locus-tag	class	description
GsYM18_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GsYM18_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GsYM18_RS00020	COG0187	DNA topoisomerase II activity
GsYM18_RS00035	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GsYM18_RS00040	COG5002	protein histidine kinase activity
GsYM18_RS00045	COG5002	protein histidine kinase activity
GsYM18_RS00050	COG4251	negative regulation of phosphorylation
GsYM18_RS00055	COG2205	protein histidine kinase activity
GsYM18_RS00065	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GsYM18_RS00075	COG0484	heat shock protein binding
GsYM18_RS00080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GsYM18_RS00085	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GsYM18_RS00095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GsYM18_RS00105	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GsYM18_RS00110	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GsYM18_RS00115	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GsYM18_RS00130	COG0823	Involved in the tonB-independent uptake of proteins
GsYM18_RS00150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GsYM18_RS00155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GsYM18_RS00160	COG1420	regulation of RNA biosynthetic process
GsYM18_RS00165	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GsYM18_RS00170	COG0443	Heat shock 70 kDa protein
GsYM18_RS00175	COG0484	heat shock protein binding
GsYM18_RS00180	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GsYM18_RS00190	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GsYM18_RS00215	COG0590	tRNA wobble adenosine to inosine editing
GsYM18_RS00235	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
GsYM18_RS00250	COG0732	type I restriction modification DNA specificity domain
GsYM18_RS00290	COG0288	reversible hydration of carbon dioxide
GsYM18_RS00320	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GsYM18_RS00345	COG1396	sequence-specific DNA binding
GsYM18_RS00360	COG0564	pseudouridine synthase activity
GsYM18_RS00375	COG0543	2 iron, 2 sulfur cluster binding
GsYM18_RS00400	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
GsYM18_RS00415	COG1132	(ABC) transporter
GsYM18_RS00430	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GsYM18_RS00435	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GsYM18_RS00440	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GsYM18_RS00445	COG0674	pyruvate-flavodoxin oxidoreductase activity
GsYM18_RS00445	COG1013	pyruvate-flavodoxin oxidoreductase activity
GsYM18_RS00445	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GsYM18_RS00445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GsYM18_RS00455	COG1100	Small GTP-binding protein
GsYM18_RS00460	COG1132	(ABC) transporter
GsYM18_RS00475	COG0784	Response regulator, receiver
GsYM18_RS00485	COG1192	Involved in chromosome partitioning
GsYM18_RS00490	COG1475	DNA binding
GsYM18_RS00495	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GsYM18_RS00500	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GsYM18_RS00505	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GsYM18_RS00510	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GsYM18_RS00515	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GsYM18_RS00520	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GsYM18_RS00525	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GsYM18_RS00530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GsYM18_RS00535	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GsYM18_RS00540	COG0436	Aminotransferase
GsYM18_RS00555	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GsYM18_RS00560	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
GsYM18_RS00565	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GsYM18_RS00575	COG1040	competence protein
GsYM18_RS00585	COG0348	domain, Protein
GsYM18_RS00590	COG0037	tRNA processing
GsYM18_RS00595	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GsYM18_RS00600	COG0242	peptide deformylase activity
GsYM18_RS00605	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GsYM18_RS00625	COG1234	tRNA 3'-trailer cleavage
GsYM18_RS00630	COG0113	porphobilinogen synthase activity
GsYM18_RS00635	COG2259	Doxx family
GsYM18_RS00645	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GsYM18_RS00655	COG1691	(AIR) carboxylase
GsYM18_RS00660	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
GsYM18_RS00665	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GsYM18_RS00670	COG1058	Belongs to the CinA family
GsYM18_RS00670	COG1546	Belongs to the CinA family
GsYM18_RS00675	COG5002	protein histidine kinase activity
GsYM18_RS00680	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GsYM18_RS00690	COG2137	regulation of response to DNA damage stimulus
GsYM18_RS00695	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GsYM18_RS00700	COG5002	protein histidine kinase activity
GsYM18_RS00705	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GsYM18_RS00710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GsYM18_RS00715	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GsYM18_RS00720	COG0137	argininosuccinate synthase activity
GsYM18_RS00735	COG0165	Argininosuccinate lyase
GsYM18_RS00755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GsYM18_RS00760	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GsYM18_RS00765	COG0436	Aminotransferase
GsYM18_RS00795	COG3177	Filamentation induced by cAMP protein fic
GsYM18_RS00800	COG0488	(ABC) transporter
GsYM18_RS00810	COG1671	Belongs to the UPF0178 family
GsYM18_RS00820	COG0789	Transcriptional regulator
GsYM18_RS00830	COG0427	acetyl-CoA hydrolase
GsYM18_RS00845	COG3153	acetyltransferase
GsYM18_RS00850	COG1733	regulation of RNA biosynthetic process
GsYM18_RS00855	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GsYM18_RS00860	COG1451	nucleotide metabolic process
GsYM18_RS00865	COG3034	peptidoglycan biosynthetic process
GsYM18_RS00875	COG1376	ErfK ybiS ycfS ynhG family protein
GsYM18_RS00880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GsYM18_RS00890	COG1881	PFAM PEBP family protein
GsYM18_RS00915	COG0513	Belongs to the DEAD box helicase family
GsYM18_RS00925	COG1278	Cold shock
GsYM18_RS00950	COG4221	oxidoreductase activity
GsYM18_RS00970	COG2010	Cytochrome c
GsYM18_RS00970	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GsYM18_RS00975	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GsYM18_RS00975	COG3608	succinylglutamate desuccinylase aspartoacylase
GsYM18_RS00985	COG1032	radical SAM domain protein
GsYM18_RS00995	COG0428	transporter
GsYM18_RS01000	COG1278	Cold shock
GsYM18_RS01020	COG4120	Belongs to the binding-protein-dependent transport system permease family
GsYM18_RS01025	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GsYM18_RS01040	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GsYM18_RS01050	COG0778	Nitroreductase
GsYM18_RS01065	COG1845	cytochrome c oxidase, subunit III
GsYM18_RS01075	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GsYM18_RS01080	COG0109	protoheme IX farnesyltransferase activity
GsYM18_RS01105	COG1047	Peptidyl-prolyl cis-trans
GsYM18_RS01110	COG0318	PFAM AMP-dependent synthetase and ligase
GsYM18_RS01130	COG3132	Protein of unknown function, DUF480
GsYM18_RS01135	COG2116	formate transmembrane transporter activity
GsYM18_RS01140	COG2183	response to ionizing radiation
GsYM18_RS01155	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GsYM18_RS01160	COG0824	Thioesterase
GsYM18_RS01170	COG1032	radical SAM domain protein
GsYM18_RS01175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GsYM18_RS01205	COG1032	radical SAM domain protein
GsYM18_RS01210	COG0697	spore germination
GsYM18_RS01240	COG2197	response regulator
GsYM18_RS01245	COG4251	negative regulation of phosphorylation
GsYM18_RS01275	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GsYM18_RS01275	COG4651	solute:proton antiporter activity
GsYM18_RS01285	COG2814	Major facilitator Superfamily
GsYM18_RS01295	COG0583	DNA-binding transcription factor activity
GsYM18_RS01310	COG2188	Transcriptional regulator
GsYM18_RS01315	COG0730	response to heat
GsYM18_RS01325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GsYM18_RS01330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GsYM18_RS01340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GsYM18_RS01390	COG4191	Histidine kinase
GsYM18_RS01395	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GsYM18_RS01400	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GsYM18_RS01425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GsYM18_RS01440	COG2201	protein-glutamate methylesterase activity
GsYM18_RS01455	COG0784	Response regulator, receiver
GsYM18_RS01455	COG0643	Histidine kinase
GsYM18_RS01455	COG2198	Histidine kinase
GsYM18_RS01460	COG0835	chemotaxis
GsYM18_RS01470	COG0741	lytic transglycosylase activity
GsYM18_RS01480	COG5002	protein histidine kinase activity
GsYM18_RS01485	COG0308	aminopeptidase N
GsYM18_RS01505	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GsYM18_RS01510	COG0298	carbon dioxide binding
GsYM18_RS01540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GsYM18_RS01560	COG0501	Belongs to the peptidase M48B family
GsYM18_RS01595	COG4970	Tfp pilus assembly protein FimT
GsYM18_RS01625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GsYM18_RS01630	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GsYM18_RS01635	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GsYM18_RS01640	COG0356	it plays a direct role in the translocation of protons across the membrane
GsYM18_RS01655	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GsYM18_RS01660	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GsYM18_RS01665	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GsYM18_RS01670	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GsYM18_RS01675	COG0649	NAD binding
GsYM18_RS01695	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GsYM18_RS01700	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GsYM18_RS01705	COG0839	Belongs to the complex I subunit 6 family
GsYM18_RS01710	COG0713	ATP synthesis coupled electron transport
GsYM18_RS01725	COG1007	ATP synthesis coupled electron transport
GsYM18_RS01730	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GsYM18_RS01735	COG1238	metal cluster binding
GsYM18_RS01750	COG4251	negative regulation of phosphorylation
GsYM18_RS01755	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GsYM18_RS01785	COG1199	ATP-dependent helicase activity
GsYM18_RS01805	COG1242	4 iron, 4 sulfur cluster binding
GsYM18_RS01815	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GsYM18_RS01830	COG2204	response regulator
GsYM18_RS01835	COG3852	Histidine kinase
GsYM18_RS01840	COG0375	protein maturation
GsYM18_RS01845	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GsYM18_RS01850	COG0509	glycine decarboxylation via glycine cleavage system
GsYM18_RS01860	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GsYM18_RS01865	COG0095	Lipoate-protein ligase
GsYM18_RS01870	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GsYM18_RS01885	COG1047	Peptidyl-prolyl cis-trans
GsYM18_RS01895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GsYM18_RS01895	COG3320	Male sterility
GsYM18_RS01900	COG2003	Belongs to the UPF0758 family
GsYM18_RS01905	COG1968	undecaprenyl-diphosphatase activity
GsYM18_RS01910	COG1392	Phosphate transport regulator
GsYM18_RS01915	COG0306	phosphate transporter
GsYM18_RS01925	COG1538	Outer membrane efflux protein
GsYM18_RS01930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GsYM18_RS01965	COG0840	transmembrane signaling receptor activity
GsYM18_RS01975	COG2703	oxygen carrier activity
GsYM18_RS01980	COG0745	RESPONSE REGULATOR receiver
GsYM18_RS02000	COG1815	bacterial-type flagellum-dependent cell motility
