fd292ad081f0bf333c1465a1513 220 Gene3D G3DSA:3.40.50.2300 1 119 9.7E-34 T 06-07-2017 GTHT12_RS01880 85067fd292ad081f0bf333c1465a1513 220 Gene3D G3DSA:1.10.10.10 125 219 2.2E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS01880 85067fd292ad081f0bf333c1465a1513 220 SMART SM00862 147 218 7.5E-28 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS18890 630e78a5e5012f82828fca1ec8662713 414 SUPERFAMILY SSF53335 113 369 1.3E-55 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS18890 630e78a5e5012f82828fca1ec8662713 414 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 141 147 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 GTHT12_RS18890 630e78a5e5012f82828fca1ec8662713 414 Gene3D G3DSA:3.40.50.150 120 367 1.7E-55 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS18890 630e78a5e5012f82828fca1ec8662713 414 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 299 321 1.2E-21 T 06-07-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 GTHT12_RS18890 630e78a5e5012f82828fca1ec8662713 414 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 138 150 1.2E-21 T 06-07-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 GTHT12_RS18890 630e78a5e5012f82828fca1ec8662713 414 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 322 336 1.2E-21 T 06-07-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 GTHT12_RS18890 630e78a5e5012f82828fca1ec8662713 414 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 173 192 1.2E-21 T 06-07-2017 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 GTHT12_RS18890 630e78a5e5012f82828fca1ec8662713 414 Pfam PF01555 DNA methylase 138 348 6.7E-43 T 06-07-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 GTHT12_RS05850 351b6079146a5141b6a0a1eb8f6ce296 736 SUPERFAMILY SSF54184 657 709 1.83E-12 T 06-07-2017 GTHT12_RS05850 351b6079146a5141b6a0a1eb8f6ce296 736 Pfam PF03793 PASTA domain 657 709 2.2E-10 T 06-07-2017 IPR005543 PASTA domain GTHT12_RS05850 351b6079146a5141b6a0a1eb8f6ce296 736 Pfam PF03793 PASTA domain 602 652 7.4E-6 T 06-07-2017 IPR005543 PASTA domain GTHT12_RS05850 351b6079146a5141b6a0a1eb8f6ce296 736 Pfam PF00905 Penicillin binding protein transpeptidase domain 268 573 2.9E-83 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 GTHT12_RS05850 351b6079146a5141b6a0a1eb8f6ce296 736 SMART SM00740 594 654 1.2E-4 T 06-07-2017 IPR005543 PASTA domain GTHT12_RS05850 351b6079146a5141b6a0a1eb8f6ce296 736 SMART SM00740 655 711 3.4E-7 T 06-07-2017 IPR005543 PASTA domain GTHT12_RS05850 351b6079146a5141b6a0a1eb8f6ce296 736 Gene3D G3DSA:3.90.1310.10 142 246 5.5E-31 T 06-07-2017 GTHT12_RS05850 351b6079146a5141b6a0a1eb8f6ce296 736 SUPERFAMILY SSF56601 190 587 1.18E-95 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS05850 351b6079146a5141b6a0a1eb8f6ce296 736 SUPERFAMILY SSF56519 57 239 4.84E-45 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 GTHT12_RS05850 351b6079146a5141b6a0a1eb8f6ce296 736 SUPERFAMILY SSF54184 600 653 8.63E-12 T 06-07-2017 GTHT12_RS05850 351b6079146a5141b6a0a1eb8f6ce296 736 Gene3D G3DSA:3.40.710.10 247 579 1.8E-93 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS05850 351b6079146a5141b6a0a1eb8f6ce296 736 Pfam PF03717 Penicillin-binding Protein dimerisation domain 59 218 5.5E-23 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 GTHT12_RS08810 9fa9fb482f7144e0d7bc4019c999649e 507 Pfam PF03961 Protein of unknown function (DUF342) 62 334 3.9E-66 T 06-07-2017 IPR005646 Protein of unknown function DUF342 GTHT12_RS07595 fe2b0d7b5786811eeb387a05d3eeadf9 464 Pfam PF07670 Nucleoside recognition 137 225 3.6E-8 T 06-07-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 GTHT12_RS07595 fe2b0d7b5786811eeb387a05d3eeadf9 464 Pfam PF07670 Nucleoside recognition 307 432 1.4E-15 T 06-07-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 GTHT12_RS07595 fe2b0d7b5786811eeb387a05d3eeadf9 464 Pfam PF07664 Ferrous iron transport protein B C terminus 249 297 2.7E-13 T 06-07-2017 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 GTHT12_RS16005 48d6d43a57074f94795fdc5783bc90f4 394 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 15 325 6.2E-100 T 06-07-2017 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 GTHT12_RS16005 48d6d43a57074f94795fdc5783bc90f4 394 PIRSF PIRSF001549 4 384 6.1E-84 T 06-07-2017 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 GTHT12_RS16005 48d6d43a57074f94795fdc5783bc90f4 394 SUPERFAMILY SSF55681 8 329 3.06E-67 T 06-07-2017 GTHT12_RS16005 48d6d43a57074f94795fdc5783bc90f4 394 Pfam PF13393 Histidyl-tRNA synthetase 13 321 4.6E-81 T 06-07-2017 GTHT12_RS16005 48d6d43a57074f94795fdc5783bc90f4 394 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 20 375 33.434 T 06-07-2017 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 GTHT12_RS16005 48d6d43a57074f94795fdc5783bc90f4 394 Gene3D G3DSA:3.30.930.10 23 322 5.5E-81 T 06-07-2017 GTHT12_RS02690 92f388b65927e90ff41df2beef33af15 71 Pfam PF14412 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH 6 48 1.0E-5 T 06-07-2017 IPR032871 AHH domain-containing protein GTHT12_RS17755 44a44e0f4bab27f728f3fa0e359728ae 286 SUPERFAMILY SSF55681 2 270 8.2E-75 T 06-07-2017 GTHT12_RS17755 44a44e0f4bab27f728f3fa0e359728ae 286 Hamap MF_02119 Lipoyl-[GcvH]:protein N-lipoyltransferase [lipL]. 4 277 51.033 T 06-07-2017 IPR024897 Octanoyltransferase LipL GO:0009107|GO:0009249|GO:0016415 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20|MetaCyc: PWY-6987 GTHT12_RS17755 44a44e0f4bab27f728f3fa0e359728ae 286 Gene3D G3DSA:3.90.1550.10 2 268 2.0E-75 T 06-07-2017 GTHT12_RS17755 44a44e0f4bab27f728f3fa0e359728ae 286 Pfam PF03099 Biotin/lipoate A/B protein ligase family 76 182 2.5E-15 T 06-07-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 GTHT12_RS04530 d4f17af70f997a3472499233bcf10f34 68 Pfam PF07870 Protein of unknown function (DUF1657) 7 55 2.8E-18 T 06-07-2017 IPR012452 Protein of unknown function DUF1657 GTHT12_RS07240 f477b450f1ec93a998b6c7d7abf1c019 374 Gene3D G3DSA:3.30.9.10 211 309 1.5E-11 T 06-07-2017 GTHT12_RS07240 f477b450f1ec93a998b6c7d7abf1c019 374 SUPERFAMILY SSF51905 312 366 1.29E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS07240 f477b450f1ec93a998b6c7d7abf1c019 374 SUPERFAMILY SSF51905 4 221 1.29E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS07240 f477b450f1ec93a998b6c7d7abf1c019 374 Gene3D G3DSA:3.50.50.60 312 366 2.0E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS07240 f477b450f1ec93a998b6c7d7abf1c019 374 Gene3D G3DSA:3.50.50.60 4 80 2.0E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS07240 f477b450f1ec93a998b6c7d7abf1c019 374 Gene3D G3DSA:3.50.50.60 141 210 2.0E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS07240 f477b450f1ec93a998b6c7d7abf1c019 374 SUPERFAMILY SSF54373 221 312 3.01E-16 T 06-07-2017 GTHT12_RS07240 f477b450f1ec93a998b6c7d7abf1c019 374 Pfam PF01266 FAD dependent oxidoreductase 4 351 2.2E-52 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 GTHT12_RS13520 b8e06654aa0a7ea7fd7952312f1b7e23 91 Pfam PF02699 Preprotein translocase subunit 7 82 1.3E-30 T 06-07-2017 IPR003849 Preprotein translocase YajC GTHT12_RS13520 b8e06654aa0a7ea7fd7952312f1b7e23 91 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 5 84 7.5E-31 T 06-07-2017 IPR003849 Preprotein translocase YajC GTHT12_RS13520 b8e06654aa0a7ea7fd7952312f1b7e23 91 SMART SM01323 3 85 1.9E-43 T 06-07-2017 IPR003849 Preprotein translocase YajC GTHT12_RS13520 b8e06654aa0a7ea7fd7952312f1b7e23 91 PRINTS PR01853 Bacterial YajC preprotein translocase signature 43 61 1.8E-16 T 06-07-2017 IPR003849 Preprotein translocase YajC GTHT12_RS13520 b8e06654aa0a7ea7fd7952312f1b7e23 91 PRINTS PR01853 Bacterial YajC preprotein translocase signature 5 25 1.8E-16 T 06-07-2017 IPR003849 Preprotein translocase YajC GTHT12_RS13255 113757755ad5e223506faeff022b87f1 263 Pfam PF01618 MotA/TolQ/ExbB proton channel family 102 217 8.4E-27 T 06-07-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 GTHT12_RS13255 113757755ad5e223506faeff022b87f1 263 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 186 203 - T 06-07-2017 IPR000540 Flagellar motor protein MotA, conserved site GTHT12_RS07010 055767455ceb4e383ec4d1e72921ad49 221 Gene3D G3DSA:3.30.420.10 72 212 2.1E-13 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS07010 055767455ceb4e383ec4d1e72921ad49 221 Pfam PF13456 Reverse transcriptase-like 78 205 2.5E-16 T 06-07-2017 GTHT12_RS07010 055767455ceb4e383ec4d1e72921ad49 221 SUPERFAMILY SSF53098 73 211 6.2E-19 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS15435 d296e9b66ea7109b155b699b38088aad 79 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 2 78 3.0E-37 T 06-07-2017 GTHT12_RS15435 d296e9b66ea7109b155b699b38088aad 79 Pfam PF07293 Protein of unknown function (DUF1450) 4 76 1.2E-35 T 06-07-2017 IPR009910 Protein of unknown function DUF1450 GTHT12_RS15435 d296e9b66ea7109b155b699b38088aad 79 Hamap MF_01542 UPF0349 protein . 2 78 28.724 T 06-07-2017 IPR022916 Protein of unknown function UPF0349 GTHT12_RS11925 1c03b8e30138b71e894ea30357be1695 238 Gene3D G3DSA:3.30.1330.10 9 119 8.1E-5 T 06-07-2017 IPR016188 PurM-like, N-terminal domain GTHT12_RS11925 1c03b8e30138b71e894ea30357be1695 238 SUPERFAMILY SSF55326 29 121 4.4E-5 T 06-07-2017 GTHT12_RS12190 897fb0d4a463dc5d6c6e0cd9a26c6a50 116 Pfam PF01740 STAS domain 5 106 3.9E-26 T 06-07-2017 IPR002645 STAS domain GTHT12_RS12190 897fb0d4a463dc5d6c6e0cd9a26c6a50 116 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 106 6.6E-40 T 06-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 GTHT12_RS12190 897fb0d4a463dc5d6c6e0cd9a26c6a50 116 TIGRFAM TIGR02886 spore_II_AA: anti-sigma F factor antagonist 5 110 9.6E-49 T 06-07-2017 IPR014237 Anti-sigma F factor antagonist GO:0006355|GO:0030435|GO:0045152 GTHT12_RS12190 897fb0d4a463dc5d6c6e0cd9a26c6a50 116 Gene3D G3DSA:3.30.750.24 4 113 9.2E-40 T 06-07-2017 IPR002645 STAS domain GTHT12_RS12190 897fb0d4a463dc5d6c6e0cd9a26c6a50 116 SUPERFAMILY SSF52091 4 111 6.08E-32 T 06-07-2017 IPR002645 STAS domain GTHT12_RS07315 2195f9c48f70a954228fbeccad73a70a 298 SUPERFAMILY SSF53850 89 294 5.25E-42 T 06-07-2017 GTHT12_RS07315 2195f9c48f70a954228fbeccad73a70a 298 Pfam PF03466 LysR substrate binding domain 88 292 3.1E-47 T 06-07-2017 IPR005119 LysR, substrate-binding GTHT12_RS07315 2195f9c48f70a954228fbeccad73a70a 298 Gene3D G3DSA:3.40.190.10 87 172 1.4E-22 T 06-07-2017 GTHT12_RS07315 2195f9c48f70a954228fbeccad73a70a 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.4E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GTHT12_RS07315 2195f9c48f70a954228fbeccad73a70a 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.4E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GTHT12_RS07315 2195f9c48f70a954228fbeccad73a70a 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.4E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GTHT12_RS07315 2195f9c48f70a954228fbeccad73a70a 298 Gene3D G3DSA:3.40.190.10 173 263 6.6E-18 T 06-07-2017 GTHT12_RS07315 2195f9c48f70a954228fbeccad73a70a 298 Gene3D G3DSA:1.10.10.10 3 83 5.4E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS07315 2195f9c48f70a954228fbeccad73a70a 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 5.3E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GTHT12_RS07315 2195f9c48f70a954228fbeccad73a70a 298 SUPERFAMILY SSF46785 2 86 5.14E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12465 f0c3ba27164ff8eb9f6776ee3c47d67a 244 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 231 4.3E-51 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 GTHT12_RS12465 f0c3ba27164ff8eb9f6776ee3c47d67a 244 Gene3D G3DSA:3.20.20.190 2 240 3.9E-81 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 GTHT12_RS12465 f0c3ba27164ff8eb9f6776ee3c47d67a 244 SUPERFAMILY SSF51695 1 237 7.12E-80 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 GTHT12_RS09605 e81a53790921ea8a9e193b461612921d 788 PIRSF PIRSF007519 3 788 6.2E-285 T 06-07-2017 IPR012300 Peptidase M6, InhA GTHT12_RS09605 e81a53790921ea8a9e193b461612921d 788 SUPERFAMILY SSF55486 247 292 3.31E-17 T 06-07-2017 GTHT12_RS09605 e81a53790921ea8a9e193b461612921d 788 SUPERFAMILY SSF55486 341 417 3.31E-17 T 06-07-2017 GTHT12_RS09605 e81a53790921ea8a9e193b461612921d 788 Pfam PF05547 Immune inhibitor A peptidase M6 138 783 3.1E-254 T 06-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 GTHT12_RS09605 e81a53790921ea8a9e193b461612921d 788 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 170 478 1.3E-84 T 06-07-2017 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 GTHT12_RS09605 e81a53790921ea8a9e193b461612921d 788 Gene3D G3DSA:3.40.390.10 331 417 1.0E-20 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 GTHT12_RS14320 246d9b5adbbed98afe0e13a972f68a4f 371 Gene3D G3DSA:3.40.50.1770 202 352 7.4E-31 T 06-07-2017 GTHT12_RS14320 246d9b5adbbed98afe0e13a972f68a4f 371 Gene3D G3DSA:3.40.50.1770 2 171 2.4E-61 T 06-07-2017 GTHT12_RS14320 246d9b5adbbed98afe0e13a972f68a4f 371 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 2 370 5.3E-179 T 06-07-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 GTHT12_RS14320 246d9b5adbbed98afe0e13a972f68a4f 371 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 06-07-2017 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 GTHT12_RS14320 246d9b5adbbed98afe0e13a972f68a4f 371 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 06-07-2017 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 GTHT12_RS14320 246d9b5adbbed98afe0e13a972f68a4f 371 PIRSF PIRSF000183 1 371 3.9E-191 T 06-07-2017 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 GTHT12_RS14320 246d9b5adbbed98afe0e13a972f68a4f 371 SMART SM01003 4 136 3.6E-80 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal GTHT12_RS14320 246d9b5adbbed98afe0e13a972f68a4f 371 SMART SM01002 148 297 1.1E-89 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain GTHT12_RS14320 246d9b5adbbed98afe0e13a972f68a4f 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 352 4.6E-85 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain GTHT12_RS14320 246d9b5adbbed98afe0e13a972f68a4f 371 SUPERFAMILY SSF51735 136 303 9.44E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS14320 246d9b5adbbed98afe0e13a972f68a4f 371 SUPERFAMILY SSF52283 305 360 2.98E-69 T 06-07-2017 GTHT12_RS14320 246d9b5adbbed98afe0e13a972f68a4f 371 SUPERFAMILY SSF52283 2 136 2.98E-69 T 06-07-2017 GTHT12_RS14320 246d9b5adbbed98afe0e13a972f68a4f 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 8.0E-48 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal GTHT12_RS14320 246d9b5adbbed98afe0e13a972f68a4f 371 Gene3D G3DSA:3.50.50.60 172 201 3.8E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS08505 ea0a7a912d10390e0d23583a58a26563 404 PRINTS PR01035 Tetracycline resistance protein signature 135 157 5.9E-18 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS08505 ea0a7a912d10390e0d23583a58a26563 404 PRINTS PR01035 Tetracycline resistance protein signature 163 183 5.9E-18 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS08505 ea0a7a912d10390e0d23583a58a26563 404 PRINTS PR01035 Tetracycline resistance protein signature 20 36 5.9E-18 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS08505 ea0a7a912d10390e0d23583a58a26563 404 PRINTS PR01035 Tetracycline resistance protein signature 338 361 5.9E-18 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS08505 ea0a7a912d10390e0d23583a58a26563 404 SUPERFAMILY SSF103473 7 386 1.26E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS08505 ea0a7a912d10390e0d23583a58a26563 404 ProSitePatterns PS00216 Sugar transport proteins signature 1. 64 80 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 GTHT12_RS08505 ea0a7a912d10390e0d23583a58a26563 404 Gene3D G3DSA:1.20.1250.20 10 188 2.0E-37 T 06-07-2017 GTHT12_RS08505 ea0a7a912d10390e0d23583a58a26563 404 Gene3D G3DSA:1.20.1250.20 214 385 1.3E-22 T 06-07-2017 GTHT12_RS08505 ea0a7a912d10390e0d23583a58a26563 404 Pfam PF07690 Major Facilitator Superfamily 14 261 1.9E-42 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS08710 21fc13e1e5a4d77958bb563d14450ea4 457 PIRSF PIRSF006060 1 457 4.6E-72 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 GTHT12_RS08710 21fc13e1e5a4d77958bb563d14450ea4 457 ProSitePatterns PS00218 Amino acid permeases signature. 41 71 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 GTHT12_RS08710 21fc13e1e5a4d77958bb563d14450ea4 457 Pfam PF00324 Amino acid permease 16 412 1.2E-82 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 GTHT12_RS07530 b0e422b4d1d962a868e6770504a6f8c5 347 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 203 341 1.6E-31 T 06-07-2017 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding GTHT12_RS07530 b0e422b4d1d962a868e6770504a6f8c5 347 Pfam PF03445 Putative nucleotidyltransferase DUF294 37 164 1.9E-32 T 06-07-2017 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 GTHT12_RS15765 db1f5ea36ed0c1343c42a709af22b7a0 259 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 230 252 1.2E-11 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal GTHT12_RS15765 db1f5ea36ed0c1343c42a709af22b7a0 259 SUPERFAMILY SSF52540 5 253 6.07E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS15765 db1f5ea36ed0c1343c42a709af22b7a0 259 Gene3D G3DSA:3.40.50.300 3 252 6.1E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS15765 db1f5ea36ed0c1343c42a709af22b7a0 259 SMART SM00382 30 230 1.8E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS15765 db1f5ea36ed0c1343c42a709af22b7a0 259 Pfam PF00005 ABC transporter 22 182 5.2E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS07305 4e40bb00ace08902c9101f8f9db70e44 104 Gene3D G3DSA:1.10.10.10 11 103 4.7E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS07305 4e40bb00ace08902c9101f8f9db70e44 104 SMART SM00418 21 99 1.5E-30 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS07305 4e40bb00ace08902c9101f8f9db70e44 104 Pfam PF01022 Bacterial regulatory protein, arsR family 28 74 4.8E-16 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS07305 4e40bb00ace08902c9101f8f9db70e44 104 SUPERFAMILY SSF46785 10 102 2.88E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS07305 4e40bb00ace08902c9101f8f9db70e44 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 23 38 6.1E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS07305 4e40bb00ace08902c9101f8f9db70e44 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 6.1E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS07305 4e40bb00ace08902c9101f8f9db70e44 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 6.1E-14 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS06405 3012d7712df2ee56bc5ccf8291b5c797 222 Pfam PF00813 FliP family 25 217 1.2E-84 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 GTHT12_RS06405 3012d7712df2ee56bc5ccf8291b5c797 222 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 150 165 - T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 GTHT12_RS06405 3012d7712df2ee56bc5ccf8291b5c797 222 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 198 210 - T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 GTHT12_RS06405 3012d7712df2ee56bc5ccf8291b5c797 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 150 170 4.4E-68 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 GTHT12_RS06405 3012d7712df2ee56bc5ccf8291b5c797 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 62 81 4.4E-68 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 GTHT12_RS06405 3012d7712df2ee56bc5ccf8291b5c797 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 23 42 4.4E-68 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 GTHT12_RS06405 3012d7712df2ee56bc5ccf8291b5c797 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 171 192 4.4E-68 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 GTHT12_RS06405 3012d7712df2ee56bc5ccf8291b5c797 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 195 220 4.4E-68 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 GTHT12_RS06405 3012d7712df2ee56bc5ccf8291b5c797 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 42 62 4.4E-68 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 GTHT12_RS06405 3012d7712df2ee56bc5ccf8291b5c797 222 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 143 155 3.2E-23 T 06-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 GTHT12_RS06405 3012d7712df2ee56bc5ccf8291b5c797 222 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 93 107 3.2E-23 T 06-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 GTHT12_RS06405 3012d7712df2ee56bc5ccf8291b5c797 222 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 21 30 3.2E-23 T 06-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 GTHT12_RS06405 3012d7712df2ee56bc5ccf8291b5c797 222 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 121 133 3.2E-23 T 06-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 GTHT12_RS06405 3012d7712df2ee56bc5ccf8291b5c797 222 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 211 221 3.2E-23 T 06-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 GTHT12_RS06405 3012d7712df2ee56bc5ccf8291b5c797 222 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 81 93 3.2E-23 T 06-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 GTHT12_RS06405 3012d7712df2ee56bc5ccf8291b5c797 222 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 25 221 1.0E-92 T 06-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 GTHT12_RS16675 ed5c9e05015c8b2b6b88ebcd3a181369 329 SUPERFAMILY SSF53822 60 324 1.45E-86 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS16675 ed5c9e05015c8b2b6b88ebcd3a181369 329 Pfam PF13377 Periplasmic binding protein-like domain 164 323 2.0E-36 T 06-07-2017 GTHT12_RS16675 ed5c9e05015c8b2b6b88ebcd3a181369 329 Gene3D G3DSA:3.40.50.2300 164 324 1.4E-58 T 06-07-2017 GTHT12_RS16675 ed5c9e05015c8b2b6b88ebcd3a181369 329 Gene3D G3DSA:3.40.50.2300 61 163 1.4E-42 T 06-07-2017 GTHT12_RS16675 ed5c9e05015c8b2b6b88ebcd3a181369 329 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 7.9E-7 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS16675 ed5c9e05015c8b2b6b88ebcd3a181369 329 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 7.9E-7 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS16675 ed5c9e05015c8b2b6b88ebcd3a181369 329 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 06-07-2017 GTHT12_RS16675 ed5c9e05015c8b2b6b88ebcd3a181369 329 Gene3D G3DSA:1.10.260.40 2 60 2.1E-26 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS16675 ed5c9e05015c8b2b6b88ebcd3a181369 329 SMART SM00354 1 71 3.0E-39 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS16675 ed5c9e05015c8b2b6b88ebcd3a181369 329 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 4.0E-22 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS16675 ed5c9e05015c8b2b6b88ebcd3a181369 329 SUPERFAMILY SSF47413 1 59 1.22E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS03485 3b945fbdb8255068a3e01494d8578695 196 PIRSF PIRSF037394 1 194 2.0E-64 T 06-07-2017 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted GTHT12_RS03485 3b945fbdb8255068a3e01494d8578695 196 Pfam PF09819 ABC-type cobalt transport system, permease component 12 128 7.1E-38 T 06-07-2017 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted GTHT12_RS06680 a4855e0da34f0a1cee4d5ed4386e4150 429 SUPERFAMILY SSF63411 15 220 1.68E-41 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 GTHT12_RS06680 a4855e0da34f0a1cee4d5ed4386e4150 429 Gene3D G3DSA:3.30.830.10 251 424 4.6E-16 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 GTHT12_RS06680 a4855e0da34f0a1cee4d5ed4386e4150 429 SUPERFAMILY SSF63411 249 425 1.28E-21 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 GTHT12_RS06680 a4855e0da34f0a1cee4d5ed4386e4150 429 Pfam PF05193 Peptidase M16 inactive domain 182 361 4.9E-20 T 06-07-2017 IPR007863 Peptidase M16, C-terminal GTHT12_RS06680 a4855e0da34f0a1cee4d5ed4386e4150 429 Pfam PF00675 Insulinase (Peptidase family M16) 63 174 1.6E-16 T 06-07-2017 IPR011765 Peptidase M16, N-terminal GTHT12_RS06680 a4855e0da34f0a1cee4d5ed4386e4150 429 Gene3D G3DSA:3.30.830.10 16 223 4.7E-41 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 GTHT12_RS16300 c36311168843ef6ec058b707449c936b 213 Gene3D G3DSA:3.30.70.240 138 208 7.9E-14 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain GTHT12_RS16300 c36311168843ef6ec058b707449c936b 213 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 2 202 3.6E-77 T 06-07-2017 IPR015796 Impact family, bacterial/archaeal GTHT12_RS16300 c36311168843ef6ec058b707449c936b 213 SUPERFAMILY SSF54211 3 131 1.67E-44 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS16300 c36311168843ef6ec058b707449c936b 213 SUPERFAMILY SSF54980 135 202 3.81E-13 T 06-07-2017 IPR009022 Elongation factor G, III-V domain GTHT12_RS16300 c36311168843ef6ec058b707449c936b 213 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 06-07-2017 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site GTHT12_RS16300 c36311168843ef6ec058b707449c936b 213 Gene3D G3DSA:3.30.230.30 5 132 6.4E-49 T 06-07-2017 IPR001498 Impact, N-terminal GTHT12_RS16300 c36311168843ef6ec058b707449c936b 213 Pfam PF09186 Domain of unknown function (DUF1949) 140 195 2.2E-20 T 06-07-2017 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal GTHT12_RS16300 c36311168843ef6ec058b707449c936b 213 Pfam PF01205 Uncharacterized protein family UPF0029 20 123 5.7E-31 T 06-07-2017 IPR001498 Impact, N-terminal GTHT12_RS02795 e52bdc97c2865cea7dbcf727bd67d52f 341 SMART SM00387 245 338 2.6E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS02795 e52bdc97c2865cea7dbcf727bd67d52f 341 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 245 336 1.4E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS02795 e52bdc97c2865cea7dbcf727bd67d52f 341 Pfam PF07730 Histidine kinase 142 209 6.4E-19 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 GTHT12_RS02795 e52bdc97c2865cea7dbcf727bd67d52f 341 PIRSF PIRSF037431 1 341 5.6E-130 T 06-07-2017 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 GTHT12_RS02795 e52bdc97c2865cea7dbcf727bd67d52f 341 SUPERFAMILY SSF55874 217 336 1.07E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS02795 e52bdc97c2865cea7dbcf727bd67d52f 341 Gene3D G3DSA:3.30.565.10 214 336 1.4E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS18055 a23129c71bcf427458241193262552c6 311 Gene3D G3DSA:3.40.50.300 2 222 2.2E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18055 a23129c71bcf427458241193262552c6 311 Pfam PF00005 ABC transporter 19 162 7.3E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS18055 a23129c71bcf427458241193262552c6 311 SMART SM00382 28 219 4.0E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS18055 a23129c71bcf427458241193262552c6 311 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS18055 a23129c71bcf427458241193262552c6 311 SUPERFAMILY SSF52540 3 221 1.63E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03725 eb0d7b4d0f4546abf2c1e886d50c4d9d 336 SUPERFAMILY SSF53822 53 306 1.04E-16 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS03725 eb0d7b4d0f4546abf2c1e886d50c4d9d 336 Gene3D G3DSA:3.40.50.2300 43 171 1.2E-53 T 06-07-2017 GTHT12_RS03725 eb0d7b4d0f4546abf2c1e886d50c4d9d 336 Pfam PF04392 ABC transporter substrate binding protein 46 328 8.1E-87 T 06-07-2017 IPR007487 ABC transporter, substrate-binding protein GTHT12_RS03725 eb0d7b4d0f4546abf2c1e886d50c4d9d 336 Gene3D G3DSA:3.40.50.2300 172 303 5.7E-46 T 06-07-2017 GTHT12_RS05380 7cad1c3ab262a98bd1c1a59b6ed8caa5 65 ProDom PD053503 YBXH ORF3 1 57 2.0E-23 T 06-07-2017 GTHT12_RS16665 d883a90e5821b1e7a74d87dcf7045d71 132 SUPERFAMILY SSF102546 1 131 1.7E-47 T 06-07-2017 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 GTHT12_RS16665 d883a90e5821b1e7a74d87dcf7045d71 132 Pfam PF05025 RbsD / FucU transport protein family 1 129 2.4E-50 T 06-07-2017 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 GTHT12_RS16665 d883a90e5821b1e7a74d87dcf7045d71 132 Gene3D G3DSA:3.40.1650.10 1 131 9.7E-36 T 06-07-2017 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 GTHT12_RS16665 d883a90e5821b1e7a74d87dcf7045d71 132 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 131 33.199 T 06-07-2017 IPR023064 D-ribose pyranase GO:0016872 GTHT12_RS11025 8c90b8989d0f4eb11a13242b7347907b 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 320 4.8E-29 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 GTHT12_RS11025 8c90b8989d0f4eb11a13242b7347907b 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 301 3.8E-20 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 GTHT12_RS11025 8c90b8989d0f4eb11a13242b7347907b 327 Pfam PF00005 ABC transporter 27 184 6.5E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS11025 8c90b8989d0f4eb11a13242b7347907b 327 Gene3D G3DSA:3.40.50.300 5 258 2.0E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11025 8c90b8989d0f4eb11a13242b7347907b 327 SMART SM00382 35 242 5.5E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS11025 8c90b8989d0f4eb11a13242b7347907b 327 SUPERFAMILY SSF52540 34 317 2.88E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11025 8c90b8989d0f4eb11a13242b7347907b 327 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS01275 5e709edd8244a66014aef3e0d3689001 381 Gene3D G3DSA:3.40.50.2000 150 185 8.4E-4 T 06-07-2017 GTHT12_RS01275 5e709edd8244a66014aef3e0d3689001 381 Gene3D G3DSA:3.40.50.2000 186 336 1.2E-19 T 06-07-2017 GTHT12_RS01275 5e709edd8244a66014aef3e0d3689001 381 SUPERFAMILY SSF53756 15 349 2.36E-30 T 06-07-2017 GTHT12_RS01275 5e709edd8244a66014aef3e0d3689001 381 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 16 185 3.2E-29 T 06-07-2017 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 GTHT12_RS12785 5480168ca35b9455fe41cea8c26b2470 399 SMART SM00382 179 322 0.001 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS12785 5480168ca35b9455fe41cea8c26b2470 399 SUPERFAMILY SSF52540 44 347 7.11E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12785 5480168ca35b9455fe41cea8c26b2470 399 Gene3D G3DSA:3.40.50.300 158 343 1.0E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12785 5480168ca35b9455fe41cea8c26b2470 399 Gene3D G3DSA:3.30.450.90 39 151 4.5E-35 T 06-07-2017 GTHT12_RS12785 5480168ca35b9455fe41cea8c26b2470 399 Pfam PF00437 Type II/IV secretion system protein 55 318 7.4E-65 T 06-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 GTHT12_RS12785 5480168ca35b9455fe41cea8c26b2470 399 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 247 261 - T 06-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 GTHT12_RS13420 f7beb784066c378240ca98c9407ac28e 380 PIRSF PIRSF005572 1 380 4.3E-128 T 06-07-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 GTHT12_RS13420 f7beb784066c378240ca98c9407ac28e 380 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 06-07-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site GTHT12_RS13420 f7beb784066c378240ca98c9407ac28e 380 Pfam PF00266 Aminotransferase class-V 4 365 2.7E-80 T 06-07-2017 IPR000192 Aminotransferase class V domain GTHT12_RS13420 f7beb784066c378240ca98c9407ac28e 380 Gene3D G3DSA:3.90.1150.10 248 371 7.9E-36 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS13420 f7beb784066c378240ca98c9407ac28e 380 SUPERFAMILY SSF53383 3 376 5.24E-106 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS13420 f7beb784066c378240ca98c9407ac28e 380 Gene3D G3DSA:3.40.640.10 16 247 1.2E-90 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS10360 2909ce1d56822697b91dcedb4104d945 228 SMART SM00448 2 115 1.1E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS10360 2909ce1d56822697b91dcedb4104d945 228 PIRSF PIRSF006171 1 228 7.3E-80 T 06-07-2017 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 GTHT12_RS10360 2909ce1d56822697b91dcedb4104d945 228 Gene3D G3DSA:1.10.10.10 167 208 6.1E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS10360 2909ce1d56822697b91dcedb4104d945 228 Pfam PF09339 IclR helix-turn-helix domain 168 208 4.0E-5 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 GTHT12_RS10360 2909ce1d56822697b91dcedb4104d945 228 SUPERFAMILY SSF52172 1 132 7.26E-36 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS10360 2909ce1d56822697b91dcedb4104d945 228 Gene3D G3DSA:3.40.50.2300 1 123 3.0E-31 T 06-07-2017 GTHT12_RS10360 2909ce1d56822697b91dcedb4104d945 228 Pfam PF00072 Response regulator receiver domain 4 114 6.7E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS15020 5f662832228a3550eb9f768ba616953b 156 SUPERFAMILY SSF118196 1 152 1.44E-45 T 06-07-2017 IPR023370 TsaA-like domain GTHT12_RS15020 5f662832228a3550eb9f768ba616953b 156 Pfam PF01980 Uncharacterised protein family UPF0066 27 131 2.8E-28 T 06-07-2017 IPR023370 TsaA-like domain GTHT12_RS15020 5f662832228a3550eb9f768ba616953b 156 Gene3D G3DSA:2.40.30.70 3 149 2.9E-38 T 06-07-2017 IPR023370 TsaA-like domain GTHT12_RS15020 5f662832228a3550eb9f768ba616953b 156 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 1 131 1.3E-29 T 06-07-2017 IPR023370 TsaA-like domain GTHT12_RS01135 cc21151816edb45f0749d5d2034eebc3 471 ProSitePatterns PS00218 Amino acid permeases signature. 40 71 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 GTHT12_RS01135 cc21151816edb45f0749d5d2034eebc3 471 PIRSF PIRSF006060 1 471 1.2E-85 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 GTHT12_RS01135 cc21151816edb45f0749d5d2034eebc3 471 Pfam PF00324 Amino acid permease 15 456 1.1E-125 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 GTHT12_RS12895 8fa3e5c875e7cf7d4ab7f6b325ed6e44 317 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 32 313 3.6E-83 T 06-07-2017 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 GTHT12_RS12895 8fa3e5c875e7cf7d4ab7f6b325ed6e44 317 SUPERFAMILY SSF161098 36 310 6.41E-37 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS12895 8fa3e5c875e7cf7d4ab7f6b325ed6e44 317 Gene3D G3DSA:1.10.3720.10 36 316 1.6E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS12895 8fa3e5c875e7cf7d4ab7f6b325ed6e44 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 314 1.9E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS06220 8069df9b1c90eac4e407f79ad429820b 90 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 25.66 T 06-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS06220 8069df9b1c90eac4e407f79ad429820b 90 Gene3D G3DSA:3.30.1320.10 2 84 4.9E-37 T 06-07-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS06220 8069df9b1c90eac4e407f79ad429820b 90 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 06-07-2017 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS06220 8069df9b1c90eac4e407f79ad429820b 90 SUPERFAMILY SSF54565 2 87 9.29E-36 T 06-07-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS06220 8069df9b1c90eac4e407f79ad429820b 90 Pfam PF00886 Ribosomal protein S16 9 67 1.8E-26 T 06-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS06220 8069df9b1c90eac4e407f79ad429820b 90 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 3.4E-36 T 06-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS17545 0e291f5ffcd4d48cde2186e685ccdf95 148 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 115 130 3.7E-8 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 GTHT12_RS17545 0e291f5ffcd4d48cde2186e685ccdf95 148 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 5 22 3.7E-8 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 GTHT12_RS17545 0e291f5ffcd4d48cde2186e685ccdf95 148 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 42 58 3.7E-8 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 GTHT12_RS17545 0e291f5ffcd4d48cde2186e685ccdf95 148 SUPERFAMILY SSF52788 1 144 5.49E-39 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily GTHT12_RS17545 0e291f5ffcd4d48cde2186e685ccdf95 148 SMART SM00226 3 143 1.1E-29 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily GTHT12_RS17545 0e291f5ffcd4d48cde2186e685ccdf95 148 Gene3D G3DSA:3.40.50.270 1 147 1.4E-43 T 06-07-2017 GTHT12_RS17545 0e291f5ffcd4d48cde2186e685ccdf95 148 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 139 2.7E-28 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily GTHT12_RS01615 6277eb19a4250cd29bdac479f939eaac 228 PIRSF PIRSF001586 1 223 4.1E-92 T 06-07-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GTHT12_RS01615 6277eb19a4250cd29bdac479f939eaac 228 SUPERFAMILY SSF52317 1 220 1.04E-78 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS01615 6277eb19a4250cd29bdac479f939eaac 228 SMART SM01211 1 220 7.7E-140 T 06-07-2017 GTHT12_RS01615 6277eb19a4250cd29bdac479f939eaac 228 Gene3D G3DSA:3.40.50.880 1 221 1.3E-45 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS01615 6277eb19a4250cd29bdac479f939eaac 228 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 219 1.1E-97 T 06-07-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GTHT12_RS01615 6277eb19a4250cd29bdac479f939eaac 228 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 219 1.2E-45 T 06-07-2017 GTHT12_RS01615 6277eb19a4250cd29bdac479f939eaac 228 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 218 46.325 T 06-07-2017 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 GTHT12_RS01695 b2f5467fe4f2df763a435390a0621fcc 186 SUPERFAMILY SSF102405 1 176 2.9E-61 T 06-07-2017 GTHT12_RS01695 b2f5467fe4f2df763a435390a0621fcc 186 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 176 8.2E-67 T 06-07-2017 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG GTHT12_RS01695 b2f5467fe4f2df763a435390a0621fcc 186 Gene3D G3DSA:3.40.50.450 2 184 6.9E-70 T 06-07-2017 GTHT12_RS01695 b2f5467fe4f2df763a435390a0621fcc 186 Pfam PF03641 Possible lysine decarboxylase 46 175 3.6E-41 T 06-07-2017 IPR031100 LOG family GTHT12_RS01545 de7335ec95496935de280fe7c8a1b173 292 Pfam PF13612 Transposase DDE domain 111 267 1.3E-29 T 06-07-2017 IPR025668 Transposase DDE domain GTHT12_RS05995 e614bdca2d4b55b7e031c1d7d9190b25 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 126 143 5.9E-33 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 GTHT12_RS05995 e614bdca2d4b55b7e031c1d7d9190b25 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 207 216 5.9E-33 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 GTHT12_RS05995 e614bdca2d4b55b7e031c1d7d9190b25 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 272 286 5.9E-33 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 GTHT12_RS05995 e614bdca2d4b55b7e031c1d7d9190b25 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 71 80 5.9E-33 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 GTHT12_RS05995 e614bdca2d4b55b7e031c1d7d9190b25 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 33 55 5.9E-33 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 GTHT12_RS05995 e614bdca2d4b55b7e031c1d7d9190b25 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 248 253 5.9E-33 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 GTHT12_RS05995 e614bdca2d4b55b7e031c1d7d9190b25 308 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 147 287 1.8E-22 T 06-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 GTHT12_RS05995 e614bdca2d4b55b7e031c1d7d9190b25 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 127 138 3.2E-22 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GTHT12_RS05995 e614bdca2d4b55b7e031c1d7d9190b25 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 43 62 3.2E-22 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GTHT12_RS05995 e614bdca2d4b55b7e031c1d7d9190b25 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 244 253 3.2E-22 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GTHT12_RS05995 e614bdca2d4b55b7e031c1d7d9190b25 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 256 279 3.2E-22 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GTHT12_RS05995 e614bdca2d4b55b7e031c1d7d9190b25 308 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 290 4.4E-94 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 GTHT12_RS05995 e614bdca2d4b55b7e031c1d7d9190b25 308 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 293 39.563 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 GTHT12_RS05995 e614bdca2d4b55b7e031c1d7d9190b25 308 Gene3D G3DSA:3.40.50.1370 1 136 3.8E-49 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GTHT12_RS05995 e614bdca2d4b55b7e031c1d7d9190b25 308 SUPERFAMILY SSF53671 1 292 2.88E-93 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GTHT12_RS05995 e614bdca2d4b55b7e031c1d7d9190b25 308 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 139 1.0E-37 T 06-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 GTHT12_RS05995 e614bdca2d4b55b7e031c1d7d9190b25 308 Gene3D G3DSA:3.40.50.1370 137 267 1.5E-46 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GTHT12_RS05995 e614bdca2d4b55b7e031c1d7d9190b25 308 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 43 50 - T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 GTHT12_RS04400 7fa751547b4e87129b35a4ee4aad1528 271 Hamap MF_00361 NAD kinase [nadK]. 8 270 23.985 T 06-07-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 GTHT12_RS04400 7fa751547b4e87129b35a4ee4aad1528 271 Pfam PF01513 ATP-NAD kinase 36 192 7.3E-25 T 06-07-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 GTHT12_RS04400 7fa751547b4e87129b35a4ee4aad1528 271 Gene3D G3DSA:2.60.200.30 132 242 3.7E-30 T 06-07-2017 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 GTHT12_RS04400 7fa751547b4e87129b35a4ee4aad1528 271 Gene3D G3DSA:3.40.50.10330 21 131 4.5E-23 T 06-07-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 GTHT12_RS04400 7fa751547b4e87129b35a4ee4aad1528 271 SUPERFAMILY SSF111331 17 268 9.68E-66 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain GTHT12_RS14090 8bcea92c560df5ca1cabe968c71d514c 259 SUPERFAMILY SSF53850 33 256 1.14E-70 T 06-07-2017 GTHT12_RS14090 8bcea92c560df5ca1cabe968c71d514c 259 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 39 254 1.7E-69 T 06-07-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 GTHT12_RS14090 8bcea92c560df5ca1cabe968c71d514c 259 Gene3D G3DSA:3.40.190.10 217 256 9.0E-21 T 06-07-2017 GTHT12_RS14090 8bcea92c560df5ca1cabe968c71d514c 259 Gene3D G3DSA:3.40.190.10 31 115 9.0E-21 T 06-07-2017 GTHT12_RS14090 8bcea92c560df5ca1cabe968c71d514c 259 Pfam PF13531 Bacterial extracellular solute-binding protein 34 256 2.3E-51 T 06-07-2017 GTHT12_RS14090 8bcea92c560df5ca1cabe968c71d514c 259 PIRSF PIRSF004846 1 259 5.3E-87 T 06-07-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 GTHT12_RS14090 8bcea92c560df5ca1cabe968c71d514c 259 Gene3D G3DSA:3.40.190.10 116 216 3.4E-40 T 06-07-2017 GTHT12_RS16750 e68405d2e5371ae83c8657b0ad987527 238 Gene3D G3DSA:3.10.290.30 45 231 1.5E-60 T 06-07-2017 IPR024047 Protein MM3350-like domain GTHT12_RS16750 e68405d2e5371ae83c8657b0ad987527 238 SUPERFAMILY SSF159941 48 231 4.18E-59 T 06-07-2017 IPR024047 Protein MM3350-like domain GTHT12_RS16750 e68405d2e5371ae83c8657b0ad987527 238 Pfam PF07929 Plasmid pRiA4b ORF-3-like protein 49 228 1.4E-58 T 06-07-2017 IPR012912 Plasmid pRiA4b, Orf3 GTHT12_RS11605 6ac4acccbbf0804c08fc083755319c7a 177 Pfam PF08858 IDEAL domain 138 174 5.2E-16 T 06-07-2017 IPR014957 IDEAL domain GTHT12_RS11605 6ac4acccbbf0804c08fc083755319c7a 177 SMART SM00914 138 174 9.1E-15 T 06-07-2017 IPR014957 IDEAL domain GTHT12_RS11605 6ac4acccbbf0804c08fc083755319c7a 177 PIRSF PIRSF007165 1 177 5.2E-81 T 06-07-2017 IPR011188 Uncharacterised protein family UPF0302 GTHT12_RS11605 6ac4acccbbf0804c08fc083755319c7a 177 Hamap MF_00760 UPF0302 protein . 1 177 33.138 T 06-07-2017 IPR011188 Uncharacterised protein family UPF0302 GTHT12_RS11605 6ac4acccbbf0804c08fc083755319c7a 177 Pfam PF08864 UPF0302 domain 8 112 1.8E-48 T 06-07-2017 IPR014963 Uncharacterised domain UPF0302, N-terminal GTHT12_RS17905 4daa29b996c4d85ac060a595801053cb 204 TIGRFAM TIGR02897 QoxC: cytochrome aa3 quinol oxidase, subunit III 15 203 5.4E-88 T 06-07-2017 IPR014246 Quinol oxidase subunit III GO:0015002|GO:0016021|GO:0042773 GTHT12_RS17905 4daa29b996c4d85ac060a595801053cb 204 Gene3D G3DSA:1.20.120.80 24 201 1.0E-48 T 06-07-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17905 4daa29b996c4d85ac060a595801053cb 204 Pfam PF00510 Cytochrome c oxidase subunit III 26 201 7.1E-14 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17905 4daa29b996c4d85ac060a595801053cb 204 SUPERFAMILY SSF81452 22 201 4.19E-53 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS15280 b279d06574e509607e568115c8d0aa13 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 198 216 6.5E-29 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15280 b279d06574e509607e568115c8d0aa13 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 394 408 6.5E-29 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15280 b279d06574e509607e568115c8d0aa13 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 408 421 6.5E-29 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15280 b279d06574e509607e568115c8d0aa13 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 76 95 6.5E-29 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15280 b279d06574e509607e568115c8d0aa13 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 376 394 6.5E-29 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15280 b279d06574e509607e568115c8d0aa13 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 273 294 6.5E-29 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15280 b279d06574e509607e568115c8d0aa13 449 Gene3D G3DSA:3.40.50.10490 200 417 2.4E-98 T 06-07-2017 GTHT12_RS15280 b279d06574e509607e568115c8d0aa13 449 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 408 425 - T 06-07-2017 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15280 b279d06574e509607e568115c8d0aa13 449 Gene3D G3DSA:3.40.50.10490 68 199 1.2E-27 T 06-07-2017 GTHT12_RS15280 b279d06574e509607e568115c8d0aa13 449 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 202 215 - T 06-07-2017 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15280 b279d06574e509607e568115c8d0aa13 449 Pfam PF00342 Phosphoglucose isomerase 375 426 1.1E-4 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15280 b279d06574e509607e568115c8d0aa13 449 Pfam PF00342 Phosphoglucose isomerase 76 295 1.0E-19 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS15280 b279d06574e509607e568115c8d0aa13 449 SUPERFAMILY SSF53697 4 447 5.24E-148 T 06-07-2017 GTHT12_RS15280 b279d06574e509607e568115c8d0aa13 449 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 1 435 27.358 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 GTHT12_RS10475 e220644d9b63663f0e47e1b26fdf312a 269 Gene3D G3DSA:3.40.50.7700 125 261 6.6E-26 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 GTHT12_RS10475 e220644d9b63663f0e47e1b26fdf312a 269 SMART SM01001 124 269 6.1E-38 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 GTHT12_RS10475 e220644d9b63663f0e47e1b26fdf312a 269 Pfam PF00731 AIR carboxylase 126 261 2.9E-17 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 GTHT12_RS10475 e220644d9b63663f0e47e1b26fdf312a 269 SUPERFAMILY SSF52255 124 261 8.63E-31 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 GTHT12_RS15935 561ada5c659a5c1c83f0349bbf76d552 320 Pfam PF02650 WhiA C-terminal HTH domain 221 305 3.9E-36 T 06-07-2017 IPR023054 Sporulation regulator WhiA, C-terminal GTHT12_RS15935 561ada5c659a5c1c83f0349bbf76d552 320 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 19 103 9.9E-35 T 06-07-2017 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain GTHT12_RS15935 561ada5c659a5c1c83f0349bbf76d552 320 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 308 35.462 T 06-07-2017 IPR003802 Sporulation regulator WhiA GO:0043937 GTHT12_RS15935 561ada5c659a5c1c83f0349bbf76d552 320 Gene3D G3DSA:3.10.28.10 119 202 4.4E-6 T 06-07-2017 IPR027434 Homing endonuclease GO:0004519 GTHT12_RS15935 561ada5c659a5c1c83f0349bbf76d552 320 Pfam PF14527 WhiA LAGLIDADG-like domain 125 218 1.9E-35 T 06-07-2017 GTHT12_RS15935 561ada5c659a5c1c83f0349bbf76d552 320 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 306 7.1E-131 T 06-07-2017 GTHT12_RS15935 561ada5c659a5c1c83f0349bbf76d552 320 SUPERFAMILY SSF55608 119 222 9.07E-17 T 06-07-2017 IPR027434 Homing endonuclease GO:0004519 GTHT12_RS06090 48ab75f4dc2eec8f7dfdfdc60936facb 157 Gene3D G3DSA:3.90.45.10 4 147 3.4E-56 T 06-07-2017 IPR023635 Peptide deformylase GTHT12_RS06090 48ab75f4dc2eec8f7dfdfdc60936facb 157 Pfam PF01327 Polypeptide deformylase 4 146 3.4E-46 T 06-07-2017 IPR023635 Peptide deformylase GTHT12_RS06090 48ab75f4dc2eec8f7dfdfdc60936facb 157 PRINTS PR01576 Peptide deformylase signature 88 99 9.8E-34 T 06-07-2017 IPR023635 Peptide deformylase GTHT12_RS06090 48ab75f4dc2eec8f7dfdfdc60936facb 157 PRINTS PR01576 Peptide deformylase signature 33 62 9.8E-34 T 06-07-2017 IPR023635 Peptide deformylase GTHT12_RS06090 48ab75f4dc2eec8f7dfdfdc60936facb 157 PRINTS PR01576 Peptide deformylase signature 100 118 9.8E-34 T 06-07-2017 IPR023635 Peptide deformylase GTHT12_RS06090 48ab75f4dc2eec8f7dfdfdc60936facb 157 PRINTS PR01576 Peptide deformylase signature 119 148 9.8E-34 T 06-07-2017 IPR023635 Peptide deformylase GTHT12_RS06090 48ab75f4dc2eec8f7dfdfdc60936facb 157 Hamap MF_00163 Peptide deformylase [def]. 2 155 27.877 T 06-07-2017 IPR023635 Peptide deformylase GTHT12_RS06090 48ab75f4dc2eec8f7dfdfdc60936facb 157 SUPERFAMILY SSF56420 3 147 2.88E-54 T 06-07-2017 IPR023635 Peptide deformylase GTHT12_RS06090 48ab75f4dc2eec8f7dfdfdc60936facb 157 PIRSF PIRSF004749 1 151 3.9E-47 T 06-07-2017 IPR023635 Peptide deformylase GTHT12_RS06090 48ab75f4dc2eec8f7dfdfdc60936facb 157 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 147 3.1E-50 T 06-07-2017 IPR023635 Peptide deformylase GTHT12_RS17325 ee7a97ac6e1fc9b4a950be580241395b 145 Pfam PF07977 FabA-like domain 11 133 1.5E-37 T 06-07-2017 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 GTHT12_RS17325 ee7a97ac6e1fc9b4a950be580241395b 145 SUPERFAMILY SSF54637 1 138 1.48E-49 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS17325 ee7a97ac6e1fc9b4a950be580241395b 145 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 138 2.7E-59 T 06-07-2017 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 GTHT12_RS17325 ee7a97ac6e1fc9b4a950be580241395b 145 Gene3D G3DSA:3.10.129.10 1 140 5.7E-59 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS17325 ee7a97ac6e1fc9b4a950be580241395b 145 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 141 35.738 T 06-07-2017 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 GTHT12_RS06920 0b1aeb39006cf4e60a3a3842659534cb 59 SUPERFAMILY SSF140500 3 51 7.06E-14 T 06-07-2017 GTHT12_RS06920 0b1aeb39006cf4e60a3a3842659534cb 59 Pfam PF09388 Spo0E like sporulation regulatory protein 6 47 1.9E-12 T 06-07-2017 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 GTHT12_RS17475 8fa93d00cf604ed291b0243bd2133a24 473 Gene3D G3DSA:2.40.10.170 2 82 7.1E-33 T 06-07-2017 GTHT12_RS17475 8fa93d00cf604ed291b0243bd2133a24 473 SUPERFAMILY SSF50615 2 82 1.36E-29 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GTHT12_RS17475 8fa93d00cf604ed291b0243bd2133a24 473 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 80 4.6E-26 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GTHT12_RS17475 8fa93d00cf604ed291b0243bd2133a24 473 SUPERFAMILY SSF52540 84 354 7.02E-93 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17475 8fa93d00cf604ed291b0243bd2133a24 473 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 469 1.2E-262 T 06-07-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 GTHT12_RS17475 8fa93d00cf604ed291b0243bd2133a24 473 Gene3D G3DSA:3.40.50.300 83 352 4.9E-112 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17475 8fa93d00cf604ed291b0243bd2133a24 473 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 342 351 - T 06-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GTHT12_RS17475 8fa93d00cf604ed291b0243bd2133a24 473 SUPERFAMILY SSF47917 354 469 7.32E-53 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GTHT12_RS17475 8fa93d00cf604ed291b0243bd2133a24 473 SMART SM00382 150 335 7.7E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS17475 8fa93d00cf604ed291b0243bd2133a24 473 Gene3D G3DSA:1.10.1140.10 355 472 2.9E-55 T 06-07-2017 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GTHT12_RS17475 8fa93d00cf604ed291b0243bd2133a24 473 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 469 58.897 T 06-07-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 GTHT12_RS17475 8fa93d00cf604ed291b0243bd2133a24 473 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 138 351 2.6E-69 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 GTHT12_RS12660 c24dbc3fa9ea6632b332231e4f0bde17 410 Pfam PF00375 Sodium:dicarboxylate symporter family 3 397 1.3E-138 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS12660 c24dbc3fa9ea6632b332231e4f0bde17 410 PRINTS PR00173 Glutamate-aspartate symporter signature 188 207 1.2E-54 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS12660 c24dbc3fa9ea6632b332231e4f0bde17 410 PRINTS PR00173 Glutamate-aspartate symporter signature 1 18 1.2E-54 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS12660 c24dbc3fa9ea6632b332231e4f0bde17 410 PRINTS PR00173 Glutamate-aspartate symporter signature 352 372 1.2E-54 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS12660 c24dbc3fa9ea6632b332231e4f0bde17 410 PRINTS PR00173 Glutamate-aspartate symporter signature 325 344 1.2E-54 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS12660 c24dbc3fa9ea6632b332231e4f0bde17 410 PRINTS PR00173 Glutamate-aspartate symporter signature 47 67 1.2E-54 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS12660 c24dbc3fa9ea6632b332231e4f0bde17 410 PRINTS PR00173 Glutamate-aspartate symporter signature 290 316 1.2E-54 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS12660 c24dbc3fa9ea6632b332231e4f0bde17 410 PRINTS PR00173 Glutamate-aspartate symporter signature 77 102 1.2E-54 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS12660 c24dbc3fa9ea6632b332231e4f0bde17 410 SUPERFAMILY SSF118215 3 398 1.14E-127 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS12660 c24dbc3fa9ea6632b332231e4f0bde17 410 Gene3D G3DSA:1.10.3860.10 2 402 8.5E-139 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS06335 e31a0046b5160c05fad60f4acd8ff938 339 PIRSF PIRSF003161 4 339 5.0E-127 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 GTHT12_RS06335 e31a0046b5160c05fad60f4acd8ff938 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 39 65 2.4E-82 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 GTHT12_RS06335 e31a0046b5160c05fad60f4acd8ff938 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 277 303 2.4E-82 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 GTHT12_RS06335 e31a0046b5160c05fad60f4acd8ff938 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 10 26 2.4E-82 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 GTHT12_RS06335 e31a0046b5160c05fad60f4acd8ff938 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 253 273 2.4E-82 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 GTHT12_RS06335 e31a0046b5160c05fad60f4acd8ff938 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 200 225 2.4E-82 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 GTHT12_RS06335 e31a0046b5160c05fad60f4acd8ff938 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 119 142 2.4E-82 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 GTHT12_RS06335 e31a0046b5160c05fad60f4acd8ff938 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 231 251 2.4E-82 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 GTHT12_RS06335 e31a0046b5160c05fad60f4acd8ff938 339 SUPERFAMILY SSF48029 12 104 1.83E-22 T 06-07-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical GTHT12_RS06335 e31a0046b5160c05fad60f4acd8ff938 339 Pfam PF14842 FliG N-terminal domain 10 112 2.4E-37 T 06-07-2017 IPR028263 Flagellar motor switch protein FliG, N-terminal domain GTHT12_RS06335 e31a0046b5160c05fad60f4acd8ff938 339 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 6 339 3.6E-152 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 GTHT12_RS06335 e31a0046b5160c05fad60f4acd8ff938 339 Gene3D G3DSA:1.10.220.30 200 338 4.0E-45 T 06-07-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical GTHT12_RS06335 e31a0046b5160c05fad60f4acd8ff938 339 Gene3D G3DSA:1.10.220.30 78 194 1.2E-34 T 06-07-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical GTHT12_RS06335 e31a0046b5160c05fad60f4acd8ff938 339 Pfam PF14841 FliG middle domain 120 193 4.9E-32 T 06-07-2017 IPR032779 Flagellar motor switch protein FliG, middle domain GTHT12_RS06335 e31a0046b5160c05fad60f4acd8ff938 339 Pfam PF01706 FliG C-terminal domain 223 329 6.9E-44 T 06-07-2017 IPR023087 Flagellar motor switch protein FliG, C-terminal GTHT12_RS06335 e31a0046b5160c05fad60f4acd8ff938 339 SUPERFAMILY SSF48029 119 330 8.63E-71 T 06-07-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical GTHT12_RS06335 e31a0046b5160c05fad60f4acd8ff938 339 Gene3D G3DSA:1.10.220.30 14 75 9.5E-17 T 06-07-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical GTHT12_RS12510 7c1a027c3a5c11efb286b11632509da2 630 Gene3D G3DSA:3.40.50.920 493 623 7.0E-40 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GTHT12_RS12510 7c1a027c3a5c11efb286b11632509da2 630 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 2 624 45.933 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 GTHT12_RS12510 7c1a027c3a5c11efb286b11632509da2 630 Gene3D G3DSA:3.40.50.970 235 295 6.1E-58 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS12510 7c1a027c3a5c11efb286b11632509da2 630 Gene3D G3DSA:3.40.50.970 5 187 6.1E-58 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS12510 7c1a027c3a5c11efb286b11632509da2 630 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 3 278 8.9E-119 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 GTHT12_RS12510 7c1a027c3a5c11efb286b11632509da2 630 Pfam PF02779 Transketolase, pyrimidine binding domain 316 477 8.3E-39 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain GTHT12_RS12510 7c1a027c3a5c11efb286b11632509da2 630 ProSitePatterns PS00801 Transketolase signature 1. 28 47 - T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 GTHT12_RS12510 7c1a027c3a5c11efb286b11632509da2 630 SUPERFAMILY SSF52518 239 378 1.62E-74 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS12510 7c1a027c3a5c11efb286b11632509da2 630 SUPERFAMILY SSF52518 5 193 1.62E-74 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS12510 7c1a027c3a5c11efb286b11632509da2 630 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 4 623 4.8E-300 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 GTHT12_RS12510 7c1a027c3a5c11efb286b11632509da2 630 SUPERFAMILY SSF52518 314 503 2.78E-56 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS12510 7c1a027c3a5c11efb286b11632509da2 630 SMART SM00861 316 481 6.9E-65 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain GTHT12_RS12510 7c1a027c3a5c11efb286b11632509da2 630 SUPERFAMILY SSF52922 489 623 1.57E-35 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GTHT12_RS12510 7c1a027c3a5c11efb286b11632509da2 630 Gene3D G3DSA:3.40.50.970 296 492 1.3E-67 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS12510 7c1a027c3a5c11efb286b11632509da2 630 Pfam PF02780 Transketolase, C-terminal domain 493 615 1.9E-33 T 06-07-2017 IPR033248 Transketolase, C-terminal domain GTHT12_RS12510 7c1a027c3a5c11efb286b11632509da2 630 ProSitePatterns PS00802 Transketolase signature 2. 422 438 - T 06-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 GTHT12_RS12430 cb4b6d09b19f04c2426ab7a8ce8ce761 331 Pfam PF00676 Dehydrogenase E1 component 21 320 7.8E-105 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 GTHT12_RS12430 cb4b6d09b19f04c2426ab7a8ce8ce761 331 Gene3D G3DSA:3.40.50.970 6 330 8.8E-130 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS12430 cb4b6d09b19f04c2426ab7a8ce8ce761 331 SUPERFAMILY SSF52518 8 330 5.59E-105 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS04010 1213ab15f331f8e59708f1e00cbbe41d 287 Gene3D G3DSA:3.40.50.10440 64 153 5.6E-39 T 06-07-2017 GTHT12_RS04010 1213ab15f331f8e59708f1e00cbbe41d 287 Gene3D G3DSA:3.40.50.10440 1 28 5.6E-39 T 06-07-2017 GTHT12_RS04010 1213ab15f331f8e59708f1e00cbbe41d 287 SUPERFAMILY SSF82549 1 283 1.07E-92 T 06-07-2017 GTHT12_RS04010 1213ab15f331f8e59708f1e00cbbe41d 287 Gene3D G3DSA:3.30.1180.10 155 283 2.7E-46 T 06-07-2017 GTHT12_RS04010 1213ab15f331f8e59708f1e00cbbe41d 287 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 282 2.8E-85 T 06-07-2017 IPR003797 DegV GTHT12_RS04010 1213ab15f331f8e59708f1e00cbbe41d 287 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 280 3.3E-95 T 06-07-2017 IPR003797 DegV GTHT12_RS04010 1213ab15f331f8e59708f1e00cbbe41d 287 Gene3D G3DSA:2.20.28.50 29 62 3.4E-21 T 06-07-2017 GTHT12_RS08530 17211844fa482e6d8790a7fd6f933c34 392 Gene3D G3DSA:1.10.540.10 1 122 3.2E-28 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS08530 17211844fa482e6d8790a7fd6f933c34 392 Gene3D G3DSA:1.20.140.10 223 384 6.7E-63 T 06-07-2017 GTHT12_RS08530 17211844fa482e6d8790a7fd6f933c34 392 SUPERFAMILY SSF47203 232 385 1.13E-55 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS08530 17211844fa482e6d8790a7fd6f933c34 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 121 2.2E-23 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS08530 17211844fa482e6d8790a7fd6f933c34 392 SUPERFAMILY SSF56645 3 242 1.57E-65 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 GTHT12_RS08530 17211844fa482e6d8790a7fd6f933c34 392 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 GTHT12_RS08530 17211844fa482e6d8790a7fd6f933c34 392 Gene3D G3DSA:2.40.110.10 124 222 2.2E-34 T 06-07-2017 GTHT12_RS08530 17211844fa482e6d8790a7fd6f933c34 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 210 1.3E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 GTHT12_RS08530 17211844fa482e6d8790a7fd6f933c34 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 381 2.6E-47 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS17335 c5ae655fc8f592b563c7c13ac935ff53 273 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 147 4.1E-30 T 06-07-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G GTHT12_RS17335 c5ae655fc8f592b563c7c13ac935ff53 273 Pfam PF00460 Flagella basal body rod protein 5 35 6.4E-11 T 06-07-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 GTHT12_RS17335 c5ae655fc8f592b563c7c13ac935ff53 273 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 194 270 1.0E-15 T 06-07-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain GTHT12_RS17335 c5ae655fc8f592b563c7c13ac935ff53 273 SUPERFAMILY SSF117143 100 232 3.66E-13 T 06-07-2017 GTHT12_RS02440 84f8e597b8b2fbb3d236544ac21204ab 94 SUPERFAMILY SSF54975 1 89 6.11E-28 T 06-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 GTHT12_RS02440 84f8e597b8b2fbb3d236544ac21204ab 94 Gene3D G3DSA:3.30.70.100 1 88 7.0E-30 T 06-07-2017 GTHT12_RS02440 84f8e597b8b2fbb3d236544ac21204ab 94 Pfam PF00708 Acylphosphatase 1 88 8.3E-27 T 06-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 GTHT12_RS02440 84f8e597b8b2fbb3d236544ac21204ab 94 PRINTS PR00112 Acylphosphatase signature 24 49 6.6E-8 T 06-07-2017 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 GTHT12_RS02440 84f8e597b8b2fbb3d236544ac21204ab 94 PRINTS PR00112 Acylphosphatase signature 3 18 6.6E-8 T 06-07-2017 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 GTHT12_RS02440 84f8e597b8b2fbb3d236544ac21204ab 94 ProSitePatterns PS00151 Acylphosphatase signature 2. 32 48 - T 06-07-2017 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 GTHT12_RS02440 84f8e597b8b2fbb3d236544ac21204ab 94 ProSitePatterns PS00150 Acylphosphatase signature 1. 8 18 - T 06-07-2017 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 GTHT12_RS05690 80f33d68f5e364e7bb76a641a5780459 307 Pfam PF01040 UbiA prenyltransferase family 40 290 1.1E-57 T 06-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 GTHT12_RS05690 80f33d68f5e364e7bb76a641a5780459 307 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 83 105 - T 06-07-2017 IPR030470 UbiA prenyltransferase conserved site GTHT12_RS05690 80f33d68f5e364e7bb76a641a5780459 307 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 23 306 18.001 T 06-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 GTHT12_RS05690 80f33d68f5e364e7bb76a641a5780459 307 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 26 304 1.0E-92 T 06-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 GTHT12_RS07675 9d1009190355ec866bfe3b349d07c072 131 SMART SM00994 94 130 5.9E-5 T 06-07-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 GTHT12_RS16700 421172c83b22fca449df2064e759b68c 355 Gene3D G3DSA:3.20.20.120 125 350 2.5E-77 T 06-07-2017 IPR029065 Enolase C-terminal domain-like GTHT12_RS16700 421172c83b22fca449df2064e759b68c 355 Pfam PF13378 Enolase C-terminal domain-like 144 352 1.2E-52 T 06-07-2017 IPR029065 Enolase C-terminal domain-like GTHT12_RS16700 421172c83b22fca449df2064e759b68c 355 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 8 124 6.3E-20 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain GTHT12_RS16700 421172c83b22fca449df2064e759b68c 355 Gene3D G3DSA:3.30.390.10 1 124 5.0E-39 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS16700 421172c83b22fca449df2064e759b68c 355 SUPERFAMILY SSF54826 1 125 3.11E-31 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS16700 421172c83b22fca449df2064e759b68c 355 SMART SM00922 141 239 2.2E-27 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal GTHT12_RS16700 421172c83b22fca449df2064e759b68c 355 SUPERFAMILY SSF51604 112 352 7.99E-68 T 06-07-2017 IPR029065 Enolase C-terminal domain-like GTHT12_RS12445 45d7fdaea1e3813d7bce61c6cd459f5f 366 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 74 87 - T 06-07-2017 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-70614 GTHT12_RS12445 45d7fdaea1e3813d7bce61c6cd459f5f 366 Gene3D G3DSA:3.40.192.10 1 147 2.9E-73 T 06-07-2017 GTHT12_RS12445 45d7fdaea1e3813d7bce61c6cd459f5f 366 Gene3D G3DSA:3.40.50.720 148 336 2.1E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS12445 45d7fdaea1e3813d7bce61c6cd459f5f 366 SMART SM00839 144 351 3.2E-78 T 06-07-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS12445 45d7fdaea1e3813d7bce61c6cd459f5f 366 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 15 131 2.2E-27 T 06-07-2017 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS12445 45d7fdaea1e3813d7bce61c6cd459f5f 366 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 217 346 1.1E-10 T 06-07-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS12445 45d7fdaea1e3813d7bce61c6cd459f5f 366 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 147 200 1.1E-6 T 06-07-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS12445 45d7fdaea1e3813d7bce61c6cd459f5f 366 SUPERFAMILY SSF53223 4 144 4.8E-50 T 06-07-2017 GTHT12_RS12445 45d7fdaea1e3813d7bce61c6cd459f5f 366 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 132 154 2.3E-23 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS12445 45d7fdaea1e3813d7bce61c6cd459f5f 366 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 286 297 2.3E-23 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS12445 45d7fdaea1e3813d7bce61c6cd459f5f 366 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 176 196 2.3E-23 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS12445 45d7fdaea1e3813d7bce61c6cd459f5f 366 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 66 80 2.3E-23 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 GTHT12_RS12445 45d7fdaea1e3813d7bce61c6cd459f5f 366 PIRSF PIRSF000188 1 353 3.5E-173 T 06-07-2017 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 GTHT12_RS12445 45d7fdaea1e3813d7bce61c6cd459f5f 366 SUPERFAMILY SSF51735 141 348 2.34E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS04195 e0c7f372f3039f933e744ce108290959 227 Gene3D G3DSA:2.60.120.10 7 133 8.6E-33 T 06-07-2017 IPR014710 RmlC-like jelly roll fold GTHT12_RS04195 e0c7f372f3039f933e744ce108290959 227 SMART SM00100 1 119 7.5E-19 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain GTHT12_RS04195 e0c7f372f3039f933e744ce108290959 227 Gene3D G3DSA:1.10.10.10 135 226 5.2E-37 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS04195 e0c7f372f3039f933e744ce108290959 227 Pfam PF13545 Crp-like helix-turn-helix domain 141 212 2.7E-18 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 GTHT12_RS04195 e0c7f372f3039f933e744ce108290959 227 SMART SM00419 158 206 3.3E-15 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 GTHT12_RS04195 e0c7f372f3039f933e744ce108290959 227 SUPERFAMILY SSF46785 137 221 6.62E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS04195 e0c7f372f3039f933e744ce108290959 227 SUPERFAMILY SSF51206 3 133 1.03E-32 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like GTHT12_RS04195 e0c7f372f3039f933e744ce108290959 227 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 180 195 2.9E-7 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 GTHT12_RS04195 e0c7f372f3039f933e744ce108290959 227 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 164 180 2.9E-7 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 GTHT12_RS04195 e0c7f372f3039f933e744ce108290959 227 Pfam PF00027 Cyclic nucleotide-binding domain 20 105 7.1E-20 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain GTHT12_RS00075 93b178f0d8263cccc3602eb96ded1440 454 SUPERFAMILY SSF69189 305 400 1.35E-16 T 06-07-2017 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 GTHT12_RS00075 93b178f0d8263cccc3602eb96ded1440 454 SUPERFAMILY SSF56601 10 313 2.04E-81 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS00075 93b178f0d8263cccc3602eb96ded1440 454 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 28 287 4.3E-94 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 GTHT12_RS00075 93b178f0d8263cccc3602eb96ded1440 454 Gene3D G3DSA:2.60.410.10 316 424 2.6E-23 T 06-07-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 GTHT12_RS00075 93b178f0d8263cccc3602eb96ded1440 454 SMART SM00936 313 424 1.6E-17 T 06-07-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 GTHT12_RS00075 93b178f0d8263cccc3602eb96ded1440 454 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 149 162 9.4E-15 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 GTHT12_RS00075 93b178f0d8263cccc3602eb96ded1440 454 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 65 76 9.4E-15 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 GTHT12_RS00075 93b178f0d8263cccc3602eb96ded1440 454 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 122 139 9.4E-15 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 GTHT12_RS00075 93b178f0d8263cccc3602eb96ded1440 454 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 313 424 2.0E-19 T 06-07-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 GTHT12_RS00075 93b178f0d8263cccc3602eb96ded1440 454 Gene3D G3DSA:3.40.710.10 16 312 5.2E-102 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS15470 ebf90dc28d4b35e405c78d0e62f6a8b5 324 Gene3D G3DSA:3.40.50.720 118 292 1.1E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS15470 ebf90dc28d4b35e405c78d0e62f6a8b5 324 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 321 3.7E-33 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 GTHT12_RS15470 ebf90dc28d4b35e405c78d0e62f6a8b5 324 SUPERFAMILY SSF51735 103 290 6.08E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS15470 ebf90dc28d4b35e405c78d0e62f6a8b5 324 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 228 244 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site GTHT12_RS15470 ebf90dc28d4b35e405c78d0e62f6a8b5 324 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 151 178 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 GTHT12_RS15470 ebf90dc28d4b35e405c78d0e62f6a8b5 324 SUPERFAMILY SSF52283 3 137 3.97E-36 T 06-07-2017 GTHT12_RS15470 ebf90dc28d4b35e405c78d0e62f6a8b5 324 Gene3D G3DSA:3.40.50.720 3 117 3.8E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS15470 ebf90dc28d4b35e405c78d0e62f6a8b5 324 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 289 2.6E-66 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 GTHT12_RS13060 d0fa9e3712d52752436760d6827f84aa 700 Pfam PF01966 HD domain 488 628 3.1E-20 T 06-07-2017 IPR006674 HD domain GTHT12_RS13060 d0fa9e3712d52752436760d6827f84aa 700 SMART SM00471 484 638 4.0E-12 T 06-07-2017 IPR003607 HD/PDEase domain GTHT12_RS13060 d0fa9e3712d52752436760d6827f84aa 700 SUPERFAMILY SSF109604 485 632 3.4E-16 T 06-07-2017 GTHT12_RS13060 d0fa9e3712d52752436760d6827f84aa 700 Pfam PF07697 7TM-HD extracellular 46 260 1.9E-46 T 06-07-2017 IPR011624 Metal-dependent phosphohydrolase, 7TM extracellular domain GTHT12_RS13060 d0fa9e3712d52752436760d6827f84aa 700 Pfam PF07698 7TM receptor with intracellular HD hydrolase 267 463 6.6E-39 T 06-07-2017 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain GTHT12_RS13060 d0fa9e3712d52752436760d6827f84aa 700 TIGRFAM TIGR00277 HDIG: HDIG domain 485 582 5.4E-28 T 06-07-2017 IPR006675 HDIG domain GTHT12_RS13060 d0fa9e3712d52752436760d6827f84aa 700 Gene3D G3DSA:1.10.3210.10 482 668 1.9E-26 T 06-07-2017 IPR006674 HD domain GTHT12_RS05210 017ae18f26eb757a1b1c6be60512ee30 259 Gene3D G3DSA:1.10.150.20 179 247 1.9E-25 T 06-07-2017 GTHT12_RS05210 017ae18f26eb757a1b1c6be60512ee30 259 SUPERFAMILY SSF56672 12 247 6.76E-57 T 06-07-2017 GTHT12_RS05210 017ae18f26eb757a1b1c6be60512ee30 259 Pfam PF11798 IMS family HHH motif 180 210 2.7E-9 T 06-07-2017 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 GTHT12_RS05210 017ae18f26eb757a1b1c6be60512ee30 259 Pfam PF00817 impB/mucB/samB family 16 165 4.5E-26 T 06-07-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 GTHT12_RS05210 017ae18f26eb757a1b1c6be60512ee30 259 Gene3D G3DSA:3.30.70.270 80 173 3.7E-17 T 06-07-2017 GTHT12_RS03885 c1c93af3e05f6db83cb4dc5520e9a2c1 450 Pfam PF01554 MatE 16 175 6.3E-32 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 GTHT12_RS03885 c1c93af3e05f6db83cb4dc5520e9a2c1 450 Pfam PF01554 MatE 241 402 1.6E-33 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 GTHT12_RS03885 c1c93af3e05f6db83cb4dc5520e9a2c1 450 TIGRFAM TIGR00797 matE: MATE efflux family protein 16 415 1.1E-66 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 GTHT12_RS03885 c1c93af3e05f6db83cb4dc5520e9a2c1 450 PIRSF PIRSF006603 6 449 2.2E-83 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 GTHT12_RS10995 537e666223363c5ae4ffcbe80bfff961 234 Pfam PF04519 Polymer-forming cytoskeletal 61 133 1.8E-6 T 06-07-2017 IPR007607 Protein of unknown function DUF583 GTHT12_RS10995 537e666223363c5ae4ffcbe80bfff961 234 Pfam PF04519 Polymer-forming cytoskeletal 5 85 8.2E-8 T 06-07-2017 IPR007607 Protein of unknown function DUF583 GTHT12_RS07110 13079fbfa05440eed47b37530cb53f6c 301 Pfam PF04227 Indigoidine synthase A like protein 10 298 1.1E-136 T 06-07-2017 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 GTHT12_RS07110 13079fbfa05440eed47b37530cb53f6c 301 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 9 301 44.059 T 06-07-2017 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 GTHT12_RS07110 13079fbfa05440eed47b37530cb53f6c 301 SUPERFAMILY SSF110581 2 300 4.97E-122 T 06-07-2017 GTHT12_RS10960 1a167991104bb93baac631b3734c1946 75 SUPERFAMILY SSF64307 4 75 6.93E-27 T 06-07-2017 IPR001455 TusA-like domain GTHT12_RS10960 1a167991104bb93baac631b3734c1946 75 Gene3D G3DSA:3.30.110.40 1 75 1.2E-32 T 06-07-2017 IPR001455 TusA-like domain GTHT12_RS10960 1a167991104bb93baac631b3734c1946 75 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 7 31 - T 06-07-2017 IPR001455 TusA-like domain GTHT12_RS10960 1a167991104bb93baac631b3734c1946 75 Pfam PF01206 Sulfurtransferase TusA 5 74 6.6E-26 T 06-07-2017 IPR001455 TusA-like domain GTHT12_RS06070 ec254528880245cf2894133c26a56026 205 Hamap MF_00328 Guanylate kinase [gmk]. 4 188 37.58 T 06-07-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 GTHT12_RS06070 ec254528880245cf2894133c26a56026 205 Gene3D G3DSA:3.30.63.10 36 88 5.2E-29 T 06-07-2017 GTHT12_RS06070 ec254528880245cf2894133c26a56026 205 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 6 185 2.6E-73 T 06-07-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 GTHT12_RS06070 ec254528880245cf2894133c26a56026 205 Gene3D G3DSA:3.40.50.300 3 28 1.1E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06070 ec254528880245cf2894133c26a56026 205 Gene3D G3DSA:3.40.50.300 89 203 1.1E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06070 ec254528880245cf2894133c26a56026 205 SMART SM00072 5 188 3.0E-78 T 06-07-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit GTHT12_RS06070 ec254528880245cf2894133c26a56026 205 Pfam PF00625 Guanylate kinase 8 186 5.9E-52 T 06-07-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit GTHT12_RS06070 ec254528880245cf2894133c26a56026 205 SUPERFAMILY SSF52540 4 192 1.8E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06070 ec254528880245cf2894133c26a56026 205 ProSitePatterns PS00856 Guanylate kinase-like signature. 41 58 - T 06-07-2017 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 GTHT12_RS10385 61a724ff5c43a8e7a4d6d7af088fe4d9 385 Gene3D G3DSA:1.10.1040.10 203 384 2.1E-43 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 GTHT12_RS10385 61a724ff5c43a8e7a4d6d7af088fe4d9 385 Hamap MF_00196 Mannitol-1-phosphate 5-dehydrogenase [mtlD]. 1 378 39.985 T 06-07-2017 IPR023028 Mannitol-1-phosphate 5-dehydrogenase GO:0008926|GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 GTHT12_RS10385 61a724ff5c43a8e7a4d6d7af088fe4d9 385 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 151 365 4.0E-51 T 06-07-2017 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 GTHT12_RS10385 61a724ff5c43a8e7a4d6d7af088fe4d9 385 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 1 124 6.7E-28 T 06-07-2017 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 GTHT12_RS10385 61a724ff5c43a8e7a4d6d7af088fe4d9 385 SUPERFAMILY SSF48179 203 383 7.48E-42 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GTHT12_RS10385 61a724ff5c43a8e7a4d6d7af088fe4d9 385 PRINTS PR00084 Mannitol dehydrogenase signature 115 128 1.1E-18 T 06-07-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 GTHT12_RS10385 61a724ff5c43a8e7a4d6d7af088fe4d9 385 PRINTS PR00084 Mannitol dehydrogenase signature 169 184 1.1E-18 T 06-07-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 GTHT12_RS10385 61a724ff5c43a8e7a4d6d7af088fe4d9 385 PRINTS PR00084 Mannitol dehydrogenase signature 3 13 1.1E-18 T 06-07-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 GTHT12_RS10385 61a724ff5c43a8e7a4d6d7af088fe4d9 385 PRINTS PR00084 Mannitol dehydrogenase signature 151 164 1.1E-18 T 06-07-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 GTHT12_RS10385 61a724ff5c43a8e7a4d6d7af088fe4d9 385 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 151 163 - T 06-07-2017 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 GTHT12_RS10385 61a724ff5c43a8e7a4d6d7af088fe4d9 385 SUPERFAMILY SSF51735 1 201 2.45E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS10385 61a724ff5c43a8e7a4d6d7af088fe4d9 385 Gene3D G3DSA:3.40.50.720 1 200 6.1E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS00815 7231396f28a2eae6c0dcd7e3c3404bfa 265 Pfam PF02361 Cobalt transport protein 15 236 1.2E-58 T 06-07-2017 IPR003339 ABC/ECF transporter, transmembrane component GTHT12_RS00815 7231396f28a2eae6c0dcd7e3c3404bfa 265 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 2 265 37.135 T 06-07-2017 IPR024919 ECF transporter transmembrane protein EcfT GO:0005215|GO:0006810|GO:0016021 GTHT12_RS01010 86dfe896559adee705b9154a68efe8be 293 SUPERFAMILY SSF161098 76 270 1.31E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS01010 86dfe896559adee705b9154a68efe8be 293 Gene3D G3DSA:1.10.3720.10 77 282 5.2E-10 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS01010 86dfe896559adee705b9154a68efe8be 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 251 5.7E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS11970 02750e419a9c845842e7d022b7bff8f6 491 Pfam PF01955 Adenosylcobinamide amidohydrolase 287 476 2.5E-55 T 06-07-2017 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ GTHT12_RS11970 02750e419a9c845842e7d022b7bff8f6 491 SUPERFAMILY SSF52540 3 230 9.22E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11970 02750e419a9c845842e7d022b7bff8f6 491 Gene3D G3DSA:3.40.50.300 3 230 7.4E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11970 02750e419a9c845842e7d022b7bff8f6 491 SMART SM00382 28 217 3.2E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS11970 02750e419a9c845842e7d022b7bff8f6 491 Pfam PF00005 ABC transporter 19 169 1.6E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS01605 d195b261eb7a228ad947ed1167e09319 243 Gene3D G3DSA:3.30.200.20 8 95 1.5E-38 T 06-07-2017 GTHT12_RS01605 d195b261eb7a228ad947ed1167e09319 243 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 6 237 33.374 T 06-07-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GTHT12_RS01605 d195b261eb7a228ad947ed1167e09319 243 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 5 237 2.8E-78 T 06-07-2017 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 GTHT12_RS01605 d195b261eb7a228ad947ed1167e09319 243 ProSitePatterns PS01058 SAICAR synthetase signature 2. 175 183 - T 06-07-2017 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GTHT12_RS01605 d195b261eb7a228ad947ed1167e09319 243 Gene3D G3DSA:3.30.470.20 96 222 6.8E-53 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 GTHT12_RS01605 d195b261eb7a228ad947ed1167e09319 243 Pfam PF01259 SAICAR synthetase 8 231 4.8E-65 T 06-07-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GTHT12_RS01605 d195b261eb7a228ad947ed1167e09319 243 ProSitePatterns PS01057 SAICAR synthetase signature 1. 88 102 - T 06-07-2017 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GTHT12_RS01605 d195b261eb7a228ad947ed1167e09319 243 SUPERFAMILY SSF56104 5 238 1.28E-81 T 06-07-2017 GTHT12_RS11690 75d0592957acdb029616ab0e906f8500 234 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 1 233 36.521 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 GTHT12_RS11690 75d0592957acdb029616ab0e906f8500 234 Gene3D G3DSA:3.40.50.150 7 229 2.4E-56 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS11690 75d0592957acdb029616ab0e906f8500 234 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 141 155 - T 06-07-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 GTHT12_RS11690 75d0592957acdb029616ab0e906f8500 234 TIGRFAM TIGR02752 MenG_heptapren: demethylmenaquinone methyltransferase 3 233 2.0E-140 T 06-07-2017 IPR014122 Demethylmenaquinone methyltransferase GO:0008168|GO:0009234 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 GTHT12_RS11690 75d0592957acdb029616ab0e906f8500 234 SUPERFAMILY SSF53335 4 229 2.61E-53 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS11690 75d0592957acdb029616ab0e906f8500 234 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 20 35 - T 06-07-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 GTHT12_RS11690 75d0592957acdb029616ab0e906f8500 234 Pfam PF01209 ubiE/COQ5 methyltransferase family 2 233 1.3E-98 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 GTHT12_RS11690 75d0592957acdb029616ab0e906f8500 234 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 9 233 8.9E-83 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 GTHT12_RS02520 57038fbe87da76349f90b1c2a021db5c 263 TIGRFAM TIGR02884 spore_pdaA: delta-lactam-biosynthetic de-N-acetylase 27 250 3.6E-117 T 06-07-2017 IPR014235 Delta-lactam-biosynthetic de-N-acetylase GTHT12_RS02520 57038fbe87da76349f90b1c2a021db5c 263 Gene3D G3DSA:3.20.20.370 35 252 1.2E-71 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 GTHT12_RS02520 57038fbe87da76349f90b1c2a021db5c 263 Pfam PF01522 Polysaccharide deacetylase 59 180 2.3E-36 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 GTHT12_RS02520 57038fbe87da76349f90b1c2a021db5c 263 SUPERFAMILY SSF88713 51 251 8.09E-72 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 GTHT12_RS16125 70f12754d7de66430a0faa7097a81ffd 182 Gene3D G3DSA:3.30.160.100 3 94 6.0E-36 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 GTHT12_RS16125 70f12754d7de66430a0faa7097a81ffd 182 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 123 178 4.3E-30 T 06-07-2017 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal GTHT12_RS16125 70f12754d7de66430a0faa7097a81ffd 182 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 101 6.0E-35 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 GTHT12_RS16125 70f12754d7de66430a0faa7097a81ffd 182 SUPERFAMILY SSF69754 3 103 1.29E-34 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 GTHT12_RS16125 70f12754d7de66430a0faa7097a81ffd 182 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 95 5.7E-32 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 GTHT12_RS07550 848f236bfdf509bac120cfcfa695410e 333 Pfam PF01032 FecCD transport family 18 328 4.3E-94 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 GTHT12_RS07550 848f236bfdf509bac120cfcfa695410e 333 SUPERFAMILY SSF81345 5 328 6.41E-81 T 06-07-2017 IPR029022 ABC transporter, BtuC-like GTHT12_RS07550 848f236bfdf509bac120cfcfa695410e 333 Gene3D G3DSA:1.10.3470.10 5 329 9.4E-100 T 06-07-2017 IPR029022 ABC transporter, BtuC-like GTHT12_RS11055 67ee55d907bfd921cd9f3512954d04e9 486 PIRSF PIRSF012702 1 486 3.0E-156 T 06-07-2017 IPR009197 Microcystin LR degradation protein MlrC GTHT12_RS11055 67ee55d907bfd921cd9f3512954d04e9 486 Pfam PF07364 Metallopeptidase family M81 2 288 5.0E-97 T 06-07-2017 IPR015995 Microcystin LR degradation protein MlrC, N-terminal GTHT12_RS11055 67ee55d907bfd921cd9f3512954d04e9 486 Pfam PF07171 MlrC C-terminus 299 475 8.0E-55 T 06-07-2017 IPR010799 Microcystin LR degradation protein MlrC, C-terminal GTHT12_RS10650 85d8196fd114a3bdd8f68dbab3009560 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 265 6.0E-59 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 GTHT12_RS10650 85d8196fd114a3bdd8f68dbab3009560 266 SUPERFAMILY SSF52096 7 265 4.06E-72 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS10650 85d8196fd114a3bdd8f68dbab3009560 266 Gene3D G3DSA:3.90.226.10 9 206 4.2E-61 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS10650 85d8196fd114a3bdd8f68dbab3009560 266 Gene3D G3DSA:1.10.12.10 209 265 8.8E-18 T 06-07-2017 IPR014748 Crontonase, C-terminal GTHT12_RS10650 85d8196fd114a3bdd8f68dbab3009560 266 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 GTHT12_RS15720 10271aabaabaffc6e38dc0ea8b7e7314 633 Gene3D G3DSA:2.40.33.10 346 437 2.7E-8 T 06-07-2017 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GTHT12_RS15720 10271aabaabaffc6e38dc0ea8b7e7314 633 SUPERFAMILY SSF51621 130 222 4.19E-60 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GTHT12_RS15720 10271aabaabaffc6e38dc0ea8b7e7314 633 SUPERFAMILY SSF51621 439 606 4.19E-60 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GTHT12_RS15720 10271aabaabaffc6e38dc0ea8b7e7314 633 Gene3D G3DSA:3.20.20.60 143 221 8.1E-62 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GTHT12_RS15720 10271aabaabaffc6e38dc0ea8b7e7314 633 Gene3D G3DSA:3.20.20.60 440 604 8.1E-62 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GTHT12_RS15720 10271aabaabaffc6e38dc0ea8b7e7314 633 SUPERFAMILY SSF50800 344 437 2.44E-9 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain GTHT12_RS15720 10271aabaabaffc6e38dc0ea8b7e7314 633 Pfam PF00224 Pyruvate kinase, barrel domain 345 606 3.5E-37 T 06-07-2017 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GTHT12_RS15720 10271aabaabaffc6e38dc0ea8b7e7314 633 Pfam PF00224 Pyruvate kinase, barrel domain 143 235 1.9E-7 T 06-07-2017 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 GTHT12_RS07555 a06692e857e41a8018277ad202b9afc8 350 Gene3D G3DSA:1.10.3470.10 19 349 2.0E-100 T 06-07-2017 IPR029022 ABC transporter, BtuC-like GTHT12_RS07555 a06692e857e41a8018277ad202b9afc8 350 SUPERFAMILY SSF81345 14 346 1.57E-79 T 06-07-2017 IPR029022 ABC transporter, BtuC-like GTHT12_RS07555 a06692e857e41a8018277ad202b9afc8 350 Pfam PF01032 FecCD transport family 33 346 1.8E-94 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 GTHT12_RS11890 85376d1bcd8565f103652e4ab478208a 348 Pfam PF14493 Helix-turn-helix domain 251 339 5.0E-25 T 06-07-2017 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 GTHT12_RS11890 85376d1bcd8565f103652e4ab478208a 348 Gene3D G3DSA:1.10.10.10 247 286 5.0E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS11890 85376d1bcd8565f103652e4ab478208a 348 PIRSF PIRSF021350 5 346 1.1E-84 T 06-07-2017 IPR008308 Uncharacterised conserved protein UCP021350 GTHT12_RS10085 8c0b710f18af08fd3b6561157724ba07 155 Pfam PF00005 ABC transporter 35 84 5.4E-9 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS10085 8c0b710f18af08fd3b6561157724ba07 155 Gene3D G3DSA:3.40.50.300 28 150 6.7E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10085 8c0b710f18af08fd3b6561157724ba07 155 SUPERFAMILY SSF52540 26 143 1.62E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03630 787d4afb653c3d26acbf24d0c3cff795 174 Pfam PF17099 Tryptophan transporter TrpP 2 166 8.5E-55 T 06-07-2017 IPR031360 Tryptophan transporter TrpP GTHT12_RS03630 787d4afb653c3d26acbf24d0c3cff795 174 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 163 2.0E-62 T 06-07-2017 GTHT12_RS13625 59e8c001bbba2c76c712cc879a3a6f48 96 TIGRFAM TIGR00062 L27: ribosomal protein bL27 9 90 1.3E-39 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS13625 59e8c001bbba2c76c712cc879a3a6f48 96 Gene3D G3DSA:2.40.50.100 28 92 1.4E-30 T 06-07-2017 GTHT12_RS13625 59e8c001bbba2c76c712cc879a3a6f48 96 PRINTS PR00063 Ribosomal protein L27 signature 37 61 3.7E-38 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS13625 59e8c001bbba2c76c712cc879a3a6f48 96 PRINTS PR00063 Ribosomal protein L27 signature 62 86 3.7E-38 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS13625 59e8c001bbba2c76c712cc879a3a6f48 96 PRINTS PR00063 Ribosomal protein L27 signature 12 36 3.7E-38 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS13625 59e8c001bbba2c76c712cc879a3a6f48 96 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 36 77 1.0E-17 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS13625 59e8c001bbba2c76c712cc879a3a6f48 96 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 9 92 26.763 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS13625 59e8c001bbba2c76c712cc879a3a6f48 96 Pfam PF01016 Ribosomal L27 protein 10 89 2.8E-34 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS13625 59e8c001bbba2c76c712cc879a3a6f48 96 ProSitePatterns PS00831 Ribosomal protein L27 signature. 42 56 - T 06-07-2017 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS13625 59e8c001bbba2c76c712cc879a3a6f48 96 SUPERFAMILY SSF110324 10 91 8.37E-32 T 06-07-2017 GTHT12_RS07960 600efa7ffdb5bdee476d72990c0b9a5d 549 SUPERFAMILY SSF81442 12 543 2.62E-116 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS07960 600efa7ffdb5bdee476d72990c0b9a5d 549 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 15 468 7.4E-89 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS07960 600efa7ffdb5bdee476d72990c0b9a5d 549 Gene3D G3DSA:1.20.210.10 12 488 1.5E-78 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS07960 600efa7ffdb5bdee476d72990c0b9a5d 549 PRINTS PR01165 Cytochrome c oxidase subunit I signature 119 131 4.7E-14 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS07960 600efa7ffdb5bdee476d72990c0b9a5d 549 PRINTS PR01165 Cytochrome c oxidase subunit I signature 51 74 4.7E-14 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS07960 600efa7ffdb5bdee476d72990c0b9a5d 549 PRINTS PR01165 Cytochrome c oxidase subunit I signature 288 309 4.7E-14 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS07960 600efa7ffdb5bdee476d72990c0b9a5d 549 PRINTS PR01165 Cytochrome c oxidase subunit I signature 217 238 4.7E-14 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS07960 600efa7ffdb5bdee476d72990c0b9a5d 549 PRINTS PR01165 Cytochrome c oxidase subunit I signature 419 440 4.7E-14 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS07960 600efa7ffdb5bdee476d72990c0b9a5d 549 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 219 273 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS11220 3f6ecc3200b77cf9da07a6397ffb33d4 478 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 434 2.6E-62 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 GTHT12_RS11220 3f6ecc3200b77cf9da07a6397ffb33d4 478 Pfam PF00474 Sodium:solute symporter family 33 434 1.3E-65 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 GTHT12_RS09880 3a11f8d28af27a903584b004ed4b3f02 316 Gene3D G3DSA:1.10.3720.10 77 307 1.4E-48 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS09880 3a11f8d28af27a903584b004ed4b3f02 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 303 3.0E-7 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS09880 3a11f8d28af27a903584b004ed4b3f02 316 SUPERFAMILY SSF161098 71 300 3.53E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS08720 3acb5418ed356ae7c3b6429a15290a85 481 PIRSF PIRSF026631 1 481 2.2E-108 T 06-07-2017 IPR014529 Uncharacterised conserved protein UCP026631 GTHT12_RS08720 3acb5418ed356ae7c3b6429a15290a85 481 Pfam PF03703 Bacterial PH domain 253 327 8.4E-13 T 06-07-2017 IPR005182 Domain of unknown function DUF304 GTHT12_RS08720 3acb5418ed356ae7c3b6429a15290a85 481 Pfam PF03703 Bacterial PH domain 62 141 7.0E-17 T 06-07-2017 IPR005182 Domain of unknown function DUF304 GTHT12_RS08720 3acb5418ed356ae7c3b6429a15290a85 481 Pfam PF03703 Bacterial PH domain 395 472 5.1E-12 T 06-07-2017 IPR005182 Domain of unknown function DUF304 GTHT12_RS13905 161bf126bb2d28944c6dab6cc835aacf 169 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 146 9.9E-37 T 06-07-2017 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 GTHT12_RS13905 161bf126bb2d28944c6dab6cc835aacf 169 SUPERFAMILY SSF56300 1 159 3.49E-47 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like GTHT12_RS13905 161bf126bb2d28944c6dab6cc835aacf 169 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 147 4.1E-36 T 06-07-2017 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 GTHT12_RS13905 161bf126bb2d28944c6dab6cc835aacf 169 Gene3D G3DSA:3.60.21.10 1 156 1.1E-41 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like GTHT12_RS07120 b84eea4cddfd238fb4cd4a06f1b5a7c7 179 SUPERFAMILY SSF51182 24 163 2.0E-28 T 06-07-2017 IPR011051 RmlC-like cupin domain GTHT12_RS07120 b84eea4cddfd238fb4cd4a06f1b5a7c7 179 Gene3D G3DSA:2.60.120.10 59 177 2.7E-45 T 06-07-2017 IPR014710 RmlC-like jelly roll fold GTHT12_RS07120 b84eea4cddfd238fb4cd4a06f1b5a7c7 179 Pfam PF07883 Cupin domain 83 158 5.1E-15 T 06-07-2017 IPR013096 Cupin 2, conserved barrel GTHT12_RS10275 299398672439d07ed0189579bb9dce45 311 SUPERFAMILY SSF160964 33 95 2.09E-8 T 06-07-2017 GTHT12_RS10275 299398672439d07ed0189579bb9dce45 311 Gene3D G3DSA:1.20.58.370 32 62 3.5E-4 T 06-07-2017 GTHT12_RS10275 299398672439d07ed0189579bb9dce45 311 SUPERFAMILY SSF161098 76 301 2.22E-58 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS10275 299398672439d07ed0189579bb9dce45 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 303 1.1E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS10275 299398672439d07ed0189579bb9dce45 311 Gene3D G3DSA:1.10.3720.10 82 308 4.4E-58 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS17970 cd971c03baeb9c8d1a80cba366344f29 156 SUPERFAMILY SSF46785 23 145 3.96E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS17970 cd971c03baeb9c8d1a80cba366344f29 156 SMART SM00347 32 132 3.2E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS17970 cd971c03baeb9c8d1a80cba366344f29 156 Pfam PF01047 MarR family 52 96 1.4E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS17970 cd971c03baeb9c8d1a80cba366344f29 156 Gene3D G3DSA:1.10.10.10 10 145 1.3E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS17710 5ba0a4b28f2e54d69346c62a669a57fa 681 SUPERFAMILY SSF56601 219 241 1.31E-121 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS17710 5ba0a4b28f2e54d69346c62a669a57fa 681 SUPERFAMILY SSF56601 270 661 1.31E-121 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS17710 5ba0a4b28f2e54d69346c62a669a57fa 681 Pfam PF00905 Penicillin binding protein transpeptidase domain 327 571 1.3E-30 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 GTHT12_RS17710 5ba0a4b28f2e54d69346c62a669a57fa 681 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 73 607 4.6E-187 T 06-07-2017 GTHT12_RS17710 5ba0a4b28f2e54d69346c62a669a57fa 681 Pfam PF00912 Transglycosylase 64 237 4.9E-67 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 GTHT12_RS17710 5ba0a4b28f2e54d69346c62a669a57fa 681 Gene3D G3DSA:3.40.710.10 240 660 1.8E-121 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS17710 5ba0a4b28f2e54d69346c62a669a57fa 681 Gene3D G3DSA:1.10.3810.10 67 239 2.7E-77 T 06-07-2017 GTHT12_RS17710 5ba0a4b28f2e54d69346c62a669a57fa 681 SUPERFAMILY SSF53955 50 261 7.59E-79 T 06-07-2017 IPR023346 Lysozyme-like domain GTHT12_RS08850 b7f7750ee5746bc744ba0812360fe154 141 SUPERFAMILY SSF55811 6 132 5.01E-23 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 GTHT12_RS08850 b7f7750ee5746bc744ba0812360fe154 141 Gene3D G3DSA:3.90.79.10 1 137 9.0E-23 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 GTHT12_RS08850 b7f7750ee5746bc744ba0812360fe154 141 PRINTS PR00502 NUDIX hydrolase family signature 35 49 1.1E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 GTHT12_RS08850 b7f7750ee5746bc744ba0812360fe154 141 PRINTS PR00502 NUDIX hydrolase family signature 49 64 1.1E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 GTHT12_RS08850 b7f7750ee5746bc744ba0812360fe154 141 Pfam PF00293 NUDIX domain 9 131 2.2E-16 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 GTHT12_RS08850 b7f7750ee5746bc744ba0812360fe154 141 ProSitePatterns PS00893 Nudix box signature. 40 61 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 GTHT12_RS01715 b8ec531eacc30382574a23c42a580298 96 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 96 1.9E-33 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 GTHT12_RS01715 b8ec531eacc30382574a23c42a580298 96 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 27.374 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 GTHT12_RS01715 b8ec531eacc30382574a23c42a580298 96 SUPERFAMILY SSF141000 3 94 5.62E-34 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 GTHT12_RS01715 b8ec531eacc30382574a23c42a580298 96 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 21 91 1.5E-24 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 GTHT12_RS18295 f58f1676efeeb9e81f3ab402546607ab 385 SUPERFAMILY SSF52540 111 348 2.92E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18295 f58f1676efeeb9e81f3ab402546607ab 385 Gene3D G3DSA:3.40.50.300 118 340 6.9E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18295 f58f1676efeeb9e81f3ab402546607ab 385 Pfam PF01580 FtsK/SpoIIIE family 121 300 1.0E-18 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 GTHT12_RS17825 5a5635295e1c644701c31f9469d78677 256 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 251 4.9E-35 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS17825 5a5635295e1c644701c31f9469d78677 256 Gene3D G3DSA:1.10.10.10 111 153 1.2E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS17825 5a5635295e1c644701c31f9469d78677 256 SUPERFAMILY SSF88659 170 252 3.92E-17 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS17825 5a5635295e1c644701c31f9469d78677 256 Pfam PF04545 Sigma-70, region 4 200 248 4.7E-13 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS17825 5a5635295e1c644701c31f9469d78677 256 PRINTS PR00046 Major sigma-70 factor signature 236 247 1.6E-5 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS17825 5a5635295e1c644701c31f9469d78677 256 PRINTS PR00046 Major sigma-70 factor signature 57 70 1.6E-5 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS17825 5a5635295e1c644701c31f9469d78677 256 PRINTS PR00046 Major sigma-70 factor signature 221 236 1.6E-5 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS17825 5a5635295e1c644701c31f9469d78677 256 PRINTS PR00046 Major sigma-70 factor signature 204 216 1.6E-5 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS17825 5a5635295e1c644701c31f9469d78677 256 Gene3D G3DSA:1.10.10.10 196 251 2.7E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS17825 5a5635295e1c644701c31f9469d78677 256 Pfam PF04539 Sigma-70 region 3 112 187 3.6E-12 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS17825 5a5635295e1c644701c31f9469d78677 256 Gene3D G3DSA:1.10.1740.10 8 110 2.5E-9 T 06-07-2017 GTHT12_RS17825 5a5635295e1c644701c31f9469d78677 256 Pfam PF04542 Sigma-70 region 2 34 102 6.1E-13 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS17825 5a5635295e1c644701c31f9469d78677 256 SUPERFAMILY SSF88946 9 102 1.44E-15 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS17825 5a5635295e1c644701c31f9469d78677 256 SUPERFAMILY SSF88659 106 184 1.13E-16 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS14805 5d0502d273e44bf91aac87d5eb83a102 272 SMART SM00382 31 229 4.5E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS14805 5d0502d273e44bf91aac87d5eb83a102 272 Pfam PF00005 ABC transporter 23 178 3.7E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS14805 5d0502d273e44bf91aac87d5eb83a102 272 Gene3D G3DSA:3.40.50.300 5 233 1.3E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS14805 5d0502d273e44bf91aac87d5eb83a102 272 SUPERFAMILY SSF52540 4 234 1.82E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS14805 5d0502d273e44bf91aac87d5eb83a102 272 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS14470 d31c982c56c7eee9c97107ca6a4c08e8 389 ProSitePatterns PS01007 Transposases, Mutator family, signature. 221 245 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS14470 d31c982c56c7eee9c97107ca6a4c08e8 389 Pfam PF00872 Transposase, Mutator family 14 366 3.2E-98 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS17975 d31c982c56c7eee9c97107ca6a4c08e8 389 ProSitePatterns PS01007 Transposases, Mutator family, signature. 221 245 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS17975 d31c982c56c7eee9c97107ca6a4c08e8 389 Pfam PF00872 Transposase, Mutator family 14 366 3.2E-98 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS01535 d31c982c56c7eee9c97107ca6a4c08e8 389 ProSitePatterns PS01007 Transposases, Mutator family, signature. 221 245 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS01535 d31c982c56c7eee9c97107ca6a4c08e8 389 Pfam PF00872 Transposase, Mutator family 14 366 3.2E-98 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS15110 d31c982c56c7eee9c97107ca6a4c08e8 389 ProSitePatterns PS01007 Transposases, Mutator family, signature. 221 245 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS15110 d31c982c56c7eee9c97107ca6a4c08e8 389 Pfam PF00872 Transposase, Mutator family 14 366 3.2E-98 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS16590 d31c982c56c7eee9c97107ca6a4c08e8 389 ProSitePatterns PS01007 Transposases, Mutator family, signature. 221 245 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS16590 d31c982c56c7eee9c97107ca6a4c08e8 389 Pfam PF00872 Transposase, Mutator family 14 366 3.2E-98 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS00960 d31c982c56c7eee9c97107ca6a4c08e8 389 ProSitePatterns PS01007 Transposases, Mutator family, signature. 221 245 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS00960 d31c982c56c7eee9c97107ca6a4c08e8 389 Pfam PF00872 Transposase, Mutator family 14 366 3.2E-98 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS09015 d31c982c56c7eee9c97107ca6a4c08e8 389 ProSitePatterns PS01007 Transposases, Mutator family, signature. 221 245 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS09015 d31c982c56c7eee9c97107ca6a4c08e8 389 Pfam PF00872 Transposase, Mutator family 14 366 3.2E-98 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS07865 a1029b432ee6a80133bf7c2af4167132 298 SUPERFAMILY SSF48179 165 293 1.1E-29 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GTHT12_RS07865 a1029b432ee6a80133bf7c2af4167132 298 Gene3D G3DSA:3.40.50.720 2 163 1.2E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS07865 a1029b432ee6a80133bf7c2af4167132 298 PIRSF PIRSF000103 1 294 2.4E-74 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 GTHT12_RS07865 a1029b432ee6a80133bf7c2af4167132 298 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 285 4.9E-32 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 GTHT12_RS07865 a1029b432ee6a80133bf7c2af4167132 298 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 162 8.7E-49 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 GTHT12_RS07865 a1029b432ee6a80133bf7c2af4167132 298 SUPERFAMILY SSF51735 2 163 1.08E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS07865 a1029b432ee6a80133bf7c2af4167132 298 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 06-07-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 GTHT12_RS07865 a1029b432ee6a80133bf7c2af4167132 298 Gene3D G3DSA:1.10.1040.10 164 294 3.3E-33 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 GTHT12_RS12960 93864760fa40c62c6f6aa7fef75f959f 293 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 231 285 2.7E-22 T 06-07-2017 IPR019264 Domain of unknown function DUF2179 GTHT12_RS12960 93864760fa40c62c6f6aa7fef75f959f 293 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 18 225 2.6E-62 T 06-07-2017 IPR003740 Uncharacterised membrane protein YitT GTHT12_RS12960 93864760fa40c62c6f6aa7fef75f959f 293 PIRSF PIRSF006483 2 292 7.7E-90 T 06-07-2017 IPR003740 Uncharacterised membrane protein YitT GTHT12_RS11240 019fd0b3edb8ba960c563a748a153d72 343 Pfam PF09084 NMT1/THI5 like 55 266 4.6E-55 T 06-07-2017 IPR015168 SsuA/THI5-like GTHT12_RS11240 019fd0b3edb8ba960c563a748a153d72 343 SUPERFAMILY SSF53850 42 278 9.26E-43 T 06-07-2017 GTHT12_RS11240 019fd0b3edb8ba960c563a748a153d72 343 Gene3D G3DSA:3.40.190.10 1 113 5.6E-4 T 06-07-2017 GTHT12_RS11240 019fd0b3edb8ba960c563a748a153d72 343 Gene3D G3DSA:3.40.190.10 126 252 3.9E-20 T 06-07-2017 GTHT12_RS17960 fe8d7a2cd8c04e7fcf63a8dadac7d619 386 PIRSF PIRSF006078 1 377 1.3E-144 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 GTHT12_RS17960 fe8d7a2cd8c04e7fcf63a8dadac7d619 386 Gene3D G3DSA:3.90.1510.10 42 275 5.1E-101 T 06-07-2017 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 GTHT12_RS17960 fe8d7a2cd8c04e7fcf63a8dadac7d619 386 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 375 1.3E-166 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 GTHT12_RS17960 fe8d7a2cd8c04e7fcf63a8dadac7d619 386 Pfam PF02595 Glycerate kinase family 3 373 1.5E-154 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 GTHT12_RS17960 fe8d7a2cd8c04e7fcf63a8dadac7d619 386 SUPERFAMILY SSF110738 1 376 1.44E-145 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 GTHT12_RS15665 437750274824bbedf4c5c4dfe2a3cf60 390 SUPERFAMILY SSF53901 2 264 1.73E-79 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS15665 437750274824bbedf4c5c4dfe2a3cf60 390 ProSitePatterns PS00737 Thiolases signature 2. 336 352 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 GTHT12_RS15665 437750274824bbedf4c5c4dfe2a3cf60 390 Pfam PF00108 Thiolase, N-terminal domain 5 259 3.3E-80 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 GTHT12_RS15665 437750274824bbedf4c5c4dfe2a3cf60 390 Gene3D G3DSA:3.40.47.10 4 125 1.5E-73 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS15665 437750274824bbedf4c5c4dfe2a3cf60 390 Gene3D G3DSA:3.40.47.10 184 273 1.5E-73 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS15665 437750274824bbedf4c5c4dfe2a3cf60 390 SUPERFAMILY SSF53901 268 389 3.69E-43 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS15665 437750274824bbedf4c5c4dfe2a3cf60 390 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 GTHT12_RS15665 437750274824bbedf4c5c4dfe2a3cf60 390 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 388 7.1E-145 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 GTHT12_RS15665 437750274824bbedf4c5c4dfe2a3cf60 390 Gene3D G3DSA:3.40.47.10 274 389 7.1E-67 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS15665 437750274824bbedf4c5c4dfe2a3cf60 390 Gene3D G3DSA:3.40.47.10 142 183 7.1E-67 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS15665 437750274824bbedf4c5c4dfe2a3cf60 390 Pfam PF02803 Thiolase, C-terminal domain 267 388 9.5E-47 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 GTHT12_RS15665 437750274824bbedf4c5c4dfe2a3cf60 390 ProSitePatterns PS00099 Thiolases active site. 371 384 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 GTHT12_RS15665 437750274824bbedf4c5c4dfe2a3cf60 390 PIRSF PIRSF000429 1 390 9.0E-137 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 GTHT12_RS10465 646bdbd07663a57138116dbaa0d712cb 314 PIRSF PIRSF001365 1 303 2.3E-79 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 GTHT12_RS10465 646bdbd07663a57138116dbaa0d712cb 314 PRINTS PR00146 Dihydrodipicolinate synthase signature 106 122 3.7E-24 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 GTHT12_RS10465 646bdbd07663a57138116dbaa0d712cb 314 PRINTS PR00146 Dihydrodipicolinate synthase signature 38 59 3.7E-24 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 GTHT12_RS10465 646bdbd07663a57138116dbaa0d712cb 314 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 3.7E-24 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 GTHT12_RS10465 646bdbd07663a57138116dbaa0d712cb 314 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 3.7E-24 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 GTHT12_RS10465 646bdbd07663a57138116dbaa0d712cb 314 SUPERFAMILY SSF51569 3 283 3.56E-81 T 06-07-2017 GTHT12_RS10465 646bdbd07663a57138116dbaa0d712cb 314 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 136 167 - T 06-07-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS10465 646bdbd07663a57138116dbaa0d712cb 314 Gene3D G3DSA:3.20.20.70 4 285 4.9E-87 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS10465 646bdbd07663a57138116dbaa0d712cb 314 SMART SM01130 4 296 3.6E-96 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 GTHT12_RS10465 646bdbd07663a57138116dbaa0d712cb 314 Pfam PF00701 Dihydrodipicolinate synthetase family 5 283 3.3E-72 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 GTHT12_RS10465 646bdbd07663a57138116dbaa0d712cb 314 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 41 58 - T 06-07-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 GTHT12_RS14330 b072d6f241d48d480b9b5c8488709cd0 148 Pfam PF00582 Universal stress protein family 5 144 1.4E-35 T 06-07-2017 IPR006016 UspA GO:0006950 GTHT12_RS14330 b072d6f241d48d480b9b5c8488709cd0 148 Gene3D G3DSA:3.40.50.620 5 144 7.8E-45 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS14330 b072d6f241d48d480b9b5c8488709cd0 148 PRINTS PR01438 Universal stress protein signature 104 116 1.2E-19 T 06-07-2017 IPR006015 Universal stress protein A GTHT12_RS14330 b072d6f241d48d480b9b5c8488709cd0 148 PRINTS PR01438 Universal stress protein signature 5 23 1.2E-19 T 06-07-2017 IPR006015 Universal stress protein A GTHT12_RS14330 b072d6f241d48d480b9b5c8488709cd0 148 PRINTS PR01438 Universal stress protein signature 122 144 1.2E-19 T 06-07-2017 IPR006015 Universal stress protein A GTHT12_RS14330 b072d6f241d48d480b9b5c8488709cd0 148 PIRSF PIRSF006276 3 147 2.4E-19 T 06-07-2017 IPR006015 Universal stress protein A GTHT12_RS14330 b072d6f241d48d480b9b5c8488709cd0 148 SUPERFAMILY SSF52402 5 144 6.61E-35 T 06-07-2017 GTHT12_RS15560 88da2b8cb96ceb773d3ce0d98abaca7c 460 Gene3D G3DSA:3.90.780.10 282 456 8.4E-23 T 06-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 GTHT12_RS15560 88da2b8cb96ceb773d3ce0d98abaca7c 460 Pfam PF02872 5'-nucleotidase, C-terminal domain 289 430 9.1E-18 T 06-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 GTHT12_RS15560 88da2b8cb96ceb773d3ce0d98abaca7c 460 SUPERFAMILY SSF55816 283 459 1.01E-29 T 06-07-2017 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 GTHT12_RS15560 88da2b8cb96ceb773d3ce0d98abaca7c 460 PRINTS PR01607 Apyrase family signature 412 431 7.8E-22 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 GTHT12_RS15560 88da2b8cb96ceb773d3ce0d98abaca7c 460 PRINTS PR01607 Apyrase family signature 169 186 7.8E-22 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 GTHT12_RS15560 88da2b8cb96ceb773d3ce0d98abaca7c 460 PRINTS PR01607 Apyrase family signature 188 211 7.8E-22 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 GTHT12_RS15560 88da2b8cb96ceb773d3ce0d98abaca7c 460 PRINTS PR01607 Apyrase family signature 216 236 7.8E-22 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 GTHT12_RS15560 88da2b8cb96ceb773d3ce0d98abaca7c 460 PRINTS PR01607 Apyrase family signature 3 21 7.8E-22 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 GTHT12_RS15560 88da2b8cb96ceb773d3ce0d98abaca7c 460 PRINTS PR01607 Apyrase family signature 328 351 7.8E-22 T 06-07-2017 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-73621|Reactome: R-HSA-74259 GTHT12_RS15560 88da2b8cb96ceb773d3ce0d98abaca7c 460 SUPERFAMILY SSF56300 4 255 6.75E-67 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like GTHT12_RS15560 88da2b8cb96ceb773d3ce0d98abaca7c 460 Pfam PF00149 Calcineurin-like phosphoesterase 7 205 3.9E-11 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 GTHT12_RS15560 88da2b8cb96ceb773d3ce0d98abaca7c 460 PIRSF PIRSF036361 1 460 4.1E-174 T 06-07-2017 IPR011240 Phosphoesterase-related protein YunD GTHT12_RS15560 88da2b8cb96ceb773d3ce0d98abaca7c 460 Gene3D G3DSA:3.60.21.10 4 273 2.3E-63 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like GTHT12_RS01435 6db01fe8ca0963a8bd842dcc0dd28615 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 157 178 1.8E-51 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 GTHT12_RS01435 6db01fe8ca0963a8bd842dcc0dd28615 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 134 146 1.8E-51 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 GTHT12_RS01435 6db01fe8ca0963a8bd842dcc0dd28615 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 267 276 1.8E-51 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 GTHT12_RS01435 6db01fe8ca0963a8bd842dcc0dd28615 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 8 21 1.8E-51 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 GTHT12_RS01435 6db01fe8ca0963a8bd842dcc0dd28615 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 80 100 1.8E-51 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 GTHT12_RS01435 6db01fe8ca0963a8bd842dcc0dd28615 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 101 120 1.8E-51 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 GTHT12_RS01435 6db01fe8ca0963a8bd842dcc0dd28615 337 Pfam PF00814 Glycoprotease family 27 311 2.2E-105 T 06-07-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 GTHT12_RS01435 6db01fe8ca0963a8bd842dcc0dd28615 337 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 8 311 1.1E-108 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 GTHT12_RS01435 6db01fe8ca0963a8bd842dcc0dd28615 337 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 5 336 64.979 T 06-07-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 GTHT12_RS01435 6db01fe8ca0963a8bd842dcc0dd28615 337 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 7 316 8.1E-136 T 06-07-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 GTHT12_RS01435 6db01fe8ca0963a8bd842dcc0dd28615 337 ProSitePatterns PS01016 Glycoprotease family signature. 100 120 - T 06-07-2017 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 GTHT12_RS01435 6db01fe8ca0963a8bd842dcc0dd28615 337 SUPERFAMILY SSF53067 105 313 7.96E-44 T 06-07-2017 GTHT12_RS01435 6db01fe8ca0963a8bd842dcc0dd28615 337 Gene3D G3DSA:3.30.420.40 6 162 4.8E-49 T 06-07-2017 GTHT12_RS01435 6db01fe8ca0963a8bd842dcc0dd28615 337 SUPERFAMILY SSF53067 6 125 5.76E-32 T 06-07-2017 GTHT12_RS14845 32707a2228ba21f4e8fa76b81c4aadf4 78 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 1.0E-23 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor GTHT12_RS14845 32707a2228ba21f4e8fa76b81c4aadf4 78 SMART SM01234 1 68 2.5E-49 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor GTHT12_RS14845 32707a2228ba21f4e8fa76b81c4aadf4 78 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 26.243 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor GTHT12_RS14845 32707a2228ba21f4e8fa76b81c4aadf4 78 Pfam PF01809 Haemolytic domain 3 68 1.2E-32 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor GTHT12_RS14845 32707a2228ba21f4e8fa76b81c4aadf4 78 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 76 1.4E-35 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor GTHT12_RS12080 3b7295e297001f15c87307fbc8ba2785 209 Hamap MF_01804 Segregation and condensation protein B [scpB]. 1 196 35.77 T 06-07-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 GTHT12_RS12080 3b7295e297001f15c87307fbc8ba2785 209 Gene3D G3DSA:1.10.10.10 16 93 3.5E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12080 3b7295e297001f15c87307fbc8ba2785 209 Gene3D G3DSA:1.10.10.10 99 171 7.8E-37 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12080 3b7295e297001f15c87307fbc8ba2785 209 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 19 198 7.3E-58 T 06-07-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 GTHT12_RS12080 3b7295e297001f15c87307fbc8ba2785 209 SUPERFAMILY SSF46785 17 93 4.53E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12080 3b7295e297001f15c87307fbc8ba2785 209 SUPERFAMILY SSF46785 99 171 3.45E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12080 3b7295e297001f15c87307fbc8ba2785 209 Pfam PF04079 Segregation and condensation complex subunit ScpB 20 180 1.3E-60 T 06-07-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 GTHT12_RS12080 3b7295e297001f15c87307fbc8ba2785 209 PIRSF PIRSF019345 2 208 2.4E-60 T 06-07-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 GTHT12_RS10435 74c6a45c47f11065e8f5d160a3710f03 382 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 180 211 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 GTHT12_RS10435 74c6a45c47f11065e8f5d160a3710f03 382 Pfam PF13378 Enolase C-terminal domain-like 129 355 1.1E-64 T 06-07-2017 IPR029065 Enolase C-terminal domain-like GTHT12_RS10435 74c6a45c47f11065e8f5d160a3710f03 382 SMART SM00922 125 230 7.9E-23 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal GTHT12_RS10435 74c6a45c47f11065e8f5d160a3710f03 382 Gene3D G3DSA:3.20.20.120 115 349 1.0E-89 T 06-07-2017 IPR029065 Enolase C-terminal domain-like GTHT12_RS10435 74c6a45c47f11065e8f5d160a3710f03 382 SUPERFAMILY SSF51604 95 360 5.37E-82 T 06-07-2017 IPR029065 Enolase C-terminal domain-like GTHT12_RS10435 74c6a45c47f11065e8f5d160a3710f03 382 SUPERFAMILY SSF54826 1 111 1.24E-29 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS10435 74c6a45c47f11065e8f5d160a3710f03 382 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 16 107 2.1E-24 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain GTHT12_RS10435 74c6a45c47f11065e8f5d160a3710f03 382 Gene3D G3DSA:3.30.390.10 13 114 1.2E-44 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 GTHT12_RS10435 74c6a45c47f11065e8f5d160a3710f03 382 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 82 107 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 GTHT12_RS06915 6ffdb8529f8f909ac77b50a926d5fef4 592 SMART SM00382 374 566 3.4E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS06915 6ffdb8529f8f909ac77b50a926d5fef4 592 Gene3D G3DSA:1.20.1560.10 17 332 5.1E-77 T 06-07-2017 GTHT12_RS06915 6ffdb8529f8f909ac77b50a926d5fef4 592 SUPERFAMILY SSF90123 17 334 9.81E-72 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GTHT12_RS06915 6ffdb8529f8f909ac77b50a926d5fef4 592 Gene3D G3DSA:3.40.50.300 349 580 1.1E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06915 6ffdb8529f8f909ac77b50a926d5fef4 592 Pfam PF00664 ABC transporter transmembrane region 31 302 2.9E-46 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GTHT12_RS06915 6ffdb8529f8f909ac77b50a926d5fef4 592 ProSitePatterns PS00211 ABC transporters family signature. 486 500 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS06915 6ffdb8529f8f909ac77b50a926d5fef4 592 SUPERFAMILY SSF52540 339 584 4.37E-88 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06915 6ffdb8529f8f909ac77b50a926d5fef4 592 Pfam PF00005 ABC transporter 365 514 4.7E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS09615 0dc3f24dfc27130c6d59656ae624487d 434 SMART SM00388 203 269 1.5E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS09615 0dc3f24dfc27130c6d59656ae624487d 434 SUPERFAMILY SSF47384 198 266 3.34E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS09615 0dc3f24dfc27130c6d59656ae624487d 434 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 311 415 2.0E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS09615 0dc3f24dfc27130c6d59656ae624487d 434 Gene3D G3DSA:3.30.565.10 272 414 1.9E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS09615 0dc3f24dfc27130c6d59656ae624487d 434 Pfam PF00512 His Kinase A (phospho-acceptor) domain 206 265 3.9E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS09615 0dc3f24dfc27130c6d59656ae624487d 434 SMART SM00387 309 416 3.8E-32 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS09615 0dc3f24dfc27130c6d59656ae624487d 434 Gene3D G3DSA:1.10.287.130 198 265 1.4E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 GTHT12_RS09615 0dc3f24dfc27130c6d59656ae624487d 434 SUPERFAMILY SSF55874 271 414 1.31E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS09615 0dc3f24dfc27130c6d59656ae624487d 434 Pfam PF07694 5TMR of 5TMR-LYT 41 146 1.6E-6 T 06-07-2017 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 GTHT12_RS09615 0dc3f24dfc27130c6d59656ae624487d 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 374 3.4E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS09615 0dc3f24dfc27130c6d59656ae624487d 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 360 3.4E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS09615 0dc3f24dfc27130c6d59656ae624487d 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 413 3.4E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS09615 0dc3f24dfc27130c6d59656ae624487d 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 394 3.4E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 GTHT12_RS17425 d58cbec77869c121e7063ae586367d2a 617 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 353 375 7.1E-13 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 GTHT12_RS17425 d58cbec77869c121e7063ae586367d2a 617 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 55 79 7.1E-13 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 GTHT12_RS17425 d58cbec77869c121e7063ae586367d2a 617 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 411 433 7.1E-13 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 GTHT12_RS17425 d58cbec77869c121e7063ae586367d2a 617 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 81 101 7.1E-13 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 GTHT12_RS17425 d58cbec77869c121e7063ae586367d2a 617 Pfam PF00361 Proton-conducting membrane transporter 130 419 2.3E-91 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17425 d58cbec77869c121e7063ae586367d2a 617 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 61 117 1.8E-19 T 06-07-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17425 d58cbec77869c121e7063ae586367d2a 617 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 311 323 6.5E-61 T 06-07-2017 GTHT12_RS17425 d58cbec77869c121e7063ae586367d2a 617 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 154 175 6.5E-61 T 06-07-2017 GTHT12_RS17425 d58cbec77869c121e7063ae586367d2a 617 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 221 242 6.5E-61 T 06-07-2017 GTHT12_RS17425 d58cbec77869c121e7063ae586367d2a 617 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 243 269 6.5E-61 T 06-07-2017 GTHT12_RS17425 d58cbec77869c121e7063ae586367d2a 617 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 79 104 6.5E-61 T 06-07-2017 GTHT12_RS17425 d58cbec77869c121e7063ae586367d2a 617 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 412 431 6.5E-61 T 06-07-2017 GTHT12_RS17425 d58cbec77869c121e7063ae586367d2a 617 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 107 127 6.5E-61 T 06-07-2017 GTHT12_RS17425 d58cbec77869c121e7063ae586367d2a 617 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 4 608 1.9E-200 T 06-07-2017 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17845 266c7e7d2617e9c893c86d666a730136 283 Pfam PF00535 Glycosyl transferase family 2 6 164 4.7E-25 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 GTHT12_RS17845 266c7e7d2617e9c893c86d666a730136 283 Gene3D G3DSA:3.90.550.10 4 228 8.0E-46 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS17845 266c7e7d2617e9c893c86d666a730136 283 SUPERFAMILY SSF53448 5 210 8.91E-46 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS00535 9ac778b9164fbe2a549cddc4bb4f9b9b 228 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 223 4.9E-76 T 06-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 GTHT12_RS00535 9ac778b9164fbe2a549cddc4bb4f9b9b 228 Gene3D G3DSA:3.90.550.10 1 226 3.0E-78 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS00535 9ac778b9164fbe2a549cddc4bb4f9b9b 228 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 100 107 - T 06-07-2017 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 GTHT12_RS00535 9ac778b9164fbe2a549cddc4bb4f9b9b 228 SUPERFAMILY SSF53448 3 222 2.93E-64 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS00535 9ac778b9164fbe2a549cddc4bb4f9b9b 228 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 222 1.5E-76 T 06-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 GTHT12_RS00535 9ac778b9164fbe2a549cddc4bb4f9b9b 228 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 2 225 32.602 T 06-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 GTHT12_RS15440 046cf5fa4e0fc1bbe3cae0dd1f8d541c 356 SUPERFAMILY SSF51905 2 106 2.59E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS15440 046cf5fa4e0fc1bbe3cae0dd1f8d541c 356 Gene3D G3DSA:3.50.50.60 2 102 1.0E-13 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS15440 046cf5fa4e0fc1bbe3cae0dd1f8d541c 356 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 168 4.3E-7 T 06-07-2017 GTHT12_RS15440 046cf5fa4e0fc1bbe3cae0dd1f8d541c 356 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 225 239 4.3E-7 T 06-07-2017 GTHT12_RS15440 046cf5fa4e0fc1bbe3cae0dd1f8d541c 356 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 4.3E-7 T 06-07-2017 GTHT12_RS15440 046cf5fa4e0fc1bbe3cae0dd1f8d541c 356 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 273 4.3E-7 T 06-07-2017 GTHT12_RS15440 046cf5fa4e0fc1bbe3cae0dd1f8d541c 356 Gene3D G3DSA:3.50.50.60 103 294 2.2E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS15440 046cf5fa4e0fc1bbe3cae0dd1f8d541c 356 SUPERFAMILY SSF51905 83 299 1.69E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS15440 046cf5fa4e0fc1bbe3cae0dd1f8d541c 356 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 8.0E-6 T 06-07-2017 GTHT12_RS15440 046cf5fa4e0fc1bbe3cae0dd1f8d541c 356 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 251 273 8.0E-6 T 06-07-2017 GTHT12_RS15440 046cf5fa4e0fc1bbe3cae0dd1f8d541c 356 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 96 114 8.0E-6 T 06-07-2017 GTHT12_RS15440 046cf5fa4e0fc1bbe3cae0dd1f8d541c 356 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 287 4.4E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS02880 e81ba44427b230b6fcaa90629538964a 276 SUPERFAMILY SSF53448 4 267 2.25E-60 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS02880 e81ba44427b230b6fcaa90629538964a 276 Pfam PF01501 Glycosyl transferase family 8 4 252 1.6E-35 T 06-07-2017 IPR002495 Glycosyl transferase, family 8 GO:0016757 GTHT12_RS02880 e81ba44427b230b6fcaa90629538964a 276 Gene3D G3DSA:3.90.550.10 3 267 1.1E-57 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS13980 7ec342daba35834c7245aa105be1ec57 326 SUPERFAMILY SSF53850 40 273 2.22E-51 T 06-07-2017 GTHT12_RS13980 7ec342daba35834c7245aa105be1ec57 326 SMART SM00062 43 259 3.7E-12 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF GTHT12_RS13980 7ec342daba35834c7245aa105be1ec57 326 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 62 206 1.8E-17 T 06-07-2017 GTHT12_RS13980 7ec342daba35834c7245aa105be1ec57 326 Gene3D G3DSA:3.40.190.10 127 247 1.1E-31 T 06-07-2017 GTHT12_RS13980 7ec342daba35834c7245aa105be1ec57 326 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 47 323 3.6E-75 T 06-07-2017 IPR010067 Aliphatic sulfonates-binding protein GO:0006790|GO:0006810|GO:0016020 GTHT12_RS00680 b79f58897080377d462788eebdbc972c 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 9.5E-49 T 06-07-2017 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 GTHT12_RS00680 b79f58897080377d462788eebdbc972c 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 26.216 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00680 b79f58897080377d462788eebdbc972c 92 SUPERFAMILY SSF54570 3 84 2.35E-36 T 06-07-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00680 b79f58897080377d462788eebdbc972c 92 Pfam PF00203 Ribosomal protein S19 3 83 1.1E-38 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00680 b79f58897080377d462788eebdbc972c 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 06-07-2017 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00680 b79f58897080377d462788eebdbc972c 92 PIRSF PIRSF002144 1 92 1.3E-33 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00680 b79f58897080377d462788eebdbc972c 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 3.8E-25 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00680 b79f58897080377d462788eebdbc972c 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 3.8E-25 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00680 b79f58897080377d462788eebdbc972c 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 3.8E-25 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00680 b79f58897080377d462788eebdbc972c 92 Gene3D G3DSA:3.30.860.10 1 92 2.7E-43 T 06-07-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS08045 815ecb47ff4e7eff457b72efe9a2448b 47 Hamap MF_01505 Small, acid-soluble spore protein N [sspN]. 