locus-tag	class	description
GNIT_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GNIT_RS00045	COG2818	Glycosylase
GNIT_RS00055	COG3078	GTPase activator activity
GNIT_RS00075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GNIT_RS00080	COG0569	domain protein
GNIT_RS00085	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GNIT_RS00085	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GNIT_RS00105	COG0758	DNA mediated transformation
GNIT_RS00120	COG0009	L-threonylcarbamoyladenylate synthase
GNIT_RS00125	COG0408	coproporphyrinogen oxidase activity
GNIT_RS00130	COG3047	cAMP biosynthetic process
GNIT_RS00140	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GNIT_RS00145	COG1280	lysine exporter protein (LysE YggA)
GNIT_RS00180	COG0745	RESPONSE REGULATOR receiver
GNIT_RS00220	COG2234	aminopeptidase activity
GNIT_RS00230	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GNIT_RS00240	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GNIT_RS00245	COG2003	Belongs to the UPF0758 family
GNIT_RS00255	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GNIT_RS00260	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GNIT_RS00275	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GNIT_RS00290	COG3642	lipopolysaccharide core region biosynthetic process
GNIT_RS00295	COG0859	PFAM glycosyl transferase family 9
GNIT_RS00300	COG0156	8-amino-7-oxononanoate synthase activity
GNIT_RS00310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GNIT_RS00315	COG0705	Rhomboid family
GNIT_RS00330	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GNIT_RS00340	COG0210	DNA helicase
GNIT_RS00365	COG2252	PERMEase
GNIT_RS00370	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GNIT_RS00385	COG0417	DNA replication proofreading
GNIT_RS00390	COG2197	response regulator
GNIT_RS00395	COG5002	protein histidine kinase activity
GNIT_RS00395	COG2198	Histidine kinase
GNIT_RS00395	COG0784	Response regulator, receiver
GNIT_RS00405	COG0778	Nitroreductase
GNIT_RS00410	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GNIT_RS00410	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GNIT_RS00420	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GNIT_RS00425	COG4136	ATPase activity
GNIT_RS00430	COG4135	transport system, permease component
GNIT_RS00435	COG4134	Bacterial extracellular solute-binding protein
GNIT_RS00465	COG0596	Alpha beta hydrolase
GNIT_RS00475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GNIT_RS00485	COG1960	acyl-CoA dehydrogenase activity
GNIT_RS00495	COG1024	Enoyl-CoA hydratase
GNIT_RS00500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GNIT_RS00505	COG2272	Belongs to the type-B carboxylesterase lipase family
GNIT_RS00510	COG1960	acyl-CoA dehydrogenase activity
GNIT_RS00515	COG1960	acyl-CoA dehydrogenase activity
GNIT_RS00530	COG0346	lactoylglutathione lyase activity
GNIT_RS00535	COG0318	PFAM AMP-dependent synthetase and ligase
GNIT_RS00540	COG0183	Belongs to the thiolase family
GNIT_RS00545	COG1024	Enoyl-CoA hydratase
GNIT_RS00545	COG1250	3-hydroxyacyl-CoA dehydrogenase
GNIT_RS00560	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GNIT_RS00560	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GNIT_RS00580	COG0583	DNA-binding transcription factor activity
GNIT_RS00585	COG1960	acyl-CoA dehydrogenase activity
GNIT_RS00590	COG3706	GGDEF domain
GNIT_RS00595	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GNIT_RS00605	COG2326	polyphosphate kinase activity
GNIT_RS00630	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GNIT_RS00635	COG4988	ABC transporter
GNIT_RS00645	COG1271	oxidase subunit
GNIT_RS00655	COG2072	flavoprotein involved in K transport
GNIT_RS00675	COG2814	Major facilitator Superfamily
GNIT_RS00680	COG3153	acetyltransferase
GNIT_RS00680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GNIT_RS00685	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GNIT_RS00690	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GNIT_RS00700	COG4152	abc transporter atp-binding protein
GNIT_RS00715	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GNIT_RS00725	COG1505	serine-type exopeptidase activity
GNIT_RS00735	COG4948	Mandelate Racemase Muconate Lactonizing
GNIT_RS00745	COG1028	Short-chain dehydrogenase reductase Sdr
GNIT_RS00795	COG0823	Involved in the tonB-independent uptake of proteins
GNIT_RS00795	COG1506	peptidase
GNIT_RS00795	COG4946	Tricorn protease homolog
GNIT_RS00830	COG0564	pseudouridine synthase activity
GNIT_RS00865	COG0589	response to stress
GNIT_RS00875	COG1764	response to oxidative stress
GNIT_RS00885	COG1028	Short-chain dehydrogenase reductase Sdr
GNIT_RS00890	COG1022	Amp-dependent synthetase and ligase
GNIT_RS00900	COG0596	Alpha beta hydrolase
GNIT_RS00910	COG5001	Diguanylate cyclase
GNIT_RS00910	COG4251	negative regulation of phosphorylation
GNIT_RS00910	COG3706	GGDEF domain
GNIT_RS00910	COG2203	Gaf domain
GNIT_RS00930	COG2373	Large extracellular alpha-helical protein
GNIT_RS00935	COG4953	penicillin-binding protein 1C
GNIT_RS00965	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GNIT_RS00980	COG2959	enzyme of heme biosynthesis
GNIT_RS00990	COG0181	hydroxymethylbilane synthase activity
GNIT_RS01000	COG0194	GDP metabolic process
GNIT_RS01010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GNIT_RS01020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GNIT_RS01030	COG3706	GGDEF domain
GNIT_RS01030	COG4251	negative regulation of phosphorylation
GNIT_RS01030	COG2203	Gaf domain
GNIT_RS01030	COG5001	Diguanylate cyclase
GNIT_RS01040	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GNIT_RS01045	COG0742	ribosomal rna small subunit methyltransferase
GNIT_RS01055	COG2081	HI0933 family
GNIT_RS01060	COG5001	Diguanylate cyclase
GNIT_RS01075	COG3250	beta-galactosidase activity
GNIT_RS01095	COG0183	Belongs to the thiolase family
GNIT_RS01100	COG0640	Transcriptional regulator
GNIT_RS01110	COG0431	NADPH-dependent FMN reductase
GNIT_RS01115	COG0798	PFAM Bile acid sodium symporter
GNIT_RS01140	COG2308	Evidence 4 Homologs of previously reported genes of
GNIT_RS01150	COG0754	glutathionylspermidine amidase activity
GNIT_RS01170	COG2066	Belongs to the glutaminase family
GNIT_RS01185	COG0625	glutathione transferase activity
GNIT_RS01205	COG1231	oxidoreductase activity
GNIT_RS01220	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GNIT_RS01250	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GNIT_RS01255	COG0315	cyclic pyranopterin monophosphate synthase activity
GNIT_RS01260	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GNIT_RS01280	COG3064	Membrane
GNIT_RS01285	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GNIT_RS01285	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
GNIT_RS01290	COG5001	Diguanylate cyclase
GNIT_RS01290	COG5002	protein histidine kinase activity
GNIT_RS01295	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GNIT_RS01310	COG0514	ATP-dependent DNA helicase (RecQ)
GNIT_RS01325	COG2962	Rard protein
GNIT_RS01335	COG0457	Tetratricopeptide repeat
GNIT_RS01350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GNIT_RS01370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GNIT_RS01385	COG4681	YaeQ
GNIT_RS01400	COG0709	Synthesizes selenophosphate from selenide and ATP
GNIT_RS01405	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GNIT_RS01410	COG0210	DNA helicase
GNIT_RS01420	COG0443	Heat shock 70 kDa protein
GNIT_RS01425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GNIT_RS01440	COG0446	pyridine nucleotide-disulphide oxidoreductase
GNIT_RS01440	COG1902	pentaerythritol trinitrate reductase activity
GNIT_RS01450	COG1011	Hydrolase
GNIT_RS01465	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GNIT_RS01470	COG0019	diaminopimelate decarboxylase activity
GNIT_RS01495	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GNIT_RS01500	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GNIT_RS01505	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GNIT_RS01515	COG0840	transmembrane signaling receptor activity
GNIT_RS01520	COG2205	protein histidine kinase activity
GNIT_RS01520	COG0784	Response regulator, receiver
GNIT_RS01540	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GNIT_RS01545	COG2814	Major facilitator Superfamily
GNIT_RS01550	COG0629	single-stranded DNA binding
GNIT_RS01585	COG3267	Type II secretory pathway component ExeA
GNIT_RS01585	COG3409	Peptidoglycan-binding domain 1 protein
GNIT_RS01595	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GNIT_RS01600	COG1459	type II secretion system
GNIT_RS01610	COG2165	general secretion pathway protein
GNIT_RS01615	COG2165	general secretion pathway protein
GNIT_RS01645	COG1077	Cell shape determining protein MreB Mrl
GNIT_RS01650	COG1792	Involved in formation and maintenance of cell shape
GNIT_RS01655	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GNIT_RS01660	COG0424	maF-like protein
GNIT_RS01665	COG1530	ribonuclease E activity
GNIT_RS01675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GNIT_RS01680	COG0312	modulator of DNA gyrase
GNIT_RS01700	COG0745	RESPONSE REGULATOR receiver
GNIT_RS01705	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GNIT_RS01730	COG0826	peptidase U32
GNIT_RS01750	COG0051	transcription antitermination factor activity, RNA binding
GNIT_RS01765	COG0089	rRNA binding
GNIT_RS01775	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GNIT_RS01785	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GNIT_RS01800	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GNIT_RS01805	COG0789	Transcriptional regulator
GNIT_RS01815	COG1519	Transferase
GNIT_RS01820	COG0339	signal peptide processing
GNIT_RS01825	COG2885	chlorophyll binding
GNIT_RS01830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GNIT_RS01835	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GNIT_RS01840	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GNIT_RS01845	COG1970	mechanosensitive ion channel activity
GNIT_RS01850	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GNIT_RS01875	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GNIT_RS01900	COG0142	geranyltranstransferase activity
GNIT_RS01910	COG0788	formyltetrahydrofolate deformylase activity
GNIT_RS01915	COG1028	Short-chain dehydrogenase reductase Sdr
GNIT_RS01920	COG2951	lytic endotransglycosylase activity
GNIT_RS01945	COG3243	poly(R)-hydroxyalkanoic acid synthase
GNIT_RS01955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GNIT_RS01965	COG0004	ammonium transporteR
GNIT_RS01980	COG1063	alcohol dehydrogenase
GNIT_RS01985	COG0708	Exodeoxyribonuclease III
GNIT_RS01990	COG0405	Gamma-glutamyltransferase
GNIT_RS01995	COG2837	iron assimilation
GNIT_RS02010	COG0745	RESPONSE REGULATOR receiver
GNIT_RS02020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GNIT_RS02045	COG4946	Tricorn protease homolog
GNIT_RS02045	COG0793	Belongs to the peptidase S41A family
GNIT_RS02050	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GNIT_RS02065	COG0540	Belongs to the ATCase OTCase family
GNIT_RS02090	COG3437	response regulator, receiver
GNIT_RS02090	COG4999	Histidine kinase
GNIT_RS02090	COG2205	protein histidine kinase activity
GNIT_RS02090	COG3850	Histidine kinase
GNIT_RS02110	COG1136	(ABC) transporter
GNIT_RS02125	COG0189	ligase activity
GNIT_RS02145	COG1012	belongs to the aldehyde dehydrogenase family
GNIT_RS02155	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GNIT_RS02170	COG0180	Tryptophanyl-tRNA synthetase
GNIT_RS02195	COG5001	Diguanylate cyclase
GNIT_RS02195	COG1716	ATPase activity
GNIT_RS02200	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GNIT_RS02205	COG3266	domain, Protein
GNIT_RS02210	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GNIT_RS02245	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GNIT_RS02250	COG0281	malic enzyme
GNIT_RS02255	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GNIT_RS02255	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GNIT_RS02265	COG0137	argininosuccinate synthase activity