GsYM18_RS02010	COG1677	Flagellar hook-basal body complex protein FliE
GsYM18_RS02020	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GsYM18_RS02030	COG1157	protein secretion by the type III secretion system
GsYM18_RS02050	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GsYM18_RS02085	COG1338	Plays a role in the flagellum-specific transport system
GsYM18_RS02090	COG1987	bacterial-type flagellum assembly
GsYM18_RS02100	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GsYM18_RS02140	COG0482	sulfurtransferase activity
GsYM18_RS02160	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GsYM18_RS02170	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GsYM18_RS02175	COG0163	prenyltransferase activity
GsYM18_RS02180	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GsYM18_RS02185	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GsYM18_RS02200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GsYM18_RS02205	COG2264	protein methyltransferase activity
GsYM18_RS02215	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GsYM18_RS02220	COG0745	RESPONSE REGULATOR receiver
GsYM18_RS02225	COG5002	protein histidine kinase activity
GsYM18_RS02230	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GsYM18_RS02235	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GsYM18_RS02260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GsYM18_RS02265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GsYM18_RS02275	COG1028	Short-chain dehydrogenase reductase Sdr
GsYM18_RS02280	COG0501	Belongs to the peptidase M48B family
GsYM18_RS02295	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GsYM18_RS02325	COG2204	response regulator
GsYM18_RS02330	COG4191	Histidine kinase
GsYM18_RS02350	COG2205	protein histidine kinase activity
GsYM18_RS02370	COG1027	Aspartate ammonia-lyase
GsYM18_RS02375	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GsYM18_RS02385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GsYM18_RS02390	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GsYM18_RS02395	COG1469	GTP cyclohydrolase I activity
GsYM18_RS02405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GsYM18_RS02415	COG0492	ferredoxin-NADP+ reductase activity
GsYM18_RS02420	COG0606	chelatase, subunit chli
GsYM18_RS02425	COG0427	acetyl-CoA hydrolase
GsYM18_RS02430	COG0513	Belongs to the DEAD box helicase family
GsYM18_RS02435	COG4974	Belongs to the 'phage' integrase family
GsYM18_RS02440	COG1252	NADH dehydrogenase
GsYM18_RS02445	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
GsYM18_RS02450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GsYM18_RS02455	COG1136	(ABC) transporter
GsYM18_RS02460	COG0577	efflux transmembrane transporter activity
GsYM18_RS02460	COG1136	(ABC) transporter
GsYM18_RS02470	COG0739	heme binding
GsYM18_RS02475	COG1217	gtp-binding protein TYPA
GsYM18_RS02490	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GsYM18_RS02495	COG1993	acr, cog1993
GsYM18_RS02500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GsYM18_RS02510	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GsYM18_RS02515	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GsYM18_RS02540	COG0237	dephospho-CoA kinase activity
GsYM18_RS02545	COG1414	Transcriptional regulator
GsYM18_RS02565	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GsYM18_RS02575	COG0585	pseudouridine synthase activity
GsYM18_RS02580	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GsYM18_RS02585	COG0513	Belongs to the DEAD box helicase family
GsYM18_RS02600	COG1490	D-aminoacyl-tRNA deacylase activity
GsYM18_RS02620	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GsYM18_RS02650	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GsYM18_RS02655	COG1606	tRNA processing
GsYM18_RS02665	COG0071	Belongs to the small heat shock protein (HSP20) family
GsYM18_RS02685	COG2199	diguanylate cyclase activity
GsYM18_RS02705	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GsYM18_RS02710	COG1193	negative regulation of DNA recombination
GsYM18_RS02715	COG1032	radical SAM domain protein
GsYM18_RS02720	COG2226	methyltransferase
GsYM18_RS02745	COG1024	Enoyl-CoA hydratase
GsYM18_RS02760	COG0277	FAD linked oxidase domain protein
GsYM18_RS02805	COG2818	Glycosylase
GsYM18_RS02815	COG1335	isochorismatase
GsYM18_RS02840	COG0697	spore germination
GsYM18_RS02845	COG1966	Carbon starvation protein
GsYM18_RS02855	COG1381	Involved in DNA repair and RecF pathway recombination
GsYM18_RS02860	COG0752	glycyl-tRNA synthetase alpha subunit
GsYM18_RS02865	COG0751	glycine-tRNA ligase activity
GsYM18_RS02870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GsYM18_RS02870	COG0574	Belongs to the PEP-utilizing enzyme family
GsYM18_RS02875	COG1278	Cold shock
GsYM18_RS02895	COG0179	Fumarylacetoacetate (FAA) hydrolase
GsYM18_RS02900	COG1242	4 iron, 4 sulfur cluster binding
GsYM18_RS02905	COG0352	thiamine-phosphate diphosphorylase activity
GsYM18_RS02910	COG2022	thiamine diphosphate biosynthetic process
GsYM18_RS02935	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
GsYM18_RS02960	COG2204	response regulator
GsYM18_RS02975	COG3228	Belongs to the MtfA family
GsYM18_RS02990	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GsYM18_RS02995	COG0351	phosphomethylpyrimidine kinase
GsYM18_RS02995	COG0352	thiamine-phosphate diphosphorylase activity
GsYM18_RS03000	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GsYM18_RS03015	COG0138	bifunctional purine biosynthesis protein purh
GsYM18_RS03020	COG0151	Belongs to the GarS family
GsYM18_RS03035	COG1333	cytochrome c biogenesis protein
GsYM18_RS03040	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GsYM18_RS03080	COG0463	Glycosyl transferase, family 2
GsYM18_RS03085	COG0297	glycogen (starch) synthase activity
GsYM18_RS03100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GsYM18_RS03115	COG2226	methyltransferase
GsYM18_RS03120	COG1216	Glycosyl transferase, family 2
GsYM18_RS03125	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GsYM18_RS03145	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GsYM18_RS03165	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GsYM18_RS03170	COG0228	four-way junction DNA binding
GsYM18_RS03180	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GsYM18_RS03185	COG0336	Belongs to the RNA methyltransferase TrmD family
GsYM18_RS03190	COG4752	Belongs to the RNA methyltransferase TrmD family
GsYM18_RS03195	COG0335	large ribosomal subunit rRNA binding
GsYM18_RS03200	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GsYM18_RS03205	COG0792	nuclease activity
GsYM18_RS03210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GsYM18_RS03210	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GsYM18_RS03220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GsYM18_RS03250	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GsYM18_RS03255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GsYM18_RS03260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GsYM18_RS03270	COG0542	response to heat
GsYM18_RS03280	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GsYM18_RS03290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GsYM18_RS03295	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GsYM18_RS03300	COG0193	aminoacyl-tRNA hydrolase activity
GsYM18_RS03305	COG0012	GTP binding
GsYM18_RS03310	COG0360	Binds together with S18 to 16S ribosomal RNA
GsYM18_RS03315	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GsYM18_RS03325	COG0359	binds to the 23S rRNA
GsYM18_RS03335	COG0564	pseudouridine synthase activity
GsYM18_RS03350	COG1151	hydroxylamine reductase activity
GsYM18_RS03365	COG0577	efflux transmembrane transporter activity
GsYM18_RS03365	COG1136	(ABC) transporter
GsYM18_RS03370	COG1136	(ABC) transporter
GsYM18_RS03375	COG0500	methyltransferase
GsYM18_RS03405	COG0835	chemotaxis
GsYM18_RS03420	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GsYM18_RS03425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GsYM18_RS03430	COG1657	PFAM Prenyltransferase squalene oxidase
GsYM18_RS03440	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GsYM18_RS03445	COG0023	Translation Initiation Factor
GsYM18_RS03455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GsYM18_RS03460	COG4251	negative regulation of phosphorylation
GsYM18_RS03495	COG2208	phosphoserine phosphatase activity
GsYM18_RS03520	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GsYM18_RS03520	COG1333	cytochrome c biogenesis protein
GsYM18_RS03590	COG2267	carboxylic ester hydrolase activity
GsYM18_RS03630	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GsYM18_RS03650	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GsYM18_RS03655	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GsYM18_RS03660	COG1077	Cell shape determining protein MreB Mrl
GsYM18_RS03665	COG0651	ATP synthesis coupled electron transport
GsYM18_RS03685	COG0651	ATP synthesis coupled electron transport
GsYM18_RS03700	COG0651	ATP synthesis coupled electron transport
GsYM18_RS03705	COG3261	NADH dehydrogenase
GsYM18_RS03705	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
GsYM18_RS03710	COG3260	NADH ubiquinone oxidoreductase 20
GsYM18_RS03735	COG1794	racemase activity, acting on amino acids and derivatives
GsYM18_RS03785	COG1811	Na channel or pump
GsYM18_RS03790	COG3177	Filamentation induced by cAMP protein fic
GsYM18_RS03840	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GsYM18_RS03850	COG2962	Rard protein
GsYM18_RS03860	COG1309	transcriptional regulator
GsYM18_RS03865	COG0604	alcohol dehydrogenase
GsYM18_RS03875	COG2814	Major facilitator Superfamily
GsYM18_RS03885	COG4191	Histidine kinase
GsYM18_RS03890	COG2204	response regulator
GsYM18_RS03900	COG3064	Membrane
GsYM18_RS03900	COG0437	4 iron, 4 sulfur cluster binding
GsYM18_RS03905	COG5557	Pfam Polysulphide reductase, NrfD
GsYM18_RS03910	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GsYM18_RS03915	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GsYM18_RS03925	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
GsYM18_RS03930	COG0437	4 iron, 4 sulfur cluster binding
GsYM18_RS03935	COG5557	Pfam Polysulphide reductase, NrfD
GsYM18_RS03940	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
GsYM18_RS03945	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GsYM18_RS03950	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GsYM18_RS03960	COG0745	RESPONSE REGULATOR receiver
GsYM18_RS03985	COG0446	pyridine nucleotide-disulphide oxidoreductase
GsYM18_RS04000	COG1607	acyl-coa hydrolase
GsYM18_RS04005	COG2095	MarC family integral membrane protein
GsYM18_RS04010	COG1126	abc transporter atp-binding protein
GsYM18_RS04015	COG0765	amino acid transport
GsYM18_RS04035	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GsYM18_RS04035	COG0574	Belongs to the PEP-utilizing enzyme family
GsYM18_RS04040	COG0655	NAD(P)H dehydrogenase (quinone) activity
GsYM18_RS04045	COG3030	protein affecting phage T7 exclusion by the F plasmid
GsYM18_RS04060	COG3706	GGDEF domain
GsYM18_RS04065	COG0288	reversible hydration of carbon dioxide
GsYM18_RS04075	COG2204	response regulator
GsYM18_RS04080	COG5000	phosphorelay sensor kinase activity
GsYM18_RS04100	COG1127	ABC transporter
GsYM18_RS04105	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GsYM18_RS04110	COG1012	belongs to the aldehyde dehydrogenase family
GsYM18_RS04125	COG0616	signal peptide processing
GsYM18_RS04140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GsYM18_RS04150	COG1741	Belongs to the pirin family
GsYM18_RS04210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GsYM18_RS04225	COG2204	response regulator
GsYM18_RS04240	COG0490	domain, Protein
GsYM18_RS04240	COG0471	metal ion transport
GsYM18_RS04260	COG1773	rubredoxin
