locus-tag	class	description
EBO36_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EBO36_RS00010	COG0592	DNA-directed DNA polymerase activity
EBO36_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EBO36_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EBO36_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
EBO36_RS00030	COG0187	DNA topoisomerase II activity
EBO36_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EBO36_RS00090	COG3764	Sortase (surface protein transpeptidase)
EBO36_RS00100	COG0515	serine threonine protein kinase
EBO36_RS00105	COG0515	serine threonine protein kinase
EBO36_RS00110	COG0768	penicillin binding
EBO36_RS00125	COG1716	ATPase activity
EBO36_RS00130	COG1716	ATPase activity
EBO36_RS00130	COG1131	(ABC) transporter
EBO36_RS00130	COG0842	Transport permease protein
EBO36_RS00145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EBO36_RS00160	COG2116	formate transmembrane transporter activity
EBO36_RS00175	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EBO36_RS00190	COG1780	Probably involved in ribonucleotide reductase function
EBO36_RS00195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBO36_RS00200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBO36_RS00205	COG1028	Short-chain dehydrogenase reductase Sdr
EBO36_RS00235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBO36_RS00240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBO36_RS00245	COG2818	Glycosylase
EBO36_RS00250	COG1472	Belongs to the glycosyl hydrolase 3 family
EBO36_RS00285	COG1309	transcriptional regulator
EBO36_RS00290	COG2971	BadF BadG BcrA BcrD
EBO36_RS00295	COG0395	ABC-type sugar transport system, permease component
EBO36_RS00300	COG1175	transmembrane transport
EBO36_RS00310	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EBO36_RS00315	COG1737	Transcriptional regulator
EBO36_RS00320	COG1082	Xylose isomerase domain protein TIM barrel
EBO36_RS00340	COG1175	transmembrane transport
EBO36_RS00345	COG3833	ABC-type maltose transport systems, permease component
EBO36_RS00365	COG2072	flavoprotein involved in K transport
EBO36_RS00370	COG1643	Atp-dependent helicase
EBO36_RS00385	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EBO36_RS00390	COG2340	Cysteine-rich secretory protein family
EBO36_RS00400	COG1764	response to oxidative stress
EBO36_RS00425	COG1929	Belongs to the glycerate kinase type-1 family
EBO36_RS00430	COG0800	Aldolase
EBO36_RS00435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBO36_RS00450	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EBO36_RS00450	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EBO36_RS00460	COG0673	inositol 2-dehydrogenase activity
EBO36_RS00475	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EBO36_RS00480	COG1028	Short-chain dehydrogenase reductase Sdr
EBO36_RS00485	COG0683	leucine binding
EBO36_RS00530	COG0425	Belongs to the sulfur carrier protein TusA family
EBO36_RS00530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EBO36_RS00540	COG1215	transferase activity, transferring glycosyl groups
EBO36_RS00550	COG0077	Prephenate dehydratase
EBO36_RS00565	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EBO36_RS00570	COG0561	phosphatase activity
EBO36_RS00575	COG1653	transport
EBO36_RS00580	COG1175	transmembrane transport
EBO36_RS00585	COG0395	ABC-type sugar transport system, permease component
EBO36_RS00595	COG0789	Transcriptional regulator
EBO36_RS00600	COG1028	Short-chain dehydrogenase reductase Sdr
EBO36_RS00600	COG3321	synthase
EBO36_RS00600	COG0604	alcohol dehydrogenase
EBO36_RS00630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBO36_RS00640	COG1609	Transcriptional regulator
EBO36_RS00655	COG4120	Belongs to the binding-protein-dependent transport system permease family
EBO36_RS00660	COG1122	ATPase activity
EBO36_RS00670	COG1846	Transcriptional regulator
EBO36_RS00680	COG2267	carboxylic ester hydrolase activity
EBO36_RS00685	COG1254	Belongs to the acylphosphatase family
EBO36_RS00690	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EBO36_RS00695	COG0590	tRNA wobble adenosine to inosine editing
EBO36_RS00705	COG0531	amino acid
EBO36_RS00715	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBO36_RS00715	COG0519	Catalyzes the synthesis of GMP from XMP
EBO36_RS00725	COG2233	PERMEase
EBO36_RS00740	COG1295	ribonuclease BN
EBO36_RS00765	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EBO36_RS00785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBO36_RS00800	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EBO36_RS00805	COG0438	transferase activity, transferring glycosyl groups
EBO36_RS00810	COG0489	protein tyrosine kinase activity
EBO36_RS00835	COG1408	metallophosphoesterase
EBO36_RS00840	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EBO36_RS00870	COG2267	carboxylic ester hydrolase activity
EBO36_RS00875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EBO36_RS00890	COG2116	formate transmembrane transporter activity
EBO36_RS00900	COG3546	catalase activity
EBO36_RS00945	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EBO36_RS00950	COG0737	Belongs to the 5'-nucleotidase family
EBO36_RS00955	COG0588	phosphoglycerate mutase activity
EBO36_RS00960	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EBO36_RS00970	COG1028	Short-chain dehydrogenase reductase Sdr
EBO36_RS00985	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBO36_RS00985	COG1754	DNA topoisomerase type I activity
EBO36_RS00995	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EBO36_RS01000	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EBO36_RS01075	COG0588	phosphoglycerate mutase activity
EBO36_RS01085	COG5002	protein histidine kinase activity
EBO36_RS01090	COG0745	RESPONSE REGULATOR receiver
EBO36_RS01105	COG1329	Transcriptional regulator
EBO36_RS01110	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EBO36_RS01115	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EBO36_RS01125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EBO36_RS01135	COG0215	cysteine-tRNA ligase activity
EBO36_RS01155	COG3842	ATPase activity
EBO36_RS01200	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EBO36_RS01215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EBO36_RS01230	COG3395	kinase activity
EBO36_RS01235	COG1349	DNA-binding transcription factor activity
EBO36_RS01275	COG1175	transmembrane transport
EBO36_RS01280	COG0395	ABC-type sugar transport system, permease component
EBO36_RS01295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBO36_RS01300	COG1609	Transcriptional regulator
EBO36_RS01320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBO36_RS01330	COG1070	Carbohydrate kinase
EBO36_RS01335	COG2115	Belongs to the xylose isomerase family
EBO36_RS01375	COG0459	protein refolding
EBO36_RS01385	COG4172	Belongs to the ABC transporter superfamily
EBO36_RS01390	COG4721	ABC-type cobalt transport system, permease component
EBO36_RS01430	COG2205	protein histidine kinase activity
EBO36_RS01435	COG0745	RESPONSE REGULATOR receiver
EBO36_RS01450	COG1842	Phage shock protein A
EBO36_RS01460	COG0505	Belongs to the CarA family
EBO36_RS01475	COG1129	ABC transporter
EBO36_RS01480	COG1172	Belongs to the binding-protein-dependent transport system permease family
EBO36_RS01485	COG1879	ABC-type sugar transport system periplasmic component
EBO36_RS01490	COG0673	inositol 2-dehydrogenase activity
EBO36_RS01515	COG1129	ABC transporter
EBO36_RS01520	COG1172	Belongs to the binding-protein-dependent transport system permease family
EBO36_RS01540	COG3507	Belongs to the glycosyl hydrolase 43 family
EBO36_RS01580	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EBO36_RS01585	COG0142	geranyltranstransferase activity
EBO36_RS01590	COG1061	Type III restriction enzyme res subunit
EBO36_RS01600	COG0702	epimerase
EBO36_RS01635	COG1278	Cold shock
EBO36_RS01655	COG0681	Belongs to the peptidase S26 family
EBO36_RS01670	COG0697	spore germination
EBO36_RS01675	COG1846	Transcriptional regulator
EBO36_RS01685	COG1131	(ABC) transporter
EBO36_RS01690	COG4585	Histidine kinase
EBO36_RS01695	COG2197	response regulator
EBO36_RS01700	COG4942	peptidase
EBO36_RS01715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EBO36_RS01745	COG3104	oligopeptide transport
EBO36_RS01755	COG2390	Transcriptional regulator
EBO36_RS01765	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EBO36_RS01770	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EBO36_RS01800	COG3250	beta-galactosidase activity
EBO36_RS01820	COG0489	protein tyrosine kinase activity
EBO36_RS01840	COG5039	Polysaccharide pyruvyl transferase
EBO36_RS01880	COG1086	Polysaccharide biosynthesis protein
EBO36_RS01900	COG0235	Class ii aldolase
EBO36_RS01905	COG3395	kinase activity
EBO36_RS01910	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EBO36_RS01915	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EBO36_RS01915	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EBO36_RS01920	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EBO36_RS01945	COG1028	Short-chain dehydrogenase reductase Sdr