GNIT_RS02275	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GNIT_RS02285	COG1803	Methylglyoxal synthase
GNIT_RS02305	COG0745	RESPONSE REGULATOR receiver
GNIT_RS02310	COG2205	protein histidine kinase activity
GNIT_RS02335	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GNIT_RS02340	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GNIT_RS02355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GNIT_RS02360	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GNIT_RS02365	COG4942	peptidase
GNIT_RS02380	COG1981	membrane
GNIT_RS02400	COG0625	glutathione transferase activity
GNIT_RS02410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GNIT_RS02415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GNIT_RS02420	COG0805	protein transport
GNIT_RS02430	COG0084	hydrolase, TatD family'
GNIT_RS02440	COG2203	Gaf domain
GNIT_RS02440	COG3706	GGDEF domain
GNIT_RS02440	COG4251	negative regulation of phosphorylation
GNIT_RS02440	COG5001	Diguanylate cyclase
GNIT_RS02455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GNIT_RS02465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GNIT_RS02470	COG0617	tRNA 3'-terminal CCA addition
GNIT_RS02485	COG1489	DNA binding
GNIT_RS02500	COG2095	MarC family integral membrane protein
GNIT_RS02505	COG3068	Protein conserved in bacteria
GNIT_RS02510	COG0742	ribosomal rna small subunit methyltransferase
GNIT_RS02515	COG0552	protein localization to endoplasmic reticulum
GNIT_RS02520	COG2884	Cell division ATP-binding protein ftsE
GNIT_RS02525	COG2177	Part of the ABC transporter FtsEX involved in
GNIT_RS02535	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GNIT_RS02540	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GNIT_RS02545	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GNIT_RS02555	COG0456	acetyltransferase
GNIT_RS02575	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
GNIT_RS02580	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GNIT_RS02590	COG0069	glutamate synthase activity
GNIT_RS02595	COG3784	Protein of unknown function (DUF1318)
GNIT_RS02610	COG0840	transmembrane signaling receptor activity
GNIT_RS02620	COG0494	nUDIX hydrolase
GNIT_RS02630	COG0730	response to heat
GNIT_RS02635	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GNIT_RS02640	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GNIT_RS02650	COG3706	GGDEF domain
GNIT_RS02665	COG0564	pseudouridine synthase activity
GNIT_RS02670	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GNIT_RS02675	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GNIT_RS02680	COG3706	GGDEF domain
GNIT_RS02680	COG5001	Diguanylate cyclase
GNIT_RS02680	COG2203	Gaf domain
GNIT_RS02680	COG4251	negative regulation of phosphorylation
GNIT_RS02685	COG4771	TonB-dependent receptor
GNIT_RS02690	COG0477	Major facilitator Superfamily
GNIT_RS02700	COG5002	protein histidine kinase activity
GNIT_RS02700	COG0784	Response regulator, receiver
GNIT_RS02715	COG3268	Saccharopine dehydrogenase
GNIT_RS02725	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GNIT_RS02750	COG1217	gtp-binding protein TYPA
GNIT_RS02755	COG2353	YceI-like domain
GNIT_RS02765	COG2353	YceI-like domain
GNIT_RS02770	COG0174	glutamine synthetase
GNIT_RS02780	COG3852	Histidine kinase
GNIT_RS02785	COG2204	response regulator
GNIT_RS02790	COG2203	Gaf domain
GNIT_RS02790	COG3706	GGDEF domain
GNIT_RS02790	COG4251	negative regulation of phosphorylation
GNIT_RS02790	COG5001	Diguanylate cyclase
GNIT_RS02820	COG2995	paraquat-inducible protein a
GNIT_RS02825	COG3008	intermembrane lipid transfer
GNIT_RS02825	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GNIT_RS02835	COG2239	Acts as a magnesium transporter
GNIT_RS02840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GNIT_RS02845	COG0659	secondary active sulfate transmembrane transporter activity
GNIT_RS02855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GNIT_RS02870	COG2226	methyltransferase
GNIT_RS02880	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GNIT_RS02895	COG0248	Ppx GppA phosphatase
GNIT_RS02900	COG0513	Belongs to the DEAD box helicase family
GNIT_RS02905	COG3118	belongs to the thioredoxin family
GNIT_RS02910	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GNIT_RS02920	COG1473	amidohydrolase
GNIT_RS02925	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GNIT_RS02930	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GNIT_RS02945	COG5001	Diguanylate cyclase
GNIT_RS02970	COG0783	Belongs to the Dps family
GNIT_RS02980	COG3118	belongs to the thioredoxin family
GNIT_RS02990	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GNIT_RS02995	COG1012	belongs to the aldehyde dehydrogenase family
GNIT_RS03005	COG1757	Na H antiporter
GNIT_RS03010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GNIT_RS03025	COG0737	Belongs to the 5'-nucleotidase family
GNIT_RS03035	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GNIT_RS03050	COG2971	BadF BadG BcrA BcrD
GNIT_RS03060	COG2234	aminopeptidase activity
GNIT_RS03070	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GNIT_RS03075	COG0557	exoribonuclease II activity
GNIT_RS03080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GNIT_RS03100	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GNIT_RS03105	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GNIT_RS03110	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GNIT_RS03115	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GNIT_RS03120	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GNIT_RS03125	COG1841	ribosomal large subunit assembly
GNIT_RS03130	COG0200	Binds to the 23S rRNA
GNIT_RS03135	COG0201	protein transport
GNIT_RS03155	COG0202	RNA polymerase activity
GNIT_RS03205	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GNIT_RS03210	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GNIT_RS03210	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GNIT_RS03215	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GNIT_RS03260	COG0583	DNA-binding transcription factor activity
GNIT_RS03280	COG5278	phosphoserine phosphatase activity
GNIT_RS03280	COG0840	transmembrane signaling receptor activity
GNIT_RS03290	COG0318	PFAM AMP-dependent synthetase and ligase
GNIT_RS03300	COG2133	pyrroloquinoline quinone binding
GNIT_RS03315	COG0527	aspartate kinase activity
GNIT_RS03325	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GNIT_RS03330	COG2967	ApaG domain
GNIT_RS03335	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GNIT_RS03340	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GNIT_RS03345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GNIT_RS03350	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GNIT_RS03355	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GNIT_RS03360	COG4974	Belongs to the 'phage' integrase family
GNIT_RS03365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GNIT_RS03370	COG1595	DNA-templated transcription, initiation
GNIT_RS03420	COG0745	RESPONSE REGULATOR receiver
GNIT_RS03425	COG2205	protein histidine kinase activity
GNIT_RS03435	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GNIT_RS03450	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GNIT_RS03455	COG0736	holo-[acyl-carrier-protein] synthase activity
GNIT_RS03465	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GNIT_RS03470	COG3956	TIGRFAM MazG family protein
GNIT_RS03480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GNIT_RS03485	COG0723	plastoquinol--plastocyanin reductase activity
GNIT_RS03490	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GNIT_RS03495	COG2857	Cytochrome c1
GNIT_RS03500	COG0625	glutathione transferase activity
GNIT_RS03505	COG2969	positive regulation of protein catabolic process
GNIT_RS03530	COG0792	nuclease activity
GNIT_RS03535	COG3107	peptidoglycan biosynthetic process
GNIT_RS03540	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GNIT_RS03545	COG1438	arginine binding
GNIT_RS03550	COG0039	L-malate dehydrogenase activity
GNIT_RS03570	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GNIT_RS03575	COG0545	Peptidyl-prolyl cis-trans isomerase
GNIT_RS03585	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GNIT_RS03590	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GNIT_RS03615	COG1442	glycosyl transferase family 8
GNIT_RS03615	COG1216	Glycosyl transferase, family 2
GNIT_RS03620	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GNIT_RS03635	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GNIT_RS03640	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GNIT_RS03650	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GNIT_RS03655	COG1805	sodium ion transport
GNIT_RS03660	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GNIT_RS03665	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GNIT_RS03670	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GNIT_RS03675	COG2871	sodium ion transport
GNIT_RS03680	COG1477	protein flavinylation
GNIT_RS03690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GNIT_RS03695	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GNIT_RS03715	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GNIT_RS03735	COG0702	epimerase
GNIT_RS03750	COG0848	biopolymer transport protein
GNIT_RS03765	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GNIT_RS03765	COG3264	Mechanosensitive ion channel
GNIT_RS03770	COG0716	FMN binding
GNIT_RS03785	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GNIT_RS03800	COG0733	neurotransmitter:sodium symporter activity
GNIT_RS03805	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GNIT_RS03810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GNIT_RS03825	COG0668	transmembrane transport
GNIT_RS03830	COG0204	Acyl-transferase
GNIT_RS03835	COG0204	Acyl-transferase
GNIT_RS03840	COG4251	negative regulation of phosphorylation
GNIT_RS03840	COG5001	Diguanylate cyclase
GNIT_RS03840	COG2203	Gaf domain
GNIT_RS03840	COG3706	GGDEF domain
GNIT_RS03845	COG4251	negative regulation of phosphorylation
GNIT_RS03845	COG5001	Diguanylate cyclase
GNIT_RS03845	COG3706	GGDEF domain
GNIT_RS03845	COG2203	Gaf domain
GNIT_RS03855	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GNIT_RS03865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GNIT_RS03890	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GNIT_RS04010	COG0795	lipopolysaccharide-transporting ATPase activity
GNIT_RS04015	COG0795	lipopolysaccharide-transporting ATPase activity
GNIT_RS04020	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GNIT_RS04025	COG2927	DNA polymerase III (CHI subunit)
GNIT_RS04030	COG0525	valine-tRNA ligase activity
GNIT_RS04040	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GNIT_RS04050	COG2311	Membrane
GNIT_RS04065	COG1295	ribonuclease BN
GNIT_RS04080	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GNIT_RS04100	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
GNIT_RS04110	COG3437	response regulator, receiver
GNIT_RS04115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GNIT_RS04125	COG0739	heme binding
GNIT_RS04130	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GNIT_RS04140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GNIT_RS04145	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GNIT_RS04150	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GNIT_RS04170	COG0493	'glutamate synthase
GNIT_RS04175	COG0067	glutamate synthase
GNIT_RS04175	COG0070	glutamate synthase
GNIT_RS04175	COG0069	glutamate synthase activity
GNIT_RS04180	COG2198	Histidine kinase
GNIT_RS04180	COG0784	Response regulator, receiver
GNIT_RS04180	COG5002	protein histidine kinase activity
GNIT_RS04185	COG1739	Uncharacterized protein family UPF0029
GNIT_RS04190	COG2239	Acts as a magnesium transporter
GNIT_RS04195	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GNIT_RS04200	COG1660	Displays ATPase and GTPase activities
GNIT_RS04205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GNIT_RS04215	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GNIT_RS04220	COG1137	ATPase activity