GsYM18_RS04270	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GsYM18_RS04280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GsYM18_RS04295	COG1253	flavin adenine dinucleotide binding
GsYM18_RS04300	COG0628	permease
GsYM18_RS04325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GsYM18_RS04340	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GsYM18_RS04350	COG1872	DUF167
GsYM18_RS04365	COG2226	methyltransferase
GsYM18_RS04375	COG0791	NLP P60 protein
GsYM18_RS04380	COG0494	nUDIX hydrolase
GsYM18_RS04405	COG1597	lipid kinase activity
GsYM18_RS04410	COG0745	RESPONSE REGULATOR receiver
GsYM18_RS04420	COG0835	chemotaxis
GsYM18_RS04420	COG0784	Response regulator, receiver
GsYM18_RS04425	COG0243	molybdopterin cofactor binding
GsYM18_RS04430	COG4251	negative regulation of phosphorylation
GsYM18_RS04440	COG4206	TonB-dependent receptor
GsYM18_RS04455	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GsYM18_RS04465	COG1254	Belongs to the acylphosphatase family
GsYM18_RS04470	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GsYM18_RS04475	COG1404	Belongs to the peptidase S8 family
GsYM18_RS04485	COG0450	alkyl hydroperoxide reductase
GsYM18_RS04490	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GsYM18_RS04495	COG3706	GGDEF domain
GsYM18_RS04505	COG0312	modulator of DNA gyrase
GsYM18_RS04515	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GsYM18_RS04520	COG0514	ATP-dependent DNA helicase (RecQ)
GsYM18_RS04525	COG4399	Belongs to the UPF0754 family
GsYM18_RS04540	COG0745	RESPONSE REGULATOR receiver
GsYM18_RS04550	COG2205	protein histidine kinase activity
GsYM18_RS04570	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GsYM18_RS04575	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GsYM18_RS04590	COG2414	aldehyde ferredoxin oxidoreductase
GsYM18_RS04595	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GsYM18_RS04605	COG0488	(ABC) transporter
GsYM18_RS04610	COG0513	Belongs to the DEAD box helicase family
GsYM18_RS04625	COG2832	Protein of unknown function (DUF454)
GsYM18_RS04630	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
GsYM18_RS04645	COG1530	ribonuclease E activity
GsYM18_RS04650	COG0488	(ABC) transporter
GsYM18_RS04655	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GsYM18_RS04660	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GsYM18_RS04665	COG1127	ABC transporter
GsYM18_RS04675	COG0612	Peptidase, M16
GsYM18_RS04705	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GsYM18_RS04715	COG0840	transmembrane signaling receptor activity
GsYM18_RS04720	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GsYM18_RS04725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GsYM18_RS04735	COG0347	Belongs to the P(II) protein family
GsYM18_RS04740	COG0004	ammonium transporteR
GsYM18_RS04745	COG4191	Histidine kinase
GsYM18_RS04750	COG0483	inositol monophosphate 1-phosphatase activity
GsYM18_RS04760	COG0626	cystathionine gamma-synthase activity
GsYM18_RS04765	COG0626	cystathionine gamma-synthase activity
GsYM18_RS04775	COG1136	(ABC) transporter
GsYM18_RS04820	COG3852	Histidine kinase
GsYM18_RS04825	COG2204	response regulator
GsYM18_RS04850	COG0793	Belongs to the peptidase S41A family
GsYM18_RS04865	COG1222	aaa ATPase
GsYM18_RS04950	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GsYM18_RS04950	COG3743	rRNA binding
GsYM18_RS04955	COG0438	transferase activity, transferring glycosyl groups
GsYM18_RS04970	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GsYM18_RS04970	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GsYM18_RS04980	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GsYM18_RS04985	COG0305	Participates in initiation and elongation during chromosome replication
GsYM18_RS04990	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GsYM18_RS05005	COG1335	isochorismatase
GsYM18_RS05015	COG3852	Histidine kinase
GsYM18_RS05020	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GsYM18_RS05030	COG2199	diguanylate cyclase activity
GsYM18_RS05030	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GsYM18_RS05035	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GsYM18_RS05060	COG1360	Flagellar Motor Protein
GsYM18_RS05075	COG2985	domain, Protein
GsYM18_RS05075	COG0569	domain protein
GsYM18_RS05080	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GsYM18_RS05090	COG2252	PERMEase
GsYM18_RS05100	COG0297	glycogen (starch) synthase activity
GsYM18_RS05120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GsYM18_RS05135	COG0840	transmembrane signaling receptor activity
GsYM18_RS05140	COG0840	transmembrane signaling receptor activity
GsYM18_RS05150	COG3290	protein histidine kinase activity
GsYM18_RS05150	COG0840	transmembrane signaling receptor activity
GsYM18_RS05155	COG0840	transmembrane signaling receptor activity
GsYM18_RS05165	COG2205	protein histidine kinase activity
GsYM18_RS05180	COG2204	response regulator
GsYM18_RS05185	COG0840	transmembrane signaling receptor activity
GsYM18_RS05190	COG2703	oxygen carrier activity
GsYM18_RS05195	COG4251	negative regulation of phosphorylation
GsYM18_RS05220	COG3012	SEC-C Motif Domain Protein
GsYM18_RS05225	COG1234	tRNA 3'-trailer cleavage
GsYM18_RS05230	COG0642	Histidine kinase
GsYM18_RS05255	COG2391	methyltransferase activity
GsYM18_RS05260	COG0432	Pfam Uncharacterised protein family UPF0047
GsYM18_RS05270	COG0045	succinate-CoA ligase (ADP-forming) activity
GsYM18_RS05275	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GsYM18_RS05285	COG0436	Aminotransferase
GsYM18_RS05320	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GsYM18_RS05330	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GsYM18_RS05350	COG0217	transcriptional regulatory protein
GsYM18_RS05355	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GsYM18_RS05360	COG0632	four-way junction helicase activity
GsYM18_RS05365	COG2255	four-way junction helicase activity
GsYM18_RS05370	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GsYM18_RS05385	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GsYM18_RS05420	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GsYM18_RS05450	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GsYM18_RS05455	COG0573	inorganic phosphate transmembrane transporter activity
GsYM18_RS05460	COG0573	inorganic phosphate transmembrane transporter activity
GsYM18_RS05465	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GsYM18_RS05475	COG5002	protein histidine kinase activity
GsYM18_RS05480	COG0745	RESPONSE REGULATOR receiver
GsYM18_RS05485	COG0318	PFAM AMP-dependent synthetase and ligase
GsYM18_RS05495	COG0006	proline dipeptidase activity
GsYM18_RS05510	COG1012	belongs to the aldehyde dehydrogenase family
GsYM18_RS05520	COG0105	UTP biosynthetic process
GsYM18_RS05525	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GsYM18_RS05530	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GsYM18_RS05555	COG2204	response regulator
GsYM18_RS05560	COG0589	response to stress
GsYM18_RS05565	COG4191	Histidine kinase
GsYM18_RS05575	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GsYM18_RS05580	COG3481	metal-dependent phosphohydrolase, HD sub domain
GsYM18_RS05585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GsYM18_RS05590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GsYM18_RS05600	COG1573	uracil-dna glycosylase
GsYM18_RS05615	COG2204	response regulator
GsYM18_RS05620	COG1196	nuclear chromosome segregation
GsYM18_RS05630	COG0552	protein localization to endoplasmic reticulum
GsYM18_RS05650	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GsYM18_RS05655	COG1418	mRNA catabolic process
GsYM18_RS05660	COG1692	metallophosphoesterase
GsYM18_RS05665	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GsYM18_RS05700	COG0840	transmembrane signaling receptor activity
GsYM18_RS05700	COG0840	transmembrane signaling receptor activity
GsYM18_RS05705	COG0840	transmembrane signaling receptor activity
GsYM18_RS05710	COG0835	chemotaxis
GsYM18_RS05720	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GsYM18_RS05725	COG2201	protein-glutamate methylesterase activity
GsYM18_RS05740	COG4191	Histidine kinase
GsYM18_RS05745	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GsYM18_RS05750	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GsYM18_RS05755	COG3394	polysaccharide catabolic process
GsYM18_RS05780	COG0017	Asparaginyl-tRNA synthetase
GsYM18_RS05785	COG1550	Protein conserved in bacteria
GsYM18_RS05795	COG0693	protein deglycase activity
GsYM18_RS05805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GsYM18_RS05810	COG1136	(ABC) transporter
GsYM18_RS05810	COG0577	efflux transmembrane transporter activity
GsYM18_RS05845	COG1331	Highly conserved protein containing a thioredoxin domain
GsYM18_RS05860	COG3956	TIGRFAM MazG family protein
GsYM18_RS05865	COG0343	queuine tRNA-ribosyltransferase activity
GsYM18_RS05875	COG1053	succinate dehydrogenase
GsYM18_RS05890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GsYM18_RS05900	COG1640	4-alpha-glucanotransferase
GsYM18_RS05925	COG0501	Belongs to the peptidase M48B family
GsYM18_RS05930	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GsYM18_RS05965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GsYM18_RS05970	COG4085	toxin activity
GsYM18_RS05970	COG1525	nuclease
GsYM18_RS05970	COG0737	Belongs to the 5'-nucleotidase family
GsYM18_RS05980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GsYM18_RS05990	COG3263	regulation of cellular component size
GsYM18_RS06000	COG0655	NAD(P)H dehydrogenase (quinone) activity
GsYM18_RS06015	COG2860	membrane
GsYM18_RS06030	COG1403	HNH endonuclease
GsYM18_RS06040	COG3064	Membrane
GsYM18_RS06050	COG4988	ABC transporter
GsYM18_RS06055	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GsYM18_RS06065	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GsYM18_RS06070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GsYM18_RS06075	COG0745	RESPONSE REGULATOR receiver
GsYM18_RS06080	COG0004	ammonium transporteR
GsYM18_RS06085	COG0123	including yeast histone deacetylase and acetoin utilization protein
GsYM18_RS06140	COG0616	signal peptide processing
GsYM18_RS06150	COG0067	glutamate synthase
GsYM18_RS06160	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GsYM18_RS06180	COG0436	Aminotransferase
GsYM18_RS06185	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GsYM18_RS06190	COG0742	ribosomal rna small subunit methyltransferase
GsYM18_RS06200	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GsYM18_RS06215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GsYM18_RS06215	COG4191	Histidine kinase
GsYM18_RS06220	COG2204	response regulator
GsYM18_RS06275	COG1136	(ABC) transporter
GsYM18_RS06285	COG1534	Rna-binding protein
GsYM18_RS06300	COG0481	GTPase activity
GsYM18_RS06305	COG0681	Belongs to the peptidase S26 family
GsYM18_RS06310	COG0583	DNA-binding transcription factor activity
GsYM18_RS06320	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GsYM18_RS06325	COG0540	Belongs to the ATCase OTCase family
GsYM18_RS06330	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GsYM18_RS06335	COG0505	Belongs to the CarA family
GsYM18_RS06350	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GsYM18_RS06355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GsYM18_RS06365	COG0310	cobalt ion transport
GsYM18_RS06370	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GsYM18_RS06375	COG1122	ATPase activity
GsYM18_RS06395	COG0784	Response regulator, receiver
GsYM18_RS06395	COG2205	protein histidine kinase activity
GsYM18_RS06395	COG5002	protein histidine kinase activity
GsYM18_RS06420	COG0643	Histidine kinase
GsYM18_RS06420	COG2198	Histidine kinase
GsYM18_RS06440	COG3290	protein histidine kinase activity
GsYM18_RS06440	COG0840	transmembrane signaling receptor activity
GsYM18_RS06455	COG0840	transmembrane signaling receptor activity