EBO36_RS01955	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EBO36_RS01985	COG2814	Major facilitator Superfamily
EBO36_RS01990	COG3173	Aminoglycoside phosphotransferase
EBO36_RS02000	COG0456	acetyltransferase
EBO36_RS02000	COG1214	PFAM Peptidase M22, glycoprotease
EBO36_RS02005	COG0702	epimerase
EBO36_RS02010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBO36_RS02030	COG4585	Histidine kinase
EBO36_RS02035	COG2197	response regulator
EBO36_RS02045	COG2132	Multicopper oxidase
EBO36_RS02060	COG0740	serine-type endopeptidase activity
EBO36_RS02065	COG0740	serine-type endopeptidase activity
EBO36_RS02075	COG1674	ftsk spoiiie
EBO36_RS02170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBO36_RS02180	COG2252	PERMEase
EBO36_RS02195	COG2814	Major facilitator Superfamily
EBO36_RS02200	COG0477	Major facilitator Superfamily
EBO36_RS02210	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EBO36_RS02215	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EBO36_RS02240	COG1834	amidinotransferase
EBO36_RS02280	COG0745	RESPONSE REGULATOR receiver
EBO36_RS02295	COG1823	symporter activity
EBO36_RS02305	COG3291	Pkd domain containing protein
EBO36_RS02305	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EBO36_RS02320	COG0366	Alpha amylase catalytic
EBO36_RS02325	COG0667	Aldo Keto reductase
EBO36_RS02345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EBO36_RS02350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EBO36_RS02355	COG1120	ATPase activity
EBO36_RS02365	COG1028	Short-chain dehydrogenase reductase Sdr
EBO36_RS02385	COG1970	mechanosensitive ion channel activity
EBO36_RS02405	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EBO36_RS02470	COG1012	belongs to the aldehyde dehydrogenase family
EBO36_RS02500	COG1335	isochorismatase
EBO36_RS02505	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EBO36_RS02510	COG0084	hydrolase, TatD family'
EBO36_RS02525	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EBO36_RS02530	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EBO36_RS02535	COG0488	(ABC) transporter
EBO36_RS02540	COG1556	Lactate utilization protein
EBO36_RS02545	COG1139	Iron-sulfur cluster binding protein
EBO36_RS02550	COG0247	lactate metabolic process
EBO36_RS02555	COG1620	l-lactate permease
EBO36_RS02565	COG1846	Transcriptional regulator
EBO36_RS02570	COG1668	transmembrane transport
EBO36_RS02575	COG4152	abc transporter atp-binding protein
EBO36_RS02590	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EBO36_RS02600	COG1846	Transcriptional regulator
EBO36_RS02605	COG1902	pentaerythritol trinitrate reductase activity
EBO36_RS02605	COG0446	pyridine nucleotide-disulphide oxidoreductase
EBO36_RS02610	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EBO36_RS02615	COG0193	aminoacyl-tRNA hydrolase activity
EBO36_RS02620	COG1132	(ABC) transporter
EBO36_RS02645	COG0148	phosphopyruvate hydratase activity
EBO36_RS02665	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EBO36_RS02680	COG1252	NADH dehydrogenase
EBO36_RS02700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBO36_RS02705	COG0545	Peptidyl-prolyl cis-trans isomerase
EBO36_RS02715	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EBO36_RS02725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EBO36_RS02730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBO36_RS02740	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EBO36_RS02760	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EBO36_RS02765	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EBO36_RS02775	COG1722	exodeoxyribonuclease VII activity
EBO36_RS02780	COG1570	exodeoxyribonuclease VII activity
EBO36_RS02800	COG1322	Protein conserved in bacteria
EBO36_RS02810	COG0012	GTP binding
EBO36_RS02835	COG0154	amidase activity
EBO36_RS02910	COG1136	(ABC) transporter
EBO36_RS02915	COG1136	(ABC) transporter
EBO36_RS02920	COG1217	gtp-binding protein TYPA
EBO36_RS02930	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EBO36_RS02965	COG2197	response regulator
EBO36_RS03000	COG4770	biotin carboxylase activity
EBO36_RS03005	COG0424	maF-like protein
EBO36_RS03025	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EBO36_RS03040	COG0745	RESPONSE REGULATOR receiver
EBO36_RS03045	COG2205	protein histidine kinase activity
EBO36_RS03070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EBO36_RS03075	COG1832	CoA-binding protein
EBO36_RS03080	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EBO36_RS03085	COG1316	TRANSCRIPTIONal
EBO36_RS03090	COG1316	TRANSCRIPTIONal
EBO36_RS03105	COG2171	N-acyltransferase activity
EBO36_RS03110	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EBO36_RS03140	COG1132	(ABC) transporter
EBO36_RS03160	COG0438	transferase activity, transferring glycosyl groups
EBO36_RS03160	COG0297	glycogen (starch) synthase activity
EBO36_RS03195	COG1672	PFAM Archaeal ATPase
EBO36_RS03195	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EBO36_RS03230	COG1482	cell wall glycoprotein biosynthetic process
EBO36_RS03265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EBO36_RS03265	COG2755	lipolytic protein G-D-S-L family
EBO36_RS03275	COG2835	tetraacyldisaccharide 4'-kinase activity
EBO36_RS03285	COG2378	regulation of single-species biofilm formation
EBO36_RS03300	COG4175	Glycine betaine
EBO36_RS03300	COG0517	IMP dehydrogenase activity
EBO36_RS03305	COG1472	Belongs to the glycosyl hydrolase 3 family
EBO36_RS03310	COG1472	Belongs to the glycosyl hydrolase 3 family
EBO36_RS03315	COG1472	Belongs to the glycosyl hydrolase 3 family
EBO36_RS03340	COG0714	Associated with various cellular activities
EBO36_RS03360	COG0745	RESPONSE REGULATOR receiver
EBO36_RS03365	COG5002	protein histidine kinase activity
EBO36_RS03370	COG5401	PFAM Sporulation and spore germination
EBO36_RS03380	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EBO36_RS03385	COG3214	Protein conserved in bacteria
EBO36_RS03390	COG0653	protein targeting
EBO36_RS03405	COG0431	NADPH-dependent FMN reductase
EBO36_RS03465	COG0419	ATPase involved in DNA repair
EBO36_RS03470	COG0420	3'-5' exonuclease activity
EBO36_RS03475	COG0483	inositol monophosphate 1-phosphatase activity
EBO36_RS03480	COG1162	GTPase activity
EBO36_RS03485	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EBO36_RS03495	COG1595	DNA-templated transcription, initiation
EBO36_RS03520	COG0508	dehydrogenase complex catalyzes the overall conversion of
EBO36_RS03520	COG0567	Dehydrogenase, E1 component
EBO36_RS03555	COG0018	arginyl-trna synthetase
EBO36_RS03560	COG0019	diaminopimelate decarboxylase activity
EBO36_RS03565	COG0460	homoserine dehydrogenase
EBO36_RS03570	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EBO36_RS03575	COG0083	homoserine kinase activity
EBO36_RS03585	COG0254	rRNA binding
EBO36_RS03590	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EBO36_RS03595	COG2890	protein-(glutamine-N5) methyltransferase activity
EBO36_RS03610	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBO36_RS03620	COG0356	it plays a direct role in the translocation of protons across the membrane
EBO36_RS03625	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EBO36_RS03630	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EBO36_RS03635	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EBO36_RS03640	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EBO36_RS03645	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EBO36_RS03650	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EBO36_RS03655	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EBO36_RS03665	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
EBO36_RS03670	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EBO36_RS03720	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EBO36_RS03730	COG0366	Alpha amylase catalytic
EBO36_RS03735	COG0058	SHG alpha-glucan phosphorylase activity
EBO36_RS03755	COG2086	electron transfer activity
EBO36_RS03760	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EBO36_RS03780	COG3226	Transcriptional regulator
EBO36_RS03810	COG1132	(ABC) transporter
EBO36_RS03835	COG0444	Belongs to the ABC transporter superfamily
EBO36_RS03840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EBO36_RS03845	COG0601	transmembrane transport
EBO36_RS03850	COG0747	negative chemotaxis
EBO36_RS03870	COG0482	sulfurtransferase activity
EBO36_RS03880	COG3268	Saccharopine dehydrogenase
EBO36_RS03890	COG1196	nuclear chromosome segregation
EBO36_RS03890	COG0741	lytic transglycosylase activity
EBO36_RS03890	COG0739	heme binding
EBO36_RS03895	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBO36_RS03935	COG0129	dihydroxy-acid dehydratase activity
EBO36_RS03960	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EBO36_RS03975	COG0473	3-isopropylmalate dehydrogenase activity
EBO36_RS03980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EBO36_RS03985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EBO36_RS03995	COG0095	Lipoate-protein ligase
EBO36_RS04060	COG0110	maltose O-acetyltransferase activity