GNIT_RS04235	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GNIT_RS04240	COG0517	IMP dehydrogenase activity
GNIT_RS04240	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GNIT_RS04250	COG1127	ABC transporter
GNIT_RS04255	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GNIT_RS04260	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GNIT_RS04265	COG2854	intermembrane phospholipid transfer
GNIT_RS04275	COG5007	Belongs to the BolA IbaG family
GNIT_RS04290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GNIT_RS04300	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GNIT_RS04310	COG0784	Response regulator, receiver
GNIT_RS04310	COG2205	protein histidine kinase activity
GNIT_RS04325	COG0653	protein targeting
GNIT_RS04330	COG2264	protein methyltransferase activity
GNIT_RS04350	COG0598	Magnesium transport protein CorA
GNIT_RS04355	COG2194	sulfuric ester hydrolase activity
GNIT_RS04360	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GNIT_RS04370	COG0123	including yeast histone deacetylase and acetoin utilization protein
GNIT_RS04385	COG5001	Diguanylate cyclase
GNIT_RS04385	COG4251	negative regulation of phosphorylation
GNIT_RS04385	COG3706	GGDEF domain
GNIT_RS04385	COG2203	Gaf domain
GNIT_RS04410	COG3706	GGDEF domain
GNIT_RS04430	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GNIT_RS04450	COG0784	Response regulator, receiver
GNIT_RS04450	COG0835	chemotaxis
GNIT_RS04480	COG0745	RESPONSE REGULATOR receiver
GNIT_RS04480	COG3292	Two component regulator propeller
GNIT_RS04480	COG2205	protein histidine kinase activity
GNIT_RS04495	COG0697	spore germination
GNIT_RS04500	COG2207	Transcriptional regulator
GNIT_RS04530	COG1473	amidohydrolase
GNIT_RS04535	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GNIT_RS04540	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GNIT_RS04555	COG0582	viral genome integration into host DNA
GNIT_RS04610	COG1346	cytolysis
GNIT_RS04615	COG2201	protein-glutamate methylesterase activity
GNIT_RS04640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GNIT_RS04645	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GNIT_RS04650	COG0513	Belongs to the DEAD box helicase family
GNIT_RS04655	COG3267	Type II secretory pathway component ExeA
GNIT_RS04655	COG3409	Peptidoglycan-binding domain 1 protein
GNIT_RS04675	COG3437	response regulator, receiver
GNIT_RS04675	COG0784	Response regulator, receiver
GNIT_RS04690	COG0473	3-isopropylmalate dehydrogenase activity
GNIT_RS04695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GNIT_RS04700	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GNIT_RS04715	COG1785	Belongs to the alkaline phosphatase family
GNIT_RS04720	COG0501	Belongs to the peptidase M48B family
GNIT_RS04730	COG0577	efflux transmembrane transporter activity
GNIT_RS04735	COG1136	(ABC) transporter
GNIT_RS04750	COG0754	glutathionylspermidine amidase activity
GNIT_RS04770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GNIT_RS04775	COG1842	Phage shock protein A
GNIT_RS04790	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GNIT_RS04795	COG0343	queuine tRNA-ribosyltransferase activity
GNIT_RS04800	COG1862	Preprotein translocase
GNIT_RS04805	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GNIT_RS04810	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GNIT_RS04815	COG0483	inositol monophosphate 1-phosphatase activity
GNIT_RS04825	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GNIT_RS04830	COG1045	serine acetyltransferase
GNIT_RS04835	COG1959	2 iron, 2 sulfur cluster binding
GNIT_RS04845	COG0105	UTP biosynthetic process
GNIT_RS04850	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GNIT_RS04855	COG3063	Type IV pilus biogenesis stability protein PilW
GNIT_RS04860	COG1426	Protein conserved in bacteria
GNIT_RS04875	COG2976	Protein conserved in bacteria
GNIT_RS04880	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GNIT_RS04895	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GNIT_RS04910	COG1570	exodeoxyribonuclease VII activity
GNIT_RS04915	COG0517	IMP dehydrogenase activity
GNIT_RS04915	COG0516	GMP reductase activity
GNIT_RS04930	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GNIT_RS04940	COG0442	prolyl-tRNA aminoacylation
GNIT_RS04945	COG1720	tRNA m6t6A37 methyltransferase activity
GNIT_RS04990	COG0544	peptidyl-prolyl cis-trans isomerase activity
GNIT_RS04995	COG0740	serine-type endopeptidase activity
GNIT_RS05000	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GNIT_RS05005	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GNIT_RS05010	COG0776	regulation of translation
GNIT_RS05015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GNIT_RS05020	COG0268	Binds directly to 16S ribosomal RNA
GNIT_RS05025	COG0728	peptidoglycan biosynthetic process
GNIT_RS05030	COG0196	riboflavin kinase activity
GNIT_RS05035	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GNIT_RS05045	COG1047	Peptidyl-prolyl cis-trans
GNIT_RS05050	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GNIT_RS05095	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GNIT_RS05100	COG0347	Belongs to the P(II) protein family
GNIT_RS05105	COG1047	Peptidyl-prolyl cis-trans
GNIT_RS05115	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GNIT_RS05130	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GNIT_RS05135	COG1595	DNA-templated transcription, initiation
GNIT_RS05155	COG0481	GTPase activity
GNIT_RS05160	COG0681	Belongs to the peptidase S26 family
GNIT_RS05165	COG0571	ribonuclease III activity
GNIT_RS05170	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GNIT_RS05180	COG0084	hydrolase, TatD family'
GNIT_RS05190	COG0560	Phosphoserine phosphatase
GNIT_RS05200	COG5001	Diguanylate cyclase
GNIT_RS05200	COG5002	protein histidine kinase activity
GNIT_RS05215	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GNIT_RS05225	COG0488	(ABC) transporter
GNIT_RS05230	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GNIT_RS05240	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GNIT_RS05245	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GNIT_RS05245	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GNIT_RS05260	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GNIT_RS05265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GNIT_RS05270	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GNIT_RS05275	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GNIT_RS05280	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GNIT_RS05285	COG0142	geranyltranstransferase activity
GNIT_RS05300	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GNIT_RS05305	COG1360	Flagellar Motor Protein
GNIT_RS05310	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GNIT_RS05320	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GNIT_RS05325	COG4221	oxidoreductase activity
GNIT_RS05340	COG1595	DNA-templated transcription, initiation
GNIT_RS05345	COG3806	Anti-sigma factor
GNIT_RS05355	COG0564	pseudouridine synthase activity
GNIT_RS05360	COG1496	oxidoreductase activity
GNIT_RS05365	COG0542	response to heat
GNIT_RS05375	COG1183	phosphatidylcholine synthase activity
GNIT_RS05420	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GNIT_RS05425	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GNIT_RS05440	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GNIT_RS05445	COG0326	Molecular chaperone. Has ATPase activity
GNIT_RS05485	COG0651	ATP synthesis coupled electron transport
GNIT_RS05495	COG0651	ATP synthesis coupled electron transport
GNIT_RS05500	COG0651	ATP synthesis coupled electron transport
GNIT_RS05505	COG1006	Multisubunit Na H antiporter MnhC subunit
GNIT_RS05515	COG2111	Na H antiporter
GNIT_RS05515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GNIT_RS05525	COG2212	antiporter activity
GNIT_RS05550	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GNIT_RS05550	COG0140	phosphoribosyl-ATP diphosphatase activity
GNIT_RS05560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GNIT_RS05565	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GNIT_RS05570	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GNIT_RS05575	COG0131	Imidazoleglycerol-phosphate dehydratase
GNIT_RS05575	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GNIT_RS05580	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GNIT_RS05585	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GNIT_RS05590	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GNIT_RS05630	COG0471	metal ion transport
GNIT_RS05630	COG3273	potassium ion transport
GNIT_RS05640	COG1218	3'(2'),5'-bisphosphate nucleotidase
GNIT_RS05645	COG0529	Catalyzes the synthesis of activated sulfate
GNIT_RS05650	COG0175	sulfate reduction
GNIT_RS05660	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GNIT_RS05690	COG2304	oxidoreductase activity
GNIT_RS05710	COG0714	Associated with various cellular activities
GNIT_RS05715	COG0183	Belongs to the thiolase family
GNIT_RS05720	COG1024	Enoyl-CoA hydratase
GNIT_RS05720	COG1250	3-hydroxyacyl-CoA dehydrogenase
GNIT_RS05740	COG2062	phosphohistidine phosphatase, SixA
GNIT_RS05750	COG4536	flavin adenine dinucleotide binding
GNIT_RS05755	COG4137	Cytochrome C assembly protein
GNIT_RS05760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GNIT_RS05765	COG0228	four-way junction DNA binding
GNIT_RS05770	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GNIT_RS05775	COG0336	Belongs to the RNA methyltransferase TrmD family
GNIT_RS05780	COG0335	large ribosomal subunit rRNA binding
GNIT_RS05800	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GNIT_RS05805	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GNIT_RS05810	COG0287	Prephenate dehydrogenase
GNIT_RS05810	COG1605	Chorismate mutase
GNIT_RS05815	COG0077	Prephenate dehydratase
GNIT_RS05815	COG1605	Chorismate mutase
GNIT_RS05820	COG0745	RESPONSE REGULATOR receiver
GNIT_RS05825	COG0023	Translation Initiation Factor
GNIT_RS05830	COG1840	ABC-type Fe3 transport system, periplasmic component
GNIT_RS05835	COG1178	ABC-type Fe3 transport system permease component
GNIT_RS05840	COG3842	ATPase activity
GNIT_RS05845	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GNIT_RS05850	COG0494	nUDIX hydrolase
GNIT_RS05855	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GNIT_RS05860	COG0632	four-way junction helicase activity
GNIT_RS05865	COG2255	four-way junction helicase activity
GNIT_RS05870	COG0824	Thioesterase
GNIT_RS05875	COG0811	peptide transport
GNIT_RS05890	COG0823	Involved in the tonB-independent uptake of proteins
GNIT_RS05895	COG2885	chlorophyll binding
GNIT_RS05900	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GNIT_RS05915	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GNIT_RS05945	COG0517	IMP dehydrogenase activity
GNIT_RS05950	COG4974	Belongs to the 'phage' integrase family
GNIT_RS06035	COG0515	serine threonine protein kinase
GNIT_RS06035	COG2815	serine threonine protein kinase
GNIT_RS06055	COG2963	transposase activity
GNIT_RS06085	COG3300	MHYT domain
GNIT_RS06085	COG5001	Diguanylate cyclase
GNIT_RS06100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GNIT_RS06125	COG1022	Amp-dependent synthetase and ligase
GNIT_RS06170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GNIT_RS06175	COG3706	GGDEF domain
GNIT_RS06195	COG1454	alcohol dehydrogenase
GNIT_RS06200	COG1252	NADH dehydrogenase
GNIT_RS06215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GNIT_RS06220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GNIT_RS06225	COG1309	transcriptional regulator
GNIT_RS06230	COG1846	Transcriptional regulator
GNIT_RS06270	COG1136	(ABC) transporter
GNIT_RS06270	COG0577	efflux transmembrane transporter activity
GNIT_RS06300	COG0446	pyridine nucleotide-disulphide oxidoreductase
GNIT_RS06350	COG1522	sequence-specific DNA binding
GNIT_RS06355	COG3706	GGDEF domain
GNIT_RS06360	COG4206	TonB-dependent receptor
GNIT_RS06380	COG0017	Asparaginyl-tRNA synthetase
GNIT_RS06395	COG2205	protein histidine kinase activity
GNIT_RS06405	COG2204	response regulator
