locus-tag	class	description
Gferi_RS00015	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Gferi_RS00020	COG0539	negative regulation of cytoplasmic translation
Gferi_RS00020	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Gferi_RS00030	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Gferi_RS00040	COG2081	HI0933 family
Gferi_RS00065	COG1013	pyruvate-flavodoxin oxidoreductase activity
Gferi_RS00070	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Gferi_RS00070	COG0674	pyruvate-flavodoxin oxidoreductase activity
Gferi_RS00080	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Gferi_RS00095	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Gferi_RS00105	COG1187	pseudouridine synthase activity
Gferi_RS00120	COG1686	Belongs to the peptidase S11 family
Gferi_RS00130	COG3874	Sporulation protein YtfJ
Gferi_RS00140	COG1396	sequence-specific DNA binding
Gferi_RS00145	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Gferi_RS00150	COG0010	Belongs to the arginase family
Gferi_RS00155	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Gferi_RS00160	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Gferi_RS00165	COG1686	Belongs to the peptidase S11 family
Gferi_RS00175	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
Gferi_RS00180	COG4974	Belongs to the 'phage' integrase family
Gferi_RS00185	COG1300	Membrane
Gferi_RS00195	COG0733	neurotransmitter:sodium symporter activity
Gferi_RS00205	COG0463	Glycosyl transferase, family 2
Gferi_RS00225	COG0750	zinc metalloprotease
Gferi_RS00230	COG0497	DNA recombination
Gferi_RS00235	COG1438	arginine binding
Gferi_RS00240	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Gferi_RS00245	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Gferi_RS00260	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
Gferi_RS00270	COG1722	exodeoxyribonuclease VII activity
Gferi_RS00275	COG1570	exodeoxyribonuclease VII activity
Gferi_RS00280	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Gferi_RS00285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Gferi_RS00300	COG1302	Protein conserved in bacteria
Gferi_RS00340	COG3854	ATPases associated with a variety of cellular activities
Gferi_RS00350	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Gferi_RS00355	COG0006	proline dipeptidase activity
Gferi_RS00385	COG2199	diguanylate cyclase activity
Gferi_RS00385	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Gferi_RS00405	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Gferi_RS00440	COG1459	type II secretion system
Gferi_RS00450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Gferi_RS00455	COG1653	transport
Gferi_RS00470	COG0395	ABC-type sugar transport system, permease component
Gferi_RS00475	COG1175	transmembrane transport
Gferi_RS00495	COG5002	protein histidine kinase activity
Gferi_RS00500	COG0745	RESPONSE REGULATOR receiver
Gferi_RS00505	COG0726	polysaccharide deacetylase
Gferi_RS00510	COG1316	TRANSCRIPTIONal
Gferi_RS00525	COG0745	RESPONSE REGULATOR receiver
Gferi_RS00530	COG5002	protein histidine kinase activity
Gferi_RS00535	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Gferi_RS00540	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Gferi_RS00560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Gferi_RS00570	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
Gferi_RS00570	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Gferi_RS00575	COG0446	pyridine nucleotide-disulphide oxidoreductase
Gferi_RS00575	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Gferi_RS00585	COG0733	neurotransmitter:sodium symporter activity
Gferi_RS00595	COG0017	Asparaginyl-tRNA synthetase
Gferi_RS00600	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Gferi_RS00610	COG0613	PHP domain protein
Gferi_RS00615	COG2359	stage V sporulation protein S
Gferi_RS00620	COG1418	mRNA catabolic process
Gferi_RS00630	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Gferi_RS00635	COG1546	Belongs to the CinA family
Gferi_RS00635	COG1058	Belongs to the CinA family
Gferi_RS00640	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Gferi_RS00645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Gferi_RS00650	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
Gferi_RS00655	COG1674	ftsk spoiiie
Gferi_RS00660	COG0740	serine-type endopeptidase activity
Gferi_RS00665	COG0527	aspartate kinase activity
Gferi_RS00675	COG0756	dUTP diphosphatase activity
Gferi_RS00680	COG0612	Peptidase, M16
Gferi_RS00685	COG0726	polysaccharide deacetylase
Gferi_RS00690	COG1185	polyribonucleotide nucleotidyltransferase activity
Gferi_RS00695	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Gferi_RS00700	COG0196	riboflavin kinase activity
Gferi_RS00705	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Gferi_RS00710	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Gferi_RS00715	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Gferi_RS00720	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Gferi_RS00730	COG2740	Nucleic-acid-binding protein implicated in transcription termination
Gferi_RS00735	COG0195	Participates in both transcription termination and antitermination
Gferi_RS00740	COG0779	Required for maturation of 30S ribosomal subunits
Gferi_RS00755	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Gferi_RS00760	COG0750	zinc metalloprotease
Gferi_RS00765	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Gferi_RS00770	COG4589	Belongs to the CDS family
Gferi_RS00785	COG0233	cytoplasmic translational termination
Gferi_RS00790	COG0528	UMP kinase activity
Gferi_RS00795	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Gferi_RS00800	COG0052	Belongs to the universal ribosomal protein uS2 family
Gferi_RS00825	COG1191	sigma factor activity
Gferi_RS00835	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Gferi_RS00840	COG1776	CheC inhibitor of MCP methylation
Gferi_RS00845	COG0835	chemotaxis
Gferi_RS00850	COG2198	Histidine kinase
Gferi_RS00850	COG0643	Histidine kinase
Gferi_RS00855	COG2201	protein-glutamate methylesterase activity
Gferi_RS00870	COG1419	protein localization to endoplasmic reticulum
Gferi_RS00875	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Gferi_RS00880	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Gferi_RS00885	COG1684	flagellar biosynthetic protein fliR
Gferi_RS00890	COG1987	bacterial-type flagellum assembly
Gferi_RS00895	COG1338	Plays a role in the flagellum-specific transport system
Gferi_RS00905	COG2201	protein-glutamate methylesterase activity
Gferi_RS00910	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Gferi_RS00910	COG1776	CheC inhibitor of MCP methylation
Gferi_RS00915	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Gferi_RS00925	COG1360	Flagellar Motor Protein
Gferi_RS00950	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Gferi_RS00970	COG1157	protein secretion by the type III secretion system
Gferi_RS00980	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Gferi_RS00985	COG1766	The M ring may be actively involved in energy transduction
Gferi_RS00990	COG1677	Flagellar hook-basal body complex protein FliE
Gferi_RS00995	COG1558	bacterial-type flagellum-dependent cell motility
Gferi_RS01000	COG1815	bacterial-type flagellum-dependent cell motility
Gferi_RS01010	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Gferi_RS01020	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Gferi_RS01025	COG0758	DNA mediated transformation
Gferi_RS01030	COG0606	chelatase, subunit chli
Gferi_RS01140	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Gferi_RS01285	COG1361	Conserved repeat domain
Gferi_RS01390	COG0739	heme binding
Gferi_RS01445	COG1396	sequence-specific DNA binding
Gferi_RS01465	COG0606	chelatase, subunit chli
Gferi_RS01470	COG0792	nuclease activity
Gferi_RS01485	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Gferi_RS01500	COG0335	large ribosomal subunit rRNA binding
Gferi_RS01505	COG0336	Belongs to the RNA methyltransferase TrmD family
Gferi_RS01510	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Gferi_RS01515	COG1837	Belongs to the UPF0109 family
Gferi_RS01520	COG0228	four-way junction DNA binding
Gferi_RS01525	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Gferi_RS01535	COG0552	protein localization to endoplasmic reticulum
Gferi_RS01540	COG1196	nuclear chromosome segregation
Gferi_RS01545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Gferi_RS01550	COG0571	ribonuclease III activity
Gferi_RS01555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Gferi_RS01560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Gferi_RS01565	COG1028	Short-chain dehydrogenase reductase Sdr
Gferi_RS01570	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Gferi_RS01580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Gferi_RS01585	COG0416	fatty acid biosynthetic process
Gferi_RS01590	COG2030	dehydratase
Gferi_RS01595	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Gferi_RS01605	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Gferi_RS01610	COG1323	Belongs to the UPF0348 family
Gferi_RS01615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Gferi_RS01620	COG3314	Sporulation integral membrane protein YlbJ
Gferi_RS01630	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Gferi_RS01635	COG0742	ribosomal rna small subunit methyltransferase
Gferi_RS01645	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Gferi_RS01650	COG1461	Dihydroxyacetone kinase
Gferi_RS01655	COG1302	Protein conserved in bacteria
Gferi_RS01660	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Gferi_RS01670	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Gferi_RS01675	COG1162	GTPase activity
Gferi_RS01680	COG0515	serine threonine protein kinase
Gferi_RS01680	COG2815	serine threonine protein kinase
Gferi_RS01685	COG0631	protein serine/threonine phosphatase activity
Gferi_RS01690	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Gferi_RS01690	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Gferi_RS01695	COG2738	Putative neutral zinc metallopeptidase
Gferi_RS01705	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Gferi_RS01710	COG0242	peptide deformylase activity
Gferi_RS01715	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Gferi_RS01720	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Gferi_RS01725	COG1758	RNA polymerase activity
Gferi_RS01730	COG0194	GDP metabolic process
Gferi_RS01735	COG2052	Domain of unknown function (DUF370)
Gferi_RS01740	COG1561	YicC-like family, N-terminal region
Gferi_RS01745	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Gferi_RS01750	COG1293	RNA-binding protein homologous to eukaryotic snRNP
Gferi_RS01760	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Gferi_RS01765	COG0564	pseudouridine synthase activity
Gferi_RS01770	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Gferi_RS01780	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Gferi_RS01790	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Gferi_RS01795	COG3599	regulation of cell shape
Gferi_RS01800	COG2302	S4 RNA-binding domain
Gferi_RS01805	COG0762	integral membrane protein
Gferi_RS01810	COG1799	cell septum assembly
Gferi_RS01815	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Gferi_RS01835	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Gferi_RS01840	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Gferi_RS01845	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Gferi_RS01850	COG1160	GTP binding
Gferi_RS01870	COG0704	Plays a role in the regulation of phosphate uptake
Gferi_RS01875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Gferi_RS01885	COG0745	RESPONSE REGULATOR receiver
Gferi_RS01890	COG1496	oxidoreductase activity
Gferi_RS01895	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Gferi_RS01900	COG1873	PFAM PRC-barrel domain
Gferi_RS01905	COG1191	sigma factor activity
Gferi_RS01910	COG1191	sigma factor activity
Gferi_RS01920	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Gferi_RS01925	COG3856	small basic protein
Gferi_RS01945	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Gferi_RS01950	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Gferi_RS01955	COG0772	Belongs to the SEDS family
Gferi_RS01960	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Gferi_RS01965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Gferi_RS01970	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Gferi_RS01975	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Gferi_RS01980	COG0768	penicillin binding
Gferi_RS01990	COG0275	rRNA processing
Gferi_RS01995	COG2001	Belongs to the MraZ family
Gferi_RS02000	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Gferi_RS02005	COG0612	Peptidase, M16
Gferi_RS02010	COG0612	Peptidase, M16
Gferi_RS02025	COG0012	GTP binding
Gferi_RS02030	COG0706	membrane insertase activity
Gferi_RS02045	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Gferi_RS02050	COG4869	propanediol catabolic process
Gferi_RS02055	COG0011	TIGRFAM Protein of
Gferi_RS02075	COG1592	Rubrerythrin
Gferi_RS02075	COG1773	rubredoxin
Gferi_RS02085	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Gferi_RS02090	COG2096	Adenosyltransferase
Gferi_RS02125	COG0513	Belongs to the DEAD box helicase family
Gferi_RS02165	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Gferi_RS02170	COG2384	SAM-dependent methyltransferase
Gferi_RS02185	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Gferi_RS02190	COG0358	DNA primase activity
Gferi_RS02195	COG1671	Belongs to the UPF0178 family
Gferi_RS02200	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Gferi_RS02210	COG0574	Belongs to the PEP-utilizing enzyme family
Gferi_RS02210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Gferi_RS02215	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Gferi_RS02220	COG0517	IMP dehydrogenase activity
Gferi_RS02225	COG0423	glycine-tRNA ligase activity
Gferi_RS02230	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Gferi_RS02235	COG1381	Involved in DNA repair and RecF pathway recombination
Gferi_RS02240	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Gferi_RS02245	COG0295	cytidine deaminase activity
Gferi_RS02255	COG4536	flavin adenine dinucleotide binding
Gferi_RS02260	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Gferi_RS02265	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Gferi_RS02270	COG1480	7TM receptor with intracellular HD hydrolase
Gferi_RS02275	COG1702	phosphate starvation-inducible protein PhoH
Gferi_RS02295	COG4864	UPF0365 protein
Gferi_RS02300	COG1030	water channel activity
Gferi_RS02305	COG3568	Endonuclease Exonuclease Phosphatase
Gferi_RS02310	COG1610	YqeY-like protein
Gferi_RS02315	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Gferi_RS02320	COG0537	adenosine 5'-monophosphoramidase activity
Gferi_RS02325	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Gferi_RS02330	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Gferi_RS02335	COG2264	protein methyltransferase activity
Gferi_RS02340	COG0484	heat shock protein binding
Gferi_RS02345	COG0443	Heat shock 70 kDa protein
Gferi_RS02350	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Gferi_RS02355	COG0459	protein refolding
Gferi_RS02360	COG1420	regulation of RNA biosynthetic process
Gferi_RS02365	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Gferi_RS02370	COG0481	GTPase activity
Gferi_RS02380	COG0860	N-Acetylmuramoyl-L-alanine amidase
Gferi_RS02385	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Gferi_RS02390	COG0268	Binds directly to 16S ribosomal RNA
Gferi_RS02395	COG1466	dna polymerase III delta subunit
Gferi_RS02400	COG2333	competence protein COMEC
Gferi_RS02400	COG0658	competence protein
Gferi_RS02415	COG1234	tRNA 3'-trailer cleavage
Gferi_RS02425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Gferi_RS02430	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Gferi_RS02500	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Gferi_RS02505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Gferi_RS02510	COG1757	Na H antiporter
Gferi_RS02530	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Gferi_RS02530	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Gferi_RS02535	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Gferi_RS02540	COG2197	response regulator
Gferi_RS02545	COG2972	Histidine kinase
Gferi_RS02550	COG2721	sulfolactate sulfo-lyase activity
Gferi_RS02555	COG1904	glucuronate isomerase
Gferi_RS02560	COG0246	Mannitol dehydrogenase
Gferi_RS02565	COG1609	Transcriptional regulator
Gferi_RS02575	COG1280	lysine exporter protein (LysE YggA)
Gferi_RS02580	COG1522	sequence-specific DNA binding
Gferi_RS02600	COG4191	Histidine kinase
Gferi_RS02605	COG0784	Response regulator, receiver
Gferi_RS02610	COG0786	glutamate:sodium symporter activity
Gferi_RS02615	COG0460	homoserine dehydrogenase
Gferi_RS02635	COG1805	sodium ion transport
Gferi_RS02645	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Gferi_RS02660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Gferi_RS02665	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Gferi_RS02670	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Gferi_RS02670	COG0438	transferase activity, transferring glycosyl groups
Gferi_RS02675	COG0671	phosphoesterase, PA-phosphatase related
Gferi_RS02690	COG3238	Protein conserved in bacteria
Gferi_RS02695	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Gferi_RS02700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Gferi_RS02705	COG0730	response to heat
Gferi_RS02720	COG1739	Uncharacterized protein family UPF0029
Gferi_RS02740	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Gferi_RS02805	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Gferi_RS02815	COG0643	Histidine kinase
Gferi_RS02815	COG2198	Histidine kinase
Gferi_RS02830	COG1447	Phosphotransferase system cellobiose-specific component IIA
Gferi_RS02835	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Gferi_RS02845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Gferi_RS02850	COG1446	asparaginase
Gferi_RS02855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Gferi_RS02855	COG3711	transcriptional antiterminator
Gferi_RS02870	COG1686	Belongs to the peptidase S11 family
Gferi_RS02875	COG5002	protein histidine kinase activity