EBO36_RS04065	COG1793	dna ligase
EBO36_RS04080	COG3546	catalase activity
EBO36_RS04085	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBO36_RS04085	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBO36_RS04110	COG0179	Fumarylacetoacetate (FAA) hydrolase
EBO36_RS04180	COG2011	ABC-type metal ion transport system permease component
EBO36_RS04190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EBO36_RS04200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EBO36_RS04205	COG0601	transmembrane transport
EBO36_RS04210	COG1522	sequence-specific DNA binding
EBO36_RS04215	COG0444	Belongs to the ABC transporter superfamily
EBO36_RS04220	COG4608	Belongs to the ABC transporter superfamily
EBO36_RS04245	COG4166	transmembrane transport
EBO36_RS04260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBO36_RS04270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBO36_RS04275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EBO36_RS04295	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EBO36_RS04300	COG0066	3-isopropylmalate dehydratase activity
EBO36_RS04305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EBO36_RS04315	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EBO36_RS04325	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBO36_RS04340	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EBO36_RS04365	COG1461	Dihydroxyacetone kinase
EBO36_RS04375	COG4133	protoheme IX ABC transporter activity
EBO36_RS04390	COG0742	ribosomal rna small subunit methyltransferase
EBO36_RS04395	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EBO36_RS04410	COG0571	ribonuclease III activity
EBO36_RS04415	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EBO36_RS04430	COG1530	ribonuclease E activity
EBO36_RS04445	COG2154	pterin-4-alpha-carbinolamine dehydratase
EBO36_RS04470	COG0702	epimerase
EBO36_RS04475	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EBO36_RS04480	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EBO36_RS04485	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EBO36_RS04495	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EBO36_RS04500	COG1349	DNA-binding transcription factor activity
EBO36_RS04520	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EBO36_RS04525	COG1793	dna ligase
EBO36_RS04525	COG3285	dna ligase
EBO36_RS04530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EBO36_RS04535	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EBO36_RS04540	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EBO36_RS04550	COG0799	negative regulation of ribosome biogenesis
EBO36_RS04555	COG0588	phosphoglycerate mutase activity
EBO36_RS04585	COG1136	(ABC) transporter
EBO36_RS04585	COG0577	efflux transmembrane transporter activity
EBO36_RS04605	COG1404	Belongs to the peptidase S8 family
EBO36_RS04645	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EBO36_RS04685	COG0464	growth
EBO36_RS04765	COG1122	ATPase activity
EBO36_RS04770	COG3845	ABC transporter
EBO36_RS04780	COG0813	purine-nucleoside phosphorylase activity
EBO36_RS04790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBO36_RS04795	COG0318	PFAM AMP-dependent synthetase and ligase
EBO36_RS04800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EBO36_RS04825	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EBO36_RS04840	COG0435	Glutathione S-transferase
EBO36_RS04850	COG1228	amidohydrolase
EBO36_RS04880	COG1121	(ABC) transporter
EBO36_RS04885	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EBO36_RS04895	COG0537	adenosine 5'-monophosphoramidase activity
EBO36_RS04925	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EBO36_RS04930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EBO36_RS04935	COG0569	domain protein
EBO36_RS04945	COG0405	Gamma-glutamyltransferase
EBO36_RS04975	COG4585	Histidine kinase
EBO36_RS04980	COG2197	response regulator
EBO36_RS04995	COG0598	Magnesium transport protein CorA
EBO36_RS05000	COG0737	Belongs to the 5'-nucleotidase family
EBO36_RS05010	COG1175	transmembrane transport
EBO36_RS05015	COG0395	ABC-type sugar transport system, permease component
EBO36_RS05045	COG1609	Transcriptional regulator
EBO36_RS05055	COG0783	Belongs to the Dps family
EBO36_RS05060	COG0495	leucyl-tRNA aminoacylation
EBO36_RS05085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBO36_RS05095	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EBO36_RS05100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBO36_RS05105	COG1070	Carbohydrate kinase
EBO36_RS05110	COG1307	EDD domain protein, DegV family
EBO36_RS05140	COG0268	Binds directly to 16S ribosomal RNA
EBO36_RS05155	COG0481	GTPase activity
EBO36_RS05175	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EBO36_RS05185	COG0363	glucosamine-6-phosphate deaminase activity
EBO36_RS05215	COG1420	regulation of RNA biosynthetic process
EBO36_RS05220	COG0484	heat shock protein binding
EBO36_RS05235	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EBO36_RS05245	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EBO36_RS05260	COG1674	ftsk spoiiie
EBO36_RS05265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EBO36_RS05270	COG1381	Involved in DNA repair and RecF pathway recombination
EBO36_RS05275	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EBO36_RS05290	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EBO36_RS05295	COG1121	(ABC) transporter
EBO36_RS05300	COG0803	Belongs to the bacterial solute-binding protein 9 family
EBO36_RS05305	COG0423	glycine-tRNA ligase activity
EBO36_RS05320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EBO36_RS05325	COG2318	DinB family
EBO36_RS05345	COG0252	asparaginase activity
EBO36_RS05350	COG0366	Alpha amylase catalytic
EBO36_RS05360	COG2182	Extracellular solute-binding protein
EBO36_RS05365	COG1175	transmembrane transport
EBO36_RS05370	COG3833	ABC-type maltose transport systems, permease component
EBO36_RS05405	COG0596	Alpha beta hydrolase
EBO36_RS05410	COG0358	DNA primase activity
EBO36_RS05415	COG0154	amidase activity
EBO36_RS05440	COG0328	RNA-DNA hybrid ribonuclease activity
EBO36_RS05485	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EBO36_RS05495	COG4251	negative regulation of phosphorylation
EBO36_RS05510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EBO36_RS05515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EBO36_RS05520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EBO36_RS05550	COG0477	Major facilitator Superfamily
EBO36_RS05555	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EBO36_RS05600	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EBO36_RS05605	COG4988	ABC transporter
EBO36_RS05610	COG1294	oxidase, subunit
EBO36_RS05615	COG1271	oxidase subunit
EBO36_RS05650	COG1846	Transcriptional regulator
EBO36_RS05665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EBO36_RS05715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EBO36_RS05780	COG1793	dna ligase
EBO36_RS05805	COG2169	Transcriptional regulator
EBO36_RS05805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EBO36_RS05810	COG1595	DNA-templated transcription, initiation
EBO36_RS05815	COG2197	response regulator
EBO36_RS05830	COG1131	(ABC) transporter
EBO36_RS05845	COG2323	membrane
EBO36_RS05855	COG2514	catechol 2,3-dioxygenase activity
EBO36_RS05860	COG0215	cysteine-tRNA ligase activity
EBO36_RS05875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EBO36_RS05900	COG1222	aaa ATPase
EBO36_RS05915	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EBO36_RS05930	COG0107	imidazoleglycerol-phosphate synthase activity
EBO36_RS05945	COG1132	(ABC) transporter
EBO36_RS05950	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EBO36_RS05975	COG0134	indole-3-glycerol-phosphate synthase activity
EBO36_RS05980	COG0133	tryptophan synthase activity
EBO36_RS05995	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EBO36_RS06000	COG0069	glutamate synthase activity
EBO36_RS06000	COG0067	glutamate synthase
EBO36_RS06000	COG0070	glutamate synthase
EBO36_RS06035	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EBO36_RS06045	COG0640	Transcriptional regulator
EBO36_RS06055	COG1331	Highly conserved protein containing a thioredoxin domain
EBO36_RS06085	COG1937	Protein conserved in bacteria
EBO36_RS06090	COG0446	pyridine nucleotide-disulphide oxidoreductase
EBO36_RS06115	COG1063	alcohol dehydrogenase
EBO36_RS06125	COG1609	Transcriptional regulator
EBO36_RS06135	COG1175	transmembrane transport
EBO36_RS06140	COG0395	ABC-type sugar transport system, permease component
EBO36_RS06145	COG1472	Belongs to the glycosyl hydrolase 3 family
EBO36_RS06150	COG3340	Belongs to the peptidase S51 family
EBO36_RS06155	COG1228	amidohydrolase
EBO36_RS06160	COG4608	Belongs to the ABC transporter superfamily
EBO36_RS06165	COG0444	Belongs to the ABC transporter superfamily
EBO36_RS06170	COG1228	amidohydrolase
EBO36_RS06175	COG4166	transmembrane transport
EBO36_RS06180	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EBO36_RS06185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EBO36_RS06190	COG0601	transmembrane transport