1 47 19.188 T 06-07-2017 IPR012612 Small acid-soluble spore protein, SspN GO:0030436|GO:0042601 GTHT12_RS08045 815ecb47ff4e7eff457b72efe9a2448b 47 Pfam PF08177 Small acid-soluble spore protein N family 1 46 3.7E-25 T 06-07-2017 IPR012612 Small acid-soluble spore protein, SspN GO:0030436|GO:0042601 GTHT12_RS15070 023ccf42d4fb66d0547f942899b85913 147 Pfam PF13673 Acetyltransferase (GNAT) domain 32 138 4.6E-12 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS15070 023ccf42d4fb66d0547f942899b85913 147 Gene3D G3DSA:3.40.630.30 4 140 9.5E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS15070 023ccf42d4fb66d0547f942899b85913 147 SUPERFAMILY SSF55729 4 138 5.56E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS09835 4b4017e7fc2ce11bb153cc1eeb04d9a7 281 Pfam PF00106 short chain dehydrogenase 11 218 8.2E-48 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS09835 4b4017e7fc2ce11bb153cc1eeb04d9a7 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 196 1.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS09835 4b4017e7fc2ce11bb153cc1eeb04d9a7 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 167 1.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS09835 4b4017e7fc2ce11bb153cc1eeb04d9a7 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 215 1.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS09835 4b4017e7fc2ce11bb153cc1eeb04d9a7 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS09835 4b4017e7fc2ce11bb153cc1eeb04d9a7 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 238 258 1.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS09835 4b4017e7fc2ce11bb153cc1eeb04d9a7 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.7E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS09835 4b4017e7fc2ce11bb153cc1eeb04d9a7 281 SUPERFAMILY SSF51735 9 277 1.04E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS09835 4b4017e7fc2ce11bb153cc1eeb04d9a7 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 3.5E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS09835 4b4017e7fc2ce11bb153cc1eeb04d9a7 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 177 196 3.5E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS09835 4b4017e7fc2ce11bb153cc1eeb04d9a7 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 165 3.5E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS09835 4b4017e7fc2ce11bb153cc1eeb04d9a7 281 Gene3D G3DSA:3.40.50.720 6 277 1.4E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS09835 4b4017e7fc2ce11bb153cc1eeb04d9a7 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 164 192 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GTHT12_RS15415 7f237d976ce260cdd8fcbfc203be98a1 407 SUPERFAMILY SSF51905 220 336 1.58E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS15415 7f237d976ce260cdd8fcbfc203be98a1 407 SUPERFAMILY SSF51905 8 178 1.58E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS15415 7f237d976ce260cdd8fcbfc203be98a1 407 Gene3D G3DSA:3.50.50.60 110 335 1.7E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS15415 7f237d976ce260cdd8fcbfc203be98a1 407 Gene3D G3DSA:3.50.50.60 6 109 2.4E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS15415 7f237d976ce260cdd8fcbfc203be98a1 407 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 327 5.3E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS15415 7f237d976ce260cdd8fcbfc203be98a1 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 3.0E-6 T 06-07-2017 GTHT12_RS15415 7f237d976ce260cdd8fcbfc203be98a1 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 3.0E-6 T 06-07-2017 GTHT12_RS15415 7f237d976ce260cdd8fcbfc203be98a1 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 161 179 3.0E-6 T 06-07-2017 GTHT12_RS02975 9d9867d75aaa186fd52dcb464f473bed 63 Pfam PF04259 Small, acid-soluble spore protein, gamma-type 11 61 4.6E-17 T 06-07-2017 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 GTHT12_RS02975 9d9867d75aaa186fd52dcb464f473bed 63 TIGRFAM TIGR01442 SASP_gamma: small, acid-soluble spore protein, gamma-type 11 61 1.1E-14 T 06-07-2017 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 GTHT12_RS11900 7869f49fca4d9250298438f34774f426 167 Pfam PF00719 Inorganic pyrophosphatase 11 162 7.6E-55 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 GTHT12_RS11900 7869f49fca4d9250298438f34774f426 167 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 6 162 36.347 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 GTHT12_RS11900 7869f49fca4d9250298438f34774f426 167 SUPERFAMILY SSF50324 4 164 3.01E-62 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 GTHT12_RS11900 7869f49fca4d9250298438f34774f426 167 Gene3D G3DSA:3.90.80.10 4 163 5.8E-58 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 GTHT12_RS11900 7869f49fca4d9250298438f34774f426 167 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 57 63 - T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 GTHT12_RS06960 00d4e412e68fcd5d970ec5cd3d9bfa75 451 Pfam PF02378 Phosphotransferase system, EIIC 29 361 1.1E-76 T 06-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 GTHT12_RS06960 00d4e412e68fcd5d970ec5cd3d9bfa75 451 PIRSF PIRSF006351 1 445 3.0E-153 T 06-07-2017 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 GTHT12_RS06960 00d4e412e68fcd5d970ec5cd3d9bfa75 451 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 436 2.5E-184 T 06-07-2017 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 GTHT12_RS06960 00d4e412e68fcd5d970ec5cd3d9bfa75 451 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 12 436 2.5E-184 T 06-07-2017 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 GTHT12_RS09435 947cdc13c6580d84f0af936a43022519 401 PIRSF PIRSF036428 1 399 3.1E-120 T 06-07-2017 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841 GTHT12_RS09435 947cdc13c6580d84f0af936a43022519 401 Gene3D G3DSA:3.40.1010.10 2 102 1.4E-21 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS09435 947cdc13c6580d84f0af936a43022519 401 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 186 1.2E-17 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS09435 947cdc13c6580d84f0af936a43022519 401 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 6 198 2.1E-57 T 06-07-2017 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 GTHT12_RS09435 947cdc13c6580d84f0af936a43022519 401 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 227 347 9.6E-36 T 06-07-2017 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 GTHT12_RS09435 947cdc13c6580d84f0af936a43022519 401 SUPERFAMILY SSF53790 5 200 5.5E-37 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS09435 947cdc13c6580d84f0af936a43022519 401 Gene3D G3DSA:3.40.50.150 216 399 2.2E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS09435 947cdc13c6580d84f0af936a43022519 401 SUPERFAMILY SSF53335 207 372 5.37E-26 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS09435 947cdc13c6580d84f0af936a43022519 401 Gene3D G3DSA:3.30.950.10 103 201 3.0E-24 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS00185 17fa17c13cbab87cd18a6c77bc0ec04d 120 PIRSF PIRSF021439 4 120 9.3E-42 T 06-07-2017 IPR010377 Initiation control protein YabA GO:0006260 GTHT12_RS00185 17fa17c13cbab87cd18a6c77bc0ec04d 120 Gene3D G3DSA:1.20.5.490 29 53 9.6E-4 T 06-07-2017 GTHT12_RS00185 17fa17c13cbab87cd18a6c77bc0ec04d 120 Hamap MF_01159 Initiation-control protein YabA. 4 119 23.658 T 06-07-2017 IPR010377 Initiation control protein YabA GO:0006260 GTHT12_RS00185 17fa17c13cbab87cd18a6c77bc0ec04d 120 Pfam PF06156 Protein of unknown function (DUF972) 5 115 2.6E-37 T 06-07-2017 IPR010377 Initiation control protein YabA GO:0006260 GTHT12_RS11505 70316cf543da629678cd0b84a253e759 56 Pfam PF14084 Protein of unknown function (DUF4264) 4 56 1.1E-25 T 06-07-2017 IPR012190 Uncharacterised conserved protein UCP036698, YpmA GTHT12_RS11505 70316cf543da629678cd0b84a253e759 56 PIRSF PIRSF036698 1 56 2.0E-36 T 06-07-2017 IPR012190 Uncharacterised conserved protein UCP036698, YpmA GTHT12_RS03605 c3a6c93933389047bd9d8c7fd0800bc7 299 Gene3D G3DSA:3.40.50.300 2 224 6.8E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03605 c3a6c93933389047bd9d8c7fd0800bc7 299 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS03605 c3a6c93933389047bd9d8c7fd0800bc7 299 Pfam PF00005 ABC transporter 19 158 1.1E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS03605 c3a6c93933389047bd9d8c7fd0800bc7 299 SMART SM00382 27 206 8.8E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS03605 c3a6c93933389047bd9d8c7fd0800bc7 299 Pfam PF13732 Domain of unknown function (DUF4162) 212 294 3.7E-19 T 06-07-2017 IPR025302 Domain of unknown function DUF4162 GTHT12_RS03605 c3a6c93933389047bd9d8c7fd0800bc7 299 SUPERFAMILY SSF52540 3 223 1.89E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13650 efacb782f77aeeb8aed3e0285837bcea 267 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 264 2.2E-127 T 06-07-2017 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 GTHT12_RS13650 efacb782f77aeeb8aed3e0285837bcea 267 PIRSF PIRSF003092 1 267 1.0E-96 T 06-07-2017 IPR025501 ATP binding protein MinD GTHT12_RS13650 efacb782f77aeeb8aed3e0285837bcea 267 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 210 7.9E-37 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain GTHT12_RS13650 efacb782f77aeeb8aed3e0285837bcea 267 SUPERFAMILY SSF52540 5 264 7.02E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13650 efacb782f77aeeb8aed3e0285837bcea 267 Gene3D G3DSA:3.40.50.300 3 241 4.5E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18595 ed3d096faf37badc7f2ab1c20ea99ae7 708 Gene3D G3DSA:3.40.50.300 94 222 1.4E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18595 ed3d096faf37badc7f2ab1c20ea99ae7 708 Gene3D G3DSA:3.40.50.300 352 549 1.4E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18595 ed3d096faf37badc7f2ab1c20ea99ae7 708 SUPERFAMILY SSF52540 124 544 9.82E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18595 ed3d096faf37badc7f2ab1c20ea99ae7 708 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 126 550 3.2E-90 T 06-07-2017 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 GTHT12_RS18940 ed3d096faf37badc7f2ab1c20ea99ae7 708 Gene3D G3DSA:3.40.50.300 94 222 1.4E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18940 ed3d096faf37badc7f2ab1c20ea99ae7 708 Gene3D G3DSA:3.40.50.300 352 549 1.4E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18940 ed3d096faf37badc7f2ab1c20ea99ae7 708 SUPERFAMILY SSF52540 124 544 9.82E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18940 ed3d096faf37badc7f2ab1c20ea99ae7 708 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 126 550 3.2E-90 T 06-07-2017 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 GTHT12_RS14850 99a799304d573fe0a7c93f26fbd5a97f 324 PRINTS PR00691 Adhesin B signature 80 99 2.1E-8 T 06-07-2017 IPR006129 Adhesin B GO:0007155 GTHT12_RS14850 99a799304d573fe0a7c93f26fbd5a97f 324 PRINTS PR00691 Adhesin B signature 61 79 2.1E-8 T 06-07-2017 IPR006129 Adhesin B GO:0007155 GTHT12_RS14850 99a799304d573fe0a7c93f26fbd5a97f 324 PRINTS PR00691 Adhesin B signature 302 320 2.1E-8 T 06-07-2017 IPR006129 Adhesin B GO:0007155 GTHT12_RS14850 99a799304d573fe0a7c93f26fbd5a97f 324 PRINTS PR00691 Adhesin B signature 36 57 2.1E-8 T 06-07-2017 IPR006129 Adhesin B GO:0007155 GTHT12_RS14850 99a799304d573fe0a7c93f26fbd5a97f 324 Gene3D G3DSA:3.40.50.1980 38 205 6.9E-55 T 06-07-2017 GTHT12_RS14850 99a799304d573fe0a7c93f26fbd5a97f 324 SUPERFAMILY SSF53807 35 323 9.32E-80 T 06-07-2017 GTHT12_RS14850 99a799304d573fe0a7c93f26fbd5a97f 324 Pfam PF01297 Zinc-uptake complex component A periplasmic 39 322 1.5E-71 T 06-07-2017 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 GTHT12_RS14850 99a799304d573fe0a7c93f26fbd5a97f 324 PRINTS PR00690 Adhesin family signature 67 80 1.0E-6 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 GTHT12_RS14850 99a799304d573fe0a7c93f26fbd5a97f 324 PRINTS PR00690 Adhesin family signature 36 54 1.0E-6 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 GTHT12_RS14850 99a799304d573fe0a7c93f26fbd5a97f 324 PRINTS PR00690 Adhesin family signature 80 97 1.0E-6 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 GTHT12_RS14850 99a799304d573fe0a7c93f26fbd5a97f 324 PRINTS PR00690 Adhesin family signature 262 280 1.0E-6 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 GTHT12_RS14850 99a799304d573fe0a7c93f26fbd5a97f 324 Gene3D G3DSA:3.40.190.10 4 37 2.5E-4 T 06-07-2017 GTHT12_RS14850 99a799304d573fe0a7c93f26fbd5a97f 324 Gene3D G3DSA:3.40.50.1980 206 323 6.1E-31 T 06-07-2017 GTHT12_RS03705 5d286c0ec5a38639d1b89b5fa33c13f7 794 SUPERFAMILY SSF58104 291 526 9.68E-8 T 06-07-2017 GTHT12_RS03705 5d286c0ec5a38639d1b89b5fa33c13f7 794 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 575 773 1.1E-64 T 06-07-2017 IPR017501 Phage infection protein, YhgE, C-terminal GTHT12_RS03705 5d286c0ec5a38639d1b89b5fa33c13f7 794 Gene3D G3DSA:2.150.10.10 470 538 4.5E-5 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal GTHT12_RS03705 5d286c0ec5a38639d1b89b5fa33c13f7 794 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 5 167 1.9E-60 T 06-07-2017 IPR017500 Phage infection protein, YhgE, N-terminal GTHT12_RS03705 5d286c0ec5a38639d1b89b5fa33c13f7 794 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 245 267 2.7E-4 T 06-07-2017 IPR023908 xxxLxxG heptad repeat GTHT12_RS03705 5d286c0ec5a38639d1b89b5fa33c13f7 794 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 494 521 1.7E-6 T 06-07-2017 IPR023908 xxxLxxG heptad repeat GTHT12_RS03705 5d286c0ec5a38639d1b89b5fa33c13f7 794 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 471 493 1.1E-5 T 06-07-2017 IPR023908 xxxLxxG heptad repeat GTHT12_RS03705 5d286c0ec5a38639d1b89b5fa33c13f7 794 SUPERFAMILY SSF101967 463 541 2.09E-8 T 06-07-2017 GTHT12_RS03705 5d286c0ec5a38639d1b89b5fa33c13f7 794 Pfam PF12698 ABC-2 family transporter protein 580 769 3.4E-13 T 06-07-2017 GTHT12_RS03705 5d286c0ec5a38639d1b89b5fa33c13f7 794 Pfam PF12698 ABC-2 family transporter protein 21 156 1.4E-13 T 06-07-2017 GTHT12_RS14375 24b6230a8c49274fe749eecbc942be81 166 Hamap MF_00269 Probable thiol peroxidase [tpx]. 3 163 39.264 T 06-07-2017 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 GTHT12_RS14375 24b6230a8c49274fe749eecbc942be81 166 Pfam PF08534 Redoxin 20 159 7.2E-25 T 06-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 GTHT12_RS14375 24b6230a8c49274fe749eecbc942be81 166 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 06-07-2017 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 GTHT12_RS14375 24b6230a8c49274fe749eecbc942be81 166 SUPERFAMILY SSF52833 1 160 2.99E-48 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS14375 24b6230a8c49274fe749eecbc942be81 166 Gene3D G3DSA:3.40.30.10 2 165 1.1E-50 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS00340 632a6fe6105f24119a103b261384a956 132 Gene3D G3DSA:2.40.50.140 2 83 2.6E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS00340 632a6fe6105f24119a103b261384a956 132 Pfam PF00575 S1 RNA binding domain 4 74 1.8E-21 T 06-07-2017 IPR003029 S1 domain GO:0003676 GTHT12_RS00340 632a6fe6105f24119a103b261384a956 132 SUPERFAMILY SSF50249 4 81 5.7E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS00340 632a6fe6105f24119a103b261384a956 132 SMART SM00316 4 74 1.3E-26 T 06-07-2017 IPR022967 RNA-binding domain, S1 GTHT12_RS17305 96fcc17afa251081e6af0c0f3e28930f 261 Gene3D G3DSA:3.40.50.1110 86 258 5.1E-14 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain GTHT12_RS17305 96fcc17afa251081e6af0c0f3e28930f 261 SUPERFAMILY SSF52266 86 258 8.33E-19 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain GTHT12_RS17305 96fcc17afa251081e6af0c0f3e28930f 261 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 89 236 1.3E-6 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain GTHT12_RS04235 84ee8b4a4e214feffb9c40b5472f4323 59 Pfam PF14168 YjzC-like protein 1 55 1.3E-28 T 06-07-2017 IPR025549 YjzC-like protein GTHT12_RS06180 ff9119fdb753c4950498c60f2fe4acd6 314 Gene3D G3DSA:3.40.366.10 197 307 2.0E-76 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 GTHT12_RS06180 ff9119fdb753c4950498c60f2fe4acd6 314 Gene3D G3DSA:3.40.366.10 2 121 2.0E-76 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 GTHT12_RS06180 ff9119fdb753c4950498c60f2fe4acd6 314 Pfam PF00698 Acyl transferase domain 6 285 3.1E-44 T 06-07-2017 IPR014043 Acyl transferase GTHT12_RS06180 ff9119fdb753c4950498c60f2fe4acd6 314 PIRSF PIRSF000446 1 311 5.0E-115 T 06-07-2017 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 GTHT12_RS06180 ff9119fdb753c4950498c60f2fe4acd6 314 SUPERFAMILY SSF55048 128 193 1.83E-16 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 GTHT12_RS06180 ff9119fdb753c4950498c60f2fe4acd6 314 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 291 2.0E-111 T 06-07-2017 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 GTHT12_RS06180 ff9119fdb753c4950498c60f2fe4acd6 314 Gene3D G3DSA:3.30.70.250 125 196 6.7E-30 T 06-07-2017 GTHT12_RS06180 ff9119fdb753c4950498c60f2fe4acd6 314 SUPERFAMILY SSF52151 4 121 4.97E-81 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 GTHT12_RS06180 ff9119fdb753c4950498c60f2fe4acd6 314 SUPERFAMILY SSF52151 190 310 4.97E-81 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 GTHT12_RS06180 ff9119fdb753c4950498c60f2fe4acd6 314 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 314 4.1E-52 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain GTHT12_RS06050 7db1440f2c019694c5432025067ebe71 579 Pfam PF05670 Domain of unknown function (DUF814) 454 538 1.4E-30 T 06-07-2017 IPR008532 Domain of unknown function DUF814 GTHT12_RS06050 7db1440f2c019694c5432025067ebe71 579 Gene3D G3DSA:3.40.970.40 239 289 2.7E-23 T 06-07-2017 GTHT12_RS06050 7db1440f2c019694c5432025067ebe71 579 Gene3D G3DSA:1.10.8.50 169 236 2.9E-28 T 06-07-2017 GTHT12_RS06050 7db1440f2c019694c5432025067ebe71 579 Gene3D G3DSA:2.30.310.10 1 166 3.4E-62 T 06-07-2017 GTHT12_RS06050 7db1440f2c019694c5432025067ebe71 579 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 444 1.2E-165 T 06-07-2017 GTHT12_RS06515 35eb8f1899b82b6fa5a2ca5ebad02d44 417 SUPERFAMILY SSF50156 157 266 5.13E-19 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS06515 35eb8f1899b82b6fa5a2ca5ebad02d44 417 Pfam PF02163 Peptidase family M50 7 403 7.0E-78 T 06-07-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 GTHT12_RS06515 35eb8f1899b82b6fa5a2ca5ebad02d44 417 Pfam PF13180 PDZ domain 200 264 5.1E-8 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS06515 35eb8f1899b82b6fa5a2ca5ebad02d44 417 SMART SM00228 186 256 3.9E-7 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS06515 35eb8f1899b82b6fa5a2ca5ebad02d44 417 Gene3D G3DSA:2.30.42.10 166 266 4.7E-22 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS06515 35eb8f1899b82b6fa5a2ca5ebad02d44 417 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 3 416 9.2E-113 T 06-07-2017 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 GTHT12_RS04090 0304b229e2d7c987fcaeea29fccf1830 389 Pfam PF14449 Pre-toxin TG 86 155 5.2E-16 T 06-07-2017 IPR027797 Pre-toxin TG domain GTHT12_RS04090 0304b229e2d7c987fcaeea29fccf1830 389 Gene3D G3DSA:1.10.287.1060 3 94 4.8E-4 T 06-07-2017 GTHT12_RS04090 0304b229e2d7c987fcaeea29fccf1830 389 SUPERFAMILY SSF140453 2 92 8.5E-7 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like GTHT12_RS05530 a6a9638776911d73425dc2488cd45ce5 80 Pfam PF03698 Uncharacterised protein family (UPF0180) 3 78 6.4E-31 T 06-07-2017 IPR005370 Uncharacterised protein family UPF0180 GTHT12_RS05530 a6a9638776911d73425dc2488cd45ce5 80 Hamap MF_00506 UPF0180 protein . 1 79 29.54 T 06-07-2017 IPR005370 Uncharacterised protein family UPF0180 GTHT12_RS05530 a6a9638776911d73425dc2488cd45ce5 80 ProDom PD059670 UPF0180 YKUS BA1413/GBAA1413/BAS1304 YKUS-LIKE BT9727_1277 BCE1513 GK1051 BH2667 ABC2430 BCE33L1278 1 47 2.0E-18 T 06-07-2017 IPR005370 Uncharacterised protein family UPF0180 GTHT12_RS09455 f978a31119a02b1542bb4f5c21aad523 274 Pfam PF01903 CbiX 138 241 2.9E-26 T 06-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 GTHT12_RS09455 f978a31119a02b1542bb4f5c21aad523 274 Pfam PF01903 CbiX 9 114 1.2E-24 T 06-07-2017 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 GTHT12_RS09455 f978a31119a02b1542bb4f5c21aad523 274 SUPERFAMILY SSF53800 1 249 2.51E-54 T 06-07-2017 GTHT12_RS09455 f978a31119a02b1542bb4f5c21aad523 274 Gene3D G3DSA:3.40.50.1400 1 125 4.8E-31 T 06-07-2017 GTHT12_RS09455 f978a31119a02b1542bb4f5c21aad523 274 Gene3D G3DSA:3.40.50.1400 130 250 2.7E-31 T 06-07-2017 GTHT12_RS11995 127a3fe2b03b464674445c617f51a358 454 Pfam PF02378 Phosphotransferase system, EIIC 9 293 3.3E-79 T 06-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 GTHT12_RS11995 127a3fe2b03b464674445c617f51a358 454 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 395 412 - T 06-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 GTHT12_RS11995 127a3fe2b03b464674445c617f51a358 454 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 1 453 9.1E-194 T 06-07-2017 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 GTHT12_RS11995 127a3fe2b03b464674445c617f51a358 454 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 350 442 3.8E-25 T 06-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 GTHT12_RS11995 127a3fe2b03b464674445c617f51a358 454 Gene3D G3DSA:3.30.1360.60 378 454 3.4E-28 T 06-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 GTHT12_RS11995 127a3fe2b03b464674445c617f51a358 454 SUPERFAMILY SSF55604 382 453 5.1E-21 T 06-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 GTHT12_RS11995 127a3fe2b03b464674445c617f51a358 454 Pfam PF00367 phosphotransferase system, EIIB 385 417 6.4E-15 T 06-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 GTHT12_RS18105 7322ec4d41c2a0184fbbeb3b446eb011 264 Gene3D G3DSA:3.60.15.10 2 231 9.8E-43 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS18105 7322ec4d41c2a0184fbbeb3b446eb011 264 Pfam PF00753 Metallo-beta-lactamase superfamily 12 218 8.6E-24 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS18105 7322ec4d41c2a0184fbbeb3b446eb011 264 SMART SM00849 13 218 3.2E-13 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS18105 7322ec4d41c2a0184fbbeb3b446eb011 264 SUPERFAMILY SSF56281 3 241 6.29E-49 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS02265 a0795e956651f408f00a17cdd50166d3 563 Pfam PF13667 ThiC-associated domain 9 86 4.0E-33 T 06-07-2017 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 GTHT12_RS02265 a0795e956651f408f00a17cdd50166d3 563 Pfam PF01964 Radical SAM ThiC family 116 536 7.6E-205 T 06-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 GTHT12_RS02265 a0795e956651f408f00a17cdd50166d3 563 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 115 542 56.923 T 06-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 GTHT12_RS02265 a0795e956651f408f00a17cdd50166d3 563 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 115 539 3.0E-220 T 06-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 GTHT12_RS13305 5841a8c1a45aa0cf171d839f7a94030e 236 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 227 5.0E-108 T 06-07-2017 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 GTHT12_RS13305 5841a8c1a45aa0cf171d839f7a94030e 236 Pfam PF01048 Phosphorylase superfamily 3 227 3.7E-51 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 GTHT12_RS13305 5841a8c1a45aa0cf171d839f7a94030e 236 SUPERFAMILY SSF53167 1 228 6.41E-73 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 GTHT12_RS13305 5841a8c1a45aa0cf171d839f7a94030e 236 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 2 230 47.702 T 06-07-2017 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 GTHT12_RS13305 5841a8c1a45aa0cf171d839f7a94030e 236 Gene3D G3DSA:3.40.50.1580 1 232 3.3E-79 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 GTHT12_RS11715 778d08c3ec36bb2aaa4d59ea290a1824 492 PIRSF PIRSF007466 1 492 2.6E-274 T 06-07-2017 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 GTHT12_RS11715 778d08c3ec36bb2aaa4d59ea290a1824 492 SUPERFAMILY SSF52540 19 236 5.04E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11715 778d08c3ec36bb2aaa4d59ea290a1824 492 Gene3D G3DSA:3.40.50.300 18 223 3.8E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11715 778d08c3ec36bb2aaa4d59ea290a1824 492 Pfam PF09547 Stage IV sporulation protein A (spore_IV_A) 2 492 9.1E-230 T 06-07-2017 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 GTHT12_RS11715 778d08c3ec36bb2aaa4d59ea290a1824 492 TIGRFAM TIGR02836 spore_IV_A: stage IV sporulation protein A 1 492 2.8E-267 T 06-07-2017 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 GTHT12_RS13400 c2f42e2f303019d0b021d832fe597692 157 SUPERFAMILY SSF50346 82 137 1.73E-7 T 06-07-2017 IPR011033 PRC-barrel-like GTHT12_RS13400 c2f42e2f303019d0b021d832fe597692 157 SUPERFAMILY SSF50346 1 69 1.57E-9 T 06-07-2017 IPR011033 PRC-barrel-like GTHT12_RS13400 c2f42e2f303019d0b021d832fe597692 157 Gene3D G3DSA:2.30.30.240 2 67 4.5E-7 T 06-07-2017 GTHT12_RS13400 c2f42e2f303019d0b021d832fe597692 157 Pfam PF05239 PRC-barrel domain 92 136 1.0E-5 T 06-07-2017 IPR027275 PRC-barrel domain GTHT12_RS13400 c2f42e2f303019d0b021d832fe597692 157 Pfam PF05239 PRC-barrel domain 3 69 9.8E-10 T 06-07-2017 IPR027275 PRC-barrel domain GTHT12_RS17880 1225db6e7fcacc1cd908bb5680436602 485 Pfam PF00474 Sodium:solute symporter family 30 428 4.2E-109 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 GTHT12_RS17880 1225db6e7fcacc1cd908bb5680436602 485 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 30 428 4.6E-99 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 GTHT12_RS17880 1225db6e7fcacc1cd908bb5680436602 485 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 152 177 - T 06-07-2017 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 GTHT12_RS17880 1225db6e7fcacc1cd908bb5680436602 485 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 410 430 - T 06-07-2017 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 GTHT12_RS17880 1225db6e7fcacc1cd908bb5680436602 485 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 2 483 1.2E-223 T 06-07-2017 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 GTHT12_RS13440 508c0f84d02bd6765093f37d9ba53c32 216 Pfam PF13921 Myb-like DNA-binding domain 8 57 1.2E-5 T 06-07-2017 GTHT12_RS13440 508c0f84d02bd6765093f37d9ba53c32 216 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 2 81 2.0E-44 T 06-07-2017 IPR014243 Transcription factor, RsfA GTHT12_RS13440 508c0f84d02bd6765093f37d9ba53c32 216 Gene3D G3DSA:1.10.10.60 7 89 2.4E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS02455 6c4dbc16b5b0de84a1bb9e108cdc4171 203 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 23 195 40.396 T 06-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 GTHT12_RS02455 6c4dbc16b5b0de84a1bb9e108cdc4171 203 Gene3D G3DSA:3.40.50.300 1 198 1.5E-94 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS02455 6c4dbc16b5b0de84a1bb9e108cdc4171 203 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 7 191 1.7E-87 T 06-07-2017 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 GTHT12_RS02455 6c4dbc16b5b0de84a1bb9e108cdc4171 203 Pfam PF01583 Adenylylsulphate kinase 25 177 1.8E-74 T 06-07-2017 GTHT12_RS02455 6c4dbc16b5b0de84a1bb9e108cdc4171 203 SUPERFAMILY SSF52540 23 194 2.15E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13790 5b5329e033efe58dd380abf6205aeff5 354 TIGRFAM TIGR02907 spore_VI_D: stage VI sporulation protein D 6 345 1.2E-123 T 06-07-2017 IPR014256 Sporulation stage VI, protein D GTHT12_RS13790 5b5329e033efe58dd380abf6205aeff5 354 SUPERFAMILY SSF54106 301 345 4.97E-9 T 06-07-2017 IPR018392 LysM domain GTHT12_RS13790 5b5329e033efe58dd380abf6205aeff5 354 Gene3D G3DSA:3.10.350.10 304 345 1.1E-11 T 06-07-2017 IPR018392 LysM domain GTHT12_RS13790 5b5329e033efe58dd380abf6205aeff5 354 Pfam PF01476 LysM domain 303 345 2.3E-8 T 06-07-2017 IPR018392 LysM domain GTHT12_RS13790 5b5329e033efe58dd380abf6205aeff5 354 SMART SM00257 301 345 3.0E-8 T 06-07-2017 IPR018392 LysM domain GTHT12_RS11455 9797f740c0b093094943e13a61a9ad12 120 Pfam PF08807 Bacterial domain of unknown function (DUF1798) 9 115 1.3E-36 T 06-07-2017 IPR014913 Protein of unknown function DUF1798 GTHT12_RS11455 9797f740c0b093094943e13a61a9ad12 120 SUPERFAMILY SSF140415 4 119 1.7E-42 T 06-07-2017 IPR023351 YppE-like domain GTHT12_RS11455 9797f740c0b093094943e13a61a9ad12 120 Gene3D G3DSA:1.20.120.440 3 119 9.8E-43 T 06-07-2017 IPR023351 YppE-like domain GTHT12_RS04885 e002edb1e72d272e759f2708692f678d 430 TIGRFAM TIGR00883 2A0106: MFS transporter, metabolite:H+ symporter (MHS) family protein 16 409 3.5E-135 T 06-07-2017 IPR004736 Citrate-proton symport GO:0005215|GO:0006810|GO:0016021 GTHT12_RS04885 e002edb1e72d272e759f2708692f678d 430 Pfam PF07690 Major Facilitator Superfamily 244 420 6.4E-15 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS04885 e002edb1e72d272e759f2708692f678d 430 Gene3D G3DSA:1.20.1250.20 7 212 4.0E-25 T 06-07-2017 GTHT12_RS04885 e002edb1e72d272e759f2708692f678d 430 Gene3D G3DSA:1.20.1250.20 233 425 3.9E-25 T 06-07-2017 GTHT12_RS04885 e002edb1e72d272e759f2708692f678d 430 ProSitePatterns PS00216 Sugar transport proteins signature 1. 289 306 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 GTHT12_RS04885 e002edb1e72d272e759f2708692f678d 430 ProSitePatterns PS00217 Sugar transport proteins signature 2. 120 145 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 GTHT12_RS04885 e002edb1e72d272e759f2708692f678d 430 SUPERFAMILY SSF103473 6 422 1.96E-70 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS04885 e002edb1e72d272e759f2708692f678d 430 Pfam PF00083 Sugar (and other) transporter 10 210 7.7E-26 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 GTHT12_RS11450 76de5413328c8babf914cb3c4580e05b 66 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 57 3.0E-5 T 06-07-2017 GTHT12_RS11450 76de5413328c8babf914cb3c4580e05b 66 Pfam PF14178 YppF-like protein 1 59 1.9E-28 T 06-07-2017 IPR025553 YppF-like protein GTHT12_RS03890 5ba68a30e9b512c3d05710b6ec2845e3 286 SMART SM00342 197 280 1.5E-28 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 GTHT12_RS03890 5ba68a30e9b512c3d05710b6ec2845e3 286 Pfam PF12833 Helix-turn-helix domain 203 281 4.1E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 GTHT12_RS03890 5ba68a30e9b512c3d05710b6ec2845e3 286 SUPERFAMILY SSF46689 233 281 1.79E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS03890 5ba68a30e9b512c3d05710b6ec2845e3 286 Gene3D G3DSA:1.10.10.60 180 233 3.2E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS03890 5ba68a30e9b512c3d05710b6ec2845e3 286 Gene3D G3DSA:1.10.10.60 234 281 2.6E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS03890 5ba68a30e9b512c3d05710b6ec2845e3 286 Gene3D G3DSA:2.60.120.280 2 171 9.3E-29 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 GTHT12_RS03890 5ba68a30e9b512c3d05710b6ec2845e3 286 Pfam PF02311 AraC-like ligand binding domain 27 91 5.9E-5 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 GTHT12_RS03890 5ba68a30e9b512c3d05710b6ec2845e3 286 SUPERFAMILY SSF46689 184 230 1.49E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS03890 5ba68a30e9b512c3d05710b6ec2845e3 286 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 249 264 3.3E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 GTHT12_RS03890 5ba68a30e9b512c3d05710b6ec2845e3 286 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 264 280 3.3E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 GTHT12_RS03890 5ba68a30e9b512c3d05710b6ec2845e3 286 SUPERFAMILY SSF51215 1 170 7.98E-23 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 GTHT12_RS04085 4f20041801c1ee6f9d61d1322d0d5db2 372 Gene3D G3DSA:3.20.20.70 4 348 1.9E-75 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS04085 4f20041801c1ee6f9d61d1322d0d5db2 372 TIGRFAM TIGR04053 sam_11: radical SAM protein, BA_1875 family 3 361 7.4E-160 T 06-07-2017 IPR027634 Radical SAM protein, BA_1875 family GTHT12_RS04085 4f20041801c1ee6f9d61d1322d0d5db2 372 PIRSF PIRSF037420 1 371 9.4E-102 T 06-07-2017 IPR017200 Coenzyme PQQ synthesis protein E GTHT12_RS04085 4f20041801c1ee6f9d61d1322d0d5db2 372 SMART SM00729 9 211 0.0017 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 GTHT12_RS04085 4f20041801c1ee6f9d61d1322d0d5db2 372 Pfam PF04055 Radical SAM superfamily 15 170 5.1E-19 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 GTHT12_RS04085 4f20041801c1ee6f9d61d1322d0d5db2 372 Pfam PF13353 4Fe-4S single cluster domain 12 84 2.6E-6 T 06-07-2017 GTHT12_RS04085 4f20041801c1ee6f9d61d1322d0d5db2 372 Pfam PF13186 Iron-sulfur cluster-binding domain 277 330 9.6E-6 T 06-07-2017 IPR023885 4Fe4S-binding SPASM domain GTHT12_RS04085 4f20041801c1ee6f9d61d1322d0d5db2 372 SUPERFAMILY SSF102114 8 338 8.11E-67 T 06-07-2017 GTHT12_RS18440 5776c2afebabc2c36922d4ac1aeb6262 329 SUPERFAMILY SSF55831 6 219 5.23E-27 T 06-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 GTHT12_RS18440 5776c2afebabc2c36922d4ac1aeb6262 329 Pfam PF00303 Thymidylate synthase 110 221 1.8E-10 T 06-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 GTHT12_RS18440 5776c2afebabc2c36922d4ac1aeb6262 329 Gene3D G3DSA:3.30.572.10 7 221 2.2E-23 T 06-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 GTHT12_RS12995 38497e98f55f8916c3195c5985b23c60 253 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 42 250 1.8E-71 T 06-07-2017 IPR006901 tRNA methyltransferase TrmK GO:0016429 GTHT12_RS12995 38497e98f55f8916c3195c5985b23c60 253 PIRSF PIRSF018637 23 253 2.0E-85 T 06-07-2017 IPR006901 tRNA methyltransferase TrmK GO:0016429 GTHT12_RS12995 38497e98f55f8916c3195c5985b23c60 253 SUPERFAMILY SSF53335 17 159 1.23E-10 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS12995 38497e98f55f8916c3195c5985b23c60 253 Gene3D G3DSA:3.40.50.150 29 172 1.1E-10 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS03855 35e67d53ca022a6a430f65dc475c3fec 56 Pfam PF09388 Spo0E like sporulation regulatory protein 5 41 2.1E-17 T 06-07-2017 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 GTHT12_RS03855 35e67d53ca022a6a430f65dc475c3fec 56 SUPERFAMILY SSF140500 3 44 2.35E-15 T 06-07-2017 GTHT12_RS11645 e2454afacf6e6ebb93697e3e5d970cf9 258 SUPERFAMILY SSF51366 7 250 5.06E-79 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 GTHT12_RS11645 e2454afacf6e6ebb93697e3e5d970cf9 258 Pfam PF00218 Indole-3-glycerol phosphate synthase 3 247 5.2E-87 T 06-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 GTHT12_RS11645 e2454afacf6e6ebb93697e3e5d970cf9 258 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 1 250 33.567 T 06-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 GTHT12_RS11645 e2454afacf6e6ebb93697e3e5d970cf9 258 Gene3D G3DSA:3.20.20.70 1 250 3.2E-94 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS11645 e2454afacf6e6ebb93697e3e5d970cf9 258 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 43 61 - T 06-07-2017 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 GTHT12_RS09255 aabb8cb4780dddc11cfc9e5b083d241e 205 Gene3D G3DSA:3.90.420.10 5 195 2.8E-37 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 GTHT12_RS09255 aabb8cb4780dddc11cfc9e5b083d241e 205 Pfam PF00174 Oxidoreductase molybdopterin binding domain 22 178 5.6E-25 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 GTHT12_RS09255 aabb8cb4780dddc11cfc9e5b083d241e 205 SUPERFAMILY SSF56524 5 196 7.98E-45 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 GTHT12_RS16895 130ac8aea06e8b4b1d6a274f27ef77b2 658 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 176 265 5.3E-17 T 06-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 GTHT12_RS16895 130ac8aea06e8b4b1d6a274f27ef77b2 658 SUPERFAMILY SSF52794 174 271 5.06E-31 T 06-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 GTHT12_RS16895 130ac8aea06e8b4b1d6a274f27ef77b2 658 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 13 157 8.2E-36 T 06-07-2017 IPR002178 PTS EIIA type-2 domain GTHT12_RS16895 130ac8aea06e8b4b1d6a274f27ef77b2 658 Gene3D G3DSA:3.40.50.2300 171 271 7.5E-37 T 06-07-2017 GTHT12_RS16895 130ac8aea06e8b4b1d6a274f27ef77b2 658 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 176 257 2.1E-25 T 06-07-2017 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 GTHT12_RS16895 130ac8aea06e8b4b1d6a274f27ef77b2 658 SUPERFAMILY SSF55804 9 157 5.49E-34 T 06-07-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 GTHT12_RS16895 130ac8aea06e8b4b1d6a274f27ef77b2 658 Pfam PF02378 Phosphotransferase system, EIIC 305 596 1.9E-12 T 06-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 GTHT12_RS16895 130ac8aea06e8b4b1d6a274f27ef77b2 658 Gene3D G3DSA:3.40.930.10 7 158 8.4E-44 T 06-07-2017 IPR002178 PTS EIIA type-2 domain GTHT12_RS16895 130ac8aea06e8b4b1d6a274f27ef77b2 658 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 15 140 3.0E-34 T 06-07-2017 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 GTHT12_RS16895 130ac8aea06e8b4b1d6a274f27ef77b2 658 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 297 647 4.0E-57 T 06-07-2017 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 GTHT12_RS04060 3a6b9bb56fad7847a19a3cdd6dc8a6c9 230 SMART SM00100 15 133 5.6E-23 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain GTHT12_RS04060 3a6b9bb56fad7847a19a3cdd6dc8a6c9 230 Pfam PF13545 Crp-like helix-turn-helix domain 157 226 6.8E-16 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 GTHT12_RS04060 3a6b9bb56fad7847a19a3cdd6dc8a6c9 230 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 178 194 3.6E-7 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 GTHT12_RS04060 3a6b9bb56fad7847a19a3cdd6dc8a6c9 230 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 194 209 3.6E-7 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 GTHT12_RS04060 3a6b9bb56fad7847a19a3cdd6dc8a6c9 230 SUPERFAMILY SSF51206 4 144 1.57E-37 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like GTHT12_RS04060 3a6b9bb56fad7847a19a3cdd6dc8a6c9 230 SUPERFAMILY SSF46785 152 229 1.43E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS04060 3a6b9bb56fad7847a19a3cdd6dc8a6c9 230 Gene3D G3DSA:1.10.10.10 150 228 3.6E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS04060 3a6b9bb56fad7847a19a3cdd6dc8a6c9 230 Gene3D G3DSA:2.60.120.10 10 146 2.3E-36 T 06-07-2017 IPR014710 RmlC-like jelly roll fold GTHT12_RS04060 3a6b9bb56fad7847a19a3cdd6dc8a6c9 230 SMART SM00419 170 220 8.2E-10 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 GTHT12_RS04060 3a6b9bb56fad7847a19a3cdd6dc8a6c9 230 ProSitePatterns PS00042 Crp-type HTH domain signature. 180 203 - T 06-07-2017 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 GTHT12_RS04060 3a6b9bb56fad7847a19a3cdd6dc8a6c9 230 Pfam PF00027 Cyclic nucleotide-binding domain 34 119 4.8E-20 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain GTHT12_RS05020 4f3ca3e0a86a150030b573fbc183abee 382 Gene3D G3DSA:3.40.50.2300 182 333 2.0E-24 T 06-07-2017 GTHT12_RS05020 4f3ca3e0a86a150030b573fbc183abee 382 Gene3D G3DSA:3.40.50.2300 64 181 2.9E-26 T 06-07-2017 GTHT12_RS05020 4f3ca3e0a86a150030b573fbc183abee 382 SUPERFAMILY SSF53822 66 344 6.23E-58 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS05020 4f3ca3e0a86a150030b573fbc183abee 382 Pfam PF13407 Periplasmic binding protein domain 77 327 1.9E-41 T 06-07-2017 IPR025997 Periplasmic binding protein GTHT12_RS12950 d7cade50ed2083b16fec8fe1fd3204b7 278 Gene3D G3DSA:1.10.3470.10 44 276 6.1E-13 T 06-07-2017 IPR029022 ABC transporter, BtuC-like GTHT12_RS12950 d7cade50ed2083b16fec8fe1fd3204b7 278 SUPERFAMILY SSF81345 5 269 2.48E-36 T 06-07-2017 IPR029022 ABC transporter, BtuC-like GTHT12_RS12950 d7cade50ed2083b16fec8fe1fd3204b7 278 Pfam PF00950 ABC 3 transport family 7 269 6.3E-64 T 06-07-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 GTHT12_RS04540 d17e0c249e9d3c0c2269f347a35f73bc 106 Pfam PF00085 Thioredoxin 6 101 5.2E-16 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 GTHT12_RS04540 d17e0c249e9d3c0c2269f347a35f73bc 106 Gene3D G3DSA:3.40.30.10 2 102 1.9E-20 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS04540 d17e0c249e9d3c0c2269f347a35f73bc 106 SUPERFAMILY SSF52833 3 104 3.53E-24 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS08745 ae9db6cfcd0e859f2444e2bf42bf0bfc 222 ProDom PD210561 YWRJ 1 221 2.0E-89 T 06-07-2017 IPR020173 Uncharacterised protein family YwrJ GTHT12_RS11225 1a19ceda26470af6dec8843a358bcacc 413 SUPERFAMILY SSF144052 5 409 1.83E-150 T 06-07-2017 GTHT12_RS11225 1a19ceda26470af6dec8843a358bcacc 413 Pfam PF02073 Thermophilic metalloprotease (M29) 5 408 4.9E-180 T 06-07-2017 IPR000787 Peptidase M29, aminopeptidase II GO:0004177|GO:0006508 GTHT12_RS11225 1a19ceda26470af6dec8843a358bcacc 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 245 264 9.8E-87 T 06-07-2017 IPR000787 Peptidase M29, aminopeptidase II GO:0004177|GO:0006508 GTHT12_RS11225 1a19ceda26470af6dec8843a358bcacc 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 301 321 9.8E-87 T 06-07-2017 IPR000787 Peptidase M29, aminopeptidase II GO:0004177|GO:0006508 GTHT12_RS11225 1a19ceda26470af6dec8843a358bcacc 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 389 408 9.8E-87 T 06-07-2017 IPR000787 Peptidase M29, aminopeptidase II GO:0004177|GO:0006508 GTHT12_RS11225 1a19ceda26470af6dec8843a358bcacc 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 324 345 9.8E-87 T 06-07-2017 IPR000787 Peptidase M29, aminopeptidase II GO:0004177|GO:0006508 GTHT12_RS11225 1a19ceda26470af6dec8843a358bcacc 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 80 99 9.8E-87 T 06-07-2017 IPR000787 Peptidase M29, aminopeptidase II GO:0004177|GO:0006508 GTHT12_RS11225 1a19ceda26470af6dec8843a358bcacc 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 15 32 9.8E-87 T 06-07-2017 IPR000787 Peptidase M29, aminopeptidase II GO:0004177|GO:0006508 GTHT12_RS11225 1a19ceda26470af6dec8843a358bcacc 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 363 385 9.8E-87 T 06-07-2017 IPR000787 Peptidase M29, aminopeptidase II GO:0004177|GO:0006508 GTHT12_RS11225 1a19ceda26470af6dec8843a358bcacc 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 156 178 9.8E-87 T 06-07-2017 IPR000787 Peptidase M29, aminopeptidase II GO:0004177|GO:0006508 GTHT12_RS09450 fe86c63386e9003f9990cfd2b7f1748b 258 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 2 248 8.0E-77 T 06-07-2017 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 GTHT12_RS09450 fe86c63386e9003f9990cfd2b7f1748b 258 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 2 240 3.4E-60 T 06-07-2017 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 GTHT12_RS09450 fe86c63386e9003f9990cfd2b7f1748b 258 Gene3D G3DSA:3.40.50.720 14 123 5.6E-4 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS08880 9b0d0f5137e0c727ad328deb2b16033b 354 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 108 5.8E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 GTHT12_RS08880 9b0d0f5137e0c727ad328deb2b16033b 354 PRINTS PR00111 Alpha/beta hydrolase fold signature 137 150 5.8E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 GTHT12_RS08880 9b0d0f5137e0c727ad328deb2b16033b 354 PRINTS PR00111 Alpha/beta hydrolase fold signature 151 164 5.8E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 GTHT12_RS08880 9b0d0f5137e0c727ad328deb2b16033b 354 Gene3D G3DSA:3.40.50.1820 42 352 1.8E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS08880 9b0d0f5137e0c727ad328deb2b16033b 354 SUPERFAMILY SSF53474 43 352 1.05E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS08880 9b0d0f5137e0c727ad328deb2b16033b 354 Pfam PF12697 Alpha/beta hydrolase family 70 342 9.6E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 GTHT12_RS18460 b84f29e4ed19855bcfcdb06bd4480d7d 212 Pfam PF02223 Thymidylate kinase 12 193 2.2E-22 T 06-07-2017 GTHT12_RS18460 b84f29e4ed19855bcfcdb06bd4480d7d 212 SUPERFAMILY SSF52540 4 187 1.11E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18460 b84f29e4ed19855bcfcdb06bd4480d7d 212 Gene3D G3DSA:3.40.50.300 4 205 3.7E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00245 4a9bb6c3e4fb5d40c86d05d3f56e14f0 290 Pfam PF00288 GHMP kinases N terminal domain 88 145 7.7E-13 T 06-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 GTHT12_RS00245 4a9bb6c3e4fb5d40c86d05d3f56e14f0 290 SUPERFAMILY SSF54211 3 159 2.28E-46 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS00245 4a9bb6c3e4fb5d40c86d05d3f56e14f0 290 Gene3D G3DSA:3.30.70.890 163 285 1.1E-37 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain GTHT12_RS00245 4a9bb6c3e4fb5d40c86d05d3f56e14f0 290 Gene3D G3DSA:3.30.230.10 4 159 2.7E-55 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GTHT12_RS00245 4a9bb6c3e4fb5d40c86d05d3f56e14f0 290 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 280 36.124 T 06-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 GTHT12_RS00245 4a9bb6c3e4fb5d40c86d05d3f56e14f0 290 SUPERFAMILY SSF55060 162 282 1.87E-34 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain GTHT12_RS00245 4a9bb6c3e4fb5d40c86d05d3f56e14f0 290 PIRSF PIRSF010376 1 289 2.5E-98 T 06-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 GTHT12_RS00245 4a9bb6c3e4fb5d40c86d05d3f56e14f0 290 Pfam PF08544 GHMP kinases C terminal 199 271 4.8E-10 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain GTHT12_RS00245 4a9bb6c3e4fb5d40c86d05d3f56e14f0 290 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 2 286 1.2E-108 T 06-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 GTHT12_RS08545 fac2daec90aa7b58dc6501339595f7c2 134 Gene3D G3DSA:3.10.129.10 6 131 8.6E-36 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS08545 fac2daec90aa7b58dc6501339595f7c2 134 PRINTS PR01483 Fatty acid synthase signature 23 45 3.4E-6 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 GTHT12_RS08545 fac2daec90aa7b58dc6501339595f7c2 134 PRINTS PR01483 Fatty acid synthase signature 45 66 3.4E-6 T 06-07-2017 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 GTHT12_RS08545 fac2daec90aa7b58dc6501339595f7c2 134 Pfam PF01575 MaoC like domain 17 117 1.4E-22 T 06-07-2017 IPR002539 MaoC-like domain GTHT12_RS08545 fac2daec90aa7b58dc6501339595f7c2 134 SUPERFAMILY SSF54637 4 131 1.75E-29 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS12155 7980f0d36af47f938cbb6de2c3b6f46e 335 PIRSF PIRSF011570 1 335 2.6E-168 T 06-07-2017 IPR010894 Stage V sporulation AD GTHT12_RS12155 7980f0d36af47f938cbb6de2c3b6f46e 335 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 6 332 8.0E-166 T 06-07-2017 IPR010894 Stage V sporulation AD GTHT12_RS12155 7980f0d36af47f938cbb6de2c3b6f46e 335 SUPERFAMILY SSF53901 56 312 2.11E-19 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS12155 7980f0d36af47f938cbb6de2c3b6f46e 335 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 5 332 2.2E-151 T 06-07-2017 IPR010894 Stage V sporulation AD GTHT12_RS12155 7980f0d36af47f938cbb6de2c3b6f46e 335 Gene3D G3DSA:3.40.47.10 56 175 3.7E-12 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS12795 4a3d2602f2ab7a79ce1397252df7c56b 80 ProDom PD059814 YQGY TRANSMEMBRANE MEMBRANE PRECURSOR BH2821 SIGNAL 1 79 8.0E-38 T 06-07-2017 IPR020254 Protein of unknown function DUF2626 GTHT12_RS12795 4a3d2602f2ab7a79ce1397252df7c56b 80 Pfam PF11117 Protein of unknown function (DUF2626) 1 74 1.7E-35 T 06-07-2017 IPR020254 Protein of unknown function DUF2626 GTHT12_RS17370 c9c858eff9c3c45e4a7fee7db0757dd9 534 SUPERFAMILY SSF56235 3 534 8.88E-186 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal GTHT12_RS17370 c9c858eff9c3c45e4a7fee7db0757dd9 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 377 395 5.5E-43 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GTHT12_RS17370 c9c858eff9c3c45e4a7fee7db0757dd9 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 233 249 5.5E-43 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GTHT12_RS17370 c9c858eff9c3c45e4a7fee7db0757dd9 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 408 423 5.5E-43 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GTHT12_RS17370 c9c858eff9c3c45e4a7fee7db0757dd9 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 42 67 5.5E-43 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GTHT12_RS17370 c9c858eff9c3c45e4a7fee7db0757dd9 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 129 148 5.5E-43 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GTHT12_RS17370 c9c858eff9c3c45e4a7fee7db0757dd9 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 111 129 5.5E-43 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GTHT12_RS17370 c9c858eff9c3c45e4a7fee7db0757dd9 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 262 281 5.5E-43 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GTHT12_RS17370 c9c858eff9c3c45e4a7fee7db0757dd9 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 432 449 5.5E-43 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GTHT12_RS17370 c9c858eff9c3c45e4a7fee7db0757dd9 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 353 371 5.5E-43 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GTHT12_RS17370 c9c858eff9c3c45e4a7fee7db0757dd9 534 Pfam PF01019 Gamma-glutamyltranspeptidase 35 529 2.0E-160 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 GTHT12_RS16720 bb7770e25aeaad6732f5c500a1333748 394 SUPERFAMILY SSF55031 187 294 2.22E-32 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS16720 bb7770e25aeaad6732f5c500a1333748 394 Gene3D G3DSA:3.40.630.10 301 392 5.5E-102 T 06-07-2017 GTHT12_RS16720 bb7770e25aeaad6732f5c500a1333748 394 Gene3D G3DSA:3.40.630.10 2 181 5.5E-102 T 06-07-2017 GTHT12_RS16720 bb7770e25aeaad6732f5c500a1333748 394 Pfam PF01546 Peptidase family M20/M25/M40 75 385 1.3E-34 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 GTHT12_RS16720 bb7770e25aeaad6732f5c500a1333748 394 SUPERFAMILY SSF53187 301 391 2.99E-86 T 06-07-2017 GTHT12_RS16720 bb7770e25aeaad6732f5c500a1333748 394 SUPERFAMILY SSF53187 4 200 2.99E-86 T 06-07-2017 GTHT12_RS16720 bb7770e25aeaad6732f5c500a1333748 394 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 18 378 2.5E-121 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 GTHT12_RS16720 bb7770e25aeaad6732f5c500a1333748 394 PIRSF PIRSF005962 1 394 7.5E-144 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 GTHT12_RS16720 bb7770e25aeaad6732f5c500a1333748 394 Gene3D G3DSA:3.30.70.360 184 300 1.4E-41 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS16720 bb7770e25aeaad6732f5c500a1333748 394 Pfam PF07687 Peptidase dimerisation domain 190 268 1.9E-8 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS11580 40c0242e0ce2b2d49b072ad6c07a38ca 199 Pfam PF07187 Protein of unknown function (DUF1405) 24 182 5.5E-60 T 06-07-2017 IPR009845 Protein of unknown function DUF1405 GTHT12_RS04160 3c9c23ea5409090590e658bba0190772 318 SUPERFAMILY SSF58104 33 311 3.79E-53 T 06-07-2017 GTHT12_RS04160 3c9c23ea5409090590e658bba0190772 318 SMART SM00283 48 313 1.4E-38 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 GTHT12_RS04160 3c9c23ea5409090590e658bba0190772 318 Gene3D G3DSA:1.10.287.950 72 286 1.1E-45 T 06-07-2017 GTHT12_RS04160 3c9c23ea5409090590e658bba0190772 318 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 121 312 1.0E-40 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 GTHT12_RS14570 dda03134d28e7abebe949af3e2a18805 919 Pfam PF00905 Penicillin binding protein transpeptidase domain 407 649 8.1E-30 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 GTHT12_RS14570 dda03134d28e7abebe949af3e2a18805 919 Gene3D G3DSA:2.60.40.10 822 886 3.1E-4 T 06-07-2017 IPR013783 Immunoglobulin-like fold GTHT12_RS14570 dda03134d28e7abebe949af3e2a18805 919 Gene3D G3DSA:3.40.710.10 273 741 5.5E-111 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS14570 dda03134d28e7abebe949af3e2a18805 919 SUPERFAMILY SSF53955 71 295 5.34E-67 T 06-07-2017 IPR023346 Lysozyme-like domain GTHT12_RS14570 dda03134d28e7abebe949af3e2a18805 919 Pfam PF00912 Transglycosylase 86 270 9.6E-58 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 GTHT12_RS14570 dda03134d28e7abebe949af3e2a18805 919 SUPERFAMILY SSF56601 256 274 2.82E-112 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS14570 dda03134d28e7abebe949af3e2a18805 919 SUPERFAMILY SSF56601 331 730 2.82E-112 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS14570 dda03134d28e7abebe949af3e2a18805 919 Gene3D G3DSA:1.10.3810.10 92 272 3.9E-66 T 06-07-2017 GTHT12_RS04110 d9b41d44e8e947d7a1216b6ad9b71318 557 Gene3D G3DSA:3.40.50.970 357 554 1.6E-80 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS04110 d9b41d44e8e947d7a1216b6ad9b71318 557 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 9 554 1.0E-194 T 06-07-2017 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 GTHT12_RS04110 d9b41d44e8e947d7a1216b6ad9b71318 557 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 171 1.0E-39 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 GTHT12_RS04110 d9b41d44e8e947d7a1216b6ad9b71318 557 SUPERFAMILY SSF52518 7 181 1.86E-39 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS04110 d9b41d44e8e947d7a1216b6ad9b71318 557 SUPERFAMILY SSF52467 186 354 1.15E-57 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS04110 d9b41d44e8e947d7a1216b6ad9b71318 557 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 326 8.8E-46 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 GTHT12_RS04110 d9b41d44e8e947d7a1216b6ad9b71318 557 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 385 531 9.7E-56 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 GTHT12_RS04110 d9b41d44e8e947d7a1216b6ad9b71318 557 SUPERFAMILY SSF52518 362 554 1.27E-74 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS04110 d9b41d44e8e947d7a1216b6ad9b71318 557 Gene3D G3DSA:3.40.50.970 9 176 4.0E-45 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS04110 d9b41d44e8e947d7a1216b6ad9b71318 557 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 422 441 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 GTHT12_RS04110 d9b41d44e8e947d7a1216b6ad9b71318 557 Gene3D G3DSA:3.40.50.1220 189 352 3.8E-62 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS05810 0b07cb627323be4f2f92e53e3d79ecc3 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 1.2E-29 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS05810 0b07cb627323be4f2f92e53e3d79ecc3 57 SUPERFAMILY SSF57829 1 55 1.04E-22 T 06-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 GTHT12_RS05810 0b07cb627323be4f2f92e53e3d79ecc3 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 20.46 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS05810 0b07cb627323be4f2f92e53e3d79ecc3 57 Pfam PF01783 Ribosomal L32p protein family 2 57 1.4E-27 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS06600 bfe1a60ec041fb335bba492d96c0e9cb 300 Gene3D G3DSA:3.40.50.720 1 138 8.2E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS06600 bfe1a60ec041fb335bba492d96c0e9cb 300 Gene3D G3DSA:3.40.50.720 139 269 1.3E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS06600 bfe1a60ec041fb335bba492d96c0e9cb 300 Pfam PF16924 Dipicolinate synthase subunit A N-terminal domain 7 124 2.3E-29 T 06-07-2017 IPR031629 Dipicolinate synthase subunit A, N-terminal GTHT12_RS06600 bfe1a60ec041fb335bba492d96c0e9cb 300 SUPERFAMILY SSF51735 132 270 1.69E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS06600 bfe1a60ec041fb335bba492d96c0e9cb 300 TIGRFAM TIGR02853 spore_dpaA: dipicolinic acid synthetase, A subunit 5 290 1.8E-137 T 06-07-2017 IPR014215 Dipicolinic acid synthetase subunit A GTHT12_RS06600 bfe1a60ec041fb335bba492d96c0e9cb 300 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 144 291 2.2E-10 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain GTHT12_RS07810 3a2ac1e59a0f1d405b0331bea3b55f43 61 Gene3D G3DSA:1.20.1260.10 7 60 6.5E-5 T 06-07-2017 IPR012347 Ferritin-related GTHT12_RS16980 0e6e035252c5a42cc925865c2c0919fe 401 SUPERFAMILY SSF53756 4 399 1.05E-45 T 06-07-2017 GTHT12_RS16980 0e6e035252c5a42cc925865c2c0919fe 401 Pfam PF00534 Glycosyl transferases group 1 220 375 7.6E-12 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 GTHT12_RS16980 0e6e035252c5a42cc925865c2c0919fe 401 Pfam PF13579 Glycosyl transferase 4-like domain 20 204 2.6E-15 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 GTHT12_RS13090 e70478c7c84657fae3b44f0165adc75c 311 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 10 300 8.9E-71 T 06-07-2017 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 GTHT12_RS13090 e70478c7c84657fae3b44f0165adc75c 311 Pfam PF02690 Na+/Pi-cotransporter 15 149 3.0E-36 T 06-07-2017 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 GTHT12_RS13090 e70478c7c84657fae3b44f0165adc75c 311 Pfam PF02690 Na+/Pi-cotransporter 162 257 4.7E-18 T 06-07-2017 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 GTHT12_RS05065 84f38aebd2b163b277c71da558d404b2 243 Pfam PF02535 ZIP Zinc transporter 91 239 1.5E-14 T 06-07-2017 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 GTHT12_RS16680 fe4a439e7e10809c2dd7a68412832bbe 150 Pfam PF04892 VanZ like family 8 135 2.8E-20 T 06-07-2017 IPR006976 VanZ-like GTHT12_RS16680 fe4a439e7e10809c2dd7a68412832bbe 150 PIRSF PIRSF019083 2 149 1.2E-39 T 06-07-2017 IPR016747 Phosphotransbutyrylase GTHT12_RS07625 2d869dbdade81158d15b77a1a822e634 326 SUPERFAMILY SSF52540 36 248 1.28E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07625 2d869dbdade81158d15b77a1a822e634 326 Gene3D G3DSA:3.40.50.300 2 257 2.2E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07625 2d869dbdade81158d15b77a1a822e634 326 Pfam PF00005 ABC transporter 39 183 2.7E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS07625 2d869dbdade81158d15b77a1a822e634 326 SMART SM00382 48 232 2.7E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS07670 ba8722e423dab0a3f617e9ce75912a93 134 Pfam PF04134 Protein of unknown function, DUF393 5 112 8.9E-25 T 06-07-2017 IPR007263 Protein of unknown function DUF393 GTHT12_RS12380 46e5a1170b76491566ac1df592fbbb3b 327 Pfam PF06081 Aromatic acid exporter family member 1 1 141 1.0E-54 T 06-07-2017 IPR010343 Aromatic acid exporter family member 1 GTHT12_RS12380 46e5a1170b76491566ac1df592fbbb3b 327 Pfam PF11728 Putative aromatic acid exporter C-terminal domain 145 309 1.9E-56 T 06-07-2017 IPR021062 Putative aromatic acid exporter, C-terminal GTHT12_RS10580 e18aa4f8acc1e7cc48eb406b28093cf7 383 Pfam PF10720 Protein of unknown function (DUF2515) 46 374 7.7E-127 T 06-07-2017 IPR019658 Protein of unknown function DUF2515 GTHT12_RS07330 1f4919877fff75be096eba5883cb077d 487 SUPERFAMILY SSF53720 8 486 8.38E-167 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GTHT12_RS07330 1f4919877fff75be096eba5883cb077d 487 Pfam PF00171 Aldehyde dehydrogenase family 17 483 1.5E-175 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS07330 1f4919877fff75be096eba5883cb077d 487 Gene3D G3DSA:3.40.605.10 11 267 1.3E-98 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS07330 1f4919877fff75be096eba5883cb077d 487 Gene3D G3DSA:3.40.309.10 268 457 1.0E-71 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 GTHT12_RS07330 1f4919877fff75be096eba5883cb077d 487 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 GTHT12_RS07330 1f4919877fff75be096eba5883cb077d 487 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 281 292 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 GTHT12_RS06410 e1b972d68f68f5bf3af677800796f037 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 4.1E-24 T 06-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 GTHT12_RS06410 e1b972d68f68f5bf3af677800796f037 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 4.1E-24 T 06-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 GTHT12_RS06410 e1b972d68f68f5bf3af677800796f037 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 4.1E-24 T 06-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 GTHT12_RS06410 e1b972d68f68f5bf3af677800796f037 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 5.4E-32 T 06-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 GTHT12_RS06410 e1b972d68f68f5bf3af677800796f037 89 PIRSF PIRSF004669 1 89 9.9E-35 T 06-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 GTHT12_RS06410 e1b972d68f68f5bf3af677800796f037 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 1.8E-34 T 06-07-2017 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 GTHT12_RS04935 9186429627ec994b95b07c6ec7e85fd9 511 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 434 6.6E-92 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 GTHT12_RS04935 9186429627ec994b95b07c6ec7e85fd9 511 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 148 173 - T 06-07-2017 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 GTHT12_RS04935 9186429627ec994b95b07c6ec7e85fd9 511 Pfam PF00474 Sodium:solute symporter family 33 434 5.9E-126 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 GTHT12_RS04935 9186429627ec994b95b07c6ec7e85fd9 511 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 416 436 - T 06-07-2017 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 GTHT12_RS11530 2b4a192b73dd8962f2b18d543ad40243 279 PIRSF PIRSF000388 1 266 1.3E-113 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 GTHT12_RS11530 2b4a192b73dd8962f2b18d543ad40243 279 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 2 263 44.074 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 GTHT12_RS11530 2b4a192b73dd8962f2b18d543ad40243 279 Gene3D G3DSA:3.20.20.60 3 263 1.7E-119 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GTHT12_RS11530 2b4a192b73dd8962f2b18d543ad40243 279 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 2 263 7.7E-119 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 GTHT12_RS11530 2b4a192b73dd8962f2b18d543ad40243 279 SUPERFAMILY SSF51621 3 263 4.71E-109 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GTHT12_RS11530 2b4a192b73dd8962f2b18d543ad40243 279 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 258 9.0E-116 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 GTHT12_RS03315 2ddac5d8df3306442281a29731507110 385 SUPERFAMILY SSF53300 212 347 2.72E-5 T 06-07-2017 IPR002035 von Willebrand factor, type A GTHT12_RS03315 2ddac5d8df3306442281a29731507110 385 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 3 381 32.051 T 06-07-2017 IPR006698 Uncharacterised protein family UPF0229 GTHT12_RS03315 2ddac5d8df3306442281a29731507110 385 Pfam PF04285 Protein of unknown function (DUF444) 11 181 2.9E-34 T 06-07-2017 IPR006698 Uncharacterised protein family UPF0229 GTHT12_RS03315 2ddac5d8df3306442281a29731507110 385 Pfam PF04285 Protein of unknown function (DUF444) 188 379 1.7E-69 T 06-07-2017 IPR006698 Uncharacterised protein family UPF0229 GTHT12_RS03315 2ddac5d8df3306442281a29731507110 385 TIGRFAM TIGR02877 spore_yhbH: sporulation protein YhbH 5 376 6.0E-183 T 06-07-2017 IPR014230 Sporulation protein YhbH GTHT12_RS11895 c54a9c4e710ad209474a0ce17c2d726f 82 Gene3D G3DSA:3.30.70.20 4 80 1.4E-30 T 06-07-2017 GTHT12_RS11895 c54a9c4e710ad209474a0ce17c2d726f 82 SUPERFAMILY SSF54862 3 73 4.19E-13 T 06-07-2017 GTHT12_RS11895 c54a9c4e710ad209474a0ce17c2d726f 82 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 69 6.6E-23 T 06-07-2017 GTHT12_RS11895 c54a9c4e710ad209474a0ce17c2d726f 82 PRINTS PR00352 3Fe-4S ferredoxin signature 55 67 7.3E-8 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 GTHT12_RS11895 c54a9c4e710ad209474a0ce17c2d726f 82 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 7.3E-8 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 GTHT12_RS11895 c54a9c4e710ad209474a0ce17c2d726f 82 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 7.3E-8 T 06-07-2017 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 GTHT12_RS09520 dfedca703155cc42f1a64743f7309c4b 616 Gene3D G3DSA:3.40.390.10 359 435 3.1E-6 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 GTHT12_RS09520 dfedca703155cc42f1a64743f7309c4b 616 SUPERFAMILY SSF55486 23 591 7.08E-115 T 06-07-2017 GTHT12_RS09520 dfedca703155cc42f1a64743f7309c4b 616 Gene3D G3DSA:1.10.287.830 201 236 7.1E-7 T 06-07-2017 GTHT12_RS09520 dfedca703155cc42f1a64743f7309c4b 616 Pfam PF08439 Oligopeptidase F 126 190 2.6E-17 T 06-07-2017 IPR013647 Oligopeptidase F, N-terminal domain GTHT12_RS09520 dfedca703155cc42f1a64743f7309c4b 616 Pfam PF01432 Peptidase family M3 215 594 1.2E-66 T 06-07-2017 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 GTHT12_RS09520 dfedca703155cc42f1a64743f7309c4b 616 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 23 607 2.6E-177 T 06-07-2017 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 GTHT12_RS15970 f350fbc48f9fd128a01a36f7e97a72e3 215 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 27 99 3.5E-36 T 06-07-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 GTHT12_RS15970 f350fbc48f9fd128a01a36f7e97a72e3 215 SUPERFAMILY SSF141734 5 107 1.1E-49 T 06-07-2017 GTHT12_RS15970 f350fbc48f9fd128a01a36f7e97a72e3 215 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 1 104 31.671 T 06-07-2017 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 GTHT12_RS15970 f350fbc48f9fd128a01a36f7e97a72e3 215 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 118 201 1.7E-32 T 06-07-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 GTHT12_RS15970 f350fbc48f9fd128a01a36f7e97a72e3 215 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 50 99 1.0E-24 T 06-07-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 GTHT12_RS15970 f350fbc48f9fd128a01a36f7e97a72e3 215 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 3 206 39.296 T 06-07-2017 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 GTHT12_RS15970 f350fbc48f9fd128a01a36f7e97a72e3 215 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 115 201 20.854 T 06-07-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 GTHT12_RS15970 f350fbc48f9fd128a01a36f7e97a72e3 215 SUPERFAMILY SSF101386 117 205 8.78E-27 T 06-07-2017 GTHT12_RS15970 f350fbc48f9fd128a01a36f7e97a72e3 215 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 118 204 2.2E-18 T 06-07-2017 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 GTHT12_RS04450 39302a56a708f10da912bfc7b97426c7 387 Pfam PF13439 Glycosyltransferase Family 4 32 166 1.7E-16 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 GTHT12_RS04450 39302a56a708f10da912bfc7b97426c7 387 SUPERFAMILY SSF53756 2 374 2.34E-74 T 06-07-2017 GTHT12_RS04450 39302a56a708f10da912bfc7b97426c7 387 Pfam PF00534 Glycosyl transferases group 1 182 354 3.5E-43 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 GTHT12_RS04450 39302a56a708f10da912bfc7b97426c7 387 Gene3D G3DSA:3.40.50.2000 148 354 1.5E-32 T 06-07-2017 GTHT12_RS06150 22fe16d1153185a7823b72f4b5baee15 556 SUPERFAMILY SSF101473 3 202 1.44E-47 T 06-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 GTHT12_RS06150 22fe16d1153185a7823b72f4b5baee15 556 SMART SM01121 239 556 3.6E-193 T 06-07-2017 IPR033470 Uncharacterised protein, DhaK domain GTHT12_RS06150 22fe16d1153185a7823b72f4b5baee15 556 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 11 556 2.9E-217 T 06-07-2017 IPR019986 DAK2 domain-containing protein YloV GTHT12_RS06150 22fe16d1153185a7823b72f4b5baee15 556 Pfam PF13684 Dihydroxyacetone kinase family 239 556 5.8E-126 T 06-07-2017 IPR033470 Uncharacterised protein, DhaK domain GTHT12_RS06150 22fe16d1153185a7823b72f4b5baee15 556 Pfam PF02734 DAK2 domain 36 200 7.0E-43 T 06-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 GTHT12_RS06150 22fe16d1153185a7823b72f4b5baee15 556 SMART SM01120 36 201 7.2E-74 T 06-07-2017 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 GTHT12_RS04890 edf9c1738770372479d41ba5a1c3b1eb 327 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 2 318 6.2E-75 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 GTHT12_RS04890 edf9c1738770372479d41ba5a1c3b1eb 327 PIRSF PIRSF001439 1 327 5.2E-89 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 GTHT12_RS04890 edf9c1738770372479d41ba5a1c3b1eb 327 Gene3D G3DSA:3.30.1780.10 1 135 6.2E-45 T 06-07-2017 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 GTHT12_RS04890 edf9c1738770372479d41ba5a1c3b1eb 327 Gene3D G3DSA:3.40.50.720 136 300 4.5E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS04890 edf9c1738770372479d41ba5a1c3b1eb 327 SUPERFAMILY SSF51735 1 327 9.37E-98 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS15290 106b55ce004f3326a7a32c20d18b62d5 77 Pfam PF04070 Domain of unknown function (DUF378) 3 61 1.1E-27 T 06-07-2017 IPR007211 Protein of unknown function DUF378 GTHT12_RS13340 3ecd5d400d4ee515500dbc11fe709741 423 SUPERFAMILY SSF51366 32 178 3.25E-5 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 GTHT12_RS13340 3ecd5d400d4ee515500dbc11fe709741 423 ProSitePatterns PS01276 Peptidase family U32 signature. 179 197 - T 06-07-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 GTHT12_RS13340 3ecd5d400d4ee515500dbc11fe709741 423 Gene3D G3DSA:3.20.20.70 50 126 2.5E-4 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS13340 3ecd5d400d4ee515500dbc11fe709741 423 Pfam PF16325 Peptidase family U32 C-terminal domain 339 420 2.1E-26 T 06-07-2017 IPR032525 Peptidase family U32, C-terminal GTHT12_RS13340 3ecd5d400d4ee515500dbc11fe709741 423 Pfam PF01136 Peptidase family U32 95 323 2.6E-88 T 06-07-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 GTHT12_RS09920 5d8da80d37cb14892d817028aa6a59df 440 Gene3D G3DSA:3.40.190.10 161 339 7.4E-32 T 06-07-2017 GTHT12_RS09920 5d8da80d37cb14892d817028aa6a59df 440 Pfam PF01547 Bacterial extracellular solute-binding protein 51 351 1.8E-34 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 GTHT12_RS09920 5d8da80d37cb14892d817028aa6a59df 440 SUPERFAMILY SSF53850 21 437 6.92E-82 T 06-07-2017 GTHT12_RS09920 5d8da80d37cb14892d817028aa6a59df 440 Gene3D G3DSA:3.40.190.10 340 368 2.6E-31 T 06-07-2017 GTHT12_RS09920 5d8da80d37cb14892d817028aa6a59df 440 Gene3D G3DSA:3.40.190.10 38 157 2.6E-31 T 06-07-2017 GTHT12_RS06165 b699e93adabdbb3fb658949bcedf1e0d 682 SMART SM00490 488 573 2.1E-21 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS06165 b699e93adabdbb3fb658949bcedf1e0d 682 Gene3D G3DSA:3.40.50.300 439 621 1.0E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06165 b699e93adabdbb3fb658949bcedf1e0d 682 SUPERFAMILY SSF50249 7 167 5.31E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS06165 b699e93adabdbb3fb658949bcedf1e0d 682 SMART SM00487 253 443 4.0E-34 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain GTHT12_RS06165 b699e93adabdbb3fb658949bcedf1e0d 682 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 26 648 1.6E-242 T 06-07-2017 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 GTHT12_RS06165 b699e93adabdbb3fb658949bcedf1e0d 682 Gene3D G3DSA:3.40.50.300 242 438 6.1E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06165 b699e93adabdbb3fb658949bcedf1e0d 682 Gene3D G3DSA:2.40.50.140 47 123 1.3E-12 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS06165 b699e93adabdbb3fb658949bcedf1e0d 682 SUPERFAMILY SSF52540 173 436 1.73E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06165 b699e93adabdbb3fb658949bcedf1e0d 682 Gene3D G3DSA:1.10.150.20 7 40 8.3E-6 T 06-07-2017 GTHT12_RS06165 b699e93adabdbb3fb658949bcedf1e0d 682 Pfam PF17191 RecG wedge domain 10 163 5.6E-14 T 06-07-2017 IPR033454 RecG, wedge domain GTHT12_RS06165 b699e93adabdbb3fb658949bcedf1e0d 682 Pfam PF00271 Helicase conserved C-terminal domain 454 572 7.8E-21 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS06165 b699e93adabdbb3fb658949bcedf1e0d 682 SUPERFAMILY SSF52540 376 585 7.64E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06165 b699e93adabdbb3fb658949bcedf1e0d 682 Pfam PF00270 DEAD/DEAH box helicase 258 417 3.6E-19 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 GTHT12_RS17605 932c91bd95d9b0c758af6f41b3d54bc7 213 ProSitePatterns PS00958 Transaldolase active site. 80 97 - T 06-07-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 GTHT12_RS17605 932c91bd95d9b0c758af6f41b3d54bc7 213 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 211 3.4E-105 T 06-07-2017 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 GTHT12_RS17605 932c91bd95d9b0c758af6f41b3d54bc7 213 Gene3D G3DSA:3.20.20.70 1 211 3.6E-73 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS17605 932c91bd95d9b0c758af6f41b3d54bc7 213 Hamap MF_00494 Probable transaldolase [tal]. 1 213 46.99 T 06-07-2017 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 GTHT12_RS17605 932c91bd95d9b0c758af6f41b3d54bc7 213 Pfam PF00923 Transaldolase 3 204 8.5E-57 T 06-07-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 GTHT12_RS17605 932c91bd95d9b0c758af6f41b3d54bc7 213 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 06-07-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 GTHT12_RS17605 932c91bd95d9b0c758af6f41b3d54bc7 213 SUPERFAMILY SSF51569 1 211 8.58E-79 T 06-07-2017 GTHT12_RS13000 47fa22510cc9a0a32ca214dc22edc85c 120 PIRSF PIRSF000025 1 120 1.3E-34 T 06-07-2017 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 GTHT12_RS13000 47fa22510cc9a0a32ca214dc22edc85c 120 Gene3D G3DSA:1.10.760.10 52 119 4.2E-21 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GTHT12_RS13000 47fa22510cc9a0a32ca214dc22edc85c 120 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 53 116 2.3E-12 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GTHT12_RS13000 47fa22510cc9a0a32ca214dc22edc85c 120 SUPERFAMILY SSF46626 6 119 3.44E-17 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GTHT12_RS10045 bcc68ca08a75f4d61da14a130b81cc81 336 SUPERFAMILY SSF53613 11 324 1.56E-81 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS10045 bcc68ca08a75f4d61da14a130b81cc81 336 Gene3D G3DSA:3.40.1190.20 6 330 4.9E-93 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS10045 bcc68ca08a75f4d61da14a130b81cc81 336 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 12 324 7.8E-131 T 06-07-2017 IPR030830 5-dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 GTHT12_RS10045 bcc68ca08a75f4d61da14a130b81cc81 336 Pfam PF00294 pfkB family carbohydrate kinase 16 316 1.9E-64 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB GTHT12_RS10045 bcc68ca08a75f4d61da14a130b81cc81 336 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 268 281 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 GTHT12_RS10045 bcc68ca08a75f4d61da14a130b81cc81 336 Hamap MF_01668 5-dehydro-2-deoxygluconokinase [iolC]. 8 328 54.552 T 06-07-2017 IPR022841 5-dehydro-2-deoxygluconokinase, Firmicutes GO:0016310|GO:0047590 KEGG: 00562+2.7.1.92 GTHT12_RS16165 07b47a8e2fcc1ef405acf145931f55ae 344 SMART SM00506 1 132 1.8E-27 T 06-07-2017 IPR002589 Macro domain GTHT12_RS16165 07b47a8e2fcc1ef405acf145931f55ae 344 Pfam PF01661 Macro domain 18 129 3.8E-25 T 06-07-2017 IPR002589 Macro domain GTHT12_RS16165 07b47a8e2fcc1ef405acf145931f55ae 344 SUPERFAMILY SSF52949 1 148 8.58E-45 T 06-07-2017 GTHT12_RS16165 07b47a8e2fcc1ef405acf145931f55ae 344 Gene3D G3DSA:3.40.220.10 2 138 9.8E-14 T 06-07-2017 GTHT12_RS05975 63695ff052530bafa8575b25deb43139 154 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 150 16.693 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 GTHT12_RS05975 63695ff052530bafa8575b25deb43139 154 Pfam PF01252 Signal peptidase (SPase) II 7 145 2.7E-38 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 GTHT12_RS05975 63695ff052530bafa8575b25deb43139 154 TIGRFAM TIGR00077 lspA: signal peptidase II 2 148 1.9E-47 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 GTHT12_RS05975 63695ff052530bafa8575b25deb43139 154 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 89 104 4.3E-18 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 GTHT12_RS05975 63695ff052530bafa8575b25deb43139 154 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 45 53 4.3E-18 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 GTHT12_RS05975 63695ff052530bafa8575b25deb43139 154 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 125 141 4.3E-18 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 GTHT12_RS05975 63695ff052530bafa8575b25deb43139 154 ProSitePatterns PS00855 Signal peptidases II signature. 92 104 - T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 GTHT12_RS00090 c3485cc7af0ec86e76f4f77c9de6c38f 424 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 3.4E-32 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 GTHT12_RS00090 c3485cc7af0ec86e76f4f77c9de6c38f 424 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 3.4E-32 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 GTHT12_RS00090 c3485cc7af0ec86e76f4f77c9de6c38f 424 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 3.4E-32 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 GTHT12_RS00090 c3485cc7af0ec86e76f4f77c9de6c38f 424 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 3.4E-32 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 GTHT12_RS00090 c3485cc7af0ec86e76f4f77c9de6c38f 424 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 3.4E-32 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 GTHT12_RS00090 c3485cc7af0ec86e76f4f77c9de6c38f 424 PIRSF PIRSF001529 1 424 5.1E-194 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 GTHT12_RS00090 c3485cc7af0ec86e76f4f77c9de6c38f 424 Gene3D G3DSA:1.10.287.40 1 105 3.0E-25 T 06-07-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 GTHT12_RS00090 c3485cc7af0ec86e76f4f77c9de6c38f 424 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 222 400 5.3E-39 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS00090 c3485cc7af0ec86e76f4f77c9de6c38f 424 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 417 5.2E-183 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 GTHT12_RS00090 c3485cc7af0ec86e76f4f77c9de6c38f 424 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 44.86 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 GTHT12_RS00090 c3485cc7af0ec86e76f4f77c9de6c38f 424 SUPERFAMILY SSF55681 117 420 2.19E-108 T 06-07-2017 GTHT12_RS00090 c3485cc7af0ec86e76f4f77c9de6c38f 424 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 2.6E-32 T 06-07-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 GTHT12_RS00090 c3485cc7af0ec86e76f4f77c9de6c38f 424 Gene3D G3DSA:3.30.930.10 106 420 1.6E-145 T 06-07-2017 GTHT12_RS00090 c3485cc7af0ec86e76f4f77c9de6c38f 424 SUPERFAMILY SSF46589 1 113 5.23E-32 T 06-07-2017 IPR010978 tRNA-binding arm GO:0000166 GTHT12_RS04900 1017345e47693b43e19f0faf20b40ab9 308 Pfam PF00781 Diacylglycerol kinase catalytic domain 3 126 1.3E-29 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 GTHT12_RS04900 1017345e47693b43e19f0faf20b40ab9 308 SUPERFAMILY SSF111331 1 303 6.98E-76 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain GTHT12_RS04900 1017345e47693b43e19f0faf20b40ab9 308 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 4 288 6.1E-49 T 06-07-2017 IPR005218 Diacylglycerol/lipid kinase GTHT12_RS04900 1017345e47693b43e19f0faf20b40ab9 308 SMART SM00046 2 127 0.001 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 GTHT12_RS11550 9f0d8290c5052e99c35ebc734a5e1974 236 SUPERFAMILY SSF102588 6 232 3.53E-59 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 GTHT12_RS11550 9f0d8290c5052e99c35ebc734a5e1974 236 TIGRFAM TIGR04001 thiol_BshB1: bacillithiol biosynthesis deacetylase BshB1 5 228 6.2E-102 T 06-07-2017 IPR023842 Bacillithiol biosynthesis deacetylase, BshB1 GO:0019213|GO:0071793 GTHT12_RS11550 9f0d8290c5052e99c35ebc734a5e1974 236 Gene3D G3DSA:3.40.50.10320 6 226 2.0E-65 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 GTHT12_RS11550 9f0d8290c5052e99c35ebc734a5e1974 236 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 124 2.6E-23 T 06-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 GTHT12_RS17230 11b6803eaa3f95a90f950fbc038d7032 266 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 66 235 6.6E-61 T 06-07-2017 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 GTHT12_RS17230 11b6803eaa3f95a90f950fbc038d7032 266 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 61 239 1.8E-57 T 06-07-2017 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 GTHT12_RS04120 d4bf4c4696afeee1c7097c063506b7e9 1227 Gene3D G3DSA:2.40.40.20 1044 1220 1.0E-38 T 06-07-2017 GTHT12_RS04120 d4bf4c4696afeee1c7097c063506b7e9 1227 Gene3D G3DSA:3.40.50.740 641 821 9.9E-65 T 06-07-2017 GTHT12_RS04120 d4bf4c4696afeee1c7097c063506b7e9 1227 Gene3D G3DSA:3.40.50.740 110 225 9.9E-65 T 06-07-2017 GTHT12_RS04120 d4bf4c4696afeee1c7097c063506b7e9 1227 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 50 68 - T 06-07-2017 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 GTHT12_RS04120 d4bf4c4696afeee1c7097c063506b7e9 1227 SMART SM00926 45 107 4.7E-9 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS04120 d4bf4c4696afeee1c7097c063506b7e9 1227 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 7 1226 0.0 T 06-07-2017 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 GTHT12_RS04120 d4bf4c4696afeee1c7097c063506b7e9 1227 Pfam PF00384 Molybdopterin oxidoreductase 110 819 1.6E-156 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS04120 d4bf4c4696afeee1c7097c063506b7e9 1227 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 1114 1141 - T 06-07-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 GTHT12_RS04120 d4bf4c4696afeee1c7097c063506b7e9 1227 Gene3D G3DSA:2.20.25.90 54 100 2.5E-30 T 06-07-2017 GTHT12_RS04120 d4bf4c4696afeee1c7097c063506b7e9 1227 Pfam PF01568 Molydopterin dinucleotide binding domain 1076 1188 5.2E-21 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 GTHT12_RS04120 d4bf4c4696afeee1c7097c063506b7e9 1227 SUPERFAMILY SSF53706 25 1054 0.0 T 06-07-2017 GTHT12_RS04120 d4bf4c4696afeee1c7097c063506b7e9 1227 SUPERFAMILY SSF50692 1071 1221 8.14E-46 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain GTHT12_RS04120 d4bf4c4696afeee1c7097c063506b7e9 1227 Gene3D G3DSA:3.40.228.10 226 339 5.8E-87 T 06-07-2017 GTHT12_RS04120 d4bf4c4696afeee1c7097c063506b7e9 1227 Gene3D G3DSA:3.40.228.10 483 606 5.8E-87 T 06-07-2017 GTHT12_RS12150 ed542e359cbf8e09ba0a78c961eb8157 117 Pfam PF03862 SpoVA protein 3 112 3.9E-27 T 06-07-2017 IPR005562 SpoVA GTHT12_RS16290 f84f731a05e7489372bbcf3edd6f3c0e 225 Gene3D G3DSA:3.40.50.2300 2 120 9.1E-40 T 06-07-2017 GTHT12_RS16290 f84f731a05e7489372bbcf3edd6f3c0e 225 Pfam PF00072 Response regulator receiver domain 5 117 4.4E-33 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS16290 f84f731a05e7489372bbcf3edd6f3c0e 225 ProSitePatterns PS00622 LuxR-type HTH domain signature. 176 203 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS16290 f84f731a05e7489372bbcf3edd6f3c0e 225 SMART SM00448 3 116 1.5E-33 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS16290 f84f731a05e7489372bbcf3edd6f3c0e 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 1.5E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS16290 f84f731a05e7489372bbcf3edd6f3c0e 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 1.5E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS16290 f84f731a05e7489372bbcf3edd6f3c0e 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 1.5E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS16290 f84f731a05e7489372bbcf3edd6f3c0e 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 216 3.0E-22 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS16290 f84f731a05e7489372bbcf3edd6f3c0e 225 SUPERFAMILY SSF46894 149 223 1.02E-24 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GTHT12_RS16290 f84f731a05e7489372bbcf3edd6f3c0e 225 SMART SM00421 159 216 2.1E-28 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS16290 f84f731a05e7489372bbcf3edd6f3c0e 225 SUPERFAMILY SSF52172 2 134 3.13E-38 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS16290 f84f731a05e7489372bbcf3edd6f3c0e 225 Gene3D G3DSA:1.10.10.10 121 223 1.8E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS06965 418433aaf9152fc8d035c6b6b19c0aa4 245 Hamap MF_01246 Chitooligosaccharide deacetylase [chbG]. 3 239 42.163 T 06-07-2017 IPR022948 Chitooligosaccharide deacetylase ChbG-like, bacteria GO:0000272|GO:0016811 GTHT12_RS06965 418433aaf9152fc8d035c6b6b19c0aa4 245 SUPERFAMILY SSF88713 1 242 3.33E-83 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 GTHT12_RS06965 418433aaf9152fc8d035c6b6b19c0aa4 245 Gene3D G3DSA:3.20.20.370 2 242 5.7E-90 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 GTHT12_RS06965 418433aaf9152fc8d035c6b6b19c0aa4 245 Pfam PF04794 YdjC-like protein 6 230 2.4E-65 T 06-07-2017 IPR006879 Chitooligosaccharide deacetylase ChbG-like GTHT12_RS08535 04aa8962fbb258932c6cfc7d31fc55aa 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.3E-49 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08535 04aa8962fbb258932c6cfc7d31fc55aa 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 4.3E-49 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08535 04aa8962fbb258932c6cfc7d31fc55aa 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 4.3E-49 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08535 04aa8962fbb258932c6cfc7d31fc55aa 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 4.3E-49 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08535 04aa8962fbb258932c6cfc7d31fc55aa 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.3E-49 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08535 04aa8962fbb258932c6cfc7d31fc55aa 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 4.3E-49 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08535 04aa8962fbb258932c6cfc7d31fc55aa 254 SUPERFAMILY SSF51735 7 251 2.21E-88 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS08535 04aa8962fbb258932c6cfc7d31fc55aa 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 251 1.9E-67 T 06-07-2017 GTHT12_RS08535 04aa8962fbb258932c6cfc7d31fc55aa 254 Gene3D G3DSA:3.40.50.720 1 251 1.2E-92 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS08535 04aa8962fbb258932c6cfc7d31fc55aa 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.4E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08535 04aa8962fbb258932c6cfc7d31fc55aa 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.4E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08535 04aa8962fbb258932c6cfc7d31fc55aa 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.4E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08535 04aa8962fbb258932c6cfc7d31fc55aa 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 186 3.2E-5 T 06-07-2017 GTHT12_RS08535 04aa8962fbb258932c6cfc7d31fc55aa 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GTHT12_RS07970 b4e91ae8edb93fd61ba024ca1a97d536 53 Pfam PF08113 Cytochrome c oxidase subunit IIa family 26 52 1.1E-4 T 06-07-2017 IPR012538 Cytochrome c oxidase polypeptide 2A KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 GTHT12_RS02230 aab12a71eb839baa400d2bf21dfadb3f 552 Pfam PF00196 Bacterial regulatory proteins, luxR family 482 536 1.1E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS02230 aab12a71eb839baa400d2bf21dfadb3f 552 SMART SM00421 480 537 5.4E-25 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS02230 aab12a71eb839baa400d2bf21dfadb3f 552 Gene3D G3DSA:1.10.10.10 480 539 3.9E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS02230 aab12a71eb839baa400d2bf21dfadb3f 552 ProSitePatterns PS00622 LuxR-type HTH domain signature. 497 524 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS02230 aab12a71eb839baa400d2bf21dfadb3f 552 SUPERFAMILY SSF46894 476 541 1.56E-21 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GTHT12_RS02230 aab12a71eb839baa400d2bf21dfadb3f 552 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 483 497 4.5E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS02230 aab12a71eb839baa400d2bf21dfadb3f 552 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 513 525 4.5E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS02230 aab12a71eb839baa400d2bf21dfadb3f 552 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 497 513 4.5E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS02230 aab12a71eb839baa400d2bf21dfadb3f 552 Pfam PF10114 Sensory domain found in PocR 6 121 1.7E-12 T 06-07-2017 IPR018771 PocR domain GTHT12_RS04375 2bf0f2202f8af284d782daed098957d5 137 Pfam PF01152 Bacterial-like globin 7 123 2.8E-34 T 06-07-2017 IPR001486 Truncated hemoglobin GO:0019825 GTHT12_RS04375 2bf0f2202f8af284d782daed098957d5 137 SUPERFAMILY SSF46458 7 124 4.84E-42 T 06-07-2017 IPR009050 Globin-like GTHT12_RS04375 2bf0f2202f8af284d782daed098957d5 137 Gene3D G3DSA:1.10.490.10 6 127 2.8E-48 T 06-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 GTHT12_RS01075 94b96586f0136f77b7e8a4546772dcbb 188 Pfam PF00881 Nitroreductase family 7 165 2.9E-23 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 GTHT12_RS01075 94b96586f0136f77b7e8a4546772dcbb 188 SUPERFAMILY SSF55469 1 184 1.07E-37 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 GTHT12_RS01075 94b96586f0136f77b7e8a4546772dcbb 188 PIRSF PIRSF000232 1 188 6.1E-43 T 06-07-2017 IPR026021 Putative NAD(P)H nitroreductase YdjA-like GTHT12_RS01075 94b96586f0136f77b7e8a4546772dcbb 188 Gene3D G3DSA:3.40.109.10 1 183 1.3E-41 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 GTHT12_RS10705 3ad87c4c44de431d7a4fc8d25a25724a 264 SUPERFAMILY SSF52540 2 234 2.01E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10705 3ad87c4c44de431d7a4fc8d25a25724a 264 SMART SM00382 31 233 3.4E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS10705 3ad87c4c44de431d7a4fc8d25a25724a 264 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS10705 3ad87c4c44de431d7a4fc8d25a25724a 264 Gene3D G3DSA:3.40.50.300 1 234 1.2E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10705 3ad87c4c44de431d7a4fc8d25a25724a 264 Pfam PF00005 ABC transporter 22 177 4.3E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS02955 515805d8ada14787eb398f68959ef639 425 SUPERFAMILY SSF103473 3 406 1.31E-59 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS02955 515805d8ada14787eb398f68959ef639 425 Gene3D G3DSA:1.20.1250.20 216 407 7.5E-22 T 06-07-2017 GTHT12_RS02955 515805d8ada14787eb398f68959ef639 425 Gene3D G3DSA:1.20.1250.20 4 189 2.9E-23 T 06-07-2017 GTHT12_RS02955 515805d8ada14787eb398f68959ef639 425 Pfam PF07690 Major Facilitator Superfamily 18 239 9.6E-27 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS05150 c7747f6d23bcfbd957bae13a4096c941 361 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 193 358 2.6E-21 T 06-07-2017 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 GTHT12_RS05150 c7747f6d23bcfbd957bae13a4096c941 361 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 2 360 9.3E-88 T 06-07-2017 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 GTHT12_RS00600 1b46e045ad40d79ec53814bce47421f6 233 PIRSF PIRSF002155 1 227 1.1E-83 T 06-07-2017 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00600 1b46e045ad40d79ec53814bce47421f6 233 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 45.57 T 06-07-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 GTHT12_RS00600 1b46e045ad40d79ec53814bce47421f6 233 Gene3D G3DSA:3.40.50.790 69 159 1.3E-44 T 06-07-2017 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich GTHT12_RS00600 1b46e045ad40d79ec53814bce47421f6 233 SUPERFAMILY SSF56808 6 226 8.24E-88 T 06-07-2017 IPR023674 Ribosomal protein L1-like GTHT12_RS00600 1b46e045ad40d79ec53814bce47421f6 233 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 2.2E-109 T 06-07-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 GTHT12_RS00600 1b46e045ad40d79ec53814bce47421f6 233 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 06-07-2017 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00600 1b46e045ad40d79ec53814bce47421f6 233 Gene3D G3DSA:3.30.190.20 18 68 3.6E-51 T 06-07-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 GTHT12_RS00600 1b46e045ad40d79ec53814bce47421f6 233 Gene3D G3DSA:3.30.190.20 161 226 3.6E-51 T 06-07-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 GTHT12_RS00600 1b46e045ad40d79ec53814bce47421f6 233 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 1.3E-58 T 06-07-2017 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein GTHT12_RS15950 f9ec79c2881dded2640cecb6b261405d 158 Gene3D G3DSA:3.90.79.10 9 147 2.5E-34 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 GTHT12_RS15950 f9ec79c2881dded2640cecb6b261405d 158 SUPERFAMILY SSF55811 9 134 1.33E-31 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 GTHT12_RS15950 f9ec79c2881dded2640cecb6b261405d 158 PRINTS PR00502 NUDIX hydrolase family signature 32 46 1.0E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 GTHT12_RS15950 f9ec79c2881dded2640cecb6b261405d 158 PRINTS PR00502 NUDIX hydrolase family signature 46 61 1.0E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 GTHT12_RS15950 f9ec79c2881dded2640cecb6b261405d 158 Pfam PF00293 NUDIX domain 8 129 2.0E-19 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 GTHT12_RS18200 37386117899f1a8fca840575117c624e 286 Pfam PF02195 ParB-like nuclease domain 27 114 3.9E-27 T 06-07-2017 IPR003115 ParB/Sulfiredoxin GTHT12_RS18200 37386117899f1a8fca840575117c624e 286 SUPERFAMILY SSF110849 26 117 1.02E-28 T 06-07-2017 IPR003115 ParB/Sulfiredoxin GTHT12_RS18200 37386117899f1a8fca840575117c624e 286 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 23 195 1.0E-63 T 06-07-2017 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 GTHT12_RS18200 37386117899f1a8fca840575117c624e 286 SUPERFAMILY SSF109709 107 218 7.59E-38 T 06-07-2017 GTHT12_RS18200 37386117899f1a8fca840575117c624e 286 SMART SM00470 26 115 7.3E-36 T 06-07-2017 IPR003115 ParB/Sulfiredoxin GTHT12_RS18200 37386117899f1a8fca840575117c624e 286 Gene3D G3DSA:3.90.1530.10 21 121 1.3E-37 T 06-07-2017 GTHT12_RS18810 226b35b3a367694f92f7f7e91991135d 359 Pfam PF13800 Sigma factor regulator N-terminal 56 148 4.3E-18 T 06-07-2017 IPR029101 Sigma factor regulator, N-terminal GTHT12_RS18810 226b35b3a367694f92f7f7e91991135d 359 Pfam PF13791 Sigma factor regulator C-terminal 203 349 5.8E-29 T 06-07-2017 IPR025672 Sigma factor regulator C-terminal domain GTHT12_RS16395 9510c6c081b97e67aae3545ce6b389b9 377 SUPERFAMILY SSF53756 95 362 1.78E-8 T 06-07-2017 GTHT12_RS16395 9510c6c081b97e67aae3545ce6b389b9 377 TIGRFAM TIGR03609 S_layer_CsaB: polysaccharide pyruvyl transferase CsaB 4 314 9.3E-71 T 06-07-2017 IPR019896 Polysaccharide pyruvyl transferase, CsaB GTHT12_RS16395 9510c6c081b97e67aae3545ce6b389b9 377 Pfam PF04230 Polysaccharide pyruvyl transferase 15 302 4.9E-65 T 06-07-2017 IPR007345 Polysaccharide pyruvyl transferase GTHT12_RS01030 c2033119e57e58308f20963cfd2f73b3 541 Pfam PF00501 AMP-binding enzyme 32 435 2.5E-83 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GTHT12_RS01030 c2033119e57e58308f20963cfd2f73b3 541 Gene3D G3DSA:2.30.38.10 354 428 1.2E-24 T 06-07-2017 GTHT12_RS01030 c2033119e57e58308f20963cfd2f73b3 541 Gene3D G3DSA:3.30.300.30 430 533 2.7E-31 T 06-07-2017 GTHT12_RS01030 c2033119e57e58308f20963cfd2f73b3 541 TIGRFAM TIGR02275 DHB_AMP_lig: (2,3-dihydroxybenzoyl)adenylate synthase 7 526 5.7E-250 T 06-07-2017 IPR011963 2,3-dihydroxybenzoate-AMP ligase GO:0008668|GO:0019290 GTHT12_RS01030 c2033119e57e58308f20963cfd2f73b3 541 Gene3D G3DSA:3.40.50.980 191 353 5.0E-40 T 06-07-2017 GTHT12_RS01030 c2033119e57e58308f20963cfd2f73b3 541 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 06-07-2017 IPR020845 AMP-binding, conserved site GTHT12_RS01030 c2033119e57e58308f20963cfd2f73b3 541 Gene3D G3DSA:3.40.50.980 26 190 2.0E-28 T 06-07-2017 GTHT12_RS01030 c2033119e57e58308f20963cfd2f73b3 541 Pfam PF13193 AMP-binding enzyme C-terminal domain 444 519 1.1E-15 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain GTHT12_RS01030 c2033119e57e58308f20963cfd2f73b3 541 SUPERFAMILY SSF56801 8 531 7.72E-146 T 06-07-2017 GTHT12_RS14605 fa1a599989c722a6b3d74062c561d787 360 Gene3D G3DSA:1.20.59.10 2 87 6.1E-21 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 GTHT12_RS14605 fa1a599989c722a6b3d74062c561d787 360 SMART SM00830 10 89 9.9E-23 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 GTHT12_RS14605 fa1a599989c722a6b3d74062c561d787 360 TIGRFAM TIGR01801 CM_A: chorismate mutase 1 102 1.6E-44 T 06-07-2017 IPR010954 Chorismate mutase, Firmicutes/Deinococcus KEGG: 00400+2.5.1.54+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6164|MetaCyc: PWY-6627|MetaCyc: PWY-7626 GTHT12_RS14605 fa1a599989c722a6b3d74062c561d787 360 Pfam PF00793 DAHP synthetase I family 110 350 6.2E-85 T 06-07-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 GTHT12_RS14605 fa1a599989c722a6b3d74062c561d787 360 Gene3D G3DSA:3.20.20.70 96 355 1.0E-98 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS14605 fa1a599989c722a6b3d74062c561d787 360 SUPERFAMILY SSF51569 30 354 1.65E-103 T 06-07-2017 GTHT12_RS14605 fa1a599989c722a6b3d74062c561d787 360 Pfam PF01817 Chorismate mutase type II 10 87 4.0E-18 T 06-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 GTHT12_RS14605 fa1a599989c722a6b3d74062c561d787 360 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 95 352 1.0E-123 T 06-07-2017 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 GTHT12_RS10900 293e88e51805eaa3f73d6e79a8431cd9 282 Gene3D G3DSA:3.30.1240.10 80 193 4.4E-28 T 06-07-2017 GTHT12_RS10900 293e88e51805eaa3f73d6e79a8431cd9 282 ProSitePatterns PS01228 Hypothetical cof family signature 1. 2 13 - T 06-07-2017 IPR000150 Cof protein GO:0016787 GTHT12_RS10900 293e88e51805eaa3f73d6e79a8431cd9 282 Pfam PF08282 haloacid dehalogenase-like hydrolase 3 273 7.2E-63 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS10900 293e88e51805eaa3f73d6e79a8431cd9 282 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 2 248 1.1E-24 T 06-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 GTHT12_RS10900 293e88e51805eaa3f73d6e79a8431cd9 282 Gene3D G3DSA:3.40.50.1000 194 279 4.3E-51 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS10900 293e88e51805eaa3f73d6e79a8431cd9 282 Gene3D G3DSA:3.40.50.1000 2 70 4.3E-51 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS10900 293e88e51805eaa3f73d6e79a8431cd9 282 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 2 274 6.9E-55 T 06-07-2017 IPR000150 Cof protein GO:0016787 GTHT12_RS10900 293e88e51805eaa3f73d6e79a8431cd9 282 SUPERFAMILY SSF56784 2 279 2.1E-64 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS01130 a2287ef2006357315d2be0876cae8fb4 457 Pfam PF00158 Sigma-54 interaction domain 142 301 2.4E-40 T 06-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 GTHT12_RS01130 a2287ef2006357315d2be0876cae8fb4 457 SMART SM00091 10 78 5.7E-4 T 06-07-2017 IPR000014 PAS domain GTHT12_RS01130 a2287ef2006357315d2be0876cae8fb4 457 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 433 453 1.3E-8 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GTHT12_RS01130 a2287ef2006357315d2be0876cae8fb4 457 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 416 433 1.3E-8 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GTHT12_RS01130 a2287ef2006357315d2be0876cae8fb4 457 Pfam PF08448 PAS fold 18 123 5.5E-7 T 06-07-2017 IPR013656 PAS fold-4 GTHT12_RS01130 a2287ef2006357315d2be0876cae8fb4 457 SUPERFAMILY SSF46689 350 452 2.08E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS01130 a2287ef2006357315d2be0876cae8fb4 457 Pfam PF02954 Bacterial regulatory protein, Fis family 410 450 6.6E-13 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 GTHT12_RS01130 a2287ef2006357315d2be0876cae8fb4 457 Gene3D G3DSA:3.40.50.300 140 309 2.3E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01130 a2287ef2006357315d2be0876cae8fb4 457 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 350 359 - T 06-07-2017 IPR025944 Sigma-54 interaction domain, conserved site GTHT12_RS01130 a2287ef2006357315d2be0876cae8fb4 457 SUPERFAMILY SSF52540 141 380 8.52E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01130 a2287ef2006357315d2be0876cae8fb4 457 Gene3D G3DSA:3.30.450.20 11 130 4.1E-13 T 06-07-2017 GTHT12_RS01130 a2287ef2006357315d2be0876cae8fb4 457 Gene3D G3DSA:1.10.8.60 310 384 2.7E-24 T 06-07-2017 GTHT12_RS01130 a2287ef2006357315d2be0876cae8fb4 457 Gene3D G3DSA:1.10.10.60 405 449 1.2E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS01130 a2287ef2006357315d2be0876cae8fb4 457 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 10 123 5.5E-9 T 06-07-2017 IPR000014 PAS domain GTHT12_RS01130 a2287ef2006357315d2be0876cae8fb4 457 SUPERFAMILY SSF55785 3 115 8.2E-13 T 06-07-2017 IPR000014 PAS domain GTHT12_RS15505 6256201ae3e3ac781aaa71961ba40bee 91 Pfam PF06265 Protein of unknown function (DUF1027) 4 87 6.2E-39 T 06-07-2017 IPR009370 Protein of unknown function DUF1027 GTHT12_RS15505 6256201ae3e3ac781aaa71961ba40bee 91 PIRSF PIRSF012565 1 91 2.1E-49 T 06-07-2017 IPR009370 Protein of unknown function DUF1027 GTHT12_RS03930 2487a14328c619c07fde4027d405eaff 328 Gene3D G3DSA:3.40.50.970 5 327 1.4E-113 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS03930 2487a14328c619c07fde4027d405eaff 328 SUPERFAMILY SSF52518 3 327 1.09E-89 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS03930 2487a14328c619c07fde4027d405eaff 328 Pfam PF00676 Dehydrogenase E1 component 46 319 1.8E-72 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 GTHT12_RS14755 e70bd9e99a8569c069fcc84ef20267e0 87 Pfam PF10732 Protein of unknown function (DUF2524) 1 84 4.1E-38 T 06-07-2017 IPR019668 Uncharacterised protein family YtzC GTHT12_RS06315 ad700a5cba07bb151cb0dd4d550a52a3 129 Pfam PF00460 Flagella basal body rod protein 15 38 4.2E-7 T 06-07-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 GTHT12_RS06315 ad700a5cba07bb151cb0dd4d550a52a3 129 PIRSF PIRSF002889 2 128 1.4E-35 T 06-07-2017 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 GTHT12_RS06315 ad700a5cba07bb151cb0dd4d550a52a3 129 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 4 126 2.5E-35 T 06-07-2017 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 GTHT12_RS00005 e91791bca3b83aab5456951f24bf2b2b 450 SUPERFAMILY SSF52540 113 325 7.99E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00005 e91791bca3b83aab5456951f24bf2b2b 450 Pfam PF00308 Bacterial dnaA protein 113 329 2.3E-107 T 06-07-2017 IPR013317 Chromosomal replication initiator protein DnaA GTHT12_RS00005 e91791bca3b83aab5456951f24bf2b2b 450 Gene3D G3DSA:1.10.8.60 279 347 1.7E-32 T 06-07-2017 GTHT12_RS00005 e91791bca3b83aab5456951f24bf2b2b 450 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 358 426 5.4E-31 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 GTHT12_RS00005 e91791bca3b83aab5456951f24bf2b2b 450 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 5 448 35.393 T 06-07-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 GTHT12_RS00005 e91791bca3b83aab5456951f24bf2b2b 450 Gene3D G3DSA:3.40.50.300 106 277 5.9E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00005 e91791bca3b83aab5456951f24bf2b2b 450 SMART SM00382 145 273 3.3E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS00005 e91791bca3b83aab5456951f24bf2b2b 450 ProSitePatterns PS01008 DnaA protein signature. 407 426 - T 06-07-2017 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 GTHT12_RS00005 e91791bca3b83aab5456951f24bf2b2b 450 SUPERFAMILY SSF48295 344 449 9.68E-38 T 06-07-2017 IPR010921 Trp repressor/replication initiator GO:0043565 GTHT12_RS00005 e91791bca3b83aab5456951f24bf2b2b 450 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 8 447 4.9E-191 T 06-07-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 GTHT12_RS00005 e91791bca3b83aab5456951f24bf2b2b 450 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 146 166 6.5E-54 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like GTHT12_RS00005 e91791bca3b83aab5456951f24bf2b2b 450 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 407 426 6.5E-54 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like GTHT12_RS00005 e91791bca3b83aab5456951f24bf2b2b 450 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 178 192 6.5E-54 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like GTHT12_RS00005 e91791bca3b83aab5456951f24bf2b2b 450 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 244 271 6.5E-54 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like GTHT12_RS00005 e91791bca3b83aab5456951f24bf2b2b 450 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 210 224 6.5E-54 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like GTHT12_RS00005 e91791bca3b83aab5456951f24bf2b2b 450 Gene3D G3DSA:1.10.1750.10 348 449 7.0E-42 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 GTHT12_RS00005 e91791bca3b83aab5456951f24bf2b2b 450 SMART SM00760 357 426 2.0E-42 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 GTHT12_RS00005 e91791bca3b83aab5456951f24bf2b2b 450 Pfam PF11638 DnaA N-terminal domain 6 65 7.4E-17 T 06-07-2017 IPR024633 DnaA N-terminal domain GTHT12_RS08980 399b7c82e520f3c6985e1aa284d80379 118 Pfam PF13592 Winged helix-turn helix 72 113 1.6E-7 T 06-07-2017 IPR025959 Winged helix-turn helix domain GTHT12_RS10315 280e1b1947dbde0c62202aa594ee31b5 324 ProSitePatterns PS01053 Arginase family signature. 234 255 - T 06-07-2017 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 GTHT12_RS10315 280e1b1947dbde0c62202aa594ee31b5 324 Pfam PF00491 Arginase family 32 303 2.1E-87 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 GTHT12_RS10315 280e1b1947dbde0c62202aa594ee31b5 324 PRINTS PR00116 Arginase signature 118 133 5.4E-13 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 GTHT12_RS10315 280e1b1947dbde0c62202aa594ee31b5 324 PRINTS PR00116 Arginase signature 231 260 5.4E-13 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 GTHT12_RS10315 280e1b1947dbde0c62202aa594ee31b5 324 Gene3D G3DSA:3.40.800.10 5 311 1.2E-112 T 06-07-2017 IPR023696 Ureohydrolase domain GTHT12_RS10315 280e1b1947dbde0c62202aa594ee31b5 324 TIGRFAM TIGR01230 agmatinase: agmatinase 28 304 3.5E-67 T 06-07-2017 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 GTHT12_RS10315 280e1b1947dbde0c62202aa594ee31b5 324 SUPERFAMILY SSF52768 11 307 4.32E-100 T 06-07-2017 GTHT12_RS10315 280e1b1947dbde0c62202aa594ee31b5 324 PIRSF PIRSF036979 8 310 1.1E-100 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 GTHT12_RS06300 a031b4427dc85466ce927885f849fa94 180 PIRSF PIRSF039093 1 180 9.8E-83 T 06-07-2017 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 GTHT12_RS06300 a031b4427dc85466ce927885f849fa94 180 SUPERFAMILY SSF56235 4 179 2.44E-59 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal GTHT12_RS06300 a031b4427dc85466ce927885f849fa94 180 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 180 40.96 T 06-07-2017 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 GTHT12_RS06300 a031b4427dc85466ce927885f849fa94 180 Gene3D G3DSA:3.60.20.10 7 180 1.7E-76 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal GTHT12_RS06300 a031b4427dc85466ce927885f849fa94 180 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 180 9.9E-82 T 06-07-2017 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 GTHT12_RS06300 a031b4427dc85466ce927885f849fa94 180 Pfam PF00227 Proteasome subunit 5 178 3.5E-26 T 06-07-2017 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 GTHT12_RS14910 d761aa89a9a3a9369c1794de8329e499 254 SUPERFAMILY SSF109635 2 90 8.5E-16 T 06-07-2017 GTHT12_RS14910 d761aa89a9a3a9369c1794de8329e499 254 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 89 116 2.0E-10 T 06-07-2017 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 GTHT12_RS14910 d761aa89a9a3a9369c1794de8329e499 254 TIGRFAM TIGR02890 bacill_yteA: regulatory protein, yteA family 5 165 1.7E-66 T 06-07-2017 IPR014240 Regulatory protein, YteA family GTHT12_RS14910 d761aa89a9a3a9369c1794de8329e499 254 SUPERFAMILY SSF57716 91 119 2.64E-6 T 06-07-2017 GTHT12_RS05035 bf2d9e6db287535ca40765781384cae0 271 SUPERFAMILY SSF56317 2 265 2.49E-79 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 GTHT12_RS05035 bf2d9e6db287535ca40765781384cae0 271 Gene3D G3DSA:3.60.110.10 2 266 1.8E-84 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 GTHT12_RS05035 bf2d9e6db287535ca40765781384cae0 271 Pfam PF00795 Carbon-nitrogen hydrolase 4 246 2.7E-51 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 GTHT12_RS15275 4c8314c7c40542dce302d08aff70550c 134 Gene3D G3DSA:3.30.310.100 1 132 1.3E-47 T 06-07-2017 IPR014967 Uncharacterised protein family, YugN-like GTHT12_RS15275 4c8314c7c40542dce302d08aff70550c 134 Pfam PF08868 YugN-like family 3 131 1.3E-56 T 06-07-2017 IPR014967 Uncharacterised protein family, YugN-like GTHT12_RS15275 4c8314c7c40542dce302d08aff70550c 134 SUPERFAMILY SSF160755 1 132 8.24E-40 T 06-07-2017 IPR014967 Uncharacterised protein family, YugN-like GTHT12_RS13250 85175a8ffc33cc24eb5538976eeefaef 179 Pfam PF01066 CDP-alcohol phosphatidyltransferase 17 81 8.5E-14 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 GTHT12_RS13250 85175a8ffc33cc24eb5538976eeefaef 179 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 59 81 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 GTHT12_RS13250 85175a8ffc33cc24eb5538976eeefaef 179 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 23 173 2.5E-42 T 06-07-2017 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 GTHT12_RS14085 38bb61cadd049431724122f165f5947e 133 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 121 18.109 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 GTHT12_RS14085 38bb61cadd049431724122f165f5947e 133 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 116 8.4E-22 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 GTHT12_RS08275 1898f7194f3760d0e07191ab75e77b12 555 PRINTS PR01036 Tetracycline resistance protein TetB signature 68 92 9.6E-11 T 06-07-2017 GTHT12_RS08275 1898f7194f3760d0e07191ab75e77b12 555 PRINTS PR01036 Tetracycline resistance protein TetB signature 159 179 9.6E-11 T 06-07-2017 GTHT12_RS08275 1898f7194f3760d0e07191ab75e77b12 555 PRINTS PR01036 Tetracycline resistance protein TetB signature 189 213 9.6E-11 T 06-07-2017 GTHT12_RS08275 1898f7194f3760d0e07191ab75e77b12 555 PRINTS PR01036 Tetracycline resistance protein TetB signature 353 377 9.6E-11 T 06-07-2017 GTHT12_RS08275 1898f7194f3760d0e07191ab75e77b12 555 SUPERFAMILY SSF103473 299 470 2.22E-72 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS08275 1898f7194f3760d0e07191ab75e77b12 555 SUPERFAMILY SSF103473 62 248 2.22E-72 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS08275 1898f7194f3760d0e07191ab75e77b12 555 SUPERFAMILY SSF103473 522 549 2.22E-72 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS08275 1898f7194f3760d0e07191ab75e77b12 555 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 66 545 1.3E-136 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 GTHT12_RS08275 1898f7194f3760d0e07191ab75e77b12 555 Gene3D G3DSA:1.20.1250.20 312 476 2.2E-23 T 06-07-2017 GTHT12_RS08275 1898f7194f3760d0e07191ab75e77b12 555 Gene3D G3DSA:1.20.1250.20 527 547 2.2E-23 T 06-07-2017 GTHT12_RS08275 1898f7194f3760d0e07191ab75e77b12 555 Pfam PF07690 Major Facilitator Superfamily 69 460 5.9E-53 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS08275 1898f7194f3760d0e07191ab75e77b12 555 Gene3D G3DSA:1.20.1250.20 64 245 4.4E-30 T 06-07-2017 GTHT12_RS16795 520bb49a81d97d84e1f6d3213ab01bcf 323 SUPERFAMILY SSF75005 16 310 7.77E-59 T 06-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain GTHT12_RS16795 520bb49a81d97d84e1f6d3213ab01bcf 323 Pfam PF08950 Protein of unknown function (DUF1861) 26 309 3.3E-132 T 06-07-2017 IPR015045 Protein of unknown function DUF1861 GTHT12_RS09625 f9e2b5c333d85e207e43a4879fcf8f48 133 Gene3D G3DSA:2.60.120.460 3 130 3.9E-45 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 GTHT12_RS09625 f9e2b5c333d85e207e43a4879fcf8f48 133 Pfam PF01894 Uncharacterised protein family UPF0047 17 130 6.5E-39 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 GTHT12_RS09625 f9e2b5c333d85e207e43a4879fcf8f48 133 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 5 131 8.0E-54 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 GTHT12_RS09625 f9e2b5c333d85e207e43a4879fcf8f48 133 SUPERFAMILY SSF111038 3 133 4.19E-46 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 GTHT12_RS09625 f9e2b5c333d85e207e43a4879fcf8f48 133 PIRSF PIRSF004681 1 133 8.3E-37 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 GTHT12_RS13220 67c6c50bd0c207b9065539787394da33 97 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 8 96 3.0E-43 T 06-07-2017 IPR001890 RNA-binding, CRM domain GO:0003723 GTHT12_RS13220 67c6c50bd0c207b9065539787394da33 97 SUPERFAMILY SSF75471 1 95 1.15E-33 T 06-07-2017 IPR001890 RNA-binding, CRM domain GO:0003723 GTHT12_RS13220 67c6c50bd0c207b9065539787394da33 97 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 2.4E-25 T 06-07-2017 IPR001890 RNA-binding, CRM domain GO:0003723 GTHT12_RS13220 67c6c50bd0c207b9065539787394da33 97 SMART SM01103 2 85 6.9E-47 T 06-07-2017 IPR001890 RNA-binding, CRM domain GO:0003723 GTHT12_RS13220 67c6c50bd0c207b9065539787394da33 97 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 96 1.6E-40 T 06-07-2017 IPR017924 RNA-binding protein YhbY GO:0003723 GTHT12_RS13220 67c6c50bd0c207b9065539787394da33 97 Gene3D G3DSA:3.30.110.60 1 95 8.9E-36 T 06-07-2017 IPR001890 RNA-binding, CRM domain GO:0003723 GTHT12_RS13630 aa376e09b540890250f0d31bbda69541 110 SUPERFAMILY SSF118010 1 108 1.57E-32 T 06-07-2017 GTHT12_RS13630 aa376e09b540890250f0d31bbda69541 110 Pfam PF04327 Cysteine peptidase C108, N-terminal of ribosomal L27 1 105 4.4E-26 T 06-07-2017 IPR007422 Cysteine peptidase C108, N-terminal of ribosomal L27 GTHT12_RS13630 aa376e09b540890250f0d31bbda69541 110 Gene3D G3DSA:3.30.70.1490 9 109 1.3E-26 T 06-07-2017 GTHT12_RS10445 82f8d07bc83bb4d48772e622f411e0d7 319 Gene3D G3DSA:3.40.1190.20 1 310 1.8E-92 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS10445 82f8d07bc83bb4d48772e622f411e0d7 319 Pfam PF00294 pfkB family carbohydrate kinase 5 299 2.4E-58 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB GTHT12_RS10445 82f8d07bc83bb4d48772e622f411e0d7 319 SUPERFAMILY SSF53613 1 308 1.12E-85 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS10445 82f8d07bc83bb4d48772e622f411e0d7 319 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 252 265 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 GTHT12_RS02925 9213d377fecae68c447ff545ef036587 53 TIGRFAM TIGR03091 SASP_sspK: small, acid-soluble spore protein K 16 47 2.4E-23 T 06-07-2017 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 GTHT12_RS02925 9213d377fecae68c447ff545ef036587 53 Hamap MF_01504 Small, acid-soluble spore protein K [sspK]. 1 49 19.22 T 06-07-2017 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 GTHT12_RS02925 9213d377fecae68c447ff545ef036587 53 Pfam PF08176 Small acid-soluble spore protein K family 1 47 4.9E-29 T 06-07-2017 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 GTHT12_RS06520 c7a76e8b8d6f7561d6b4c789049a727c 567 SUPERFAMILY SSF52954 460 566 6.38E-29 T 06-07-2017 IPR004154 Anticodon-binding GTHT12_RS06520 c7a76e8b8d6f7561d6b4c789049a727c 567 PIRSF PIRSF001535 1 567 5.8E-279 T 06-07-2017 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 GTHT12_RS06520 c7a76e8b8d6f7561d6b4c789049a727c 567 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 566 42.206 T 06-07-2017 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 GTHT12_RS06520 c7a76e8b8d6f7561d6b4c789049a727c 567 Pfam PF04073 Aminoacyl-tRNA editing domain 257 373 6.9E-29 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 GTHT12_RS06520 c7a76e8b8d6f7561d6b4c789049a727c 567 Gene3D G3DSA:3.90.960.10 255 385 4.5E-34 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 GTHT12_RS06520 c7a76e8b8d6f7561d6b4c789049a727c 567 SUPERFAMILY SSF55681 9 237 1.03E-108 T 06-07-2017 GTHT12_RS06520 c7a76e8b8d6f7561d6b4c789049a727c 567 SUPERFAMILY SSF55681 404 474 1.03E-108 T 06-07-2017 GTHT12_RS06520 c7a76e8b8d6f7561d6b4c789049a727c 567 SUPERFAMILY SSF55826 218 387 6.28E-35 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 GTHT12_RS06520 c7a76e8b8d6f7561d6b4c789049a727c 567 Gene3D G3DSA:3.40.50.800 468 566 7.6E-28 T 06-07-2017 IPR004154 Anticodon-binding GTHT12_RS06520 c7a76e8b8d6f7561d6b4c789049a727c 567 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 455 5.7E-58 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 GTHT12_RS06520 c7a76e8b8d6f7561d6b4c789049a727c 567 Gene3D G3DSA:3.30.930.10 386 467 8.2E-108 T 06-07-2017 GTHT12_RS06520 c7a76e8b8d6f7561d6b4c789049a727c 567 Gene3D G3DSA:3.30.930.10 11 234 8.2E-108 T 06-07-2017 GTHT12_RS06520 c7a76e8b8d6f7561d6b4c789049a727c 567 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 1.3E-19 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 GTHT12_RS06520 c7a76e8b8d6f7561d6b4c789049a727c 567 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 1.3E-19 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 GTHT12_RS06520 c7a76e8b8d6f7561d6b4c789049a727c 567 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 1.3E-19 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 GTHT12_RS06520 c7a76e8b8d6f7561d6b4c789049a727c 567 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 1.3E-19 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 GTHT12_RS06520 c7a76e8b8d6f7561d6b4c789049a727c 567 Pfam PF03129 Anticodon binding domain 474 563 4.4E-18 T 06-07-2017 IPR004154 Anticodon-binding GTHT12_RS06520 c7a76e8b8d6f7561d6b4c789049a727c 567 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 559 4.0E-243 T 06-07-2017 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 GTHT12_RS01810 a68d28e868054bfce82c29b940b697eb 299 Pfam PF01867 CRISPR associated protein Cas1 7 230 2.7E-28 T 06-07-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 GTHT12_RS01810 a68d28e868054bfce82c29b940b697eb 299 TIGRFAM TIGR03639 cas1_NMENI: CRISPR-associated endonuclease Cas1, subtype II/NMENI 3 274 6.3E-86 T 06-07-2017 IPR019855 CRISPR-associated protein Cas1, NMENI subtype GO:0004520|GO:0043571|GO:0046872 GTHT12_RS01810 a68d28e868054bfce82c29b940b697eb 299 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 6 276 1.4E-25 T 06-07-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 GTHT12_RS01810 a68d28e868054bfce82c29b940b697eb 299 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 3 286 16.469 T 06-07-2017 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 GTHT12_RS17385 af69ef4db0cf4792e1c8825049b831d1 149 SUPERFAMILY SSF46785 2 62 4.89E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS17385 af69ef4db0cf4792e1c8825049b831d1 149 Pfam PF13404 AsnC-type helix-turn-helix domain 3 43 1.7E-15 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 GTHT12_RS17385 af69ef4db0cf4792e1c8825049b831d1 149 Pfam PF01037 Lrp/AsnC ligand binding domain 70 139 2.6E-18 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain GTHT12_RS17385 af69ef4db0cf4792e1c8825049b831d1 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 3.9E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 GTHT12_RS17385 af69ef4db0cf4792e1c8825049b831d1 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 3.9E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 GTHT12_RS17385 af69ef4db0cf4792e1c8825049b831d1 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 3.9E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 GTHT12_RS17385 af69ef4db0cf4792e1c8825049b831d1 149 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site GTHT12_RS17385 af69ef4db0cf4792e1c8825049b831d1 149 Gene3D G3DSA:3.30.70.920 66 142 2.0E-21 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain GTHT12_RS17385 af69ef4db0cf4792e1c8825049b831d1 149 SMART SM00344 3 109 7.4E-41 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 GTHT12_RS17385 af69ef4db0cf4792e1c8825049b831d1 149 Gene3D G3DSA:1.10.10.10 1 55 1.5E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS17385 af69ef4db0cf4792e1c8825049b831d1 149 SUPERFAMILY SSF54909 65 142 1.88E-18 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel GTHT12_RS09100 6365f9629a609186b320d463ad440736 124 Gene3D G3DSA:1.10.10.10 2 123 2.2E-39 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS09100 6365f9629a609186b320d463ad440736 124 PIRSF PIRSF021424 1 123 3.2E-71 T 06-07-2017 IPR003432 Replication terminator protein GO:0003677|GO:0006274 GTHT12_RS09100 6365f9629a609186b320d463ad440736 124 Pfam PF02334 Replication terminator protein 3 123 2.6E-54 T 06-07-2017 IPR003432 Replication terminator protein GO:0003677|GO:0006274 GTHT12_RS09100 6365f9629a609186b320d463ad440736 124 ProDom PD077583 REPLICATION TRANSCRIPTION DNA-BINDING TERMINATOR REGULATION TERMINATION 3D-STRUCTURE 10 123 8.0E-59 T 06-07-2017 IPR003432 Replication terminator protein GO:0003677|GO:0006274 GTHT12_RS09100 6365f9629a609186b320d463ad440736 124 SUPERFAMILY SSF46785 4 105 3.63E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS07965 eeea5b106e81d8e392354a4c49df0599 156 SUPERFAMILY SSF49503 59 155 1.57E-32 T 06-07-2017 IPR008972 Cupredoxin GTHT12_RS07965 eeea5b106e81d8e392354a4c49df0599 156 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 81 154 8.2E-13 T 06-07-2017 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS07965 eeea5b106e81d8e392354a4c49df0599 156 Gene3D G3DSA:1.20.1070.10 3 37 6.8E-9 T 06-07-2017 GTHT12_RS07965 eeea5b106e81d8e392354a4c49df0599 156 Gene3D G3DSA:2.60.40.420 57 154 2.4E-27 T 06-07-2017 IPR008972 Cupredoxin GTHT12_RS07965 eeea5b106e81d8e392354a4c49df0599 156 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 100 148 - T 06-07-2017 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS07965 eeea5b106e81d8e392354a4c49df0599 156 PRINTS PR01166 Cytochrome c oxidase subunit II signature 137 154 5.7E-5 T 06-07-2017 GTHT12_RS07965 eeea5b106e81d8e392354a4c49df0599 156 PRINTS PR01166 Cytochrome c oxidase subunit II signature 99 119 5.7E-5 T 06-07-2017 GTHT12_RS07965 eeea5b106e81d8e392354a4c49df0599 156 PRINTS PR01166 Cytochrome c oxidase subunit II signature 75 96 5.7E-5 T 06-07-2017 GTHT12_RS00825 63158b32ca6ffb18a655d68e2314d112 145 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 142 3.3E-67 T 06-07-2017 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00825 63158b32ca6ffb18a655d68e2314d112 145 SUPERFAMILY SSF52161 5 143 8.76E-63 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00825 63158b32ca6ffb18a655d68e2314d112 145 ProSitePatterns PS00783 Ribosomal protein L13 signature. 106 128 - T 06-07-2017 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00825 63158b32ca6ffb18a655d68e2314d112 145 PIRSF PIRSF002181 1 143 6.4E-52 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00825 63158b32ca6ffb18a655d68e2314d112 145 Pfam PF00572 Ribosomal protein L13 15 139 3.8E-59 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00825 63158b32ca6ffb18a655d68e2314d112 145 Gene3D G3DSA:3.90.1180.10 4 142 9.2E-67 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00825 63158b32ca6ffb18a655d68e2314d112 145 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 144 29.945 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 GTHT12_RS03990 339e4bdd48f06c9b33f19079ab45f322 79 Pfam PF07609 Protein of unknown function (DUF1572) 4 76 9.8E-33 T 06-07-2017 IPR011466 Protein of unknown function DUF1572 GTHT12_RS03990 339e4bdd48f06c9b33f19079ab45f322 79 SUPERFAMILY SSF109854 3 67 7.33E-13 T 06-07-2017 GTHT12_RS03990 339e4bdd48f06c9b33f19079ab45f322 79 Gene3D G3DSA:1.20.120.450 2 64 1.1E-8 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase GTHT12_RS18875 feb1539acbee12057e4b7bde2156ee60 71 Gene3D G3DSA:1.10.443.10 8 69 8.7E-15 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS18875 feb1539acbee12057e4b7bde2156ee60 71 SUPERFAMILY SSF56349 12 68 1.8E-13 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 GTHT12_RS18875 feb1539acbee12057e4b7bde2156ee60 71 Pfam PF00589 Phage integrase family 12 57 7.3E-10 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS15780 a63a0624a66eb9bfb3f190cc79b9c5f9 389 Gene3D G3DSA:3.40.50.2300 157 279 2.8E-10 T 06-07-2017 GTHT12_RS15780 a63a0624a66eb9bfb3f190cc79b9c5f9 389 Gene3D G3DSA:3.40.50.2300 302 368 1.6E-47 T 06-07-2017 GTHT12_RS15780 a63a0624a66eb9bfb3f190cc79b9c5f9 389 Gene3D G3DSA:3.40.50.2300 29 156 1.6E-47 T 06-07-2017 GTHT12_RS15780 a63a0624a66eb9bfb3f190cc79b9c5f9 389 Pfam PF13458 Periplasmic binding protein 31 383 7.8E-63 T 06-07-2017 IPR028081 Leucine-binding protein domain GTHT12_RS15780 a63a0624a66eb9bfb3f190cc79b9c5f9 389 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 263 281 1.2E-6 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 GTHT12_RS15780 a63a0624a66eb9bfb3f190cc79b9c5f9 389 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 32 48 1.2E-6 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 GTHT12_RS15780 a63a0624a66eb9bfb3f190cc79b9c5f9 389 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 54 70 1.2E-6 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 GTHT12_RS15780 a63a0624a66eb9bfb3f190cc79b9c5f9 389 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 73 91 1.2E-6 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 GTHT12_RS15780 a63a0624a66eb9bfb3f190cc79b9c5f9 389 SUPERFAMILY SSF53822 30 386 1.81E-81 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS03140 07b422ccdceb50c22ec72389a6426b6c 158 PIRSF PIRSF000239 1 155 8.1E-33 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GTHT12_RS03140 07b422ccdceb50c22ec72389a6426b6c 158 Pfam PF00578 AhpC/TSA family 5 132 1.7E-43 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GTHT12_RS03140 07b422ccdceb50c22ec72389a6426b6c 158 SUPERFAMILY SSF52833 3 154 3.74E-58 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS03140 07b422ccdceb50c22ec72389a6426b6c 158 Gene3D G3DSA:3.40.30.10 2 154 2.3E-59 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS15010 188be6ce37d898c91b0ab3b7dd175474 90 Pfam PF13143 Protein of unknown function (DUF3986) 2 87 1.1E-28 T 06-07-2017 IPR025047 Protein of unknown function DUF3986 GTHT12_RS10555 ec773611cd82f0df78a8ddf721618819 175 SMART SM00867 3 173 2.3E-67 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like GTHT12_RS10555 ec773611cd82f0df78a8ddf721618819 175 Gene3D G3DSA:2.40.128.110 3 172 9.0E-61 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like GTHT12_RS10555 ec773611cd82f0df78a8ddf721618819 175 Pfam PF04264 YceI-like domain 4 172 6.3E-45 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like GTHT12_RS10555 ec773611cd82f0df78a8ddf721618819 175 SUPERFAMILY SSF101874 3 172 2.88E-54 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like GTHT12_RS17285 5e474d566e572bbfb34047a29975badc 224 Pfam PF02397 Bacterial sugar transferase 30 218 2.5E-63 T 06-07-2017 IPR003362 Bacterial sugar transferase GTHT12_RS17285 5e474d566e572bbfb34047a29975badc 224 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 25 223 5.3E-90 T 06-07-2017 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase GTHT12_RS02570 b2234183a988ecff652fc9af7f6e711c 388 Pfam PF00872 Transposase, Mutator family 13 365 1.1E-98 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS02570 b2234183a988ecff652fc9af7f6e711c 388 ProSitePatterns PS01007 Transposases, Mutator family, signature. 