GNIT_RS06410	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GNIT_RS06415	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GNIT_RS06420	COG0156	8-amino-7-oxononanoate synthase activity
GNIT_RS06425	COG2226	methyltransferase
GNIT_RS06435	COG3340	Belongs to the peptidase S51 family
GNIT_RS06440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GNIT_RS06445	COG4139	cobalamin transport
GNIT_RS06450	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GNIT_RS06465	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GNIT_RS06470	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
GNIT_RS06475	COG1940	carbohydrate kinase activity
GNIT_RS06495	COG1609	Transcriptional regulator
GNIT_RS06510	COG0702	epimerase
GNIT_RS06515	COG1959	2 iron, 2 sulfur cluster binding
GNIT_RS06520	COG0719	Fe-S assembly protein
GNIT_RS06525	COG0396	ATPase activity
GNIT_RS06530	COG0719	Fe-S assembly protein
GNIT_RS06535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GNIT_RS06550	COG2166	iron-sulfur cluster assembly
GNIT_RS06560	COG3530	Putative quorum-sensing-regulated virulence factor
GNIT_RS06565	COG5265	(ABC) transporter
GNIT_RS06585	COG0511	ligase activity, forming carbon-carbon bonds
GNIT_RS06585	COG5016	pyruvate
GNIT_RS06605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GNIT_RS06625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GNIT_RS06630	COG1228	amidohydrolase
GNIT_RS06635	COG0804	urea catabolic process
GNIT_RS06645	COG3002	Belongs to the UPF0753 family
GNIT_RS06650	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GNIT_RS06655	COG0583	DNA-binding transcription factor activity
GNIT_RS06680	COG4946	Tricorn protease homolog
GNIT_RS06680	COG1506	peptidase
GNIT_RS06680	COG0823	Involved in the tonB-independent uptake of proteins
GNIT_RS06690	COG1476	TRANSCRIPTIONal
GNIT_RS06695	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GNIT_RS06700	COG2755	lipolytic protein G-D-S-L family
GNIT_RS06705	COG4181	ATPase activity
GNIT_RS06710	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GNIT_RS06720	COG3706	GGDEF domain
GNIT_RS06735	COG3123	guanosine phosphorylase activity
GNIT_RS06740	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GNIT_RS06750	COG1090	epimerase
GNIT_RS06755	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GNIT_RS06760	COG0628	permease
GNIT_RS06785	COG3264	Mechanosensitive ion channel
GNIT_RS06785	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GNIT_RS06795	COG2350	Protein conserved in bacteria
GNIT_RS06810	COG0134	indole-3-glycerol-phosphate synthase activity
GNIT_RS06810	COG0135	phosphoribosylanthranilate isomerase activity
GNIT_RS06815	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GNIT_RS06820	COG0512	Glutamine amidotransferase of anthranilate synthase
GNIT_RS06825	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GNIT_RS06830	COG0613	PHP domain protein
GNIT_RS06835	COG0009	L-threonylcarbamoyladenylate synthase
GNIT_RS06845	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GNIT_RS06850	COG1187	pseudouridine synthase activity
GNIT_RS06855	COG0101	tRNA pseudouridine synthase activity
GNIT_RS06860	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GNIT_RS06865	COG0285	dihydrofolate synthase activity
GNIT_RS06870	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GNIT_RS06875	COG1286	toxin biosynthetic process
GNIT_RS06880	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GNIT_RS06885	COG0730	response to heat
GNIT_RS06890	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GNIT_RS06910	COG0110	maltose O-acetyltransferase activity
GNIT_RS06915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GNIT_RS06970	COG1785	Belongs to the alkaline phosphatase family
GNIT_RS06975	COG1785	Belongs to the alkaline phosphatase family
GNIT_RS06980	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GNIT_RS06985	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GNIT_RS06990	COG0215	cysteine-tRNA ligase activity
GNIT_RS06995	COG1388	LysM domain
GNIT_RS06995	COG0741	lytic transglycosylase activity
GNIT_RS07000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GNIT_RS07005	COG2226	methyltransferase
GNIT_RS07025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GNIT_RS07025	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GNIT_RS07030	COG0489	protein tyrosine kinase activity
GNIT_RS07055	COG2205	protein histidine kinase activity
GNIT_RS07055	COG3437	response regulator, receiver
GNIT_RS07055	COG3850	Histidine kinase
GNIT_RS07055	COG4999	Histidine kinase
GNIT_RS07065	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GNIT_RS07090	COG0583	DNA-binding transcription factor activity
GNIT_RS07115	COG0457	Tetratricopeptide repeat
GNIT_RS07130	COG0617	tRNA 3'-terminal CCA addition
GNIT_RS07135	COG0793	Belongs to the peptidase S41A family
GNIT_RS07135	COG4946	Tricorn protease homolog
GNIT_RS07145	COG4807	Protein conserved in bacteria
GNIT_RS07150	COG0488	(ABC) transporter
GNIT_RS07155	COG3264	Mechanosensitive ion channel
GNIT_RS07155	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GNIT_RS07160	COG4555	ABC transporter
GNIT_RS07185	COG0823	Involved in the tonB-independent uptake of proteins
GNIT_RS07185	COG4946	Tricorn protease homolog
GNIT_RS07185	COG1506	peptidase
GNIT_RS07255	COG0746	molybdenum cofactor guanylyltransferase activity
GNIT_RS07270	COG1477	protein flavinylation
GNIT_RS07285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GNIT_RS07325	COG0277	FAD linked oxidase domain protein
GNIT_RS07365	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GNIT_RS07370	COG1074	ATP-dependent DNA helicase activity
GNIT_RS07375	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GNIT_RS07390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GNIT_RS07400	COG1960	acyl-CoA dehydrogenase activity
GNIT_RS07420	COG1028	Short-chain dehydrogenase reductase Sdr
GNIT_RS07425	COG1250	3-hydroxyacyl-CoA dehydrogenase
GNIT_RS07425	COG1024	Enoyl-CoA hydratase
GNIT_RS07430	COG1960	acyl-CoA dehydrogenase activity
GNIT_RS07450	COG4667	esterase of the alpha-beta hydrolase superfamily
GNIT_RS07505	COG0195	Participates in both transcription termination and antitermination
GNIT_RS07510	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GNIT_RS07515	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GNIT_RS07520	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GNIT_RS07525	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GNIT_RS07535	COG3300	MHYT domain
GNIT_RS07535	COG5001	Diguanylate cyclase
GNIT_RS07570	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GNIT_RS07630	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GNIT_RS07655	COG0582	viral genome integration into host DNA
GNIT_RS07660	COG1902	pentaerythritol trinitrate reductase activity
GNIT_RS07670	COG2867	negative regulation of translational initiation
GNIT_RS07675	COG2914	Belongs to the UPF0125 (RnfH) family
GNIT_RS07680	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GNIT_RS07685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GNIT_RS07685	COG0574	Belongs to the PEP-utilizing enzyme family
GNIT_RS07695	COG0277	FAD linked oxidase domain protein
GNIT_RS07695	COG0247	lactate metabolic process
GNIT_RS07705	COG0583	DNA-binding transcription factor activity
GNIT_RS07720	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GNIT_RS07735	COG0714	Associated with various cellular activities
GNIT_RS07740	COG0033	Phosphoglucomutase
GNIT_RS07745	COG0058	SHG alpha-glucan phosphorylase activity
GNIT_RS07750	COG3300	MHYT domain
GNIT_RS07750	COG5001	Diguanylate cyclase
GNIT_RS07755	COG2988	succinylglutamate desuccinylase activity
GNIT_RS07765	COG1876	peptidase activity
GNIT_RS07770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GNIT_RS07775	COG1393	Belongs to the ArsC family
GNIT_RS07790	COG5002	protein histidine kinase activity
GNIT_RS07790	COG5001	Diguanylate cyclase
GNIT_RS07820	COG0004	ammonium transporteR
GNIT_RS07835	COG0840	transmembrane signaling receptor activity
GNIT_RS07840	COG2202	Pas domain
GNIT_RS07840	COG1366	Belongs to the anti-sigma-factor antagonist family
GNIT_RS07850	COG0745	RESPONSE REGULATOR receiver
GNIT_RS07855	COG0643	Histidine kinase
GNIT_RS07855	COG2198	Histidine kinase
GNIT_RS07860	COG0835	chemotaxis
GNIT_RS07865	COG0835	chemotaxis
GNIT_RS07870	COG0840	transmembrane signaling receptor activity
GNIT_RS07875	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GNIT_RS07880	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GNIT_RS07885	COG2201	protein-glutamate methylesterase activity
GNIT_RS07920	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GNIT_RS07935	COG0072	phenylalanine-tRNA ligase activity
GNIT_RS07940	COG0776	regulation of translation
GNIT_RS07955	COG1472	Belongs to the glycosyl hydrolase 3 family
GNIT_RS07960	COG2096	Adenosyltransferase
GNIT_RS07970	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GNIT_RS07980	COG4591	ABC-type transport system involved in lipoprotein release permease component
GNIT_RS08020	COG2814	Major facilitator Superfamily
GNIT_RS08025	COG3239	Fatty acid desaturase
GNIT_RS08030	COG2207	Transcriptional regulator
GNIT_RS08060	COG4770	biotin carboxylase activity
GNIT_RS08065	COG1024	Enoyl-CoA hydratase
GNIT_RS08070	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GNIT_RS08075	COG1960	acyl-CoA dehydrogenase activity
GNIT_RS08080	COG0789	Transcriptional regulator
GNIT_RS08085	COG0183	Belongs to the thiolase family
GNIT_RS08095	COG2925	Exonuclease
GNIT_RS08105	COG1643	Atp-dependent helicase
GNIT_RS08115	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GNIT_RS08120	COG0328	RNA-DNA hybrid ribonuclease activity
GNIT_RS08125	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GNIT_RS08150	COG1136	(ABC) transporter
GNIT_RS08155	COG4591	ABC-type transport system involved in lipoprotein release permease component
GNIT_RS08160	COG1301	dicarboxylic acid transport
GNIT_RS08170	COG3724	N-succinylarginine dihydrolase activity
GNIT_RS08180	COG3122	Protein conserved in bacteria
GNIT_RS08185	COG1530	ribonuclease E activity
GNIT_RS08190	COG0564	pseudouridine synthase activity
GNIT_RS08200	COG0424	maF-like protein
GNIT_RS08205	COG1399	metal-binding, possibly nucleic acid-binding protein
GNIT_RS08215	COG0416	fatty acid biosynthetic process
GNIT_RS08220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GNIT_RS08225	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GNIT_RS08235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GNIT_RS08240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GNIT_RS08250	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GNIT_RS08265	COG0084	hydrolase, TatD family'
GNIT_RS08280	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GNIT_RS08290	COG0436	Aminotransferase
GNIT_RS08305	COG0366	Alpha amylase catalytic
GNIT_RS08345	COG1960	acyl-CoA dehydrogenase activity
GNIT_RS08355	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GNIT_RS08390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GNIT_RS08395	COG4783	chaperone-mediated protein folding
GNIT_RS08405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GNIT_RS08415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GNIT_RS08420	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GNIT_RS08440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GNIT_RS08445	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GNIT_RS08460	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GNIT_RS08465	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GNIT_RS08470	COG0539	negative regulation of cytoplasmic translation
GNIT_RS08475	COG0776	regulation of translation
GNIT_RS08485	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GNIT_RS08490	COG0284	orotidine-5'-phosphate decarboxylase activity
GNIT_RS08495	COG0686	Belongs to the AlaDH PNT family
GNIT_RS08505	COG1674	ftsk spoiiie
GNIT_RS08505	COG0531	amino acid
GNIT_RS08515	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GNIT_RS08520	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GNIT_RS08530	COG2920	part of a sulfur-relay system