EBO36_RS06195	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBO36_RS06205	COG0514	ATP-dependent DNA helicase (RecQ)
EBO36_RS06325	COG2050	protein possibly involved in aromatic compounds catabolism
EBO36_RS06335	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EBO36_RS06340	COG0205	6-phosphofructokinase activity
EBO36_RS06345	COG0539	negative regulation of cytoplasmic translation
EBO36_RS06360	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EBO36_RS06370	COG0237	dephospho-CoA kinase activity
EBO36_RS06370	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EBO36_RS06380	COG0556	nucleotide-excision repair
EBO36_RS06405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBO36_RS06430	COG0322	excinuclease ABC activity
EBO36_RS06435	COG1660	Displays ATPase and GTPase activities
EBO36_RS06440	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EBO36_RS06445	COG1481	regulation of sporulation
EBO36_RS06450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EBO36_RS06455	COG0126	phosphoglycerate kinase activity
EBO36_RS06460	COG0149	triose-phosphate isomerase activity
EBO36_RS06465	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EBO36_RS06480	COG0363	glucosamine-6-phosphate deaminase activity
EBO36_RS06495	COG0166	Belongs to the GPI family
EBO36_RS06500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EBO36_RS06510	COG0109	protoheme IX farnesyltransferase activity
EBO36_RS06525	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EBO36_RS06530	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EBO36_RS06550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBO36_RS06560	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EBO36_RS06570	COG1160	GTP binding
EBO36_RS06605	COG0604	alcohol dehydrogenase
EBO36_RS06665	COG0110	maltose O-acetyltransferase activity
EBO36_RS06725	COG0736	holo-[acyl-carrier-protein] synthase activity
EBO36_RS06745	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EBO36_RS06790	COG2367	Beta-lactamase
EBO36_RS06820	COG1733	regulation of RNA biosynthetic process
EBO36_RS06875	COG3340	Belongs to the peptidase S51 family
EBO36_RS06885	COG1136	(ABC) transporter
EBO36_RS06905	COG0702	epimerase
EBO36_RS06915	COG0515	serine threonine protein kinase
EBO36_RS06940	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EBO36_RS06945	COG0798	PFAM Bile acid sodium symporter
EBO36_RS06955	COG0640	Transcriptional regulator
EBO36_RS06990	COG0640	Transcriptional regulator
EBO36_RS07015	COG3507	Belongs to the glycosyl hydrolase 43 family
EBO36_RS07020	COG3507	Belongs to the glycosyl hydrolase 43 family
EBO36_RS07035	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EBO36_RS07040	COG0154	amidase activity
EBO36_RS07045	COG0673	inositol 2-dehydrogenase activity
EBO36_RS07060	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EBO36_RS07065	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EBO36_RS07100	COG1028	Short-chain dehydrogenase reductase Sdr
EBO36_RS07110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBO36_RS07120	COG1737	Transcriptional regulator
EBO36_RS07125	COG2182	Extracellular solute-binding protein
EBO36_RS07130	COG4149	molybdate abc transporter
EBO36_RS07140	COG4821	SIS domain
EBO36_RS07160	COG3844	kynureninase activity
EBO36_RS07165	COG0251	oxidation-reduction process
EBO36_RS07170	COG0179	Fumarylacetoacetate (FAA) hydrolase
EBO36_RS07185	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EBO36_RS07190	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EBO36_RS07195	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EBO36_RS07220	COG1131	(ABC) transporter
EBO36_RS07225	COG1309	transcriptional regulator
EBO36_RS07240	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EBO36_RS07250	COG2409	Drug exporters of the RND superfamily
EBO36_RS07260	COG0154	amidase activity
EBO36_RS07270	COG1129	ABC transporter
EBO36_RS07275	COG1172	Belongs to the binding-protein-dependent transport system permease family
EBO36_RS07280	COG1879	ABC-type sugar transport system periplasmic component
EBO36_RS07290	COG1609	Transcriptional regulator
EBO36_RS07300	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EBO36_RS07305	COG1984	allophanate hydrolase subunit 2
EBO36_RS07315	COG0205	6-phosphofructokinase activity
EBO36_RS07335	COG4821	SIS domain
EBO36_RS07350	COG0363	glucosamine-6-phosphate deaminase activity
EBO36_RS07365	COG0596	Alpha beta hydrolase
EBO36_RS07370	COG1357	PFAM Pentapeptide repeats (8 copies)
EBO36_RS07375	COG1902	pentaerythritol trinitrate reductase activity
EBO36_RS07380	COG1234	tRNA 3'-trailer cleavage
EBO36_RS07400	COG0318	PFAM AMP-dependent synthetase and ligase
EBO36_RS07420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EBO36_RS07425	COG0300	oxidoreductase activity
EBO36_RS07435	COG1643	Atp-dependent helicase
EBO36_RS07495	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EBO36_RS07500	COG1295	ribonuclease BN
EBO36_RS07510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBO36_RS07580	COG2813	Specifically methylates the guanine in position
EBO36_RS07590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EBO36_RS07630	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EBO36_RS07640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EBO36_RS07650	COG0829	nickel cation binding
EBO36_RS07655	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EBO36_RS07660	COG0830	nickel cation binding
EBO36_RS07665	COG0804	urea catabolic process
EBO36_RS07670	COG0832	Belongs to the urease beta subunit family
EBO36_RS07680	COG0831	urea catabolic process
EBO36_RS07685	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EBO36_RS07690	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EBO36_RS07705	COG0667	Aldo Keto reductase
EBO36_RS07715	COG1216	Glycosyl transferase, family 2
EBO36_RS07730	COG0805	protein transport
EBO36_RS07735	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBO36_RS07750	COG2378	regulation of single-species biofilm formation
EBO36_RS07785	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EBO36_RS07790	COG0140	phosphoribosyl-ATP diphosphatase activity
EBO36_RS07795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EBO36_RS07800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EBO36_RS07805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EBO36_RS07815	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EBO36_RS07825	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EBO36_RS07830	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EBO36_RS07840	COG1758	RNA polymerase activity
EBO36_RS07845	COG0194	GDP metabolic process
EBO36_RS07855	COG0284	orotidine-5'-phosphate decarboxylase activity
EBO36_RS07860	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EBO36_RS07865	COG0505	Belongs to the CarA family
EBO36_RS07870	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EBO36_RS07875	COG0540	Belongs to the ATCase OTCase family
EBO36_RS07880	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EBO36_RS07890	COG1404	Belongs to the peptidase S8 family
EBO36_RS07895	COG1058	Belongs to the CinA family
EBO36_RS07895	COG1546	Belongs to the CinA family
EBO36_RS07900	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EBO36_RS07905	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EBO36_RS07930	COG0733	neurotransmitter:sodium symporter activity
EBO36_RS07935	COG2318	DinB family
EBO36_RS07940	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EBO36_RS07945	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EBO36_RS07950	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EBO36_RS07955	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EBO36_RS07965	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EBO36_RS07970	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EBO36_RS07985	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EBO36_RS07995	COG2409	Drug exporters of the RND superfamily
EBO36_RS08005	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EBO36_RS08025	COG0124	histidyl-tRNA synthetase
EBO36_RS08040	COG1196	nuclear chromosome segregation
EBO36_RS08050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBO36_RS08055	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EBO36_RS08060	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EBO36_RS08065	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EBO36_RS08075	COG2255	four-way junction helicase activity
EBO36_RS08080	COG0632	four-way junction helicase activity
EBO36_RS08085	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EBO36_RS08090	COG0217	transcriptional regulatory protein
EBO36_RS08095	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EBO36_RS08110	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EBO36_RS08125	COG0438	transferase activity, transferring glycosyl groups
EBO36_RS08130	COG1560	Kdo2-lipid A biosynthetic process
EBO36_RS08135	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EBO36_RS08145	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EBO36_RS08160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EBO36_RS08165	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EBO36_RS08165	COG0512	Glutamine amidotransferase of anthranilate synthase