220 244 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS09145 86819f75759ff65909d32731d57b83d7 237 TIGRFAM TIGR02404 trehalos_R_Bsub: trehalose operon repressor 5 236 8.9E-96 T 06-07-2017 IPR012770 Trehalose operon transcriptional repressor GTHT12_RS09145 86819f75759ff65909d32731d57b83d7 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 1.5E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS09145 86819f75759ff65909d32731d57b83d7 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 1.5E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS09145 86819f75759ff65909d32731d57b83d7 237 Gene3D G3DSA:1.10.10.10 3 62 1.8E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS09145 86819f75759ff65909d32731d57b83d7 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 68 7.3E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS09145 86819f75759ff65909d32731d57b83d7 237 Pfam PF07702 UTRA domain 95 229 3.6E-32 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 GTHT12_RS09145 86819f75759ff65909d32731d57b83d7 237 Gene3D G3DSA:3.40.1410.10 63 236 5.7E-52 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain GTHT12_RS09145 86819f75759ff65909d32731d57b83d7 237 SMART SM00866 90 229 8.8E-31 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 GTHT12_RS09145 86819f75759ff65909d32731d57b83d7 237 SUPERFAMILY SSF46785 4 72 2.49E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS09145 86819f75759ff65909d32731d57b83d7 237 SMART SM00345 9 68 6.5E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS09145 86819f75759ff65909d32731d57b83d7 237 SUPERFAMILY SSF64288 76 234 4.55E-41 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain GTHT12_RS04840 78b31ac40ff48079510a1e23eeba5880 344 SUPERFAMILY SSF47240 20 344 1.5E-87 T 06-07-2017 IPR009078 Ferritin-like superfamily GTHT12_RS04840 78b31ac40ff48079510a1e23eeba5880 344 Gene3D G3DSA:1.10.620.20 11 314 8.0E-87 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 GTHT12_RS04840 78b31ac40ff48079510a1e23eeba5880 344 PIRSF PIRSF000355 1 344 6.3E-126 T 06-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GTHT12_RS04840 78b31ac40ff48079510a1e23eeba5880 344 Pfam PF00268 Ribonucleotide reductase, small chain 29 307 1.1E-70 T 06-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GTHT12_RS11565 1c04552dd4cef11ef58992694ba6e160 111 SUPERFAMILY SSF101386 4 104 2.78E-27 T 06-07-2017 GTHT12_RS11565 1c04552dd4cef11ef58992694ba6e160 111 PIRSF PIRSF029904 1 111 1.6E-54 T 06-07-2017 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD GTHT12_RS11565 1c04552dd4cef11ef58992694ba6e160 111 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 25 104 1.1E-18 T 06-07-2017 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core GTHT12_RS11565 1c04552dd4cef11ef58992694ba6e160 111 Gene3D G3DSA:1.10.287.1080 4 95 8.8E-19 T 06-07-2017 GTHT12_RS12870 ca514b00d57b985707dcd9a5b13dd367 116 SUPERFAMILY SSF46894 56 115 4.76E-5 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GTHT12_RS12870 ca514b00d57b985707dcd9a5b13dd367 116 Pfam PF08281 Sigma-70, region 4 75 113 3.4E-6 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS12870 ca514b00d57b985707dcd9a5b13dd367 116 Gene3D G3DSA:1.10.10.10 63 114 3.2E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12965 4cc3783e94979496a21b8c0c4621ad3c 86 ProDom PD060869 YQFT IG BH1387 1 74 2.0E-34 T 06-07-2017 IPR020277 Protein of unknown function DUF2624 GTHT12_RS12965 4cc3783e94979496a21b8c0c4621ad3c 86 Pfam PF11116 Protein of unknown function (DUF2624) 1 83 4.1E-34 T 06-07-2017 IPR020277 Protein of unknown function DUF2624 GTHT12_RS14110 e0d73e6ab4a5194153dbc439fedf2334 174 Pfam PF01625 Peptide methionine sulfoxide reductase 3 154 2.3E-61 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 GTHT12_RS14110 e0d73e6ab4a5194153dbc439fedf2334 174 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 1 160 37.205 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 GTHT12_RS14110 e0d73e6ab4a5194153dbc439fedf2334 174 Gene3D G3DSA:3.30.1060.10 1 154 3.9E-70 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 GTHT12_RS14110 e0d73e6ab4a5194153dbc439fedf2334 174 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 2 153 8.8E-63 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 GTHT12_RS14110 e0d73e6ab4a5194153dbc439fedf2334 174 SUPERFAMILY SSF55068 1 165 1.7E-72 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 GTHT12_RS15655 326640bd328e75bd1b96ac8533ae38e5 125 Gene3D G3DSA:3.40.30.10 1 117 1.3E-42 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS15655 326640bd328e75bd1b96ac8533ae38e5 125 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 116 1.8E-31 T 06-07-2017 IPR006504 Transcriptional regulator Spx/MgsR GTHT12_RS15655 326640bd328e75bd1b96ac8533ae38e5 125 SUPERFAMILY SSF52833 3 117 8.95E-37 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS15655 326640bd328e75bd1b96ac8533ae38e5 125 Pfam PF03960 ArsC family 6 116 6.1E-14 T 06-07-2017 IPR006660 Arsenate reductase-like GTHT12_RS16345 a94a42d2ef020d77294a14996266d17e 917 Gene3D G3DSA:3.90.550.10 38 236 2.0E-47 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS16345 a94a42d2ef020d77294a14996266d17e 917 Pfam PF00535 Glycosyl transferase family 2 42 205 1.5E-35 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 GTHT12_RS16345 a94a42d2ef020d77294a14996266d17e 917 SUPERFAMILY SSF53756 688 915 6.8E-17 T 06-07-2017 GTHT12_RS16345 a94a42d2ef020d77294a14996266d17e 917 SUPERFAMILY SSF53448 39 267 8.53E-51 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS16345 a94a42d2ef020d77294a14996266d17e 917 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 562 917 1.7E-114 T 06-07-2017 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 GTHT12_RS00575 8dbd355d02f058aed084dcc9a756f7f4 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS00575 8dbd355d02f058aed084dcc9a756f7f4 216 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 60 73 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS00575 8dbd355d02f058aed084dcc9a756f7f4 216 Gene3D G3DSA:1.10.1740.10 13 127 5.2E-23 T 06-07-2017 GTHT12_RS00575 8dbd355d02f058aed084dcc9a756f7f4 216 SUPERFAMILY SSF88659 123 210 4.58E-12 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS00575 8dbd355d02f058aed084dcc9a756f7f4 216 Pfam PF08281 Sigma-70, region 4 159 205 7.5E-10 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS00575 8dbd355d02f058aed084dcc9a756f7f4 216 PIRSF PIRSF002939 2 216 2.2E-109 T 06-07-2017 IPR016371 RNA polymerase sigma-H factor GO:0003677|GO:0006351|GO:0016987 GTHT12_RS00575 8dbd355d02f058aed084dcc9a756f7f4 216 TIGRFAM TIGR02859 spore_sigH: RNA polymerase sigma-H factor 13 210 8.9E-112 T 06-07-2017 IPR014218 RNA polymerase sigma-H type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS00575 8dbd355d02f058aed084dcc9a756f7f4 216 SMART SM00421 160 209 0.0098 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS00575 8dbd355d02f058aed084dcc9a756f7f4 216 SUPERFAMILY SSF88946 18 105 2.88E-22 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS00575 8dbd355d02f058aed084dcc9a756f7f4 216 Gene3D G3DSA:1.10.10.10 142 206 1.2E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS00575 8dbd355d02f058aed084dcc9a756f7f4 216 Pfam PF04542 Sigma-70 region 2 36 105 1.8E-13 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS00575 8dbd355d02f058aed084dcc9a756f7f4 216 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 209 1.4E-27 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS12100 1cffc45479ed32a6903615986475c6bd 154 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 13 149 1.1E-60 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GTHT12_RS12100 1cffc45479ed32a6903615986475c6bd 154 Gene3D G3DSA:3.40.50.960 3 153 3.4E-69 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GTHT12_RS12100 1cffc45479ed32a6903615986475c6bd 154 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 8 153 31.709 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GTHT12_RS12100 1cffc45479ed32a6903615986475c6bd 154 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 12 150 2.4E-60 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GTHT12_RS12100 1cffc45479ed32a6903615986475c6bd 154 SUPERFAMILY SSF52121 3 153 7.72E-64 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GTHT12_RS13530 ae1d24707b57c4db296f9ed6a9b80c1e 342 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 342 1.3E-151 T 06-07-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 GTHT12_RS13530 ae1d24707b57c4db296f9ed6a9b80c1e 342 SUPERFAMILY SSF111337 1 342 2.09E-143 T 06-07-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 GTHT12_RS13530 ae1d24707b57c4db296f9ed6a9b80c1e 342 Pfam PF02547 Queuosine biosynthesis protein 4 341 6.5E-144 T 06-07-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 GTHT12_RS13530 ae1d24707b57c4db296f9ed6a9b80c1e 342 Gene3D G3DSA:2.40.10.240 64 142 2.6E-30 T 06-07-2017 GTHT12_RS13530 ae1d24707b57c4db296f9ed6a9b80c1e 342 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 342 47.864 T 06-07-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 GTHT12_RS13530 ae1d24707b57c4db296f9ed6a9b80c1e 342 Gene3D G3DSA:3.40.1780.10 1 62 4.6E-105 T 06-07-2017 GTHT12_RS13530 ae1d24707b57c4db296f9ed6a9b80c1e 342 Gene3D G3DSA:3.40.1780.10 178 342 4.6E-105 T 06-07-2017 GTHT12_RS15595 8f56561a1085c6dc1b611df5c3a20d96 437 SUPERFAMILY SSF101960 12 435 2.09E-121 T 06-07-2017 GTHT12_RS15595 8f56561a1085c6dc1b611df5c3a20d96 437 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 152 427 2.0E-76 T 06-07-2017 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 GTHT12_RS15595 8f56561a1085c6dc1b611df5c3a20d96 437 Pfam PF01458 Uncharacterized protein family (UPF0051) 186 410 2.6E-61 T 06-07-2017 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 GTHT12_RS11820 059d88c193020f0728186cc41693a71d 231 PIRSF PIRSF016933 1 219 5.1E-89 T 06-07-2017 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 GTHT12_RS11820 059d88c193020f0728186cc41693a71d 231 Pfam PF13367 Protease prsW family 28 194 1.1E-33 T 06-07-2017 IPR026898 Protease PrsW GO:0008233 GTHT12_RS06885 9129a7618ce1ed590940c2a300d64865 217 Pfam PF00239 Resolvase, N terminal domain 3 147 4.7E-28 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 GTHT12_RS06885 9129a7618ce1ed590940c2a300d64865 217 SUPERFAMILY SSF53041 1 149 1.7E-28 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 GTHT12_RS06885 9129a7618ce1ed590940c2a300d64865 217 SMART SM00857 3 149 1.6E-37 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 GTHT12_RS06885 9129a7618ce1ed590940c2a300d64865 217 Gene3D G3DSA:3.40.50.1390 1 131 6.3E-23 T 06-07-2017 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 GTHT12_RS10540 894b9564e267210c569572c77454add3 454 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 06-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 GTHT12_RS10540 894b9564e267210c569572c77454add3 454 Gene3D G3DSA:3.30.1360.60 4 82 1.8E-24 T 06-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 GTHT12_RS10540 894b9564e267210c569572c77454add3 454 Pfam PF00367 phosphotransferase system, EIIB 10 42 4.1E-14 T 06-07-2017 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 GTHT12_RS10540 894b9564e267210c569572c77454add3 454 SUPERFAMILY SSF55604 7 82 3.53E-18 T 06-07-2017 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 GTHT12_RS10540 894b9564e267210c569572c77454add3 454 Pfam PF02378 Phosphotransferase system, EIIC 121 389 2.8E-34 T 06-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 GTHT12_RS04520 265143bc64a09a951e515c99b035177b 337 SUPERFAMILY SSF53901 54 309 1.75E-21 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS04520 265143bc64a09a951e515c99b035177b 337 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 4 332 1.6E-156 T 06-07-2017 IPR010894 Stage V sporulation AD GTHT12_RS04520 265143bc64a09a951e515c99b035177b 337 PIRSF PIRSF011570 1 335 1.8E-157 T 06-07-2017 IPR010894 Stage V sporulation AD GTHT12_RS04520 265143bc64a09a951e515c99b035177b 337 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 5 332 2.1E-153 T 06-07-2017 IPR010894 Stage V sporulation AD GTHT12_RS04520 265143bc64a09a951e515c99b035177b 337 Gene3D G3DSA:3.40.47.10 57 173 1.2E-8 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS00290 6774d4965768c3b0a3d414571f3a3bc2 1177 Pfam PF00270 DEAD/DEAH box helicase 625 784 1.4E-17 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 GTHT12_RS00290 6774d4965768c3b0a3d414571f3a3bc2 1177 Pfam PF03461 TRCF domain 1026 1116 4.5E-29 T 06-07-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 GTHT12_RS00290 6774d4965768c3b0a3d414571f3a3bc2 1177 SUPERFAMILY SSF141259 490 568 7.85E-27 T 06-07-2017 IPR003711 CarD-like/TRCF domain GTHT12_RS00290 6774d4965768c3b0a3d414571f3a3bc2 1177 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 37 1119 30.005 T 06-07-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 GTHT12_RS00290 6774d4965768c3b0a3d414571f3a3bc2 1177 SMART SM00490 846 930 1.2E-19 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS00290 6774d4965768c3b0a3d414571f3a3bc2 1177 Gene3D G3DSA:3.30.2060.10 142 219 9.5E-14 T 06-07-2017 GTHT12_RS00290 6774d4965768c3b0a3d414571f3a3bc2 1177 SMART SM01058 499 596 9.9E-51 T 06-07-2017 IPR003711 CarD-like/TRCF domain GTHT12_RS00290 6774d4965768c3b0a3d414571f3a3bc2 1177 SUPERFAMILY SSF52540 802 1008 2.72E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00290 6774d4965768c3b0a3d414571f3a3bc2 1177 Gene3D G3DSA:3.40.50.300 607 806 1.2E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00290 6774d4965768c3b0a3d414571f3a3bc2 1177 SUPERFAMILY SSF52540 15 368 8.67E-89 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00290 6774d4965768c3b0a3d414571f3a3bc2 1177 SMART SM00982 1024 1123 1.8E-40 T 06-07-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 GTHT12_RS00290 6774d4965768c3b0a3d414571f3a3bc2 1177 Pfam PF02559 CarD-like/TRCF domain 500 595 3.7E-31 T 06-07-2017 IPR003711 CarD-like/TRCF domain GTHT12_RS00290 6774d4965768c3b0a3d414571f3a3bc2 1177 Gene3D G3DSA:3.40.50.300 15 82 2.5E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00290 6774d4965768c3b0a3d414571f3a3bc2 1177 Gene3D G3DSA:3.40.50.300 255 310 2.5E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00290 6774d4965768c3b0a3d414571f3a3bc2 1177 Gene3D G3DSA:3.40.50.300 819 976 3.7E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00290 6774d4965768c3b0a3d414571f3a3bc2 1177 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 158 1098 0.0 T 06-07-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 GTHT12_RS00290 6774d4965768c3b0a3d414571f3a3bc2 1177 SUPERFAMILY SSF52540 377 490 4.78E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00290 6774d4965768c3b0a3d414571f3a3bc2 1177 Pfam PF00271 Helicase conserved C-terminal domain 825 929 3.6E-18 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS00290 6774d4965768c3b0a3d414571f3a3bc2 1177 SMART SM00487 620 810 2.7E-36 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain GTHT12_RS00290 6774d4965768c3b0a3d414571f3a3bc2 1177 SUPERFAMILY SSF52540 543 803 1.48E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00290 6774d4965768c3b0a3d414571f3a3bc2 1177 SUPERFAMILY SSF143517 1014 1168 7.98E-38 T 06-07-2017 GTHT12_RS01920 e2a1e524e47dc9718c4ffb868afb1686 589 Gene3D G3DSA:3.30.2010.10 341 421 7.7E-14 T 06-07-2017 GTHT12_RS01920 e2a1e524e47dc9718c4ffb868afb1686 589 Pfam PF01435 Peptidase family M48 345 566 9.5E-17 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 GTHT12_RS13110 02785580a313babbadf9c2b3f6f5b28b 258 Gene3D G3DSA:3.40.1280.10 73 250 4.1E-61 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal GTHT12_RS13110 02785580a313babbadf9c2b3f6f5b28b 258 SUPERFAMILY SSF75217 72 248 2.97E-53 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases GTHT12_RS13110 02785580a313babbadf9c2b3f6f5b28b 258 Gene3D G3DSA:2.40.240.20 2 70 1.3E-24 T 06-07-2017 GTHT12_RS13110 02785580a313babbadf9c2b3f6f5b28b 258 SUPERFAMILY SSF88697 2 68 3.73E-16 T 06-07-2017 IPR015947 PUA-like domain GTHT12_RS13110 02785580a313babbadf9c2b3f6f5b28b 258 Pfam PF04452 RNA methyltransferase 17 244 3.9E-71 T 06-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GTHT12_RS13110 02785580a313babbadf9c2b3f6f5b28b 258 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 7 246 1.9E-66 T 06-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GTHT12_RS13110 02785580a313babbadf9c2b3f6f5b28b 258 PIRSF PIRSF015601 1 249 5.4E-62 T 06-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GTHT12_RS11255 14422abcfd9a8d9cd3b00905d9a6c401 483 SUPERFAMILY SSF53720 28 429 2.62E-10 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GTHT12_RS11255 14422abcfd9a8d9cd3b00905d9a6c401 483 PIRSF PIRSF009414 11 483 7.5E-87 T 06-07-2017 IPR008670 Acyl-CoA reductase, LuxC GO:0003995|GO:0008218|GO:0055114 KEGG: 00073+1.2.1.50|MetaCyc: PWY-7723 GTHT12_RS11255 14422abcfd9a8d9cd3b00905d9a6c401 483 Pfam PF05893 Acyl-CoA reductase (LuxC) 58 463 9.9E-97 T 06-07-2017 IPR008670 Acyl-CoA reductase, LuxC GO:0003995|GO:0008218|GO:0055114 KEGG: 00073+1.2.1.50|MetaCyc: PWY-7723 GTHT12_RS16815 bea453d7abd84565e4ab8e1d29ddb2f0 450 Pfam PF02386 Cation transport protein 42 428 9.9E-60 T 06-07-2017 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 GTHT12_RS05775 11b572c6fd1904721d77bd22ca7f7058 202 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 182 8.6E-57 T 06-07-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS05775 11b572c6fd1904721d77bd22ca7f7058 202 PIRSF PIRSF004553 1 184 8.1E-52 T 06-07-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 GTHT12_RS05775 11b572c6fd1904721d77bd22ca7f7058 202 Gene3D G3DSA:3.40.50.150 1 185 4.0E-60 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS05775 11b572c6fd1904721d77bd22ca7f7058 202 SUPERFAMILY SSF53335 1 181 4.95E-51 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS05775 11b572c6fd1904721d77bd22ca7f7058 202 Pfam PF03602 Conserved hypothetical protein 95 1 181 5.9E-59 T 06-07-2017 GTHT12_RS14215 ec58b20b55364fb43234ca40b35b7491 234 SUPERFAMILY SSF46894 129 229 1.5E-33 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GTHT12_RS14215 ec58b20b55364fb43234ca40b35b7491 234 SMART SM00862 152 228 2.0E-32 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS14215 ec58b20b55364fb43234ca40b35b7491 234 SUPERFAMILY SSF52172 2 128 1.17E-43 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS14215 ec58b20b55364fb43234ca40b35b7491 234 Pfam PF00072 Response regulator receiver domain 5 114 3.8E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS14215 ec58b20b55364fb43234ca40b35b7491 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 228 3.8E-31 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS14215 ec58b20b55364fb43234ca40b35b7491 234 SMART SM00448 3 114 1.6E-46 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS14215 ec58b20b55364fb43234ca40b35b7491 234 Gene3D G3DSA:1.10.10.10 130 231 9.0E-40 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS14215 ec58b20b55364fb43234ca40b35b7491 234 Gene3D G3DSA:3.40.50.2300 1 124 2.5E-43 T 06-07-2017 GTHT12_RS05935 0aaf924559ed72664a142aaaf252987e 80 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 3 75 3.5E-28 T 06-07-2017 IPR014238 Sporulation protein YlmC/YmxH GTHT12_RS05935 0aaf924559ed72664a142aaaf252987e 80 Pfam PF05239 PRC-barrel domain 2 75 3.4E-15 T 06-07-2017 IPR027275 PRC-barrel domain GTHT12_RS05935 0aaf924559ed72664a142aaaf252987e 80 SUPERFAMILY SSF50346 1 74 1.75E-15 T 06-07-2017 IPR011033 PRC-barrel-like GTHT12_RS05935 0aaf924559ed72664a142aaaf252987e 80 Gene3D G3DSA:2.30.30.240 2 77 6.9E-28 T 06-07-2017 GTHT12_RS06705 ff3696fbce7f72a7dba627f6637e635e 192 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1 187 1.7E-67 T 06-07-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 GTHT12_RS06705 ff3696fbce7f72a7dba627f6637e635e 192 PIRSF PIRSF000847 1 192 3.4E-54 T 06-07-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 GTHT12_RS06705 ff3696fbce7f72a7dba627f6637e635e 192 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 81 2.6E-18 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 GTHT12_RS06705 ff3696fbce7f72a7dba627f6637e635e 192 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 59 81 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 GTHT12_RS13020 d01a03e7d7dcd8af9489ce6639db8988 266 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 6 266 59.547 T 06-07-2017 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein GTHT12_RS13020 d01a03e7d7dcd8af9489ce6639db8988 266 Pfam PF03618 Kinase/pyrophosphorylase 6 261 1.4E-96 T 06-07-2017 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 GTHT12_RS10765 ff9138e0bd994e4661886ddfa568eccd 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 257 1.5E-75 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 GTHT12_RS10765 ff9138e0bd994e4661886ddfa568eccd 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 GTHT12_RS10765 ff9138e0bd994e4661886ddfa568eccd 258 Gene3D G3DSA:3.90.226.10 3 199 2.6E-69 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS10765 ff9138e0bd994e4661886ddfa568eccd 258 Gene3D G3DSA:1.10.12.10 200 258 8.5E-26 T 06-07-2017 IPR014748 Crontonase, C-terminal GTHT12_RS10765 ff9138e0bd994e4661886ddfa568eccd 258 SUPERFAMILY SSF52096 6 257 2.06E-86 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS07690 23204c686f4b071c68509f973af8d264 221 Gene3D G3DSA:1.10.3720.10 12 220 2.7E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS07690 23204c686f4b071c68509f973af8d264 221 SUPERFAMILY SSF161098 12 206 7.06E-43 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS07690 23204c686f4b071c68509f973af8d264 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 221 5.1E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS11125 1fa7d3c4df9977da469ec2c6e2307b78 384 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 116 2.9E-25 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 GTHT12_RS11125 1fa7d3c4df9977da469ec2c6e2307b78 384 Gene3D G3DSA:3.30.360.10 143 281 2.5E-28 T 06-07-2017 GTHT12_RS11125 1fa7d3c4df9977da469ec2c6e2307b78 384 Gene3D G3DSA:3.30.360.10 327 383 2.5E-28 T 06-07-2017 GTHT12_RS11125 1fa7d3c4df9977da469ec2c6e2307b78 384 Gene3D G3DSA:3.40.50.720 1 142 1.7E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS11125 1fa7d3c4df9977da469ec2c6e2307b78 384 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 213 2.5E-5 T 06-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 GTHT12_RS11125 1fa7d3c4df9977da469ec2c6e2307b78 384 SUPERFAMILY SSF51735 4 138 1.67E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS11125 1fa7d3c4df9977da469ec2c6e2307b78 384 SUPERFAMILY SSF55347 129 327 1.37E-28 T 06-07-2017 GTHT12_RS16485 da8ccbd179e0037a5f263b5d8142734e 273 Gene3D G3DSA:1.10.3720.10 3 258 4.6E-58 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS16485 da8ccbd179e0037a5f263b5d8142734e 273 SUPERFAMILY SSF161098 3 273 1.78E-67 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS16485 da8ccbd179e0037a5f263b5d8142734e 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 266 9.6E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS14165 aa4799416886742c4526a210e96fefc5 313 SUPERFAMILY SSF52540 128 273 3.88E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS14165 aa4799416886742c4526a210e96fefc5 313 SMART SM00382 160 307 0.0022 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS14165 aa4799416886742c4526a210e96fefc5 313 Pfam PF07319 Primosomal protein DnaI N-terminus 1 98 4.4E-30 T 06-07-2017 IPR009928 Primosomal DnaI, N-terminal GTHT12_RS14165 aa4799416886742c4526a210e96fefc5 313 Gene3D G3DSA:3.40.50.300 110 299 2.2E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS14165 aa4799416886742c4526a210e96fefc5 313 Pfam PF01695 IstB-like ATP binding protein 159 271 1.3E-11 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 GTHT12_RS12775 3ca0fa14fcc67c864cb4d61020f9c5a3 98 SUPERFAMILY SSF54523 6 91 7.06E-16 T 06-07-2017 GTHT12_RS12775 3ca0fa14fcc67c864cb4d61020f9c5a3 98 Gene3D G3DSA:3.30.700.10 6 65 5.8E-5 T 06-07-2017 GTHT12_RS12775 3ca0fa14fcc67c864cb4d61020f9c5a3 98 Pfam PF13633 Prokaryotic N-terminal methylation site 3 28 6.0E-8 T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site GTHT12_RS12775 3ca0fa14fcc67c864cb4d61020f9c5a3 98 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 4 24 - T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site GTHT12_RS12775 3ca0fa14fcc67c864cb4d61020f9c5a3 98 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 26 1.3E-8 T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site GTHT12_RS12775 3ca0fa14fcc67c864cb4d61020f9c5a3 98 PIRSF PIRSF029928 1 96 8.4E-35 T 06-07-2017 IPR016940 ComG operon protein C GO:0030420 GTHT12_RS14095 ecec801944305a04f5e1e8567efd35c5 804 Pfam PF03483 B3/4 domain 222 394 1.2E-68 T 06-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 GTHT12_RS14095 ecec801944305a04f5e1e8567efd35c5 804 Pfam PF01588 Putative tRNA binding domain 46 152 6.7E-27 T 06-07-2017 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 GTHT12_RS14095 ecec801944305a04f5e1e8567efd35c5 804 Gene3D G3DSA:3.50.40.10 207 403 1.4E-84 T 06-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 GTHT12_RS14095 ecec801944305a04f5e1e8567efd35c5 804 Gene3D G3DSA:3.30.56.20 410 483 5.2E-25 T 06-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 GTHT12_RS14095 ecec801944305a04f5e1e8567efd35c5 804 SUPERFAMILY SSF46955 411 483 1.74E-19 T 06-07-2017 IPR009061 Putative DNA-binding domain GTHT12_RS14095 ecec801944305a04f5e1e8567efd35c5 804 SUPERFAMILY SSF54991 705 803 2.22E-33 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 GTHT12_RS14095 ecec801944305a04f5e1e8567efd35c5 804 SMART SM00874 411 479 9.1E-28 T 06-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 GTHT12_RS14095 ecec801944305a04f5e1e8567efd35c5 804 Pfam PF03147 Ferredoxin-fold anticodon binding domain 710 803 5.2E-31 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 GTHT12_RS14095 ecec801944305a04f5e1e8567efd35c5 804 Gene3D G3DSA:3.30.70.380 712 803 3.9E-33 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 GTHT12_RS14095 ecec801944305a04f5e1e8567efd35c5 804 SUPERFAMILY SSF50249 37 199 1.62E-49 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS14095 ecec801944305a04f5e1e8567efd35c5 804 SUPERFAMILY SSF56037 209 406 3.92E-74 T 06-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 GTHT12_RS14095 ecec801944305a04f5e1e8567efd35c5 804 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 797 47.98 T 06-07-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 GTHT12_RS14095 ecec801944305a04f5e1e8567efd35c5 804 SUPERFAMILY SSF55681 475 696 3.73E-54 T 06-07-2017 GTHT12_RS14095 ecec801944305a04f5e1e8567efd35c5 804 Pfam PF03484 tRNA synthetase B5 domain 414 479 2.4E-18 T 06-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 GTHT12_RS14095 ecec801944305a04f5e1e8567efd35c5 804 Gene3D G3DSA:3.30.56.10 1 39 3.7E-24 T 06-07-2017 GTHT12_RS14095 ecec801944305a04f5e1e8567efd35c5 804 Gene3D G3DSA:3.30.56.10 162 191 3.7E-24 T 06-07-2017 GTHT12_RS14095 ecec801944305a04f5e1e8567efd35c5 804 SMART SM00873 221 394 4.0E-93 T 06-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 GTHT12_RS14095 ecec801944305a04f5e1e8567efd35c5 804 SMART SM00896 710 803 9.5E-49 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 GTHT12_RS14095 ecec801944305a04f5e1e8567efd35c5 804 Gene3D G3DSA:3.30.930.10 496 698 1.0E-68 T 06-07-2017 GTHT12_RS14095 ecec801944305a04f5e1e8567efd35c5 804 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 803 7.2E-275 T 06-07-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 GTHT12_RS14095 ecec801944305a04f5e1e8567efd35c5 804 Gene3D G3DSA:2.40.50.140 43 160 1.1E-48 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS17835 9b6545c74c36c48a2d52717a47ce71c2 211 SUPERFAMILY SSF52218 1 210 1.17E-53 T 06-07-2017 IPR029039 Flavoprotein-like domain GTHT12_RS17835 9b6545c74c36c48a2d52717a47ce71c2 211 Pfam PF02525 Flavodoxin-like fold 3 206 7.9E-48 T 06-07-2017 IPR003680 Flavodoxin-like fold GTHT12_RS17835 9b6545c74c36c48a2d52717a47ce71c2 211 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 211 29.125 T 06-07-2017 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 GTHT12_RS17835 9b6545c74c36c48a2d52717a47ce71c2 211 Gene3D G3DSA:3.40.50.360 1 210 3.1E-69 T 06-07-2017 IPR029039 Flavoprotein-like domain GTHT12_RS03520 87f4df937e6cd7ba7a53dbe2cfeded33 341 SUPERFAMILY SSF69572 2 333 5.76E-80 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 GTHT12_RS03520 87f4df937e6cd7ba7a53dbe2cfeded33 341 Gene3D G3DSA:3.40.50.720 2 246 5.5E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS03520 87f4df937e6cd7ba7a53dbe2cfeded33 341 Pfam PF00899 ThiF family 5 243 7.3E-55 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 GTHT12_RS02300 265ffa236f89c1e233bc46477c8a1ccf 168 Gene3D G3DSA:3.10.20.30 7 80 7.3E-27 T 06-07-2017 IPR012675 Beta-grasp domain GTHT12_RS02300 265ffa236f89c1e233bc46477c8a1ccf 168 Pfam PF01799 [2Fe-2S] binding domain 79 148 7.5E-27 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 GTHT12_RS02300 265ffa236f89c1e233bc46477c8a1ccf 168 Gene3D G3DSA:1.10.150.120 81 157 2.8E-29 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 GTHT12_RS02300 265ffa236f89c1e233bc46477c8a1ccf 168 SUPERFAMILY SSF47741 79 157 5.5E-30 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 GTHT12_RS02300 265ffa236f89c1e233bc46477c8a1ccf 168 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 12 59 1.1E-5 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 GTHT12_RS02300 265ffa236f89c1e233bc46477c8a1ccf 168 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 45 53 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 GTHT12_RS02300 265ffa236f89c1e233bc46477c8a1ccf 168 SUPERFAMILY SSF54292 10 93 2.36E-23 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 GTHT12_RS02235 0496ff74baec5f5e6784157d87390aa1 152 Pfam PF13581 Histidine kinase-like ATPase domain 20 126 2.8E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS02235 0496ff74baec5f5e6784157d87390aa1 152 SUPERFAMILY SSF55874 20 118 8.63E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS09195 5fb2b017e02b38de8709f5f4b3c553bb 282 SUPERFAMILY SSF56281 28 261 1.7E-44 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS09195 5fb2b017e02b38de8709f5f4b3c553bb 282 Gene3D G3DSA:3.60.15.10 32 260 8.4E-40 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS09195 5fb2b017e02b38de8709f5f4b3c553bb 282 SMART SM00849 39 249 6.2E-34 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS09195 5fb2b017e02b38de8709f5f4b3c553bb 282 Pfam PF00753 Metallo-beta-lactamase superfamily 39 249 2.4E-32 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS15915 542608ec6c9d1ad86f26dc8dc70011d9 435 PIRSF PIRSF000774 1 432 6.0E-136 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS15915 542608ec6c9d1ad86f26dc8dc70011d9 435 Pfam PF04963 Sigma-54 factor, core binding domain 70 257 2.5E-54 T 06-07-2017 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 GTHT12_RS15915 542608ec6c9d1ad86f26dc8dc70011d9 435 Pfam PF04552 Sigma-54, DNA binding domain 271 430 3.0E-58 T 06-07-2017 IPR007634 RNA polymerase sigma factor 54, DNA-binding GTHT12_RS15915 542608ec6c9d1ad86f26dc8dc70011d9 435 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 5 49 1.5E-13 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS15915 542608ec6c9d1ad86f26dc8dc70011d9 435 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 9 429 2.7E-135 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS15915 542608ec6c9d1ad86f26dc8dc70011d9 435 Gene3D G3DSA:1.10.260.40 319 342 1.3E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS15915 542608ec6c9d1ad86f26dc8dc70011d9 435 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 318 337 - T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS15915 542608ec6c9d1ad86f26dc8dc70011d9 435 PRINTS PR00045 Sigma-54 factor signature 346 357 5.3E-26 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS15915 542608ec6c9d1ad86f26dc8dc70011d9 435 PRINTS PR00045 Sigma-54 factor signature 142 159 5.3E-26 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS15915 542608ec6c9d1ad86f26dc8dc70011d9 435 PRINTS PR00045 Sigma-54 factor signature 330 342 5.3E-26 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS15915 542608ec6c9d1ad86f26dc8dc70011d9 435 PRINTS PR00045 Sigma-54 factor signature 405 423 5.3E-26 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS15915 542608ec6c9d1ad86f26dc8dc70011d9 435 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 410 417 - T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS03530 74915e3085307a26027301d23c0bd59e 70 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 8 62 3.1E-22 T 06-07-2017 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 GTHT12_RS03530 74915e3085307a26027301d23c0bd59e 70 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 41 55 - T 06-07-2017 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 GTHT12_RS03530 74915e3085307a26027301d23c0bd59e 70 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 23 32 - T 06-07-2017 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 GTHT12_RS08435 14dc0d93949904e0f2e89efb0f0b6428 220 SUPERFAMILY SSF51569 6 205 2.75E-61 T 06-07-2017 GTHT12_RS08435 14dc0d93949904e0f2e89efb0f0b6428 220 Pfam PF01081 KDPG and KHG aldolase 9 183 8.8E-39 T 06-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 GTHT12_RS08435 14dc0d93949904e0f2e89efb0f0b6428 220 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 8 206 1.7E-51 T 06-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 GTHT12_RS08435 14dc0d93949904e0f2e89efb0f0b6428 220 Gene3D G3DSA:3.20.20.70 4 213 2.1E-73 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS13270 130f5140a4ef214d1ffb6081d68c5463 421 Gene3D G3DSA:1.10.3860.10 2 407 2.7E-137 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS13270 130f5140a4ef214d1ffb6081d68c5463 421 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 4.6E-38 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS13270 130f5140a4ef214d1ffb6081d68c5463 421 PRINTS PR00173 Glutamate-aspartate symporter signature 74 99 4.6E-38 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS13270 130f5140a4ef214d1ffb6081d68c5463 421 PRINTS PR00173 Glutamate-aspartate symporter signature 328 347 4.6E-38 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS13270 130f5140a4ef214d1ffb6081d68c5463 421 PRINTS PR00173 Glutamate-aspartate symporter signature 146 168 4.6E-38 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS13270 130f5140a4ef214d1ffb6081d68c5463 421 PRINTS PR00173 Glutamate-aspartate symporter signature 193 212 4.6E-38 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS13270 130f5140a4ef214d1ffb6081d68c5463 421 PRINTS PR00173 Glutamate-aspartate symporter signature 293 319 4.6E-38 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS13270 130f5140a4ef214d1ffb6081d68c5463 421 PRINTS PR00173 Glutamate-aspartate symporter signature 355 375 4.6E-38 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS13270 130f5140a4ef214d1ffb6081d68c5463 421 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 36 51 - T 06-07-2017 IPR018107 Sodium:dicarboxylate symporter, conserved site GTHT12_RS13270 130f5140a4ef214d1ffb6081d68c5463 421 Pfam PF00375 Sodium:dicarboxylate symporter family 6 401 3.1E-123 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS13270 130f5140a4ef214d1ffb6081d68c5463 421 SUPERFAMILY SSF118215 6 402 1.01E-125 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS13270 130f5140a4ef214d1ffb6081d68c5463 421 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 296 319 - T 06-07-2017 IPR018107 Sodium:dicarboxylate symporter, conserved site GTHT12_RS14930 aa8e149f58214f70289209e1a3fdc844 343 SUPERFAMILY SSF53448 18 225 3.21E-38 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS14930 aa8e149f58214f70289209e1a3fdc844 343 SUPERFAMILY SSF53448 286 303 3.21E-38 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS14930 aa8e149f58214f70289209e1a3fdc844 343 Pfam PF00483 Nucleotidyl transferase 18 147 6.2E-7 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 GTHT12_RS14930 aa8e149f58214f70289209e1a3fdc844 343 SUPERFAMILY SSF51161 256 322 7.35E-16 T 06-07-2017 IPR011004 Trimeric LpxA-like GTHT12_RS14930 aa8e149f58214f70289209e1a3fdc844 343 Gene3D G3DSA:3.90.550.10 157 232 1.7E-15 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS14930 aa8e149f58214f70289209e1a3fdc844 343 Gene3D G3DSA:3.90.550.10 17 149 3.4E-13 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS14930 aa8e149f58214f70289209e1a3fdc844 343 Gene3D G3DSA:3.90.550.10 269 312 1.7E-15 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS14930 aa8e149f58214f70289209e1a3fdc844 343 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 289 323 2.0E-6 T 06-07-2017 IPR001451 Hexapeptide repeat GTHT12_RS11275 9a5e2c2a014935d59769a7dc2e291d8f 298 SUPERFAMILY SSF161098 65 226 1.16E-11 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS11275 9a5e2c2a014935d59769a7dc2e291d8f 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 281 3.3E-8 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS11275 9a5e2c2a014935d59769a7dc2e291d8f 298 Gene3D G3DSA:1.10.3720.10 65 275 1.7E-10 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS10405 5f244065f231779e2efb1472f32d97ef 483 Gene3D G3DSA:3.40.50.10370 391 481 1.9E-44 T 06-07-2017 IPR029503 Phosphotransferase system EIIB component, mannitol-specific GO:0009401|GO:0022872 GTHT12_RS10405 5f244065f231779e2efb1472f32d97ef 483 Pfam PF02378 Phosphotransferase system, EIIC 24 283 1.9E-22 T 06-07-2017 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 GTHT12_RS10405 5f244065f231779e2efb1472f32d97ef 483 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 394 478 4.4E-13 T 06-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 GTHT12_RS10405 5f244065f231779e2efb1472f32d97ef 483 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 14 349 1.0E-186 T 06-07-2017 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 GTHT12_RS10405 5f244065f231779e2efb1472f32d97ef 483 SUPERFAMILY SSF52794 391 481 4.19E-28 T 06-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 GTHT12_RS10070 eb8d621f53c8cfce943d1d28eb5064a2 336 SMART SM00354 2 72 1.8E-37 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS10070 eb8d621f53c8cfce943d1d28eb5064a2 336 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 06-07-2017 GTHT12_RS10070 eb8d621f53c8cfce943d1d28eb5064a2 336 SUPERFAMILY SSF53822 62 331 3.08E-78 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS10070 eb8d621f53c8cfce943d1d28eb5064a2 336 Pfam PF13377 Periplasmic binding protein-like domain 170 329 2.3E-36 T 06-07-2017 GTHT12_RS10070 eb8d621f53c8cfce943d1d28eb5064a2 336 Gene3D G3DSA:1.10.260.40 3 54 1.4E-25 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS10070 eb8d621f53c8cfce943d1d28eb5064a2 336 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 8.3E-6 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS10070 eb8d621f53c8cfce943d1d28eb5064a2 336 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 8.3E-6 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS10070 eb8d621f53c8cfce943d1d28eb5064a2 336 Gene3D G3DSA:3.40.50.2300 55 172 1.0E-44 T 06-07-2017 GTHT12_RS10070 eb8d621f53c8cfce943d1d28eb5064a2 336 Gene3D G3DSA:3.40.50.2300 173 310 1.9E-45 T 06-07-2017 GTHT12_RS10070 eb8d621f53c8cfce943d1d28eb5064a2 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 2.1E-22 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS10070 eb8d621f53c8cfce943d1d28eb5064a2 336 SUPERFAMILY SSF47413 2 60 4.65E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS06535 122e24f97b9c216de1fb181468542690 383 SUPERFAMILY SSF54814 278 342 4.84E-17 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 GTHT12_RS06535 122e24f97b9c216de1fb181468542690 383 SUPERFAMILY SSF54814 199 276 2.62E-31 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 GTHT12_RS06535 122e24f97b9c216de1fb181468542690 383 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 341 9.4E-135 T 06-07-2017 IPR010213 Transcription termination factor NusA GO:0003723 GTHT12_RS06535 122e24f97b9c216de1fb181468542690 383 Pfam PF13184 NusA-like KH domain 229 296 7.0E-30 T 06-07-2017 IPR025249 KH domain, NusA-like GO:0003723 GTHT12_RS06535 122e24f97b9c216de1fb181468542690 383 Gene3D G3DSA:3.30.300.20 278 345 1.6E-34 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta GTHT12_RS06535 122e24f97b9c216de1fb181468542690 383 SUPERFAMILY SSF50249 132 198 2.34E-20 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS06535 122e24f97b9c216de1fb181468542690 383 SMART SM00316 133 199 6.0E-12 T 06-07-2017 IPR022967 RNA-binding domain, S1 GTHT12_RS06535 122e24f97b9c216de1fb181468542690 383 Gene3D G3DSA:2.40.50.140 136 197 5.9E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS06535 122e24f97b9c216de1fb181468542690 383 Pfam PF00575 S1 RNA binding domain 133 193 7.1E-13 T 06-07-2017 IPR003029 S1 domain GO:0003676 GTHT12_RS06535 122e24f97b9c216de1fb181468542690 383 Gene3D G3DSA:3.30.300.20 198 276 3.7E-37 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta GTHT12_RS06535 122e24f97b9c216de1fb181468542690 383 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 380 30.91 T 06-07-2017 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 GTHT12_RS06535 122e24f97b9c216de1fb181468542690 383 SMART SM00322 300 381 1.4 T 06-07-2017 IPR004087 K Homology domain GO:0003676 GTHT12_RS06535 122e24f97b9c216de1fb181468542690 383 SMART SM00322 229 292 0.067 T 06-07-2017 IPR004087 K Homology domain GO:0003676 GTHT12_RS06535 122e24f97b9c216de1fb181468542690 383 SUPERFAMILY SSF69705 1 126 1.83E-45 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 GTHT12_RS06535 122e24f97b9c216de1fb181468542690 383 Gene3D G3DSA:3.30.1480.10 1 123 1.8E-49 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 GTHT12_RS06535 122e24f97b9c216de1fb181468542690 383 Pfam PF08529 NusA N-terminal domain 5 123 4.0E-46 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 GTHT12_RS09705 ecba8acfb5e00640c75d21ab78a535a7 73 Pfam PF04023 FeoA domain 1 73 3.8E-19 T 06-07-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 GTHT12_RS09705 ecba8acfb5e00640c75d21ab78a535a7 73 SMART SM00899 1 73 3.2E-17 T 06-07-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 GTHT12_RS09705 ecba8acfb5e00640c75d21ab78a535a7 73 SUPERFAMILY SSF50037 3 73 2.08E-16 T 06-07-2017 IPR008988 Transcriptional repressor, C-terminal GTHT12_RS00610 a7d1ad82eb873221e91fc8bc17088eb1 122 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 122 26.205 T 06-07-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00610 a7d1ad82eb873221e91fc8bc17088eb1 122 SUPERFAMILY SSF54736 52 122 8.55E-26 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like GTHT12_RS00610 a7d1ad82eb873221e91fc8bc17088eb1 122 Gene3D G3DSA:3.30.1390.10 51 122 1.9E-34 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like GTHT12_RS00610 a7d1ad82eb873221e91fc8bc17088eb1 122 SUPERFAMILY SSF48300 1 58 1.44E-17 T 06-07-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00610 a7d1ad82eb873221e91fc8bc17088eb1 122 TIGRFAM TIGR00855 L12: ribosomal protein bL12 2 122 1.2E-52 T 06-07-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00610 a7d1ad82eb873221e91fc8bc17088eb1 122 Gene3D G3DSA:1.20.5.710 1 50 4.9E-25 T 06-07-2017 GTHT12_RS00610 a7d1ad82eb873221e91fc8bc17088eb1 122 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 56 122 7.1E-32 T 06-07-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00610 a7d1ad82eb873221e91fc8bc17088eb1 122 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 57 122 3.0E-16 T 06-07-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00610 a7d1ad82eb873221e91fc8bc17088eb1 122 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 2 49 6.6E-22 T 06-07-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS14070 515f517408a05aae27686b1ae779ae6d 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 7.0E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS14070 515f517408a05aae27686b1ae779ae6d 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 7.0E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS14070 515f517408a05aae27686b1ae779ae6d 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 7.0E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS14070 515f517408a05aae27686b1ae779ae6d 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 7.0E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS14070 515f517408a05aae27686b1ae779ae6d 150 Gene3D G3DSA:1.10.10.10 35 147 3.0E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS14070 515f517408a05aae27686b1ae779ae6d 150 Pfam PF01047 MarR family 37 94 1.0E-15 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS14070 515f517408a05aae27686b1ae779ae6d 150 SMART SM00347 29 129 5.7E-23 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS14070 515f517408a05aae27686b1ae779ae6d 150 SUPERFAMILY SSF46785 33 146 3.91E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS01170 90c54eac86039b07cf451d8861c9ecd4 266 SMART SM00382 28 217 2.1E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS01170 90c54eac86039b07cf451d8861c9ecd4 266 SUPERFAMILY SSF52540 4 228 5.02E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01170 90c54eac86039b07cf451d8861c9ecd4 266 Pfam PF00005 ABC transporter 20 167 1.1E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS01170 90c54eac86039b07cf451d8861c9ecd4 266 Gene3D G3DSA:3.40.50.300 4 231 6.3E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01170 90c54eac86039b07cf451d8861c9ecd4 266 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS09700 ebc36d775aed2fd13aca44e14fdb9409 664 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 8 629 1.5E-193 T 06-07-2017 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 GTHT12_RS09700 ebc36d775aed2fd13aca44e14fdb9409 664 Gene3D G3DSA:3.40.50.300 4 165 1.9E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS09700 ebc36d775aed2fd13aca44e14fdb9409 664 Pfam PF02421 Ferrous iron transport protein B 4 155 2.2E-61 T 06-07-2017 IPR011619 Ferrous iron transport protein B, N-terminal GO:0005525|GO:0015093|GO:0015684|GO:0016021 GTHT12_RS09700 ebc36d775aed2fd13aca44e14fdb9409 664 Pfam PF07664 Ferrous iron transport protein B C terminus 451 503 8.1E-20 T 06-07-2017 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 GTHT12_RS09700 ebc36d775aed2fd13aca44e14fdb9409 664 Pfam PF07670 Nucleoside recognition 347 441 2.3E-15 T 06-07-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 GTHT12_RS09700 ebc36d775aed2fd13aca44e14fdb9409 664 Pfam PF07670 Nucleoside recognition 508 633 1.5E-34 T 06-07-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 GTHT12_RS09700 ebc36d775aed2fd13aca44e14fdb9409 664 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 25 43 1.4E-5 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS09700 ebc36d775aed2fd13aca44e14fdb9409 664 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 50 65 1.4E-5 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS09700 ebc36d775aed2fd13aca44e14fdb9409 664 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 1.4E-5 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS09700 ebc36d775aed2fd13aca44e14fdb9409 664 SUPERFAMILY SSF52540 4 163 3.58E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS15005 a53cb52963696e71d05242d6eb37649b 156 SUPERFAMILY SSF55729 5 149 1.06E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS15005 a53cb52963696e71d05242d6eb37649b 156 Pfam PF00583 Acetyltransferase (GNAT) family 74 146 2.4E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS15005 a53cb52963696e71d05242d6eb37649b 156 Gene3D G3DSA:3.40.630.30 5 147 2.1E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS10175 cee7534b36eada7f4a5bd7d8c82f7a33 253 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 06-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 GTHT12_RS10175 cee7534b36eada7f4a5bd7d8c82f7a33 253 SMART SM01134 73 233 4.2E-58 T 06-07-2017 GTHT12_RS10175 cee7534b36eada7f4a5bd7d8c82f7a33 253 Gene3D G3DSA:3.40.50.1360 76 216 3.7E-10 T 06-07-2017 GTHT12_RS10175 cee7534b36eada7f4a5bd7d8c82f7a33 253 SMART SM00420 6 58 5.6E-20 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 GTHT12_RS10175 cee7534b36eada7f4a5bd7d8c82f7a33 253 Gene3D G3DSA:1.10.10.10 5 59 1.6E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS10175 cee7534b36eada7f4a5bd7d8c82f7a33 253 SUPERFAMILY SSF46785 5 60 2.64E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS10175 cee7534b36eada7f4a5bd7d8c82f7a33 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.9E-6 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 GTHT12_RS10175 cee7534b36eada7f4a5bd7d8c82f7a33 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.9E-6 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 GTHT12_RS10175 cee7534b36eada7f4a5bd7d8c82f7a33 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 59 7.9E-17 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 GTHT12_RS10175 cee7534b36eada7f4a5bd7d8c82f7a33 253 Pfam PF00455 DeoR C terminal sensor domain 75 232 6.4E-45 T 06-07-2017 IPR014036 DeoR C-terminal sensor domain GTHT12_RS10175 cee7534b36eada7f4a5bd7d8c82f7a33 253 SUPERFAMILY SSF100950 76 234 2.51E-30 T 06-07-2017 GTHT12_RS14640 00a3f064dd4e99bd8c37e587a0c1e919 265 Pfam PF07285 Protein of unknown function (DUF1444) 1 264 7.4E-133 T 06-07-2017 IPR010838 Protein of unknown unction DUF1444 GTHT12_RS14640 00a3f064dd4e99bd8c37e587a0c1e919 265 PIRSF PIRSF012562 1 265 9.0E-130 T 06-07-2017 IPR010838 Protein of unknown unction DUF1444 GTHT12_RS14640 00a3f064dd4e99bd8c37e587a0c1e919 265 Hamap MF_01548 UPF0354 protein . 1 265 48.648 T 06-07-2017 IPR010838 Protein of unknown unction DUF1444 GTHT12_RS06130 1a21b50c1946c145879618d3b653ddc7 215 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 5 207 3.5E-53 T 06-07-2017 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 GTHT12_RS06130 1a21b50c1946c145879618d3b653ddc7 215 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 26 126 3.9E-16 T 06-07-2017 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 GTHT12_RS06130 1a21b50c1946c145879618d3b653ddc7 215 Gene3D G3DSA:3.40.50.10240 2 123 4.4E-21 T 06-07-2017 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 GTHT12_RS06130 1a21b50c1946c145879618d3b653ddc7 215 Gene3D G3DSA:2.60.120.320 124 208 1.5E-12 T 06-07-2017 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 GTHT12_RS06130 1a21b50c1946c145879618d3b653ddc7 215 SMART SM00983 139 205 1.5E-23 T 06-07-2017 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 GTHT12_RS06130 1a21b50c1946c145879618d3b653ddc7 215 SUPERFAMILY SSF63862 130 209 1.2E-16 T 06-07-2017 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 GTHT12_RS06130 1a21b50c1946c145879618d3b653ddc7 215 SUPERFAMILY SSF63999 3 126 6.15E-29 T 06-07-2017 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 GTHT12_RS06130 1a21b50c1946c145879618d3b653ddc7 215 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 150 204 6.1E-15 T 06-07-2017 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 GTHT12_RS03560 28b2c3c71d427f4f4b7710d27e217172 388 Pfam PF14398 YheC/D like ATP-grasp 149 373 6.6E-43 T 06-07-2017 IPR026838 Endospore coat-associated protein YheC/D GTHT12_RS03560 28b2c3c71d427f4f4b7710d27e217172 388 SUPERFAMILY SSF56059 178 360 2.08E-10 T 06-07-2017 GTHT12_RS03070 c6066affddbfad6221eb80713e05c6f0 225 Pfam PF00872 Transposase, Mutator family 3 202 6.0E-53 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS03070 c6066affddbfad6221eb80713e05c6f0 225 ProSitePatterns PS01007 Transposases, Mutator family, signature. 57 81 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS15695 8015d7f3f5cf452398fa778dd27a329e 489 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 14 466 4.2E-155 T 06-07-2017 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 GTHT12_RS15695 8015d7f3f5cf452398fa778dd27a329e 489 PIRSF PIRSF005690 8 481 4.6E-145 T 06-07-2017 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 GTHT12_RS01475 c04e80a115d09c6d6f520adaa936490c 244 Pfam PF02517 CAAX protease self-immunity 128 213 6.4E-18 T 06-07-2017 IPR003675 CAAX amino terminal protease GO:0016020 GTHT12_RS10470 41d93cf66222811af0a7a0714834ad10 411 TIGRFAM TIGR00299 TIGR00299: TIGR00299 family protein 3 393 2.4E-111 T 06-07-2017 IPR002822 Uncharacterised protein family UPF0272 GTHT12_RS10470 41d93cf66222811af0a7a0714834ad10 411 Gene3D G3DSA:3.30.70.1380 258 347 2.9E-33 T 06-07-2017 GTHT12_RS10470 41d93cf66222811af0a7a0714834ad10 411 Pfam PF01969 Protein of unknown function DUF111 4 397 6.0E-147 T 06-07-2017 IPR002822 Uncharacterised protein family UPF0272 GTHT12_RS10470 41d93cf66222811af0a7a0714834ad10 411 Hamap MF_01074 UPF0272 protein . 1 407 41.536 T 06-07-2017 IPR002822 Uncharacterised protein family UPF0272 GTHT12_RS10470 41d93cf66222811af0a7a0714834ad10 411 Gene3D G3DSA:3.10.20.300 348 409 3.5E-13 T 06-07-2017 GTHT12_RS16280 6f53e18474edde683aa12c5e9f25dea1 458 Pfam PF00271 Helicase conserved C-terminal domain 318 417 1.8E-12 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS16280 6f53e18474edde683aa12c5e9f25dea1 458 SMART SM00490 337 418 1.0E-10 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS16280 6f53e18474edde683aa12c5e9f25dea1 458 Pfam PF04851 Type III restriction enzyme, res subunit 115 263 7.7E-9 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 GTHT12_RS16280 6f53e18474edde683aa12c5e9f25dea1 458 Gene3D G3DSA:3.40.50.300 311 440 2.5E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16280 6f53e18474edde683aa12c5e9f25dea1 458 SUPERFAMILY SSF52540 127 429 1.67E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16280 6f53e18474edde683aa12c5e9f25dea1 458 Gene3D G3DSA:3.40.50.300 111 283 2.7E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16280 6f53e18474edde683aa12c5e9f25dea1 458 SMART SM00487 111 293 1.7E-14 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain GTHT12_RS10145 a1c7723c2ee330bad3ded6a34d9cdd1b 282 Gene3D G3DSA:3.30.1360.130 209 272 1.2E-13 T 06-07-2017 GTHT12_RS10145 a1c7723c2ee330bad3ded6a34d9cdd1b 282 SUPERFAMILY SSF63992 1 272 2.75E-84 T 06-07-2017 IPR007035 Peptidase M55, D-aminopeptidase GTHT12_RS10145 a1c7723c2ee330bad3ded6a34d9cdd1b 282 PIRSF PIRSF015853 1 275 2.2E-85 T 06-07-2017 IPR007035 Peptidase M55, D-aminopeptidase GTHT12_RS10145 a1c7723c2ee330bad3ded6a34d9cdd1b 282 Gene3D G3DSA:3.40.50.10780 1 208 4.0E-73 T 06-07-2017 IPR027476 D-aminopeptidase, N-terminal GTHT12_RS10145 a1c7723c2ee330bad3ded6a34d9cdd1b 282 Pfam PF04951 D-aminopeptidase 1 262 1.0E-95 T 06-07-2017 IPR007035 Peptidase M55, D-aminopeptidase GTHT12_RS11620 dec159a584c036ee842734291354b47b 367 SUPERFAMILY SSF48179 175 284 2.61E-34 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GTHT12_RS11620 dec159a584c036ee842734291354b47b 367 Pfam PF01842 ACT domain 298 337 9.7E-8 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 GTHT12_RS11620 dec159a584c036ee842734291354b47b 367 Gene3D G3DSA:3.40.50.720 4 181 9.7E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS11620 dec159a584c036ee842734291354b47b 367 SUPERFAMILY SSF51735 5 171 1.46E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS11620 dec159a584c036ee842734291354b47b 367 Pfam PF02153 Prephenate dehydrogenase 17 267 9.4E-81 T 06-07-2017 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 GTHT12_RS11620 dec159a584c036ee842734291354b47b 367 Gene3D G3DSA:3.30.70.260 298 356 1.8E-5 T 06-07-2017 GTHT12_RS11620 dec159a584c036ee842734291354b47b 367 SUPERFAMILY SSF55021 290 360 1.07E-9 T 06-07-2017 GTHT12_RS06200 0f811aeaa228e7dd9e2da402331aa547 1187 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1171 3.5E-77 T 06-07-2017 IPR003395 RecF/RecN/SMC, N-terminal GTHT12_RS06200 0f811aeaa228e7dd9e2da402331aa547 1187 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1178 0.0 T 06-07-2017 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 GTHT12_RS06200 0f811aeaa228e7dd9e2da402331aa547 1187 PIRSF PIRSF005719 1 1186 0.0 T 06-07-2017 IPR024704 Structural maintenance of chromosomes protein GTHT12_RS06200 0f811aeaa228e7dd9e2da402331aa547 1187 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1180 25.546 T 06-07-2017 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 GTHT12_RS06200 0f811aeaa228e7dd9e2da402331aa547 1187 Gene3D G3DSA:3.40.50.300 1027 1180 4.7E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06200 0f811aeaa228e7dd9e2da402331aa547 1187 Gene3D G3DSA:3.40.50.300 1 163 4.7E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06200 0f811aeaa228e7dd9e2da402331aa547 1187 SUPERFAMILY SSF75553 484 686 2.22E-55 T 06-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 GTHT12_RS06200 0f811aeaa228e7dd9e2da402331aa547 1187 SMART SM00968 518 637 1.6E-42 T 06-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 GTHT12_RS06200 0f811aeaa228e7dd9e2da402331aa547 1187 Pfam PF06470 SMC proteins Flexible Hinge Domain 518 637 3.5E-29 T 06-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 GTHT12_RS06200 0f811aeaa228e7dd9e2da402331aa547 1187 SUPERFAMILY SSF52540 979 1178 1.74E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06200 0f811aeaa228e7dd9e2da402331aa547 1187 SUPERFAMILY SSF52540 1 207 1.74E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05190 531724b1a20558819039cb74fcc97ebd 378 Pfam PF00589 Phage integrase family 172 352 6.0E-34 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS05190 531724b1a20558819039cb74fcc97ebd 378 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 29 120 6.6E-10 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 GTHT12_RS05190 531724b1a20558819039cb74fcc97ebd 378 SUPERFAMILY SSF56349 163 359 8.54E-47 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 GTHT12_RS05190 531724b1a20558819039cb74fcc97ebd 378 SUPERFAMILY SSF56349 29 133 8.54E-47 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 GTHT12_RS05190 531724b1a20558819039cb74fcc97ebd 378 Gene3D G3DSA:1.10.150.130 29 130 1.3E-15 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal GTHT12_RS05190 531724b1a20558819039cb74fcc97ebd 378 Gene3D G3DSA:1.10.443.10 172 357 1.1E-42 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS15555 573b96a306ec3d6a80d0feeebc8b546f 100 Gene3D G3DSA:3.30.1980.10 1 99 9.1E-42 T 06-07-2017 IPR014931 Protein of unknown function DUF1805 GTHT12_RS15555 573b96a306ec3d6a80d0feeebc8b546f 100 Pfam PF08827 Domain of unknown function (DUF1805) 37 99 7.6E-26 T 06-07-2017 IPR014931 Protein of unknown function DUF1805 GTHT12_RS15555 573b96a306ec3d6a80d0feeebc8b546f 100 SUPERFAMILY SSF102891 1 99 2.09E-36 T 06-07-2017 IPR014931 Protein of unknown function DUF1805 GTHT12_RS14730 6f6c2d0eb3498925a85aefcdb098dcd3 59 Pfam PF10957 Protein of unknown function (DUF2758) 1 59 3.4E-35 T 06-07-2017 IPR020296 Sporulation protein Cse60 GTHT12_RS14730 6f6c2d0eb3498925a85aefcdb098dcd3 59 ProDom PD052690 CSE60 CYTOSOLIC YTEV LJ928 SPORULATION ORF85 PROPHAGE 1 59 5.0E-28 T 06-07-2017 IPR020296 Sporulation protein Cse60 GTHT12_RS07440 731c6f41e56f690b20a213dac72234ca 290 PIRSF PIRSF006221 3 290 4.3E-83 T 06-07-2017 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 GTHT12_RS07440 731c6f41e56f690b20a213dac72234ca 290 Pfam PF03881 Fructosamine kinase 6 287 1.9E-80 T 06-07-2017 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 GTHT12_RS07440 731c6f41e56f690b20a213dac72234ca 290 SUPERFAMILY SSF56112 5 286 5.56E-50 T 06-07-2017 IPR011009 Protein kinase-like domain GTHT12_RS07440 731c6f41e56f690b20a213dac72234ca 290 Gene3D G3DSA:3.90.1200.10 98 268 5.5E-12 T 06-07-2017 GTHT12_RS07440 731c6f41e56f690b20a213dac72234ca 290 Gene3D G3DSA:3.30.200.20 23 92 7.0E-4 T 06-07-2017 GTHT12_RS11795 4a557c2b3e2d4136d28e00a092372570 224 TIGRFAM TIGR00017 cmk: cytidylate kinase 5 217 4.3E-84 T 06-07-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 GTHT12_RS11795 4a557c2b3e2d4136d28e00a092372570 224 Gene3D G3DSA:3.40.50.300 4 220 1.5E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11795 4a557c2b3e2d4136d28e00a092372570 224 SUPERFAMILY SSF52540 6 222 3.78E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11795 4a557c2b3e2d4136d28e00a092372570 224 Hamap MF_00238 Cytidylate kinase [cmk]. 5 223 34.31 T 06-07-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 GTHT12_RS11795 4a557c2b3e2d4136d28e00a092372570 224 Pfam PF02224 Cytidylate kinase 7 220 2.3E-79 T 06-07-2017 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 GTHT12_RS06560 3c494bcbb55d53d493ff062673d1d41b 128 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 3 111 2.4E-40 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 GTHT12_RS06560 3c494bcbb55d53d493ff062673d1d41b 128 SUPERFAMILY SSF89919 2 110 4.71E-38 T 06-07-2017 IPR023799 Ribosome-binding factor A domain GTHT12_RS06560 3c494bcbb55d53d493ff062673d1d41b 128 ProSitePatterns PS01319 Ribosome-binding factor A signature. 73 94 - T 06-07-2017 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 GTHT12_RS06560 3c494bcbb55d53d493ff062673d1d41b 128 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 7 91 1.0E-39 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 GTHT12_RS06560 3c494bcbb55d53d493ff062673d1d41b 128 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 1 114 23.39 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 GTHT12_RS06560 3c494bcbb55d53d493ff062673d1d41b 128 Gene3D G3DSA:3.30.300.20 2 114 2.2E-45 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta GTHT12_RS06560 3c494bcbb55d53d493ff062673d1d41b 128 Pfam PF02033 Ribosome-binding factor A 4 107 1.3E-34 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 GTHT12_RS02390 cf656f872813276969d59c2a7676fe82 454 Gene3D G3DSA:1.10.1060.10 12 110 1.5E-20 T 06-07-2017 GTHT12_RS02390 cf656f872813276969d59c2a7676fe82 454 Pfam PF13183 4Fe-4S dicluster domain 23 92 4.3E-12 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain GTHT12_RS02390 cf656f872813276969d59c2a7676fe82 454 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 26 37 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GTHT12_RS02390 cf656f872813276969d59c2a7676fe82 454 Pfam PF02754 Cysteine-rich domain 328 413 4.3E-16 T 06-07-2017 IPR004017 Cysteine-rich domain GTHT12_RS02390 cf656f872813276969d59c2a7676fe82 454 Pfam PF02754 Cysteine-rich domain 198 279 1.9E-19 T 06-07-2017 IPR004017 Cysteine-rich domain GTHT12_RS02390 cf656f872813276969d59c2a7676fe82 454 SUPERFAMILY SSF46548 14 108 4.53E-20 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 GTHT12_RS02390 cf656f872813276969d59c2a7676fe82 454 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 78 89 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GTHT12_RS02390 cf656f872813276969d59c2a7676fe82 454 PIRSF PIRSF000139 6 445 2.7E-145 T 06-07-2017 IPR012257 Glycolate oxidase, iron-sulphur subunit GTHT12_RS02920 1d053509515ae4bf62c4ef8cfb8eabca 53 Pfam PF14139 YpzG-like protein 1 53 2.2E-23 T 06-07-2017 IPR025413 YpzG-like protein GTHT12_RS10675 adaf7422761c3b16cc9f20caa7a93893 376 SUPERFAMILY SSF56300 69 331 1.75E-41 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like GTHT12_RS10675 adaf7422761c3b16cc9f20caa7a93893 376 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 69 295 2.8E-58 T 06-07-2017 IPR019079 Capsule synthesis protein, CapA GTHT12_RS10675 adaf7422761c3b16cc9f20caa7a93893 376 Gene3D G3DSA:3.60.21.30 87 291 2.5E-20 T 06-07-2017 GTHT12_RS10675 adaf7422761c3b16cc9f20caa7a93893 376 SMART SM00854 69 296 1.5E-89 T 06-07-2017 IPR019079 Capsule synthesis protein, CapA GTHT12_RS15330 28f2aaed869cb63213f235e7a3868200 207 Pfam PF00929 Exonuclease 9 174 1.3E-21 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III GTHT12_RS15330 28f2aaed869cb63213f235e7a3868200 207 SUPERFAMILY SSF53098 6 180 4.03E-29 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS15330 28f2aaed869cb63213f235e7a3868200 207 Gene3D G3DSA:3.30.420.10 5 187 9.1E-42 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS15330 28f2aaed869cb63213f235e7a3868200 207 SMART SM00479 6 183 2.4E-28 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III GTHT12_RS16090 5c7b9554ffd05ddb77490267254b2e0c 297 PIRSF PIRSF003097 1 297 1.0E-84 T 06-07-2017 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 GTHT12_RS16090 5c7b9554ffd05ddb77490267254b2e0c 297 Pfam PF02687 FtsX-like permease family 175 295 9.9E-12 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 GTHT12_RS15490 020328b29dc0883601fbf5ad5b28f4f1 145 Pfam PF01934 Protein of unknown function DUF86 11 128 2.5E-23 T 06-07-2017 IPR008201 Protein of unknown function DUF86 GTHT12_RS15490 020328b29dc0883601fbf5ad5b28f4f1 145 Gene3D G3DSA:1.20.120.580 1 143 5.3E-52 T 06-07-2017 GTHT12_RS08405 0b0bc5db2311d66a69736bc31429c83f 187 SUPERFAMILY SSF52833 6 186 5.43E-55 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS08405 0b0bc5db2311d66a69736bc31429c83f 187 Pfam PF00578 AhpC/TSA family 12 135 1.5E-19 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GTHT12_RS08405 0b0bc5db2311d66a69736bc31429c83f 187 Gene3D G3DSA:3.40.30.10 11 177 2.6E-33 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS16225 a3abdaf50b48306245a97f4f6ae689f7 301 SUPERFAMILY SSF64518 2 301 1.96E-69 T 06-07-2017 GTHT12_RS16225 a3abdaf50b48306245a97f4f6ae689f7 301 Pfam PF00700 Bacterial flagellin C-terminal helical region 218 300 3.1E-9 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 GTHT12_RS16225 a3abdaf50b48306245a97f4f6ae689f7 301 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 140 3.7E-27 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 GTHT12_RS16225 a3abdaf50b48306245a97f4f6ae689f7 301 Gene3D G3DSA:1.20.1330.10 52 253 6.0E-39 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 GTHT12_RS16225 a3abdaf50b48306245a97f4f6ae689f7 301 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 181 9.0E-60 T 06-07-2017 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 GTHT12_RS09480 931423c53f4510c9116f3ee034c9dd25 247 TIGRFAM TIGR00123 cbiM: cobalamin biosynthesis protein CbiM 29 236 7.9E-90 T 06-07-2017 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 GTHT12_RS09480 931423c53f4510c9116f3ee034c9dd25 247 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 30 235 4.9E-53 T 06-07-2017 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 GTHT12_RS09480 931423c53f4510c9116f3ee034c9dd25 247 Hamap MF_01462 Cobalt transport protein CbiM [cbiM]. 29 244 28.828 T 06-07-2017 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 GTHT12_RS14465 9eda933285c8e27c27e2ca861e2e19e9 160 Pfam PF11799 impB/mucB/samB family C-terminal domain 1 104 2.3E-15 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 GTHT12_RS14465 9eda933285c8e27c27e2ca861e2e19e9 160 Gene3D G3DSA:3.30.1490.100 1 107 1.4E-18 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 GTHT12_RS14465 9eda933285c8e27c27e2ca861e2e19e9 160 SUPERFAMILY SSF100879 1 98 3.34E-19 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 GTHT12_RS09025 1e77396742fac0320984b7e12b843b14 33 Pfam PF06953 Arsenical resistance operon trans-acting repressor ArsD 2 31 3.7E-9 T 06-07-2017 IPR010712 Arsenical-resistance operon trans-acting repressor ArsD GO:0003677|GO:0045892|GO:0046685 GTHT12_RS08085 b584ee276ffde19f9c1458b5b2092893 479 Gene3D G3DSA:3.50.50.60 139 278 1.4E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS08085 b584ee276ffde19f9c1458b5b2092893 479 Gene3D G3DSA:3.50.50.60 77 104 1.4E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS08085 b584ee276ffde19f9c1458b5b2092893 479 Gene3D G3DSA:3.50.50.60 4 39 1.4E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS08085 b584ee276ffde19f9c1458b5b2092893 479 Gene3D G3DSA:3.50.50.60 410 474 3.8E-5 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS08085 b584ee276ffde19f9c1458b5b2092893 479 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 221 8.3E-7 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS08085 b584ee276ffde19f9c1458b5b2092893 479 SUPERFAMILY SSF51905 426 476 2.51E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS08085 b584ee276ffde19f9c1458b5b2092893 479 SUPERFAMILY SSF51905 158 245 2.51E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS08085 b584ee276ffde19f9c1458b5b2092893 479 SUPERFAMILY SSF51905 3 115 2.51E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS16730 f397f8d5e5fd559c797925c5f29746a7 435 Gene3D G3DSA:1.10.10.10 353 432 2.4E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS16730 f397f8d5e5fd559c797925c5f29746a7 435 SUPERFAMILY SSF46785 382 432 9.72E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS01125 ae655109b52c8373ed4984c466e34c31 135 Pfam PF07681 DoxX 8 88 4.1E-16 T 06-07-2017 IPR032808 DoxX family GTHT12_RS15420 5aafafb04f1a0c1d77985ec3ad0dd870 330 Gene3D G3DSA:3.50.50.60 128 248 2.4E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS15420 5aafafb04f1a0c1d77985ec3ad0dd870 330 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 297 1.4E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS15420 5aafafb04f1a0c1d77985ec3ad0dd870 330 SUPERFAMILY SSF51905 8 307 5.64E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS15420 5aafafb04f1a0c1d77985ec3ad0dd870 330 Hamap MF_01685 Ferredoxin--NADP reductase. 7 329 45.144 T 06-07-2017 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101|MetaCyc: PWY-7230 GTHT12_RS15420 5aafafb04f1a0c1d77985ec3ad0dd870 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 66 76 8.7E-26 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS15420 5aafafb04f1a0c1d77985ec3ad0dd870 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 113 121 8.7E-26 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS15420 5aafafb04f1a0c1d77985ec3ad0dd870 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 203 219 8.7E-26 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS15420 5aafafb04f1a0c1d77985ec3ad0dd870 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 8.7E-26 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS15420 5aafafb04f1a0c1d77985ec3ad0dd870 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 152 176 8.7E-26 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS15420 5aafafb04f1a0c1d77985ec3ad0dd870 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 8.7E-26 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS15420 5aafafb04f1a0c1d77985ec3ad0dd870 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 3.3E-18 T 06-07-2017 GTHT12_RS15420 5aafafb04f1a0c1d77985ec3ad0dd870 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 3.3E-18 T 06-07-2017 GTHT12_RS15420 5aafafb04f1a0c1d77985ec3ad0dd870 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 3.3E-18 T 06-07-2017 GTHT12_RS15420 5aafafb04f1a0c1d77985ec3ad0dd870 330 Gene3D G3DSA:3.50.50.60 249 322 1.0E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS15420 5aafafb04f1a0c1d77985ec3ad0dd870 330 Gene3D G3DSA:3.50.50.60 7 127 1.0E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS00580 f06f430f4e5e65c18e982177599bbe1e 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 49 1.5E-16 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00580 f06f430f4e5e65c18e982177599bbe1e 49 Pfam PF00471 Ribosomal protein L33 4 49 1.6E-19 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00580 f06f430f4e5e65c18e982177599bbe1e 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 17.272 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00580 f06f430f4e5e65c18e982177599bbe1e 49 SUPERFAMILY SSF57829 1 49 1.53E-16 T 06-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 GTHT12_RS05945 baee676248080889497607935c440161 224 Gene3D G3DSA:3.20.20.10 1 223 4.1E-79 T 06-07-2017 IPR029066 PLP-binding barrel GTHT12_RS05945 baee676248080889497607935c440161 224 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 2 222 7.3E-50 T 06-07-2017 IPR011078 Uncharacterised protein family UPF0001 GTHT12_RS05945 baee676248080889497607935c440161 224 SUPERFAMILY SSF51419 1 222 5.63E-74 T 06-07-2017 IPR029066 PLP-binding barrel GTHT12_RS05945 baee676248080889497607935c440161 224 Pfam PF01168 Alanine racemase, N-terminal domain 6 222 2.7E-21 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GTHT12_RS05945 baee676248080889497607935c440161 224 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 74 88 - T 06-07-2017 IPR011078 Uncharacterised protein family UPF0001 GTHT12_RS05945 baee676248080889497607935c440161 224 PIRSF PIRSF004848 1 224 6.3E-66 T 06-07-2017 IPR011078 Uncharacterised protein family UPF0001 GTHT12_RS02355 576d744417e904e40ae0180ef76de6e3 310 SUPERFAMILY SSF51735 97 275 2.18E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS02355 576d744417e904e40ae0180ef76de6e3 310 Gene3D G3DSA:3.40.50.720 95 275 2.3E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS02355 576d744417e904e40ae0180ef76de6e3 310 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 115 275 2.9E-44 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 GTHT12_RS16000 9f606b042925573204000d4eb556d7f9 207 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 181 5.7E-62 T 06-07-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 GTHT12_RS16000 9f606b042925573204000d4eb556d7f9 207 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 140 161 - T 06-07-2017 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 GTHT12_RS16000 9f606b042925573204000d4eb556d7f9 207 SUPERFAMILY SSF53850 1 204 1.74E-65 T 06-07-2017 GTHT12_RS16000 9f606b042925573204000d4eb556d7f9 207 Gene3D G3DSA:3.40.190.10 116 173 6.8E-29 T 06-07-2017 GTHT12_RS16000 9f606b042925573204000d4eb556d7f9 207 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 1 205 55.894 T 06-07-2017 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 GTHT12_RS16000 9f606b042925573204000d4eb556d7f9 207 Pfam PF01634 ATP phosphoribosyltransferase 51 201 1.4E-49 T 06-07-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 GTHT12_RS16000 9f606b042925573204000d4eb556d7f9 207 Gene3D G3DSA:3.40.190.10 1 115 2.0E-35 T 06-07-2017 GTHT12_RS05165 b20c3b868904b5192f511bfa65c2ee29 145 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 17 139 3.4E-28 T 06-07-2017 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 GTHT12_RS05165 b20c3b868904b5192f511bfa65c2ee29 145 PIRSF PIRSF006113 13 141 2.5E-18 T 06-07-2017 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 GTHT12_RS05165 b20c3b868904b5192f511bfa65c2ee29 145 Gene3D G3DSA:3.30.479.10 13 141 7.3E-40 T 06-07-2017 GTHT12_RS05165 b20c3b868904b5192f511bfa65c2ee29 145 SUPERFAMILY SSF55620 11 139 1.89E-33 T 06-07-2017 GTHT12_RS05165 b20c3b868904b5192f511bfa65c2ee29 145 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 16 111 8.8E-29 T 06-07-2017 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 GTHT12_RS09535 6a69ac19efeb2b76cbadd638c0197814 249 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 54 237 2.7E-63 T 06-07-2017 IPR028055 Membrane insertase YidC/Oxa1, C-terminal GTHT12_RS09535 6a69ac19efeb2b76cbadd638c0197814 249 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 1 241 31.013 T 06-07-2017 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes GTHT12_RS09535 6a69ac19efeb2b76cbadd638c0197814 249 Pfam PF02096 60Kd inner membrane protein 55 237 1.9E-57 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 GTHT12_RS09535 6a69ac19efeb2b76cbadd638c0197814 249 PRINTS PR00701 60kDa inner membrane protein signature 120 143 8.1E-18 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 GTHT12_RS09535 6a69ac19efeb2b76cbadd638c0197814 249 PRINTS PR00701 60kDa inner membrane protein signature 165 187 8.1E-18 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 GTHT12_RS10225 44ba786972375170e2c593b753cad8ce 497 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 108 496 1.5E-162 T 06-07-2017 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 GTHT12_RS10225 44ba786972375170e2c593b753cad8ce 497 SMART SM00858 11 82 1.8E-13 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 GTHT12_RS10225 44ba786972375170e2c593b753cad8ce 497 Pfam PF08666 SAF domain 11 80 3.5E-13 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 GTHT12_RS09870 c9f3d2d6176cac6bac1ffd0b21819985 684 Pfam PF03648 Glycosyl hydrolase family 67 N-terminus 8 126 1.1E-20 T 06-07-2017 IPR005154 Alpha glucuronidase, N-terminal GO:0045493|GO:0046559 GTHT12_RS09870 c9f3d2d6176cac6bac1ffd0b21819985 684 Gene3D G3DSA:3.90.1330.10 480 683 4.2E-93 T 06-07-2017 IPR011099 Glycosyl hydrolase family 67, C-terminal GO:0005576|GO:0045493|GO:0046559 GTHT12_RS09870 c9f3d2d6176cac6bac1ffd0b21819985 684 Pfam PF07488 Glycosyl hydrolase family 67 middle domain 130 457 3.2E-163 T 06-07-2017 IPR011100 Glycosyl hydrolase family 67, catalytic domain GO:0005576|GO:0045493|GO:0046559 GTHT12_RS09870 c9f3d2d6176cac6bac1ffd0b21819985 684 PIRSF PIRSF029900 2 684 0.0 T 06-07-2017 IPR011395 Alpha glucuronidase GO:0005576|GO:0045493|GO:0046559 GTHT12_RS09870 c9f3d2d6176cac6bac1ffd0b21819985 684 Pfam PF07477 Glycosyl hydrolase family 67 C-terminus 458 680 4.8E-102 T 06-07-2017 IPR011099 Glycosyl hydrolase family 67, C-terminal GO:0005576|GO:0045493|GO:0046559 GTHT12_RS09870 c9f3d2d6176cac6bac1ffd0b21819985 684 SUPERFAMILY SSF55545 5 146 9.77E-33 T 06-07-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 GTHT12_RS09870 c9f3d2d6176cac6bac1ffd0b21819985 684 SUPERFAMILY SSF51445 148 684 1.74E-253 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS09870 c9f3d2d6176cac6bac1ffd0b21819985 684 Gene3D G3DSA:3.20.20.80 153 478 3.7E-173 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS09870 c9f3d2d6176cac6bac1ffd0b21819985 684 Gene3D G3DSA:3.30.379.10 5 152 1.0E-35 T 06-07-2017 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 GTHT12_RS06210 98d4b023d522b9af18ba01bbe4bf704a 110 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 2 92 1.7E-39 T 06-07-2017 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like GTHT12_RS06210 98d4b023d522b9af18ba01bbe4bf704a 110 Hamap MF_00245 UPF0122 protein . 2 103 21.839 T 06-07-2017 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like GTHT12_RS06210 98d4b023d522b9af18ba01bbe4bf704a 110 Gene3D G3DSA:1.10.10.10 2 101 5.0E-41 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS06210 98d4b023d522b9af18ba01bbe4bf704a 110 SUPERFAMILY SSF88659 2 99 2.24E-34 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS14700 8faca735ee2928f4da5dd37526d62d4e 470 Gene3D G3DSA:3.30.70.360 209 286 1.3E-26 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS14700 8faca735ee2928f4da5dd37526d62d4e 470 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 84 93 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 GTHT12_RS14700 8faca735ee2928f4da5dd37526d62d4e 470 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 15 465 2.3E-175 T 06-07-2017 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 GTHT12_RS14700 8faca735ee2928f4da5dd37526d62d4e 470 Gene3D G3DSA:3.30.70.360 287 378 9.2E-32 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS14700 8faca735ee2928f4da5dd37526d62d4e 470 SUPERFAMILY SSF55031 188 381 2.3E-54 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS14700 8faca735ee2928f4da5dd37526d62d4e 470 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 118 156 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 GTHT12_RS14700 8faca735ee2928f4da5dd37526d62d4e 470 SUPERFAMILY SSF53187 5 188 2.65E-75 T 06-07-2017 GTHT12_RS14700 8faca735ee2928f4da5dd37526d62d4e 470 SUPERFAMILY SSF53187 387 469 2.65E-75 T 06-07-2017 GTHT12_RS14700 8faca735ee2928f4da5dd37526d62d4e 470 Pfam PF01546 Peptidase family M20/M25/M40 87 466 9.9E-35 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 GTHT12_RS14700 8faca735ee2928f4da5dd37526d62d4e 470 Gene3D G3DSA:3.40.630.10 386 470 2.8E-75 T 06-07-2017 GTHT12_RS14700 8faca735ee2928f4da5dd37526d62d4e 470 Gene3D G3DSA:3.40.630.10 7 188 2.8E-75 T 06-07-2017 GTHT12_RS08805 f63bcbc2448acb8503d4740cd1b57512 238 Pfam PF00563 EAL domain 10 234 3.0E-38 T 06-07-2017 IPR001633 EAL domain GTHT12_RS08805 f63bcbc2448acb8503d4740cd1b57512 238 Gene3D G3DSA:3.20.20.450 7 235 2.3E-39 T 06-07-2017 IPR001633 EAL domain GTHT12_RS08805 f63bcbc2448acb8503d4740cd1b57512 238 SMART SM00052 6 237 2.9E-10 T 06-07-2017 IPR001633 EAL domain GTHT12_RS08805 f63bcbc2448acb8503d4740cd1b57512 238 SUPERFAMILY SSF141868 6 235 1.27E-45 T 06-07-2017 IPR001633 EAL domain GTHT12_RS14880 8ce49d08ac4408545acb74a7583a193a 493 Pfam PF13193 AMP-binding enzyme C-terminal domain 398 473 7.7E-23 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain GTHT12_RS14880 8ce49d08ac4408545acb74a7583a193a 493 Gene3D G3DSA:2.30.38.10 309 379 1.4E-25 T 06-07-2017 GTHT12_RS14880 8ce49d08ac4408545acb74a7583a193a 493 SUPERFAMILY SSF56801 3 483 1.27E-140 T 06-07-2017 GTHT12_RS14880 8ce49d08ac4408545acb74a7583a193a 493 Gene3D G3DSA:3.40.50.980 152 308 1.7E-33 T 06-07-2017 GTHT12_RS14880 8ce49d08ac4408545acb74a7583a193a 493 Hamap MF_00731 2-succinylbenzoate--CoA ligase [menE]. 4 482 49.617 T 06-07-2017 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 GTHT12_RS14880 8ce49d08ac4408545acb74a7583a193a 493 Gene3D G3DSA:3.30.300.30 385 481 2.9E-35 T 06-07-2017 GTHT12_RS14880 8ce49d08ac4408545acb74a7583a193a 493 ProSitePatterns PS00455 Putative AMP-binding domain signature. 147 158 - T 06-07-2017 IPR020845 AMP-binding, conserved site GTHT12_RS14880 8ce49d08ac4408545acb74a7583a193a 493 Gene3D G3DSA:3.40.50.980 3 151 2.5E-33 T 06-07-2017 GTHT12_RS14880 8ce49d08ac4408545acb74a7583a193a 493 TIGRFAM TIGR01923 menE: O-succinylbenzoate-CoA ligase 29 479 4.6E-143 T 06-07-2017 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 GTHT12_RS14880 8ce49d08ac4408545acb74a7583a193a 493 Pfam PF00501 AMP-binding enzyme 10 389 2.7E-82 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GTHT12_RS01745 7a2845e7216aaac8a3338fb6953935ef 265 SUPERFAMILY SSF158745 14 263 1.57E-58 T 06-07-2017 GTHT12_RS01745 7a2845e7216aaac8a3338fb6953935ef 265 PRINTS PR01953 Subtilin biosynthesis protein SpaC signature 34 50 1.0E-49 T 06-07-2017 IPR020452 Subtilin biosynthesis protein SpaC GTHT12_RS01745 7a2845e7216aaac8a3338fb6953935ef 265 PRINTS PR01953 Subtilin biosynthesis protein SpaC signature 86 110 1.0E-49 T 06-07-2017 IPR020452 Subtilin biosynthesis protein SpaC GTHT12_RS01745 7a2845e7216aaac8a3338fb6953935ef 265 PRINTS PR01953 Subtilin biosynthesis protein SpaC signature 140 168 1.0E-49 T 06-07-2017 IPR020452 Subtilin biosynthesis protein SpaC GTHT12_RS01745 7a2845e7216aaac8a3338fb6953935ef 265 PRINTS PR01953 Subtilin biosynthesis protein SpaC signature 7 31 1.0E-49 T 06-07-2017 IPR020452 Subtilin biosynthesis protein SpaC GTHT12_RS01745 7a2845e7216aaac8a3338fb6953935ef 265 PRINTS PR01953 Subtilin biosynthesis protein SpaC signature 207 225 1.0E-49 T 06-07-2017 IPR020452 Subtilin biosynthesis protein SpaC GTHT12_RS01745 7a2845e7216aaac8a3338fb6953935ef 265 Pfam PF05147 Lanthionine synthetase C-like protein 30 261 6.6E-56 T 06-07-2017 IPR007822 Lanthionine synthetase C-like GTHT12_RS01745 7a2845e7216aaac8a3338fb6953935ef 265 PRINTS PR01950 LanC-like protein superfamily signature 121 141 1.1E-15 T 06-07-2017 IPR007822 Lanthionine synthetase C-like GTHT12_RS01745 7a2845e7216aaac8a3338fb6953935ef 265 PRINTS PR01950 LanC-like protein superfamily signature 231 248 1.1E-15 T 06-07-2017 IPR007822 Lanthionine synthetase C-like GTHT12_RS01745 7a2845e7216aaac8a3338fb6953935ef 265 PRINTS PR01950 LanC-like protein superfamily signature 168 181 1.1E-15 T 06-07-2017 IPR007822 Lanthionine synthetase C-like GTHT12_RS01745 7a2845e7216aaac8a3338fb6953935ef 265 PRINTS PR01950 LanC-like protein superfamily signature 50 66 1.1E-15 T 06-07-2017 IPR007822 Lanthionine synthetase C-like GTHT12_RS01745 7a2845e7216aaac8a3338fb6953935ef 265 SMART SM01260 3 261 4.9E-12 T 06-07-2017 IPR007822 Lanthionine synthetase C-like GTHT12_RS16190 33f3503cbf916c8e65ecac00e561a2c4 281 Gene3D G3DSA:3.10.28.10 92 210 1.0E-11 T 06-07-2017 IPR027434 Homing endonuclease GO:0004519 GTHT12_RS16190 33f3503cbf916c8e65ecac00e561a2c4 281 Pfam PF03161 LAGLIDADG DNA endonuclease family 13 177 4.1E-16 T 06-07-2017 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 GTHT12_RS16190 33f3503cbf916c8e65ecac00e561a2c4 281 SUPERFAMILY SSF55608 3 205 1.87E-28 T 06-07-2017 IPR027434 Homing endonuclease GO:0004519 GTHT12_RS03820 b305698be9686e5dce0e31c4fc4eab1e 198 Pfam PF10737 Spore germination protein GerPC 21 194 2.0E-63 T 06-07-2017 IPR019673 Spore germination protein GerPC GTHT12_RS12555 7aca3053575ec027d246ad4c7e593b93 172 SUPERFAMILY SSF51230 93 169 1.44E-24 T 06-07-2017 IPR011053 Single hybrid motif GTHT12_RS12555 7aca3053575ec027d246ad4c7e593b93 172 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 126 143 - T 06-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 GTHT12_RS12555 7aca3053575ec027d246ad4c7e593b93 172 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 170 1.2E-52 T 06-07-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 GTHT12_RS12555 7aca3053575ec027d246ad4c7e593b93 172 Pfam PF00364 Biotin-requiring enzyme 95 167 6.5E-24 T 06-07-2017 IPR000089 Biotin/lipoyl attachment GTHT12_RS12555 7aca3053575ec027d246ad4c7e593b93 172 Gene3D G3DSA:2.40.50.100 93 169 6.9E-31 T 06-07-2017 GTHT12_RS12555 7aca3053575ec027d246ad4c7e593b93 172 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 99 112 4.6E-17 T 06-07-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 GTHT12_RS12555 7aca3053575ec027d246ad4c7e593b93 172 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 131 144 4.6E-17 T 06-07-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 GTHT12_RS12555 7aca3053575ec027d246ad4c7e593b93 172 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 116 130 4.6E-17 T 06-07-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 GTHT12_RS14675 48207351237f54a24820ec507c869eb3 260 Pfam PF01636 Phosphotransferase enzyme family 15 222 2.3E-25 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase GTHT12_RS14675 48207351237f54a24820ec507c869eb3 260 SUPERFAMILY SSF56112 2 228 6.37E-34 T 06-07-2017 IPR011009 Protein kinase-like domain GTHT12_RS14675 48207351237f54a24820ec507c869eb3 260 Gene3D G3DSA:3.90.1200.10 42 212 5.1E-20 T 06-07-2017 GTHT12_RS01230 4b0a5aa0a9e0fe60c8d10dcd17b09091 442 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 183 193 - T 06-07-2017 IPR022398 Peptidase S8, subtilisin, His-active site GTHT12_RS01230 4b0a5aa0a9e0fe60c8d10dcd17b09091 442 SUPERFAMILY SSF52743 65 439 1.18E-81 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 GTHT12_RS01230 4b0a5aa0a9e0fe60c8d10dcd17b09091 442 PRINTS PR00723 Subtilisin serine protease family (S8) signature 179 192 1.1E-18 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related GTHT12_RS01230 4b0a5aa0a9e0fe60c8d10dcd17b09091 442 PRINTS PR00723 Subtilisin serine protease family (S8) signature 142 161 1.1E-18 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related GTHT12_RS01230 4b0a5aa0a9e0fe60c8d10dcd17b09091 442 PRINTS PR00723 Subtilisin serine protease family (S8) signature 378 394 1.1E-18 T 06-07-2017 IPR015500 Peptidase S8, subtilisin-related GTHT12_RS01230 4b0a5aa0a9e0fe60c8d10dcd17b09091 442 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 147 157 - T 06-07-2017 IPR023827 Peptidase S8, subtilisin, Asp-active site GTHT12_RS01230 4b0a5aa0a9e0fe60c8d10dcd17b09091 442 Gene3D G3DSA:3.40.50.200 95 439 9.6E-88 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 GTHT12_RS01230 4b0a5aa0a9e0fe60c8d10dcd17b09091 442 Pfam PF00082 Subtilase family 142 428 1.1E-53 T 06-07-2017 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 GTHT12_RS01230 4b0a5aa0a9e0fe60c8d10dcd17b09091 442 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 379 389 - T 06-07-2017 IPR023828 Peptidase S8, subtilisin, Ser-active site GTHT12_RS02875 b385e2be95b4cea47aed764adfb2d611 670 Gene3D G3DSA:3.10.450.100 26 144 9.8E-35 T 06-07-2017 GTHT12_RS02875 b385e2be95b4cea47aed764adfb2d611 670 Pfam PF00905 Penicillin binding protein transpeptidase domain 355 666 9.2E-61 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 GTHT12_RS02875 b385e2be95b4cea47aed764adfb2d611 670 Gene3D G3DSA:3.30.1390.30 177 240 4.1E-20 T 06-07-2017 GTHT12_RS02875 b385e2be95b4cea47aed764adfb2d611 670 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 26 149 1.8E-29 T 06-07-2017 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 GTHT12_RS02875 b385e2be95b4cea47aed764adfb2d611 670 SUPERFAMILY SSF54427 29 145 4.25E-30 T 06-07-2017 IPR032710 NTF2-like domain GTHT12_RS02875 b385e2be95b4cea47aed764adfb2d611 670 SUPERFAMILY SSF56601 338 668 3.7E-81 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS02875 b385e2be95b4cea47aed764adfb2d611 670 Gene3D G3DSA:3.40.710.10 337 668 4.8E-80 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS02875 b385e2be95b4cea47aed764adfb2d611 670 Gene3D G3DSA:3.90.1310.10 241 334 2.8E-25 T 06-07-2017 GTHT12_RS02875 b385e2be95b4cea47aed764adfb2d611 670 SUPERFAMILY SSF56519 150 337 2.22E-38 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 GTHT12_RS02875 b385e2be95b4cea47aed764adfb2d611 670 Pfam PF03717 Penicillin-binding Protein dimerisation domain 156 320 4.5E-33 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 GTHT12_RS05460 2f7b4b4a3059ad3365438ee64218ea4b 330 Gene3D G3DSA:3.30.460.20 20 126 6.8E-32 T 06-07-2017 GTHT12_RS05460 2f7b4b4a3059ad3365438ee64218ea4b 330 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 19 316 3.4E-99 T 06-07-2017 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 GTHT12_RS05460 2f7b4b4a3059ad3365438ee64218ea4b 330 Pfam PF01544 CorA-like Mg2+ transporter protein 30 312 8.3E-82 T 06-07-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 GTHT12_RS05460 2f7b4b4a3059ad3365438ee64218ea4b 330 SUPERFAMILY SSF144083 251 313 2.35E-22 T 06-07-2017 GTHT12_RS05460 2f7b4b4a3059ad3365438ee64218ea4b 330 Gene3D G3DSA:1.20.58.340 127 238 4.1E-30 T 06-07-2017 GTHT12_RS05460 2f7b4b4a3059ad3365438ee64218ea4b 330 Gene3D G3DSA:1.20.58.340 240 316 3.4E-32 T 06-07-2017 GTHT12_RS05460 2f7b4b4a3059ad3365438ee64218ea4b 330 SUPERFAMILY SSF143865 22 250 2.09E-63 T 06-07-2017 GTHT12_RS06800 665149825f5a82b312843f8c9b4737fe 75 Gene3D G3DSA:2.30.30.100 1 74 4.4E-34 T 06-07-2017 GTHT12_RS06800 665149825f5a82b312843f8c9b4737fe 75 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 65 1.2E-33 T 06-07-2017 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 GTHT12_RS06800 665149825f5a82b312843f8c9b4737fe 75 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 65 30.829 T 06-07-2017 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 GTHT12_RS06800 665149825f5a82b312843f8c9b4737fe 75 SUPERFAMILY SSF50182 6 64 5.93E-25 T 06-07-2017 IPR010920 LSM domain GTHT12_RS13105 40428c85a3ced8c3fa59d16ee9f6e052 449 Gene3D G3DSA:3.80.30.20 141 371 1.0E-76 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe GTHT12_RS13105 40428c85a3ced8c3fa59d16ee9f6e052 449 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 429 4.8E-152 T 06-07-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 GTHT12_RS13105 40428c85a3ced8c3fa59d16ee9f6e052 449 Pfam PF04055 Radical SAM superfamily 149 319 7.5E-30 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 GTHT12_RS13105 40428c85a3ced8c3fa59d16ee9f6e052 449 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 421 4.4E-144 T 06-07-2017 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 GTHT12_RS13105 40428c85a3ced8c3fa59d16ee9f6e052 449 Pfam PF01938 TRAM domain 374 433 4.1E-7 T 06-07-2017 IPR002792 TRAM domain GTHT12_RS13105 40428c85a3ced8c3fa59d16ee9f6e052 449 Pfam PF00919 Uncharacterized protein family UPF0004 4 98 5.2E-26 T 06-07-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 GTHT12_RS13105 40428c85a3ced8c3fa59d16ee9f6e052 449 SUPERFAMILY SSF102114 119 364 2.62E-61 T 06-07-2017 GTHT12_RS13105 40428c85a3ced8c3fa59d16ee9f6e052 449 SMART SM00729 143 361 5.8E-63 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 GTHT12_RS13105 40428c85a3ced8c3fa59d16ee9f6e052 449 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 147 167 - T 06-07-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 GTHT12_RS15905 25c19bf699e1c44b8c1eef2bbbd2fcf1 339 Gene3D G3DSA:3.40.50.1360 96 337 1.7E-94 T 06-07-2017 GTHT12_RS15905 25c19bf699e1c44b8c1eef2bbbd2fcf1 339 SUPERFAMILY SSF100950 92 337 2.15E-70 T 06-07-2017 GTHT12_RS15905 25c19bf699e1c44b8c1eef2bbbd2fcf1 339 SUPERFAMILY SSF46785 19 83 1.45E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS15905 25c19bf699e1c44b8c1eef2bbbd2fcf1 339 Pfam PF04198 Putative sugar-binding domain 93 337 5.2E-76 T 06-07-2017 IPR007324 Sugar-binding domain, putative GO:0030246 GTHT12_RS15905 25c19bf699e1c44b8c1eef2bbbd2fcf1 339 Gene3D G3DSA:1.10.10.10 1 94 6.1E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS18290 b933847ed83d26078af1cd1d8e4ab77f 242 Pfam PF13814 Replication-relaxation 73 161 3.7E-6 T 06-07-2017 IPR025855 Plasmid replication-relaxation GTHT12_RS05640 c0ce17a537893c080f26c079524f6cf7 107 Pfam PF14036 YlaH-like protein 24 98 1.5E-32 T 06-07-2017 IPR025620 YlaH-like protein GTHT12_RS03595 93c7fce60d4ecfaea98780ef3cbdc024 501 TIGRFAM TIGR03994 rSAM_HemZ: coproporphyrinogen dehydrogenase HemZ 94 495 9.4E-152 T 06-07-2017 IPR023995 Coproporphyrinogen III oxidase GTHT12_RS03595 93c7fce60d4ecfaea98780ef3cbdc024 501 Pfam PF04055 Radical SAM superfamily 184 355 1.1E-15 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 GTHT12_RS03595 93c7fce60d4ecfaea98780ef3cbdc024 501 SUPERFAMILY SSF102114 172 487 1.7E-70 T 06-07-2017 GTHT12_RS03595 93c7fce60d4ecfaea98780ef3cbdc024 501 SMART SM00729 176 400 1.9E-47 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 GTHT12_RS03595 93c7fce60d4ecfaea98780ef3cbdc024 501 Gene3D G3DSA:3.80.30.20 177 410 1.3E-37 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe GTHT12_RS13975 92c40f731a9fd8ad4d87846791d857b3 171 Pfam PF03358 NADPH-dependent FMN reductase 4 141 9.5E-31 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 GTHT12_RS13975 92c40f731a9fd8ad4d87846791d857b3 171 Gene3D G3DSA:3.40.50.360 4 169 3.8E-30 T 06-07-2017 IPR029039 Flavoprotein-like domain GTHT12_RS13975 92c40f731a9fd8ad4d87846791d857b3 171 SUPERFAMILY SSF52218 4 168 3.74E-32 T 06-07-2017 IPR029039 Flavoprotein-like domain GTHT12_RS13975 92c40f731a9fd8ad4d87846791d857b3 171 TIGRFAM TIGR03567 FMN_reduc_SsuE: FMN reductase 4 170 1.8E-59 T 06-07-2017 IPR020048 NADPH-dependent FMN reductase, SsuE GO:0008752|GO:0046306|GO:0055114 KEGG: 00740+1.5.1.38|MetaCyc: PWY-7723 GTHT12_RS02450 7dee51e8b5c865b6e1ad9e8bb84f2dca 258 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 82 115 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 GTHT12_RS02450 7dee51e8b5c865b6e1ad9e8bb84f2dca 258 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 GTHT12_RS02450 7dee51e8b5c865b6e1ad9e8bb84f2dca 258 SUPERFAMILY SSF53790 1 246 1.96E-86 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS02450 7dee51e8b5c865b6e1ad9e8bb84f2dca 258 Gene3D G3DSA:3.30.950.10 118 247 9.9E-53 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS02450 7dee51e8b5c865b6e1ad9e8bb84f2dca 258 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 214 7.1E-52 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS02450 7dee51e8b5c865b6e1ad9e8bb84f2dca 258 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 2 238 6.8E-103 T 06-07-2017 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 GTHT12_RS02450 7dee51e8b5c865b6e1ad9e8bb84f2dca 258 Gene3D G3DSA:3.40.1010.10 1 117 3.6E-46 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS12120 a1efe81cef8f58f2b5ac53e080a0daa4 146 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 9 138 1.5E-44 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 GTHT12_RS12120 a1efe81cef8f58f2b5ac53e080a0daa4 146 SUPERFAMILY SSF50891 11 138 1.9E-49 T 06-07-2017 IPR029000 Cyclophilin-like domain GTHT12_RS12120 a1efe81cef8f58f2b5ac53e080a0daa4 146 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 100 112 1.2E-24 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 GTHT12_RS12120 a1efe81cef8f58f2b5ac53e080a0daa4 146 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 45 57 1.2E-24 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 GTHT12_RS12120 a1efe81cef8f58f2b5ac53e080a0daa4 146 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 113 128 1.2E-24 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 GTHT12_RS12120 a1efe81cef8f58f2b5ac53e080a0daa4 146 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 85 100 1.2E-24 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 GTHT12_RS12120 a1efe81cef8f58f2b5ac53e080a0daa4 146 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 19 34 1.2E-24 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 GTHT12_RS12120 a1efe81cef8f58f2b5ac53e080a0daa4 146 Gene3D G3DSA:2.40.100.10 7 138 2.1E-49 T 06-07-2017 IPR029000 Cyclophilin-like domain GTHT12_RS12120 a1efe81cef8f58f2b5ac53e080a0daa4 146 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 40 57 - T 06-07-2017 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 GTHT12_RS12120 a1efe81cef8f58f2b5ac53e080a0daa4 146 PIRSF PIRSF001467 3 146 2.3E-40 T 06-07-2017 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 GTHT12_RS08420 91ea2c9e4c08c5b5b761d090b4eb033b 248 Gene3D G3DSA:3.20.20.150 1 236 2.1E-64 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain GTHT12_RS08420 91ea2c9e4c08c5b5b761d090b4eb033b 248 SUPERFAMILY SSF51658 1 246 1.15E-54 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain GTHT12_RS07870 80fe97061d8776e40e1a2d50bda34e04 440 SUPERFAMILY SSF56176 8 207 1.21E-43 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 GTHT12_RS07870 80fe97061d8776e40e1a2d50bda34e04 440 Pfam PF01565 FAD binding domain 34 169 1.6E-30 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 GTHT12_RS07870 80fe97061d8776e40e1a2d50bda34e04 440 Gene3D G3DSA:3.30.43.10 33 89 1.2E-6 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 GTHT12_RS07870 80fe97061d8776e40e1a2d50bda34e04 440 SUPERFAMILY SSF55103 212 437 4.36E-19 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 GTHT12_RS07870 80fe97061d8776e40e1a2d50bda34e04 440 Gene3D G3DSA:3.30.465.10 90 207 4.4E-32 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 GTHT12_RS14175 cd03c0b8d2e51198f92820527cc80965 153 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 1.0E-70 T 06-07-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 GTHT12_RS14175 cd03c0b8d2e51198f92820527cc80965 153 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 89.113 T 06-07-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 GTHT12_RS14175 cd03c0b8d2e51198f92820527cc80965 153 Pfam PF03477 ATP cone domain 50 136 2.3E-21 T 06-07-2017 IPR005144 ATP-cone domain Reactome: R-HSA-499943 GTHT12_RS09395 b8b0bd61d6ec0c92d0ef0425e54bd42c 181 SUPERFAMILY SSF52540 5 181 7.84E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS09395 b8b0bd61d6ec0c92d0ef0425e54bd42c 181 PIRSF PIRSF015617 2 181 6.4E-61 T 06-07-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 GTHT12_RS09395 b8b0bd61d6ec0c92d0ef0425e54bd42c 181 Gene3D G3DSA:3.40.50.300 5 181 1.7E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS09395 b8b0bd61d6ec0c92d0ef0425e54bd42c 181 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 7 181 4.6E-53 T 06-07-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 GTHT12_RS09395 b8b0bd61d6ec0c92d0ef0425e54bd42c 181 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 7 181 2.7E-59 T 06-07-2017 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 GTHT12_RS16835 882d4528e361416cf15e72ce622eeab8 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 65 284 1.8E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS16835 882d4528e361416cf15e72ce622eeab8 292 Gene3D G3DSA:1.10.3720.10 4 279 4.9E-54 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS16835 882d4528e361416cf15e72ce622eeab8 292 SUPERFAMILY SSF161098 52 276 2.22E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS08950 0ea14f4237740939057ca9d853c1cb96 210 Pfam PF08818 Domain of unknown function (DU1801) 37 130 1.1E-14 T 06-07-2017 IPR014922 Domain of unknown function DUF1801 GTHT12_RS08950 0ea14f4237740939057ca9d853c1cb96 210 PIRSF PIRSF021308 15 210 5.4E-83 T 06-07-2017 IPR016786 Uncharacterised protein YdeI, bacterial GTHT12_RS08950 0ea14f4237740939057ca9d853c1cb96 210 SUPERFAMILY SSF159888 34 136 2.62E-17 T 06-07-2017 GTHT12_RS08950 0ea14f4237740939057ca9d853c1cb96 210 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 149 205 1.3E-19 T 06-07-2017 GTHT12_RS08725 9046597e4597e39371bb2737b9daf21a 208 Pfam PF01810 LysE type translocator 15 200 9.7E-27 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 GTHT12_RS13410 2a88e1b1df38757cc569f7ad19968f03 220 Pfam PF13424 Tetratricopeptide repeat 4 66 2.4E-8 T 06-07-2017 GTHT12_RS13410 2a88e1b1df38757cc569f7ad19968f03 220 Gene3D G3DSA:1.25.40.10 73 135 3.5E-16 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS13410 2a88e1b1df38757cc569f7ad19968f03 220 Gene3D G3DSA:1.25.40.10 4 72 1.6E-17 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS13410 2a88e1b1df38757cc569f7ad19968f03 220 Pfam PF13428 Tetratricopeptide repeat 70 110 2.4E-5 T 06-07-2017 GTHT12_RS13410 2a88e1b1df38757cc569f7ad19968f03 220 SMART SM00028 69 102 0.0015 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS13410 2a88e1b1df38757cc569f7ad19968f03 220 SMART SM00028 137 170 0.003 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS13410 2a88e1b1df38757cc569f7ad19968f03 220 SMART SM00028 103 136 0.057 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS13410 2a88e1b1df38757cc569f7ad19968f03 220 SMART SM00028 1 34 0.03 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS13410 2a88e1b1df38757cc569f7ad19968f03 220 SMART SM00028 171 204 3.1E-4 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS13410 2a88e1b1df38757cc569f7ad19968f03 220 SMART SM00028 35 68 0.0033 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 GTHT12_RS13410 2a88e1b1df38757cc569f7ad19968f03 220 Pfam PF13432 Tetratricopeptide repeat 154 204 2.5E-9 T 06-07-2017 GTHT12_RS13410 2a88e1b1df38757cc569f7ad19968f03 220 Gene3D G3DSA:1.25.40.10 136 207 1.4E-19 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS13410 2a88e1b1df38757cc569f7ad19968f03 220 SUPERFAMILY SSF48452 6 212 4.55E-38 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS13410 2a88e1b1df38757cc569f7ad19968f03 220 SMART SM00671 69 100 46.0 T 06-07-2017 IPR006597 Sel1-like repeat GTHT12_RS13410 2a88e1b1df38757cc569f7ad19968f03 220 SMART SM00671 171 202 5.7 T 06-07-2017 IPR006597 Sel1-like repeat GTHT12_RS13410 2a88e1b1df38757cc569f7ad19968f03 220 SMART SM00671 35 66 250.0 T 06-07-2017 IPR006597 Sel1-like repeat GTHT12_RS13410 2a88e1b1df38757cc569f7ad19968f03 220 SMART SM00671 137 168 230.0 T 06-07-2017 IPR006597 Sel1-like repeat GTHT12_RS16670 56c1d24da3cffd6aef1ed3937f571288 298 PRINTS PR00990 Ribokinase signature 205 216 4.7E-34 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 GTHT12_RS16670 56c1d24da3cffd6aef1ed3937f571288 298 PRINTS PR00990 Ribokinase signature 35 54 4.7E-34 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 GTHT12_RS16670 56c1d24da3cffd6aef1ed3937f571288 298 PRINTS PR00990 Ribokinase signature 106 119 4.7E-34 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 GTHT12_RS16670 56c1d24da3cffd6aef1ed3937f571288 298 PRINTS PR00990 Ribokinase signature 174 189 4.7E-34 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 GTHT12_RS16670 56c1d24da3cffd6aef1ed3937f571288 298 PRINTS PR00990 Ribokinase signature 8 29 4.7E-34 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 GTHT12_RS16670 56c1d24da3cffd6aef1ed3937f571288 298 SUPERFAMILY SSF53613 5 292 1.42E-82 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS16670 56c1d24da3cffd6aef1ed3937f571288 298 Pfam PF00294 pfkB family carbohydrate kinase 6 282 2.4E-70 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB GTHT12_RS16670 56c1d24da3cffd6aef1ed3937f571288 298 Hamap MF_01987 Ribokinase [rbsK]. 4 289 26.817 T 06-07-2017 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15 GTHT12_RS16670 56c1d24da3cffd6aef1ed3937f571288 298 Gene3D G3DSA:3.40.1190.20 5 293 2.5E-98 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS16670 56c1d24da3cffd6aef1ed3937f571288 298 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 6 287 1.1E-103 T 06-07-2017 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15 GTHT12_RS16670 56c1d24da3cffd6aef1ed3937f571288 298 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 234 247 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 GTHT12_RS04200 2dcf0c686a0c0b38cf5b2463b5b6d46d 344 SMART SM00859 2 140 9.9E-49 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 GTHT12_RS04200 2dcf0c686a0c0b38cf5b2463b5b6d46d 344 Gene3D G3DSA:3.30.360.10 157 312 3.8E-63 T 06-07-2017 GTHT12_RS04200 2dcf0c686a0c0b38cf5b2463b5b6d46d 344 Gene3D G3DSA:3.40.50.720 1 156 1.5E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS04200 2dcf0c686a0c0b38cf5b2463b5b6d46d 344 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 1 344 2.6E-140 T 06-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 GTHT12_RS04200 2dcf0c686a0c0b38cf5b2463b5b6d46d 344 SUPERFAMILY SSF55347 148 312 1.9E-56 T 06-07-2017 GTHT12_RS04200 2dcf0c686a0c0b38cf5b2463b5b6d46d 344 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 157 315 1.3E-28 T 06-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 GTHT12_RS04200 2dcf0c686a0c0b38cf5b2463b5b6d46d 344 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 338 44.009 T 06-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 GTHT12_RS04200 2dcf0c686a0c0b38cf5b2463b5b6d46d 344 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 143 159 - T 06-07-2017 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 GTHT12_RS04200 2dcf0c686a0c0b38cf5b2463b5b6d46d 344 SUPERFAMILY SSF51735 2 176 6.18E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS04200 2dcf0c686a0c0b38cf5b2463b5b6d46d 344 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 139 1.5E-34 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 GTHT12_RS06425 e0426923c187bd94fb6b5668efe5d19e 680 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 128 151 - T 06-07-2017 IPR025505 FHIPEP conserved site GTHT12_RS06425 e0426923c187bd94fb6b5668efe5d19e 680 PIRSF PIRSF005419 1 680 1.2E-265 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 GTHT12_RS06425 e0426923c187bd94fb6b5668efe5d19e 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 61 80 8.6E-56 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 GTHT12_RS06425 e0426923c187bd94fb6b5668efe5d19e 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 172 189 8.6E-56 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 GTHT12_RS06425 e0426923c187bd94fb6b5668efe5d19e 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 24 37 8.6E-56 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 GTHT12_RS06425 e0426923c187bd94fb6b5668efe5d19e 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 223 237 8.6E-56 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 GTHT12_RS06425 e0426923c187bd94fb6b5668efe5d19e 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 123 139 8.6E-56 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 GTHT12_RS06425 e0426923c187bd94fb6b5668efe5d19e 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 142 160 8.6E-56 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 GTHT12_RS06425 e0426923c187bd94fb6b5668efe5d19e 680 Pfam PF00771 FHIPEP family 17 669 7.6E-278 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 GTHT12_RS06425 e0426923c187bd94fb6b5668efe5d19e 680 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 6 677 2.4E-279 T 06-07-2017 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 GTHT12_RS05765 eb566422d9ebedc80aa420ab97c937b2 91 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 5 74 1.0E-31 T 06-07-2017 IPR016979 Protein of unknown function DUF2129 GTHT12_RS05765 eb566422d9ebedc80aa420ab97c937b2 91 Hamap MF_01126 UPF0298 protein . 1 78 22.427 T 06-07-2017 IPR016979 Protein of unknown function DUF2129 GTHT12_RS05765 eb566422d9ebedc80aa420ab97c937b2 91 PIRSF PIRSF031653 1 89 8.0E-35 T 06-07-2017 IPR016979 Protein of unknown function DUF2129 GTHT12_RS17515 a0a4fc5abf956ef83b8a2f3b0cee8601 72 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 13 63 1.1E-14 T 06-07-2017 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter GTHT12_RS06190 e038da9710c124f7aa3445bcf2644882 77 Pfam PF00550 Phosphopantetheine attachment site 6 73 7.7E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain GTHT12_RS06190 e038da9710c124f7aa3445bcf2644882 77 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 76 1.7E-34 T 06-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS06190 e038da9710c124f7aa3445bcf2644882 77 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 23.11 T 06-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS06190 e038da9710c124f7aa3445bcf2644882 77 SUPERFAMILY SSF47336 2 76 8.24E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain GTHT12_RS06190 e038da9710c124f7aa3445bcf2644882 77 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site GTHT12_RS06190 e038da9710c124f7aa3445bcf2644882 77 Gene3D G3DSA:1.10.1200.10 3 76 5.8E-32 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain GTHT12_RS06190 e038da9710c124f7aa3445bcf2644882 77 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 77 7.0E-13 T 06-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17750 ad5e16a9cb15139d79e9211890c8166f 217 SUPERFAMILY SSF46689 5 61 9.4E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS17750 ad5e16a9cb15139d79e9211890c8166f 217 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 2 77 4.8E-44 T 06-07-2017 IPR014243 Transcription factor, RsfA GTHT12_RS08510 a841babab87e2a2093317ddc536b3bc1 196 SUPERFAMILY SSF48498 79 195 1.27E-28 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal GTHT12_RS08510 a841babab87e2a2093317ddc536b3bc1 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 3.8E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS08510 a841babab87e2a2093317ddc536b3bc1 196 Gene3D G3DSA:1.10.357.10 1 195 1.0E-52 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 GTHT12_RS08510 a841babab87e2a2093317ddc536b3bc1 196 SUPERFAMILY SSF46689 3 82 5.08E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS08510 a841babab87e2a2093317ddc536b3bc1 196 Pfam PF13977 Bacterial transcriptional repressor 82 195 1.4E-25 T 06-07-2017 GTHT12_RS14625 e33ca3937244dd7bf46630eec1983deb 434 Pfam PF02875 Mur ligase family, glutamate ligase domain 295 376 4.7E-19 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GTHT12_RS14625 e33ca3937244dd7bf46630eec1983deb 434 SUPERFAMILY SSF51984 4 88 2.09E-20 T 06-07-2017 GTHT12_RS14625 e33ca3937244dd7bf46630eec1983deb 434 Pfam PF01225 Mur ligase family, catalytic domain 4 101 2.0E-22 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 GTHT12_RS14625 e33ca3937244dd7bf46630eec1983deb 434 SUPERFAMILY SSF53244 294 427 3.89E-35 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GTHT12_RS14625 e33ca3937244dd7bf46630eec1983deb 434 Gene3D G3DSA:3.90.190.20 297 429 2.0E-39 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GTHT12_RS14625 e33ca3937244dd7bf46630eec1983deb 434 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 4 429 1.6E-136 T 06-07-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS14625 e33ca3937244dd7bf46630eec1983deb 434 Gene3D G3DSA:3.40.1190.10 90 296 6.5E-64 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GTHT12_RS14625 e33ca3937244dd7bf46630eec1983deb 434 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 1 433 35.165 T 06-07-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS14625 e33ca3937244dd7bf46630eec1983deb 434 SUPERFAMILY SSF53623 87 293 2.09E-60 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GTHT12_RS14625 e33ca3937244dd7bf46630eec1983deb 434 Gene3D G3DSA:3.40.50.720 4 89 1.9E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS14625 e33ca3937244dd7bf46630eec1983deb 434 Pfam PF08245 Mur ligase middle domain 106 275 1.4E-26 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GTHT12_RS16340 a03fe94c6de73639e207c5b0d126ba51 516 Pfam PF00535 Glycosyl transferase family 2 6 134 9.9E-35 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 GTHT12_RS16340 a03fe94c6de73639e207c5b0d126ba51 516 SUPERFAMILY SSF53448 4 225 4.61E-58 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS16340 a03fe94c6de73639e207c5b0d126ba51 516 Gene3D G3DSA:3.90.550.10 4 201 6.2E-57 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS04600 3a981653d73524fd4c34f78a01321c0f 373 Pfam PF13439 Glycosyltransferase Family 4 13 163 1.2E-24 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 GTHT12_RS04600 3a981653d73524fd4c34f78a01321c0f 373 Gene3D G3DSA:3.40.50.2000 155 295 4.8E-10 T 06-07-2017 GTHT12_RS04600 3a981653d73524fd4c34f78a01321c0f 373 SUPERFAMILY SSF53756 2 367 3.14E-58 T 06-07-2017 GTHT12_RS04600 3a981653d73524fd4c34f78a01321c0f 373 Pfam PF00534 Glycosyl transferases group 1 173 298 7.1E-13 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 GTHT12_RS10695 25c592f5ca69a70c7b561c751de47bdf 332 Gene3D G3DSA:3.40.50.920 201 329 4.5E-43 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GTHT12_RS10695 25c592f5ca69a70c7b561c751de47bdf 332 SUPERFAMILY SSF52518 8 210 6.96E-70 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS10695 25c592f5ca69a70c7b561c751de47bdf 332 Gene3D G3DSA:3.40.50.970 7 200 1.0E-79 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS10695 25c592f5ca69a70c7b561c751de47bdf 332 Pfam PF02780 Transketolase, C-terminal domain 200 321 8.9E-40 T 06-07-2017 IPR033248 Transketolase, C-terminal domain GTHT12_RS10695 25c592f5ca69a70c7b561c751de47bdf 332 SMART SM00861 10 185 6.3E-65 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain GTHT12_RS10695 25c592f5ca69a70c7b561c751de47bdf 332 SUPERFAMILY SSF52922 195 330 5.63E-42 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GTHT12_RS10695 25c592f5ca69a70c7b561c751de47bdf 332 Pfam PF02779 Transketolase, pyrimidine binding domain 10 184 9.3E-50 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain GTHT12_RS08050 fb4c21f5f534c14872401c045c0c4339 75 TIGRFAM TIGR03090 SASP_tlp: small, acid-soluble spore protein tlp 4 70 1.1E-28 T 06-07-2017 IPR017524 Small acid-soluble spore protein, thioredoxin-like GTHT12_RS08050 fb4c21f5f534c14872401c045c0c4339 75 Hamap MF_01506 Small, acid-soluble spore protein Tlp [tlp]. 1 75 33.223 T 06-07-2017 IPR017524 Small acid-soluble spore protein, thioredoxin-like GTHT12_RS15955 cec6486a4ce020e7de73e1203b960e34 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 106 114 4.4E-72 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS15955 cec6486a4ce020e7de73e1203b960e34 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 4.4E-72 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS15955 cec6486a4ce020e7de73e1203b960e34 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 268 286 4.4E-72 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS15955 cec6486a4ce020e7de73e1203b960e34 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 4.4E-72 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS15955 cec6486a4ce020e7de73e1203b960e34 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 4.4E-72 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS15955 cec6486a4ce020e7de73e1203b960e34 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 255 4.4E-72 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS15955 cec6486a4ce020e7de73e1203b960e34 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 167 4.4E-72 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS15955 cec6486a4ce020e7de73e1203b960e34 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 140 4.4E-72 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS15955 cec6486a4ce020e7de73e1203b960e34 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 195 211 4.4E-72 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS15955 cec6486a4ce020e7de73e1203b960e34 318 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 294 1.8E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS15955 cec6486a4ce020e7de73e1203b960e34 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 2.8E-38 T 06-07-2017 GTHT12_RS15955 cec6486a4ce020e7de73e1203b960e34 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 2.8E-38 T 06-07-2017 GTHT12_RS15955 cec6486a4ce020e7de73e1203b960e34 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 2.8E-38 T 06-07-2017 GTHT12_RS15955 cec6486a4ce020e7de73e1203b960e34 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 2.8E-38 T 06-07-2017 GTHT12_RS15955 cec6486a4ce020e7de73e1203b960e34 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 2.8E-38 T 06-07-2017 GTHT12_RS15955 cec6486a4ce020e7de73e1203b960e34 318 Gene3D G3DSA:3.50.50.60 110 301 1.6E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS15955 cec6486a4ce020e7de73e1203b960e34 318 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 7 305 8.3E-123 T 06-07-2017 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 GTHT12_RS15955 cec6486a4ce020e7de73e1203b960e34 318 Gene3D G3DSA:3.50.50.60 4 109 6.7E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS15955 cec6486a4ce020e7de73e1203b960e34 318 SUPERFAMILY SSF51905 4 302 1.83E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS15955 cec6486a4ce020e7de73e1203b960e34 318 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 135 155 - T 06-07-2017 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 GTHT12_RS13360 eb438c6d528fdec885d94a4bb5e46ed8 363 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 16 360 3.2E-107 T 06-07-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like GTHT12_RS13360 eb438c6d528fdec885d94a4bb5e46ed8 363 Gene3D G3DSA:3.30.160.60 331 360 6.3E-8 T 06-07-2017 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 GTHT12_RS13360 eb438c6d528fdec885d94a4bb5e46ed8 363 Pfam PF02618 YceG-like family 57 357 3.5E-80 T 06-07-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like GTHT12_RS13610 dbae63f437e41caa64376c268cc8e18b 147 PIRSF PIRSF025624 1 145 3.8E-56 T 06-07-2017 IPR008310 UPF0735 ACT domain-containing protein GO:0009094 GTHT12_RS13610 dbae63f437e41caa64376c268cc8e18b 147 Gene3D G3DSA:3.30.70.260 68 140 2.5E-11 T 06-07-2017 GTHT12_RS13610 dbae63f437e41caa64376c268cc8e18b 147 SUPERFAMILY SSF55021 68 142 1.78E-11 T 06-07-2017 GTHT12_RS13610 dbae63f437e41caa64376c268cc8e18b 147 Pfam PF01842 ACT domain 69 133 1.6E-9 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 GTHT12_RS13610 dbae63f437e41caa64376c268cc8e18b 147 Hamap MF_00707 UPF0735 ACT domain-containing protein . 1 145 31.627 T 06-07-2017 IPR008310 UPF0735 ACT domain-containing protein GO:0009094 GTHT12_RS11630 0401900060ff7f0180134e582b57039b 268 Gene3D G3DSA:3.20.20.70 6 259 2.9E-94 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS11630 0401900060ff7f0180134e582b57039b 268 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 7 256 2.1E-88 T 06-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 GTHT12_RS11630 0401900060ff7f0180134e582b57039b 268 SUPERFAMILY SSF51366 6 234 5.65E-81 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 GTHT12_RS11630 0401900060ff7f0180134e582b57039b 268 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 39 52 - T 06-07-2017 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 GTHT12_RS11630 0401900060ff7f0180134e582b57039b 268 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 5 260 36.751 T 06-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 GTHT12_RS11630 0401900060ff7f0180134e582b57039b 268 Pfam PF00290 Tryptophan synthase alpha chain 6 249 1.3E-90 T 06-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 GTHT12_RS07230 aed58293ae550e7db83882a2d6fd0679 501 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 4 492 54.892 T 06-07-2017 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 GTHT12_RS07230 aed58293ae550e7db83882a2d6fd0679 501 SUPERFAMILY SSF51905 6 274 1.89E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS07230 aed58293ae550e7db83882a2d6fd0679 501 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 8 490 2.7E-225 T 06-07-2017 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 GTHT12_RS07230 aed58293ae550e7db83882a2d6fd0679 501 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 7 492 8.3E-243 T 06-07-2017 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 GTHT12_RS07230 aed58293ae550e7db83882a2d6fd0679 501 Gene3D G3DSA:3.50.50.60 7 74 4.7E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS07230 aed58293ae550e7db83882a2d6fd0679 501 Gene3D G3DSA:3.50.50.60 149 329 4.7E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS12975 7a05521c931d4e8bd2588eae9b8f78c3 436 Hamap MF_01494 DEAD-box ATP-dependent RNA helicase CshB [cshB]. 4 436 50.425 T 06-07-2017 IPR030881 DEAD-box ATP-dependent RNA helicase CshB GO:0004386|GO:0009409 GTHT12_RS12975 7a05521c931d4e8bd2588eae9b8f78c3 436 Gene3D G3DSA:3.40.50.300 4 213 1.2E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12975 7a05521c931d4e8bd2588eae9b8f78c3 436 Pfam PF00271 Helicase conserved C-terminal domain 233 341 4.9E-27 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS12975 7a05521c931d4e8bd2588eae9b8f78c3 436 SUPERFAMILY SSF52540 73 361 5.21E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12975 7a05521c931d4e8bd2588eae9b8f78c3 436 Pfam PF00270 DEAD/DEAH box helicase 28 196 5.4E-42 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 GTHT12_RS12975 7a05521c931d4e8bd2588eae9b8f78c3 436 SMART SM00490 260 341 1.9E-29 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS12975 7a05521c931d4e8bd2588eae9b8f78c3 436 SMART SM00487 23 224 1.3E-52 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain GTHT12_RS12975 7a05521c931d4e8bd2588eae9b8f78c3 436 Gene3D G3DSA:3.40.50.300 214 368 6.4E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS04410 80c0a415a3abc2ee95174c11cd490c49 245 Hamap MF_01443 Bis(5'-nucleosyl)-tetraphosphatase PrpE [asymmetrical] [prpE]. 1 245 60.256 T 06-07-2017 IPR023937 Bis(5'-nucleosyl)-tetraphosphatase PrpE GO:0004081|GO:0016151 KEGG: 00230+3.6.1.17|KEGG: 00240+3.6.1.17 GTHT12_RS04410 80c0a415a3abc2ee95174c11cd490c49 245 Gene3D G3DSA:3.60.21.10 1 231 1.6E-44 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like GTHT12_RS04410 80c0a415a3abc2ee95174c11cd490c49 245 Pfam PF00149 Calcineurin-like phosphoesterase 1 195 2.1E-12 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 GTHT12_RS04410 80c0a415a3abc2ee95174c11cd490c49 245 SUPERFAMILY SSF56300 1 219 8.42E-41 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like GTHT12_RS14810 3cda31afd5690fee37dd56dd8b3925f9 269 Gene3D G3DSA:1.10.3720.10 72 266 9.4E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS14810 3cda31afd5690fee37dd56dd8b3925f9 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 265 6.0E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS14810 3cda31afd5690fee37dd56dd8b3925f9 269 SUPERFAMILY SSF161098 73 253 2.09E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS06945 b0db57ef807714bb016c0a19d2a7dd1d 216 Pfam PF07486 Cell Wall Hydrolase 112 214 2.3E-20 T 06-07-2017 IPR011105 Cell wall hydrolase, SleB GO:0016787 GTHT12_RS06945 b0db57ef807714bb016c0a19d2a7dd1d 216 SUPERFAMILY SSF54106 29 74 5.23E-13 T 06-07-2017 IPR018392 LysM domain GTHT12_RS06945 b0db57ef807714bb016c0a19d2a7dd1d 216 Pfam PF01476 LysM domain 32 74 6.3E-16 T 06-07-2017 IPR018392 LysM domain GTHT12_RS06945 b0db57ef807714bb016c0a19d2a7dd1d 216 SMART SM00257 31 74 5.0E-19 T 06-07-2017 IPR018392 LysM domain GTHT12_RS06945 b0db57ef807714bb016c0a19d2a7dd1d 216 Gene3D G3DSA:3.10.350.10 29 74 1.2E-19 T 06-07-2017 IPR018392 LysM domain GTHT12_RS10295 e279f59c3b404f7cb461558a8295233e 471 Gene3D G3DSA:3.40.309.10 260 442 6.0E-61 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 GTHT12_RS10295 e279f59c3b404f7cb461558a8295233e 471 SUPERFAMILY SSF53720 2 469 4.45E-156 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10295 e279f59c3b404f7cb461558a8295233e 471 Pfam PF00171 Aldehyde dehydrogenase family 9 465 2.3E-165 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10295 e279f59c3b404f7cb461558a8295233e 471 Gene3D G3DSA:3.40.605.10 2 259 7.7E-92 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS01285 fce4ac61938b09855d2091b3f684e1d5 460 Pfam PF02875 Mur ligase family, glutamate ligase domain 319 397 1.8E-17 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GTHT12_RS01285 fce4ac61938b09855d2091b3f684e1d5 460 Pfam PF01225 Mur ligase family, catalytic domain 27 101 3.2E-10 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 GTHT12_RS01285 fce4ac61938b09855d2091b3f684e1d5 460 Gene3D G3DSA:3.40.1390.10 19 94 6.1E-23 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 GTHT12_RS01285 fce4ac61938b09855d2091b3f684e1d5 460 SUPERFAMILY SSF53623 106 315 3.53E-59 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GTHT12_RS01285 fce4ac61938b09855d2091b3f684e1d5 460 SUPERFAMILY SSF63418 1 103 5.49E-25 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 GTHT12_RS01285 fce4ac61938b09855d2091b3f684e1d5 460 Gene3D G3DSA:3.40.1190.10 95 315 2.6E-74 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GTHT12_RS01285 fce4ac61938b09855d2091b3f684e1d5 460 Pfam PF08245 Mur ligase middle domain 111 298 1.2E-49 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GTHT12_RS01285 fce4ac61938b09855d2091b3f684e1d5 460 Gene3D G3DSA:3.90.190.20 318 457 9.0E-43 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GTHT12_RS01285 fce4ac61938b09855d2091b3f684e1d5 460 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 458 35.226 T 06-07-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS01285 fce4ac61938b09855d2091b3f684e1d5 460 SUPERFAMILY SSF53244 319 456 2.93E-37 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GTHT12_RS01285 fce4ac61938b09855d2091b3f684e1d5 460 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 32 454 3.6E-138 T 06-07-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 GTHT12_RS04025 dac79edb5ac44db40428f78276bc8224 255 SUPERFAMILY SSF53474 25 254 1.76E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS04025 dac79edb5ac44db40428f78276bc8224 255 Pfam PF00326 Prolyl oligopeptidase family 89 243 6.4E-12 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 GTHT12_RS04025 dac79edb5ac44db40428f78276bc8224 255 Gene3D G3DSA:3.40.50.1820 9 254 7.5E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS01425 d034bdff1fddd2fa7bcd5b7996d597fa 246 SUPERFAMILY SSF53067 2 106 1.68E-28 T 06-07-2017 GTHT12_RS01425 d034bdff1fddd2fa7bcd5b7996d597fa 246 Pfam PF00814 Glycoprotease family 31 224 4.4E-35 T 06-07-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 GTHT12_RS01425 d034bdff1fddd2fa7bcd5b7996d597fa 246 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 216 5.6E-54 T 06-07-2017 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 GTHT12_RS01425 d034bdff1fddd2fa7bcd5b7996d597fa 246 SUPERFAMILY SSF53067 108 214 1.1E-18 T 06-07-2017 GTHT12_RS01425 d034bdff1fddd2fa7bcd5b7996d597fa 246 Gene3D G3DSA:3.30.420.40 1 131 5.5E-40 T 06-07-2017 GTHT12_RS00190 3004f4ff98419f66be2b8c6ec627ce7b 249 Gene3D G3DSA:3.40.50.150 32 244 3.1E-78 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS00190 3004f4ff98419f66be2b8c6ec627ce7b 249 Pfam PF05175 Methyltransferase small domain 18 129 1.6E-11 T 06-07-2017 IPR007848 Methyltransferase small domain GO:0008168 GTHT12_RS00190 3004f4ff98419f66be2b8c6ec627ce7b 249 SUPERFAMILY SSF53335 12 198 1.76E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS14010 4801f6183ee5cf2f6dc5ed67e5cd49d1 258 SMART SM00893 21 212 7.4E-66 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 GTHT12_RS14010 4801f6183ee5cf2f6dc5ed67e5cd49d1 258 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 156 176 - T 06-07-2017 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105 GTHT12_RS14010 4801f6183ee5cf2f6dc5ed67e5cd49d1 258 Pfam PF01012 Electron transfer flavoprotein domain 23 207 3.1E-52 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 GTHT12_RS14010 4801f6183ee5cf2f6dc5ed67e5cd49d1 258 PIRSF PIRSF000090 1 258 1.0E-82 T 06-07-2017 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105 GTHT12_RS14010 4801f6183ee5cf2f6dc5ed67e5cd49d1 258 Gene3D G3DSA:3.40.50.620 1 254 2.6E-91 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS14010 4801f6183ee5cf2f6dc5ed67e5cd49d1 258 SUPERFAMILY SSF52402 1 245 2.89E-80 T 06-07-2017 GTHT12_RS02970 7cad650662c08e571bd671e243db1e7c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 5.7E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS02970 7cad650662c08e571bd671e243db1e7c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 5.7E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS02970 7cad650662c08e571bd671e243db1e7c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 5.7E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS02970 7cad650662c08e571bd671e243db1e7c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 5.7E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS02970 7cad650662c08e571bd671e243db1e7c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 5.7E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS02970 7cad650662c08e571bd671e243db1e7c 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 5.7E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS02970 7cad650662c08e571bd671e243db1e7c 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.9E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS02970 7cad650662c08e571bd671e243db1e7c 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.9E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS02970 7cad650662c08e571bd671e243db1e7c 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.9E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS02970 7cad650662c08e571bd671e243db1e7c 249 Gene3D G3DSA:3.40.50.720 2 247 5.1E-84 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS02970 7cad650662c08e571bd671e243db1e7c 249 SUPERFAMILY SSF51735 3 247 4.57E-83 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS02970 7cad650662c08e571bd671e243db1e7c 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 244 2.6E-68 T 06-07-2017 GTHT12_RS00690 888e31fcebf44e965107c40d6505ad6e 218 SUPERFAMILY SSF54821 106 205 1.44E-39 T 06-07-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00690 888e31fcebf44e965107c40d6505ad6e 218 Gene3D G3DSA:3.30.1140.32 107 206 1.1E-45 T 06-07-2017 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00690 888e31fcebf44e965107c40d6505ad6e 218 Pfam PF07650 KH domain 37 109 1.5E-22 T 06-07-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00690 888e31fcebf44e965107c40d6505ad6e 218 SMART SM00322 59 124 1.3E-9 T 06-07-2017 IPR004087 K Homology domain GO:0003676 GTHT12_RS00690 888e31fcebf44e965107c40d6505ad6e 218 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 4.0E-41 T 06-07-2017 GTHT12_RS00690 888e31fcebf44e965107c40d6505ad6e 218 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 6.1E-98 T 06-07-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 GTHT12_RS00690 888e31fcebf44e965107c40d6505ad6e 218 SUPERFAMILY SSF54814 2 105 5.76E-40 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 GTHT12_RS00690 888e31fcebf44e965107c40d6505ad6e 218 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 06-07-2017 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00690 888e31fcebf44e965107c40d6505ad6e 218 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 39.339 T 06-07-2017 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 GTHT12_RS00690 888e31fcebf44e965107c40d6505ad6e 218 Gene3D G3DSA:3.30.300.20 17 106 4.1E-36 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta GTHT12_RS16650 4ad9a08c872bd54e7729fc8c02f4fec7 310 Gene3D G3DSA:3.40.50.2300 159 310 7.6E-58 T 06-07-2017 GTHT12_RS16650 4ad9a08c872bd54e7729fc8c02f4fec7 310 Pfam PF13407 Periplasmic binding protein domain 43 292 4.8E-72 T 06-07-2017 IPR025997 Periplasmic binding protein GTHT12_RS16650 4ad9a08c872bd54e7729fc8c02f4fec7 310 Gene3D G3DSA:3.40.50.2300 40 158 1.0E-44 T 06-07-2017 GTHT12_RS16650 4ad9a08c872bd54e7729fc8c02f4fec7 310 SUPERFAMILY SSF53822 38 310 3.88E-94 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS08550 f551f9ef96da27ea269ae5a78f748953 389 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 387 3.8E-149 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 GTHT12_RS08550 f551f9ef96da27ea269ae5a78f748953 389 ProSitePatterns PS00737 Thiolases signature 2. 