GsYM18_RS06460	COG0835	chemotaxis
GsYM18_RS06470	COG0835	chemotaxis
GsYM18_RS06480	COG0840	transmembrane signaling receptor activity
GsYM18_RS06480	COG3290	protein histidine kinase activity
GsYM18_RS06485	COG0840	transmembrane signaling receptor activity
GsYM18_RS06490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GsYM18_RS06500	COG1528	Iron-storage protein
GsYM18_RS06515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GsYM18_RS06520	COG0166	Belongs to the GPI family
GsYM18_RS06550	COG0142	geranyltranstransferase activity
GsYM18_RS06560	COG4191	Histidine kinase
GsYM18_RS06565	COG2204	response regulator
GsYM18_RS06570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GsYM18_RS06575	COG0785	Cytochrome C biogenesis protein
GsYM18_RS06590	COG0724	RNA recognition motif
GsYM18_RS06595	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GsYM18_RS06600	COG0646	methionine synthase
GsYM18_RS06600	COG1410	methionine synthase
GsYM18_RS06605	COG3123	guanosine phosphorylase activity
GsYM18_RS06610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GsYM18_RS06625	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GsYM18_RS06640	COG0861	Integral membrane protein TerC family
GsYM18_RS06650	COG2217	Heavy metal translocating P-type atpase
GsYM18_RS06665	COG0577	efflux transmembrane transporter activity
GsYM18_RS06665	COG1136	(ABC) transporter
GsYM18_RS06675	COG0583	DNA-binding transcription factor activity
GsYM18_RS06680	COG1335	isochorismatase
GsYM18_RS06690	COG1959	2 iron, 2 sulfur cluster binding
GsYM18_RS06695	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GsYM18_RS06705	COG4208	sulfate ABC transporter
GsYM18_RS06710	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GsYM18_RS06735	COG1061	Type III restriction enzyme res subunit
GsYM18_RS06740	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GsYM18_RS06760	COG0667	Aldo Keto reductase
GsYM18_RS06765	COG1902	pentaerythritol trinitrate reductase activity
GsYM18_RS06770	COG2084	Dehydrogenase
GsYM18_RS06785	COG1024	Enoyl-CoA hydratase
GsYM18_RS06790	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GsYM18_RS06795	COG0735	belongs to the Fur family
GsYM18_RS06825	COG2132	Multicopper oxidase
GsYM18_RS06850	COG0598	Magnesium transport protein CorA
GsYM18_RS06865	COG0825	malonyl-CoA metabolic process
GsYM18_RS06870	COG1187	pseudouridine synthase activity
GsYM18_RS06875	COG0731	radical SAM domain protein
GsYM18_RS06875	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GsYM18_RS06890	COG0489	protein tyrosine kinase activity
GsYM18_RS06900	COG0822	iron-sulfur transferase activity
GsYM18_RS06905	COG1342	Belongs to the UPF0251 family
GsYM18_RS06965	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GsYM18_RS06970	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GsYM18_RS06975	COG4717	serine-type aminopeptidase activity
GsYM18_RS06980	COG0537	adenosine 5'-monophosphoramidase activity
GsYM18_RS06990	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GsYM18_RS07000	COG1366	Belongs to the anti-sigma-factor antagonist family
GsYM18_RS07005	COG2770	Histidine kinase
GsYM18_RS07005	COG2208	phosphoserine phosphatase activity
GsYM18_RS07030	COG0601	transmembrane transport
GsYM18_RS07035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GsYM18_RS07080	COG4771	TonB-dependent receptor
GsYM18_RS07105	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GsYM18_RS07115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GsYM18_RS07150	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GsYM18_RS07155	COG0442	prolyl-tRNA aminoacylation
GsYM18_RS07160	COG0284	orotidine-5'-phosphate decarboxylase activity
GsYM18_RS07165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GsYM18_RS07180	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GsYM18_RS07195	COG0039	L-malate dehydrogenase activity
GsYM18_RS07205	COG0674	pyruvate-flavodoxin oxidoreductase activity
GsYM18_RS07205	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GsYM18_RS07210	COG1013	pyruvate-flavodoxin oxidoreductase activity
GsYM18_RS07220	COG2770	Histidine kinase
GsYM18_RS07220	COG3437	response regulator, receiver
GsYM18_RS07245	COG4095	Psort location CytoplasmicMembrane, score
GsYM18_RS07250	COG1704	LemA family
GsYM18_RS07255	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GsYM18_RS07285	COG0741	lytic transglycosylase activity
GsYM18_RS07290	COG0557	exoribonuclease II activity
GsYM18_RS07295	COG0805	protein transport
GsYM18_RS07300	COG0196	riboflavin kinase activity
GsYM18_RS07315	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GsYM18_RS07320	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GsYM18_RS07330	COG1459	type II secretion system
GsYM18_RS07335	COG3852	Histidine kinase
GsYM18_RS07340	COG2204	response regulator
GsYM18_RS07345	COG4968	Prepilin-type N-terminal cleavage methylation domain
GsYM18_RS07365	COG1131	(ABC) transporter
GsYM18_RS07375	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GsYM18_RS07380	COG1216	Glycosyl transferase, family 2
GsYM18_RS07400	COG0438	transferase activity, transferring glycosyl groups
GsYM18_RS07430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GsYM18_RS07435	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GsYM18_RS07440	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GsYM18_RS07445	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GsYM18_RS07450	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GsYM18_RS07455	COG0072	phenylalanine-tRNA ligase activity
GsYM18_RS07475	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GsYM18_RS07480	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GsYM18_RS07490	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GsYM18_RS07500	COG3681	Belongs to the UPF0597 family
GsYM18_RS07505	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GsYM18_RS07515	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GsYM18_RS07520	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GsYM18_RS07530	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GsYM18_RS07535	COG1074	ATP-dependent DNA helicase activity
GsYM18_RS07540	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GsYM18_RS07550	COG3409	Peptidoglycan-binding domain 1 protein
GsYM18_RS07550	COG3267	Type II secretory pathway component ExeA
GsYM18_RS07560	COG0708	Exodeoxyribonuclease III
GsYM18_RS07665	COG1280	lysine exporter protein (LysE YggA)
GsYM18_RS07690	COG1942	4-Oxalocrotonate Tautomerase
GsYM18_RS07725	COG0668	transmembrane transport
GsYM18_RS07740	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GsYM18_RS07745	COG0011	TIGRFAM Protein of
GsYM18_RS07790	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GsYM18_RS07795	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GsYM18_RS07795	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GsYM18_RS07810	COG0617	tRNA 3'-terminal CCA addition
GsYM18_RS07810	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GsYM18_RS07810	COG3620	sequence-specific DNA binding
GsYM18_RS07815	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GsYM18_RS07820	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GsYM18_RS07825	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GsYM18_RS07830	COG0779	Required for maturation of 30S ribosomal subunits
GsYM18_RS07835	COG0195	Participates in both transcription termination and antitermination
GsYM18_RS07845	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GsYM18_RS07850	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GsYM18_RS07855	COG1227	inorganic diphosphatase activity
GsYM18_RS07860	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GsYM18_RS07865	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GsYM18_RS07870	COG1185	polyribonucleotide nucleotidyltransferase activity
GsYM18_RS07875	COG0612	Peptidase, M16
GsYM18_RS07880	COG0756	dUTP diphosphatase activity
GsYM18_RS07885	COG0009	L-threonylcarbamoyladenylate synthase
GsYM18_RS07900	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GsYM18_RS07905	COG0416	fatty acid biosynthetic process
GsYM18_RS07910	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GsYM18_RS07915	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GsYM18_RS07925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GsYM18_RS07930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GsYM18_RS07935	COG0698	ribose 5-phosphate isomerase
GsYM18_RS07940	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GsYM18_RS07965	COG0588	phosphoglycerate mutase activity
GsYM18_RS07985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GsYM18_RS07990	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GsYM18_RS08000	COG2201	protein-glutamate methylesterase activity
GsYM18_RS08005	COG1139	Iron-sulfur cluster binding protein
GsYM18_RS08015	COG1620	l-lactate permease
GsYM18_RS08020	COG0277	FAD linked oxidase domain protein
GsYM18_RS08025	COG0247	lactate metabolic process
GsYM18_RS08030	COG2186	Transcriptional regulator
GsYM18_RS08045	COG0149	triose-phosphate isomerase activity
GsYM18_RS08050	COG0126	phosphoglycerate kinase activity
GsYM18_RS08060	COG5002	protein histidine kinase activity
GsYM18_RS08065	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GsYM18_RS08070	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GsYM18_RS08075	COG0668	transmembrane transport
GsYM18_RS08080	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GsYM18_RS08085	COG0047	phosphoribosylformylglycinamidine synthase activity
GsYM18_RS08090	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GsYM18_RS08095	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GsYM18_RS08105	COG1959	2 iron, 2 sulfur cluster binding
GsYM18_RS08110	COG1271	oxidase subunit
GsYM18_RS08115	COG1294	oxidase, subunit
GsYM18_RS08130	COG0488	(ABC) transporter
GsYM18_RS08150	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GsYM18_RS08155	COG0723	plastoquinol--plastocyanin reductase activity
GsYM18_RS08160	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GsYM18_RS08170	COG2204	response regulator
GsYM18_RS08185	COG3447	MASE1 domain protein
GsYM18_RS08185	COG5002	protein histidine kinase activity
GsYM18_RS08185	COG5001	Diguanylate cyclase
GsYM18_RS08195	COG3706	GGDEF domain
GsYM18_RS08200	COG0124	histidyl-tRNA synthetase
GsYM18_RS08205	COG1049	propionate catabolic process, 2-methylcitrate cycle
GsYM18_RS08230	COG0705	Rhomboid family
GsYM18_RS08260	COG2205	protein histidine kinase activity
GsYM18_RS08260	COG3292	Two component regulator propeller
GsYM18_RS08260	COG0745	RESPONSE REGULATOR receiver
GsYM18_RS08265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GsYM18_RS08290	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GsYM18_RS08305	COG1492	cobalamin metabolic process
GsYM18_RS08330	COG2131	deaminase
GsYM18_RS08335	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GsYM18_RS08345	COG0307	riboflavin synthase, alpha
GsYM18_RS08350	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GsYM18_RS08350	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GsYM18_RS08355	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GsYM18_RS08360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GsYM18_RS08370	COG1011	Hydrolase
GsYM18_RS08380	COG0714	Associated with various cellular activities
GsYM18_RS08405	COG0281	malic enzyme
GsYM18_RS08405	COG0280	phosphate acetyltransferase
GsYM18_RS08415	COG1940	carbohydrate kinase activity
GsYM18_RS08430	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GsYM18_RS08435	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GsYM18_RS08440	COG0076	glutamate decarboxylase activity
GsYM18_RS08445	COG0402	S-adenosylhomocysteine deaminase activity
GsYM18_RS08450	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GsYM18_RS08465	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GsYM18_RS08495	COG0175	sulfate reduction