Gferi_RS02885	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Gferi_RS02890	COG1181	Belongs to the D-alanine--D-alanine ligase family
Gferi_RS02905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Gferi_RS02925	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Gferi_RS02930	COG1063	alcohol dehydrogenase
Gferi_RS02945	COG1592	Rubrerythrin
Gferi_RS02950	COG2205	protein histidine kinase activity
Gferi_RS02960	COG2986	histidine ammonia-lyase
Gferi_RS02965	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Gferi_RS02980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Gferi_RS02995	COG0534	Mate efflux family protein
Gferi_RS03000	COG2707	UPF0756 membrane protein
Gferi_RS03005	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
Gferi_RS03010	COG0310	cobalt ion transport
Gferi_RS03025	COG1122	ATPase activity
Gferi_RS03045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Gferi_RS03070	COG2172	sigma factor antagonist activity
Gferi_RS03080	COG1950	PFAM Membrane protein of
Gferi_RS03085	COG0301	tRNA thio-modification
Gferi_RS03125	COG2176	DNA-directed DNA polymerase activity
Gferi_RS03295	COG2211	Major facilitator Superfamily
Gferi_RS03305	COG5012	cobalamin binding
Gferi_RS03315	COG3829	transcription factor binding
Gferi_RS03325	COG3290	protein histidine kinase activity
Gferi_RS03335	COG0426	domain, Protein
Gferi_RS03345	COG0187	DNA topoisomerase II activity
Gferi_RS03350	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Gferi_RS03360	COG0006	proline dipeptidase activity
Gferi_RS03370	COG1760	l-serine dehydratase
Gferi_RS03375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Gferi_RS03390	COG1802	Transcriptional regulator
Gferi_RS03395	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Gferi_RS03400	COG1473	amidohydrolase
Gferi_RS03405	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Gferi_RS03410	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Gferi_RS03415	COG0006	proline dipeptidase activity
Gferi_RS03420	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Gferi_RS03425	COG0251	oxidation-reduction process
Gferi_RS03430	COG1414	Transcriptional regulator
Gferi_RS03445	COG3842	ATPase activity
Gferi_RS03450	COG1175	transmembrane transport
Gferi_RS03505	COG1199	ATP-dependent helicase activity
Gferi_RS03520	COG3655	Transcriptional regulator
Gferi_RS03535	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Gferi_RS03560	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Gferi_RS03565	COG0706	membrane insertase activity
Gferi_RS03580	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Gferi_RS03585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Gferi_RS03625	COG2873	o-acetylhomoserine
Gferi_RS03705	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Gferi_RS03775	COG0551	DNA topoisomerase type I activity
Gferi_RS03775	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Gferi_RS03795	COG0739	heme binding
Gferi_RS03860	COG1192	Involved in chromosome partitioning
Gferi_RS03970	COG0280	phosphate acetyltransferase
Gferi_RS03985	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Gferi_RS04015	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Gferi_RS04020	COG0018	arginyl-trna synthetase
Gferi_RS04025	COG0705	Rhomboid family
Gferi_RS04025	COG0457	Tetratricopeptide repeat
Gferi_RS04035	COG1683	Conserved Protein
Gferi_RS04045	COG1193	negative regulation of DNA recombination
Gferi_RS04050	COG0826	peptidase U32
Gferi_RS04055	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
Gferi_RS04060	COG0072	phenylalanine-tRNA ligase activity
Gferi_RS04060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Gferi_RS04065	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Gferi_RS04070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Gferi_RS04075	COG0569	domain protein
Gferi_RS04080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Gferi_RS04085	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Gferi_RS04095	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Gferi_RS04100	COG4214	carbohydrate transport
Gferi_RS04105	COG1079	Belongs to the binding-protein-dependent transport system permease family
Gferi_RS04115	COG1609	Transcriptional regulator
Gferi_RS04125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Gferi_RS04135	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Gferi_RS04140	COG4399	Belongs to the UPF0754 family
Gferi_RS04180	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Gferi_RS04190	COG2226	methyltransferase
Gferi_RS04195	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Gferi_RS04200	COG2135	peptidase activity
Gferi_RS04220	COG1473	amidohydrolase
Gferi_RS04225	COG1349	DNA-binding transcription factor activity
Gferi_RS04230	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Gferi_RS04240	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Gferi_RS04245	COG2171	N-acyltransferase activity
Gferi_RS04255	COG3681	Belongs to the UPF0597 family
Gferi_RS04260	COG3829	transcription factor binding
Gferi_RS04285	COG0733	neurotransmitter:sodium symporter activity
Gferi_RS04290	COG0726	polysaccharide deacetylase
Gferi_RS04295	COG1283	sodium-dependent phosphate transmembrane transporter activity
Gferi_RS04310	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Gferi_RS04340	COG0525	valine-tRNA ligase activity
Gferi_RS04365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Gferi_RS04380	COG2378	regulation of single-species biofilm formation
Gferi_RS04390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Gferi_RS04395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Gferi_RS04405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Gferi_RS04405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Gferi_RS04405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Gferi_RS04415	COG1349	DNA-binding transcription factor activity
Gferi_RS04445	COG2195	Cleaves the N-terminal amino acid of tripeptides
Gferi_RS04455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Gferi_RS04465	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Gferi_RS04470	COG1349	DNA-binding transcription factor activity
Gferi_RS04475	COG0561	phosphatase activity
Gferi_RS04480	COG0673	inositol 2-dehydrogenase activity
Gferi_RS04485	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Gferi_RS04490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Gferi_RS04500	COG3711	transcriptional antiterminator
Gferi_RS04505	COG1882	Formate acetyltransferase
Gferi_RS04510	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Gferi_RS04515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Gferi_RS04520	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Gferi_RS04525	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Gferi_RS04535	COG5598	trimethylamine methyltransferase
Gferi_RS04560	COG5012	cobalamin binding
Gferi_RS04570	COG3829	transcription factor binding
Gferi_RS04580	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Gferi_RS04585	COG2086	electron transfer activity
Gferi_RS04595	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Gferi_RS04600	COG2086	electron transfer activity
Gferi_RS04605	COG0277	FAD linked oxidase domain protein
Gferi_RS04610	COG1070	Carbohydrate kinase
Gferi_RS04615	COG1028	Short-chain dehydrogenase reductase Sdr
Gferi_RS04620	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
Gferi_RS04630	COG2155	Conserved Protein
Gferi_RS04650	COG0840	transmembrane signaling receptor activity
Gferi_RS04660	COG2959	enzyme of heme biosynthesis
Gferi_RS04670	COG0426	domain, Protein
Gferi_RS04685	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Gferi_RS04695	COG0243	molybdopterin cofactor binding
Gferi_RS04700	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
Gferi_RS04715	COG1116	anion transmembrane transporter activity
Gferi_RS04720	COG2323	membrane
Gferi_RS04735	COG1595	DNA-templated transcription, initiation
Gferi_RS04745	COG1116	anion transmembrane transporter activity
Gferi_RS04750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Gferi_RS04755	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Gferi_RS04755	COG0456	acetyltransferase
Gferi_RS04775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Gferi_RS04820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Gferi_RS04850	COG0412	Dienelactone hydrolase
Gferi_RS04890	COG2274	protein secretion by the type I secretion system
Gferi_RS04895	COG2274	protein secretion by the type I secretion system
Gferi_RS04920	COG2197	response regulator
Gferi_RS04925	COG4585	Histidine kinase
Gferi_RS04955	COG0517	IMP dehydrogenase activity
Gferi_RS04960	COG4974	Belongs to the 'phage' integrase family
Gferi_RS04975	COG0488	(ABC) transporter
Gferi_RS04980	COG0500	methyltransferase
Gferi_RS05010	COG1473	amidohydrolase
Gferi_RS05015	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
Gferi_RS05025	COG0613	PHP domain protein
Gferi_RS05035	COG1917	Cupin 2, conserved barrel domain protein
Gferi_RS05035	COG2207	Transcriptional regulator
Gferi_RS05055	COG1695	Transcriptional regulator
Gferi_RS05075	COG1846	Transcriptional regulator
Gferi_RS05075	COG0456	acetyltransferase
Gferi_RS05125	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Gferi_RS05145	COG0587	DNA-directed DNA polymerase activity
Gferi_RS05155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Gferi_RS05185	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
Gferi_RS05250	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Gferi_RS05255	COG1151	hydroxylamine reductase activity
Gferi_RS05260	COG1151	hydroxylamine reductase activity
Gferi_RS05265	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
Gferi_RS05270	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Gferi_RS05270	COG2199	diguanylate cyclase activity
Gferi_RS05280	COG1053	succinate dehydrogenase
Gferi_RS05295	COG4585	Histidine kinase
Gferi_RS05300	COG1132	(ABC) transporter
Gferi_RS05305	COG1132	(ABC) transporter
Gferi_RS05315	COG0569	domain protein
Gferi_RS05335	COG2188	Transcriptional regulator
Gferi_RS05360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Gferi_RS05365	COG0426	domain, Protein
Gferi_RS05385	COG5002	protein histidine kinase activity
Gferi_RS05390	COG0745	RESPONSE REGULATOR receiver
Gferi_RS05395	COG0569	domain protein
Gferi_RS05400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Gferi_RS05405	COG0569	domain protein
Gferi_RS05410	COG0569	domain protein
Gferi_RS05415	COG2204	response regulator
Gferi_RS05420	COG0745	RESPONSE REGULATOR receiver
Gferi_RS05425	COG5002	protein histidine kinase activity
Gferi_RS05430	COG2340	Cysteine-rich secretory protein family
Gferi_RS05445	COG0726	polysaccharide deacetylase
Gferi_RS05455	COG1619	proteins homologs of microcin C7 resistance protein MccF
Gferi_RS05460	COG0700	Nucleoside recognition
Gferi_RS05465	COG2715	membrane protein required for spore maturation
Gferi_RS05470	COG0019	diaminopimelate decarboxylase activity
Gferi_RS05475	COG3290	protein histidine kinase activity
Gferi_RS05475	COG3829	transcription factor binding
Gferi_RS05480	COG3858	chitin binding
Gferi_RS05490	COG2861	carbohydrate metabolic process
Gferi_RS05495	COG0814	amino acid
Gferi_RS05510	COG0697	spore germination
Gferi_RS05515	COG1132	(ABC) transporter
Gferi_RS05520	COG1132	(ABC) transporter
Gferi_RS05530	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Gferi_RS05535	COG1051	belongs to the nudix hydrolase family
Gferi_RS05545	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Gferi_RS05560	COG0028	Belongs to the TPP enzyme family
Gferi_RS05565	COG0129	dihydroxy-acid dehydratase activity
Gferi_RS05570	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Gferi_RS05615	COG1376	ErfK ybiS ycfS ynhG family protein
Gferi_RS05625	COG0564	pseudouridine synthase activity
Gferi_RS05630	COG0494	nUDIX hydrolase
Gferi_RS05635	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Gferi_RS05640	COG1301	dicarboxylic acid transport
Gferi_RS05645	COG0784	Response regulator, receiver
Gferi_RS05650	COG4191	Histidine kinase
Gferi_RS05680	COG3290	protein histidine kinase activity
Gferi_RS05685	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Gferi_RS05695	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Gferi_RS05700	COG0768	penicillin binding
Gferi_RS05705	COG0772	Belongs to the SEDS family
Gferi_RS05720	COG1164	Oligoendopeptidase f
Gferi_RS05730	COG2878	Part of a membrane complex involved in electron transport
Gferi_RS05735	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Gferi_RS05755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Gferi_RS05760	COG0589	response to stress
Gferi_RS05765	COG0628	permease
Gferi_RS05790	COG0668	transmembrane transport
Gferi_RS05795	COG1122	ATPase activity
Gferi_RS05810	COG0310	cobalt ion transport
Gferi_RS05825	COG1592	Rubrerythrin
Gferi_RS05825	COG1773	rubredoxin
Gferi_RS05830	COG1321	iron dependent repressor
Gferi_RS05835	COG0189	ligase activity
Gferi_RS05835	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Gferi_RS05855	COG1522	sequence-specific DNA binding
Gferi_RS05855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Gferi_RS05860	COG2313	pseudouridylate synthase activity
Gferi_RS05870	COG1619	proteins homologs of microcin C7 resistance protein MccF
Gferi_RS05875	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Gferi_RS05885	COG0494	nUDIX hydrolase
Gferi_RS05890	COG0667	Aldo Keto reductase
Gferi_RS05930	COG2204	response regulator
Gferi_RS05935	COG5002	protein histidine kinase activity
Gferi_RS05950	COG2226	methyltransferase
Gferi_RS05960	COG2132	Multicopper oxidase
Gferi_RS06055	COG2205	protein histidine kinase activity
Gferi_RS06060	COG0745	RESPONSE REGULATOR receiver
Gferi_RS06065	COG1522	sequence-specific DNA binding
Gferi_RS06070	COG1522	sequence-specific DNA binding
Gferi_RS06075	COG0535	radical SAM domain protein
Gferi_RS06080	COG0535	radical SAM domain protein
Gferi_RS06090	COG0175	sulfate reduction
Gferi_RS06100	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Gferi_RS06105	COG0529	Catalyzes the synthesis of activated sulfate
Gferi_RS06110	COG0471	metal ion transport
Gferi_RS06120	COG2873	o-acetylhomoserine
Gferi_RS06135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Gferi_RS06155	COG2204	response regulator
Gferi_RS06160	COG3852	Histidine kinase
Gferi_RS06175	COG2738	Putative neutral zinc metallopeptidase
Gferi_RS06185	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Gferi_RS06205	COG1937	Protein conserved in bacteria
Gferi_RS06210	COG2217	Heavy metal translocating P-type atpase
Gferi_RS06230	COG1126	abc transporter atp-binding protein
Gferi_RS06235	COG0686	Belongs to the AlaDH PNT family
Gferi_RS06240	COG1757	Na H antiporter
Gferi_RS06245	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
Gferi_RS06250	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
Gferi_RS06260	COG3829	transcription factor binding
Gferi_RS06305	COG2871	sodium ion transport
Gferi_RS06320	COG1410	methionine synthase
Gferi_RS06320	COG0646	methionine synthase
Gferi_RS06340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Gferi_RS06355	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Gferi_RS06360	COG3404	Formiminotransferase-cyclodeaminase
Gferi_RS06365	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Gferi_RS06375	COG1151	hydroxylamine reductase activity
Gferi_RS06395	COG0393	Putative heavy-metal-binding
Gferi_RS06430	COG1846	Transcriptional regulator
Gferi_RS06480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Gferi_RS06500	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
Gferi_RS06510	COG1131	(ABC) transporter
Gferi_RS06515	COG1725	Transcriptional regulator
Gferi_RS06520	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Gferi_RS06535	COG3829	transcription factor binding
Gferi_RS06540	COG0686	Belongs to the AlaDH PNT family
Gferi_RS06545	COG1757	Na H antiporter
Gferi_RS06555	COG0159	tryptophan synthase activity
Gferi_RS06560	COG0133	tryptophan synthase activity
Gferi_RS06570	COG0134	indole-3-glycerol-phosphate synthase activity
Gferi_RS06575	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Gferi_RS06580	COG0512	Glutamine amidotransferase of anthranilate synthase
Gferi_RS06580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Gferi_RS06590	COG0488	(ABC) transporter
Gferi_RS06595	COG2508	Transcriptional regulator
Gferi_RS06600	COG3842	ATPase activity
Gferi_RS06630	COG0577	efflux transmembrane transporter activity
Gferi_RS06630	COG1136	(ABC) transporter
Gferi_RS06640	COG2814	Major facilitator Superfamily
Gferi_RS06645	COG1309	transcriptional regulator
Gferi_RS06650	COG0789	Transcriptional regulator
Gferi_RS06660	COG2207	Transcriptional regulator
Gferi_RS06665	COG0772	Belongs to the SEDS family
Gferi_RS06670	COG1695	Transcriptional regulator
Gferi_RS06675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Gferi_RS06685	COG2721	sulfolactate sulfo-lyase activity
Gferi_RS06695	COG1414	Transcriptional regulator
Gferi_RS06705	COG2081	HI0933 family
Gferi_RS06725	COG1737	Transcriptional regulator
Gferi_RS06740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Gferi_RS06770	COG1132	(ABC) transporter
Gferi_RS06780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Gferi_RS06815	COG0840	transmembrane signaling receptor activity
Gferi_RS06820	COG2197	response regulator
Gferi_RS06835	COG3459	Glycosyltransferase 36 associated
Gferi_RS06840	COG3459	Glycosyltransferase 36 associated
Gferi_RS06845	COG0395	ABC-type sugar transport system, permease component
Gferi_RS06870	COG0860	N-Acetylmuramoyl-L-alanine amidase
Gferi_RS06880	COG1442	glycosyl transferase family 8
Gferi_RS06900	COG0463	Glycosyl transferase, family 2
Gferi_RS06900	COG0457	Tetratricopeptide repeat
Gferi_RS06910	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Gferi_RS06915	COG1091	dTDP-4-dehydrorhamnose reductase activity
Gferi_RS06930	COG0438	transferase activity, transferring glycosyl groups
Gferi_RS06930	COG1216	Glycosyl transferase, family 2
Gferi_RS06945	COG2089	acid synthase
Gferi_RS06955	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
Gferi_RS06960	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Gferi_RS06965	COG1088	dTDP-glucose 4,6-dehydratase activity
Gferi_RS06970	COG1086	Polysaccharide biosynthesis protein
Gferi_RS07065	COG0346	lactoylglutathione lyase activity
Gferi_RS07080	COG0584	glycerophosphoryl diester phosphodiesterase
Gferi_RS07095	COG1136	(ABC) transporter