GNIT_RS08545	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GNIT_RS08550	COG0670	Belongs to the BI1 family
GNIT_RS08560	COG2197	response regulator
GNIT_RS08565	COG0322	excinuclease ABC activity
GNIT_RS08585	COG0582	viral genome integration into host DNA
GNIT_RS08605	COG0330	HflC and HflK could
GNIT_RS08615	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
GNIT_RS08660	COG1280	lysine exporter protein (LysE YggA)
GNIT_RS08680	COG1752	Esterase of the alpha-beta hydrolase superfamily
GNIT_RS08690	COG0589	response to stress
GNIT_RS08695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GNIT_RS08710	COG2217	Heavy metal translocating P-type atpase
GNIT_RS08720	COG2010	Cytochrome c
GNIT_RS08735	COG3278	Belongs to the heme-copper respiratory oxidase family
GNIT_RS08745	COG2193	ferroxidase activity
GNIT_RS08760	COG0596	Alpha beta hydrolase
GNIT_RS08785	COG1160	GTP binding
GNIT_RS08790	COG0659	secondary active sulfate transmembrane transporter activity
GNIT_RS08795	COG0205	6-phosphofructokinase activity
GNIT_RS08865	COG2165	general secretion pathway protein
GNIT_RS08880	COG2084	Dehydrogenase
GNIT_RS08895	COG3046	protein related to deoxyribodipyrimidine photolyase
GNIT_RS08900	COG0415	Belongs to the DNA photolyase family
GNIT_RS08905	COG0415	Belongs to the DNA photolyase family
GNIT_RS08910	COG0415	Belongs to the DNA photolyase family
GNIT_RS08920	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GNIT_RS08930	COG0488	(ABC) transporter
GNIT_RS08940	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GNIT_RS08940	COG0116	Belongs to the methyltransferase superfamily
GNIT_RS08945	COG0167	dihydroorotate dehydrogenase activity
GNIT_RS08950	COG2902	Dehydrogenase
GNIT_RS08975	COG0308	aminopeptidase N
GNIT_RS08980	COG1757	Na H antiporter
GNIT_RS08985	COG0733	neurotransmitter:sodium symporter activity
GNIT_RS08990	COG0793	Belongs to the peptidase S41A family
GNIT_RS09005	COG1956	GAF domain-containing protein
GNIT_RS09010	COG2715	membrane protein required for spore maturation
GNIT_RS09020	COG1946	Acyl-CoA thioesterase
GNIT_RS09025	COG0515	serine threonine protein kinase
GNIT_RS09030	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GNIT_RS09040	COG0022	dehydrogenase e1 component
GNIT_RS09050	COG0534	Mate efflux family protein
GNIT_RS09055	COG1187	pseudouridine synthase activity
GNIT_RS09080	COG0405	Gamma-glutamyltransferase
GNIT_RS09085	COG1024	Enoyl-CoA hydratase
GNIT_RS09110	COG2873	o-acetylhomoserine
GNIT_RS09120	COG1448	Aminotransferase
GNIT_RS09125	COG1671	Belongs to the UPF0178 family
GNIT_RS09130	COG1028	Short-chain dehydrogenase reductase Sdr
GNIT_RS09135	COG1028	Short-chain dehydrogenase reductase Sdr
GNIT_RS09140	COG2130	NADP-dependent
GNIT_RS09145	COG1960	acyl-CoA dehydrogenase activity
GNIT_RS09155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GNIT_RS09170	COG0314	molybdopterin synthase activity
GNIT_RS09190	COG0596	Alpha beta hydrolase
GNIT_RS09235	COG0735	belongs to the Fur family
GNIT_RS09245	COG1984	allophanate hydrolase subunit 2
GNIT_RS09250	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GNIT_RS09255	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GNIT_RS09265	COG1765	OsmC-like protein
GNIT_RS09275	COG1322	Protein conserved in bacteria
GNIT_RS09295	COG1760	l-serine dehydratase
GNIT_RS09300	COG0583	DNA-binding transcription factor activity
GNIT_RS09315	COG0583	DNA-binding transcription factor activity
GNIT_RS09320	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GNIT_RS09325	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GNIT_RS09330	COG0513	Belongs to the DEAD box helicase family
GNIT_RS09335	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GNIT_RS09345	COG1054	Belongs to the UPF0176 family
GNIT_RS09365	COG0697	spore germination
GNIT_RS09420	COG1796	DNA polymerase
GNIT_RS09420	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GNIT_RS09425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GNIT_RS09430	COG0516	GMP reductase activity
GNIT_RS09430	COG0517	IMP dehydrogenase activity
GNIT_RS09465	COG3081	Nucleoid-associated protein
GNIT_RS09470	COG3082	Protein of unknown function (DUF1414)
GNIT_RS09490	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GNIT_RS09495	COG2226	methyltransferase
GNIT_RS09505	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GNIT_RS09510	COG1960	acyl-CoA dehydrogenase activity
GNIT_RS09525	COG0386	Belongs to the glutathione peroxidase family
GNIT_RS09530	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GNIT_RS09535	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GNIT_RS09545	COG0616	signal peptide processing
GNIT_RS09555	COG2267	carboxylic ester hydrolase activity
GNIT_RS09560	COG1028	Short-chain dehydrogenase reductase Sdr
GNIT_RS09580	COG0477	Major facilitator Superfamily
GNIT_RS09590	COG1501	Belongs to the glycosyl hydrolase 31 family
GNIT_RS09595	COG0366	Alpha amylase catalytic
GNIT_RS09605	COG2192	nodulation
GNIT_RS09625	COG0659	secondary active sulfate transmembrane transporter activity
GNIT_RS09650	COG0508	dehydrogenase complex catalyzes the overall conversion of
GNIT_RS09655	COG0567	Dehydrogenase, E1 component
GNIT_RS09660	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GNIT_RS09665	COG1053	succinate dehydrogenase
GNIT_RS09670	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GNIT_RS09705	COG0435	Glutathione S-transferase
GNIT_RS09710	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GNIT_RS09750	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GNIT_RS09755	COG2835	tetraacyldisaccharide 4'-kinase activity
GNIT_RS09760	COG1663	tetraacyldisaccharide 4'-kinase activity
GNIT_RS09765	COG1132	(ABC) transporter
GNIT_RS09770	COG0658	competence protein
GNIT_RS09770	COG2333	competence protein COMEC
GNIT_RS09780	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GNIT_RS09790	COG1196	nuclear chromosome segregation
GNIT_RS09815	COG1185	polyribonucleotide nucleotidyltransferase activity
GNIT_RS09820	COG0583	DNA-binding transcription factor activity
GNIT_RS09840	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GNIT_RS09845	COG0149	triose-phosphate isomerase activity
GNIT_RS09850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GNIT_RS09855	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GNIT_RS09865	COG1534	Rna-binding protein
GNIT_RS09875	COG1067	ATP-dependent peptidase activity
GNIT_RS09880	COG0495	leucyl-tRNA aminoacylation
GNIT_RS09885	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GNIT_RS09890	COG1466	dna polymerase III delta subunit
GNIT_RS09895	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GNIT_RS09900	COG0799	negative regulation of ribosome biogenesis
GNIT_RS09905	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GNIT_RS09910	COG0768	penicillin binding
GNIT_RS09915	COG0772	Belongs to the SEDS family
GNIT_RS09920	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GNIT_RS09925	COG1686	Belongs to the peptidase S11 family
GNIT_RS09930	COG2921	Belongs to the UPF0250 family
GNIT_RS09935	COG0321	lipoyl(octanoyl) transferase activity
GNIT_RS09940	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GNIT_RS09950	COG0626	cystathionine gamma-synthase activity
GNIT_RS09955	COG0252	asparaginase activity
GNIT_RS09965	COG3139	Protein of unknown function (DUF1315)
GNIT_RS09975	COG1115	amino acid carrier protein
GNIT_RS09980	COG2866	Carboxypeptidase
GNIT_RS10005	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GNIT_RS10015	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GNIT_RS10020	COG1640	4-alpha-glucanotransferase
GNIT_RS10030	COG0676	glucose-6-phosphate 1-epimerase activity
GNIT_RS10035	COG0800	Aldolase
GNIT_RS10045	COG0129	dihydroxy-acid dehydratase activity
GNIT_RS10050	COG0363	glucosamine-6-phosphate deaminase activity
GNIT_RS10055	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GNIT_RS10060	COG1737	Transcriptional regulator
GNIT_RS10065	COG0469	pyruvate kinase activity
GNIT_RS10070	COG3268	Saccharopine dehydrogenase
GNIT_RS10075	COG0778	Nitroreductase
GNIT_RS10080	COG0616	signal peptide processing
GNIT_RS10085	COG3091	SprT-like family
GNIT_RS10090	COG3092	negative regulation of chromosome organization
GNIT_RS10095	COG0492	ferredoxin-NADP+ reductase activity
GNIT_RS10100	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GNIT_RS10105	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GNIT_RS10110	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GNIT_RS10115	COG0542	response to heat
GNIT_RS10120	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GNIT_RS10125	COG1278	Cold shock
GNIT_RS10130	COG1187	pseudouridine synthase activity
GNIT_RS10135	COG0482	sulfurtransferase activity
GNIT_RS10145	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GNIT_RS10155	COG2850	peptidyl-arginine hydroxylation
GNIT_RS10165	COG3012	SEC-C Motif Domain Protein
GNIT_RS10175	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GNIT_RS10185	COG2890	protein-(glutamine-N5) methyltransferase activity
GNIT_RS10195	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GNIT_RS10200	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GNIT_RS10205	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GNIT_RS10215	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GNIT_RS10225	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GNIT_RS10270	COG1115	amino acid carrier protein
GNIT_RS10275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GNIT_RS10285	COG1702	phosphate starvation-inducible protein PhoH
GNIT_RS10290	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GNIT_RS10295	COG4535	Mg2 and Co2 transporter CorC
GNIT_RS10305	COG0659	secondary active sulfate transmembrane transporter activity
GNIT_RS10310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GNIT_RS10315	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GNIT_RS10320	COG0505	Belongs to the CarA family
GNIT_RS10330	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GNIT_RS10345	COG0484	heat shock protein binding
GNIT_RS10355	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GNIT_RS10360	COG2205	protein histidine kinase activity
GNIT_RS10390	COG2610	gluconate transmembrane transporter activity
GNIT_RS10395	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GNIT_RS10405	COG1028	Short-chain dehydrogenase reductase Sdr
GNIT_RS10410	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GNIT_RS10415	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GNIT_RS10420	COG2814	Major facilitator Superfamily
GNIT_RS10425	COG1320	monovalent cation:proton antiporter activity
GNIT_RS10430	COG2212	antiporter activity
GNIT_RS10435	COG1863	multisubunit Na H antiporter MnhE subunit
GNIT_RS10440	COG0651	ATP synthesis coupled electron transport
GNIT_RS10445	COG1006	Multisubunit Na H antiporter MnhC subunit
GNIT_RS10450	COG2111	Na H antiporter
GNIT_RS10450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GNIT_RS10460	COG0497	DNA recombination
GNIT_RS10465	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GNIT_RS10470	COG3706	GGDEF domain
GNIT_RS10485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GNIT_RS10490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GNIT_RS10495	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GNIT_RS10495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GNIT_RS10510	COG3101	peptidyl-lysine hydroxylation
GNIT_RS10525	COG1902	pentaerythritol trinitrate reductase activity
GNIT_RS10525	COG0446	pyridine nucleotide-disulphide oxidoreductase
GNIT_RS10545	COG1278	Cold shock
GNIT_RS10555	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GNIT_RS10560	COG2983	Belongs to the UPF0260 family
GNIT_RS10565	COG0179	Fumarylacetoacetate (FAA) hydrolase
GNIT_RS10570	COG2951	lytic endotransglycosylase activity
GNIT_RS10575	COG3100	YcgL domain-containing protein
GNIT_RS10580	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GNIT_RS10585	COG0318	PFAM AMP-dependent synthetase and ligase