EBO36_RS08220	COG1090	epimerase
EBO36_RS08230	COG1063	alcohol dehydrogenase
EBO36_RS08240	COG3573	Dehydrogenase
EBO36_RS08300	COG1012	belongs to the aldehyde dehydrogenase family
EBO36_RS08300	COG1454	alcohol dehydrogenase
EBO36_RS08305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBO36_RS08310	COG2226	methyltransferase
EBO36_RS08340	COG1250	3-hydroxyacyl-CoA dehydrogenase
EBO36_RS08340	COG1024	Enoyl-CoA hydratase
EBO36_RS08355	COG1882	Formate acetyltransferase
EBO36_RS08370	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EBO36_RS08375	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EBO36_RS08380	COG0531	amino acid
EBO36_RS08385	COG0569	domain protein
EBO36_RS08405	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EBO36_RS08410	COG0756	dUTP diphosphatase activity
EBO36_RS08425	COG0483	inositol monophosphate 1-phosphatase activity
EBO36_RS08450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EBO36_RS08460	COG0456	acetyltransferase
EBO36_RS08460	COG0454	-acetyltransferase
EBO36_RS08465	COG0187	DNA topoisomerase II activity
EBO36_RS08505	COG0589	response to stress
EBO36_RS08515	COG0142	geranyltranstransferase activity
EBO36_RS08525	COG0741	lytic transglycosylase activity
EBO36_RS08530	COG2815	serine threonine protein kinase
EBO36_RS08530	COG0515	serine threonine protein kinase
EBO36_RS08540	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EBO36_RS08565	COG1940	carbohydrate kinase activity
EBO36_RS08590	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EBO36_RS08600	COG1845	cytochrome c oxidase, subunit III
EBO36_RS08605	COG2010	Cytochrome c
EBO36_RS08610	COG0723	plastoquinol--plastocyanin reductase activity
EBO36_RS08615	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EBO36_RS08635	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EBO36_RS08640	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EBO36_RS08665	COG0167	dihydroorotate dehydrogenase activity
EBO36_RS08680	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBO36_RS08690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EBO36_RS08695	COG0508	dehydrogenase complex catalyzes the overall conversion of
EBO36_RS08700	COG2807	transmembrane transport
EBO36_RS08715	COG2409	Drug exporters of the RND superfamily
EBO36_RS08725	COG0321	lipoyl(octanoyl) transferase activity
EBO36_RS08730	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EBO36_RS08755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EBO36_RS08770	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EBO36_RS08775	COG0174	glutamine synthetase
EBO36_RS08790	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBO36_RS08805	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EBO36_RS08805	COG1796	DNA polymerase
EBO36_RS08835	COG0395	ABC-type sugar transport system, permease component
EBO36_RS08855	COG0477	Major facilitator Superfamily
EBO36_RS08860	COG0657	acetylesterase activity
EBO36_RS08870	COG4941	Belongs to the sigma-70 factor family
EBO36_RS08885	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EBO36_RS08925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EBO36_RS08930	COG1125	glycine betaine transport
EBO36_RS08930	COG0517	IMP dehydrogenase activity
EBO36_RS08935	COG1174	glycine betaine transport
EBO36_RS08985	COG0252	asparaginase activity
EBO36_RS09035	COG1053	succinate dehydrogenase
EBO36_RS09070	COG3340	Belongs to the peptidase S51 family
EBO36_RS09075	COG2814	Major facilitator Superfamily
EBO36_RS09080	COG2814	Major facilitator Superfamily
EBO36_RS09105	COG1063	alcohol dehydrogenase
EBO36_RS09120	COG1063	alcohol dehydrogenase
EBO36_RS09125	COG2326	polyphosphate kinase activity
EBO36_RS09130	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EBO36_RS09135	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EBO36_RS09185	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EBO36_RS09210	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EBO36_RS09220	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EBO36_RS09260	COG0596	Alpha beta hydrolase
EBO36_RS09265	COG4941	Belongs to the sigma-70 factor family
EBO36_RS09270	COG3795	YCII-related domain
EBO36_RS09285	COG2815	serine threonine protein kinase
EBO36_RS09285	COG0515	serine threonine protein kinase
EBO36_RS09320	COG3718	enzyme involved in inositol metabolism
EBO36_RS09340	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EBO36_RS09350	COG1175	transmembrane transport
EBO36_RS09355	COG0395	ABC-type sugar transport system, permease component
EBO36_RS09360	COG3842	ATPase activity
EBO36_RS09365	COG0613	PHP domain protein
EBO36_RS09375	COG0673	inositol 2-dehydrogenase activity
EBO36_RS09390	COG2855	membrane
EBO36_RS09405	COG1968	undecaprenyl-diphosphatase activity
EBO36_RS09410	COG0667	Aldo Keto reductase
EBO36_RS09430	COG0339	signal peptide processing
EBO36_RS09435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EBO36_RS09440	COG1028	Short-chain dehydrogenase reductase Sdr
EBO36_RS09445	COG2133	pyrroloquinoline quinone binding
EBO36_RS09475	COG0587	DNA-directed DNA polymerase activity
EBO36_RS09480	COG1368	sulfuric ester hydrolase activity
EBO36_RS09485	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EBO36_RS09495	COG2223	nitrite transmembrane transporter activity
EBO36_RS09500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EBO36_RS09505	COG1881	PFAM PEBP family protein
EBO36_RS09525	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EBO36_RS09555	COG1119	ATPase activity
EBO36_RS09570	COG0297	glycogen (starch) synthase activity
EBO36_RS09595	COG1028	Short-chain dehydrogenase reductase Sdr
EBO36_RS09620	COG0488	(ABC) transporter
EBO36_RS09645	COG2151	metal-sulfur cluster biosynthetic enzyme
EBO36_RS09650	COG0822	iron-sulfur transferase activity
EBO36_RS09660	COG0396	ATPase activity
EBO36_RS09670	COG0719	Fe-S assembly protein
EBO36_RS09695	COG1612	heme a metabolic process
EBO36_RS09700	COG0494	nUDIX hydrolase
EBO36_RS09705	COG0504	CTP synthase activity
EBO36_RS09735	COG0497	DNA recombination
EBO36_RS09740	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EBO36_RS09750	COG0647	UMP catabolic process
EBO36_RS09775	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EBO36_RS09780	COG2094	Belongs to the DNA glycosylase MPG family
EBO36_RS09785	COG0165	Argininosuccinate lyase
EBO36_RS09790	COG0137	argininosuccinate synthase activity
EBO36_RS09795	COG1438	arginine binding
EBO36_RS09800	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EBO36_RS09810	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EBO36_RS09815	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EBO36_RS09820	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EBO36_RS09830	COG0300	oxidoreductase activity
EBO36_RS09835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EBO36_RS09835	COG0072	phenylalanine-tRNA ligase activity
EBO36_RS09840	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EBO36_RS09855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBO36_RS09860	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EBO36_RS09865	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EBO36_RS09870	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EBO36_RS09880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBO36_RS09890	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EBO36_RS09895	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EBO36_RS09905	COG0131	Imidazoleglycerol-phosphate dehydratase
EBO36_RS09910	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EBO36_RS09935	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EBO36_RS09940	COG2501	S4 domain
EBO36_RS09950	COG0587	DNA-directed DNA polymerase activity
EBO36_RS09955	COG2153	protein acetylation
EBO36_RS09965	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EBO36_RS09970	COG3599	regulation of cell shape
EBO36_RS09980	COG1799	cell septum assembly
EBO36_RS09985	COG1496	oxidoreductase activity
EBO36_RS09990	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EBO36_RS10000	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EBO36_RS10005	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EBO36_RS10015	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EBO36_RS10020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBO36_RS10025	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EBO36_RS10030	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EBO36_RS10035	COG0768	penicillin binding
EBO36_RS10045	COG0275	rRNA processing
EBO36_RS10050	COG2001	Belongs to the MraZ family
EBO36_RS10060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EBO36_RS10070	COG1278	Cold shock
EBO36_RS10080	COG0784	Response regulator, receiver
EBO36_RS10085	COG4251	negative regulation of phosphorylation
EBO36_RS10100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EBO36_RS10105	COG0667	Aldo Keto reductase
EBO36_RS10110	COG0318	PFAM AMP-dependent synthetase and ligase