335 351 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 GTHT12_RS08550 f551f9ef96da27ea269ae5a78f748953 389 PIRSF PIRSF000429 1 389 2.8E-138 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 GTHT12_RS08550 f551f9ef96da27ea269ae5a78f748953 389 Gene3D G3DSA:3.40.47.10 190 272 8.3E-73 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS08550 f551f9ef96da27ea269ae5a78f748953 389 Gene3D G3DSA:3.40.47.10 4 122 8.3E-73 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS08550 f551f9ef96da27ea269ae5a78f748953 389 Gene3D G3DSA:3.40.47.10 273 388 1.1E-65 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS08550 f551f9ef96da27ea269ae5a78f748953 389 Gene3D G3DSA:3.40.47.10 148 189 1.1E-65 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS08550 f551f9ef96da27ea269ae5a78f748953 389 Pfam PF02803 Thiolase, C-terminal domain 267 388 6.2E-49 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 GTHT12_RS08550 f551f9ef96da27ea269ae5a78f748953 389 ProSitePatterns PS00099 Thiolases active site. 370 383 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 GTHT12_RS08550 f551f9ef96da27ea269ae5a78f748953 389 SUPERFAMILY SSF53901 4 266 1.96E-81 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS08550 f551f9ef96da27ea269ae5a78f748953 389 SUPERFAMILY SSF53901 267 388 5.05E-45 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS08550 f551f9ef96da27ea269ae5a78f748953 389 Pfam PF00108 Thiolase, N-terminal domain 6 259 4.9E-81 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 GTHT12_RS11590 37289c5b57b933fc95c3bbda49512622 224 Gene3D G3DSA:1.20.810.10 6 223 2.7E-73 T 06-07-2017 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 GTHT12_RS11590 37289c5b57b933fc95c3bbda49512622 224 Pfam PF00033 Cytochrome b/b6/petB 40 219 1.9E-50 T 06-07-2017 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 GTHT12_RS11590 37289c5b57b933fc95c3bbda49512622 224 PIRSF PIRSF000032 2 224 2.4E-102 T 06-07-2017 IPR023530 Cytochrome b6, PetB GO:0005506|GO:0016021|GO:0020037|GO:0022900|GO:0045158 GTHT12_RS11590 37289c5b57b933fc95c3bbda49512622 224 SUPERFAMILY SSF81342 6 224 3.77E-62 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 GTHT12_RS10020 55b5f1038c72ef1b96acb8639a117bb7 595 Gene3D G3DSA:3.30.450.20 172 284 8.6E-11 T 06-07-2017 GTHT12_RS10020 55b5f1038c72ef1b96acb8639a117bb7 595 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 479 587 5.7E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS10020 55b5f1038c72ef1b96acb8639a117bb7 595 SUPERFAMILY SSF55874 437 589 3.8E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS10020 55b5f1038c72ef1b96acb8639a117bb7 595 Gene3D G3DSA:3.30.565.10 433 590 1.4E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS10020 55b5f1038c72ef1b96acb8639a117bb7 595 Gene3D G3DSA:3.30.450.20 96 155 3.2E-4 T 06-07-2017 GTHT12_RS10020 55b5f1038c72ef1b96acb8639a117bb7 595 Pfam PF02743 Cache domain 45 279 7.0E-31 T 06-07-2017 IPR033479 Double Cache domain 1 GTHT12_RS10020 55b5f1038c72ef1b96acb8639a117bb7 595 SUPERFAMILY SSF158472 317 367 4.58E-11 T 06-07-2017 GTHT12_RS10020 55b5f1038c72ef1b96acb8639a117bb7 595 SMART SM00387 474 592 0.0015 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS10020 55b5f1038c72ef1b96acb8639a117bb7 595 Pfam PF06580 Histidine kinase 380 459 1.1E-25 T 06-07-2017 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 GTHT12_RS10020 55b5f1038c72ef1b96acb8639a117bb7 595 Pfam PF00672 HAMP domain 300 364 1.3E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS10020 55b5f1038c72ef1b96acb8639a117bb7 595 SMART SM00304 316 368 3.4E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS03365 9d5424ed10013b110248838cf10f55b8 299 SUPERFAMILY SSF55120 78 290 8.16E-67 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS03365 9d5424ed10013b110248838cf10f55b8 299 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 17 288 2.5E-75 T 06-07-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS03365 9d5424ed10013b110248838cf10f55b8 299 Pfam PF00849 RNA pseudouridylate synthase 92 243 9.2E-33 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS00685 8341841acda1d71b39abd293d45545a9 113 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 06-07-2017 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00685 8341841acda1d71b39abd293d45545a9 113 SUPERFAMILY SSF54843 1 112 5.36E-45 T 06-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00685 8341841acda1d71b39abd293d45545a9 113 Gene3D G3DSA:3.90.470.10 1 112 4.3E-45 T 06-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00685 8341841acda1d71b39abd293d45545a9 113 Pfam PF00237 Ribosomal protein L22p/L17e 8 107 4.2E-33 T 06-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00685 8341841acda1d71b39abd293d45545a9 113 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 3.8E-52 T 06-07-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00685 8341841acda1d71b39abd293d45545a9 113 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 30.433 T 06-07-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS08210 60d4b2b0da16243cb7a2d172761befda 262 Gene3D G3DSA:3.40.630.30 131 256 1.1E-23 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS08210 60d4b2b0da16243cb7a2d172761befda 262 Pfam PF12746 GNAT acetyltransferase 177 260 2.8E-11 T 06-07-2017 IPR027365 GNAT acetyltransferase YdfB-like GTHT12_RS08210 60d4b2b0da16243cb7a2d172761befda 262 SUPERFAMILY SSF55729 132 261 4.29E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS07350 eae4a0e8e59398c2f7fb9e5b12c6fd54 319 SUPERFAMILY SSF53807 43 307 1.22E-68 T 06-07-2017 GTHT12_RS07350 eae4a0e8e59398c2f7fb9e5b12c6fd54 319 Pfam PF01497 Periplasmic binding protein 64 295 4.4E-35 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 GTHT12_RS07350 eae4a0e8e59398c2f7fb9e5b12c6fd54 319 Gene3D G3DSA:3.40.50.1980 169 318 5.8E-35 T 06-07-2017 GTHT12_RS07350 eae4a0e8e59398c2f7fb9e5b12c6fd54 319 Gene3D G3DSA:3.40.50.1980 43 168 2.0E-33 T 06-07-2017 GTHT12_RS07465 67e3240f9c33dee6994f2d60b7b18d27 249 Hamap MF_01240 UPF0309 protein . 1 243 44.402 T 06-07-2017 IPR022951 Uncharacterised protein family UPF0309 GTHT12_RS07465 67e3240f9c33dee6994f2d60b7b18d27 249 Gene3D G3DSA:3.40.50.10490 2 239 4.0E-86 T 06-07-2017 GTHT12_RS07465 67e3240f9c33dee6994f2d60b7b18d27 249 Pfam PF13580 SIS domain 4 139 2.2E-45 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 GTHT12_RS07465 67e3240f9c33dee6994f2d60b7b18d27 249 SUPERFAMILY SSF53697 2 198 5.06E-26 T 06-07-2017 GTHT12_RS07560 85a74c677730a9f715f3134850866746 270 Gene3D G3DSA:3.40.50.300 3 235 7.1E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07560 85a74c677730a9f715f3134850866746 270 SUPERFAMILY SSF52540 4 231 2.88E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07560 85a74c677730a9f715f3134850866746 270 SMART SM00382 28 225 1.2E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS07560 85a74c677730a9f715f3134850866746 270 Pfam PF00005 ABC transporter 20 167 8.6E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS07560 85a74c677730a9f715f3134850866746 270 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS11190 db9ae1de85478241b5b3c94434251452 60 Pfam PF08141 Small acid-soluble spore protein H family 1 58 2.6E-26 T 06-07-2017 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 GTHT12_RS11190 db9ae1de85478241b5b3c94434251452 60 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 1 58 9.7E-29 T 06-07-2017 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 GTHT12_RS11190 db9ae1de85478241b5b3c94434251452 60 ProDom PD052450 H SPORE ACID-SOLUBLE SMALL SASP SPORULATION SMALL PROTEIN-RELATED SOLUBLE RBL04815 1 59 5.0E-28 T 06-07-2017 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 GTHT12_RS11190 db9ae1de85478241b5b3c94434251452 60 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 59 20.386 T 06-07-2017 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 GTHT12_RS09950 b66acf7c2df26f76f846ab3e79f18d10 269 Pfam PF13242 HAD-hyrolase-like 184 259 1.9E-21 T 06-07-2017 GTHT12_RS09950 b66acf7c2df26f76f846ab3e79f18d10 269 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 10 234 3.1E-39 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA GTHT12_RS09950 b66acf7c2df26f76f846ab3e79f18d10 269 Gene3D G3DSA:3.40.50.1000 4 83 8.3E-44 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS09950 b66acf7c2df26f76f846ab3e79f18d10 269 Gene3D G3DSA:3.40.50.1000 184 262 8.3E-44 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS09950 b66acf7c2df26f76f846ab3e79f18d10 269 Gene3D G3DSA:3.40.50.10410 90 183 9.7E-24 T 06-07-2017 IPR023215 Nitrophenylphosphatase-like domain GTHT12_RS09950 b66acf7c2df26f76f846ab3e79f18d10 269 Pfam PF13344 Haloacid dehalogenase-like hydrolase 10 108 3.0E-25 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA GTHT12_RS09950 b66acf7c2df26f76f846ab3e79f18d10 269 SUPERFAMILY SSF56784 7 260 1.1E-61 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS09950 b66acf7c2df26f76f846ab3e79f18d10 269 PIRSF PIRSF000915 2 266 2.8E-53 T 06-07-2017 IPR006357 HAD-superfamily hydrolase, subfamily IIA GTHT12_RS18900 ab9c4873f2e03d0fcfc99af2852ae47f 211 Pfam PF02923 Restriction endonuclease BamHI 22 167 1.8E-37 T 06-07-2017 IPR004194 Restriction endonuclease, type II, BamHI GTHT12_RS18900 ab9c4873f2e03d0fcfc99af2852ae47f 211 PIRSF PIRSF009309 1 211 1.2E-90 T 06-07-2017 IPR004194 Restriction endonuclease, type II, BamHI GTHT12_RS18900 ab9c4873f2e03d0fcfc99af2852ae47f 211 Gene3D G3DSA:3.40.91.20 5 210 3.4E-74 T 06-07-2017 IPR011338 Restriction endonuclease, type II, BamHI/BglIII/BstY GO:0000287|GO:0003677|GO:0009036|GO:0009307 GTHT12_RS18900 ab9c4873f2e03d0fcfc99af2852ae47f 211 SUPERFAMILY SSF52980 1 209 4.83E-59 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 GTHT12_RS10480 775ac60f1a8a95b6ceadf0b04899b010 274 Gene3D G3DSA:3.40.50.620 18 174 3.7E-30 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS10480 775ac60f1a8a95b6ceadf0b04899b010 274 TIGRFAM TIGR00268 TIGR00268: TIGR00268 family protein 9 262 2.3E-79 T 06-07-2017 IPR005232 Conserved hypothetical protein CHP00268 GTHT12_RS10480 775ac60f1a8a95b6ceadf0b04899b010 274 Pfam PF02540 NAD synthase 20 84 5.2E-9 T 06-07-2017 IPR022310 NAD/GMP synthase GTHT12_RS10480 775ac60f1a8a95b6ceadf0b04899b010 274 PIRSF PIRSF006661 2 273 1.6E-102 T 06-07-2017 IPR005232 Conserved hypothetical protein CHP00268 GTHT12_RS10480 775ac60f1a8a95b6ceadf0b04899b010 274 SUPERFAMILY SSF52402 19 224 2.43E-36 T 06-07-2017 GTHT12_RS14795 059a1f97dcfcf4df7a7add651b13e616 262 SUPERFAMILY SSF53474 9 258 3.48E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS14795 059a1f97dcfcf4df7a7add651b13e616 262 Pfam PF00326 Prolyl oligopeptidase family 69 258 3.8E-21 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 GTHT12_RS14795 059a1f97dcfcf4df7a7add651b13e616 262 Gene3D G3DSA:3.40.50.1820 26 258 6.4E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS10560 d6b79bc9617d9fa963adccc2e97f1705 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 256 6.5E-67 T 06-07-2017 GTHT12_RS10560 d6b79bc9617d9fa963adccc2e97f1705 258 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 5 258 2.9E-105 T 06-07-2017 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 GTHT12_RS10560 d6b79bc9617d9fa963adccc2e97f1705 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 4.7E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS10560 d6b79bc9617d9fa963adccc2e97f1705 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 4.7E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS10560 d6b79bc9617d9fa963adccc2e97f1705 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 4.7E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS10560 d6b79bc9617d9fa963adccc2e97f1705 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GTHT12_RS10560 d6b79bc9617d9fa963adccc2e97f1705 258 SUPERFAMILY SSF51735 3 257 6.16E-84 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS10560 d6b79bc9617d9fa963adccc2e97f1705 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS10560 d6b79bc9617d9fa963adccc2e97f1705 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 2.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS10560 d6b79bc9617d9fa963adccc2e97f1705 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS10560 d6b79bc9617d9fa963adccc2e97f1705 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS10560 d6b79bc9617d9fa963adccc2e97f1705 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS10560 d6b79bc9617d9fa963adccc2e97f1705 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.3E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS10560 d6b79bc9617d9fa963adccc2e97f1705 258 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 184 4.1E-4 T 06-07-2017 GTHT12_RS10560 d6b79bc9617d9fa963adccc2e97f1705 258 Gene3D G3DSA:3.40.50.720 2 257 3.3E-85 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS12990 a900dcf7dd995a7762b0e9f73c5b7270 373 Gene3D G3DSA:3.40.1390.30 241 332 4.8E-42 T 06-07-2017 GTHT12_RS12990 a900dcf7dd995a7762b0e9f73c5b7270 373 Gene3D G3DSA:3.40.1390.30 118 133 4.8E-42 T 06-07-2017 GTHT12_RS12990 a900dcf7dd995a7762b0e9f73c5b7270 373 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 9 351 1.6E-79 T 06-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 GTHT12_RS12990 a900dcf7dd995a7762b0e9f73c5b7270 373 Gene3D G3DSA:3.30.70.830 135 239 5.6E-45 T 06-07-2017 GTHT12_RS12990 a900dcf7dd995a7762b0e9f73c5b7270 373 Gene3D G3DSA:3.40.1390.30 9 117 2.1E-47 T 06-07-2017 GTHT12_RS12990 a900dcf7dd995a7762b0e9f73c5b7270 373 SUPERFAMILY SSF102705 9 372 1.83E-134 T 06-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 GTHT12_RS12990 a900dcf7dd995a7762b0e9f73c5b7270 373 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 9 369 3.3E-84 T 06-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 GTHT12_RS12990 a900dcf7dd995a7762b0e9f73c5b7270 373 PIRSF PIRSF037489 6 373 1.1E-158 T 06-07-2017 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria GTHT12_RS09470 b78eaf4692f8509365178d3e234a4e0f 241 Pfam PF02361 Cobalt transport protein 15 205 3.7E-22 T 06-07-2017 IPR003339 ABC/ECF transporter, transmembrane component GTHT12_RS03675 fa47d77c209a30c312579e81e04e2257 404 Pfam PF05975 Bacterial ABC transporter protein EcsB 6 383 1.0E-110 T 06-07-2017 IPR010288 Bacterial ABC transporter EcsB GO:0016021 GTHT12_RS03675 fa47d77c209a30c312579e81e04e2257 404 PIRSF PIRSF037259 2 403 1.3E-120 T 06-07-2017 IPR010288 Bacterial ABC transporter EcsB GO:0016021 GTHT12_RS11495 4df101a1746342a7fb1d04c4f782ef58 393 Gene3D G3DSA:3.40.640.10 44 273 5.4E-83 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS11495 4df101a1746342a7fb1d04c4f782ef58 393 Gene3D G3DSA:3.90.1150.10 274 391 2.5E-45 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS11495 4df101a1746342a7fb1d04c4f782ef58 393 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 GTHT12_RS11495 4df101a1746342a7fb1d04c4f782ef58 393 SUPERFAMILY SSF53383 1 390 4.12E-122 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS11495 4df101a1746342a7fb1d04c4f782ef58 393 Pfam PF00155 Aminotransferase class I and II 31 385 3.2E-82 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 GTHT12_RS11495 4df101a1746342a7fb1d04c4f782ef58 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 92 112 7.7E-16 T 06-07-2017 GTHT12_RS11495 4df101a1746342a7fb1d04c4f782ef58 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 114 135 7.7E-16 T 06-07-2017 GTHT12_RS11495 4df101a1746342a7fb1d04c4f782ef58 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 197 220 7.7E-16 T 06-07-2017 GTHT12_RS11495 4df101a1746342a7fb1d04c4f782ef58 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 228 252 7.7E-16 T 06-07-2017 GTHT12_RS11495 4df101a1746342a7fb1d04c4f782ef58 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 161 185 7.7E-16 T 06-07-2017 GTHT12_RS04075 5fdaae9d867cb8b9d9e32099f7fa2549 200 SUPERFAMILY SSF53448 12 198 8.23E-30 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS04075 5fdaae9d867cb8b9d9e32099f7fa2549 200 Pfam PF12804 MobA-like NTP transferase domain 14 170 3.2E-33 T 06-07-2017 IPR025877 MobA-like NTP transferase GTHT12_RS04075 5fdaae9d867cb8b9d9e32099f7fa2549 200 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 10 188 23.48 T 06-07-2017 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 MetaCyc: PWY-5964|MetaCyc: PWY-7639 GTHT12_RS04075 5fdaae9d867cb8b9d9e32099f7fa2549 200 Gene3D G3DSA:3.90.550.10 8 199 7.5E-47 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS01625 b4d2a1e545f8515e906dde3e26b3617c 470 SUPERFAMILY SSF56235 12 235 1.54E-66 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal GTHT12_RS01625 b4d2a1e545f8515e906dde3e26b3617c 470 Gene3D G3DSA:3.40.50.2020 268 433 1.1E-44 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS01625 b4d2a1e545f8515e906dde3e26b3617c 470 Pfam PF13537 Glutamine amidotransferase domain 94 208 2.1E-20 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain GTHT12_RS01625 b4d2a1e545f8515e906dde3e26b3617c 470 Pfam PF00156 Phosphoribosyl transferase domain 272 381 6.7E-7 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 GTHT12_RS01625 b4d2a1e545f8515e906dde3e26b3617c 470 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 12 456 8.4E-165 T 06-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 GTHT12_RS01625 b4d2a1e545f8515e906dde3e26b3617c 470 SUPERFAMILY SSF53271 246 461 6.69E-74 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS01625 b4d2a1e545f8515e906dde3e26b3617c 470 Gene3D G3DSA:3.60.20.10 12 253 1.8E-64 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal GTHT12_RS01625 b4d2a1e545f8515e906dde3e26b3617c 470 PIRSF PIRSF000485 8 468 9.4E-180 T 06-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 GTHT12_RS01625 b4d2a1e545f8515e906dde3e26b3617c 470 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 11 457 47.312 T 06-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 GTHT12_RS18490 a1f162340f14d617964a8bfd5689a341 326 SMART SM00382 40 229 1.1E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS18490 a1f162340f14d617964a8bfd5689a341 326 SUPERFAMILY SSF52540 5 243 2.82E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18490 a1f162340f14d617964a8bfd5689a341 326 Gene3D G3DSA:3.40.50.300 4 240 3.2E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18490 a1f162340f14d617964a8bfd5689a341 326 Pfam PF00005 ABC transporter 31 175 5.1E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS08095 6e84378ab4cbdd78a86840e8b0a1642f 72 Hamap MF_01538 UPF0346 protein . 1 71 24.807 T 06-07-2017 IPR010673 Protein of unknown function UPF0346 GTHT12_RS08095 6e84378ab4cbdd78a86840e8b0a1642f 72 Pfam PF06855 YozE SAM-like fold 4 69 1.0E-26 T 06-07-2017 IPR023089 YozE SAM-like domain GTHT12_RS08095 6e84378ab4cbdd78a86840e8b0a1642f 72 SUPERFAMILY SSF140652 2 71 3.14E-28 T 06-07-2017 IPR023089 YozE SAM-like domain GTHT12_RS08095 6e84378ab4cbdd78a86840e8b0a1642f 72 PIRSF PIRSF037262 1 72 3.1E-34 T 06-07-2017 IPR010673 Protein of unknown function UPF0346 GTHT12_RS08095 6e84378ab4cbdd78a86840e8b0a1642f 72 Gene3D G3DSA:1.10.150.260 1 71 7.7E-33 T 06-07-2017 IPR023089 YozE SAM-like domain GTHT12_RS06605 a94b2a31ff62aab475630f1a4b1a87ff 202 Pfam PF02441 Flavoprotein 9 136 1.7E-18 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 GTHT12_RS06605 a94b2a31ff62aab475630f1a4b1a87ff 202 PIRSF PIRSF001390 3 197 2.3E-80 T 06-07-2017 IPR014214 Dipicolinic acid synthetase, subunit B GTHT12_RS06605 a94b2a31ff62aab475630f1a4b1a87ff 202 SUPERFAMILY SSF52507 9 194 3.27E-30 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 GTHT12_RS06605 a94b2a31ff62aab475630f1a4b1a87ff 202 Gene3D G3DSA:3.40.50.1950 6 144 3.2E-15 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 GTHT12_RS06605 a94b2a31ff62aab475630f1a4b1a87ff 202 TIGRFAM TIGR02852 spore_dpaB: dipicolinic acid synthetase, B subunit 9 195 5.4E-103 T 06-07-2017 IPR014214 Dipicolinic acid synthetase, subunit B GTHT12_RS17495 636649a59dc67ba4cb592668d52f708d 180 Hamap MF_01398 ATP synthase subunit b [atpF]. 10 173 14.718 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 GTHT12_RS17495 636649a59dc67ba4cb592668d52f708d 180 Pfam PF00430 ATP synthase B/B' CF(0) 24 154 2.8E-43 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 GTHT12_RS17495 636649a59dc67ba4cb592668d52f708d 180 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 27 172 1.0E-44 T 06-07-2017 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 GTHT12_RS17495 636649a59dc67ba4cb592668d52f708d 180 SUPERFAMILY SSF81573 80 138 2.48E-9 T 06-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain GTHT12_RS17495 636649a59dc67ba4cb592668d52f708d 180 Gene3D G3DSA:1.20.5.620 80 139 9.0E-7 T 06-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain GTHT12_RS17280 294b3b50643ad3d1156400f2ab771491 313 Gene3D G3DSA:3.90.25.10 211 232 4.1E-11 T 06-07-2017 GTHT12_RS17280 294b3b50643ad3d1156400f2ab771491 313 Gene3D G3DSA:3.90.25.10 285 308 4.1E-11 T 06-07-2017 GTHT12_RS17280 294b3b50643ad3d1156400f2ab771491 313 SUPERFAMILY SSF51735 2 308 4.19E-84 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS17280 294b3b50643ad3d1156400f2ab771491 313 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 4 306 52.337 T 06-07-2017 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00010+1.1.1.27|KEGG: 00051+1.1.1.271|KEGG: 00270+1.1.1.27|KEGG: 00520+1.1.1.271|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-66|MetaCyc: PWY-6901|Reactome: R-HSA-6787639 GTHT12_RS17280 294b3b50643ad3d1156400f2ab771491 313 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 238 8.0E-84 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 GTHT12_RS17280 294b3b50643ad3d1156400f2ab771491 313 Gene3D G3DSA:3.40.50.720 6 210 1.0E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS10720 83b48acc9a8a66a329114e5f81fd5a67 478 Gene3D G3DSA:3.30.420.10 291 446 7.2E-7 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS10720 83b48acc9a8a66a329114e5f81fd5a67 478 Pfam PF13610 DDE domain 289 438 7.6E-25 T 06-07-2017 IPR032874 DDE domain GTHT12_RS10720 83b48acc9a8a66a329114e5f81fd5a67 478 SUPERFAMILY SSF53098 290 448 7.97E-10 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS17180 83b48acc9a8a66a329114e5f81fd5a67 478 Gene3D G3DSA:3.30.420.10 291 446 7.2E-7 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS17180 83b48acc9a8a66a329114e5f81fd5a67 478 Pfam PF13610 DDE domain 289 438 7.6E-25 T 06-07-2017 IPR032874 DDE domain GTHT12_RS17180 83b48acc9a8a66a329114e5f81fd5a67 478 SUPERFAMILY SSF53098 290 448 7.97E-10 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS10760 b392240b12c06e4d2ef32efd7e5a83a4 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 GTHT12_RS10760 b392240b12c06e4d2ef32efd7e5a83a4 257 Gene3D G3DSA:1.10.12.10 200 257 9.3E-19 T 06-07-2017 IPR014748 Crontonase, C-terminal GTHT12_RS10760 b392240b12c06e4d2ef32efd7e5a83a4 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 256 3.5E-64 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 GTHT12_RS10760 b392240b12c06e4d2ef32efd7e5a83a4 257 SUPERFAMILY SSF52096 1 256 5.51E-87 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS10760 b392240b12c06e4d2ef32efd7e5a83a4 257 Gene3D G3DSA:3.90.226.10 1 197 7.8E-69 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS14005 18623e1fb4307658b9311cb9abaae527 325 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 262 288 - T 06-07-2017 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 GTHT12_RS14005 18623e1fb4307658b9311cb9abaae527 325 Pfam PF01012 Electron transfer flavoprotein domain 5 179 8.8E-44 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 GTHT12_RS14005 18623e1fb4307658b9311cb9abaae527 325 SUPERFAMILY SSF52402 4 191 1.74E-48 T 06-07-2017 GTHT12_RS14005 18623e1fb4307658b9311cb9abaae527 325 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 198 281 3.6E-36 T 06-07-2017 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 GTHT12_RS14005 18623e1fb4307658b9311cb9abaae527 325 SUPERFAMILY SSF52467 198 317 4.65E-49 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS14005 18623e1fb4307658b9311cb9abaae527 325 PIRSF PIRSF000089 1 323 1.6E-112 T 06-07-2017 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 GTHT12_RS14005 18623e1fb4307658b9311cb9abaae527 325 Gene3D G3DSA:3.40.50.620 4 190 9.0E-54 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS14005 18623e1fb4307658b9311cb9abaae527 325 Gene3D G3DSA:3.40.50.1220 192 319 3.0E-59 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS14005 18623e1fb4307658b9311cb9abaae527 325 SMART SM00893 5 190 8.4E-49 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 GTHT12_RS14615 c0d95a5fbcf2c95029f937948be7f8c9 127 Pfam PF12732 YtxH-like protein 9 66 3.6E-9 T 06-07-2017 IPR024623 Uncharacterised protein family YtxH GTHT12_RS03280 d3721a807d86f86ef6a8040d4fae95f0 221 Gene3D G3DSA:3.50.40.10 59 187 2.2E-20 T 06-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 GTHT12_RS03280 d3721a807d86f86ef6a8040d4fae95f0 221 SUPERFAMILY SSF56037 50 219 1.99E-35 T 06-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 GTHT12_RS03280 d3721a807d86f86ef6a8040d4fae95f0 221 Pfam PF03483 B3/4 domain 64 187 1.3E-18 T 06-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 GTHT12_RS03280 d3721a807d86f86ef6a8040d4fae95f0 221 SMART SM00873 62 212 8.1E-14 T 06-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 GTHT12_RS13050 f728b03c2ff911efbd05d999726caea9 117 Pfam PF01219 Prokaryotic diacylglycerol kinase 12 112 6.9E-34 T 06-07-2017 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 GTHT12_RS13050 f728b03c2ff911efbd05d999726caea9 117 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 65 76 - T 06-07-2017 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 GTHT12_RS13050 f728b03c2ff911efbd05d999726caea9 117 Gene3D G3DSA:1.10.3830.10 8 116 5.2E-40 T 06-07-2017 GTHT12_RS17460 c9af7833b942cee980792202aa863eac 170 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 46 154 3.3E-26 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17460 c9af7833b942cee980792202aa863eac 170 Gene3D G3DSA:3.40.50.700 31 158 1.0E-36 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17460 c9af7833b942cee980792202aa863eac 170 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 11 160 43.455 T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17460 c9af7833b942cee980792202aa863eac 170 SUPERFAMILY SSF56770 18 162 9.81E-68 T 06-07-2017 GTHT12_RS17460 c9af7833b942cee980792202aa863eac 170 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 20 160 1.7E-73 T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS16145 d66d435e3fc71493217fbb38a4fb1147 499 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 12 108 4.0E-26 T 06-07-2017 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 GTHT12_RS16145 d66d435e3fc71493217fbb38a4fb1147 499 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 225 484 5.1E-55 T 06-07-2017 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 GTHT12_RS16145 d66d435e3fc71493217fbb38a4fb1147 499 Pfam PF07196 Flagellin hook IN motif 129 182 1.7E-10 T 06-07-2017 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 GTHT12_RS13645 1d709bb93c6e297145bc09d73966cfc4 255 Gene3D G3DSA:2.70.70.10 130 253 5.3E-22 T 06-07-2017 GTHT12_RS13645 1d709bb93c6e297145bc09d73966cfc4 255 Pfam PF01551 Peptidase family M23 154 248 5.5E-19 T 06-07-2017 IPR016047 Peptidase M23 GTHT12_RS13645 1d709bb93c6e297145bc09d73966cfc4 255 SUPERFAMILY SSF51261 95 251 2.25E-17 T 06-07-2017 IPR011055 Duplicated hybrid motif GTHT12_RS10490 ec302876ff1f41e1644a3ca55c917161 298 SUPERFAMILY SSF56529 68 289 9.94E-36 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GTHT12_RS10490 ec302876ff1f41e1644a3ca55c917161 298 Gene3D G3DSA:3.90.850.10 77 289 6.0E-35 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GTHT12_RS10490 ec302876ff1f41e1644a3ca55c917161 298 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 111 288 6.9E-21 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GTHT12_RS13120 b500264660b3a059161eb196a47802e2 381 Gene3D G3DSA:2.10.230.10 143 216 2.0E-21 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 GTHT12_RS13120 b500264660b3a059161eb196a47802e2 381 Gene3D G3DSA:1.10.287.110 1 106 2.4E-39 T 06-07-2017 IPR001623 DnaJ domain GTHT12_RS13120 b500264660b3a059161eb196a47802e2 381 Pfam PF01556 DnaJ C terminal domain 122 339 1.6E-45 T 06-07-2017 IPR002939 Chaperone DnaJ, C-terminal GTHT12_RS13120 b500264660b3a059161eb196a47802e2 381 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 06-07-2017 IPR018253 DnaJ domain, conserved site GTHT12_RS13120 b500264660b3a059161eb196a47802e2 381 SUPERFAMILY SSF49493 115 171 5.23E-21 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 GTHT12_RS13120 b500264660b3a059161eb196a47802e2 381 SUPERFAMILY SSF49493 219 269 5.23E-21 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 GTHT12_RS13120 b500264660b3a059161eb196a47802e2 381 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 354 6.2E-147 T 06-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 GTHT12_RS13120 b500264660b3a059161eb196a47802e2 381 Gene3D G3DSA:2.60.260.20 262 340 3.3E-24 T 06-07-2017 GTHT12_RS13120 b500264660b3a059161eb196a47802e2 381 SMART SM00271 4 61 2.4E-32 T 06-07-2017 IPR001623 DnaJ domain GTHT12_RS13120 b500264660b3a059161eb196a47802e2 381 PRINTS PR00625 DnaJ domain signature 25 40 3.7E-31 T 06-07-2017 IPR001623 DnaJ domain GTHT12_RS13120 b500264660b3a059161eb196a47802e2 381 PRINTS PR00625 DnaJ domain signature 61 80 3.7E-31 T 06-07-2017 IPR001623 DnaJ domain GTHT12_RS13120 b500264660b3a059161eb196a47802e2 381 PRINTS PR00625 DnaJ domain signature 7 25 3.7E-31 T 06-07-2017 IPR001623 DnaJ domain GTHT12_RS13120 b500264660b3a059161eb196a47802e2 381 PRINTS PR00625 DnaJ domain signature 41 61 3.7E-31 T 06-07-2017 IPR001623 DnaJ domain GTHT12_RS13120 b500264660b3a059161eb196a47802e2 381 Gene3D G3DSA:2.60.260.20 217 260 1.1E-23 T 06-07-2017 GTHT12_RS13120 b500264660b3a059161eb196a47802e2 381 Gene3D G3DSA:2.60.260.20 107 142 1.1E-23 T 06-07-2017 GTHT12_RS13120 b500264660b3a059161eb196a47802e2 381 Pfam PF00684 DnaJ central domain 149 213 2.0E-14 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 GTHT12_RS13120 b500264660b3a059161eb196a47802e2 381 Pfam PF00226 DnaJ domain 5 66 4.6E-28 T 06-07-2017 IPR001623 DnaJ domain GTHT12_RS13120 b500264660b3a059161eb196a47802e2 381 SUPERFAMILY SSF46565 1 101 3.4E-37 T 06-07-2017 IPR001623 DnaJ domain GTHT12_RS13120 b500264660b3a059161eb196a47802e2 381 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 376 42.725 T 06-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 GTHT12_RS13120 b500264660b3a059161eb196a47802e2 381 SUPERFAMILY SSF57938 136 217 2.09E-19 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 GTHT12_RS13120 b500264660b3a059161eb196a47802e2 381 SUPERFAMILY SSF49493 264 350 4.97E-26 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 GTHT12_RS02540 32e17d5d3cd483cbd7ab74a91baa5586 468 Pfam PF07690 Major Facilitator Superfamily 18 409 7.6E-44 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS02540 32e17d5d3cd483cbd7ab74a91baa5586 468 Gene3D G3DSA:1.20.1250.20 13 191 4.0E-24 T 06-07-2017 GTHT12_RS02540 32e17d5d3cd483cbd7ab74a91baa5586 468 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 12 427 1.3E-89 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 GTHT12_RS02540 32e17d5d3cd483cbd7ab74a91baa5586 468 PRINTS PR01036 Tetracycline resistance protein TetB signature 16 40 1.3E-5 T 06-07-2017 GTHT12_RS02540 32e17d5d3cd483cbd7ab74a91baa5586 468 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 1.3E-5 T 06-07-2017 GTHT12_RS02540 32e17d5d3cd483cbd7ab74a91baa5586 468 PRINTS PR01036 Tetracycline resistance protein TetB signature 262 287 1.3E-5 T 06-07-2017 GTHT12_RS02540 32e17d5d3cd483cbd7ab74a91baa5586 468 PRINTS PR01036 Tetracycline resistance protein TetB signature 107 127 1.3E-5 T 06-07-2017 GTHT12_RS02540 32e17d5d3cd483cbd7ab74a91baa5586 468 Gene3D G3DSA:1.20.1250.20 263 458 5.2E-19 T 06-07-2017 GTHT12_RS02540 32e17d5d3cd483cbd7ab74a91baa5586 468 SUPERFAMILY SSF103473 248 458 6.8E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS02540 32e17d5d3cd483cbd7ab74a91baa5586 468 SUPERFAMILY SSF103473 5 194 6.8E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS10260 35983bb00b4778beb4c3e7177a0d3e90 413 Pfam PF00375 Sodium:dicarboxylate symporter family 11 394 9.0E-96 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS10260 35983bb00b4778beb4c3e7177a0d3e90 413 PRINTS PR00173 Glutamate-aspartate symporter signature 286 312 2.1E-13 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS10260 35983bb00b4778beb4c3e7177a0d3e90 413 PRINTS PR00173 Glutamate-aspartate symporter signature 7 27 2.1E-13 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS10260 35983bb00b4778beb4c3e7177a0d3e90 413 PRINTS PR00173 Glutamate-aspartate symporter signature 349 369 2.1E-13 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS10260 35983bb00b4778beb4c3e7177a0d3e90 413 PRINTS PR00173 Glutamate-aspartate symporter signature 184 203 2.1E-13 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS10260 35983bb00b4778beb4c3e7177a0d3e90 413 PRINTS PR00173 Glutamate-aspartate symporter signature 137 159 2.1E-13 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS10260 35983bb00b4778beb4c3e7177a0d3e90 413 Gene3D G3DSA:1.10.3860.10 2 398 1.5E-75 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS10260 35983bb00b4778beb4c3e7177a0d3e90 413 SUPERFAMILY SSF118215 10 394 8.37E-83 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS16800 2981ba2c8cc05d24f8da44d5aba31577 158 SUPERFAMILY SSF52949 1 151 5.55E-36 T 06-07-2017 GTHT12_RS16800 2981ba2c8cc05d24f8da44d5aba31577 158 SMART SM00506 1 133 1.5E-27 T 06-07-2017 IPR002589 Macro domain GTHT12_RS16800 2981ba2c8cc05d24f8da44d5aba31577 158 Pfam PF01661 Macro domain 20 132 8.4E-25 T 06-07-2017 IPR002589 Macro domain GTHT12_RS16800 2981ba2c8cc05d24f8da44d5aba31577 158 Gene3D G3DSA:3.40.220.10 2 149 4.2E-28 T 06-07-2017 GTHT12_RS05110 a21ba7a415f1e142a74c7e38c75e9cf0 172 Gene3D G3DSA:3.40.630.30 1 165 1.5E-54 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS05110 a21ba7a415f1e142a74c7e38c75e9cf0 172 SUPERFAMILY SSF55729 1 164 2.66E-31 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS05110 a21ba7a415f1e142a74c7e38c75e9cf0 172 Pfam PF08445 FR47-like protein 66 148 1.6E-22 T 06-07-2017 IPR013653 FR47-like GO:0016747 GTHT12_RS06935 f660cd970452e52bc4b7354a9d1fbaa3 157 Pfam PF07301 Protein of unknown function (DUF1453) 5 147 1.2E-58 T 06-07-2017 IPR009916 Protein of unknown function DUF1453 GTHT12_RS06935 f660cd970452e52bc4b7354a9d1fbaa3 157 PIRSF PIRSF021441 1 156 6.6E-68 T 06-07-2017 IPR031306 CcdC protein GTHT12_RS08425 49ccd1ed72ac361d83b345af1366514e 316 Pfam PF00294 pfkB family carbohydrate kinase 2 300 4.2E-60 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB GTHT12_RS08425 49ccd1ed72ac361d83b345af1366514e 316 Gene3D G3DSA:3.40.1190.20 1 309 5.1E-90 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS08425 49ccd1ed72ac361d83b345af1366514e 316 SUPERFAMILY SSF53613 1 308 5.92E-85 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS08425 49ccd1ed72ac361d83b345af1366514e 316 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 252 265 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 GTHT12_RS08930 7636abb0bd2a8cb15ee0582ba90ea71e 137 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 89 137 1.3E-10 T 06-07-2017 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain GTHT12_RS13065 94f22a2ddb0d64826ab2edca49efe74d 320 Gene3D G3DSA:3.40.50.300 111 315 1.6E-90 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13065 94f22a2ddb0d64826ab2edca49efe74d 320 SUPERFAMILY SSF54791 8 67 1.21E-5 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 GTHT12_RS13065 94f22a2ddb0d64826ab2edca49efe74d 320 SUPERFAMILY SSF52540 112 278 5.46E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13065 94f22a2ddb0d64826ab2edca49efe74d 320 Pfam PF02562 PhoH-like protein 113 316 8.4E-95 T 06-07-2017 IPR003714 PhoH-like protein GO:0005524 GTHT12_RS04550 ef2c43faa430e29275db65bffc3279a9 44 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 20 42 2.2E-11 T 06-07-2017 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM GTHT12_RS04550 ef2c43faa430e29275db65bffc3279a9 44 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 17 43 1.5E-13 T 06-07-2017 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM GTHT12_RS03795 0d094f838f787d2c7790cdb54b547550 392 SUPERFAMILY SSF56300 1 329 1.35E-58 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like GTHT12_RS03795 0d094f838f787d2c7790cdb54b547550 392 Pfam PF00149 Calcineurin-like phosphoesterase 1 223 2.1E-12 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 GTHT12_RS03795 0d094f838f787d2c7790cdb54b547550 392 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 276 365 6.8E-8 T 06-07-2017 IPR026843 Nuclease SbcCD subunit D, C-terminal domain GTHT12_RS03795 0d094f838f787d2c7790cdb54b547550 392 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 252 1.1E-73 T 06-07-2017 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 GTHT12_RS03795 0d094f838f787d2c7790cdb54b547550 392 Gene3D G3DSA:3.60.21.10 1 272 1.8E-70 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like GTHT12_RS02365 c82820b417a59506fdb4f1bf36088510 476 Gene3D G3DSA:1.10.1060.10 307 397 1.1E-11 T 06-07-2017 GTHT12_RS02365 c82820b417a59506fdb4f1bf36088510 476 Gene3D G3DSA:3.40.50.10420 64 128 2.6E-53 T 06-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain GTHT12_RS02365 c82820b417a59506fdb4f1bf36088510 476 Gene3D G3DSA:3.40.50.10420 190 296 2.6E-53 T 06-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain GTHT12_RS02365 c82820b417a59506fdb4f1bf36088510 476 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 18 455 4.5E-201 T 06-07-2017 IPR004452 4Fe-4S binding protein GO:0019516 GTHT12_RS02365 c82820b417a59506fdb4f1bf36088510 476 Pfam PF11870 Domain of unknown function (DUF3390) 385 471 5.9E-23 T 06-07-2017 IPR024569 4Fe-4S binding protein, C-terminal GTHT12_RS02365 c82820b417a59506fdb4f1bf36088510 476 SUPERFAMILY SSF46548 285 393 3.31E-16 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 GTHT12_RS02365 c82820b417a59506fdb4f1bf36088510 476 Pfam PF13183 4Fe-4S dicluster domain 311 377 5.5E-10 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain GTHT12_RS02365 c82820b417a59506fdb4f1bf36088510 476 SUPERFAMILY SSF100950 135 296 4.18E-39 T 06-07-2017 GTHT12_RS02365 c82820b417a59506fdb4f1bf36088510 476 SUPERFAMILY SSF100950 64 89 4.18E-39 T 06-07-2017 GTHT12_RS02365 c82820b417a59506fdb4f1bf36088510 476 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 313 324 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GTHT12_RS02365 c82820b417a59506fdb4f1bf36088510 476 Pfam PF02589 Uncharacterised ACR, YkgG family COG1556 71 295 1.3E-56 T 06-07-2017 IPR003741 LUD domain GTHT12_RS02365 c82820b417a59506fdb4f1bf36088510 476 Hamap MF_02103 Lactate utilization protein B [lutB]. 1 475 66.048 T 06-07-2017 IPR022825 Lactate utilization protein B GTHT12_RS03640 c19d09df6836bc259fbfb72262e13416 205 SUPERFAMILY SSF46785 23 134 4.62E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS03640 c19d09df6836bc259fbfb72262e13416 205 Hamap MF_01911 HTH-type transcriptional regulator Hpr [hpr]. 6 189 49.858 T 06-07-2017 IPR023488 HTH-type transcriptional regulator Hpr GTHT12_RS03640 c19d09df6836bc259fbfb72262e13416 205 Gene3D G3DSA:1.10.10.10 6 160 1.7E-37 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS03640 c19d09df6836bc259fbfb72262e13416 205 Pfam PF01047 MarR family 48 105 2.2E-14 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS03640 c19d09df6836bc259fbfb72262e13416 205 SMART SM00347 41 141 5.9E-19 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS03640 c19d09df6836bc259fbfb72262e13416 205 ProSitePatterns PS01117 MarR-type HTH domain signature. 80 114 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site GTHT12_RS15355 49c2fb2a26603eb9216d559bde245586 113 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 107 1.8E-31 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 GTHT12_RS01070 cb2b081e831a7343ffeaf7f5658d7b31 341 Gene3D G3DSA:1.10.3470.10 7 340 4.4E-101 T 06-07-2017 IPR029022 ABC transporter, BtuC-like GTHT12_RS01070 cb2b081e831a7343ffeaf7f5658d7b31 341 Pfam PF01032 FecCD transport family 20 338 1.7E-91 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 GTHT12_RS01070 cb2b081e831a7343ffeaf7f5658d7b31 341 SUPERFAMILY SSF81345 6 338 2.35E-81 T 06-07-2017 IPR029022 ABC transporter, BtuC-like GTHT12_RS08365 13b69fc84a4648b894ee45e4c28a5c7a 481 SUPERFAMILY SSF55785 143 242 1.18E-13 T 06-07-2017 IPR000014 PAS domain GTHT12_RS08365 13b69fc84a4648b894ee45e4c28a5c7a 481 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 291 479 1.6E-32 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 GTHT12_RS08365 13b69fc84a4648b894ee45e4c28a5c7a 481 Gene3D G3DSA:3.30.450.20 128 234 3.3E-12 T 06-07-2017 GTHT12_RS08365 13b69fc84a4648b894ee45e4c28a5c7a 481 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 128 240 1.4E-11 T 06-07-2017 IPR000014 PAS domain GTHT12_RS08365 13b69fc84a4648b894ee45e4c28a5c7a 481 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 16 106 3.7E-8 T 06-07-2017 IPR000014 PAS domain GTHT12_RS08365 13b69fc84a4648b894ee45e4c28a5c7a 481 Pfam PF13426 PAS domain 20 108 0.002 T 06-07-2017 IPR000014 PAS domain GTHT12_RS08365 13b69fc84a4648b894ee45e4c28a5c7a 481 Pfam PF13426 PAS domain 146 233 3.1E-7 T 06-07-2017 IPR000014 PAS domain GTHT12_RS08365 13b69fc84a4648b894ee45e4c28a5c7a 481 SMART SM00091 130 198 0.025 T 06-07-2017 IPR000014 PAS domain GTHT12_RS08365 13b69fc84a4648b894ee45e4c28a5c7a 481 SMART SM00091 7 74 9.2E-4 T 06-07-2017 IPR000014 PAS domain GTHT12_RS08365 13b69fc84a4648b894ee45e4c28a5c7a 481 SUPERFAMILY SSF81606 277 451 8.11E-6 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 GTHT12_RS08365 13b69fc84a4648b894ee45e4c28a5c7a 481 Gene3D G3DSA:3.30.450.20 15 109 2.3E-13 T 06-07-2017 GTHT12_RS08365 13b69fc84a4648b894ee45e4c28a5c7a 481 SMART SM00331 262 479 2.2E-19 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 GTHT12_RS08365 13b69fc84a4648b894ee45e4c28a5c7a 481 SUPERFAMILY SSF55785 19 109 3.4E-14 T 06-07-2017 IPR000014 PAS domain GTHT12_RS04945 b122ae9014d4921dc89a1005c107dea5 471 Pfam PF13520 Amino acid permease 27 430 4.9E-60 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 GTHT12_RS04945 b122ae9014d4921dc89a1005c107dea5 471 PIRSF PIRSF006060 15 470 5.0E-96 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 GTHT12_RS03860 b1b723c8bb992f2e70971b7b26ffb06d 302 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 93 300 5.3E-74 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GTHT12_RS03860 b1b723c8bb992f2e70971b7b26ffb06d 302 SUPERFAMILY SSF56529 81 300 6.41E-77 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GTHT12_RS03860 b1b723c8bb992f2e70971b7b26ffb06d 302 Gene3D G3DSA:3.90.850.10 86 301 8.5E-88 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GTHT12_RS12165 1eb9bb7d79a0de9d442e04c2986ca67d 143 Pfam PF13782 Stage V sporulation protein AB 28 136 6.6E-36 T 06-07-2017 IPR020144 Stage V sporulation protein AB GTHT12_RS12165 1eb9bb7d79a0de9d442e04c2986ca67d 143 ProDom PD086170 SPORULATION AB V STAGE MEMBRANE SPOVAB TRANSMEMBRANE 28 139 7.0E-53 T 06-07-2017 IPR020144 Stage V sporulation protein AB GTHT12_RS07115 8f735a8460c874a368b044d933befccf 255 PIRSF PIRSF006157 1 255 2.7E-85 T 06-07-2017 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA type GO:0008270|GO:0016701|GO:0055114 GTHT12_RS07115 8f735a8460c874a368b044d933befccf 255 Gene3D G3DSA:3.40.830.10 2 255 1.2E-83 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 GTHT12_RS07115 8f735a8460c874a368b044d933befccf 255 SUPERFAMILY SSF53213 3 255 1.96E-78 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 GTHT12_RS07115 8f735a8460c874a368b044d933befccf 255 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 5 247 8.1E-41 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 GTHT12_RS05580 4b1bc7a2bf37b7631da454029e558fb5 325 Gene3D G3DSA:3.40.50.920 198 321 2.4E-49 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GTHT12_RS05580 4b1bc7a2bf37b7631da454029e558fb5 325 Gene3D G3DSA:3.40.50.970 1 196 1.7E-80 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS05580 4b1bc7a2bf37b7631da454029e558fb5 325 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 1.3E-40 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain GTHT12_RS05580 4b1bc7a2bf37b7631da454029e558fb5 325 SMART SM00861 4 179 1.1E-66 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain GTHT12_RS05580 4b1bc7a2bf37b7631da454029e558fb5 325 Pfam PF02780 Transketolase, C-terminal domain 194 312 2.5E-41 T 06-07-2017 IPR033248 Transketolase, C-terminal domain GTHT12_RS05580 4b1bc7a2bf37b7631da454029e558fb5 325 SUPERFAMILY SSF52922 188 325 2.49E-43 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GTHT12_RS05580 4b1bc7a2bf37b7631da454029e558fb5 325 SUPERFAMILY SSF52518 3 193 1.41E-67 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS04255 e317e405f750aa12a1b519a0fc001550 61 Pfam PF11151 Protein of unknown function (DUF2929) 1 55 3.9E-21 T 06-07-2017 IPR021324 Protein of unknown function DUF2929 GTHT12_RS11135 f7d2d3d9fb6c04932ecaee6ad50c3722 359 SUPERFAMILY SSF55347 135 311 5.89E-31 T 06-07-2017 GTHT12_RS11135 f7d2d3d9fb6c04932ecaee6ad50c3722 359 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 141 203 1.4E-7 T 06-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 GTHT12_RS11135 f7d2d3d9fb6c04932ecaee6ad50c3722 359 Gene3D G3DSA:3.40.50.720 3 138 3.6E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS11135 f7d2d3d9fb6c04932ecaee6ad50c3722 359 SUPERFAMILY SSF51735 2 202 5.49E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS11135 f7d2d3d9fb6c04932ecaee6ad50c3722 359 Gene3D G3DSA:3.30.360.10 139 353 2.8E-51 T 06-07-2017 GTHT12_RS11135 f7d2d3d9fb6c04932ecaee6ad50c3722 359 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 125 1.3E-28 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 GTHT12_RS09445 6462d6b2c3f3e42c11691d7e53bf207e 215 Pfam PF02570 Precorrin-8X methylmutase 16 209 1.2E-79 T 06-07-2017 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 GTHT12_RS09445 6462d6b2c3f3e42c11691d7e53bf207e 215 Gene3D G3DSA:3.40.50.10230 10 211 9.4E-84 T 06-07-2017 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 GTHT12_RS09445 6462d6b2c3f3e42c11691d7e53bf207e 215 SUPERFAMILY SSF63965 10 211 3.66E-73 T 06-07-2017 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 GTHT12_RS17620 69eb035ecd552122ac23c9023f7a044e 173 SUPERFAMILY SSF53697 12 155 4.89E-5 T 06-07-2017 GTHT12_RS17620 69eb035ecd552122ac23c9023f7a044e 173 Gene3D G3DSA:3.40.50.10490 7 168 6.2E-6 T 06-07-2017 GTHT12_RS17620 69eb035ecd552122ac23c9023f7a044e 173 Pfam PF10740 Domain of unknown function (DUF2529) 1 169 1.2E-58 T 06-07-2017 IPR019676 Domain of unknown function (DUF2529) GTHT12_RS17920 b43cd33fed3b55bfa3079ea91097da59 240 SUPERFAMILY SSF75217 29 197 4.71E-40 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases GTHT12_RS17920 b43cd33fed3b55bfa3079ea91097da59 240 Gene3D G3DSA:3.40.1280.10 35 210 7.3E-40 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal GTHT12_RS17920 b43cd33fed3b55bfa3079ea91097da59 240 Hamap MF_02060 tRNA (guanosine(18)-2'-O)-methyltransferase [trmH]. 31 223 32.001 T 06-07-2017 IPR033671 tRNA (guanosine(18)-2'-O)-methyltransferase GO:0008168|GO:0030488 GTHT12_RS17920 b43cd33fed3b55bfa3079ea91097da59 240 Pfam PF00588 SpoU rRNA Methylase family 49 188 5.9E-30 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 GTHT12_RS07650 6ca9f1e5b6566e46bb7cbe4121ed16e3 559 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 165 264 1.6E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 GTHT12_RS07650 6ca9f1e5b6566e46bb7cbe4121ed16e3 559 Gene3D G3DSA:2.40.110.10 164 260 8.5E-26 T 06-07-2017 GTHT12_RS07650 6ca9f1e5b6566e46bb7cbe4121ed16e3 559 Gene3D G3DSA:1.20.140.10 261 437 1.2E-41 T 06-07-2017 GTHT12_RS07650 6ca9f1e5b6566e46bb7cbe4121ed16e3 559 SUPERFAMILY SSF56645 46 284 1.03E-44 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 GTHT12_RS07650 6ca9f1e5b6566e46bb7cbe4121ed16e3 559 SUPERFAMILY SSF47203 278 437 1.53E-40 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS07650 6ca9f1e5b6566e46bb7cbe4121ed16e3 559 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 275 432 2.2E-34 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS07650 6ca9f1e5b6566e46bb7cbe4121ed16e3 559 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 393 412 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 GTHT12_RS12590 2d540b0938bfe46563d1f0a925f73a59 170 PIRSF PIRSF021435 1 170 2.7E-61 T 06-07-2017 IPR014198 Stage III sporulation protein AB GTHT12_RS12590 2d540b0938bfe46563d1f0a925f73a59 170 Pfam PF09548 Stage III sporulation protein AB (spore_III_AB) 2 170 7.9E-53 T 06-07-2017 IPR014198 Stage III sporulation protein AB GTHT12_RS12590 2d540b0938bfe46563d1f0a925f73a59 170 TIGRFAM TIGR02833 spore_III_AB: stage III sporulation protein AB 2 170 2.9E-61 T 06-07-2017 IPR014198 Stage III sporulation protein AB GTHT12_RS18790 5d91442dc8b748447dcc9b7cb7d05789 411 Pfam PF00872 Transposase, Mutator family 16 376 5.6E-141 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS08795 5d91442dc8b748447dcc9b7cb7d05789 411 Pfam PF00872 Transposase, Mutator family 16 376 5.6E-141 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS05290 5d91442dc8b748447dcc9b7cb7d05789 411 Pfam PF00872 Transposase, Mutator family 16 376 5.6E-141 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS08920 5d91442dc8b748447dcc9b7cb7d05789 411 Pfam PF00872 Transposase, Mutator family 16 376 5.6E-141 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS18620 5d91442dc8b748447dcc9b7cb7d05789 411 Pfam PF00872 Transposase, Mutator family 16 376 5.6E-141 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS00985 5d91442dc8b748447dcc9b7cb7d05789 411 Pfam PF00872 Transposase, Mutator family 16 376 5.6E-141 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS03060 5d91442dc8b748447dcc9b7cb7d05789 411 Pfam PF00872 Transposase, Mutator family 16 376 5.6E-141 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS14505 5d91442dc8b748447dcc9b7cb7d05789 411 Pfam PF00872 Transposase, Mutator family 16 376 5.6E-141 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS01985 5d91442dc8b748447dcc9b7cb7d05789 411 Pfam PF00872 Transposase, Mutator family 16 376 5.6E-141 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS11575 7ed79f5fc39b648c7c929bcea07cff80 262 TIGRFAM TIGR02878 spore_ypjB: sporulation protein YpjB 28 258 6.0E-96 T 06-07-2017 IPR014231 Sporulation protein YpjB GTHT12_RS11575 7ed79f5fc39b648c7c929bcea07cff80 262 Pfam PF09577 Sporulation protein YpjB (SpoYpjB) 29 256 3.0E-88 T 06-07-2017 IPR014231 Sporulation protein YpjB GTHT12_RS05255 cc6f570e9cd8689bb225078a710a766a 116 Pfam PF11518 Protein of unknown function (DUF3221) 24 114 1.0E-13 T 06-07-2017 IPR021598 Protein of unknown function DUF3221 GTHT12_RS05255 cc6f570e9cd8689bb225078a710a766a 116 Gene3D G3DSA:2.40.50.140 33 115 2.0E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS18535 cc6f570e9cd8689bb225078a710a766a 116 Pfam PF11518 Protein of unknown function (DUF3221) 24 114 1.0E-13 T 06-07-2017 IPR021598 Protein of unknown function DUF3221 GTHT12_RS18535 cc6f570e9cd8689bb225078a710a766a 116 Gene3D G3DSA:2.40.50.140 33 115 2.0E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS01975 6306884a101ca236a0bbdaa09afa5332 98 PIRSF PIRSF033199 1 98 1.4E-51 T 06-07-2017 IPR014580 Uncharacterised conserved protein UCP033199 GTHT12_RS01975 6306884a101ca236a0bbdaa09afa5332 98 Pfam PF09966 Uncharacterized protein conserved in bacteria (DUF2200) 1 97 6.3E-49 T 06-07-2017 IPR014580 Uncharacterised conserved protein UCP033199 GTHT12_RS01975 6306884a101ca236a0bbdaa09afa5332 98 Gene3D G3DSA:1.10.8.290 1 98 1.1E-51 T 06-07-2017 IPR023204 SP1917 domain GTHT12_RS01635 581e53567d8d9d25489069b6e081245e 209 Pfam PF00551 Formyl transferase 2 182 1.6E-58 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GTHT12_RS01635 581e53567d8d9d25489069b6e081245e 209 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 134 157 - T 06-07-2017 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GTHT12_RS01635 581e53567d8d9d25489069b6e081245e 209 Gene3D G3DSA:3.40.50.170 1 193 1.1E-68 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GTHT12_RS01635 581e53567d8d9d25489069b6e081245e 209 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 2 190 8.3E-73 T 06-07-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 GTHT12_RS01635 581e53567d8d9d25489069b6e081245e 209 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 188 32.144 T 06-07-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 GTHT12_RS01635 581e53567d8d9d25489069b6e081245e 209 SUPERFAMILY SSF53328 2 188 1.09E-59 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 GTHT12_RS18210 0d03e5ac1c76e9afcf49789115239ec2 281 SUPERFAMILY SSF110849 26 122 1.31E-29 T 06-07-2017 IPR003115 ParB/Sulfiredoxin GTHT12_RS18210 0d03e5ac1c76e9afcf49789115239ec2 281 SUPERFAMILY SSF109709 113 218 6.28E-35 T 06-07-2017 GTHT12_RS18210 0d03e5ac1c76e9afcf49789115239ec2 281 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 27 280 1.8E-114 T 06-07-2017 IPR023705 Nucleoid occlusion protein GTHT12_RS18210 0d03e5ac1c76e9afcf49789115239ec2 281 SMART SM00470 29 119 2.0E-35 T 06-07-2017 IPR003115 ParB/Sulfiredoxin GTHT12_RS18210 0d03e5ac1c76e9afcf49789115239ec2 281 Hamap MF_02015 Nucleoid occlusion protein [noc]. 3 280 37.713 T 06-07-2017 IPR023705 Nucleoid occlusion protein GTHT12_RS18210 0d03e5ac1c76e9afcf49789115239ec2 281 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 26 205 7.0E-62 T 06-07-2017 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 GTHT12_RS18210 0d03e5ac1c76e9afcf49789115239ec2 281 Pfam PF02195 ParB-like nuclease domain 31 118 2.0E-27 T 06-07-2017 IPR003115 ParB/Sulfiredoxin GTHT12_RS18210 0d03e5ac1c76e9afcf49789115239ec2 281 Gene3D G3DSA:3.90.1530.10 22 125 4.2E-39 T 06-07-2017 GTHT12_RS17365 6d5b0010f4d375dc11ad29a4af7916ec 193 Pfam PF02417 Chromate transporter 4 170 7.0E-37 T 06-07-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 GTHT12_RS04290 9b32ee1c6056d0c6d7cc93ca125a0778 246 Pfam PF12227 Protein of unknown function (DUF3603) 35 246 8.5E-114 T 06-07-2017 IPR020909 UPF0736 GTHT12_RS04290 9b32ee1c6056d0c6d7cc93ca125a0778 246 Hamap MF_01860 UPF0736 protein . 1 246 51.486 T 06-07-2017 IPR020909 UPF0736 GTHT12_RS05985 61eca62f190aa4b4f42127b8081ea58d 179 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 3 178 39.173 T 06-07-2017 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 GTHT12_RS05985 61eca62f190aa4b4f42127b8081ea58d 179 Pfam PF00156 Phosphoribosyl transferase domain 8 153 1.9E-19 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 GTHT12_RS05985 61eca62f190aa4b4f42127b8081ea58d 179 SUPERFAMILY SSF53271 3 174 4.85E-44 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS05985 61eca62f190aa4b4f42127b8081ea58d 179 Gene3D G3DSA:3.40.50.2020 2 170 9.9E-56 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS01675 e73eb47420cb2f517102ed2f4003b6ef 239 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 8 223 3.2E-71 T 06-07-2017 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 GTHT12_RS01675 e73eb47420cb2f517102ed2f4003b6ef 239 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 1 239 93.619 T 06-07-2017 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 GTHT12_RS01675 e73eb47420cb2f517102ed2f4003b6ef 239 Gene3D G3DSA:3.20.20.390 3 224 7.1E-78 T 06-07-2017 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 GTHT12_RS01675 e73eb47420cb2f517102ed2f4003b6ef 239 SUPERFAMILY SSF51395 6 222 1.83E-50 T 06-07-2017 GTHT12_RS01675 e73eb47420cb2f517102ed2f4003b6ef 239 Pfam PF01884 PcrB family 3 226 5.9E-77 T 06-07-2017 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 GTHT12_RS14355 44e32062dfbb79e34531facc0268730d 553 Gene3D G3DSA:3.30.300.30 446 551 1.1E-31 T 06-07-2017 GTHT12_RS14355 44e32062dfbb79e34531facc0268730d 553 Gene3D G3DSA:2.30.38.10 365 443 8.4E-23 T 06-07-2017 GTHT12_RS14355 44e32062dfbb79e34531facc0268730d 553 SUPERFAMILY SSF56801 12 549 2.09E-162 T 06-07-2017 GTHT12_RS14355 44e32062dfbb79e34531facc0268730d 553 Pfam PF00501 AMP-binding enzyme 42 448 7.1E-98 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GTHT12_RS14355 44e32062dfbb79e34531facc0268730d 553 ProSitePatterns PS00455 Putative AMP-binding domain signature. 198 209 - T 06-07-2017 IPR020845 AMP-binding, conserved site GTHT12_RS14355 44e32062dfbb79e34531facc0268730d 553 Gene3D G3DSA:3.40.50.980 203 351 2.3E-33 T 06-07-2017 GTHT12_RS14355 44e32062dfbb79e34531facc0268730d 553 Gene3D G3DSA:3.40.50.980 41 202 3.5E-46 T 06-07-2017 GTHT12_RS14355 44e32062dfbb79e34531facc0268730d 553 Pfam PF13193 AMP-binding enzyme C-terminal domain 458 536 4.0E-25 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain GTHT12_RS15425 d3fbaeaf4c0c2eeff4dbf1c1c00c9eb0 121 Pfam PF01521 Iron-sulphur cluster biosynthesis 6 106 1.3E-22 T 06-07-2017 IPR000361 FeS cluster biogenesis GTHT12_RS15425 d3fbaeaf4c0c2eeff4dbf1c1c00c9eb0 121 Gene3D G3DSA:2.60.300.12 3 97 2.8E-33 T 06-07-2017 IPR000361 FeS cluster biogenesis GTHT12_RS15425 d3fbaeaf4c0c2eeff4dbf1c1c00c9eb0 121 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 92 109 - T 06-07-2017 IPR017870 FeS cluster insertion, C-terminal, conserved site GTHT12_RS15425 d3fbaeaf4c0c2eeff4dbf1c1c00c9eb0 121 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 6 110 5.3E-39 T 06-07-2017 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 GTHT12_RS15425 d3fbaeaf4c0c2eeff4dbf1c1c00c9eb0 121 SUPERFAMILY SSF89360 5 99 1.53E-31 T 06-07-2017 IPR000361 FeS cluster biogenesis GTHT12_RS12520 a6c92f5f131994d9e071bac52ab91222 297 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 83 99 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 GTHT12_RS12520 a6c92f5f131994d9e071bac52ab91222 297 Pfam PF00348 Polyprenyl synthetase 32 269 7.9E-61 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 GTHT12_RS12520 a6c92f5f131994d9e071bac52ab91222 297 SUPERFAMILY SSF48576 8 276 4.32E-86 T 06-07-2017 IPR008949 Isoprenoid synthase domain GTHT12_RS12520 a6c92f5f131994d9e071bac52ab91222 297 Gene3D G3DSA:1.10.600.10 5 286 1.1E-95 T 06-07-2017 IPR008949 Isoprenoid synthase domain GTHT12_RS12520 a6c92f5f131994d9e071bac52ab91222 297 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 216 228 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 GTHT12_RS01495 fc1e7e3caab904700fca6998499633e6 414 Pfam PF00999 Sodium/hydrogen exchanger family 12 376 1.1E-56 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 GTHT12_RS06855 eb372292706c5f3daf5bd1ee4952ed70 415 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 266 284 9.6E-10 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS06855 eb372292706c5f3daf5bd1ee4952ed70 415 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 199 219 9.6E-10 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS06855 eb372292706c5f3daf5bd1ee4952ed70 415 Pfam PF13167 GTP-binding GTPase N-terminal 23 111 2.4E-34 T 06-07-2017 IPR025121 GTPase HflX, N-terminal GTHT12_RS06855 eb372292706c5f3daf5bd1ee4952ed70 415 Pfam PF16360 GTP-binding GTPase Middle Region 113 191 5.9E-31 T 06-07-2017 IPR032305 GTP-binding protein, middle domain GTHT12_RS06855 eb372292706c5f3daf5bd1ee4952ed70 415 Pfam PF01926 50S ribosome-binding GTPase 198 317 2.7E-19 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS06855 eb372292706c5f3daf5bd1ee4952ed70 415 SUPERFAMILY SSF52540 197 363 8.54E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06855 eb372292706c5f3daf5bd1ee4952ed70 415 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 5 353 1.1E-145 T 06-07-2017 IPR016496 GTPase HflX GO:0005525 GTHT12_RS06855 eb372292706c5f3daf5bd1ee4952ed70 415 Hamap MF_00900 GTPase HflX [hflX]. 25 383 47.21 T 06-07-2017 IPR016496 GTPase HflX GO:0005525 GTHT12_RS06855 eb372292706c5f3daf5bd1ee4952ed70 415 PIRSF PIRSF006809 1 406 7.9E-153 T 06-07-2017 IPR016496 GTPase HflX GO:0005525 GTHT12_RS06855 eb372292706c5f3daf5bd1ee4952ed70 415 Gene3D G3DSA:3.40.50.300 195 357 8.5E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12025 722ec918496a04d0fc97ffbea04603a8 395 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 48 393 1.3E-76 T 06-07-2017 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 GTHT12_RS12025 722ec918496a04d0fc97ffbea04603a8 395 Pfam PF01578 Cytochrome C assembly protein 72 390 9.0E-33 T 06-07-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 GTHT12_RS08145 90cfc75c89b9d846eae0465ca4b312a7 296 SUPERFAMILY SSF160240 212 289 3.79E-18 T 06-07-2017 GTHT12_RS08145 90cfc75c89b9d846eae0465ca4b312a7 296 SUPERFAMILY SSF161111 11 210 4.71E-50 T 06-07-2017 GTHT12_RS08145 90cfc75c89b9d846eae0465ca4b312a7 296 Gene3D G3DSA:3.30.70.1350 210 289 3.3E-19 T 06-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain GTHT12_RS08145 90cfc75c89b9d846eae0465ca4b312a7 296 Pfam PF01545 Cation efflux family 16 208 2.2E-43 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 GTHT12_RS08145 90cfc75c89b9d846eae0465ca4b312a7 296 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 12 289 6.5E-65 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 GTHT12_RS08145 90cfc75c89b9d846eae0465ca4b312a7 296 Pfam PF16916 Dimerisation domain of Zinc Transporter 214 289 1.8E-17 T 06-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain GTHT12_RS08145 90cfc75c89b9d846eae0465ca4b312a7 296 Gene3D G3DSA:1.20.1510.10 15 208 7.7E-44 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain GTHT12_RS08375 1800a5f50e903992d896e17d6aa57520 141 Gene3D G3DSA:3.30.750.24 10 117 2.1E-18 T 06-07-2017 IPR002645 STAS domain GTHT12_RS08375 1800a5f50e903992d896e17d6aa57520 141 SUPERFAMILY SSF52091 10 116 4.12E-15 T 06-07-2017 IPR002645 STAS domain GTHT12_RS08375 1800a5f50e903992d896e17d6aa57520 141 Pfam PF13466 STAS domain 21 81 2.0E-8 T 06-07-2017 IPR002645 STAS domain GTHT12_RS08785 219f4dd603e24a6a60d7eb88a97d48df 321 TIGRFAM TIGR00629 uvde: UV damage endonuclease UvdE 4 305 1.1E-63 T 06-07-2017 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 GTHT12_RS08785 219f4dd603e24a6a60d7eb88a97d48df 321 Pfam PF03851 UV-endonuclease UvdE 6 275 4.6E-85 T 06-07-2017 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 GTHT12_RS08785 219f4dd603e24a6a60d7eb88a97d48df 321 SUPERFAMILY SSF51658 85 279 1.13E-18 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain GTHT12_RS10040 117d62bd8369364261c687aeae9121a8 486 Pfam PF00171 Aldehyde dehydrogenase family 18 480 2.5E-155 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10040 117d62bd8369364261c687aeae9121a8 486 Hamap MF_01670 Methylmalonate semialdehyde dehydrogenase [acylating] [iolA]. 4 486 73.562 T 06-07-2017 IPR023510 Methylmalonate-semialdehyde dehydrogenase, Gram-positive bacteria GO:0004491|GO:0018478|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373 GTHT12_RS10040 117d62bd8369364261c687aeae9121a8 486 Gene3D G3DSA:3.40.605.10 8 266 3.1E-103 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10040 117d62bd8369364261c687aeae9121a8 486 SUPERFAMILY SSF53720 5 485 1.7E-160 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10040 117d62bd8369364261c687aeae9121a8 486 Gene3D G3DSA:3.40.309.10 267 454 4.7E-67 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 GTHT12_RS10040 117d62bd8369364261c687aeae9121a8 486 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 11 486 1.7E-196 T 06-07-2017 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 GTHT12_RS10040 117d62bd8369364261c687aeae9121a8 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 GTHT12_RS11445 1e1704973bfd2a32c8f9aff2fd8cae2f 114 Pfam PF14179 YppG-like protein 24 112 3.5E-26 T 06-07-2017 IPR025555 YppG-like protein GTHT12_RS07235 c8c640a4fce2e81e62211796d79dc127 182 Pfam PF08858 IDEAL domain 139 175 9.8E-12 T 06-07-2017 IPR014957 IDEAL domain GTHT12_RS07235 c8c640a4fce2e81e62211796d79dc127 182 Pfam PF08864 UPF0302 domain 8 112 3.2E-31 T 06-07-2017 IPR014963 Uncharacterised domain UPF0302, N-terminal GTHT12_RS07235 c8c640a4fce2e81e62211796d79dc127 182 SMART SM00914 139 175 1.7E-11 T 06-07-2017 IPR014957 IDEAL domain GTHT12_RS07235 c8c640a4fce2e81e62211796d79dc127 182 PIRSF PIRSF007165 1 182 9.6E-42 T 06-07-2017 IPR011188 Uncharacterised protein family UPF0302 GTHT12_RS01100 aa26f163bef07bf66889e7442095b6fa 302 Pfam PF05675 Protein of unknown function (DUF817) 38 272 1.4E-105 T 06-07-2017 IPR008535 Protein of unknown function DUF817 GTHT12_RS01100 aa26f163bef07bf66889e7442095b6fa 302 PIRSF PIRSF009141 27 293 2.6E-127 T 06-07-2017 IPR008535 Protein of unknown function DUF817 GTHT12_RS05440 7991dc5e3069bd9deec4f1b1cdbf96aa 261 SUPERFAMILY SSF142823 4 238 1.22E-52 T 06-07-2017 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 GTHT12_RS05440 7991dc5e3069bd9deec4f1b1cdbf96aa 261 Gene3D G3DSA:3.90.1560.10 20 242 6.1E-58 T 06-07-2017 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 GTHT12_RS05440 7991dc5e3069bd9deec4f1b1cdbf96aa 261 Pfam PF04029 2-phosphosulpholactate phosphatase 10 238 5.1E-58 T 06-07-2017 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 GTHT12_RS12745 ada38caf6698125fe08cf8666de89c78 264 Pfam PF11079 Bacterial protein YqhG of unknown function 1 259 2.0E-124 T 06-07-2017 IPR024562 Uncharacterised protein family YqhG GTHT12_RS12745 ada38caf6698125fe08cf8666de89c78 264 ProDom PD123329 YQHG BH2818 1 259 1.0E-142 T 06-07-2017 IPR024562 Uncharacterised protein family YqhG GTHT12_RS09365 d0b8e549836b6ef334cae003868df184 383 Gene3D G3DSA:3.30.1370.70 3 90 1.1E-22 T 06-07-2017 IPR014824 Scaffold protein Nfu/NifU, N-terminal GTHT12_RS09365 d0b8e549836b6ef334cae003868df184 383 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 6 87 2.2E-19 T 06-07-2017 IPR014824 Scaffold protein Nfu/NifU, N-terminal GTHT12_RS09365 d0b8e549836b6ef334cae003868df184 383 Gene3D G3DSA:1.25.10.10 167 369 5.2E-38 T 06-07-2017 IPR011989 Armadillo-like helical GTHT12_RS09365 d0b8e549836b6ef334cae003868df184 383 SUPERFAMILY SSF110836 3 90 3.4E-22 T 06-07-2017 IPR014824 Scaffold protein Nfu/NifU, N-terminal GTHT12_RS09365 d0b8e549836b6ef334cae003868df184 383 Pfam PF13646 HEAT repeats 268 343 1.4E-15 T 06-07-2017 GTHT12_RS09365 d0b8e549836b6ef334cae003868df184 383 SUPERFAMILY SSF48371 204 377 4.94E-40 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 GTHT12_RS09365 d0b8e549836b6ef334cae003868df184 383 Pfam PF13769 Virulence factor 109 189 6.6E-28 T 06-07-2017 IPR025989 Virulence factor domain GTHT12_RS09365 d0b8e549836b6ef334cae003868df184 383 SMART SM00567 E-Z type HEAT repeats 311 340 8.8E-5 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 GTHT12_RS09365 d0b8e549836b6ef334cae003868df184 383 SMART SM00567 E-Z type HEAT repeats 219 247 37.0 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 GTHT12_RS09365 d0b8e549836b6ef334cae003868df184 383 SMART SM00567 E-Z type HEAT repeats 249 278 0.25 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 GTHT12_RS09365 d0b8e549836b6ef334cae003868df184 383 SMART SM00567 E-Z type HEAT repeats 280 309 9.0E-5 T 06-07-2017 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 GTHT12_RS09365 d0b8e549836b6ef334cae003868df184 383 SMART SM00932 4 90 4.8E-30 T 06-07-2017 IPR014824 Scaffold protein Nfu/NifU, N-terminal GTHT12_RS12490 e6b22ceba7351aaae8e315d7d5e75ee2 431 SUPERFAMILY SSF50156 141 221 2.89E-12 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS12490 e6b22ceba7351aaae8e315d7d5e75ee2 431 Gene3D G3DSA:2.30.42.10 110 200 3.2E-14 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS12490 e6b22ceba7351aaae8e315d7d5e75ee2 431 Gene3D G3DSA:2.40.10.10 320 413 0.001 T 06-07-2017 GTHT12_RS12490 e6b22ceba7351aaae8e315d7d5e75ee2 431 SUPERFAMILY SSF50494 342 414 7.72E-6 T 06-07-2017 IPR009003 Peptidase S1, PA clan GTHT12_RS12490 e6b22ceba7351aaae8e315d7d5e75ee2 431 TIGRFAM TIGR02860 spore_IV_B: stage IV sporulation protein B 4 421 7.5E-170 T 06-07-2017 IPR014219 Peptidase S55, sporulation stage IV, protein B GTHT12_RS12490 e6b22ceba7351aaae8e315d7d5e75ee2 431 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 113 188 2.7E-9 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS12490 e6b22ceba7351aaae8e315d7d5e75ee2 431 Pfam PF05580 SpoIVB peptidase S55 208 416 8.1E-86 T 06-07-2017 IPR008763 Peptidase S55, SpoIVB GTHT12_RS12490 e6b22ceba7351aaae8e315d7d5e75ee2 431 SMART SM00228 122 191 1.5E-5 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS10130 b724cda9989339461d6d3b2b9ae6cf21 336 Pfam PF00005 ABC transporter 25 181 2.0E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS10130 b724cda9989339461d6d3b2b9ae6cf21 336 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 2.6E-28 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 GTHT12_RS10130 b724cda9989339461d6d3b2b9ae6cf21 336 SUPERFAMILY SSF52540 33 316 1.45E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10130 b724cda9989339461d6d3b2b9ae6cf21 336 Gene3D G3DSA:3.40.50.300 4 256 6.8E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10130 b724cda9989339461d6d3b2b9ae6cf21 336 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS10130 b724cda9989339461d6d3b2b9ae6cf21 336 SMART SM00382 33 232 5.2E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS10130 b724cda9989339461d6d3b2b9ae6cf21 336 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 298 2.6E-20 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 GTHT12_RS09945 b61ce7cf2a1cf30c20f3f5e6f594085a 405 Gene3D G3DSA:1.20.1090.10 181 310 2.3E-62 T 06-07-2017 GTHT12_RS09945 b61ce7cf2a1cf30c20f3f5e6f594085a 405 Gene3D G3DSA:1.20.1090.10 350 401 2.3E-62 T 06-07-2017 GTHT12_RS09945 b61ce7cf2a1cf30c20f3f5e6f594085a 405 Hamap MF_00497_B Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 3 400 54.686 T 06-07-2017 IPR023003 Glycerol-1-phosphate dehydrogenase, bacteria GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|KEGG: 00630+1.1.1.26|MetaCyc: PWY-6349|MetaCyc: PWY-7294|MetaCyc: PWY-7295 GTHT12_RS09945 b61ce7cf2a1cf30c20f3f5e6f594085a 405 Pfam PF13685 Iron-containing alcohol dehydrogenase 31 297 7.3E-78 T 06-07-2017 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|KEGG: 00630+1.1.1.26|MetaCyc: PWY-6349|MetaCyc: PWY-7294|MetaCyc: PWY-7295 GTHT12_RS09945 b61ce7cf2a1cf30c20f3f5e6f594085a 405 SUPERFAMILY SSF56796 340 386 4.58E-54 T 06-07-2017 GTHT12_RS09945 b61ce7cf2a1cf30c20f3f5e6f594085a 405 SUPERFAMILY SSF56796 20 307 4.58E-54 T 06-07-2017 GTHT12_RS09945 b61ce7cf2a1cf30c20f3f5e6f594085a 405 Gene3D G3DSA:3.40.50.1970 17 179 2.0E-33 T 06-07-2017 GTHT12_RS06565 2bf9071f2639cbadad9a908e4b2a267f 302 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 1 301 19.826 T 06-07-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS06565 2bf9071f2639cbadad9a908e4b2a267f 302 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 23 178 6.8E-58 T 06-07-2017 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 GTHT12_RS06565 2bf9071f2639cbadad9a908e4b2a267f 302 SUPERFAMILY SSF55120 1 236 6.88E-82 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS06565 2bf9071f2639cbadad9a908e4b2a267f 302 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 179 237 1.3E-15 T 06-07-2017 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 GTHT12_RS06565 2bf9071f2639cbadad9a908e4b2a267f 302 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 1 216 9.2E-84 T 06-07-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 GTHT12_RS10530 6777bafb31ad8e2e556b5fd351d10263 315 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 270 283 6.6E-7 T 06-07-2017 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 GTHT12_RS10530 6777bafb31ad8e2e556b5fd351d10263 315 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 257 269 6.6E-7 T 06-07-2017 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 GTHT12_RS10530 6777bafb31ad8e2e556b5fd351d10263 315 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 109 119 6.6E-7 T 06-07-2017 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 GTHT12_RS10530 6777bafb31ad8e2e556b5fd351d10263 315 Gene3D G3DSA:3.20.20.100 1 313 5.1E-110 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain GTHT12_RS10530 6777bafb31ad8e2e556b5fd351d10263 315 Pfam PF00248 Aldo/keto reductase family 15 314 3.3E-82 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain GTHT12_RS10530 6777bafb31ad8e2e556b5fd351d10263 315 SUPERFAMILY SSF51430 1 313 1.57E-106 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain GTHT12_RS09430 85ea0271c8207f091a1a4b3f366587d0 233 SUPERFAMILY SSF53790 1 232 8.37E-50 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS09430 85ea0271c8207f091a1a4b3f366587d0 233 Gene3D G3DSA:3.40.1010.10 1 131 5.0E-38 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS09430 85ea0271c8207f091a1a4b3f366587d0 233 PIRSF PIRSF036427 1 233 5.7E-75 T 06-07-2017 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 GTHT12_RS09430 85ea0271c8207f091a1a4b3f366587d0 233 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 3 233 6.4E-81 T 06-07-2017 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 GTHT12_RS09430 85ea0271c8207f091a1a4b3f366587d0 233 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 214 1.4E-54 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS03475 060a11a4f3c01db276d2f70b9006d9f5 401 Pfam PF07690 Major Facilitator Superfamily 24 243 1.2E-31 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS03475 060a11a4f3c01db276d2f70b9006d9f5 401 SUPERFAMILY SSF103473 13 392 1.83E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS03475 060a11a4f3c01db276d2f70b9006d9f5 401 Gene3D G3DSA:1.20.1250.20 214 390 8.0E-26 T 06-07-2017 GTHT12_RS03475 060a11a4f3c01db276d2f70b9006d9f5 401 Gene3D G3DSA:1.20.1250.20 18 198 4.2E-37 T 06-07-2017 GTHT12_RS08935 9389661a952b79bf38f31719fc833b15 148 SUPERFAMILY SSF55729 1 140 5.83E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS08935 9389661a952b79bf38f31719fc833b15 148 Gene3D G3DSA:3.40.630.30 1 137 1.0E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS08935 9389661a952b79bf38f31719fc833b15 148 Pfam PF13673 Acetyltransferase (GNAT) domain 34 136 4.6E-16 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS00370 da38253d3a3aee03083fa9da1a05325d 464 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 5 318 25.955 T 06-07-2017 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 GTHT12_RS00370 da38253d3a3aee03083fa9da1a05325d 464 SUPERFAMILY SSF52402 8 238 7.84E-61 T 06-07-2017 GTHT12_RS00370 da38253d3a3aee03083fa9da1a05325d 464 Pfam PF01171 PP-loop family 21 204 1.2E-60 T 06-07-2017 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 GTHT12_RS00370 da38253d3a3aee03083fa9da1a05325d 464 Gene3D G3DSA:3.40.50.620 1 184 1.2E-18 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS00370 da38253d3a3aee03083fa9da1a05325d 464 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 384 430 6.0E-20 T 06-07-2017 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 GTHT12_RS00370 da38253d3a3aee03083fa9da1a05325d 464 Pfam PF09179 TilS substrate binding domain 256 324 6.6E-9 T 06-07-2017 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 GTHT12_RS00370 da38253d3a3aee03083fa9da1a05325d 464 SMART SM00977 384 457 4.2E-27 T 06-07-2017 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 GTHT12_RS00370 da38253d3a3aee03083fa9da1a05325d 464 Pfam PF11734 TilS substrate C-terminal domain 384 451 6.0E-18 T 06-07-2017 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 GTHT12_RS00370 da38253d3a3aee03083fa9da1a05325d 464 SUPERFAMILY SSF56037 335 457 4.45E-23 T 06-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 GTHT12_RS00370 da38253d3a3aee03083fa9da1a05325d 464 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 21 208 5.4E-62 T 06-07-2017 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 GTHT12_RS00370 da38253d3a3aee03083fa9da1a05325d 464 SUPERFAMILY SSF82829 215 323 3.92E-17 T 06-07-2017 GTHT12_RS13710 95d041e445390a7ea372c7c3bc835464 251 Pfam PF01478 Type IV leader peptidase family 106 208 1.6E-20 T 06-07-2017 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 GTHT12_RS13710 95d041e445390a7ea372c7c3bc835464 251 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 11 90 2.3E-27 T 06-07-2017 IPR010627 Peptidase A24A, N-terminal GTHT12_RS09970 aa47d5dd08a7b79c7bece3b52a71b788 310 SUPERFAMILY SSF161098 70 297 1.83E-50 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS09970 aa47d5dd08a7b79c7bece3b52a71b788 310 Gene3D G3DSA:1.10.3720.10 77 303 1.3E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS09970 aa47d5dd08a7b79c7bece3b52a71b788 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 299 2.6E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS16210 bf65fe4f8ea8399c9705c55749102dd5 82 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 2.0E-20 T 06-07-2017 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 GTHT12_RS16210 bf65fe4f8ea8399c9705c55749102dd5 82 Hamap MF_00167 Carbon storage regulator [csrA]. 1 70 21.712 T 06-07-2017 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 GTHT12_RS16210 bf65fe4f8ea8399c9705c55749102dd5 82 Pfam PF02599 Global regulator protein family 1 52 3.4E-27 T 06-07-2017 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 GTHT12_RS16210 bf65fe4f8ea8399c9705c55749102dd5 82 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 68 5.6E-32 T 06-07-2017 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 GTHT12_RS16210 bf65fe4f8ea8399c9705c55749102dd5 82 SUPERFAMILY SSF117130 1 55 6.8E-21 T 06-07-2017 GTHT12_RS03115 af135d93f09a8b9527da47253759ba17 334 SMART SM00382 49 233 2.5E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS03115 af135d93f09a8b9527da47253759ba17 334 Pfam PF00005 ABC transporter 41 184 1.7E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS03115 af135d93f09a8b9527da47253759ba17 334 SUPERFAMILY SSF52540 32 250 1.18E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03115 af135d93f09a8b9527da47253759ba17 334 Gene3D G3DSA:3.40.50.300 3 256 2.3E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS02095 8381ff70f4cdf23191062c3bbd2b7bbf 260 Pfam PF01381 Helix-turn-helix 9 61 5.6E-16 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GTHT12_RS02095 8381ff70f4cdf23191062c3bbd2b7bbf 260 SUPERFAMILY SSF47413 1 67 6.14E-20 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS02095 8381ff70f4cdf23191062c3bbd2b7bbf 260 Gene3D G3DSA:1.10.260.40 1 64 6.0E-28 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS02095 8381ff70f4cdf23191062c3bbd2b7bbf 260 SMART SM00530 6 61 9.3E-17 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GTHT12_RS03125 91cca8588e0a21ab76a2cbb25cc03fa5 261 Pfam PF06182 ABC-2 family transporter protein 33 260 1.4E-52 T 06-07-2017 IPR010390 Protein of unknown function DUF990 GTHT12_RS01950 98b2fd50d9fd448fbeb574dd8512f657 461 PRINTS PR00173 Glutamate-aspartate symporter signature 106 131 3.6E-19 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS01950 98b2fd50d9fd448fbeb574dd8512f657 461 PRINTS PR00173 Glutamate-aspartate symporter signature 182 204 3.6E-19 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS01950 98b2fd50d9fd448fbeb574dd8512f657 461 PRINTS PR00173 Glutamate-aspartate symporter signature 28 48 3.6E-19 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS01950 98b2fd50d9fd448fbeb574dd8512f657 461 PRINTS PR00173 Glutamate-aspartate symporter signature 397 417 3.6E-19 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS01950 98b2fd50d9fd448fbeb574dd8512f657 461 PRINTS PR00173 Glutamate-aspartate symporter signature 370 389 3.6E-19 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS01950 98b2fd50d9fd448fbeb574dd8512f657 461 PRINTS PR00173 Glutamate-aspartate symporter signature 76 96 3.6E-19 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS01950 98b2fd50d9fd448fbeb574dd8512f657 461 Pfam PF00375 Sodium:dicarboxylate symporter family 32 442 1.4E-98 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS01950 98b2fd50d9fd448fbeb574dd8512f657 461 SUPERFAMILY SSF118215 30 442 6.54E-92 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS01950 98b2fd50d9fd448fbeb574dd8512f657 461 Gene3D G3DSA:1.10.3860.10 22 448 1.9E-92 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 GTHT12_RS17695 ef7c3808398ea32f81aa9356ea58f25d 125 SUPERFAMILY SSF81442 8 120 1.26E-10 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS17695 ef7c3808398ea32f81aa9356ea58f25d 125 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 25 85 1.7E-6 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS10050 0fc79f05ccf2ca81860dd22d4b6731a7 276 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 19 265 9.2E-114 T 06-07-2017 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 GTHT12_RS10050 0fc79f05ccf2ca81860dd22d4b6731a7 276 PIRSF PIRSF036628 1 270 4.5E-112 T 06-07-2017 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 GTHT12_RS10050 0fc79f05ccf2ca81860dd22d4b6731a7 276 Hamap MF_01673 5-deoxy-glucuronate isomerase [iolB]. 1 267 57.548 T 06-07-2017 IPR023770 5-deoxy-glucuronate isomerase, Bacilli GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 GTHT12_RS10050 0fc79f05ccf2ca81860dd22d4b6731a7 276 Gene3D G3DSA:2.60.120.10 122 267 8.8E-74 T 06-07-2017 IPR014710 RmlC-like jelly roll fold GTHT12_RS10050 0fc79f05ccf2ca81860dd22d4b6731a7 276 SUPERFAMILY SSF51182 15 253 7.69E-72 T 06-07-2017 IPR011051 RmlC-like cupin domain GTHT12_RS10050 0fc79f05ccf2ca81860dd22d4b6731a7 276 Pfam PF04962 KduI/IolB family 10 264 1.8E-113 T 06-07-2017 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 GTHT12_RS10050 0fc79f05ccf2ca81860dd22d4b6731a7 276 Gene3D G3DSA:2.60.120.10 16 121 2.1E-44 T 06-07-2017 IPR014710 RmlC-like jelly roll fold GTHT12_RS04515 6a7c323d738b639b94db6a4a82c5d915 159 Pfam PF03862 SpoVA protein 32 149 1.2E-39 T 06-07-2017 IPR005562 SpoVA GTHT12_RS04515 6a7c323d738b639b94db6a4a82c5d915 159 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 14 152 1.8E-61 T 06-07-2017 IPR014203 Sporulation stage V, protein AC GTHT12_RS13210 18eb93e874c3f9c3a44963d37817f2ca 189 SMART SM00471 14 141 1.6E-11 T 06-07-2017 IPR003607 HD/PDEase domain GTHT12_RS13210 18eb93e874c3f9c3a44963d37817f2ca 189 TIGRFAM TIGR00277 HDIG: HDIG domain 16 109 7.5E-8 T 06-07-2017 IPR006675 HDIG domain GTHT12_RS13210 18eb93e874c3f9c3a44963d37817f2ca 189 SUPERFAMILY SSF109604 3 184 2.92E-39 T 06-07-2017 GTHT12_RS13210 18eb93e874c3f9c3a44963d37817f2ca 189 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 10 180 1.1E-67 T 06-07-2017 IPR005249 Conserved hypothetical protein CHP00488 GTHT12_RS13210 18eb93e874c3f9c3a44963d37817f2ca 189 Pfam PF01966 HD domain 18 130 4.2E-17 T 06-07-2017 IPR006674 HD domain GTHT12_RS13210 18eb93e874c3f9c3a44963d37817f2ca 189 Gene3D G3DSA:1.10.3210.10 1 185 3.7E-66 T 06-07-2017 IPR006674 HD domain GTHT12_RS06510 0f0c0ff2132424b2d36c8ff1736f275a 382 PIRSF PIRSF006205 1 382 2.5E-158 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 GTHT12_RS06510 0f0c0ff2132424b2d36c8ff1736f275a 382 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 143 226 2.1E-42 T 06-07-2017 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 GTHT12_RS06510 0f0c0ff2132424b2d36c8ff1736f275a 382 SUPERFAMILY SSF55347 123 261 1.01E-60 T 06-07-2017 GTHT12_RS06510 0f0c0ff2132424b2d36c8ff1736f275a 382 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 129 3.7E-42 T 06-07-2017 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 GTHT12_RS06510 0f0c0ff2132424b2d36c8ff1736f275a 382 SUPERFAMILY SSF69055 290 381 1.11E-29 T 06-07-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 GTHT12_RS06510 0f0c0ff2132424b2d36c8ff1736f275a 382 SUPERFAMILY SSF51735 2 147 1.01E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS06510 0f0c0ff2132424b2d36c8ff1736f275a 382 Pfam PF13288 DXP reductoisomerase C-terminal domain 258 375 4.4E-42 T 06-07-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 GTHT12_RS06510 0f0c0ff2132424b2d36c8ff1736f275a 382 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2 377 3.1E-164 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 GTHT12_RS06510 0f0c0ff2132424b2d36c8ff1736f275a 382 Gene3D G3DSA:1.10.1740.10 301 381 6.7E-30 T 06-07-2017 GTHT12_RS06510 0f0c0ff2132424b2d36c8ff1736f275a 382 Gene3D G3DSA:3.40.50.720 2 147 1.8E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS06510 0f0c0ff2132424b2d36c8ff1736f275a 382 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 380 47.636 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 GTHT12_RS08280 95c39abc62ba0ba079aaa6ec157060ca 49 Pfam PF11121 Protein of unknown function (DUF2639) 3 42 1.9E-18 T 06-07-2017 IPR022580 Protein of unknown function DUF2639 GTHT12_RS08280 95c39abc62ba0ba079aaa6ec157060ca 49 ProDom PD049467 YFLJ 3 40 0.005 T 06-07-2017 IPR022580 Protein of unknown function DUF2639 GTHT12_RS07850 829a253e4a10711ff4562411e1a24eda 295 SUPERFAMILY SSF52540 2 225 8.04E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07850 829a253e4a10711ff4562411e1a24eda 295 Gene3D G3DSA:3.40.50.300 1 224 1.1E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07850 829a253e4a10711ff4562411e1a24eda 295 Pfam PF00005 ABC transporter 19 156 5.8E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS07850 829a253e4a10711ff4562411e1a24eda 295 SMART SM00382 26 204 5.0E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS00360 1367b12ed8f36d0a3bfc5e4432a35e0c 246 Gene3D G3DSA:3.40.50.410 131 226 9.4E-8 T 06-07-2017 IPR002035 von Willebrand factor, type A GTHT12_RS00360 1367b12ed8f36d0a3bfc5e4432a35e0c 246 Pfam PF13519 von Willebrand factor type A domain 135 227 7.4E-7 T 06-07-2017 IPR002035 von Willebrand factor, type A GTHT12_RS00360 1367b12ed8f36d0a3bfc5e4432a35e0c 246 Pfam PF00092 von Willebrand factor type A domain 2 74 1.4E-6 T 06-07-2017 IPR002035 von Willebrand factor, type A GTHT12_RS00360 1367b12ed8f36d0a3bfc5e4432a35e0c 246 SUPERFAMILY SSF53300 133 225 5.64E-12 T 06-07-2017 IPR002035 von Willebrand factor, type A GTHT12_RS00360 1367b12ed8f36d0a3bfc5e4432a35e0c 246 Gene3D G3DSA:3.40.50.410 2 84 1.2E-7 T 06-07-2017 IPR002035 von Willebrand factor, type A GTHT12_RS00360 1367b12ed8f36d0a3bfc5e4432a35e0c 246 SUPERFAMILY SSF53300 2 78 2.38E-10 T 06-07-2017 IPR002035 von Willebrand factor, type A GTHT12_RS08160 d5e4be5cb187e5fdf8e7e8ab69a8da95 29 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 6 26 1.1E-7 T 06-07-2017 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM GTHT12_RS08160 d5e4be5cb187e5fdf8e7e8ab69a8da95 29 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 3 23 6.1E-7 T 06-07-2017 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM GTHT12_RS03915 a27be062cf4d9044e5efee3687cb63a0 511 SUPERFAMILY SSF51445 29 395 7.42E-113 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS03915 a27be062cf4d9044e5efee3687cb63a0 511 SUPERFAMILY SSF51011 395 475 1.13E-8 T 06-07-2017 GTHT12_RS03915 a27be062cf4d9044e5efee3687cb63a0 511 Gene3D G3DSA:2.60.40.1180 390 473 2.3E-10 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta GTHT12_RS03915 a27be062cf4d9044e5efee3687cb63a0 511 Pfam PF00128 Alpha amylase, catalytic domain 66 361 1.8E-79 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GTHT12_RS03915 a27be062cf4d9044e5efee3687cb63a0 511 Gene3D G3DSA:3.20.20.80 26 387 1.8E-112 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS03915 a27be062cf4d9044e5efee3687cb63a0 511 SMART SM00642 38 386 4.2E-103 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 GTHT12_RS03915 a27be062cf4d9044e5efee3687cb63a0 511 PIRSF PIRSF001024 2 463 7.9E-94 T 06-07-2017 GTHT12_RS06030 fc2f47d3a6f9989c7bf4e0d4b06cdd5f 207 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 207 30.038 T 06-07-2017 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 GTHT12_RS06030 fc2f47d3a6f9989c7bf4e0d4b06cdd5f 207 Gene3D G3DSA:3.40.50.2020 2 206 5.7E-59 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS06030 fc2f47d3a6f9989c7bf4e0d4b06cdd5f 207 Pfam PF00156 Phosphoribosyl transferase domain 44 172 4.2E-19 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 GTHT12_RS06030 fc2f47d3a6f9989c7bf4e0d4b06cdd5f 207 SUPERFAMILY SSF53271 8 206 1.06E-53 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS06030 fc2f47d3a6f9989c7bf4e0d4b06cdd5f 207 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 16 177 1.3E-48 T 06-07-2017 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 GTHT12_RS14460 e6501dc520d6b9be55c2ff6746ee7741 296 Pfam PF01609 Transposase DDE domain 120 292 1.4E-22 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 GTHT12_RS14460 e6501dc520d6b9be55c2ff6746ee7741 296 Pfam PF05598 Transposase domain (DUF772) 39 103 1.1E-10 T 06-07-2017 IPR008490 Transposase InsH, N-terminal GTHT12_RS00310 6c5f2cb5f37df40746c1e91cfdd2d086 518 Pfam PF01943 Polysaccharide biosynthesis protein 4 303 2.3E-34 T 06-07-2017 IPR002797 Polysaccharide biosynthesis protein GO:0016020 GTHT12_RS00310 6c5f2cb5f37df40746c1e91cfdd2d086 518 PIRSF PIRSF038958 1 513 1.7E-74 T 06-07-2017 IPR024923 Peptidoglycan biosynthesis protein, SpoVB type GTHT12_RS00310 6c5f2cb5f37df40746c1e91cfdd2d086 518 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 352 493 6.6E-25 T 06-07-2017 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain GTHT12_RS15790 940f7f24f90c83c1b30f0217749bc119 503 TIGRFAM TIGR02299 HpaE: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 8 491 1.4E-231 T 06-07-2017 IPR011985 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase GO:0018480|GO:1901023 GTHT12_RS15790 940f7f24f90c83c1b30f0217749bc119 503 Gene3D G3DSA:3.40.309.10 267 452 2.1E-72 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 GTHT12_RS15790 940f7f24f90c83c1b30f0217749bc119 503 Pfam PF00171 Aldehyde dehydrogenase family 15 477 1.5E-176 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS15790 940f7f24f90c83c1b30f0217749bc119 503 Gene3D G3DSA:3.40.605.10 8 266 1.7E-99 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS15790 940f7f24f90c83c1b30f0217749bc119 503 SUPERFAMILY SSF53720 6 480 1.44E-169 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GTHT12_RS15790 940f7f24f90c83c1b30f0217749bc119 503 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 GTHT12_RS15790 940f7f24f90c83c1b30f0217749bc119 503 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 GTHT12_RS11000 7cfee50d0b32b752e17f63247265e5d7 209 Pfam PF13171 Protein of unknown function (DUF4004) 4 199 1.5E-82 T 06-07-2017 IPR025063 Protein of unknown function DUF4004 GTHT12_RS12930 bc809784c7ef458b703027337a1ac1fb 374 Gene3D G3DSA:3.20.20.70 31 145 1.3E-6 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS12930 bc809784c7ef458b703027337a1ac1fb 374 Gene3D G3DSA:3.30.413.10 264 325 8.8E-4 T 06-07-2017 GTHT12_RS12930 bc809784c7ef458b703027337a1ac1fb 374 Pfam PF04551 GcpE protein 10 351 2.5E-144 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 GTHT12_RS12930 bc809784c7ef458b703027337a1ac1fb 374 SUPERFAMILY SSF56014 263 355 2.04E-15 T 06-07-2017 GTHT12_RS12930 bc809784c7ef458b703027337a1ac1fb 374 PIRSF PIRSF004640 1 361 2.2E-158 T 06-07-2017 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 GTHT12_RS12930 bc809784c7ef458b703027337a1ac1fb 374 SUPERFAMILY SSF51717 16 212 2.2E-16 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 GTHT12_RS12930 bc809784c7ef458b703027337a1ac1fb 374 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 7 350 1.2E-136 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 GTHT12_RS12930 bc809784c7ef458b703027337a1ac1fb 374 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 5 355 36.04 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 GTHT12_RS15700 1e1fc933821e8a705a25215c7ed65e44 362 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 10 358 3.8E-51 T 06-07-2017 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 GTHT12_RS15700 1e1fc933821e8a705a25215c7ed65e44 362 Pfam PF03845 Spore germination protein 9 324 2.4E-86 T 06-07-2017 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 GTHT12_RS00660 1ae372312ae958305a3ce47078781a85 211 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 06-07-2017 IPR019926 Ribosomal protein L3, conserved site GTHT12_RS00660 1ae372312ae958305a3ce47078781a85 211 Gene3D G3DSA:4.10.960.10 77 156 1.6E-34 T 06-07-2017 GTHT12_RS00660 1ae372312ae958305a3ce47078781a85 211 Pfam PF00297 Ribosomal protein L3 99 180 2.1E-17 T 06-07-2017 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00660 1ae372312ae958305a3ce47078781a85 211 Gene3D G3DSA:2.40.30.10 157 209 8.2E-15 T 06-07-2017 GTHT12_RS00660 1ae372312ae958305a3ce47078781a85 211 Gene3D G3DSA:2.40.30.10 4 33 8.2E-15 T 06-07-2017 GTHT12_RS00660 1ae372312ae958305a3ce47078781a85 211 SUPERFAMILY SSF50447 1 210 1.59E-83 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain GTHT12_RS00660 1ae372312ae958305a3ce47078781a85 211 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 203 2.2E-87 T 06-07-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00660 1ae372312ae958305a3ce47078781a85 211 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 206 39.678 T 06-07-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS11375 c76f21b781d291a1cbf0acc0a4f09d3a 147 Pfam PF00011 Hsp20/alpha crystallin family 44 144 5.3E-23 T 06-07-2017 IPR002068 Alpha crystallin/Hsp20 domain GTHT12_RS11375 c76f21b781d291a1cbf0acc0a4f09d3a 147 Gene3D G3DSA:2.60.40.790 2 146 7.0E-45 T 06-07-2017 IPR008978 HSP20-like chaperone GTHT12_RS11375 c76f21b781d291a1cbf0acc0a4f09d3a 147 SUPERFAMILY SSF49764 16 145 1.05E-38 T 06-07-2017 IPR008978 HSP20-like chaperone GTHT12_RS15715 c16140163d5af7a01d3b1f3ce26acbed 80 Pfam PF00202 Aminotransferase class-III 1 64 2.1E-5 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GTHT12_RS15715 c16140163d5af7a01d3b1f3ce26acbed 80 SUPERFAMILY SSF53383 1 68 6.68E-7 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS15715 c16140163d5af7a01d3b1f3ce26acbed 80 Gene3D G3DSA:3.90.1150.10 1 69 1.3E-8 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS06900 b201040d67036af0e74866412d2fce3d 145 Pfam PF10747 Protein of unknown function (DUF2522) 4 136 3.1E-31 T 06-07-2017 IPR019683 Sporulation inhibitor of replication protein SirA GTHT12_RS10665 37b4ee7336e7b93e4a765cbf490a29eb 495 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 6 302 2.7E-16 T 06-07-2017 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 GTHT12_RS10665 37b4ee7336e7b93e4a765cbf490a29eb 495 SUPERFAMILY SSF53649 2 353 1.41E-42 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 GTHT12_RS10665 37b4ee7336e7b93e4a765cbf490a29eb 495 SUPERFAMILY SSF53649 408 483 1.41E-42 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 GTHT12_RS10665 37b4ee7336e7b93e4a765cbf490a29eb 495 Gene3D G3DSA:3.40.720.10 2 328 4.6E-28 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 GTHT12_RS00640 673f3b3a71edd9fc5578dd92fa623e4e 156 SUPERFAMILY SSF47973 1 149 4.97E-66 T 06-07-2017 IPR023798 Ribosomal protein S7 domain GTHT12_RS00640 673f3b3a71edd9fc5578dd92fa623e4e 156 PIRSF PIRSF002122 6 156 5.3E-63 T 06-07-2017 IPR000235 Ribosomal protein S5/S7 GO:0006412 GTHT12_RS00640 673f3b3a71edd9fc5578dd92fa623e4e 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 06-07-2017 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00640 673f3b3a71edd9fc5578dd92fa623e4e 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.3E-72 T 06-07-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 GTHT12_RS00640 673f3b3a71edd9fc5578dd92fa623e4e 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 36.978 T 06-07-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 GTHT12_RS00640 673f3b3a71edd9fc5578dd92fa623e4e 156 Gene3D G3DSA:1.10.455.10 8 156 1.1E-70 T 06-07-2017 IPR023798 Ribosomal protein S7 domain GTHT12_RS00640 673f3b3a71edd9fc5578dd92fa623e4e 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 9.8E-71 T 06-07-2017 IPR023798 Ribosomal protein S7 domain GTHT12_RS11770 3fbcd103b8c2a62b32f8279da8b3d9b6 396 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 11 382 7.6E-88 T 06-07-2017 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 GTHT12_RS11770 3fbcd103b8c2a62b32f8279da8b3d9b6 396 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 218 381 2.4E-33 T 06-07-2017 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 GTHT12_RS16105 d256261baeef9cfede245322a1c66e7f 287 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 18 221 1.1E-67 T 06-07-2017 IPR003740 Uncharacterised membrane protein YitT GTHT12_RS16105 d256261baeef9cfede245322a1c66e7f 287 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 227 281 1.4E-21 T 06-07-2017 IPR019264 Domain of unknown function DUF2179 GTHT12_RS16105 d256261baeef9cfede245322a1c66e7f 287 PIRSF PIRSF006483 1 287 1.8E-91 T 06-07-2017 IPR003740 Uncharacterised membrane protein YitT GTHT12_RS12105 3f251d758080ab61dc0109bea9065f6c 397 PIRSF PIRSF001259 1 397 1.1E-191 T 06-07-2017 GTHT12_RS12105 3f251d758080ab61dc0109bea9065f6c 397 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 201 38.54 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GTHT12_RS12105 3f251d758080ab61dc0109bea9065f6c 397 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 6 196 9.9E-86 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GTHT12_RS12105 3f251d758080ab61dc0109bea9065f6c 397 SUPERFAMILY SSF142695 202 374 2.48E-76 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 GTHT12_RS12105 3f251d758080ab61dc0109bea9065f6c 397 Gene3D G3DSA:3.90.870.10 2 209 9.7E-98 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain GTHT12_RS12105 3f251d758080ab61dc0109bea9065f6c 397 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 207 395 2.2E-81 T 06-07-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 GTHT12_RS12105 3f251d758080ab61dc0109bea9065f6c 397 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 202 397 42.946 T 06-07-2017 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 GTHT12_RS12105 3f251d758080ab61dc0109bea9065f6c 397 Pfam PF00925 GTP cyclohydrolase II 206 371 3.8E-78 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 GTHT12_RS12105 3f251d758080ab61dc0109bea9065f6c 397 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 1 393 56.695 T 06-07-2017 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 GTHT12_RS12105 3f251d758080ab61dc0109bea9065f6c 397 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 1 197 6.2E-79 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 GTHT12_RS12105 3f251d758080ab61dc0109bea9065f6c 397 SUPERFAMILY SSF55821 2 204 5.49E-85 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain GTHT12_RS13900 8d900cc712993fea2435e21264b7c407 299 Gene3D G3DSA:3.20.10.10 125 283 1.6E-54 T 06-07-2017 GTHT12_RS13900 8d900cc712993fea2435e21264b7c407 299 Gene3D G3DSA:3.30.470.10 5 120 1.3E-45 T 06-07-2017 GTHT12_RS13900 8d900cc712993fea2435e21264b7c407 299 ProSitePatterns PS00770 Aminotransferases class-IV signature. 185 214 - T 06-07-2017 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 GTHT12_RS13900 8d900cc712993fea2435e21264b7c407 299 SUPERFAMILY SSF56752 3 282 8.5E-95 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 GTHT12_RS13900 8d900cc712993fea2435e21264b7c407 299 Pfam PF01063 Amino-transferase class IV 32 258 1.3E-56 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 GTHT12_RS13900 8d900cc712993fea2435e21264b7c407 299 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 7 285 8.5E-105 T 06-07-2017 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108 GTHT12_RS09055 0a6de1a299bdb8c016619e3fe0c80394 288 Pfam PF03773 Predicted permease 9 285 6.1E-50 T 06-07-2017 IPR005524 Predicted permease DUF318 GTHT12_RS10190 18e554f31875ae070f9834e4d22ec216 441 SUPERFAMILY SSF51126 29 440 1.21E-81 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor GTHT12_RS10190 18e554f31875ae070f9834e4d22ec216 441 Pfam PF00544 Pectate lyase 142 355 5.2E-53 T 06-07-2017 IPR002022 Pectate lyase/Amb allergen GTHT12_RS10190 18e554f31875ae070f9834e4d22ec216 441 Gene3D G3DSA:2.160.20.10 31 440 4.6E-125 T 06-07-2017 IPR012334 Pectin lyase fold GTHT12_RS10190 18e554f31875ae070f9834e4d22ec216 441 SMART SM00656 131 361 3.1E-52 T 06-07-2017 IPR002022 Pectate lyase/Amb allergen GTHT12_RS10805 ec53cc4f758bfb7cb42d2268ce03f741 374 SUPERFAMILY SSF88697 277 366 6.63E-20 T 06-07-2017 IPR015947 PUA-like domain GTHT12_RS10805 ec53cc4f758bfb7cb42d2268ce03f741 374 Gene3D G3DSA:3.40.1160.10 4 254 1.2E-54 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase GTHT12_RS10805 ec53cc4f758bfb7cb42d2268ce03f741 374 Hamap MF_00456 Glutamate 5-kinase [proB]. 4 261 35.61 T 06-07-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 GTHT12_RS10805 ec53cc4f758bfb7cb42d2268ce03f741 374 Gene3D G3DSA:2.30.130.10 275 365 1.0E-25 T 06-07-2017 IPR015947 PUA-like domain GTHT12_RS10805 ec53cc4f758bfb7cb42d2268ce03f741 374 Pfam PF01472 PUA domain 277 349 2.3E-20 T 06-07-2017 IPR002478 PUA domain GO:0003723 GTHT12_RS10805 ec53cc4f758bfb7cb42d2268ce03f741 374 PRINTS PR00474 Glutamate 5-kinase family signature 147 174 6.7E-53 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 GTHT12_RS10805 ec53cc4f758bfb7cb42d2268ce03f741 374 PRINTS PR00474 Glutamate 5-kinase family signature 41 55 6.7E-53 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 GTHT12_RS10805 ec53cc4f758bfb7cb42d2268ce03f741 374 PRINTS PR00474 Glutamate 5-kinase family signature 115 136 6.7E-53 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 GTHT12_RS10805 ec53cc4f758bfb7cb42d2268ce03f741 374 PRINTS PR00474 Glutamate 5-kinase family signature 208 228 6.7E-53 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 GTHT12_RS10805 ec53cc4f758bfb7cb42d2268ce03f741 374 PRINTS PR00474 Glutamate 5-kinase family signature 75 103 6.7E-53 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 GTHT12_RS10805 ec53cc4f758bfb7cb42d2268ce03f741 374 Pfam PF00696 Amino acid kinase family 4 232 5.4E-43 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase GTHT12_RS10805 ec53cc4f758bfb7cb42d2268ce03f741 374 ProSitePatterns PS00902 Glutamate 5-kinase signature. 206 223 - T 06-07-2017 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 GTHT12_RS10805 ec53cc4f758bfb7cb42d2268ce03f741 374 SMART SM00359 277 359 3.9E-15 T 06-07-2017 IPR002478 PUA domain GO:0003723 GTHT12_RS10805 ec53cc4f758bfb7cb42d2268ce03f741 374 TIGRFAM TIGR01027 proB: glutamate 5-kinase 4 365 3.3E-137 T 06-07-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 GTHT12_RS10805 ec53cc4f758bfb7cb42d2268ce03f741 374 SUPERFAMILY SSF53633 4 254 1.15E-67 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase GTHT12_RS10805 ec53cc4f758bfb7cb42d2268ce03f741 374 PIRSF PIRSF000729 1 368 1.3E-133 T 06-07-2017 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 GTHT12_RS18190 af663ecfd78553fc030822c0aa50df5e 207 SUPERFAMILY SSF53163 13 197 5.49E-52 T 06-07-2017 IPR023430 Peptidase HybD-like domain GTHT12_RS18190 af663ecfd78553fc030822c0aa50df5e 207 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 43 181 6.7E-65 T 06-07-2017 IPR009665 Protein of unknown function DUF1256 GTHT12_RS18190 af663ecfd78553fc030822c0aa50df5e 207 Pfam PF06866 Protein of unknown function (DUF1256) 24 180 9.1E-62 T 06-07-2017 IPR009665 Protein of unknown function DUF1256 GTHT12_RS14825 245b961e2d91583ec81dfcc51246edf0 131 Pfam PF05105 Bacteriophage holin family 17 128 7.3E-37 T 06-07-2017 IPR006480 Bacteriophage holin family GTHT12_RS14825 245b961e2d91583ec81dfcc51246edf0 131 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 13 129 1.5E-28 T 06-07-2017 IPR006480 Bacteriophage holin family GTHT12_RS06375 e0ac26fbd4609300f6304a642dfbea83 74 Pfam PF06289 Flagellar protein (FlbD) 1 58 1.7E-26 T 06-07-2017 IPR009384 Flagellar GTHT12_RS00805 2b5ce0d825e81cbb5ae05a751c21fd90 279 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 7 273 2.3E-118 T 06-07-2017 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 GTHT12_RS00805 2b5ce0d825e81cbb5ae05a751c21fd90 279 Pfam PF00005 ABC transporter 24 169 2.9E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS00805 2b5ce0d825e81cbb5ae05a751c21fd90 279 Gene3D G3DSA:3.40.50.300 2 230 1.1E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00805 2b5ce0d825e81cbb5ae05a751c21fd90 279 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS00805 2b5ce0d825e81cbb5ae05a751c21fd90 279 SUPERFAMILY SSF52540 4 229 7.48E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00805 2b5ce0d825e81cbb5ae05a751c21fd90 279 SMART SM00382 32 217 3.4E-20 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS08070 2b0333ac3be2053ef2e067aff7f1ccc6 96 SUPERFAMILY SSF89360 1 95 1.44E-12 T 06-07-2017 IPR000361 FeS cluster biogenesis GTHT12_RS08070 2b0333ac3be2053ef2e067aff7f1ccc6 96 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 87 1.1E-8 T 06-07-2017 IPR000361 FeS cluster biogenesis GTHT12_RS08070 2b0333ac3be2053ef2e067aff7f1ccc6 96 Gene3D G3DSA:2.60.300.12 2 84 4.3E-4 T 06-07-2017 IPR000361 FeS cluster biogenesis GTHT12_RS08070 2b0333ac3be2053ef2e067aff7f1ccc6 96 PIRSF PIRSF034852 1 96 1.7E-39 T 06-07-2017 IPR008326 Uncharacterised conserved protein UCP034852 GTHT12_RS00965 a1822c55e5f2a2bf82584622370ee0e5 552 Gene3D G3DSA:1.20.1560.10 6 309 3.0E-51 T 06-07-2017 GTHT12_RS00965 a1822c55e5f2a2bf82584622370ee0e5 552 SUPERFAMILY SSF90123 4 309 7.06E-52 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GTHT12_RS00965 a1822c55e5f2a2bf82584622370ee0e5 552 SUPERFAMILY SSF52540 330 542 9.46E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00965 a1822c55e5f2a2bf82584622370ee0e5 552 Pfam PF00005 ABC transporter 348 495 4.0E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS00965 a1822c55e5f2a2bf82584622370ee0e5 552 SMART SM00382 357 541 5.4E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS00965 a1822c55e5f2a2bf82584622370ee0e5 552 Gene3D G3DSA:3.40.50.300 331 541 8.8E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00965 a1822c55e5f2a2bf82584622370ee0e5 552 Pfam PF00664 ABC transporter transmembrane region 16 284 1.7E-31 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GTHT12_RS02865 ecbd5ddaa72d9346746cd261a0559672 399 SUPERFAMILY SSF56645 2 243 4.45E-97 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 GTHT12_RS02865 ecbd5ddaa72d9346746cd261a0559672 399 Gene3D G3DSA:1.10.540.10 1 121 1.8E-45 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS02865 ecbd5ddaa72d9346746cd261a0559672 399 Gene3D G3DSA:2.40.110.10 122 223 1.7E-44 T 06-07-2017 GTHT12_RS02865 ecbd5ddaa72d9346746cd261a0559672 399 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 GTHT12_RS02865 ecbd5ddaa72d9346746cd261a0559672 399 SUPERFAMILY SSF47203 228 387 1.29E-52 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS02865 ecbd5ddaa72d9346746cd261a0559672 399 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 376 7.7E-45 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 GTHT12_RS02865 ecbd5ddaa72d9346746cd261a0559672 399 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 119 3.8E-41 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 GTHT12_RS02865 ecbd5ddaa72d9346746cd261a0559672 399 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 218 6.5E-31 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 GTHT12_RS02865 ecbd5ddaa72d9346746cd261a0559672 399 Gene3D G3DSA:1.20.140.10 224 384 1.3E-64 T 06-07-2017 GTHT12_RS07380 3c0f7b3125aacf42f438bc4330f84897 538 Pfam PF07905 Purine catabolism regulatory protein-like family 11 130 3.8E-36 T 06-07-2017 IPR012914 Purine catabolism PurC-like domain GTHT12_RS07380 3c0f7b3125aacf42f438bc4330f84897 538 Gene3D G3DSA:1.10.10.60 464 497 8.0E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS07380 3c0f7b3125aacf42f438bc4330f84897 538 Pfam PF13556 PucR C-terminal helix-turn-helix domain 461 519 2.3E-16 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain GTHT12_RS08445 4bee4d6726885edf8d70d7ccd80da7b6 215 Gene3D G3DSA:3.20.20.70 1 205 7.6E-61 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS08445 4bee4d6726885edf8d70d7ccd80da7b6 215 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 2 200 8.2E-24 T 06-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 GTHT12_RS08445 4bee4d6726885edf8d70d7ccd80da7b6 215 SUPERFAMILY SSF51366 2 207 2.83E-36 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 GTHT12_RS08445 4bee4d6726885edf8d70d7ccd80da7b6 215 SMART SM00934 2 201 1.9E-38 T 06-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 GTHT12_RS02210 dbda2048d650c740c94d2bce4c959cf5 347 SUPERFAMILY SSF51161 199 322 6.94E-20 T 06-07-2017 IPR011004 Trimeric LpxA-like GTHT12_RS02210 dbda2048d650c740c94d2bce4c959cf5 347 Gene3D G3DSA:2.160.10.10 246 323 8.6E-15 T 06-07-2017 GTHT12_RS02210 dbda2048d650c740c94d2bce4c959cf5 347 Pfam PF00483 Nucleotidyl transferase 2 229 3.5E-48 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 GTHT12_RS02210 dbda2048d650c740c94d2bce4c959cf5 347 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 248 282 4.5E-7 T 06-07-2017 IPR001451 Hexapeptide repeat GTHT12_RS02210 dbda2048d650c740c94d2bce4c959cf5 347 Gene3D G3DSA:3.90.550.10 1 234 6.2E-69 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS02210 dbda2048d650c740c94d2bce4c959cf5 347 SUPERFAMILY SSF53448 1 235 1.13E-77 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS15040 9562125d66959f26d48d51001629fdb7 68 SUPERFAMILY SSF54593 3 67 7.25E-14 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GTHT12_RS15040 9562125d66959f26d48d51001629fdb7 68 Gene3D G3DSA:3.10.180.10 3 64 1.9E-15 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GTHT12_RS15040 9562125d66959f26d48d51001629fdb7 68 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 51 1.7E-7 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain GTHT12_RS14695 a2fd0433e4c399479e3f342e773b44db 398 Gene3D G3DSA:1.20.1250.20 17 189 1.9E-24 T 06-07-2017 GTHT12_RS14695 a2fd0433e4c399479e3f342e773b44db 398 Gene3D G3DSA:1.20.1250.20 202 390 1.6E-26 T 06-07-2017 GTHT12_RS14695 a2fd0433e4c399479e3f342e773b44db 398 SUPERFAMILY SSF103473 18 389 2.49E-49 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS14695 a2fd0433e4c399479e3f342e773b44db 398 Pfam PF12832 MFS_1 like family 18 360 8.9E-46 T 06-07-2017 IPR024989 Major facilitator superfamily associated domain GTHT12_RS13920 6d5fb2d590ff895916fabd5078755060 358 SMART SM00909 97 188 1.2E-25 T 06-07-2017 IPR019606 GerMN domain GTHT12_RS13920 6d5fb2d590ff895916fabd5078755060 358 SMART SM00909 249 338 6.6E-21 T 06-07-2017 IPR019606 GerMN domain GTHT12_RS13920 6d5fb2d590ff895916fabd5078755060 358 Pfam PF10646 Sporulation and spore germination 221 332 7.8E-17 T 06-07-2017 IPR019606 GerMN domain GTHT12_RS13920 6d5fb2d590ff895916fabd5078755060 358 Pfam PF10646 Sporulation and spore germination 74 182 8.2E-20 T 06-07-2017 IPR019606 GerMN domain GTHT12_RS13815 67e2b20cdeeae0bcaacada9a857507eb 271 Pfam PF01578 Cytochrome C assembly protein 64 265 6.6E-28 T 06-07-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 GTHT12_RS06340 00deadd106ea6ff6ecd12cff68511924 259 TIGRFAM TIGR03825 FliH_bacil: flagellar assembly protein FliH 4 253 2.3E-107 T 06-07-2017 IPR022524 Flagellar assembly FliH, Bacilli GTHT12_RS06340 00deadd106ea6ff6ecd12cff68511924 259 Pfam PF02108 Flagellar assembly protein FliH 124 239 3.3E-16 T 06-07-2017 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE GTHT12_RS14135 45fbd2c1575799ad2b39904f2ea87c52 83 Pfam PF06961 Protein of unknown function (DUF1294) 9 63 6.8E-24 T 06-07-2017 IPR010718 Protein of unknown function DUF1294 GTHT12_RS13365 3eb2d6f1cfb9909a7f33716d9ad0ccc3 98 Hamap MF_01448 UPF0473 protein . 4 92 21.507 T 06-07-2017 IPR009711 Uncharacterised protein family UPF0473 GTHT12_RS13365 3eb2d6f1cfb9909a7f33716d9ad0ccc3 98 Pfam PF06949 Protein of unknown function (DUF1292) 13 90 1.7E-18 T 06-07-2017 IPR009711 Uncharacterised protein family UPF0473 GTHT12_RS14420 67d3726ad240544d59609efcbec12916 381 Gene3D G3DSA:3.90.1150.10 247 371 2.1E-34 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS14420 67d3726ad240544d59609efcbec12916 381 Pfam PF00266 Aminotransferase class-V 2 362 8.2E-81 T 06-07-2017 IPR000192 Aminotransferase class V domain GTHT12_RS14420 67d3726ad240544d59609efcbec12916 381 SUPERFAMILY SSF53383 1 374 4.52E-109 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS14420 67d3726ad240544d59609efcbec12916 381 PIRSF PIRSF005572 1 379 1.3E-121 T 06-07-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 GTHT12_RS14420 67d3726ad240544d59609efcbec12916 381 Gene3D G3DSA:3.40.640.10 14 246 6.0E-88 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS16540 cab9d5fc3474b6dc011d3172f002cafe 478 SUPERFAMILY SSF51445 5 471 8.78E-177 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS16540 cab9d5fc3474b6dc011d3172f002cafe 478 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 374 382 - T 06-07-2017 IPR018120 Glycoside hydrolase family 1, active site GTHT12_RS16540 cab9d5fc3474b6dc011d3172f002cafe 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 292 306 3.1E-19 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 GTHT12_RS16540 cab9d5fc3474b6dc011d3172f002cafe 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 374 382 3.1E-19 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 GTHT12_RS16540 cab9d5fc3474b6dc011d3172f002cafe 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 395 406 3.1E-19 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 GTHT12_RS16540 cab9d5fc3474b6dc011d3172f002cafe 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 416 433 3.1E-19 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 GTHT12_RS16540 cab9d5fc3474b6dc011d3172f002cafe 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 440 452 3.1E-19 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 GTHT12_RS16540 cab9d5fc3474b6dc011d3172f002cafe 478 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 13 27 - T 06-07-2017 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site GTHT12_RS16540 cab9d5fc3474b6dc011d3172f002cafe 478 Gene3D G3DSA:3.20.20.80 8 476 3.1E-172 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS16540 cab9d5fc3474b6dc011d3172f002cafe 478 Pfam PF00232 Glycosyl hydrolase family 1 7 475 7.6E-183 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 GTHT12_RS08380 704355f6aaeafc0cde5d703c4317bb9e 578 SUPERFAMILY SSF90123 2 315 3.53E-67 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GTHT12_RS08380 704355f6aaeafc0cde5d703c4317bb9e 578 Pfam PF00664 ABC transporter transmembrane region 26 280 5.6E-35 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 GTHT12_RS08380 704355f6aaeafc0cde5d703c4317bb9e 578 SUPERFAMILY SSF52540 326 566 5.89E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08380 704355f6aaeafc0cde5d703c4317bb9e 578 SMART SM00382 358 542 8.5E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS08380 704355f6aaeafc0cde5d703c4317bb9e 578 Gene3D G3DSA:1.20.1560.10 2 315 4.9E-59 T 06-07-2017 GTHT12_RS08380 704355f6aaeafc0cde5d703c4317bb9e 578 Pfam PF00005 ABC transporter 349 498 1.8E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS08380 704355f6aaeafc0cde5d703c4317bb9e 578 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS08380 704355f6aaeafc0cde5d703c4317bb9e 578 Gene3D G3DSA:3.40.50.300 332 560 4.7E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17440 8d0cdbe20a8f9a1ed828141c168b0db0 139 Gene3D G3DSA:3.30.70.20 14 107 7.5E-19 T 06-07-2017 GTHT12_RS17440 8d0cdbe20a8f9a1ed828141c168b0db0 139 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 88 99 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GTHT12_RS17440 8d0cdbe20a8f9a1ed828141c168b0db0 139 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 7 121 2.6E-34 T 06-07-2017 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17440 8d0cdbe20a8f9a1ed828141c168b0db0 139 SUPERFAMILY SSF54862 24 126 6.28E-25 T 06-07-2017 GTHT12_RS17440 8d0cdbe20a8f9a1ed828141c168b0db0 139 Pfam PF12838 4Fe-4S dicluster domain 45 102 3.1E-10 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain GTHT12_RS17440 8d0cdbe20a8f9a1ed828141c168b0db0 139 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 46 57 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GTHT12_RS03700 8415eac554d9d5f72e4d6c39fd4c78f6 190 SUPERFAMILY SSF48498 78 189 6.4E-14 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal GTHT12_RS03700 8415eac554d9d5f72e4d6c39fd4c78f6 190 SUPERFAMILY SSF46689 3 77 1.16E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS03700 8415eac554d9d5f72e4d6c39fd4c78f6 190 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 52 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site GTHT12_RS03700 8415eac554d9d5f72e4d6c39fd4c78f6 190 Gene3D G3DSA:1.10.10.60 3 54 6.3E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS03700 8415eac554d9d5f72e4d6c39fd4c78f6 190 Gene3D G3DSA:1.10.357.10 55 189 3.9E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 GTHT12_RS03700 8415eac554d9d5f72e4d6c39fd4c78f6 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 1.3E-17 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS03700 8415eac554d9d5f72e4d6c39fd4c78f6 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 4.7E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS03700 8415eac554d9d5f72e4d6c39fd4c78f6 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 4.7E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS15570 d00a0d42e99ce7fda0dc17eced5e8620 282 Gene3D G3DSA:3.20.20.410 1 281 4.0E-96 T 06-07-2017 IPR002763 Protein of unknown function DUF72 GTHT12_RS15570 d00a0d42e99ce7fda0dc17eced5e8620 282 SUPERFAMILY SSF117396 1 269 2.35E-84 T 06-07-2017 IPR002763 Protein of unknown function DUF72 GTHT12_RS15570 d00a0d42e99ce7fda0dc17eced5e8620 282 Pfam PF01904 Protein of unknown function DUF72 16 265 2.0E-64 T 06-07-2017 IPR002763 Protein of unknown function DUF72 GTHT12_RS09570 2013d52e57deb0b50af8324536c2164f 191 Pfam PF02613 Nitrate reductase delta subunit 41 162 1.4E-7 T 06-07-2017 IPR020945 DMSO/Nitrate reductase chaperone GTHT12_RS09570 2013d52e57deb0b50af8324536c2164f 191 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 14 165 1.0E-41 T 06-07-2017 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 GTHT12_RS09570 2013d52e57deb0b50af8324536c2164f 191 SUPERFAMILY SSF89155 6 168 7.98E-27 T 06-07-2017 IPR020945 DMSO/Nitrate reductase chaperone GTHT12_RS09570 2013d52e57deb0b50af8324536c2164f 191 Gene3D G3DSA:1.10.3480.10 4 25 2.6E-4 T 06-07-2017 IPR020945 DMSO/Nitrate reductase chaperone GTHT12_RS09570 2013d52e57deb0b50af8324536c2164f 191 Gene3D G3DSA:1.10.3480.10 57 127 2.6E-4 T 06-07-2017 IPR020945 DMSO/Nitrate reductase chaperone GTHT12_RS00585 8bb30bb16dfeab47c44c549051bce059 60 Gene3D G3DSA:1.20.5.1030 1 59 4.5E-24 T 06-07-2017 GTHT12_RS00585 8bb30bb16dfeab47c44c549051bce059 60 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 5 59 5.1E-24 T 06-07-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 GTHT12_RS00585 8bb30bb16dfeab47c44c549051bce059 60 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 6 57 1.1E-22 T 06-07-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 GTHT12_RS00585 8bb30bb16dfeab47c44c549051bce059 60 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 7 35 - T 06-07-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 GTHT12_RS00585 8bb30bb16dfeab47c44c549051bce059 60 Hamap MF_00422 Protein translocase subunit SecE [secE]. 2 57 13.789 T 06-07-2017 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 GTHT12_RS18505 1dcd5c35d80d949e54e3084df0b30602 304 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 2 84 1.6E-13 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 GTHT12_RS18505 1dcd5c35d80d949e54e3084df0b30602 304 Gene3D G3DSA:1.10.150.130 2 94 1.8E-19 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal GTHT12_RS18505 1dcd5c35d80d949e54e3084df0b30602 304 Pfam PF00589 Phage integrase family 110 290 4.5E-30 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS18505 1dcd5c35d80d949e54e3084df0b30602 304 SUPERFAMILY SSF56349 2 298 2.65E-50 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 GTHT12_RS18505 1dcd5c35d80d949e54e3084df0b30602 304 Gene3D G3DSA:1.10.443.10 107 302 2.0E-39 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS03375 d0453f987398a299119d376bc262b24d 158 Pfam PF00085 Thioredoxin 60 150 1.4E-11 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 GTHT12_RS03375 d0453f987398a299119d376bc262b24d 158 SUPERFAMILY SSF52833 46 150 8.96E-25 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS03375 d0453f987398a299119d376bc262b24d 158 Gene3D G3DSA:3.40.30.10 48 150 7.5E-23 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS18240 04b5c2a7c4caa7e75e9d00240f8f946f 121 Pfam PF00825 Ribonuclease P 1 108 3.0E-34 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 GTHT12_RS18240 04b5c2a7c4caa7e75e9d00240f8f946f 121 SUPERFAMILY SSF54211 1 111 3.03E-34 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS18240 04b5c2a7c4caa7e75e9d00240f8f946f 121 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 7 101 2.0E-46 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 GTHT12_RS18240 04b5c2a7c4caa7e75e9d00240f8f946f 121 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 111 19.781 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 GTHT12_RS18240 04b5c2a7c4caa7e75e9d00240f8f946f 121 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 1 109 1.2E-30 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 GTHT12_RS18240 04b5c2a7c4caa7e75e9d00240f8f946f 121 Gene3D G3DSA:3.30.230.10 1 113 6.1E-39 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GTHT12_RS18240 04b5c2a7c4caa7e75e9d00240f8f946f 121 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 51 65 - T 06-07-2017 IPR020539 Ribonuclease P, conserved site GO:0004526 GTHT12_RS17560 abccf10e1b9f5015415c9d6ba27f92f5 301 TIGRFAM TIGR02837 spore_II_R: stage II sporulation protein R 6 170 2.8E-60 T 06-07-2017 IPR014202 Sporulation stage II, protein R GTHT12_RS17560 abccf10e1b9f5015415c9d6ba27f92f5 301 Pfam PF09551 Stage II sporulation protein R (spore_II_R) 40 165 1.4E-47 T 06-07-2017 IPR014202 Sporulation stage II, protein R GTHT12_RS08080 5592a7ffde3f446c9938e5645d6f2599 197 Pfam PF04367 Protein of unknown function (DUF502) 56 157 3.1E-25 T 06-07-2017 IPR007462 Protein of unknown function DUF502 GTHT12_RS16065 453ce35bb451dea1965316e24a66a7ae 390 Gene3D G3DSA:2.30.42.10 297 371 3.6E-12 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS16065 453ce35bb451dea1965316e24a66a7ae 390 SMART SM00228 276 355 2.0E-5 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS16065 453ce35bb451dea1965316e24a66a7ae 390 SUPERFAMILY SSF50156 297 380 3.68E-13 T 06-07-2017 IPR001478 PDZ domain GO:0005515 GTHT12_RS03750 a0fa7d5c2ef5d06504469db1027aa6fb 101 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 5 94 1.3E-22 T 06-07-2017 IPR008407 Branched-chain amino acid transport, AzlD GTHT12_RS12700 02c82bf4490b7f0923f268f01d756c3d 262 Gene3D G3DSA:3.20.70.20 32 55 2.7E-35 T 06-07-2017 GTHT12_RS12700 02c82bf4490b7f0923f268f01d756c3d 262 Gene3D G3DSA:3.20.70.20 123 262 2.7E-35 T 06-07-2017 GTHT12_RS12700 02c82bf4490b7f0923f268f01d756c3d 262 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 130 180 1.1E-7 T 06-07-2017 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GTHT12_RS12700 02c82bf4490b7f0923f268f01d756c3d 262 Pfam PF02867 Ribonucleotide reductase, barrel domain 187 262 2.8E-12 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 GTHT12_RS12700 02c82bf4490b7f0923f268f01d756c3d 262 SUPERFAMILY SSF51998 130 262 1.16E-33 T 06-07-2017 GTHT12_RS18710 f6a75a83b1b7bd00b89b40c6250ad21b 493 SUPERFAMILY SSF75005 6 330 7.85E-113 T 06-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain GTHT12_RS18710 f6a75a83b1b7bd00b89b40c6250ad21b 493 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 14 329 1.2E-100 T 06-07-2017 IPR013148 Glycosyl hydrolase family 32, N-terminal GTHT12_RS18710 f6a75a83b1b7bd00b89b40c6250ad21b 493 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 374 448 1.9E-16 T 06-07-2017 IPR013189 Glycosyl hydrolase family 32, C-terminal GTHT12_RS18710 f6a75a83b1b7bd00b89b40c6250ad21b 493 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 14 27 - T 06-07-2017 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 GTHT12_RS18710 f6a75a83b1b7bd00b89b40c6250ad21b 493 Gene3D G3DSA:2.115.10.20 19 243 4.8E-9 T 06-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain GTHT12_RS18710 f6a75a83b1b7bd00b89b40c6250ad21b 493 Gene3D G3DSA:2.60.120.560 300 477 1.8E-34 T 06-07-2017 IPR013189 Glycosyl hydrolase family 32, C-terminal GTHT12_RS18710 f6a75a83b1b7bd00b89b40c6250ad21b 493 SUPERFAMILY SSF49899 329 478 5.06E-31 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain GTHT12_RS18710 f6a75a83b1b7bd00b89b40c6250ad21b 493 SMART SM00640 14 448 4.2E-161 T 06-07-2017 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 GTHT12_RS14575 b7fd495eea293708fe9a7256a5ba424f 571 ProSitePatterns PS00455 Putative AMP-binding domain signature. 