Gferi_RS07105	COG1304	FMN binding
Gferi_RS07115	COG4106	trans-aconitate 2-methyltransferase activity
Gferi_RS07120	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Gferi_RS07125	COG0577	efflux transmembrane transporter activity
Gferi_RS07130	COG1136	(ABC) transporter
Gferi_RS07135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Gferi_RS07145	COG5002	protein histidine kinase activity
Gferi_RS07150	COG0745	RESPONSE REGULATOR receiver
Gferi_RS07160	COG0436	Aminotransferase
Gferi_RS07165	COG3314	Sporulation integral membrane protein YlbJ
Gferi_RS07170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Gferi_RS07175	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Gferi_RS07200	COG2851	Citrate transporter
Gferi_RS07205	COG3290	protein histidine kinase activity
Gferi_RS07205	COG3829	transcription factor binding
Gferi_RS07210	COG1307	EDD domain protein, DegV family
Gferi_RS07220	COG0745	RESPONSE REGULATOR receiver
Gferi_RS07225	COG5002	protein histidine kinase activity
Gferi_RS07230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Gferi_RS07250	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Gferi_RS07270	COG3655	Transcriptional regulator
Gferi_RS07285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Gferi_RS07295	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Gferi_RS07300	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Gferi_RS07305	COG0583	DNA-binding transcription factor activity
Gferi_RS07330	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Gferi_RS07335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Gferi_RS07340	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Gferi_RS07345	COG1309	transcriptional regulator
Gferi_RS07355	COG2391	methyltransferase activity
Gferi_RS07360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Gferi_RS07360	COG0425	Belongs to the sulfur carrier protein TusA family
Gferi_RS07365	COG2391	methyltransferase activity
Gferi_RS07380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Gferi_RS07385	COG0463	Glycosyl transferase, family 2
Gferi_RS07425	COG1376	ErfK ybiS ycfS ynhG family protein
Gferi_RS07440	COG1011	Hydrolase
Gferi_RS07445	COG0309	Hydrogenase expression formation protein (HypE)
Gferi_RS07450	COG0409	Hydrogenase expression formation protein
Gferi_RS07460	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Gferi_RS07490	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Gferi_RS07510	COG1349	DNA-binding transcription factor activity
Gferi_RS07515	COG3842	ATPase activity
Gferi_RS07520	COG1178	ABC-type Fe3 transport system permease component
Gferi_RS07525	COG1176	ABC-type spermidine putrescine transport system, permease component I
Gferi_RS07540	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
Gferi_RS07550	COG1376	ErfK ybiS ycfS ynhG family protein
Gferi_RS07555	COG4608	Belongs to the ABC transporter superfamily
Gferi_RS07565	COG0747	negative chemotaxis
Gferi_RS07570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Gferi_RS07575	COG0601	transmembrane transport
Gferi_RS07580	COG1073	alpha beta
Gferi_RS07580	COG2226	methyltransferase
Gferi_RS07600	COG0640	Transcriptional regulator
Gferi_RS07605	COG2217	Heavy metal translocating P-type atpase
Gferi_RS07610	COG2217	Heavy metal translocating P-type atpase
Gferi_RS07630	COG2226	methyltransferase
Gferi_RS07635	COG0745	RESPONSE REGULATOR receiver
Gferi_RS07640	COG2205	protein histidine kinase activity
Gferi_RS07650	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
Gferi_RS07660	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Gferi_RS07665	COG1376	ErfK ybiS ycfS ynhG family protein
Gferi_RS07680	COG3842	ATPase activity
Gferi_RS07690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Gferi_RS07710	COG0860	N-Acetylmuramoyl-L-alanine amidase
Gferi_RS07715	COG5002	protein histidine kinase activity
Gferi_RS07725	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Gferi_RS07730	COG0583	DNA-binding transcription factor activity
Gferi_RS07755	COG5002	protein histidine kinase activity
Gferi_RS07785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Gferi_RS07795	COG3314	Sporulation integral membrane protein YlbJ
Gferi_RS07805	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Gferi_RS07820	COG5012	cobalamin binding
Gferi_RS07825	COG5598	trimethylamine methyltransferase
Gferi_RS07830	COG3829	transcription factor binding
Gferi_RS07840	COG1120	ATPase activity
Gferi_RS07845	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Gferi_RS07850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Gferi_RS07865	COG1312	Catalyzes the dehydration of D-mannonate
Gferi_RS07885	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Gferi_RS07895	COG0789	Transcriptional regulator
Gferi_RS07915	COG2814	Major facilitator Superfamily
Gferi_RS07925	COG1408	metallophosphoesterase
Gferi_RS07930	COG3173	Aminoglycoside phosphotransferase
Gferi_RS07935	COG3173	Aminoglycoside phosphotransferase
Gferi_RS07960	COG5002	protein histidine kinase activity
Gferi_RS07965	COG0745	RESPONSE REGULATOR receiver
Gferi_RS07995	COG4257	antibiotic catabolic process
Gferi_RS08010	COG1309	transcriptional regulator
Gferi_RS08015	COG0604	alcohol dehydrogenase
Gferi_RS08015	COG1028	Short-chain dehydrogenase reductase Sdr
Gferi_RS08015	COG3321	synthase
Gferi_RS08020	COG0778	Nitroreductase
Gferi_RS08025	COG3848	Pyruvate phosphate dikinase
Gferi_RS08025	COG0574	Belongs to the PEP-utilizing enzyme family
Gferi_RS08050	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
Gferi_RS08055	COG4770	biotin carboxylase activity
Gferi_RS08065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Gferi_RS08090	COG0789	Transcriptional regulator
Gferi_RS08100	COG2201	protein-glutamate methylesterase activity
Gferi_RS08105	COG2972	Histidine kinase
Gferi_RS08110	COG0534	Mate efflux family protein
Gferi_RS08120	COG0444	Belongs to the ABC transporter superfamily
Gferi_RS08125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Gferi_RS08130	COG0601	transmembrane transport
Gferi_RS08150	COG1012	belongs to the aldehyde dehydrogenase family
Gferi_RS08175	COG1129	ABC transporter
Gferi_RS08230	COG0736	holo-[acyl-carrier-protein] synthase activity
Gferi_RS08235	COG0280	phosphate acetyltransferase
Gferi_RS08250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Gferi_RS08255	COG2207	Transcriptional regulator
Gferi_RS08290	COG2205	protein histidine kinase activity
Gferi_RS08295	COG0577	efflux transmembrane transporter activity
Gferi_RS08295	COG1136	(ABC) transporter
Gferi_RS08320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Gferi_RS08325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Gferi_RS08330	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Gferi_RS08335	COG1454	alcohol dehydrogenase
Gferi_RS08340	COG3395	kinase activity
Gferi_RS08350	COG0346	lactoylglutathione lyase activity
Gferi_RS08355	COG0667	Aldo Keto reductase
Gferi_RS08360	COG1172	Belongs to the binding-protein-dependent transport system permease family
Gferi_RS08365	COG1129	ABC transporter
Gferi_RS08395	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
Gferi_RS08400	COG3180	Ammonia monooxygenase
Gferi_RS08405	COG0583	DNA-binding transcription factor activity
Gferi_RS08425	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Gferi_RS08430	COG3051	citrate lyase alpha subunit
Gferi_RS08440	COG3052	prosthetic group binding
Gferi_RS08455	COG1288	antiporter activity
Gferi_RS08465	COG0066	3-isopropylmalate dehydratase activity
Gferi_RS08470	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Gferi_RS08485	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Gferi_RS08525	COG1695	Transcriptional regulator
Gferi_RS08555	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Gferi_RS08560	COG1612	heme a metabolic process
Gferi_RS08560	COG0109	protoheme IX farnesyltransferase activity
Gferi_RS08565	COG0163	prenyltransferase activity
Gferi_RS08580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Gferi_RS08585	COG0826	peptidase U32
Gferi_RS08590	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Gferi_RS08595	COG0814	amino acid
Gferi_RS08605	COG0697	spore germination
Gferi_RS08610	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Gferi_RS08615	COG1328	CTP reductase activity
Gferi_RS08650	COG2770	Histidine kinase
Gferi_RS08650	COG3437	response regulator, receiver
Gferi_RS08680	COG0800	Aldolase
Gferi_RS08685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Gferi_RS08690	COG0800	Aldolase
Gferi_RS08705	COG5001	Diguanylate cyclase
Gferi_RS08745	COG4166	transmembrane transport
Gferi_RS08750	COG1309	transcriptional regulator
Gferi_RS08755	COG0574	Belongs to the PEP-utilizing enzyme family
Gferi_RS08755	COG3848	Pyruvate phosphate dikinase
Gferi_RS08775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Gferi_RS08795	COG0395	ABC-type sugar transport system, permease component
Gferi_RS08800	COG4209	transmembrane transport
Gferi_RS08815	COG2186	Transcriptional regulator
Gferi_RS08840	COG5002	protein histidine kinase activity
Gferi_RS08845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Gferi_RS08855	COG1472	Belongs to the glycosyl hydrolase 3 family
Gferi_RS08865	COG2340	Cysteine-rich secretory protein family
Gferi_RS08870	COG1278	Cold shock
Gferi_RS08880	COG2094	Belongs to the DNA glycosylase MPG family
Gferi_RS08900	COG3973	AAA domain
Gferi_RS08910	COG0494	nUDIX hydrolase
Gferi_RS08920	COG0646	methionine synthase
Gferi_RS08920	COG1410	methionine synthase
Gferi_RS08930	COG4717	serine-type aminopeptidase activity
Gferi_RS08935	COG0420	3'-5' exonuclease activity
Gferi_RS08940	COG2996	Protein conserved in bacteria
Gferi_RS08945	COG1428	Deoxynucleoside kinase
Gferi_RS08955	COG0534	Mate efflux family protein
Gferi_RS08965	COG1863	multisubunit Na H antiporter MnhE subunit
Gferi_RS08975	COG1320	monovalent cation:proton antiporter activity
Gferi_RS08995	COG1006	Multisubunit Na H antiporter MnhC subunit
Gferi_RS09000	COG2111	Na H antiporter
Gferi_RS09000	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Gferi_RS09015	COG0070	glutamate synthase
Gferi_RS09015	COG0067	glutamate synthase
Gferi_RS09015	COG0069	glutamate synthase activity
Gferi_RS09040	COG4187	Peptidase family M20/M25/M40
Gferi_RS09045	COG1053	succinate dehydrogenase
Gferi_RS09045	COG3976	FMN-binding domain protein
Gferi_RS09050	COG1397	ADP-ribosylglycohydrolase
Gferi_RS09055	COG3091	SprT-like family
Gferi_RS09065	COG3290	protein histidine kinase activity
Gferi_RS09065	COG3829	transcription factor binding
Gferi_RS09095	COG0674	pyruvate-flavodoxin oxidoreductase activity
Gferi_RS09095	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Gferi_RS09100	COG1013	pyruvate-flavodoxin oxidoreductase activity
Gferi_RS09130	COG0840	transmembrane signaling receptor activity
Gferi_RS09135	COG2340	Cysteine-rich secretory protein family
Gferi_RS09150	COG0733	neurotransmitter:sodium symporter activity
Gferi_RS09155	COG5002	protein histidine kinase activity
Gferi_RS09160	COG0745	RESPONSE REGULATOR receiver
Gferi_RS09165	COG1136	(ABC) transporter
Gferi_RS09175	COG0577	efflux transmembrane transporter activity
Gferi_RS09175	COG1136	(ABC) transporter
Gferi_RS09200	COG1129	ABC transporter
Gferi_RS09200	COG0842	Transport permease protein
Gferi_RS09205	COG1131	(ABC) transporter
Gferi_RS09215	COG1309	transcriptional regulator
Gferi_RS09220	COG3858	chitin binding
Gferi_RS09230	COG2059	Chromate
Gferi_RS09235	COG2309	aminopeptidase activity
Gferi_RS09250	COG1943	Transposase
Gferi_RS09255	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Gferi_RS09260	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Gferi_RS09265	COG1067	ATP-dependent peptidase activity
Gferi_RS09265	COG0470	DNA polymerase III
Gferi_RS09270	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Gferi_RS09275	COG0740	serine-type endopeptidase activity
Gferi_RS09280	COG0544	peptidyl-prolyl cis-trans isomerase activity
Gferi_RS09285	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
Gferi_RS09295	COG1079	Belongs to the binding-protein-dependent transport system permease family
Gferi_RS09300	COG4603	Belongs to the binding-protein-dependent transport system permease family
Gferi_RS09305	COG3845	ABC transporter
Gferi_RS09310	COG1744	ABC transporter substrate-binding protein PnrA-like
Gferi_RS09320	COG2201	protein-glutamate methylesterase activity
Gferi_RS09330	COG1366	Belongs to the anti-sigma-factor antagonist family
Gferi_RS09340	COG0643	Histidine kinase
Gferi_RS09340	COG2198	Histidine kinase
Gferi_RS09345	COG0835	chemotaxis
Gferi_RS09350	COG0840	transmembrane signaling receptor activity
Gferi_RS09370	COG3706	GGDEF domain
Gferi_RS09375	COG0681	Belongs to the peptidase S26 family
Gferi_RS09390	COG0210	DNA helicase
Gferi_RS09400	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Gferi_RS09400	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Gferi_RS09415	COG2340	Cysteine-rich secretory protein family
Gferi_RS09460	COG0622	Phosphoesterase
Gferi_RS09470	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Gferi_RS09480	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
Gferi_RS09500	COG3069	C4-dicarboxylate transmembrane transporter activity
Gferi_RS09505	COG4166	transmembrane transport
Gferi_RS09510	COG4608	Belongs to the ABC transporter superfamily
Gferi_RS09515	COG0444	Belongs to the ABC transporter superfamily
Gferi_RS09520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Gferi_RS09525	COG0601	transmembrane transport
Gferi_RS09530	COG0154	amidase activity
Gferi_RS09545	COG0210	DNA helicase
Gferi_RS09565	COG1882	Formate acetyltransferase
Gferi_RS09575	COG1882	Formate acetyltransferase
Gferi_RS09580	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Gferi_RS09590	COG0183	Belongs to the thiolase family
Gferi_RS09595	COG1250	3-hydroxyacyl-CoA dehydrogenase
Gferi_RS09600	COG0840	transmembrane signaling receptor activity
Gferi_RS09605	COG2843	Capsule synthesis protein
Gferi_RS09610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Gferi_RS09625	COG2851	Citrate transporter
Gferi_RS09630	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Gferi_RS09635	COG2086	electron transfer activity
Gferi_RS09640	COG1960	acyl-CoA dehydrogenase activity
Gferi_RS09655	COG1882	Formate acetyltransferase
Gferi_RS09680	COG0840	transmembrane signaling receptor activity
Gferi_RS09685	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Gferi_RS09705	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Gferi_RS09710	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Gferi_RS09725	COG1250	3-hydroxyacyl-CoA dehydrogenase
Gferi_RS09730	COG3246	L-lysine catabolic process to acetate
Gferi_RS09760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Gferi_RS09770	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Gferi_RS09780	COG2188	Transcriptional regulator
Gferi_RS09785	COG1028	Short-chain dehydrogenase reductase Sdr
Gferi_RS09795	COG0726	polysaccharide deacetylase
Gferi_RS09805	COG1120	ATPase activity
Gferi_RS09840	COG2832	Protein of unknown function (DUF454)
Gferi_RS09845	COG4988	ABC transporter
Gferi_RS09850	COG1132	(ABC) transporter
Gferi_RS09860	COG0167	dihydroorotate dehydrogenase activity
Gferi_RS09865	COG0543	2 iron, 2 sulfur cluster binding
Gferi_RS09870	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Gferi_RS09875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Gferi_RS09885	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Gferi_RS09890	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Gferi_RS09895	COG1414	Transcriptional regulator
Gferi_RS09900	COG4496	protein, YerC YecD
Gferi_RS09905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Gferi_RS09910	COG2011	ABC-type metal ion transport system permease component
Gferi_RS09925	COG4948	Mandelate Racemase Muconate Lactonizing
Gferi_RS09935	COG4166	transmembrane transport
Gferi_RS09945	COG1473	amidohydrolase
Gferi_RS09960	COG1473	amidohydrolase
Gferi_RS09965	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Gferi_RS09970	COG3279	Response regulator of the LytR AlgR family
Gferi_RS09985	COG1522	sequence-specific DNA binding
Gferi_RS09990	COG0151	Belongs to the GarS family
Gferi_RS09995	COG0138	bifunctional purine biosynthesis protein purh
Gferi_RS10000	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Gferi_RS10005	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Gferi_RS10010	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Gferi_RS10015	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Gferi_RS10020	COG2252	PERMEase
Gferi_RS10025	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Gferi_RS10030	COG0583	DNA-binding transcription factor activity
Gferi_RS10035	COG0840	transmembrane signaling receptor activity
Gferi_RS10040	COG0352	thiamine-phosphate diphosphorylase activity
Gferi_RS10045	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
Gferi_RS10050	COG0351	phosphomethylpyrimidine kinase
Gferi_RS10060	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Gferi_RS10065	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Gferi_RS10080	COG3459	Glycosyltransferase 36 associated
Gferi_RS10085	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Gferi_RS10090	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Gferi_RS10095	COG0840	transmembrane signaling receptor activity
Gferi_RS10110	COG5275	peptidyl-tyrosine sulfation
Gferi_RS10110	COG0252	asparaginase activity
Gferi_RS10115	COG0252	asparaginase activity
Gferi_RS10115	COG5275	peptidyl-tyrosine sulfation
Gferi_RS10120	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
Gferi_RS10125	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
Gferi_RS10135	COG5275	peptidyl-tyrosine sulfation
Gferi_RS10135	COG0252	asparaginase activity
Gferi_RS10140	COG4656	Part of a membrane complex involved in electron transport
Gferi_RS10145	COG3290	protein histidine kinase activity
Gferi_RS10145	COG3829	transcription factor binding
Gferi_RS10155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Gferi_RS10160	COG2207	Transcriptional regulator
Gferi_RS10160	COG3708	Transcriptional regulator
Gferi_RS10165	COG0516	GMP reductase activity
Gferi_RS10165	COG0517	IMP dehydrogenase activity
Gferi_RS10180	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Gferi_RS10185	COG3246	L-lysine catabolic process to acetate
Gferi_RS10190	COG0183	Belongs to the thiolase family