GsYM18_RS08500	COG0175	sulfate reduction
GsYM18_RS08515	COG0720	synthase
GsYM18_RS08520	COG0602	queuosine metabolic process
GsYM18_RS08540	COG0419	ATPase involved in DNA repair
GsYM18_RS08570	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GsYM18_RS08595	COG0683	leucine binding
GsYM18_RS08610	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GsYM18_RS08630	COG0248	Ppx GppA phosphatase
GsYM18_RS08630	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GsYM18_RS08655	COG0776	regulation of translation
GsYM18_RS08665	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GsYM18_RS08675	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GsYM18_RS08680	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GsYM18_RS08685	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GsYM18_RS08690	COG1509	lysine 2,3-aminomutase activity
GsYM18_RS08695	COG0167	dihydroorotate dehydrogenase activity
GsYM18_RS08710	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GsYM18_RS08715	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GsYM18_RS08740	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GsYM18_RS08750	COG1722	exodeoxyribonuclease VII activity
GsYM18_RS08755	COG1570	exodeoxyribonuclease VII activity
GsYM18_RS08760	COG1192	Involved in chromosome partitioning
GsYM18_RS08765	COG2861	carbohydrate metabolic process
GsYM18_RS08780	COG0793	Belongs to the peptidase S41A family
GsYM18_RS08790	COG2177	Part of the ABC transporter FtsEX involved in
GsYM18_RS08795	COG2884	Cell division ATP-binding protein ftsE
GsYM18_RS08810	COG4796	Type ii and iii secretion system protein
GsYM18_RS08835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GsYM18_RS08840	COG1459	type II secretion system
GsYM18_RS08870	COG0463	Glycosyl transferase, family 2
GsYM18_RS08890	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GsYM18_RS08895	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GsYM18_RS08900	COG0740	serine-type endopeptidase activity
GsYM18_RS08905	COG0544	peptidyl-prolyl cis-trans isomerase activity
GsYM18_RS08930	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GsYM18_RS08935	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GsYM18_RS08955	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GsYM18_RS08965	COG0802	atpase or kinase
GsYM18_RS08970	COG3620	sequence-specific DNA binding
GsYM18_RS08970	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GsYM18_RS08970	COG0617	tRNA 3'-terminal CCA addition
GsYM18_RS08975	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GsYM18_RS08975	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GsYM18_RS08980	COG0736	holo-[acyl-carrier-protein] synthase activity
GsYM18_RS08985	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GsYM18_RS08990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GsYM18_RS09000	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GsYM18_RS09005	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GsYM18_RS09010	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GsYM18_RS09015	COG0037	tRNA processing
GsYM18_RS09035	COG0018	arginyl-trna synthetase
GsYM18_RS09050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GsYM18_RS09065	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
GsYM18_RS09070	COG4974	Belongs to the 'phage' integrase family
GsYM18_RS09080	COG0860	N-Acetylmuramoyl-L-alanine amidase
GsYM18_RS09085	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GsYM18_RS09100	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GsYM18_RS09105	COG0741	lytic transglycosylase activity
GsYM18_RS09125	COG1355	regulation of microtubule-based process
GsYM18_RS09130	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GsYM18_RS09135	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GsYM18_RS09140	COG0180	Tryptophanyl-tRNA synthetase
GsYM18_RS09145	COG1994	Peptidase M50
GsYM18_RS09150	COG0174	glutamine synthetase
GsYM18_RS09160	COG0739	heme binding
GsYM18_RS09165	COG1643	Atp-dependent helicase
GsYM18_RS09170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GsYM18_RS09200	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GsYM18_RS09235	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GsYM18_RS09290	COG0674	pyruvate-flavodoxin oxidoreductase activity
GsYM18_RS09305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GsYM18_RS09310	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GsYM18_RS09315	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GsYM18_RS09340	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GsYM18_RS09360	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GsYM18_RS09380	COG0745	RESPONSE REGULATOR receiver
GsYM18_RS09385	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GsYM18_RS09390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GsYM18_RS09405	COG1660	Displays ATPase and GTPase activities
GsYM18_RS09410	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GsYM18_RS09415	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GsYM18_RS09440	COG3437	response regulator, receiver
GsYM18_RS09445	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GsYM18_RS09455	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GsYM18_RS09460	COG0504	CTP synthase activity
GsYM18_RS09465	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GsYM18_RS09485	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GsYM18_RS09500	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GsYM18_RS09505	COG1611	Belongs to the LOG family
GsYM18_RS09510	COG1278	Cold shock
GsYM18_RS09515	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GsYM18_RS09520	COG1183	phosphatidylcholine synthase activity
GsYM18_RS09525	COG0688	phosphatidylethanolamine metabolic process
GsYM18_RS09530	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GsYM18_RS09535	COG0440	acetolactate synthase activity
GsYM18_RS09540	COG0028	Belongs to the TPP enzyme family
GsYM18_RS09545	COG0129	dihydroxy-acid dehydratase activity
GsYM18_RS09550	COG1214	PFAM Peptidase M22, glycoprotease
GsYM18_RS09555	COG0750	zinc metalloprotease
GsYM18_RS09560	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GsYM18_RS09565	COG4589	Belongs to the CDS family
GsYM18_RS09570	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GsYM18_RS09575	COG0233	cytoplasmic translational termination
GsYM18_RS09580	COG0528	UMP kinase activity
GsYM18_RS09585	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GsYM18_RS09590	COG0052	Belongs to the universal ribosomal protein uS2 family
GsYM18_RS09595	COG0795	lipopolysaccharide-transporting ATPase activity
GsYM18_RS09635	COG1100	Small GTP-binding protein
GsYM18_RS09650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GsYM18_RS09655	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GsYM18_RS09685	COG2204	response regulator
GsYM18_RS09690	COG5000	phosphorelay sensor kinase activity
GsYM18_RS09730	COG2843	Capsule synthesis protein
GsYM18_RS09740	COG0367	asparagine synthase
GsYM18_RS09760	COG0438	transferase activity, transferring glycosyl groups
GsYM18_RS09775	COG1045	serine acetyltransferase
GsYM18_RS09780	COG1215	transferase activity, transferring glycosyl groups
GsYM18_RS09785	COG1216	Glycosyl transferase, family 2
GsYM18_RS09805	COG4310	Domain of unknown function (DUF2172)
GsYM18_RS09815	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GsYM18_RS09825	COG2089	acid synthase
GsYM18_RS09835	COG1083	cytidylyl-transferase
GsYM18_RS09845	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GsYM18_RS09850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GsYM18_RS09855	COG0438	transferase activity, transferring glycosyl groups
GsYM18_RS09860	COG1215	transferase activity, transferring glycosyl groups
GsYM18_RS09885	COG3267	Type II secretory pathway component ExeA
GsYM18_RS09885	COG3409	Peptidoglycan-binding domain 1 protein
GsYM18_RS09890	COG0489	protein tyrosine kinase activity
GsYM18_RS09905	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GsYM18_RS09920	COG2204	response regulator
GsYM18_RS09935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GsYM18_RS09960	COG0628	permease
GsYM18_RS09965	COG1923	regulation of RNA biosynthetic process
GsYM18_RS09970	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GsYM18_RS09975	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GsYM18_RS09980	COG0492	ferredoxin-NADP+ reductase activity
GsYM18_RS10020	COG2239	Acts as a magnesium transporter
GsYM18_RS10025	COG1104	cysteine desulfurase activity
GsYM18_RS10035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GsYM18_RS10055	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GsYM18_RS10060	COG0509	glycine decarboxylation via glycine cleavage system
GsYM18_RS10065	COG0439	Biotin carboxylase
GsYM18_RS10070	COG0511	ligase activity, forming carbon-carbon bonds
GsYM18_RS10075	COG0006	proline dipeptidase activity
GsYM18_RS10080	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GsYM18_RS10095	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GsYM18_RS10100	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GsYM18_RS10105	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GsYM18_RS10155	COG4969	Belongs to the N-Me-Phe pilin family
GsYM18_RS10175	COG2204	response regulator
GsYM18_RS10180	COG4191	Histidine kinase
GsYM18_RS10185	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GsYM18_RS10195	COG0525	valine-tRNA ligase activity
GsYM18_RS10215	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GsYM18_RS10220	COG0653	protein targeting
GsYM18_RS10225	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GsYM18_RS10240	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GsYM18_RS10260	COG0312	modulator of DNA gyrase
GsYM18_RS10265	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GsYM18_RS10285	COG0497	DNA recombination
GsYM18_RS10290	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GsYM18_RS10295	COG0058	SHG alpha-glucan phosphorylase activity
GsYM18_RS10300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GsYM18_RS10305	COG0205	6-phosphofructokinase activity
GsYM18_RS10310	COG0546	phosphoglycolate phosphatase activity
GsYM18_RS10320	COG0328	RNA-DNA hybrid ribonuclease activity
GsYM18_RS10335	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GsYM18_RS10355	COG0772	Belongs to the SEDS family
GsYM18_RS10360	COG0768	penicillin binding
GsYM18_RS10370	COG1792	Involved in formation and maintenance of cell shape
GsYM18_RS10380	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GsYM18_RS10385	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GsYM18_RS10390	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GsYM18_RS10390	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GsYM18_RS10400	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GsYM18_RS10415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GsYM18_RS10420	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GsYM18_RS10430	COG0488	(ABC) transporter
GsYM18_RS10440	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GsYM18_RS10450	COG1100	Small GTP-binding protein
GsYM18_RS10455	COG2204	response regulator
GsYM18_RS10480	COG0446	pyridine nucleotide-disulphide oxidoreductase
GsYM18_RS10485	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GsYM18_RS10500	COG3279	Response regulator of the LytR AlgR family
GsYM18_RS10505	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GsYM18_RS10545	COG0776	regulation of translation
GsYM18_RS10565	COG2003	Belongs to the UPF0758 family
GsYM18_RS10570	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GsYM18_RS10600	COG1401	restriction endodeoxyribonuclease activity
GsYM18_RS10610	COG3505	Type IV secretory pathway VirD4
GsYM18_RS10650	COG0582	viral genome integration into host DNA
GsYM18_RS10660	COG0617	tRNA 3'-terminal CCA addition
GsYM18_RS10675	COG0577	efflux transmembrane transporter activity
GsYM18_RS10700	COG0546	phosphoglycolate phosphatase activity