211 222 - T 06-07-2017 IPR020845 AMP-binding, conserved site GTHT12_RS14575 b7fd495eea293708fe9a7256a5ba424f 571 SUPERFAMILY SSF56801 12 561 8.77E-164 T 06-07-2017 GTHT12_RS14575 b7fd495eea293708fe9a7256a5ba424f 571 Gene3D G3DSA:3.40.50.980 46 216 1.2E-34 T 06-07-2017 GTHT12_RS14575 b7fd495eea293708fe9a7256a5ba424f 571 Gene3D G3DSA:3.40.50.980 217 377 1.1E-37 T 06-07-2017 GTHT12_RS14575 b7fd495eea293708fe9a7256a5ba424f 571 Gene3D G3DSA:3.30.300.30 456 562 7.5E-30 T 06-07-2017 GTHT12_RS14575 b7fd495eea293708fe9a7256a5ba424f 571 Pfam PF00501 AMP-binding enzyme 51 461 7.4E-93 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GTHT12_RS14575 b7fd495eea293708fe9a7256a5ba424f 571 Pfam PF13193 AMP-binding enzyme C-terminal domain 470 548 2.1E-25 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain GTHT12_RS14575 b7fd495eea293708fe9a7256a5ba424f 571 Gene3D G3DSA:2.30.38.10 378 451 2.6E-19 T 06-07-2017 GTHT12_RS00175 76a7df939e5e1b241f7becb8efd714ac 330 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 17 197 2.7E-60 T 06-07-2017 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 GTHT12_RS00175 76a7df939e5e1b241f7becb8efd714ac 330 Gene3D G3DSA:3.40.50.300 12 169 8.8E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00175 76a7df939e5e1b241f7becb8efd714ac 330 Pfam PF13177 DNA polymerase III, delta subunit 12 170 6.1E-56 T 06-07-2017 GTHT12_RS00175 76a7df939e5e1b241f7becb8efd714ac 330 SUPERFAMILY SSF52540 12 196 3.04E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06795 2e2976ebff3a8636f255049120ed83ca 315 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 5 303 32.004 T 06-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 GTHT12_RS06795 2e2976ebff3a8636f255049120ed83ca 315 SUPERFAMILY SSF52540 5 160 7.19E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06795 2e2976ebff3a8636f255049120ed83ca 315 SUPERFAMILY SSF52540 159 262 2.28E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06795 2e2976ebff3a8636f255049120ed83ca 315 SUPERFAMILY SSF52540 4 50 2.28E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06795 2e2976ebff3a8636f255049120ed83ca 315 SUPERFAMILY SSF52540 122 130 2.28E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06795 2e2976ebff3a8636f255049120ed83ca 315 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 5 291 1.6E-114 T 06-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 GTHT12_RS06795 2e2976ebff3a8636f255049120ed83ca 315 Gene3D G3DSA:3.40.50.300 2 173 2.0E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06795 2e2976ebff3a8636f255049120ed83ca 315 Gene3D G3DSA:1.10.287.890 200 281 7.4E-33 T 06-07-2017 GTHT12_RS06795 2e2976ebff3a8636f255049120ed83ca 315 Pfam PF01715 IPP transferase 38 282 2.9E-89 T 06-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 GTHT12_RS18730 1c2e378badd10a1eca2c741108b5b960 77 SUPERFAMILY SSF56349 6 74 1.12E-15 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 GTHT12_RS18730 1c2e378badd10a1eca2c741108b5b960 77 Pfam PF00589 Phage integrase family 14 63 4.9E-12 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS18730 1c2e378badd10a1eca2c741108b5b960 77 Gene3D G3DSA:1.10.443.10 6 75 4.8E-17 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS11865 a3ec6ce366e11dc63c91b0385ea5de0a 189 Gene3D G3DSA:1.20.1260.10 1 182 8.8E-73 T 06-07-2017 IPR012347 Ferritin-related GTHT12_RS11865 a3ec6ce366e11dc63c91b0385ea5de0a 189 SUPERFAMILY SSF47240 1 186 1.65E-68 T 06-07-2017 IPR009078 Ferritin-like superfamily GTHT12_RS11865 a3ec6ce366e11dc63c91b0385ea5de0a 189 Pfam PF05067 Manganese containing catalase 1 184 3.1E-74 T 06-07-2017 IPR007760 Manganese catalase GTHT12_RS03945 9d3d6fcb4823b65d64c6e80e5a36c551 287 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 179 207 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GTHT12_RS03945 9d3d6fcb4823b65d64c6e80e5a36c551 287 SUPERFAMILY SSF51735 42 283 4.74E-84 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS03945 9d3d6fcb4823b65d64c6e80e5a36c551 287 Gene3D G3DSA:3.40.50.720 39 283 2.4E-88 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS03945 9d3d6fcb4823b65d64c6e80e5a36c551 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 172 180 2.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS03945 9d3d6fcb4823b65d64c6e80e5a36c551 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 192 211 2.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS03945 9d3d6fcb4823b65d64c6e80e5a36c551 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 131 2.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS03945 9d3d6fcb4823b65d64c6e80e5a36c551 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 131 3.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS03945 9d3d6fcb4823b65d64c6e80e5a36c551 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 45 62 3.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS03945 9d3d6fcb4823b65d64c6e80e5a36c551 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 182 3.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS03945 9d3d6fcb4823b65d64c6e80e5a36c551 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 211 3.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS03945 9d3d6fcb4823b65d64c6e80e5a36c551 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 230 3.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS03945 9d3d6fcb4823b65d64c6e80e5a36c551 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 247 267 3.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS03945 9d3d6fcb4823b65d64c6e80e5a36c551 287 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 53 282 2.8E-66 T 06-07-2017 GTHT12_RS17925 55de8405d2c2cc02c2137dc13d419a37 462 ProSitePatterns PS00218 Amino acid permeases signature. 41 71 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 GTHT12_RS17925 55de8405d2c2cc02c2137dc13d419a37 462 Pfam PF00324 Amino acid permease 16 454 2.2E-120 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 GTHT12_RS17925 55de8405d2c2cc02c2137dc13d419a37 462 PIRSF PIRSF006060 1 461 1.4E-77 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 GTHT12_RS16645 af3cb2d8c0deadd559ab33d445e37465 209 Gene3D G3DSA:3.50.30.50 3 205 2.3E-57 T 06-07-2017 GTHT12_RS16645 af3cb2d8c0deadd559ab33d445e37465 209 Hamap MF_01969 Kynurenine formamidase [kynB]. 4 208 42.353 T 06-07-2017 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 GTHT12_RS16645 af3cb2d8c0deadd559ab33d445e37465 209 TIGRFAM TIGR03035 trp_arylform: arylformamidase 5 208 3.0E-82 T 06-07-2017 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 GTHT12_RS16645 af3cb2d8c0deadd559ab33d445e37465 209 SUPERFAMILY SSF102198 2 206 1.15E-58 T 06-07-2017 GTHT12_RS16645 af3cb2d8c0deadd559ab33d445e37465 209 Pfam PF04199 Putative cyclase 6 151 3.1E-21 T 06-07-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 GTHT12_RS04335 fe754409b77b9bc22d3e0d04e847f8c1 132 Pfam PF03960 ArsC family 5 113 2.6E-23 T 06-07-2017 IPR006660 Arsenate reductase-like GTHT12_RS04335 fe754409b77b9bc22d3e0d04e847f8c1 132 Gene3D G3DSA:3.40.30.10 1 127 3.6E-35 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS04335 fe754409b77b9bc22d3e0d04e847f8c1 132 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 38.23 T 06-07-2017 IPR023731 Regulatory protein Spx GO:0045892 GTHT12_RS04335 fe754409b77b9bc22d3e0d04e847f8c1 132 SUPERFAMILY SSF52833 1 129 4.49E-40 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS04335 fe754409b77b9bc22d3e0d04e847f8c1 132 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 114 4.9E-37 T 06-07-2017 IPR006504 Transcriptional regulator Spx/MgsR GTHT12_RS13695 280afad528e5690da4a37cf800660ed9 222 Gene3D G3DSA:3.30.70.60 123 190 9.4E-4 T 06-07-2017 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 GTHT12_RS03050 508bb712c404758efbf0005c3b606475 390 Gene3D G3DSA:3.40.1660.10 260 379 2.9E-32 T 06-07-2017 GTHT12_RS03050 508bb712c404758efbf0005c3b606475 390 Gene3D G3DSA:3.40.1660.10 5 62 2.9E-32 T 06-07-2017 GTHT12_RS03050 508bb712c404758efbf0005c3b606475 390 SUPERFAMILY SSF159501 6 379 9.94E-66 T 06-07-2017 GTHT12_RS03050 508bb712c404758efbf0005c3b606475 390 Pfam PF05139 Erythromycin esterase 61 374 1.5E-31 T 06-07-2017 IPR007815 Erythromycin esterase GO:0046677 GTHT12_RS13055 39119efb5165533e03edc4810e9a0ed8 156 SUPERFAMILY SSF55486 2 155 1.83E-46 T 06-07-2017 GTHT12_RS13055 39119efb5165533e03edc4810e9a0ed8 156 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 122 132 - T 06-07-2017 IPR020549 Endoribonuclease YbeY, conserved site GTHT12_RS13055 39119efb5165533e03edc4810e9a0ed8 156 Gene3D G3DSA:3.40.390.30 7 155 1.7E-50 T 06-07-2017 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 GTHT12_RS13055 39119efb5165533e03edc4810e9a0ed8 156 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 40 152 6.2E-42 T 06-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 GTHT12_RS13055 39119efb5165533e03edc4810e9a0ed8 156 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 156 24.625 T 06-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 GTHT12_RS13055 39119efb5165533e03edc4810e9a0ed8 156 Pfam PF02130 Uncharacterized protein family UPF0054 15 152 4.0E-48 T 06-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 GTHT12_RS00240 72225d3be077ae0f2e92874cdbec4b5b 52 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 3 47 1.8E-4 T 06-07-2017 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 GTHT12_RS00240 72225d3be077ae0f2e92874cdbec4b5b 52 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 6 15 - T 06-07-2017 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 GTHT12_RS17435 8f7701a58414b519de453d0400fd924b 173 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 19 162 1.6E-36 T 06-07-2017 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS05955 ba724fc919af216e8ee614db855b2fb5 90 Pfam PF02325 YGGT family 10 76 6.7E-24 T 06-07-2017 IPR003425 CCB3/YggT GO:0016020 GTHT12_RS05085 d00b25170531c0cc3d6196aa080b290f 672 Pfam PF00326 Prolyl oligopeptidase family 457 668 3.6E-57 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 GTHT12_RS05085 d00b25170531c0cc3d6196aa080b290f 672 SUPERFAMILY SSF82171 21 404 6.8E-48 T 06-07-2017 GTHT12_RS05085 d00b25170531c0cc3d6196aa080b290f 672 Gene3D G3DSA:2.120.10.30 331 411 2.8E-8 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like GTHT12_RS05085 d00b25170531c0cc3d6196aa080b290f 672 Gene3D G3DSA:2.120.10.30 179 330 3.7E-50 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like GTHT12_RS05085 d00b25170531c0cc3d6196aa080b290f 672 Gene3D G3DSA:2.120.10.30 23 138 3.7E-50 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like GTHT12_RS05085 d00b25170531c0cc3d6196aa080b290f 672 SUPERFAMILY SSF53474 412 668 3.52E-72 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS05085 d00b25170531c0cc3d6196aa080b290f 672 Pfam PF07676 WD40-like Beta Propeller Repeat 242 263 0.039 T 06-07-2017 IPR011659 WD40-like Beta Propeller GTHT12_RS05085 d00b25170531c0cc3d6196aa080b290f 672 Pfam PF07676 WD40-like Beta Propeller Repeat 70 96 5.9E-7 T 06-07-2017 IPR011659 WD40-like Beta Propeller GTHT12_RS05085 d00b25170531c0cc3d6196aa080b290f 672 Pfam PF07676 WD40-like Beta Propeller Repeat 192 223 1.2E-4 T 06-07-2017 IPR011659 WD40-like Beta Propeller GTHT12_RS05085 d00b25170531c0cc3d6196aa080b290f 672 Gene3D G3DSA:3.40.50.1820 412 669 2.5E-72 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS16710 3852cae12fd94c8be8330f6d74c6c123 490 Pfam PF00474 Sodium:solute symporter family 35 428 7.0E-24 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 GTHT12_RS03685 c4989d1a173f7c773c2532caabad0c34 345 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 6 342 47.52 T 06-07-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 GTHT12_RS03685 c4989d1a173f7c773c2532caabad0c34 345 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 22 31 - T 06-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 GTHT12_RS03685 c4989d1a173f7c773c2532caabad0c34 345 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 6 341 1.1E-124 T 06-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 GTHT12_RS03685 c4989d1a173f7c773c2532caabad0c34 345 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 8 339 4.9E-128 T 06-07-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 GTHT12_RS03685 c4989d1a173f7c773c2532caabad0c34 345 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 140 156 - T 06-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 GTHT12_RS03685 c4989d1a173f7c773c2532caabad0c34 345 Gene3D G3DSA:3.20.20.210 6 342 1.0E-134 T 06-07-2017 GTHT12_RS03685 c4989d1a173f7c773c2532caabad0c34 345 SUPERFAMILY SSF51726 3 342 2.88E-105 T 06-07-2017 GTHT12_RS03780 34d4c376b03ffb03b13f65dcb8c79aec 184 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 17 177 9.6E-53 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 GTHT12_RS03780 34d4c376b03ffb03b13f65dcb8c79aec 184 ProSitePatterns PS00501 Signal peptidases I serine active site. 38 45 - T 06-07-2017 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 GTHT12_RS03780 34d4c376b03ffb03b13f65dcb8c79aec 184 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 137 156 2.7E-21 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 GTHT12_RS03780 34d4c376b03ffb03b13f65dcb8c79aec 184 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 29 45 2.7E-21 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 GTHT12_RS03780 34d4c376b03ffb03b13f65dcb8c79aec 184 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 79 91 2.7E-21 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 GTHT12_RS03780 34d4c376b03ffb03b13f65dcb8c79aec 184 ProSitePatterns PS00761 Signal peptidases I signature 3. 142 155 - T 06-07-2017 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 GTHT12_RS03780 34d4c376b03ffb03b13f65dcb8c79aec 184 ProSitePatterns PS00760 Signal peptidases I lysine active site. 81 93 - T 06-07-2017 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 GTHT12_RS03780 34d4c376b03ffb03b13f65dcb8c79aec 184 Pfam PF00717 Peptidase S24-like 36 103 1.6E-21 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B GTHT12_RS03780 34d4c376b03ffb03b13f65dcb8c79aec 184 Gene3D G3DSA:2.10.109.10 26 89 9.7E-40 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain GTHT12_RS03780 34d4c376b03ffb03b13f65dcb8c79aec 184 Gene3D G3DSA:2.10.109.10 137 181 9.7E-40 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain GTHT12_RS03780 34d4c376b03ffb03b13f65dcb8c79aec 184 SUPERFAMILY SSF51306 27 182 1.74E-55 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C GTHT12_RS11960 7b8da953341ecec972b094621634ea2e 356 TIGRFAM TIGR01140 L_thr_O3P_dcar: threonine-phosphate decarboxylase 6 352 3.7E-98 T 06-07-2017 IPR005860 L-threonine-O-3-phosphate decarboxylase GO:0003824|GO:0009236 KEGG: 00860+4.1.1.81|MetaCyc: PWY-5443 GTHT12_RS11960 7b8da953341ecec972b094621634ea2e 356 Gene3D G3DSA:3.40.640.10 49 254 7.4E-63 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS11960 7b8da953341ecec972b094621634ea2e 356 Gene3D G3DSA:3.90.1150.10 255 353 1.0E-23 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS11960 7b8da953341ecec972b094621634ea2e 356 SUPERFAMILY SSF53383 17 353 3.13E-72 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS11960 7b8da953341ecec972b094621634ea2e 356 Pfam PF00155 Aminotransferase class I and II 26 351 3.2E-41 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 GTHT12_RS15565 4801c61d37953d74ad866f497ec227f0 300 Pfam PF01925 Sulfite exporter TauE/SafE 6 294 3.6E-58 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 GTHT12_RS11035 198f4fea775840537fb8b8412e3ea56e 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 312 6.3E-45 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS11035 198f4fea775840537fb8b8412e3ea56e 316 Gene3D G3DSA:1.10.3720.10 89 307 2.5E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS11035 198f4fea775840537fb8b8412e3ea56e 316 SUPERFAMILY SSF161098 91 297 3.14E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS05005 c21c7a9cce19b7a4d777babd60d82e3a 163 Gene3D G3DSA:1.10.10.10 78 160 3.5E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS05005 c21c7a9cce19b7a4d777babd60d82e3a 163 SUPERFAMILY SSF53155 13 84 1.29E-15 T 06-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 GTHT12_RS05005 c21c7a9cce19b7a4d777babd60d82e3a 163 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 3 162 35.596 T 06-07-2017 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 GTHT12_RS05005 c21c7a9cce19b7a4d777babd60d82e3a 163 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 81 160 1.0E-31 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 GTHT12_RS05005 c21c7a9cce19b7a4d777babd60d82e3a 163 SUPERFAMILY SSF46767 78 160 6.28E-30 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 GTHT12_RS05005 c21c7a9cce19b7a4d777babd60d82e3a 163 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 79 159 1.4E-35 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 GTHT12_RS05005 c21c7a9cce19b7a4d777babd60d82e3a 163 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 129 135 - T 06-07-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 GTHT12_RS07405 795ee6bcaaab29b276f062c522dd5a04 418 Pfam PF07075 Protein of unknown function (DUF1343) 55 417 7.2E-155 T 06-07-2017 IPR008302 Uncharacterised conserved protein UCP016719 GTHT12_RS07405 795ee6bcaaab29b276f062c522dd5a04 418 PIRSF PIRSF016719 1 418 1.5E-187 T 06-07-2017 IPR008302 Uncharacterised conserved protein UCP016719 GTHT12_RS10135 c235ed65d1195e5a9f367ed268debdd1 313 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 30 82 6.1E-13 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain GTHT12_RS10135 c235ed65d1195e5a9f367ed268debdd1 313 SUPERFAMILY SSF161098 98 296 5.63E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS10135 c235ed65d1195e5a9f367ed268debdd1 313 Gene3D G3DSA:1.10.3720.10 95 310 7.1E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS10135 c235ed65d1195e5a9f367ed268debdd1 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 129 312 4.1E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS16850 7a95b6892b89b3c6f21222f332e0e72b 312 Pfam PF00892 EamA-like transporter family 7 138 2.1E-21 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 GTHT12_RS16850 7a95b6892b89b3c6f21222f332e0e72b 312 Pfam PF00892 EamA-like transporter family 151 284 6.8E-19 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 GTHT12_RS16850 7a95b6892b89b3c6f21222f332e0e72b 312 SUPERFAMILY SSF103481 190 284 8.76E-17 T 06-07-2017 GTHT12_RS16850 7a95b6892b89b3c6f21222f332e0e72b 312 SUPERFAMILY SSF103481 39 141 1.23E-13 T 06-07-2017 GTHT12_RS06805 f38b257cbd6b9ab79e500c6b59437b3f 310 Gene3D G3DSA:3.40.50.300 46 237 7.0E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06805 f38b257cbd6b9ab79e500c6b59437b3f 310 SUPERFAMILY SSF52540 42 307 2.37E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06805 f38b257cbd6b9ab79e500c6b59437b3f 310 TIGRFAM TIGR02881 spore_V_K: stage V sporulation protein K 45 306 7.8E-134 T 06-07-2017 IPR014232 Sporulation stage V, protein K GTHT12_RS06805 f38b257cbd6b9ab79e500c6b59437b3f 310 PRINTS PR00819 CbxX/CfqX superfamily signature 48 62 2.8E-60 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 GTHT12_RS06805 f38b257cbd6b9ab79e500c6b59437b3f 310 PRINTS PR00819 CbxX/CfqX superfamily signature 140 159 2.8E-60 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 GTHT12_RS06805 f38b257cbd6b9ab79e500c6b59437b3f 310 PRINTS PR00819 CbxX/CfqX superfamily signature 88 103 2.8E-60 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 GTHT12_RS06805 f38b257cbd6b9ab79e500c6b59437b3f 310 PRINTS PR00819 CbxX/CfqX superfamily signature 191 208 2.8E-60 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 GTHT12_RS06805 f38b257cbd6b9ab79e500c6b59437b3f 310 PRINTS PR00819 CbxX/CfqX superfamily signature 208 227 2.8E-60 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 GTHT12_RS06805 f38b257cbd6b9ab79e500c6b59437b3f 310 PRINTS PR00819 CbxX/CfqX superfamily signature 170 182 2.8E-60 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 GTHT12_RS06805 f38b257cbd6b9ab79e500c6b59437b3f 310 PRINTS PR00819 CbxX/CfqX superfamily signature 126 140 2.8E-60 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 GTHT12_RS06805 f38b257cbd6b9ab79e500c6b59437b3f 310 PRINTS PR00819 CbxX/CfqX superfamily signature 268 280 2.8E-60 T 06-07-2017 IPR000641 CbxX/CfqX GO:0005524 GTHT12_RS06805 f38b257cbd6b9ab79e500c6b59437b3f 310 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 89 219 3.0E-18 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 GTHT12_RS06805 f38b257cbd6b9ab79e500c6b59437b3f 310 SMART SM00382 85 223 2.9E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS13390 b0de6dbdcafd4e4f16fc750597be5439 44 Pfam PF13056 Protein of unknown function (DUF3918) 1 43 1.2E-20 T 06-07-2017 IPR025029 Protein of unknown function DUF3918 GTHT12_RS02810 30ff25d06ca32e91714f21ef6583b9e9 261 Gene3D G3DSA:1.10.490.50 172 257 2.9E-29 T 06-07-2017 IPR012925 TipAS antibiotic-recognition domain GTHT12_RS02810 30ff25d06ca32e91714f21ef6583b9e9 261 SUPERFAMILY SSF89082 170 259 5.89E-29 T 06-07-2017 IPR012925 TipAS antibiotic-recognition domain GTHT12_RS02810 30ff25d06ca32e91714f21ef6583b9e9 261 SMART SM00422 10 79 3.6E-26 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS02810 30ff25d06ca32e91714f21ef6583b9e9 261 SUPERFAMILY SSF46955 10 112 7.69E-29 T 06-07-2017 IPR009061 Putative DNA-binding domain GTHT12_RS02810 30ff25d06ca32e91714f21ef6583b9e9 261 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 22 35 2.0E-6 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS02810 30ff25d06ca32e91714f21ef6583b9e9 261 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 2.0E-6 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS02810 30ff25d06ca32e91714f21ef6583b9e9 261 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 11 22 2.0E-6 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS02810 30ff25d06ca32e91714f21ef6583b9e9 261 Pfam PF13411 MerR HTH family regulatory protein 10 77 5.7E-18 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 GTHT12_RS02810 30ff25d06ca32e91714f21ef6583b9e9 261 Pfam PF07739 TipAS antibiotic-recognition domain 142 256 1.2E-36 T 06-07-2017 IPR012925 TipAS antibiotic-recognition domain GTHT12_RS02810 30ff25d06ca32e91714f21ef6583b9e9 261 Gene3D G3DSA:1.10.1660.10 10 121 1.9E-29 T 06-07-2017 GTHT12_RS14260 6e19a4eb013ef439e26f7f3ae7fc62b8 325 SUPERFAMILY SSF52096 6 314 1.36E-102 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS14260 6e19a4eb013ef439e26f7f3ae7fc62b8 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 133 149 9.8E-47 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 GTHT12_RS14260 6e19a4eb013ef439e26f7f3ae7fc62b8 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 168 181 9.8E-47 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 GTHT12_RS14260 6e19a4eb013ef439e26f7f3ae7fc62b8 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 196 205 9.8E-47 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 GTHT12_RS14260 6e19a4eb013ef439e26f7f3ae7fc62b8 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 87 98 9.8E-47 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 GTHT12_RS14260 6e19a4eb013ef439e26f7f3ae7fc62b8 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 152 165 9.8E-47 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 GTHT12_RS14260 6e19a4eb013ef439e26f7f3ae7fc62b8 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 112 130 9.8E-47 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 GTHT12_RS14260 6e19a4eb013ef439e26f7f3ae7fc62b8 325 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 4 315 49.837 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 GTHT12_RS14260 6e19a4eb013ef439e26f7f3ae7fc62b8 325 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 316 3.6E-158 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 GTHT12_RS14260 6e19a4eb013ef439e26f7f3ae7fc62b8 325 Gene3D G3DSA:3.90.226.10 55 266 3.0E-50 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS14260 6e19a4eb013ef439e26f7f3ae7fc62b8 325 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 147 4.2E-66 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 GTHT12_RS13705 eab92a76d427be577e74d1835e1d4f16 310 Pfam PF11104 Type IV pilus assembly protein PilM; 36 209 3.8E-14 T 06-07-2017 IPR005883 Type IV pilus assembly protein PilM GTHT12_RS13705 eab92a76d427be577e74d1835e1d4f16 310 SUPERFAMILY SSF53067 65 167 3.82E-7 T 06-07-2017 GTHT12_RS08030 62e8e279a062437938d4ba0f7d6acfa1 282 SUPERFAMILY SSF52821 4 152 2.1E-43 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS08030 62e8e279a062437938d4ba0f7d6acfa1 282 Gene3D G3DSA:3.40.250.10 150 277 1.5E-32 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS08030 62e8e279a062437938d4ba0f7d6acfa1 282 Gene3D G3DSA:3.40.250.10 3 149 2.9E-49 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS08030 62e8e279a062437938d4ba0f7d6acfa1 282 SMART SM00450 154 271 2.2E-18 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS08030 62e8e279a062437938d4ba0f7d6acfa1 282 SMART SM00450 5 131 6.4E-24 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS08030 62e8e279a062437938d4ba0f7d6acfa1 282 Pfam PF00581 Rhodanese-like domain 156 266 5.6E-13 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS08030 62e8e279a062437938d4ba0f7d6acfa1 282 Pfam PF00581 Rhodanese-like domain 6 127 6.4E-20 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS08030 62e8e279a062437938d4ba0f7d6acfa1 282 SUPERFAMILY SSF52821 149 278 3.4E-33 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS06555 afd51c9ee5acb5d6c4083e36d89a26a0 92 Gene3D G3DSA:3.30.70.1120 1 92 2.3E-30 T 06-07-2017 IPR007546 Protein of unknown function DUF503 GTHT12_RS06555 afd51c9ee5acb5d6c4083e36d89a26a0 92 Pfam PF04456 Protein of unknown function (DUF503) 2 85 2.7E-28 T 06-07-2017 IPR007546 Protein of unknown function DUF503 GTHT12_RS06555 afd51c9ee5acb5d6c4083e36d89a26a0 92 SUPERFAMILY SSF103007 1 92 3.66E-29 T 06-07-2017 IPR007546 Protein of unknown function DUF503 GTHT12_RS07615 847019040f07105b2ae44e343c98edce 134 Pfam PF07485 Domain of Unknown Function (DUF1259) 12 130 2.5E-38 T 06-07-2017 IPR011094 Uncharacterised protein family, LppY/LpqO GTHT12_RS14800 1a1ff3a7b3ad32c3ebe7579cc7e2d4a7 334 Gene3D G3DSA:3.40.190.10 134 244 9.3E-6 T 06-07-2017 GTHT12_RS14800 1a1ff3a7b3ad32c3ebe7579cc7e2d4a7 334 SUPERFAMILY SSF53850 40 256 3.05E-35 T 06-07-2017 GTHT12_RS14800 1a1ff3a7b3ad32c3ebe7579cc7e2d4a7 334 Pfam PF09084 NMT1/THI5 like 46 255 1.2E-21 T 06-07-2017 IPR015168 SsuA/THI5-like GTHT12_RS01160 a9679bc810278b8478208eb2b782f793 335 SUPERFAMILY SSF81345 5 329 3.66E-78 T 06-07-2017 IPR029022 ABC transporter, BtuC-like GTHT12_RS01160 a9679bc810278b8478208eb2b782f793 335 Gene3D G3DSA:1.10.3470.10 12 332 8.3E-92 T 06-07-2017 IPR029022 ABC transporter, BtuC-like GTHT12_RS01160 a9679bc810278b8478208eb2b782f793 335 Pfam PF01032 FecCD transport family 20 329 5.4E-85 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 GTHT12_RS09610 9901ee3e1f4315b47adf4b32351c1995 453 Gene3D G3DSA:3.90.350.10 292 348 8.1E-7 T 06-07-2017 IPR014736 Transposase, Tn5-like, core GTHT12_RS09610 9901ee3e1f4315b47adf4b32351c1995 453 Pfam PF13546 DDE superfamily endonuclease 73 256 4.1E-23 T 06-07-2017 GTHT12_RS09610 9901ee3e1f4315b47adf4b32351c1995 453 SUPERFAMILY SSF53098 50 412 4.48E-48 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS03435 ea0cc02177e8a584ce8c2c3c4747ef67 90 PIRSF PIRSF029962 1 90 1.8E-38 T 06-07-2017 IPR016941 Uncharacterised conserved protein UCP029962 GTHT12_RS03435 ea0cc02177e8a584ce8c2c3c4747ef67 90 Pfam PF06803 Protein of unknown function (DUF1232) 39 71 6.9E-9 T 06-07-2017 IPR010652 Protein of unknown function DUF1232 GTHT12_RS08120 6ab2c017902eab38728c43df83994e9b 111 Pfam PF14191 YodL-like 25 89 4.2E-5 T 06-07-2017 IPR025923 YodL-like GTHT12_RS08120 6ab2c017902eab38728c43df83994e9b 111 ProDom PD030115 YODL GK1575 15 103 1.0E-37 T 06-07-2017 GTHT12_RS12610 07b5929b01778512b074e67af68c7abd 353 Gene3D G3DSA:3.90.230.10 127 351 3.6E-90 T 06-07-2017 IPR000994 Peptidase M24, structural domain GTHT12_RS12610 07b5929b01778512b074e67af68c7abd 353 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 283 295 - T 06-07-2017 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site GTHT12_RS12610 07b5929b01778512b074e67af68c7abd 353 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 127 2.9E-29 T 06-07-2017 IPR000587 Creatinase, N-terminal GO:0016787 GTHT12_RS12610 07b5929b01778512b074e67af68c7abd 353 SUPERFAMILY SSF55920 83 348 5.89E-86 T 06-07-2017 IPR000994 Peptidase M24, structural domain GTHT12_RS12610 07b5929b01778512b074e67af68c7abd 353 SUPERFAMILY SSF53092 2 125 4.39E-28 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal GTHT12_RS12610 07b5929b01778512b074e67af68c7abd 353 Gene3D G3DSA:3.40.350.10 1 125 4.3E-33 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal GTHT12_RS12610 07b5929b01778512b074e67af68c7abd 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 274 286 4.2E-7 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase GTHT12_RS12610 07b5929b01778512b074e67af68c7abd 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 207 223 4.2E-7 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase GTHT12_RS12610 07b5929b01778512b074e67af68c7abd 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 305 317 4.2E-7 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase GTHT12_RS12610 07b5929b01778512b074e67af68c7abd 353 Pfam PF00557 Metallopeptidase family M24 136 336 6.0E-69 T 06-07-2017 IPR000994 Peptidase M24, structural domain GTHT12_RS13075 e72321b908dd0bb954a167e57c785bcf 96 Pfam PF07873 YabP family 28 91 3.3E-17 T 06-07-2017 IPR022476 Sporulation protein YabP/YqfC GTHT12_RS13075 e72321b908dd0bb954a167e57c785bcf 96 TIGRFAM TIGR02856 spore_yqfC: sporulation protein YqfC 9 92 1.7E-37 T 06-07-2017 IPR022477 Sporulation protein YqfC GTHT12_RS06195 3b5aa1eea6ce51c992d2218f3770e8df 246 Pfam PF14622 Ribonuclease-III-like 31 162 3.5E-37 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 GTHT12_RS06195 3b5aa1eea6ce51c992d2218f3770e8df 246 SUPERFAMILY SSF54768 130 240 6.13E-25 T 06-07-2017 GTHT12_RS06195 3b5aa1eea6ce51c992d2218f3770e8df 246 SMART SM00535 33 168 4.0E-58 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 GTHT12_RS06195 3b5aa1eea6ce51c992d2218f3770e8df 246 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 21 240 3.7E-81 T 06-07-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 GTHT12_RS06195 3b5aa1eea6ce51c992d2218f3770e8df 246 Pfam PF00035 Double-stranded RNA binding motif 175 240 3.7E-18 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain GTHT12_RS06195 3b5aa1eea6ce51c992d2218f3770e8df 246 Gene3D G3DSA:1.10.1520.10 17 166 1.1E-50 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 GTHT12_RS06195 3b5aa1eea6ce51c992d2218f3770e8df 246 SUPERFAMILY SSF69065 14 175 1.05E-53 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 GTHT12_RS06195 3b5aa1eea6ce51c992d2218f3770e8df 246 Gene3D G3DSA:3.30.160.20 173 240 1.3E-27 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain GTHT12_RS06195 3b5aa1eea6ce51c992d2218f3770e8df 246 Hamap MF_00104 Ribonuclease 3 [rnc]. 21 237 32.031 T 06-07-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 GTHT12_RS06195 3b5aa1eea6ce51c992d2218f3770e8df 246 ProSitePatterns PS00517 Ribonuclease III family signature. 57 65 - T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 GTHT12_RS06195 3b5aa1eea6ce51c992d2218f3770e8df 246 SMART SM00358 174 241 3.0E-21 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain GTHT12_RS09685 5b471440617353ac713ef39a81f4f719 609 SMART SM00267 225 400 8.8E-50 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS09685 5b471440617353ac713ef39a81f4f719 609 Pfam PF01966 HD domain 433 556 4.1E-20 T 06-07-2017 IPR006674 HD domain GTHT12_RS09685 5b471440617353ac713ef39a81f4f719 609 SUPERFAMILY SSF109604 422 595 1.26E-33 T 06-07-2017 GTHT12_RS09685 5b471440617353ac713ef39a81f4f719 609 Pfam PF00990 Diguanylate cyclase, GGDEF domain 236 396 3.6E-40 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS09685 5b471440617353ac713ef39a81f4f719 609 SMART SM00471 429 565 7.0E-12 T 06-07-2017 IPR003607 HD/PDEase domain GTHT12_RS09685 5b471440617353ac713ef39a81f4f719 609 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 234 399 3.2E-42 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS09685 5b471440617353ac713ef39a81f4f719 609 SUPERFAMILY SSF55073 241 402 1.41E-43 T 06-07-2017 IPR029787 Nucleotide cyclase GTHT12_RS09685 5b471440617353ac713ef39a81f4f719 609 Gene3D G3DSA:1.10.3210.10 415 592 3.5E-21 T 06-07-2017 IPR006674 HD domain GTHT12_RS09685 5b471440617353ac713ef39a81f4f719 609 Gene3D G3DSA:3.30.70.270 238 403 1.1E-46 T 06-07-2017 GTHT12_RS06350 3a5a5be8f6b3934269bb7453813cc3ae 148 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 5 144 6.4E-26 T 06-07-2017 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 GTHT12_RS06350 3a5a5be8f6b3934269bb7453813cc3ae 148 Pfam PF02050 Flagellar FliJ protein 19 142 1.1E-22 T 06-07-2017 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 GTHT12_RS06350 3a5a5be8f6b3934269bb7453813cc3ae 148 Gene3D G3DSA:1.25.40.10 14 128 7.9E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 GTHT12_RS05880 4c8665809f806c170c63acf35eec5ef9 366 Pfam PF01098 Cell cycle protein 12 365 3.2E-131 T 06-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 GTHT12_RS05880 4c8665809f806c170c63acf35eec5ef9 366 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 9 363 4.0E-135 T 06-07-2017 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 GTHT12_RS05880 4c8665809f806c170c63acf35eec5ef9 366 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 9 364 4.3E-103 T 06-07-2017 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 GTHT12_RS05880 4c8665809f806c170c63acf35eec5ef9 366 TIGRFAM TIGR02615 spoVE: stage V sporulation protein E 9 362 1.6E-182 T 06-07-2017 IPR013438 Sporulation stage V, protein E GTHT12_RS05880 4c8665809f806c170c63acf35eec5ef9 366 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 322 346 - T 06-07-2017 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 GTHT12_RS14075 fb890c23736bf9c07fa2ec18ae8218b6 424 PRINTS PR00113 Alkaline phosphatase signature 93 108 2.1E-42 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 GTHT12_RS14075 fb890c23736bf9c07fa2ec18ae8218b6 424 PRINTS PR00113 Alkaline phosphatase signature 175 185 2.1E-42 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 GTHT12_RS14075 fb890c23736bf9c07fa2ec18ae8218b6 424 PRINTS PR00113 Alkaline phosphatase signature 41 61 2.1E-42 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 GTHT12_RS14075 fb890c23736bf9c07fa2ec18ae8218b6 424 PRINTS PR00113 Alkaline phosphatase signature 265 294 2.1E-42 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 GTHT12_RS14075 fb890c23736bf9c07fa2ec18ae8218b6 424 PRINTS PR00113 Alkaline phosphatase signature 130 150 2.1E-42 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 GTHT12_RS14075 fb890c23736bf9c07fa2ec18ae8218b6 424 Gene3D G3DSA:3.40.720.10 21 418 1.9E-126 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 GTHT12_RS14075 fb890c23736bf9c07fa2ec18ae8218b6 424 Pfam PF00245 Alkaline phosphatase 371 417 6.7E-6 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 GTHT12_RS14075 fb890c23736bf9c07fa2ec18ae8218b6 424 Pfam PF00245 Alkaline phosphatase 42 349 3.7E-86 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 GTHT12_RS14075 fb890c23736bf9c07fa2ec18ae8218b6 424 SMART SM00098 42 421 2.1E-78 T 06-07-2017 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 GTHT12_RS14075 fb890c23736bf9c07fa2ec18ae8218b6 424 SUPERFAMILY SSF53649 23 416 6.54E-118 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 GTHT12_RS12500 7103ca17507973a0d635c0a05427ac45 149 PRINTS PR01467 Bacterial arginine repressor signature 21 34 2.6E-29 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 GTHT12_RS12500 7103ca17507973a0d635c0a05427ac45 149 PRINTS PR01467 Bacterial arginine repressor signature 37 52 2.6E-29 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 GTHT12_RS12500 7103ca17507973a0d635c0a05427ac45 149 PRINTS PR01467 Bacterial arginine repressor signature 88 101 2.6E-29 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 GTHT12_RS12500 7103ca17507973a0d635c0a05427ac45 149 PRINTS PR01467 Bacterial arginine repressor signature 118 133 2.6E-29 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 GTHT12_RS12500 7103ca17507973a0d635c0a05427ac45 149 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 148 4.2E-53 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 GTHT12_RS12500 7103ca17507973a0d635c0a05427ac45 149 Gene3D G3DSA:3.30.1360.40 73 148 1.6E-28 T 06-07-2017 IPR024946 Arginine repressor C-terminal-like domain GTHT12_RS12500 7103ca17507973a0d635c0a05427ac45 149 Gene3D G3DSA:1.10.10.10 9 66 1.9E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12500 7103ca17507973a0d635c0a05427ac45 149 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 87 149 2.0E-29 T 06-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 GTHT12_RS12500 7103ca17507973a0d635c0a05427ac45 149 Pfam PF01316 Arginine repressor, DNA binding domain 1 70 2.3E-32 T 06-07-2017 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 GTHT12_RS12500 7103ca17507973a0d635c0a05427ac45 149 SUPERFAMILY SSF46785 3 78 5.94E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12500 7103ca17507973a0d635c0a05427ac45 149 SUPERFAMILY SSF55252 80 149 7.06E-22 T 06-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 GTHT12_RS12500 7103ca17507973a0d635c0a05427ac45 149 Pfam PF02863 Arginine repressor, C-terminal domain 82 145 4.3E-25 T 06-07-2017 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 GTHT12_RS12500 7103ca17507973a0d635c0a05427ac45 149 Hamap MF_00173 Arginine repressor [argR]. 1 149 70.053 T 06-07-2017 IPR001669 Arginine repressor GO:0003700|GO:0006355 GTHT12_RS04360 bc22a79c52eff2e4ea41cd901ace9ed3 607 Gene3D G3DSA:3.40.390.10 389 432 4.5E-4 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 GTHT12_RS04360 bc22a79c52eff2e4ea41cd901ace9ed3 607 Pfam PF01432 Peptidase family M3 213 592 2.6E-82 T 06-07-2017 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 GTHT12_RS04360 bc22a79c52eff2e4ea41cd901ace9ed3 607 Pfam PF08439 Oligopeptidase F 122 191 1.6E-23 T 06-07-2017 IPR013647 Oligopeptidase F, N-terminal domain GTHT12_RS04360 bc22a79c52eff2e4ea41cd901ace9ed3 607 Gene3D G3DSA:1.10.287.830 190 235 3.1E-17 T 06-07-2017 GTHT12_RS04360 bc22a79c52eff2e4ea41cd901ace9ed3 607 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 15 603 2.9E-222 T 06-07-2017 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 GTHT12_RS04360 bc22a79c52eff2e4ea41cd901ace9ed3 607 SUPERFAMILY SSF55486 64 604 1.92E-143 T 06-07-2017 GTHT12_RS06310 33706f261302a2b718b970d596bc99b0 259 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 3 253 4.1E-127 T 06-07-2017 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 GTHT12_RS06310 33706f261302a2b718b970d596bc99b0 259 PIRSF PIRSF011572 1 257 2.9E-125 T 06-07-2017 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 GTHT12_RS06310 33706f261302a2b718b970d596bc99b0 259 SUPERFAMILY SSF46785 167 256 5.86E-43 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS06310 33706f261302a2b718b970d596bc99b0 259 Pfam PF06018 CodY GAF-like domain 2 178 9.4E-83 T 06-07-2017 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 GTHT12_RS06310 33706f261302a2b718b970d596bc99b0 259 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 259 152.995 T 06-07-2017 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 GTHT12_RS06310 33706f261302a2b718b970d596bc99b0 259 Gene3D G3DSA:1.10.10.10 180 248 2.9E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS06310 33706f261302a2b718b970d596bc99b0 259 Pfam PF08222 CodY helix-turn-helix domain 197 257 2.0E-38 T 06-07-2017 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal GTHT12_RS01680 c70f2a0e8b683ac198ee2a8536ae880f 724 Gene3D G3DSA:3.40.50.300 191 288 3.1E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01680 c70f2a0e8b683ac198ee2a8536ae880f 724 Gene3D G3DSA:3.40.50.300 6 112 3.1E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01680 c70f2a0e8b683ac198ee2a8536ae880f 724 SUPERFAMILY SSF52540 1 647 1.58E-197 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01680 c70f2a0e8b683ac198ee2a8536ae880f 724 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 8 722 0.0 T 06-07-2017 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 GTHT12_RS01680 c70f2a0e8b683ac198ee2a8536ae880f 724 Gene3D G3DSA:1.10.10.160 116 189 1.1E-28 T 06-07-2017 IPR013986 DExx box DNA helicase domain GTHT12_RS01680 c70f2a0e8b683ac198ee2a8536ae880f 724 Gene3D G3DSA:3.40.50.300 289 391 3.9E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01680 c70f2a0e8b683ac198ee2a8536ae880f 724 Gene3D G3DSA:3.40.50.300 557 648 3.9E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS01680 c70f2a0e8b683ac198ee2a8536ae880f 724 Pfam PF13361 UvrD-like helicase C-terminal domain 280 620 4.9E-74 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 GTHT12_RS01680 c70f2a0e8b683ac198ee2a8536ae880f 724 Pfam PF00580 UvrD/REP helicase N-terminal domain 12 274 7.5E-87 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 GTHT12_RS01680 c70f2a0e8b683ac198ee2a8536ae880f 724 Gene3D G3DSA:1.10.486.10 392 537 1.4E-53 T 06-07-2017 GTHT12_RS05825 81b9af4ca744c2dc0779d0d99817808e 296 SUPERFAMILY SSF48179 170 290 4.08E-29 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 GTHT12_RS05825 81b9af4ca744c2dc0779d0d99817808e 296 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 291 5.0E-69 T 06-07-2017 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 GTHT12_RS05825 81b9af4ca744c2dc0779d0d99817808e 296 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 171 290 1.1E-29 T 06-07-2017 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 GTHT12_RS05825 81b9af4ca744c2dc0779d0d99817808e 296 SUPERFAMILY SSF51735 1 149 5.66E-19 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS05825 81b9af4ca744c2dc0779d0d99817808e 296 Gene3D G3DSA:3.40.50.720 1 178 1.4E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS05825 81b9af4ca744c2dc0779d0d99817808e 296 Gene3D G3DSA:1.10.1040.10 179 290 1.3E-33 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 GTHT12_RS05825 81b9af4ca744c2dc0779d0d99817808e 296 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 146 5.7E-24 T 06-07-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 Gene3D G3DSA:3.50.50.60 11 143 5.8E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 PIRSF PIRSF000350 3 457 6.9E-102 T 06-07-2017 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 SUPERFAMILY SSF55424 344 467 8.42E-42 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 452 2.3E-37 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 8.4E-44 T 06-07-2017 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 8.4E-44 T 06-07-2017 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 281 8.4E-44 T 06-07-2017 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 8.4E-44 T 06-07-2017 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 316 8.4E-44 T 06-07-2017 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 280 1.4E-76 T 06-07-2017 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 309 316 1.4E-76 T 06-07-2017 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 1.4E-76 T 06-07-2017 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 1.4E-76 T 06-07-2017 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 1.4E-76 T 06-07-2017 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 1.4E-76 T 06-07-2017 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 1.4E-76 T 06-07-2017 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 1.4E-76 T 06-07-2017 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 1.4E-76 T 06-07-2017 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 SUPERFAMILY SSF51905 9 339 5.55E-70 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 Gene3D G3DSA:3.30.390.30 336 466 1.8E-48 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 10 467 4.3E-179 T 06-07-2017 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 329 1.0E-75 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 Gene3D G3DSA:3.50.50.60 144 335 6.9E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS05590 6e18c89e0f88103f45275248316a7475 470 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 06-07-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 GTHT12_RS15580 a245f4a37a1add7fd5c8a1aed0e68c4a 465 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 10 456 2.1E-232 T 06-07-2017 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 GTHT12_RS15580 a245f4a37a1add7fd5c8a1aed0e68c4a 465 Pfam PF01458 Uncharacterized protein family (UPF0051) 211 436 3.5E-75 T 06-07-2017 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 GTHT12_RS15580 a245f4a37a1add7fd5c8a1aed0e68c4a 465 SUPERFAMILY SSF101960 32 462 6.8E-142 T 06-07-2017 GTHT12_RS16085 5c869874f264e9977ffbbfd4219ec2f8 443 Gene3D G3DSA:1.10.287.950 37 122 7.6E-5 T 06-07-2017 GTHT12_RS16085 5c869874f264e9977ffbbfd4219ec2f8 443 SUPERFAMILY SSF51261 216 441 1.05E-44 T 06-07-2017 IPR011055 Duplicated hybrid motif GTHT12_RS16085 5c869874f264e9977ffbbfd4219ec2f8 443 Pfam PF01551 Peptidase family M23 333 436 9.1E-27 T 06-07-2017 IPR016047 Peptidase M23 GTHT12_RS16085 5c869874f264e9977ffbbfd4219ec2f8 443 Gene3D G3DSA:2.70.70.10 303 441 1.0E-38 T 06-07-2017 GTHT12_RS14000 8decc41d6cb3e30cf3103c557f73e266 104 SUPERFAMILY SSF52833 3 103 9.25E-39 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS14000 8decc41d6cb3e30cf3103c557f73e266 104 Pfam PF00085 Thioredoxin 4 102 7.0E-32 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 GTHT12_RS14000 8decc41d6cb3e30cf3103c557f73e266 104 ProSitePatterns PS00194 Thioredoxin family active site. 21 39 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 GTHT12_RS14000 8decc41d6cb3e30cf3103c557f73e266 104 PRINTS PR00421 Thioredoxin family signature 20 28 1.7E-9 T 06-07-2017 GTHT12_RS14000 8decc41d6cb3e30cf3103c557f73e266 104 PRINTS PR00421 Thioredoxin family signature 68 79 1.7E-9 T 06-07-2017 GTHT12_RS14000 8decc41d6cb3e30cf3103c557f73e266 104 PRINTS PR00421 Thioredoxin family signature 28 37 1.7E-9 T 06-07-2017 GTHT12_RS14000 8decc41d6cb3e30cf3103c557f73e266 104 PIRSF PIRSF000077 1 104 1.1E-42 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 GTHT12_RS14000 8decc41d6cb3e30cf3103c557f73e266 104 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 103 7.5E-40 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 GTHT12_RS14000 8decc41d6cb3e30cf3103c557f73e266 104 Gene3D G3DSA:3.40.30.10 3 103 4.8E-38 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS01225 bdfc0f6091a57452899d19f1bcc25b9e 243 SMART SM00646 64 174 4.0E-43 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 GTHT12_RS01225 bdfc0f6091a57452899d19f1bcc25b9e 243 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 4 174 5.2E-47 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 GTHT12_RS01225 bdfc0f6091a57452899d19f1bcc25b9e 243 SUPERFAMILY SSF53187 1 179 5.96E-53 T 06-07-2017 GTHT12_RS01225 bdfc0f6091a57452899d19f1bcc25b9e 243 Gene3D G3DSA:3.40.630.40 3 178 1.6E-54 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 GTHT12_RS03720 9ec2d3836e4d4718fd5f9570497fab4a 514 Pfam PF13193 AMP-binding enzyme C-terminal domain 425 499 2.7E-23 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain GTHT12_RS03720 9ec2d3836e4d4718fd5f9570497fab4a 514 Gene3D G3DSA:3.30.300.30 413 510 1.1E-35 T 06-07-2017 GTHT12_RS03720 9ec2d3836e4d4718fd5f9570497fab4a 514 Gene3D G3DSA:2.30.38.10 335 407 4.9E-31 T 06-07-2017 GTHT12_RS03720 9ec2d3836e4d4718fd5f9570497fab4a 514 ProSitePatterns PS00455 Putative AMP-binding domain signature. 171 182 - T 06-07-2017 IPR020845 AMP-binding, conserved site GTHT12_RS03720 9ec2d3836e4d4718fd5f9570497fab4a 514 SUPERFAMILY SSF56801 4 509 9.81E-176 T 06-07-2017 GTHT12_RS03720 9ec2d3836e4d4718fd5f9570497fab4a 514 Gene3D G3DSA:3.40.50.980 177 334 7.9E-56 T 06-07-2017 GTHT12_RS03720 9ec2d3836e4d4718fd5f9570497fab4a 514 Gene3D G3DSA:3.40.50.980 3 176 2.5E-42 T 06-07-2017 GTHT12_RS03720 9ec2d3836e4d4718fd5f9570497fab4a 514 Pfam PF00501 AMP-binding enzyme 9 416 3.8E-121 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GTHT12_RS03720 9ec2d3836e4d4718fd5f9570497fab4a 514 PRINTS PR00154 AMP-binding signature 178 186 6.0E-5 T 06-07-2017 IPR020459 AMP-binding GTHT12_RS03720 9ec2d3836e4d4718fd5f9570497fab4a 514 PRINTS PR00154 AMP-binding signature 166 177 6.0E-5 T 06-07-2017 IPR020459 AMP-binding GTHT12_RS10880 2a6232e476829ceb5da93ba355193c0b 239 Pfam PF12730 ABC-2 family transporter protein 5 185 4.9E-17 T 06-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 GTHT12_RS01585 c108cdf36a4decc2032690debd83af00 147 Gene3D G3DSA:2.60.40.790 3 144 3.8E-16 T 06-07-2017 IPR008978 HSP20-like chaperone GTHT12_RS01585 c108cdf36a4decc2032690debd83af00 147 Pfam PF00011 Hsp20/alpha crystallin family 45 142 1.5E-9 T 06-07-2017 IPR002068 Alpha crystallin/Hsp20 domain GTHT12_RS01585 c108cdf36a4decc2032690debd83af00 147 SUPERFAMILY SSF49764 8 142 3.49E-17 T 06-07-2017 IPR008978 HSP20-like chaperone GTHT12_RS08655 622728f8976022d64b88af01d02043ac 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 253 1.4E-71 T 06-07-2017 GTHT12_RS08655 622728f8976022d64b88af01d02043ac 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 9.1E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08655 622728f8976022d64b88af01d02043ac 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 9.1E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08655 622728f8976022d64b88af01d02043ac 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 9.1E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08655 622728f8976022d64b88af01d02043ac 256 Gene3D G3DSA:3.40.50.720 2 255 4.9E-92 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS08655 622728f8976022d64b88af01d02043ac 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 192 0.0012 T 06-07-2017 GTHT12_RS08655 622728f8976022d64b88af01d02043ac 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GTHT12_RS08655 622728f8976022d64b88af01d02043ac 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.3E-46 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08655 622728f8976022d64b88af01d02043ac 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 3.3E-46 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08655 622728f8976022d64b88af01d02043ac 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 3.3E-46 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08655 622728f8976022d64b88af01d02043ac 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 3.3E-46 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08655 622728f8976022d64b88af01d02043ac 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 3.3E-46 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08655 622728f8976022d64b88af01d02043ac 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.3E-46 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08655 622728f8976022d64b88af01d02043ac 256 SUPERFAMILY SSF51735 6 255 2.2E-87 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS04860 28a38bd9f717ea5011ecab0e46ce808d 290 SUPERFAMILY SSF110857 139 263 4.58E-23 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like GTHT12_RS04860 28a38bd9f717ea5011ecab0e46ce808d 290 Pfam PF13772 AIG2-like family 196 276 1.1E-13 T 06-07-2017 GTHT12_RS04860 28a38bd9f717ea5011ecab0e46ce808d 290 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 6 129 3.5E-24 T 06-07-2017 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like GTHT12_RS04860 28a38bd9f717ea5011ecab0e46ce808d 290 Gene3D G3DSA:3.10.490.10 135 288 1.3E-45 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like GTHT12_RS04860 28a38bd9f717ea5011ecab0e46ce808d 290 Gene3D G3DSA:3.10.490.10 4 134 4.7E-29 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like GTHT12_RS04860 28a38bd9f717ea5011ecab0e46ce808d 290 SUPERFAMILY SSF110857 3 135 1.12E-27 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like GTHT12_RS17275 196d91407a0e562decbb0a75bd739c24 362 Gene3D G3DSA:3.90.25.10 300 358 2.0E-51 T 06-07-2017 GTHT12_RS17275 196d91407a0e562decbb0a75bd739c24 362 Gene3D G3DSA:3.90.25.10 199 253 2.0E-51 T 06-07-2017 GTHT12_RS17275 196d91407a0e562decbb0a75bd739c24 362 Gene3D G3DSA:3.40.50.720 1 196 2.0E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS17275 196d91407a0e562decbb0a75bd739c24 362 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 2 353 56.252 T 06-07-2017 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 GTHT12_RS17275 196d91407a0e562decbb0a75bd739c24 362 SUPERFAMILY SSF51735 2 349 7.63E-85 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS17275 196d91407a0e562decbb0a75bd739c24 362 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 343 1.4E-155 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS17275 196d91407a0e562decbb0a75bd739c24 362 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 2 350 1.2E-175 T 06-07-2017 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 GTHT12_RS09515 dbd15a3a0dae81006a1e9c28c1348679 296 Pfam PF00248 Aldo/keto reductase family 15 286 3.2E-59 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain GTHT12_RS09515 dbd15a3a0dae81006a1e9c28c1348679 296 Gene3D G3DSA:3.20.20.100 4 287 3.8E-68 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain GTHT12_RS09515 dbd15a3a0dae81006a1e9c28c1348679 296 PRINTS PR00069 Aldo-keto reductase signature 42 66 3.3E-7 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GTHT12_RS09515 dbd15a3a0dae81006a1e9c28c1348679 296 PRINTS PR00069 Aldo-keto reductase signature 108 126 3.3E-7 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GTHT12_RS09515 dbd15a3a0dae81006a1e9c28c1348679 296 PRINTS PR00069 Aldo-keto reductase signature 139 156 3.3E-7 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GTHT12_RS09515 dbd15a3a0dae81006a1e9c28c1348679 296 SUPERFAMILY SSF51430 3 294 6.42E-76 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain GTHT12_RS12900 2a2783476fc515c151f93186d3551d6e 320 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 5 303 5.7E-91 T 06-07-2017 IPR011862 Phosphate binding protein GO:0006810 GTHT12_RS12900 2a2783476fc515c151f93186d3551d6e 320 Pfam PF12849 PBP superfamily domain 37 289 8.9E-33 T 06-07-2017 IPR024370 PBP domain GTHT12_RS12900 2a2783476fc515c151f93186d3551d6e 320 Gene3D G3DSA:3.40.190.10 45 187 4.9E-39 T 06-07-2017 GTHT12_RS12900 2a2783476fc515c151f93186d3551d6e 320 SUPERFAMILY SSF53850 44 317 3.89E-74 T 06-07-2017 GTHT12_RS00115 b2da32829c47f5c09e9e85ef7b1b66e3 108 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 7 101 23.895 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family GTHT12_RS00115 b2da32829c47f5c09e9e85ef7b1b66e3 108 SUPERFAMILY SSF82607 13 107 3.01E-35 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family GTHT12_RS00115 b2da32829c47f5c09e9e85ef7b1b66e3 108 PIRSF PIRSF004555 5 108 8.5E-41 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family GTHT12_RS00115 b2da32829c47f5c09e9e85ef7b1b66e3 108 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 2 107 2.1E-34 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family GTHT12_RS00115 b2da32829c47f5c09e9e85ef7b1b66e3 108 Pfam PF02575 YbaB/EbfC DNA-binding family 13 103 2.7E-36 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family GTHT12_RS00115 b2da32829c47f5c09e9e85ef7b1b66e3 108 Gene3D G3DSA:3.30.1310.10 4 108 2.5E-42 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family GTHT12_RS11935 1a553077d9f877e77cdafec14e3c9ed8 192 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 180 6.0E-94 T 06-07-2017 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 GTHT12_RS11935 1a553077d9f877e77cdafec14e3c9ed8 192 Pfam PF01923 Cobalamin adenosyltransferase 4 167 7.8E-60 T 06-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 GTHT12_RS11935 1a553077d9f877e77cdafec14e3c9ed8 192 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 178 6.1E-65 T 06-07-2017 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 GTHT12_RS11935 1a553077d9f877e77cdafec14e3c9ed8 192 Gene3D G3DSA:1.20.1200.10 13 182 4.2E-64 T 06-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 GTHT12_RS11935 1a553077d9f877e77cdafec14e3c9ed8 192 SUPERFAMILY SSF89028 1 179 7.85E-67 T 06-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 GTHT12_RS11165 1df3a114367d600a6007a35eb2023ee3 439 Gene3D G3DSA:3.40.190.10 179 371 5.6E-61 T 06-07-2017 GTHT12_RS11165 1df3a114367d600a6007a35eb2023ee3 439 Pfam PF01547 Bacterial extracellular solute-binding protein 59 352 6.7E-47 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 GTHT12_RS11165 1df3a114367d600a6007a35eb2023ee3 439 SUPERFAMILY SSF53850 52 416 1.68E-95 T 06-07-2017 GTHT12_RS11165 1df3a114367d600a6007a35eb2023ee3 439 Gene3D G3DSA:3.40.190.10 58 178 4.9E-6 T 06-07-2017 GTHT12_RS11750 3862f4e37c7f45061aa270661404dff5 198 PIRSF PIRSF036710 1 196 9.8E-39 T 06-07-2017 IPR014617 Predicted membrane protein, Bacillus YphA type GTHT12_RS16100 0e27bf8f060abbba0b9cab9d23542ade 111 Gene3D G3DSA:1.10.760.10 43 109 4.3E-24 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GTHT12_RS16100 0e27bf8f060abbba0b9cab9d23542ade 111 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 40 107 3.2E-14 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GTHT12_RS16100 0e27bf8f060abbba0b9cab9d23542ade 111 SUPERFAMILY SSF46626 1 109 2.82E-19 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GTHT12_RS16100 0e27bf8f060abbba0b9cab9d23542ade 111 PIRSF PIRSF000025 1 111 1.7E-37 T 06-07-2017 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 GTHT12_RS13580 18e4310c78550ccaf8d9e4ce62fd518a 367 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 20 366 2.2E-116 T 06-07-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 GTHT12_RS13580 18e4310c78550ccaf8d9e4ce62fd518a 367 SUPERFAMILY SSF142754 28 366 1.1E-99 T 06-07-2017 GTHT12_RS13580 18e4310c78550ccaf8d9e4ce62fd518a 367 Hamap MF_00569 Quinolinate synthase A [nadA]. 21 366 55.723 T 06-07-2017 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 GTHT12_RS13580 18e4310c78550ccaf8d9e4ce62fd518a 367 Pfam PF02445 Quinolinate synthetase A protein 30 365 2.0E-108 T 06-07-2017 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 GTHT12_RS03340 2ae8ea6ce9823b86dd864dba9cd70e00 348 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 49 304 4.0E-91 T 06-07-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 GTHT12_RS03340 2ae8ea6ce9823b86dd864dba9cd70e00 348 PIRSF PIRSF006470 22 348 2.1E-120 T 06-07-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 GTHT12_RS03340 2ae8ea6ce9823b86dd864dba9cd70e00 348 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 49 332 4.8E-104 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 GTHT12_RS08970 80c567f23acf5abd0c662570e7cf7526 163 SUPERFAMILY SSF55729 1 155 4.77E-30 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS08970 80c567f23acf5abd0c662570e7cf7526 163 Gene3D G3DSA:3.40.630.30 1 156 9.4E-36 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS08970 80c567f23acf5abd0c662570e7cf7526 163 Pfam PF13420 Acetyltransferase (GNAT) domain 3 151 1.5E-19 T 06-07-2017 GTHT12_RS07140 c32111abcf9d5fad15054f32da3e8dab 1081 Gene3D G3DSA:3.40.50.300 672 846 8.2E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07140 c32111abcf9d5fad15054f32da3e8dab 1081 SUPERFAMILY SSF52540 679 843 3.93E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07140 c32111abcf9d5fad15054f32da3e8dab 1081 SUPERFAMILY SSF52540 292 418 3.93E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07140 c32111abcf9d5fad15054f32da3e8dab 1081 Gene3D G3DSA:3.40.50.300 243 416 2.4E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07140 c32111abcf9d5fad15054f32da3e8dab 1081 SMART SM00487 242 433 2.4E-8 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain GTHT12_RS07140 c32111abcf9d5fad15054f32da3e8dab 1081 SMART SM00490 717 820 3.6E-10 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS07140 c32111abcf9d5fad15054f32da3e8dab 1081 Pfam PF04851 Type III restriction enzyme, res subunit 266 401 5.2E-5 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 GTHT12_RS07140 c32111abcf9d5fad15054f32da3e8dab 1081 Pfam PF00271 Helicase conserved C-terminal domain 696 820 2.7E-14 T 06-07-2017 IPR001650 Helicase, C-terminal GTHT12_RS12560 f000ba4d8f6382ceabcdf8c88b74c202 186 Pfam PF12685 SpoIIIAH-like protein 5 172 6.8E-29 T 06-07-2017 IPR024232 Stage III sporulation protein AH-like GTHT12_RS02935 96b1846fdd210a5c9bbca6895c8d495f 162 Pfam PF07849 Protein of unknown function (DUF1641) 122 156 3.1E-14 T 06-07-2017 IPR012440 Protein of unknown function DUF1641 GTHT12_RS10970 a47c7e5b2c0fc87a97030593b92c5a45 131 SUPERFAMILY SSF52821 7 106 1.21E-7 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS10970 a47c7e5b2c0fc87a97030593b92c5a45 131 Gene3D G3DSA:3.40.250.10 39 104 2.5E-4 T 06-07-2017 IPR001763 Rhodanese-like domain GTHT12_RS14105 f04135e10a201b0153d71062548bcf02 251 Pfam PF00588 SpoU rRNA Methylase family 107 245 8.4E-38 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 GTHT12_RS14105 f04135e10a201b0153d71062548bcf02 251 SMART SM00967 31 100 2.0E-13 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 GTHT12_RS14105 f04135e10a201b0153d71062548bcf02 251 SUPERFAMILY SSF55315 2 97 2.35E-25 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like GTHT12_RS14105 f04135e10a201b0153d71062548bcf02 251 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 31 97 3.4E-11 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 GTHT12_RS14105 f04135e10a201b0153d71062548bcf02 251 Gene3D G3DSA:3.40.1280.10 106 248 1.1E-48 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal GTHT12_RS14105 f04135e10a201b0153d71062548bcf02 251 Gene3D G3DSA:3.30.1330.30 3 96 8.2E-30 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like GTHT12_RS14105 f04135e10a201b0153d71062548bcf02 251 SUPERFAMILY SSF75217 99 249 1.64E-42 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases GTHT12_RS13715 d732670ce69a8b7f125f1c77ecb5c109 161 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 11 33 5.9E-7 T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site GTHT12_RS13715 d732670ce69a8b7f125f1c77ecb5c109 161 Gene3D G3DSA:3.30.700.10 14 119 1.5E-7 T 06-07-2017 GTHT12_RS13715 d732670ce69a8b7f125f1c77ecb5c109 161 SUPERFAMILY SSF54523 14 70 2.75E-12 T 06-07-2017 GTHT12_RS13715 d732670ce69a8b7f125f1c77ecb5c109 161 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 8 32 9.1E-7 T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site GTHT12_RS13715 d732670ce69a8b7f125f1c77ecb5c109 161 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 11 31 - T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site GTHT12_RS00830 1cd6271eb8fcd73b73a8007dd2870b65 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 06-07-2017 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00830 1cd6271eb8fcd73b73a8007dd2870b65 130 Gene3D G3DSA:3.30.230.10 5 130 5.0E-52 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup GTHT12_RS00830 1cd6271eb8fcd73b73a8007dd2870b65 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 35.345 T 06-07-2017 IPR023035 Ribosomal protein S9, bacterial/plastid GTHT12_RS00830 1cd6271eb8fcd73b73a8007dd2870b65 130 SUPERFAMILY SSF54211 5 130 2.5E-49 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold GTHT12_RS00830 1cd6271eb8fcd73b73a8007dd2870b65 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 5.3E-48 T 06-07-2017 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 GTHT12_RS05105 1e4c5c77c5087ba77117487dfea199ea 564 SUPERFAMILY SSF55486 36 559 7.42E-120 T 06-07-2017 GTHT12_RS05105 1e4c5c77c5087ba77117487dfea199ea 564 TIGRFAM TIGR02289 M3_not_pepF: oligoendopeptidase, M3 family 14 560 1.2E-217 T 06-07-2017 IPR011976 Peptidase M3B, oligoendopeptidase-related clade 2 GTHT12_RS05105 1e4c5c77c5087ba77117487dfea199ea 564 Pfam PF01432 Peptidase family M3 167 271 2.7E-6 T 06-07-2017 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 GTHT12_RS05105 1e4c5c77c5087ba77117487dfea199ea 564 Pfam PF01432 Peptidase family M3 310 543 6.6E-20 T 06-07-2017 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 GTHT12_RS05105 1e4c5c77c5087ba77117487dfea199ea 564 Gene3D G3DSA:1.10.1370.10 112 262 8.0E-7 T 06-07-2017 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 GTHT12_RS17405 58176f36d85eeb04beb920115bab0f95 251 Gene3D G3DSA:3.30.360.40 178 251 2.5E-29 T 06-07-2017 GTHT12_RS17405 58176f36d85eeb04beb920115bab0f95 251 Pfam PF08680 TATA-box binding 54 251 1.9E-58 T 06-07-2017 IPR014794 TATA-box binding GTHT12_RS17405 58176f36d85eeb04beb920115bab0f95 251 SUPERFAMILY SSF143842 37 249 4.84E-60 T 06-07-2017 IPR014794 TATA-box binding GTHT12_RS17405 58176f36d85eeb04beb920115bab0f95 251 Gene3D G3DSA:3.30.2030.10 37 175 3.5E-49 T 06-07-2017 GTHT12_RS16475 f085f1586caade75a878d788c182fd17 297 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 1.9E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS16475 f085f1586caade75a878d788c182fd17 297 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 1.9E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS16475 f085f1586caade75a878d788c182fd17 297 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 51 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site GTHT12_RS16475 f085f1586caade75a878d788c182fd17 297 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 52 3.5E-19 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS16475 f085f1586caade75a878d788c182fd17 297 Gene3D G3DSA:1.10.357.10 2 186 8.4E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 GTHT12_RS16475 f085f1586caade75a878d788c182fd17 297 SUPERFAMILY SSF46689 2 70 8.72E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 SUPERFAMILY SSF50249 191 275 5.97E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 SUPERFAMILY SSF50249 10 114 4.87E-19 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 PRINTS PR00681 Ribosomal protein S1 signature 156 176 7.1E-46 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 PRINTS PR00681 Ribosomal protein S1 signature 110 126 7.1E-46 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 PRINTS PR00681 Ribosomal protein S1 signature 213 234 7.1E-46 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 PRINTS PR00681 Ribosomal protein S1 signature 330 348 7.1E-46 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 PRINTS PR00681 Ribosomal protein S1 signature 127 144 7.1E-46 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 PRINTS PR00681 Ribosomal protein S1 signature 291 310 7.1E-46 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 PRINTS PR00681 Ribosomal protein S1 signature 15 33 7.1E-46 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 SUPERFAMILY SSF50249 256 360 7.55E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 Pfam PF00575 S1 RNA binding domain 190 261 1.7E-21 T 06-07-2017 IPR003029 S1 domain GO:0003676 GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 Pfam PF00575 S1 RNA binding domain 274 347 2.2E-23 T 06-07-2017 IPR003029 S1 domain GO:0003676 GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 Pfam PF00575 S1 RNA binding domain 14 77 1.9E-12 T 06-07-2017 IPR003029 S1 domain GO:0003676 GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 Pfam PF00575 S1 RNA binding domain 103 172 3.9E-13 T 06-07-2017 IPR003029 S1 domain GO:0003676 GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 SUPERFAMILY SSF50249 92 176 1.34E-15 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 Gene3D G3DSA:2.40.50.140 16 102 2.6E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 Gene3D G3DSA:2.40.50.140 193 273 2.2E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 Gene3D G3DSA:2.40.50.140 274 348 5.8E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 Gene3D G3DSA:2.40.50.140 103 173 6.9E-17 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 SMART SM00316 191 261 1.7E-28 T 06-07-2017 IPR022967 RNA-binding domain, S1 GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 SMART SM00316 13 89 6.8E-15 T 06-07-2017 IPR022967 RNA-binding domain, S1 GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 SMART SM00316 276 347 2.3E-28 T 06-07-2017 IPR022967 RNA-binding domain, S1 GTHT12_RS11785 868d3b04add219138079fb0d0ca75c0b 387 SMART SM00316 105 172 5.3E-9 T 06-07-2017 IPR022967 RNA-binding domain, S1 GTHT12_RS02495 c3416432a57547964fedaae22a481304 377 Pfam PF07690 Major Facilitator Superfamily 9 222 1.4E-22 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS02495 c3416432a57547964fedaae22a481304 377 ProSitePatterns PS00216 Sugar transport proteins signature 1. 251 267 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 GTHT12_RS02495 c3416432a57547964fedaae22a481304 377 PRINTS PR01035 Tetracycline resistance protein signature 251 271 1.4E-6 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS02495 c3416432a57547964fedaae22a481304 377 PRINTS PR01035 Tetracycline resistance protein signature 12 28 1.4E-6 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS02495 c3416432a57547964fedaae22a481304 377 PRINTS PR01035 Tetracycline resistance protein signature 127 149 1.4E-6 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS02495 c3416432a57547964fedaae22a481304 377 SUPERFAMILY SSF103473 3 373 6.93E-51 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS02495 c3416432a57547964fedaae22a481304 377 Gene3D G3DSA:1.20.1250.20 3 180 1.2E-23 T 06-07-2017 GTHT12_RS02495 c3416432a57547964fedaae22a481304 377 Gene3D G3DSA:1.20.1250.20 195 370 1.3E-22 T 06-07-2017 GTHT12_RS17310 5c62e6ad134902c7a7526447efc16acf 232 Gene3D G3DSA:3.40.50.300 49 223 6.0E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17310 5c62e6ad134902c7a7526447efc16acf 232 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 50 222 6.9E-21 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain GTHT12_RS17310 5c62e6ad134902c7a7526447efc16acf 232 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 28 231 1.1E-71 T 06-07-2017 IPR005702 Exopolysaccharide synthesis protein GO:0045226 GTHT12_RS17310 5c62e6ad134902c7a7526447efc16acf 232 SUPERFAMILY SSF52540 48 227 1.58E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS03665 0ee4b2d9ee2f930e453edc922899f30a 144 PRINTS PR00332 Histidine triad family signature 30 48 2.1E-18 T 06-07-2017 IPR001310 Histidine triad (HIT) protein GTHT12_RS03665 0ee4b2d9ee2f930e453edc922899f30a 144 PRINTS PR00332 Histidine triad family signature 9 25 2.1E-18 T 06-07-2017 IPR001310 Histidine triad (HIT) protein GTHT12_RS03665 0ee4b2d9ee2f930e453edc922899f30a 144 PRINTS PR00332 Histidine triad family signature 97 107 2.1E-18 T 06-07-2017 IPR001310 Histidine triad (HIT) protein GTHT12_RS03665 0ee4b2d9ee2f930e453edc922899f30a 144 SUPERFAMILY SSF54197 6 143 7.05E-48 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 GTHT12_RS03665 0ee4b2d9ee2f930e453edc922899f30a 144 ProSitePatterns PS00892 HIT domain signature. 90 108 - T 06-07-2017 IPR019808 Histidine triad, conserved site GTHT12_RS03665 0ee4b2d9ee2f930e453edc922899f30a 144 Gene3D G3DSA:3.30.428.10 7 143 2.6E-45 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 GTHT12_RS03665 0ee4b2d9ee2f930e453edc922899f30a 144 Pfam PF01230 HIT domain 16 110 3.5E-28 T 06-07-2017 IPR001310 Histidine triad (HIT) protein GTHT12_RS03850 c8b6a5a462f51fbaf325693c4cc5d61f 389 Pfam PF04235 Protein of unknown function (DUF418) 224 378 3.8E-44 T 06-07-2017 IPR007349 Domain of unknown function DUF418 GTHT12_RS10635 5d2f779067ee61b112c35ac82c7f7194 311 SUPERFAMILY SSF47240 27 242 3.08E-50 T 06-07-2017 IPR009078 Ferritin-like superfamily GTHT12_RS10635 5d2f779067ee61b112c35ac82c7f7194 311 Pfam PF05138 Phenylacetic acid catabolic protein 18 251 9.7E-58 T 06-07-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 GTHT12_RS10635 5d2f779067ee61b112c35ac82c7f7194 311 Gene3D G3DSA:1.20.1260.10 19 243 9.3E-45 T 06-07-2017 IPR012347 Ferritin-related GTHT12_RS15265 7832871b6bdc5230f4579062f3496a87 65 Pfam PF08141 Small acid-soluble spore protein H family 1 59 1.7E-23 T 06-07-2017 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 GTHT12_RS15265 7832871b6bdc5230f4579062f3496a87 65 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 1 59 4.2E-16 T 06-07-2017 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 GTHT12_RS15265 7832871b6bdc5230f4579062f3496a87 65 ProDom PD052450 H SPORE ACID-SOLUBLE SMALL SASP SPORULATION SMALL PROTEIN-RELATED SOLUBLE RBL04815 1 59 3.0E-6 T 06-07-2017 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 GTHT12_RS15265 7832871b6bdc5230f4579062f3496a87 65 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 60 17.883 T 06-07-2017 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 GTHT12_RS06880 bc4200657714602db27498ffddf22aae 101 SMART SM00257 36 87 0.0012 T 06-07-2017 IPR018392 LysM domain GTHT12_RS06880 bc4200657714602db27498ffddf22aae 101 Hamap MF_02014 Cell division suppressor protein YneA [yneA]. 3 101 24.789 T 06-07-2017 IPR022887 Cell division suppressor protein, YneA GTHT12_RS06880 bc4200657714602db27498ffddf22aae 101 Gene3D G3DSA:3.10.350.10 38 88 7.0E-11 T 06-07-2017 IPR018392 LysM domain GTHT12_RS06880 bc4200657714602db27498ffddf22aae 101 SUPERFAMILY SSF54106 34 87 1.01E-5 T 06-07-2017 IPR018392 LysM domain GTHT12_RS06880 bc4200657714602db27498ffddf22aae 101 Pfam PF01476 LysM domain 38 87 2.3E-9 T 06-07-2017 IPR018392 LysM domain GTHT12_RS02475 50ad3d4c73e7c39bd6a2c3f6c4656a03 74 Hamap MF_00829 UPF0435 protein . 6 73 21.045 T 06-07-2017 IPR009507 Protein of unknown function UPF0435 GTHT12_RS02475 50ad3d4c73e7c39bd6a2c3f6c4656a03 74 Pfam PF06569 Protein of unknown function (DUF1128) 3 73 2.0E-34 T 06-07-2017 IPR009507 Protein of unknown function UPF0435 GTHT12_RS08320 8f7addae7043343e1fd4807370440dad 365 Pfam PF03845 Spore germination protein 6 318 5.3E-30 T 06-07-2017 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 GTHT12_RS08320 8f7addae7043343e1fd4807370440dad 365 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 6 359 8.4E-61 T 06-07-2017 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 GTHT12_RS13635 53f6b18153ca2a723b6bbc362a4a0bed 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 27.897 T 06-07-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS13635 53f6b18153ca2a723b6bbc362a4a0bed 102 SUPERFAMILY SSF141091 1 101 6.02E-41 T 06-07-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS13635 53f6b18153ca2a723b6bbc362a4a0bed 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 1.8E-42 T 06-07-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS13635 53f6b18153ca2a723b6bbc362a4a0bed 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 7.4E-41 T 06-07-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS13635 53f6b18153ca2a723b6bbc362a4a0bed 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 06-07-2017 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS10170 2555068e048f237c3bd4d232d3723a0e 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 248 4.4E-60 T 06-07-2017 GTHT12_RS10170 2555068e048f237c3bd4d232d3723a0e 251 Gene3D G3DSA:3.40.50.720 5 249 1.7E-83 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS10170 2555068e048f237c3bd4d232d3723a0e 251 SUPERFAMILY SSF51735 5 249 5.52E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS10170 2555068e048f237c3bd4d232d3723a0e 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GTHT12_RS10170 2555068e048f237c3bd4d232d3723a0e 251 TIGRFAM TIGR01832 kduD: 2-deoxy-D-gluconate 3-dehydrogenase 5 250 1.5E-121 T 06-07-2017 IPR011286 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase GO:0008678|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.12+1.1.1.127|MetaCyc: PWY-5515|MetaCyc: PWY-6507|MetaCyc: PWY-7562 GTHT12_RS10170 2555068e048f237c3bd4d232d3723a0e 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 4.7E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS10170 2555068e048f237c3bd4d232d3723a0e 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 4.7E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS10170 2555068e048f237c3bd4d232d3723a0e 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 4.7E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS10170 2555068e048f237c3bd4d232d3723a0e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 5.3E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS10170 2555068e048f237c3bd4d232d3723a0e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 5.3E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS10170 2555068e048f237c3bd4d232d3723a0e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 5.3E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS10170 2555068e048f237c3bd4d232d3723a0e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 5.3E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS10170 2555068e048f237c3bd4d232d3723a0e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 5.3E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS10170 2555068e048f237c3bd4d232d3723a0e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 5.3E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS02215 e0a0a9edc1c79c2ff5e0441cec46d6d0 396 SUPERFAMILY SSF53756 3 379 4.45E-44 T 06-07-2017 GTHT12_RS02215 e0a0a9edc1c79c2ff5e0441cec46d6d0 396 Pfam PF13439 Glycosyltransferase Family 4 37 170 1.1E-11 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 GTHT12_RS02215 e0a0a9edc1c79c2ff5e0441cec46d6d0 396 Gene3D G3DSA:3.40.50.2000 176 285 2.4E-7 T 06-07-2017 GTHT12_RS02215 e0a0a9edc1c79c2ff5e0441cec46d6d0 396 Pfam PF13692 Glycosyl transferases group 1 193 345 3.9E-12 T 06-07-2017 GTHT12_RS14240 a354a0dabb1f020963c32b911086d361 151 Pfam PF04284 Protein of unknown function (DUF441) 6 145 2.7E-46 T 06-07-2017 IPR007382 Uncharacterised protein family UPF0756, transmembrame GTHT12_RS14240 a354a0dabb1f020963c32b911086d361 151 ProDom PD021096 MEMBRANE YEAL PRECURSOR SIGNAL PROTEIN TRANSMEMBRANE YTWI HI1074 INTEGRAL SPANNING 20 130 9.0E-37 T 06-07-2017 IPR007382 Uncharacterised protein family UPF0756, transmembrame GTHT12_RS14240 a354a0dabb1f020963c32b911086d361 151 Hamap MF_01874 UPF0756 membrane protein YeaL [yeaL]. 2 148 18.885 T 06-07-2017 IPR007382 Uncharacterised protein family UPF0756, transmembrame GTHT12_RS18075 a6dea71dcfeae6b9499cd28f478c62fa 86 Gene3D G3DSA:3.90.79.10 22 86 5.7E-20 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 GTHT12_RS18075 a6dea71dcfeae6b9499cd28f478c62fa 86 SUPERFAMILY SSF55811 17 86 1.29E-19 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 GTHT12_RS18075 a6dea71dcfeae6b9499cd28f478c62fa 86 ProSitePatterns PS00893 Nudix box signature. 63 84 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 GTHT12_RS18075 a6dea71dcfeae6b9499cd28f478c62fa 86 Pfam PF00293 NUDIX domain 33 85 4.3E-13 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 GTHT12_RS18075 a6dea71dcfeae6b9499cd28f478c62fa 86 PRINTS PR00502 NUDIX hydrolase family signature 72 86 2.7E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 GTHT12_RS18075 a6dea71dcfeae6b9499cd28f478c62fa 86 PRINTS PR00502 NUDIX hydrolase family signature 58 72 2.7E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 GTHT12_RS13890 32aa449e62b92e1f9cb552d3f22119a4 577 Gene3D G3DSA:3.40.50.970 360 560 2.5E-80 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS13890 32aa449e62b92e1f9cb552d3f22119a4 577 Gene3D G3DSA:3.40.50.970 15 189 4.3E-73 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS13890 32aa449e62b92e1f9cb552d3f22119a4 577 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 397 544 2.3E-53 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 GTHT12_RS13890 32aa449e62b92e1f9cb552d3f22119a4 577 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 16 569 7.0E-267 T 06-07-2017 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 GTHT12_RS13890 32aa449e62b92e1f9cb552d3f22119a4 577 SUPERFAMILY SSF52467 197 365 5.24E-63 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS13890 32aa449e62b92e1f9cb552d3f22119a4 577 Gene3D G3DSA:3.40.50.1220 198 359 6.2E-67 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain GTHT12_RS13890 32aa449e62b92e1f9cb552d3f22119a4 577 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 205 340 1.7E-47 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 GTHT12_RS13890 32aa449e62b92e1f9cb552d3f22119a4 577 SUPERFAMILY SSF52518 375 569 2.95E-71 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS13890 32aa449e62b92e1f9cb552d3f22119a4 577 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 16 177 3.9E-54 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 GTHT12_RS13890 32aa449e62b92e1f9cb552d3f22119a4 577 SUPERFAMILY SSF52518 12 192 9.68E-60 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS00695 b3c371fc491fdd70dd33866792b423d9 141 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 8.2E-53 T 06-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00695 b3c371fc491fdd70dd33866792b423d9 141 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 41.945 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00695 b3c371fc491fdd70dd33866792b423d9 141 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.9E-64 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00695 b3c371fc491fdd70dd33866792b423d9 141 PRINTS PR00060 Ribosomal protein L16 signature 88 117 3.0E-41 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00695 b3c371fc491fdd70dd33866792b423d9 141 PRINTS PR00060 Ribosomal protein L16 signature 24 36 3.0E-41 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00695 b3c371fc491fdd70dd33866792b423d9 141 PRINTS PR00060 Ribosomal protein L16 signature 42 53 3.0E-41 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00695 b3c371fc491fdd70dd33866792b423d9 141 PRINTS PR00060 Ribosomal protein L16 signature 58 87 3.0E-41 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00695 b3c371fc491fdd70dd33866792b423d9 141 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 06-07-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00695 b3c371fc491fdd70dd33866792b423d9 141 Gene3D G3DSA:3.90.1170.10 23 136 1.7E-57 T 06-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00695 b3c371fc491fdd70dd33866792b423d9 141 SUPERFAMILY SSF54686 1 136 3.53E-60 T 06-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00695 b3c371fc491fdd70dd33866792b423d9 141 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 06-07-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS16940 31754313467f39914737b354d73f00b3 387 Gene3D G3DSA:3.40.50.2000 207 366 1.3E-64 T 06-07-2017 GTHT12_RS16940 31754313467f39914737b354d73f00b3 387 SUPERFAMILY SSF53756 5 371 4.13E-136 T 06-07-2017 GTHT12_RS16940 31754313467f39914737b354d73f00b3 387 Gene3D G3DSA:3.40.50.2000 4 206 2.8E-84 T 06-07-2017 GTHT12_RS16940 31754313467f39914737b354d73f00b3 387 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 5 368 3.9E-168 T 06-07-2017 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 GTHT12_RS16940 31754313467f39914737b354d73f00b3 387 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 27 365 2.9E-119 T 06-07-2017 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 GTHT12_RS01910 e787cae00a5565155075c1703734f63f 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 245 1.5E-63 T 06-07-2017 GTHT12_RS01910 e787cae00a5565155075c1703734f63f 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 6.2E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01910 e787cae00a5565155075c1703734f63f 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 6.2E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01910 e787cae00a5565155075c1703734f63f 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.2E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01910 e787cae00a5565155075c1703734f63f 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 6.2E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01910 e787cae00a5565155075c1703734f63f 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 6.2E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01910 e787cae00a5565155075c1703734f63f 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 6.2E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01910 e787cae00a5565155075c1703734f63f 248 Gene3D G3DSA:3.40.50.720 2 247 1.6E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS01910 e787cae00a5565155075c1703734f63f 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 6.1E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01910 e787cae00a5565155075c1703734f63f 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 6.1E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01910 e787cae00a5565155075c1703734f63f 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 6.1E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS01910 e787cae00a5565155075c1703734f63f 248 SUPERFAMILY SSF51735 5 246 1.9E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS17580 29b3f3dc5c374a1e7bcf56bf274fb8c8 207 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 174 187 - T 06-07-2017 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 GTHT12_RS17580 29b3f3dc5c374a1e7bcf56bf274fb8c8 207 SUPERFAMILY SSF57716 142 198 7.6E-17 T 06-07-2017 GTHT12_RS17580 29b3f3dc5c374a1e7bcf56bf274fb8c8 207 Pfam PF00265 Thymidine kinase 8 187 1.4E-57 T 06-07-2017 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 GTHT12_RS17580 29b3f3dc5c374a1e7bcf56bf274fb8c8 207 PIRSF PIRSF035805 5 200 1.2E-66 T 06-07-2017 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 GTHT12_RS17580 29b3f3dc5c374a1e7bcf56bf274fb8c8 207 SUPERFAMILY SSF52540 8 142 8.36E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17580 29b3f3dc5c374a1e7bcf56bf274fb8c8 207 Hamap MF_00124 Thymidine kinase [tdk]. 7 190 38.597 T 06-07-2017 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-73614 GTHT12_RS17580 29b3f3dc5c374a1e7bcf56bf274fb8c8 207 Gene3D G3DSA:3.30.60.20 142 187 2.8E-14 T 06-07-2017 GTHT12_RS03395 92464805f82a025a38ad20606e22733c 85 Pfam PF14148 YhdB-like protein 2 70 4.2E-39 T 06-07-2017 IPR025431 YhdB-like protein GTHT12_RS06665 e0a1fcfab2ed1481a707751e3556dd08 348 Pfam PF02653 Branched-chain amino acid transport system / permease component 52 330 6.0E-47 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 GTHT12_RS15795 dc2157e6ebc50b02de25ae72b1a4f230 130 SUPERFAMILY SSF55331 2 127 5.68E-41 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily GTHT12_RS15795 dc2157e6ebc50b02de25ae72b1a4f230 130 Gene3D G3DSA:3.30.429.10 2 127 3.7E-49 T 06-07-2017 GTHT12_RS15795 dc2157e6ebc50b02de25ae72b1a4f230 130 Pfam PF02962 5-carboxymethyl-2-hydroxymuconate isomerase 2 126 8.6E-46 T 06-07-2017 IPR004220 5-carboxymethyl-2-hydroxymuconate isomerase GO:0008704|GO:0019439 KEGG: 00350+5.3.3.10 GTHT12_RS01310 2357cfa69098007516725ffd972f8d15 337 SUPERFAMILY SSF89392 29 203 2.63E-18 T 06-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX GTHT12_RS01310 2357cfa69098007516725ffd972f8d15 337 Gene3D G3DSA:2.50.20.10 23 205 3.1E-18 T 06-07-2017 GTHT12_RS09400 bb5ca54265286fea90c310e673e5a3c6 256 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 4 236 3.6E-96 T 06-07-2017 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 GTHT12_RS09400 bb5ca54265286fea90c310e673e5a3c6 256 Gene3D G3DSA:3.30.950.10 120 245 2.4E-48 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS09400 bb5ca54265286fea90c310e673e5a3c6 256 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 84 117 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 GTHT12_RS09400 bb5ca54265286fea90c310e673e5a3c6 256 Gene3D G3DSA:3.40.1010.10 4 119 1.2E-44 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS09400 bb5ca54265286fea90c310e673e5a3c6 256 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 212 5.0E-49 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS09400 bb5ca54265286fea90c310e673e5a3c6 256 SUPERFAMILY SSF53790 2 244 4.58E-80 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS04250 e3ea065ea619c7937bddd3a84b1d0561 706 Gene3D G3DSA:1.20.1640.10 145 349 4.0E-32 T 06-07-2017 GTHT12_RS04250 e3ea065ea619c7937bddd3a84b1d0561 706 Gene3D G3DSA:1.20.1640.10 489 699 4.1E-22 T 06-07-2017 GTHT12_RS04250 e3ea065ea619c7937bddd3a84b1d0561 706 Pfam PF03176 MMPL family 408 692 5.6E-45 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 GTHT12_RS04250 e3ea065ea619c7937bddd3a84b1d0561 706 Pfam PF03176 MMPL family 50 377 9.4E-64 T 06-07-2017 IPR004869 Membrane transport protein, MMPL domain GO:0016020 GTHT12_RS04250 e3ea065ea619c7937bddd3a84b1d0561 706 SUPERFAMILY SSF82866 470 696 3.92E-24 T 06-07-2017 GTHT12_RS04250 e3ea065ea619c7937bddd3a84b1d0561 706 SUPERFAMILY SSF82866 154 348 9.94E-33 T 06-07-2017 GTHT12_RS16010 e439e8be662b0dcf27d8c5fea832396c 165 SUPERFAMILY SSF51161 9 160 4.71E-38 T 06-07-2017 IPR011004 Trimeric LpxA-like GTHT12_RS16010 e439e8be662b0dcf27d8c5fea832396c 165 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 115 143 - T 06-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 GTHT12_RS16010 e439e8be662b0dcf27d8c5fea832396c 165 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 107 140 5.0E-11 T 06-07-2017 IPR001451 Hexapeptide repeat GTHT12_RS16010 e439e8be662b0dcf27d8c5fea832396c 165 Gene3D G3DSA:2.160.10.10 55 162 9.2E-34 T 06-07-2017 GTHT12_RS16010 e439e8be662b0dcf27d8c5fea832396c 165 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 72 92 0.0013 T 06-07-2017 IPR001451 Hexapeptide repeat GTHT12_RS04260 6cf286ecf17a4082fee57763996becb9 246 Gene3D G3DSA:3.40.50.1820 168 241 1.2E-7 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS04260 6cf286ecf17a4082fee57763996becb9 246 Gene3D G3DSA:3.40.50.1820 50 136 1.2E-7 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS04260 6cf286ecf17a4082fee57763996becb9 246 SUPERFAMILY SSF53474 10 238 2.57E-12 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS05535 d779f503453e7447ce8060067dee69a4 187 SUPERFAMILY SSF52833 5 182 5.38E-61 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS05535 d779f503453e7447ce8060067dee69a4 187 Pfam PF00578 AhpC/TSA family 6 141 5.8E-39 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GTHT12_RS05535 d779f503453e7447ce8060067dee69a4 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 164 180 1.6E-4 T 06-07-2017 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GTHT12_RS05535 d779f503453e7447ce8060067dee69a4 187 PIRSF PIRSF000239 1 187 5.0E-62 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GTHT12_RS05535 d779f503453e7447ce8060067dee69a4 187 Gene3D G3DSA:3.40.30.10 6 183 4.1E-69 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS05370 54cb5036638fcd02f0d15b2b8309a60f 183 Pfam PF06866 Protein of unknown function (DUF1256) 5 162 5.3E-35 T 06-07-2017 IPR009665 Protein of unknown function DUF1256 GTHT12_RS05370 54cb5036638fcd02f0d15b2b8309a60f 183 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 28 164 7.7E-33 T 06-07-2017 IPR009665 Protein of unknown function DUF1256 GTHT12_RS05370 54cb5036638fcd02f0d15b2b8309a60f 183 SUPERFAMILY SSF53163 3 172 6.8E-30 T 06-07-2017 IPR023430 Peptidase HybD-like domain GTHT12_RS16200 162799f8ee54adf4e211eb53b4f898c0 361 Gene3D G3DSA:1.20.1330.10 250 349 1.8E-63 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 GTHT12_RS16200 162799f8ee54adf4e211eb53b4f898c0 361 Gene3D G3DSA:1.20.1330.10 52 138 1.8E-63 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 GTHT12_RS16200 162799f8ee54adf4e211eb53b4f898c0 361 SUPERFAMILY SSF64518 1 358 4.05E-83 T 06-07-2017 GTHT12_RS16200 162799f8ee54adf4e211eb53b4f898c0 361 PRINTS PR00207 Flagellin signature 35 52 9.7E-26 T 06-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 GTHT12_RS16200 162799f8ee54adf4e211eb53b4f898c0 361 PRINTS PR00207 Flagellin signature 74 93 9.7E-26 T 06-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 GTHT12_RS16200 162799f8ee54adf4e211eb53b4f898c0 361 PRINTS PR00207 Flagellin signature 109 132 9.7E-26 T 06-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 GTHT12_RS16200 162799f8ee54adf4e211eb53b4f898c0 361 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 139 1.8E-45 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 GTHT12_RS16200 162799f8ee54adf4e211eb53b4f898c0 361 Pfam PF00700 Bacterial flagellin C-terminal helical region 307 360 6.0E-17 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 GTHT12_RS18625 762a90e9244b8feb105e8760bc7d7df6 70 Gene3D G3DSA:3.40.50.150 3 69 2.5E-10 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS18625 762a90e9244b8feb105e8760bc7d7df6 70 Pfam PF00145 C-5 cytosine-specific DNA methylase 3 57 2.9E-8 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS18625 762a90e9244b8feb105e8760bc7d7df6 70 SUPERFAMILY SSF53335 3 69 2.11E-9 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS06260 6cce94a1c25ac74872460cc54dd2784c 259 Pfam PF01351 Ribonuclease HII 75 250 4.5E-38 T 06-07-2017 IPR024567 Ribonuclease HII/HIII domain GTHT12_RS06260 6cce94a1c25ac74872460cc54dd2784c 259 Hamap MF_00052_B Ribonuclease HII [rnhB]. 73 251 36.101 T 06-07-2017 IPR022898 Ribonuclease HII GO:0004523 GTHT12_RS06260 6cce94a1c25ac74872460cc54dd2784c 259 Gene3D G3DSA:3.30.420.10 73 212 5.1E-49 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS06260 6cce94a1c25ac74872460cc54dd2784c 259 SUPERFAMILY SSF53098 62 256 4.86E-71 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS03865 818d6e0aec9ea13d59bc492668014c2a 117 ProDom PD067392 MEMBRANE UPF0344 TRANSMEMBRANE MW0851 BCE1257 SIMILAR YISL SAR0931 BCE33L1051 BT9727_1053 1 103 2.0E-34 T 06-07-2017 IPR010899 Protein of unknown function UPF0344 GTHT12_RS03865 818d6e0aec9ea13d59bc492668014c2a 117 Pfam PF07457 Protein of unknown function (DUF1516) 2 107 2.5E-31 T 06-07-2017 IPR010899 Protein of unknown function UPF0344 GTHT12_RS03865 818d6e0aec9ea13d59bc492668014c2a 117 Hamap MF_01536 UPF0344 protein . 1 117 16.363 T 06-07-2017 IPR010899 Protein of unknown function UPF0344 GTHT12_RS07685 78a7f4aee092202cd64d7a4c1739e9e3 282 PIRSF PIRSF002854 1 276 5.7E-84 T 06-07-2017 IPR004872 Lipoprotein NlpA family GTHT12_RS07685 78a7f4aee092202cd64d7a4c1739e9e3 282 Pfam PF03180 NLPA lipoprotein 40 276 3.9E-78 T 06-07-2017 IPR004872 Lipoprotein NlpA family GTHT12_RS07685 78a7f4aee092202cd64d7a4c1739e9e3 282 SUPERFAMILY SSF53850 39 278 8.03E-73 T 06-07-2017 GTHT12_RS07685 78a7f4aee092202cd64d7a4c1739e9e3 282 Gene3D G3DSA:3.40.190.10 36 168 2.8E-51 T 06-07-2017 GTHT12_RS02790 44da1f58d80b4de8d10cc5a59e3064a8 243 PIRSF PIRSF031509 5 243 2.7E-63 T 06-07-2017 IPR016975 Cell wall-active antibiotic response protein GO:0016021 GTHT12_RS02790 44da1f58d80b4de8d10cc5a59e3064a8 243 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 127 240 1.1E-37 T 06-07-2017 IPR024425 Cell wall-active antibiotics response 4TMS YvqF GTHT12_RS17295 3d9aa3dfe8031ac27d3f6000dfcb32d0 255 SUPERFAMILY SSF89550 1 201 1.06E-16 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 GTHT12_RS17295 3d9aa3dfe8031ac27d3f6000dfcb32d0 255 PIRSF PIRSF016557 1 255 8.5E-109 T 06-07-2017 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 GTHT12_RS00210 b6d8572425beac7400008643598de11d 256 SUPERFAMILY SSF51556 2 254 7.0E-98 T 06-07-2017 IPR032466 Metal-dependent hydrolase GTHT12_RS00210 b6d8572425beac7400008643598de11d 256 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 06-07-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 GTHT12_RS00210 b6d8572425beac7400008643598de11d 256 PIRSF PIRSF005902 1 256 1.7E-90 T 06-07-2017 IPR001130 TatD family GO:0016788 GTHT12_RS00210 b6d8572425beac7400008643598de11d 256 Pfam PF01026 TatD related DNase 3 252 4.0E-88 T 06-07-2017 IPR001130 TatD family GO:0016788 GTHT12_RS00210 b6d8572425beac7400008643598de11d 256 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 189 205 - T 06-07-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 GTHT12_RS00210 b6d8572425beac7400008643598de11d 256 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 253 6.8E-101 T 06-07-2017 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 GTHT12_RS00210 b6d8572425beac7400008643598de11d 256 Gene3D G3DSA:3.20.20.140 1 255 2.0E-101 T 06-07-2017 GTHT12_RS13300 712a7f423621d924518c44561f7c51d7 309 SUPERFAMILY SSF53686 2 301 3.8E-92 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GTHT12_RS13300 712a7f423621d924518c44561f7c51d7 309 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 292 2.0E-65 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GTHT12_RS13300 712a7f423621d924518c44561f7c51d7 309 Gene3D G3DSA:3.40.50.1100 150 304 7.3E-72 T 06-07-2017 GTHT12_RS13300 712a7f423621d924518c44561f7c51d7 309 Gene3D G3DSA:3.40.50.1100 1 42 7.3E-72 T 06-07-2017 GTHT12_RS13300 712a7f423621d924518c44561f7c51d7 309 Gene3D G3DSA:3.40.50.1100 43 144 2.7E-34 T 06-07-2017 GTHT12_RS07025 b535070694c1a1ecb17d90d98a54f151 66 SMART SM00357 3 66 5.0E-31 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 GTHT12_RS07025 b535070694c1a1ecb17d90d98a54f151 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 06-07-2017 IPR019844 Cold-shock conserved site GTHT12_RS07025 b535070694c1a1ecb17d90d98a54f151 66 SUPERFAMILY SSF50249 1 65 3.6E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS07025 b535070694c1a1ecb17d90d98a54f151 66 Gene3D G3DSA:2.40.50.140 1 64 2.9E-31 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS07025 b535070694c1a1ecb17d90d98a54f151 66 PRINTS PR00050 Cold shock protein signature 24 33 1.5E-18 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 GTHT12_RS07025 b535070694c1a1ecb17d90d98a54f151 66 PRINTS PR00050 Cold shock protein signature 4 19 1.5E-18 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 GTHT12_RS07025 b535070694c1a1ecb17d90d98a54f151 66 PRINTS PR00050 Cold shock protein signature 39 57 1.5E-18 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 GTHT12_RS07025 b535070694c1a1ecb17d90d98a54f151 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.6E-30 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 GTHT12_RS07025 b535070694c1a1ecb17d90d98a54f151 66 PIRSF PIRSF002599 1 66 2.6E-24 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 GTHT12_RS12240 fb3c5bcaa5918de65cd6cde79ee4cbd0 184 SUPERFAMILY SSF55811 7 179 6.23E-52 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 GTHT12_RS12240 fb3c5bcaa5918de65cd6cde79ee4cbd0 184 Gene3D G3DSA:3.90.79.10 6 179 2.0E-60 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 GTHT12_RS12240 fb3c5bcaa5918de65cd6cde79ee4cbd0 184 Pfam PF00293 NUDIX domain 42 158 2.4E-17 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 GTHT12_RS12240 fb3c5bcaa5918de65cd6cde79ee4cbd0 184 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 7 177 1.8E-24 T 06-07-2017 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 Reactome: R-HSA-480985 GTHT12_RS02000 36078cad4e9dc30bd24c1a19554729f6 186 Pfam PF08006 Protein of unknown function (DUF1700) 1 181 4.0E-55 T 06-07-2017 IPR012963 Protein of unknown function DUF1700 GTHT12_RS01150 6e1cb0da604b17cafe2439ff5c0d8a99 202 Pfam PF09335 SNARE associated Golgi protein 30 160 1.3E-21 T 06-07-2017 IPR032816 SNARE associated Golgi protein GTHT12_RS12310 81367c5c555b77fdeefc44233dd1cc72 205 Pfam PF04199 Putative cyclase 4 146 4.0E-27 T 06-07-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 GTHT12_RS12310 81367c5c555b77fdeefc44233dd1cc72 205 SUPERFAMILY SSF102198 1 200 4.45E-58 T 06-07-2017 GTHT12_RS12310 81367c5c555b77fdeefc44233dd1cc72 205 Gene3D G3DSA:3.50.30.50 1 201 2.8E-60 T 06-07-2017 GTHT12_RS08370 7c766ce00b21188ae9387841f05181ef 144 SUPERFAMILY SSF55874 27 133 2.49E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS08370 7c766ce00b21188ae9387841f05181ef 144 Gene3D G3DSA:3.30.565.10 31 133 1.9E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS08370 7c766ce00b21188ae9387841f05181ef 144 Pfam PF13581 Histidine kinase-like ATPase domain 22 135 2.6E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain GTHT12_RS05135 483dded70ec4af83586719c98992a6c3 247 Gene3D G3DSA:2.60.40.920 155 238 3.9E-6 T 06-07-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain GTHT12_RS05135 483dded70ec4af83586719c98992a6c3 247 Pfam PF13115 YtkA-like 32 111 3.0E-15 T 06-07-2017 IPR032693 YtkA-like domain GTHT12_RS05135 483dded70ec4af83586719c98992a6c3 247 Pfam PF13115 YtkA-like 152 230 3.1E-11 T 06-07-2017 IPR032693 YtkA-like domain GTHT12_RS08750 88f75c4b31b09bbd10142725ce543a9e 449 Pfam PF02040 Arsenical pump membrane protein 4 440 9.2E-64 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 GTHT12_RS08750 88f75c4b31b09bbd10142725ce543a9e 449 PRINTS PR00758 Arsenical pump membrane protein signature 338 360 1.1E-37 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 GTHT12_RS08750 88f75c4b31b09bbd10142725ce543a9e 449 PRINTS PR00758 Arsenical pump membrane protein signature 102 126 1.1E-37 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 GTHT12_RS08750 88f75c4b31b09bbd10142725ce543a9e 449 PRINTS PR00758 Arsenical pump membrane protein signature 294 318 1.1E-37 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 GTHT12_RS08750 88f75c4b31b09bbd10142725ce543a9e 449 PRINTS PR00758 Arsenical pump membrane protein signature 412 436 1.1E-37 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 GTHT12_RS08750 88f75c4b31b09bbd10142725ce543a9e 449 PRINTS PR00758 Arsenical pump membrane protein signature 379 404 1.1E-37 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 GTHT12_RS10055 05abc2a2a48a641c8f4ee604f263c8a7 298 Gene3D G3DSA:3.20.20.150 3 295 1.5E-92 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain GTHT12_RS10055 05abc2a2a48a641c8f4ee604f263c8a7 298 TIGRFAM TIGR04379 myo_inos_iolE: myo-inosose-2 dehydratase 6 295 7.1E-134 T 06-07-2017 IPR030823 IolE/MocC family KEGG: 00562+4.2.1.44 GTHT12_RS10055 05abc2a2a48a641c8f4ee604f263c8a7 298 SUPERFAMILY SSF51658 8 295 7.73E-66 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain GTHT12_RS10055 05abc2a2a48a641c8f4ee604f263c8a7 298 Pfam PF01261 Xylose isomerase-like TIM barrel 37 250 5.4E-30 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain GTHT12_RS10055 05abc2a2a48a641c8f4ee604f263c8a7 298 Hamap MF_01672 Inosose dehydratase [iolE]. 2 298 58.079 T 06-07-2017 IPR023952 Inosose dehydratase GO:0019310|GO:0030145|GO:0050114 KEGG: 00562+4.2.1.44 GTHT12_RS17725 3ef9628a5db01ec5068bea28e6cfc161 62 Pfam PF01361 Tautomerase enzyme 2 60 2.6E-24 T 06-07-2017 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 GTHT12_RS17725 3ef9628a5db01ec5068bea28e6cfc161 62 SUPERFAMILY SSF55331 2 61 2.36E-20 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily GTHT12_RS17725 3ef9628a5db01ec5068bea28e6cfc161 62 Gene3D G3DSA:3.30.429.20 1 60 6.2E-28 T 06-07-2017 GTHT12_RS17725 3ef9628a5db01ec5068bea28e6cfc161 62 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 61 2.8E-28 T 06-07-2017 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 GTHT12_RS18685 613ea2a79fb3ec141e4727fba52a66f3 355 SUPERFAMILY SSF50199 127 266 4.05E-29 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold GTHT12_RS18685 613ea2a79fb3ec141e4727fba52a66f3 355 Pfam PF00565 Staphylococcal nuclease homologue 149 263 1.0E-20 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold GTHT12_RS18685 613ea2a79fb3ec141e4727fba52a66f3 355 SMART SM00894 318 354 8.0E-16 T 06-07-2017 IPR008613 Excalibur calcium-binding domain GTHT12_RS18685 613ea2a79fb3ec141e4727fba52a66f3 355 Gene3D G3DSA:2.40.50.90 130 266 4.5E-26 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold GTHT12_RS18685 613ea2a79fb3ec141e4727fba52a66f3 355 Pfam PF05901 Excalibur calcium-binding domain 319 354 6.7E-13 T 06-07-2017 IPR008613 Excalibur calcium-binding domain GTHT12_RS18685 613ea2a79fb3ec141e4727fba52a66f3 355 SMART SM00318 127 264 1.8E-19 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold GTHT12_RS09860 c2aa7b07fea65bde82581286a7cd86f8 317 Gene3D G3DSA:3.40.1190.20 1 314 2.1E-105 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS09860 c2aa7b07fea65bde82581286a7cd86f8 317 PRINTS PR00990 Ribokinase signature 183 198 4.1E-6 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 GTHT12_RS09860 c2aa7b07fea65bde82581286a7cd86f8 317 PRINTS PR00990 Ribokinase signature 27 46 4.1E-6 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 GTHT12_RS09860 c2aa7b07fea65bde82581286a7cd86f8 317 PRINTS PR00990 Ribokinase signature 222 233 4.1E-6 T 06-07-2017 IPR002139 Ribokinase/fructokinase GO:0004747|GO:0006014 GTHT12_RS09860 c2aa7b07fea65bde82581286a7cd86f8 317 Pfam PF00294 pfkB family carbohydrate kinase 2 300 6.0E-69 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB GTHT12_RS09860 c2aa7b07fea65bde82581286a7cd86f8 317 SUPERFAMILY SSF53613 1 308 1.56E-94 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS09860 c2aa7b07fea65bde82581286a7cd86f8 317 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 252 265 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 GTHT12_RS11075 50a40af57ae08bde6bca36440c6aba1c 60 Gene3D G3DSA:3.90.110.10 5 47 1.4E-7 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 GTHT12_RS11075 50a40af57ae08bde6bca36440c6aba1c 60 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 6 47 1.1E-8 T 06-07-2017 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 GTHT12_RS11075 50a40af57ae08bde6bca36440c6aba1c 60 SUPERFAMILY SSF56327 5 47 2.07E-7 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 GTHT12_RS03620 611221432f680b325df4cfba645d3f63 61 Pfam PF14147 Sporulation protein YhaL 4 55 9.1E-29 T 06-07-2017 IPR025428 Sporulation protein YhaL GTHT12_RS17945 edfbb79c1838537026dffb0593bcc887 508 SUPERFAMILY SSF51905 30 234 1.36E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS17945 edfbb79c1838537026dffb0593bcc887 508 SUPERFAMILY SSF51905 335 387 1.36E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS17945 edfbb79c1838537026dffb0593bcc887 508 SUPERFAMILY SSF50022 416 505 9.17E-27 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 GTHT12_RS17945 edfbb79c1838537026dffb0593bcc887 508 Pfam PF01266 FAD dependent oxidoreductase 31 375 2.1E-47 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 GTHT12_RS17945 edfbb79c1838537026dffb0593bcc887 508 Pfam PF00355 Rieske [2Fe-2S] domain 421 500 1.8E-15 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 GTHT12_RS17945 edfbb79c1838537026dffb0593bcc887 508 PRINTS PR00162 Rieske 2Fe-2S subunit signature 475 487 5.8E-8 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 GTHT12_RS17945 edfbb79c1838537026dffb0593bcc887 508 PRINTS PR00162 Rieske 2Fe-2S subunit signature 487 499 5.8E-8 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 GTHT12_RS17945 edfbb79c1838537026dffb0593bcc887 508 PRINTS PR00162 Rieske 2Fe-2S subunit signature 454 465 5.8E-8 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 GTHT12_RS17945 edfbb79c1838537026dffb0593bcc887 508 Gene3D G3DSA:3.50.50.60 22 120 3.3E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS17945 edfbb79c1838537026dffb0593bcc887 508 Gene3D G3DSA:3.50.50.60 168 248 3.3E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS17945 edfbb79c1838537026dffb0593bcc887 508 Gene3D G3DSA:3.50.50.60 335 392 3.3E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS17945 edfbb79c1838537026dffb0593bcc887 508 Gene3D G3DSA:2.102.10.10 407 505 3.8E-34 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 GTHT12_RS01240 7e93b5130b60fbe77aa1b24bc7fa835d 211 Pfam PF02659 Putative manganese efflux pump 69 206 8.6E-13 T 06-07-2017 IPR003810 Putative manganese efflux pump GTHT12_RS01240 7e93b5130b60fbe77aa1b24bc7fa835d 211 Pfam PF02659 Putative manganese efflux pump 4 58 4.1E-8 T 06-07-2017 IPR003810 Putative manganese efflux pump GTHT12_RS01240 7e93b5130b60fbe77aa1b24bc7fa835d 211 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 5 209 7.4E-64 T 06-07-2017 IPR014205 Sporulation protein YtaF GTHT12_RS12760 2d45c3ac2c067e2e9f9aea5dcbda91d9 147 Pfam PF15980 Putative Competence protein ComGF 53 139 4.8E-14 T 06-07-2017 IPR016977 Competence operon G, ComGF GTHT12_RS12760 2d45c3ac2c067e2e9f9aea5dcbda91d9 147 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 12 32 - T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site GTHT12_RS17410 e6cecaad475c88b4d015346e2af64d43 79 Pfam PF06612 Protein of unknown function (DUF1146) 17 64 2.2E-20 T 06-07-2017 IPR009526 Protein of unknown function DUF1146 GTHT12_RS17410 e6cecaad475c88b4d015346e2af64d43 79 TIGRFAM TIGR02327 int_mem_ywzB: conserved hypothetical integral membrane protein 10 77 1.5E-21 T 06-07-2017 IPR009526 Protein of unknown function DUF1146 GTHT12_RS00655 78f92333a00335f3ea636abddbda0ab8 102 Gene3D G3DSA:3.30.70.600 4 102 3.8E-45 T 06-07-2017 IPR027486 Ribosomal protein S10 domain GTHT12_RS00655 78f92333a00335f3ea636abddbda0ab8 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 28.481 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00655 78f92333a00335f3ea636abddbda0ab8 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 5.6E-47 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00655 78f92333a00335f3ea636abddbda0ab8 102 SUPERFAMILY SSF54999 5 102 2.88E-39 T 06-07-2017 IPR027486 Ribosomal protein S10 domain GTHT12_RS00655 78f92333a00335f3ea636abddbda0ab8 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 2.4E-37 T 06-07-2017 IPR027486 Ribosomal protein S10 domain GTHT12_RS00655 78f92333a00335f3ea636abddbda0ab8 102 SMART SM01403 7 101 3.3E-61 T 06-07-2017 IPR027486 Ribosomal protein S10 domain GTHT12_RS00655 78f92333a00335f3ea636abddbda0ab8 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 5.6E-20 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00655 78f92333a00335f3ea636abddbda0ab8 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 5.6E-20 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00655 78f92333a00335f3ea636abddbda0ab8 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 5.6E-20 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00655 78f92333a00335f3ea636abddbda0ab8 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 06-07-2017 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS18145 a7318a218677af5519b7de2e50ceef3c 658 Pfam PF02272 DHHA1 domain 590 645 8.2E-7 T 06-07-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 GTHT12_RS18145 a7318a218677af5519b7de2e50ceef3c 658 PIRSF PIRSF026583 1 657 7.1E-266 T 06-07-2017 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA GTHT12_RS18145 a7318a218677af5519b7de2e50ceef3c 658 Pfam PF01368 DHH family 340 497 1.8E-20 T 06-07-2017 IPR001667 DDH domain GTHT12_RS18145 a7318a218677af5519b7de2e50ceef3c 658 SUPERFAMILY SSF64182 339 641 1.44E-63 T 06-07-2017 GTHT12_RS18145 a7318a218677af5519b7de2e50ceef3c 658 Gene3D G3DSA:3.30.70.270 157 299 2.2E-5 T 06-07-2017 GTHT12_RS18145 a7318a218677af5519b7de2e50ceef3c 658 SMART SM00267 138 300 1.5E-6 T 06-07-2017 IPR000160 GGDEF domain GTHT12_RS18145 a7318a218677af5519b7de2e50ceef3c 658 Gene3D G3DSA:3.90.1640.10 339 534 8.1E-40 T 06-07-2017 GTHT12_RS04985 6d92e9e9c6d9c9d8a1b445de8ded7ba8 275 SUPERFAMILY SSF161098 7 274 2.24E-77 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS04985 6d92e9e9c6d9c9d8a1b445de8ded7ba8 275 Gene3D G3DSA:1.10.3720.10 3 263 4.7E-70 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS04985 6d92e9e9c6d9c9d8a1b445de8ded7ba8 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 269 3.8E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS03055 0efc3d70ce496e64abd65fb93ea1923f 165 Pfam PF00872 Transposase, Mutator family 14 165 1.2E-41 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS10065 88608f9eeb0420edb34b6adaa8115933 340 SUPERFAMILY SSF51735 3 150 9.07E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS10065 88608f9eeb0420edb34b6adaa8115933 340 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 134 233 2.9E-9 T 06-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10065 88608f9eeb0420edb34b6adaa8115933 340 TIGRFAM TIGR04380 myo_inos_iolG: inositol 2-dehydrogenase 3 330 1.4E-144 T 06-07-2017 IPR030827 Inositol 2-dehydrogenase GTHT12_RS10065 88608f9eeb0420edb34b6adaa8115933 340 Gene3D G3DSA:3.40.50.720 3 134 1.7E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS10065 88608f9eeb0420edb34b6adaa8115933 340 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 122 1.1E-26 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 GTHT12_RS10065 88608f9eeb0420edb34b6adaa8115933 340 Gene3D G3DSA:3.30.360.10 135 332 3.2E-63 T 06-07-2017 GTHT12_RS10065 88608f9eeb0420edb34b6adaa8115933 340 SUPERFAMILY SSF55347 127 290 8.37E-39 T 06-07-2017 GTHT12_RS05950 e09fabeef59f2acc4d3d76eda872ca59 143 Pfam PF04472 Protein of unknown function (DUF552) 55 126 2.4E-31 T 06-07-2017 IPR007561 Cell division protein SepF/SepF-related GO:0090529 GTHT12_RS05950 e09fabeef59f2acc4d3d76eda872ca59 143 Hamap MF_01197 Cell division protein SepF [sepF]. 1 134 20.496 T 06-07-2017 IPR023052 Cell division protein SepF GO:0090529 GTHT12_RS03410 aa7f10d77f10e93132af0d772d665faf 473 Pfam PF04293 SpoVR like protein 5 412 4.1E-167 T 06-07-2017 IPR007390 Sporulation stage V, protein R GTHT12_RS07275 61ef5b0eb4ab7d971b9d548b12178fab 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 2.5E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS07275 61ef5b0eb4ab7d971b9d548b12178fab 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 2.5E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS07275 61ef5b0eb4ab7d971b9d548b12178fab 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 2.5E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS07275 61ef5b0eb4ab7d971b9d548b12178fab 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 2.5E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS07275 61ef5b0eb4ab7d971b9d548b12178fab 147 Pfam PF13463 Winged helix DNA-binding domain 34 99 3.1E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS07275 61ef5b0eb4ab7d971b9d548b12178fab 147 SMART SM00347 25 126 2.8E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS07275 61ef5b0eb4ab7d971b9d548b12178fab 147 Gene3D G3DSA:1.10.10.10 6 145 4.0E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS07275 61ef5b0eb4ab7d971b9d548b12178fab 147 SUPERFAMILY SSF46785 8 143 3.44E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS03405 7f601c907c2eb51b7b670161e22fb637 201 Pfam PF09335 SNARE associated Golgi protein 30 156 4.4E-13 T 06-07-2017 IPR032816 SNARE associated Golgi protein GTHT12_RS04570 bb1c42b5883c614307c0332c2e506e57 242 SUPERFAMILY SSF53474 4 236 1.04E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS04570 bb1c42b5883c614307c0332c2e506e57 242 Gene3D G3DSA:3.40.50.1820 3 240 2.3E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS04570 bb1c42b5883c614307c0332c2e506e57 242 Pfam PF00756 Putative esterase 15 237 2.6E-48 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 GTHT12_RS02460 acc5fea3dcb6278d7d0af806458f76aa 386 Pfam PF14306 PUA-like domain 5 154 2.3E-49 T 06-07-2017 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 GTHT12_RS02460 acc5fea3dcb6278d7d0af806458f76aa 386 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 6 373 5.1E-135 T 06-07-2017 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 GTHT12_RS02460 acc5fea3dcb6278d7d0af806458f76aa 386 Gene3D G3DSA:3.10.400.10 6 174 4.6E-56 T 06-07-2017 GTHT12_RS02460 acc5fea3dcb6278d7d0af806458f76aa 386 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 21 377 49.775 T 06-07-2017 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 GTHT12_RS02460 acc5fea3dcb6278d7d0af806458f76aa 386 Gene3D G3DSA:3.40.50.620 175 379 3.5E-94 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS02460 acc5fea3dcb6278d7d0af806458f76aa 386 SUPERFAMILY SSF52374 164 377 8.76E-88 T 06-07-2017 GTHT12_RS02460 acc5fea3dcb6278d7d0af806458f76aa 386 Pfam PF01747 ATP-sulfurylase 164 373 2.3E-94 T 06-07-2017 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 GTHT12_RS02460 acc5fea3dcb6278d7d0af806458f76aa 386 SUPERFAMILY SSF88697 5 156 8.45E-47 T 06-07-2017 IPR015947 PUA-like domain GTHT12_RS01830 25085dfc88b08dae07851266ea405303 140 SUPERFAMILY SSF54637 5 137 6.23E-24 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS01830 25085dfc88b08dae07851266ea405303 140 Pfam PF13452 N-terminal half of MaoC dehydratase 17 127 2.4E-6 T 06-07-2017 GTHT12_RS01830 25085dfc88b08dae07851266ea405303 140 Gene3D G3DSA:3.10.129.10 6 133 6.1E-28 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS04775 a7e640d3037d6f8294d44334e7cdcf34 171 Pfam PF07681 DoxX 16 115 7.7E-12 T 06-07-2017 IPR032808 DoxX family GTHT12_RS08310 40fd465967f0c98b3e74db7f27c6d099 382 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 215 371 1.4E-18 T 06-07-2017 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 GTHT12_RS08310 40fd465967f0c98b3e74db7f27c6d099 382 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 5 372 5.2E-81 T 06-07-2017 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 GTHT12_RS17050 50ee06dfda496e139255f836b1d0f79b 85 Pfam PF10049 Protein of unknown function (DUF2283) 11 58 1.7E-9 T 06-07-2017 IPR019270 Protein of unknown function DUF2283 GTHT12_RS09960 d7e6a3c4e1fad98adfec2b0750bd9e48 502 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 293 493 2.4E-43 T 06-07-2017 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 GTHT12_RS09960 d7e6a3c4e1fad98adfec2b0750bd9e48 502 Gene3D G3DSA:3.20.20.80 42 356 4.0E-34 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS09960 d7e6a3c4e1fad98adfec2b0750bd9e48 502 SUPERFAMILY SSF51445 19 383 1.85E-118 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS09960 d7e6a3c4e1fad98adfec2b0750bd9e48 502 SMART SM00813 293 493 2.0E-98 T 06-07-2017 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 GTHT12_RS09960 d7e6a3c4e1fad98adfec2b0750bd9e48 502 SUPERFAMILY SSF51011 371 500 9.35E-48 T 06-07-2017 GTHT12_RS06395 6ae325970ab7d920b2a5f052094c83a9 119 SMART SM00448 2 114 7.3E-40 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS06395 6ae325970ab7d920b2a5f052094c83a9 119 SUPERFAMILY SSF52172 1 118 2.85E-40 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS06395 6ae325970ab7d920b2a5f052094c83a9 119 Pfam PF00072 Response regulator receiver domain 4 115 1.3E-33 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS06395 6ae325970ab7d920b2a5f052094c83a9 119 Gene3D G3DSA:3.40.50.2300 1 118 8.1E-41 T 06-07-2017 GTHT12_RS05500 67b16478d5f78ffc0818a07e619d379c 65 Pfam PF14156 Antirepressor AbbA 1 63 2.7E-30 T 06-07-2017 IPR025446 Antirepressor AbbA GTHT12_RS05500 67b16478d5f78ffc0818a07e619d379c 65 ProDom PD054279 YKZF 8 45 3.0E-12 T 06-07-2017 GTHT12_RS01080 5a5793cb276f85c74012391cc1aaf269 253 Gene3D G3DSA:3.40.50.1820 12 247 2.8E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS01080 5a5793cb276f85c74012391cc1aaf269 253 SUPERFAMILY SSF53474 11 246 3.69E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS01080 5a5793cb276f85c74012391cc1aaf269 253 Pfam PF00756 Putative esterase 13 196 3.8E-26 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 GTHT12_RS17715 db4ba24cde8e950ecfc85b88b8eede85 171 Pfam PF08741 YwhD family 6 166 2.1E-85 T 06-07-2017 IPR014852 Uncharacterised protein YwhD GTHT12_RS12270 b0adbefdd7fba558c369a76c0870921e 72 SMART SM00704 15 60 7.1E-6 T 06-07-2017 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 GTHT12_RS12270 b0adbefdd7fba558c369a76c0870921e 72 Pfam PF09360 Iron-binding zinc finger CDGSH type 11 55 1.4E-18 T 06-07-2017 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 GTHT12_RS02285 46132abb9bdb46adc6e9ac1be5d15009 386 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 4 126 2.6E-26 T 06-07-2017 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 GTHT12_RS02285 46132abb9bdb46adc6e9ac1be5d15009 386 SUPERFAMILY SSF55347 131 325 1.96E-40 T 06-07-2017 GTHT12_RS02285 46132abb9bdb46adc6e9ac1be5d15009 386 Gene3D G3DSA:3.40.50.720 3 172 3.4E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS02285 46132abb9bdb46adc6e9ac1be5d15009 386 SUPERFAMILY SSF51735 1 181 3.09E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS02285 46132abb9bdb46adc6e9ac1be5d15009 386 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 130 376 1.7E-39 T 06-07-2017 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 GTHT12_RS15335 4c635b122201c0bb7305c7ddf1a323ac 120 Pfam PF03334 Na+/H+ antiporter subunit 12 93 3.4E-26 T 06-07-2017 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 GTHT12_RS15335 4c635b122201c0bb7305c7ddf1a323ac 120 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 12 107 8.4E-30 T 06-07-2017 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 GTHT12_RS08915 e869c4ed48f9f5a9268a52b24f0b3904 212 Gene3D G3DSA:3.40.50.150 5 73 7.9E-4 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS08915 e869c4ed48f9f5a9268a52b24f0b3904 212 Pfam PF01610 Transposase 2 204 3.2E-49 T 06-07-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain GTHT12_RS02825 e0c936d0e71d45a9a61b803a1581e2c0 84 Pfam PF00563 EAL domain 8 55 6.7E-11 T 06-07-2017 IPR001633 EAL domain GTHT12_RS02825 e0c936d0e71d45a9a61b803a1581e2c0 84 SUPERFAMILY SSF141868 6 55 9.68E-12 T 06-07-2017 IPR001633 EAL domain GTHT12_RS02825 e0c936d0e71d45a9a61b803a1581e2c0 84 Gene3D G3DSA:3.20.20.450 7 56 9.7E-12 T 06-07-2017 IPR001633 EAL domain GTHT12_RS00015 0c19ca00ef6554b09ef9d89998a4ed1a 73 Pfam PF13275 S4 domain 5 67 9.6E-28 T 06-07-2017 GTHT12_RS00015 0c19ca00ef6554b09ef9d89998a4ed1a 73 Gene3D G3DSA:3.10.290.10 1 69 4.2E-27 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS00015 0c19ca00ef6554b09ef9d89998a4ed1a 73 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 4 62 1.8E-29 T 06-07-2017 IPR014330 RNA-binding S4-related,YaaA GTHT12_RS00015 0c19ca00ef6554b09ef9d89998a4ed1a 73 SUPERFAMILY SSF55174 3 68 2.16E-19 T 06-07-2017 GTHT12_RS06075 f5f8b91d0c0e1380b45cf0ad679f11d2 66 Gene3D G3DSA:3.90.940.10 1 64 2.8E-22 T 06-07-2017 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 GTHT12_RS06075 f5f8b91d0c0e1380b45cf0ad679f11d2 66 Pfam PF01192 RNA polymerase Rpb6 9 60 8.1E-16 T 06-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 GTHT12_RS06075 f5f8b91d0c0e1380b45cf0ad679f11d2 66 SUPERFAMILY SSF63562 1 63 5.49E-22 T 06-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 GTHT12_RS06075 f5f8b91d0c0e1380b45cf0ad679f11d2 66 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 16.009 T 06-07-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS06075 f5f8b91d0c0e1380b45cf0ad679f11d2 66 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 60 5.6E-18 T 06-07-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 GTHT12_RS06075 f5f8b91d0c0e1380b45cf0ad679f11d2 66 SMART SM01409 8 61 2.7E-15 T 06-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 GTHT12_RS16425 905d12bca493b9714e4d7d48255880ac 115 Pfam PF00436 Single-strand binding protein family 2 103 9.8E-34 T 06-07-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 GTHT12_RS16425 905d12bca493b9714e4d7d48255880ac 115 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 32.968 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 GTHT12_RS16425 905d12bca493b9714e4d7d48255880ac 115 Gene3D G3DSA:2.40.50.140 1 107 5.0E-41 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS16425 905d12bca493b9714e4d7d48255880ac 115 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 105 3.9E-35 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 GTHT12_RS16425 905d12bca493b9714e4d7d48255880ac 115 PIRSF PIRSF002070 1 112 1.3E-33 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 GTHT12_RS16425 905d12bca493b9714e4d7d48255880ac 115 SUPERFAMILY SSF50249 1 108 7.35E-43 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS09740 a330a26784a3b894adf5fc0e4edfca8f 376 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 16 182 1.4E-28 T 06-07-2017 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 GTHT12_RS09740 a330a26784a3b894adf5fc0e4edfca8f 376 SUPERFAMILY SSF53756 88 344 3.85E-22 T 06-07-2017 GTHT12_RS09740 a330a26784a3b894adf5fc0e4edfca8f 376 Gene3D G3DSA:3.40.50.2000 173 337 7.5E-16 T 06-07-2017 GTHT12_RS11140 b535d95a792f6644c8e55ceb2483620e 334 Gene3D G3DSA:3.40.50.2300 167 329 1.1E-69 T 06-07-2017 GTHT12_RS11140 b535d95a792f6644c8e55ceb2483620e 334 SUPERFAMILY SSF47413 1 59 1.29E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS11140 b535d95a792f6644c8e55ceb2483620e 334 Pfam PF13377 Periplasmic binding protein-like domain 167 328 1.8E-43 T 06-07-2017 GTHT12_RS11140 b535d95a792f6644c8e55ceb2483620e 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.8E-20 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS11140 b535d95a792f6644c8e55ceb2483620e 334 Gene3D G3DSA:3.40.50.2300 58 166 1.3E-40 T 06-07-2017 GTHT12_RS11140 b535d95a792f6644c8e55ceb2483620e 334 SUPERFAMILY SSF53822 61 329 1.58E-96 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS11140 b535d95a792f6644c8e55ceb2483620e 334 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 06-07-2017 GTHT12_RS11140 b535d95a792f6644c8e55ceb2483620e 334 Gene3D G3DSA:1.10.260.40 1 56 1.7E-23 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS11140 b535d95a792f6644c8e55ceb2483620e 334 SMART SM00354 1 71 4.2E-33 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS12620 f885fe4de2c70154ca5498a18efa6629 311 Pfam PF07136 Protein of unknown function (DUF1385) 56 298 1.5E-78 T 06-07-2017 IPR010787 Protein of unknown function DUF1385 GTHT12_RS12620 f885fe4de2c70154ca5498a18efa6629 311 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 56 294 3.0E-120 T 06-07-2017 IPR010787 Protein of unknown function DUF1385 GTHT12_RS02845 fce9e02ba7980929303f3840db999b7a 875 Pfam PF10070 Uncharacterized protein conserved in bacteria (DUF2309) 24 843 3.5E-262 T 06-07-2017 IPR018752 Uncharacterised protein family UPF0753 GTHT12_RS02845 fce9e02ba7980929303f3840db999b7a 875 Hamap MF_01871 UPF0753 protein . 