Gferi_RS10195	COG3829	transcription factor binding
Gferi_RS10195	COG3290	protein histidine kinase activity
Gferi_RS10205	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Gferi_RS10205	COG0519	Catalyzes the synthesis of GMP from XMP
Gferi_RS10210	COG0516	GMP reductase activity
Gferi_RS10210	COG0517	IMP dehydrogenase activity
Gferi_RS10275	COG0459	protein refolding
Gferi_RS10280	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Gferi_RS10285	COG2068	MobA-Related Protein
Gferi_RS10460	COG2755	lipolytic protein G-D-S-L family
Gferi_RS10465	COG1191	sigma factor activity
Gferi_RS10475	COG1811	Na channel or pump
Gferi_RS10485	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Gferi_RS10495	COG1361	Conserved repeat domain
Gferi_RS10495	COG3266	domain, Protein
Gferi_RS10495	COG2911	Protein conserved in bacteria
Gferi_RS10510	COG2221	Nitrite and sulphite reductase 4Fe-4S
Gferi_RS10520	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Gferi_RS10525	COG2086	electron transfer activity
Gferi_RS10530	COG1960	acyl-CoA dehydrogenase activity
Gferi_RS10535	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Gferi_RS10540	COG0488	(ABC) transporter
Gferi_RS10545	COG0493	'glutamate synthase
Gferi_RS10560	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Gferi_RS10590	COG1595	DNA-templated transcription, initiation
Gferi_RS10595	COG0577	efflux transmembrane transporter activity
Gferi_RS10600	COG1136	(ABC) transporter
Gferi_RS10610	COG0456	acetyltransferase
Gferi_RS10615	COG1214	PFAM Peptidase M22, glycoprotease
Gferi_RS10620	COG0802	atpase or kinase
Gferi_RS10630	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
Gferi_RS10640	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Gferi_RS10650	COG0546	phosphoglycolate phosphatase activity
Gferi_RS10655	COG2183	response to ionizing radiation
Gferi_RS10660	COG0840	transmembrane signaling receptor activity
Gferi_RS10665	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Gferi_RS10670	COG0653	protein targeting
Gferi_RS10685	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Gferi_RS10710	COG1516	flagellar protein fliS
Gferi_RS10715	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Gferi_RS10740	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Gferi_RS10745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Gferi_RS10745	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Gferi_RS10755	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Gferi_RS10760	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Gferi_RS10765	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
Gferi_RS10775	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Gferi_RS10780	COG1256	bacterial-type flagellum assembly
Gferi_RS10780	COG4786	Flagellar basal body rod
Gferi_RS10800	COG1040	competence protein
Gferi_RS10805	COG3706	GGDEF domain
Gferi_RS10810	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Gferi_RS10840	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Gferi_RS10850	COG0658	competence protein
Gferi_RS10850	COG2333	competence protein COMEC
Gferi_RS10895	COG2234	aminopeptidase activity
Gferi_RS10910	COG0697	spore germination
Gferi_RS10925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Gferi_RS10930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Gferi_RS10935	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Gferi_RS10940	COG3951	Flagellar rod assembly protein muramidase FlgJ
Gferi_RS10940	COG1705	Flagellar rod assembly protein muramidase FlgJ
Gferi_RS10955	COG1077	Cell shape determining protein MreB Mrl
Gferi_RS10960	COG1609	Transcriptional regulator
Gferi_RS10970	COG2385	sporulation resulting in formation of a cellular spore
Gferi_RS10975	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Gferi_RS11010	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Gferi_RS11015	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Gferi_RS11020	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Gferi_RS11025	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Gferi_RS11030	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Gferi_RS11065	COG3246	L-lysine catabolic process to acetate
Gferi_RS11070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Gferi_RS11080	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Gferi_RS11085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Gferi_RS11090	COG2131	deaminase
Gferi_RS11095	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Gferi_RS11100	COG0698	ribose 5-phosphate isomerase
Gferi_RS11105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Gferi_RS11110	COG0009	L-threonylcarbamoyladenylate synthase
Gferi_RS11115	COG0428	transporter
Gferi_RS11120	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Gferi_RS11130	COG2890	protein-(glutamine-N5) methyltransferase activity
Gferi_RS11135	COG3872	metal-dependent enzyme
Gferi_RS11140	COG2031	fatty acid transporter
Gferi_RS11150	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Gferi_RS11155	COG0183	Belongs to the thiolase family
Gferi_RS11160	COG3290	protein histidine kinase activity
Gferi_RS11160	COG3829	transcription factor binding
Gferi_RS11165	COG1435	thymidine kinase activity
Gferi_RS11170	COG0254	rRNA binding
Gferi_RS11175	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Gferi_RS11180	COG1494	fructose-1,6-bisphosphatase
Gferi_RS11185	COG1494	fructose-1,6-bisphosphatase
Gferi_RS11195	COG3246	L-lysine catabolic process to acetate
Gferi_RS11200	COG1607	acyl-coa hydrolase
Gferi_RS11210	COG1394	ATPase activity, coupled to movement of substances
Gferi_RS11240	COG1269	ATP hydrolysis coupled proton transport
Gferi_RS11265	COG1309	transcriptional regulator
Gferi_RS11290	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Gferi_RS11320	COG0438	transferase activity, transferring glycosyl groups
Gferi_RS11340	COG1086	Polysaccharide biosynthesis protein
Gferi_RS11360	COG1846	Transcriptional regulator
Gferi_RS11360	COG0456	acetyltransferase
Gferi_RS11365	COG0363	glucosamine-6-phosphate deaminase activity
Gferi_RS11370	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Gferi_RS11370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Gferi_RS11375	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Gferi_RS11380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Gferi_RS11390	COG3206	protein involved in exopolysaccharide biosynthesis
Gferi_RS11390	COG0489	protein tyrosine kinase activity
Gferi_RS11395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Gferi_RS11400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Gferi_RS11410	COG1846	Transcriptional regulator
Gferi_RS11435	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Gferi_RS11475	COG3409	Peptidoglycan-binding domain 1 protein
Gferi_RS11475	COG0793	Belongs to the peptidase S41A family
Gferi_RS11480	COG2373	Large extracellular alpha-helical protein
Gferi_RS11500	COG2373	Large extracellular alpha-helical protein
Gferi_RS11505	COG1376	ErfK ybiS ycfS ynhG family protein
Gferi_RS11510	COG5012	cobalamin binding
Gferi_RS11515	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Gferi_RS11520	COG1193	negative regulation of DNA recombination
Gferi_RS11535	COG0604	alcohol dehydrogenase
Gferi_RS11540	COG3829	transcription factor binding
Gferi_RS11545	COG0018	arginyl-trna synthetase
Gferi_RS11555	COG1181	Belongs to the D-alanine--D-alanine ligase family
Gferi_RS11560	COG2959	enzyme of heme biosynthesis
Gferi_RS11580	COG0814	amino acid
Gferi_RS11585	COG0697	spore germination
Gferi_RS11595	COG1802	Transcriptional regulator
Gferi_RS11600	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Gferi_RS11610	COG1361	Conserved repeat domain
Gferi_RS11625	COG2197	response regulator
Gferi_RS11630	COG4585	Histidine kinase
Gferi_RS11640	COG1388	LysM domain
Gferi_RS11640	COG3942	CHAP domain
Gferi_RS11660	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Gferi_RS11665	COG2235	arginine
Gferi_RS11675	COG1757	Na H antiporter
Gferi_RS11680	COG0577	efflux transmembrane transporter activity
Gferi_RS11680	COG1136	(ABC) transporter
Gferi_RS11690	COG1136	(ABC) transporter
Gferi_RS11695	COG4466	Protein conserved in bacteria
Gferi_RS11700	COG2385	sporulation resulting in formation of a cellular spore
Gferi_RS11710	COG1028	Short-chain dehydrogenase reductase Sdr
Gferi_RS11715	COG3829	transcription factor binding
Gferi_RS11715	COG3290	protein histidine kinase activity
Gferi_RS11720	COG0183	Belongs to the thiolase family
Gferi_RS11730	COG2610	gluconate transmembrane transporter activity
Gferi_RS11740	COG2030	dehydratase
Gferi_RS11750	COG0735	belongs to the Fur family
Gferi_RS11780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Gferi_RS11785	COG1121	(ABC) transporter
Gferi_RS11790	COG0803	Belongs to the bacterial solute-binding protein 9 family
Gferi_RS11790	COG3443	Belongs to the bacterial solute-binding protein 9 family
Gferi_RS11810	COG3693	PFAM glycoside hydrolase, family 10
Gferi_RS11835	COG1151	hydroxylamine reductase activity
Gferi_RS11845	COG1522	sequence-specific DNA binding
Gferi_RS11865	COG0531	amino acid
Gferi_RS11875	COG0697	spore germination
Gferi_RS11880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Gferi_RS11885	COG5002	protein histidine kinase activity
Gferi_RS11890	COG0745	RESPONSE REGULATOR receiver
Gferi_RS11915	COG2116	formate transmembrane transporter activity
Gferi_RS11930	COG0328	RNA-DNA hybrid ribonuclease activity
Gferi_RS11950	COG1136	(ABC) transporter
Gferi_RS11955	COG0577	efflux transmembrane transporter activity
Gferi_RS11990	COG0697	spore germination
Gferi_RS11995	COG1982	Orn Lys Arg decarboxylase major
Gferi_RS12000	COG1408	metallophosphoesterase
Gferi_RS12005	COG1051	belongs to the nudix hydrolase family
Gferi_RS12015	COG2195	Cleaves the N-terminal amino acid of tripeptides
Gferi_RS12020	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
Gferi_RS12035	COG1937	Protein conserved in bacteria
Gferi_RS12045	COG2210	Belongs to the sulfur carrier protein TusA family
Gferi_RS12055	COG0446	pyridine nucleotide-disulphide oxidoreductase
Gferi_RS12060	COG1442	glycosyl transferase family 8
Gferi_RS12075	COG0347	Belongs to the P(II) protein family
Gferi_RS12080	COG0004	ammonium transporteR
Gferi_RS12100	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Gferi_RS12110	COG3584	3D domain protein
Gferi_RS12115	COG0084	hydrolase, TatD family'
Gferi_RS12120	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Gferi_RS12120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Gferi_RS12135	COG0700	Nucleoside recognition
Gferi_RS12140	COG2715	membrane protein required for spore maturation
Gferi_RS12155	COG0617	tRNA 3'-terminal CCA addition
Gferi_RS12160	COG2002	toxin-antitoxin pair type II binding
Gferi_RS12170	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Gferi_RS12175	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Gferi_RS12180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Gferi_RS12185	COG2221	Nitrite and sulphite reductase 4Fe-4S
Gferi_RS12190	COG1774	PSP1 C-terminal conserved region
Gferi_RS12195	COG0470	DNA polymerase III
Gferi_RS12200	COG3870	Protein conserved in bacteria
Gferi_RS12205	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Gferi_RS12210	COG1982	Orn Lys Arg decarboxylase major
Gferi_RS12250	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Gferi_RS12260	COG0697	spore germination
Gferi_RS12265	COG0814	amino acid
Gferi_RS12275	COG1013	pyruvate-flavodoxin oxidoreductase activity
Gferi_RS12280	COG0674	pyruvate-flavodoxin oxidoreductase activity
Gferi_RS12290	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Gferi_RS12315	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Gferi_RS12320	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Gferi_RS12325	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Gferi_RS12345	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Gferi_RS12355	COG1595	DNA-templated transcription, initiation
Gferi_RS12360	COG2323	membrane
Gferi_RS12370	COG1924	4 iron, 4 sulfur cluster binding
Gferi_RS12375	COG0723	plastoquinol--plastocyanin reductase activity
Gferi_RS12375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Gferi_RS12385	COG2378	regulation of single-species biofilm formation
Gferi_RS12400	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Gferi_RS12400	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Gferi_RS12405	COG4821	SIS domain
Gferi_RS12410	COG3716	PTS system mannose fructose sorbose family IID component
Gferi_RS12415	COG3715	PTS system
Gferi_RS12420	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Gferi_RS12420	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Gferi_RS12425	COG2188	Transcriptional regulator
Gferi_RS12430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Gferi_RS12435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Gferi_RS12450	COG1115	amino acid carrier protein
Gferi_RS12455	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Gferi_RS12475	COG0326	Molecular chaperone. Has ATPase activity
Gferi_RS12480	COG0534	Mate efflux family protein
Gferi_RS12505	COG0745	RESPONSE REGULATOR receiver
Gferi_RS12515	COG2226	methyltransferase
Gferi_RS12550	COG1136	(ABC) transporter
Gferi_RS12555	COG0514	ATP-dependent DNA helicase (RecQ)
Gferi_RS12565	COG2949	membrane
Gferi_RS12585	COG0590	tRNA wobble adenosine to inosine editing
Gferi_RS12590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Gferi_RS12595	COG0363	glucosamine-6-phosphate deaminase activity
Gferi_RS12600	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
Gferi_RS12605	COG3457	Alanine racemase
Gferi_RS12610	COG0626	cystathionine gamma-synthase activity
Gferi_RS12615	COG1735	metal-dependent hydrolase with the TIM-barrel fold
Gferi_RS12640	COG2188	Transcriptional regulator
Gferi_RS12650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Gferi_RS12670	COG2340	Cysteine-rich secretory protein family
Gferi_RS12675	COG0840	transmembrane signaling receptor activity
Gferi_RS12685	COG0456	acetyltransferase
Gferi_RS12690	COG2205	protein histidine kinase activity
Gferi_RS12740	COG1686	Belongs to the peptidase S11 family
Gferi_RS12750	COG1482	cell wall glycoprotein biosynthetic process
Gferi_RS12755	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Gferi_RS12760	COG0006	proline dipeptidase activity
Gferi_RS12765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Gferi_RS12770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Gferi_RS12790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Gferi_RS12795	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Gferi_RS12800	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Gferi_RS12805	COG0505	Belongs to the CarA family
Gferi_RS12810	COG0505	Belongs to the CarA family
Gferi_RS12815	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Gferi_RS12820	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Gferi_RS12825	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Gferi_RS12830	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Gferi_RS12925	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Gferi_RS12945	COG1994	Peptidase M50
Gferi_RS12950	COG1615	UPF0182 protein
Gferi_RS12960	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Gferi_RS12965	COG1827	regulation of RNA biosynthetic process
Gferi_RS12970	COG0189	ligase activity
Gferi_RS12970	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Gferi_RS12980	COG0840	transmembrane signaling receptor activity
Gferi_RS12990	COG0444	Belongs to the ABC transporter superfamily
Gferi_RS12995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Gferi_RS13000	COG0601	transmembrane transport
Gferi_RS13005	COG1802	Transcriptional regulator
Gferi_RS13010	COG0137	argininosuccinate synthase activity
Gferi_RS13015	COG0165	Argininosuccinate lyase
Gferi_RS13035	COG0446	pyridine nucleotide-disulphide oxidoreductase
Gferi_RS13045	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Gferi_RS13060	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
Gferi_RS13075	COG1785	Belongs to the alkaline phosphatase family
Gferi_RS13095	COG2376	Dihydroxyacetone kinase
Gferi_RS13100	COG3829	transcription factor binding
Gferi_RS13100	COG3290	protein histidine kinase activity
Gferi_RS13150	COG1573	uracil-dna glycosylase
Gferi_RS13155	COG1573	uracil-dna glycosylase
Gferi_RS13195	COG0180	Tryptophanyl-tRNA synthetase
Gferi_RS13210	COG1191	sigma factor activity
Gferi_RS13220	COG1366	Belongs to the anti-sigma-factor antagonist family
Gferi_RS13230	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Gferi_RS13235	COG0187	DNA topoisomerase II activity
Gferi_RS13245	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Gferi_RS13255	COG0592	DNA-directed DNA polymerase activity
Gferi_RS13260	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Gferi_RS13265	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Gferi_RS13270	COG0594	ribonuclease P activity
Gferi_RS13275	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Gferi_RS13280	COG0706	membrane insertase activity
Gferi_RS13285	COG1847	R3H domain protein
Gferi_RS13290	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Gferi_RS13295	COG0445	tRNA wobble uridine modification
Gferi_RS13300	COG0357	Ribosomal RNA small subunit methyltransferase G
Gferi_RS13315	COG1192	Involved in chromosome partitioning
Gferi_RS13320	COG1475	DNA binding
Gferi_RS13325	COG0384	phenazine biosynthesis protein PhzF
Gferi_RS13345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Gferi_RS13365	COG1597	lipid kinase activity
Gferi_RS13385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Gferi_RS13390	COG0644	oxidoreductase
Gferi_RS13400	COG3457	Alanine racemase
Gferi_RS13405	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Gferi_RS13410	COG0287	Prephenate dehydrogenase
Gferi_RS13415	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Gferi_RS13425	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Gferi_RS13430	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Gferi_RS13435	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Gferi_RS13450	COG0710	3-dehydroquinate dehydratase activity
Gferi_RS13455	COG0028	Belongs to the TPP enzyme family
Gferi_RS13475	COG1414	Transcriptional regulator
Gferi_RS13480	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Gferi_RS13485	COG0697	spore germination