GNIT_RS10590	COG2267	carboxylic ester hydrolase activity
GNIT_RS10605	COG1214	PFAM Peptidase M22, glycoprotease
GNIT_RS10610	COG1199	ATP-dependent helicase activity
GNIT_RS10615	COG1668	transmembrane transport
GNIT_RS10620	COG4555	ABC transporter
GNIT_RS10640	COG0367	asparagine synthase
GNIT_RS10650	COG0602	queuosine metabolic process
GNIT_RS10655	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GNIT_RS10665	COG0556	nucleotide-excision repair
GNIT_RS10670	COG0534	Mate efflux family protein
GNIT_RS10685	COG4657	Part of a membrane complex involved in electron transport
GNIT_RS10690	COG2878	Part of a membrane complex involved in electron transport
GNIT_RS10700	COG4658	electron transport chain
GNIT_RS10705	COG4659	FMN binding
GNIT_RS10710	COG4660	Part of a membrane complex involved in electron transport
GNIT_RS10715	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GNIT_RS10780	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GNIT_RS10785	COG0346	lactoylglutathione lyase activity
GNIT_RS10790	COG0584	glycerophosphoryl diester phosphodiesterase
GNIT_RS10795	COG2885	chlorophyll binding
GNIT_RS10810	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GNIT_RS10815	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GNIT_RS10830	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GNIT_RS10840	COG2840	Smr protein MutS2
GNIT_RS10850	COG2918	glutathione biosynthetic process
GNIT_RS10855	COG0612	Peptidase, M16
GNIT_RS10865	COG0564	pseudouridine synthase activity
GNIT_RS10870	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GNIT_RS10875	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GNIT_RS10880	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GNIT_RS10885	COG0431	NADPH-dependent FMN reductase
GNIT_RS10895	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GNIT_RS10900	COG0456	acetyltransferase
GNIT_RS10940	COG1444	tRNA N-acetyltransferase activity
GNIT_RS10955	COG0848	biopolymer transport protein
GNIT_RS10960	COG0811	peptide transport
GNIT_RS10965	COG0811	peptide transport
GNIT_RS10980	COG4206	TonB-dependent receptor
GNIT_RS10995	COG1522	sequence-specific DNA binding
GNIT_RS11000	COG0625	glutathione transferase activity
GNIT_RS11020	COG1983	PspC domain protein
GNIT_RS11030	COG1842	Phage shock protein A
GNIT_RS11035	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GNIT_RS11040	COG0747	negative chemotaxis
GNIT_RS11045	COG0601	transmembrane transport
GNIT_RS11050	COG4171	peptide transport system, permease
GNIT_RS11055	COG4172	Belongs to the ABC transporter superfamily
GNIT_RS11060	COG4172	Belongs to the ABC transporter superfamily
GNIT_RS11065	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GNIT_RS11075	COG3630	sodium ion export across plasma membrane
GNIT_RS11095	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GNIT_RS11100	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GNIT_RS11115	COG3590	peptidase
GNIT_RS11125	COG1410	methionine synthase
GNIT_RS11125	COG0646	methionine synthase
GNIT_RS11130	COG1410	methionine synthase
GNIT_RS11130	COG0646	methionine synthase
GNIT_RS11145	COG0835	chemotaxis
GNIT_RS11155	COG1192	Involved in chromosome partitioning
GNIT_RS11160	COG2201	protein-glutamate methylesterase activity
GNIT_RS11165	COG0784	Response regulator, receiver
GNIT_RS11165	COG2198	Histidine kinase
GNIT_RS11165	COG0643	Histidine kinase
GNIT_RS11170	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GNIT_RS11205	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GNIT_RS11210	COG1684	flagellar biosynthetic protein fliR
GNIT_RS11215	COG1987	bacterial-type flagellum assembly
GNIT_RS11265	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GNIT_RS11270	COG1766	The M ring may be actively involved in energy transduction
GNIT_RS11275	COG1677	Flagellar hook-basal body complex protein FliE
GNIT_RS11310	COG1028	Short-chain dehydrogenase reductase Sdr
GNIT_RS11315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GNIT_RS11335	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GNIT_RS11350	COG0463	Glycosyl transferase, family 2
GNIT_RS11365	COG1028	Short-chain dehydrogenase reductase Sdr
GNIT_RS11385	COG2089	acid synthase
GNIT_RS11395	COG1083	cytidylyl-transferase
GNIT_RS11400	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GNIT_RS11405	COG1086	Polysaccharide biosynthesis protein
GNIT_RS11445	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GNIT_RS11470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GNIT_RS11480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GNIT_RS11490	COG3951	Flagellar rod assembly protein muramidase FlgJ
GNIT_RS11490	COG1705	Flagellar rod assembly protein muramidase FlgJ
GNIT_RS11495	COG1706	bacterial-type flagellum-dependent cell motility
GNIT_RS11510	COG4787	bacterial-type flagellum-dependent cell motility
GNIT_RS11515	COG1749	Flagellar hook protein flgE
GNIT_RS11520	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GNIT_RS11530	COG1815	bacterial-type flagellum-dependent cell motility
GNIT_RS11535	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GNIT_RS11540	COG0835	chemotaxis
GNIT_RS11540	COG0784	Response regulator, receiver
GNIT_RS11575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GNIT_RS11575	COG0047	phosphoribosylformylglycinamidine synthase activity
GNIT_RS11590	COG0590	tRNA wobble adenosine to inosine editing
GNIT_RS11605	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GNIT_RS11625	COG0825	malonyl-CoA metabolic process
GNIT_RS11630	COG0587	DNA-directed DNA polymerase activity
GNIT_RS11635	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GNIT_RS11645	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GNIT_RS11650	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GNIT_RS11655	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GNIT_RS11665	COG0750	zinc metalloprotease
GNIT_RS11670	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GNIT_RS11675	COG0575	Belongs to the CDS family
GNIT_RS11680	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GNIT_RS11690	COG0528	UMP kinase activity
GNIT_RS11705	COG0052	Belongs to the universal ribosomal protein uS2 family
GNIT_RS11710	COG1902	pentaerythritol trinitrate reductase activity
GNIT_RS11715	COG0024	Methionine aminopeptidase
GNIT_RS11720	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GNIT_RS11735	COG0471	metal ion transport
GNIT_RS11740	COG0564	pseudouridine synthase activity
GNIT_RS11775	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GNIT_RS11775	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GNIT_RS11785	COG1611	Belongs to the LOG family
GNIT_RS11790	COG0473	3-isopropylmalate dehydrogenase activity
GNIT_RS11800	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GNIT_RS11840	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GNIT_RS11855	COG4235	cytochrome complex assembly
GNIT_RS11855	COG3088	subunit of a heme lyase
GNIT_RS11860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GNIT_RS11865	COG1138	Cytochrome C-type biogenesis protein
GNIT_RS11875	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GNIT_RS11880	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GNIT_RS11885	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GNIT_RS11890	COG4133	protoheme IX ABC transporter activity
GNIT_RS11905	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GNIT_RS11910	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GNIT_RS11915	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GNIT_RS11930	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GNIT_RS11940	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GNIT_RS11945	COG0504	CTP synthase activity
GNIT_RS11960	COG1858	cytochrome C peroxidase
GNIT_RS11975	COG1132	(ABC) transporter
GNIT_RS12015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GNIT_RS12050	COG3328	transposase activity
GNIT_RS12055	COG1088	dTDP-glucose 4,6-dehydratase activity
GNIT_RS12060	COG1091	dTDP-4-dehydrorhamnose reductase activity
GNIT_RS12080	COG1215	transferase activity, transferring glycosyl groups
GNIT_RS12090	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GNIT_RS12160	COG0438	transferase activity, transferring glycosyl groups
GNIT_RS12170	COG0367	asparagine synthase
GNIT_RS12175	COG0438	transferase activity, transferring glycosyl groups
GNIT_RS12200	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GNIT_RS12215	COG3206	protein involved in exopolysaccharide biosynthesis
GNIT_RS12215	COG0489	protein tyrosine kinase activity
GNIT_RS12225	COG3409	Peptidoglycan-binding domain 1 protein
GNIT_RS12225	COG3267	Type II secretory pathway component ExeA
GNIT_RS12230	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GNIT_RS12230	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GNIT_RS12255	COG1560	Kdo2-lipid A biosynthetic process
GNIT_RS12265	COG1960	acyl-CoA dehydrogenase activity
GNIT_RS12320	COG3220	belongs to the UPF0276 family
GNIT_RS12360	COG0432	Pfam Uncharacterised protein family UPF0047
GNIT_RS12435	COG0477	Major facilitator Superfamily
GNIT_RS12460	COG1032	radical SAM domain protein
GNIT_RS12465	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GNIT_RS12480	COG2116	formate transmembrane transporter activity
GNIT_RS12500	COG4771	TonB-dependent receptor
GNIT_RS12505	COG4221	oxidoreductase activity
GNIT_RS12510	COG0667	Aldo Keto reductase
GNIT_RS12525	COG3706	GGDEF domain
GNIT_RS12565	COG0604	alcohol dehydrogenase
GNIT_RS12570	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GNIT_RS12570	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GNIT_RS12585	COG0583	DNA-binding transcription factor activity
GNIT_RS12600	COG1228	amidohydrolase
GNIT_RS12625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GNIT_RS12630	COG0006	proline dipeptidase activity
GNIT_RS12635	COG3079	Belongs to the UPF0149 family
GNIT_RS12640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GNIT_RS12650	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GNIT_RS12655	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GNIT_RS12660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GNIT_RS12670	COG3137	Salt-induced outer membrane protein
GNIT_RS12685	COG3313	Fe-S protein
GNIT_RS12690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GNIT_RS12695	COG0508	dehydrogenase complex catalyzes the overall conversion of
GNIT_RS12700	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GNIT_RS12710	COG3725	Membrane protein required for beta-lactamase induction
GNIT_RS12720	COG4969	Belongs to the N-Me-Phe pilin family
GNIT_RS12725	COG1459	type II secretion system
GNIT_RS12735	COG0237	dephospho-CoA kinase activity
GNIT_RS12740	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GNIT_RS12745	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GNIT_RS12750	COG2988	succinylglutamate desuccinylase activity
GNIT_RS12755	COG1309	transcriptional regulator
GNIT_RS12770	COG0494	nUDIX hydrolase
GNIT_RS12780	COG0739	heme binding
GNIT_RS12785	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GNIT_RS12795	COG0849	cell division
GNIT_RS12800	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GNIT_RS12805	COG1181	Belongs to the D-alanine--D-alanine ligase family
GNIT_RS12810	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GNIT_RS12815	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GNIT_RS12820	COG0772	Belongs to the SEDS family
GNIT_RS12825	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GNIT_RS12835	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GNIT_RS12840	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GNIT_RS12845	COG0768	penicillin binding
GNIT_RS12850	COG3116	cell division
GNIT_RS12860	COG2001	Belongs to the MraZ family
GNIT_RS12875	COG0724	RNA recognition motif
GNIT_RS12890	COG0678	peroxiredoxin activity
GNIT_RS12890	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GNIT_RS12900	COG2204	response regulator
GNIT_RS12905	COG5002	protein histidine kinase activity
GNIT_RS12925	COG0306	phosphate transporter