GsYM18_RS10710	COG0519	Catalyzes the synthesis of GMP from XMP
GsYM18_RS10710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GsYM18_RS10715	COG0517	IMP dehydrogenase activity
GsYM18_RS10715	COG0516	GMP reductase activity
GsYM18_RS10720	COG1363	Peptidase, m42
GsYM18_RS10730	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GsYM18_RS10750	COG0583	DNA-binding transcription factor activity
GsYM18_RS10770	COG0268	Binds directly to 16S ribosomal RNA
GsYM18_RS10775	COG1466	dna polymerase III delta subunit
GsYM18_RS10785	COG0495	leucyl-tRNA aminoacylation
GsYM18_RS10800	COG0745	RESPONSE REGULATOR receiver
GsYM18_RS10810	COG2201	protein-glutamate methylesterase activity
GsYM18_RS10815	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GsYM18_RS10830	COG0835	chemotaxis
GsYM18_RS10845	COG3409	Peptidoglycan-binding domain 1 protein
GsYM18_RS10845	COG3267	Type II secretory pathway component ExeA
GsYM18_RS10850	COG0643	Histidine kinase
GsYM18_RS10850	COG2198	Histidine kinase
GsYM18_RS10855	COG0745	RESPONSE REGULATOR receiver
GsYM18_RS10865	COG1160	GTP binding
GsYM18_RS10870	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GsYM18_RS10880	COG0571	ribonuclease III activity
GsYM18_RS10885	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GsYM18_RS10890	COG0470	DNA polymerase III
GsYM18_RS10895	COG1774	PSP1 C-terminal conserved region
GsYM18_RS10900	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GsYM18_RS10900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GsYM18_RS10910	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GsYM18_RS10925	COG1758	RNA polymerase activity
GsYM18_RS10930	COG0194	GDP metabolic process
GsYM18_RS10935	COG1561	YicC-like family, N-terminal region
GsYM18_RS10950	COG0859	PFAM glycosyl transferase family 9
GsYM18_RS10970	COG0859	PFAM glycosyl transferase family 9
GsYM18_RS10975	COG0438	transferase activity, transferring glycosyl groups
GsYM18_RS10995	COG2835	tetraacyldisaccharide 4'-kinase activity
GsYM18_RS11000	COG1663	tetraacyldisaccharide 4'-kinase activity
GsYM18_RS11005	COG1519	Transferase
GsYM18_RS11010	COG1132	(ABC) transporter
GsYM18_RS11015	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GsYM18_RS11025	COG0673	inositol 2-dehydrogenase activity
GsYM18_RS11035	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GsYM18_RS11040	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GsYM18_RS11050	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GsYM18_RS11055	COG1136	(ABC) transporter
GsYM18_RS11065	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GsYM18_RS11095	COG0791	NLP P60 protein
GsYM18_RS11115	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GsYM18_RS11120	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GsYM18_RS11125	COG1480	7TM receptor with intracellular HD hydrolase
GsYM18_RS11130	COG0148	phosphopyruvate hydratase activity
GsYM18_RS11135	COG0745	RESPONSE REGULATOR receiver
GsYM18_RS11140	COG4251	negative regulation of phosphorylation
GsYM18_RS11145	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GsYM18_RS11150	COG1335	isochorismatase
GsYM18_RS11155	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GsYM18_RS11160	COG0686	Belongs to the AlaDH PNT family
GsYM18_RS11185	COG2205	protein histidine kinase activity
GsYM18_RS11215	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GsYM18_RS11225	COG2885	chlorophyll binding
GsYM18_RS11235	COG0288	reversible hydration of carbon dioxide
GsYM18_RS11240	COG0281	malic enzyme
GsYM18_RS11245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GsYM18_RS11245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GsYM18_RS11250	COG2391	methyltransferase activity
GsYM18_RS11270	COG2205	protein histidine kinase activity
GsYM18_RS11270	COG0784	Response regulator, receiver
GsYM18_RS11270	COG5002	protein histidine kinase activity
GsYM18_RS11280	COG1196	nuclear chromosome segregation
GsYM18_RS11280	COG3264	Mechanosensitive ion channel
GsYM18_RS11285	COG3273	potassium ion transport
GsYM18_RS11285	COG0471	metal ion transport
GsYM18_RS11290	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GsYM18_RS11325	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GsYM18_RS11330	COG3040	lipid binding
GsYM18_RS11335	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
GsYM18_RS11345	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GsYM18_RS11365	COG1615	UPF0182 protein
GsYM18_RS11380	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GsYM18_RS11385	COG1320	monovalent cation:proton antiporter activity
GsYM18_RS11390	COG2212	antiporter activity
GsYM18_RS11395	COG1863	multisubunit Na H antiporter MnhE subunit
GsYM18_RS11400	COG0651	ATP synthesis coupled electron transport
GsYM18_RS11405	COG1006	Multisubunit Na H antiporter MnhC subunit
GsYM18_RS11410	COG2111	Na H antiporter
GsYM18_RS11415	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GsYM18_RS11415	COG2111	Na H antiporter
GsYM18_RS11420	COG2770	Histidine kinase
GsYM18_RS11420	COG2208	phosphoserine phosphatase activity
GsYM18_RS11440	COG3158	transport of potassium into the cell
GsYM18_RS11450	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GsYM18_RS11460	COG1414	Transcriptional regulator
GsYM18_RS11480	COG0668	transmembrane transport
GsYM18_RS11505	COG1846	Transcriptional regulator
GsYM18_RS11510	COG0038	chloride channel
GsYM18_RS11530	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GsYM18_RS11535	COG0285	dihydrofolate synthase activity
GsYM18_RS11540	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GsYM18_RS11545	COG0159	tryptophan synthase activity
GsYM18_RS11550	COG0840	transmembrane signaling receptor activity
GsYM18_RS11560	COG0741	lytic transglycosylase activity
GsYM18_RS11565	COG0133	tryptophan synthase activity
GsYM18_RS11575	COG0135	phosphoribosylanthranilate isomerase activity
GsYM18_RS11580	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GsYM18_RS11585	COG0134	indole-3-glycerol-phosphate synthase activity
GsYM18_RS11590	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GsYM18_RS11595	COG0512	Glutamine amidotransferase of anthranilate synthase
GsYM18_RS11600	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GsYM18_RS11625	COG0642	Histidine kinase
GsYM18_RS11635	COG0326	Molecular chaperone. Has ATPase activity
GsYM18_RS11680	COG0538	isocitrate dehydrogenase activity
GsYM18_RS11695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GsYM18_RS11710	COG0484	heat shock protein binding
GsYM18_RS11735	COG0071	Belongs to the small heat shock protein (HSP20) family
GsYM18_RS11750	COG0577	efflux transmembrane transporter activity
GsYM18_RS11750	COG1136	(ABC) transporter
GsYM18_RS11765	COG0835	chemotaxis
GsYM18_RS11775	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
GsYM18_RS11780	COG3259	Nickel-dependent hydrogenase
GsYM18_RS11810	COG2873	o-acetylhomoserine
GsYM18_RS11825	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GsYM18_RS11835	COG0330	HflC and HflK could
GsYM18_RS11850	COG1067	ATP-dependent peptidase activity
GsYM18_RS11855	COG0321	lipoyl(octanoyl) transferase activity
GsYM18_RS11865	COG0022	dehydrogenase e1 component
GsYM18_RS11880	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GsYM18_RS11895	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GsYM18_RS11900	COG5002	protein histidine kinase activity
GsYM18_RS11905	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GsYM18_RS11920	COG0508	dehydrogenase complex catalyzes the overall conversion of
GsYM18_RS11930	COG0517	IMP dehydrogenase activity
GsYM18_RS11930	COG0516	GMP reductase activity
GsYM18_RS11940	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GsYM18_RS11945	COG2217	Heavy metal translocating P-type atpase
GsYM18_RS11950	COG0628	permease
GsYM18_RS11955	COG0628	permease
GsYM18_RS11965	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GsYM18_RS11975	COG0768	penicillin binding
GsYM18_RS11980	COG1295	ribonuclease BN
GsYM18_RS11995	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GsYM18_RS12005	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GsYM18_RS12005	COG0321	lipoyl(octanoyl) transferase activity
GsYM18_RS12025	COG1204	response to ionizing radiation
GsYM18_RS12035	COG4456	Virulence-associated protein
GsYM18_RS12040	COG3550	peptidyl-serine autophosphorylation
GsYM18_RS12050	COG3437	response regulator, receiver
GsYM18_RS12060	COG2264	protein methyltransferase activity
GsYM18_RS12085	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GsYM18_RS12090	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GsYM18_RS12095	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GsYM18_RS12100	COG2205	protein histidine kinase activity
GsYM18_RS12105	COG0745	RESPONSE REGULATOR receiver
GsYM18_RS12110	COG3158	transport of potassium into the cell
GsYM18_RS12120	COG0549	Belongs to the carbamate kinase family
GsYM18_RS12130	COG0084	hydrolase, TatD family'
GsYM18_RS12135	COG2223	nitrite transmembrane transporter activity
GsYM18_RS12140	COG2814	Major facilitator Superfamily
GsYM18_RS12145	COG3852	Histidine kinase
GsYM18_RS12195	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GsYM18_RS12225	COG4191	Histidine kinase
GsYM18_RS12235	COG0463	Glycosyl transferase, family 2
GsYM18_RS12265	COG2897	thiosulfate sulfurtransferase activity
GsYM18_RS12275	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
GsYM18_RS12280	COG1924	4 iron, 4 sulfur cluster binding
GsYM18_RS12300	COG2204	response regulator
GsYM18_RS12315	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GsYM18_RS12325	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GsYM18_RS12330	COG1162	GTPase activity
GsYM18_RS12335	COG5002	protein histidine kinase activity
GsYM18_RS12350	COG3300	MHYT domain
GsYM18_RS12350	COG5001	Diguanylate cyclase
GsYM18_RS12365	COG1166	arginine decarboxylase activity
GsYM18_RS12380	COG1396	sequence-specific DNA binding
GsYM18_RS12385	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GsYM18_RS12400	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GsYM18_RS12405	COG0424	maF-like protein
GsYM18_RS12415	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GsYM18_RS12425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GsYM18_RS12430	COG0758	DNA mediated transformation
GsYM18_RS12430	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GsYM18_RS12440	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GsYM18_RS12455	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GsYM18_RS12460	COG0826	peptidase U32
GsYM18_RS12465	COG0726	polysaccharide deacetylase
GsYM18_RS12480	COG0248	Ppx GppA phosphatase
GsYM18_RS12495	COG2062	phosphohistidine phosphatase, SixA
GsYM18_RS12515	COG4251	negative regulation of phosphorylation
GsYM18_RS12520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GsYM18_RS12525	COG0482	sulfurtransferase activity
GsYM18_RS12530	COG1104	cysteine desulfurase activity
GsYM18_RS12535	COG1959	2 iron, 2 sulfur cluster binding
GsYM18_RS12540	COG1045	serine acetyltransferase
GsYM18_RS12555	COG0784	Response regulator, receiver
GsYM18_RS12555	COG2205	protein histidine kinase activity
GsYM18_RS12555	COG5002	protein histidine kinase activity
GsYM18_RS12570	COG0835	chemotaxis
GsYM18_RS12575	COG0840	transmembrane signaling receptor activity
GsYM18_RS12585	COG2204	response regulator
GsYM18_RS12600	COG1335	isochorismatase
GsYM18_RS12625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GsYM18_RS12635	COG2801	Transposase and inactivated derivatives
GsYM18_RS12650	COG0653	protein targeting
GsYM18_RS12655	COG4974	Belongs to the 'phage' integrase family
GsYM18_RS12685	COG1715	Restriction endonuclease
GsYM18_RS12715	COG3012	SEC-C Motif Domain Protein
GsYM18_RS12745	COG0776	regulation of translation