Gferi_RS13490	COG0840	transmembrane signaling receptor activity
Gferi_RS13495	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Gferi_RS13500	COG1012	belongs to the aldehyde dehydrogenase family
Gferi_RS13510	COG3852	Histidine kinase
Gferi_RS13515	COG2204	response regulator
Gferi_RS13520	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Gferi_RS13525	COG1914	H( )-stimulated, divalent metal cation uptake system
Gferi_RS13530	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Gferi_RS13535	COG1984	allophanate hydrolase subunit 2
Gferi_RS13540	COG0840	transmembrane signaling receptor activity
Gferi_RS13555	COG0640	Transcriptional regulator
Gferi_RS13560	COG5658	integral membrane protein
Gferi_RS13570	COG3949	Membrane
Gferi_RS13600	COG0668	transmembrane transport
Gferi_RS13610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Gferi_RS13615	COG3852	Histidine kinase
Gferi_RS13620	COG2204	response regulator
Gferi_RS13625	COG2358	TRAP transporter, solute receptor (TAXI family
Gferi_RS13645	COG0360	Binds together with S18 to 16S ribosomal RNA
Gferi_RS13655	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Gferi_RS13675	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
Gferi_RS13680	COG0359	binds to the 23S rRNA
Gferi_RS13685	COG1067	ATP-dependent peptidase activity
Gferi_RS13685	COG0470	DNA polymerase III
Gferi_RS13690	COG0305	Participates in initiation and elongation during chromosome replication
Gferi_RS13700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Gferi_RS13715	COG2323	membrane
Gferi_RS13720	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Gferi_RS13735	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Gferi_RS13750	COG0739	heme binding
Gferi_RS13755	COG1404	Belongs to the peptidase S8 family
Gferi_RS13765	COG0745	RESPONSE REGULATOR receiver
Gferi_RS13770	COG5002	protein histidine kinase activity
Gferi_RS13795	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Gferi_RS13800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Gferi_RS13810	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Gferi_RS13845	COG2361	Protein of unknown function DUF86
Gferi_RS13870	COG4974	Belongs to the 'phage' integrase family
Gferi_RS13875	COG0517	IMP dehydrogenase activity
Gferi_RS13905	COG1181	Belongs to the D-alanine--D-alanine ligase family
Gferi_RS13910	COG4555	ABC transporter
Gferi_RS13945	COG1088	dTDP-glucose 4,6-dehydratase activity
Gferi_RS13950	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Gferi_RS13955	COG1484	DNA-dependent DNA replication
Gferi_RS13985	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Gferi_RS13990	COG4166	transmembrane transport
Gferi_RS14020	COG1876	peptidase activity
Gferi_RS14025	COG0745	RESPONSE REGULATOR receiver
Gferi_RS14030	COG5002	protein histidine kinase activity
Gferi_RS14050	COG2267	carboxylic ester hydrolase activity
Gferi_RS14055	COG1309	transcriptional regulator
Gferi_RS14075	COG1131	(ABC) transporter
Gferi_RS14090	COG1309	transcriptional regulator
Gferi_RS14095	COG1131	(ABC) transporter
Gferi_RS14100	COG3559	Exporter of polyketide antibiotics
Gferi_RS14125	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Gferi_RS14135	COG0583	DNA-binding transcription factor activity
Gferi_RS14170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Gferi_RS14175	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Gferi_RS14185	COG4753	response regulator
Gferi_RS14185	COG2207	Transcriptional regulator
Gferi_RS14190	COG2972	Histidine kinase
Gferi_RS14200	COG1129	ABC transporter
Gferi_RS14205	COG1172	Belongs to the binding-protein-dependent transport system permease family
Gferi_RS14220	COG1940	carbohydrate kinase activity
Gferi_RS14225	COG1940	carbohydrate kinase activity
Gferi_RS14235	COG1595	DNA-templated transcription, initiation
Gferi_RS14250	COG0326	Molecular chaperone. Has ATPase activity
Gferi_RS14260	COG1842	Phage shock protein A
Gferi_RS14265	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Gferi_RS14270	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
Gferi_RS14275	COG4260	virion core protein, lumpy skin disease virus
Gferi_RS14295	COG0530	calcium, potassium:sodium antiporter activity
Gferi_RS14335	COG3695	enzyme binding
Gferi_RS14340	COG0778	Nitroreductase
Gferi_RS14340	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
Gferi_RS14355	COG2239	Acts as a magnesium transporter
Gferi_RS14360	COG0384	phenazine biosynthesis protein PhzF
Gferi_RS14370	COG3180	Ammonia monooxygenase
Gferi_RS14385	COG2358	TRAP transporter, solute receptor (TAXI family
Gferi_RS14395	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Gferi_RS14405	COG0129	dihydroxy-acid dehydratase activity
Gferi_RS14410	COG0385	Bile acid
Gferi_RS14415	COG2207	Transcriptional regulator
Gferi_RS14435	COG0583	DNA-binding transcription factor activity
Gferi_RS14450	COG1396	sequence-specific DNA binding
Gferi_RS14460	COG0745	RESPONSE REGULATOR receiver
Gferi_RS14465	COG5002	protein histidine kinase activity
Gferi_RS14470	COG1595	DNA-templated transcription, initiation
Gferi_RS14485	COG2205	protein histidine kinase activity
Gferi_RS14485	COG2770	Histidine kinase
Gferi_RS14490	COG0745	RESPONSE REGULATOR receiver
Gferi_RS14505	COG3299	homolog of phage Mu protein gp47
Gferi_RS14590	COG3299	homolog of phage Mu protein gp47
Gferi_RS14620	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Gferi_RS14625	COG2119	membrane
Gferi_RS14635	COG0534	Mate efflux family protein
Gferi_RS14645	COG1802	Transcriptional regulator
Gferi_RS14655	COG1028	Short-chain dehydrogenase reductase Sdr
Gferi_RS14670	COG2986	histidine ammonia-lyase
Gferi_RS14685	COG1802	Transcriptional regulator
Gferi_RS14690	COG1312	Catalyzes the dehydration of D-mannonate
Gferi_RS14695	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Gferi_RS14705	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Gferi_RS14710	COG1063	alcohol dehydrogenase
Gferi_RS14715	COG1028	Short-chain dehydrogenase reductase Sdr
Gferi_RS14735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Gferi_RS14745	COG1131	(ABC) transporter
Gferi_RS14750	COG1725	Transcriptional regulator
Gferi_RS14765	COG5002	protein histidine kinase activity
Gferi_RS14770	COG0745	RESPONSE REGULATOR receiver
Gferi_RS14790	COG1119	ATPase activity
Gferi_RS14795	COG0527	aspartate kinase activity
Gferi_RS14815	COG0697	spore germination
Gferi_RS14820	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Gferi_RS14835	COG0708	Exodeoxyribonuclease III
Gferi_RS14845	COG1454	alcohol dehydrogenase
Gferi_RS14865	COG0653	protein targeting
Gferi_RS14875	COG3973	AAA domain
Gferi_RS14905	COG2972	Histidine kinase
Gferi_RS14910	COG2207	Transcriptional regulator
Gferi_RS14910	COG4753	response regulator
Gferi_RS14915	COG4213	ABC transporter substrate-binding protein
Gferi_RS14925	COG1129	ABC transporter
Gferi_RS14930	COG4211	Belongs to the binding-protein-dependent transport system permease family
Gferi_RS14935	COG2357	RelA SpoT domain protein
Gferi_RS14945	COG3829	transcription factor binding
Gferi_RS14950	COG1757	Na H antiporter
Gferi_RS14985	COG2226	methyltransferase
Gferi_RS14995	COG1032	radical SAM domain protein
Gferi_RS15005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Gferi_RS15010	COG0840	transmembrane signaling receptor activity
Gferi_RS15015	COG0488	(ABC) transporter
Gferi_RS15025	COG1472	Belongs to the glycosyl hydrolase 3 family
Gferi_RS15030	COG3069	C4-dicarboxylate transmembrane transporter activity
Gferi_RS15040	COG5002	protein histidine kinase activity
Gferi_RS15050	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Gferi_RS15060	COG3830	Belongs to the UPF0237 family
Gferi_RS15065	COG0488	(ABC) transporter
Gferi_RS15070	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Gferi_RS15085	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
Gferi_RS15100	COG1193	negative regulation of DNA recombination
Gferi_RS15105	COG1802	Transcriptional regulator
Gferi_RS15110	COG0488	(ABC) transporter
Gferi_RS15210	COG1132	(ABC) transporter
Gferi_RS15215	COG1132	(ABC) transporter
Gferi_RS15225	COG0346	lactoylglutathione lyase activity
Gferi_RS15230	COG1757	Na H antiporter
Gferi_RS15235	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Gferi_RS15245	COG0739	heme binding
Gferi_RS15245	COG1196	nuclear chromosome segregation
Gferi_RS15245	COG0741	lytic transglycosylase activity
Gferi_RS15250	COG5001	Diguanylate cyclase
Gferi_RS15250	COG3300	MHYT domain
Gferi_RS15260	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Gferi_RS15295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Gferi_RS15300	COG1164	Oligoendopeptidase f
Gferi_RS15305	COG5002	protein histidine kinase activity
Gferi_RS15310	COG0745	RESPONSE REGULATOR receiver
Gferi_RS15325	COG0322	excinuclease ABC activity
Gferi_RS15335	COG1968	undecaprenyl-diphosphatase activity
Gferi_RS15340	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Gferi_RS15345	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Gferi_RS15370	COG2210	Belongs to the sulfur carrier protein TusA family
Gferi_RS15375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Gferi_RS15380	COG1132	(ABC) transporter
Gferi_RS15395	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Gferi_RS15395	COG1918	ferrous iron import across plasma membrane
Gferi_RS15425	COG5598	trimethylamine methyltransferase
Gferi_RS15430	COG5598	trimethylamine methyltransferase
Gferi_RS15440	COG5012	cobalamin binding
Gferi_RS15445	COG3829	transcription factor binding
Gferi_RS15475	COG0840	transmembrane signaling receptor activity
Gferi_RS15485	COG3875	lactate racemase activity
Gferi_RS15495	COG1012	belongs to the aldehyde dehydrogenase family
Gferi_RS15500	COG1846	Transcriptional regulator
Gferi_RS15505	COG0534	Mate efflux family protein
Gferi_RS15520	COG2188	Transcriptional regulator
Gferi_RS15525	COG1263	PTS System
Gferi_RS15525	COG2190	(PTS) system
Gferi_RS15525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Gferi_RS15530	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Gferi_RS15540	COG2190	(PTS) system
Gferi_RS15555	COG1956	GAF domain-containing protein
Gferi_RS15560	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Gferi_RS15565	COG0835	chemotaxis
Gferi_RS15570	COG0840	transmembrane signaling receptor activity
Gferi_RS15580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Gferi_RS15595	COG4166	transmembrane transport
Gferi_RS15645	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
Gferi_RS15655	COG1063	alcohol dehydrogenase
Gferi_RS15665	COG2199	diguanylate cyclase activity
Gferi_RS15665	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Gferi_RS15670	COG0071	Belongs to the small heat shock protein (HSP20) family
Gferi_RS15695	COG5564	TIM-barrel signal transduction protein
Gferi_RS15705	COG0477	Major facilitator Superfamily
Gferi_RS15710	COG0116	Belongs to the methyltransferase superfamily
Gferi_RS15725	COG0028	Belongs to the TPP enzyme family
Gferi_RS15730	COG0440	acetolactate synthase activity
Gferi_RS15735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Gferi_RS15740	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Gferi_RS15745	COG0066	3-isopropylmalate dehydratase activity
Gferi_RS15750	COG0473	3-isopropylmalate dehydrogenase activity
Gferi_RS15755	COG1376	ErfK ybiS ycfS ynhG family protein
Gferi_RS15760	COG1335	isochorismatase
Gferi_RS15770	COG1151	hydroxylamine reductase activity
Gferi_RS15785	COG3842	ATPase activity
Gferi_RS15790	COG1176	ABC-type spermidine putrescine transport system, permease component I
Gferi_RS15795	COG1177	transmembrane transport
Gferi_RS15815	COG2323	membrane
Gferi_RS15860	COG4303	Ethanolamine ammonia lyase large subunit
Gferi_RS15875	COG4816	utilization protein
Gferi_RS15885	COG1012	belongs to the aldehyde dehydrogenase family
Gferi_RS15885	COG1454	alcohol dehydrogenase
Gferi_RS15900	COG4869	propanediol catabolic process
Gferi_RS15910	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
Gferi_RS15915	COG4656	Part of a membrane complex involved in electron transport
Gferi_RS15935	COG3192	ethanolamine utilization protein
Gferi_RS15945	COG3279	Response regulator of the LytR AlgR family
Gferi_RS15950	COG3290	protein histidine kinase activity
Gferi_RS15995	COG1968	undecaprenyl-diphosphatase activity
Gferi_RS16030	COG1620	l-lactate permease
Gferi_RS16035	COG2086	electron transfer activity
Gferi_RS16040	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Gferi_RS16045	COG0277	FAD linked oxidase domain protein
Gferi_RS16065	COG1473	amidohydrolase
Gferi_RS16075	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Gferi_RS16080	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
Gferi_RS16090	COG0446	pyridine nucleotide-disulphide oxidoreductase
Gferi_RS16105	COG5002	protein histidine kinase activity
Gferi_RS16115	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Gferi_RS16120	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Gferi_RS16135	COG0786	glutamate:sodium symporter activity
Gferi_RS16140	COG2204	response regulator
Gferi_RS16145	COG3852	Histidine kinase
Gferi_RS16155	COG0179	Fumarylacetoacetate (FAA) hydrolase
Gferi_RS16185	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Gferi_RS16195	COG3845	ABC transporter
Gferi_RS16200	COG4603	Belongs to the binding-protein-dependent transport system permease family
Gferi_RS16205	COG1079	Belongs to the binding-protein-dependent transport system permease family
Gferi_RS16210	COG1971	Probably functions as a manganese efflux pump
Gferi_RS16215	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Gferi_RS16230	COG3829	transcription factor binding
Gferi_RS16235	COG0733	neurotransmitter:sodium symporter activity
Gferi_RS16285	COG3052	prosthetic group binding
Gferi_RS16290	COG2301	Belongs to the HpcH HpaI aldolase family
Gferi_RS16295	COG3051	citrate lyase alpha subunit
Gferi_RS16300	COG0511	ligase activity, forming carbon-carbon bonds
Gferi_RS16300	COG5016	pyruvate
Gferi_RS16315	COG1733	regulation of RNA biosynthetic process
Gferi_RS16320	COG5012	cobalamin binding
Gferi_RS16325	COG2188	Transcriptional regulator
Gferi_RS16340	COG5012	cobalamin binding
Gferi_RS16365	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Gferi_RS16375	COG5012	cobalamin binding
Gferi_RS16385	COG2211	Major facilitator Superfamily
Gferi_RS16390	COG5012	cobalamin binding
Gferi_RS16400	COG5012	cobalamin binding
Gferi_RS16405	COG2188	Transcriptional regulator
Gferi_RS16420	COG1606	tRNA processing
Gferi_RS16425	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Gferi_RS16430	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
Gferi_RS16440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Gferi_RS16455	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
Gferi_RS16515	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Gferi_RS16525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Gferi_RS16530	COG1217	gtp-binding protein TYPA
Gferi_RS16550	COG3875	lactate racemase activity
Gferi_RS16555	COG1464	Belongs to the NlpA lipoprotein family
Gferi_RS16575	COG2268	Band 7 protein
Gferi_RS16580	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Gferi_RS16595	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Gferi_RS16600	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Gferi_RS16605	COG1647	Serine aminopeptidase, S33
Gferi_RS16615	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Gferi_RS16660	COG1757	Na H antiporter
Gferi_RS16665	COG0527	aspartate kinase activity
Gferi_RS16680	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Gferi_RS16690	COG1024	Enoyl-CoA hydratase
Gferi_RS16695	COG1250	3-hydroxyacyl-CoA dehydrogenase
Gferi_RS16710	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Gferi_RS16715	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Gferi_RS16720	COG2088	sporulation resulting in formation of a cellular spore
Gferi_RS16725	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Gferi_RS16735	COG0840	transmembrane signaling receptor activity
Gferi_RS16740	COG0193	aminoacyl-tRNA hydrolase activity
Gferi_RS16745	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Gferi_RS16750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Gferi_RS16755	COG2002	toxin-antitoxin pair type II binding
Gferi_RS16760	COG2244	polysaccharide biosynthetic process
Gferi_RS16765	COG3956	TIGRFAM MazG family protein
Gferi_RS16775	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Gferi_RS16780	COG2385	sporulation resulting in formation of a cellular spore
Gferi_RS16800	COG1098	S1 RNA binding domain
Gferi_RS16805	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Gferi_RS16805	COG0248	Ppx GppA phosphatase
Gferi_RS16820	COG5002	protein histidine kinase activity
Gferi_RS16825	COG2208	phosphoserine phosphatase activity
Gferi_RS16830	COG2304	oxidoreductase activity
Gferi_RS16835	COG0515	serine threonine protein kinase
Gferi_RS16840	COG0037	tRNA processing
Gferi_RS16845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Gferi_RS16870	COG0427	acetyl-CoA hydrolase
Gferi_RS16875	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Gferi_RS16875	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Gferi_RS16880	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Gferi_RS16880	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Gferi_RS16890	COG0346	lactoylglutathione lyase activity
Gferi_RS16895	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Gferi_RS16905	COG4770	biotin carboxylase activity
Gferi_RS16910	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
Gferi_RS16915	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Gferi_RS16915	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Gferi_RS16925	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Gferi_RS16930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Gferi_RS16940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Gferi_RS16945	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Gferi_RS16980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Gferi_RS16985	COG1597	lipid kinase activity
Gferi_RS16990	COG0860	N-Acetylmuramoyl-L-alanine amidase
Gferi_RS17005	COG1794	racemase activity, acting on amino acids and derivatives
Gferi_RS17015	COG0436	Aminotransferase
Gferi_RS17030	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Gferi_RS17035	COG0495	leucyl-tRNA aminoacylation