GNIT_RS12935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GNIT_RS12945	COG0573	inorganic phosphate transmembrane transporter activity
GNIT_RS12955	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GNIT_RS12965	COG3588	fructose-bisphosphate aldolase
GNIT_RS12970	COG0126	phosphoglycerate kinase activity
GNIT_RS12975	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GNIT_RS12980	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GNIT_RS12985	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GNIT_RS12995	COG0668	transmembrane transport
GNIT_RS13005	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GNIT_RS13010	COG0189	ligase activity
GNIT_RS13015	COG1678	Uncharacterized ACR, COG1678
GNIT_RS13020	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GNIT_RS13025	COG5001	Diguanylate cyclase
GNIT_RS13025	COG2203	Gaf domain
GNIT_RS13025	COG4251	negative regulation of phosphorylation
GNIT_RS13025	COG3706	GGDEF domain
GNIT_RS13050	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GNIT_RS13055	COG0762	integral membrane protein
GNIT_RS13075	COG0166	Belongs to the GPI family
GNIT_RS13090	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GNIT_RS13120	COG0513	Belongs to the DEAD box helicase family
GNIT_RS13130	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
GNIT_RS13140	COG0745	RESPONSE REGULATOR receiver
GNIT_RS13170	COG1748	Saccharopine dehydrogenase
GNIT_RS13190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GNIT_RS13210	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GNIT_RS13210	COG0517	IMP dehydrogenase activity
GNIT_RS13215	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GNIT_RS13250	COG1793	dna ligase
GNIT_RS13255	COG2205	protein histidine kinase activity
GNIT_RS13255	COG0784	Response regulator, receiver
GNIT_RS13265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GNIT_RS13280	COG0667	Aldo Keto reductase
GNIT_RS13285	COG0123	including yeast histone deacetylase and acetoin utilization protein
GNIT_RS13290	COG0427	acetyl-CoA hydrolase
GNIT_RS13295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GNIT_RS13325	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GNIT_RS13330	COG0848	biopolymer transport protein
GNIT_RS13335	COG0811	peptide transport
GNIT_RS13340	COG0811	peptide transport
GNIT_RS13365	COG5002	protein histidine kinase activity
GNIT_RS13370	COG0745	RESPONSE REGULATOR receiver
GNIT_RS13375	COG2974	May be involved in recombination
GNIT_RS13390	COG0537	adenosine 5'-monophosphoramidase activity
GNIT_RS13410	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GNIT_RS13430	COG0358	DNA primase activity
GNIT_RS13440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GNIT_RS13455	COG1960	acyl-CoA dehydrogenase activity
GNIT_RS13480	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GNIT_RS13495	COG0348	domain, Protein
GNIT_RS13500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GNIT_RS13510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GNIT_RS13515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GNIT_RS13525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GNIT_RS13530	COG0659	secondary active sulfate transmembrane transporter activity
GNIT_RS13535	COG0271	Belongs to the BolA IbaG family
GNIT_RS13545	COG2813	Specifically methylates the guanine in position
GNIT_RS13560	COG1012	belongs to the aldehyde dehydrogenase family
GNIT_RS13565	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GNIT_RS13570	COG1187	pseudouridine synthase activity
GNIT_RS13575	COG0450	alkyl hydroperoxide reductase
GNIT_RS13600	COG3383	formate dehydrogenase (NAD+) activity
GNIT_RS13605	COG0653	protein targeting
GNIT_RS13610	COG2116	formate transmembrane transporter activity
GNIT_RS13620	COG0508	dehydrogenase complex catalyzes the overall conversion of
GNIT_RS13625	COG0022	dehydrogenase e1 component
GNIT_RS13625	COG0508	dehydrogenase complex catalyzes the overall conversion of
GNIT_RS13630	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GNIT_RS13635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GNIT_RS13655	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GNIT_RS13660	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GNIT_RS13665	COG1509	lysine 2,3-aminomutase activity
GNIT_RS13695	COG3150	esterase
GNIT_RS13700	COG3151	Protein conserved in bacteria
GNIT_RS13705	COG0494	nUDIX hydrolase
GNIT_RS13710	COG1538	Outer membrane efflux protein
GNIT_RS13725	COG0513	Belongs to the DEAD box helicase family
GNIT_RS13730	COG1648	precorrin-2 dehydrogenase activity
GNIT_RS13730	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GNIT_RS13755	COG2197	response regulator
GNIT_RS13760	COG2911	Protein conserved in bacteria
GNIT_RS13765	COG2911	Protein conserved in bacteria
GNIT_RS13770	COG0729	surface antigen
GNIT_RS13785	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GNIT_RS13790	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GNIT_RS13795	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GNIT_RS13805	COG0281	malic enzyme
GNIT_RS13810	COG3634	alkyl hydroperoxide reductase activity
GNIT_RS13815	COG0450	alkyl hydroperoxide reductase
GNIT_RS13820	COG3025	triphosphatase activity
GNIT_RS13825	COG4991	sh3 domain protein
GNIT_RS13835	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GNIT_RS13835	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GNIT_RS13835	COG0506	proline dehydrogenase activity
GNIT_RS13845	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GNIT_RS13850	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GNIT_RS13860	COG0585	pseudouridine synthase activity
GNIT_RS13865	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GNIT_RS13870	COG1238	metal cluster binding
GNIT_RS13895	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GNIT_RS13915	COG0142	geranyltranstransferase activity
GNIT_RS13920	COG0006	proline dipeptidase activity
GNIT_RS13930	COG1250	3-hydroxyacyl-CoA dehydrogenase
GNIT_RS13930	COG1024	Enoyl-CoA hydratase
GNIT_RS13935	COG0183	Belongs to the thiolase family
GNIT_RS13945	COG0564	pseudouridine synthase activity
GNIT_RS13955	COG1451	nucleotide metabolic process
GNIT_RS13965	COG3706	GGDEF domain
GNIT_RS13980	COG3383	formate dehydrogenase (NAD+) activity
GNIT_RS13985	COG0513	Belongs to the DEAD box helicase family
GNIT_RS14045	COG1136	(ABC) transporter
GNIT_RS14060	COG0612	Peptidase, M16
GNIT_RS14065	COG2873	o-acetylhomoserine
GNIT_RS14075	COG1278	Cold shock
GNIT_RS14085	COG0028	Belongs to the TPP enzyme family
GNIT_RS14105	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GNIT_RS14110	COG1162	GTPase activity
GNIT_RS14140	COG2861	carbohydrate metabolic process
GNIT_RS14175	COG0076	glutamate decarboxylase activity
GNIT_RS14180	COG2200	EAL domain
GNIT_RS14185	COG4106	trans-aconitate 2-methyltransferase activity
GNIT_RS14190	COG0842	Transport permease protein
GNIT_RS14195	COG1131	(ABC) transporter
GNIT_RS14210	COG1253	flavin adenine dinucleotide binding
GNIT_RS14230	COG5001	Diguanylate cyclase
GNIT_RS14230	COG3300	MHYT domain
GNIT_RS14235	COG0596	Alpha beta hydrolase
GNIT_RS14245	COG1757	Na H antiporter
GNIT_RS14255	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GNIT_RS14265	COG0513	Belongs to the DEAD box helicase family
GNIT_RS14285	COG0714	Associated with various cellular activities
GNIT_RS14360	COG1272	protein, Hemolysin III
GNIT_RS14365	COG1643	Atp-dependent helicase
GNIT_RS14380	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GNIT_RS14385	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GNIT_RS14385	COG0189	ligase activity
GNIT_RS14390	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GNIT_RS14390	COG0189	ligase activity
GNIT_RS14400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GNIT_RS14425	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GNIT_RS14430	COG0049	tRNA binding
GNIT_RS14435	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GNIT_RS14440	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GNIT_RS14445	COG0085	RNA polymerase activity
GNIT_RS14450	COG0222	ribosome binding
GNIT_RS14455	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GNIT_RS14460	COG0081	regulation of translation
GNIT_RS14465	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GNIT_RS14470	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GNIT_RS14475	COG0250	Participates in transcription elongation, termination and antitermination
GNIT_RS14480	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GNIT_RS14490	COG1132	(ABC) transporter
GNIT_RS14500	COG3590	peptidase
GNIT_RS14505	COG0534	Mate efflux family protein
GNIT_RS14530	COG0513	Belongs to the DEAD box helicase family
GNIT_RS14535	COG0418	dihydroorotase activity
GNIT_RS14560	COG4989	oxidoreductase activity
GNIT_RS14575	COG0302	gtp cyclohydrolase
GNIT_RS14590	COG2957	Belongs to the agmatine deiminase family
GNIT_RS14595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GNIT_RS14605	COG1201	RNA secondary structure unwinding
GNIT_RS14615	COG1793	dna ligase
GNIT_RS14635	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GNIT_RS14660	COG1091	dTDP-4-dehydrorhamnose reductase activity
GNIT_RS14680	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GNIT_RS14765	COG1450	Type ii and iii secretion system protein
GNIT_RS14790	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GNIT_RS14805	COG0438	transferase activity, transferring glycosyl groups
GNIT_RS14805	COG1216	Glycosyl transferase, family 2
GNIT_RS14840	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GNIT_RS14855	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GNIT_RS14860	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GNIT_RS14875	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GNIT_RS14885	COG0330	HflC and HflK could
GNIT_RS14890	COG0330	HflC and HflK could
GNIT_RS14895	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GNIT_RS14900	COG1923	regulation of RNA biosynthetic process
GNIT_RS14905	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GNIT_RS14920	COG0802	atpase or kinase
GNIT_RS14925	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GNIT_RS14925	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GNIT_RS14935	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GNIT_RS14945	COG0735	belongs to the Fur family
GNIT_RS14960	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GNIT_RS14965	COG0372	Belongs to the citrate synthase family
GNIT_RS14970	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GNIT_RS14975	COG2828	Protein conserved in bacteria
GNIT_RS14980	COG0625	glutathione transferase activity
GNIT_RS14995	COG1404	Belongs to the peptidase S8 family
GNIT_RS15005	COG2059	Chromate
GNIT_RS15035	COG2258	MOSC domain
GNIT_RS15040	COG0183	Belongs to the thiolase family
GNIT_RS15055	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GNIT_RS15075	COG2204	response regulator
GNIT_RS15080	COG4771	TonB-dependent receptor
GNIT_RS15085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GNIT_RS15100	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
GNIT_RS15105	COG1335	isochorismatase
GNIT_RS15120	COG1028	Short-chain dehydrogenase reductase Sdr
GNIT_RS15125	COG2311	Membrane
GNIT_RS15155	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GNIT_RS15160	COG2813	Specifically methylates the guanine in position
GNIT_RS15165	COG0297	glycogen (starch) synthase activity
GNIT_RS15170	COG0745	RESPONSE REGULATOR receiver
GNIT_RS15175	COG0312	modulator of DNA gyrase
GNIT_RS15180	COG3028	Belongs to the UPF0307 family
GNIT_RS15240	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GNIT_RS15315	COG2211	Major facilitator Superfamily
GNIT_RS15345	COG0534	Mate efflux family protein
GNIT_RS15355	COG3275	phosphorelay sensor kinase activity
GNIT_RS15360	COG3279	Response regulator of the LytR AlgR family
GNIT_RS15370	COG5001	Diguanylate cyclase
GNIT_RS15370	COG5002	protein histidine kinase activity
GNIT_RS15380	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GNIT_RS15395	COG5001	Diguanylate cyclase
GNIT_RS15410	COG0604	alcohol dehydrogenase
GNIT_RS15415	COG1979	alcohol dehydrogenase