GsYM18_RS12755	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GsYM18_RS12760	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GsYM18_RS12765	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GsYM18_RS12770	COG0287	Prephenate dehydrogenase
GsYM18_RS12775	COG1605	Chorismate mutase
GsYM18_RS12775	COG0077	Prephenate dehydratase
GsYM18_RS12780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GsYM18_RS12800	COG1773	rubredoxin
GsYM18_RS12800	COG1592	Rubrerythrin
GsYM18_RS12805	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GsYM18_RS12810	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GsYM18_RS12810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GsYM18_RS12820	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GsYM18_RS12825	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GsYM18_RS12830	COG1862	Preprotein translocase
GsYM18_RS12835	COG0343	queuine tRNA-ribosyltransferase activity
GsYM18_RS12840	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GsYM18_RS12845	COG2385	sporulation resulting in formation of a cellular spore
GsYM18_RS12850	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GsYM18_RS12855	COG0444	Belongs to the ABC transporter superfamily
GsYM18_RS12860	COG4608	Belongs to the ABC transporter superfamily
GsYM18_RS12865	COG0640	Transcriptional regulator
GsYM18_RS12875	COG2226	methyltransferase
GsYM18_RS12880	COG2267	carboxylic ester hydrolase activity
GsYM18_RS12885	COG0156	8-amino-7-oxononanoate synthase activity
GsYM18_RS12890	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GsYM18_RS12995	COG0765	amino acid transport
GsYM18_RS13000	COG1126	abc transporter atp-binding protein
GsYM18_RS13015	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GsYM18_RS13020	COG0022	dehydrogenase e1 component
GsYM18_RS13030	COG2132	Multicopper oxidase
GsYM18_RS13070	COG1309	transcriptional regulator
GsYM18_RS13075	COG4251	negative regulation of phosphorylation
GsYM18_RS13085	COG4251	negative regulation of phosphorylation
GsYM18_RS13125	COG0697	spore germination
GsYM18_RS13150	COG0437	4 iron, 4 sulfur cluster binding
GsYM18_RS13155	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
GsYM18_RS13160	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GsYM18_RS13170	COG0842	Transport permease protein
GsYM18_RS13175	COG1129	ABC transporter
GsYM18_RS13175	COG0842	Transport permease protein
GsYM18_RS13180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GsYM18_RS13195	COG2853	Lipoprotein
GsYM18_RS13205	COG2358	TRAP transporter, solute receptor (TAXI family
GsYM18_RS13215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GsYM18_RS13220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GsYM18_RS13225	COG1309	transcriptional regulator
GsYM18_RS13245	COG3842	ATPase activity
GsYM18_RS13250	COG0303	'Molybdopterin
GsYM18_RS13255	COG0315	cyclic pyranopterin monophosphate synthase activity
GsYM18_RS13260	COG0521	Mo-molybdopterin cofactor biosynthetic process
GsYM18_RS13265	COG0280	phosphate acetyltransferase
GsYM18_RS13270	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GsYM18_RS13305	COG1489	DNA binding
GsYM18_RS13315	COG3259	Nickel-dependent hydrogenase
GsYM18_RS13320	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GsYM18_RS13325	COG1034	ATP synthesis coupled electron transport
GsYM18_RS13340	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GsYM18_RS13415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GsYM18_RS13445	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GsYM18_RS13455	COG4191	Histidine kinase
GsYM18_RS13455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GsYM18_RS13465	COG2201	protein-glutamate methylesterase activity
GsYM18_RS13475	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GsYM18_RS13485	COG2249	NAD(P)H dehydrogenase (quinone) activity
GsYM18_RS13490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GsYM18_RS13495	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GsYM18_RS13530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GsYM18_RS13555	COG2226	methyltransferase
GsYM18_RS13605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GsYM18_RS13610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GsYM18_RS13635	COG0583	DNA-binding transcription factor activity
GsYM18_RS13645	COG4251	negative regulation of phosphorylation
GsYM18_RS13655	COG0393	Putative heavy-metal-binding
GsYM18_RS13670	COG1970	mechanosensitive ion channel activity
GsYM18_RS13675	COG0247	lactate metabolic process
GsYM18_RS13675	COG2181	nitrate reductase activity
GsYM18_RS13680	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GsYM18_RS13730	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
GsYM18_RS13735	COG3108	Peptidase M15
GsYM18_RS13765	COG1592	Rubrerythrin
GsYM18_RS13770	COG4191	Histidine kinase
GsYM18_RS13780	COG0583	DNA-binding transcription factor activity
GsYM18_RS13785	COG2855	membrane
GsYM18_RS13790	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
GsYM18_RS13795	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
GsYM18_RS13810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GsYM18_RS13815	COG1131	(ABC) transporter
GsYM18_RS13820	COG1131	(ABC) transporter
GsYM18_RS13825	COG0842	Transport permease protein
GsYM18_RS13830	COG0842	Transport permease protein
GsYM18_RS13855	COG0203	ribosomal protein L17
GsYM18_RS13860	COG0202	RNA polymerase activity
GsYM18_RS13865	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GsYM18_RS13870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GsYM18_RS13875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GsYM18_RS13880	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GsYM18_RS13890	COG0563	adenylate kinase activity
GsYM18_RS13895	COG0201	protein transport
GsYM18_RS13900	COG0200	Binds to the 23S rRNA
GsYM18_RS13905	COG1841	ribosomal large subunit assembly
GsYM18_RS13910	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GsYM18_RS13915	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GsYM18_RS13920	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GsYM18_RS13925	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GsYM18_RS13935	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GsYM18_RS13940	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GsYM18_RS13945	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GsYM18_RS13950	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GsYM18_RS13955	COG0255	Belongs to the universal ribosomal protein uL29 family
GsYM18_RS13960	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GsYM18_RS13965	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GsYM18_RS13970	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GsYM18_RS13975	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GsYM18_RS13980	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GsYM18_RS13985	COG0089	rRNA binding
GsYM18_RS13990	COG0088	Forms part of the polypeptide exit tunnel
GsYM18_RS13995	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GsYM18_RS14000	COG0051	transcription antitermination factor activity, RNA binding
GsYM18_RS14005	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GsYM18_RS14010	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GsYM18_RS14015	COG0049	tRNA binding
GsYM18_RS14020	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GsYM18_RS14025	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GsYM18_RS14030	COG0085	RNA polymerase activity
GsYM18_RS14035	COG0222	ribosome binding
GsYM18_RS14040	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GsYM18_RS14045	COG0081	regulation of translation
GsYM18_RS14050	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GsYM18_RS14060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GsYM18_RS14070	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GsYM18_RS14075	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GsYM18_RS14105	COG1032	radical SAM domain protein
GsYM18_RS14110	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GsYM18_RS14120	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GsYM18_RS14125	COG0101	tRNA pseudouridine synthase activity
GsYM18_RS14135	COG0473	3-isopropylmalate dehydrogenase activity
GsYM18_RS14140	COG1138	Cytochrome C-type biogenesis protein
GsYM18_RS14195	COG2204	response regulator
GsYM18_RS14200	COG4191	Histidine kinase
GsYM18_RS14210	COG3958	Transketolase
GsYM18_RS14215	COG3959	Transketolase, thiamine diphosphate binding domain
GsYM18_RS14225	COG1410	methionine synthase
GsYM18_RS14225	COG0646	methionine synthase
GsYM18_RS14235	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GsYM18_RS14265	COG2703	oxygen carrier activity
GsYM18_RS14285	COG0723	plastoquinol--plastocyanin reductase activity
GsYM18_RS14285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GsYM18_RS14325	COG0583	DNA-binding transcription factor activity
GsYM18_RS14330	COG0840	transmembrane signaling receptor activity
GsYM18_RS14340	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
GsYM18_RS14360	COG1368	sulfuric ester hydrolase activity
GsYM18_RS14380	COG0640	Transcriptional regulator
GsYM18_RS14385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GsYM18_RS14390	COG0798	PFAM Bile acid sodium symporter
GsYM18_RS14405	COG3118	belongs to the thioredoxin family
GsYM18_RS14425	COG4149	molybdate abc transporter
GsYM18_RS14430	COG0725	ABC transporter, periplasmic molybdate-binding protein
GsYM18_RS14480	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GsYM18_RS14480	COG0646	methionine synthase
GsYM18_RS14490	COG0586	Pfam SNARE associated Golgi protein
GsYM18_RS14495	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GsYM18_RS14505	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GsYM18_RS14510	COG0864	Transcriptional regulator
GsYM18_RS14530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GsYM18_RS14535	COG1121	(ABC) transporter
GsYM18_RS14540	COG3443	Belongs to the bacterial solute-binding protein 9 family
GsYM18_RS14540	COG0803	Belongs to the bacterial solute-binding protein 9 family
GsYM18_RS14565	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GsYM18_RS14570	COG5002	protein histidine kinase activity
GsYM18_RS14575	COG1492	cobalamin metabolic process
GsYM18_RS14600	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
GsYM18_RS14620	COG1122	ATPase activity
GsYM18_RS14635	COG0310	cobalt ion transport
GsYM18_RS14640	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GsYM18_RS14645	COG1797	cobyrinic acid a,c-diamide synthase activity
GsYM18_RS14655	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GsYM18_RS14660	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GsYM18_RS14670	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GsYM18_RS14675	COG1418	mRNA catabolic process
GsYM18_RS14680	COG1334	flagellar protein FlaG
GsYM18_RS14690	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GsYM18_RS14725	COG0189	ligase activity
GsYM18_RS14740	COG0463	Glycosyl transferase, family 2
GsYM18_RS14740	COG1216	Glycosyl transferase, family 2
GsYM18_RS14740	COG1216	Glycosyl transferase, family 2
GsYM18_RS14740	COG0463	Glycosyl transferase, family 2
GsYM18_RS14745	COG4641	Protein conserved in bacteria
GsYM18_RS14750	COG0859	PFAM glycosyl transferase family 9
GsYM18_RS14765	COG1360	Flagellar Motor Protein
GsYM18_RS14770	COG0318	PFAM AMP-dependent synthetase and ligase
GsYM18_RS14770	COG0204	Acyl-transferase
GsYM18_RS14810	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GsYM18_RS14815	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GsYM18_RS14820	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GsYM18_RS14825	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GsYM18_RS14830	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GsYM18_RS14855	COG1706	bacterial-type flagellum-dependent cell motility
GsYM18_RS14860	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GsYM18_RS14880	COG1191	sigma factor activity
GsYM18_RS14890	COG1419	protein localization to endoplasmic reticulum
GsYM18_RS14895	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GsYM18_RS14900	COG0493	'glutamate synthase
GsYM18_RS14900	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GsYM18_RS14905	COG0543	2 iron, 2 sulfur cluster binding
GsYM18_RS14915	COG1309	transcriptional regulator
GsYM18_RS14920	COG1657	PFAM Prenyltransferase squalene oxidase
GsYM18_RS14930	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GsYM18_RS14940	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GsYM18_RS14945	COG1181	Belongs to the D-alanine--D-alanine ligase family
GsYM18_RS14950	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GsYM18_RS14955	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GsYM18_RS14960	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GsYM18_RS14970	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GsYM18_RS14975	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GsYM18_RS14980	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GsYM18_RS14985	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GsYM18_RS14990	COG0768	penicillin binding
GsYM18_RS14995	COG3116	cell division
GsYM18_RS15000	COG0275	rRNA processing
GsYM18_RS15005	COG2001	Belongs to the MraZ family
GsYM18_RS15030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GsYM18_RS15040	COG0116	Belongs to the methyltransferase superfamily
GsYM18_RS15060	COG0358	DNA primase activity
GsYM18_RS15070	COG1610	YqeY-like protein
GsYM18_RS15075	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GsYM18_RS15080	COG0140	phosphoribosyl-ATP diphosphatase activity
GsYM18_RS15085	COG0107	imidazoleglycerol-phosphate synthase activity
GsYM18_RS15090	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GsYM18_RS15095	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GsYM18_RS15100	COG0131	Imidazoleglycerol-phosphate dehydratase
GsYM18_RS15105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GsYM18_RS15110	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GsYM18_RS15115	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GsYM18_RS15120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GsYM18_RS15125	COG2890	protein-(glutamine-N5) methyltransferase activity
GsYM18_RS15130	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GsYM18_RS15135	COG3872	metal-dependent enzyme
GsYM18_RS15140	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
GsYM18_RS15145	COG0254	rRNA binding
GsYM18_RS15150	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GsYM18_RS15155	COG1414	Transcriptional regulator
GsYM18_RS15170	COG1674	ftsk spoiiie
GsYM18_RS15175	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GsYM18_RS15195	COG0629	single-stranded DNA binding
GsYM18_RS15230	COG4221	oxidoreductase activity
GsYM18_RS15255	COG0534	Mate efflux family protein
GsYM18_RS15285	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GsYM18_RS15290	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GsYM18_RS15300	COG5002	protein histidine kinase activity
GsYM18_RS15320	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GsYM18_RS15325	COG1047	Peptidyl-prolyl cis-trans
GsYM18_RS15330	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GsYM18_RS15340	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GsYM18_RS15345	COG0746	molybdenum cofactor guanylyltransferase activity
GsYM18_RS15350	COG4191	Histidine kinase
GsYM18_RS15365	COG4191	Histidine kinase
GsYM18_RS15370	COG0348	domain, Protein
GsYM18_RS15375	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GsYM18_RS15385	COG0840	transmembrane signaling receptor activity
GsYM18_RS15410	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GsYM18_RS15440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GsYM18_RS15495	COG3501	Rhs element vgr protein
GsYM18_RS15545	COG1773	rubredoxin
GsYM18_RS15555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GsYM18_RS15570	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GsYM18_RS15575	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GsYM18_RS15585	COG0840	transmembrane signaling receptor activity
GsYM18_RS15595	COG2201	protein-glutamate methylesterase activity
GsYM18_RS15600	COG2198	Histidine kinase
GsYM18_RS15600	COG0643	Histidine kinase
GsYM18_RS15605	COG1776	CheC inhibitor of MCP methylation
GsYM18_RS15610	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GsYM18_RS15625	COG1666	GTP binding
GsYM18_RS15630	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GsYM18_RS15640	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GsYM18_RS15645	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GsYM18_RS15650	COG0799	negative regulation of ribosome biogenesis
GsYM18_RS15655	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GsYM18_RS15660	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GsYM18_RS15665	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GsYM18_RS15670	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GsYM18_RS15690	COG2204	response regulator
GsYM18_RS15745	COG2197	response regulator
GsYM18_RS15765	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GsYM18_RS15770	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GsYM18_RS15775	COG2146	nitrite reductase [NAD(P)H] activity
GsYM18_RS15775	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GsYM18_RS15785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GsYM18_RS15810	COG0450	alkyl hydroperoxide reductase
GsYM18_RS15825	COG0617	tRNA 3'-terminal CCA addition
GsYM18_RS15850	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GsYM18_RS15865	COG0297	glycogen (starch) synthase activity
GsYM18_RS15875	COG3005	denitrification pathway
GsYM18_RS15885	COG0784	Response regulator, receiver
GsYM18_RS15890	COG0556	nucleotide-excision repair
GsYM18_RS15895	COG0745	RESPONSE REGULATOR receiver
GsYM18_RS15905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GsYM18_RS15950	COG3706	GGDEF domain
GsYM18_RS15960	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GsYM18_RS15960	COG1918	ferrous iron import across plasma membrane
GsYM18_RS16015	COG0322	excinuclease ABC activity
GsYM18_RS16020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GsYM18_RS16025	COG3118	belongs to the thioredoxin family
GsYM18_RS16030	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GsYM18_RS16030	COG1648	precorrin-2 dehydrogenase activity
GsYM18_RS16035	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GsYM18_RS16040	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GsYM18_RS16045	COG0181	hydroxymethylbilane synthase activity
GsYM18_RS16055	COG0084	hydrolase, TatD family'
GsYM18_RS16060	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GsYM18_RS16075	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GsYM18_RS16095	COG0426	domain, Protein
GsYM18_RS16100	COG3875	lactate racemase activity
GsYM18_RS16105	COG0277	FAD linked oxidase domain protein
GsYM18_RS16135	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GsYM18_RS16135	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GsYM18_RS16140	COG0346	lactoylglutathione lyase activity
GsYM18_RS16160	COG0124	histidyl-tRNA synthetase
GsYM18_RS16165	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GsYM18_RS16190	COG2205	protein histidine kinase activity
GsYM18_RS16195	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GsYM18_RS16240	COG2264	protein methyltransferase activity
GsYM18_RS16245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GsYM18_RS16250	COG0598	Magnesium transport protein CorA
GsYM18_RS16255	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GsYM18_RS16260	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GsYM18_RS16265	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GsYM18_RS16285	COG0305	Participates in initiation and elongation during chromosome replication
GsYM18_RS16315	COG0741	lytic transglycosylase activity
GsYM18_RS16380	COG0632	four-way junction helicase activity
GsYM18_RS16385	COG0446	pyridine nucleotide-disulphide oxidoreductase
GsYM18_RS16385	COG1902	pentaerythritol trinitrate reductase activity
GsYM18_RS16400	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GsYM18_RS16425	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GsYM18_RS16430	COG0459	protein refolding
GsYM18_RS16445	COG2719	SpoVR family
GsYM18_RS16460	COG3158	transport of potassium into the cell
GsYM18_RS16465	COG0826	peptidase U32
GsYM18_RS16470	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GsYM18_RS16505	COG3706	GGDEF domain
GsYM18_RS16510	COG4251	negative regulation of phosphorylation
GsYM18_RS16525	COG0612	Peptidase, M16
GsYM18_RS16550	COG0215	cysteine-tRNA ligase activity
GsYM18_RS16555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GsYM18_RS16560	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GsYM18_RS16565	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GsYM18_RS16570	COG1921	L-seryl-tRNASec selenium transferase activity
GsYM18_RS16575	COG2186	Transcriptional regulator
GsYM18_RS16585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GsYM18_RS16590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GsYM18_RS16590	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GsYM18_RS16595	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GsYM18_RS16615	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GsYM18_RS16620	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GsYM18_RS16625	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GsYM18_RS16630	COG0154	amidase activity
GsYM18_RS16640	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GsYM18_RS16645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GsYM18_RS16650	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
GsYM18_RS16670	COG0697	spore germination
GsYM18_RS16705	COG1012	belongs to the aldehyde dehydrogenase family
GsYM18_RS16710	COG2186	Transcriptional regulator
GsYM18_RS16755	COG0765	amino acid transport
GsYM18_RS16800	COG1032	radical SAM domain protein
GsYM18_RS16815	COG2204	response regulator
GsYM18_RS16820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GsYM18_RS16820	COG4191	Histidine kinase
GsYM18_RS16870	COG1007	ATP synthesis coupled electron transport
GsYM18_RS16880	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GsYM18_RS16885	COG0713	ATP synthesis coupled electron transport
GsYM18_RS16895	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GsYM18_RS16905	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GsYM18_RS16910	COG4251	negative regulation of phosphorylation
GsYM18_RS16915	COG2824	Alkylphosphonate utilization operon protein PhnA
GsYM18_RS16930	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GsYM18_RS16945	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GsYM18_RS16945	COG0649	NAD binding
GsYM18_RS16945	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GsYM18_RS16950	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GsYM18_RS16960	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GsYM18_RS16965	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GsYM18_RS16975	COG0070	glutamate synthase
GsYM18_RS16975	COG0069	glutamate synthase activity
GsYM18_RS16975	COG0067	glutamate synthase
GsYM18_RS16990	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GsYM18_RS16995	COG0535	radical SAM domain protein
GsYM18_RS17005	COG0242	peptide deformylase activity
GsYM18_RS17010	COG3830	Belongs to the UPF0237 family
GsYM18_RS17020	COG1216	Glycosyl transferase, family 2
GsYM18_RS17025	COG0824	Thioesterase
GsYM18_RS17035	COG0357	Ribosomal RNA small subunit methyltransferase G
GsYM18_RS17040	COG0445	tRNA wobble uridine modification
GsYM18_RS17045	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GsYM18_RS17050	COG0706	membrane insertase activity
GsYM18_RS17055	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GsYM18_RS17065	COG0230	Belongs to the bacterial ribosomal protein bL34 family