Gferi_RS17040	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Gferi_RS17040	COG1199	ATP-dependent helicase activity
Gferi_RS17045	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Gferi_RS17055	COG1528	Iron-storage protein
Gferi_RS17060	COG0693	protein deglycase activity
Gferi_RS17075	COG4251	negative regulation of phosphorylation
Gferi_RS17080	COG0784	Response regulator, receiver
Gferi_RS17090	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Gferi_RS17110	COG3880	PFAM UvrB UvrC protein
Gferi_RS17115	COG3869	Catalyzes the specific phosphorylation of arginine residues in
Gferi_RS17120	COG0542	response to heat
Gferi_RS17130	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Gferi_RS17135	COG0083	homoserine kinase activity
Gferi_RS17140	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Gferi_RS17160	COG1329	Transcriptional regulator
Gferi_RS17165	COG4956	integral membrane protein (PIN domain superfamily)
Gferi_RS17170	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Gferi_RS17175	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
Gferi_RS17195	COG3732	PTS system glucitol sorbitol-specific
Gferi_RS17210	COG0561	phosphatase activity
Gferi_RS17215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Gferi_RS17220	COG0022	dehydrogenase e1 component
Gferi_RS17225	COG0508	dehydrogenase complex catalyzes the overall conversion of
Gferi_RS17230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Gferi_RS17235	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Gferi_RS17245	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Gferi_RS17250	COG0442	prolyl-tRNA aminoacylation
Gferi_RS17255	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Gferi_RS17260	COG1045	serine acetyltransferase
Gferi_RS17265	COG0215	cysteine-tRNA ligase activity
Gferi_RS17285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Gferi_RS17290	COG3688	RNA-binding protein containing a PIN domain
Gferi_RS17305	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Gferi_RS17320	COG0250	Participates in transcription elongation, termination and antitermination
Gferi_RS17330	COG0081	regulation of translation
Gferi_RS17335	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Gferi_RS17355	COG0085	RNA polymerase activity
Gferi_RS17360	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Gferi_RS17365	COG1358	cellular component organization or biogenesis
Gferi_RS17370	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Gferi_RS17375	COG0049	tRNA binding
Gferi_RS17380	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Gferi_RS17385	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Gferi_RS17390	COG0051	transcription antitermination factor activity, RNA binding
Gferi_RS17395	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Gferi_RS17400	COG0088	Forms part of the polypeptide exit tunnel
Gferi_RS17405	COG0089	rRNA binding
Gferi_RS17410	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Gferi_RS17420	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Gferi_RS17425	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Gferi_RS17430	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Gferi_RS17435	COG0255	Belongs to the universal ribosomal protein uL29 family
Gferi_RS17440	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Gferi_RS17445	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Gferi_RS17450	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Gferi_RS17455	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Gferi_RS17460	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Gferi_RS17465	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Gferi_RS17470	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Gferi_RS17475	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Gferi_RS17480	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Gferi_RS17490	COG0200	Binds to the 23S rRNA
Gferi_RS17495	COG0201	protein transport
Gferi_RS17500	COG0563	adenylate kinase activity
Gferi_RS17505	COG0024	Methionine aminopeptidase
Gferi_RS17525	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Gferi_RS17530	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Gferi_RS17535	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Gferi_RS17540	COG0202	RNA polymerase activity
Gferi_RS17545	COG0203	ribosomal protein L17
Gferi_RS17550	COG1122	ATPase activity
Gferi_RS17560	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Gferi_RS17565	COG0101	tRNA pseudouridine synthase activity
Gferi_RS17570	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Gferi_RS17575	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Gferi_RS17585	COG0628	permease
Gferi_RS17595	COG5012	cobalamin binding
Gferi_RS17610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Gferi_RS17610	COG2207	Transcriptional regulator
Gferi_RS17625	COG0860	N-Acetylmuramoyl-L-alanine amidase
Gferi_RS17630	COG3885	ferrous iron binding
Gferi_RS17630	COG2078	PFAM AMMECR1 domain protein
Gferi_RS17640	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Gferi_RS17650	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Gferi_RS17655	COG0737	Belongs to the 5'-nucleotidase family
Gferi_RS17660	COG0095	Lipoate-protein ligase
Gferi_RS17665	COG5002	protein histidine kinase activity
Gferi_RS17670	COG3314	Sporulation integral membrane protein YlbJ
Gferi_RS17680	COG2720	vancomycin resistance protein
Gferi_RS17700	COG1574	metal-dependent hydrolase with the TIM-barrel fold
Gferi_RS17720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Gferi_RS17730	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
Gferi_RS17730	COG2508	Transcriptional regulator
Gferi_RS17740	COG5012	cobalamin binding
Gferi_RS17775	COG0587	DNA-directed DNA polymerase activity
Gferi_RS17790	COG3976	FMN-binding domain protein
Gferi_RS17790	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
Gferi_RS17800	COG4974	Belongs to the 'phage' integrase family
Gferi_RS17805	COG0517	IMP dehydrogenase activity
Gferi_RS17860	COG2119	membrane
Gferi_RS17875	COG0800	Aldolase
Gferi_RS17880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Gferi_RS17890	COG1917	Cupin 2, conserved barrel domain protein
Gferi_RS17895	COG2972	Histidine kinase
Gferi_RS17900	COG3279	Response regulator of the LytR AlgR family
Gferi_RS17905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Gferi_RS17920	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Gferi_RS17945	COG1546	Belongs to the CinA family
Gferi_RS17945	COG1058	Belongs to the CinA family
Gferi_RS17950	COG3608	succinylglutamate desuccinylase aspartoacylase
Gferi_RS17950	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Gferi_RS17955	COG1414	Transcriptional regulator
Gferi_RS17970	COG3971	2-oxopent-4-enoate hydratase activity
Gferi_RS17975	COG4569	acetaldehyde dehydrogenase (acetylating) activity
Gferi_RS17980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Gferi_RS18000	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Gferi_RS18010	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Gferi_RS18015	COG1606	tRNA processing
Gferi_RS18020	COG1691	(AIR) carboxylase
Gferi_RS18030	COG3829	transcription factor binding
Gferi_RS18030	COG3290	protein histidine kinase activity
Gferi_RS18035	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
Gferi_RS18040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Gferi_RS18055	COG2376	Dihydroxyacetone kinase
Gferi_RS18060	COG1461	Dihydroxyacetone kinase
Gferi_RS18065	COG0149	triose-phosphate isomerase activity
Gferi_RS18070	COG0698	ribose 5-phosphate isomerase
Gferi_RS18075	COG1704	LemA family
Gferi_RS18085	COG0733	neurotransmitter:sodium symporter activity
Gferi_RS18090	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Gferi_RS18105	COG4974	Belongs to the 'phage' integrase family
Gferi_RS18110	COG0517	IMP dehydrogenase activity
Gferi_RS18170	COG0427	acetyl-CoA hydrolase
Gferi_RS18175	COG1250	3-hydroxyacyl-CoA dehydrogenase
Gferi_RS18175	COG1024	Enoyl-CoA hydratase
Gferi_RS18180	COG0183	Belongs to the thiolase family
Gferi_RS18195	COG3959	Transketolase, thiamine diphosphate binding domain
Gferi_RS18200	COG3958	Transketolase
Gferi_RS18210	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Gferi_RS18215	COG0066	3-isopropylmalate dehydratase activity
Gferi_RS18220	COG0583	DNA-binding transcription factor activity
Gferi_RS18240	COG2851	Citrate transporter
Gferi_RS18260	COG0492	ferredoxin-NADP+ reductase activity
Gferi_RS18265	COG0583	DNA-binding transcription factor activity
Gferi_RS18270	COG0840	transmembrane signaling receptor activity
Gferi_RS18325	COG4869	propanediol catabolic process
Gferi_RS18330	COG4820	ethanolamine utilization protein (EutJ)
Gferi_RS18340	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
Gferi_RS18350	COG1012	belongs to the aldehyde dehydrogenase family
Gferi_RS18355	COG4656	Part of a membrane complex involved in electron transport
Gferi_RS18370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Gferi_RS18375	COG1929	Belongs to the glycerate kinase type-1 family
Gferi_RS18385	COG2197	response regulator
Gferi_RS18435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Gferi_RS18435	COG5322	oxidoreductase activity
Gferi_RS18450	COG1924	4 iron, 4 sulfur cluster binding
Gferi_RS18460	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
Gferi_RS18465	COG0540	Belongs to the ATCase OTCase family
Gferi_RS18470	COG0284	orotidine-5'-phosphate decarboxylase activity
Gferi_RS18475	COG0543	2 iron, 2 sulfur cluster binding
Gferi_RS18480	COG0167	dihydroorotate dehydrogenase activity
Gferi_RS18490	COG2323	membrane
Gferi_RS18495	COG1846	Transcriptional regulator
Gferi_RS18530	COG0436	Aminotransferase
Gferi_RS18545	COG0601	transmembrane transport
Gferi_RS18550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Gferi_RS18565	COG2508	Transcriptional regulator
Gferi_RS18715	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
Gferi_RS18720	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
Gferi_RS18725	COG0347	Belongs to the P(II) protein family
Gferi_RS18730	COG0347	Belongs to the P(II) protein family
Gferi_RS18755	COG1433	Dinitrogenase iron-molybdenum cofactor
Gferi_RS18755	COG0535	radical SAM domain protein
Gferi_RS18760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Gferi_RS18765	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Gferi_RS18795	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Gferi_RS18800	COG4856	YbbR-like protein
Gferi_RS18805	COG3290	protein histidine kinase activity
Gferi_RS18805	COG3829	transcription factor binding
Gferi_RS18810	COG3426	butyrate kinase activity
Gferi_RS18815	COG0280	phosphate acetyltransferase
Gferi_RS18820	COG3426	butyrate kinase activity
Gferi_RS18850	COG1695	Transcriptional regulator
Gferi_RS18870	COG1966	Carbon starvation protein
Gferi_RS18880	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Gferi_RS18885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Gferi_RS18890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Gferi_RS18905	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Gferi_RS18940	COG0653	protein targeting
Gferi_RS19015	COG1595	DNA-templated transcription, initiation
Gferi_RS19030	COG0697	spore germination
Gferi_RS19035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Gferi_RS19040	COG4145	pantothenate transmembrane transporter activity
Gferi_RS19045	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
Gferi_RS19065	COG2378	regulation of single-species biofilm formation
Gferi_RS19100	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Gferi_RS19100	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Gferi_RS19105	COG3715	PTS system
Gferi_RS19110	COG3716	PTS system mannose fructose sorbose family IID component
Gferi_RS19135	COG2188	Transcriptional regulator
Gferi_RS19145	COG0242	peptide deformylase activity
Gferi_RS19185	COG2226	methyltransferase
Gferi_RS19195	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Gferi_RS19205	COG3608	succinylglutamate desuccinylase aspartoacylase
Gferi_RS19205	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Gferi_RS19210	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Gferi_RS19225	COG3608	succinylglutamate desuccinylase aspartoacylase
Gferi_RS19225	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Gferi_RS19230	COG0725	ABC transporter, periplasmic molybdate-binding protein
Gferi_RS19235	COG4149	molybdate abc transporter
Gferi_RS19240	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Gferi_RS19245	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
Gferi_RS19250	COG1653	transport
Gferi_RS19255	COG1175	transmembrane transport
Gferi_RS19260	COG0395	ABC-type sugar transport system, permease component
Gferi_RS19265	COG3842	ATPase activity
Gferi_RS19275	COG1396	sequence-specific DNA binding
Gferi_RS19280	COG1882	Formate acetyltransferase
Gferi_RS19285	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Gferi_RS19300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Gferi_RS19305	COG4974	Belongs to the 'phage' integrase family
Gferi_RS19315	COG1473	amidohydrolase
Gferi_RS19320	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
Gferi_RS19325	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
Gferi_RS19335	COG5012	cobalamin binding
Gferi_RS19350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Gferi_RS19355	COG0789	Transcriptional regulator
Gferi_RS19375	COG0534	Mate efflux family protein
Gferi_RS19390	COG0456	acetyltransferase
Gferi_RS19395	COG1396	sequence-specific DNA binding
Gferi_RS19405	COG3706	GGDEF domain
Gferi_RS19410	COG0583	DNA-binding transcription factor activity
Gferi_RS19415	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Gferi_RS19425	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Gferi_RS19425	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Gferi_RS19450	COG0640	Transcriptional regulator
Gferi_RS19460	COG4555	ABC transporter
Gferi_RS19475	COG0840	transmembrane signaling receptor activity
Gferi_RS19480	COG0028	Belongs to the TPP enzyme family
Gferi_RS19510	COG0577	efflux transmembrane transporter activity
Gferi_RS19510	COG1136	(ABC) transporter
Gferi_RS19515	COG5002	protein histidine kinase activity
Gferi_RS19530	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Gferi_RS19535	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Gferi_RS19540	COG0438	transferase activity, transferring glycosyl groups
Gferi_RS19550	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Gferi_RS19555	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Gferi_RS19570	COG4191	Histidine kinase
Gferi_RS19575	COG2204	response regulator
Gferi_RS19585	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Gferi_RS19610	COG1396	sequence-specific DNA binding
Gferi_RS19620	COG2199	diguanylate cyclase activity
Gferi_RS19635	COG1252	NADH dehydrogenase
Gferi_RS19655	COG1408	metallophosphoesterase
Gferi_RS19685	COG2315	Protein conserved in bacteria
Gferi_RS19695	COG1192	Involved in chromosome partitioning
Gferi_RS19705	COG3711	transcriptional antiterminator
Gferi_RS19710	COG2213	PTS system mannitol-specific
Gferi_RS19710	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Gferi_RS19720	COG1063	alcohol dehydrogenase
Gferi_RS19725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Gferi_RS19730	COG1830	Aldolase
Gferi_RS19740	COG1070	Carbohydrate kinase
Gferi_RS19765	COG1879	ABC-type sugar transport system periplasmic component
Gferi_RS19770	COG0205	6-phosphofructokinase activity
Gferi_RS19775	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Gferi_RS19785	COG4443	Transcriptional Coactivator p15 (PC4)
Gferi_RS19790	COG2188	Transcriptional regulator
Gferi_RS19795	COG5012	cobalamin binding
Gferi_RS19820	COG1129	ABC transporter
Gferi_RS19825	COG4211	Belongs to the binding-protein-dependent transport system permease family
Gferi_RS19830	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Gferi_RS19835	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Gferi_RS19840	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
Gferi_RS19855	COG1609	Transcriptional regulator
Gferi_RS19860	COG0697	spore germination
Gferi_RS19900	COG1388	LysM domain
Gferi_RS19900	COG3858	chitin binding
Gferi_RS19930	COG5012	cobalamin binding
Gferi_RS19935	COG1962	PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit
Gferi_RS19940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Gferi_RS19945	COG5598	trimethylamine methyltransferase
Gferi_RS19950	COG5012	cobalamin binding
Gferi_RS19955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Gferi_RS19965	COG0813	purine-nucleoside phosphorylase activity
Gferi_RS19975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Gferi_RS19985	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Gferi_RS19995	COG2205	protein histidine kinase activity
Gferi_RS20015	COG2226	methyltransferase
Gferi_RS20025	COG1124	(ABC) transporter
Gferi_RS20030	COG0444	Belongs to the ABC transporter superfamily
Gferi_RS20035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Gferi_RS20040	COG0601	transmembrane transport
Gferi_RS20045	COG0747	negative chemotaxis
Gferi_RS20050	COG0747	negative chemotaxis
Gferi_RS20055	COG0601	transmembrane transport
Gferi_RS20060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Gferi_RS20065	COG0444	Belongs to the ABC transporter superfamily
Gferi_RS20070	COG4608	Belongs to the ABC transporter superfamily
Gferi_RS20075	COG1073	alpha beta
Gferi_RS20075	COG2226	methyltransferase
Gferi_RS20080	COG1132	(ABC) transporter
Gferi_RS20085	COG1132	(ABC) transporter
Gferi_RS20090	COG3693	PFAM glycoside hydrolase, family 10
Gferi_RS20095	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
Gferi_RS20105	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
Gferi_RS20115	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Gferi_RS20120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Gferi_RS20125	COG0805	protein transport
Gferi_RS20130	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Gferi_RS20185	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Gferi_RS20190	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Gferi_RS20195	COG1321	iron dependent repressor
Gferi_RS20205	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Gferi_RS20210	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Gferi_RS20210	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Gferi_RS20230	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Gferi_RS20240	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Gferi_RS20255	COG2032	superoxide dismutase activity