GNIT_RS15425	COG0583	DNA-binding transcription factor activity
GNIT_RS15430	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GNIT_RS15435	COG1228	amidohydrolase
GNIT_RS15450	COG3047	cAMP biosynthetic process
GNIT_RS15465	COG5002	protein histidine kinase activity
GNIT_RS15495	COG1131	(ABC) transporter
GNIT_RS15500	COG1283	sodium-dependent phosphate transmembrane transporter activity
GNIT_RS15520	COG0589	response to stress
GNIT_RS15530	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GNIT_RS15535	COG0484	heat shock protein binding
GNIT_RS15540	COG0789	Transcriptional regulator
GNIT_RS15550	COG1301	dicarboxylic acid transport
GNIT_RS15555	COG0589	response to stress
GNIT_RS15560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GNIT_RS15565	COG4191	Histidine kinase
GNIT_RS15580	COG1472	Belongs to the glycosyl hydrolase 3 family
GNIT_RS15620	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GNIT_RS15640	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GNIT_RS15645	COG2198	Histidine kinase
GNIT_RS15645	COG0784	Response regulator, receiver
GNIT_RS15645	COG5002	protein histidine kinase activity
GNIT_RS15650	COG2201	protein-glutamate methylesterase activity
GNIT_RS15655	COG1757	Na H antiporter
GNIT_RS15690	COG0330	HflC and HflK could
GNIT_RS15700	COG2133	pyrroloquinoline quinone binding
GNIT_RS15705	COG1404	Belongs to the peptidase S8 family
GNIT_RS15710	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GNIT_RS15715	COG0840	transmembrane signaling receptor activity
GNIT_RS15720	COG2223	nitrite transmembrane transporter activity
GNIT_RS15740	COG3383	formate dehydrogenase (NAD+) activity
GNIT_RS15745	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GNIT_RS15755	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GNIT_RS15760	COG2199	diguanylate cyclase activity
GNIT_RS15785	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GNIT_RS15795	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GNIT_RS15805	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GNIT_RS15820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GNIT_RS15825	COG2169	Transcriptional regulator
GNIT_RS15825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GNIT_RS15835	COG1166	arginine decarboxylase activity
GNIT_RS15840	COG0745	RESPONSE REGULATOR receiver
GNIT_RS15850	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GNIT_RS15855	COG0303	'Molybdopterin
GNIT_RS15885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GNIT_RS15895	COG4251	negative regulation of phosphorylation
GNIT_RS15900	COG0784	Response regulator, receiver
GNIT_RS15905	COG5001	Diguanylate cyclase
GNIT_RS15905	COG3706	GGDEF domain
GNIT_RS15905	COG4251	negative regulation of phosphorylation
GNIT_RS15905	COG2203	Gaf domain
GNIT_RS15910	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GNIT_RS15915	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GNIT_RS15920	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GNIT_RS15930	COG0356	it plays a direct role in the translocation of protons across the membrane
GNIT_RS15950	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GNIT_RS15955	COG0589	response to stress
GNIT_RS15965	COG3459	Glycosyltransferase 36 associated
GNIT_RS15980	COG0574	Belongs to the PEP-utilizing enzyme family
GNIT_RS15980	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GNIT_RS15985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GNIT_RS16015	COG0577	efflux transmembrane transporter activity
GNIT_RS16015	COG1136	(ABC) transporter
GNIT_RS16020	COG1136	(ABC) transporter
GNIT_RS16025	COG1566	PFAM secretion protein HlyD family protein
GNIT_RS16030	COG2204	response regulator
GNIT_RS16035	COG4191	Histidine kinase
GNIT_RS16060	COG4771	TonB-dependent receptor
GNIT_RS16065	COG1064	alcohol dehydrogenase
GNIT_RS16075	COG2015	COG2015, Alkyl sulfatase and related hydrolases
GNIT_RS16100	COG2409	Drug exporters of the RND superfamily
GNIT_RS16120	COG1278	Cold shock
GNIT_RS16125	COG3706	GGDEF domain
GNIT_RS16130	COG0596	Alpha beta hydrolase
GNIT_RS16135	COG0129	dihydroxy-acid dehydratase activity
GNIT_RS16145	COG2079	MmgE PrpD family protein
GNIT_RS16165	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GNIT_RS16175	COG4191	Histidine kinase
GNIT_RS16180	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GNIT_RS16185	COG1902	pentaerythritol trinitrate reductase activity
GNIT_RS16210	COG2217	Heavy metal translocating P-type atpase
GNIT_RS16225	COG2353	YceI-like domain
GNIT_RS16230	COG0066	3-isopropylmalate dehydratase activity
GNIT_RS16235	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GNIT_RS16240	COG0655	NAD(P)H dehydrogenase (quinone) activity
GNIT_RS16250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GNIT_RS16255	COG1414	Transcriptional regulator
GNIT_RS16260	COG4771	TonB-dependent receptor
GNIT_RS16275	COG1960	acyl-CoA dehydrogenase activity
GNIT_RS16305	COG3030	protein affecting phage T7 exclusion by the F plasmid
GNIT_RS16310	COG4232	protein-disulfide reductase activity
GNIT_RS16325	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GNIT_RS16330	COG0511	ligase activity, forming carbon-carbon bonds
GNIT_RS16335	COG0439	Biotin carboxylase
GNIT_RS16355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GNIT_RS16360	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GNIT_RS16375	COG0151	Belongs to the GarS family
GNIT_RS16380	COG3954	Phosphoribulokinase
GNIT_RS16395	COG2354	Protein conserved in bacteria
GNIT_RS16400	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GNIT_RS16405	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GNIT_RS16410	COG3031	protein transport across the cell outer membrane
GNIT_RS16420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GNIT_RS16425	COG1459	type II secretion system
GNIT_RS16430	COG2165	general secretion pathway protein
GNIT_RS16435	COG2165	general secretion pathway protein
GNIT_RS16440	COG2165	general secretion pathway protein
GNIT_RS16445	COG4795	General secretion pathway protein
GNIT_RS16450	COG3156	type II secretion system protein K
GNIT_RS16460	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GNIT_RS16470	COG2203	Gaf domain
GNIT_RS16470	COG4251	negative regulation of phosphorylation
GNIT_RS16470	COG3706	GGDEF domain
GNIT_RS16470	COG5001	Diguanylate cyclase
GNIT_RS16475	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GNIT_RS16480	COG1011	Hydrolase
GNIT_RS16485	COG0494	nUDIX hydrolase
GNIT_RS16490	COG1218	3'(2'),5'-bisphosphate nucleotidase
GNIT_RS16510	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GNIT_RS16530	COG4221	oxidoreductase activity
GNIT_RS16535	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GNIT_RS16540	COG2943	transferase activity, transferring hexosyl groups
GNIT_RS16555	COG3706	GGDEF domain
GNIT_RS16570	COG3089	Belongs to the UPF0270 family
GNIT_RS16575	COG0429	hydrolase of the alpha beta-hydrolase fold
GNIT_RS16580	COG0488	(ABC) transporter
GNIT_RS16610	COG2900	Belongs to the SlyX family
GNIT_RS16620	COG0545	Peptidyl-prolyl cis-trans isomerase
GNIT_RS16640	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GNIT_RS16670	COG0668	transmembrane transport
GNIT_RS16685	COG2204	response regulator
GNIT_RS16695	COG4251	negative regulation of phosphorylation
GNIT_RS16700	COG2201	protein-glutamate methylesterase activity
GNIT_RS16705	COG0784	Response regulator, receiver
GNIT_RS16705	COG2205	protein histidine kinase activity
GNIT_RS16725	COG4771	TonB-dependent receptor
GNIT_RS16745	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GNIT_RS16750	COG2183	response to ionizing radiation
GNIT_RS16765	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GNIT_RS16770	COG2814	Major facilitator Superfamily
GNIT_RS16780	COG3300	MHYT domain
GNIT_RS16780	COG5001	Diguanylate cyclase
GNIT_RS16805	COG0596	Alpha beta hydrolase
GNIT_RS16810	COG1040	competence protein
GNIT_RS16820	COG0316	Belongs to the HesB IscA family
GNIT_RS16820	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GNIT_RS16835	COG0534	Mate efflux family protein
GNIT_RS16840	COG0726	polysaccharide deacetylase
GNIT_RS16840	COG1649	PFAM Uncharacterised BCR, COG1649
GNIT_RS16855	COG0109	protoheme IX farnesyltransferase activity
GNIT_RS16860	COG1612	heme a metabolic process
GNIT_RS16885	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GNIT_RS16890	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GNIT_RS16895	COG1565	acr, cog1565
GNIT_RS16895	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GNIT_RS16905	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GNIT_RS16920	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GNIT_RS16925	COG0129	dihydroxy-acid dehydratase activity
GNIT_RS16930	COG0606	chelatase, subunit chli
GNIT_RS16935	COG1476	TRANSCRIPTIONal
GNIT_RS16945	COG0583	DNA-binding transcription factor activity
GNIT_RS16960	COG2814	Major facilitator Superfamily
GNIT_RS16970	COG0288	reversible hydration of carbon dioxide
GNIT_RS16980	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GNIT_RS16985	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GNIT_RS17005	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GNIT_RS17035	COG0840	transmembrane signaling receptor activity
GNIT_RS17040	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GNIT_RS17070	COG0425	Belongs to the sulfur carrier protein TusA family
GNIT_RS17080	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GNIT_RS17085	COG1561	YicC-like family, N-terminal region
GNIT_RS17095	COG4774	siderophore transport
GNIT_RS17100	COG3128	pkhd-type hydroxylase
GNIT_RS17105	COG1454	alcohol dehydrogenase
GNIT_RS17110	COG0824	Thioesterase
GNIT_RS17115	COG0500	methyltransferase
GNIT_RS17120	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GNIT_RS17150	COG1136	(ABC) transporter
GNIT_RS17155	COG0577	efflux transmembrane transporter activity
GNIT_RS17155	COG1136	(ABC) transporter
GNIT_RS17170	COG5000	phosphorelay sensor kinase activity
GNIT_RS17175	COG0521	Mo-molybdopterin cofactor biosynthetic process
GNIT_RS17235	COG4628	conserved protein (DUF2132)
GNIT_RS17255	COG0811	peptide transport
GNIT_RS17295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GNIT_RS17330	COG1477	protein flavinylation
GNIT_RS17345	COG1741	Belongs to the pirin family
GNIT_RS17485	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GNIT_RS17490	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GNIT_RS17500	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GNIT_RS17505	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GNIT_RS17510	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GNIT_RS17530	COG1475	DNA binding
GNIT_RS17535	COG1192	Involved in chromosome partitioning
GNIT_RS17540	COG0357	Ribosomal RNA small subunit methyltransferase G
GNIT_RS17545	COG0445	tRNA wobble uridine modification
GNIT_RS17560	COG0716	FMN binding
GNIT_RS17565	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GNIT_RS17570	COG1666	GTP binding
GNIT_RS17575	COG0706	membrane insertase activity
GNIT_RS17580	COG0594	ribonuclease P activity
GNIT_RS17605	COG5002	protein histidine kinase activity
GNIT_RS17605	COG5001	Diguanylate cyclase
GNIT_RS17610	COG2203	Gaf domain
GNIT_RS17610	COG3706	GGDEF domain
GNIT_RS17610	COG4251	negative regulation of phosphorylation
GNIT_RS17610	COG5001	Diguanylate cyclase
GNIT_RS17640	COG2205	protein histidine kinase activity
GNIT_RS17640	COG0784	Response regulator, receiver
GNIT_RS17660	COG1403	HNH endonuclease
GNIT_RS17680	COG1404	Belongs to the peptidase S8 family
GNIT_RS17685	COG5002	protein histidine kinase activity
GNIT_RS17685	COG2205	protein histidine kinase activity
GNIT_RS17685	COG0784	Response regulator, receiver
GNIT_RS17705	COG3119	arylsulfatase activity
GNIT_RS17740	COG1404	Belongs to the peptidase S8 family
GNIT_RS17755	COG0154	amidase activity
GNIT_RS17770	COG0784	Response regulator, receiver
GNIT_RS17770	COG2205	protein histidine kinase activity
GNIT_RS17780	COG2205	protein histidine kinase activity
GNIT_RS17780	COG0784	Response regulator, receiver