EBO36_RS10115	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EBO36_RS10140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EBO36_RS10145	COG2813	Specifically methylates the guanine in position
EBO36_RS10150	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EBO36_RS10155	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EBO36_RS10160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EBO36_RS10165	COG1126	abc transporter atp-binding protein
EBO36_RS10170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EBO36_RS10175	COG0765	amino acid transport
EBO36_RS10180	COG0765	amino acid transport
EBO36_RS10185	COG2137	regulation of response to DNA damage stimulus
EBO36_RS10190	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EBO36_RS10200	COG1201	RNA secondary structure unwinding
EBO36_RS10205	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EBO36_RS10215	COG1546	Belongs to the CinA family
EBO36_RS10215	COG1058	Belongs to the CinA family
EBO36_RS10235	COG1674	ftsk spoiiie
EBO36_RS10240	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EBO36_RS10245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBO36_RS10260	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EBO36_RS10265	COG0612	Peptidase, M16
EBO36_RS10270	COG1185	polyribonucleotide nucleotidyltransferase activity
EBO36_RS10275	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EBO36_RS10285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EBO36_RS10290	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EBO36_RS10295	COG0730	response to heat
EBO36_RS10300	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EBO36_RS10305	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EBO36_RS10320	COG0779	Required for maturation of 30S ribosomal subunits
EBO36_RS10330	COG0442	prolyl-tRNA aminoacylation
EBO36_RS10335	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EBO36_RS10345	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EBO36_RS10350	COG0750	zinc metalloprotease
EBO36_RS10355	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EBO36_RS10365	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EBO36_RS10370	COG0575	Belongs to the CDS family
EBO36_RS10375	COG0233	cytoplasmic translational termination
EBO36_RS10385	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EBO36_RS10390	COG0052	Belongs to the universal ribosomal protein uS2 family
EBO36_RS10400	COG4974	Belongs to the 'phage' integrase family
EBO36_RS10415	COG0792	nuclease activity
EBO36_RS10425	COG1028	Short-chain dehydrogenase reductase Sdr
EBO36_RS10435	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EBO36_RS10445	COG0335	large ribosomal subunit rRNA binding
EBO36_RS10450	COG0336	Belongs to the RNA methyltransferase TrmD family
EBO36_RS10455	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EBO36_RS10465	COG1837	Belongs to the UPF0109 family
EBO36_RS10470	COG0228	four-way junction DNA binding
EBO36_RS10480	COG1131	(ABC) transporter
EBO36_RS10490	COG1131	(ABC) transporter
EBO36_RS10505	COG1609	Transcriptional regulator
EBO36_RS10520	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EBO36_RS10545	COG1196	nuclear chromosome segregation
EBO36_RS10550	COG0105	UTP biosynthetic process
EBO36_RS10565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBO36_RS10570	COG1461	Dihydroxyacetone kinase
EBO36_RS10575	COG2376	Dihydroxyacetone kinase
EBO36_RS10580	COG0285	dihydrofolate synthase activity
EBO36_RS10585	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EBO36_RS10595	COG2188	Transcriptional regulator
EBO36_RS10600	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EBO36_RS10635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EBO36_RS10640	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EBO36_RS10645	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
EBO36_RS10645	COG0778	Nitroreductase
EBO36_RS10650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBO36_RS10655	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EBO36_RS10670	COG1605	Chorismate mutase
EBO36_RS10670	COG0287	Prephenate dehydrogenase
EBO36_RS10680	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EBO36_RS10685	COG0740	serine-type endopeptidase activity
EBO36_RS10690	COG0740	serine-type endopeptidase activity
EBO36_RS10695	COG0544	peptidyl-prolyl cis-trans isomerase activity
EBO36_RS10710	COG0515	serine threonine protein kinase
EBO36_RS10730	COG1454	alcohol dehydrogenase
EBO36_RS10735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EBO36_RS10745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EBO36_RS10765	COG1739	Uncharacterized protein family UPF0029
EBO36_RS10785	COG1045	serine acetyltransferase
EBO36_RS10805	COG4552	Acetyltransferase involved in intracellular survival and related
EBO36_RS10815	COG3590	peptidase
EBO36_RS10825	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EBO36_RS10840	COG2190	(PTS) system
EBO36_RS10845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EBO36_RS10855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EBO36_RS10860	COG2188	Transcriptional regulator
EBO36_RS10865	COG1263	PTS System
EBO36_RS10875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBO36_RS10885	COG1946	Acyl-CoA thioesterase
EBO36_RS10890	COG4221	oxidoreductase activity
EBO36_RS10985	COG0154	amidase activity
EBO36_RS11010	COG0425	Belongs to the sulfur carrier protein TusA family
EBO36_RS11015	COG2391	methyltransferase activity
EBO36_RS11060	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EBO36_RS11065	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EBO36_RS11070	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EBO36_RS11075	COG1234	tRNA 3'-trailer cleavage
EBO36_RS11080	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EBO36_RS11090	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EBO36_RS11110	COG0363	glucosamine-6-phosphate deaminase activity
EBO36_RS11130	COG0667	Aldo Keto reductase
EBO36_RS11145	COG1131	(ABC) transporter
EBO36_RS11180	COG3386	PFAM SMP-30 Gluconolaconase
EBO36_RS11190	COG4948	Mandelate Racemase Muconate Lactonizing
EBO36_RS11195	COG1028	Short-chain dehydrogenase reductase Sdr
EBO36_RS11200	COG0395	ABC-type sugar transport system, permease component
EBO36_RS11205	COG1175	transmembrane transport
EBO36_RS11220	COG2186	Transcriptional regulator
EBO36_RS11225	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBO36_RS11235	COG0076	glutamate decarboxylase activity
EBO36_RS11255	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EBO36_RS11260	COG0739	heme binding
EBO36_RS11270	COG2884	Cell division ATP-binding protein ftsE
EBO36_RS11275	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EBO36_RS11285	COG2814	Major facilitator Superfamily
EBO36_RS11295	COG0477	Major facilitator Superfamily
EBO36_RS11300	COG0583	DNA-binding transcription factor activity
EBO36_RS11310	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EBO36_RS11315	COG2197	response regulator
EBO36_RS11320	COG4585	Histidine kinase
EBO36_RS11325	COG0586	Pfam SNARE associated Golgi protein
EBO36_RS11330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBO36_RS11400	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EBO36_RS11405	COG0154	amidase activity
EBO36_RS11410	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EBO36_RS11420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBO36_RS11425	COG2985	domain, Protein
EBO36_RS11425	COG0569	domain protein
EBO36_RS11445	COG1316	TRANSCRIPTIONal
EBO36_RS11450	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EBO36_RS11455	COG2135	peptidase activity
EBO36_RS11460	COG4585	Histidine kinase
EBO36_RS11465	COG2197	response regulator
EBO36_RS11470	COG0577	efflux transmembrane transporter activity
EBO36_RS11470	COG1136	(ABC) transporter
EBO36_RS11475	COG2177	Part of the ABC transporter FtsEX involved in
EBO36_RS11490	COG0586	Pfam SNARE associated Golgi protein
EBO36_RS11495	COG4632	Exopolysaccharide biosynthesis protein
EBO36_RS11495	COG5434	Belongs to the glycosyl hydrolase 28 family
EBO36_RS11515	COG0714	Associated with various cellular activities
EBO36_RS11525	COG1305	Transglutaminase-like
EBO36_RS11535	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EBO36_RS11550	COG0656	L-ascorbic acid biosynthetic process
EBO36_RS11560	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EBO36_RS11580	COG0714	Associated with various cellular activities
EBO36_RS11595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EBO36_RS11600	COG2354	Protein conserved in bacteria
EBO36_RS11610	COG3345	alpha-galactosidase
EBO36_RS11625	COG0395	ABC-type sugar transport system, permease component
EBO36_RS11630	COG1175	transmembrane transport
EBO36_RS11640	COG1940	carbohydrate kinase activity
EBO36_RS11650	COG1615	UPF0182 protein
EBO36_RS11665	COG3480	Lon protease (S16) C-terminal proteolytic domain
EBO36_RS11725	COG2890	protein-(glutamine-N5) methyltransferase activity
EBO36_RS11730	COG0210	DNA helicase
EBO36_RS11735	COG1074	ATP-dependent DNA helicase activity
EBO36_RS11755	COG2095	MarC family integral membrane protein
EBO36_RS11765	COG0006	proline dipeptidase activity
EBO36_RS11770	COG1082	Xylose isomerase domain protein TIM barrel
EBO36_RS11780	COG2239	Acts as a magnesium transporter
EBO36_RS11800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBO36_RS11810	COG1595	DNA-templated transcription, initiation
EBO36_RS11820	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBO36_RS11830	COG1611	Belongs to the LOG family
EBO36_RS11835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBO36_RS11865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EBO36_RS11875	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EBO36_RS11895	COG1725	Transcriptional regulator
EBO36_RS11910	COG1079	Belongs to the binding-protein-dependent transport system permease family
EBO36_RS11915	COG4603	Belongs to the binding-protein-dependent transport system permease family
EBO36_RS11920	COG3845	ABC transporter
EBO36_RS11925	COG1744	ABC transporter substrate-binding protein PnrA-like
EBO36_RS11930	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EBO36_RS11930	COG1473	amidohydrolase
EBO36_RS11945	COG1053	succinate dehydrogenase
EBO36_RS11950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EBO36_RS11960	COG1349	DNA-binding transcription factor activity
EBO36_RS11970	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EBO36_RS11980	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EBO36_RS11985	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EBO36_RS12010	COG1175	transmembrane transport
EBO36_RS12015	COG0395	ABC-type sugar transport system, permease component
EBO36_RS12040	COG0039	L-malate dehydrogenase activity
EBO36_RS12050	COG1253	flavin adenine dinucleotide binding
EBO36_RS12060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EBO36_RS12070	COG0138	bifunctional purine biosynthesis protein purh
EBO36_RS12085	COG0693	protein deglycase activity
EBO36_RS12105	COG0045	succinate-CoA ligase (ADP-forming) activity
EBO36_RS12110	COG2264	protein methyltransferase activity
EBO36_RS12115	COG2755	lipolytic protein G-D-S-L family
EBO36_RS12115	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EBO36_RS12140	COG2197	response regulator
EBO36_RS12175	COG0438	transferase activity, transferring glycosyl groups
EBO36_RS12180	COG0519	Catalyzes the synthesis of GMP from XMP
EBO36_RS12180	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBO36_RS12190	COG1132	(ABC) transporter
EBO36_RS12195	COG1132	(ABC) transporter
EBO36_RS12205	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EBO36_RS12215	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EBO36_RS12220	COG1027	Aspartate ammonia-lyase
EBO36_RS12225	COG0114	fumarate hydratase activity
EBO36_RS12230	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBO36_RS12235	COG0516	GMP reductase activity
EBO36_RS12255	COG0395	ABC-type sugar transport system, permease component
EBO36_RS12260	COG1175	transmembrane transport
EBO36_RS12270	COG1609	Transcriptional regulator
EBO36_RS12290	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EBO36_RS12300	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EBO36_RS12310	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EBO36_RS12330	COG0802	atpase or kinase
EBO36_RS12335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EBO36_RS12345	COG0736	holo-[acyl-carrier-protein] synthase activity
EBO36_RS12350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBO36_RS12355	COG1072	(Pantothenic acid kinase))
EBO36_RS12370	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EBO36_RS12375	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EBO36_RS12385	COG0101	tRNA pseudouridine synthase activity
EBO36_RS12395	COG0596	Alpha beta hydrolase
EBO36_RS12400	COG0203	ribosomal protein L17
EBO36_RS12405	COG0202	RNA polymerase activity
EBO36_RS12410	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EBO36_RS12415	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EBO36_RS12420	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EBO36_RS12425	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EBO36_RS12450	COG0563	adenylate kinase activity
EBO36_RS12455	COG0201	protein transport
EBO36_RS12460	COG0200	Binds to the 23S rRNA
EBO36_RS12465	COG1841	ribosomal large subunit assembly
EBO36_RS12470	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EBO36_RS12480	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EBO36_RS12485	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EBO36_RS12490	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EBO36_RS12495	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EBO36_RS12500	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EBO36_RS12505	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EBO36_RS12510	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EBO36_RS12515	COG0255	Belongs to the universal ribosomal protein uL29 family
EBO36_RS12520	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EBO36_RS12525	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EBO36_RS12530	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EBO36_RS12535	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EBO36_RS12540	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EBO36_RS12545	COG0089	rRNA binding
EBO36_RS12550	COG0088	Forms part of the polypeptide exit tunnel
EBO36_RS12555	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EBO36_RS12560	COG0051	transcription antitermination factor activity, RNA binding
EBO36_RS12565	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EBO36_RS12570	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EBO36_RS12575	COG0049	tRNA binding
EBO36_RS12580	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EBO36_RS12585	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EBO36_RS12590	COG0085	RNA polymerase activity
EBO36_RS12595	COG0222	ribosome binding
EBO36_RS12600	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EBO36_RS12605	COG0081	regulation of translation
EBO36_RS12610	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EBO36_RS12630	COG0436	Aminotransferase
EBO36_RS12640	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EBO36_RS12655	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EBO36_RS12660	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EBO36_RS12665	COG0113	porphobilinogen synthase activity
EBO36_RS12675	COG0181	hydroxymethylbilane synthase activity
EBO36_RS12685	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EBO36_RS12690	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EBO36_RS12695	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EBO36_RS12700	COG3253	May function as heme-dependent peroxidase
EBO36_RS12705	COG0738	Major facilitator superfamily
EBO36_RS12715	COG2030	dehydratase
EBO36_RS12720	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EBO36_RS12740	COG1666	GTP binding
EBO36_RS12755	COG0501	Belongs to the peptidase M48B family
EBO36_RS12765	COG0142	geranyltranstransferase activity
EBO36_RS12770	COG1007	ATP synthesis coupled electron transport
EBO36_RS12780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBO36_RS12785	COG0713	ATP synthesis coupled electron transport
EBO36_RS12790	COG0839	Belongs to the complex I subunit 6 family
EBO36_RS12800	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EBO36_RS12805	COG1034	ATP synthesis coupled electron transport
EBO36_RS12820	COG0649	NAD binding
EBO36_RS12825	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBO36_RS12830	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBO36_RS12845	COG2226	methyltransferase
EBO36_RS12850	COG1169	isochorismate synthase
EBO36_RS12855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBO36_RS12860	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EBO36_RS12865	COG4948	Mandelate Racemase Muconate Lactonizing
EBO36_RS12870	COG0640	Transcriptional regulator
EBO36_RS12880	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EBO36_RS12915	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EBO36_RS12920	COG1333	cytochrome c biogenesis protein
EBO36_RS12925	COG0785	Cytochrome C biogenesis protein
EBO36_RS12935	COG0406	alpha-ribazole phosphatase activity
EBO36_RS12975	COG0123	including yeast histone deacetylase and acetoin utilization protein
EBO36_RS12980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EBO36_RS12985	COG0569	domain protein
EBO36_RS12990	COG2160	L-arabinose isomerase activity
EBO36_RS13020	COG1172	Belongs to the binding-protein-dependent transport system permease family
EBO36_RS13030	COG1879	ABC-type sugar transport system periplasmic component
EBO36_RS13035	COG1609	Transcriptional regulator
EBO36_RS13040	COG2017	converts alpha-aldose to the beta-anomer
EBO36_RS13055	COG0395	ABC-type sugar transport system, permease component
EBO36_RS13060	COG1175	transmembrane transport
EBO36_RS13065	COG1653	transport
EBO36_RS13080	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EBO36_RS13085	COG3458	cephalosporin-C deacetylase activity
EBO36_RS13090	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EBO36_RS13100	COG1194	a g-specific adenine glycosylase