Gferi_RS20260	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Gferi_RS20295	COG1653	transport
Gferi_RS20300	COG1175	transmembrane transport
Gferi_RS20305	COG0395	ABC-type sugar transport system, permease component
Gferi_RS20325	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
Gferi_RS20330	COG1074	ATP-dependent DNA helicase activity
Gferi_RS20340	COG0419	ATPase involved in DNA repair
Gferi_RS20345	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Gferi_RS20350	COG0726	polysaccharide deacetylase
Gferi_RS20355	COG0688	phosphatidylethanolamine metabolic process
Gferi_RS20360	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Gferi_RS20370	COG1943	Transposase
Gferi_RS20380	COG2226	methyltransferase
Gferi_RS20395	COG2239	Acts as a magnesium transporter
Gferi_RS20400	COG2239	Acts as a magnesium transporter
Gferi_RS20405	COG0840	transmembrane signaling receptor activity
Gferi_RS20410	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Gferi_RS20415	COG0573	inorganic phosphate transmembrane transporter activity
Gferi_RS20420	COG0581	inorganic phosphate transmembrane transporter activity
Gferi_RS20435	COG5002	protein histidine kinase activity
Gferi_RS20450	COG0517	IMP dehydrogenase activity
Gferi_RS20450	COG1125	glycine betaine transport
Gferi_RS20460	COG0736	holo-[acyl-carrier-protein] synthase activity
Gferi_RS20465	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Gferi_RS20465	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Gferi_RS20470	COG0517	IMP dehydrogenase activity
Gferi_RS20470	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Gferi_RS20470	COG0617	tRNA 3'-terminal CCA addition
Gferi_RS20480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Gferi_RS20490	COG2337	Toxic component of a toxin-antitoxin (TA) module
Gferi_RS20520	COG0438	transferase activity, transferring glycosyl groups
Gferi_RS20525	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Gferi_RS20545	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Gferi_RS20550	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Gferi_RS20555	COG3959	Transketolase, thiamine diphosphate binding domain
Gferi_RS20560	COG3958	Transketolase
Gferi_RS20580	COG1067	ATP-dependent peptidase activity
Gferi_RS20585	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Gferi_RS20590	COG2884	Cell division ATP-binding protein ftsE
Gferi_RS20595	COG2177	Part of the ABC transporter FtsEX involved in
Gferi_RS20600	COG0739	heme binding
Gferi_RS20610	COG1194	a g-specific adenine glycosylase
Gferi_RS20615	COG0534	Mate efflux family protein
Gferi_RS20620	COG1592	Rubrerythrin
Gferi_RS20625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Gferi_RS20630	COG0793	Belongs to the peptidase S41A family
Gferi_RS20635	COG3103	Sh3 type 3 domain protein
Gferi_RS20635	COG0366	Alpha amylase catalytic
Gferi_RS20640	COG0058	SHG alpha-glucan phosphorylase activity
Gferi_RS20645	COG0297	glycogen (starch) synthase activity
Gferi_RS20650	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Gferi_RS20655	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Gferi_RS20660	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Gferi_RS20670	COG3279	Response regulator of the LytR AlgR family
Gferi_RS20675	COG5002	protein histidine kinase activity
Gferi_RS20675	COG0784	Response regulator, receiver
Gferi_RS20675	COG2205	protein histidine kinase activity
Gferi_RS20680	COG5002	protein histidine kinase activity
Gferi_RS20680	COG5001	Diguanylate cyclase
Gferi_RS20680	COG3447	MASE1 domain protein
Gferi_RS20685	COG0556	nucleotide-excision repair
Gferi_RS20690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Gferi_RS20730	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Gferi_RS20735	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Gferi_RS20740	COG0322	excinuclease ABC activity
Gferi_RS20745	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
Gferi_RS20755	COG0521	Mo-molybdopterin cofactor biosynthetic process
Gferi_RS20795	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Gferi_RS20815	COG0303	'Molybdopterin
Gferi_RS20820	COG0303	'Molybdopterin
Gferi_RS20825	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Gferi_RS20830	COG0315	cyclic pyranopterin monophosphate synthase activity
Gferi_RS20840	COG0659	secondary active sulfate transmembrane transporter activity
Gferi_RS20845	COG2116	formate transmembrane transporter activity
Gferi_RS20880	COG0058	SHG alpha-glucan phosphorylase activity
Gferi_RS20890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Gferi_RS20895	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Gferi_RS20900	COG1660	Displays ATPase and GTPase activities
Gferi_RS20905	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Gferi_RS20910	COG0840	transmembrane signaling receptor activity
Gferi_RS20915	COG3033	Beta-eliminating lyase
Gferi_RS20930	COG1481	regulation of sporulation
Gferi_RS20945	COG4109	DRTGG domain
Gferi_RS20960	COG0205	6-phosphofructokinase activity
Gferi_RS20975	COG3030	protein affecting phage T7 exclusion by the F plasmid
Gferi_RS20985	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Gferi_RS21000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Gferi_RS21030	COG2205	protein histidine kinase activity
Gferi_RS21035	COG0745	RESPONSE REGULATOR receiver
Gferi_RS21070	COG3012	SEC-C Motif Domain Protein
Gferi_RS21140	COG0590	tRNA wobble adenosine to inosine editing
Gferi_RS21150	COG0037	tRNA processing
Gferi_RS21175	COG3279	Response regulator of the LytR AlgR family
Gferi_RS21180	COG3279	Response regulator of the LytR AlgR family
Gferi_RS21195	COG2199	diguanylate cyclase activity
Gferi_RS21200	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Gferi_RS21225	COG1335	isochorismatase
Gferi_RS21275	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Gferi_RS21290	COG0384	phenazine biosynthesis protein PhzF
Gferi_RS21300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Gferi_RS21385	COG1024	Enoyl-CoA hydratase
Gferi_RS21390	COG1309	transcriptional regulator
Gferi_RS21410	COG1129	ABC transporter
Gferi_RS21455	COG1012	belongs to the aldehyde dehydrogenase family
Gferi_RS21475	COG0574	Belongs to the PEP-utilizing enzyme family
Gferi_RS21475	COG3848	Pyruvate phosphate dikinase
Gferi_RS21480	COG1028	Short-chain dehydrogenase reductase Sdr
Gferi_RS21490	COG0745	RESPONSE REGULATOR receiver
Gferi_RS21495	COG5002	protein histidine kinase activity
Gferi_RS21525	COG3693	PFAM glycoside hydrolase, family 10
Gferi_RS21550	COG1902	pentaerythritol trinitrate reductase activity
Gferi_RS21555	COG1028	Short-chain dehydrogenase reductase Sdr
Gferi_RS21565	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Gferi_RS21670	COG3706	GGDEF domain
Gferi_RS21710	COG2207	Transcriptional regulator
Gferi_RS21710	COG3708	Transcriptional regulator
Gferi_RS21715	COG0789	Transcriptional regulator
Gferi_RS21735	COG4195	phage-related replication protein
Gferi_RS21740	COG4195	phage-related replication protein
Gferi_RS21745	COG0791	NLP P60 protein
Gferi_RS21750	COG5002	protein histidine kinase activity
Gferi_RS21755	COG0745	RESPONSE REGULATOR receiver
Gferi_RS21760	COG0789	Transcriptional regulator
Gferi_RS21765	COG1131	(ABC) transporter
Gferi_RS21795	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Gferi_RS21810	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Gferi_RS21820	COG2201	protein-glutamate methylesterase activity
Gferi_RS21840	COG0747	negative chemotaxis
Gferi_RS21845	COG0601	transmembrane transport
Gferi_RS21850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Gferi_RS21855	COG0444	Belongs to the ABC transporter superfamily
Gferi_RS21860	COG4608	Belongs to the ABC transporter superfamily
Gferi_RS21870	COG1309	transcriptional regulator
Gferi_RS21875	COG0574	Belongs to the PEP-utilizing enzyme family
Gferi_RS21875	COG3848	Pyruvate phosphate dikinase
Gferi_RS21910	COG2207	Transcriptional regulator
Gferi_RS21910	COG3708	Transcriptional regulator
Gferi_RS21930	COG0534	Mate efflux family protein
Gferi_RS21935	COG2508	Transcriptional regulator
Gferi_RS21970	COG1309	transcriptional regulator
Gferi_RS21975	COG3848	Pyruvate phosphate dikinase
Gferi_RS21975	COG0574	Belongs to the PEP-utilizing enzyme family
Gferi_RS21990	COG2076	Multidrug Resistance protein
Gferi_RS22005	COG2197	response regulator
Gferi_RS22035	COG2832	Protein of unknown function (DUF454)
Gferi_RS22080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Gferi_RS22085	COG2186	Transcriptional regulator
Gferi_RS22100	COG0745	RESPONSE REGULATOR receiver
Gferi_RS22105	COG5002	protein histidine kinase activity
Gferi_RS22115	COG0577	efflux transmembrane transporter activity
Gferi_RS22120	COG1136	(ABC) transporter
Gferi_RS22125	COG1175	transmembrane transport
Gferi_RS22130	COG0395	ABC-type sugar transport system, permease component
Gferi_RS22150	COG3842	ATPase activity
Gferi_RS22180	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Gferi_RS22215	COG3848	Pyruvate phosphate dikinase
Gferi_RS22215	COG0574	Belongs to the PEP-utilizing enzyme family
Gferi_RS22225	COG1595	DNA-templated transcription, initiation
Gferi_RS22240	COG2207	Transcriptional regulator
Gferi_RS22245	COG2375	cellular response to nickel ion
Gferi_RS22245	COG1132	(ABC) transporter
Gferi_RS22250	COG1132	(ABC) transporter
Gferi_RS22275	COG1129	ABC transporter
Gferi_RS22280	COG1132	(ABC) transporter
Gferi_RS22280	COG2375	cellular response to nickel ion
Gferi_RS22290	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Gferi_RS22295	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Gferi_RS22305	COG2207	Transcriptional regulator
Gferi_RS22315	COG0473	3-isopropylmalate dehydrogenase activity
Gferi_RS22315	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Gferi_RS22320	COG4948	Mandelate Racemase Muconate Lactonizing
Gferi_RS22325	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Gferi_RS22330	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Gferi_RS22335	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Gferi_RS22345	COG1028	Short-chain dehydrogenase reductase Sdr
Gferi_RS22350	COG1063	alcohol dehydrogenase
Gferi_RS22370	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Gferi_RS22375	COG1122	ATPase activity
Gferi_RS22380	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Gferi_RS22385	COG0163	prenyltransferase activity
Gferi_RS22400	COG2198	Histidine kinase
Gferi_RS22400	COG5002	protein histidine kinase activity
Gferi_RS22400	COG0784	Response regulator, receiver
Gferi_RS22410	COG0745	RESPONSE REGULATOR receiver
Gferi_RS22415	COG5002	protein histidine kinase activity
Gferi_RS22420	COG1288	antiporter activity
Gferi_RS22435	COG2502	aspartate--ammonia ligase
Gferi_RS22455	COG1758	RNA polymerase activity
Gferi_RS22460	COG0789	Transcriptional regulator
Gferi_RS22490	COG1396	sequence-specific DNA binding
Gferi_RS22495	COG4166	transmembrane transport
Gferi_RS22500	COG0601	transmembrane transport
Gferi_RS22505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Gferi_RS22510	COG0444	Belongs to the ABC transporter superfamily
Gferi_RS22515	COG4608	Belongs to the ABC transporter superfamily
Gferi_RS22520	COG0006	proline dipeptidase activity
Gferi_RS22525	COG0006	proline dipeptidase activity
Gferi_RS22535	COG4948	Mandelate Racemase Muconate Lactonizing
Gferi_RS22540	COG4948	Mandelate Racemase Muconate Lactonizing
Gferi_RS22545	COG1288	antiporter activity
Gferi_RS22560	COG0745	RESPONSE REGULATOR receiver
Gferi_RS22570	COG1136	(ABC) transporter
Gferi_RS22575	COG0577	efflux transmembrane transporter activity
Gferi_RS22580	COG4977	sequence-specific DNA binding
Gferi_RS22580	COG1917	Cupin 2, conserved barrel domain protein
Gferi_RS22590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Gferi_RS22595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Gferi_RS22630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Gferi_RS22645	COG3959	Transketolase, thiamine diphosphate binding domain
Gferi_RS22650	COG3958	Transketolase
Gferi_RS22665	COG1649	PFAM Uncharacterised BCR, COG1649
Gferi_RS22670	COG2364	Membrane
Gferi_RS22675	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Gferi_RS22685	COG2884	Cell division ATP-binding protein ftsE
Gferi_RS22695	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
Gferi_RS22700	COG3711	transcriptional antiterminator
Gferi_RS22700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Gferi_RS22715	COG1840	ABC-type Fe3 transport system, periplasmic component
Gferi_RS22725	COG3842	ATPase activity
Gferi_RS22730	COG1285	pathogenesis
Gferi_RS22735	COG1840	ABC-type Fe3 transport system, periplasmic component
Gferi_RS22785	COG0488	(ABC) transporter
Gferi_RS22825	COG2186	Transcriptional regulator
Gferi_RS22860	COG1028	Short-chain dehydrogenase reductase Sdr
Gferi_RS22865	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
Gferi_RS22880	COG3411	Ferredoxin
Gferi_RS22905	COG0460	homoserine dehydrogenase
Gferi_RS22915	COG1690	Belongs to the RtcB family
Gferi_RS22935	COG1773	rubredoxin
Gferi_RS22960	COG1376	ErfK ybiS ycfS ynhG family protein
Gferi_RS22975	COG2235	arginine
Gferi_RS22980	COG0482	sulfurtransferase activity
Gferi_RS22985	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Gferi_RS23000	COG0840	transmembrane signaling receptor activity
Gferi_RS23010	COG0367	asparagine synthase
Gferi_RS23025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Gferi_RS23040	COG3773	Cell wall hydrolase
Gferi_RS23055	COG2362	D-Aminopeptidase
Gferi_RS23065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Gferi_RS23070	COG1940	carbohydrate kinase activity
Gferi_RS23075	COG0166	Belongs to the GPI family
Gferi_RS23080	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Gferi_RS23095	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Gferi_RS23105	COG0778	Nitroreductase
Gferi_RS23110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Gferi_RS23120	COG3279	Response regulator of the LytR AlgR family
Gferi_RS23130	COG1666	GTP binding
Gferi_RS23135	COG0697	spore germination
Gferi_RS23150	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Gferi_RS23165	COG1278	Cold shock
Gferi_RS23190	COG1242	4 iron, 4 sulfur cluster binding
Gferi_RS23195	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Gferi_RS23215	COG2154	pterin-4-alpha-carbinolamine dehydratase
Gferi_RS23235	COG2357	RelA SpoT domain protein
Gferi_RS23265	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Gferi_RS23290	COG2339	peptidase activity
Gferi_RS23330	COG0346	lactoylglutathione lyase activity
Gferi_RS23390	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Gferi_RS23395	COG3546	catalase activity
Gferi_RS23415	COG0840	transmembrane signaling receptor activity
Gferi_RS23420	COG2234	aminopeptidase activity
Gferi_RS23445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Gferi_RS23450	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Gferi_RS23450	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
Gferi_RS23545	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Gferi_RS23580	COG4626	Terminase
Gferi_RS23580	COG1802	Transcriptional regulator
Gferi_RS23585	COG4695	Portal protein
Gferi_RS23665	COG4824	toxin secretion phage lysis holin
Gferi_RS23670	COG0791	NLP P60 protein
Gferi_RS23670	COG1388	LysM domain
Gferi_RS23695	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Gferi_RS23695	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Gferi_RS23725	COG2217	Heavy metal translocating P-type atpase
Gferi_RS23730	COG2217	Heavy metal translocating P-type atpase
Gferi_RS23735	COG2217	Heavy metal translocating P-type atpase
Gferi_RS23755	COG0596	Alpha beta hydrolase
Gferi_RS23760	COG0534	Mate efflux family protein
Gferi_RS23765	COG2226	methyltransferase
Gferi_RS23795	COG1695	Transcriptional regulator
Gferi_RS23835	COG0640	Transcriptional regulator
Gferi_RS23855	COG0697	spore germination
Gferi_RS23885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Gferi_RS23890	COG2855	membrane
Gferi_RS23895	COG0583	DNA-binding transcription factor activity
Gferi_RS23920	COG0300	oxidoreductase activity
Gferi_RS23940	COG1595	DNA-templated transcription, initiation
Gferi_RS23945	COG1917	Cupin 2, conserved barrel domain protein
Gferi_RS23975	COG2816	NAD+ diphosphatase activity
Gferi_RS24000	COG2217	Heavy metal translocating P-type atpase
Gferi_RS24010	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Gferi_RS24015	COG0534	Mate efflux family protein
Gferi_RS24020	COG0191	fructose-bisphosphate aldolase activity
Gferi_RS24025	COG0688	phosphatidylethanolamine metabolic process
Gferi_RS24030	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Gferi_RS24035	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
Gferi_RS24035	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Gferi_RS24040	COG1187	pseudouridine synthase activity
Gferi_RS24065	COG0681	Belongs to the peptidase S26 family
Gferi_RS24070	COG0517	IMP dehydrogenase activity
Gferi_RS24075	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Gferi_RS24080	COG2066	Belongs to the glutaminase family
Gferi_RS24100	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Gferi_RS24110	COG0681	Belongs to the peptidase S26 family
Gferi_RS24130	COG1115	amino acid carrier protein
Gferi_RS24140	COG1067	ATP-dependent peptidase activity
Gferi_RS24145	COG0156	8-amino-7-oxononanoate synthase activity
Gferi_RS24155	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Gferi_RS24170	COG2720	vancomycin resistance protein
Gferi_RS24180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Gferi_RS24190	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
Gferi_RS24195	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
Gferi_RS24200	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Gferi_RS24205	COG0588	phosphoglycerate mutase activity
Gferi_RS24210	COG1797	cobyrinic acid a,c-diamide synthase activity
Gferi_RS24215	COG1492	cobalamin metabolic process
Gferi_RS24225	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Gferi_RS24245	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
Gferi_RS24275	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Gferi_RS24290	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Gferi_RS24290	COG1648	precorrin-2 dehydrogenase activity