19 858 24.19 T 06-07-2017 IPR018752 Uncharacterised protein family UPF0753 GTHT12_RS17350 9ddd0aed941d3821ed5168636797dedb 87 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 41 - T 06-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 GTHT12_RS17350 9ddd0aed941d3821ed5168636797dedb 87 Gene3D G3DSA:1.10.260.40 20 61 1.1E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS17350 9ddd0aed941d3821ed5168636797dedb 87 Pfam PF12116 Stage III sporulation protein D 2 82 1.8E-41 T 06-07-2017 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID GTHT12_RS17350 9ddd0aed941d3821ed5168636797dedb 87 TIGRFAM TIGR02844 spore_III_D: sporulation transcriptional regulator SpoIIID 2 81 4.0E-45 T 06-07-2017 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID GTHT12_RS08625 90e9b188702d486062c00f8e9793c708 707 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 11 169 2.1E-40 T 06-07-2017 IPR017500 Phage infection protein, YhgE, N-terminal GTHT12_RS08625 90e9b188702d486062c00f8e9793c708 707 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 487 683 8.8E-44 T 06-07-2017 IPR017501 Phage infection protein, YhgE, C-terminal GTHT12_RS08625 90e9b188702d486062c00f8e9793c708 707 Pfam PF12698 ABC-2 family transporter protein 502 682 4.2E-12 T 06-07-2017 GTHT12_RS07290 d22f257af22fe7e41942d2fe36754ea0 173 Pfam PF08281 Sigma-70, region 4 112 164 8.0E-14 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS07290 d22f257af22fe7e41942d2fe36754ea0 173 SUPERFAMILY SSF88946 13 101 6.28E-15 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS07290 d22f257af22fe7e41942d2fe36754ea0 173 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 38 70 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS07290 d22f257af22fe7e41942d2fe36754ea0 173 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 166 2.7E-22 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS07290 d22f257af22fe7e41942d2fe36754ea0 173 SUPERFAMILY SSF88659 93 170 3.74E-15 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS07290 d22f257af22fe7e41942d2fe36754ea0 173 Gene3D G3DSA:1.10.1740.10 13 85 1.2E-14 T 06-07-2017 GTHT12_RS07290 d22f257af22fe7e41942d2fe36754ea0 173 Pfam PF04542 Sigma-70 region 2 24 85 2.7E-8 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS07290 d22f257af22fe7e41942d2fe36754ea0 173 Gene3D G3DSA:1.10.10.10 108 171 2.2E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS09030 db2a63d527daabce6242343c1e1c22e8 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 2.0E-21 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS09030 db2a63d527daabce6242343c1e1c22e8 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 2.0E-21 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS09030 db2a63d527daabce6242343c1e1c22e8 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 2.0E-21 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS09030 db2a63d527daabce6242343c1e1c22e8 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 34 45 2.0E-21 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS09030 db2a63d527daabce6242343c1e1c22e8 115 SUPERFAMILY SSF46785 8 96 7.56E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS09030 db2a63d527daabce6242343c1e1c22e8 115 SMART SM00418 13 92 4.8E-28 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS09030 db2a63d527daabce6242343c1e1c22e8 115 Gene3D G3DSA:1.10.10.10 7 97 2.1E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS09030 db2a63d527daabce6242343c1e1c22e8 115 Pfam PF01022 Bacterial regulatory protein, arsR family 20 65 1.2E-18 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 GTHT12_RS16400 5e175df0833c482c26bdd0d672f37375 508 Pfam PF03023 MviN-like protein 29 461 4.6E-61 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ GTHT12_RS16400 5e175df0833c482c26bdd0d672f37375 508 PRINTS PR01806 Virulence factor MviN signature 436 453 5.6E-9 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ GTHT12_RS16400 5e175df0833c482c26bdd0d672f37375 508 PRINTS PR01806 Virulence factor MviN signature 254 280 5.6E-9 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ GTHT12_RS16400 5e175df0833c482c26bdd0d672f37375 508 PRINTS PR01806 Virulence factor MviN signature 130 154 5.6E-9 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ GTHT12_RS16400 5e175df0833c482c26bdd0d672f37375 508 PRINTS PR01806 Virulence factor MviN signature 34 53 5.6E-9 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ GTHT12_RS07900 1c09c19608f6ca89cb2a0d72119923d3 261 Gene3D G3DSA:3.30.450.40 79 256 3.4E-68 T 06-07-2017 IPR029016 GAF domain-like GTHT12_RS07900 1c09c19608f6ca89cb2a0d72119923d3 261 Gene3D G3DSA:1.10.10.10 6 78 1.9E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS07900 1c09c19608f6ca89cb2a0d72119923d3 261 Pfam PF09339 IclR helix-turn-helix domain 9 60 2.1E-16 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 GTHT12_RS07900 1c09c19608f6ca89cb2a0d72119923d3 261 SMART SM00346 7 97 1.6E-30 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 GTHT12_RS07900 1c09c19608f6ca89cb2a0d72119923d3 261 SUPERFAMILY SSF55781 65 254 6.15E-59 T 06-07-2017 IPR029016 GAF domain-like GTHT12_RS07900 1c09c19608f6ca89cb2a0d72119923d3 261 SUPERFAMILY SSF46785 7 80 2.73E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS07900 1c09c19608f6ca89cb2a0d72119923d3 261 Pfam PF01614 Bacterial transcriptional regulator 124 248 3.8E-41 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal GTHT12_RS06955 d240dd427fcf1a855e5eb6834dcb1f77 100 TIGRFAM TIGR00853 pts-lac: PTS system, lactose/cellobiose family IIB component 2 94 1.9E-38 T 06-07-2017 IPR013012 Phosphotransferase system, EIIB component, type 3 GO:0008982|GO:0009401 GTHT12_RS06955 d240dd427fcf1a855e5eb6834dcb1f77 100 SUPERFAMILY SSF52794 1 99 1.26E-35 T 06-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 GTHT12_RS06955 d240dd427fcf1a855e5eb6834dcb1f77 100 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 93 3.7E-25 T 06-07-2017 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 GTHT12_RS06955 d240dd427fcf1a855e5eb6834dcb1f77 100 Gene3D G3DSA:3.40.50.270 1 98 4.6E-37 T 06-07-2017 GTHT12_RS16275 b2b1dec79d6ccde147fbb44734b149cd 230 SUPERFAMILY SSF53271 84 229 2.36E-24 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS16275 b2b1dec79d6ccde147fbb44734b149cd 230 Pfam PF00156 Phosphoribosyl transferase domain 138 228 6.6E-10 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 GTHT12_RS16275 b2b1dec79d6ccde147fbb44734b149cd 230 Gene3D G3DSA:3.40.50.2020 58 229 6.7E-27 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like GTHT12_RS07855 0a4360d7e07e661fb9b5a74cf17ee074 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 60 4.4E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS07855 0a4360d7e07e661fb9b5a74cf17ee074 195 SUPERFAMILY SSF46689 4 78 1.5E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS07855 0a4360d7e07e661fb9b5a74cf17ee074 195 Gene3D G3DSA:1.10.357.10 6 192 3.5E-24 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 GTHT12_RS02870 2516af5d9bcc7ee95f3c13f0665bdf6e 393 Gene3D G3DSA:3.40.50.10540 2 216 3.6E-123 T 06-07-2017 IPR023606 CoA-transferase family III domain GTHT12_RS02870 2516af5d9bcc7ee95f3c13f0665bdf6e 393 Gene3D G3DSA:3.40.50.10540 305 376 3.6E-123 T 06-07-2017 IPR023606 CoA-transferase family III domain GTHT12_RS02870 2516af5d9bcc7ee95f3c13f0665bdf6e 393 Gene3D G3DSA:3.30.1540.10 222 304 2.9E-33 T 06-07-2017 GTHT12_RS02870 2516af5d9bcc7ee95f3c13f0665bdf6e 393 SUPERFAMILY SSF89796 3 382 2.35E-148 T 06-07-2017 IPR023606 CoA-transferase family III domain GTHT12_RS02870 2516af5d9bcc7ee95f3c13f0665bdf6e 393 Pfam PF02515 CoA-transferase family III 5 372 1.8E-144 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 GTHT12_RS15060 a9aab97a6feb7c726c39b1499a171d73 123 Gene3D G3DSA:3.40.630.30 9 123 1.7E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS15060 a9aab97a6feb7c726c39b1499a171d73 123 SUPERFAMILY SSF55729 6 123 1.05E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS15060 a9aab97a6feb7c726c39b1499a171d73 123 Pfam PF13673 Acetyltransferase (GNAT) domain 50 123 2.8E-11 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS03710 e3c4af070f2b2a418a000396bd13068c 45 Pfam PF14149 YhfH-like protein 4 38 8.1E-20 T 06-07-2017 IPR025432 YhfH-like protein GTHT12_RS04125 b94004a4b6df104892dbc1c83acf6279 510 Gene3D G3DSA:3.30.70.20 194 233 1.2E-23 T 06-07-2017 GTHT12_RS04125 b94004a4b6df104892dbc1c83acf6279 510 Gene3D G3DSA:3.30.70.20 10 26 5.2E-11 T 06-07-2017 GTHT12_RS04125 b94004a4b6df104892dbc1c83acf6279 510 Gene3D G3DSA:3.30.70.20 150 193 5.2E-11 T 06-07-2017 GTHT12_RS04125 b94004a4b6df104892dbc1c83acf6279 510 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 2 487 2.3E-249 T 06-07-2017 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 GTHT12_RS04125 b94004a4b6df104892dbc1c83acf6279 510 Pfam PF13247 4Fe-4S dicluster domain 173 268 4.1E-37 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain GTHT12_RS04125 b94004a4b6df104892dbc1c83acf6279 510 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 356 436 1.0E-29 T 06-07-2017 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 GTHT12_RS04125 b94004a4b6df104892dbc1c83acf6279 510 Gene3D G3DSA:1.10.3650.10 357 434 2.4E-30 T 06-07-2017 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 GTHT12_RS04125 b94004a4b6df104892dbc1c83acf6279 510 SUPERFAMILY SSF54862 2 487 7.12E-157 T 06-07-2017 GTHT12_RS04125 b94004a4b6df104892dbc1c83acf6279 510 Gene3D G3DSA:3.30.70.20 436 465 2.1E-68 T 06-07-2017 GTHT12_RS04125 b94004a4b6df104892dbc1c83acf6279 510 Gene3D G3DSA:3.30.70.20 234 356 2.1E-68 T 06-07-2017 GTHT12_RS00195 88ebe0f2ddca2b42a5e962e9186d9589 301 SUPERFAMILY SSF53790 14 232 2.88E-84 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS00195 88ebe0f2ddca2b42a5e962e9186d9589 301 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 94 105 - T 06-07-2017 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GTHT12_RS00195 88ebe0f2ddca2b42a5e962e9186d9589 301 PIRSF PIRSF005917 4 297 1.4E-105 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GTHT12_RS00195 88ebe0f2ddca2b42a5e962e9186d9589 301 Gene3D G3DSA:3.30.950.10 125 236 1.7E-43 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS00195 88ebe0f2ddca2b42a5e962e9186d9589 301 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 16 234 37.597 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GTHT12_RS00195 88ebe0f2ddca2b42a5e962e9186d9589 301 Gene3D G3DSA:3.40.1010.10 15 124 2.8E-14 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS00195 88ebe0f2ddca2b42a5e962e9186d9589 301 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 17 293 1.7E-84 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GTHT12_RS00195 88ebe0f2ddca2b42a5e962e9186d9589 301 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 16 215 4.1E-31 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 GTHT12_RS05565 fe5b55fc0bc9ac6233dde9b93c7bea6f 258 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 250 5.5E-60 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS05565 fe5b55fc0bc9ac6233dde9b93c7bea6f 258 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 224 1.9E-22 T 06-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 GTHT12_RS05565 fe5b55fc0bc9ac6233dde9b93c7bea6f 258 SUPERFAMILY SSF56784 4 255 4.45E-70 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS05565 fe5b55fc0bc9ac6233dde9b93c7bea6f 258 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 250 8.5E-66 T 06-07-2017 IPR000150 Cof protein GO:0016787 GTHT12_RS05565 fe5b55fc0bc9ac6233dde9b93c7bea6f 258 Gene3D G3DSA:3.40.50.1000 3 72 2.4E-58 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS05565 fe5b55fc0bc9ac6233dde9b93c7bea6f 258 Gene3D G3DSA:3.40.50.1000 160 255 2.4E-58 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS05565 fe5b55fc0bc9ac6233dde9b93c7bea6f 258 ProSitePatterns PS01229 Hypothetical cof family signature 2. 205 227 - T 06-07-2017 GTHT12_RS07660 d87c6ef379d97e08cfbf62e4512c65c4 311 Pfam PF12146 Serine aminopeptidase, S33 84 200 1.0E-13 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 GTHT12_RS07660 d87c6ef379d97e08cfbf62e4512c65c4 311 Gene3D G3DSA:3.40.50.1820 44 194 3.4E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS07660 d87c6ef379d97e08cfbf62e4512c65c4 311 Gene3D G3DSA:3.40.50.1820 235 304 3.4E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS07660 d87c6ef379d97e08cfbf62e4512c65c4 311 SUPERFAMILY SSF53474 34 304 4.3E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS10955 6640cdccf01ac5f077a343b623107d05 160 Gene3D G3DSA:3.40.1260.10 3 160 1.0E-56 T 06-07-2017 IPR027396 DsrEFH-like GTHT12_RS10955 6640cdccf01ac5f077a343b623107d05 160 Pfam PF13686 DsrE/DsrF/DrsH-like family 5 159 1.2E-66 T 06-07-2017 IPR032836 DsrE/DsrF/DrsH-like family GTHT12_RS10955 6640cdccf01ac5f077a343b623107d05 160 SUPERFAMILY SSF75169 6 52 3.24E-24 T 06-07-2017 IPR027396 DsrEFH-like GTHT12_RS10955 6640cdccf01ac5f077a343b623107d05 160 SUPERFAMILY SSF75169 102 158 3.24E-24 T 06-07-2017 IPR027396 DsrEFH-like GTHT12_RS18245 ebecaa8c625441be4f785a355c6cfd47 44 Pfam PF00468 Ribosomal protein L34 1 44 1.2E-24 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS18245 ebecaa8c625441be4f785a355c6cfd47 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 1.6E-22 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS18245 ebecaa8c625441be4f785a355c6cfd47 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 26 1.0E-7 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS18245 ebecaa8c625441be4f785a355c6cfd47 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 06-07-2017 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS18245 ebecaa8c625441be4f785a355c6cfd47 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.762 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS14050 dbf68fc5b6624ae3895185b7d096a68a 91 Hamap MF_02013 Cell division protein ZapA [zapA]. 1 85 26.535 T 06-07-2017 IPR023688 Cell division protein ZapA, firmicutes GO:0007049|GO:0051301 GTHT12_RS14050 dbf68fc5b6624ae3895185b7d096a68a 91 SUPERFAMILY SSF102829 8 83 7.19E-21 T 06-07-2017 IPR007838 Cell division protein ZapA-like GTHT12_RS14050 dbf68fc5b6624ae3895185b7d096a68a 91 Pfam PF05164 Cell division protein ZapA 9 81 1.9E-17 T 06-07-2017 IPR007838 Cell division protein ZapA-like GTHT12_RS11570 8c4e3f06e798cd984fac1466514381d1 289 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 11 215 8.5E-67 T 06-07-2017 IPR003740 Uncharacterised membrane protein YitT GTHT12_RS11570 8c4e3f06e798cd984fac1466514381d1 289 PIRSF PIRSF006483 4 283 3.5E-98 T 06-07-2017 IPR003740 Uncharacterised membrane protein YitT GTHT12_RS11570 8c4e3f06e798cd984fac1466514381d1 289 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 221 275 1.4E-23 T 06-07-2017 IPR019264 Domain of unknown function DUF2179 GTHT12_RS02035 24a838e64a63bb6b7e9c6ddfa89522d5 277 SUPERFAMILY SSF81301 4 150 1.64E-10 T 06-07-2017 GTHT12_RS02035 24a838e64a63bb6b7e9c6ddfa89522d5 277 Gene3D G3DSA:3.30.460.10 5 107 4.8E-12 T 06-07-2017 GTHT12_RS02035 24a838e64a63bb6b7e9c6ddfa89522d5 277 Pfam PF01909 Nucleotidyltransferase domain 8 109 3.5E-11 T 06-07-2017 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 GTHT12_RS13460 08c8dff5970c071eb98ff730846b24cb 426 Gene3D G3DSA:3.30.930.10 220 322 1.9E-97 T 06-07-2017 GTHT12_RS13460 08c8dff5970c071eb98ff730846b24cb 426 Gene3D G3DSA:3.30.930.10 1 184 1.9E-97 T 06-07-2017 GTHT12_RS13460 08c8dff5970c071eb98ff730846b24cb 426 SUPERFAMILY SSF55681 3 318 3.83E-100 T 06-07-2017 GTHT12_RS13460 08c8dff5970c071eb98ff730846b24cb 426 Gene3D G3DSA:3.40.50.800 328 419 1.7E-30 T 06-07-2017 IPR004154 Anticodon-binding GTHT12_RS13460 08c8dff5970c071eb98ff730846b24cb 426 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 424 34.858 T 06-07-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 GTHT12_RS13460 08c8dff5970c071eb98ff730846b24cb 426 Pfam PF13393 Histidyl-tRNA synthetase 8 313 4.4E-50 T 06-07-2017 GTHT12_RS13460 08c8dff5970c071eb98ff730846b24cb 426 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 410 6.0E-159 T 06-07-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 GTHT12_RS13460 08c8dff5970c071eb98ff730846b24cb 426 PIRSF PIRSF001549 1 422 5.9E-123 T 06-07-2017 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 GTHT12_RS13460 08c8dff5970c071eb98ff730846b24cb 426 SUPERFAMILY SSF52954 329 420 8.46E-26 T 06-07-2017 IPR004154 Anticodon-binding GTHT12_RS13460 08c8dff5970c071eb98ff730846b24cb 426 Pfam PF03129 Anticodon binding domain 331 420 5.9E-18 T 06-07-2017 IPR004154 Anticodon-binding GTHT12_RS11060 670d7a60ac87e431ec46e6cbe522f212 370 Pfam PF01168 Alanine racemase, N-terminal domain 10 227 1.4E-19 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 GTHT12_RS11060 670d7a60ac87e431ec46e6cbe522f212 370 Gene3D G3DSA:3.20.20.10 13 206 2.6E-16 T 06-07-2017 IPR029066 PLP-binding barrel GTHT12_RS11060 670d7a60ac87e431ec46e6cbe522f212 370 SUPERFAMILY SSF51419 10 225 9.81E-28 T 06-07-2017 IPR029066 PLP-binding barrel GTHT12_RS10550 b861118d4d3b347afdd8c4ae4ce7692f 285 Gene3D G3DSA:3.40.50.10490 110 268 4.1E-39 T 06-07-2017 GTHT12_RS10550 b861118d4d3b347afdd8c4ae4ce7692f 285 SUPERFAMILY SSF46689 4 77 2.87E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS10550 b861118d4d3b347afdd8c4ae4ce7692f 285 SUPERFAMILY SSF53697 98 278 4.84E-39 T 06-07-2017 GTHT12_RS10550 b861118d4d3b347afdd8c4ae4ce7692f 285 Pfam PF01380 SIS domain 131 259 2.1E-25 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 GTHT12_RS10550 b861118d4d3b347afdd8c4ae4ce7692f 285 Pfam PF01418 Helix-turn-helix domain, rpiR family 5 77 2.7E-16 T 06-07-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 GTHT12_RS10550 b861118d4d3b347afdd8c4ae4ce7692f 285 Gene3D G3DSA:1.10.10.10 4 78 9.9E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS13870 d768461916e88170b08107ae60aadc37 371 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 353 1.5E-145 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 GTHT12_RS13870 d768461916e88170b08107ae60aadc37 371 SMART SM01329 5 353 1.2E-208 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 GTHT12_RS13870 d768461916e88170b08107ae60aadc37 371 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 4 357 51.55 T 06-07-2017 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 GTHT12_RS13870 d768461916e88170b08107ae60aadc37 371 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 5 353 2.0E-165 T 06-07-2017 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 GTHT12_RS13870 d768461916e88170b08107ae60aadc37 371 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 06-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 GTHT12_RS13870 d768461916e88170b08107ae60aadc37 371 SUPERFAMILY SSF53659 2 354 2.11E-124 T 06-07-2017 GTHT12_RS13870 d768461916e88170b08107ae60aadc37 371 Gene3D G3DSA:3.40.718.10 2 355 3.3E-136 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 GTHT12_RS05360 720c4e0e395af680cd4a679678b5e7ad 87 Pfam PF00381 PTS HPr component phosphorylation site 2 81 1.8E-29 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like GTHT12_RS05360 720c4e0e395af680cd4a679678b5e7ad 87 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 2 80 7.2E-33 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like GTHT12_RS05360 720c4e0e395af680cd4a679678b5e7ad 87 PRINTS PR00107 Phosphocarrier protein signature 12 28 4.9E-26 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like GTHT12_RS05360 720c4e0e395af680cd4a679678b5e7ad 87 PRINTS PR00107 Phosphocarrier protein signature 52 69 4.9E-26 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like GTHT12_RS05360 720c4e0e395af680cd4a679678b5e7ad 87 PRINTS PR00107 Phosphocarrier protein signature 37 52 4.9E-26 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like GTHT12_RS05360 720c4e0e395af680cd4a679678b5e7ad 87 SUPERFAMILY SSF55594 2 82 1.3E-28 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like GTHT12_RS05360 720c4e0e395af680cd4a679678b5e7ad 87 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 38 53 - T 06-07-2017 IPR002114 Phosphotransferase system, HPr serine phosphorylation site GTHT12_RS05360 720c4e0e395af680cd4a679678b5e7ad 87 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 12 19 - T 06-07-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site GTHT12_RS05360 720c4e0e395af680cd4a679678b5e7ad 87 Gene3D G3DSA:3.30.1340.10 1 82 7.9E-34 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like GTHT12_RS07295 9966f92b647eb65ed64b7ae95424d3d4 160 Pfam PF11155 Domain of unknown function (DUF2935) 13 133 5.4E-18 T 06-07-2017 IPR021328 Protein of unknown function DUF2935 GTHT12_RS07295 9966f92b647eb65ed64b7ae95424d3d4 160 SUPERFAMILY SSF158430 1 137 1.57E-23 T 06-07-2017 GTHT12_RS07730 74e73b9cecca1262b28bc4fc65d7d236 397 Pfam PF01566 Natural resistance-associated macrophage protein 44 364 3.1E-19 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 GTHT12_RS14580 d240b21708fc2b007efbdc649a0467ff 210 Gene3D G3DSA:3.40.630.30 1 210 1.8E-89 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS14580 d240b21708fc2b007efbdc649a0467ff 210 Pfam PF00583 Acetyltransferase (GNAT) family 67 117 1.7E-4 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS14580 d240b21708fc2b007efbdc649a0467ff 210 PIRSF PIRSF021278 2 210 2.4E-87 T 06-07-2017 IPR024699 Acetoin utilization protein AcuA GO:0019152|GO:0045150 GTHT12_RS14580 d240b21708fc2b007efbdc649a0467ff 210 SUPERFAMILY SSF55729 47 117 3.49E-9 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS15835 d2109dad4d20cf7fd70ac4fbc04a22e5 87 ProDom PD058323 YUZF BH2251 6 70 8.0E-22 T 06-07-2017 IPR020139 Protein of unknown function DUF2642 GTHT12_RS15835 d2109dad4d20cf7fd70ac4fbc04a22e5 87 Pfam PF10842 Protein of unknown function (DUF2642) 9 71 6.5E-28 T 06-07-2017 IPR020139 Protein of unknown function DUF2642 GTHT12_RS15640 fffed5f28669502a876f0823b454b993 119 SMART SM00493 5 79 7.4E-8 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS15640 fffed5f28669502a876f0823b454b993 119 SUPERFAMILY SSF110455 2 109 1.14E-34 T 06-07-2017 GTHT12_RS15640 fffed5f28669502a876f0823b454b993 119 Pfam PF01751 Toprim domain 7 75 4.2E-6 T 06-07-2017 IPR006171 Toprim domain GTHT12_RS15640 fffed5f28669502a876f0823b454b993 119 Gene3D G3DSA:3.40.1360.20 3 111 1.4E-38 T 06-07-2017 GTHT12_RS10035 d028806c65fd8fb42cdb11cc8d530d48 295 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 134 145 - T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 GTHT12_RS10035 d028806c65fd8fb42cdb11cc8d530d48 295 SUPERFAMILY SSF51569 1 287 1.33E-104 T 06-07-2017 GTHT12_RS10035 d028806c65fd8fb42cdb11cc8d530d48 295 Gene3D G3DSA:3.20.20.70 1 288 3.4E-110 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS10035 d028806c65fd8fb42cdb11cc8d530d48 295 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 287 2.2E-109 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 GTHT12_RS10035 d028806c65fd8fb42cdb11cc8d530d48 295 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 286 1.4E-102 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 GTHT12_RS10035 d028806c65fd8fb42cdb11cc8d530d48 295 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 287 2.1E-121 T 06-07-2017 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 GTHT12_RS10035 d028806c65fd8fb42cdb11cc8d530d48 295 PIRSF PIRSF001359 1 287 4.1E-121 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 GTHT12_RS10035 d028806c65fd8fb42cdb11cc8d530d48 295 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 GTHT12_RS13830 1f6a4cc4a72268a397098331d3ef8365 195 Pfam PF01926 50S ribosome-binding GTPase 25 143 6.0E-22 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS13830 1f6a4cc4a72268a397098331d3ef8365 195 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 6 189 2.6E-71 T 06-07-2017 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 GTHT12_RS13830 1f6a4cc4a72268a397098331d3ef8365 195 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 193 28.505 T 06-07-2017 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 GTHT12_RS13830 1f6a4cc4a72268a397098331d3ef8365 195 SUPERFAMILY SSF52540 16 193 1.58E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13830 1f6a4cc4a72268a397098331d3ef8365 195 Gene3D G3DSA:3.40.50.300 3 192 2.2E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS09530 1b47c84793dccca949ec06be54084737 183 Pfam PF00857 Isochorismatase family 4 177 1.1E-36 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 GTHT12_RS09530 1b47c84793dccca949ec06be54084737 183 Gene3D G3DSA:3.40.50.850 3 182 3.4E-47 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 GTHT12_RS09530 1b47c84793dccca949ec06be54084737 183 SUPERFAMILY SSF52499 3 181 5.63E-50 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 GTHT12_RS02165 fe69aec93bbfd494afa7921bd6c6f12e 175 Pfam PF06414 Zeta toxin 56 172 1.3E-25 T 06-07-2017 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 GTHT12_RS02165 fe69aec93bbfd494afa7921bd6c6f12e 175 SUPERFAMILY SSF52540 67 172 1.86E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS02165 fe69aec93bbfd494afa7921bd6c6f12e 175 Gene3D G3DSA:3.40.50.300 63 169 4.7E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS05205 6a4238e24f0d7c9efd96ec6a46e7283d 123 Pfam PF13027 Protein of unknown function (DUF3888) 40 122 4.3E-15 T 06-07-2017 IPR024984 Protein of unknown function DUF3888 GTHT12_RS07860 2211b64bd5267b30cce4faafc3368cdb 264 PIRSF PIRSF006241 1 259 5.3E-99 T 06-07-2017 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 GTHT12_RS07860 2211b64bd5267b30cce4faafc3368cdb 264 Pfam PF01261 Xylose isomerase-like TIM barrel 20 217 4.9E-33 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain GTHT12_RS07860 2211b64bd5267b30cce4faafc3368cdb 264 TIGRFAM TIGR03234 OH-pyruv-isom: hydroxypyruvate isomerase 1 254 2.8E-107 T 06-07-2017 IPR017643 Hydroxypyruvate isomerase KEGG: 00630+5.3.1.22 GTHT12_RS07860 2211b64bd5267b30cce4faafc3368cdb 264 SUPERFAMILY SSF51658 1 256 1.05E-80 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain GTHT12_RS07860 2211b64bd5267b30cce4faafc3368cdb 264 Gene3D G3DSA:3.20.20.150 1 256 7.6E-86 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain GTHT12_RS09630 0436f71be2005e4c9711b501301306fe 325 PIRSF PIRSF038896 2 308 2.6E-93 T 06-07-2017 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 GTHT12_RS09630 0436f71be2005e4c9711b501301306fe 325 Pfam PF12706 Beta-lactamase superfamily domain 75 263 4.8E-40 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS09630 0436f71be2005e4c9711b501301306fe 325 SUPERFAMILY SSF56281 46 280 1.7E-35 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS09630 0436f71be2005e4c9711b501301306fe 325 Gene3D G3DSA:3.60.15.10 38 309 1.9E-76 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS13245 5069e8551e58d11c9483458b066da267 259 Pfam PF02666 Phosphatidylserine decarboxylase 59 257 7.2E-56 T 06-07-2017 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 GTHT12_RS13245 5069e8551e58d11c9483458b066da267 259 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 7 259 36.781 T 06-07-2017 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 GTHT12_RS13245 5069e8551e58d11c9483458b066da267 259 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 47 210 4.7E-46 T 06-07-2017 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 GTHT12_RS16975 33f5a54f9b1a0fbf4c4e61320ee6345b 427 SUPERFAMILY SSF53756 138 426 3.05E-43 T 06-07-2017 GTHT12_RS16975 33f5a54f9b1a0fbf4c4e61320ee6345b 427 SUPERFAMILY SSF53756 17 62 3.05E-43 T 06-07-2017 GTHT12_RS16975 33f5a54f9b1a0fbf4c4e61320ee6345b 427 Pfam PF00534 Glycosyl transferases group 1 244 404 6.2E-19 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 GTHT12_RS16975 33f5a54f9b1a0fbf4c4e61320ee6345b 427 Gene3D G3DSA:3.40.50.2000 233 404 2.6E-12 T 06-07-2017 GTHT12_RS01145 349c76a6621352b0768c5b32e82b2bb1 405 Gene3D G3DSA:3.40.640.10 60 307 2.0E-89 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS01145 349c76a6621352b0768c5b32e82b2bb1 405 Pfam PF00202 Aminotransferase class-III 16 396 9.8E-133 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GTHT12_RS01145 349c76a6621352b0768c5b32e82b2bb1 405 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 224 261 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GTHT12_RS01145 349c76a6621352b0768c5b32e82b2bb1 405 Hamap MF_01689 Ornithine aminotransferase [rocD]. 5 397 67.49 T 06-07-2017 IPR010164 Ornithine aminotransferase GO:0008483|GO:0030170 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 GTHT12_RS01145 349c76a6621352b0768c5b32e82b2bb1 405 SUPERFAMILY SSF53383 3 397 2.78E-129 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS01145 349c76a6621352b0768c5b32e82b2bb1 405 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 5 396 9.2E-165 T 06-07-2017 IPR010164 Ornithine aminotransferase GO:0008483|GO:0030170 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 GTHT12_RS01145 349c76a6621352b0768c5b32e82b2bb1 405 Gene3D G3DSA:3.90.1150.10 309 397 1.2E-40 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS01145 349c76a6621352b0768c5b32e82b2bb1 405 Gene3D G3DSA:3.90.1150.10 3 59 1.2E-40 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS01145 349c76a6621352b0768c5b32e82b2bb1 405 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 13 397 37.146 T 06-07-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 GTHT12_RS18160 4f4161aac04d82fba0ef865813f93755 164 SUPERFAMILY SSF50249 1 164 2.77E-59 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS18160 4f4161aac04d82fba0ef865813f93755 164 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 37.44 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 GTHT12_RS18160 4f4161aac04d82fba0ef865813f93755 164 Pfam PF00436 Single-strand binding protein family 2 103 8.2E-39 T 06-07-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 GTHT12_RS18160 4f4161aac04d82fba0ef865813f93755 164 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 164 8.9E-50 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 GTHT12_RS18160 4f4161aac04d82fba0ef865813f93755 164 Gene3D G3DSA:2.40.50.140 1 164 4.9E-52 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS16555 71e3c49b8c300f0314c23d8a97d46b1e 325 Gene3D G3DSA:3.40.50.920 197 320 3.6E-44 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GTHT12_RS16555 71e3c49b8c300f0314c23d8a97d46b1e 325 SUPERFAMILY SSF52518 4 193 3.31E-72 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS16555 71e3c49b8c300f0314c23d8a97d46b1e 325 Pfam PF02780 Transketolase, C-terminal domain 194 315 4.2E-38 T 06-07-2017 IPR033248 Transketolase, C-terminal domain GTHT12_RS16555 71e3c49b8c300f0314c23d8a97d46b1e 325 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 5.1E-49 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain GTHT12_RS16555 71e3c49b8c300f0314c23d8a97d46b1e 325 SMART SM00861 4 179 4.4E-69 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain GTHT12_RS16555 71e3c49b8c300f0314c23d8a97d46b1e 325 SUPERFAMILY SSF52922 189 324 2.75E-40 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 GTHT12_RS16555 71e3c49b8c300f0314c23d8a97d46b1e 325 Gene3D G3DSA:3.40.50.970 2 196 7.0E-84 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS10740 81b340577b4461497c869e1f587c97fa 288 PIRSF PIRSF020623 1 286 5.2E-111 T 06-07-2017 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 GTHT12_RS10740 81b340577b4461497c869e1f587c97fa 288 TIGRFAM TIGR02277 PaaX_trns_reg: phenylacetic acid degradation operon negative regulatory protein PaaX 5 277 1.6E-109 T 06-07-2017 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 GTHT12_RS10740 81b340577b4461497c869e1f587c97fa 288 Gene3D G3DSA:1.10.10.10 30 81 2.7E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS10740 81b340577b4461497c869e1f587c97fa 288 Pfam PF08223 PaaX-like protein C-terminal domain 89 257 2.8E-63 T 06-07-2017 IPR013225 PaaX-like, C-terminal GTHT12_RS10740 81b340577b4461497c869e1f587c97fa 288 Pfam PF07848 PaaX-like protein 3 71 4.0E-32 T 06-07-2017 IPR012906 PaaX-like, N-terminal GTHT12_RS10740 81b340577b4461497c869e1f587c97fa 288 SUPERFAMILY SSF46785 14 85 3.9E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12235 920aec762bd8ea74c51cb699339f08c8 396 Pfam PF13263 PHP-associated 205 252 2.9E-7 T 06-07-2017 GTHT12_RS12235 920aec762bd8ea74c51cb699339f08c8 396 Gene3D G3DSA:1.10.150.20 327 373 3.3E-5 T 06-07-2017 GTHT12_RS12235 920aec762bd8ea74c51cb699339f08c8 396 SUPERFAMILY SSF47781 314 373 2.13E-6 T 06-07-2017 IPR010994 RuvA domain 2-like GTHT12_RS12235 920aec762bd8ea74c51cb699339f08c8 396 Gene3D G3DSA:3.20.20.140 13 243 2.4E-5 T 06-07-2017 GTHT12_RS12235 920aec762bd8ea74c51cb699339f08c8 396 SUPERFAMILY SSF89550 12 254 7.46E-15 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 GTHT12_RS00395 ce637f5279b5da382c0143c0cf81cdd9 308 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 304 1.2E-137 T 06-07-2017 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 GTHT12_RS00395 ce637f5279b5da382c0143c0cf81cdd9 308 SUPERFAMILY SSF53686 4 305 3.93E-108 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GTHT12_RS00395 ce637f5279b5da382c0143c0cf81cdd9 308 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 34 52 - T 06-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 GTHT12_RS00395 ce637f5279b5da382c0143c0cf81cdd9 308 Gene3D G3DSA:3.40.50.1100 136 304 1.6E-76 T 06-07-2017 GTHT12_RS00395 ce637f5279b5da382c0143c0cf81cdd9 308 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 292 3.1E-74 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GTHT12_RS00395 ce637f5279b5da382c0143c0cf81cdd9 308 Gene3D G3DSA:3.40.50.1100 39 135 1.1E-46 T 06-07-2017 GTHT12_RS00395 ce637f5279b5da382c0143c0cf81cdd9 308 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 304 1.1E-145 T 06-07-2017 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 GTHT12_RS17535 463838cde18d078ae6c91a980123dbff 148 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 142 1.1E-56 T 06-07-2017 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 GTHT12_RS17535 463838cde18d078ae6c91a980123dbff 148 PIRSF PIRSF005384 1 147 1.4E-59 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 GTHT12_RS17535 463838cde18d078ae6c91a980123dbff 148 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 146 3.2E-62 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 GTHT12_RS17535 463838cde18d078ae6c91a980123dbff 148 Pfam PF02502 Ribose/Galactose Isomerase 3 140 4.2E-59 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 GTHT12_RS17535 463838cde18d078ae6c91a980123dbff 148 SUPERFAMILY SSF89623 2 144 6.15E-61 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 GTHT12_RS17535 463838cde18d078ae6c91a980123dbff 148 Gene3D G3DSA:3.40.1400.10 2 147 9.2E-68 T 06-07-2017 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 GTHT12_RS04760 718561c223616eaed8427c1c50feaa39 396 Pfam PF01610 Transposase 155 382 5.4E-66 T 06-07-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain GTHT12_RS04760 718561c223616eaed8427c1c50feaa39 396 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 34 78 8.5E-14 T 06-07-2017 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger GTHT12_RS04760 718561c223616eaed8427c1c50feaa39 396 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 86 132 5.5E-10 T 06-07-2017 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain GTHT12_RS04210 28895e319a50f76526c0d5b1620767af 258 Hamap MF_00082_B Acetylglutamate kinase [argB]. 1 252 32.251 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 GTHT12_RS04210 28895e319a50f76526c0d5b1620767af 258 Gene3D G3DSA:3.40.1160.10 1 250 5.7E-86 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase GTHT12_RS04210 28895e319a50f76526c0d5b1620767af 258 PIRSF PIRSF000728 1 253 2.0E-93 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 GTHT12_RS04210 28895e319a50f76526c0d5b1620767af 258 Pfam PF00696 Amino acid kinase family 3 233 8.0E-43 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase GTHT12_RS04210 28895e319a50f76526c0d5b1620767af 258 SUPERFAMILY SSF53633 2 252 4.06E-71 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase GTHT12_RS04210 28895e319a50f76526c0d5b1620767af 258 TIGRFAM TIGR00761 argB: acetylglutamate kinase 4 232 6.4E-81 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 GTHT12_RS04210 28895e319a50f76526c0d5b1620767af 258 PRINTS PR00474 Glutamate 5-kinase family signature 126 147 5.6E-5 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 GTHT12_RS04210 28895e319a50f76526c0d5b1620767af 258 PRINTS PR00474 Glutamate 5-kinase family signature 158 185 5.6E-5 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 GTHT12_RS04210 28895e319a50f76526c0d5b1620767af 258 PRINTS PR00474 Glutamate 5-kinase family signature 32 46 5.6E-5 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 GTHT12_RS16845 faa2b5f34badc05f3f8915c61f5274e3 337 SUPERFAMILY SSF47413 3 50 2.98E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS16845 faa2b5f34badc05f3f8915c61f5274e3 337 SUPERFAMILY SSF53822 66 335 1.35E-59 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS16845 faa2b5f34badc05f3f8915c61f5274e3 337 Gene3D G3DSA:1.10.260.40 4 48 1.1E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS16845 faa2b5f34badc05f3f8915c61f5274e3 337 Gene3D G3DSA:3.40.50.2300 63 175 2.5E-26 T 06-07-2017 GTHT12_RS16845 faa2b5f34badc05f3f8915c61f5274e3 337 Pfam PF13377 Periplasmic binding protein-like domain 172 331 1.8E-37 T 06-07-2017 GTHT12_RS16845 faa2b5f34badc05f3f8915c61f5274e3 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 48 1.1E-10 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS16845 faa2b5f34badc05f3f8915c61f5274e3 337 Gene3D G3DSA:3.40.50.2300 176 312 2.8E-38 T 06-07-2017 GTHT12_RS16845 faa2b5f34badc05f3f8915c61f5274e3 337 SMART SM00354 4 74 7.3E-7 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 GTHT12_RS12315 ded548e5661bc5ee69d8df1242fa65cd 455 PRINTS PR00131 Glycosyl hydrolase family 1 signature 372 383 2.3E-16 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 GTHT12_RS12315 ded548e5661bc5ee69d8df1242fa65cd 455 PRINTS PR00131 Glycosyl hydrolase family 1 signature 417 429 2.3E-16 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 GTHT12_RS12315 ded548e5661bc5ee69d8df1242fa65cd 455 PRINTS PR00131 Glycosyl hydrolase family 1 signature 289 303 2.3E-16 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 GTHT12_RS12315 ded548e5661bc5ee69d8df1242fa65cd 455 PRINTS PR00131 Glycosyl hydrolase family 1 signature 351 359 2.3E-16 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 GTHT12_RS12315 ded548e5661bc5ee69d8df1242fa65cd 455 PRINTS PR00131 Glycosyl hydrolase family 1 signature 393 410 2.3E-16 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 GTHT12_RS12315 ded548e5661bc5ee69d8df1242fa65cd 455 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 351 359 - T 06-07-2017 IPR018120 Glycoside hydrolase family 1, active site GTHT12_RS12315 ded548e5661bc5ee69d8df1242fa65cd 455 Gene3D G3DSA:3.20.20.80 9 453 8.1E-148 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS12315 ded548e5661bc5ee69d8df1242fa65cd 455 Pfam PF00232 Glycosyl hydrolase family 1 8 452 1.2E-148 T 06-07-2017 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 GTHT12_RS12315 ded548e5661bc5ee69d8df1242fa65cd 455 SUPERFAMILY SSF51445 9 453 4.51E-162 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS12315 ded548e5661bc5ee69d8df1242fa65cd 455 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 13 27 - T 06-07-2017 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site GTHT12_RS00505 9a1822994b11b0195751c03c48be057d 153 PIRSF PIRSF010607 1 153 2.8E-68 T 06-07-2017 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 GTHT12_RS00505 9a1822994b11b0195751c03c48be057d 153 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 3 150 3.1E-60 T 06-07-2017 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 GTHT12_RS17900 685cc5411be342f956a60233bf0412de 99 TIGRFAM TIGR02901 QoxD: cytochrome aa3 quinol oxidase, subunit IV 6 98 1.9E-41 T 06-07-2017 IPR014250 Quinol oxidase subunit IV GO:0016021|GO:0016682|GO:0042773 GTHT12_RS17900 685cc5411be342f956a60233bf0412de 99 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 15 88 8.2E-12 T 06-07-2017 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 GTHT12_RS02080 fcf50f70fdb1b64837051951c1daa312 463 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 391 422 - T 06-07-2017 IPR030390 RNA methyltransferase TrmA, active site GTHT12_RS02080 fcf50f70fdb1b64837051951c1daa312 463 Gene3D G3DSA:3.40.50.150 259 460 2.3E-63 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS02080 fcf50f70fdb1b64837051951c1daa312 463 Gene3D G3DSA:2.40.50.140 7 87 7.4E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS02080 fcf50f70fdb1b64837051951c1daa312 463 SUPERFAMILY SSF53335 76 460 3.83E-79 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS02080 fcf50f70fdb1b64837051951c1daa312 463 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 96 460 3.1E-25 T 06-07-2017 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 GTHT12_RS02080 fcf50f70fdb1b64837051951c1daa312 463 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 443 453 - T 06-07-2017 IPR030391 RNA methyltransferase TrmA, conserved site GTHT12_RS02080 fcf50f70fdb1b64837051951c1daa312 463 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 32 453 2.3E-107 T 06-07-2017 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 GTHT12_RS14300 0f30dc77987c0f17a7ea546125e40fde 120 Gene3D G3DSA:3.10.450.50 7 117 1.9E-21 T 06-07-2017 IPR032710 NTF2-like domain GTHT12_RS14300 0f30dc77987c0f17a7ea546125e40fde 120 Pfam PF14534 Domain of unknown function (DUF4440) 11 109 6.0E-15 T 06-07-2017 IPR027843 Domain of unknown function DUF4440 GTHT12_RS14300 0f30dc77987c0f17a7ea546125e40fde 120 SUPERFAMILY SSF54427 7 116 1.58E-22 T 06-07-2017 IPR032710 NTF2-like domain GTHT12_RS02625 54c4e1a95d22b7b210cab15ce271a29f 97 SUPERFAMILY SSF140453 4 96 1.22E-22 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like GTHT12_RS02625 54c4e1a95d22b7b210cab15ce271a29f 97 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 1.2E-24 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like GTHT12_RS02625 54c4e1a95d22b7b210cab15ce271a29f 97 Gene3D G3DSA:1.10.287.1060 5 93 1.2E-13 T 06-07-2017 GTHT12_RS02625 54c4e1a95d22b7b210cab15ce271a29f 97 Pfam PF06013 Proteins of 100 residues with WXG 5 89 5.4E-21 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like GTHT12_RS18925 163e004effd47f35976cd702f7a68a57 330 Pfam PF08401 Domain of unknown function (DUF1738) 46 132 1.4E-5 T 06-07-2017 IPR013610 Domain of unknown function DUF1738 GTHT12_RS00170 41de6d567a4ffebc3a4b1b266ea779f8 225 Pfam PF02223 Thymidylate kinase 8 197 3.1E-53 T 06-07-2017 GTHT12_RS00170 41de6d567a4ffebc3a4b1b266ea779f8 225 ProSitePatterns PS01331 Thymidylate kinase signature. 93 105 - T 06-07-2017 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 GTHT12_RS00170 41de6d567a4ffebc3a4b1b266ea779f8 225 Gene3D G3DSA:3.40.50.300 3 208 2.9E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00170 41de6d567a4ffebc3a4b1b266ea779f8 225 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 195 2.1E-60 T 06-07-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 GTHT12_RS00170 41de6d567a4ffebc3a4b1b266ea779f8 225 Hamap MF_00165 Thymidylate kinase [tmk]. 4 207 31.687 T 06-07-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 GTHT12_RS00170 41de6d567a4ffebc3a4b1b266ea779f8 225 SUPERFAMILY SSF52540 1 208 9.07E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12335 2d9fd0dd0ba94820cde9e722fbea3880 292 Pfam PF13612 Transposase DDE domain 111 267 2.1E-28 T 06-07-2017 IPR025668 Transposase DDE domain GTHT12_RS08800 2d9fd0dd0ba94820cde9e722fbea3880 292 Pfam PF13612 Transposase DDE domain 111 267 2.1E-28 T 06-07-2017 IPR025668 Transposase DDE domain GTHT12_RS08105 2d9fd0dd0ba94820cde9e722fbea3880 292 Pfam PF13612 Transposase DDE domain 111 267 2.1E-28 T 06-07-2017 IPR025668 Transposase DDE domain GTHT12_RS05340 c5b85af38371279846260a8d80d028c3 212 SUPERFAMILY SSF55469 9 209 1.96E-53 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 GTHT12_RS05340 c5b85af38371279846260a8d80d028c3 212 Gene3D G3DSA:3.40.109.10 6 209 6.9E-61 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 GTHT12_RS05340 c5b85af38371279846260a8d80d028c3 212 Pfam PF00881 Nitroreductase family 16 190 3.6E-34 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 GTHT12_RS13150 9b741b381db73556eae80e0defb2a844 112 ProDom PD072942 YQXA ORF79 1 107 5.0E-34 T 06-07-2017 IPR020534 Uncharacterised protein family YqxA GTHT12_RS13150 9b741b381db73556eae80e0defb2a844 112 Pfam PF12438 Protein of unknown function (DUF3679) 8 62 3.2E-24 T 06-07-2017 IPR020534 Uncharacterised protein family YqxA GTHT12_RS16155 2dc4e18e81f667b048a217065b278077 128 Gene3D G3DSA:2.40.70.10 14 120 6.4E-4 T 06-07-2017 IPR021109 Aspartic peptidase domain GTHT12_RS16155 2dc4e18e81f667b048a217065b278077 128 SUPERFAMILY SSF50630 25 120 4.5E-9 T 06-07-2017 IPR021109 Aspartic peptidase domain GTHT12_RS12285 26fdf359d2625717218869c0001ce3be 323 Pfam PF00753 Metallo-beta-lactamase superfamily 18 231 4.2E-22 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS12285 26fdf359d2625717218869c0001ce3be 323 SMART SM00849 19 231 1.3E-23 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS12285 26fdf359d2625717218869c0001ce3be 323 Gene3D G3DSA:3.60.15.10 6 258 1.0E-41 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS12285 26fdf359d2625717218869c0001ce3be 323 SUPERFAMILY SSF56281 4 316 5.24E-53 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS14245 acca6e137d641efe4a2ada8ae21178d1 372 Pfam PF01594 Domain of unknown function DUF20 13 353 3.0E-69 T 06-07-2017 IPR002549 Transmembrane protein TqsA-like GTHT12_RS14245 acca6e137d641efe4a2ada8ae21178d1 372 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 11 359 7.2E-114 T 06-07-2017 IPR014227 Sporulation integral membrane protein YtvI GTHT12_RS18765 2fc35847e3c5f403ebf74c7b7219e2b6 54 Pfam PF12841 YvrJ protein family 12 46 1.7E-14 T 06-07-2017 IPR024419 Protein of unknown function YvrJ GTHT12_RS13985 df672e6e746fbf260826c9f7088913bb 260 Gene3D G3DSA:3.40.50.300 8 209 1.6E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13985 df672e6e746fbf260826c9f7088913bb 260 SMART SM00382 33 207 1.5E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS13985 df672e6e746fbf260826c9f7088913bb 260 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS13985 df672e6e746fbf260826c9f7088913bb 260 SUPERFAMILY SSF52540 11 231 8.21E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13985 df672e6e746fbf260826c9f7088913bb 260 Pfam PF00005 ABC transporter 24 157 1.5E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS06725 3d9820907a88c33ec0e78c18d5e261f1 264 Gene3D G3DSA:3.60.21.30 1 260 4.8E-120 T 06-07-2017 GTHT12_RS06725 3d9820907a88c33ec0e78c18d5e261f1 264 PIRSF PIRSF004789 1 263 3.4E-103 T 06-07-2017 IPR005235 Metallophosphoesterase, YmdB-like GTHT12_RS06725 3d9820907a88c33ec0e78c18d5e261f1 264 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 264 1.0E-110 T 06-07-2017 IPR005235 Metallophosphoesterase, YmdB-like GTHT12_RS06725 3d9820907a88c33ec0e78c18d5e261f1 264 SUPERFAMILY SSF56300 1 255 1.3E-88 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like GTHT12_RS06725 3d9820907a88c33ec0e78c18d5e261f1 264 Pfam PF13277 YmdB-like protein 4 253 1.1E-111 T 06-07-2017 IPR005235 Metallophosphoesterase, YmdB-like GTHT12_RS00285 5a62ee6e12d55c21327a74d3b90b11b0 76 Pfam PF10955 Protein of unknown function (DUF2757) 1 76 4.7E-37 T 06-07-2017 IPR020115 Anti-sigma-F factor Fin GO:0010468 GTHT12_RS00285 5a62ee6e12d55c21327a74d3b90b11b0 76 ProDom PD057826 YABK 4 75 1.0E-34 T 06-07-2017 IPR020115 Anti-sigma-F factor Fin GO:0010468 GTHT12_RS04065 0ed87d75e31ff62bb2119544f0c2a52c 787 SUPERFAMILY SSF81442 292 772 1.57E-87 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS04065 0ed87d75e31ff62bb2119544f0c2a52c 787 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 306 746 8.8E-68 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05860 6eec39687fa12857c23a68cd956253f8 489 Gene3D G3DSA:3.90.190.20 336 478 1.3E-58 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GTHT12_RS05860 6eec39687fa12857c23a68cd956253f8 489 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 22 485 6.5E-178 T 06-07-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 GTHT12_RS05860 6eec39687fa12857c23a68cd956253f8 489 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 485 37.716 T 06-07-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 GTHT12_RS05860 6eec39687fa12857c23a68cd956253f8 489 SUPERFAMILY SSF53623 97 330 4.45E-79 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GTHT12_RS05860 6eec39687fa12857c23a68cd956253f8 489 Pfam PF01225 Mur ligase family, catalytic domain 25 94 7.5E-15 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 GTHT12_RS05860 6eec39687fa12857c23a68cd956253f8 489 Pfam PF02875 Mur ligase family, glutamate ligase domain 332 417 1.9E-25 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GTHT12_RS05860 6eec39687fa12857c23a68cd956253f8 489 SUPERFAMILY SSF63418 1 97 2.75E-27 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 GTHT12_RS05860 6eec39687fa12857c23a68cd956253f8 489 Gene3D G3DSA:3.40.1190.10 98 335 1.2E-87 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GTHT12_RS05860 6eec39687fa12857c23a68cd956253f8 489 Pfam PF08245 Mur ligase middle domain 106 312 2.5E-59 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 GTHT12_RS05860 6eec39687fa12857c23a68cd956253f8 489 SUPERFAMILY SSF53244 332 487 2.49E-52 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 GTHT12_RS05860 6eec39687fa12857c23a68cd956253f8 489 Gene3D G3DSA:3.40.1390.10 5 96 2.8E-26 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 GTHT12_RS16335 cd67014c04d5e45243e2cd8b71ce1a5c 337 Gene3D G3DSA:3.90.25.10 179 231 4.1E-54 T 06-07-2017 GTHT12_RS16335 cd67014c04d5e45243e2cd8b71ce1a5c 337 Gene3D G3DSA:3.90.25.10 263 336 4.1E-54 T 06-07-2017 GTHT12_RS16335 cd67014c04d5e45243e2cd8b71ce1a5c 337 SUPERFAMILY SSF51735 1 336 1.26E-100 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS16335 cd67014c04d5e45243e2cd8b71ce1a5c 337 Gene3D G3DSA:3.40.50.720 1 178 5.4E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS16335 cd67014c04d5e45243e2cd8b71ce1a5c 337 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 323 2.3E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS16335 cd67014c04d5e45243e2cd8b71ce1a5c 337 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 334 4.4E-144 T 06-07-2017 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 GTHT12_RS07145 24100126b106d5566a53c2895b2dd078 253 Pfam PF14335 Domain of unknown function (DUF4391) 20 245 1.2E-55 T 06-07-2017 IPR025503 Protein of unknown function DUF4391 GTHT12_RS11815 e268631d4ceacd3ce0fe5a3320bdf7b1 263 Gene3D G3DSA:1.10.101.10 28 96 5.8E-23 T 06-07-2017 IPR002477 Peptidoglycan binding-like GTHT12_RS11815 e268631d4ceacd3ce0fe5a3320bdf7b1 263 TIGRFAM TIGR02869 spore_SleB: spore cortex-lytic enzyme 25 263 2.8E-102 T 06-07-2017 IPR014224 Spore cortex-lytic enzyme SleB GO:0003824|GO:0009847 GTHT12_RS11815 e268631d4ceacd3ce0fe5a3320bdf7b1 263 Pfam PF01471 Putative peptidoglycan binding domain 37 92 5.2E-18 T 06-07-2017 IPR002477 Peptidoglycan binding-like GTHT12_RS11815 e268631d4ceacd3ce0fe5a3320bdf7b1 263 SUPERFAMILY SSF47090 26 93 2.17E-21 T 06-07-2017 IPR002477 Peptidoglycan binding-like GTHT12_RS11815 e268631d4ceacd3ce0fe5a3320bdf7b1 263 Pfam PF07486 Cell Wall Hydrolase 164 262 7.8E-28 T 06-07-2017 IPR011105 Cell wall hydrolase, SleB GO:0016787 GTHT12_RS04440 a70fbd2ba6300d4423df04f8efbbd23c 339 SUPERFAMILY SSF56112 11 328 2.65E-31 T 06-07-2017 IPR011009 Protein kinase-like domain GTHT12_RS04440 a70fbd2ba6300d4423df04f8efbbd23c 339 Gene3D G3DSA:3.90.1200.10 98 327 1.1E-48 T 06-07-2017 GTHT12_RS04440 a70fbd2ba6300d4423df04f8efbbd23c 339 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 22 331 8.9E-77 T 06-07-2017 IPR014255 Spore coat protein CotS GTHT12_RS04440 a70fbd2ba6300d4423df04f8efbbd23c 339 Gene3D G3DSA:3.30.200.20 3 97 1.4E-22 T 06-07-2017 GTHT12_RS11155 c558598ee6a0924496823c2af125ef92 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 268 2.4E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS11155 c558598ee6a0924496823c2af125ef92 275 Gene3D G3DSA:1.10.3720.10 5 262 2.2E-67 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS11155 c558598ee6a0924496823c2af125ef92 275 SUPERFAMILY SSF161098 6 274 3.08E-75 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS01805 bf5bdd5bb8977a7d5a4b986c7bc621ee 102 SUPERFAMILY SSF143430 1 82 8.76E-15 T 06-07-2017 GTHT12_RS01805 bf5bdd5bb8977a7d5a4b986c7bc621ee 102 Pfam PF09827 CRISPR associated protein Cas2 1 80 2.2E-17 T 06-07-2017 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 GTHT12_RS01805 bf5bdd5bb8977a7d5a4b986c7bc621ee 102 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 100 13.579 T 06-07-2017 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 GTHT12_RS01805 bf5bdd5bb8977a7d5a4b986c7bc621ee 102 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 101 7.7E-26 T 06-07-2017 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 GTHT12_RS16435 b2ec8e45765c9c5f9bf5dec7dbce9a1e 223 Gene3D G3DSA:2.40.260.10 87 215 3.0E-25 T 06-07-2017 IPR023365 Sortase domain GTHT12_RS16435 b2ec8e45765c9c5f9bf5dec7dbce9a1e 223 Pfam PF04203 Sortase family 91 211 9.2E-25 T 06-07-2017 IPR005754 Sortase family GTHT12_RS16435 b2ec8e45765c9c5f9bf5dec7dbce9a1e 223 TIGRFAM TIGR01076 sortase_fam: sortase 89 212 7.1E-27 T 06-07-2017 IPR005754 Sortase family GTHT12_RS16435 b2ec8e45765c9c5f9bf5dec7dbce9a1e 223 SUPERFAMILY SSF63817 81 213 2.35E-32 T 06-07-2017 IPR023365 Sortase domain GTHT12_RS10515 1f2871ff324ba8d10ee3434e166e6523 427 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 419 3.3E-153 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 GTHT12_RS10515 1f2871ff324ba8d10ee3434e166e6523 427 PIRSF PIRSF006066 1 426 1.3E-152 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 GTHT12_RS10515 1f2871ff324ba8d10ee3434e166e6523 427 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 8 415 2.0E-126 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit GTHT12_RS11940 12a50311256ca2151242e051db8a4faa 138 Gene3D G3DSA:3.40.50.300 83 138 2.6E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11940 12a50311256ca2151242e051db8a4faa 138 SUPERFAMILY SSF52540 65 138 1.17E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11940 12a50311256ca2151242e051db8a4faa 138 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 83 135 1.2E-7 T 06-07-2017 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 GTHT12_RS02915 5d36637210ca6ae55e2dad8360d56ba1 111 Gene3D G3DSA:2.30.30.340 55 107 2.6E-25 T 06-07-2017 GTHT12_RS02915 5d36637210ca6ae55e2dad8360d56ba1 111 Gene3D G3DSA:1.10.287.880 4 54 9.9E-28 T 06-07-2017 GTHT12_RS02915 5d36637210ca6ae55e2dad8360d56ba1 111 SUPERFAMILY SSF101697 5 108 2.35E-48 T 06-07-2017 IPR014938 Protein of unknown function DUF1811 GTHT12_RS02915 5d36637210ca6ae55e2dad8360d56ba1 111 Pfam PF08838 Protein of unknown function (DUF1811) 7 105 1.9E-45 T 06-07-2017 IPR014938 Protein of unknown function DUF1811 GTHT12_RS05045 6ce0fb23183ecffb6aea41ab3a9a7686 413 Gene3D G3DSA:3.30.70.150 1 120 1.6E-35 T 06-07-2017 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 GTHT12_RS05045 6ce0fb23183ecffb6aea41ab3a9a7686 413 Hamap MF_01679 2,3-diketo-5-methylthiopentyl-1-phosphate enolase [mtnW]. 2 407 62.161 T 06-07-2017 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 GTHT12_RS05045 6ce0fb23183ecffb6aea41ab3a9a7686 413 SUPERFAMILY SSF51649 121 409 9.03E-88 T 06-07-2017 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 GTHT12_RS05045 6ce0fb23183ecffb6aea41ab3a9a7686 413 Gene3D G3DSA:3.20.20.110 121 410 6.2E-75 T 06-07-2017 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 GTHT12_RS05045 6ce0fb23183ecffb6aea41ab3a9a7686 413 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 4 100 2.3E-6 T 06-07-2017 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 GTHT12_RS05045 6ce0fb23183ecffb6aea41ab3a9a7686 413 SUPERFAMILY SSF54966 1 120 1.96E-32 T 06-07-2017 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 GTHT12_RS05045 6ce0fb23183ecffb6aea41ab3a9a7686 413 TIGRFAM TIGR03332 salvage_mtnW: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase 2 407 1.6E-226 T 06-07-2017 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 GTHT12_RS05045 6ce0fb23183ecffb6aea41ab3a9a7686 413 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 126 406 1.7E-42 T 06-07-2017 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 GTHT12_RS07435 c5d62efb950bdff91da4005f155ebbe5 191 Gene3D G3DSA:2.40.440.10 18 107 8.8E-5 T 06-07-2017 GTHT12_RS07435 c5d62efb950bdff91da4005f155ebbe5 191 Gene3D G3DSA:2.40.440.10 143 178 8.8E-5 T 06-07-2017 GTHT12_RS07435 c5d62efb950bdff91da4005f155ebbe5 191 Pfam PF03734 L,D-transpeptidase catalytic domain 16 182 4.3E-14 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 GTHT12_RS04215 f8c4c5f6bc91c99da1548553451daaf2 386 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 1 378 46.146 T 06-07-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 GTHT12_RS04215 f8c4c5f6bc91c99da1548553451daaf2 386 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 204 241 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GTHT12_RS04215 f8c4c5f6bc91c99da1548553451daaf2 386 SUPERFAMILY SSF53383 3 378 5.36E-132 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS04215 f8c4c5f6bc91c99da1548553451daaf2 386 Gene3D G3DSA:3.40.640.10 48 283 4.5E-93 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS04215 f8c4c5f6bc91c99da1548553451daaf2 386 Pfam PF00202 Aminotransferase class-III 12 377 1.4E-123 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GTHT12_RS04215 f8c4c5f6bc91c99da1548553451daaf2 386 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 5 377 1.8E-151 T 06-07-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 GTHT12_RS04215 f8c4c5f6bc91c99da1548553451daaf2 386 Gene3D G3DSA:3.90.1150.10 288 378 2.3E-36 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS04215 f8c4c5f6bc91c99da1548553451daaf2 386 Gene3D G3DSA:3.90.1150.10 3 47 2.3E-36 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS10565 0da38957a1547478e7897cc8df1dae0e 101 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 3 90 1.5E-23 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 GTHT12_RS10565 0da38957a1547478e7897cc8df1dae0e 101 Gene3D G3DSA:3.30.1360.20 2 94 2.9E-27 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 GTHT12_RS10565 0da38957a1547478e7897cc8df1dae0e 101 SUPERFAMILY SSF55248 2 94 3.14E-27 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 GTHT12_RS01090 9b8f2b32bc013864299aa3a03579aebc 159 Pfam PF11188 Protein of unknown function (DUF2975) 35 159 1.9E-35 T 06-07-2017 IPR021354 Protein of unknown function DUF2975 GTHT12_RS02320 6d42e7e229b86da88120a653cde8e5ba 342 Pfam PF13478 XdhC Rossmann domain 194 329 1.7E-28 T 06-07-2017 IPR027051 XdhC Rossmann domain GTHT12_RS02320 6d42e7e229b86da88120a653cde8e5ba 342 Pfam PF02625 XdhC and CoxI family 14 72 1.2E-12 T 06-07-2017 IPR003777 XdhC- CoxI GTHT12_RS12530 4e1fcfef88ef79c8e298c022cf53e317 448 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 7 357 5.2E-145 T 06-07-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 GTHT12_RS12530 4e1fcfef88ef79c8e298c022cf53e317 448 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 3 441 31.172 T 06-07-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 GTHT12_RS12530 4e1fcfef88ef79c8e298c022cf53e317 448 Pfam PF02601 Exonuclease VII, large subunit 124 438 1.1E-106 T 06-07-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 GTHT12_RS12530 4e1fcfef88ef79c8e298c022cf53e317 448 Pfam PF13742 OB-fold nucleic acid binding domain 7 101 3.6E-31 T 06-07-2017 IPR025824 OB-fold nucleic acid binding domain GO:0003676 GTHT12_RS14015 3556f25c29b78344e8b9d69224572003 257 SUPERFAMILY SSF52096 1 257 7.17E-91 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS14015 3556f25c29b78344e8b9d69224572003 257 Gene3D G3DSA:3.90.226.10 1 255 5.7E-94 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS14015 3556f25c29b78344e8b9d69224572003 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 GTHT12_RS14015 3556f25c29b78344e8b9d69224572003 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 256 2.0E-66 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 GTHT12_RS01770 738825bf269ed215fdb7f518f1fa248f 262 TIGRFAM TIGR03733 lanti_perm_MutG: lantibiotic protection ABC transporter permease subunit, MutG family 5 259 3.2E-91 T 06-07-2017 IPR022294 Lantibiotic protection ABC transporter permease subunit, MutG family GTHT12_RS01770 738825bf269ed215fdb7f518f1fa248f 262 Pfam PF12730 ABC-2 family transporter protein 6 161 1.3E-13 T 06-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 GTHT12_RS11915 2c4e67d1e6b4975e74c5c59ceb4c23dc 368 ProDom PD136539 TRANSCRIPTION SIGMA-X NEGATIVE ACTIVITY RSIX REPRESSOR MEMBRANE EFFECTOR REGULATION REGULATOR 1 359 6.0E-101 T 06-07-2017 GTHT12_RS11915 2c4e67d1e6b4975e74c5c59ceb4c23dc 368 Pfam PF10646 Sporulation and spore germination 240 340 1.3E-4 T 06-07-2017 IPR019606 GerMN domain GTHT12_RS00995 88ad8daa39c9dad065980e72ef796424 159 SMART SM00903 10 157 2.0E-35 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 GTHT12_RS00995 88ad8daa39c9dad065980e72ef796424 159 Gene3D G3DSA:2.30.110.10 7 156 3.9E-42 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 GTHT12_RS00995 88ad8daa39c9dad065980e72ef796424 159 Pfam PF01613 Flavin reductase like domain 11 152 1.4E-25 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 GTHT12_RS00995 88ad8daa39c9dad065980e72ef796424 159 SUPERFAMILY SSF50475 1 157 8.83E-41 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 GTHT12_RS09720 a2be374abe33e22c147a16780f4b74d6 308 Pfam PF04231 Endonuclease I 152 295 1.4E-30 T 06-07-2017 IPR007346 Endonuclease I GO:0004518 GTHT12_RS09720 a2be374abe33e22c147a16780f4b74d6 308 SUPERFAMILY SSF54060 103 295 7.89E-45 T 06-07-2017 GTHT12_RS03470 84c98d7f42aad53da66f53a71c37a2e3 178 Gene3D G3DSA:1.20.120.450 5 178 1.4E-58 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase GTHT12_RS03470 84c98d7f42aad53da66f53a71c37a2e3 178 SUPERFAMILY SSF109854 8 178 8.24E-46 T 06-07-2017 GTHT12_RS03470 84c98d7f42aad53da66f53a71c37a2e3 178 Hamap MF_01256 Putative metal-dependent hydrolase . 5 178 37.668 T 06-07-2017 IPR023774 Putative metal-dependent hydrolase YfiT GTHT12_RS03470 84c98d7f42aad53da66f53a71c37a2e3 178 Pfam PF12867 DinB superfamily 33 169 4.8E-16 T 06-07-2017 IPR024775 DinB-like domain GTHT12_RS09875 56f393e2cb5d65b40d16ad1ec02532f6 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 289 2.7E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS09875 56f393e2cb5d65b40d16ad1ec02532f6 296 SUPERFAMILY SSF161098 12 295 2.22E-54 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS09875 56f393e2cb5d65b40d16ad1ec02532f6 296 Gene3D G3DSA:1.10.3720.10 11 283 1.7E-45 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS04130 72d19d481048c15653103337ad7383b7 186 SUPERFAMILY SSF89155 6 161 9.29E-25 T 06-07-2017 IPR020945 DMSO/Nitrate reductase chaperone GTHT12_RS04130 72d19d481048c15653103337ad7383b7 186 Pfam PF02613 Nitrate reductase delta subunit 44 155 1.2E-8 T 06-07-2017 IPR020945 DMSO/Nitrate reductase chaperone GTHT12_RS04130 72d19d481048c15653103337ad7383b7 186 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 12 157 1.8E-34 T 06-07-2017 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 GTHT12_RS04130 72d19d481048c15653103337ad7383b7 186 Gene3D G3DSA:1.10.3480.10 11 128 3.2E-5 T 06-07-2017 IPR020945 DMSO/Nitrate reductase chaperone GTHT12_RS00365 8257f8dda19a20c1f8675b3ce0b1d10a 325 Gene3D G3DSA:1.10.510.10 143 241 4.4E-7 T 06-07-2017 GTHT12_RS00365 8257f8dda19a20c1f8675b3ce0b1d10a 325 SUPERFAMILY SSF56112 13 236 1.07E-23 T 06-07-2017 IPR011009 Protein kinase-like domain GTHT12_RS00365 8257f8dda19a20c1f8675b3ce0b1d10a 325 Pfam PF00069 Protein kinase domain 29 234 1.5E-11 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 GTHT12_RS00365 8257f8dda19a20c1f8675b3ce0b1d10a 325 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 35 56 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 GTHT12_RS00365 8257f8dda19a20c1f8675b3ce0b1d10a 325 SMART SM00220 29 266 2.0E-6 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 GTHT12_RS00365 8257f8dda19a20c1f8675b3ce0b1d10a 325 Gene3D G3DSA:3.30.200.20 24 142 1.5E-12 T 06-07-2017 GTHT12_RS10215 aeb72c97c58c9cb95ab7efa1ee965949 331 SUPERFAMILY SSF53613 6 323 7.48E-83 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS10215 aeb72c97c58c9cb95ab7efa1ee965949 331 Pfam PF00294 pfkB family carbohydrate kinase 8 312 9.8E-61 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB GTHT12_RS10215 aeb72c97c58c9cb95ab7efa1ee965949 331 Gene3D G3DSA:3.40.1190.20 6 326 7.4E-93 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS10215 aeb72c97c58c9cb95ab7efa1ee965949 331 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 257 270 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 GTHT12_RS08185 a7dbd8a1c162f31ef6553f32e7e14b54 454 Pfam PF01554 MatE 20 180 3.1E-32 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 GTHT12_RS08185 a7dbd8a1c162f31ef6553f32e7e14b54 454 Pfam PF01554 MatE 246 405 1.9E-34 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 GTHT12_RS08185 a7dbd8a1c162f31ef6553f32e7e14b54 454 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 420 4.7E-92 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 GTHT12_RS08185 a7dbd8a1c162f31ef6553f32e7e14b54 454 PIRSF PIRSF006603 7 450 1.8E-62 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 GTHT12_RS03500 b3a732cf192865dfb5d65b7b27fc7f25 203 Gene3D G3DSA:3.20.20.70 4 198 3.2E-52 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS03500 b3a732cf192865dfb5d65b7b27fc7f25 203 SUPERFAMILY SSF51391 17 197 3.92E-49 T 06-07-2017 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GTHT12_RS03500 b3a732cf192865dfb5d65b7b27fc7f25 203 Pfam PF02581 Thiamine monophosphate synthase/TENI 13 180 6.3E-42 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GTHT12_RS07060 ab8174993c0d901cc0d7c6a238151865 138 Pfam PF03061 Thioesterase superfamily 50 124 4.9E-11 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 GTHT12_RS07060 ab8174993c0d901cc0d7c6a238151865 138 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 23 132 2.7E-13 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 GTHT12_RS07060 ab8174993c0d901cc0d7c6a238151865 138 Gene3D G3DSA:3.10.129.10 17 137 7.0E-29 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS07060 ab8174993c0d901cc0d7c6a238151865 138 SUPERFAMILY SSF54637 6 134 4.43E-26 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS12505 3a0364eb8ddb5c31f14ab7b7b2c21f46 281 Gene3D G3DSA:3.10.290.10 6 91 1.7E-20 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS12505 3a0364eb8ddb5c31f14ab7b7b2c21f46 281 SUPERFAMILY SSF55174 5 71 4.42E-12 T 06-07-2017 GTHT12_RS12505 3a0364eb8ddb5c31f14ab7b7b2c21f46 281 PIRSF PIRSF005578 1 267 1.0E-105 T 06-07-2017 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 GTHT12_RS12505 3a0364eb8ddb5c31f14ab7b7b2c21f46 281 Pfam PF01479 S4 domain 6 48 2.9E-9 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS12505 3a0364eb8ddb5c31f14ab7b7b2c21f46 281 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 7 239 4.7E-93 T 06-07-2017 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 GTHT12_RS12505 3a0364eb8ddb5c31f14ab7b7b2c21f46 281 Pfam PF01728 FtsJ-like methyltransferase 62 243 1.3E-19 T 06-07-2017 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 GTHT12_RS12505 3a0364eb8ddb5c31f14ab7b7b2c21f46 281 SUPERFAMILY SSF53335 61 244 2.1E-23 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS12505 3a0364eb8ddb5c31f14ab7b7b2c21f46 281 SMART SM00363 6 71 4.3E-9 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 GTHT12_RS12505 3a0364eb8ddb5c31f14ab7b7b2c21f46 281 Gene3D G3DSA:3.40.50.150 92 226 3.3E-5 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS15315 2d8c6184e2272847a6279c8d08b16d6f 386 SUPERFAMILY SSF53383 1 382 6.52E-99 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS15315 2d8c6184e2272847a6279c8d08b16d6f 386 Gene3D G3DSA:3.40.640.10 43 251 6.6E-49 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS15315 2d8c6184e2272847a6279c8d08b16d6f 386 Pfam PF00155 Aminotransferase class I and II 42 381 3.0E-38 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 GTHT12_RS15315 2d8c6184e2272847a6279c8d08b16d6f 386 Gene3D G3DSA:3.90.1150.10 252 385 1.7E-38 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS15315 2d8c6184e2272847a6279c8d08b16d6f 386 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 4 385 9.6E-149 T 06-07-2017 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 GTHT12_RS00035 fc421ab20a2019ef0226a71c3b030df7 353 Pfam PF13487 HD domain 188 246 5.9E-14 T 06-07-2017 GTHT12_RS00035 fc421ab20a2019ef0226a71c3b030df7 353 Gene3D G3DSA:1.10.3210.10 126 290 6.8E-15 T 06-07-2017 IPR006674 HD domain GTHT12_RS00035 fc421ab20a2019ef0226a71c3b030df7 353 SUPERFAMILY SSF109604 126 296 8.28E-25 T 06-07-2017 GTHT12_RS05900 4128fc773a8e8501b18e9fdd499ffa86 120 Pfam PF06947 Protein of unknown function (DUF1290) 22 106 7.7E-36 T 06-07-2017 IPR009709 Protein of unknown function DUF1290 GTHT12_RS05900 4128fc773a8e8501b18e9fdd499ffa86 120 PIRSF PIRSF018579 1 113 2.0E-43 T 06-07-2017 IPR009709 Protein of unknown function DUF1290 GTHT12_RS18665 2a5b043dc151018530229d4c5aa89e1f 156 SUPERFAMILY SSF55166 16 133 4.71E-32 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 GTHT12_RS18665 2a5b043dc151018530229d4c5aa89e1f 156 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 68 133 4.3E-18 T 06-07-2017 GTHT12_RS00930 0543d9100a73a75f3961f362443180a2 273 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 3 254 4.7E-101 T 06-07-2017 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 GTHT12_RS00930 0543d9100a73a75f3961f362443180a2 273 SUPERFAMILY SSF143597 40 240 3.27E-74 T 06-07-2017 GTHT12_RS00930 0543d9100a73a75f3961f362443180a2 273 PIRSF PIRSF004793 3 269 6.2E-98 T 06-07-2017 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 GTHT12_RS00930 0543d9100a73a75f3961f362443180a2 273 Gene3D G3DSA:3.40.1700.10 112 240 5.0E-57 T 06-07-2017 GTHT12_RS00930 0543d9100a73a75f3961f362443180a2 273 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 118 236 1.1E-45 T 06-07-2017 IPR003390 DNA integrity scanning protein, DisA, N-terminal GTHT12_RS11810 db15d7e3e0ab5ae84658d0ba9b1b6c88 447 TIGRFAM TIGR02889 spore_YpeB: germination protein YpeB 3 439 3.7E-139 T 06-07-2017 IPR014239 Spore germination YpeB GO:0009847 GTHT12_RS11810 db15d7e3e0ab5ae84658d0ba9b1b6c88 447 Pfam PF14620 YpeB sporulation 13 373 3.3E-132 T 06-07-2017 IPR014239 Spore germination YpeB GO:0009847 GTHT12_RS14900 efca5913cf8141ef179f18b8f79532c4 458 SUPERFAMILY SSF56322 44 453 1.16E-107 T 06-07-2017 IPR005801 ADC synthase GO:0009058 GTHT12_RS14900 efca5913cf8141ef179f18b8f79532c4 458 Pfam PF00425 chorismate binding enzyme 191 444 5.3E-78 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal GTHT12_RS14900 efca5913cf8141ef179f18b8f79532c4 458 Gene3D G3DSA:3.60.120.10 56 454 3.1E-102 T 06-07-2017 IPR005801 ADC synthase GO:0009058 GTHT12_RS14900 efca5913cf8141ef179f18b8f79532c4 458 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 106 452 6.5E-111 T 06-07-2017 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 GTHT12_RS05715 9e20ea81e0afa7c6aaf72aed729a7bc6 300 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 27 282 5.9E-65 T 06-07-2017 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related GTHT12_RS05715 9e20ea81e0afa7c6aaf72aed729a7bc6 300 TIGRFAM TIGR02737 caa3_CtaG: cytochrome c oxidase assembly factor CtaG 5 284 3.8E-134 T 06-07-2017 IPR014108 Cytochrome c oxidase caa3 type assembly factor CtaG GTHT12_RS09825 89f09913592296974ca980d5456f28f1 407 ProSitePatterns PS00591 Glycosyl hydrolases family 10 (GH10) active site. 286 296 - T 06-07-2017 IPR031158 Glycosyl hydrolases family 10, active site MetaCyc: PWY-6784 GTHT12_RS09825 89f09913592296974ca980d5456f28f1 407 SMART SM00633 89 407 3.3E-145 T 06-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 GTHT12_RS09825 89f09913592296974ca980d5456f28f1 407 SUPERFAMILY SSF51445 44 405 4.15E-103 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS09825 89f09913592296974ca980d5456f28f1 407 Pfam PF00331 Glycosyl hydrolase family 10 48 405 7.5E-106 T 06-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 GTHT12_RS09825 89f09913592296974ca980d5456f28f1 407 Gene3D G3DSA:3.20.20.80 45 405 1.6E-114 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS09825 89f09913592296974ca980d5456f28f1 407 PRINTS PR00134 Glycosyl hydrolase family 10 signature 120 132 1.5E-16 T 06-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 GTHT12_RS09825 89f09913592296974ca980d5456f28f1 407 PRINTS PR00134 Glycosyl hydrolase family 10 signature 224 235 1.5E-16 T 06-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 GTHT12_RS09825 89f09913592296974ca980d5456f28f1 407 PRINTS PR00134 Glycosyl hydrolase family 10 signature 252 264 1.5E-16 T 06-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 GTHT12_RS09825 89f09913592296974ca980d5456f28f1 407 PRINTS PR00134 Glycosyl hydrolase family 10 signature 179 190 1.5E-16 T 06-07-2017 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 GTHT12_RS01600 79e52cc00cad038e12c535e833076cd8 431 PRINTS PR00145 Argininosuccinate lyase family signature 87 109 1.3E-8 T 06-07-2017 GTHT12_RS01600 79e52cc00cad038e12c535e833076cd8 431 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 1.3E-8 T 06-07-2017 GTHT12_RS01600 79e52cc00cad038e12c535e833076cd8 431 PRINTS PR00145 Argininosuccinate lyase family signature 128 148 1.3E-8 T 06-07-2017 GTHT12_RS01600 79e52cc00cad038e12c535e833076cd8 431 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 1.3E-8 T 06-07-2017 GTHT12_RS01600 79e52cc00cad038e12c535e833076cd8 431 SUPERFAMILY SSF48557 3 426 4.71E-142 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 GTHT12_RS01600 79e52cc00cad038e12c535e833076cd8 431 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 GTHT12_RS01600 79e52cc00cad038e12c535e833076cd8 431 Gene3D G3DSA:1.10.40.30 357 428 1.6E-36 T 06-07-2017 GTHT12_RS01600 79e52cc00cad038e12c535e833076cd8 431 SMART SM00998 349 429 2.8E-43 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GTHT12_RS01600 79e52cc00cad038e12c535e833076cd8 431 Gene3D G3DSA:1.10.275.10 2 90 3.2E-37 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal GTHT12_RS01600 79e52cc00cad038e12c535e833076cd8 431 Gene3D G3DSA:1.20.200.10 91 356 2.5E-94 T 06-07-2017 GTHT12_RS01600 79e52cc00cad038e12c535e833076cd8 431 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 427 5.3E-28 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GTHT12_RS01600 79e52cc00cad038e12c535e833076cd8 431 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 428 7.9E-184 T 06-07-2017 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 GTHT12_RS01600 79e52cc00cad038e12c535e833076cd8 431 PRINTS PR00149 Fumarate lyase superfamily signature 88 106 8.7E-26 T 06-07-2017 IPR000362 Fumarate lyase family GTHT12_RS01600 79e52cc00cad038e12c535e833076cd8 431 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 8.7E-26 T 06-07-2017 IPR000362 Fumarate lyase family GTHT12_RS01600 79e52cc00cad038e12c535e833076cd8 431 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 8.7E-26 T 06-07-2017 IPR000362 Fumarate lyase family GTHT12_RS01600 79e52cc00cad038e12c535e833076cd8 431 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 8.7E-26 T 06-07-2017 IPR000362 Fumarate lyase family GTHT12_RS01600 79e52cc00cad038e12c535e833076cd8 431 Pfam PF00206 Lyase 6 286 3.1E-77 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal GTHT12_RS06355 6410cb31d1a2ba1264d47be20967d0ee 203 Pfam PF03448 MgtE intracellular N domain 134 193 3.2E-9 T 06-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain GTHT12_RS06355 6410cb31d1a2ba1264d47be20967d0ee 203 Gene3D G3DSA:1.25.60.10 95 194 1.4E-8 T 06-07-2017 GTHT12_RS06355 6410cb31d1a2ba1264d47be20967d0ee 203 SUPERFAMILY SSF158791 133 193 4.32E-9 T 06-07-2017 GTHT12_RS01815 5708755c8f8607ca58c287446fb48db5 1082 TIGRFAM TIGR01865 cas_Csn1: CRISPR subtype II RNA-guided endonuclease Cas9 2 747 2.8E-173 T 06-07-2017 IPR028629 CRISPR-associated endonuclease Cas9 GO:0004519 GTHT12_RS01815 5708755c8f8607ca58c287446fb48db5 1082 Hamap MF_01480 CRISPR-associated endonuclease Cas9 [cas9]. 1 1060 19.581 T 06-07-2017 IPR028629 CRISPR-associated endonuclease Cas9 GO:0004519 GTHT12_RS01815 5708755c8f8607ca58c287446fb48db5 1082 Pfam PF13395 HNH endonuclease 560 613 1.6E-20 T 06-07-2017 IPR003615 HNH nuclease GTHT12_RS12340 b995ae5e0fee5cc83d63af2a810ede9a 391 Gene3D G3DSA:3.90.230.10 159 389 1.8E-45 T 06-07-2017 IPR000994 Peptidase M24, structural domain GTHT12_RS12340 b995ae5e0fee5cc83d63af2a810ede9a 391 Gene3D G3DSA:3.40.350.10 1 156 1.7E-36 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal GTHT12_RS12340 b995ae5e0fee5cc83d63af2a810ede9a 391 Pfam PF01321 Creatinase/Prolidase N-terminal domain 12 156 4.2E-20 T 06-07-2017 IPR000587 Creatinase, N-terminal GO:0016787 GTHT12_RS12340 b995ae5e0fee5cc83d63af2a810ede9a 391 Pfam PF00557 Metallopeptidase family M24 166 375 2.6E-35 T 06-07-2017 IPR000994 Peptidase M24, structural domain GTHT12_RS12340 b995ae5e0fee5cc83d63af2a810ede9a 391 SUPERFAMILY SSF55920 159 390 4.45E-56 T 06-07-2017 IPR000994 Peptidase M24, structural domain GTHT12_RS12340 b995ae5e0fee5cc83d63af2a810ede9a 391 SUPERFAMILY SSF53092 1 156 9.42E-37 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal GTHT12_RS16250 6db7b0abddfffcc2ff5206d53eba2858 145 Pfam PF03885 Protein of unknown function (DUF327) 14 144 6.8E-41 T 06-07-2017 IPR005585 Protein of unknown function DUF327 GTHT12_RS16250 6db7b0abddfffcc2ff5206d53eba2858 145 SUPERFAMILY SSF158397 26 145 4.32E-36 T 06-07-2017 GTHT12_RS16250 6db7b0abddfffcc2ff5206d53eba2858 145 Gene3D G3DSA:1.20.120.490 26 145 2.7E-40 T 06-07-2017 IPR024042 Hypothetical protein TM1646-like domain GTHT12_RS06390 795ded6b4ba3063da14e143ebd5d1e6a 394 PRINTS PR00956 Flagellar motor switch protein FliN signature 314 330 1.6E-28 T 06-07-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 GTHT12_RS06390 795ded6b4ba3063da14e143ebd5d1e6a 394 PRINTS PR00956 Flagellar motor switch protein FliN signature 331 347 1.6E-28 T 06-07-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 GTHT12_RS06390 795ded6b4ba3063da14e143ebd5d1e6a 394 PRINTS PR00956 Flagellar motor switch protein FliN signature 360 375 1.6E-28 T 06-07-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 GTHT12_RS06390 795ded6b4ba3063da14e143ebd5d1e6a 394 PRINTS PR00956 Flagellar motor switch protein FliN signature 347 360 1.6E-28 T 06-07-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 GTHT12_RS06390 795ded6b4ba3063da14e143ebd5d1e6a 394 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 311 386 3.4E-32 T 06-07-2017 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 GTHT12_RS06390 795ded6b4ba3063da14e143ebd5d1e6a 394 Pfam PF04509 CheC-like family 36 71 3.2E-14 T 06-07-2017 IPR007597 CheC-like protein GO:0016787 GTHT12_RS06390 795ded6b4ba3063da14e143ebd5d1e6a 394 Pfam PF04509 CheC-like family 132 168 4.5E-16 T 06-07-2017 IPR007597 CheC-like protein GO:0016787 GTHT12_RS06390 795ded6b4ba3063da14e143ebd5d1e6a 394 SUPERFAMILY SSF101801 310 393 3.01E-26 T 06-07-2017 IPR001543 Surface presentation of antigen (SpoA) GTHT12_RS06390 795ded6b4ba3063da14e143ebd5d1e6a 394 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 315 384 4.4E-26 T 06-07-2017 IPR001543 Surface presentation of antigen (SpoA) GTHT12_RS06390 795ded6b4ba3063da14e143ebd5d1e6a 394 Gene3D G3DSA:2.30.330.10 306 394 1.1E-37 T 06-07-2017 GTHT12_RS06390 795ded6b4ba3063da14e143ebd5d1e6a 394 SUPERFAMILY SSF103039 30 220 6.71E-51 T 06-07-2017 IPR028976 CheC-like domain GTHT12_RS06390 795ded6b4ba3063da14e143ebd5d1e6a 394 Gene3D G3DSA:3.40.1550.10 32 220 7.4E-66 T 06-07-2017 IPR028976 CheC-like domain GTHT12_RS08955 476b8cc7bafa100ff1d097d5a177a5f3 90 Pfam PF13791 Sigma factor regulator C-terminal 15 88 7.6E-14 T 06-07-2017 IPR025672 Sigma factor regulator C-terminal domain GTHT12_RS10590 a0d2ec01ac55eef7d2df6e12d735bdd9 272 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 44 222 4.3E-15 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain GTHT12_RS10590 a0d2ec01ac55eef7d2df6e12d735bdd9 272 Gene3D G3DSA:3.40.50.1110 40 264 5.8E-79 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain GTHT12_RS10590 a0d2ec01ac55eef7d2df6e12d735bdd9 272 SUPERFAMILY SSF52266 41 261 2.75E-51 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain GTHT12_RS03770 76d8bc466652fe0142e0a253ae372b72 182 PIRSF PIRSF011560 5 181 8.1E-58 T 06-07-2017 IPR010461 Competence protein ComK GO:0030420 GTHT12_RS03770 76d8bc466652fe0142e0a253ae372b72 182 Pfam PF06338 ComK protein 10 158 2.2E-56 T 06-07-2017 IPR010461 Competence protein ComK GO:0030420 GTHT12_RS15805 e5e651834becf426201b2169a18ce7c6 260 SUPERFAMILY SSF56529 45 252 6.41E-51 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GTHT12_RS15805 e5e651834becf426201b2169a18ce7c6 260 Gene3D G3DSA:3.90.850.10 45 255 1.0E-46 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GTHT12_RS15805 e5e651834becf426201b2169a18ce7c6 260 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 48 251 3.3E-41 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GTHT12_RS00950 ea6d17b9b590b65d5a94f8f943225cc9 278 Gene3D G3DSA:3.30.460.10 25 141 5.7E-7 T 06-07-2017 GTHT12_RS00950 ea6d17b9b590b65d5a94f8f943225cc9 278 Pfam PF04439 Streptomycin adenylyltransferase 17 271 1.2E-5 T 06-07-2017 IPR007530 Aminoglycoside 6-adenylyltransferase GTHT12_RS00950 ea6d17b9b590b65d5a94f8f943225cc9 278 SUPERFAMILY SSF81301 17 137 7.01E-9 T 06-07-2017 GTHT12_RS04825 8b2143bfe3da79771e1b04c6ee4ca2c4 263 PIRSF PIRSF006648 1 263 7.3E-76 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 GTHT12_RS04825 8b2143bfe3da79771e1b04c6ee4ca2c4 263 Pfam PF01061 ABC-2 type transporter 20 226 5.7E-34 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 GTHT12_RS04825 8b2143bfe3da79771e1b04c6ee4ca2c4 263 PRINTS PR00164 ABC-2 type transport system membrane protein signature 206 225 3.1E-7 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 GTHT12_RS04825 8b2143bfe3da79771e1b04c6ee4ca2c4 263 PRINTS PR00164 ABC-2 type transport system membrane protein signature 113 138 3.1E-7 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 GTHT12_RS04825 8b2143bfe3da79771e1b04c6ee4ca2c4 263 PRINTS PR00164 ABC-2 type transport system membrane protein signature 186 205 3.1E-7 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 GTHT12_RS03380 ecde0406476524dff60eb0816e091a5e 145 PIRSF PIRSF036659 1 143 2.2E-56 T 06-07-2017 IPR012187 Disulphide bond formation protein BdbC GTHT12_RS03380 ecde0406476524dff60eb0816e091a5e 145 Pfam PF02600 Disulfide bond formation protein DsbB 9 112 2.0E-11 T 06-07-2017 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 GTHT12_RS03380 ecde0406476524dff60eb0816e091a5e 145 Gene3D G3DSA:1.20.1550.10 6 93 6.1E-12 T 06-07-2017 IPR023380 Disulphide bond formation protein DsbB-like domain GTHT12_RS03380 ecde0406476524dff60eb0816e091a5e 145 Hamap MF_00287 Probable disulfide formation protein [bdbC]. 4 140 23.843 T 06-07-2017 IPR012187 Disulphide bond formation protein BdbC GTHT12_RS03380 ecde0406476524dff60eb0816e091a5e 145 SUPERFAMILY SSF158442 11 135 5.1E-30 T 06-07-2017 GTHT12_RS04910 f0a6ba43a36a96da4a8956dd44379e9e 248 Pfam PF06738 Putative threonine/serine exporter 11 247 5.1E-78 T 06-07-2017 IPR010619 Putative threonine/serine exporter GTHT12_RS12580 367baabcd793ce28f7bc58dd6ad2d577 128 Pfam PF06686 Stage III sporulation protein AC/AD protein family 1 54 7.9E-11 T 06-07-2017 IPR025664 Stage III sporulation protein AC/AD family GTHT12_RS12580 367baabcd793ce28f7bc58dd6ad2d577 128 Pfam PF06686 Stage III sporulation protein AC/AD protein family 68 123 7.3E-18 T 06-07-2017 IPR025664 Stage III sporulation protein AC/AD family GTHT12_RS12580 367baabcd793ce28f7bc58dd6ad2d577 128 TIGRFAM TIGR02849 spore_III_AD: stage III sporulation protein AD 24 124 7.4E-35 T 06-07-2017 IPR014211 Stage III sporulation protein AD GTHT12_RS14525 fc9fb567560263091ca9fbf03c18da26 325 Gene3D G3DSA:3.40.50.300 8 54 8.0E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS14525 fc9fb567560263091ca9fbf03c18da26 325 SUPERFAMILY SSF52540 9 113 4.49E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS14525 fc9fb567560263091ca9fbf03c18da26 325 Pfam PF01695 IstB-like ATP binding protein 8 55 1.8E-8 T 06-07-2017 IPR002611 IstB-like ATP-binding protein GO:0005524 GTHT12_RS14525 fc9fb567560263091ca9fbf03c18da26 325 Pfam PF13612 Transposase DDE domain 144 300 6.7E-26 T 06-07-2017 IPR025668 Transposase DDE domain GTHT12_RS08055 8173657366eed6065859328ceed46dfc 138 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 9 122 9.6E-35 T 06-07-2017 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 GTHT12_RS08055 8173657366eed6065859328ceed46dfc 138 Pfam PF03061 Thioesterase superfamily 18 101 1.2E-14 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 GTHT12_RS08055 8173657366eed6065859328ceed46dfc 138 PIRSF PIRSF003230 1 136 2.4E-34 T 06-07-2017 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 GTHT12_RS08055 8173657366eed6065859328ceed46dfc 138 SUPERFAMILY SSF54637 3 133 2.69E-42 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS08055 8173657366eed6065859328ceed46dfc 138 Gene3D G3DSA:3.10.129.10 3 135 1.2E-45 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS04270 92d04b835aedc30a3250ce2b087c952f 310 Gene3D G3DSA:3.40.47.10 1 158 1.8E-66 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS04270 92d04b835aedc30a3250ce2b087c952f 310 SUPERFAMILY SSF53901 4 308 1.02E-71 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS04270 92d04b835aedc30a3250ce2b087c952f 310 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 308 72.863 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 GTHT12_RS04270 92d04b835aedc30a3250ce2b087c952f 310 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 184 6.8E-31 T 06-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 GTHT12_RS04270 92d04b835aedc30a3250ce2b087c952f 310 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 219 308 3.8E-36 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 GTHT12_RS04270 92d04b835aedc30a3250ce2b087c952f 310 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 1 308 2.2E-134 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 GTHT12_RS04270 92d04b835aedc30a3250ce2b087c952f 310 Gene3D G3DSA:3.40.47.10 159 308 3.1E-54 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 GTHT12_RS02640 56e32a8e6e3687bd459cdbe206a102bf 1479 SUPERFAMILY SSF52540 949 1162 3.09E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS02640 56e32a8e6e3687bd459cdbe206a102bf 1479 SUPERFAMILY SSF52540 633 891 2.56E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS02640 56e32a8e6e3687bd459cdbe206a102bf 1479 Pfam PF12538 DNA transporter 3 117 6.2E-21 T 06-07-2017 IPR022206 Firmicutes EssC, N-terminal GTHT12_RS02640 56e32a8e6e3687bd459cdbe206a102bf 1479 Pfam PF01580 FtsK/SpoIIIE family 640 852 9.5E-32 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 GTHT12_RS02640 56e32a8e6e3687bd459cdbe206a102bf 1479 Pfam PF01580 FtsK/SpoIIIE family 983 1153 1.7E-19 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 GTHT12_RS02640 56e32a8e6e3687bd459cdbe206a102bf 1479 SUPERFAMILY SSF52540 1232 1416 7.89E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS02640 56e32a8e6e3687bd459cdbe206a102bf 1479 SMART SM00382 1276 1442 5.3 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS02640 56e32a8e6e3687bd459cdbe206a102bf 1479 SMART SM00382 993 1163 4.5 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS02640 56e32a8e6e3687bd459cdbe206a102bf 1479 SMART SM00382 664 845 0.34 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS02640 56e32a8e6e3687bd459cdbe206a102bf 1479 TIGRFAM TIGR03928 T7_EssCb_Firm: type VII secretion protein EssC 200 1477 0.0 T 06-07-2017 IPR023839 Firmicutes EssC, C-terminal GTHT12_RS02640 56e32a8e6e3687bd459cdbe206a102bf 1479 Gene3D G3DSA:3.40.50.300 985 1161 6.2E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS02640 56e32a8e6e3687bd459cdbe206a102bf 1479 Gene3D G3DSA:3.40.50.300 651 859 3.5E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS02640 56e32a8e6e3687bd459cdbe206a102bf 1479 Gene3D G3DSA:3.40.50.300 1258 1411 1.1E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08465 68c982cc3a91cbec4a8fc6df7ab9c725 265 Gene3D G3DSA:3.40.50.1110 56 257 2.6E-44 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain GTHT12_RS08465 68c982cc3a91cbec4a8fc6df7ab9c725 265 SUPERFAMILY SSF52266 55 257 2.26E-37 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain GTHT12_RS08465 68c982cc3a91cbec4a8fc6df7ab9c725 265 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 61 248 1.7E-26 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain GTHT12_RS09790 387220f062eecd91db33eabde4eb2e23 344 Gene3D G3DSA:3.20.20.70 4 330 1.4E-73 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS09790 387220f062eecd91db33eabde4eb2e23 344 SUPERFAMILY SSF51412 4 342 7.02E-67 T 06-07-2017 GTHT12_RS09790 387220f062eecd91db33eabde4eb2e23 344 Pfam PF03060 Nitronate monooxygenase 7 335 1.5E-105 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 GTHT12_RS10780 69cdf8e3bc20fb1ca59abc955f5300d7 277 PIRSF PIRSF037834 12 277 1.3E-92 T 06-07-2017 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 GTHT12_RS10780 69cdf8e3bc20fb1ca59abc955f5300d7 277 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 30 277 1.1E-67 T 06-07-2017 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 GTHT12_RS10780 69cdf8e3bc20fb1ca59abc955f5300d7 277 SUPERFAMILY SSF47240 21 271 1.3E-58 T 06-07-2017 IPR009078 Ferritin-like superfamily GTHT12_RS10780 69cdf8e3bc20fb1ca59abc955f5300d7 277 Gene3D G3DSA:1.20.1260.10 16 277 1.7E-70 T 06-07-2017 IPR012347 Ferritin-related GTHT12_RS10780 69cdf8e3bc20fb1ca59abc955f5300d7 277 Pfam PF05138 Phenylacetic acid catabolic protein 18 277 2.6E-64 T 06-07-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 GTHT12_RS12415 119603c649fc9638475c71374fc86812 325 SUPERFAMILY SSF51004 16 317 7.59E-36 T 06-07-2017 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain GTHT12_RS12415 119603c649fc9638475c71374fc86812 325 Gene3D G3DSA:2.130.10.10 38 321 2.9E-30 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 GTHT12_RS08010 0c59f4abd3c83e92e7b39576bf961642 192 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 78 166 2.2E-28 T 06-07-2017 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 GTHT12_RS12685 28ccfac714a4ad12f282f6ecc37dd686 99 Pfam PF09862 Protein of unknown function (DUF2089) 8 86 4.1E-15 T 06-07-2017 IPR018658 Protein of unknown function DUF2089 GTHT12_RS00855 d82a6d4b147047711bc5995d8a49b5de 199 PIRSF PIRSF029886 1 197 3.1E-77 T 06-07-2017 IPR024164 KinB-signalling pathway activation protein GO:0045881 GTHT12_RS00855 d82a6d4b147047711bc5995d8a49b5de 199 Pfam PF14089 KinB-signalling pathway activation in sporulation 17 193 3.7E-78 T 06-07-2017 IPR024164 KinB-signalling pathway activation protein GO:0045881 GTHT12_RS00855 d82a6d4b147047711bc5995d8a49b5de 199 SMART SM01251 17 194 7.0E-117 T 06-07-2017 IPR024164 KinB-signalling pathway activation protein GO:0045881 GTHT12_RS09760 440592fc342b3e02afe9fc8d0918693b 110 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 13 106 1.3E-32 T 06-07-2017 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 GTHT12_RS09760 440592fc342b3e02afe9fc8d0918693b 110 SUPERFAMILY SSF46973 8 106 2.22E-32 T 06-07-2017 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 GTHT12_RS09760 440592fc342b3e02afe9fc8d0918693b 110 PIRSF PIRSF000699 5 110 2.3E-34 T 06-07-2017 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 GTHT12_RS09760 440592fc342b3e02afe9fc8d0918693b 110 Gene3D G3DSA:1.20.58.80 10 107 2.5E-33 T 06-07-2017 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 GTHT12_RS01860 e2956ef7966439d316f0d003eeeecb26 412 Gene3D G3DSA:1.20.1250.20 4 194 6.7E-39 T 06-07-2017 GTHT12_RS01860 e2956ef7966439d316f0d003eeeecb26 412 Gene3D G3DSA:1.20.1250.20 206 396 4.7E-30 T 06-07-2017 GTHT12_RS01860 e2956ef7966439d316f0d003eeeecb26 412 PRINTS PR01035 Tetracycline resistance protein signature 105 126 5.1E-5 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS01860 e2956ef7966439d316f0d003eeeecb26 412 PRINTS PR01035 Tetracycline resistance protein signature 345 368 5.1E-5 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS01860 e2956ef7966439d316f0d003eeeecb26 412 PRINTS PR01035 Tetracycline resistance protein signature 135 157 5.1E-5 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS01860 e2956ef7966439d316f0d003eeeecb26 412 PRINTS PR01035 Tetracycline resistance protein signature 16 32 5.1E-5 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 GTHT12_RS01860 e2956ef7966439d316f0d003eeeecb26 412 SUPERFAMILY SSF103473 4 399 4.19E-75 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS01860 e2956ef7966439d316f0d003eeeecb26 412 Pfam PF07690 Major Facilitator Superfamily 10 257 2.1E-35 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS00420 57ad7aa439c22d64e9bc8e99ee66c94a 129 Pfam PF02152 Dihydroneopterin aldolase 14 125 8.4E-37 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 GTHT12_RS00420 57ad7aa439c22d64e9bc8e99ee66c94a 129 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 12 127 5.0E-41 T 06-07-2017 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 GTHT12_RS00420 57ad7aa439c22d64e9bc8e99ee66c94a 129 SMART SM00905 14 127 7.0E-56 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 GTHT12_RS00420 57ad7aa439c22d64e9bc8e99ee66c94a 129 Gene3D G3DSA:3.30.1130.10 12 129 2.5E-45 T 06-07-2017 GTHT12_RS00420 57ad7aa439c22d64e9bc8e99ee66c94a 129 SUPERFAMILY SSF55620 12 129 8.34E-41 T 06-07-2017 GTHT12_RS00420 57ad7aa439c22d64e9bc8e99ee66c94a 129 TIGRFAM TIGR00526 folB_dom: FolB domain 12 128 3.1E-34 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 GTHT12_RS02835 cc37657c88e3790840001b9edb29c2c1 122 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 5 112 2.3E-38 T 06-07-2017 IPR018745 Domain of unknown function DUF2294 GTHT12_RS13175 4b6164419b68e6b478a39ff1c172c03d 44 Pfam PF14141 YqzM-like protein 2 43 1.7E-24 T 06-07-2017 IPR025416 YqzM-like protein GTHT12_RS09370 cbf45f50208781e891979df6f66ff66e 158 Pfam PF00255 Glutathione peroxidase 3 110 2.2E-46 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 GTHT12_RS09370 cbf45f50208781e891979df6f66ff66e 158 Gene3D G3DSA:3.40.30.10 1 158 1.0E-78 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS09370 cbf45f50208781e891979df6f66ff66e 158 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 59 66 - T 06-07-2017 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 GTHT12_RS09370 cbf45f50208781e891979df6f66ff66e 158 PIRSF PIRSF000303 1 158 5.2E-72 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 GTHT12_RS09370 cbf45f50208781e891979df6f66ff66e 158 SUPERFAMILY SSF52833 1 158 2.47E-68 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS09370 cbf45f50208781e891979df6f66ff66e 158 PRINTS PR01011 Glutathione peroxidase family signature 56 72 8.9E-21 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 GTHT12_RS09370 cbf45f50208781e891979df6f66ff66e 158 PRINTS PR01011 Glutathione peroxidase family signature 21 38 8.9E-21 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 GTHT12_RS09370 cbf45f50208781e891979df6f66ff66e 158 PRINTS PR01011 Glutathione peroxidase family signature 122 131 8.9E-21 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 GTHT12_RS13445 38564ae86e339f84b41da7e85d2d278c 253 Pfam PF00899 ThiF family 6 236 3.7E-41 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 GTHT12_RS13445 38564ae86e339f84b41da7e85d2d278c 253 Gene3D G3DSA:3.40.50.720 4 244 1.9E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS13445 38564ae86e339f84b41da7e85d2d278c 253 SUPERFAMILY SSF69572 4 244 3.66E-65 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 GTHT12_RS11755 33c7dc9856c60baacb4f0b5eed5f3f0c 44 Pfam PF14140 YpzI-like protein 2 42 3.8E-25 T 06-07-2017 IPR025414 YpzI-like protein GTHT12_RS18425 7b9ce3a5253cc1f5d0e014a32b1ccf0c 422 SUPERFAMILY SSF51419 18 279 9.01E-58 T 06-07-2017 IPR029066 PLP-binding barrel GTHT12_RS18425 7b9ce3a5253cc1f5d0e014a32b1ccf0c 422 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 284 395 9.9E-11 T 06-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 GTHT12_RS18425 7b9ce3a5253cc1f5d0e014a32b1ccf0c 422 SUPERFAMILY SSF50621 259 401 5.44E-31 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 GTHT12_RS18425 7b9ce3a5253cc1f5d0e014a32b1ccf0c 422 Gene3D G3DSA:3.20.20.10 28 269 4.4E-60 T 06-07-2017 IPR029066 PLP-binding barrel GTHT12_RS18425 7b9ce3a5253cc1f5d0e014a32b1ccf0c 422 Gene3D G3DSA:2.40.37.10 270 416 2.7E-30 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 GTHT12_RS18425 7b9ce3a5253cc1f5d0e014a32b1ccf0c 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 375 388 3.3E-14 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 GTHT12_RS18425 7b9ce3a5253cc1f5d0e014a32b1ccf0c 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 48 66 3.3E-14 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 GTHT12_RS18425 7b9ce3a5253cc1f5d0e014a32b1ccf0c 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 68 80 3.3E-14 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 GTHT12_RS18425 7b9ce3a5253cc1f5d0e014a32b1ccf0c 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 181 194 3.3E-14 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 GTHT12_RS18425 7b9ce3a5253cc1f5d0e014a32b1ccf0c 422 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 269 288 3.3E-14 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 GTHT12_RS18425 7b9ce3a5253cc1f5d0e014a32b1ccf0c 422 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 31 279 1.4E-41 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 GTHT12_RS08325 ef79b46f6a46ab2df743db99e79b6c5b 292 Pfam PF13612 Transposase DDE domain 112 267 1.3E-25 T 06-07-2017 IPR025668 Transposase DDE domain GTHT12_RS11775 911076826d596b105c2c0c10084d368c 372 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 4 358 2.1E-61 T 06-07-2017 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 GTHT12_RS11775 911076826d596b105c2c0c10084d368c 372 Pfam PF03845 Spore germination protein 5 315 1.7E-44 T 06-07-2017 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 GTHT12_RS01265 5bfc9d9b0cebf25324ea27ef2555ea8c 242 SUPERFAMILY SSF88713 31 231 9.64E-54 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 GTHT12_RS01265 5bfc9d9b0cebf25324ea27ef2555ea8c 242 Pfam PF01522 Polysaccharide deacetylase 36 145 1.4E-28 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 GTHT12_RS01265 5bfc9d9b0cebf25324ea27ef2555ea8c 242 Gene3D G3DSA:3.20.20.370 4 234 1.0E-53 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 GTHT12_RS10010 bd5dc51936bec30239803a50d495c2ee 358 SUPERFAMILY SSF53822 34 345 3.06E-74 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS10010 bd5dc51936bec30239803a50d495c2ee 358 Pfam PF13407 Periplasmic binding protein domain 34 311 2.1E-67 T 06-07-2017 IPR025997 Periplasmic binding protein GTHT12_RS10010 bd5dc51936bec30239803a50d495c2ee 358 Gene3D G3DSA:3.40.50.2300 147 345 2.1E-38 T 06-07-2017 GTHT12_RS10010 bd5dc51936bec30239803a50d495c2ee 358 Gene3D G3DSA:3.40.50.2300 31 146 2.3E-32 T 06-07-2017 GTHT12_RS12265 00a50dde9035874a325570ed8d727175 114 Gene3D G3DSA:2.60.300.12 3 108 3.9E-9 T 06-07-2017 IPR000361 FeS cluster biogenesis GTHT12_RS12265 00a50dde9035874a325570ed8d727175 114 Pfam PF01521 Iron-sulphur cluster biosynthesis 4 107 5.0E-24 T 06-07-2017 IPR000361 FeS cluster biogenesis GTHT12_RS12265 00a50dde9035874a325570ed8d727175 114 SUPERFAMILY SSF89360 4 107 4.19E-27 T 06-07-2017 IPR000361 FeS cluster biogenesis GTHT12_RS00540 05f113852b0b90fa168650d96d567808 160 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 2 157 37.346 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 GTHT12_RS00540 05f113852b0b90fa168650d96d567808 160 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 36 51 - T 06-07-2017 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 GTHT12_RS00540 05f113852b0b90fa168650d96d567808 160 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3 157 4.7E-72 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 GTHT12_RS00540 05f113852b0b90fa168650d96d567808 160 Pfam PF02542 YgbB family 2 156 2.2E-68 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 GTHT12_RS00540 05f113852b0b90fa168650d96d567808 160 Gene3D G3DSA:3.30.1330.50 1 157 1.5E-75 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 GTHT12_RS00540 05f113852b0b90fa168650d96d567808 160 SUPERFAMILY SSF69765 1 157 1.44E-68 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 GTHT12_RS06905 6978bbe665b3c72c3739433e6e2a47b0 70 ProDom PD048972 UPF0154 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED FAMILY YNEF SUPERFAMILY MG335.1 EXPORTED MYCGA5700 2 40 3.0E-14 T 06-07-2017 IPR005359 Protein with unknown function UPF0154 GTHT12_RS06905 6978bbe665b3c72c3739433e6e2a47b0 70 Pfam PF03672 Uncharacterised protein family (UPF0154) 9 67 8.4E-29 T 06-07-2017 IPR005359 Protein with unknown function UPF0154 GTHT12_RS17530 15a88c9249d79bc61fe98f396a9af436 192 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 13 184 6.0E-70 T 06-07-2017 IPR006340 Protein of unknown function DUF436 GTHT12_RS17530 15a88c9249d79bc61fe98f396a9af436 192 PIRSF PIRSF007510 4 184 1.4E-76 T 06-07-2017 IPR006340 Protein of unknown function DUF436 GTHT12_RS17530 15a88c9249d79bc61fe98f396a9af436 192 Gene3D G3DSA:3.40.50.10360 6 189 1.8E-82 T 06-07-2017 IPR006340 Protein of unknown function DUF436 GTHT12_RS17530 15a88c9249d79bc61fe98f396a9af436 192 SUPERFAMILY SSF110710 6 188 6.54E-78 T 06-07-2017 GTHT12_RS17530 15a88c9249d79bc61fe98f396a9af436 192 Pfam PF04260 Protein of unknown function (DUF436) 11 181 7.6E-76 T 06-07-2017 IPR006340 Protein of unknown function DUF436 GTHT12_RS17530 15a88c9249d79bc61fe98f396a9af436 192 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 11 181 4.7E-72 T 06-07-2017 IPR006340 Protein of unknown function DUF436 GTHT12_RS17530 15a88c9249d79bc61fe98f396a9af436 192 Hamap MF_00800 UPF0340 protein . 1 192 97.908 T 06-07-2017 IPR006340 Protein of unknown function DUF436 GTHT12_RS12825 b99d638cd3061daf1ad94ba0ef586df9 70 SUPERFAMILY SSF158379 1 62 1.57E-23 T 06-07-2017 IPR023164 YqgQ-like domain GTHT12_RS12825 b99d638cd3061daf1ad94ba0ef586df9 70 Pfam PF06014 Bacterial protein of unknown function (DUF910) 1 60 3.2E-29 T 06-07-2017 IPR009256 Protein of unknown function DUF910 GTHT12_RS12825 b99d638cd3061daf1ad94ba0ef586df9 70 Gene3D G3DSA:1.10.287.760 1 67 3.3E-30 T 06-07-2017 IPR023164 YqgQ-like domain GTHT12_RS02805 144499f8562125c935f9f917d811ea25 485 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 7 454 1.3E-119 T 06-07-2017 IPR003846 Uncharacterised protein family UPF0061 GTHT12_RS02805 144499f8562125c935f9f917d811ea25 485 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 4 471 45.577 T 06-07-2017 IPR003846 Uncharacterised protein family UPF0061 GTHT12_RS08665 672c30b70d0b30312f5dcb5d06450b53 275 Gene3D G3DSA:1.10.510.10 137 247 5.3E-14 T 06-07-2017 GTHT12_RS08665 672c30b70d0b30312f5dcb5d06450b53 275 Gene3D G3DSA:3.30.200.20 17 136 7.0E-31 T 06-07-2017 GTHT12_RS08665 672c30b70d0b30312f5dcb5d06450b53 275 SMART SM00219 29 243 6.9E-5 T 06-07-2017 IPR020635 Tyrosine-protein kinase, catalytic domain GO:0004713|GO:0006468 GTHT12_RS08665 672c30b70d0b30312f5dcb5d06450b53 275 SUPERFAMILY SSF56112 13 247 2.29E-47 T 06-07-2017 IPR011009 Protein kinase-like domain GTHT12_RS08665 672c30b70d0b30312f5dcb5d06450b53 275 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 35 58 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 GTHT12_RS08665 672c30b70d0b30312f5dcb5d06450b53 275 Pfam PF00069 Protein kinase domain 29 180 1.8E-29 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 GTHT12_RS17720 c9bf6092f148809f2e38499c51e50fac 222 Pfam PF02163 Peptidase family M50 118 182 1.7E-8 T 06-07-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 GTHT12_RS11235 bf019c9a301a6e1584867e2c33ce6f03 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 5.6E-64 T 06-07-2017 GTHT12_RS11235 bf019c9a301a6e1584867e2c33ce6f03 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 1.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS11235 bf019c9a301a6e1584867e2c33ce6f03 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS11235 bf019c9a301a6e1584867e2c33ce6f03 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 1.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS11235 bf019c9a301a6e1584867e2c33ce6f03 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS11235 bf019c9a301a6e1584867e2c33ce6f03 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS11235 bf019c9a301a6e1584867e2c33ce6f03 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 1.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS11235 bf019c9a301a6e1584867e2c33ce6f03 256 SUPERFAMILY SSF51735 6 255 7.43E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS11235 bf019c9a301a6e1584867e2c33ce6f03 256 Gene3D G3DSA:3.40.50.720 1 255 5.8E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS11235 bf019c9a301a6e1584867e2c33ce6f03 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.2E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS11235 bf019c9a301a6e1584867e2c33ce6f03 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.2E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS11235 bf019c9a301a6e1584867e2c33ce6f03 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 1.2E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS17510 60b1211895e506fbb599d9cf7c596dae 122 ProDom PD020811 ATP SYNTHASE I ION HYDROLASE SUBUNIT I CF0 MEMBRANE HYDROGEN 22 117 2.0E-13 T 06-07-2017 GTHT12_RS17510 60b1211895e506fbb599d9cf7c596dae 122 Pfam PF03899 ATP synthase I chain 12 103 4.4E-15 T 06-07-2017 IPR005598 ATP synthase protein I GTHT12_RS02910 58477a03a55793c4207a2149c9e2d8be 269 Gene3D G3DSA:1.10.10.10 112 156 2.6E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS02910 58477a03a55793c4207a2149c9e2d8be 269 Gene3D G3DSA:1.10.10.10 65 110 1.2E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS02910 58477a03a55793c4207a2149c9e2d8be 269 Hamap MF_01114 Regulatory protein RecX [recX]. 46 213 16.515 T 06-07-2017 IPR003783 Regulatory protein RecX GO:0006282 GTHT12_RS02910 58477a03a55793c4207a2149c9e2d8be 269 Pfam PF02631 RecX family 88 208 2.6E-29 T 06-07-2017 IPR003783 Regulatory protein RecX GO:0006282 GTHT12_RS02910 58477a03a55793c4207a2149c9e2d8be 269 Pfam PF02631 RecX family 214 266 3.4E-4 T 06-07-2017 IPR003783 Regulatory protein RecX GO:0006282 GTHT12_RS02260 f4df8c84060eae322e40da42025bee1d 417 Gene3D G3DSA:1.10.287.950 166 372 1.4E-58 T 06-07-2017 GTHT12_RS02260 f4df8c84060eae322e40da42025bee1d 417 Gene3D G3DSA:1.10.287.950 99 165 3.5E-5 T 06-07-2017 GTHT12_RS02260 f4df8c84060eae322e40da42025bee1d 417 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 169 198 1.1E-5 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 GTHT12_RS02260 f4df8c84060eae322e40da42025bee1d 417 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 268 297 1.1E-5 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 GTHT12_RS02260 f4df8c84060eae322e40da42025bee1d 417 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 185 415 2.0E-52 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 GTHT12_RS02260 f4df8c84060eae322e40da42025bee1d 417 SMART SM00304 305 361 72.0 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS02260 f4df8c84060eae322e40da42025bee1d 417 SMART SM00304 60 112 1.7E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS02260 f4df8c84060eae322e40da42025bee1d 417 SUPERFAMILY SSF58104 80 114 2.49E-72 T 06-07-2017 GTHT12_RS02260 f4df8c84060eae322e40da42025bee1d 417 SUPERFAMILY SSF58104 147 415 2.49E-72 T 06-07-2017 GTHT12_RS02260 f4df8c84060eae322e40da42025bee1d 417 SMART SM00283 141 416 4.5E-83 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 GTHT12_RS02260 f4df8c84060eae322e40da42025bee1d 417 Pfam PF00672 HAMP domain 38 106 1.1E-7 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 GTHT12_RS02190 4fa174a43fe2435f3b58bd04560a8001 234 Gene3D G3DSA:3.40.50.2300 3 121 5.6E-35 T 06-07-2017 GTHT12_RS02190 4fa174a43fe2435f3b58bd04560a8001 234 SMART SM00448 2 112 2.3E-38 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS02190 4fa174a43fe2435f3b58bd04560a8001 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 223 3.5E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS02190 4fa174a43fe2435f3b58bd04560a8001 234 SUPERFAMILY SSF52172 2 124 4.7E-37 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS02190 4fa174a43fe2435f3b58bd04560a8001 234 SMART SM00862 147 224 3.4E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 GTHT12_RS02190 4fa174a43fe2435f3b58bd04560a8001 234 Pfam PF00072 Response regulator receiver domain 5 112 2.2E-23 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS02190 4fa174a43fe2435f3b58bd04560a8001 234 SUPERFAMILY SSF46894 129 225 6.52E-24 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GTHT12_RS02190 4fa174a43fe2435f3b58bd04560a8001 234 Gene3D G3DSA:1.10.10.10 127 227 9.5E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS17030 596539965e0ada0a0fb1bdf59d984d5b 280 Gene3D G3DSA:1.10.3720.10 58 233 4.5E-53 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS17030 596539965e0ada0a0fb1bdf59d984d5b 280 SUPERFAMILY SSF161098 52 234 6.8E-53 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS17030 596539965e0ada0a0fb1bdf59d984d5b 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 233 1.2E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS02055 b7686917a63ae8965edf9dfa1b11f0ef 396 Pfam PF01610 Transposase 155 382 5.4E-66 T 06-07-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain GTHT12_RS02055 b7686917a63ae8965edf9dfa1b11f0ef 396 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 34 78 8.5E-14 T 06-07-2017 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger GTHT12_RS02055 b7686917a63ae8965edf9dfa1b11f0ef 396 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 86 132 5.5E-10 T 06-07-2017 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain GTHT12_RS00280 a6ff24aa90d4e1cfa3fe4c437955a561 186 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 06-07-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 GTHT12_RS00280 a6ff24aa90d4e1cfa3fe4c437955a561 186 Gene3D G3DSA:3.40.50.1470 2 185 1.6E-75 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 GTHT12_RS00280 a6ff24aa90d4e1cfa3fe4c437955a561 186 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 06-07-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 GTHT12_RS00280 a6ff24aa90d4e1cfa3fe4c437955a561 186 Pfam PF01195 Peptidyl-tRNA hydrolase 3 183 2.0E-60 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 GTHT12_RS00280 a6ff24aa90d4e1cfa3fe4c437955a561 186 SUPERFAMILY SSF53178 2 185 1.15E-69 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 GTHT12_RS00280 a6ff24aa90d4e1cfa3fe4c437955a561 186 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 178 38.251 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 GTHT12_RS00280 a6ff24aa90d4e1cfa3fe4c437955a561 186 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 2 185 1.1E-70 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 GTHT12_RS04925 be7c60f3b534dc99f2738aa6055c01e6 274 Pfam PF00583 Acetyltransferase (GNAT) family 48 113 9.7E-5 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS04925 be7c60f3b534dc99f2738aa6055c01e6 274 Gene3D G3DSA:3.40.630.30 11 114 6.4E-11 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS04925 be7c60f3b534dc99f2738aa6055c01e6 274 SUPERFAMILY SSF55729 10 187 1.5E-12 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS09505 8c154b63719e3d4499231ac09c55b0ce 292 Gene3D G3DSA:3.20.20.190 15 285 9.4E-81 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 GTHT12_RS09505 8c154b63719e3d4499231ac09c55b0ce 292 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 40 278 4.2E-52 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 GTHT12_RS09505 8c154b63719e3d4499231ac09c55b0ce 292 SUPERFAMILY SSF51695 35 281 1.67E-75 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 GTHT12_RS06690 51cd00f5e5b383080eac681813b525e8 82 PIRSF PIRSF004764 1 82 2.3E-30 T 06-07-2017 IPR024702 Uncharacterised conserved protein YmfJ GTHT12_RS06690 51cd00f5e5b383080eac681813b525e8 82 Pfam PF11588 Protein of unknown function (DUF3243) 3 80 4.4E-37 T 06-07-2017 IPR021637 Protein of unknown function DUF3243 GTHT12_RS06460 aab44e62d74fd1058d7d0b797bfe4f69 165 Pfam PF03975 CheD chemotactic sensory transduction 50 157 6.4E-35 T 06-07-2017 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 GTHT12_RS06460 aab44e62d74fd1058d7d0b797bfe4f69 165 SUPERFAMILY SSF64438 6 163 7.78E-46 T 06-07-2017 IPR011324 Cytotoxic necrotizing factor-like, catalytic GTHT12_RS06460 aab44e62d74fd1058d7d0b797bfe4f69 165 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 3 161 27.541 T 06-07-2017 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 GTHT12_RS11245 42b39158f1e8ceb999963b776879dbea 251 Gene3D G3DSA:1.10.3720.10 48 241 1.4E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS11245 42b39158f1e8ceb999963b776879dbea 251 SUPERFAMILY SSF161098 48 231 7.46E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS11245 42b39158f1e8ceb999963b776879dbea 251 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 237 1.9E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS16790 63f05fe1114c27ab46dcbc780e0dab8c 145 SUPERFAMILY SSF52980 36 143 3.75E-15 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 GTHT12_RS16790 63f05fe1114c27ab46dcbc780e0dab8c 145 Pfam PF04480 Protein of unknown function (DUF559) 48 141 3.6E-12 T 06-07-2017 IPR007569 Domain of unknown function DUF559 GTHT12_RS16790 63f05fe1114c27ab46dcbc780e0dab8c 145 Gene3D G3DSA:3.40.960.10 48 142 1.1E-6 T 06-07-2017 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 GTHT12_RS18655 d23f9a34ed37862a12d8075d29ac1357 70 Pfam PF11148 Protein of unknown function (DUF2922) 2 67 1.1E-20 T 06-07-2017 IPR021321 Protein of unknown function DUF2922 GTHT12_RS10700 26c2ed25cbb27701df50d28209085243 356 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 7 346 5.6E-148 T 06-07-2017 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 GTHT12_RS10700 26c2ed25cbb27701df50d28209085243 356 SUPERFAMILY SSF52518 5 348 4.42E-109 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS10700 26c2ed25cbb27701df50d28209085243 356 Gene3D G3DSA:3.40.50.970 3 345 3.8E-133 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold GTHT12_RS10700 26c2ed25cbb27701df50d28209085243 356 Pfam PF00676 Dehydrogenase E1 component 39 325 2.6E-92 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 GTHT12_RS07470 283303656ad1a033fbf59ed26dd1090d 197 Gene3D G3DSA:3.40.50.300 6 197 1.6E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07470 283303656ad1a033fbf59ed26dd1090d 197 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 22 158 7.2E-10 T 06-07-2017 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 GTHT12_RS07470 283303656ad1a033fbf59ed26dd1090d 197 SUPERFAMILY SSF52540 18 195 5.58E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12890 c82fa4000872d9b366f9d35009e52fe9 289 Gene3D G3DSA:1.10.3720.10 63 287 2.5E-42 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS12890 c82fa4000872d9b366f9d35009e52fe9 289 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 18 286 1.3E-79 T 06-07-2017 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 GTHT12_RS12890 c82fa4000872d9b366f9d35009e52fe9 289 SUPERFAMILY SSF161098 26 273 1.83E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS12890 c82fa4000872d9b366f9d35009e52fe9 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 281 2.1E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS00935 9697bfcd2a58bdce5ea075689f6d8ccc 426 Pfam PF07949 YbbR-like protein 51 131 1.6E-10 T 06-07-2017 IPR012505 YbbR-like GTHT12_RS00935 9697bfcd2a58bdce5ea075689f6d8ccc 426 Pfam PF07949 YbbR-like protein 141 224 3.5E-17 T 06-07-2017 IPR012505 YbbR-like GTHT12_RS00935 9697bfcd2a58bdce5ea075689f6d8ccc 426 Pfam PF07949 YbbR-like protein 233 312 4.7E-19 T 06-07-2017 IPR012505 YbbR-like GTHT12_RS02005 49b6629055f15360a8065586bc946501 141 Pfam PF13349 Putative adhesin 46 140 5.3E-9 T 06-07-2017 IPR025164 Putative adhesin GTHT12_RS16615 b2a84327b0d8539afa3d6ca2912c9413 113 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 4 109 6.8E-22 T 06-07-2017 IPR003791 Protein of unknown function UPF0178 GTHT12_RS16095 fd3db9aa0aa5f458d520e7898a8a410f 228 Pfam PF00005 ABC transporter 18 165 1.2E-37 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS16095 fd3db9aa0aa5f458d520e7898a8a410f 228 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 213 9.2E-90 T 06-07-2017 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 GTHT12_RS16095 fd3db9aa0aa5f458d520e7898a8a410f 228 SMART SM00382 27 214 1.5E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS16095 fd3db9aa0aa5f458d520e7898a8a410f 228 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS16095 fd3db9aa0aa5f458d520e7898a8a410f 228 Gene3D G3DSA:3.40.50.300 1 219 2.2E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16095 fd3db9aa0aa5f458d520e7898a8a410f 228 SUPERFAMILY SSF52540 1 222 8.73E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS15825 1185f37ec3c93d12b5a05a975477e4f6 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.0E-11 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GTHT12_RS15825 1185f37ec3c93d12b5a05a975477e4f6 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.0E-11 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GTHT12_RS15825 1185f37ec3c93d12b5a05a975477e4f6 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.0E-11 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GTHT12_RS15825 1185f37ec3c93d12b5a05a975477e4f6 305 Pfam PF03466 LysR substrate binding domain 89 292 4.8E-40 T 06-07-2017 IPR005119 LysR, substrate-binding GTHT12_RS15825 1185f37ec3c93d12b5a05a975477e4f6 305 SUPERFAMILY SSF53850 89 294 1.4E-37 T 06-07-2017 GTHT12_RS15825 1185f37ec3c93d12b5a05a975477e4f6 305 Gene3D G3DSA:3.40.190.10 89 175 2.4E-19 T 06-07-2017 GTHT12_RS15825 1185f37ec3c93d12b5a05a975477e4f6 305 Gene3D G3DSA:3.40.190.10 176 261 1.5E-20 T 06-07-2017 GTHT12_RS15825 1185f37ec3c93d12b5a05a975477e4f6 305 Gene3D G3DSA:1.10.10.10 1 87 1.1E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS15825 1185f37ec3c93d12b5a05a975477e4f6 305 SUPERFAMILY SSF46785 3 87 9.58E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS15825 1185f37ec3c93d12b5a05a975477e4f6 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.1E-22 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 GTHT12_RS06135 f5a323e5a7a550abc58121941f7e4bec 26 Pfam PF08183 Stage V sporulation protein family 1 25 5.4E-18 T 06-07-2017 IPR012609 Sporulation stage V, protein M GTHT12_RS16765 a413ca8a53a64b7139ebd39bf114047b 731 Pfam PF02810 SEC-C motif 5 22 4.1E-10 T 06-07-2017 IPR004027 SEC-C motif GTHT12_RS16765 a413ca8a53a64b7139ebd39bf114047b 731 Gene3D G3DSA:3.10.450.50 2 23 1.7E-8 T 06-07-2017 IPR032710 NTF2-like domain GTHT12_RS16765 a413ca8a53a64b7139ebd39bf114047b 731 SUPERFAMILY SSF103642 3 24 8.01E-8 T 06-07-2017 GTHT12_RS16405 a142e2fd9830c722e11af53a8c628319 381 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 29 365 6.4E-122 T 06-07-2017 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 GTHT12_RS16405 a142e2fd9830c722e11af53a8c628319 381 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 6 368 9.4E-166 T 06-07-2017 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 GTHT12_RS16405 a142e2fd9830c722e11af53a8c628319 381 Gene3D G3DSA:3.40.50.2000 3 206 1.1E-87 T 06-07-2017 GTHT12_RS16405 a142e2fd9830c722e11af53a8c628319 381 Gene3D G3DSA:3.40.50.2000 207 368 3.8E-66 T 06-07-2017 GTHT12_RS16405 a142e2fd9830c722e11af53a8c628319 381 SUPERFAMILY SSF53756 4 374 5.5E-142 T 06-07-2017 GTHT12_RS02375 bb3468b03630c2af645f86435a75bf15 241 SMART SM00345 15 74 4.0E-22 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS02375 bb3468b03630c2af645f86435a75bf15 241 SUPERFAMILY SSF48008 95 234 3.14E-32 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal GTHT12_RS02375 bb3468b03630c2af645f86435a75bf15 241 Gene3D G3DSA:1.20.120.530 93 237 5.7E-35 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal GTHT12_RS02375 bb3468b03630c2af645f86435a75bf15 241 SMART SM00895 99 226 5.3E-26 T 06-07-2017 IPR011711 GntR, C-terminal GTHT12_RS02375 bb3468b03630c2af645f86435a75bf15 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.9E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS02375 bb3468b03630c2af645f86435a75bf15 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.9E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS02375 bb3468b03630c2af645f86435a75bf15 241 Pfam PF07729 FCD domain 100 225 9.9E-28 T 06-07-2017 IPR011711 GntR, C-terminal GTHT12_RS02375 bb3468b03630c2af645f86435a75bf15 241 SUPERFAMILY SSF46785 2 86 3.58E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS02375 bb3468b03630c2af645f86435a75bf15 241 Gene3D G3DSA:1.10.10.10 4 78 1.2E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS02375 bb3468b03630c2af645f86435a75bf15 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.9E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 GTHT12_RS01965 6e20de1d40c79f58e2811e47ec67d4a7 118 SUPERFAMILY SSF159121 28 113 5.1E-25 T 06-07-2017 GTHT12_RS01965 6e20de1d40c79f58e2811e47ec67d4a7 118 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 1 111 2.6E-21 T 06-07-2017 IPR006542 Protein of unknown function DUF1093 GTHT12_RS01965 6e20de1d40c79f58e2811e47ec67d4a7 118 Pfam PF06486 Protein of unknown function (DUF1093) 33 100 4.9E-19 T 06-07-2017 IPR006542 Protein of unknown function DUF1093 GTHT12_RS00390 974a8a0bf60bd8a12386c2132b5f1709 296 SUPERFAMILY SSF64397 5 243 4.32E-79 T 06-07-2017 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 GTHT12_RS00390 974a8a0bf60bd8a12386c2132b5f1709 296 SUPERFAMILY SSF118352 233 290 4.32E-21 T 06-07-2017 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 GTHT12_RS00390 974a8a0bf60bd8a12386c2132b5f1709 296 PIRSF PIRSF005261 1 294 4.1E-79 T 06-07-2017 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 GTHT12_RS00390 974a8a0bf60bd8a12386c2132b5f1709 296 Pfam PF01430 Hsp33 protein 5 281 3.2E-93 T 06-07-2017 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 GTHT12_RS00390 974a8a0bf60bd8a12386c2132b5f1709 296 Hamap MF_00117 33 kDa chaperonin [hslO]. 4 293 42.37 T 06-07-2017 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 GTHT12_RS00390 974a8a0bf60bd8a12386c2132b5f1709 296 Gene3D G3DSA:3.55.30.10 5 235 2.9E-86 T 06-07-2017 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 GTHT12_RS00390 974a8a0bf60bd8a12386c2132b5f1709 296 Gene3D G3DSA:3.90.1280.10 236 290 1.5E-25 T 06-07-2017 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 GTHT12_RS02945 c7bdf66d1b3c0f85e8904d49f0f1d636 115 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 4 111 2.0E-36 T 06-07-2017 IPR018745 Domain of unknown function DUF2294 GTHT12_RS17220 10c84606e0647931a3b2c4aad61a0fe2 363 Gene3D G3DSA:3.40.50.2000 255 359 5.1E-7 T 06-07-2017 GTHT12_RS17220 10c84606e0647931a3b2c4aad61a0fe2 363 SUPERFAMILY SSF53756 11 292 5.39E-7 T 06-07-2017 GTHT12_RS15365 29541b0075866d095dd65fd6157b21ad 798 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 57 110 1.9E-10 T 06-07-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS15365 29541b0075866d095dd65fd6157b21ad 798 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 214 235 7.7E-42 T 06-07-2017 GTHT12_RS15365 29541b0075866d095dd65fd6157b21ad 798 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 71 96 7.7E-42 T 06-07-2017 GTHT12_RS15365 29541b0075866d095dd65fd6157b21ad 798 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 431 450 7.7E-42 T 06-07-2017 GTHT12_RS15365 29541b0075866d095dd65fd6157b21ad 798 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 147 168 7.7E-42 T 06-07-2017 GTHT12_RS15365 29541b0075866d095dd65fd6157b21ad 798 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 304 316 7.7E-42 T 06-07-2017 GTHT12_RS15365 29541b0075866d095dd65fd6157b21ad 798 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 236 262 7.7E-42 T 06-07-2017 GTHT12_RS15365 29541b0075866d095dd65fd6157b21ad 798 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 100 120 7.7E-42 T 06-07-2017 GTHT12_RS15365 29541b0075866d095dd65fd6157b21ad 798 Pfam PF13244 Domain of unknown function (DUF4040) 633 696 1.2E-19 T 06-07-2017 IPR025383 Domain of unknown function DUF4040 GTHT12_RS15365 29541b0075866d095dd65fd6157b21ad 798 TIGRFAM TIGR00940 2a6301s01: monovalent cation:proton antiporter 2 793 0.0 T 06-07-2017 IPR005663 Monovalent cation proton antiporter subunit A GO:0015077|GO:0030004 GTHT12_RS15365 29541b0075866d095dd65fd6157b21ad 798 Pfam PF00361 Proton-conducting membrane transporter 123 415 2.9E-64 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS15365 29541b0075866d095dd65fd6157b21ad 798 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 73 93 5.2E-6 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 GTHT12_RS15365 29541b0075866d095dd65fd6157b21ad 798 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 362 384 5.2E-6 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 GTHT12_RS15365 29541b0075866d095dd65fd6157b21ad 798 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 254 276 5.2E-6 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 GTHT12_RS13735 614702c592d2a51b60ba7fc726d5faf4 455 Pfam PF04294 VanW like protein 227 294 2.9E-7 T 06-07-2017 IPR007391 Vancomycin resistance VanW GTHT12_RS13735 614702c592d2a51b60ba7fc726d5faf4 455 Pfam PF07501 G5 domain 311 375 4.9E-5 T 06-07-2017 IPR011098 G5 domain GTHT12_RS13735 614702c592d2a51b60ba7fc726d5faf4 455 SMART SM01208 304 377 3.6E-4 T 06-07-2017 IPR011098 G5 domain GTHT12_RS02030 5b7b169fcd0bfeeb15ab4c87882924ee 127 Pfam PF13349 Putative adhesin 3 125 3.0E-18 T 06-07-2017 IPR025164 Putative adhesin GTHT12_RS04960 5283f1142fda2065bea461652afee440 66 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 39 53 - T 06-07-2017 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 GTHT12_RS04960 5283f1142fda2065bea461652afee440 66 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 6 60 1.7E-20 T 06-07-2017 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 GTHT12_RS04960 5283f1142fda2065bea461652afee440 66 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 21 30 - T 06-07-2017 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 GTHT12_RS05025 1dc700ee9685e331ffe798f4c5504ea8 355 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 35 335 2.8E-129 T 06-07-2017 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 GTHT12_RS05025 1dc700ee9685e331ffe798f4c5504ea8 355 Gene3D G3DSA:1.20.120.420 8 156 1.8E-51 T 06-07-2017 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 GTHT12_RS05025 1dc700ee9685e331ffe798f4c5504ea8 355 SUPERFAMILY SSF100950 7 339 1.51E-119 T 06-07-2017 GTHT12_RS05025 1dc700ee9685e331ffe798f4c5504ea8 355 Pfam PF01008 Initiation factor 2 subunit family 48 334 9.9E-91 T 06-07-2017 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 GTHT12_RS05025 1dc700ee9685e331ffe798f4c5504ea8 355 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 6 346 39.372 T 06-07-2017 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 GTHT12_RS05025 1dc700ee9685e331ffe798f4c5504ea8 355 Gene3D G3DSA:3.40.50.10470 157 341 6.2E-71 T 06-07-2017 GTHT12_RS05025 1dc700ee9685e331ffe798f4c5504ea8 355 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 8 334 6.3E-139 T 06-07-2017 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 GTHT12_RS03110 b5fb5d5b8f16ed470d56761865f67df2 428 Gene3D G3DSA:3.90.1150.10 322 427 2.4E-43 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS03110 b5fb5d5b8f16ed470d56761865f67df2 428 Gene3D G3DSA:3.90.1150.10 3 72 2.4E-43 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS03110 b5fb5d5b8f16ed470d56761865f67df2 428 SUPERFAMILY SSF53383 2 428 2.11E-127 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS03110 b5fb5d5b8f16ed470d56761865f67df2 428 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 428 95.838 T 06-07-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 GTHT12_RS03110 b5fb5d5b8f16ed470d56761865f67df2 428 Pfam PF00202 Aminotransferase class-III 36 421 5.0E-70 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GTHT12_RS03110 b5fb5d5b8f16ed470d56761865f67df2 428 Gene3D G3DSA:3.40.640.10 73 319 2.5E-80 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS03110 b5fb5d5b8f16ed470d56761865f67df2 428 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 5 427 1.1E-172 T 06-07-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 GTHT12_RS03110 b5fb5d5b8f16ed470d56761865f67df2 428 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 273 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 GTHT12_RS18550 da269605a4a096d69f24baaac05a4ad2 282 SUPERFAMILY SSF56281 28 276 3.41E-55 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS18550 da269605a4a096d69f24baaac05a4ad2 282 Gene3D G3DSA:3.60.15.10 24 279 2.7E-42 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS18550 da269605a4a096d69f24baaac05a4ad2 282 SMART SM00849 40 234 1.6E-11 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS18550 da269605a4a096d69f24baaac05a4ad2 282 Pfam PF00753 Metallo-beta-lactamase superfamily 38 233 6.6E-20 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS14765 442650f2294a74ec5667ce9d78293d4c 190 Gene3D G3DSA:3.40.50.150 17 162 6.9E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS14765 442650f2294a74ec5667ce9d78293d4c 190 Pfam PF06962 Putative rRNA methylase 48 187 1.3E-50 T 06-07-2017 IPR010719 Putative rRNA methylase GTHT12_RS14765 442650f2294a74ec5667ce9d78293d4c 190 SUPERFAMILY SSF53335 7 184 7.76E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS10485 892484a12336e41584969dda41b26a0b 488 Gene3D G3DSA:3.40.309.10 269 458 7.8E-71 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 GTHT12_RS10485 892484a12336e41584969dda41b26a0b 488 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10485 892484a12336e41584969dda41b26a0b 488 SUPERFAMILY SSF53720 5 487 1.44E-165 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10485 892484a12336e41584969dda41b26a0b 488 Gene3D G3DSA:3.40.605.10 9 268 7.1E-97 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10485 892484a12336e41584969dda41b26a0b 488 Pfam PF00171 Aldehyde dehydrogenase family 18 484 1.0E-171 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS10485 892484a12336e41584969dda41b26a0b 488 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 282 293 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 GTHT12_RS16495 6992f13bb756f29eebf7670a93b485e3 431 Pfam PF01547 Bacterial extracellular solute-binding protein 54 347 1.8E-40 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 GTHT12_RS16495 6992f13bb756f29eebf7670a93b485e3 431 Gene3D G3DSA:3.40.190.10 164 363 3.2E-40 T 06-07-2017 GTHT12_RS16495 6992f13bb756f29eebf7670a93b485e3 431 SUPERFAMILY SSF53850 20 428 2.94E-81 T 06-07-2017 GTHT12_RS18015 6525715bb7a142de5a9da0e504f1d373 304 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 3 84 2.7E-13 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 GTHT12_RS18015 6525715bb7a142de5a9da0e504f1d373 304 Gene3D G3DSA:1.10.150.130 3 94 8.6E-18 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal GTHT12_RS18015 6525715bb7a142de5a9da0e504f1d373 304 SUPERFAMILY SSF56349 3 298 2.21E-49 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 GTHT12_RS18015 6525715bb7a142de5a9da0e504f1d373 304 Pfam PF00589 Phage integrase family 110 290 2.6E-30 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS18015 6525715bb7a142de5a9da0e504f1d373 304 Gene3D G3DSA:1.10.443.10 110 298 6.1E-40 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS07980 947f9de6b18094e4e2addcb3fece1d0f 435 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 332 352 - T 06-07-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 GTHT12_RS07980 947f9de6b18094e4e2addcb3fece1d0f 435 Pfam PF00860 Permease family 10 385 2.0E-120 T 06-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 GTHT12_RS07980 947f9de6b18094e4e2addcb3fece1d0f 435 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 7 415 1.6E-142 T 06-07-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 GTHT12_RS07980 947f9de6b18094e4e2addcb3fece1d0f 435 TIGRFAM TIGR03173 pbuX: xanthine permease 11 417 2.3E-166 T 06-07-2017 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 GTHT12_RS06860 b04104c977aade45559a560e9be32014 423 Pfam PF06838 Methionine gamma-lyase 14 415 1.1E-207 T 06-07-2017 IPR009651 Putative methionine gamma-lyase GTHT12_RS06860 b04104c977aade45559a560e9be32014 423 SUPERFAMILY SSF53383 59 399 5.47E-46 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS06860 b04104c977aade45559a560e9be32014 423 Gene3D G3DSA:3.40.640.10 57 272 3.4E-38 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS02270 1f775c44fe43b9dd7d4e57f5a00d5663 391 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 GTHT12_RS02270 1f775c44fe43b9dd7d4e57f5a00d5663 391 SUPERFAMILY SSF53383 1 384 2.45E-102 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS02270 1f775c44fe43b9dd7d4e57f5a00d5663 391 Gene3D G3DSA:3.40.640.10 45 258 1.2E-57 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS02270 1f775c44fe43b9dd7d4e57f5a00d5663 391 Pfam PF00155 Aminotransferase class I and II 32 379 5.7E-61 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 GTHT12_RS02270 1f775c44fe43b9dd7d4e57f5a00d5663 391 Gene3D G3DSA:3.90.1150.10 259 382 3.4E-39 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS10375 69ece8cd49c47583a12ed2c88adc5af8 151 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 8 144 1.5E-22 T 06-07-2017 IPR009936 Protein of unknown function DUF1468 GTHT12_RS03995 ba04d27d4fe2847738c6c95e73913dcf 68 Gene3D G3DSA:1.20.120.20 6 65 2.1E-4 T 06-07-2017 GTHT12_RS13415 7d43773f465c421149b94b5087c65726 371 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 9 357 1.5E-141 T 06-07-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 GTHT12_RS13415 7d43773f465c421149b94b5087c65726 371 Gene3D G3DSA:3.40.50.620 3 212 2.9E-102 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS13415 7d43773f465c421149b94b5087c65726 371 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 8 358 41.31 T 06-07-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 GTHT12_RS13415 7d43773f465c421149b94b5087c65726 371 Gene3D G3DSA:2.40.30.10 279 367 2.1E-33 T 06-07-2017 GTHT12_RS13415 7d43773f465c421149b94b5087c65726 371 SUPERFAMILY SSF52402 8 244 3.75E-59 T 06-07-2017 GTHT12_RS13415 7d43773f465c421149b94b5087c65726 371 Pfam PF03054 tRNA methyl transferase 9 357 1.9E-147 T 06-07-2017 GTHT12_RS13415 7d43773f465c421149b94b5087c65726 371 Gene3D G3DSA:2.30.30.280 214 277 1.9E-29 T 06-07-2017 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 GTHT12_RS10210 d9e030d499fc6e6e7fdaabf3f9ab0c03 314 Gene3D G3DSA:1.10.3720.10 20 303 9.1E-65 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS10210 d9e030d499fc6e6e7fdaabf3f9ab0c03 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 301 1.0E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS10210 d9e030d499fc6e6e7fdaabf3f9ab0c03 314 SUPERFAMILY SSF161098 71 301 4.32E-62 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS16025 db87574001e9bc84d734a3a385b9b74b 269 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 7 261 17.772 T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 GTHT12_RS16025 db87574001e9bc84d734a3a385b9b74b 269 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 136 148 - T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 GTHT12_RS16025 db87574001e9bc84d734a3a385b9b74b 269 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 11 255 8.6E-80 T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 GTHT12_RS16025 db87574001e9bc84d734a3a385b9b74b 269 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 7 255 7.9E-83 T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 GTHT12_RS09265 8cedd1969a17ae97804a1478d2f7e842 403 Gene3D G3DSA:3.40.50.1100 147 388 1.0E-57 T 06-07-2017 GTHT12_RS09265 8cedd1969a17ae97804a1478d2f7e842 403 SUPERFAMILY SSF53686 4 388 4.85E-90 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GTHT12_RS09265 8cedd1969a17ae97804a1478d2f7e842 403 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 74 379 5.7E-65 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme GTHT12_RS02465 7c89a6bf535c6f14704d0f98cba53e43 357 Pfam PF01384 Phosphate transporter family 17 145 1.1E-17 T 06-07-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 GTHT12_RS02465 7c89a6bf535c6f14704d0f98cba53e43 357 Pfam PF01384 Phosphate transporter family 163 308 7.7E-28 T 06-07-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 GTHT12_RS10800 cbbbb4bb9f05355d485cf52be7db23fd 559 SUPERFAMILY SSF52016 378 558 7.3E-65 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel GTHT12_RS10800 cbbbb4bb9f05355d485cf52be7db23fd 559 SUPERFAMILY SSF143975 4 377 3.53E-142 T 06-07-2017 GTHT12_RS10800 cbbbb4bb9f05355d485cf52be7db23fd 559 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 558 48.216 T 06-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 GTHT12_RS10800 cbbbb4bb9f05355d485cf52be7db23fd 559 Pfam PF00920 Dehydratase family 34 554 4.0E-231 T 06-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 GTHT12_RS10800 cbbbb4bb9f05355d485cf52be7db23fd 559 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 17 558 3.7E-261 T 06-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 GTHT12_RS10800 cbbbb4bb9f05355d485cf52be7db23fd 559 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 GTHT12_RS10800 cbbbb4bb9f05355d485cf52be7db23fd 559 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 466 477 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 GTHT12_RS00095 bc097539e53e64412b3a7937e1ae75d3 428 Gene3D G3DSA:3.10.350.10 51 97 1.5E-14 T 06-07-2017 IPR018392 LysM domain GTHT12_RS00095 bc097539e53e64412b3a7937e1ae75d3 428 SMART SM00257 3 47 4.8E-16 T 06-07-2017 IPR018392 LysM domain GTHT12_RS00095 bc097539e53e64412b3a7937e1ae75d3 428 SMART SM00257 52 96 1.4E-10 T 06-07-2017 IPR018392 LysM domain GTHT12_RS00095 bc097539e53e64412b3a7937e1ae75d3 428 SUPERFAMILY SSF54106 52 96 5.75E-11 T 06-07-2017 IPR018392 LysM domain GTHT12_RS00095 bc097539e53e64412b3a7937e1ae75d3 428 Gene3D G3DSA:3.10.350.10 2 47 2.1E-16 T 06-07-2017 IPR018392 LysM domain GTHT12_RS00095 bc097539e53e64412b3a7937e1ae75d3 428 Gene3D G3DSA:3.20.20.80 172 420 1.5E-37 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 GTHT12_RS00095 bc097539e53e64412b3a7937e1ae75d3 428 SUPERFAMILY SSF51445 128 323 2.51E-48 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS00095 bc097539e53e64412b3a7937e1ae75d3 428 SUPERFAMILY SSF51445 383 425 2.51E-48 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily GTHT12_RS00095 bc097539e53e64412b3a7937e1ae75d3 428 Pfam PF01476 LysM domain 53 96 4.5E-13 T 06-07-2017 IPR018392 LysM domain GTHT12_RS00095 bc097539e53e64412b3a7937e1ae75d3 428 Pfam PF01476 LysM domain 4 47 7.8E-13 T 06-07-2017 IPR018392 LysM domain GTHT12_RS00095 bc097539e53e64412b3a7937e1ae75d3 428 SUPERFAMILY SSF54106 2 47 4.45E-11 T 06-07-2017 IPR018392 LysM domain GTHT12_RS00095 bc097539e53e64412b3a7937e1ae75d3 428 SMART SM00636 103 411 4.7E-34 T 06-07-2017 IPR011583 Chitinase II GO:0004568|GO:0006032 GTHT12_RS00095 bc097539e53e64412b3a7937e1ae75d3 428 Pfam PF00704 Glycosyl hydrolases family 18 185 411 3.0E-25 T 06-07-2017 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0004553|GO:0005975 GTHT12_RS06110 7304312f807518c5a3f0ab6fdeced005 249 Gene3D G3DSA:3.60.40.10 1 242 1.1E-75 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 GTHT12_RS06110 7304312f807518c5a3f0ab6fdeced005 249 SUPERFAMILY SSF81606 2 242 6.41E-69 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 GTHT12_RS06110 7304312f807518c5a3f0ab6fdeced005 249 SMART SM00331 7 242 2.5E-56 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 GTHT12_RS06110 7304312f807518c5a3f0ab6fdeced005 249 Pfam PF13672 Protein phosphatase 2C 15 209 1.1E-18 T 06-07-2017 GTHT12_RS06110 7304312f807518c5a3f0ab6fdeced005 249 SMART SM00332 1 240 3.6E-24 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 GTHT12_RS02155 162bdc6e33b17bfe9f46efe2e07aae21 286 Pfam PF13151 Protein of unknown function (DUF3990) 9 151 2.4E-19 T 06-07-2017 IPR025051 Protein of unknown function DUF3990 GTHT12_RS02155 162bdc6e33b17bfe9f46efe2e07aae21 286 SUPERFAMILY SSF56399 11 58 3.88E-5 T 06-07-2017 GTHT12_RS00430 fd0dc903939c032cffe6aa1765e003ac 73 SUPERFAMILY SSF47413 4 66 6.17E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS00430 fd0dc903939c032cffe6aa1765e003ac 73 Pfam PF01381 Helix-turn-helix 10 64 1.3E-16 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GTHT12_RS00430 fd0dc903939c032cffe6aa1765e003ac 73 SMART SM00530 9 64 5.2E-17 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GTHT12_RS00430 fd0dc903939c032cffe6aa1765e003ac 73 Gene3D G3DSA:1.10.260.40 4 68 8.3E-21 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS17130 e266ace8e8a0e1d55e763e5aa571f690 48 Pfam PF13910 Domain of unknown function (DUF4209) 2 32 1.8E-5 T 06-07-2017 IPR025209 Domain of unknown function DUF4209 GTHT12_RS11215 383e334578496a8e63d733417230e02a 167 Pfam PF07681 DoxX 16 115 2.4E-11 T 06-07-2017 IPR032808 DoxX family GTHT12_RS07705 05a19fb7996d00dcc48cfd087f8aeacb 143 Gene3D G3DSA:3.40.630.30 13 142 2.3E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS07705 05a19fb7996d00dcc48cfd087f8aeacb 143 Pfam PF00583 Acetyltransferase (GNAT) family 59 131 5.2E-8 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS07705 05a19fb7996d00dcc48cfd087f8aeacb 143 SUPERFAMILY SSF55729 9 138 1.23E-19 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS17550 d29571d975a932a11ad2c115d87c0124 183 Pfam PF02659 Putative manganese efflux pump 34 181 2.0E-41 T 06-07-2017 IPR003810 Putative manganese efflux pump GTHT12_RS17550 d29571d975a932a11ad2c115d87c0124 183 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 6 183 21.326 T 06-07-2017 IPR022929 Putative manganese efflux pump MntP GTHT12_RS13935 3b517f0a7c99716dbfae1de2128579e2 74 ProSitePatterns PS00622 LuxR-type HTH domain signature. 26 53 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS13935 3b517f0a7c99716dbfae1de2128579e2 74 Pfam PF00196 Bacterial regulatory proteins, luxR family 12 64 1.3E-23 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS13935 3b517f0a7c99716dbfae1de2128579e2 74 Gene3D G3DSA:1.10.10.10 6 70 6.8E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS13935 3b517f0a7c99716dbfae1de2128579e2 74 SUPERFAMILY SSF46894 8 72 8.16E-23 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 GTHT12_RS13935 3b517f0a7c99716dbfae1de2128579e2 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 42 54 1.5E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS13935 3b517f0a7c99716dbfae1de2128579e2 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 12 26 1.5E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS13935 3b517f0a7c99716dbfae1de2128579e2 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 26 42 1.5E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS13935 3b517f0a7c99716dbfae1de2128579e2 74 SMART SM00421 9 66 1.4E-24 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 GTHT12_RS07760 d67bfe16f55c33f0acdd7250a454ba10 269 Gene3D G3DSA:3.40.1190.20 7 268 5.3E-91 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS07760 d67bfe16f55c33f0acdd7250a454ba10 269 Pfam PF02110 Hydroxyethylthiazole kinase family 11 255 8.4E-94 T 06-07-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GTHT12_RS07760 d67bfe16f55c33f0acdd7250a454ba10 269 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 11 257 2.7E-96 T 06-07-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GTHT12_RS07760 d67bfe16f55c33f0acdd7250a454ba10 269 PIRSF PIRSF000513 5 269 3.2E-97 T 06-07-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GTHT12_RS07760 d67bfe16f55c33f0acdd7250a454ba10 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 19 26 2.2E-43 T 06-07-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GTHT12_RS07760 d67bfe16f55c33f0acdd7250a454ba10 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 32 53 2.2E-43 T 06-07-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GTHT12_RS07760 d67bfe16f55c33f0acdd7250a454ba10 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 120 134 2.2E-43 T 06-07-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GTHT12_RS07760 d67bfe16f55c33f0acdd7250a454ba10 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 164 181 2.2E-43 T 06-07-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GTHT12_RS07760 d67bfe16f55c33f0acdd7250a454ba10 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 63 71 2.2E-43 T 06-07-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GTHT12_RS07760 d67bfe16f55c33f0acdd7250a454ba10 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 89 106 2.2E-43 T 06-07-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GTHT12_RS07760 d67bfe16f55c33f0acdd7250a454ba10 269 SUPERFAMILY SSF53613 10 256 7.79E-60 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS07760 d67bfe16f55c33f0acdd7250a454ba10 269 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 13 261 34.073 T 06-07-2017 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GTHT12_RS16510 69f8f59120795681d184b77804e6edef 337 Pfam PF13407 Periplasmic binding protein domain 52 306 7.9E-56 T 06-07-2017 IPR025997 Periplasmic binding protein GTHT12_RS16510 69f8f59120795681d184b77804e6edef 337 SUPERFAMILY SSF53822 49 333 2.36E-64 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS16510 69f8f59120795681d184b77804e6edef 337 Gene3D G3DSA:3.40.50.2300 44 167 4.4E-33 T 06-07-2017 GTHT12_RS16510 69f8f59120795681d184b77804e6edef 337 Gene3D G3DSA:3.40.50.2300 168 317 4.3E-46 T 06-07-2017 GTHT12_RS06440 1b7afb6f85445d9b75cfbce4949c6222 348 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 4 347 39.642 T 06-07-2017 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 GTHT12_RS06440 1b7afb6f85445d9b75cfbce4949c6222 348 Pfam PF00072 Response regulator receiver domain 6 110 1.1E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS06440 1b7afb6f85445d9b75cfbce4949c6222 348 SUPERFAMILY SSF52738 161 346 1.96E-62 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 GTHT12_RS06440 1b7afb6f85445d9b75cfbce4949c6222 348 Pfam PF01339 CheB methylesterase 162 342 8.2E-60 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 GTHT12_RS06440 1b7afb6f85445d9b75cfbce4949c6222 348 Gene3D G3DSA:3.40.50.2300 2 110 3.6E-32 T 06-07-2017 GTHT12_RS06440 1b7afb6f85445d9b75cfbce4949c6222 348 Gene3D G3DSA:3.40.50.180 158 346 3.2E-73 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 GTHT12_RS06440 1b7afb6f85445d9b75cfbce4949c6222 348 PIRSF PIRSF000876 1 348 6.4E-136 T 06-07-2017 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 GTHT12_RS06440 1b7afb6f85445d9b75cfbce4949c6222 348 SMART SM00448 4 127 3.2E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS06440 1b7afb6f85445d9b75cfbce4949c6222 348 SUPERFAMILY SSF52172 1 109 4.84E-31 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS10340 ebf9b086a6fb08981cad942f4233ae88 447 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 7 446 2.9E-155 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 GTHT12_RS10340 ebf9b086a6fb08981cad942f4233ae88 447 PIRSF PIRSF002746 1 447 2.1E-175 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 GTHT12_RS10340 ebf9b086a6fb08981cad942f4233ae88 447 Pfam PF02447 GntP family permease 7 444 4.7E-165 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 GTHT12_RS08035 b101501c0c479c94e72b466168429d36 175 Gene3D G3DSA:3.40.30.10 5 171 3.6E-50 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS08035 b101501c0c479c94e72b466168429d36 175 SUPERFAMILY SSF52833 35 168 6.24E-43 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS08035 b101501c0c479c94e72b466168429d36 175 ProSitePatterns PS00194 Thioredoxin family active site. 67 85 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 GTHT12_RS08035 b101501c0c479c94e72b466168429d36 175 Pfam PF00578 AhpC/TSA family 39 156 4.6E-31 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GTHT12_RS09350 a80ac8015ca8b797553e19bd5b5a0809 394 Pfam PF00155 Aminotransferase class I and II 31 380 1.4E-58 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 GTHT12_RS09350 a80ac8015ca8b797553e19bd5b5a0809 394 Gene3D G3DSA:3.40.640.10 45 255 9.7E-58 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS09350 a80ac8015ca8b797553e19bd5b5a0809 394 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 GTHT12_RS09350 a80ac8015ca8b797553e19bd5b5a0809 394 Gene3D G3DSA:3.90.1150.10 256 381 3.8E-39 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS09350 a80ac8015ca8b797553e19bd5b5a0809 394 SUPERFAMILY SSF53383 3 381 5.42E-106 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS17775 c458093abe3a2d1ad6d31d4c88f77d21 142 Pfam PF07486 Cell Wall Hydrolase 24 131 3.0E-17 T 06-07-2017 IPR011105 Cell wall hydrolase, SleB GO:0016787 GTHT12_RS01305 9aae82e66622a76cf202e7737638a03a 129 Gene3D G3DSA:3.90.470.20 1 116 1.3E-43 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 GTHT12_RS01305 9aae82e66622a76cf202e7737638a03a 129 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 117 27.152 T 06-07-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 GTHT12_RS01305 9aae82e66622a76cf202e7737638a03a 129 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 118 2.0E-49 T 06-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 GTHT12_RS01305 9aae82e66622a76cf202e7737638a03a 129 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 1 117 1.7E-33 T 06-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 GTHT12_RS01305 9aae82e66622a76cf202e7737638a03a 129 SUPERFAMILY SSF56214 1 116 3.14E-38 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 GTHT12_RS01305 9aae82e66622a76cf202e7737638a03a 129 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 117 1.1E-37 T 06-07-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 GTHT12_RS01305 9aae82e66622a76cf202e7737638a03a 129 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 112 1.1E-26 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 GTHT12_RS00925 c3266b8a4be2b6805c4f6187aa2994e9 203 Pfam PF13490 Putative zinc-finger 3 38 4.0E-10 T 06-07-2017 IPR027383 Putative zinc-finger GTHT12_RS16900 87070b91d278e8e1c7a9c1ec99eb1cb2 248 SUPERFAMILY SSF46689 2 73 1.79E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS16900 87070b91d278e8e1c7a9c1ec99eb1cb2 248 SUPERFAMILY SSF53697 88 245 1.57E-30 T 06-07-2017 GTHT12_RS16900 87070b91d278e8e1c7a9c1ec99eb1cb2 248 Gene3D G3DSA:3.40.50.10490 64 244 4.6E-32 T 06-07-2017 GTHT12_RS16900 87070b91d278e8e1c7a9c1ec99eb1cb2 248 Gene3D G3DSA:1.10.10.10 3 63 6.2E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS16900 87070b91d278e8e1c7a9c1ec99eb1cb2 248 Pfam PF01380 SIS domain 112 211 5.3E-19 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 GTHT12_RS16900 87070b91d278e8e1c7a9c1ec99eb1cb2 248 Pfam PF01418 Helix-turn-helix domain, rpiR family 4 73 1.0E-15 T 06-07-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 GTHT12_RS08285 9a2d103d58db6e3ce1f70ba51ec983c0 68 Pfam PF14044 NETI protein 9 63 1.0E-26 T 06-07-2017 IPR025930 NETI protein GTHT12_RS06825 e13bb9a364b0d53196ad1669766793c9 539 Gene3D G3DSA:3.30.300.30 432 531 7.4E-29 T 06-07-2017 GTHT12_RS06825 e13bb9a364b0d53196ad1669766793c9 539 Gene3D G3DSA:3.40.50.980 186 338 1.5E-38 T 06-07-2017 GTHT12_RS06825 e13bb9a364b0d53196ad1669766793c9 539 Pfam PF00501 AMP-binding enzyme 20 435 2.8E-94 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 GTHT12_RS06825 e13bb9a364b0d53196ad1669766793c9 539 Gene3D G3DSA:3.40.50.980 42 185 4.6E-28 T 06-07-2017 GTHT12_RS06825 e13bb9a364b0d53196ad1669766793c9 539 Pfam PF13193 AMP-binding enzyme C-terminal domain 445 519 9.3E-20 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain GTHT12_RS06825 e13bb9a364b0d53196ad1669766793c9 539 Gene3D G3DSA:2.30.38.10 356 429 2.2E-20 T 06-07-2017 GTHT12_RS06825 e13bb9a364b0d53196ad1669766793c9 539 SUPERFAMILY SSF56801 11 532 1.7E-141 T 06-07-2017 GTHT12_RS04920 e98a8e884451a608bf3e092e0b1aff23 386 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 357 3.5E-83 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 GTHT12_RS04920 e98a8e884451a608bf3e092e0b1aff23 386 Pfam PF07687 Peptidase dimerisation domain 177 267 2.7E-12 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS04920 e98a8e884451a608bf3e092e0b1aff23 386 Gene3D G3DSA:3.40.630.10 2 166 1.4E-63 T 06-07-2017 GTHT12_RS04920 e98a8e884451a608bf3e092e0b1aff23 386 Gene3D G3DSA:3.40.630.10 281 372 1.4E-63 T 06-07-2017 GTHT12_RS04920 e98a8e884451a608bf3e092e0b1aff23 386 SUPERFAMILY SSF53187 3 185 2.03E-60 T 06-07-2017 GTHT12_RS04920 e98a8e884451a608bf3e092e0b1aff23 386 SUPERFAMILY SSF53187 284 370 2.03E-60 T 06-07-2017 GTHT12_RS04920 e98a8e884451a608bf3e092e0b1aff23 386 Gene3D G3DSA:3.30.70.360 175 276 3.0E-23 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS04920 e98a8e884451a608bf3e092e0b1aff23 386 SUPERFAMILY SSF55031 177 276 9.42E-24 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS04920 e98a8e884451a608bf3e092e0b1aff23 386 PIRSF PIRSF005962 1 374 2.0E-92 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 GTHT12_RS04920 e98a8e884451a608bf3e092e0b1aff23 386 Pfam PF01546 Peptidase family M20/M25/M40 69 368 1.8E-22 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 GTHT12_RS05200 45ab0085b4c27e01fe0d3a0b0ad93167 126 Gene3D G3DSA:1.10.357.10 16 99 1.9E-4 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 GTHT12_RS05200 45ab0085b4c27e01fe0d3a0b0ad93167 126 ProDom PD020942 TRANSPOSASE C TN554 TRANSPOSON TRANSPOSITION FOR DNA-BINDING TRANSPOSABLE DNA ELEMENT 21 123 2.0E-37 T 06-07-2017 GTHT12_RS08270 abcfba1a856868b31748f9ad9b345faa 212 SUPERFAMILY SSF51230 41 111 4.19E-6 T 06-07-2017 IPR011053 Single hybrid motif GTHT12_RS08270 abcfba1a856868b31748f9ad9b345faa 212 Pfam PF00529 HlyD membrane-fusion protein of T1SS 26 199 6.3E-8 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 GTHT12_RS08270 abcfba1a856868b31748f9ad9b345faa 212 Gene3D G3DSA:2.40.50.100 45 112 6.1E-7 T 06-07-2017 GTHT12_RS08270 abcfba1a856868b31748f9ad9b345faa 212 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 80 158 3.5E-15 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain GTHT12_RS14045 7c79faa99e4fde653df58211e177ab9d 179 Pfam PF02674 Colicin V production protein 2 164 2.1E-39 T 06-07-2017 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 GTHT12_RS11270 c0635ab311f6730e8cd0e0c118a3192b 281 SUPERFAMILY SSF161098 65 263 4.58E-8 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS11270 c0635ab311f6730e8cd0e0c118a3192b 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 268 2.6E-6 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS11270 c0635ab311f6730e8cd0e0c118a3192b 281 Gene3D G3DSA:1.10.3720.10 63 268 8.7E-6 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS09650 1af8db2f01ca56ab105bf59b5ec9ffd2 298 SUPERFAMILY SSF109998 116 273 6.67E-5 T 06-07-2017 IPR027304 Trigger factor/SurA domain GTHT12_RS09650 1af8db2f01ca56ab105bf59b5ec9ffd2 298 Pfam PF13115 YtkA-like 16 93 8.7E-11 T 06-07-2017 IPR032693 YtkA-like domain GTHT12_RS06225 ba9199d74f634fa34b2a54674ce933ca 78 Hamap MF_00088 UPF0109 protein . 1 75 21.087 T 06-07-2017 IPR020627 Uncharacterised protein family UPF0109 GTHT12_RS06225 ba9199d74f634fa34b2a54674ce933ca 78 Pfam PF13083 KH domain 4 74 3.0E-23 T 06-07-2017 GTHT12_RS06225 ba9199d74f634fa34b2a54674ce933ca 78 Gene3D G3DSA:3.30.300.120 13 72 3.8E-8 T 06-07-2017 GTHT12_RS06225 ba9199d74f634fa34b2a54674ce933ca 78 SUPERFAMILY SSF54814 7 59 2.42E-7 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 GTHT12_RS08015 068f23696f43b1c229d273d49ab33373 1242 Gene3D G3DSA:3.40.50.300 636 682 1.5E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08015 068f23696f43b1c229d273d49ab33373 1242 Gene3D G3DSA:3.40.50.300 125 227 1.9E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08015 068f23696f43b1c229d273d49ab33373 1242 Gene3D G3DSA:3.40.50.300 46 82 1.9E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08015 068f23696f43b1c229d273d49ab33373 1242 Gene3D G3DSA:3.40.50.300 796 912 1.5E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08015 068f23696f43b1c229d273d49ab33373 1242 Pfam PF00350 Dynamin family 51 205 1.4E-25 T 06-07-2017 IPR022812 Dynamin superfamily GTHT12_RS08015 068f23696f43b1c229d273d49ab33373 1242 Pfam PF00350 Dynamin family 650 876 1.6E-38 T 06-07-2017 IPR022812 Dynamin superfamily GTHT12_RS08015 068f23696f43b1c229d273d49ab33373 1242 SUPERFAMILY SSF52540 33 303 2.89E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08015 068f23696f43b1c229d273d49ab33373 1242 SUPERFAMILY SSF52540 789 914 1.45E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08015 068f23696f43b1c229d273d49ab33373 1242 SUPERFAMILY SSF52540 632 700 1.45E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17245 19deee4d12dfd26f01659b9b2ad7313e 392 SUPERFAMILY SSF56112 121 319 8.16E-7 T 06-07-2017 IPR011009 Protein kinase-like domain GTHT12_RS17245 19deee4d12dfd26f01659b9b2ad7313e 392 Gene3D G3DSA:3.90.1200.10 210 313 1.1E-5 T 06-07-2017 GTHT12_RS12925 c3002e9dd26792f47f7f778a8e5fc48e 103 Pfam PF01476 LysM domain 48 99 2.2E-4 T 06-07-2017 IPR018392 LysM domain GTHT12_RS12925 c3002e9dd26792f47f7f778a8e5fc48e 103 ProDom PD067165 YQFZ MEMBRANE WALL BH1402 TRANSMEMBRANE OB1935 CELL 1 101 2.0E-22 T 06-07-2017 IPR020506 Uncharacterised protein family YqfZ GTHT12_RS12925 c3002e9dd26792f47f7f778a8e5fc48e 103 Gene3D G3DSA:3.10.350.10 48 99 5.7E-5 T 06-07-2017 IPR018392 LysM domain GTHT12_RS05735 6c25bdb3fd4f8fda5cf0b2a18a886066 141 Pfam PF00571 CBS domain 68 118 8.7E-17 T 06-07-2017 IPR000644 CBS domain GTHT12_RS05735 6c25bdb3fd4f8fda5cf0b2a18a886066 141 Pfam PF00571 CBS domain 4 54 1.2E-12 T 06-07-2017 IPR000644 CBS domain GTHT12_RS05735 6c25bdb3fd4f8fda5cf0b2a18a886066 141 SUPERFAMILY SSF54631 2 119 5.81E-36 T 06-07-2017 GTHT12_RS05735 6c25bdb3fd4f8fda5cf0b2a18a886066 141 SMART SM00116 11 58 3.4E-9 T 06-07-2017 IPR000644 CBS domain GTHT12_RS05735 6c25bdb3fd4f8fda5cf0b2a18a886066 141 SMART SM00116 75 122 2.1E-14 T 06-07-2017 IPR000644 CBS domain GTHT12_RS05735 6c25bdb3fd4f8fda5cf0b2a18a886066 141 Gene3D G3DSA:3.10.580.10 3 118 2.4E-38 T 06-07-2017 GTHT12_RS12245 ff3921b45adf0a16444b9b636e6cd5af 306 PRINTS PR00069 Aldo-keto reductase signature 103 121 4.2E-6 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GTHT12_RS12245 ff3921b45adf0a16444b9b636e6cd5af 306 PRINTS PR00069 Aldo-keto reductase signature 37 61 4.2E-6 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GTHT12_RS12245 ff3921b45adf0a16444b9b636e6cd5af 306 PRINTS PR00069 Aldo-keto reductase signature 134 151 4.2E-6 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GTHT12_RS12245 ff3921b45adf0a16444b9b636e6cd5af 306 SUPERFAMILY SSF51430 1 298 1.03E-80 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain GTHT12_RS12245 ff3921b45adf0a16444b9b636e6cd5af 306 Pfam PF00248 Aldo/keto reductase family 15 296 1.6E-62 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain GTHT12_RS12245 ff3921b45adf0a16444b9b636e6cd5af 306 Gene3D G3DSA:3.20.20.100 1 302 5.9E-80 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain GTHT12_RS02370 644ead6e17b85fe8537414580e7b2857 239 Pfam PF02754 Cysteine-rich domain 3 84 5.2E-18 T 06-07-2017 IPR004017 Cysteine-rich domain GTHT12_RS02370 644ead6e17b85fe8537414580e7b2857 239 Pfam PF02754 Cysteine-rich domain 132 215 4.5E-17 T 06-07-2017 IPR004017 Cysteine-rich domain GTHT12_RS02370 644ead6e17b85fe8537414580e7b2857 239 Hamap MF_02105 Lactate utilization protein A [lutA]. 1 238 64.14 T 06-07-2017 IPR022822 Lactate utilization protein A GO:0006089 GTHT12_RS09955 bcbff61032fb80b65d48c3304973c672 331 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 122 4.9E-23 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 GTHT12_RS09955 bcbff61032fb80b65d48c3304973c672 331 Gene3D G3DSA:3.30.360.10 144 331 5.4E-40 T 06-07-2017 GTHT12_RS09955 bcbff61032fb80b65d48c3304973c672 331 Gene3D G3DSA:3.40.50.720 2 143 1.8E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS09955 bcbff61032fb80b65d48c3304973c672 331 SUPERFAMILY SSF51735 3 157 1.61E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS09955 bcbff61032fb80b65d48c3304973c672 331 SUPERFAMILY SSF55347 129 297 9.81E-44 T 06-07-2017 GTHT12_RS05095 f8a1946da5c5fcc7ca521e66672bdad7 474 Pfam PF13520 Amino acid permease 7 435 4.9E-50 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 GTHT12_RS05095 f8a1946da5c5fcc7ca521e66672bdad7 474 PIRSF PIRSF006060 1 471 2.0E-55 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 GTHT12_RS05560 e57ff3fd6283d698c3db0ea06e26348b 71 Hamap MF_01553 UPF0356 protein . 1 69 24.071 T 06-07-2017 IPR009907 Protein of unknown function DUF1447 GTHT12_RS05560 e57ff3fd6283d698c3db0ea06e26348b 71 ProDom PD055417 UPF0356 TRANSCRIPTIONAL REGULATOR SP0122 SH1862 BLI01669/BL01628 MW0973 LMOF2365_1049 BCE33L3734 SPYM3_1619/SPS0248 1 68 1.0E-30 T 06-07-2017 IPR009907 Protein of unknown function DUF1447 GTHT12_RS05560 e57ff3fd6283d698c3db0ea06e26348b 71 Pfam PF07288 Protein of unknown function (DUF1447) 2 68 1.2E-31 T 06-07-2017 IPR009907 Protein of unknown function DUF1447 GTHT12_RS05655 fb83cea1a6e95c463b8a876b538ac5d7 197 TIGRFAM TIGR02898 spore_YhcN_YlaJ: sporulation lipoprotein, YhcN/YlaJ family 8 154 2.1E-37 T 06-07-2017 IPR014247 Sporulation lipoprotein YhcN/YlaJ GTHT12_RS05655 fb83cea1a6e95c463b8a876b538ac5d7 197 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 30 152 2.8E-17 T 06-07-2017 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like GTHT12_RS12830 b9d49854b7e0d35d63d1aaa3d3095c46 487 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 24 478 5.7E-158 T 06-07-2017 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 GTHT12_RS12830 b9d49854b7e0d35d63d1aaa3d3095c46 487 PIRSF PIRSF005690 7 487 6.4E-133 T 06-07-2017 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 GTHT12_RS16855 648a2c4e0691e4365bccffd93ba3ec8e 158 SUPERFAMILY SSF54427 42 153 2.15E-7 T 06-07-2017 IPR032710 NTF2-like domain GTHT12_RS11695 5e0f919e67771959b89608314a57e407 259 Pfam PF07307 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 17 220 3.0E-74 T 06-07-2017 IPR009920 Heptaprenyl diphosphate synthase subunit 1 GO:0009234 KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 GTHT12_RS16330 d85f571debbe1b959b80a2c1b2b65811 245 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 60 225 4.0E-62 T 06-07-2017 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 GTHT12_RS16330 d85f571debbe1b959b80a2c1b2b65811 245 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 56 231 7.5E-58 T 06-07-2017 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 GTHT12_RS09805 080c073deb12193cb230871b6c951391 535 Gene3D G3DSA:2.60.120.200 329 534 1.1E-69 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain GTHT12_RS09805 080c073deb12193cb230871b6c951391 535 SUPERFAMILY SSF75005 4 322 2.86E-109 T 06-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain GTHT12_RS09805 080c073deb12193cb230871b6c951391 535 Pfam PF04616 Glycosyl hydrolases family 43 4 302 3.9E-110 T 06-07-2017 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 GTHT12_RS09805 080c073deb12193cb230871b6c951391 535 SUPERFAMILY SSF49899 327 534 1.82E-69 T 06-07-2017 IPR013320 Concanavalin A-like lectin/glucanase domain GTHT12_RS09805 080c073deb12193cb230871b6c951391 535 Gene3D G3DSA:2.115.10.20 4 323 6.0E-102 T 06-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain GTHT12_RS16215 35ade211076983fbb192e7d4cbd3ea8f 144 Pfam PF02623 FliW protein 20 137 4.6E-40 T 06-07-2017 IPR003775 Flagellar assembly factor FliW GO:0044780 GTHT12_RS16215 35ade211076983fbb192e7d4cbd3ea8f 144 SUPERFAMILY SSF141457 1 140 4.84E-49 T 06-07-2017 IPR024046 Flagellar assembly factor FliW domain GTHT12_RS16215 35ade211076983fbb192e7d4cbd3ea8f 144 Hamap MF_01185 Flagellar assembly factor FliW [fliW]. 17 140 26.818 T 06-07-2017 IPR003775 Flagellar assembly factor FliW GO:0044780 GTHT12_RS16215 35ade211076983fbb192e7d4cbd3ea8f 144 Gene3D G3DSA:2.30.290.10 1 141 7.9E-56 T 06-07-2017 IPR024046 Flagellar assembly factor FliW domain GTHT12_RS07005 1edc8aec51a1c24668b1bf365f352486 308 SUPERFAMILY SSF103481 40 141 1.31E-9 T 06-07-2017 GTHT12_RS07005 1edc8aec51a1c24668b1bf365f352486 308 SUPERFAMILY SSF103481 193 293 4.97E-15 T 06-07-2017 GTHT12_RS07005 1edc8aec51a1c24668b1bf365f352486 308 Pfam PF00892 EamA-like transporter family 149 287 1.2E-19 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 GTHT12_RS07005 1edc8aec51a1c24668b1bf365f352486 308 Pfam PF00892 EamA-like transporter family 8 139 1.2E-18 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 GTHT12_RS09260 21903e67544dce99539af201aa7e50ac 194 Pfam PF12822 Protein of unknown function (DUF3816) 8 176 6.4E-22 T 06-07-2017 IPR024529 ECF transporter, substrate-specific component GO:0005215 GTHT12_RS09260 21903e67544dce99539af201aa7e50ac 194 PIRSF PIRSF037778 2 189 5.7E-45 T 06-07-2017 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 GTHT12_RS14705 4eb9e43c85afd7922951a370c61df70a 73 Gene3D G3DSA:1.10.10.10 14 61 8.3E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS14705 4eb9e43c85afd7922951a370c61df70a 73 SMART SM00420 11 56 0.0018 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 GTHT12_RS14705 4eb9e43c85afd7922951a370c61df70a 73 Pfam PF08220 DeoR-like helix-turn-helix domain 11 53 2.7E-9 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 GTHT12_RS14705 4eb9e43c85afd7922951a370c61df70a 73 SUPERFAMILY SSF46785 11 60 1.41E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS01565 2cca1ff39500032e7a0cf5c69a9a90f9 180 SUPERFAMILY SSF55729 5 174 4.33E-48 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS01565 2cca1ff39500032e7a0cf5c69a9a90f9 180 Pfam PF13302 Acetyltransferase (GNAT) domain 10 149 2.5E-25 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS01565 2cca1ff39500032e7a0cf5c69a9a90f9 180 Gene3D G3DSA:3.40.630.30 7 175 3.1E-51 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS07720 d0ea9236edd77e1d818aa21be8264dfa 326 SUPERFAMILY SSF50891 182 297 4.93E-13 T 06-07-2017 IPR029000 Cyclophilin-like domain GTHT12_RS07720 d0ea9236edd77e1d818aa21be8264dfa 326 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 1 308 9.1E-100 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B GTHT12_RS07720 d0ea9236edd77e1d818aa21be8264dfa 326 Pfam PF02626 Allophanate hydrolase subunit 2 25 291 1.1E-97 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B GTHT12_RS07720 d0ea9236edd77e1d818aa21be8264dfa 326 SMART SM00797 23 307 3.0E-144 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B GTHT12_RS07720 d0ea9236edd77e1d818aa21be8264dfa 326 Gene3D G3DSA:2.40.100.10 186 301 2.5E-9 T 06-07-2017 IPR029000 Cyclophilin-like domain GTHT12_RS16380 eb7949770e34260a3f1ccaed8296dcdb 401 SUPERFAMILY SSF53756 98 386 4.93E-24 T 06-07-2017 GTHT12_RS16380 eb7949770e34260a3f1ccaed8296dcdb 401 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 29 386 2.8E-78 T 06-07-2017 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 GTHT12_RS15545 b50d99ca789654fb5efa168404cd8aae 396 SUPERFAMILY SSF53822 42 388 4.19E-98 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS15545 b50d99ca789654fb5efa168404cd8aae 396 Pfam PF13458 Periplasmic binding protein 44 387 1.6E-68 T 06-07-2017 IPR028081 Leucine-binding protein domain GTHT12_RS15545 b50d99ca789654fb5efa168404cd8aae 396 Gene3D G3DSA:3.40.50.2300 43 245 2.4E-62 T 06-07-2017 GTHT12_RS17770 d3f285fbb3fe09a9b74f267b462a2fa4 248 Hamap MF_01442 Putative heme-dependent peroxidase . 1 248 55.886 T 06-07-2017 IPR031332 Putative heme-dependent peroxidase, UPF0447 family GTHT12_RS17770 d3f285fbb3fe09a9b74f267b462a2fa4 248 SUPERFAMILY SSF54909 1 247 1.98E-94 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel GTHT12_RS17770 d3f285fbb3fe09a9b74f267b462a2fa4 248 Gene3D G3DSA:3.30.70.1030 1 143 4.8E-59 T 06-07-2017 GTHT12_RS17770 d3f285fbb3fe09a9b74f267b462a2fa4 248 Gene3D G3DSA:3.30.70.1100 144 247 8.7E-48 T 06-07-2017 GTHT12_RS17770 d3f285fbb3fe09a9b74f267b462a2fa4 248 Pfam PF06778 Chlorite dismutase 33 237 1.8E-75 T 06-07-2017 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase GTHT12_RS09975 d8548198b77fae63d489e7178804123e 435 Pfam PF01547 Bacterial extracellular solute-binding protein 49 337 3.3E-38 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 GTHT12_RS09975 d8548198b77fae63d489e7178804123e 435 SUPERFAMILY SSF53850 20 434 3.43E-64 T 06-07-2017 GTHT12_RS09975 d8548198b77fae63d489e7178804123e 435 Gene3D G3DSA:3.40.190.10 157 364 4.7E-38 T 06-07-2017 GTHT12_RS02205 3eb979709bfd9715fc2028235bc65921 389 Gene3D G3DSA:3.30.360.10 331 381 6.0E-34 T 06-07-2017 GTHT12_RS02205 3eb979709bfd9715fc2028235bc65921 389 Gene3D G3DSA:3.30.360.10 150 268 6.0E-34 T 06-07-2017 GTHT12_RS02205 3eb979709bfd9715fc2028235bc65921 389 SUPERFAMILY SSF51735 8 162 1.01E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS02205 3eb979709bfd9715fc2028235bc65921 389 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 9 133 3.2E-19 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 GTHT12_RS02205 3eb979709bfd9715fc2028235bc65921 389 Gene3D G3DSA:3.40.50.720 8 149 1.8E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS02205 3eb979709bfd9715fc2028235bc65921 389 SUPERFAMILY SSF55347 139 270 5.23E-13 T 06-07-2017 GTHT12_RS02205 3eb979709bfd9715fc2028235bc65921 389 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 147 204 6.2E-5 T 06-07-2017 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 GTHT12_RS06630 ee5bebf1e08c615a8acd0e014f3c2ec7 245 Gene3D G3DSA:3.90.226.10 42 220 8.3E-25 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS06630 ee5bebf1e08c615a8acd0e014f3c2ec7 245 Pfam PF00574 Clp protease 44 220 3.8E-35 T 06-07-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA GTHT12_RS06630 ee5bebf1e08c615a8acd0e014f3c2ec7 245 SUPERFAMILY SSF52096 29 228 3.92E-40 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS12250 1095d0ed4713059e02ec497dbc57963e 399 SUPERFAMILY SSF103473 16 387 6.93E-46 T 06-07-2017 IPR020846 Major facilitator superfamily domain GTHT12_RS12250 1095d0ed4713059e02ec497dbc57963e 399 Gene3D G3DSA:1.20.1250.20 22 190 1.4E-15 T 06-07-2017 GTHT12_RS12250 1095d0ed4713059e02ec497dbc57963e 399 Gene3D G3DSA:1.20.1250.20 213 384 9.7E-17 T 06-07-2017 GTHT12_RS12250 1095d0ed4713059e02ec497dbc57963e 399 Pfam PF07690 Major Facilitator Superfamily 32 229 2.0E-18 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 GTHT12_RS10290 fa72af257b347b9d827c7a214673e0fa 254 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 253 2.2E-53 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 GTHT12_RS10290 fa72af257b347b9d827c7a214673e0fa 254 Gene3D G3DSA:3.90.226.10 2 191 7.4E-56 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS10290 fa72af257b347b9d827c7a214673e0fa 254 Gene3D G3DSA:1.10.12.10 196 254 5.8E-20 T 06-07-2017 IPR014748 Crontonase, C-terminal GTHT12_RS10290 fa72af257b347b9d827c7a214673e0fa 254 SUPERFAMILY SSF52096 1 254 1.56E-74 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS08560 3b0c360ffc31c7e3d8b4513c90fad8b5 287 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 274 4.6E-47 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 GTHT12_RS13640 309a672da08a9b80e0a644a66dbde4de 286 Pfam PF02163 Peptidase family M50 115 167 2.1E-7 T 06-07-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 GTHT12_RS11945 721fc83c9041466caabbd5bc0691ab71 216 Gene3D G3DSA:3.40.50.1240 6 188 4.4E-36 T 06-07-2017 IPR029033 Histidine phosphatase superfamily GTHT12_RS11945 721fc83c9041466caabbd5bc0691ab71 216 SMART SM00855 6 159 1.5E-15 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 GTHT12_RS11945 721fc83c9041466caabbd5bc0691ab71 216 SUPERFAMILY SSF53254 7 191 3.34E-38 T 06-07-2017 IPR029033 Histidine phosphatase superfamily GTHT12_RS11945 721fc83c9041466caabbd5bc0691ab71 216 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 186 8.4E-35 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 GTHT12_RS00020 39ff72a6cb1bbaabfddb2431cd5cb001 372 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 2 365 7.4E-128 T 06-07-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 GTHT12_RS00020 39ff72a6cb1bbaabfddb2431cd5cb001 372 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 372 106.003 T 06-07-2017 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 GTHT12_RS00020 39ff72a6cb1bbaabfddb2431cd5cb001 372 SUPERFAMILY SSF52540 2 217 1.64E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00020 39ff72a6cb1bbaabfddb2431cd5cb001 372 SUPERFAMILY SSF52540 244 348 1.64E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00020 39ff72a6cb1bbaabfddb2431cd5cb001 372 ProSitePatterns PS00618 RecF protein signature 2. 312 330 - T 06-07-2017 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 GTHT12_RS00020 39ff72a6cb1bbaabfddb2431cd5cb001 372 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 06-07-2017 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 GTHT12_RS00020 39ff72a6cb1bbaabfddb2431cd5cb001 372 Gene3D G3DSA:3.40.50.300 3 165 4.8E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00020 39ff72a6cb1bbaabfddb2431cd5cb001 372 Gene3D G3DSA:3.40.50.300 239 352 4.8E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS00020 39ff72a6cb1bbaabfddb2431cd5cb001 372 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 346 7.4E-18 T 06-07-2017 IPR003395 RecF/RecN/SMC, N-terminal GTHT12_RS05780 c72ce0cac63a8a949f30b1853b47f2ff 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 4.1E-53 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 GTHT12_RS05780 c72ce0cac63a8a949f30b1853b47f2ff 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 4.1E-53 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 GTHT12_RS05780 c72ce0cac63a8a949f30b1853b47f2ff 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 4.1E-53 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 GTHT12_RS05780 c72ce0cac63a8a949f30b1853b47f2ff 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 4.1E-53 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 GTHT12_RS05780 c72ce0cac63a8a949f30b1853b47f2ff 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 4.1E-53 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 GTHT12_RS05780 c72ce0cac63a8a949f30b1853b47f2ff 164 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 158 6.6E-65 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 GTHT12_RS05780 c72ce0cac63a8a949f30b1853b47f2ff 164 Gene3D G3DSA:3.40.50.620 2 158 3.8E-57 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS05780 c72ce0cac63a8a949f30b1853b47f2ff 164 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 4 69 7.0E-4 T 06-07-2017 GTHT12_RS05780 c72ce0cac63a8a949f30b1853b47f2ff 164 Pfam PF01467 Cytidylyltransferase-like 7 134 3.2E-20 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 GTHT12_RS05780 c72ce0cac63a8a949f30b1853b47f2ff 164 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 60 2.8E-18 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 GTHT12_RS05780 c72ce0cac63a8a949f30b1853b47f2ff 164 SUPERFAMILY SSF52374 4 157 5.09E-45 T 06-07-2017 GTHT12_RS05780 c72ce0cac63a8a949f30b1853b47f2ff 164 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 159 36.903 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 GTHT12_RS05705 3075593b9919ef0805bfa692c846049b 206 Gene3D G3DSA:1.20.120.80 25 203 4.2E-51 T 06-07-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05705 3075593b9919ef0805bfa692c846049b 206 SUPERFAMILY SSF81452 21 203 3.14E-54 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS05705 3075593b9919ef0805bfa692c846049b 206 Pfam PF00510 Cytochrome c oxidase subunit III 28 203 5.7E-18 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS07250 252baabaa349cc83ca87829f41a9bfec 279 Pfam PF00753 Metallo-beta-lactamase superfamily 41 177 3.0E-16 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS07250 252baabaa349cc83ca87829f41a9bfec 279 SMART SM00849 34 203 6.4E-22 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS07250 252baabaa349cc83ca87829f41a9bfec 279 SUPERFAMILY SSF56281 41 252 2.54E-39 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS07250 252baabaa349cc83ca87829f41a9bfec 279 Gene3D G3DSA:3.60.15.10 43 228 4.4E-31 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS09465 ca969996f5452a30ccadcd621208dd07 265 SMART SM00382 31 239 1.4E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS09465 ca969996f5452a30ccadcd621208dd07 265 Pfam PF00005 ABC transporter 22 170 3.9E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS09465 ca969996f5452a30ccadcd621208dd07 265 Gene3D G3DSA:3.40.50.300 5 233 6.4E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS09465 ca969996f5452a30ccadcd621208dd07 265 SUPERFAMILY SSF52540 5 232 3.76E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13595 5af62847fa3a7084302073967d2b1776 381 Gene3D G3DSA:3.90.1150.10 245 370 5.6E-31 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS13595 5af62847fa3a7084302073967d2b1776 381 SUPERFAMILY SSF53383 1 373 2.69E-95 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS13595 5af62847fa3a7084302073967d2b1776 381 Pfam PF00266 Aminotransferase class-V 2 364 1.1E-74 T 06-07-2017 IPR000192 Aminotransferase class V domain GTHT12_RS13595 5af62847fa3a7084302073967d2b1776 381 PIRSF PIRSF005572 1 378 3.0E-117 T 06-07-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 GTHT12_RS13595 5af62847fa3a7084302073967d2b1776 381 Gene3D G3DSA:3.40.640.10 14 244 2.2E-72 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS16315 dd6b851fb63ff5f6ef167baa6787e222 374 SUPERFAMILY SSF53756 4 367 6.28E-74 T 06-07-2017 GTHT12_RS16315 dd6b851fb63ff5f6ef167baa6787e222 374 Pfam PF00534 Glycosyl transferases group 1 181 331 2.4E-36 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 GTHT12_RS16315 dd6b851fb63ff5f6ef167baa6787e222 374 Gene3D G3DSA:3.40.50.2000 181 343 3.3E-24 T 06-07-2017 GTHT12_RS16315 dd6b851fb63ff5f6ef167baa6787e222 374 Pfam PF13439 Glycosyltransferase Family 4 13 169 1.4E-17 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 GTHT12_RS03580 e1398637a5bbb66a16c0bbb70b950205 377 PIRSF PIRSF032178 1 377 9.0E-131 T 06-07-2017 IPR016991 Protein of unknown function UCP032178 GTHT12_RS03580 e1398637a5bbb66a16c0bbb70b950205 377 Pfam PF04286 Protein of unknown function (DUF445) 12 375 1.1E-76 T 06-07-2017 IPR007383 Protein of unknown function DUF445 GTHT12_RS07845 3811685a4bdb28cc4cb8de57c2847798 266 Pfam PF12679 ABC-2 family transporter protein 45 264 5.7E-11 T 06-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 GTHT12_RS06660 b27d4c53a1c623f139fa589764258135 509 SMART SM00382 29 217 2.2E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS06660 b27d4c53a1c623f139fa589764258135 509 SMART SM00382 282 509 22.0 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS06660 b27d4c53a1c623f139fa589764258135 509 SUPERFAMILY SSF52540 239 491 1.68E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06660 b27d4c53a1c623f139fa589764258135 509 SUPERFAMILY SSF52540 3 227 6.8E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06660 b27d4c53a1c623f139fa589764258135 509 ProSitePatterns PS00211 ABC transporters family signature. 402 416 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS06660 b27d4c53a1c623f139fa589764258135 509 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS06660 b27d4c53a1c623f139fa589764258135 509 Pfam PF00005 ABC transporter 21 169 2.9E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS06660 b27d4c53a1c623f139fa589764258135 509 Pfam PF00005 ABC transporter 274 429 1.2E-17 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS06660 b27d4c53a1c623f139fa589764258135 509 Gene3D G3DSA:3.40.50.300 3 229 1.3E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06660 b27d4c53a1c623f139fa589764258135 509 Gene3D G3DSA:3.40.50.300 253 493 3.2E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11250 65a97270370646711c864af1ef0c56f9 248 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS11250 65a97270370646711c864af1ef0c56f9 248 Pfam PF00005 ABC transporter 21 160 7.5E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS11250 65a97270370646711c864af1ef0c56f9 248 Gene3D G3DSA:3.40.50.300 3 215 1.9E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS11250 65a97270370646711c864af1ef0c56f9 248 SMART SM00382 29 209 5.2E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS11250 65a97270370646711c864af1ef0c56f9 248 SUPERFAMILY SSF52540 4 216 1.57E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS09185 ceb3e8eeb124cb2d27a58d7b175c14f0 558 Pfam PF01636 Phosphotransferase enzyme family 255 311 9.2E-6 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase GTHT12_RS09185 ceb3e8eeb124cb2d27a58d7b175c14f0 558 SUPERFAMILY SSF56112 96 159 1.57E-35 T 06-07-2017 IPR011009 Protein kinase-like domain GTHT12_RS09185 ceb3e8eeb124cb2d27a58d7b175c14f0 558 SUPERFAMILY SSF56112 194 311 1.57E-35 T 06-07-2017 IPR011009 Protein kinase-like domain GTHT12_RS09185 ceb3e8eeb124cb2d27a58d7b175c14f0 558 SUPERFAMILY SSF56112 351 416 1.57E-35 T 06-07-2017 IPR011009 Protein kinase-like domain GTHT12_RS09185 ceb3e8eeb124cb2d27a58d7b175c14f0 558 Gene3D G3DSA:3.90.1200.10 243 312 3.2E-11 T 06-07-2017 GTHT12_RS09185 ceb3e8eeb124cb2d27a58d7b175c14f0 558 Pfam PF03109 ABC1 family 114 231 1.1E-38 T 06-07-2017 IPR004147 UbiB domain GTHT12_RS18030 6820f6fd516224759b5d4dac44016504 215 PRINTS PR00164 ABC-2 type transport system membrane protein signature 15 37 4.6E-5 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 GTHT12_RS18030 6820f6fd516224759b5d4dac44016504 215 PRINTS PR00164 ABC-2 type transport system membrane protein signature 133 152 4.6E-5 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 GTHT12_RS18030 6820f6fd516224759b5d4dac44016504 215 PRINTS PR00164 ABC-2 type transport system membrane protein signature 96 120 4.6E-5 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 GTHT12_RS18030 6820f6fd516224759b5d4dac44016504 215 PIRSF PIRSF006648 2 210 2.0E-18 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 GTHT12_RS18030 6820f6fd516224759b5d4dac44016504 215 Pfam PF01061 ABC-2 type transporter 17 174 3.3E-24 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 GTHT12_RS18430 eb9fa2a9509cc8e9fa65406765aec36a 344 Gene3D G3DSA:3.40.1780.10 1 66 6.7E-79 T 06-07-2017 GTHT12_RS18430 eb9fa2a9509cc8e9fa65406765aec36a 344 Gene3D G3DSA:3.40.1780.10 182 344 6.7E-79 T 06-07-2017 GTHT12_RS18430 eb9fa2a9509cc8e9fa65406765aec36a 344 SUPERFAMILY SSF111337 1 344 3.4E-99 T 06-07-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 GTHT12_RS18430 eb9fa2a9509cc8e9fa65406765aec36a 344 Pfam PF02547 Queuosine biosynthesis protein 4 343 4.5E-94 T 06-07-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 GTHT12_RS18430 eb9fa2a9509cc8e9fa65406765aec36a 344 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 344 6.6E-81 T 06-07-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 GTHT12_RS16355 f9957670ed7f2e298ab0092f0a306390 557 Gene3D G3DSA:3.40.50.300 2 247 2.4E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16355 f9957670ed7f2e298ab0092f0a306390 557 SMART SM00382 49 235 2.4E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS16355 f9957670ed7f2e298ab0092f0a306390 557 SUPERFAMILY SSF52540 30 237 5.99E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16355 f9957670ed7f2e298ab0092f0a306390 557 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS16355 f9957670ed7f2e298ab0092f0a306390 557 Pfam PF00005 ABC transporter 40 171 1.4E-20 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS17665 f09d02473e5caeaf34720531fc15b3c8 698 Gene3D G3DSA:1.10.1060.10 347 395 9.4E-35 T 06-07-2017 GTHT12_RS17665 f09d02473e5caeaf34720531fc15b3c8 698 Gene3D G3DSA:1.10.1060.10 248 312 9.4E-35 T 06-07-2017 GTHT12_RS17665 f09d02473e5caeaf34720531fc15b3c8 698 Pfam PF13183 4Fe-4S dicluster domain 273 377 7.2E-12 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain GTHT12_RS17665 f09d02473e5caeaf34720531fc15b3c8 698 Gene3D G3DSA:1.20.950.20 18 235 1.7E-9 T 06-07-2017 GTHT12_RS17665 f09d02473e5caeaf34720531fc15b3c8 698 SUPERFAMILY SSF46548 257 312 1.17E-19 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 GTHT12_RS17665 f09d02473e5caeaf34720531fc15b3c8 698 SUPERFAMILY SSF46548 347 393 1.17E-19 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 GTHT12_RS17665 f09d02473e5caeaf34720531fc15b3c8 698 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 276 287 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GTHT12_RS17665 f09d02473e5caeaf34720531fc15b3c8 698 SUPERFAMILY SSF103501 8 238 1.7E-14 T 06-07-2017 IPR023234 NarG-like domain GTHT12_RS17665 f09d02473e5caeaf34720531fc15b3c8 698 Pfam PF02754 Cysteine-rich domain 575 662 1.8E-18 T 06-07-2017 IPR004017 Cysteine-rich domain GTHT12_RS17665 f09d02473e5caeaf34720531fc15b3c8 698 Pfam PF02754 Cysteine-rich domain 453 534 7.8E-7 T 06-07-2017 IPR004017 Cysteine-rich domain GTHT12_RS17665 f09d02473e5caeaf34720531fc15b3c8 698 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 365 376 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GTHT12_RS16325 3358537827032a5209f4ea8eab64affb 448 Pfam PF13425 O-antigen ligase like membrane protein 3 437 2.1E-101 T 06-07-2017 GTHT12_RS08240 39e712fed13404a60b08b01d33c82153 70 Gene3D G3DSA:2.40.50.100 2 70 1.2E-26 T 06-07-2017 GTHT12_RS08240 39e712fed13404a60b08b01d33c82153 70 SUPERFAMILY SSF51230 3 70 1.96E-23 T 06-07-2017 IPR011053 Single hybrid motif GTHT12_RS08240 39e712fed13404a60b08b01d33c82153 70 Pfam PF00364 Biotin-requiring enzyme 6 69 1.4E-19 T 06-07-2017 IPR000089 Biotin/lipoyl attachment GTHT12_RS00800 a561972f1e035a4e68cdd5d2b538a256 120 ProSitePatterns PS01167 Ribosomal protein L17 signature. 30 52 - T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00800 a561972f1e035a4e68cdd5d2b538a256 120 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 120 29.244 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00800 a561972f1e035a4e68cdd5d2b538a256 120 Pfam PF01196 Ribosomal protein L17 16 120 3.7E-40 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00800 a561972f1e035a4e68cdd5d2b538a256 120 TIGRFAM TIGR00059 L17: ribosomal protein bL17 2 120 5.9E-49 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00800 a561972f1e035a4e68cdd5d2b538a256 120 Gene3D G3DSA:3.90.1030.10 2 120 3.1E-50 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00800 a561972f1e035a4e68cdd5d2b538a256 120 SUPERFAMILY SSF64263 2 120 1.31E-45 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS08335 d31db892bd6f69d288f035ffd0f24c5b 293 SMART SM00382 26 204 2.6E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS08335 d31db892bd6f69d288f035ffd0f24c5b 293 Pfam PF00005 ABC transporter 18 154 8.6E-22 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS08335 d31db892bd6f69d288f035ffd0f24c5b 293 SUPERFAMILY SSF52540 2 217 1.03E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08335 d31db892bd6f69d288f035ffd0f24c5b 293 Gene3D G3DSA:3.40.50.300 1 216 8.7E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS16745 c54f59731a9d5bcb68eaa87616e7d27c 706 Gene3D G3DSA:3.10.450.50 2 23 4.3E-8 T 06-07-2017 IPR032710 NTF2-like domain GTHT12_RS16745 c54f59731a9d5bcb68eaa87616e7d27c 706 SUPERFAMILY SSF103642 3 24 5.56E-8 T 06-07-2017 GTHT12_RS16745 c54f59731a9d5bcb68eaa87616e7d27c 706 Pfam PF02810 SEC-C motif 5 22 3.9E-10 T 06-07-2017 IPR004027 SEC-C motif GTHT12_RS05720 beb8169df2e6f53f6b8525d4079a8b11 151 Pfam PF04238 Protein of unknown function (DUF420) 4 132 8.2E-40 T 06-07-2017 IPR007352 Protein of unknown function DUF420 GTHT12_RS15360 d1cab90fba3d77246d0c7122ef7f6c3f 138 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 5 129 2.4E-33 T 06-07-2017 IPR007182 Na+/H+ antiporter MnhB subunit-related protein GTHT12_RS12845 78f324a0288ce7301bd06c15956b8c63 245 Gene3D G3DSA:3.40.50.1000 94 231 5.1E-30 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS12845 78f324a0288ce7301bd06c15956b8c63 245 SUPERFAMILY SSF56784 5 214 1.52E-37 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS12845 78f324a0288ce7301bd06c15956b8c63 245 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 119 200 4.2E-9 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 GTHT12_RS12845 78f324a0288ce7301bd06c15956b8c63 245 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 204 4.3E-20 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS12845 78f324a0288ce7301bd06c15956b8c63 245 Gene3D G3DSA:1.10.150.240 24 93 6.4E-5 T 06-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 GTHT12_RS08265 27f82cf2ffd8d0ca855a739cdfa10b0b 146 Gene3D G3DSA:1.10.10.10 7 141 1.6E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS08265 27f82cf2ffd8d0ca855a739cdfa10b0b 146 SMART SM00347 25 128 1.0E-18 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS08265 27f82cf2ffd8d0ca855a739cdfa10b0b 146 SUPERFAMILY SSF46785 7 140 1.37E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS08265 27f82cf2ffd8d0ca855a739cdfa10b0b 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 4.3E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS08265 27f82cf2ffd8d0ca855a739cdfa10b0b 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 4.3E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS08265 27f82cf2ffd8d0ca855a739cdfa10b0b 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 4.3E-7 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS08265 27f82cf2ffd8d0ca855a739cdfa10b0b 146 Pfam PF01047 MarR family 32 90 4.2E-15 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 GTHT12_RS08265 27f82cf2ffd8d0ca855a739cdfa10b0b 146 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 98 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site GTHT12_RS16735 f3c58e21a9278f819043f1f21b6e5c72 436 Pfam PF05525 Branched-chain amino acid transport protein 3 426 7.9E-156 T 06-07-2017 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 GTHT12_RS16735 f3c58e21a9278f819043f1f21b6e5c72 436 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 10 413 1.5E-138 T 06-07-2017 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 GTHT12_RS13475 5f9648ee1bdf62e9a6ecac027f459fd7 152 SUPERFAMILY SSF69500 1 145 7.19E-60 T 06-07-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain GTHT12_RS13475 5f9648ee1bdf62e9a6ecac027f459fd7 152 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 9.7E-63 T 06-07-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 GTHT12_RS13475 5f9648ee1bdf62e9a6ecac027f459fd7 152 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 36.731 T 06-07-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 GTHT12_RS13475 5f9648ee1bdf62e9a6ecac027f459fd7 152 Gene3D G3DSA:3.50.80.10 1 145 5.5E-62 T 06-07-2017 IPR023509 D-Tyr tRNAtyr deacylase-like domain GTHT12_RS13475 5f9648ee1bdf62e9a6ecac027f459fd7 152 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 8.6E-58 T 06-07-2017 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 GTHT12_RS03575 b8f927fce31419a0ea70acca568b9095 358 Pfam PF14398 YheC/D like ATP-grasp 103 353 5.0E-75 T 06-07-2017 IPR026838 Endospore coat-associated protein YheC/D GTHT12_RS03575 b8f927fce31419a0ea70acca568b9095 358 Gene3D G3DSA:3.30.470.20 288 337 1.5E-4 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 GTHT12_RS03575 b8f927fce31419a0ea70acca568b9095 358 SUPERFAMILY SSF56059 126 350 1.24E-21 T 06-07-2017 GTHT12_RS03575 b8f927fce31419a0ea70acca568b9095 358 Gene3D G3DSA:3.30.1490.20 131 176 6.9E-9 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 GTHT12_RS16350 2a21406a32a23eadce32783a7fac3fe3 387 Pfam PF00534 Glycosyl transferases group 1 208 362 4.1E-36 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 GTHT12_RS16350 2a21406a32a23eadce32783a7fac3fe3 387 SUPERFAMILY SSF53756 6 384 2.47E-64 T 06-07-2017 GTHT12_RS16350 2a21406a32a23eadce32783a7fac3fe3 387 Gene3D G3DSA:3.40.50.2000 209 361 1.5E-20 T 06-07-2017 GTHT12_RS08650 c63975440a6e7e4929e84409950aa7d7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.3E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08650 c63975440a6e7e4929e84409950aa7d7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.3E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08650 c63975440a6e7e4929e84409950aa7d7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 3.3E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08650 c63975440a6e7e4929e84409950aa7d7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 3.3E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08650 c63975440a6e7e4929e84409950aa7d7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.3E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08650 c63975440a6e7e4929e84409950aa7d7 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 3.3E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08650 c63975440a6e7e4929e84409950aa7d7 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 246 2.0E-73 T 06-07-2017 GTHT12_RS08650 c63975440a6e7e4929e84409950aa7d7 250 Gene3D G3DSA:3.40.50.720 2 246 7.1E-92 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS08650 c63975440a6e7e4929e84409950aa7d7 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08650 c63975440a6e7e4929e84409950aa7d7 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08650 c63975440a6e7e4929e84409950aa7d7 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.6E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS08650 c63975440a6e7e4929e84409950aa7d7 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 GTHT12_RS08650 c63975440a6e7e4929e84409950aa7d7 250 SUPERFAMILY SSF51735 4 246 1.93E-87 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS01785 76c8b6cc9322737ff5422737f5b72368 209 SUPERFAMILY SSF161098 12 199 1.57E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS01785 76c8b6cc9322737ff5422737f5b72368 209 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 205 3.6E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS01785 76c8b6cc9322737ff5422737f5b72368 209 Gene3D G3DSA:1.10.3720.10 9 198 2.5E-34 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS14030 80d5cdaa718728dc7a7a0a6e1c345527 135 Pfam PF03994 Domain of Unknown Function (DUF350) 80 131 1.1E-13 T 06-07-2017 IPR007140 Protein of unknown function DUF350 GTHT12_RS14030 80d5cdaa718728dc7a7a0a6e1c345527 135 Pfam PF03994 Domain of Unknown Function (DUF350) 17 67 8.0E-13 T 06-07-2017 IPR007140 Protein of unknown function DUF350 GTHT12_RS05665 cbae70dc00679d0ef9cb2be71f4d7b7a 168 ProDom PD094668 YLAL SIMILAR MW0994 BH2628 SE0810 SA0960 4 167 2.0E-78 T 06-07-2017 IPR020229 Uncharacterised protein YlaL GTHT12_RS03370 525a9f3607756782a70503223435a396 132 ProDom PD081567 YHCU 1 112 5.0E-53 T 06-07-2017 IPR020355 Uncharacterised protein family YhcU GTHT12_RS07285 bc1351790a84aaa0a2da0a1255b02e42 553 Gene3D G3DSA:2.50.20.10 108 294 1.1E-12 T 06-07-2017 GTHT12_RS07285 bc1351790a84aaa0a2da0a1255b02e42 553 Pfam PF03888 MucB/RseB N-terminal domain 144 259 9.9E-6 T 06-07-2017 IPR033434 MucB/RseB, N-terminal GTHT12_RS07285 bc1351790a84aaa0a2da0a1255b02e42 553 SUPERFAMILY SSF89392 108 295 1.26E-12 T 06-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX GTHT12_RS13155 ccc81bb6bffcb0c93fe8cda71ef66052 399 SUPERFAMILY SSF53187 262 385 1.48E-6 T 06-07-2017 GTHT12_RS13155 ccc81bb6bffcb0c93fe8cda71ef66052 399 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 182 385 2.6E-76 T 06-07-2017 IPR010897 Sporulation stage II, protein P GTHT12_RS13155 ccc81bb6bffcb0c93fe8cda71ef66052 399 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 104 381 1.0E-76 T 06-07-2017 IPR010897 Sporulation stage II, protein P GTHT12_RS09310 538006712117915c5531dd5ce62fcd5e 201 SUPERFAMILY SSF52833 37 197 4.84E-44 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS09310 538006712117915c5531dd5ce62fcd5e 201 Pfam PF02630 SCO1/SenC 24 181 1.9E-41 T 06-07-2017 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS09310 538006712117915c5531dd5ce62fcd5e 201 Gene3D G3DSA:3.40.30.10 17 197 7.4E-53 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS03450 2b0cd0d8b2a4c5a0867e8256ee4b53c3 692 Pfam PF02554 Carbon starvation protein CstA 32 408 1.4E-171 T 06-07-2017 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 GTHT12_RS03450 2b0cd0d8b2a4c5a0867e8256ee4b53c3 692 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 463 591 6.3E-36 T 06-07-2017 IPR025299 CstA, C-terminal domain GTHT12_RS07735 3eaa369fe6f629740e50ded1b62baace 278 Gene3D G3DSA:3.40.50.1000 14 38 9.5E-4 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS07735 3eaa369fe6f629740e50ded1b62baace 278 SUPERFAMILY SSF56784 2 249 2.49E-31 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS07735 3eaa369fe6f629740e50ded1b62baace 278 Pfam PF00702 haloacid dehalogenase-like hydrolase 6 243 4.1E-10 T 06-07-2017 GTHT12_RS07735 3eaa369fe6f629740e50ded1b62baace 278 Gene3D G3DSA:3.40.50.1000 151 276 6.2E-24 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS07735 3eaa369fe6f629740e50ded1b62baace 278 Gene3D G3DSA:3.40.50.1000 5 13 6.2E-24 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS04510 bc80d49241be56a34b2492287c9489b0 158 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 33 137 1.2E-9 T 06-07-2017 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like GTHT12_RS14360 313b903f68d262020a3b1bf641ce8b0c 170 Gene3D G3DSA:3.40.980.10 6 168 9.2E-49 T 06-07-2017 IPR001453 MoaB/Mog domain GTHT12_RS14360 313b903f68d262020a3b1bf641ce8b0c 170 PIRSF PIRSF006443 1 170 2.7E-66 T 06-07-2017 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 GTHT12_RS14360 313b903f68d262020a3b1bf641ce8b0c 170 Pfam PF00994 Probable molybdopterin binding domain 18 161 8.6E-35 T 06-07-2017 IPR001453 MoaB/Mog domain GTHT12_RS14360 313b903f68d262020a3b1bf641ce8b0c 170 SUPERFAMILY SSF53218 7 167 8.9E-43 T 06-07-2017 IPR001453 MoaB/Mog domain GTHT12_RS14360 313b903f68d262020a3b1bf641ce8b0c 170 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 157 2.8E-36 T 06-07-2017 IPR001453 MoaB/Mog domain GTHT12_RS14360 313b903f68d262020a3b1bf641ce8b0c 170 SMART SM00852 17 162 1.3E-29 T 06-07-2017 IPR001453 MoaB/Mog domain GTHT12_RS14360 313b903f68d262020a3b1bf641ce8b0c 170 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 75 88 - T 06-07-2017 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 GTHT12_RS08450 6d8c22b79542f8553498a97e66a3c5db 183 SUPERFAMILY SSF53697 5 182 7.08E-36 T 06-07-2017 GTHT12_RS08450 6d8c22b79542f8553498a97e66a3c5db 183 Gene3D G3DSA:3.40.50.10490 8 182 1.2E-42 T 06-07-2017 GTHT12_RS08450 6d8c22b79542f8553498a97e66a3c5db 183 Pfam PF01380 SIS domain 31 133 1.5E-19 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 GTHT12_RS08450 6d8c22b79542f8553498a97e66a3c5db 183 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 6 183 8.1E-65 T 06-07-2017 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 GTHT12_RS08555 23714cf45dbd21a9896107694bbe07c1 193 Gene3D G3DSA:1.10.10.60 34 51 4.9E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS08555 23714cf45dbd21a9896107694bbe07c1 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 5 50 5.7E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS08555 23714cf45dbd21a9896107694bbe07c1 193 SUPERFAMILY SSF46689 2 67 1.18E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS08555 23714cf45dbd21a9896107694bbe07c1 193 Gene3D G3DSA:1.10.10.60 2 33 1.2E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS08555 23714cf45dbd21a9896107694bbe07c1 193 SUPERFAMILY SSF48498 74 186 1.95E-26 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal GTHT12_RS08555 23714cf45dbd21a9896107694bbe07c1 193 Gene3D G3DSA:1.10.357.10 52 188 4.6E-44 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 GTHT12_RS08555 23714cf45dbd21a9896107694bbe07c1 193 Pfam PF08359 YsiA-like protein, C-terminal region 62 152 1.2E-5 T 06-07-2017 IPR013570 Transcription regulator YsiA, C-terminal GTHT12_RS08555 23714cf45dbd21a9896107694bbe07c1 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 7.9E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS08555 23714cf45dbd21a9896107694bbe07c1 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 7.9E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 GTHT12_RS04950 3deb7e5b57a637983de0988497db519c 246 Pfam PF04542 Sigma-70 region 2 31 101 9.6E-9 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS04950 3deb7e5b57a637983de0988497db519c 246 Gene3D G3DSA:1.10.1740.10 12 119 1.2E-9 T 06-07-2017 GTHT12_RS04950 3deb7e5b57a637983de0988497db519c 246 PIRSF PIRSF038953 3 246 4.1E-72 T 06-07-2017 IPR014244 RNA polymerase sigma-I type GTHT12_RS04950 3deb7e5b57a637983de0988497db519c 246 TIGRFAM TIGR02895 spore_sigI: RNA polymerase sigma-I factor 17 240 3.3E-96 T 06-07-2017 IPR014244 RNA polymerase sigma-I type GTHT12_RS04950 3deb7e5b57a637983de0988497db519c 246 SUPERFAMILY SSF88946 19 99 2.2E-18 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 GTHT12_RS02425 6cd09e145dde08b80ba4ef10a48e23d0 217 SUPERFAMILY SSF102588 3 214 6.15E-58 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 GTHT12_RS02425 6cd09e145dde08b80ba4ef10a48e23d0 217 TIGRFAM TIGR04000 thiol_BshB2: bacillithiol biosynthesis deacetylase BshB2 4 215 5.4E-111 T 06-07-2017 IPR023841 Bacillithiol biosynthesis deacetylase BshB2 GTHT12_RS02425 6cd09e145dde08b80ba4ef10a48e23d0 217 Gene3D G3DSA:3.40.50.10320 2 214 8.8E-58 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 GTHT12_RS02425 6cd09e145dde08b80ba4ef10a48e23d0 217 Pfam PF02585 GlcNAc-PI de-N-acetylase 7 136 5.6E-31 T 06-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 GTHT12_RS01940 43f62433b0670f87e143174adb1e4eb2 306 Gene3D G3DSA:3.40.50.10330 44 93 7.4E-5 T 06-07-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 GTHT12_RS01940 43f62433b0670f87e143174adb1e4eb2 306 SUPERFAMILY SSF111331 1 297 1.8E-83 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain GTHT12_RS01940 43f62433b0670f87e143174adb1e4eb2 306 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 296 5.6E-108 T 06-07-2017 IPR005218 Diacylglycerol/lipid kinase GTHT12_RS01940 43f62433b0670f87e143174adb1e4eb2 306 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 127 1.0E-37 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 GTHT12_RS01940 43f62433b0670f87e143174adb1e4eb2 306 SMART SM00046 3 130 6.6E-7 T 06-07-2017 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 GTHT12_RS02100 e3d979c7f8bebf02f4812968b95cce58 246 ProSitePatterns PS01007 Transposases, Mutator family, signature. 78 102 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS02100 e3d979c7f8bebf02f4812968b95cce58 246 Pfam PF00872 Transposase, Mutator family 1 223 1.3E-60 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS17855 3f291cbdf5badcbc059de3832c830929 164 Gene3D G3DSA:2.70.70.10 8 159 1.7E-65 T 06-07-2017 GTHT12_RS17855 3f291cbdf5badcbc059de3832c830929 164 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 16 136 1.9E-49 T 06-07-2017 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 GTHT12_RS17855 3f291cbdf5badcbc059de3832c830929 164 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 15 138 1.4E-54 T 06-07-2017 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 GTHT12_RS17855 3f291cbdf5badcbc059de3832c830929 164 SUPERFAMILY SSF51261 5 160 1.31E-58 T 06-07-2017 IPR011055 Duplicated hybrid motif GTHT12_RS17855 3f291cbdf5badcbc059de3832c830929 164 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 78 90 - T 06-07-2017 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 GTHT12_RS09785 8e75530bbe997b8bb28950f450eeb092 395 Gene3D G3DSA:1.20.1090.10 186 385 1.3E-67 T 06-07-2017 GTHT12_RS09785 8e75530bbe997b8bb28950f450eeb092 395 SUPERFAMILY SSF56796 6 388 9.81E-120 T 06-07-2017 GTHT12_RS09785 8e75530bbe997b8bb28950f450eeb092 395 Pfam PF00465 Iron-containing alcohol dehydrogenase 13 377 1.1E-119 T 06-07-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 GTHT12_RS09785 8e75530bbe997b8bb28950f450eeb092 395 Gene3D G3DSA:3.40.50.1970 6 185 3.8E-53 T 06-07-2017 GTHT12_RS09785 8e75530bbe997b8bb28950f450eeb092 395 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 174 202 - T 06-07-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 GTHT12_RS08415 d0f330e212cc43a31d651898861a3a28 295 Pfam PF01925 Sulfite exporter TauE/SafE 8 246 1.9E-42 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 GTHT12_RS02510 84815bcb2e302d65be0187e78acb1913 374 Pfam PF08756 YfkB-like domain 220 369 6.4E-77 T 06-07-2017 IPR014866 YfkB-like domain GTHT12_RS02510 84815bcb2e302d65be0187e78acb1913 374 Gene3D G3DSA:3.20.20.70 33 350 2.8E-30 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS02510 84815bcb2e302d65be0187e78acb1913 374 SUPERFAMILY SSF102114 33 330 1.15E-28 T 06-07-2017 GTHT12_RS02510 84815bcb2e302d65be0187e78acb1913 374 Pfam PF04055 Radical SAM superfamily 36 200 9.5E-13 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 GTHT12_RS02510 84815bcb2e302d65be0187e78acb1913 374 TIGRFAM TIGR04478 rSAM_YfkAB: radical SAM/CxCxxxxC motif protein YfkAB 9 369 3.6E-192 T 06-07-2017 IPR031004 Radical SAM/CxCxxxxC motif protein YfkAB GTHT12_RS02510 84815bcb2e302d65be0187e78acb1913 374 Pfam PF13353 4Fe-4S single cluster domain 41 170 8.5E-6 T 06-07-2017 GTHT12_RS17615 5e464f9df6406d766f85833791d8606c 120 SUPERFAMILY SSF52172 4 119 1.01E-38 T 06-07-2017 IPR011006 CheY-like superfamily GTHT12_RS17615 5e464f9df6406d766f85833791d8606c 120 Pfam PF00072 Response regulator receiver domain 5 115 9.0E-32 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS17615 5e464f9df6406d766f85833791d8606c 120 Gene3D G3DSA:3.40.50.2300 4 118 5.2E-37 T 06-07-2017 GTHT12_RS17615 5e464f9df6406d766f85833791d8606c 120 SMART SM00448 3 114 1.4E-32 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 GTHT12_RS10270 9a613e02724ca694d0a00d4dafa4a8db 274 Gene3D G3DSA:1.10.3720.10 3 260 4.4E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS10270 9a613e02724ca694d0a00d4dafa4a8db 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 261 8.5E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS10270 9a613e02724ca694d0a00d4dafa4a8db 274 SUPERFAMILY SSF161098 4 270 4.86E-57 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS16725 9ffaa434860b4683bf81ba00695929e5 409 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 5 405 2.6E-188 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 GTHT12_RS16725 9ffaa434860b4683bf81ba00695929e5 409 Gene3D G3DSA:3.40.630.10 348 407 6.5E-111 T 06-07-2017 GTHT12_RS16725 9ffaa434860b4683bf81ba00695929e5 409 Gene3D G3DSA:3.40.630.10 2 223 6.5E-111 T 06-07-2017 GTHT12_RS16725 9ffaa434860b4683bf81ba00695929e5 409 Pfam PF07687 Peptidase dimerisation domain 208 310 1.9E-11 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS16725 9ffaa434860b4683bf81ba00695929e5 409 SUPERFAMILY SSF55031 211 326 4.19E-29 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS16725 9ffaa434860b4683bf81ba00695929e5 409 Pfam PF01546 Peptidase family M20/M25/M40 75 403 4.0E-32 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 GTHT12_RS16725 9ffaa434860b4683bf81ba00695929e5 409 PIRSF PIRSF001235 2 409 6.0E-146 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 GTHT12_RS16725 9ffaa434860b4683bf81ba00695929e5 409 SUPERFAMILY SSF53187 3 221 2.49E-95 T 06-07-2017 GTHT12_RS16725 9ffaa434860b4683bf81ba00695929e5 409 SUPERFAMILY SSF53187 333 407 2.49E-95 T 06-07-2017 GTHT12_RS16725 9ffaa434860b4683bf81ba00695929e5 409 Gene3D G3DSA:3.30.70.360 224 326 1.2E-36 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain GTHT12_RS09060 647fcdc4e002e6f7286ff337e79b7a28 163 Gene3D G3DSA:3.40.630.30 1 156 3.3E-35 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS09060 647fcdc4e002e6f7286ff337e79b7a28 163 Pfam PF13420 Acetyltransferase (GNAT) domain 3 151 1.0E-19 T 06-07-2017 GTHT12_RS09060 647fcdc4e002e6f7286ff337e79b7a28 163 SUPERFAMILY SSF55729 1 155 2.44E-29 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS15235 43d5919e3257239408fe596323b8e25a 529 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 389 459 5.8E-19 T 06-07-2017 IPR006343 Replication protein, DnaD/DnaB domain GTHT12_RS15235 43d5919e3257239408fe596323b8e25a 529 Pfam PF07261 Replication initiation and membrane attachment 391 459 6.0E-17 T 06-07-2017 IPR006343 Replication protein, DnaD/DnaB domain GTHT12_RS15235 43d5919e3257239408fe596323b8e25a 529 SUPERFAMILY SSF158499 389 453 2.22E-16 T 06-07-2017 IPR006343 Replication protein, DnaD/DnaB domain GTHT12_RS15235 43d5919e3257239408fe596323b8e25a 529 Gene3D G3DSA:1.10.10.630 387 459 3.7E-27 T 06-07-2017 IPR006343 Replication protein, DnaD/DnaB domain GTHT12_RS13045 aaaf97c78e6a9f3069dee8477524dd9d 132 SUPERFAMILY SSF53927 2 130 2.85E-47 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 GTHT12_RS13045 aaaf97c78e6a9f3069dee8477524dd9d 132 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 06-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 GTHT12_RS13045 aaaf97c78e6a9f3069dee8477524dd9d 132 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 101 3.1E-16 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 GTHT12_RS13045 aaaf97c78e6a9f3069dee8477524dd9d 132 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 5 129 4.9E-45 T 06-07-2017 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-73614 GTHT12_RS13045 aaaf97c78e6a9f3069dee8477524dd9d 132 Gene3D G3DSA:3.40.140.10 3 131 1.1E-52 T 06-07-2017 GTHT12_RS03615 cfa8dd3d84128649a222dad53d2abecb 325 SMART SM00471 156 288 2.8E-5 T 06-07-2017 IPR003607 HD/PDEase domain GTHT12_RS03615 cfa8dd3d84128649a222dad53d2abecb 325 SUPERFAMILY SSF109604 143 280 8.79E-14 T 06-07-2017 GTHT12_RS03615 cfa8dd3d84128649a222dad53d2abecb 325 Pfam PF01966 HD domain 161 278 7.3E-11 T 06-07-2017 IPR006674 HD domain GTHT12_RS03615 cfa8dd3d84128649a222dad53d2abecb 325 Gene3D G3DSA:1.10.3210.10 162 278 9.0E-8 T 06-07-2017 IPR006674 HD domain GTHT12_RS03615 cfa8dd3d84128649a222dad53d2abecb 325 Hamap MF_01427 3'-5' exoribonuclease YhaM [yhaM]. 1 313 62.028 T 06-07-2017 IPR020873 3'-5' exoribonuclease YhaM GO:0000175 GTHT12_RS03615 cfa8dd3d84128649a222dad53d2abecb 325 Gene3D G3DSA:2.40.50.140 35 90 1.0E-4 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS03615 cfa8dd3d84128649a222dad53d2abecb 325 SUPERFAMILY SSF50249 31 94 8.05E-7 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold GTHT12_RS16150 8ee1703393efe6ed8b607f08c984a3ef 119 Pfam PF03646 FlaG protein 21 117 3.6E-28 T 06-07-2017 IPR005186 FlaG protein GTHT12_RS16150 8ee1703393efe6ed8b607f08c984a3ef 119 SUPERFAMILY SSF160214 30 119 8.5E-29 T 06-07-2017 IPR005186 FlaG protein GTHT12_RS16150 8ee1703393efe6ed8b607f08c984a3ef 119 Gene3D G3DSA:3.30.160.170 28 115 2.6E-29 T 06-07-2017 IPR005186 FlaG protein GTHT12_RS09695 840fa28d364ee21a8de8ad5a9ee6021d 48 Pfam PF12669 Virus attachment protein p12 family 3 44 3.6E-9 T 06-07-2017 GTHT12_RS13385 365ccfbc54fbfc8c3110dc60431e1983 353 Pfam PF01594 Domain of unknown function DUF20 22 346 3.1E-76 T 06-07-2017 IPR002549 Transmembrane protein TqsA-like GTHT12_RS03010 bf592421f5fe735cac7385651f20392d 334 Gene3D G3DSA:1.10.3720.10 89 162 3.4E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS03010 bf592421f5fe735cac7385651f20392d 334 Gene3D G3DSA:1.10.3720.10 199 329 3.4E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS03010 bf592421f5fe735cac7385651f20392d 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 332 1.5E-44 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS03010 bf592421f5fe735cac7385651f20392d 334 SUPERFAMILY SSF161098 90 159 2.13E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS03010 bf592421f5fe735cac7385651f20392d 334 SUPERFAMILY SSF161098 196 318 2.13E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS13230 2ca538ac96f4acce9c9738dd66d46a60 369 Gene3D G3DSA:3.40.50.300 71 224 1.4E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13230 2ca538ac96f4acce9c9738dd66d46a60 369 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 6 369 2.1E-153 T 06-07-2017 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH GTHT12_RS13230 2ca538ac96f4acce9c9738dd66d46a60 369 SUPERFAMILY SSF52540 64 281 2.33E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS13230 2ca538ac96f4acce9c9738dd66d46a60 369 Pfam PF01926 50S ribosome-binding GTPase 165 226 6.2E-13 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 GTHT12_RS14970 aba48c8668be68d6c9c4f4ad9144a7de 184 Pfam PF00583 Acetyltransferase (GNAT) family 76 156 4.2E-16 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS14970 aba48c8668be68d6c9c4f4ad9144a7de 184 SUPERFAMILY SSF55729 13 182 9.78E-36 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS14970 aba48c8668be68d6c9c4f4ad9144a7de 184 Gene3D G3DSA:3.40.630.30 16 182 1.6E-41 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS09820 21bc17476f1afd3a1ecc15421d12343f 264 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 26 248 9.8E-28 T 06-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 GTHT12_RS09820 21bc17476f1afd3a1ecc15421d12343f 264 Gene3D G3DSA:3.40.1390.30 144 244 5.8E-6 T 06-07-2017 GTHT12_RS09820 21bc17476f1afd3a1ecc15421d12343f 264 Gene3D G3DSA:3.40.1390.30 7 121 6.3E-14 T 06-07-2017 GTHT12_RS09820 21bc17476f1afd3a1ecc15421d12343f 264 SUPERFAMILY SSF102705 26 257 1.06E-38 T 06-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 GTHT12_RS07765 b4b30374e0b78e7789210bd74fd72365 267 Gene3D G3DSA:3.40.1190.20 5 261 1.6E-112 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS07765 b4b30374e0b78e7789210bd74fd72365 267 SUPERFAMILY SSF53613 5 264 1.87E-88 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS07765 b4b30374e0b78e7789210bd74fd72365 267 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 260 2.6E-109 T 06-07-2017 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GTHT12_RS07765 b4b30374e0b78e7789210bd74fd72365 267 Pfam PF08543 Phosphomethylpyrimidine kinase 13 258 2.4E-101 T 06-07-2017 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 GTHT12_RS18680 2d57003fa8e65ea3a92fba70f078395f 356 Pfam PF14020 Protein of unknown function (DUF4236) 3 56 3.0E-20 T 06-07-2017 IPR025330 Domain of unknown function DUF4236 GTHT12_RS12805 2ccfa29d9d6a62e74bf60b4a4dece8fc 210 SMART SM00849 12 190 6.8E-44 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS12805 2ccfa29d9d6a62e74bf60b4a4dece8fc 210 Gene3D G3DSA:3.60.15.10 3 208 1.8E-53 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS12805 2ccfa29d9d6a62e74bf60b4a4dece8fc 210 Pfam PF00753 Metallo-beta-lactamase superfamily 9 190 1.7E-32 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS12805 2ccfa29d9d6a62e74bf60b4a4dece8fc 210 SUPERFAMILY SSF56281 9 205 1.44E-52 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS02325 e476639bd61a73b838477ddd67623607 58 Gene3D G3DSA:1.10.1220.10 3 57 1.9E-7 T 06-07-2017 IPR013321 Arc-type ribbon-helix-helix GO:0006355 GTHT12_RS02325 e476639bd61a73b838477ddd67623607 58 SUPERFAMILY SSF47598 2 53 1.2E-12 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 GTHT12_RS05710 e6987d2c7170288717fcbedd6fa444aa 110 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 29 101 2.0E-15 T 06-07-2017 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 GTHT12_RS05710 e6987d2c7170288717fcbedd6fa444aa 110 TIGRFAM TIGR02908 CoxD_Bacillus: cytochrome c oxidase, subunit IVB 1 110 3.6E-59 T 06-07-2017 IPR014257 Cytochrome c oxidase, subunit IV bacillaceae KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 GTHT12_RS10195 9b3a4a88d41e22fa653e8990b5aadfbc 376 Gene3D G3DSA:1.50.10.10 9 366 3.6E-117 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 GTHT12_RS10195 9b3a4a88d41e22fa653e8990b5aadfbc 376 Pfam PF07470 Glycosyl Hydrolase Family 88 15 360 4.1E-112 T 06-07-2017 IPR010905 Glycosyl hydrolase, family 88 GTHT12_RS10195 9b3a4a88d41e22fa653e8990b5aadfbc 376 SUPERFAMILY SSF48208 19 365 2.15E-76 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 GTHT12_RS16575 d7aa804aed49ee815d1a6d04da2e756c 328 SUPERFAMILY SSF51735 2 152 4.31E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS16575 d7aa804aed49ee815d1a6d04da2e756c 328 Gene3D G3DSA:3.30.360.10 142 327 5.8E-74 T 06-07-2017 GTHT12_RS16575 d7aa804aed49ee815d1a6d04da2e756c 328 SUPERFAMILY SSF55347 126 291 5.72E-29 T 06-07-2017 GTHT12_RS16575 d7aa804aed49ee815d1a6d04da2e756c 328 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 119 9.8E-27 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 GTHT12_RS16575 d7aa804aed49ee815d1a6d04da2e756c 328 Gene3D G3DSA:3.40.50.720 1 141 5.0E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS15540 cb7f468ea5c0a521cd41912a69fa11e6 292 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 276 5.4E-50 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 GTHT12_RS06540 222a3e42cd70e400462b02f3f1b304ef 96 SUPERFAMILY SSF64376 5 88 1.23E-29 T 06-07-2017 IPR007393 Domain of unknown function DUF448 GTHT12_RS06540 222a3e42cd70e400462b02f3f1b304ef 96 Gene3D G3DSA:3.30.1230.10 2 89 9.7E-34 T 06-07-2017 IPR007393 Domain of unknown function DUF448 GTHT12_RS06540 222a3e42cd70e400462b02f3f1b304ef 96 Pfam PF04296 Protein of unknown function (DUF448) 10 82 5.0E-28 T 06-07-2017 IPR007393 Domain of unknown function DUF448 GTHT12_RS09855 db1b149623d9b11eb1f485c1c84b6abc 216 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 6 203 3.6E-51 T 06-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 GTHT12_RS09855 db1b149623d9b11eb1f485c1c84b6abc 216 Gene3D G3DSA:3.20.20.70 2 209 2.9E-69 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS09855 db1b149623d9b11eb1f485c1c84b6abc 216 Pfam PF01081 KDPG and KHG aldolase 6 196 4.9E-41 T 06-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 GTHT12_RS09855 db1b149623d9b11eb1f485c1c84b6abc 216 SUPERFAMILY SSF51569 2 206 2.93E-58 T 06-07-2017 GTHT12_RS06710 eaeefd60231e611bad940c5b7e119f2e 414 PIRSF PIRSF006728 1 414 7.5E-159 T 06-07-2017 IPR008135 Competence-induced protein CinA GTHT12_RS06710 eaeefd60231e611bad940c5b7e119f2e 414 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 2 411 1.9E-150 T 06-07-2017 IPR008135 Competence-induced protein CinA GTHT12_RS06710 eaeefd60231e611bad940c5b7e119f2e 414 Pfam PF00994 Probable molybdopterin binding domain 4 164 7.2E-37 T 06-07-2017 IPR001453 MoaB/Mog domain GTHT12_RS06710 eaeefd60231e611bad940c5b7e119f2e 414 Gene3D G3DSA:3.40.980.10 2 210 2.8E-37 T 06-07-2017 IPR001453 MoaB/Mog domain GTHT12_RS06710 eaeefd60231e611bad940c5b7e119f2e 414 Gene3D G3DSA:3.90.950.20 250 411 2.7E-55 T 06-07-2017 IPR008136 CinA, C-terminal GTHT12_RS06710 eaeefd60231e611bad940c5b7e119f2e 414 SUPERFAMILY SSF53218 2 206 7.2E-43 T 06-07-2017 IPR001453 MoaB/Mog domain GTHT12_RS06710 eaeefd60231e611bad940c5b7e119f2e 414 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 2 162 1.9E-32 T 06-07-2017 IPR001453 MoaB/Mog domain GTHT12_RS06710 eaeefd60231e611bad940c5b7e119f2e 414 SMART SM00852 4 170 2.1E-45 T 06-07-2017 IPR001453 MoaB/Mog domain GTHT12_RS06710 eaeefd60231e611bad940c5b7e119f2e 414 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 414 168.768 T 06-07-2017 IPR008135 Competence-induced protein CinA GTHT12_RS06710 eaeefd60231e611bad940c5b7e119f2e 414 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 264 410 2.4E-39 T 06-07-2017 IPR008136 CinA, C-terminal GTHT12_RS06710 eaeefd60231e611bad940c5b7e119f2e 414 SUPERFAMILY SSF142433 250 410 3.4E-48 T 06-07-2017 IPR008136 CinA, C-terminal GTHT12_RS06710 eaeefd60231e611bad940c5b7e119f2e 414 Pfam PF02464 Competence-damaged protein 257 410 2.5E-50 T 06-07-2017 IPR008136 CinA, C-terminal GTHT12_RS08895 2e06e6ec37d81ddc24016b866ad2b844 297 Pfam PF00795 Carbon-nitrogen hydrolase 5 195 3.8E-29 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 GTHT12_RS08895 2e06e6ec37d81ddc24016b866ad2b844 297 SUPERFAMILY SSF56317 1 277 2.88E-50 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 GTHT12_RS08895 2e06e6ec37d81ddc24016b866ad2b844 297 Gene3D G3DSA:3.60.110.10 1 277 3.6E-52 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 GTHT12_RS15645 fdfdda568d45c6732e1e7acaf47d6230 79 Pfam PF10830 Protein of unknown function (DUF2553) 7 79 6.0E-27 T 06-07-2017 IPR020140 Uncharacterised protein family YusG GTHT12_RS15645 fdfdda568d45c6732e1e7acaf47d6230 79 ProDom PD058325 YUSG BH3483 5 79 4.0E-32 T 06-07-2017 IPR020140 Uncharacterised protein family YusG GTHT12_RS03440 b66736d0724a216cf2efc60c0b900778 230 Pfam PF03741 Integral membrane protein TerC family 14 183 5.4E-47 T 06-07-2017 IPR005496 Integral membrane protein TerC GO:0016021 GTHT12_RS03440 b66736d0724a216cf2efc60c0b900778 230 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 11 184 5.0E-72 T 06-07-2017 IPR022301 Integral membrane protein YjbE GTHT12_RS07510 6a16bd44bf42d67f3069fa234a89165c 170 Pfam PF10710 Protein of unknown function (DUF2512) 1 137 2.3E-44 T 06-07-2017 IPR019649 Protein of unknown function DUF2512 GTHT12_RS16320 d7fbc0e0aa3eb2cdb105bd3e1fc072cf 392 Pfam PF00534 Glycosyl transferases group 1 194 365 7.2E-35 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 GTHT12_RS16320 d7fbc0e0aa3eb2cdb105bd3e1fc072cf 392 Gene3D G3DSA:3.40.50.2000 173 365 8.0E-31 T 06-07-2017 GTHT12_RS16320 d7fbc0e0aa3eb2cdb105bd3e1fc072cf 392 Pfam PF13439 Glycosyltransferase Family 4 15 182 1.6E-22 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 GTHT12_RS16320 d7fbc0e0aa3eb2cdb105bd3e1fc072cf 392 SUPERFAMILY SSF53756 2 384 1.76E-75 T 06-07-2017 GTHT12_RS09085 78faab156c26b08c81d3a09bc1e40fd7 413 SUPERFAMILY SSF64182 2 297 3.4E-29 T 06-07-2017 GTHT12_RS03150 aacb8b3c0478ffdf3031bc1d43aaf074 117 Pfam PF11023 Zinc-ribbon containing domain 4 114 1.7E-60 T 06-07-2017 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 GTHT12_RS03150 aacb8b3c0478ffdf3031bc1d43aaf074 117 ProDom PD355753 MEMBRANE TRANSMEMBRANE UPF0295 BLI00901/BL05075 BT9727_0449 GK0479 BCE0593 YGZB PRECURSOR BA0538/GBAA0538/BAS0506 4 114 1.0E-57 T 06-07-2017 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 GTHT12_RS03150 aacb8b3c0478ffdf3031bc1d43aaf074 117 Hamap MF_01502 UPF0295 protein . 2 116 37.013 T 06-07-2017 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 GTHT12_RS04300 edb521762e07fe1bffc12dfc8f368f37 124 Pfam PF13038 Domain of unknown function (DUF3899) 35 119 8.0E-21 T 06-07-2017 IPR025007 Domain of unknown function DUF3899 GTHT12_RS06730 843d5a7f21339c31b67578f374d1b3cb 86 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 3 86 7.0E-33 T 06-07-2017 IPR007347 Sporulation stage V, protein S GTHT12_RS06730 843d5a7f21339c31b67578f374d1b3cb 86 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 84 8.6E-41 T 06-07-2017 IPR007347 Sporulation stage V, protein S GTHT12_RS03755 1cef9b7f776b99fe58fec9485e19c060 196 SUPERFAMILY SSF52833 36 193 3.01E-36 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS03755 1cef9b7f776b99fe58fec9485e19c060 196 Pfam PF02630 SCO1/SenC 35 174 1.3E-20 T 06-07-2017 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS03755 1cef9b7f776b99fe58fec9485e19c060 196 Gene3D G3DSA:3.40.30.10 6 188 7.2E-42 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS04710 22167d7ca8190b13f069046bee6deb97 73 Pfam PF00872 Transposase, Mutator family 31 69 8.9E-5 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS07020 831874137a7ff2e7b75b61771b73bd9b 89 ProDom PD062992 CYTOSOLIC YPZA BH2151 13 88 4.0E-27 T 06-07-2017 IPR020314 Uncharacterised protein family YpzA GTHT12_RS07020 831874137a7ff2e7b75b61771b73bd9b 89 Pfam PF10819 Protein of unknown function (DUF2564) 11 89 1.0E-36 T 06-07-2017 IPR020314 Uncharacterised protein family YpzA GTHT12_RS07910 29162665924a2500d33662ab45dd5daf 424 Pfam PF13482 RNase_H superfamily 107 275 2.0E-38 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS07910 29162665924a2500d33662ab45dd5daf 424 SUPERFAMILY SSF53098 89 278 3.8E-30 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS07910 29162665924a2500d33662ab45dd5daf 424 Gene3D G3DSA:3.30.420.10 107 282 5.9E-15 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS11875 2288548f5544c7496ff2690b15c76f4f 168 Gene3D G3DSA:3.10.350.10 116 163 1.7E-11 T 06-07-2017 IPR018392 LysM domain GTHT12_RS11875 2288548f5544c7496ff2690b15c76f4f 168 SMART SM00257 117 163 7.7E-11 T 06-07-2017 IPR018392 LysM domain GTHT12_RS11875 2288548f5544c7496ff2690b15c76f4f 168 Pfam PF01476 LysM domain 118 163 4.8E-8 T 06-07-2017 IPR018392 LysM domain GTHT12_RS11875 2288548f5544c7496ff2690b15c76f4f 168 SUPERFAMILY SSF54106 116 163 1.09E-7 T 06-07-2017 IPR018392 LysM domain GTHT12_RS12055 5d8267ec8369edc0014f5ace0c1ab5eb 381 Gene3D G3DSA:3.40.710.10 30 272 5.3E-93 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS12055 5d8267ec8369edc0014f5ace0c1ab5eb 381 SUPERFAMILY SSF56601 1 272 1.2E-71 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like GTHT12_RS12055 5d8267ec8369edc0014f5ace0c1ab5eb 381 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 30 255 8.3E-72 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 GTHT12_RS12055 5d8267ec8369edc0014f5ace0c1ab5eb 381 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 134 147 4.5E-16 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 GTHT12_RS12055 5d8267ec8369edc0014f5ace0c1ab5eb 381 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 59 70 4.5E-16 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 GTHT12_RS12055 5d8267ec8369edc0014f5ace0c1ab5eb 381 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 107 124 4.5E-16 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 GTHT12_RS14620 7532a3bfcf3ccf1951704f8e31bf5d92 149 Pfam PF06103 Bacterial protein of unknown function (DUF948) 8 94 2.6E-20 T 06-07-2017 IPR009293 Uncharacterised protein family UPF0478 GTHT12_RS14620 7532a3bfcf3ccf1951704f8e31bf5d92 149 SUPERFAMILY SSF58104 24 131 2.22E-5 T 06-07-2017 GTHT12_RS14620 7532a3bfcf3ccf1951704f8e31bf5d92 149 Gene3D G3DSA:1.10.287.950 31 100 1.1E-4 T 06-07-2017 GTHT12_RS02615 bbecbd84fd0fe8e2a8c5edcd8d577f5e 643 SUPERFAMILY SSF53474 74 200 1.65E-5 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS02615 bbecbd84fd0fe8e2a8c5edcd8d577f5e 643 SUPERFAMILY SSF53474 233 273 1.65E-5 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS07335 272627ebcce4cfbe2f509ab810832203 315 SUPERFAMILY SSF81345 4 310 3.79E-68 T 06-07-2017 IPR029022 ABC transporter, BtuC-like GTHT12_RS07335 272627ebcce4cfbe2f509ab810832203 315 Gene3D G3DSA:1.10.3470.10 5 311 4.9E-71 T 06-07-2017 IPR029022 ABC transporter, BtuC-like GTHT12_RS07335 272627ebcce4cfbe2f509ab810832203 315 Pfam PF01032 FecCD transport family 8 309 5.7E-67 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 GTHT12_RS12750 f24fbd7cda9c2759eacbae6d7c81c379 59 Pfam PF14038 YqzE-like protein 3 55 2.1E-27 T 06-07-2017 IPR025622 YqzE-like protein GTHT12_RS02565 0da5dce08940168d768f9a1e8e739d86 241 Pfam PF03358 NADPH-dependent FMN reductase 55 159 7.0E-19 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 GTHT12_RS02565 0da5dce08940168d768f9a1e8e739d86 241 Gene3D G3DSA:3.40.50.360 3 236 8.1E-69 T 06-07-2017 IPR029039 Flavoprotein-like domain GTHT12_RS02565 0da5dce08940168d768f9a1e8e739d86 241 SUPERFAMILY SSF52218 33 232 3.64E-31 T 06-07-2017 IPR029039 Flavoprotein-like domain GTHT12_RS13310 ec523f248988a2ca48ee4013627c6919 215 Gene3D G3DSA:3.40.50.150 10 196 7.2E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS13310 ec523f248988a2ca48ee4013627c6919 215 Hamap MF_02100 Uncharacterized methyltransferase . 2 213 46.951 T 06-07-2017 IPR023553 Uncharacterised methyltransferase, YrrT GO:0008168 GTHT12_RS13310 ec523f248988a2ca48ee4013627c6919 215 SUPERFAMILY SSF53335 7 197 1.43E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS13310 ec523f248988a2ca48ee4013627c6919 215 Pfam PF08241 Methyltransferase domain 50 144 7.4E-16 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 GTHT12_RS12575 3d4923b4c0d9061ed85867f2d51d19b1 387 Pfam PF09546 Stage III sporulation protein AE (spore_III_AE) 66 380 1.6E-105 T 06-07-2017 IPR014194 Sporulation stage III, protein AE GTHT12_RS12575 3d4923b4c0d9061ed85867f2d51d19b1 387 TIGRFAM TIGR02829 spore_III_AE: stage III sporulation protein AE 2 380 5.1E-138 T 06-07-2017 IPR014194 Sporulation stage III, protein AE GTHT12_RS06455 5aa3ec5ea3d4802ceab74b1b1b31a0a4 210 Pfam PF04509 CheC-like family 111 145 1.3E-11 T 06-07-2017 IPR007597 CheC-like protein GO:0016787 GTHT12_RS06455 5aa3ec5ea3d4802ceab74b1b1b31a0a4 210 Pfam PF04509 CheC-like family 10 45 3.9E-15 T 06-07-2017 IPR007597 CheC-like protein GO:0016787 GTHT12_RS06455 5aa3ec5ea3d4802ceab74b1b1b31a0a4 210 Gene3D G3DSA:3.40.1550.10 6 206 2.9E-65 T 06-07-2017 IPR028976 CheC-like domain GTHT12_RS06455 5aa3ec5ea3d4802ceab74b1b1b31a0a4 210 SUPERFAMILY SSF103039 6 206 7.46E-53 T 06-07-2017 IPR028976 CheC-like domain GTHT12_RS03600 dd371565d0b5b40e8fc1154131624a2a 61 Pfam PF14120 YhzD-like protein 1 61 1.4E-32 T 06-07-2017 IPR025544 YhzD-like protein GTHT12_RS16890 cf673860e0b10ce19c84fcebdaf5f154 887 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 6 258 1.6E-35 T 06-07-2017 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0005975 GTHT12_RS16890 cf673860e0b10ce19c84fcebdaf5f154 887 SUPERFAMILY SSF74650 369 860 7.22E-59 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 GTHT12_RS16890 cf673860e0b10ce19c84fcebdaf5f154 887 Gene3D G3DSA:1.20.1270.50 287 370 6.5E-6 T 06-07-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 GTHT12_RS16890 cf673860e0b10ce19c84fcebdaf5f154 887 SUPERFAMILY SSF88713 2 223 1.72E-44 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 GTHT12_RS16890 cf673860e0b10ce19c84fcebdaf5f154 887 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 462 860 9.1E-15 T 06-07-2017 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0006013|GO:0015923 GTHT12_RS16890 cf673860e0b10ce19c84fcebdaf5f154 887 Pfam PF09261 Alpha mannosidase middle domain 285 356 1.4E-6 T 06-07-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 GTHT12_RS16890 cf673860e0b10ce19c84fcebdaf5f154 887 SMART SM00872 287 357 7.0E-5 T 06-07-2017 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 GTHT12_RS16890 cf673860e0b10ce19c84fcebdaf5f154 887 Gene3D G3DSA:3.20.110.10 3 196 2.1E-39 T 06-07-2017 IPR027291 Glycoside hydrolase 38/57, N-terminal domain GTHT12_RS16890 cf673860e0b10ce19c84fcebdaf5f154 887 SUPERFAMILY SSF88688 288 374 6.54E-8 T 06-07-2017 IPR028995 Glycoside hydrolase families 57/38, central domain GTHT12_RS03430 f24126a7e22e8cdad77d3ef8ddc3c324 106 Pfam PF00893 Small Multidrug Resistance protein 2 93 1.1E-31 T 06-07-2017 IPR000390 Small multidrug resistance protein family GO:0016021 GTHT12_RS03430 f24126a7e22e8cdad77d3ef8ddc3c324 106 SUPERFAMILY SSF103481 5 102 3.01E-21 T 06-07-2017 GTHT12_RS00665 0c16ac5a7295a61218185979de06bab0 207 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 2.1E-77 T 06-07-2017 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00665 0c16ac5a7295a61218185979de06bab0 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 39.66 T 06-07-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00665 0c16ac5a7295a61218185979de06bab0 207 Gene3D G3DSA:3.40.1370.10 58 207 6.6E-71 T 06-07-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 GTHT12_RS00665 0c16ac5a7295a61218185979de06bab0 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 1.2E-88 T 06-07-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 GTHT12_RS00665 0c16ac5a7295a61218185979de06bab0 207 SUPERFAMILY SSF52166 1 206 2.88E-90 T 06-07-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 GTHT12_RS05510 6088a374bae4067edf1d97a7210fa694 247 Pfam PF01925 Sulfite exporter TauE/SafE 7 238 4.0E-35 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 GTHT12_RS13760 632f1bc6cd1bf247eb9766435a31ca4d 668 SUPERFAMILY SSF53300 188 312 9.11E-30 T 06-07-2017 IPR002035 von Willebrand factor, type A GTHT12_RS13760 632f1bc6cd1bf247eb9766435a31ca4d 668 SUPERFAMILY SSF53300 399 460 9.11E-30 T 06-07-2017 IPR002035 von Willebrand factor, type A GTHT12_RS13760 632f1bc6cd1bf247eb9766435a31ca4d 668 Pfam PF13519 von Willebrand factor type A domain 199 309 1.3E-17 T 06-07-2017 IPR002035 von Willebrand factor, type A GTHT12_RS13760 632f1bc6cd1bf247eb9766435a31ca4d 668 Gene3D G3DSA:3.40.50.410 405 441 1.2E-23 T 06-07-2017 IPR002035 von Willebrand factor, type A GTHT12_RS13760 632f1bc6cd1bf247eb9766435a31ca4d 668 Gene3D G3DSA:3.40.50.410 196 314 1.2E-23 T 06-07-2017 IPR002035 von Willebrand factor, type A GTHT12_RS13760 632f1bc6cd1bf247eb9766435a31ca4d 668 SMART SM00327 196 461 2.0E-24 T 06-07-2017 IPR002035 von Willebrand factor, type A GTHT12_RS09550 97428479296ce7dca91f55bc7e93c3c0 249 Pfam PF12146 Serine aminopeptidase, S33 23 127 4.5E-11 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 GTHT12_RS09550 97428479296ce7dca91f55bc7e93c3c0 249 Pfam PF12146 Serine aminopeptidase, S33 158 229 8.3E-9 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 GTHT12_RS09550 97428479296ce7dca91f55bc7e93c3c0 249 SUPERFAMILY SSF53474 18 248 3.13E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS09550 97428479296ce7dca91f55bc7e93c3c0 249 Gene3D G3DSA:3.40.50.1820 18 248 2.6E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS09550 97428479296ce7dca91f55bc7e93c3c0 249 PIRSF PIRSF017388 5 249 1.4E-81 T 06-07-2017 IPR012354 Esterase/lipase GO:0052689 GTHT12_RS02350 c8049ee402b165f1f8872dd264e458b1 228 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 11 183 1.2E-72 T 06-07-2017 IPR022301 Integral membrane protein YjbE GTHT12_RS02350 c8049ee402b165f1f8872dd264e458b1 228 Pfam PF03741 Integral membrane protein TerC family 14 182 2.9E-47 T 06-07-2017 IPR005496 Integral membrane protein TerC GO:0016021 GTHT12_RS11430 60a78ee7bfb61f4e3ff7ed23507b4a6e 154 Pfam PF00011 Hsp20/alpha crystallin family 57 149 1.6E-9 T 06-07-2017 IPR002068 Alpha crystallin/Hsp20 domain GTHT12_RS11430 60a78ee7bfb61f4e3ff7ed23507b4a6e 154 SUPERFAMILY SSF49764 34 148 1.78E-18 T 06-07-2017 IPR008978 HSP20-like chaperone GTHT12_RS11430 60a78ee7bfb61f4e3ff7ed23507b4a6e 154 Gene3D G3DSA:2.60.40.790 24 148 3.5E-20 T 06-07-2017 IPR008978 HSP20-like chaperone GTHT12_RS17745 ccc69282058ec06730557ae3aa56c7c5 75 Pfam PF07293 Protein of unknown function (DUF1450) 8 73 2.8E-9 T 06-07-2017 IPR009910 Protein of unknown function DUF1450 GTHT12_RS17745 ccc69282058ec06730557ae3aa56c7c5 75 Hamap MF_01863 UPF0741 protein . 1 74 30.084 T 06-07-2017 IPR020880 Protein of unknown function UPF0741 GTHT12_RS02900 fc534eb82a4e259cbb9f51b872a29bef 184 Gene3D G3DSA:3.40.630.30 2 132 7.4E-19 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS02900 fc534eb82a4e259cbb9f51b872a29bef 184 Pfam PF13302 Acetyltransferase (GNAT) domain 6 132 6.2E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS02900 fc534eb82a4e259cbb9f51b872a29bef 184 SUPERFAMILY SSF55729 2 132 1.09E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS02085 b6ed9c9d1a13ff592592c3a054789dd3 136 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 14 132 3.8E-28 T 06-07-2017 IPR006480 Bacteriophage holin family GTHT12_RS02085 b6ed9c9d1a13ff592592c3a054789dd3 136 Pfam PF05105 Bacteriophage holin family 18 130 1.1E-39 T 06-07-2017 IPR006480 Bacteriophage holin family GTHT12_RS01540 9440d9b76a3544de5931359a47a3f122 45 SUPERFAMILY SSF47413 1 45 2.38E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS01540 9440d9b76a3544de5931359a47a3f122 45 Pfam PF01381 Helix-turn-helix 7 45 9.0E-15 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GTHT12_RS01540 9440d9b76a3544de5931359a47a3f122 45 Gene3D G3DSA:1.10.260.40 1 45 1.7E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS07665 0498c74c6c18806fc66e08eac49f6fb4 222 Gene3D G3DSA:3.90.1680.10 1 219 3.5E-77 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) GTHT12_RS07665 0498c74c6c18806fc66e08eac49f6fb4 222 SUPERFAMILY SSF143081 2 219 8.37E-77 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) GTHT12_RS07665 0498c74c6c18806fc66e08eac49f6fb4 222 Pfam PF02586 SOS response associated peptidase (SRAP) 1 207 1.2E-69 T 06-07-2017 IPR003738 SOS response associated peptidase (SRAP) GTHT12_RS12815 5ff3d5ba36239348108323a972b027cc 387 SUPERFAMILY SSF53187 96 387 1.22E-52 T 06-07-2017 GTHT12_RS12815 5ff3d5ba36239348108323a972b027cc 387 SMART SM00631 99 375 8.2E-24 T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 GTHT12_RS12815 5ff3d5ba36239348108323a972b027cc 387 Gene3D G3DSA:3.40.630.10 97 385 3.7E-41 T 06-07-2017 GTHT12_RS12815 5ff3d5ba36239348108323a972b027cc 387 Pfam PF00246 Zinc carboxypeptidase 117 325 9.6E-26 T 06-07-2017 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 GTHT12_RS12615 158a03b6d15f696c5306ca39c1363024 176 Pfam PF11085 Conserved membrane protein YqhR 4 165 1.2E-79 T 06-07-2017 IPR024563 Uncharacterised protein family YqhR GTHT12_RS12615 158a03b6d15f696c5306ca39c1363024 176 ProDom PD101610 MEMBRANE YQHR BH2802 TRANSMEMBRANE IG 8 162 2.0E-69 T 06-07-2017 IPR024563 Uncharacterised protein family YqhR GTHT12_RS06975 0afcbfb847fd25bac54125f01f9f43a9 48 Pfam PF08179 Small acid-soluble spore protein P family 1 43 6.9E-25 T 06-07-2017 IPR012614 Small acid-soluble spore protein, SspP GO:0030435 GTHT12_RS06975 0afcbfb847fd25bac54125f01f9f43a9 48 Hamap MF_00666 Small, acid-soluble spore protein P [sspP]. 1 48 19.019 T 06-07-2017 IPR012614 Small acid-soluble spore protein, SspP GO:0030435 GTHT12_RS13510 dc42a673a7271e2824507c5aa351b97b 520 TIGRFAM TIGR02900 spore_V_B: stage V sporulation protein B 4 491 3.1E-171 T 06-07-2017 IPR014249 Sporulation stage V protein B GTHT12_RS13510 dc42a673a7271e2824507c5aa351b97b 520 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 357 498 1.2E-20 T 06-07-2017 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain GTHT12_RS13510 dc42a673a7271e2824507c5aa351b97b 520 PIRSF PIRSF038958 1 513 4.3E-177 T 06-07-2017 IPR024923 Peptidoglycan biosynthesis protein, SpoVB type GTHT12_RS13510 dc42a673a7271e2824507c5aa351b97b 520 Pfam PF01943 Polysaccharide biosynthesis protein 4 306 1.3E-52 T 06-07-2017 IPR002797 Polysaccharide biosynthesis protein GO:0016020 GTHT12_RS00720 5cfff14b53f4abfc968fefec28a16336 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 06-07-2017 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00720 5cfff14b53f4abfc968fefec28a16336 179 Pfam PF00281 Ribosomal protein L5 25 80 1.6E-28 T 06-07-2017 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00720 5cfff14b53f4abfc968fefec28a16336 179 PIRSF PIRSF002161 1 179 8.1E-70 T 06-07-2017 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00720 5cfff14b53f4abfc968fefec28a16336 179 SUPERFAMILY SSF55282 3 178 7.53E-80 T 06-07-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00720 5cfff14b53f4abfc968fefec28a16336 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 46.261 T 06-07-2017 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 GTHT12_RS00720 5cfff14b53f4abfc968fefec28a16336 179 Gene3D G3DSA:3.30.1440.10 1 179 6.4E-82 T 06-07-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS00720 5cfff14b53f4abfc968fefec28a16336 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 1.8E-42 T 06-07-2017 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 GTHT12_RS18450 697b40a94ea839d9f3ba44272a68ab49 310 SUPERFAMILY SSF55831 24 246 3.93E-45 T 06-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 GTHT12_RS18450 697b40a94ea839d9f3ba44272a68ab49 310 Pfam PF00303 Thymidylate synthase 26 248 4.5E-24 T 06-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 GTHT12_RS18450 697b40a94ea839d9f3ba44272a68ab49 310 Gene3D G3DSA:3.30.572.10 19 246 2.7E-43 T 06-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 GTHT12_RS18450 697b40a94ea839d9f3ba44272a68ab49 310 PRINTS PR00108 Thymidylate synthase family signature 126 145 1.6E-7 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 GTHT12_RS18450 697b40a94ea839d9f3ba44272a68ab49 310 PRINTS PR00108 Thymidylate synthase family signature 171 197 1.6E-7 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 GTHT12_RS18450 697b40a94ea839d9f3ba44272a68ab49 310 PRINTS PR00108 Thymidylate synthase family signature 209 226 1.6E-7 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 GTHT12_RS10815 4876f93e88ee240ba4021f6add949403 133 Pfam PF04138 GtrA-like protein 14 126 7.8E-29 T 06-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 GTHT12_RS06845 684ad4d79b8e231677e1c01ed60d30ec 188 Pfam PF14154 Domain of unknown function (DUF4306) 40 125 1.5E-33 T 06-07-2017 IPR025440 Protein of unknown function DUF4306 GTHT12_RS05260 9f2a46e716657e433cb1e6cb468f3360 366 SUPERFAMILY SSF53098 237 312 4.93E-14 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS05260 9f2a46e716657e433cb1e6cb468f3360 366 SUPERFAMILY SSF53098 79 146 4.93E-14 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS05260 9f2a46e716657e433cb1e6cb468f3360 366 Pfam PF01609 Transposase DDE domain 46 300 3.3E-17 T 06-07-2017 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 GTHT12_RS08730 fdd610a5d4e698b94c1fcd7c7104408a 409 Hamap MF_01113 DNA polymerase IV [dinB]. 9 362 35.145 T 06-07-2017 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 GTHT12_RS08730 fdd610a5d4e698b94c1fcd7c7104408a 409 Gene3D G3DSA:3.30.70.270 76 172 1.7E-29 T 06-07-2017 GTHT12_RS08730 fdd610a5d4e698b94c1fcd7c7104408a 409 SUPERFAMILY SSF100879 250 346 9.03E-27 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 GTHT12_RS08730 fdd610a5d4e698b94c1fcd7c7104408a 409 SUPERFAMILY SSF56672 10 244 7.47E-77 T 06-07-2017 GTHT12_RS08730 fdd610a5d4e698b94c1fcd7c7104408a 409 Pfam PF11799 impB/mucB/samB family C-terminal domain 249 353 5.8E-19 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 GTHT12_RS08730 fdd610a5d4e698b94c1fcd7c7104408a 409 Pfam PF00817 impB/mucB/samB family 15 163 2.0E-46 T 06-07-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 GTHT12_RS08730 fdd610a5d4e698b94c1fcd7c7104408a 409 Pfam PF11798 IMS family HHH motif 177 205 1.2E-6 T 06-07-2017 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 GTHT12_RS08730 fdd610a5d4e698b94c1fcd7c7104408a 409 Gene3D G3DSA:3.30.1490.100 252 349 6.6E-28 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 GTHT12_RS08730 fdd610a5d4e698b94c1fcd7c7104408a 409 Gene3D G3DSA:1.10.150.20 174 245 1.1E-23 T 06-07-2017 GTHT12_RS01050 d455e6ce936b80ccbfbdd595a7172721 263 Gene3D G3DSA:3.90.470.20 134 230 8.1E-19 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 GTHT12_RS01050 d455e6ce936b80ccbfbdd595a7172721 263 Gene3D G3DSA:3.90.470.20 18 133 1.6E-26 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 GTHT12_RS01050 d455e6ce936b80ccbfbdd595a7172721 263 SUPERFAMILY SSF56214 18 113 2.41E-17 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 GTHT12_RS01050 d455e6ce936b80ccbfbdd595a7172721 263 SUPERFAMILY SSF56214 121 234 2.35E-19 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 GTHT12_RS01050 d455e6ce936b80ccbfbdd595a7172721 263 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 121 206 1.1E-13 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 GTHT12_RS10450 4bdcf6f660ee12a07182474fcd4e1ca1 388 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 5 386 6.8E-153 T 06-07-2017 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 GTHT12_RS06545 ef5aca66e0ec411f8f2bfb0c627eb89c 100 SUPERFAMILY SSF55315 5 99 4.91E-26 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like GTHT12_RS06545 ef5aca66e0ec411f8f2bfb0c627eb89c 100 Gene3D G3DSA:3.30.1330.30 3 98 1.7E-22 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like GTHT12_RS06545 ef5aca66e0ec411f8f2bfb0c627eb89c 100 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 6 94 5.3E-18 T 06-07-2017 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 GTHT12_RS10370 4d1dd1d6528c4ba5b9691cd2f0d629e9 508 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 446 1.4E-148 T 06-07-2017 IPR002823 Protein of unknown function DUF112, transmembrane GTHT12_RS15980 717ec8587333899e144de06cf00292f2 245 SUPERFAMILY SSF51366 5 240 1.41E-71 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 GTHT12_RS15980 717ec8587333899e144de06cf00292f2 245 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 6 237 8.4E-86 T 06-07-2017 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 GTHT12_RS15980 717ec8587333899e144de06cf00292f2 245 Pfam PF00977 Histidine biosynthesis protein 6 234 1.5E-78 T 06-07-2017 IPR006062 Histidine biosynthesis GO:0000105 GTHT12_RS15980 717ec8587333899e144de06cf00292f2 245 Gene3D G3DSA:3.20.20.70 5 241 1.4E-83 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS15980 717ec8587333899e144de06cf00292f2 245 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 5 241 37.143 T 06-07-2017 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 GTHT12_RS10525 08dd1900255040f1a54433224660015d 344 PIRSF PIRSF006470 8 344 6.8E-83 T 06-07-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 GTHT12_RS10525 08dd1900255040f1a54433224660015d 344 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 46 328 8.4E-83 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 GTHT12_RS10525 08dd1900255040f1a54433224660015d 344 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 49 292 9.9E-67 T 06-07-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 GTHT12_RS05540 71c62d0ac6014609b553e844bc7be42d 151 SUPERFAMILY SSF52833 2 141 7.35E-32 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS05540 71c62d0ac6014609b553e844bc7be42d 151 Pfam PF00578 AhpC/TSA family 6 125 5.9E-12 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 GTHT12_RS05540 71c62d0ac6014609b553e844bc7be42d 151 Gene3D G3DSA:3.40.30.10 5 149 6.2E-31 T 06-07-2017 IPR012336 Thioredoxin-like fold GTHT12_RS15520 4d2dea0ea1d65078b0e9516b8be92555 330 SUPERFAMILY SSF51261 126 316 8.89E-35 T 06-07-2017 IPR011055 Duplicated hybrid motif GTHT12_RS15520 4d2dea0ea1d65078b0e9516b8be92555 330 Gene3D G3DSA:2.70.70.10 167 317 3.0E-27 T 06-07-2017 GTHT12_RS15520 4d2dea0ea1d65078b0e9516b8be92555 330 Pfam PF01551 Peptidase family M23 205 303 1.5E-19 T 06-07-2017 IPR016047 Peptidase M23 GTHT12_RS05455 6070c04cd604cd0d9f47e23bca4d622c 75 Pfam PF08858 IDEAL domain 30 66 9.0E-15 T 06-07-2017 IPR014957 IDEAL domain GTHT12_RS05455 6070c04cd604cd0d9f47e23bca4d622c 75 SMART SM00914 30 66 8.7E-13 T 06-07-2017 IPR014957 IDEAL domain GTHT12_RS14115 efce02a7a3adc551758ce0fc5895267d 69 TIGRFAM TIGR03092 SASP_sspI: small, acid-soluble spore protein I 4 68 6.0E-36 T 06-07-2017 IPR017525 Small, acid-soluble spore protein I GO:0030436 GTHT12_RS14115 efce02a7a3adc551758ce0fc5895267d 69 Hamap MF_00669 Small, acid-soluble spore protein I [sspI]. 1 68 23.86 T 06-07-2017 IPR017525 Small, acid-soluble spore protein I GO:0030436 GTHT12_RS14115 efce02a7a3adc551758ce0fc5895267d 69 Pfam PF14098 Small, acid-soluble spore protein I 3 66 9.4E-30 T 06-07-2017 IPR017525 Small, acid-soluble spore protein I GO:0030436 GTHT12_RS07545 d9a9ca2f3c65393317e2bdf308a0f99b 323 Gene3D G3DSA:3.40.50.1980 42 167 9.5E-42 T 06-07-2017 GTHT12_RS07545 d9a9ca2f3c65393317e2bdf308a0f99b 323 SUPERFAMILY SSF53807 45 315 1.0E-69 T 06-07-2017 GTHT12_RS07545 d9a9ca2f3c65393317e2bdf308a0f99b 323 Gene3D G3DSA:3.40.50.1980 169 320 4.9E-39 T 06-07-2017 GTHT12_RS07545 d9a9ca2f3c65393317e2bdf308a0f99b 323 Pfam PF01497 Periplasmic binding protein 62 294 5.2E-36 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 GTHT12_RS18305 bae1e14e8f4929148b1228a8bbd328ec 76 Gene3D G3DSA:1.10.260.40 16 68 4.6E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS18305 bae1e14e8f4929148b1228a8bbd328ec 76 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 16 63 5.0E-7 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 GTHT12_RS18305 bae1e14e8f4929148b1228a8bbd328ec 76 SUPERFAMILY SSF47413 16 63 5.87E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS12050 2dd13da8d9bf6ed2743b34359b145996 198 Pfam PF07670 Nucleoside recognition 43 150 1.3E-9 T 06-07-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 GTHT12_RS08470 d33ebf397cda861cb2af411515515ac3 304 Pfam PF00005 ABC transporter 23 163 4.5E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS08470 d33ebf397cda861cb2af411515515ac3 304 SMART SM00382 31 212 5.9E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS08470 d33ebf397cda861cb2af411515515ac3 304 SUPERFAMILY SSF52540 5 226 1.78E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08470 d33ebf397cda861cb2af411515515ac3 304 Gene3D G3DSA:3.40.50.300 3 227 4.5E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08470 d33ebf397cda861cb2af411515515ac3 304 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 GTHT12_RS17415 614c5181ed280fb821e2271ab2a15810 497 Pfam PF00361 Proton-conducting membrane transporter 128 427 3.3E-69 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17415 614c5181ed280fb821e2271ab2a15810 497 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 10 481 8.2E-116 T 06-07-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 GTHT12_RS17415 614c5181ed280fb821e2271ab2a15810 497 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 7 483 17.296 T 06-07-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 GTHT12_RS00570 ae8e12c5117668927b98a73cf1eaf4db 170 Pfam PF05991 YacP-like NYN domain 4 167 5.2E-56 T 06-07-2017 IPR010298 Protein of unknown function DUF901 GTHT12_RS13960 0c4a0f9d17ee551cca1ce8fe766b49c8 590 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 5 570 4.6E-212 T 06-07-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 GTHT12_RS13960 0c4a0f9d17ee551cca1ce8fe766b49c8 590 Gene3D G3DSA:3.40.1440.10 15 92 3.2E-11 T 06-07-2017 IPR027299 GIY-YIG domain GTHT12_RS13960 0c4a0f9d17ee551cca1ce8fe766b49c8 590 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 372 523 2.7E-47 T 06-07-2017 IPR001162 UvrC family homology region GTHT12_RS13960 0c4a0f9d17ee551cca1ce8fe766b49c8 590 SUPERFAMILY SSF47781 502 589 2.19E-22 T 06-07-2017 IPR010994 RuvA domain 2-like GTHT12_RS13960 0c4a0f9d17ee551cca1ce8fe766b49c8 590 SMART SM00465 15 95 3.4E-24 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily GTHT12_RS13960 0c4a0f9d17ee551cca1ce8fe766b49c8 590 SUPERFAMILY SSF46600 183 235 1.57E-14 T 06-07-2017 IPR001943 UVR domain GO:0005515 GTHT12_RS13960 0c4a0f9d17ee551cca1ce8fe766b49c8 590 SUPERFAMILY SSF82771 15 96 1.07E-21 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily GTHT12_RS13960 0c4a0f9d17ee551cca1ce8fe766b49c8 590 Pfam PF02151 UvrB/uvrC motif 197 229 4.3E-10 T 06-07-2017 IPR001943 UVR domain GO:0005515 GTHT12_RS13960 0c4a0f9d17ee551cca1ce8fe766b49c8 590 Hamap MF_00203 UvrABC system protein C [uvrC]. 2 587 28.319 T 06-07-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 GTHT12_RS13960 0c4a0f9d17ee551cca1ce8fe766b49c8 590 Gene3D G3DSA:1.10.150.20 536 590 1.6E-22 T 06-07-2017 GTHT12_RS13960 0c4a0f9d17ee551cca1ce8fe766b49c8 590 Gene3D G3DSA:4.10.860.10 175 236 9.6E-18 T 06-07-2017 IPR001943 UVR domain GO:0005515 GTHT12_RS13960 0c4a0f9d17ee551cca1ce8fe766b49c8 590 Pfam PF01541 GIY-YIG catalytic domain 16 90 4.2E-11 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily GTHT12_RS16840 60606481c22339b2696561aee4513a23 441 Gene3D G3DSA:3.40.190.10 160 368 9.2E-32 T 06-07-2017 GTHT12_RS16840 60606481c22339b2696561aee4513a23 441 SUPERFAMILY SSF53850 21 440 7.44E-66 T 06-07-2017 GTHT12_RS16840 60606481c22339b2696561aee4513a23 441 Pfam PF13416 Bacterial extracellular solute-binding protein 58 377 8.6E-47 T 06-07-2017 GTHT12_RS05300 4bc371c4a782e53954aeb1c703b9cbad 126 ProDom PD020942 TRANSPOSASE C TN554 TRANSPOSON TRANSPOSITION FOR DNA-BINDING TRANSPOSABLE DNA ELEMENT 21 123 6.0E-36 T 06-07-2017 GTHT12_RS05300 4bc371c4a782e53954aeb1c703b9cbad 126 Gene3D G3DSA:1.10.357.10 16 99 5.5E-5 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 GTHT12_RS10855 fc385002c4aef55153286b2c48b2a307 501 Gene3D G3DSA:1.10.260.40 8 43 5.0E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 GTHT12_RS10855 fc385002c4aef55153286b2c48b2a307 501 Pfam PF00665 Integrase core domain 127 251 3.9E-11 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS10855 fc385002c4aef55153286b2c48b2a307 501 SUPERFAMILY SSF53098 124 285 2.23E-7 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS10855 fc385002c4aef55153286b2c48b2a307 501 Gene3D G3DSA:3.30.420.10 128 300 1.2E-6 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS03135 dbf632a67b28f131e4a05ecccb26f560 134 SUPERFAMILY SSF81324 35 126 1.44E-12 T 06-07-2017 GTHT12_RS03135 dbf632a67b28f131e4a05ecccb26f560 134 Gene3D G3DSA:1.10.287.70 35 126 4.2E-12 T 06-07-2017 GTHT12_RS03135 dbf632a67b28f131e4a05ecccb26f560 134 Pfam PF07885 Ion channel 45 126 1.1E-9 T 06-07-2017 IPR013099 Potassium channel domain GTHT12_RS07155 0e016213154367047d1fc984eca3666e 984 Pfam PF04851 Type III restriction enzyme, res subunit 10 251 9.0E-16 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 GTHT12_RS07155 0e016213154367047d1fc984eca3666e 984 SUPERFAMILY SSF52540 81 280 5.32E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07155 0e016213154367047d1fc984eca3666e 984 SUPERFAMILY SSF52540 10 29 5.32E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07155 0e016213154367047d1fc984eca3666e 984 SUPERFAMILY SSF52540 81 135 1.42E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07155 0e016213154367047d1fc984eca3666e 984 SUPERFAMILY SSF52540 481 571 1.42E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07155 0e016213154367047d1fc984eca3666e 984 Gene3D G3DSA:3.40.50.300 80 164 9.5E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS08170 7762fd8881a73e033ee4e99947a25edc 32 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 5 27 2.3E-13 T 06-07-2017 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM GTHT12_RS08170 7762fd8881a73e033ee4e99947a25edc 32 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 3 25 5.1E-13 T 06-07-2017 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM GTHT12_RS06940 c31488b2cb386b77413a105a54d83b1e 144 Pfam PF11084 Protein of unknown function (DUF2621) 4 141 1.6E-74 T 06-07-2017 IPR020203 Uncharacterised protein family, YneK GTHT12_RS06940 c31488b2cb386b77413a105a54d83b1e 144 ProDom PD086666 YNEK BH2332 20 141 7.0E-54 T 06-07-2017 IPR020203 Uncharacterised protein family, YneK GTHT12_RS06925 df0183b8e322fb1a502cacac56ed0b25 235 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 214 1.2E-65 T 06-07-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 GTHT12_RS12145 30929bb30b43ef24045dbb74e69216c5 203 Pfam PF14097 Stage V sporulation protein AE1 5 184 1.2E-82 T 06-07-2017 IPR025914 Stage V sporulation protein AE GTHT12_RS11855 109cb5218d04f998080be4a6a7688deb 76 ProDom PD059966 COTJA SPORE PROTEIN-RELATED COAT-ASSOCIATED COTJAA JA 6 68 3.0E-17 T 06-07-2017 IPR020256 Spore coat protein CotJA GTHT12_RS11855 109cb5218d04f998080be4a6a7688deb 76 Pfam PF11007 Spore coat associated protein JA (CotJA) 30 63 4.8E-11 T 06-07-2017 IPR020256 Spore coat protein CotJA GTHT12_RS05240 53599a34b64c0b27739c2bf1dc125674 335 Pfam PF00665 Integrase core domain 51 177 1.3E-26 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 GTHT12_RS05240 53599a34b64c0b27739c2bf1dc125674 335 SUPERFAMILY SSF53098 50 221 7.21E-22 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS05240 53599a34b64c0b27739c2bf1dc125674 335 Gene3D G3DSA:3.30.420.10 52 214 7.9E-19 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 GTHT12_RS01325 68eea934f56ac97f08df101ce38b45cd 116 Gene3D G3DSA:2.30.30.110 2 113 9.3E-49 T 06-07-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor GTHT12_RS01325 68eea934f56ac97f08df101ce38b45cd 116 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 111 9.5E-34 T 06-07-2017 IPR003477 mRNA interferase PemK-like protein GO:0003677 GTHT12_RS01325 68eea934f56ac97f08df101ce38b45cd 116 SUPERFAMILY SSF50118 2 113 2.29E-42 T 06-07-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor GTHT12_RS01325 68eea934f56ac97f08df101ce38b45cd 116 PIRSF PIRSF033490 1 113 6.5E-40 T 06-07-2017 IPR003477 mRNA interferase PemK-like protein GO:0003677 GTHT12_RS11845 499228ea0532490a4922b114162b18e6 267 Pfam PF00149 Calcineurin-like phosphoesterase 44 197 9.3E-10 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 GTHT12_RS11845 499228ea0532490a4922b114162b18e6 267 Gene3D G3DSA:3.60.21.10 61 203 4.6E-19 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like GTHT12_RS11845 499228ea0532490a4922b114162b18e6 267 SUPERFAMILY SSF56300 41 254 1.7E-30 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like GTHT12_RS05750 5bf13ce8a005fd246fe51cb3eab53418 77 Pfam PF14003 YlbE-like protein 13 73 2.5E-25 T 06-07-2017 IPR025613 YlbE-like protein GTHT12_RS12300 8e9c9cd5e325c234c4a3ec76b4b4c23d 306 Hamap MF_01818 Ribonuclease BN [rbn]. 1 304 41.899 T 06-07-2017 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 GTHT12_RS12300 8e9c9cd5e325c234c4a3ec76b4b4c23d 306 SUPERFAMILY SSF56281 2 303 2.54E-84 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS12300 8e9c9cd5e325c234c4a3ec76b4b4c23d 306 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 2 304 6.3E-116 T 06-07-2017 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 GTHT12_RS12300 8e9c9cd5e325c234c4a3ec76b4b4c23d 306 Gene3D G3DSA:3.60.15.10 4 305 2.0E-87 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS12300 8e9c9cd5e325c234c4a3ec76b4b4c23d 306 Pfam PF12706 Beta-lactamase superfamily domain 202 270 1.9E-9 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS12300 8e9c9cd5e325c234c4a3ec76b4b4c23d 306 Pfam PF00753 Metallo-beta-lactamase superfamily 26 107 1.0E-9 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS11965 00fe828d282869b99d34496e1b91d20c 323 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 4 303 2.4E-82 T 06-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 GTHT12_RS11965 00fe828d282869b99d34496e1b91d20c 323 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 320 107.189 T 06-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 GTHT12_RS11965 00fe828d282869b99d34496e1b91d20c 323 Pfam PF03186 CobD/Cbib protein 7 292 1.8E-109 T 06-07-2017 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 GTHT12_RS18565 a576fec69eb9c16ddaae08745aa4593d 115 Pfam PF08863 YolD-like protein 16 109 1.4E-24 T 06-07-2017 IPR014962 YolD-like protein GTHT12_RS04395 8fbaaf96ac210ebcc8a49b8b3c6950ad 212 Pfam PF04607 Region found in RelA / SpoT proteins 44 162 1.6E-38 T 06-07-2017 IPR007685 RelA/SpoT GO:0015969 GTHT12_RS04395 8fbaaf96ac210ebcc8a49b8b3c6950ad 212 SMART SM00954 44 165 3.4E-43 T 06-07-2017 IPR007685 RelA/SpoT GO:0015969 GTHT12_RS04395 8fbaaf96ac210ebcc8a49b8b3c6950ad 212 Gene3D G3DSA:3.30.460.10 7 145 2.9E-40 T 06-07-2017 GTHT12_RS04395 8fbaaf96ac210ebcc8a49b8b3c6950ad 212 SUPERFAMILY SSF81301 5 198 1.23E-60 T 06-07-2017 GTHT12_RS04395 8fbaaf96ac210ebcc8a49b8b3c6950ad 212 Gene3D G3DSA:1.10.287.860 148 202 1.2E-25 T 06-07-2017 GTHT12_RS09900 d8d0dd74fc30d40495105a9aadbd1dd1 208 Gene3D G3DSA:3.20.20.370 6 203 5.0E-64 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 GTHT12_RS09900 d8d0dd74fc30d40495105a9aadbd1dd1 208 Pfam PF01522 Polysaccharide deacetylase 11 132 1.9E-35 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 GTHT12_RS09900 d8d0dd74fc30d40495105a9aadbd1dd1 208 SUPERFAMILY SSF88713 7 203 4.45E-60 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 GTHT12_RS12385 4403a4eaed6003efde3108cf89f50560 145 Pfam PF06491 Disulphide isomerase 10 142 1.4E-58 T 06-07-2017 IPR009474 Putative bacilliredoxin, YphP/YqiW family GTHT12_RS12385 4403a4eaed6003efde3108cf89f50560 145 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 10 142 1.0E-59 T 06-07-2017 IPR009474 Putative bacilliredoxin, YphP/YqiW family GTHT12_RS13355 520b370304e044692f60e11f6d5f9513 217 Pfam PF01596 O-methyltransferase 42 212 8.5E-32 T 06-07-2017 IPR002935 O-methyltransferase, family 3 GO:0008171 GTHT12_RS13355 520b370304e044692f60e11f6d5f9513 217 Gene3D G3DSA:3.40.50.150 4 213 1.4E-58 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS13355 520b370304e044692f60e11f6d5f9513 217 SUPERFAMILY SSF53335 4 210 6.15E-42 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS09360 c0a5b7e3d7bc525a164c2ba517139222 145 Pfam PF06491 Disulphide isomerase 8 144 1.7E-62 T 06-07-2017 IPR009474 Putative bacilliredoxin, YphP/YqiW family GTHT12_RS09360 c0a5b7e3d7bc525a164c2ba517139222 145 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 8 144 7.6E-64 T 06-07-2017 IPR009474 Putative bacilliredoxin, YphP/YqiW family GTHT12_RS18180 6c078f880a086c370d3768dec838c090 65 PIRSF PIRSF037263 1 65 8.0E-34 T 06-07-2017 IPR009296 Protein of unknown function DUF951 GTHT12_RS18180 6c078f880a086c370d3768dec838c090 65 Pfam PF06107 Bacterial protein of unknown function (DUF951) 8 60 5.0E-29 T 06-07-2017 IPR009296 Protein of unknown function DUF951 GTHT12_RS14965 de8148cfe56befdbee639f89fe52ca54 209 Pfam PF01810 LysE type translocator 17 205 5.1E-37 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 GTHT12_RS14965 de8148cfe56befdbee639f89fe52ca54 209 PIRSF PIRSF006324 2 209 1.1E-57 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 GTHT12_RS11400 54170d0ecbc6decf2309e5a5e6aa8b6c 260 Pfam PF12787 EcsC protein family 9 249 1.3E-80 T 06-07-2017 IPR024787 EcsC protein GTHT12_RS11400 54170d0ecbc6decf2309e5a5e6aa8b6c 260 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 8 252 1.0E-112 T 06-07-2017 GTHT12_RS16605 42eeef141bc5234e13872a03e1613130 146 Pfam PF14101 Domain of unknown function (DUF4275) 1 143 1.6E-60 T 06-07-2017 IPR025454 Protein of unknown function DUF4275 GTHT12_RS18345 1e4995d8c15e0d4ba3f3d7d17deab402 617 Gene3D G3DSA:3.40.50.300 224 319 5.6E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18345 1e4995d8c15e0d4ba3f3d7d17deab402 617 Gene3D G3DSA:3.40.50.300 423 570 5.6E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18345 1e4995d8c15e0d4ba3f3d7d17deab402 617 SUPERFAMILY SSF52540 201 559 4.07E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS18345 1e4995d8c15e0d4ba3f3d7d17deab402 617 Pfam PF01935 Domain of unknown function DUF87 238 405 2.4E-7 T 06-07-2017 IPR002789 Helicase HerA, central domain GTHT12_RS01960 7fab55636ba5591bad5c008bfed98e2c 623 PIRSF PIRSF018968 1 621 2.5E-133 T 06-07-2017 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 GTHT12_RS01960 7fab55636ba5591bad5c008bfed98e2c 623 Pfam PF02687 FtsX-like permease family 62 174 1.4E-13 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 GTHT12_RS04755 2b8991f3a508304b2d1dc2f85a2a507b 139 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 93 108 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 GTHT12_RS04755 2b8991f3a508304b2d1dc2f85a2a507b 139 PRINTS PR00069 Aldo-keto reductase signature 23 52 3.8E-20 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GTHT12_RS04755 2b8991f3a508304b2d1dc2f85a2a507b 139 PRINTS PR00069 Aldo-keto reductase signature 60 84 3.8E-20 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 GTHT12_RS04755 2b8991f3a508304b2d1dc2f85a2a507b 139 Pfam PF00248 Aldo/keto reductase family 1 125 1.8E-21 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain GTHT12_RS04755 2b8991f3a508304b2d1dc2f85a2a507b 139 SUPERFAMILY SSF51430 1 134 2.1E-46 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain GTHT12_RS04755 2b8991f3a508304b2d1dc2f85a2a507b 139 Gene3D G3DSA:3.20.20.100 1 136 1.1E-54 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain GTHT12_RS03760 41b9e1ee5c5ff5d121af118e47333654 428 ProSitePatterns PS00161 Isocitrate lyase signature. 186 191 - T 06-07-2017 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 GTHT12_RS03760 41b9e1ee5c5ff5d121af118e47333654 428 SUPERFAMILY SSF51621 6 425 6.73E-163 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GTHT12_RS03760 41b9e1ee5c5ff5d121af118e47333654 428 Pfam PF00463 Isocitrate lyase family 250 425 3.0E-49 T 06-07-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 GTHT12_RS03760 41b9e1ee5c5ff5d121af118e47333654 428 Pfam PF00463 Isocitrate lyase family 13 249 6.5E-62 T 06-07-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 GTHT12_RS03760 41b9e1ee5c5ff5d121af118e47333654 428 PIRSF PIRSF001362 1 428 3.6E-245 T 06-07-2017 GTHT12_RS03760 41b9e1ee5c5ff5d121af118e47333654 428 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 9 248 2.2E-108 T 06-07-2017 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 GTHT12_RS03760 41b9e1ee5c5ff5d121af118e47333654 428 Gene3D G3DSA:3.20.20.60 5 408 5.1E-170 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 GTHT12_RS15630 1e7f4e32e3d9011923e40e7c08fa6c90 115 SUPERFAMILY SSF55718 54 110 1.65E-5 T 06-07-2017 IPR003033 SCP2 sterol-binding domain GTHT12_RS04980 caeeeb2e3dc58001c2465c4a55176932 299 SUPERFAMILY SSF161098 59 288 1.57E-62 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS04980 caeeeb2e3dc58001c2465c4a55176932 299 Gene3D G3DSA:1.10.3720.10 66 296 2.9E-66 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS04980 caeeeb2e3dc58001c2465c4a55176932 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 294 2.2E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS03905 eeb116bfc32d99db06028e377b164406 426 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 209 411 3.0E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS03905 eeb116bfc32d99db06028e377b164406 426 Gene3D G3DSA:1.20.58.370 124 159 4.4E-9 T 06-07-2017 GTHT12_RS03905 eeb116bfc32d99db06028e377b164406 426 SUPERFAMILY SSF161098 174 407 2.35E-56 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS03905 eeb116bfc32d99db06028e377b164406 426 Gene3D G3DSA:1.10.3720.10 188 419 3.8E-62 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS03905 eeb116bfc32d99db06028e377b164406 426 SUPERFAMILY SSF160964 72 177 5.62E-11 T 06-07-2017 GTHT12_RS09245 def90928abff937239f285b901c304de 210 PIRSF PIRSF020606 2 205 3.0E-66 T 06-07-2017 IPR014509 Uncharacterised conserved protein UCP020606 GTHT12_RS09245 def90928abff937239f285b901c304de 210 Pfam PF09997 Predicted membrane protein (DUF2238) 42 182 1.9E-52 T 06-07-2017 IPR014509 Uncharacterised conserved protein UCP020606 GTHT12_RS00980 f8cdee3a3e878f2fbde1da3242c191a2 360 Gene3D G3DSA:3.20.20.70 60 344 6.7E-18 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS00980 f8cdee3a3e878f2fbde1da3242c191a2 360 Pfam PF04055 Radical SAM superfamily 67 183 2.1E-7 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 GTHT12_RS00980 f8cdee3a3e878f2fbde1da3242c191a2 360 SUPERFAMILY SSF102114 59 335 8.37E-19 T 06-07-2017 GTHT12_RS16690 650b8aefd1d3e2d9c9979ab1fba9fe32 114 Pfam PF12986 Domain of unknown function (DUF3870) 8 100 4.8E-38 T 06-07-2017 IPR024617 Domain of unknown function DUF3870 GTHT12_RS05320 ed6a2f85f25403a4eb4831445e370e1a 214 ProSitePatterns PS00414 Profilin signature. 1 9 - T 06-07-2017 IPR027310 Profilin conserved site GO:0003779 Reactome: R-HSA-376176|Reactome: R-HSA-5663220 GTHT12_RS01705 263b94a6dd11508d9cdbdaa5b8edfe89 257 SUPERFAMILY SSF54593 3 224 8.96E-14 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GTHT12_RS01705 263b94a6dd11508d9cdbdaa5b8edfe89 257 Gene3D G3DSA:3.10.180.10 4 127 9.9E-7 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GTHT12_RS01705 263b94a6dd11508d9cdbdaa5b8edfe89 257 Gene3D G3DSA:3.10.180.10 171 226 1.0E-4 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GTHT12_RS01705 263b94a6dd11508d9cdbdaa5b8edfe89 257 Pfam PF13468 Glyoxalase-like domain 5 192 1.1E-39 T 06-07-2017 IPR025870 Glyoxalase-like domain GTHT12_RS07605 5e3f556f0eddf38d4e49e904065170d9 84 SMART SM00899 7 80 2.2E-20 T 06-07-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 GTHT12_RS07605 5e3f556f0eddf38d4e49e904065170d9 84 Pfam PF04023 FeoA domain 9 77 1.5E-17 T 06-07-2017 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 GTHT12_RS07605 5e3f556f0eddf38d4e49e904065170d9 84 SUPERFAMILY SSF50037 10 81 3.89E-18 T 06-07-2017 IPR008988 Transcriptional repressor, C-terminal GTHT12_RS14295 b12c78bcc2e716b8d0eb091bd9501a7e 102 Pfam PF14007 YtpI-like protein 5 90 3.9E-37 T 06-07-2017 IPR025618 YtpI-like protein GTHT12_RS15380 934e78daa24dfc774a85e22f4e1dcbe4 332 Pfam PF01384 Phosphate transporter family 22 162 1.5E-39 T 06-07-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 GTHT12_RS15380 934e78daa24dfc774a85e22f4e1dcbe4 332 Pfam PF01384 Phosphate transporter family 170 321 8.7E-48 T 06-07-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 GTHT12_RS04205 0a8580404966914ca01801624e7bec6c 410 Gene3D G3DSA:3.60.70.12 17 283 1.3E-103 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 GTHT12_RS04205 0a8580404966914ca01801624e7bec6c 410 Pfam PF01960 ArgJ family 26 410 1.8E-151 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 GTHT12_RS04205 0a8580404966914ca01801624e7bec6c 410 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 37 410 0.0 T 06-07-2017 GTHT12_RS04205 0a8580404966914ca01801624e7bec6c 410 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 410 150.669 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 GTHT12_RS04205 0a8580404966914ca01801624e7bec6c 410 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 16 410 3.3E-163 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 GTHT12_RS04205 0a8580404966914ca01801624e7bec6c 410 SUPERFAMILY SSF56266 20 406 1.28E-140 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 GTHT12_RS01690 f5df2e584d2923981a735adcecf21998 407 PIRSF PIRSF012509 20 407 7.8E-163 T 06-07-2017 IPR011426 CamS sex pheromone cAM373 GTHT12_RS01690 f5df2e584d2923981a735adcecf21998 407 Pfam PF07537 CamS sex pheromone cAM373 precursor 76 397 8.4E-128 T 06-07-2017 IPR011426 CamS sex pheromone cAM373 GTHT12_RS01690 f5df2e584d2923981a735adcecf21998 407 Gene3D G3DSA:3.10.570.10 73 406 4.5E-138 T 06-07-2017 GTHT12_RS10520 ab0464e20fdb08ce6031593fd1dbabfa 195 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 24 151 6.0E-29 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component GTHT12_RS09555 19336d14cb1b8b9cb4f0453812f965dd 167 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 5 151 9.6E-31 T 06-07-2017 IPR007404 LexA-binding, inner membrane-associated putative hydrolase GTHT12_RS05040 a69172c93b614d9eb4946f0fef7dcfbe 391 Gene3D G3DSA:3.40.640.10 49 261 1.6E-59 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 GTHT12_RS05040 a69172c93b614d9eb4946f0fef7dcfbe 391 Pfam PF00155 Aminotransferase class I and II 35 385 3.3E-65 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 GTHT12_RS05040 a69172c93b614d9eb4946f0fef7dcfbe 391 SUPERFAMILY SSF53383 6 388 1.93E-106 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase GTHT12_RS05040 a69172c93b614d9eb4946f0fef7dcfbe 391 Gene3D G3DSA:3.90.1150.10 262 388 1.1E-39 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 GTHT12_RS08595 175e763bc700695f554a9f2337f6c556 309 Pfam PF02628 Cytochrome oxidase assembly protein 47 278 2.1E-29 T 06-07-2017 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 GTHT12_RS08595 175e763bc700695f554a9f2337f6c556 309 Pfam PF02628 Cytochrome oxidase assembly protein 4 45 4.7E-7 T 06-07-2017 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 GTHT12_RS04795 69622a61b24116a252b14b65f553c34e 101 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 70 81 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site GTHT12_RS04795 69622a61b24116a252b14b65f553c34e 101 Gene3D G3DSA:3.30.70.20 32 91 7.4E-9 T 06-07-2017 GTHT12_RS04795 69622a61b24116a252b14b65f553c34e 101 SUPERFAMILY SSF54862 29 99 2.48E-17 T 06-07-2017 GTHT12_RS04795 69622a61b24116a252b14b65f553c34e 101 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 22 96 6.7E-11 T 06-07-2017 IPR007859 ETF-QO/FixX GO:0051536|GO:0055114 Reactome: R-HSA-611105 GTHT12_RS04795 69622a61b24116a252b14b65f553c34e 101 PIRSF PIRSF036548 7 101 6.5E-22 T 06-07-2017 IPR012206 Ferredoxin-like, FixX GO:0005506 GTHT12_RS06695 fcd23a52b2320fa172af0733433d703d 263 Pfam PF11868 Protein of unknown function (DUF3388) 72 261 1.1E-104 T 06-07-2017 IPR024514 Domain of unknown function DUF3388 GTHT12_RS06695 fcd23a52b2320fa172af0733433d703d 263 PIRSF PIRSF021288 1 262 2.2E-141 T 06-07-2017 IPR016784 Uncharacterised protein UCP021288 with ACT domain GTHT12_RS06695 fcd23a52b2320fa172af0733433d703d 263 Gene3D G3DSA:3.30.70.260 12 74 1.0E-5 T 06-07-2017 GTHT12_RS06695 fcd23a52b2320fa172af0733433d703d 263 SUPERFAMILY SSF55021 5 75 7.08E-10 T 06-07-2017 GTHT12_RS17300 8f0455f4b25e79a20253f462514a3636 312 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 82 225 2.9E-52 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain GTHT12_RS17300 8f0455f4b25e79a20253f462514a3636 312 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 83 224 1.9E-50 T 06-07-2017 IPR004474 Cell envelope-related transcriptional attenuator domain GTHT12_RS09780 de0400ff9de44ce627840d9720626525 133 SUPERFAMILY SSF54637 1 129 1.57E-39 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS09780 de0400ff9de44ce627840d9720626525 133 Pfam PF03061 Thioesterase superfamily 17 92 8.7E-10 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 GTHT12_RS09780 de0400ff9de44ce627840d9720626525 133 Gene3D G3DSA:3.10.129.10 1 128 4.5E-40 T 06-07-2017 IPR029069 HotDog domain GTHT12_RS03745 9080386678aecaf53b001aedcc1aae86 238 Pfam PF03591 AzlC protein 23 158 1.5E-40 T 06-07-2017 IPR011606 Branched-chain amino acid transport, permease GTHT12_RS06320 1ea9fc71576ebf2a9d4595db394572fa 150 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 150 5.9E-50 T 06-07-2017 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 GTHT12_RS06320 1ea9fc71576ebf2a9d4595db394572fa 150 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 104 147 5.4E-10 T 06-07-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain GTHT12_RS06320 1ea9fc71576ebf2a9d4595db394572fa 150 Pfam PF00460 Flagella basal body rod protein 7 36 1.3E-11 T 06-07-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 GTHT12_RS06320 1ea9fc71576ebf2a9d4595db394572fa 150 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 06-07-2017 IPR019776 Flagellar basal body rod protein, conserved site GTHT12_RS04780 7da24674d8b6c7eb2935f77943c4e342 271 PIRSF PIRSF000090 2 268 1.5E-86 T 06-07-2017 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105 GTHT12_RS04780 7da24674d8b6c7eb2935f77943c4e342 271 Gene3D G3DSA:3.40.50.620 3 265 8.4E-87 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold GTHT12_RS04780 7da24674d8b6c7eb2935f77943c4e342 271 SMART SM00893 23 219 1.8E-57 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 GTHT12_RS04780 7da24674d8b6c7eb2935f77943c4e342 271 Pfam PF01012 Electron transfer flavoprotein domain 24 202 3.3E-45 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 GTHT12_RS04780 7da24674d8b6c7eb2935f77943c4e342 271 SUPERFAMILY SSF52402 2 260 1.08E-71 T 06-07-2017 GTHT12_RS09675 681778ac73c62e5969d02dcc1d9c1d69 622 Gene3D G3DSA:2.60.40.420 501 618 1.5E-42 T 06-07-2017 IPR008972 Cupredoxin GTHT12_RS09675 681778ac73c62e5969d02dcc1d9c1d69 622 SUPERFAMILY SSF50974 44 491 1.57E-90 T 06-07-2017 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 GTHT12_RS09675 681778ac73c62e5969d02dcc1d9c1d69 622 SUPERFAMILY SSF49503 505 620 6.84E-27 T 06-07-2017 IPR008972 Cupredoxin GTHT12_RS09675 681778ac73c62e5969d02dcc1d9c1d69 622 Pfam PF13473 Cupredoxin-like domain 538 614 5.7E-10 T 06-07-2017 IPR028096 EfeO-type cupredoxin-like domain GTHT12_RS09675 681778ac73c62e5969d02dcc1d9c1d69 622 TIGRFAM TIGR04246 nitrous_NosZ_Gp: nitrous-oxide reductase, Sec-dependent 41 620 1.9E-282 T 06-07-2017 IPR026468 Nitrous-oxide reductase, Sec-dependent GTHT12_RS09675 681778ac73c62e5969d02dcc1d9c1d69 622 Gene3D G3DSA:2.130.10.10 102 500 3.6E-114 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 GTHT12_RS17355 d0b11457752388bb97daa31f8f7f25db 169 ProDom PD076312 INHIBITOR INTRACELLULAR PROTEINASE PRECURSOR SIGNAL DOMAIN SLH S-LAYER PROTEASE BSUPI 75 149 3.0E-33 T 06-07-2017 IPR020481 Intracellular proteinase inhibitor BsuPI GTHT12_RS17355 d0b11457752388bb97daa31f8f7f25db 169 Pfam PF12690 Intracellular proteinase inhibitor 74 147 1.1E-22 T 06-07-2017 IPR020481 Intracellular proteinase inhibitor BsuPI GTHT12_RS10160 8d0c39484f880d1235f952d5b858f45b 80 SUPERFAMILY SSF52096 3 62 4.21E-7 T 06-07-2017 IPR029045 ClpP/crotonase-like domain GTHT12_RS10160 8d0c39484f880d1235f952d5b858f45b 80 Gene3D G3DSA:1.10.12.10 5 56 1.7E-9 T 06-07-2017 IPR014748 Crontonase, C-terminal GTHT12_RS03840 0fc238b262653643360898d8e8888bb8 74 Pfam PF10676 Spore germination protein gerPA/gerPF 1 73 3.8E-25 T 06-07-2017 IPR019618 Spore germination protein GerPA/GerPF GTHT12_RS07635 c9ef5b3cdf974ba8cd38962f26a9fe06 262 Pfam PF06182 ABC-2 family transporter protein 38 261 1.4E-53 T 06-07-2017 IPR010390 Protein of unknown function DUF990 GTHT12_RS03910 c3a86f959ea69ea173a6aef902d2ab5e 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 272 3.1E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS03910 c3a86f959ea69ea173a6aef902d2ab5e 280 Gene3D G3DSA:1.10.3720.10 2 267 8.2E-72 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS03910 c3a86f959ea69ea173a6aef902d2ab5e 280 SUPERFAMILY SSF161098 9 280 6.17E-74 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS10165 dab8a0fddf0ce20762dc7a7fcfc6d718 276 PIRSF PIRSF006625 1 276 3.0E-141 T 06-07-2017 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 GTHT12_RS10165 dab8a0fddf0ce20762dc7a7fcfc6d718 276 Gene3D G3DSA:2.60.120.500 131 276 6.1E-76 T 06-07-2017 IPR027447 5-keto-4-deoxyuronate isomerase, C-terminal domain KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 GTHT12_RS10165 dab8a0fddf0ce20762dc7a7fcfc6d718 276 Gene3D G3DSA:2.60.120.520 20 130 1.0E-54 T 06-07-2017 IPR027449 5-keto-4-deoxyuronate isomerase, N-terminal domain KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 GTHT12_RS10165 dab8a0fddf0ce20762dc7a7fcfc6d718 276 Hamap MF_00687 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [kduI]. 1 276 57.762 T 06-07-2017 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 GTHT12_RS10165 dab8a0fddf0ce20762dc7a7fcfc6d718 276 SUPERFAMILY SSF51182 1 260 2.19E-115 T 06-07-2017 IPR011051 RmlC-like cupin domain GTHT12_RS10165 dab8a0fddf0ce20762dc7a7fcfc6d718 276 Pfam PF04962 KduI/IolB family 40 271 1.2E-38 T 06-07-2017 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 GTHT12_RS17260 119928cf7ba7b6ddf94abaff9b9ef271 450 SUPERFAMILY SSF52540 152 288 3.43E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17260 119928cf7ba7b6ddf94abaff9b9ef271 450 Pfam PF02223 Thymidylate kinase 243 430 1.5E-7 T 06-07-2017 GTHT12_RS17260 119928cf7ba7b6ddf94abaff9b9ef271 450 SUPERFAMILY SSF52540 235 283 2.2E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17260 119928cf7ba7b6ddf94abaff9b9ef271 450 SUPERFAMILY SSF52540 310 446 2.2E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS17260 119928cf7ba7b6ddf94abaff9b9ef271 450 Gene3D G3DSA:3.40.50.300 238 438 2.5E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS10440 789fbe681afb39702ddd67248e4066ec 218 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 8 208 2.2E-57 T 06-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 GTHT12_RS10440 789fbe681afb39702ddd67248e4066ec 218 Pfam PF01081 KDPG and KHG aldolase 8 196 7.9E-45 T 06-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 GTHT12_RS10440 789fbe681afb39702ddd67248e4066ec 218 Gene3D G3DSA:3.20.20.70 7 213 1.4E-73 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS10440 789fbe681afb39702ddd67248e4066ec 218 SUPERFAMILY SSF51569 4 209 1.81E-63 T 06-07-2017 GTHT12_RS15050 8699fb116abe5f6615a602be1b52acb3 290 Pfam PF00872 Transposase, Mutator family 16 288 7.4E-108 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS10140 cbdeae7d16868902d061ff7b05bfd6fe 308 Gene3D G3DSA:1.10.3720.10 85 298 2.9E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS10140 cbdeae7d16868902d061ff7b05bfd6fe 308 SUPERFAMILY SSF161098 88 285 3.27E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS10140 cbdeae7d16868902d061ff7b05bfd6fe 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 302 5.1E-40 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS18860 db25eac115fb4889b51e325b12a2961c 292 Pfam PF13612 Transposase DDE domain 111 267 4.3E-29 T 06-07-2017 IPR025668 Transposase DDE domain GTHT12_RS14385 273f4160976129d225b55dac50d52689 209 Pfam PF11167 Protein of unknown function (DUF2953) 112 165 3.0E-17 T 06-07-2017 IPR021338 Protein of unknown function DUF2953 GTHT12_RS06230 08a155d7992a8e76efe9e6d00ba12dde 128 Pfam PF11068 YlqD protein 1 128 4.0E-37 T 06-07-2017 IPR021297 YlqD protein GTHT12_RS02645 0c54f0f930f4ae83964f9d22222c345f 926 TIGRFAM TIGR03929 T7_esaA_Nterm: type VII secretion protein EsaA 10 200 1.1E-76 T 06-07-2017 IPR023838 Type VII secretion system EsaA GO:0016021 GTHT12_RS02645 0c54f0f930f4ae83964f9d22222c345f 926 Pfam PF12698 ABC-2 family transporter protein 13 191 2.3E-9 T 06-07-2017 GTHT12_RS17790 2117563708f720ad66f414e166c5a6a4 300 PIRSF PIRSF005355 9 299 2.3E-59 T 06-07-2017 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 GTHT12_RS17790 2117563708f720ad66f414e166c5a6a4 300 Pfam PF01040 UbiA prenyltransferase family 32 280 5.9E-31 T 06-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 GTHT12_RS16185 bd6de49d713086fd71906c94f4873c03 522 Pfam PF13751 Transposase DDE domain 382 506 1.3E-30 T 06-07-2017 IPR025668 Transposase DDE domain GTHT12_RS16185 bd6de49d713086fd71906c94f4873c03 522 Pfam PF05598 Transposase domain (DUF772) 49 117 1.6E-22 T 06-07-2017 IPR008490 Transposase InsH, N-terminal GTHT12_RS03075 bd6de49d713086fd71906c94f4873c03 522 Pfam PF13751 Transposase DDE domain 382 506 1.3E-30 T 06-07-2017 IPR025668 Transposase DDE domain GTHT12_RS03075 bd6de49d713086fd71906c94f4873c03 522 Pfam PF05598 Transposase domain (DUF772) 49 117 1.6E-22 T 06-07-2017 IPR008490 Transposase InsH, N-terminal GTHT12_RS06325 ae803c26560ecad1cb8f213a6268f6a4 98 Pfam PF02049 Flagellar hook-basal body complex protein FliE 19 97 1.0E-30 T 06-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 GTHT12_RS06325 ae803c26560ecad1cb8f213a6268f6a4 98 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 3 98 18.12 T 06-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 GTHT12_RS06325 ae803c26560ecad1cb8f213a6268f6a4 98 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 62 78 1.3E-17 T 06-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 GTHT12_RS06325 ae803c26560ecad1cb8f213a6268f6a4 98 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 83 96 1.3E-17 T 06-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 GTHT12_RS06325 ae803c26560ecad1cb8f213a6268f6a4 98 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 28 44 1.3E-17 T 06-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 GTHT12_RS06325 ae803c26560ecad1cb8f213a6268f6a4 98 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 18 96 1.0E-26 T 06-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 GTHT12_RS16375 1c41223c20850314523e7d88289f43db 415 SUPERFAMILY SSF53756 173 408 1.07E-17 T 06-07-2017 GTHT12_RS16375 1c41223c20850314523e7d88289f43db 415 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 38 409 9.6E-132 T 06-07-2017 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 GTHT12_RS04435 cd7a8d40e1f86caa4e924a58cd754797 379 Pfam PF00534 Glycosyl transferases group 1 183 355 9.0E-43 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 GTHT12_RS04435 cd7a8d40e1f86caa4e924a58cd754797 379 Gene3D G3DSA:3.40.50.2000 155 355 4.2E-31 T 06-07-2017 GTHT12_RS04435 cd7a8d40e1f86caa4e924a58cd754797 379 SUPERFAMILY SSF53756 2 375 8.97E-70 T 06-07-2017 GTHT12_RS04435 cd7a8d40e1f86caa4e924a58cd754797 379 Pfam PF13439 Glycosyltransferase Family 4 18 166 1.9E-11 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 GTHT12_RS12320 2988ff999e87a0be445fe1d86b6b8714 479 Gene3D G3DSA:3.40.605.10 9 266 1.5E-87 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS12320 2988ff999e87a0be445fe1d86b6b8714 479 Gene3D G3DSA:3.40.309.10 267 449 1.7E-64 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 GTHT12_RS12320 2988ff999e87a0be445fe1d86b6b8714 479 Pfam PF00171 Aldehyde dehydrogenase family 16 473 1.1E-163 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 GTHT12_RS12320 2988ff999e87a0be445fe1d86b6b8714 479 SUPERFAMILY SSF53720 5 476 2.09E-148 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 GTHT12_RS04915 a8b246ec5e62e96d7f9b86f823e09676 141 Pfam PF12821 Threonine/Serine exporter, ThrE 5 132 1.3E-37 T 06-07-2017 IPR024528 Threonine/Serine exporter, ThrE GTHT12_RS14120 54ecdd4d7732221565e50e8457bf85fe 35 Pfam PF12323 Helix-turn-helix domain 4 34 4.7E-7 T 06-07-2017 IPR021027 Transposase, putative, helix-turn-helix domain GTHT12_RS03100 7ce37b7c851f47db537fe511986e359b 361 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 118 141 - T 06-07-2017 IPR017441 Protein kinase, ATP binding site GO:0005524 GTHT12_RS03100 7ce37b7c851f47db537fe511986e359b 361 Pfam PF00069 Protein kinase domain 114 350 4.2E-33 T 06-07-2017 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 GTHT12_RS03100 7ce37b7c851f47db537fe511986e359b 361 Gene3D G3DSA:3.30.200.20 115 215 2.7E-20 T 06-07-2017 GTHT12_RS03100 7ce37b7c851f47db537fe511986e359b 361 Gene3D G3DSA:1.10.510.10 216 347 1.4E-16 T 06-07-2017 GTHT12_RS03100 7ce37b7c851f47db537fe511986e359b 361 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 227 239 - T 06-07-2017 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 GTHT12_RS03100 7ce37b7c851f47db537fe511986e359b 361 SUPERFAMILY SSF56112 115 349 3.51E-41 T 06-07-2017 IPR011009 Protein kinase-like domain GTHT12_RS02895 bdeeede021b6bceffe4f863fde3c168e 42 Pfam PF14152 YfhE-like protein 3 38 8.8E-21 T 06-07-2017 IPR025437 YfhE-like protein GTHT12_RS14645 035c3a76eb45c6d068c093ed78b90c2c 176 SUPERFAMILY SSF52972 2 165 2.96E-48 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like GTHT12_RS14645 035c3a76eb45c6d068c093ed78b90c2c 176 Pfam PF01931 Protein of unknown function DUF84 7 159 1.0E-45 T 06-07-2017 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 GTHT12_RS14645 035c3a76eb45c6d068c093ed78b90c2c 176 Hamap MF_00648 Non-canonical purine NTP phosphatase. 2 168 26.732 T 06-07-2017 IPR002786 Non-canonical purine NTP phosphatase GTHT12_RS14645 035c3a76eb45c6d068c093ed78b90c2c 176 Gene3D G3DSA:3.90.950.10 2 165 8.7E-50 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like GTHT12_RS17700 d898560e9a977bdb0415ebedc671d78c 291 PIRSF PIRSF036979 1 291 9.6E-99 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 GTHT12_RS17700 d898560e9a977bdb0415ebedc671d78c 291 SUPERFAMILY SSF52768 12 289 2.7E-86 T 06-07-2017 GTHT12_RS17700 d898560e9a977bdb0415ebedc671d78c 291 Gene3D G3DSA:3.40.800.10 16 290 7.7E-87 T 06-07-2017 IPR023696 Ureohydrolase domain GTHT12_RS17700 d898560e9a977bdb0415ebedc671d78c 291 TIGRFAM TIGR01230 agmatinase: agmatinase 11 286 1.0E-115 T 06-07-2017 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 GTHT12_RS17700 d898560e9a977bdb0415ebedc671d78c 291 ProSitePatterns PS01053 Arginase family signature. 214 235 - T 06-07-2017 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 GTHT12_RS17700 d898560e9a977bdb0415ebedc671d78c 291 Pfam PF00491 Arginase family 23 285 1.6E-80 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 GTHT12_RS12780 c0ec950ce2517fa7be2766a687643958 342 Pfam PF00482 Type II secretion system (T2SS), protein F 213 334 2.5E-18 T 06-07-2017 IPR018076 Type II secretion system F domain GTHT12_RS12780 c0ec950ce2517fa7be2766a687643958 342 Pfam PF00482 Type II secretion system (T2SS), protein F 14 128 4.3E-11 T 06-07-2017 IPR018076 Type II secretion system F domain GTHT12_RS08685 026a21dcec3601a5eda5dd0720ef98c2 105 Pfam PF02583 Metal-sensitive transcriptional repressor 24 101 2.9E-30 T 06-07-2017 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 GTHT12_RS11070 12e9c3bf8871b44f143bd4d09c0a90b1 189 Pfam PF00583 Acetyltransferase (GNAT) family 47 125 2.9E-5 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS11070 12e9c3bf8871b44f143bd4d09c0a90b1 189 Gene3D G3DSA:3.40.630.30 12 132 2.1E-10 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS11070 12e9c3bf8871b44f143bd4d09c0a90b1 189 SUPERFAMILY SSF55729 7 162 3.6E-16 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS09775 93770a2771cd318131b692bc4934afc3 71 Pfam PF13076 Fur-regulated basic protein A 12 46 6.3E-13 T 06-07-2017 IPR025072 Fur-regulated basic protein A GTHT12_RS04420 b59bae13e6a4a72c2d5bffbe8dc11492 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 254 1.9E-86 T 06-07-2017 GTHT12_RS04420 b59bae13e6a4a72c2d5bffbe8dc11492 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS04420 b59bae13e6a4a72c2d5bffbe8dc11492 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS04420 b59bae13e6a4a72c2d5bffbe8dc11492 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS04420 b59bae13e6a4a72c2d5bffbe8dc11492 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR GTHT12_RS04420 b59bae13e6a4a72c2d5bffbe8dc11492 258 Gene3D G3DSA:3.40.50.720 2 255 3.7E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS04420 b59bae13e6a4a72c2d5bffbe8dc11492 258 PIRSF PIRSF000094 2 258 1.5E-104 T 06-07-2017 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 GTHT12_RS04420 b59bae13e6a4a72c2d5bffbe8dc11492 258 SUPERFAMILY SSF51735 6 256 1.79E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS02160 2d3bc4ea395aeb53d1bba35a7e7d0496 86 Pfam PF06414 Zeta toxin 1 69 2.0E-5 T 06-07-2017 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 GTHT12_RS06780 32796ddc4b8996d6e0561cb9f0924701 506 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 50 496 5.9E-172 T 06-07-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 GTHT12_RS06780 32796ddc4b8996d6e0561cb9f0924701 506 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 7 496 5.3E-199 T 06-07-2017 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 GTHT12_RS18640 1f38f41de797bb36aee57f0fed64c93d 255 Gene3D G3DSA:3.60.15.10 1 220 1.0E-39 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS18640 1f38f41de797bb36aee57f0fed64c93d 255 SMART SM00849 7 198 3.6E-10 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS18640 1f38f41de797bb36aee57f0fed64c93d 255 SUPERFAMILY SSF56281 1 202 7.21E-32 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS18640 1f38f41de797bb36aee57f0fed64c93d 255 Pfam PF12706 Beta-lactamase superfamily domain 19 198 4.9E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase GTHT12_RS18695 13eeb0060b998b8e41f944583a82130e 315 Gene3D G3DSA:1.10.3720.10 27 302 2.5E-39 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS18695 13eeb0060b998b8e41f944583a82130e 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 308 3.3E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS18695 13eeb0060b998b8e41f944583a82130e 315 SUPERFAMILY SSF161098 71 299 6.54E-46 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS06145 bf06a91446cc58901ca9f6cfe35add14 120 Pfam PF03780 Asp23 family, cell envelope-related function 9 116 9.8E-37 T 06-07-2017 IPR005531 Alkaline shock protein Asp23 GTHT12_RS17875 11546a98b0fb421221dea6ead854e6bd 271 SUPERFAMILY SSF53613 1 264 4.05E-77 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS17875 11546a98b0fb421221dea6ead854e6bd 271 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 262 1.0E-84 T 06-07-2017 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 GTHT12_RS17875 11546a98b0fb421221dea6ead854e6bd 271 Pfam PF08543 Phosphomethylpyrimidine kinase 13 261 9.6E-90 T 06-07-2017 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 GTHT12_RS17875 11546a98b0fb421221dea6ead854e6bd 271 Gene3D G3DSA:3.40.1190.20 3 262 2.7E-92 T 06-07-2017 IPR029056 Ribokinase-like GTHT12_RS16265 f0cf72a3699299044ea0168a361a9ee6 98 Gene3D G3DSA:3.40.1690.10 19 95 3.4E-22 T 06-07-2017 IPR029025 Type III secretion system substrate exporter, C-terminal GTHT12_RS16265 f0cf72a3699299044ea0168a361a9ee6 98 Pfam PF01312 FlhB HrpN YscU SpaS Family 19 90 5.6E-18 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 GTHT12_RS16265 f0cf72a3699299044ea0168a361a9ee6 98 SUPERFAMILY SSF160544 17 95 3.4E-22 T 06-07-2017 IPR029025 Type III secretion system substrate exporter, C-terminal GTHT12_RS16705 3ed11722ee0bfc8bbff454d08254da4a 335 Pfam PF00877 NlpC/P60 family 224 331 3.7E-27 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain GTHT12_RS16705 3ed11722ee0bfc8bbff454d08254da4a 335 SUPERFAMILY SSF54001 208 333 1.5E-43 T 06-07-2017 GTHT12_RS16705 3ed11722ee0bfc8bbff454d08254da4a 335 Gene3D G3DSA:3.90.1720.10 209 333 5.5E-46 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain GTHT12_RS09680 d7feede4814b8751b3a32d93e9ff676b 151 Gene3D G3DSA:1.10.760.10 70 146 3.3E-8 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GTHT12_RS09680 d7feede4814b8751b3a32d93e9ff676b 151 SUPERFAMILY SSF46626 64 149 2.01E-10 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 GTHT12_RS12295 cc826091f409c4e8f5130675d4ff4ebc 340 Hamap MF_01614 NADPH dehydrogenase [namA]. 2 338 69.085 T 06-07-2017 IPR023663 NADPH dehydrogenase GO:0003959|GO:0055114 GTHT12_RS12295 cc826091f409c4e8f5130675d4ff4ebc 340 SUPERFAMILY SSF51395 3 334 2.59E-116 T 06-07-2017 GTHT12_RS12295 cc826091f409c4e8f5130675d4ff4ebc 340 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 323 4.8E-85 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 GTHT12_RS12295 cc826091f409c4e8f5130675d4ff4ebc 340 Gene3D G3DSA:3.20.20.70 3 334 4.1E-126 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS09345 04cc5f920a491fe8f0a365755587ad9c 194 Pfam PF14005 YpjP-like protein 61 192 5.8E-59 T 06-07-2017 IPR025616 YpjP-like protein GTHT12_RS12030 5de310c3b98aa49bdac15b6034d411b1 552 Pfam PF05140 ResB-like family 64 429 2.4E-74 T 06-07-2017 IPR007816 ResB-like domain GTHT12_RS12030 5de310c3b98aa49bdac15b6034d411b1 552 Pfam PF05140 ResB-like family 441 520 4.7E-17 T 06-07-2017 IPR007816 ResB-like domain GTHT12_RS10965 1284429083e19264209e4567e58fce31 86 Pfam PF02583 Metal-sensitive transcriptional repressor 4 82 5.3E-24 T 06-07-2017 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 GTHT12_RS02765 81c3aa625eecb95ddd775de6d167fced 130 Pfam PF07508 Recombinase 52 120 1.0E-10 T 06-07-2017 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 GTHT12_RS04390 e1e9f80e7c36956e128df03291085d19 125 Hamap MF_01861 UPF0738 protein . 3 123 27.096 T 06-07-2017 IPR020908 Uncharacterised protein family UPF0738 GTHT12_RS09140 34c3cee4e6b1e34b6cceba359a92fa12 470 Pfam PF03553 Na+/H+ antiporter family 156 439 1.5E-35 T 06-07-2017 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 GTHT12_RS02635 c07deb57d4e6a01a8bb2145b9c669798 428 Pfam PF10140 WXG100 protein secretion system (Wss), protein YukC 26 380 9.7E-126 T 06-07-2017 IPR018778 Type VII secretion system EssB GTHT12_RS02635 c07deb57d4e6a01a8bb2145b9c669798 428 TIGRFAM TIGR03926 T7_EssB: type VII secretion protein EssB 7 380 7.0E-152 T 06-07-2017 IPR018778 Type VII secretion system EssB GTHT12_RS12570 f58ff20eaee383153e636a15c977cf08 203 Pfam PF09581 Stage III sporulation protein AF (Spore_III_AF) 12 198 3.0E-37 T 06-07-2017 IPR014245 Sporulation stage III, protein AF GTHT12_RS12570 f58ff20eaee383153e636a15c977cf08 203 TIGRFAM TIGR02896 spore_III_AF: stage III sporulation protein AF 2 114 3.2E-36 T 06-07-2017 IPR014245 Sporulation stage III, protein AF GTHT12_RS01500 aee463053411938bce889c336dc303e9 164 Gene3D G3DSA:3.30.70.1450 85 159 1.3E-20 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 GTHT12_RS01500 aee463053411938bce889c336dc303e9 164 PIRSF PIRSF005028 1 163 3.0E-55 T 06-07-2017 IPR026278 Potassium/proton antiporter subunit KhtT GTHT12_RS01500 aee463053411938bce889c336dc303e9 164 Pfam PF02080 TrkA-C domain 90 157 9.2E-17 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 GTHT12_RS01500 aee463053411938bce889c336dc303e9 164 SUPERFAMILY SSF116726 72 158 1.31E-18 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 GTHT12_RS04055 e798ef1ea93923bdf9e3b79d4c274dc7 79 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 6 74 2.5E-19 T 06-07-2017 IPR018720 Domain of unknown function DUF2249 GTHT12_RS16770 3f266bfdb8a2874a54643f81fd459fcd 428 Gene3D G3DSA:3.10.450.50 2 23 2.5E-8 T 06-07-2017 IPR032710 NTF2-like domain GTHT12_RS16770 3f266bfdb8a2874a54643f81fd459fcd 428 SUPERFAMILY SSF103642 3 24 1.96E-7 T 06-07-2017 GTHT12_RS16770 3f266bfdb8a2874a54643f81fd459fcd 428 Pfam PF02810 SEC-C motif 5 23 1.4E-9 T 06-07-2017 IPR004027 SEC-C motif GTHT12_RS05225 0d2935fdc1b522742ed9beb291b21dd2 136 Pfam PF11457 Protein of unknown function (DUF3021) 7 133 4.2E-30 T 06-07-2017 IPR021560 Protein of unknown function DUF3021 GTHT12_RS13350 85819f4414ee3a45278e55f416ee9553 309 Pfam PF01136 Peptidase family U32 75 306 2.1E-66 T 06-07-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 GTHT12_RS13350 85819f4414ee3a45278e55f416ee9553 309 SUPERFAMILY SSF102114 13 95 2.94E-5 T 06-07-2017 GTHT12_RS13350 85819f4414ee3a45278e55f416ee9553 309 Gene3D G3DSA:3.20.20.70 12 97 8.5E-5 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS13350 85819f4414ee3a45278e55f416ee9553 309 Gene3D G3DSA:3.20.20.70 130 165 8.5E-5 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS17085 00bc5e03570661001fa8af72bf3cb272 332 SUPERFAMILY SSF101478 44 329 1.26E-68 T 06-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 GTHT12_RS17085 00bc5e03570661001fa8af72bf3cb272 332 Pfam PF03747 ADP-ribosylglycohydrolase 51 308 4.0E-58 T 06-07-2017 IPR005502 ADP-ribosylation/Crystallin J1 GTHT12_RS05480 19dd8b7cf5c4d6dde907b318ca170935 289 Pfam PF00149 Calcineurin-like phosphoesterase 64 227 4.6E-11 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 GTHT12_RS05480 19dd8b7cf5c4d6dde907b318ca170935 289 SUPERFAMILY SSF56300 60 286 2.53E-36 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like GTHT12_RS05480 19dd8b7cf5c4d6dde907b318ca170935 289 Gene3D G3DSA:3.60.21.10 63 253 1.5E-24 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like GTHT12_RS18080 11d7b27de5387bd11b405c11f53b484e 292 Pfam PF13612 Transposase DDE domain 111 267 3.8E-27 T 06-07-2017 IPR025668 Transposase DDE domain GTHT12_RS03835 c507b2713e2b26677503ce75075c1c67 74 Pfam PF10676 Spore germination protein gerPA/gerPF 1 73 1.5E-27 T 06-07-2017 IPR019618 Spore germination protein GerPA/GerPF GTHT12_RS13550 dfc6e2e48477643a293aeae83644bde1 160 Pfam PF08955 BofC C-terminal domain 81 154 5.9E-33 T 06-07-2017 IPR015050 Bypass of forespore C, C-terminal GTHT12_RS13550 dfc6e2e48477643a293aeae83644bde1 160 Pfam PF08977 Bypass of Forespore C, N terminal 29 79 1.6E-23 T 06-07-2017 IPR015071 Bypass-of-forespore C, N-terminal GTHT12_RS01460 1703e2f2ea389c133837988836cee98e 50 Pfam PF02416 mttA/Hcf106 family 3 47 3.7E-20 T 06-07-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 GTHT12_RS01460 1703e2f2ea389c133837988836cee98e 50 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 42 4.3E-19 T 06-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 GTHT12_RS01460 1703e2f2ea389c133837988836cee98e 50 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 4 49 15.917 T 06-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 GTHT12_RS01120 d86c54b29d96521b40e7537167de6ff0 92 SUPERFAMILY SSF52218 2 80 7.91E-8 T 06-07-2017 IPR029039 Flavoprotein-like domain GTHT12_RS01120 d86c54b29d96521b40e7537167de6ff0 92 Gene3D G3DSA:3.40.50.360 1 85 7.3E-14 T 06-07-2017 IPR029039 Flavoprotein-like domain GTHT12_RS01120 d86c54b29d96521b40e7537167de6ff0 92 Pfam PF03358 NADPH-dependent FMN reductase 2 48 4.8E-6 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 GTHT12_RS10770 d859fdd2e067803bd154c51622624db2 106 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 5 104 4.0E-34 T 06-07-2017 IPR009799 EthD domain GTHT12_RS10770 d859fdd2e067803bd154c51622624db2 106 Gene3D G3DSA:3.30.70.900 2 104 3.6E-34 T 06-07-2017 GTHT12_RS10770 d859fdd2e067803bd154c51622624db2 106 Pfam PF07110 EthD domain 16 91 6.4E-12 T 06-07-2017 IPR009799 EthD domain GTHT12_RS10770 d859fdd2e067803bd154c51622624db2 106 SUPERFAMILY SSF54909 4 103 2.53E-26 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel GTHT12_RS13240 226728335689c06b25d8b040ee12a217 46 SUPERFAMILY SSF100985 1 45 1.83E-18 T 06-07-2017 IPR015064 Sporulation inhibitor A GTHT12_RS13240 226728335689c06b25d8b040ee12a217 46 Pfam PF08970 Sporulation inhibitor A 1 44 1.7E-24 T 06-07-2017 IPR015064 Sporulation inhibitor A GTHT12_RS01660 4256b9aaa34314574aebee9a6d403596 339 Gene3D G3DSA:3.50.90.10 37 337 2.9E-108 T 06-07-2017 IPR023158 YerB-like domain GTHT12_RS01660 4256b9aaa34314574aebee9a6d403596 339 Pfam PF11258 Protein of unknown function (DUF3048) 53 327 4.5E-86 T 06-07-2017 IPR021416 Protein of unknown function DUF3048 GTHT12_RS01660 4256b9aaa34314574aebee9a6d403596 339 SUPERFAMILY SSF159774 50 337 1.01E-98 T 06-07-2017 IPR023158 YerB-like domain GTHT12_RS14130 78589b8c8435d435c9fadbe57bca0f50 161 SUPERFAMILY SSF101386 3 161 1.87E-40 T 06-07-2017 GTHT12_RS14130 78589b8c8435d435c9fadbe57bca0f50 161 PIRSF PIRSF030140 1 161 1.3E-54 T 06-07-2017 IPR016947 Uncharacterised phage-associated protein UCP030140 GTHT12_RS14130 78589b8c8435d435c9fadbe57bca0f50 161 Pfam PF08761 dUTPase 3 161 4.3E-47 T 06-07-2017 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 GTHT12_RS14170 d40e713c414fc019f020e19f2cc366b1 463 Pfam PF07261 Replication initiation and membrane attachment 334 395 7.3E-11 T 06-07-2017 IPR006343 Replication protein, DnaD/DnaB domain GTHT12_RS14170 d40e713c414fc019f020e19f2cc366b1 463 Gene3D G3DSA:1.10.10.630 355 393 7.1E-4 T 06-07-2017 IPR006343 Replication protein, DnaD/DnaB domain GTHT12_RS13315 5e7e4edb046e643653ce17241d89abc7 69 Pfam PF10750 Protein of unknown function (DUF2536) 3 68 7.6E-36 T 06-07-2017 IPR019686 Protein of unknown function DUF2536 GTHT12_RS14530 22fbf96fb4116970d41e9e48c6aaaf1c 138 Pfam PF00872 Transposase, Mutator family 10 138 1.6E-37 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS08715 ba389672155d3ec6f373f032b45d1e70 160 Pfam PF03703 Bacterial PH domain 73 147 8.7E-19 T 06-07-2017 IPR005182 Domain of unknown function DUF304 GTHT12_RS05605 5367a050b8167e524e0e144746511385 41 Pfam PF13790 SR1 protein 1 32 1.8E-18 T 06-07-2017 IPR025236 SR1 protein GTHT12_RS18885 2dbb552bc77f47083011bab6182fc010 77 Gene3D G3DSA:1.10.443.10 6 75 5.9E-17 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS18885 2dbb552bc77f47083011bab6182fc010 77 Pfam PF00589 Phage integrase family 16 63 5.7E-12 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS18885 2dbb552bc77f47083011bab6182fc010 77 SUPERFAMILY SSF56349 7 74 1.71E-15 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 GTHT12_RS07085 a9c5427752f2bfb41dcd25c016141be1 442 Pfam PF07670 Nucleoside recognition 131 231 2.3E-9 T 06-07-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 GTHT12_RS18720 3508bd9a39ef523c2fc949d1ca6fe9c8 304 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 3 84 1.2E-12 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 GTHT12_RS18720 3508bd9a39ef523c2fc949d1ca6fe9c8 304 Gene3D G3DSA:1.10.443.10 110 298 6.2E-40 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS18720 3508bd9a39ef523c2fc949d1ca6fe9c8 304 Gene3D G3DSA:1.10.150.130 3 94 2.4E-17 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal GTHT12_RS18720 3508bd9a39ef523c2fc949d1ca6fe9c8 304 Pfam PF00589 Phage integrase family 110 290 3.2E-30 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS18720 3508bd9a39ef523c2fc949d1ca6fe9c8 304 SUPERFAMILY SSF56349 3 298 1.35E-48 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 GTHT12_RS07785 bff14ccf784ac1e31dce282854c94751 59 ProDom PD052450 H SPORE ACID-SOLUBLE SMALL SASP SPORULATION SMALL PROTEIN-RELATED SOLUBLE RBL04815 1 58 2.0E-21 T 06-07-2017 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 GTHT12_RS07785 bff14ccf784ac1e31dce282854c94751 59 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 1 58 1.4E-26 T 06-07-2017 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 GTHT12_RS07785 bff14ccf784ac1e31dce282854c94751 59 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 59 19.252 T 06-07-2017 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 GTHT12_RS07785 bff14ccf784ac1e31dce282854c94751 59 Pfam PF08141 Small acid-soluble spore protein H family 1 58 3.3E-21 T 06-07-2017 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 GTHT12_RS02220 936c0d917af37eb8957c9b09401ddd6f 371 Gene3D G3DSA:1.50.10.10 167 302 2.0E-8 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 GTHT12_RS02220 936c0d917af37eb8957c9b09401ddd6f 371 SUPERFAMILY SSF48208 169 342 3.57E-14 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 GTHT12_RS01650 0a5c8ac414d9d9c5fd8136e41b1570e7 81 Pfam PF11127 Protein of unknown function (DUF2892) 1 66 4.1E-12 T 06-07-2017 IPR021309 Protein of unknown function DUF2892 GTHT12_RS04455 2aefdf7f62d8e3464991ea620217ef0e 318 Gene3D G3DSA:3.40.50.720 1 306 8.9E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS04455 2aefdf7f62d8e3464991ea620217ef0e 318 SUPERFAMILY SSF51735 1 315 6.44E-87 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS04455 2aefdf7f62d8e3464991ea620217ef0e 318 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 242 9.6E-58 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 GTHT12_RS13560 1ffb51aa2ced4b0581f303af02a490f6 244 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 14 230 1.1E-35 T 06-07-2017 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like GTHT12_RS17265 9b6c6d59ed235269b0dd6725e732f167 376 Gene3D G3DSA:3.40.50.2000 189 342 3.8E-17 T 06-07-2017 GTHT12_RS17265 9b6c6d59ed235269b0dd6725e732f167 376 SUPERFAMILY SSF53756 13 372 2.36E-56 T 06-07-2017 GTHT12_RS17265 9b6c6d59ed235269b0dd6725e732f167 376 Pfam PF13439 Glycosyltransferase Family 4 15 179 6.5E-19 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 GTHT12_RS17265 9b6c6d59ed235269b0dd6725e732f167 376 Pfam PF00534 Glycosyl transferases group 1 185 350 5.0E-26 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 GTHT12_RS11725 76b5254a3869172293edd8c39a19b57e 67 Pfam PF10966 Protein of unknown function (DUF2768) 7 64 3.1E-24 T 06-07-2017 IPR020076 Protein of unknown function DUF2768 GTHT12_RS11725 76b5254a3869172293edd8c39a19b57e 67 ProDom PD054986 YPHE TRANSMEMBRANE MEMBRANE PRECURSOR BH1643 SIGNAL 1 67 7.0E-26 T 06-07-2017 IPR020076 Protein of unknown function DUF2768 GTHT12_RS11440 c4b141b0e4be541df3654bb7e33009e4 84 ProDom PD059965 SASP SPORULATION-SPECIFIC SIGMA-G-DEPENDENT SPORULATION SPECIFIC CSGA 1 84 2.0E-40 T 06-07-2017 IPR020255 Sigma-G-dependent sporulation-specific SASP protein GTHT12_RS11260 1b3705882b0913975c9ca144ddba6f35 371 Pfam PF04443 Acyl-protein synthetase, LuxE 27 361 2.5E-25 T 06-07-2017 IPR007534 Acyl-protein synthetase, LuxE GO:0008218|GO:0047474 MetaCyc: PWY-7723 GTHT12_RS11260 1b3705882b0913975c9ca144ddba6f35 371 SUPERFAMILY SSF56801 80 347 2.18E-5 T 06-07-2017 GTHT12_RS07430 3eb8fcaf5e16714561d14dcfdc61344b 697 Pfam PF14345 GDYXXLXY protein 552 693 2.7E-35 T 06-07-2017 IPR025833 GDYXXLXY protein GTHT12_RS07430 3eb8fcaf5e16714561d14dcfdc61344b 697 Pfam PF09925 Predicted membrane protein (DUF2157) 10 113 7.1E-17 T 06-07-2017 IPR018677 Domain of unknown function DUF2157 GTHT12_RS02195 8727cd2b8fed5b49c86c72af6923e29e 827 Pfam PF12704 MacB-like periplasmic core domain 19 208 1.0E-9 T 06-07-2017 IPR025857 MacB-like periplasmic core domain GTHT12_RS02195 8727cd2b8fed5b49c86c72af6923e29e 827 Pfam PF02687 FtsX-like permease family 244 364 5.6E-15 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 GTHT12_RS02195 8727cd2b8fed5b49c86c72af6923e29e 827 Pfam PF02687 FtsX-like permease family 703 817 1.6E-16 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 GTHT12_RS02410 9d2721ac0e17483e93749732946e604c 123 Pfam PF09350 Domain of unknown function (DUF1992) 7 74 2.3E-23 T 06-07-2017 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain GTHT12_RS17210 8bfae97e5d4874b48b9032fe24749048 323 SUPERFAMILY SSF51735 2 321 3.38E-102 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS17210 8bfae97e5d4874b48b9032fe24749048 323 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 251 2.1E-60 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 GTHT12_RS17210 8bfae97e5d4874b48b9032fe24749048 323 Gene3D G3DSA:3.90.25.10 253 322 7.5E-49 T 06-07-2017 GTHT12_RS17210 8bfae97e5d4874b48b9032fe24749048 323 Gene3D G3DSA:3.90.25.10 169 220 7.5E-49 T 06-07-2017 GTHT12_RS17210 8bfae97e5d4874b48b9032fe24749048 323 Gene3D G3DSA:3.40.50.720 2 168 1.3E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS17210 8bfae97e5d4874b48b9032fe24749048 323 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 1 322 1.0E-137 T 06-07-2017 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 GTHT12_RS03035 5b26a01c2893efa94b677f5184a4e50f 346 Pfam PF12762 ISXO2-like transposase domain 154 308 4.2E-17 T 06-07-2017 IPR024445 ISXO2-like transposase domain GTHT12_RS03035 5b26a01c2893efa94b677f5184a4e50f 346 SMART SM01126 153 311 1.3E-34 T 06-07-2017 IPR024445 ISXO2-like transposase domain GTHT12_RS14280 daf62d1e4590e82dbcd1e046eeab8df8 113 Pfam PF14034 Sporulation protein YtrH 11 108 1.7E-38 T 06-07-2017 IPR025689 Sporulation protein YtrH GTHT12_RS02335 6255c6861dd5401d9bb90fec6a88798a 149 Pfam PF09021 HutP 9 147 1.5E-40 T 06-07-2017 IPR015111 Hut operon regulatory protein HutP GTHT12_RS02335 6255c6861dd5401d9bb90fec6a88798a 149 Hamap MF_00779 Hut operon positive regulatory protein [hutP]. 1 149 39.552 T 06-07-2017 IPR023552 Hut operon regulatory protein HutP, bacillales GTHT12_RS02335 6255c6861dd5401d9bb90fec6a88798a 149 SUPERFAMILY SSF111064 8 149 2.48E-59 T 06-07-2017 IPR015111 Hut operon regulatory protein HutP GTHT12_RS02335 6255c6861dd5401d9bb90fec6a88798a 149 Gene3D G3DSA:3.40.1510.10 4 149 3.0E-60 T 06-07-2017 IPR015111 Hut operon regulatory protein HutP GTHT12_RS09355 79b171648a456fb1ce9dafeca305aacf 43 Pfam PF14115 YuzL-like protein 3 41 1.9E-18 T 06-07-2017 IPR025625 YuzL-like protein GTHT12_RS04505 00e83bc7d08ed7c0ad72f6c9974710a8 68 Pfam PF07870 Protein of unknown function (DUF1657) 7 55 1.1E-21 T 06-07-2017 IPR012452 Protein of unknown function DUF1657 GTHT12_RS02930 bd7511c1d978621bd28c45f1aa89ff2d 326 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 2 176 8.1E-27 T 06-07-2017 IPR007404 LexA-binding, inner membrane-associated putative hydrolase GTHT12_RS06890 ece43a4adc79715e292db098ef5242c0 76 SUPERFAMILY SSF158221 1 42 1.96E-13 T 06-07-2017 GTHT12_RS06890 ece43a4adc79715e292db098ef5242c0 76 Pfam PF05979 Bacterial protein of unknown function (DUF896) 6 68 2.2E-30 T 06-07-2017 IPR009242 Protein of unknown function DUF896 GTHT12_RS06890 ece43a4adc79715e292db098ef5242c0 76 Gene3D G3DSA:1.10.287.540 1 60 1.2E-28 T 06-07-2017 IPR023218 UPF0291 structural domain GTHT12_RS06890 ece43a4adc79715e292db098ef5242c0 76 Hamap MF_01103 UPF0291 protein . 2 60 15.123 T 06-07-2017 IPR009242 Protein of unknown function DUF896 GTHT12_RS05180 3f867507ae5245568e67f2c8ef3a72cf 228 SUPERFAMILY SSF51735 8 216 2.97E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS05180 3f867507ae5245568e67f2c8ef3a72cf 228 Pfam PF13460 NAD(P)H-binding 19 134 1.5E-9 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS05180 3f867507ae5245568e67f2c8ef3a72cf 228 Gene3D G3DSA:3.40.50.720 12 226 3.9E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain GTHT12_RS06365 87242986da6362a4f5d152afeb5a2b9d 142 Pfam PF03963 Flagellar hook capping protein - N-terminal region 14 75 5.1E-21 T 06-07-2017 IPR005648 Flagellar hook capping protein GTHT12_RS07840 c85834692eed743ae513e46e5c8a56b4 212 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 16 207 3.5E-32 T 06-07-2017 GTHT12_RS05060 b901627bd121b34991d339f710e63d0d 180 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 176 29.191 T 06-07-2017 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.53+1.13.11.54|MetaCyc: PWY-4361|MetaCyc: PWY-5389 GTHT12_RS05060 b901627bd121b34991d339f710e63d0d 180 Gene3D G3DSA:2.60.120.10 10 175 1.1E-46 T 06-07-2017 IPR014710 RmlC-like jelly roll fold GTHT12_RS05060 b901627bd121b34991d339f710e63d0d 180 SUPERFAMILY SSF51182 13 174 2.2E-30 T 06-07-2017 IPR011051 RmlC-like cupin domain GTHT12_RS05060 b901627bd121b34991d339f710e63d0d 180 Pfam PF03079 ARD/ARD' family 16 169 1.0E-32 T 06-07-2017 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 GTHT12_RS08985 88f0b62178441c4dd28806bd7794408a 170 Gene3D G3DSA:3.40.630.30 1 163 3.6E-54 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS08985 88f0b62178441c4dd28806bd7794408a 170 SUPERFAMILY SSF55729 1 151 5.31E-45 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS08985 88f0b62178441c4dd28806bd7794408a 170 Pfam PF13302 Acetyltransferase (GNAT) domain 8 147 4.0E-39 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS03975 1da2c95a38262d504d776d99447e1a75 268 Gene3D G3DSA:1.10.3720.10 3 258 1.1E-44 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS03975 1da2c95a38262d504d776d99447e1a75 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 257 1.2E-5 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS03975 1da2c95a38262d504d776d99447e1a75 268 SUPERFAMILY SSF161098 3 258 4.86E-50 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS04665 0cf386310e6fe4826f77fa13f99a55bc 166 Pfam PF00872 Transposase, Mutator family 13 165 4.0E-42 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS18560 26dd8774e016922b56901b5439e957db 171 Pfam PF11799 impB/mucB/samB family C-terminal domain 11 115 1.8E-16 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 GTHT12_RS18560 26dd8774e016922b56901b5439e957db 171 SUPERFAMILY SSF100879 11 109 5.3E-20 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 GTHT12_RS18560 26dd8774e016922b56901b5439e957db 171 Gene3D G3DSA:3.30.1490.100 12 118 1.4E-18 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 GTHT12_RS16020 3f49e71a44ee5d22628934c5a6830751 312 Pfam PF07670 Nucleoside recognition 19 98 6.1E-7 T 06-07-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 GTHT12_RS16020 3f49e71a44ee5d22628934c5a6830751 312 Pfam PF07670 Nucleoside recognition 175 263 4.4E-6 T 06-07-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 GTHT12_RS00255 4aec3a116e7b81d372f06365c7458f6d 124 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 2 122 3.0E-56 T 06-07-2017 IPR006056 RidA family GTHT12_RS00255 4aec3a116e7b81d372f06365c7458f6d 124 Gene3D G3DSA:3.30.1330.40 3 122 1.9E-52 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like GTHT12_RS00255 4aec3a116e7b81d372f06365c7458f6d 124 Pfam PF01042 Endoribonuclease L-PSP 6 122 2.2E-48 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family GTHT12_RS00255 4aec3a116e7b81d372f06365c7458f6d 124 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 99 117 - T 06-07-2017 IPR019897 RidA, conserved site GTHT12_RS00255 4aec3a116e7b81d372f06365c7458f6d 124 SUPERFAMILY SSF55298 4 124 1.19E-49 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like GTHT12_RS06160 0cea7eb499f059432584a56d6a0f2f0f 293 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 290 1.4E-137 T 06-07-2017 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 GTHT12_RS06160 0cea7eb499f059432584a56d6a0f2f0f 293 Pfam PF03313 Serine dehydratase alpha chain 15 274 1.8E-76 T 06-07-2017 IPR005130 Serine dehydratase-like, alpha subunit GTHT12_RS10075 ad9e2f43c77206d27389963f0ac6e343 318 Pfam PF13407 Periplasmic binding protein domain 39 289 1.9E-61 T 06-07-2017 IPR025997 Periplasmic binding protein GTHT12_RS10075 ad9e2f43c77206d27389963f0ac6e343 318 Gene3D G3DSA:3.40.50.2300 154 299 1.3E-51 T 06-07-2017 GTHT12_RS10075 ad9e2f43c77206d27389963f0ac6e343 318 SUPERFAMILY SSF53822 38 308 1.24E-74 T 06-07-2017 IPR028082 Periplasmic binding protein-like I GTHT12_RS10075 ad9e2f43c77206d27389963f0ac6e343 318 Gene3D G3DSA:3.40.50.2300 38 153 8.3E-33 T 06-07-2017 GTHT12_RS01825 ddccebee4dfc02cb5097cec2e79c4df5 437 Pfam PF02447 GntP family permease 5 387 3.1E-8 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 GTHT12_RS18660 954641fe33a4c56e0ead726e886f702b 49 Pfam PF12841 YvrJ protein family 6 39 7.5E-17 T 06-07-2017 IPR024419 Protein of unknown function YvrJ GTHT12_RS15725 b8b507a7c2086c2694a239cfc80c2bc4 187 Gene3D G3DSA:3.50.50.60 1 174 4.2E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS15725 b8b507a7c2086c2694a239cfc80c2bc4 187 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 107 1.4E-10 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS15725 b8b507a7c2086c2694a239cfc80c2bc4 187 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 53 63 6.0E-12 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS15725 b8b507a7c2086c2694a239cfc80c2bc4 187 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 98 106 6.0E-12 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS15725 b8b507a7c2086c2694a239cfc80c2bc4 187 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 6.0E-12 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 GTHT12_RS15725 b8b507a7c2086c2694a239cfc80c2bc4 187 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.4E-7 T 06-07-2017 GTHT12_RS15725 b8b507a7c2086c2694a239cfc80c2bc4 187 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 2.4E-7 T 06-07-2017 GTHT12_RS15725 b8b507a7c2086c2694a239cfc80c2bc4 187 SUPERFAMILY SSF51905 1 174 3.21E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 GTHT12_RS04605 6f1aca270aba5f1d83f8aeb325914232 351 Pfam PF04230 Polysaccharide pyruvyl transferase 14 283 3.4E-33 T 06-07-2017 IPR007345 Polysaccharide pyruvyl transferase GTHT12_RS04605 6f1aca270aba5f1d83f8aeb325914232 351 SUPERFAMILY SSF52317 1 93 1.23E-5 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like GTHT12_RS05805 f044bab9fd25acb747bbb59ae4f18cfc 180 Pfam PF02620 Uncharacterized ACR, COG1399 56 173 2.4E-22 T 06-07-2017 IPR003772 Protein of unknown function DUF177 GTHT12_RS16430 fc964febc8a05eea96cb613a004b2d05 146 Pfam PF14183 YwpF-like protein 2 130 5.7E-47 T 06-07-2017 IPR025573 YwpF-like protein GTHT12_RS12565 92079ccc02ab6802e3e8ef9da2624089 212 TIGRFAM TIGR02830 spore_III_AG: stage III sporulation protein AG 27 212 1.6E-70 T 06-07-2017 IPR014195 Sporulation stage III, protein AG GTHT12_RS10775 bed78b74e81a822147295ba63ee8a1e3 160 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 13 154 2.4E-53 T 06-07-2017 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit GTHT12_RS10775 bed78b74e81a822147295ba63ee8a1e3 160 SUPERFAMILY SSF117916 2 95 4.14E-26 T 06-07-2017 GTHT12_RS10775 bed78b74e81a822147295ba63ee8a1e3 160 Pfam PF01883 Domain of unknown function DUF59 4 75 1.2E-17 T 06-07-2017 IPR002744 Domain of unknown function DUF59 GTHT12_RS05885 7c3b6847a30a56dda19d63ac60a99165 261 Pfam PF08478 POTRA domain, FtsQ-type 51 117 4.9E-21 T 06-07-2017 IPR013685 Polypeptide-transport-associated, FtsQ-type GTHT12_RS05885 7c3b6847a30a56dda19d63ac60a99165 261 Pfam PF03799 Cell division protein FtsQ 122 236 6.0E-8 T 06-07-2017 IPR005548 Cell division protein FtsQ/DivIB GTHT12_RS05885 7c3b6847a30a56dda19d63ac60a99165 261 Hamap MF_00912 Cell division protein DivIB [divIB]. 9 253 30.699 T 06-07-2017 IPR026580 Cell division protein DivIB GTHT12_RS16520 8d9cac2bfd3f8ff40a8d13bcafbebb67 368 Pfam PF03595 Voltage-dependent anion channel 22 342 3.5E-46 T 06-07-2017 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 GTHT12_RS18000 b492dfc0cea3fc5b6ef71737e5eb27cd 152 SUPERFAMILY SSF140959 3 144 3.27E-12 T 06-07-2017 GTHT12_RS18000 b492dfc0cea3fc5b6ef71737e5eb27cd 152 Pfam PF08933 Domain of unknown function (DUF1864) 3 114 4.4E-7 T 06-07-2017 IPR015029 Protein of unknown function DUF1864 GTHT12_RS06380 936c744cb6387dc27a9f1575e45c82bf 142 Pfam PF03748 Flagellar basal body-associated protein FliL 51 142 2.4E-21 T 06-07-2017 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 GTHT12_RS09815 8101eb7dbee2a0d9cb64a3e13963279f 220 Gene3D G3DSA:3.40.50.1110 7 212 4.3E-47 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain GTHT12_RS09815 8101eb7dbee2a0d9cb64a3e13963279f 220 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 11 200 7.8E-26 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain GTHT12_RS09815 8101eb7dbee2a0d9cb64a3e13963279f 220 SUPERFAMILY SSF52266 5 213 8.86E-46 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain GTHT12_RS10115 5e2c25b3a3f1d3d7e35504d019682c80 123 Pfam PF13038 Domain of unknown function (DUF3899) 30 118 6.2E-8 T 06-07-2017 IPR025007 Domain of unknown function DUF3899 GTHT12_RS02885 95fe2906fe846fb9701996cc10443f44 522 Pfam PF05598 Transposase domain (DUF772) 49 117 1.6E-22 T 06-07-2017 IPR008490 Transposase InsH, N-terminal GTHT12_RS02885 95fe2906fe846fb9701996cc10443f44 522 Pfam PF13751 Transposase DDE domain 382 506 1.8E-30 T 06-07-2017 IPR025668 Transposase DDE domain GTHT12_RS04005 4bca1138b3220842dd666c2eba455dce 43 Pfam PF13081 Domain of unknown function (DUF3941) 18 41 4.6E-14 T 06-07-2017 IPR025077 Protein of unknown function DUF3941 GTHT12_RS12255 da3750d289b5e4ff13bbae993f5de693 81 Pfam PF13025 Protein of unknown function (DUF3886) 12 79 1.5E-21 T 06-07-2017 IPR024980 Protein of unknown function DUF3886 GTHT12_RS17390 8b8f35e2ab7971d2b79525c32a99ec5e 297 SUPERFAMILY SSF51261 105 213 6.28E-27 T 06-07-2017 IPR011055 Duplicated hybrid motif GTHT12_RS17390 8b8f35e2ab7971d2b79525c32a99ec5e 297 Pfam PF01551 Peptidase family M23 112 210 8.9E-25 T 06-07-2017 IPR016047 Peptidase M23 GTHT12_RS17390 8b8f35e2ab7971d2b79525c32a99ec5e 297 Gene3D G3DSA:2.70.70.10 79 215 3.2E-29 T 06-07-2017 GTHT12_RS14960 d15d920953b640b80e0434e22bbcdf52 208 PIRSF PIRSF006324 1 207 7.1E-58 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 GTHT12_RS14960 d15d920953b640b80e0434e22bbcdf52 208 Pfam PF01810 LysE type translocator 15 204 6.3E-35 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 GTHT12_RS13505 0513243056b59ece283fe771b1703e14 96 Pfam PF13797 Post-transcriptional regulator 6 82 2.5E-28 T 06-07-2017 IPR025716 Post-transcriptional regulator GTHT12_RS07775 46477cff826b5c3ba0a33e7cedbfcbbc 331 Pfam PF01757 Acyltransferase family 6 306 5.9E-19 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 GTHT12_RS00200 4fdec7f736df9ba70651c07c44de5a95 97 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 6.5E-12 T 06-07-2017 IPR007159 SpoVT-AbrB domain GO:0003677 GTHT12_RS00200 4fdec7f736df9ba70651c07c44de5a95 97 SUPERFAMILY SSF89447 1 52 4.71E-17 T 06-07-2017 GTHT12_RS00200 4fdec7f736df9ba70651c07c44de5a95 97 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 2.2E-10 T 06-07-2017 IPR007159 SpoVT-AbrB domain GO:0003677 GTHT12_RS00200 4fdec7f736df9ba70651c07c44de5a95 97 SMART SM00966 8 51 2.4E-10 T 06-07-2017 IPR007159 SpoVT-AbrB domain GO:0003677 GTHT12_RS00200 4fdec7f736df9ba70651c07c44de5a95 97 Gene3D G3DSA:2.10.260.10 1 51 6.7E-30 T 06-07-2017 GTHT12_RS06105 3c8b02755ae46377fb1f78cfbe70c27d 364 PIRSF PIRSF006004 12 364 1.2E-140 T 06-07-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GTHT12_RS06105 3c8b02755ae46377fb1f78cfbe70c27d 364 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 19 364 9.2E-160 T 06-07-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GTHT12_RS06105 3c8b02755ae46377fb1f78cfbe70c27d 364 Gene3D G3DSA:3.20.20.70 111 351 2.2E-15 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 GTHT12_RS06105 3c8b02755ae46377fb1f78cfbe70c27d 364 Pfam PF04055 Radical SAM superfamily 121 289 7.9E-17 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 GTHT12_RS06105 3c8b02755ae46377fb1f78cfbe70c27d 364 SUPERFAMILY SSF102114 101 330 4.05E-14 T 06-07-2017 GTHT12_RS06105 3c8b02755ae46377fb1f78cfbe70c27d 364 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 18 360 75.88 T 06-07-2017 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 GTHT12_RS06105 3c8b02755ae46377fb1f78cfbe70c27d 364 Pfam PF13394 4Fe-4S single cluster domain 126 220 1.6E-5 T 06-07-2017 GTHT12_RS16875 9bcc0d5d047c2663447d9e9409826065 119 Pfam PF14449 Pre-toxin TG 19 87 1.0E-10 T 06-07-2017 IPR027797 Pre-toxin TG domain GTHT12_RS12940 c97b3ecd42463db8be4e5def6b4d6ee8 189 Gene3D G3DSA:3.40.50.1000 156 182 7.7E-14 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS12940 c97b3ecd42463db8be4e5def6b4d6ee8 189 Gene3D G3DSA:3.40.50.1000 65 115 7.7E-14 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS12940 c97b3ecd42463db8be4e5def6b4d6ee8 189 Gene3D G3DSA:3.40.50.1000 5 21 7.7E-14 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS12940 c97b3ecd42463db8be4e5def6b4d6ee8 189 PIRSF PIRSF021362 3 188 4.6E-67 T 06-07-2017 IPR009206 Nucleotidase, putative GTHT12_RS12940 c97b3ecd42463db8be4e5def6b4d6ee8 189 SUPERFAMILY SSF56784 63 163 5.36E-17 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS12940 c97b3ecd42463db8be4e5def6b4d6ee8 189 SUPERFAMILY SSF56784 6 17 5.36E-17 T 06-07-2017 IPR023214 HAD-like domain GTHT12_RS12220 911509b7effde63489b9fa4165f62648 70 Pfam PF14004 Protein of unknown function (DUF4227) 2 70 1.1E-31 T 06-07-2017 IPR025321 Protein of unknown function DUF4227 GTHT12_RS07895 10621aa5b246b1e7953662b06a2a9064 259 Pfam PF10370 Domain of unknown function (DUF2437) 1 50 4.3E-11 T 06-07-2017 IPR018833 Domain of unknown function DUF2437 GTHT12_RS07895 10621aa5b246b1e7953662b06a2a9064 259 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 56 249 3.4E-57 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GTHT12_RS07895 10621aa5b246b1e7953662b06a2a9064 259 Gene3D G3DSA:3.90.850.10 48 252 2.1E-74 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GTHT12_RS07895 10621aa5b246b1e7953662b06a2a9064 259 SUPERFAMILY SSF56529 48 250 1.28E-66 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 GTHT12_RS05075 c2df3204cc5fcc245375f98af48f22c3 67 Pfam PF06130 Phosphate propanoyltransferase 2 56 1.6E-9 T 06-07-2017 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00561+2.3.1.22|KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013|MetaCyc: PWY-7420 GTHT12_RS12170 ef767860ec14705a0b24f78c4ad8bc08 207 Gene3D G3DSA:2.60.480.10 1 96 2.0E-28 T 06-07-2017 GTHT12_RS12170 ef767860ec14705a0b24f78c4ad8bc08 207 Pfam PF12164 Stage V sporulation protein AA 3 88 9.3E-23 T 06-07-2017 IPR021997 Stage V sporulation protein AA GTHT12_RS10990 10f5afd92260bebad347272de19f97b3 240 Pfam PF04519 Polymer-forming cytoskeletal 6 84 1.0E-7 T 06-07-2017 IPR007607 Protein of unknown function DUF583 GTHT12_RS10990 10f5afd92260bebad347272de19f97b3 240 Pfam PF04519 Polymer-forming cytoskeletal 46 119 3.3E-7 T 06-07-2017 IPR007607 Protein of unknown function DUF583 GTHT12_RS15250 806bb9757a18835e59efdd0ec6a368d6 166 SUPERFAMILY SSF55729 6 165 1.2E-36 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS15250 806bb9757a18835e59efdd0ec6a368d6 166 Gene3D G3DSA:3.40.630.30 6 165 1.4E-43 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS15250 806bb9757a18835e59efdd0ec6a368d6 166 Pfam PF13420 Acetyltransferase (GNAT) domain 6 150 1.8E-17 T 06-07-2017 GTHT12_RS17730 5ddc1a9ae18609883995caa4369217aa 433 PIRSF PIRSF005353 1 433 2.5E-163 T 06-07-2017 IPR026033 Purine permease PbuG-like GTHT12_RS17730 5ddc1a9ae18609883995caa4369217aa 433 Pfam PF00860 Permease family 14 394 6.8E-64 T 06-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 GTHT12_RS05505 60f7a921f6a3844fb3b853dd150d1b08 158 Pfam PF00571 CBS domain 86 136 1.8E-6 T 06-07-2017 IPR000644 CBS domain GTHT12_RS05505 60f7a921f6a3844fb3b853dd150d1b08 158 Pfam PF00571 CBS domain 20 71 4.0E-4 T 06-07-2017 IPR000644 CBS domain GTHT12_RS05505 60f7a921f6a3844fb3b853dd150d1b08 158 SUPERFAMILY SSF54631 12 140 1.02E-30 T 06-07-2017 GTHT12_RS05505 60f7a921f6a3844fb3b853dd150d1b08 158 Gene3D G3DSA:3.10.580.10 7 143 7.6E-24 T 06-07-2017 GTHT12_RS10930 d41831aa955aa46c3f88a80621901e01 260 Pfam PF01925 Sulfite exporter TauE/SafE 11 254 1.7E-43 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 GTHT12_RS03495 267773f1192a88a37438f493a146273c 260 Pfam PF02361 Cobalt transport protein 9 218 2.2E-29 T 06-07-2017 IPR003339 ABC/ECF transporter, transmembrane component GTHT12_RS06065 01c0676e95ff869de570df28badc9508 87 Hamap MF_01503 UPF0296 protein . 3 86 28.748 T 06-07-2017 IPR007169 Uncharacterised protein family UPF0296 GTHT12_RS06065 01c0676e95ff869de570df28badc9508 87 ProDom PD063023 UPF0296 YLZA BA4010/GBAA4010/BAS3723 BLI01788/BL02292 BT9727_3613 BC3870 TM1690 CBDBA43 SYC0519_C BCE33L3631 6 77 2.0E-33 T 06-07-2017 IPR007169 Uncharacterised protein family UPF0296 GTHT12_RS06065 01c0676e95ff869de570df28badc9508 87 Pfam PF04025 Domain of unknown function (DUF370) 5 77 4.9E-37 T 06-07-2017 IPR007169 Uncharacterised protein family UPF0296 GTHT12_RS08110 8b8da8f00872fb6ceb87ae8070ac6721 59 Pfam PF14162 YozD-like protein 2 57 2.4E-33 T 06-07-2017 IPR025545 YozD-like protein GTHT12_RS08110 8b8da8f00872fb6ceb87ae8070ac6721 59 ProDom PD052277 YOZD 1 48 4.0E-19 T 06-07-2017 GTHT12_RS01110 2715a2f85e766846daa648f49b0fe50c 25 Pfam PF12323 Helix-turn-helix domain 10 25 5.0E-6 T 06-07-2017 IPR021027 Transposase, putative, helix-turn-helix domain GTHT12_RS10455 e4e0549de5ab0ecd5493ec7a2ec99738 106 Pfam PF08666 SAF domain 13 88 4.0E-18 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 GTHT12_RS10455 e4e0549de5ab0ecd5493ec7a2ec99738 106 SMART SM00858 13 88 1.1E-12 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 GTHT12_RS16040 05c8d3ff506b89bd96d7a3c2bc4e480a 115 Pfam PF09685 Domain of unknown function (DUF4870) 13 109 9.5E-10 T 06-07-2017 IPR019109 Protein of unknown function DUF4870 GTHT12_RS16040 05c8d3ff506b89bd96d7a3c2bc4e480a 115 ProDom PD070949 MEMBRANE PROTEIN YVLA SPANNING SIMILAR SE2241 LMO0604 LMO2177 LIN2280 INTEGRAL 8 115 1.0E-27 T 06-07-2017 GTHT12_RS05330 6f89068dae69423289fa68e1d226031b 81 ProDom PD060056 YUEH 1 81 6.0E-26 T 06-07-2017 IPR020260 Uncharacterised protein family YueH GTHT12_RS05330 6f89068dae69423289fa68e1d226031b 81 Pfam PF14166 YueH-like protein 2 80 2.0E-28 T 06-07-2017 IPR020260 Uncharacterised protein family YueH GTHT12_RS12810 dccc238ed5e1cd15067edc0d803fd4ed 58 ProDom PD052097 RELATED ALKALIPHILY YQGW MEMBRANE TRANSMEMBRANE SPANNING 4 55 8.0E-20 T 06-07-2017 IPR024490 Protein of unknown function DUF2759 GTHT12_RS12810 dccc238ed5e1cd15067edc0d803fd4ed 58 Pfam PF10958 Protein of unknown function (DUF2759) 6 55 7.2E-25 T 06-07-2017 IPR024490 Protein of unknown function DUF2759 GTHT12_RS06760 f5a04f052c3e20b97ba7d2f734020f30 183 Pfam PF10628 Outer spore coat protein E (CotE) 3 178 1.8E-72 T 06-07-2017 IPR018901 Spore coat protein CotE GTHT12_RS05895 baccfe08de1dd143e6a71d728fba97ad 239 Pfam PF05949 Bacterial protein of unknown function (DUF881) 86 230 2.1E-28 T 06-07-2017 IPR010273 Protein of unknown function DUF881 GTHT12_RS17060 2e85c8399afb44553f362508307de283 92 Pfam PF11950 Protein of unknown function (DUF3467) 8 68 8.0E-7 T 06-07-2017 IPR021857 Protein of unknown function DUF3467 GTHT12_RS12375 94a1f28056a7896b62f7b9c8ebeed42e 168 SUPERFAMILY SSF141523 28 151 1.83E-31 T 06-07-2017 GTHT12_RS12375 94a1f28056a7896b62f7b9c8ebeed42e 168 Gene3D G3DSA:2.40.440.10 25 151 7.5E-35 T 06-07-2017 GTHT12_RS12375 94a1f28056a7896b62f7b9c8ebeed42e 168 Pfam PF03734 L,D-transpeptidase catalytic domain 28 150 2.4E-20 T 06-07-2017 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 GTHT12_RS18470 b47c24dbbf8c7295f9dd00ece8030f95 91 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 25 85 5.6E-14 T 06-07-2017 IPR008792 Coenzyme PQQ synthesis D GTHT12_RS07035 0979437c5797fab964dbcfcdf2510512 133 Pfam PF07070 SpoOM protein 3 132 3.8E-34 T 06-07-2017 IPR009776 Sporulation stage 0, protein M GTHT12_RS04940 f9c0fe746c1612ea8d90fd543cc0a1e4 113 Pfam PF04341 Protein of unknown function, DUF485 21 104 2.9E-22 T 06-07-2017 IPR007436 Protein of unknown function DUF485 GTHT12_RS12800 9e0fe398f66eb980dfae5af331b6dab9 375 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 62 299 4.5E-42 T 06-07-2017 IPR003788 Putative S-adenosyl-L-methionine-dependent methyltransferase MidA Reactome: R-HSA-6799198 GTHT12_RS12800 9e0fe398f66eb980dfae5af331b6dab9 375 SUPERFAMILY SSF53335 12 360 2.06E-75 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS13200 fb49aafa4e2e9baa19727f7fdd5845aa 247 Pfam PF13649 Methyltransferase domain 41 136 2.4E-17 T 06-07-2017 GTHT12_RS13200 fb49aafa4e2e9baa19727f7fdd5845aa 247 Gene3D G3DSA:3.40.50.150 3 246 7.8E-39 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS13200 fb49aafa4e2e9baa19727f7fdd5845aa 247 SUPERFAMILY SSF53335 3 246 4.82E-49 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS01185 c1925e92f1c8a4d1aad483aea1b176a6 134 Pfam PF07681 DoxX 9 88 1.6E-19 T 06-07-2017 IPR032808 DoxX family GTHT12_RS05920 7d09a9334a7628a7dd20f9e430dbb668 302 Pfam PF03419 Sporulation factor SpoIIGA 3 292 1.8E-89 T 06-07-2017 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 GTHT12_RS05920 7d09a9334a7628a7dd20f9e430dbb668 302 PIRSF PIRSF018571 1 295 4.5E-86 T 06-07-2017 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 GTHT12_RS05920 7d09a9334a7628a7dd20f9e430dbb668 302 TIGRFAM TIGR02854 spore_II_GA: sigma-E processing peptidase SpoIIGA 2 293 8.1E-94 T 06-07-2017 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 GTHT12_RS01995 35e4bba96fa414c94eeb991c26e4c952 107 Pfam PF03551 Transcriptional regulator PadR-like family 14 83 1.2E-23 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal GTHT12_RS01995 35e4bba96fa414c94eeb991c26e4c952 107 SUPERFAMILY SSF46785 10 100 2.92E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS01995 35e4bba96fa414c94eeb991c26e4c952 107 Gene3D G3DSA:1.10.10.10 1 101 2.9E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS12980 af05db1d878fdd4610d2e140d3a05804 179 Pfam PF14181 YqfQ-like protein 64 179 2.8E-27 T 06-07-2017 IPR025571 YqfQ-like protein GTHT12_RS01245 0e574e3a6aeaaf627221fdf2f6165497 331 Pfam PF07070 SpoOM protein 3 197 4.9E-53 T 06-07-2017 IPR009776 Sporulation stage 0, protein M GTHT12_RS07990 67dea54411ba962d40eb4cb8d7c737e2 372 Pfam PF02687 FtsX-like permease family 253 364 1.3E-15 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 GTHT12_RS16570 9142d79fd357e1a645ebec79c09d56b7 128 SUPERFAMILY SSF54593 1 127 8.19E-35 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GTHT12_RS16570 9142d79fd357e1a645ebec79c09d56b7 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 125 4.2E-22 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain GTHT12_RS16570 9142d79fd357e1a645ebec79c09d56b7 128 Gene3D G3DSA:3.10.180.10 1 127 1.1E-36 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase GTHT12_RS04310 2a264fc63ecc53d8741f37450e6d40cb 309 Gene3D G3DSA:1.10.3720.10 90 299 1.1E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS04310 2a264fc63ecc53d8741f37450e6d40cb 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 303 4.8E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS04310 2a264fc63ecc53d8741f37450e6d40cb 309 SUPERFAMILY SSF161098 91 291 4.36E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS12090 3580ae14cd0b5438ce8f564768f85a6e 170 SUPERFAMILY SSF140663 1 125 5.1E-32 T 06-07-2017 IPR023203 TTHA0068-like domain GTHT12_RS12090 3580ae14cd0b5438ce8f564768f85a6e 170 Gene3D G3DSA:1.10.3450.10 1 126 1.1E-25 T 06-07-2017 IPR023203 TTHA0068-like domain GTHT12_RS12090 3580ae14cd0b5438ce8f564768f85a6e 170 Pfam PF03745 Domain of unknown function (DUF309) 7 63 8.5E-20 T 06-07-2017 IPR005500 Protein of unknown function DUF309 GTHT12_RS09065 6478a5f62fc16e72cbec38ef99717e6f 262 Gene3D G3DSA:1.10.443.10 2 110 5.8E-11 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS09065 6478a5f62fc16e72cbec38ef99717e6f 262 Pfam PF00589 Phage integrase family 71 111 1.8E-6 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 GTHT12_RS09065 6478a5f62fc16e72cbec38ef99717e6f 262 SUPERFAMILY SSF56349 2 42 3.53E-11 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 GTHT12_RS09065 6478a5f62fc16e72cbec38ef99717e6f 262 SUPERFAMILY SSF56349 69 118 3.53E-11 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 GTHT12_RS07515 2ccb722cdd117a74e2d1c083fcf0abb9 75 Pfam PF13217 Protein of unknown function (DUF4025) 3 51 1.3E-20 T 06-07-2017 IPR025100 Protein of unknown function DUF4025 GTHT12_RS17445 70604b437510996ba37033e5da4e0160 333 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 14 332 24.96 T 06-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17445 70604b437510996ba37033e5da4e0160 333 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 216 229 - T 06-07-2017 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17445 70604b437510996ba37033e5da4e0160 333 Pfam PF00146 NADH dehydrogenase 24 326 8.1E-124 T 06-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS05475 96e6e60fafa12f15aad648a17d2e1774 144 Pfam PF14177 YkyB-like protein 7 141 1.4E-65 T 06-07-2017 IPR025552 YkyB-like protein GTHT12_RS13535 2d6485ab73c667c2d91042187c4acd2e 68 Pfam PF11146 Protein of unknown function (DUF2905) 6 63 6.5E-24 T 06-07-2017 IPR021320 Protein of unknown function DUF2905 GTHT12_RS10785 fede7cbab474a94c0a31aab0fbf4c0cb 119 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 11 98 3.3E-28 T 06-07-2017 IPR009359 Phenylacetic acid degradation B GTHT12_RS10785 fede7cbab474a94c0a31aab0fbf4c0cb 119 Pfam PF06243 Phenylacetic acid degradation B 11 96 1.8E-25 T 06-07-2017 IPR009359 Phenylacetic acid degradation B GTHT12_RS01045 592eaa9b73a3251dc17a37a2408902b1 68 Gene3D G3DSA:3.90.820.10 10 65 3.3E-29 T 06-07-2017 GTHT12_RS01045 592eaa9b73a3251dc17a37a2408902b1 68 SMART SM00923 3 53 1.1E-26 T 06-07-2017 IPR005153 MbtH-like protein GTHT12_RS01045 592eaa9b73a3251dc17a37a2408902b1 68 Pfam PF03621 MbtH-like protein 1 52 3.1E-26 T 06-07-2017 IPR005153 MbtH-like protein GTHT12_RS01045 592eaa9b73a3251dc17a37a2408902b1 68 SUPERFAMILY SSF160582 1 66 1.07E-29 T 06-07-2017 GTHT12_RS07500 9082b8ceddbc459db006c3e8f90bb010 214 Pfam PF10112 5-bromo-4-chloroindolyl phosphate hydrolysis protein 8 195 1.1E-52 T 06-07-2017 IPR018770 5-bromo-4-chloroindolyl phosphate hydrolysis protein GTHT12_RS04170 86bc24f6b6e5673eec975d749c277c2b 166 SUPERFAMILY SSF52540 2 162 1.9E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS04170 86bc24f6b6e5673eec975d749c277c2b 166 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 3 133 1.1E-27 T 06-07-2017 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 GTHT12_RS04170 86bc24f6b6e5673eec975d749c277c2b 166 Gene3D G3DSA:3.40.50.300 1 163 1.1E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS04170 86bc24f6b6e5673eec975d749c277c2b 166 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 5 133 3.0E-33 T 06-07-2017 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 GTHT12_RS03120 8f979fa826c26b5cb6e0745a068b9bd4 263 Pfam PF06182 ABC-2 family transporter protein 31 262 1.0E-18 T 06-07-2017 IPR010390 Protein of unknown function DUF990 GTHT12_RS04490 3d4300d34b16cfe4c37810bb8e1064bb 112 Gene3D G3DSA:1.20.5.490 17 44 8.4E-4 T 06-07-2017 GTHT12_RS06995 07bdcab111055924dd6a72e0f1b75e42 45 TIGRFAM TIGR03093 SASP_sspL: small, acid-soluble spore protein L 9 45 1.7E-21 T 06-07-2017 IPR017526 Small acid-soluble spore protein, SspL GTHT12_RS05730 7302990e5aba50a74c65a4f5713e8597 119 Pfam PF08868 YugN-like family 5 105 4.1E-17 T 06-07-2017 IPR014967 Uncharacterised protein family, YugN-like GTHT12_RS05730 7302990e5aba50a74c65a4f5713e8597 119 Gene3D G3DSA:3.30.310.100 1 117 7.6E-48 T 06-07-2017 IPR014967 Uncharacterised protein family, YugN-like GTHT12_RS05730 7302990e5aba50a74c65a4f5713e8597 119 SUPERFAMILY SSF160755 1 114 9.68E-44 T 06-07-2017 IPR014967 Uncharacterised protein family, YugN-like GTHT12_RS16810 4c94d134a3131793247f14efb3c57441 294 Pfam PF00483 Nucleotidyl transferase 6 262 5.7E-34 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 GTHT12_RS16810 4c94d134a3131793247f14efb3c57441 294 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 263 2.5E-119 T 06-07-2017 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 GTHT12_RS16810 4c94d134a3131793247f14efb3c57441 294 Gene3D G3DSA:3.90.550.10 5 273 4.9E-76 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS16810 4c94d134a3131793247f14efb3c57441 294 SUPERFAMILY SSF53448 1 268 8.23E-70 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases GTHT12_RS04280 82eab3759d419aa6088d8e20720ad236 263 Pfam PF10026 Predicted Zn-dependent protease (DUF2268) 64 254 5.0E-57 T 06-07-2017 IPR018728 Domain of unknown function DUF2268 GTHT12_RS04185 1b640f397ce016e5373763b37ff468fd 242 Pfam PF14256 YwiC-like protein 9 132 1.5E-40 T 06-07-2017 IPR025576 YwiC-like protein GTHT12_RS06840 6fadde7f9a0c874e3bb1c8d4d8ecefe1 292 SUPERFAMILY SSF103481 207 289 1.2E-18 T 06-07-2017 GTHT12_RS06840 6fadde7f9a0c874e3bb1c8d4d8ecefe1 292 SUPERFAMILY SSF103481 40 141 4.71E-17 T 06-07-2017 GTHT12_RS06840 6fadde7f9a0c874e3bb1c8d4d8ecefe1 292 Pfam PF00892 EamA-like transporter family 10 139 2.0E-24 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 GTHT12_RS06840 6fadde7f9a0c874e3bb1c8d4d8ecefe1 292 Pfam PF00892 EamA-like transporter family 151 286 6.6E-24 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 GTHT12_RS18485 2ace53f7bd3d760b1efda7d732b97b51 210 Pfam PF01928 CYTH domain 12 185 8.3E-20 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 GTHT12_RS18485 2ace53f7bd3d760b1efda7d732b97b51 210 Gene3D G3DSA:2.40.320.10 13 186 1.6E-16 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 GTHT12_RS18485 2ace53f7bd3d760b1efda7d732b97b51 210 SUPERFAMILY SSF55154 12 182 1.96E-28 T 06-07-2017 IPR033469 CYTH-like domain Reactome: R-HSA-196819 GTHT12_RS18485 2ace53f7bd3d760b1efda7d732b97b51 210 SMART SM01118 12 194 1.0E-11 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 GTHT12_RS02655 f5e6e285fdbe63902f3777de1ee455b0 115 SUPERFAMILY SSF140453 30 101 2.75E-6 T 06-07-2017 IPR010310 Type VII secretion system ESAT-6-like GTHT12_RS02655 f5e6e285fdbe63902f3777de1ee455b0 115 Pfam PF16888 Domain of unknown function (DUF5082) 21 114 6.6E-8 T 06-07-2017 IPR031681 Protein of unknown function DUF5082 GTHT12_RS10505 e1b8c6ea4a8ebdf7baf6338fa2c4d265 417 Pfam PF09861 Domain of unknown function (DUF2088) 28 191 5.9E-15 T 06-07-2017 IPR018657 Domain of unknown function DUF2088 GTHT12_RS00125 69e343ebc4440718e158f10634ec75fa 74 Pfam PF10704 Protein of unknown function (DUF2508) 3 69 2.3E-23 T 06-07-2017 IPR019644 Protein of unknown function DUF2508 GTHT12_RS03040 58dc7cd702a295645237883132418476 292 Pfam PF13612 Transposase DDE domain 111 267 3.7E-28 T 06-07-2017 IPR025668 Transposase DDE domain GTHT12_RS18480 4271cacd6007a8c2e125fedfa2147aef 238 Pfam PF02517 CAAX protease self-immunity 131 220 2.6E-9 T 06-07-2017 IPR003675 CAAX amino terminal protease GO:0016020 GTHT12_RS02505 1db6f00dbbbe21d8ea9f569d7ec683b6 262 Pfam PF14167 YfkD-like protein 31 262 5.3E-119 T 06-07-2017 IPR025548 YfkD-like protein GTHT12_RS01890 797a33ebf73a5b5b34cba02c4716085e 99 ProDom PD745092 MEMBRANE YHDT SODIUM/PANTOTHENATE TRANSMEMBRANE INNER SYMPORTER Y0210 INTEGRAL PROTEIN-LIKE PM1090 9 72 4.0E-21 T 06-07-2017 IPR010398 Protein of unknown function DUF997 GTHT12_RS01890 797a33ebf73a5b5b34cba02c4716085e 99 Pfam PF06196 Protein of unknown function (DUF997) 14 90 2.8E-29 T 06-07-2017 IPR010398 Protein of unknown function DUF997 GTHT12_RS05965 72ae3318d97d83511c79d58ded47e4b0 177 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 10 43 7.5E-18 T 06-07-2017 IPR019933 DivIVA domain GTHT12_RS05965 72ae3318d97d83511c79d58ded47e4b0 177 Pfam PF05103 DivIVA protein 10 140 1.6E-54 T 06-07-2017 IPR007793 DivIVA family GTHT12_RS12695 f9dfeef14fbc0db916bd632f490eb9e3 149 Gene3D G3DSA:1.10.10.60 68 100 6.5E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS10595 144bf7735710fe66ad3c87a9e6516c17 325 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 17 297 1.4E-17 T 06-07-2017 IPR016833 Putative sodium bile acid cotransporter GTHT12_RS15225 63fe4f46ee15fcbb20273a711c777945 225 Pfam PF02308 MgtC family 9 136 5.3E-33 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 GTHT12_RS15225 63fe4f46ee15fcbb20273a711c777945 225 PRINTS PR01837 MgtC/SapB protein signature 93 117 2.5E-42 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 GTHT12_RS15225 63fe4f46ee15fcbb20273a711c777945 225 PRINTS PR01837 MgtC/SapB protein signature 31 49 2.5E-42 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 GTHT12_RS15225 63fe4f46ee15fcbb20273a711c777945 225 PRINTS PR01837 MgtC/SapB protein signature 65 87 2.5E-42 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 GTHT12_RS15225 63fe4f46ee15fcbb20273a711c777945 225 PRINTS PR01837 MgtC/SapB protein signature 12 31 2.5E-42 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 GTHT12_RS15220 3dd3a22609b840ea1ab0b17f40ba021a 302 SUPERFAMILY SSF103481 191 288 7.19E-15 T 06-07-2017 GTHT12_RS15220 3dd3a22609b840ea1ab0b17f40ba021a 302 SUPERFAMILY SSF103481 40 143 2.88E-16 T 06-07-2017 GTHT12_RS15220 3dd3a22609b840ea1ab0b17f40ba021a 302 Pfam PF00892 EamA-like transporter family 151 285 9.4E-21 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 GTHT12_RS15220 3dd3a22609b840ea1ab0b17f40ba021a 302 Pfam PF00892 EamA-like transporter family 9 139 3.2E-17 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 GTHT12_RS12840 c9f699d74b25cd3b2128becfe5afdb22 386 Pfam PF01694 Rhomboid family 220 356 3.0E-36 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 GTHT12_RS12840 c9f699d74b25cd3b2128becfe5afdb22 386 Gene3D G3DSA:1.20.1540.10 179 354 2.1E-44 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 GTHT12_RS12840 c9f699d74b25cd3b2128becfe5afdb22 386 SUPERFAMILY SSF144091 177 357 4.97E-46 T 06-07-2017 GTHT12_RS15830 dbc4725bb49313b78aa120e7a4b93165 299 Gene3D G3DSA:1.20.1260.10 3 196 3.3E-59 T 06-07-2017 IPR012347 Ferritin-related GTHT12_RS15830 dbc4725bb49313b78aa120e7a4b93165 299 Pfam PF05067 Manganese containing catalase 5 297 3.4E-95 T 06-07-2017 IPR007760 Manganese catalase GTHT12_RS15830 dbc4725bb49313b78aa120e7a4b93165 299 SUPERFAMILY SSF47240 3 294 3.45E-96 T 06-07-2017 IPR009078 Ferritin-like superfamily GTHT12_RS00160 b190005af50277135227a7d25909a19b 68 Pfam PF10764 Inhibitor of sigma-G Gin 15 59 1.0E-19 T 06-07-2017 IPR019700 Anti-sigma-G factor Gin GTHT12_RS17080 a9c2a3bf3466524dd1a173f8bdb304e8 253 Pfam PF03167 Uracil DNA glycosylase superfamily 132 202 3.3E-5 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 GTHT12_RS11415 4173b0248a8bf8c845d8adc2f48052f7 188 PIRSF PIRSF016897 1 184 1.7E-62 T 06-07-2017 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 GTHT12_RS11415 4173b0248a8bf8c845d8adc2f48052f7 188 SUPERFAMILY SSF110391 7 180 9.94E-60 T 06-07-2017 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 GTHT12_RS11415 4173b0248a8bf8c845d8adc2f48052f7 188 Gene3D G3DSA:3.20.20.400 3 181 2.3E-68 T 06-07-2017 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 GTHT12_RS11415 4173b0248a8bf8c845d8adc2f48052f7 188 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 7 179 4.5E-63 T 06-07-2017 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 GTHT12_RS09575 bb2f60823642d1dfda3a6d0ca789c6f0 234 SUPERFAMILY SSF103501 3 222 1.7E-71 T 06-07-2017 IPR023234 NarG-like domain GTHT12_RS09575 bb2f60823642d1dfda3a6d0ca789c6f0 234 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 2 222 2.2E-81 T 06-07-2017 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 GTHT12_RS09575 bb2f60823642d1dfda3a6d0ca789c6f0 234 Pfam PF02665 Nitrate reductase gamma subunit 4 222 1.2E-86 T 06-07-2017 IPR023234 NarG-like domain GTHT12_RS09575 bb2f60823642d1dfda3a6d0ca789c6f0 234 Gene3D G3DSA:1.20.950.20 2 214 3.0E-75 T 06-07-2017 GTHT12_RS07015 ef327955d9d2dd4f5075501cfe39f8a8 71 Pfam PF10782 Zinc-finger 7 62 2.9E-29 T 06-07-2017 IPR019718 Protein of unknown function DUF2602 GTHT12_RS08175 96c57c30a6663a5eaf2f44b67198c467 46 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 22 46 4.3E-14 T 06-07-2017 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM GTHT12_RS08175 96c57c30a6663a5eaf2f44b67198c467 46 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 23 46 1.1E-12 T 06-07-2017 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM GTHT12_RS17360 ed0af2c00fc655203b2bd8a42046939d 177 Pfam PF02417 Chromate transporter 4 172 6.9E-39 T 06-07-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 GTHT12_RS11015 2872cb223fc5b1d1cb3f9f3dc4cb8776 131 Pfam PF07282 Putative transposase DNA-binding domain 59 111 1.9E-10 T 06-07-2017 IPR010095 Transposase IS605, OrfB, C-terminal GTHT12_RS16755 c4e675fe76fbd78f81dd1349b886928a 439 SUPERFAMILY SSF103642 5 25 3.43E-6 T 06-07-2017 GTHT12_RS16755 c4e675fe76fbd78f81dd1349b886928a 439 Pfam PF02810 SEC-C motif 6 24 6.5E-7 T 06-07-2017 IPR004027 SEC-C motif GTHT12_RS16755 c4e675fe76fbd78f81dd1349b886928a 439 Gene3D G3DSA:3.10.450.50 3 24 1.8E-6 T 06-07-2017 IPR032710 NTF2-like domain GTHT12_RS07345 ff4a92d00afff241b93778dae1541715 251 Gene3D G3DSA:3.40.50.300 1 227 1.2E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07345 ff4a92d00afff241b93778dae1541715 251 Pfam PF00005 ABC transporter 18 164 1.9E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 GTHT12_RS07345 ff4a92d00afff241b93778dae1541715 251 SUPERFAMILY SSF52540 2 226 3.9E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07345 ff4a92d00afff241b93778dae1541715 251 SMART SM00382 26 213 3.0E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS17985 176882b09626e3df60f04d89b0cfe345 234 Gene3D G3DSA:3.20.20.370 7 230 4.7E-57 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 GTHT12_RS17985 176882b09626e3df60f04d89b0cfe345 234 Pfam PF01522 Polysaccharide deacetylase 42 147 1.6E-30 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 GTHT12_RS17985 176882b09626e3df60f04d89b0cfe345 234 SUPERFAMILY SSF88713 36 231 1.78E-51 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 GTHT12_RS15675 6bac462b3d39cfb0db5b4990abaffa01 49 Pfam PF14115 YuzL-like protein 3 43 6.7E-22 T 06-07-2017 IPR025625 YuzL-like protein GTHT12_RS08040 bb3f987d1c364cdfbc3c1bfaf0da454d 43 Pfam PF13040 Fur-regulated basic protein B 2 39 3.6E-15 T 06-07-2017 IPR025004 Transcriptional regulatory protein SenN/SenS GTHT12_RS05305 96ad9eb9b5c3e19b3ed169ac6ae5d3f5 141 Pfam PF13508 Acetyltransferase (GNAT) domain 38 118 3.6E-8 T 06-07-2017 IPR000182 GNAT domain GO:0008080 GTHT12_RS05305 96ad9eb9b5c3e19b3ed169ac6ae5d3f5 141 Gene3D G3DSA:3.40.630.30 3 138 8.5E-40 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS05305 96ad9eb9b5c3e19b3ed169ac6ae5d3f5 141 SUPERFAMILY SSF55729 4 139 1.89E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase GTHT12_RS07505 249d46d1a476544c83765c1e7ef0c6ca 398 PIRSF PIRSF026508 24 398 8.0E-119 T 06-07-2017 IPR008863 Toxic anion resistance GTHT12_RS07505 249d46d1a476544c83765c1e7ef0c6ca 398 Pfam PF05816 Toxic anion resistance protein (TelA) 64 391 3.0E-128 T 06-07-2017 IPR008863 Toxic anion resistance GTHT12_RS03805 ea57c8499cf4d7cdf3342706447d3dae 73 Pfam PF10676 Spore germination protein gerPA/gerPF 1 72 1.8E-29 T 06-07-2017 IPR019618 Spore germination protein GerPA/GerPF GTHT12_RS08115 597c0f4e4dd5b313af3ab41ff63b97a3 373 Pfam PF10720 Protein of unknown function (DUF2515) 57 364 1.3E-124 T 06-07-2017 IPR019658 Protein of unknown function DUF2515 GTHT12_RS08565 fb0d45d8ea576d6065e92f25569d5d10 345 Pfam PF02653 Branched-chain amino acid transport system / permease component 31 292 1.9E-37 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 GTHT12_RS15385 969366dc08bda372bdf2bfc745c68100 206 Pfam PF01865 Protein of unknown function DUF47 8 203 3.4E-22 T 06-07-2017 IPR018445 Putative phosphate transport regulator GTHT12_RS15495 5b1988ebef0d99d2355dfdcd2435b3d1 89 Pfam PF11256 Protein of unknown function (DUF3055) 7 85 2.9E-36 T 06-07-2017 IPR021415 Protein of unknown function DUF3055 GTHT12_RS08900 7a1417faf085352c5bad10f091b0bb0e 291 SUPERFAMILY SSF53335 19 278 1.48E-25 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS08900 7a1417faf085352c5bad10f091b0bb0e 291 Pfam PF13649 Methyltransferase domain 104 174 2.8E-9 T 06-07-2017 GTHT12_RS08900 7a1417faf085352c5bad10f091b0bb0e 291 PIRSF PIRSF018249 4 290 5.2E-81 T 06-07-2017 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 GTHT12_RS08900 7a1417faf085352c5bad10f091b0bb0e 291 Gene3D G3DSA:3.40.50.150 76 244 1.1E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase GTHT12_RS16695 95487e1287c49ff3bfdc38e2889946ff 387 Pfam PF05684 Protein of unknown function (DUF819) 11 386 6.1E-124 T 06-07-2017 IPR008537 Protein of unknown function DUF819 GTHT12_RS18070 f7bff4d5a61a45e772b1838d9ff9687c 85 Pfam PF13133 Protein of unknown function (DUF3949) 19 79 2.5E-30 T 06-07-2017 IPR025032 Protein of unknown function DUF3949 GTHT12_RS01015 713a4f5bf9ad7276fad4dab911f649e0 337 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 225 2.6E-8 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS01015 713a4f5bf9ad7276fad4dab911f649e0 337 Gene3D G3DSA:1.10.3720.10 75 300 9.5E-10 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS01015 713a4f5bf9ad7276fad4dab911f649e0 337 SUPERFAMILY SSF161098 76 229 1.14E-10 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS15375 1c37834d36d56c5016721e1cb63e93b9 202 Pfam PF02632 BioY family 39 187 8.9E-37 T 06-07-2017 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 GTHT12_RS15375 1c37834d36d56c5016721e1cb63e93b9 202 PIRSF PIRSF016661 1 196 2.8E-54 T 06-07-2017 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 GTHT12_RS05100 c4b4085f8916262057d1e3aee9b4f62a 389 ProSitePatterns PS01007 Transposases, Mutator family, signature. 221 245 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS05100 c4b4085f8916262057d1e3aee9b4f62a 389 Pfam PF00872 Transposase, Mutator family 15 366 1.3E-98 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS16950 22f16566a48f1ac92b384c9552326d9d 267 Pfam PF01061 ABC-2 type transporter 18 225 1.4E-23 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 GTHT12_RS06670 b52f73eebcb8f3d620f6a66e9d35978f 319 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 297 2.6E-41 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 GTHT12_RS07630 42c00168736367ee0ab98de83ac4592b 257 Pfam PF06182 ABC-2 family transporter protein 54 254 1.9E-19 T 06-07-2017 IPR010390 Protein of unknown function DUF990 GTHT12_RS00835 46d7a7db0b0fe59678d433a7b4ba3cec 146 Pfam PF10730 Protein of unknown function (DUF2521) 1 146 1.3E-64 T 06-07-2017 IPR019667 Uncharacterised protein family YbaK GTHT12_RS14865 4e42a7edd046c631c2e91db331cce707 96 PIRSF PIRSF020408 2 96 5.9E-38 T 06-07-2017 IPR016772 Uncharacterised conserved protein UCP020408 GTHT12_RS14865 4e42a7edd046c631c2e91db331cce707 96 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 3 91 1.3E-18 T 06-07-2017 IPR016772 Uncharacterised conserved protein UCP020408 GTHT12_RS09305 60b48e99e65fe06e93f11b4dbc6258ec 257 SUPERFAMILY SSF52266 43 250 5.5E-35 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain GTHT12_RS09305 60b48e99e65fe06e93f11b4dbc6258ec 257 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 50 238 8.7E-27 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain GTHT12_RS09305 60b48e99e65fe06e93f11b4dbc6258ec 257 Gene3D G3DSA:3.40.50.1110 44 252 1.4E-40 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain GTHT12_RS12640 9782faf25dcca45b7b1899fd1a178257 341 TIGRFAM TIGR04070 photo_TT_lyase: spore photoproduct lyase 4 341 7.4E-154 T 06-07-2017 IPR023897 Spore photoproduct lyase GO:0003913 GTHT12_RS16440 0fafb6bfc2f2d631a470ea6c829cdc56 322 TIGRFAM TIGR04383 acidic_w_LPXTA: processed acidic surface protein 14 318 3.3E-113 T 06-07-2017 IPR030832 Processed acidic surface protein GTHT12_RS03655 391d8f4eea4ebd59a7ce84008539bb3c 29 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 5 27 2.0E-13 T 06-07-2017 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM GTHT12_RS03655 391d8f4eea4ebd59a7ce84008539bb3c 29 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 4 25 2.8E-12 T 06-07-2017 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM GTHT12_RS18045 6d169029c0df6392e6a174df71c90355 167 Gene3D G3DSA:3.40.1710.10 44 128 8.9E-6 T 06-07-2017 GTHT12_RS17025 49b0718711579c0eeefc5ece14816413 103 Pfam PF01527 Transposase 2 77 3.9E-15 T 06-07-2017 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 GTHT12_RS17025 49b0718711579c0eeefc5ece14816413 103 Gene3D G3DSA:1.10.10.60 7 91 1.8E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS17025 49b0718711579c0eeefc5ece14816413 103 SUPERFAMILY SSF46689 1 90 6.81E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS13745 937216b538217d6cab9b751c91306e77 203 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 13 33 - T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site GTHT12_RS15400 e825f0373f920b997618c7a623318d22 219 Pfam PF06725 3D domain 125 186 1.3E-18 T 06-07-2017 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 GTHT12_RS15400 e825f0373f920b997618c7a623318d22 219 SUPERFAMILY SSF50685 125 166 3.84E-7 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain GTHT12_RS17795 d2f043d26e7b4f3acc5dc2cca808440e 123 Pfam PF04241 Protein of unknown function (DUF423) 18 105 4.7E-32 T 06-07-2017 IPR006696 Protein of unknown function DUF423 GTHT12_RS03730 aadf5b9c1c118bd23f817e6426f2e0ea 330 Pfam PF02653 Branched-chain amino acid transport system / permease component 2 268 1.4E-28 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 GTHT12_RS00335 b666cf369a04cb46796f69dafbf835b9 123 Pfam PF04977 Septum formation initiator 45 122 2.9E-19 T 06-07-2017 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 GTHT12_RS09915 13dfe6b6cbdf5618a9617abcfeb62475 289 Gene3D G3DSA:1.10.3720.10 58 286 2.0E-59 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS09915 13dfe6b6cbdf5618a9617abcfeb62475 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 279 4.0E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS09915 13dfe6b6cbdf5618a9617abcfeb62475 289 SUPERFAMILY SSF161098 52 276 1.7E-57 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS16360 b864380e3e6b194aec04ea8ff3ffb829 264 Pfam PF01061 ABC-2 type transporter 18 223 1.6E-19 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 GTHT12_RS15745 c3c7bcab9d06876dd2742e6f39254c92 165 Pfam PF08905 Domain of unknown function (DUF1850) 45 135 6.8E-19 T 06-07-2017 IPR015001 Protein of unknown function DUF1850 GTHT12_RS06645 dfe34cc7909cb91eabb10dc4c11e38ce 779 SUPERFAMILY SSF46785 710 775 1.45E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain GTHT12_RS06645 dfe34cc7909cb91eabb10dc4c11e38ce 779 Pfam PF01580 FtsK/SpoIIIE family 417 613 9.6E-64 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 GTHT12_RS06645 dfe34cc7909cb91eabb10dc4c11e38ce 779 SMART SM00382 452 634 4.7E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain GTHT12_RS06645 dfe34cc7909cb91eabb10dc4c11e38ce 779 SMART SM00843 708 773 2.5E-41 T 06-07-2017 IPR018541 FtsK gamma domain GTHT12_RS06645 dfe34cc7909cb91eabb10dc4c11e38ce 779 Gene3D G3DSA:3.40.50.300 390 679 2.5E-91 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS06645 dfe34cc7909cb91eabb10dc4c11e38ce 779 Pfam PF09397 Ftsk gamma domain 711 770 1.1E-30 T 06-07-2017 IPR018541 FtsK gamma domain GTHT12_RS06645 dfe34cc7909cb91eabb10dc4c11e38ce 779 SUPERFAMILY SSF52540 390 685 9.2E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS12625 0e131805f8db55f945adffeb60a1ba81 118 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 6 118 5.0E-49 T 06-07-2017 GTHT12_RS09290 cb0115962de122e3213c6a143fa5886c 197 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 4 191 20.64 T 06-07-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 GTHT12_RS09290 cb0115962de122e3213c6a143fa5886c 197 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 3 192 1.8E-65 T 06-07-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 GTHT12_RS09290 cb0115962de122e3213c6a143fa5886c 197 SMART SM01207 7 183 2.8E-83 T 06-07-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 GTHT12_RS09290 cb0115962de122e3213c6a143fa5886c 197 Pfam PF02660 Glycerol-3-phosphate acyltransferase 8 182 1.2E-52 T 06-07-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 GTHT12_RS09385 661cc1c46082bcec8df101fc88364e3e 31 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 3 26 3.8E-15 T 06-07-2017 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM GTHT12_RS09385 661cc1c46082bcec8df101fc88364e3e 31 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 4 26 5.0E-13 T 06-07-2017 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM GTHT12_RS11745 0ff13273a1be0715be8834d187718139 300 ProDom PD128584 YPHB BH1976 TRANSMEMBRANE MEMBRANE SEAA 1 293 2.0E-142 T 06-07-2017 GTHT12_RS11745 0ff13273a1be0715be8834d187718139 300 Pfam PF14045 YIEGIA protein 8 287 7.9E-128 T 06-07-2017 IPR025918 YIEGIA protein GTHT12_RS16180 e944bd80d1cadfb31c953777c798705c 388 ProSitePatterns PS01007 Transposases, Mutator family, signature. 220 244 - T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS16180 e944bd80d1cadfb31c953777c798705c 388 Pfam PF00872 Transposase, Mutator family 13 365 6.3E-100 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS15045 9ed909287bba02c4ce9398ea59b94bea 94 Pfam PF00872 Transposase, Mutator family 1 85 7.7E-27 T 06-07-2017 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 GTHT12_RS16830 e32e7fba49c59cb451390ef1f10fbb91 276 Gene3D G3DSA:1.10.3720.10 5 264 3.2E-55 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS16830 e32e7fba49c59cb451390ef1f10fbb91 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 266 1.8E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS16830 e32e7fba49c59cb451390ef1f10fbb91 276 SUPERFAMILY SSF161098 5 271 1.96E-60 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 GTHT12_RS01560 cb0aea363c2088d8a7d7cff361f62ef8 441 PIRSF PIRSF005353 1 441 3.3E-175 T 06-07-2017 IPR026033 Purine permease PbuG-like GTHT12_RS01560 cb0aea363c2088d8a7d7cff361f62ef8 441 Pfam PF00860 Permease family 16 401 2.6E-45 T 06-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 GTHT12_RS02150 f15a8bb83b9c01cbd072de189e29acec 538 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 375 488 3.1E-36 T 06-07-2017 IPR025299 CstA, C-terminal domain GTHT12_RS02150 f15a8bb83b9c01cbd072de189e29acec 538 Pfam PF02554 Carbon starvation protein CstA 1 347 3.9E-130 T 06-07-2017 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 GTHT12_RS12755 5664f739fb45eca2e2b5910dd2033022 129 Pfam PF14173 ComG operon protein 7 30 126 7.3E-23 T 06-07-2017 IPR020372 Competence operon G protein 7, ComGG GTHT12_RS16610 8ba9fe7a6a136a547bbf97afbfd5106a 127 Pfam PF07098 Protein of unknown function (DUF1360) 12 109 2.5E-32 T 06-07-2017 IPR010773 Mycobacterium phage PG1, Gp7 GTHT12_RS03105 75c685972e54f66a7728d43ed9e949ac 172 Pfam PF13612 Transposase DDE domain 111 166 9.9E-8 T 06-07-2017 IPR025668 Transposase DDE domain GTHT12_RS18845 e55fab099ccffbdfed22a1a9de5a7a66 71 Pfam PF11213 Protein of unknown function (DUF3006) 3 69 2.9E-27 T 06-07-2017 IPR021377 Protein of unknown function DUF3006 GTHT12_RS02860 b57e823884d94794daa3a37b364e37fe 105 Pfam PF12986 Domain of unknown function (DUF3870) 5 97 5.7E-30 T 06-07-2017 IPR024617 Domain of unknown function DUF3870 GTHT12_RS12705 b2f299e23731965e987b938af70d84b0 278 Hamap MF_02118 Octanoyltransferase LipM [lipM]. 3 278 68.629 T 06-07-2017 IPR024898 Octanoyltransferase LipM GO:0009107|GO:0009249|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 GTHT12_RS12705 b2f299e23731965e987b938af70d84b0 278 Gene3D G3DSA:3.90.1550.10 2 276 4.9E-66 T 06-07-2017 GTHT12_RS12705 b2f299e23731965e987b938af70d84b0 278 Pfam PF03099 Biotin/lipoate A/B protein ligase family 52 189 9.4E-27 T 06-07-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 GTHT12_RS12705 b2f299e23731965e987b938af70d84b0 278 SUPERFAMILY SSF55681 5 278 3.4E-71 T 06-07-2017 GTHT12_RS03585 db1f1c3ee2bb374620bafe69e777bad0 119 SUPERFAMILY SSF158622 5 113 3.53E-29 T 06-07-2017 IPR023378 YheA/YmcA-like domain GTHT12_RS03585 db1f1c3ee2bb374620bafe69e777bad0 119 Gene3D G3DSA:1.20.1500.10 3 113 1.9E-30 T 06-07-2017 IPR023378 YheA/YmcA-like domain GTHT12_RS03585 db1f1c3ee2bb374620bafe69e777bad0 119 Hamap MF_01526 UPF0342 protein . 2 113 15.94 T 06-07-2017 IPR010368 Control of competence regulator ComK, YlbF/YmcA GTHT12_RS03585 db1f1c3ee2bb374620bafe69e777bad0 119 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 8 108 2.1E-16 T 06-07-2017 IPR010368 Control of competence regulator ComK, YlbF/YmcA GTHT12_RS15770 d4345aed5ce37f4a8644e20f23267d19 356 Pfam PF02653 Branched-chain amino acid transport system / permease component 38 311 1.1E-43 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 GTHT12_RS04045 f7fb9779600680accf97f27c6a5f60d4 416 SUPERFAMILY SSF81442 57 142 7.85E-9 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 GTHT12_RS16635 f98baa21a7b4efd9496e88c3c7bb93dd 479 Pfam PF00324 Amino acid permease 27 437 6.0E-88 T 06-07-2017 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 GTHT12_RS16635 f98baa21a7b4efd9496e88c3c7bb93dd 479 PIRSF PIRSF006060 1 478 2.1E-75 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 GTHT12_RS16635 f98baa21a7b4efd9496e88c3c7bb93dd 479 ProSitePatterns PS00218 Amino acid permeases signature. 51 81 - T 06-07-2017 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 GTHT12_RS16450 3664e6488b6b8107f36d29caefa4b455 144 Pfam PF06935 Protein of unknown function (DUF1284) 21 125 4.2E-22 T 06-07-2017 IPR009702 Protein of unknown function DUF1284 GTHT12_RS08475 90134844b9b3cfe3570029ba6600e4f5 326 Pfam PF12679 ABC-2 family transporter protein 4 325 8.7E-27 T 06-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 GTHT12_RS04880 c0f1b075d3f1d175e5d85f17e16f3931 84 TIGRFAM TIGR04536 geobac_encap: encapsulated protein 3 84 6.0E-32 T 06-07-2017 IPR030909 Encapsulated protein GTHT12_RS17155 d4b7f34348b18d630196db6146d6596b 153 Pfam PF04892 VanZ like family 18 146 4.0E-16 T 06-07-2017 IPR006976 VanZ-like GTHT12_RS12125 5ff02413e767141f42740e932200c0e4 291 Pfam PF06207 Protein of unknown function (DUF1002) 34 251 3.3E-82 T 06-07-2017 IPR009343 Protein of unknown function DUF1002 GTHT12_RS07540 38c9b1288948017e805f295709f41142 162 Pfam PF13798 Protein of unknown function with PCYCGC motif 11 160 3.4E-71 T 06-07-2017 IPR025673 Protein of unknown function with PCYCGC motif GTHT12_RS00330 0768a2293908ab32ed7f9104a0a18c4c 210 Pfam PF09578 Spore cortex protein YabQ (Spore_YabQ) 11 87 3.0E-21 T 06-07-2017 IPR019074 Spore cortex biosynthesis protein, YabQ-like GTHT12_RS00330 0768a2293908ab32ed7f9104a0a18c4c 210 TIGRFAM TIGR02893 spore_yabQ: spore cortex biosynthesis protein YabQ 2 129 6.3E-45 T 06-07-2017 IPR014242 Spore cortex biosynthesis protein, YabQ GTHT12_RS04555 74eb69abf7b11e5a50a3c72246332c20 85 Pfam PF14069 Stage VI sporulation protein F 6 77 4.1E-28 T 06-07-2017 IPR025942 Stage VI sporulation protein F GTHT12_RS05010 fce83c17c69a436b130482c3467183d5 337 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 329 3.1E-48 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 GTHT12_RS12920 629751723621cd5291877dd900462595 257 Pfam PF06691 Protein of unknown function (DUF1189) 4 247 1.3E-75 T 06-07-2017 IPR009574 Protein of unknown function DUF1189 GTHT12_RS10885 dbb811fb1496b1ed7823f2bdd4f1ab25 247 Pfam PF12730 ABC-2 family transporter protein 4 181 1.9E-24 T 06-07-2017 IPR032688 ABC-2 family transporter protein GO:0006810 GTHT12_RS10355 30bf4bb543515b2994b38042cbc77867 308 Pfam PF03547 Membrane transport protein 161 297 1.9E-14 T 06-07-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 GTHT12_RS16685 974955a418aac1dd403d596b80b41255 100 TIGRFAM TIGR04104 cxxc_20_cxxc: cxxc_20_cxxc protein 3 95 8.6E-26 T 06-07-2017 IPR026369 CxxC-20-CxxC protein GTHT12_RS01270 938e46a7349b66b74eec919b6e029f58 198 Pfam PF09335 SNARE associated Golgi protein 32 156 1.2E-18 T 06-07-2017 IPR032816 SNARE associated Golgi protein GTHT12_RS13285 da4a744b28c00ca4475cc854be6d8327 47 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 41 4.9E-11 T 06-07-2017 IPR012655 Uncharacterised protein YrzI GTHT12_RS15405 a0278caaea826855e99c74b5202e8863 107 Pfam PF14068 Putative membrane protein 8 107 2.6E-43 T 06-07-2017 IPR025917 Putative membrane protein YuiB GTHT12_RS07795 ac4cbcec68761b707bf5808142a374e7 192 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 6 184 9.0E-39 T 06-07-2017 IPR003740 Uncharacterised membrane protein YitT GTHT12_RS09325 4c66d523375913b6dc14393a17821cc2 147 Pfam PF10710 Protein of unknown function (DUF2512) 1 137 1.6E-43 T 06-07-2017 IPR019649 Protein of unknown function DUF2512 GTHT12_RS08620 cb836c16f7e48cbb50ae854699209d78 144 Pfam PF04657 Putative inner membrane exporter, YdcZ 4 140 1.7E-40 T 06-07-2017 IPR006750 Putative inner membrane exporter, YdcZ GTHT12_RS02250 b48af41d79fb79b4d300c6981ffd89f8 243 Pfam PF01925 Sulfite exporter TauE/SafE 7 239 3.2E-23 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 GTHT12_RS17270 95de61ae55bc8f19528771570f16a3a1 433 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 335 418 5.4E-7 T 06-07-2017 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain GTHT12_RS17865 497858cce5c8da31a6211925cbdad254 411 Pfam PF13556 PucR C-terminal helix-turn-helix domain 346 403 3.0E-19 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain GTHT12_RS17865 497858cce5c8da31a6211925cbdad254 411 Gene3D G3DSA:1.10.10.60 351 381 2.5E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 GTHT12_RS18275 633b683cbd1d14619476f007d3588da3 383 SUPERFAMILY SSF53067 214 371 2.23E-12 T 06-07-2017 GTHT12_RS13660 ee13a5727dbd792a059ab3980f2ce94d 172 Pfam PF04093 rod shape-determining protein MreD 4 162 6.5E-28 T 06-07-2017 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 GTHT12_RS13660 ee13a5727dbd792a059ab3980f2ce94d 172 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 7 158 4.1E-32 T 06-07-2017 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 GTHT12_RS06360 1e1f73937c2ec0035cb175477bdb22b0 460 Pfam PF02120 Flagellar hook-length control protein FliK 346 414 1.7E-16 T 06-07-2017 IPR021136 Flagellar hook-length control protein-like, C-terminal GTHT12_RS17455 94cbf342afdbc9dfb4f33881e14143b1 514 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 394 508 4.8E-38 T 06-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17455 94cbf342afdbc9dfb4f33881e14143b1 514 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 445 492 2.0E-21 T 06-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17455 94cbf342afdbc9dfb4f33881e14143b1 514 SUPERFAMILY SSF143243 364 511 2.62E-41 T 06-07-2017 GTHT12_RS04730 08febcf2fe942d44cb2d10b689a5742b 162 Pfam PF03703 Bacterial PH domain 74 148 3.6E-17 T 06-07-2017 IPR005182 Domain of unknown function DUF304 GTHT12_RS11870 0981d6600aee607fc63877741dd45477 148 ProDom PD089241 YPBF MEMBRANE BH1610 TRANSMEMBRANE 12 145 2.0E-48 T 06-07-2017 IPR020210 Uncharacterised protein family, YpbF, transmembrane GTHT12_RS11870 0981d6600aee607fc63877741dd45477 148 Pfam PF10864 Protein of unknown function (DUF2663) 17 146 2.7E-48 T 06-07-2017 IPR020210 Uncharacterised protein family, YpbF, transmembrane GTHT12_RS03020 47717c69c2d3b31928f376f7b0e30074 359 Pfam PF06081 Aromatic acid exporter family member 1 1 143 8.3E-40 T 06-07-2017 IPR010343 Aromatic acid exporter family member 1 GTHT12_RS10460 c62cc0cefdae0fe413d109b576425a06 317 Pfam PF01136 Peptidase family U32 132 223 1.9E-9 T 06-07-2017 IPR001539 Peptidase U32 GO:0006508|GO:0008233 GTHT12_RS16235 dc81869f70ffe9f4c68a6324a4004953 155 SUPERFAMILY SSF140566 1 127 1.31E-19 T 06-07-2017 IPR007809 FlgN-like protein GO:0005515|GO:0044780 GTHT12_RS16235 dc81869f70ffe9f4c68a6324a4004953 155 Pfam PF05130 FlgN protein 1 142 1.0E-25 T 06-07-2017 IPR007809 FlgN-like protein GO:0005515|GO:0044780 GTHT12_RS16235 dc81869f70ffe9f4c68a6324a4004953 155 Gene3D G3DSA:1.20.58.300 3 125 4.6E-14 T 06-07-2017 IPR007809 FlgN-like protein GO:0005515|GO:0044780 GTHT12_RS08590 d49ad3a673dd900353a45a564e25b713 167 Pfam PF06177 QueT transporter 6 151 4.9E-32 T 06-07-2017 IPR010387 Queuosine precursor transporter QueT GO:0005886 GTHT12_RS08590 d49ad3a673dd900353a45a564e25b713 167 PIRSF PIRSF031501 1 159 1.1E-56 T 06-07-2017 IPR010387 Queuosine precursor transporter QueT GO:0005886 GTHT12_RS02830 706c6abf6d586ad96132ec9469dd3885 567 Pfam PF09818 Predicted ATPase of the ABC class 1 448 1.6E-188 T 06-07-2017 IPR019195 ABC transporter, ATPase, putative GTHT12_RS02830 706c6abf6d586ad96132ec9469dd3885 567 SUPERFAMILY SSF52540 239 413 2.54E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase GTHT12_RS07125 95becc89e57e21f6ffd2a91c5c735595 66 Pfam PF12102 Domain of unknown function (DUF3578) 15 66 2.9E-10 T 06-07-2017 IPR021961 Protein of unknown function DUF3578 GTHT12_RS15535 e923436c27fc46a72e0392dc41d7f0fa 324 Pfam PF02653 Branched-chain amino acid transport system / permease component 38 288 7.2E-45 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 GTHT12_RS05745 fc20402cc367b1921a25eaa4c744508b 127 Pfam PF14071 Putative coat protein 10 127 2.2E-43 T 06-07-2017 IPR025953 Putative coat protein YlbD GTHT12_RS16715 cb66a2c245fad8ea306c9230d6bb93b2 66 Pfam PF11755 Protein of unknown function (DUF3311) 6 64 5.3E-23 T 06-07-2017 IPR021741 Protein of unknown function DUF3311 GTHT12_RS18250 af012eed044ca44cc93a984fe84c89be 464 Pfam PF03389 MobA/MobL family 2 44 1.0E-5 T 06-07-2017 IPR005053 MobA/MobL protein GTHT12_RS13825 35b462af832bb3e05a9188376fb921a2 161 ProDom PD104119 YSXD OB2071 ORFY 1 161 7.0E-25 T 06-07-2017 GTHT12_RS17805 6e4e7fdbb189bf1a7a331937343ed794 99 ProDom PD705231 YWDI GROUP-SPECIFIC 1 53 2.0E-20 T 06-07-2017 GTHT12_RS01800 6dae793c935e4970908b21de668d8e96 248 PIRSF PIRSF005054 1 248 6.6E-68 T 06-07-2017 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 GTHT12_RS01800 6dae793c935e4970908b21de668d8e96 248 Pfam PF01881 CRISPR associated protein Cas6 99 243 2.1E-36 T 06-07-2017 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 GTHT12_RS01800 6dae793c935e4970908b21de668d8e96 248 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 46 243 2.0E-37 T 06-07-2017 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 GTHT12_RS02240 398bc70123ca56cb624470f908205234 110 Gene3D G3DSA:3.30.750.24 4 108 2.5E-22 T 06-07-2017 IPR002645 STAS domain GTHT12_RS02240 398bc70123ca56cb624470f908205234 110 SUPERFAMILY SSF52091 5 107 7.06E-21 T 06-07-2017 IPR002645 STAS domain GTHT12_RS02240 398bc70123ca56cb624470f908205234 110 Pfam PF01740 STAS domain 4 103 2.3E-14 T 06-07-2017 IPR002645 STAS domain GTHT12_RS07520 94d2a6553b37350325b5098b28395f63 135 Pfam PF09967 VWA-like domain (DUF2201) 20 134 2.4E-6 T 06-07-2017 IPR018698 VWA-like domain GTHT12_RS08025 00e94ec02d850aaae807566025d547e3 90 Pfam PF10752 Protein of unknown function (DUF2533) 2 84 2.1E-40 T 06-07-2017 IPR019688 Protein of unknown function DUF2533 GTHT12_RS07495 aae008696ea28dc5d20a63645a2c950d 217 Pfam PF04402 Protein of unknown function (DUF541) 16 211 2.2E-40 T 06-07-2017 IPR007497 Protein of unknown function DUF541 GTHT12_RS11200 d772fb9d15f80883fefda3f2d136990a 260 Pfam PF10086 Putative membrane peptidase family (DUF2324) 13 235 4.0E-77 T 06-07-2017 IPR011397 Uncharacterised conserved protein UCP033101 GTHT12_RS11200 d772fb9d15f80883fefda3f2d136990a 260 PIRSF PIRSF033101 2 258 1.3E-75 T 06-07-2017 IPR011397 Uncharacterised conserved protein UCP033101 GTHT12_RS01300 cc316d4d73f91edf4ee49c4fd250b0d4 205 Pfam PF01694 Rhomboid family 54 192 6.6E-33 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 GTHT12_RS01300 cc316d4d73f91edf4ee49c4fd250b0d4 205 Gene3D G3DSA:1.20.1540.10 16 191 2.2E-33 T 06-07-2017 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 GTHT12_RS01300 cc316d4d73f91edf4ee49c4fd250b0d4 205 SUPERFAMILY SSF144091 12 196 1.1E-37 T 06-07-2017 GTHT12_RS18800 b0e52d03e704f52a3e2069257cb671e7 237 ProSitePatterns PS00118 Phospholipase A2 histidine active site. 188 195 - T 06-07-2017 IPR033113 Phospholipase A2, histidine active site KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|Reactome: R-HSA-1482788|Reactome: R-HSA-1482801|Reactome: R-HSA-1482839|Reactome: R-HSA-1482922|Reactome: R-HSA-1482925|Reactome: R-HSA-1483166 GTHT12_RS18800 b0e52d03e704f52a3e2069257cb671e7 237 SUPERFAMILY SSF48619 161 219 4.72E-6 T 06-07-2017 IPR016090 Phospholipase A2 domain KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 GTHT12_RS04475 7663f70c291d99d97866c3b0a25d80f6 151 Pfam PF07098 Protein of unknown function (DUF1360) 44 146 1.7E-37 T 06-07-2017 IPR010773 Mycobacterium phage PG1, Gp7 GTHT12_RS18545 2c9a0d13d95894e8bc0a4f8dc0ac989a 71 Pfam PF11213 Protein of unknown function (DUF3006) 3 69 2.5E-26 T 06-07-2017 IPR021377 Protein of unknown function DUF3006 GTHT12_RS04955 cc12a8439d792c40eeb93ea94d588575 423 Pfam PF12791 Anti-sigma factor N-terminus 7 59 2.7E-10 T 06-07-2017 IPR024449 Anti-sigma factor RsgI, N-terminal GTHT12_RS17685 5f258293a3680e2ad056c42d5e08f21c 143 Pfam PF09148 Domain of unknown function (DUF1934) 17 137 2.4E-26 T 06-07-2017 IPR015231 Protein of unknown function DUF1934 GTHT12_RS17685 5f258293a3680e2ad056c42d5e08f21c 143 Gene3D G3DSA:2.40.128.20 2 141 1.6E-36 T 06-07-2017 IPR012674 Calycin GTHT12_RS17685 5f258293a3680e2ad056c42d5e08f21c 143 SUPERFAMILY SSF50814 2 142 9.93E-34 T 06-07-2017 IPR011038 Calycin-like GTHT12_RS07000 9a7f3600812b1553f13a9186e1e79e40 158 Pfam PF02681 Divergent PAP2 family 2 141 5.2E-44 T 06-07-2017 IPR003832 Acid phosphatase/vanadium-dependent haloperoxidase-related GTHT12_RS10080 da79cd69b389d679e6463f008d85a89e 329 Pfam PF02653 Branched-chain amino acid transport system / permease component 50 316 2.7E-52 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 GTHT12_RS03775 be84f1f66144d13272bcf42e7b1ae6f6 207 Pfam PF09335 SNARE associated Golgi protein 43 161 2.2E-25 T 06-07-2017 IPR032816 SNARE associated Golgi protein GTHT12_RS05155 fc7df7e7722b8ea7dfb052382148b55e 370 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 11 359 8.4E-50 T 06-07-2017 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 GTHT12_RS05155 fc7df7e7722b8ea7dfb052382148b55e 370 Pfam PF03845 Spore germination protein 11 329 3.2E-82 T 06-07-2017 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 GTHT12_RS14670 23d03254a5008c88158231f2c1dfe8bb 89 Pfam PF14165 YtzH-like protein 3 88 2.3E-39 T 06-07-2017 IPR025547 YtzH-like protein GTHT12_RS07255 04f3c5a3c4f358e9a74121581090bcc2 252 Pfam PF12650 Domain of unknown function (DUF3784) 14 105 1.5E-8 T 06-07-2017 IPR017259 Uncharacterised conserved protein UCP037672 GTHT12_RS09580 867d76f56bae1937e1859af8dc22c59f 176 Gene3D G3DSA:1.20.120.520 20 170 3.9E-30 T 06-07-2017 GTHT12_RS09580 867d76f56bae1937e1859af8dc22c59f 176 Pfam PF01814 Hemerythrin HHE cation binding domain 18 158 9.8E-21 T 06-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 GTHT12_RS11800 6f079dd273c86ec3d97214f2342b5fec 59 ProDom PD052359 YPFB 1 55 3.0E-22 T 06-07-2017 GTHT12_RS03455 193862b82d30c625c8c9b7aa921e39b3 67 Pfam PF04328 Protein of unknown function (DUF466) 5 67 1.0E-25 T 06-07-2017 IPR007423 Protein of unknown function DUF466 GTHT12_RS10915 9b5d6d2fc2f92f4d2300876db085336c 372 Pfam PF00487 Fatty acid desaturase 56 299 3.0E-35 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 GTHT12_RS08355 475807a2394a493f606626e8b326fd14 398 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 7 391 2.0E-95 T 06-07-2017 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 GTHT12_RS08355 475807a2394a493f606626e8b326fd14 398 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 227 391 2.7E-35 T 06-07-2017 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 GTHT12_RS06850 b668876343be6710e6c40359a2a50665 201 Pfam PF03458 UPF0126 domain 92 161 1.8E-18 T 06-07-2017 IPR005115 Uncharacterised domain UPF0126 GTHT12_RS06850 b668876343be6710e6c40359a2a50665 201 Pfam PF03458 UPF0126 domain 5 78 9.5E-19 T 06-07-2017 IPR005115 Uncharacterised domain UPF0126 GTHT12_RS01085 d4713c4abee5cc196e49958a2ef806f2 257 SUPERFAMILY SSF53474 2 252 2.11E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS01085 d4713c4abee5cc196e49958a2ef806f2 257 Pfam PF00756 Putative esterase 3 220 1.8E-16 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 GTHT12_RS01085 d4713c4abee5cc196e49958a2ef806f2 257 Gene3D G3DSA:3.40.50.1820 1 253 1.1E-77 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold GTHT12_RS07100 3568d739e1cbeb42ee1c1beaf489d1fd 404 Pfam PF04143 Sulphur transport 63 391 1.3E-73 T 06-07-2017 IPR007272 Sulphur transport domain GTHT12_RS03355 e99cf8805f53c78fca496ec690f631e3 229 Pfam PF04298 Putative neutral zinc metallopeptidase 8 221 7.3E-86 T 06-07-2017 IPR007395 Putative neutral zinc metallopeptidase GTHT12_RS09300 282acd34649645d3bebcceaca3470a1f 190 Pfam PF09911 Uncharacterized protein conserved in bacteria (DUF2140) 3 184 9.0E-55 T 06-07-2017 IPR018672 Protein of unknown function DUF2140 GTHT12_RS17430 5ef5d1774af1b01b1f486f13c25768a1 101 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 101 20.059 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 GTHT12_RS17430 5ef5d1774af1b01b1f486f13c25768a1 101 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 96 1.2E-25 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 GTHT12_RS04040 c3a44c0664f4e239f46bf91fcfe41827 100 SUPERFAMILY SSF117916 4 97 1.37E-31 T 06-07-2017 GTHT12_RS04040 c3a44c0664f4e239f46bf91fcfe41827 100 Pfam PF01883 Domain of unknown function DUF59 10 77 2.6E-21 T 06-07-2017 IPR002744 Domain of unknown function DUF59 GTHT12_RS02775 90a7d123fe43867f50b43939672de7a7 172 Pfam PF04892 VanZ like family 13 150 1.9E-22 T 06-07-2017 IPR006976 VanZ-like GTHT12_RS15690 335ec97f156735114672dd175a0d4c18 111 Pfam PF07875 Coat F domain 20 82 5.6E-24 T 06-07-2017 IPR012851 Spore coat protein CotF-like GTHT12_RS04425 53bb5c86b0fa1f5736f98f652bc0adfe 135 Pfam PF14153 Spore coat protein CotO 40 133 1.0E-11 T 06-07-2017 IPR025439 Spore coat protein CotO GTHT12_RS14390 258b7b414425d3f0e74a4cb3a6707c63 190 Pfam PF06271 RDD family 57 183 5.1E-28 T 06-07-2017 IPR010432 RDD GTHT12_RS12545 66433c99160ed1d1b5af285b99fa2e56 134 Pfam PF03780 Asp23 family, cell envelope-related function 16 120 2.1E-38 T 06-07-2017 IPR005531 Alkaline shock protein Asp23 GTHT12_RS11880 1a7c7a3bc336e159b893bf792a6a9faa 195 Pfam PF02517 CAAX protease self-immunity 97 179 8.7E-13 T 06-07-2017 IPR003675 CAAX amino terminal protease GO:0016020 GTHT12_RS03830 e455d8ac7508c29499fa4181499c3665 73 Pfam PF10676 Spore germination protein gerPA/gerPF 1 72 1.2E-30 T 06-07-2017 IPR019618 Spore germination protein GerPA/GerPF GTHT12_RS05120 59f1ce52a2120480260c0eb1e5928a6c 341 Pfam PF12698 ABC-2 family transporter protein 18 332 7.3E-37 T 06-07-2017 GTHT12_RS18580 f116b4921bce2371d807ba7e9af8ef6e 330 Pfam PF08401 Domain of unknown function (DUF1738) 46 132 1.5E-5 T 06-07-2017 IPR013610 Domain of unknown function DUF1738 GTHT12_RS15510 0324b3ec21693fb3e6fd47e7ba8037dc 228 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 14 187 1.6E-30 T 06-07-2017 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like GTHT12_RS17465 83d08c5ec1fcca8967caddbf7bd67a29 122 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 26 121 2.2E-37 T 06-07-2017 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 GTHT12_RS17465 83d08c5ec1fcca8967caddbf7bd67a29 122 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 5 122 18.912 T 06-07-2017 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 GTHT12_RS18025 a2ed05cf332cdf8cbcd4353474c84958 292 Pfam PF13612 Transposase DDE domain 111 267 1.4E-28 T 06-07-2017 IPR025668 Transposase DDE domain GTHT12_RS02255 97c15ac885983b0b95187bd84eb746b5 137 Pfam PF06271 RDD family 6 127 2.0E-18 T 06-07-2017 IPR010432 RDD GTHT12_RS01865 f4c94a839f0fe107d16db662c123e47e 217 Pfam PF04012 PspA/IM30 family 2 203 4.0E-35 T 06-07-2017 IPR007157 PspA/IM30 GTHT12_RS08315 b8ce9f8ee7c6d6c95e9f1a381668ffce 511 PIRSF PIRSF005690 21 511 1.7E-138 T 06-07-2017 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 GTHT12_RS08315 b8ce9f8ee7c6d6c95e9f1a381668ffce 511 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 29 496 2.1E-140 T 06-07-2017 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 GTHT12_RS18435 5799396b577f88341fb751508b073c3f 92 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 25 88 5.6E-11 T 06-07-2017 IPR008792 Coenzyme PQQ synthesis D GTHT12_RS16060 8ab86faa031cd4f4516f295a03124cb0 73 Pfam PF09964 Uncharacterized protein conserved in bacteria (DUF2198) 2 73 1.8E-31 T 06-07-2017 IPR019242 Protein of unknown function DUF2198 GTHT12_RS09715 f5e3ff23b0cff7ea70b427b776697342 319 Pfam PF01758 Sodium Bile acid symporter family 42 220 3.5E-44 T 06-07-2017 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 GTHT12_RS05185 32108c3b31c6b7eb9727bddad5f6274f 59 Pfam PF09953 Uncharacterized protein conserved in bacteria (DUF2187) 3 58 5.9E-32 T 06-07-2017 IPR018690 Protein of unknown function DUF2187 GTHT12_RS05890 fcba3e2f56c0f56175b34f1a768e06a1 234 Pfam PF05949 Bacterial protein of unknown function (DUF881) 94 229 1.2E-34 T 06-07-2017 IPR010273 Protein of unknown function DUF881 GTHT12_RS08765 77757721ab05ebcfc86c92ef7dd9eaa1 616 Gene3D G3DSA:1.20.5.170 67 106 2.2E-4 T 06-07-2017 GTHT12_RS06400 886ffedd6a3ebd22131f503f3f0b7c92 217 Pfam PF04347 Flagellar biosynthesis protein, FliO 85 191 6.4E-12 T 06-07-2017 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 GTHT12_RS16805 5ceb7ff1d9141119430173453aa10d4f 125 Pfam PF04343 Protein of unknown function, DUF488 13 121 6.0E-31 T 06-07-2017 IPR007438 Protein of unknown function DUF488 GTHT12_RS10710 5a4e30b799a5de7e96ad378d551b7aef 330 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 285 6.2E-28 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 GTHT12_RS16170 21ca3600a915402f398543e9b9e2ad40 210 Pfam PF14487 Domain of unknown function (DUF4433) 8 210 5.3E-65 T 06-07-2017 IPR029494 Domain of unknown function DUF4433 GTHT12_RS10000 acacb05fa12c6730ac8852d8c294cc49 407 Pfam PF02653 Branched-chain amino acid transport system / permease component 61 396 9.1E-44 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 GTHT12_RS01470 3e89ed1715e4fc9a9a8b1270cc9390a0 59 Pfam PF14146 Domain of unknown function (DUF4305) 18 54 3.5E-17 T 06-07-2017 IPR025426 Protein of unknown function DUF4305 GTHT12_RS12470 9556b8aa85e5924b51087940bf1fe2fc 50 Pfam PF14174 YycC-like protein 1 48 6.4E-24 T 06-07-2017 IPR025550 YycC-like protein GTHT12_RS16035 cd51850cd8bdbe78f4c2a0b1358613d1 120 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 3 106 1.6E-25 T 06-07-2017 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV GTHT12_RS01510 7e8ad557d35604ab050f59727321be0d 407 Pfam PF01566 Natural resistance-associated macrophage protein 27 373 1.1E-32 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 GTHT12_RS05725 5ab368e112313a63d2e7b3164d72b8ff 97 Pfam PF03780 Asp23 family, cell envelope-related function 37 92 1.6E-7 T 06-07-2017 IPR005531 Alkaline shock protein Asp23 GTHT12_RS02630 e283806065629d0020b9ad59780483d3 79 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 3 78 3.4E-12 T 06-07-2017 IPR024962 YukD-like GTHT12_RS11105 4f8ef25752763a853085c748d5df7983 108 SUPERFAMILY SSF101386 24 84 8.04E-7 T 06-07-2017 GTHT12_RS02980 1d2521ed789808ba81f84a779e3d47c0 83 Pfam PF14182 YgaB-like protein 26 80 1.5E-10 T 06-07-2017 IPR025572 YgaB-like protein