EBO36_RS13110	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EBO36_RS13125	COG0753	catalase activity
EBO36_RS13145	COG3250	beta-galactosidase activity
EBO36_RS13185	COG1609	Transcriptional regulator
EBO36_RS13195	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EBO36_RS13205	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EBO36_RS13210	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EBO36_RS13235	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EBO36_RS13245	COG0302	gtp cyclohydrolase
EBO36_RS13250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EBO36_RS13260	COG0037	tRNA processing
EBO36_RS13275	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EBO36_RS13285	COG3103	Sh3 type 3 domain protein
EBO36_RS13285	COG0791	NLP P60 protein
EBO36_RS13285	COG1388	LysM domain
EBO36_RS13290	COG2873	o-acetylhomoserine
EBO36_RS13295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBO36_RS13310	COG0247	lactate metabolic process
EBO36_RS13310	COG0277	FAD linked oxidase domain protein
EBO36_RS13315	COG0574	Belongs to the PEP-utilizing enzyme family
EBO36_RS13315	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBO36_RS13330	COG1131	(ABC) transporter
EBO36_RS13385	COG1490	D-aminoacyl-tRNA deacylase activity
EBO36_RS13400	COG0354	folic acid binding
EBO36_RS13405	COG3485	protocatechuate 3,4-dioxygenase
EBO36_RS13415	COG0745	RESPONSE REGULATOR receiver
EBO36_RS13425	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EBO36_RS13445	COG0406	alpha-ribazole phosphatase activity
EBO36_RS13445	COG0494	nUDIX hydrolase
EBO36_RS13450	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EBO36_RS13455	COG0456	acetyltransferase
EBO36_RS13530	COG0513	Belongs to the DEAD box helicase family
EBO36_RS13535	COG0492	ferredoxin-NADP+ reductase activity
EBO36_RS13540	COG2261	transglycosylase associated protein
EBO36_RS13550	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EBO36_RS13570	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EBO36_RS13580	COG1476	TRANSCRIPTIONal
EBO36_RS13610	COG1070	Carbohydrate kinase
EBO36_RS13615	COG1028	Short-chain dehydrogenase reductase Sdr
EBO36_RS13615	COG3347	Dehydrogenase
EBO36_RS13625	COG3254	rhamnose metabolic process
EBO36_RS13635	COG1172	Belongs to the binding-protein-dependent transport system permease family
EBO36_RS13640	COG1172	Belongs to the binding-protein-dependent transport system permease family
EBO36_RS13645	COG1129	ABC transporter
EBO36_RS13660	COG1136	(ABC) transporter
EBO36_RS13695	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EBO36_RS13705	COG0557	exoribonuclease II activity
EBO36_RS13725	COG0477	Major facilitator Superfamily
EBO36_RS13730	COG3142	Participates in the control of copper homeostasis
EBO36_RS13735	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EBO36_RS13740	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EBO36_RS13780	COG2030	dehydratase
EBO36_RS13790	COG0047	phosphoribosylformylglycinamidine synthase activity
EBO36_RS13795	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EBO36_RS13800	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EBO36_RS13805	COG0151	Belongs to the GarS family
EBO36_RS13815	COG1063	alcohol dehydrogenase
EBO36_RS13820	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EBO36_RS13855	COG1704	LemA family
EBO36_RS13860	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EBO36_RS13865	COG4221	oxidoreductase activity
EBO36_RS13885	COG0542	response to heat
EBO36_RS13905	COG1505	serine-type exopeptidase activity
EBO36_RS13915	COG0789	Transcriptional regulator
EBO36_RS13920	COG0484	heat shock protein binding
EBO36_RS13925	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EBO36_RS13930	COG0443	Heat shock 70 kDa protein
EBO36_RS13950	COG0745	RESPONSE REGULATOR receiver
EBO36_RS13955	COG2205	protein histidine kinase activity
EBO36_RS13960	COG0659	secondary active sulfate transmembrane transporter activity
EBO36_RS13965	COG1131	(ABC) transporter
EBO36_RS13990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EBO36_RS14020	COG0667	Aldo Keto reductase
EBO36_RS14025	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EBO36_RS14055	COG1136	(ABC) transporter
EBO36_RS14055	COG0577	efflux transmembrane transporter activity
EBO36_RS14080	COG0765	amino acid transport
EBO36_RS14090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EBO36_RS14140	COG3845	ABC transporter
EBO36_RS14150	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBO36_RS14160	COG0442	prolyl-tRNA aminoacylation
EBO36_RS14180	COG0596	Alpha beta hydrolase
EBO36_RS14190	COG3842	ATPase activity
EBO36_RS14210	COG1320	monovalent cation:proton antiporter activity
EBO36_RS14215	COG2212	antiporter activity
EBO36_RS14225	COG0651	ATP synthesis coupled electron transport
EBO36_RS14230	COG1006	Multisubunit Na H antiporter MnhC subunit
EBO36_RS14235	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBO36_RS14235	COG2111	Na H antiporter
EBO36_RS14240	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
EBO36_RS14265	COG0717	Belongs to the dCTP deaminase family
EBO36_RS14275	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EBO36_RS14280	COG1263	PTS System
EBO36_RS14280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EBO36_RS14280	COG2190	(PTS) system
EBO36_RS14285	COG3711	transcriptional antiterminator
EBO36_RS14290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBO36_RS14375	COG0714	Associated with various cellular activities
EBO36_RS14395	COG3537	Alpha-1,2-mannosidase
EBO36_RS14425	COG0823	Involved in the tonB-independent uptake of proteins
EBO36_RS14425	COG1506	peptidase
EBO36_RS14430	COG2208	phosphoserine phosphatase activity
EBO36_RS14430	COG2770	Histidine kinase
EBO36_RS14435	COG0508	dehydrogenase complex catalyzes the overall conversion of
EBO36_RS14440	COG0022	dehydrogenase e1 component
EBO36_RS14450	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EBO36_RS14455	COG1950	PFAM Membrane protein of
EBO36_RS14470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EBO36_RS14480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EBO36_RS14485	COG1937	Protein conserved in bacteria
EBO36_RS14505	COG2011	ABC-type metal ion transport system permease component
EBO36_RS14510	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EBO36_RS14545	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EBO36_RS14545	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EBO36_RS14550	COG0588	phosphoglycerate mutase activity
EBO36_RS14555	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EBO36_RS14565	COG1278	Cold shock
EBO36_RS14585	COG5006	permease, DMT superfamily
EBO36_RS14605	COG0640	Transcriptional regulator
EBO36_RS14655	COG2217	Heavy metal translocating P-type atpase
EBO36_RS14670	COG0351	phosphomethylpyrimidine kinase
EBO36_RS14685	COG1607	acyl-coa hydrolase
EBO36_RS14720	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EBO36_RS14725	COG1691	(AIR) carboxylase
EBO36_RS14730	COG1606	tRNA processing
EBO36_RS14735	COG1609	Transcriptional regulator
EBO36_RS14740	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EBO36_RS14750	COG1904	glucuronate isomerase
EBO36_RS14755	COG0246	Mannitol dehydrogenase
EBO36_RS14760	COG1070	Carbohydrate kinase
EBO36_RS14770	COG0384	phenazine biosynthesis protein PhzF
EBO36_RS14790	COG0616	signal peptide processing
EBO36_RS14825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EBO36_RS14840	COG4209	transmembrane transport
EBO36_RS14845	COG0395	ABC-type sugar transport system, permease component
EBO36_RS14850	COG0366	Alpha amylase catalytic
EBO36_RS14870	COG1476	TRANSCRIPTIONal
EBO36_RS14905	COG1116	anion transmembrane transporter activity
EBO36_RS14910	COG4585	Histidine kinase
EBO36_RS14930	COG4152	abc transporter atp-binding protein
EBO36_RS14955	COG0789	Transcriptional regulator
EBO36_RS14960	COG2814	Major facilitator Superfamily
EBO36_RS14965	COG1051	belongs to the nudix hydrolase family
EBO36_RS14965	COG1056	cytidyltransferase-related domain
EBO36_RS14970	COG0305	Participates in initiation and elongation during chromosome replication
EBO36_RS14975	COG0534	Mate efflux family protein
EBO36_RS14985	COG0359	binds to the 23S rRNA
EBO36_RS14990	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EBO36_RS15000	COG0360	Binds together with S18 to 16S ribosomal RNA
EBO36_RS15035	COG0617	tRNA 3'-terminal CCA addition
EBO36_RS15055	COG0492	ferredoxin-NADP+ reductase activity
EBO36_RS15060	COG3118	belongs to the thioredoxin family
EBO36_RS15065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EBO36_RS15070	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBO36_RS15075	COG0697	spore germination
EBO36_RS15080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EBO36_RS15090	COG1192	Involved in chromosome partitioning
EBO36_RS15095	COG0357	Ribosomal RNA small subunit methyltransferase G
EBO36_RS15105	COG0706	membrane insertase activity
EBO36_RS15110	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EBO36_RS15115	COG0594	ribonuclease P activity
EBO36_RS15120	COG0230	Belongs to the bacterial ribosomal protein bL34 family