Gferi_RS24295	COG0181	hydroxymethylbilane synthase activity
Gferi_RS24305	COG0113	porphobilinogen synthase activity
Gferi_RS24310	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Gferi_RS24315	COG0653	protein targeting
Gferi_RS24320	COG0714	Associated with various cellular activities
Gferi_RS24330	COG1305	Transglutaminase-like
Gferi_RS24335	COG0735	belongs to the Fur family
Gferi_RS24340	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
Gferi_RS24350	COG1406	Chemotaxis phosphatase CheX
Gferi_RS24360	COG1283	sodium-dependent phosphate transmembrane transporter activity
Gferi_RS24370	COG1307	EDD domain protein, DegV family
Gferi_RS24375	COG1307	EDD domain protein, DegV family
Gferi_RS24430	COG1744	ABC transporter substrate-binding protein PnrA-like
Gferi_RS24435	COG3845	ABC transporter
Gferi_RS24440	COG4603	Belongs to the binding-protein-dependent transport system permease family
Gferi_RS24445	COG1079	Belongs to the binding-protein-dependent transport system permease family
Gferi_RS24450	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Gferi_RS24455	COG2390	Transcriptional regulator
Gferi_RS24465	COG0126	phosphoglycerate kinase activity
Gferi_RS24470	COG0149	triose-phosphate isomerase activity
Gferi_RS24475	COG0148	phosphopyruvate hydratase activity
Gferi_RS24480	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Gferi_RS24495	COG0557	exoribonuclease II activity
Gferi_RS24500	COG0561	phosphatase activity
Gferi_RS24535	COG2361	Protein of unknown function DUF86
Gferi_RS24540	COG0745	RESPONSE REGULATOR receiver
Gferi_RS24545	COG5002	protein histidine kinase activity
Gferi_RS24560	COG0745	RESPONSE REGULATOR receiver
Gferi_RS24565	COG5002	protein histidine kinase activity
Gferi_RS24570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Gferi_RS24580	COG0577	efflux transmembrane transporter activity
Gferi_RS24585	COG1136	(ABC) transporter
Gferi_RS24600	COG1737	Transcriptional regulator
Gferi_RS24610	COG1175	transmembrane transport
Gferi_RS24620	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Gferi_RS24625	COG2971	BadF BadG BcrA BcrD
Gferi_RS24670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Gferi_RS24695	COG0626	cystathionine gamma-synthase activity
Gferi_RS24700	COG3022	response to hydroperoxide
Gferi_RS24715	COG0596	Alpha beta hydrolase
Gferi_RS24755	COG1476	TRANSCRIPTIONal
Gferi_RS24785	COG0601	transmembrane transport
Gferi_RS24790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Gferi_RS24800	COG0444	Belongs to the ABC transporter superfamily
Gferi_RS24805	COG4608	Belongs to the ABC transporter superfamily
Gferi_RS24810	COG0747	negative chemotaxis
Gferi_RS24815	COG0601	transmembrane transport
Gferi_RS24820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Gferi_RS24825	COG1126	abc transporter atp-binding protein
Gferi_RS24835	COG0613	PHP domain protein
Gferi_RS24845	COG0662	Cupin 2, conserved barrel domain protein
Gferi_RS24850	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Gferi_RS24855	COG0402	S-adenosylhomocysteine deaminase activity
Gferi_RS24865	COG1151	hydroxylamine reductase activity
Gferi_RS24875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Gferi_RS24890	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Gferi_RS24895	COG0022	dehydrogenase e1 component
Gferi_RS24900	COG3199	ATP-NAD kinase
Gferi_RS24905	COG0508	dehydrogenase complex catalyzes the overall conversion of
Gferi_RS24925	COG5002	protein histidine kinase activity
Gferi_RS24930	COG0745	RESPONSE REGULATOR receiver
Gferi_RS24960	COG2843	Capsule synthesis protein
Gferi_RS24965	COG2226	methyltransferase
Gferi_RS24985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Gferi_RS24990	COG2169	Transcriptional regulator
Gferi_RS24995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Gferi_RS25000	COG0626	cystathionine gamma-synthase activity
Gferi_RS25005	COG3711	transcriptional antiterminator
Gferi_RS25010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Gferi_RS25010	COG2190	(PTS) system
Gferi_RS25010	COG1263	PTS System
Gferi_RS25015	COG2190	(PTS) system
Gferi_RS25015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Gferi_RS25015	COG1263	PTS System
Gferi_RS25020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Gferi_RS25025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Gferi_RS25050	COG2080	2 iron, 2 sulfur cluster binding
Gferi_RS25050	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Gferi_RS25095	COG0582	viral genome integration into host DNA
Gferi_RS25105	COG0655	NAD(P)H dehydrogenase (quinone) activity
Gferi_RS25120	COG0583	DNA-binding transcription factor activity
Gferi_RS25125	COG1288	antiporter activity
Gferi_RS25140	COG0003	Pfam Anion-transporting ATPase
Gferi_RS25150	COG0003	Pfam Anion-transporting ATPase
Gferi_RS25160	COG0330	HflC and HflK could
Gferi_RS25165	COG1522	sequence-specific DNA binding
Gferi_RS25170	COG0511	ligase activity, forming carbon-carbon bonds
Gferi_RS25170	COG5016	pyruvate
Gferi_RS25180	COG0242	peptide deformylase activity
Gferi_RS25195	COG0747	negative chemotaxis
Gferi_RS25200	COG0601	transmembrane transport
Gferi_RS25205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Gferi_RS25210	COG0444	Belongs to the ABC transporter superfamily
Gferi_RS25215	COG4608	Belongs to the ABC transporter superfamily
Gferi_RS25230	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
Gferi_RS25245	COG1609	Transcriptional regulator
Gferi_RS25250	COG1879	ABC-type sugar transport system periplasmic component
Gferi_RS25255	COG1129	ABC transporter
Gferi_RS25260	COG1172	Belongs to the binding-protein-dependent transport system permease family
Gferi_RS25265	COG0673	inositol 2-dehydrogenase activity
Gferi_RS25275	COG0321	lipoyl(octanoyl) transferase activity
Gferi_RS25280	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Gferi_RS25295	COG0281	malic enzyme
Gferi_RS25300	COG3875	lactate racemase activity
Gferi_RS25305	COG1024	Enoyl-CoA hydratase
Gferi_RS25310	COG0372	Belongs to the citrate synthase family
Gferi_RS25315	COG0473	3-isopropylmalate dehydrogenase activity
Gferi_RS25320	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Gferi_RS25325	COG3829	transcription factor binding
Gferi_RS25330	COG2986	histidine ammonia-lyase
Gferi_RS25335	COG2358	TRAP transporter, solute receptor (TAXI family
Gferi_RS25350	COG1757	Na H antiporter
Gferi_RS25355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Gferi_RS25370	COG0037	tRNA processing
Gferi_RS25400	COG1418	mRNA catabolic process
Gferi_RS25410	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Gferi_RS25420	COG0302	gtp cyclohydrolase
Gferi_RS25425	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Gferi_RS25430	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Gferi_RS25435	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Gferi_RS25480	COG2205	protein histidine kinase activity
Gferi_RS25485	COG0745	RESPONSE REGULATOR receiver
Gferi_RS25505	COG1940	carbohydrate kinase activity
Gferi_RS25510	COG4213	ABC transporter substrate-binding protein
Gferi_RS25520	COG4214	carbohydrate transport
Gferi_RS25525	COG0363	glucosamine-6-phosphate deaminase activity
Gferi_RS25530	COG0674	pyruvate-flavodoxin oxidoreductase activity
Gferi_RS25530	COG1013	pyruvate-flavodoxin oxidoreductase activity
Gferi_RS25530	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Gferi_RS25530	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Gferi_RS25545	COG0612	Peptidase, M16
Gferi_RS25555	COG5001	Diguanylate cyclase
Gferi_RS25555	COG3447	MASE1 domain protein
Gferi_RS25555	COG5002	protein histidine kinase activity
Gferi_RS25560	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Gferi_RS25565	COG3191	aminopeptidase activity
Gferi_RS25570	COG0217	transcriptional regulatory protein
Gferi_RS25595	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Gferi_RS25605	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Gferi_RS25605	COG3933	PFAM sigma-54 factor interaction domain-containing protein
Gferi_RS25610	COG3711	transcriptional antiterminator
Gferi_RS25610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Gferi_RS25620	COG3775	system Galactitol-specific IIC component
Gferi_RS25625	COG1063	alcohol dehydrogenase
Gferi_RS25635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Gferi_RS25640	COG1070	Carbohydrate kinase
Gferi_RS25650	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Gferi_RS25650	COG3933	PFAM sigma-54 factor interaction domain-containing protein
Gferi_RS25655	COG2213	PTS system mannitol-specific
Gferi_RS25655	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Gferi_RS25660	COG3414	Phosphotransferase system galactitol-specific IIB component
Gferi_RS25665	COG3775	system Galactitol-specific IIC component
Gferi_RS25680	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Gferi_RS25690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Gferi_RS25705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Gferi_RS25725	COG1285	pathogenesis
Gferi_RS25730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Gferi_RS25745	COG2323	membrane
Gferi_RS25755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Gferi_RS25790	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Gferi_RS25795	COG0860	N-Acetylmuramoyl-L-alanine amidase
Gferi_RS25820	COG0124	histidyl-tRNA synthetase
Gferi_RS25825	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Gferi_RS25830	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Gferi_RS25835	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Gferi_RS25840	COG0131	Imidazoleglycerol-phosphate dehydratase
Gferi_RS25845	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Gferi_RS25850	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Gferi_RS25855	COG0107	imidazoleglycerol-phosphate synthase activity
Gferi_RS25860	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Gferi_RS25860	COG0140	phosphoribosyl-ATP diphosphatase activity
Gferi_RS25865	COG3275	phosphorelay sensor kinase activity
Gferi_RS25875	COG3852	Histidine kinase
Gferi_RS25880	COG2204	response regulator
Gferi_RS25890	COG0437	4 iron, 4 sulfur cluster binding
Gferi_RS25895	COG2414	aldehyde ferredoxin oxidoreductase
Gferi_RS25905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Gferi_RS25910	COG0686	Belongs to the AlaDH PNT family
Gferi_RS25920	COG0739	heme binding
Gferi_RS25920	COG0741	lytic transglycosylase activity
Gferi_RS25920	COG1196	nuclear chromosome segregation
Gferi_RS25930	COG1846	Transcriptional regulator
Gferi_RS25935	COG3706	GGDEF domain
Gferi_RS25955	COG2986	histidine ammonia-lyase
Gferi_RS25960	COG4224	UPF0291 protein
Gferi_RS25965	COG0835	chemotaxis
Gferi_RS25985	COG1362	aminopeptidase activity
Gferi_RS25990	COG0583	DNA-binding transcription factor activity
Gferi_RS25995	COG2865	translation initiation factor activity
Gferi_RS26005	COG2972	Histidine kinase
Gferi_RS26010	COG2197	response regulator
Gferi_RS26060	COG4869	propanediol catabolic process
Gferi_RS26065	COG4820	ethanolamine utilization protein (EutJ)
Gferi_RS26075	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
Gferi_RS26090	COG4656	Part of a membrane complex involved in electron transport
Gferi_RS26110	COG1988	membrane-bound metal-dependent
Gferi_RS26115	COG1376	ErfK ybiS ycfS ynhG family protein
Gferi_RS26120	COG1595	DNA-templated transcription, initiation
Gferi_RS26130	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Gferi_RS26130	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Gferi_RS26135	COG0237	dephospho-CoA kinase activity
Gferi_RS26150	COG0747	negative chemotaxis
Gferi_RS26175	COG0791	NLP P60 protein
Gferi_RS26180	COG0741	lytic transglycosylase activity
Gferi_RS26215	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Gferi_RS26220	COG4656	Part of a membrane complex involved in electron transport
Gferi_RS26225	COG4658	electron transport chain
Gferi_RS26230	COG4659	FMN binding
Gferi_RS26235	COG4660	Part of a membrane complex involved in electron transport
Gferi_RS26240	COG4657	Part of a membrane complex involved in electron transport
Gferi_RS26245	COG1245	4Fe-4S binding domain
Gferi_RS26245	COG2878	Part of a membrane complex involved in electron transport
Gferi_RS26265	COG0424	maF-like protein
Gferi_RS26270	COG2003	Belongs to the UPF0758 family
Gferi_RS26275	COG1077	Cell shape determining protein MreB Mrl
Gferi_RS26295	COG0850	regulation of cytokinetic process
Gferi_RS26300	COG2894	cell division
Gferi_RS26305	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Gferi_RS26310	COG1803	Methylglyoxal synthase
Gferi_RS26315	COG1252	NADH dehydrogenase
Gferi_RS26320	COG1477	protein flavinylation
Gferi_RS26325	COG0142	geranyltranstransferase activity
Gferi_RS26335	COG1994	Peptidase M50
Gferi_RS26340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Gferi_RS26355	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Gferi_RS26360	COG2868	ribosomal protein
Gferi_RS26365	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Gferi_RS26370	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Gferi_RS26380	COG1534	Rna-binding protein
Gferi_RS26395	COG1713	HD superfamily hydrolase involved in NAD metabolism
Gferi_RS26400	COG1316	TRANSCRIPTIONal
Gferi_RS26410	COG0799	negative regulation of ribosome biogenesis
Gferi_RS26420	COG0251	oxidation-reduction process
Gferi_RS26425	COG1760	l-serine dehydratase
Gferi_RS26430	COG1760	l-serine dehydratase
Gferi_RS26435	COG1686	Belongs to the peptidase S11 family
Gferi_RS26440	COG1596	polysaccharide export
Gferi_RS26440	COG1555	photosystem II stabilization
Gferi_RS26445	COG0709	Synthesizes selenophosphate from selenide and ATP
Gferi_RS26450	COG1921	L-seryl-tRNASec selenium transferase activity
Gferi_RS26460	COG0745	RESPONSE REGULATOR receiver
Gferi_RS26465	COG5002	protein histidine kinase activity
Gferi_RS26535	COG2003	Belongs to the UPF0758 family
Gferi_RS26575	COG0582	viral genome integration into host DNA
Gferi_RS26595	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Gferi_RS26600	COG0632	four-way junction helicase activity
Gferi_RS26605	COG2255	four-way junction helicase activity
Gferi_RS26615	COG2385	sporulation resulting in formation of a cellular spore
Gferi_RS26615	COG2247	cell wall binding repeat
Gferi_RS26625	COG0343	queuine tRNA-ribosyltransferase activity
Gferi_RS26630	COG1862	Preprotein translocase
Gferi_RS26655	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Gferi_RS26660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Gferi_RS26670	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Gferi_RS26675	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Gferi_RS26680	COG1490	D-aminoacyl-tRNA deacylase activity
Gferi_RS26685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Gferi_RS26695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Gferi_RS26700	COG0124	histidyl-tRNA synthetase
Gferi_RS26705	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Gferi_RS26725	COG2966	Psort location CytoplasmicMembrane, score
Gferi_RS26730	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Gferi_RS26735	COG3829	transcription factor binding
Gferi_RS26740	COG3804	dihydrodipicolinate reductase
Gferi_RS26750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Gferi_RS26760	COG5012	cobalamin binding
Gferi_RS26770	COG3457	Alanine racemase
Gferi_RS26790	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Gferi_RS26810	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Gferi_RS26815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Gferi_RS26820	COG1959	2 iron, 2 sulfur cluster binding
Gferi_RS26830	COG0822	iron-sulfur transferase activity
Gferi_RS26835	COG0482	sulfurtransferase activity
Gferi_RS26840	COG3881	PFAM PRC-barrel domain
Gferi_RS26850	COG0628	permease
Gferi_RS26855	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Gferi_RS26860	COG4472	Bacterial protein of unknown function (DUF965)
Gferi_RS26870	COG0667	Aldo Keto reductase
Gferi_RS26875	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Gferi_RS26880	COG3906	Belongs to the UPF0473 family
Gferi_RS26885	COG1489	DNA binding
Gferi_RS26890	COG0735	belongs to the Fur family
Gferi_RS26895	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Gferi_RS26910	COG3679	Belongs to the UPF0342 family
Gferi_RS26915	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Gferi_RS26920	COG4122	O-methyltransferase activity
Gferi_RS26925	COG0826	peptidase U32
Gferi_RS26930	COG0572	uridine kinase
Gferi_RS26935	COG0768	penicillin binding
Gferi_RS26945	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Gferi_RS26965	COG0772	Belongs to the SEDS family
Gferi_RS26970	COG2843	Capsule synthesis protein
Gferi_RS26975	COG1408	metallophosphoesterase
Gferi_RS26995	COG0745	RESPONSE REGULATOR receiver
Gferi_RS27000	COG5002	protein histidine kinase activity
Gferi_RS27005	COG1442	glycosyl transferase family 8
Gferi_RS27005	COG1216	Glycosyl transferase, family 2
Gferi_RS27015	COG0562	UDP-galactopyranose mutase
Gferi_RS27025	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Gferi_RS27050	COG0714	Associated with various cellular activities
Gferi_RS27065	COG1714	RDD family
Gferi_RS27085	COG0644	oxidoreductase
Gferi_RS27120	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
Gferi_RS27130	COG0697	spore germination
Gferi_RS27135	COG0456	acetyltransferase
Gferi_RS27135	COG1846	Transcriptional regulator
Gferi_RS27140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Gferi_RS27145	COG1028	Short-chain dehydrogenase reductase Sdr
Gferi_RS27155	COG0321	lipoyl(octanoyl) transferase activity
Gferi_RS27160	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
Gferi_RS27165	COG2323	membrane
Gferi_RS27170	COG4974	Belongs to the 'phage' integrase family
Gferi_RS27175	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Gferi_RS27180	COG0017	Asparaginyl-tRNA synthetase
Gferi_RS27190	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Gferi_RS27195	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
Gferi_RS27210	COG0464	growth
Gferi_RS27215	COG1923	regulation of RNA biosynthetic process
Gferi_RS27220	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Gferi_RS27225	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Gferi_RS27230	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Gferi_RS27235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine